# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RHSP PF07999.11 EGG13256.1 - 0.0036 16.2 0.1 0.018 13.9 0.1 2.1 1 1 0 1 1 1 1 Retrotransposon hot spot protein DUF3398 PF11878.8 EGG13256.1 - 0.012 16.1 2.0 0.043 14.2 2.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) AAA_16 PF13191.6 EGG13256.1 - 0.064 13.6 0.1 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF3439 PF11921.8 EGG13256.1 - 3.7 7.5 11.9 9.3 6.2 11.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SET PF00856.28 EGG13257.1 - 2e-13 51.1 10.2 1.1e-12 48.7 0.0 3.7 4 0 0 4 4 4 2 SET domain Rubis-subs-bind PF09273.11 EGG13257.1 - 2.7e-10 41.0 12.7 8.5e-10 39.4 9.7 3.0 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding TPR_11 PF13414.6 EGG13257.1 - 0.00017 21.2 0.5 0.00044 19.9 0.5 1.7 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EGG13257.1 - 0.00047 20.1 0.1 0.0015 18.5 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG13257.1 - 0.00061 19.5 0.2 0.0021 17.8 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Pox_D5 PF03288.16 EGG13257.1 - 0.16 12.4 0.0 0.16 12.4 0.0 3.5 3 0 0 3 3 3 0 Poxvirus D5 protein-like Arrestin_N PF00339.29 EGG13258.1 - 0.0082 16.2 2.8 0.26 11.3 0.1 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Secretin_N_2 PF07655.13 EGG13258.1 - 0.017 15.7 16.2 0.017 15.7 16.2 7.0 5 2 0 5 5 5 0 Secretin N-terminal domain Pkinase PF00069.25 EGG13259.1 - 6.9e-52 176.4 1.2 1.3e-51 175.5 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13259.1 - 2.1e-47 161.6 0.0 4.1e-47 160.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG13259.1 - 0.0093 14.8 0.3 0.0093 14.8 0.3 2.1 2 0 0 2 2 2 1 Fungal protein kinase TFIIA PF03153.13 EGG13259.1 - 0.034 14.1 11.2 0.023 14.7 6.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Kdo PF06293.14 EGG13259.1 - 0.071 12.5 1.1 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0203 PF05254.12 EGG13260.1 - 3.8e-14 52.7 0.8 3.9e-14 52.6 0.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 EGG13260.1 - 0.0021 18.4 1.2 0.0048 17.2 1.2 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 EGG13260.1 - 0.0028 17.6 1.4 0.12 12.4 0.4 2.5 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Ribosomal_L32p PF01783.23 EGG13260.1 - 0.012 15.8 0.1 0.018 15.3 0.1 1.2 1 0 0 1 1 1 0 Ribosomal L32p protein family Dynactin_p22 PF07426.11 EGG13261.1 - 1.2e-18 67.5 8.0 6.4e-18 65.2 4.9 2.1 2 0 0 2 2 2 1 Dynactin subunit p22 Phi-29_GP16_7 PF06720.11 EGG13261.1 - 0.0024 17.7 5.0 0.036 13.9 0.4 2.4 2 0 0 2 2 2 2 Bacteriophage phi-29 early protein GP16.7 Arm-DNA-bind_5 PF17293.2 EGG13261.1 - 0.0071 16.8 0.1 0.21 12.0 0.0 2.5 2 0 0 2 2 2 1 Arm DNA-binding domain Glycoprot_B_PH2 PF17417.2 EGG13261.1 - 0.07 13.5 1.9 2.2 8.6 0.3 2.4 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain PCAF_N PF06466.11 EGG13261.1 - 0.83 9.2 3.9 0.59 9.7 0.9 2.4 2 1 0 2 2 2 0 PCAF (P300/CBP-associated factor) N-terminal domain EST1 PF10374.9 EGG13261.1 - 1.8 9.2 7.3 1.1 9.9 0.2 3.0 2 1 1 3 3 3 0 Telomerase activating protein Est1 NPV_P10 PF05531.12 EGG13261.1 - 2.2 8.8 7.7 0.92 10.0 0.7 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SPACA9 PF15120.6 EGG13261.1 - 3.9 7.2 7.9 1 9.1 2.7 2.1 1 1 0 2 2 2 0 Sperm acrosome-associated protein 9 GN3L_Grn1 PF08701.11 EGG13262.1 - 1 9.5 18.9 1.8 8.7 18.9 1.4 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase Transket_pyr PF02779.24 EGG13264.1 - 2.7e-65 219.3 0.0 4.8e-65 218.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EGG13264.1 - 2e-63 214.1 0.0 2.9e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EGG13264.1 - 3e-49 166.6 0.0 5.1e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EGG13264.1 - 3.5e-17 61.7 1.6 1.1e-16 60.1 1.6 1.9 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus adh_short PF00106.25 EGG13265.1 - 3e-46 157.3 0.1 4e-46 156.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG13265.1 - 7.5e-30 104.2 0.0 9.5e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG13265.1 - 3.2e-08 33.7 0.0 5.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EGG13265.1 - 0.0018 18.5 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EGG13265.1 - 0.0046 16.9 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EGG13265.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MMR_HSR1_Xtn PF16897.5 EGG13266.1 - 1.6e-43 147.0 0.2 2.9e-43 146.2 0.2 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EGG13266.1 - 6.1e-21 74.6 0.0 1.4e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EGG13266.1 - 3.2e-19 68.7 0.0 5.9e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EGG13266.1 - 4.6e-11 42.5 0.1 1.5e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGG13266.1 - 0.0016 18.5 0.2 1.8 8.6 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 EGG13266.1 - 0.0052 15.8 0.3 0.017 14.1 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DAGK_cat PF00781.24 EGG13267.1 - 1.3e-32 112.1 0.0 2.8e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain tRNA_Me_trans PF03054.16 EGG13268.1 - 2.2e-99 332.6 6.4 1e-94 317.3 1.4 2.1 1 1 1 2 2 2 2 tRNA methyl transferase Asn_synthase PF00733.21 EGG13268.1 - 0.00054 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 EGG13268.1 - 0.00056 19.5 0.0 0.092 12.3 0.0 2.5 2 1 0 2 2 2 2 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 EGG13268.1 - 0.00063 18.9 0.0 0.0026 16.9 0.0 2.1 2 0 0 2 2 2 1 NAD synthase SUIM_assoc PF16619.5 EGG13268.1 - 0.0013 18.7 8.8 0.027 14.6 2.1 2.7 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 ATP_bind_3 PF01171.20 EGG13268.1 - 0.016 14.9 0.6 0.016 14.9 0.6 2.9 2 1 0 2 2 2 0 PP-loop family CPW_WPC PF09717.10 EGG13268.1 - 0.032 15.2 0.5 0.93 10.5 0.3 2.8 2 0 0 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) CH PF00307.31 EGG13269.1 - 3.4e-11 43.3 0.0 3.4e-11 43.3 0.0 3.6 4 0 0 4 4 4 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGG13269.1 - 0.007 16.2 0.2 0.27 11.1 0.0 3.1 2 0 0 2 2 2 1 CAMSAP CH domain DUF3446 PF11928.8 EGG13269.1 - 0.64 10.4 16.4 0.29 11.5 12.5 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain DAP3 PF10236.9 EGG13270.1 - 1.7e-28 99.7 0.1 3.4e-28 98.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 EGG13270.1 - 0.00042 20.3 0.2 0.29 11.0 0.1 2.4 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 EGG13270.1 - 0.021 14.6 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG13270.1 - 0.032 14.6 0.0 0.13 12.6 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGG13270.1 - 0.069 13.4 0.0 0.2 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGG13270.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DEP PF00610.21 EGG13271.1 - 4.4e-07 29.9 0.0 1.7e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PP2C_2 PF13672.6 EGG13271.1 - 0.00093 18.9 0.0 0.12 12.0 0.0 2.6 2 0 0 2 2 2 2 Protein phosphatase 2C WAC_Acf1_DNA_bd PF10537.9 EGG13273.1 - 5.5e-25 87.8 0.5 5.5e-25 87.8 0.5 2.7 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.17 EGG13273.1 - 3.5e-17 62.5 3.1 7.1e-17 61.5 3.1 1.6 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 EGG13273.1 - 4e-13 49.7 1.5 4e-13 49.7 1.5 5.7 4 2 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 EGG13273.1 - 2.6e-09 36.4 0.1 8.5e-09 34.7 0.0 2.0 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 COesterase PF00135.28 EGG13274.1 - 3e-125 419.0 0.0 4.2e-125 418.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG13274.1 - 3.8e-10 40.0 0.0 5.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG13274.1 - 0.032 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Mycobact_memb PF05423.13 EGG13274.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Mycobacterium membrane protein zf-Nse PF11789.8 EGG13275.1 - 3e-19 68.6 0.9 5.9e-19 67.6 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGG13275.1 - 3.6e-06 26.9 0.5 6.6e-06 26.1 0.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 EGG13275.1 - 0.00035 20.0 0.4 0.0012 18.3 0.1 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-MIZ PF02891.20 EGG13275.1 - 0.0014 18.4 0.7 0.0026 17.5 0.7 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.6 EGG13275.1 - 0.066 13.1 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Erf4 PF10256.9 EGG13275.1 - 0.092 12.9 0.8 0.37 10.9 0.1 2.2 2 1 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family zf-C3HC4 PF00097.25 EGG13275.1 - 0.11 12.4 0.3 0.23 11.3 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGG13275.1 - 0.15 11.7 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 EGG13275.1 - 0.15 12.3 0.1 0.33 11.3 0.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain CPSF_A PF03178.15 EGG13276.1 - 2e-66 224.5 0.8 3.2e-52 177.9 0.1 3.3 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.9 EGG13276.1 - 1.2e-30 106.6 7.0 1.2e-30 106.6 7.0 3.6 4 2 0 4 4 4 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term SPX PF03105.19 EGG13276.1 - 1.3 8.9 39.7 0.52 10.2 3.6 4.3 4 0 0 4 4 4 0 SPX domain Med21 PF11221.8 EGG13277.1 - 4.3e-22 78.9 6.3 5.2e-22 78.7 6.3 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex BST2 PF16716.5 EGG13277.1 - 0.62 10.7 11.7 0.14 12.8 8.6 1.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Orf78 PF06024.12 EGG13278.1 - 8.4e-05 22.8 3.2 8.4e-05 22.8 3.2 4.2 4 0 0 4 4 4 1 Orf78 (ac78) TbpB_A PF17484.2 EGG13278.1 - 0.025 15.3 5.2 0.063 14.0 5.2 1.6 1 0 0 1 1 1 0 N-Lobe handle Tf-binding protein B DUF2370 PF10176.9 EGG13278.1 - 0.4 10.3 3.7 0.63 9.6 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF3439 PF11921.8 EGG13278.1 - 1.3 9.0 10.5 0.97 9.4 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) ADH_N PF08240.12 EGG13279.1 - 4.1e-24 84.6 2.0 8.5e-24 83.5 2.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGG13279.1 - 3.8e-22 78.7 0.1 1.1e-21 77.1 0.1 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 EGG13279.1 - 0.0013 18.3 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glu_dehyd_C PF16912.5 EGG13279.1 - 0.0016 18.0 0.1 0.0063 16.0 0.1 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGG13279.1 - 0.0021 19.1 0.0 0.0047 18.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGG13279.1 - 0.013 14.8 0.2 0.024 14.0 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EGG13279.1 - 0.025 14.8 0.1 0.044 14.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain MOSC PF03473.17 EGG13280.1 - 0.0024 17.9 0.0 0.0059 16.6 0.0 1.7 2 1 0 2 2 2 1 MOSC domain Pkinase PF00069.25 EGG13281.1 - 3.6e-51 174.1 0.9 3.6e-51 174.1 0.9 3.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13281.1 - 1.1e-26 93.7 0.1 1.1e-26 93.7 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4164 PF13747.6 EGG13281.1 - 0.024 14.9 0.8 0.024 14.9 0.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) PWWP PF00855.17 EGG13282.1 - 2.4e-17 63.1 0.1 9.4e-17 61.2 0.1 2.1 1 0 0 1 1 1 1 PWWP domain SDA1 PF05285.12 EGG13282.1 - 0.52 9.7 34.0 4.7 6.5 34.0 2.1 1 1 0 1 1 1 0 SDA1 dCMP_cyt_deam_1 PF00383.23 EGG13283.1 - 3.2e-17 62.3 0.3 3.8e-17 62.0 0.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EGG13283.1 - 1.4e-11 44.7 0.2 1.5e-09 38.1 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region ABC2_membrane PF01061.24 EGG13284.1 - 1.6e-68 230.2 70.0 2.6e-37 128.3 25.5 4.4 3 1 1 4 4 4 3 ABC-2 type transporter ABC_tran PF00005.27 EGG13284.1 - 1.3e-43 148.8 7.1 6.7e-22 78.5 0.0 3.3 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EGG13284.1 - 3.2e-06 27.2 6.7 0.0043 16.9 0.1 4.4 4 1 1 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGG13284.1 - 6.8e-06 26.6 0.0 0.096 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGG13284.1 - 3.5e-05 24.1 0.8 0.49 10.7 0.0 3.3 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 EGG13284.1 - 4.5e-05 23.4 0.6 0.003 17.5 0.2 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EGG13284.1 - 0.0011 18.6 0.1 0.036 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGG13284.1 - 0.0012 19.4 2.6 1.3 9.6 0.0 3.9 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.6 EGG13284.1 - 0.0016 18.1 1.0 0.018 14.8 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.6 EGG13284.1 - 0.0048 17.3 0.2 0.055 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGG13284.1 - 0.011 15.0 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 EGG13284.1 - 0.056 13.7 0.1 2.3 8.5 0.0 3.3 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EGG13284.1 - 0.072 13.5 0.1 16 5.9 0.0 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGG13284.1 - 0.13 12.5 0.3 1.8 8.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGG13284.1 - 0.17 12.0 3.4 4.2 7.5 0.0 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EGG13284.1 - 0.24 11.6 0.8 2.9 8.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Menin PF05053.13 EGG13284.1 - 2.1 6.6 12.5 3.4 5.9 12.5 1.2 1 0 0 1 1 1 0 Menin DUF2464 PF10240.9 EGG13284.1 - 4.2 6.8 12.4 9.1 5.8 12.4 1.5 1 0 0 1 1 1 0 Multivesicular body subunit 12 Androgen_recep PF02166.16 EGG13284.1 - 5.3 5.8 5.5 11 4.7 5.5 1.4 1 0 0 1 1 1 0 Androgen receptor Presenilin PF01080.17 EGG13284.1 - 9.5 4.9 15.6 3.4 6.3 9.3 2.5 2 0 0 2 2 2 0 Presenilin Macoilin PF09726.9 EGG13285.1 - 0.00072 18.3 56.7 0.00072 18.3 56.7 2.7 1 1 1 2 2 2 1 Macoilin family DER1 PF04511.15 EGG13286.1 - 1.3e-38 132.9 11.4 1.4e-29 103.4 8.7 2.0 1 1 1 2 2 2 2 Der1-like family ORMDL PF04061.14 EGG13287.1 - 7.6e-48 161.8 3.6 8.7e-48 161.6 3.6 1.0 1 0 0 1 1 1 1 ORMDL family DUF2868 PF11067.8 EGG13287.1 - 0.014 14.9 1.4 0.021 14.4 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) CCB1 PF12046.8 EGG13287.1 - 0.035 13.4 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B EamA PF00892.20 EGG13288.1 - 3.6e-17 62.8 33.1 3.8e-08 33.6 11.7 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 EGG13288.1 - 2.8e-08 33.6 12.0 4.5e-08 33.0 12.0 1.3 1 0 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 EGG13288.1 - 3.6e-07 29.7 3.4 3.6e-07 29.7 3.4 1.8 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 EGG13288.1 - 6.8e-06 25.6 5.8 1.1e-05 24.9 5.8 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family EmrE PF13536.6 EGG13288.1 - 5.8e-05 22.8 2.6 0.00015 21.5 2.6 1.7 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter CRT-like PF08627.10 EGG13288.1 - 0.0027 16.7 7.9 0.083 11.8 2.8 2.5 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like DUF3955 PF13127.6 EGG13288.1 - 0.012 15.4 5.6 0.012 15.4 5.6 3.6 6 0 0 6 6 6 0 Protein of unknown function (DUF3955) Alpha_kinase PF02816.18 EGG13289.1 - 6.3e-59 199.2 0.2 6.3e-59 199.2 0.2 3.1 3 0 0 3 3 3 1 Alpha-kinase family WD40 PF00400.32 EGG13289.1 - 3e-44 148.1 18.9 4.8e-07 30.4 0.2 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 EGG13289.1 - 2.1e-12 46.5 3.7 0.0013 17.5 0.3 5.9 2 1 4 6 6 6 5 Nucleoporin Nup120/160 WD40_like PF17005.5 EGG13289.1 - 3.6e-06 26.5 1.2 0.0033 16.8 0.1 2.6 1 1 0 2 2 2 2 WD40-like domain YmzC PF14157.6 EGG13289.1 - 0.00062 19.8 0.7 0.1 12.7 0.1 4.3 5 0 0 5 5 5 1 YmzC-like protein Menin PF05053.13 EGG13289.1 - 1.5 7.1 5.4 2.9 6.1 5.4 1.4 1 0 0 1 1 1 0 Menin DUF775 PF05603.12 EGG13289.1 - 2 7.9 9.5 2.5 7.6 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF775) PP2C PF00481.21 EGG13290.1 - 9e-47 159.9 0.0 9e-47 159.9 0.0 2.0 2 1 0 2 2 1 1 Protein phosphatase 2C ABC2_membrane PF01061.24 EGG13290.1 - 7.5e-39 133.3 26.1 7.5e-39 133.3 26.1 2.8 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 EGG13290.1 - 1.2e-22 80.9 0.0 1.2e-22 80.9 0.0 2.8 2 1 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 EGG13290.1 - 5.9e-06 26.3 10.3 0.00036 20.4 0.1 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGG13290.1 - 0.00011 21.4 12.8 0.00011 21.4 12.8 3.9 3 1 0 3 3 2 1 ABC-2 family transporter protein CENP-F_leu_zip PF10473.9 EGG13290.1 - 0.0049 16.9 17.8 0.01 15.9 17.8 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.11 EGG13290.1 - 0.0068 16.6 13.4 0.24 11.7 7.8 3.2 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 AAA_18 PF13238.6 EGG13290.1 - 0.017 15.7 2.8 0.13 12.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGG13290.1 - 0.12 12.1 0.3 0.42 10.4 0.2 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4407 PF14362.6 EGG13290.1 - 0.49 9.7 7.8 14 5.0 8.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 EGG13290.1 - 0.71 9.7 16.2 0.83 9.5 3.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Prefoldin PF02996.17 EGG13290.1 - 2.7 7.9 14.6 1 9.3 3.2 2.5 2 0 0 2 2 2 0 Prefoldin subunit DUF4472 PF14739.6 EGG13290.1 - 6.9 7.5 17.1 0.31 11.8 3.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) DUF948 PF06103.11 EGG13290.1 - 8.7 6.7 5.7 2.2 8.6 1.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Synaptobrevin PF00957.21 EGG13290.1 - 9.4 6.1 8.4 3.2 7.6 0.9 3.1 2 0 0 2 2 2 0 Synaptobrevin GDP_Man_Dehyd PF16363.5 EGG13291.1 - 5e-60 203.6 0.0 6.2e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG13291.1 - 1.1e-53 182.2 0.0 1.3e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGG13291.1 - 3.8e-16 59.1 0.0 2.2e-15 56.5 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGG13291.1 - 3.7e-15 55.7 0.2 1.2e-14 54.0 0.2 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGG13291.1 - 5.8e-10 38.7 0.0 8.9e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EGG13291.1 - 2.7e-09 37.2 0.1 7.4e-09 35.8 0.1 1.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EGG13291.1 - 4.6e-08 32.7 0.1 1e-07 31.6 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EGG13291.1 - 1.7e-05 24.8 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGG13291.1 - 0.00012 21.4 0.0 0.013 14.7 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EGG13291.1 - 0.025 14.1 0.4 0.27 10.8 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family WD-3 PF09765.9 EGG13292.1 - 3e-52 177.7 1.2 3.9e-52 177.4 1.2 1.1 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 EGG13292.1 - 7.1e-22 77.4 6.2 1.6e-21 76.3 6.2 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING-like PF08746.11 EGG13292.1 - 0.017 15.5 3.0 0.06 13.7 3.0 2.0 1 1 0 1 1 1 0 RING-like domain zf-RING_2 PF13639.6 EGG13292.1 - 0.19 12.1 11.0 0.3 11.4 7.6 2.8 2 1 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.7 EGG13292.1 - 3.2 8.1 9.5 0.6 10.4 5.4 2.0 2 1 0 2 2 2 0 RING-H2 zinc finger domain FAM60A PF15396.6 EGG13293.1 - 1.4 8.9 7.4 2.4 8.1 7.4 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Senescence_reg PF04520.13 EGG13293.1 - 5.3 7.8 7.9 8.1 7.3 7.9 1.2 1 0 0 1 1 1 0 Senescence regulator Roughex PF06020.11 EGG13294.1 - 1.4 8.0 7.0 2 7.4 7.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Ecl1 PF12855.7 EGG13294.1 - 2.3 9.4 14.0 3.7 8.7 1.5 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins DUF908 PF06012.12 EGG13294.1 - 2.8 7.3 10.6 1.1 8.6 4.5 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DUF4326 PF14216.6 EGG13295.1 - 3.4e-24 85.4 0.8 5.5e-24 84.7 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) IF-2B PF01008.17 EGG13296.1 - 9.6e-70 235.0 0.1 9.6e-70 235.0 0.1 1.3 2 0 0 2 2 2 1 Initiation factor 2 subunit family AAA_16 PF13191.6 EGG13297.1 - 1.6e-05 25.3 0.0 3.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG13297.1 - 0.0022 18.3 0.0 0.033 14.5 0.0 2.7 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 EGG13297.1 - 0.032 14.2 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 EGG13297.1 - 0.083 12.2 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 EGG13297.1 - 0.11 12.9 0.4 1.5 9.2 0.0 2.8 2 1 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 EGG13297.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1160 PF06648.11 EGG13297.1 - 0.6 10.1 2.9 1.2 9.1 0.1 2.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1160) AAA_16 PF13191.6 EGG13298.1 - 0.00073 20.0 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG13298.1 - 0.002 18.4 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 EGG13298.1 - 0.0032 17.3 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Bacterial dnaA protein NACHT PF05729.12 EGG13298.1 - 0.059 13.3 0.0 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain DUF3969 PF13108.6 EGG13298.1 - 0.3 11.1 1.8 1.7 8.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) HALZ PF02183.18 EGG13299.1 - 0.00023 21.3 0.0 0.00052 20.2 0.0 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper Cnn_1N PF07989.11 EGG13299.1 - 0.00032 20.8 4.1 0.00047 20.3 3.4 1.8 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 DivIC PF04977.15 EGG13299.1 - 0.0055 16.4 1.8 0.0055 16.4 1.8 1.7 2 0 0 2 2 2 1 Septum formation initiator MbeD_MobD PF04899.12 EGG13299.1 - 0.011 15.8 0.3 0.019 15.1 0.3 1.3 1 0 0 1 1 1 0 MbeD/MobD like DUF1640 PF07798.11 EGG13299.1 - 0.011 15.8 0.7 0.016 15.2 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Seryl_tRNA_N PF02403.22 EGG13299.1 - 0.032 14.5 2.5 0.037 14.2 2.5 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.21 EGG13299.1 - 0.041 14.0 2.7 0.043 13.9 1.2 1.8 1 1 1 2 2 2 0 bZIP transcription factor Spc7 PF08317.11 EGG13299.1 - 0.048 12.5 3.0 0.052 12.4 3.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Vps39_1 PF10366.9 EGG13299.1 - 0.065 13.5 0.5 0.077 13.3 0.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Shugoshin_N PF07558.11 EGG13299.1 - 0.072 13.0 0.3 0.37 10.7 0.1 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Prominin PF05478.11 EGG13299.1 - 0.074 11.0 0.4 0.088 10.8 0.4 1.1 1 0 0 1 1 1 0 Prominin Matrilin_ccoil PF10393.9 EGG13299.1 - 0.092 12.6 1.0 0.28 11.1 0.7 1.9 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin SlyX PF04102.12 EGG13299.1 - 0.095 13.3 1.0 1.5 9.5 1.3 2.0 1 1 1 2 2 2 0 SlyX FlaC_arch PF05377.11 EGG13299.1 - 0.29 11.5 3.4 0.27 11.7 0.5 2.1 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 EGG13299.1 - 0.3 11.6 5.4 0.17 12.4 2.8 1.8 1 1 1 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 EGG13299.1 - 0.91 10.1 5.6 1.8 9.1 5.6 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region NIPSNAP PF07978.13 EGG13300.1 - 1.9e-44 150.0 0.1 5.7e-23 81.1 0.1 3.0 3 0 0 3 3 3 2 NIPSNAP Propeptide_C25 PF08126.11 EGG13301.1 - 0.026 13.6 0.2 0.041 13.0 0.2 1.3 1 0 0 1 1 1 0 Propeptide_C25 Mucin PF01456.17 EGG13301.1 - 3.5 7.6 15.9 9.1 6.3 11.1 2.1 1 1 1 2 2 2 0 Mucin-like glycoprotein Ribosomal_S7e PF01251.18 EGG13302.1 - 5.5e-79 264.2 4.4 6.3e-79 264.0 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Actin PF00022.19 EGG13303.1 - 3.1e-125 418.0 0.0 1.3e-124 415.9 0.0 1.7 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 EGG13303.1 - 0.034 13.3 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative actin-like family SMC_N PF02463.19 EGG13304.1 - 5.4e-17 62.0 43.6 7.8e-15 54.9 43.6 3.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGG13304.1 - 2.6e-15 57.0 6.4 2.6e-15 57.0 6.4 4.8 3 2 1 4 4 4 1 AAA ATPase domain AAA_23 PF13476.6 EGG13304.1 - 1.7e-12 48.2 30.5 1.7e-12 48.2 30.5 6.6 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.6 EGG13304.1 - 0.0005 19.7 0.0 0.0018 18.0 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.7 EGG13304.1 - 0.004 17.3 16.9 0.004 17.3 16.9 7.1 3 2 3 7 7 7 1 Tropomyosin like Occludin_ELL PF07303.13 EGG13304.1 - 0.012 16.3 7.8 0.012 16.3 7.8 7.8 3 2 7 10 10 10 0 Occludin homology domain ABC_tran PF00005.27 EGG13304.1 - 0.11 13.0 0.0 0.11 13.0 0.0 6.6 4 2 0 4 4 4 0 ABC transporter Baculo_PEP_C PF04513.12 EGG13304.1 - 0.91 9.6 25.0 3.3 7.8 2.0 5.0 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_21 PF13304.6 EGG13304.1 - 2 8.2 11.6 0.29 10.9 0.2 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system LisH_TPL PF17814.1 EGG13305.1 - 0.0052 16.4 1.3 0.018 14.7 1.3 2.0 1 0 0 1 1 1 1 LisH-like dimerisation domain Cyclin PF08613.11 EGG13306.1 - 7.2e-07 29.7 2.5 7.2e-07 29.7 2.5 2.3 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGG13306.1 - 0.0027 17.5 0.6 0.0027 17.5 0.6 2.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain MTBP_C PF14920.6 EGG13306.1 - 1.3 8.7 18.0 3.3 7.4 1.9 2.1 2 0 0 2 2 2 0 MDM2-binding Suf PF05843.14 EGG13306.1 - 4.2 7.3 18.7 1.9 8.4 6.6 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3438 PF11920.8 EGG13306.1 - 4.4 6.5 13.9 0.43 9.8 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3438) CCDC53 PF10152.9 EGG13306.1 - 7.4 7.0 14.0 16 5.9 0.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex UPF0121 PF03661.13 EGG13307.1 - 4.5e-31 108.1 10.4 8.8e-31 107.1 10.4 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) Pex14_N PF04695.13 EGG13307.1 - 0.00018 22.2 4.8 0.00037 21.2 4.8 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SSP160 PF06933.11 EGG13307.1 - 0.0032 15.7 13.7 0.0044 15.3 13.7 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Sec10 PF07393.11 EGG13307.1 - 0.073 11.5 4.4 0.11 10.9 4.4 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 PetN PF03742.14 EGG13307.1 - 0.087 12.7 0.4 0.19 11.6 0.4 1.5 1 0 0 1 1 1 0 PetN Kinocilin PF15033.6 EGG13307.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.0 2 0 0 2 2 1 0 Kinocilin protein DUF4614 PF15391.6 EGG13307.1 - 0.41 10.6 13.7 0.63 10.0 13.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 EGG13307.1 - 0.44 9.4 10.1 0.59 8.9 10.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 EGG13307.1 - 0.93 8.6 15.4 1.3 8.2 15.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NAM-associated PF14303.6 EGG13307.1 - 1.1 9.9 12.5 1.7 9.3 12.5 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain FAM199X PF15814.5 EGG13307.1 - 1.7 7.7 13.4 2.6 7.0 13.4 1.2 1 0 0 1 1 1 0 Protein family FAM199X RAP1 PF07218.11 EGG13307.1 - 2.6 6.2 13.9 3.4 5.8 13.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAP1 PF08601.10 EGG13307.1 - 3.7 7.2 22.6 5.1 6.7 22.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 2OG-FeII_Oxy_3 PF13640.6 EGG13308.1 - 3.3e-10 40.7 0.0 5.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SNF2_N PF00176.23 EGG13309.1 - 3.8e-71 239.6 5.1 3.5e-70 236.5 5.1 2.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG13309.1 - 1.9e-18 66.8 3.5 5.8e-18 65.3 0.0 3.4 4 0 0 4 4 3 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 EGG13309.1 - 5e-06 26.4 7.1 1.7e-05 24.7 7.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG13309.1 - 3.5e-05 23.5 7.1 3.5e-05 23.5 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG13309.1 - 5.7e-05 23.0 7.0 5.7e-05 23.0 7.0 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGG13309.1 - 0.00013 21.8 7.8 0.00013 21.8 7.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG13309.1 - 0.00025 20.8 5.9 0.00025 20.8 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGG13309.1 - 0.0003 20.9 6.1 0.0003 20.9 6.1 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGG13309.1 - 0.00092 19.5 8.0 0.00092 19.5 8.0 2.5 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EGG13309.1 - 0.0068 16.2 13.8 0.0071 16.2 8.1 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EGG13309.1 - 0.017 15.0 2.9 0.047 13.6 2.9 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HGTP_anticodon PF03129.20 EGG13309.1 - 9.2 6.5 6.1 1.5 9.0 0.1 2.6 3 0 0 3 3 3 0 Anticodon binding domain Kelch_3 PF13415.6 EGG13311.1 - 2.6e-39 132.8 8.8 6.3e-10 39.1 0.0 7.8 8 0 0 8 8 8 6 Galactose oxidase, central domain RhoGAP PF00620.27 EGG13311.1 - 4.3e-36 124.0 3.7 4.8e-36 123.9 0.1 2.7 3 0 0 3 3 3 1 RhoGAP domain Kelch_5 PF13854.6 EGG13311.1 - 1.1e-34 117.9 6.1 2.4e-07 30.6 1.4 7.4 6 1 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGG13311.1 - 1.2e-33 114.8 16.1 5.2e-10 39.2 0.1 7.5 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.15 EGG13311.1 - 1.5e-33 113.5 2.2 8.4e-07 28.7 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EGG13311.1 - 6.3e-26 89.7 1.6 0.00034 20.1 0.0 7.1 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 EGG13311.1 - 7.1e-23 80.1 16.1 0.00033 20.8 1.6 7.3 3 2 3 6 6 6 6 Kelch motif DUF3915 PF13054.6 EGG13311.1 - 0.98 9.4 8.4 1.1 9.2 1.1 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Ion_trans PF00520.31 EGG13312.1 - 1.3e-27 96.6 72.4 8.3e-17 61.2 38.8 2.8 3 0 0 3 3 3 2 Ion transport protein EF-hand_1 PF00036.32 EGG13312.1 - 2.5e-06 26.6 0.1 0.0032 16.9 0.1 3.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGG13312.1 - 8e-06 26.2 0.0 2.9e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGG13312.1 - 1.1e-05 25.0 0.2 0.16 12.0 0.1 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGG13312.1 - 0.0079 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair zf-primase PF09329.11 EGG13313.1 - 0.00098 18.9 5.4 0.002 17.9 5.4 1.4 1 0 0 1 1 1 1 Primase zinc finger RXT2_N PF08595.11 EGG13313.1 - 7.7 6.5 10.8 2 8.4 2.8 2.6 3 0 0 3 3 3 0 RXT2-like, N-terminal zf-primase PF09329.11 EGG13315.1 - 0.00037 20.2 5.4 0.00081 19.2 5.4 1.5 1 0 0 1 1 1 1 Primase zinc finger Secretin_N_2 PF07655.13 EGG13315.1 - 0.00045 20.7 8.9 0.00045 20.7 8.9 1.7 2 0 0 2 2 2 1 Secretin N-terminal domain Pex2_Pex12 PF04757.14 EGG13315.1 - 0.13 11.8 2.0 0.49 9.9 2.7 1.6 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region DUF1754 PF08555.10 EGG13315.1 - 5.2 7.9 16.5 12 6.8 2.2 2.6 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) FAM176 PF14851.6 EGG13315.1 - 6.4 6.4 12.0 2.6 7.7 1.4 2.3 2 0 0 2 2 2 0 FAM176 family WD40 PF00400.32 EGG13316.1 - 6.5e-53 175.5 19.2 8.7e-09 35.9 1.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG13316.1 - 2.7e-12 46.8 0.4 0.021 15.1 0.0 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG13316.1 - 1.2e-05 24.2 2.5 1.3 7.6 0.0 4.0 1 1 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 EGG13316.1 - 0.00046 20.1 0.2 0.018 14.9 0.1 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGG13316.1 - 0.0012 18.2 0.0 1.8 7.8 0.0 2.6 1 1 0 2 2 2 2 WD40-like domain PD40 PF07676.12 EGG13316.1 - 0.038 13.9 0.0 8.9 6.4 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RhoGAP PF00620.27 EGG13317.1 - 1.5e-35 122.3 3.1 1.8e-35 122.0 0.6 2.3 2 0 0 2 2 2 1 RhoGAP domain DUF489 PF04356.12 EGG13317.1 - 0.014 15.4 0.1 0.05 13.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF4248 PF14053.6 EGG13317.1 - 0.095 12.7 0.2 2.7 8.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DUF806 PF05657.11 EGG13318.1 - 0.051 14.1 1.8 2.3 8.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF806) ERO1 PF04137.15 EGG13319.1 - 5.9e-72 242.8 3.1 6.5e-43 147.3 0.3 5.2 5 1 1 6 6 6 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Ank_2 PF12796.7 EGG13319.1 - 4e-16 59.4 2.7 5.7e-06 26.8 0.1 5.3 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG13319.1 - 9.1e-10 38.9 4.1 0.003 18.1 0.0 6.5 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG13319.1 - 7.2e-08 32.6 2.2 6.3 7.3 0.1 6.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG13319.1 - 2.9e-06 27.2 1.3 46 5.1 0.0 8.4 6 2 2 8 8 8 0 Ankyrin repeat HIT PF01230.23 EGG13320.1 - 2.2e-24 86.0 0.0 3.4e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGG13320.1 - 2.7e-21 76.2 0.0 3.9e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CDH PF02611.15 EGG13320.1 - 0.014 15.0 0.3 0.035 13.7 0.3 1.6 1 1 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase DUF2016 PF09436.10 EGG13320.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2016) Pantoate_ligase PF02569.15 EGG13321.1 - 7.1e-88 294.3 0.0 8e-88 294.1 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase FNIP PF05725.12 EGG13322.1 - 1.6e-18 66.6 51.2 0.02 15.0 0.1 16.1 14 2 2 16 16 16 10 FNIP Repeat DUF2931 PF11153.8 EGG13322.1 - 0.093 12.4 0.0 27 4.4 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2931) Mito_carr PF00153.27 EGG13323.1 - 4.5e-05 23.3 0.0 0.35 10.8 0.1 2.8 2 0 0 2 2 2 2 Mitochondrial carrier protein FAM176 PF14851.6 EGG13323.1 - 0.057 13.1 1.7 1.6 8.4 0.0 3.1 3 1 1 4 4 4 0 FAM176 family AAA_22 PF13401.6 EGG13324.1 - 1.7e-08 34.8 1.3 0.28 11.5 0.0 5.6 6 1 0 6 6 6 3 AAA domain AAA_7 PF12775.7 EGG13324.1 - 3.6e-08 33.1 4.1 0.025 14.1 0.0 4.8 4 1 0 4 4 4 3 P-loop containing dynein motor region AAA PF00004.29 EGG13324.1 - 1.9e-06 28.4 0.3 0.0052 17.2 0.0 4.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG13324.1 - 4.1e-05 24.0 0.0 0.068 13.5 0.0 3.8 3 1 0 3 3 3 2 AAA ATPase domain IstB_IS21 PF01695.17 EGG13324.1 - 0.025 14.3 0.0 0.82 9.4 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein T2SSE PF00437.20 EGG13324.1 - 0.06 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 EGG13324.1 - 0.2 11.8 0.0 3.1 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain PALP PF00291.25 EGG13325.1 - 2.8e-70 237.1 0.0 3.4e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 EGG13325.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein CH PF00307.31 EGG13326.1 - 1.3e-15 57.5 0.1 1.3e-15 57.5 0.1 2.9 3 0 0 3 3 3 1 Calponin homology (CH) domain GAS2 PF02187.17 EGG13326.1 - 2.2e-11 43.7 0.2 7.3e-11 42.0 0.2 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain SPX PF03105.19 EGG13326.1 - 2.6e-08 34.2 0.0 2.6e-08 34.2 0.0 7.5 2 2 1 3 3 3 1 SPX domain Choline_transpo PF04515.12 EGG13327.1 - 2e-102 342.7 35.5 2e-102 342.7 35.5 2.5 3 0 0 3 3 3 1 Plasma-membrane choline transporter YlaC PF10777.9 EGG13327.1 - 0.03 14.2 0.1 0.03 14.2 0.1 2.5 2 0 0 2 2 2 0 Inner membrane protein YlaC HbrB PF08539.11 EGG13327.1 - 0.19 11.7 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 HbrB-like ubiquitin PF00240.23 EGG13329.1 - 6.2e-152 493.6 24.1 1e-32 111.7 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 EGG13329.1 - 2.2e-70 232.5 22.2 7.4e-15 54.5 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGG13329.1 - 2.7e-24 85.4 12.6 0.00084 19.7 0.1 7.0 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 EGG13329.1 - 7.5e-18 64.2 4.4 0.07 13.1 0.0 5.2 4 1 1 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGG13329.1 - 8.3e-17 61.4 8.8 0.055 13.8 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGG13329.1 - 1.1e-16 60.9 2.0 0.26 11.4 0.0 5.8 5 3 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGG13329.1 - 1.6e-14 54.3 1.5 0.66 10.6 0.0 5.2 1 1 2 5 5 5 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.8 EGG13329.1 - 1.2e-07 32.0 0.0 36 4.8 0.0 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) Ubiquitin_4 PF18036.1 EGG13329.1 - 6.5e-07 29.3 25.0 31 4.7 0.0 8.9 9 0 0 9 9 9 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 EGG13329.1 - 8.6e-06 25.2 2.1 2.1 7.6 0.0 3.6 4 0 0 4 4 4 3 RNA methyltransferase Big_3_3 PF13750.6 EGG13329.1 - 3.4e-05 23.5 0.1 25 4.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) DUF969 PF06149.12 EGG13329.1 - 3.5e-05 23.3 0.1 23 4.3 0.0 4.8 4 1 1 5 5 5 0 Protein of unknown function (DUF969) DUF3861 PF12977.7 EGG13329.1 - 0.00015 21.9 1.3 38 4.5 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) ORF11CD3 PF10549.9 EGG13329.1 - 0.00021 21.3 0.6 1.1e+02 3.0 0.0 6.1 9 0 0 9 9 5 0 ORF11CD3 domain UDP-g_GGTase PF06427.11 EGG13329.1 - 0.00029 20.9 5.0 8.7 6.5 0.1 4.4 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF3435 PF11917.8 EGG13329.1 - 0.00069 18.7 0.5 26 3.6 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3435) Big_7 PF17957.1 EGG13329.1 - 0.0016 19.2 0.1 1.3e+02 3.4 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain ACT_5 PF13710.6 EGG13329.1 - 0.0025 17.6 3.3 51 3.8 0.0 4.3 4 0 0 4 4 4 0 ACT domain YcgR_2 PF12945.7 EGG13329.1 - 0.003 17.6 6.6 37 4.6 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR Corona_NS2A PF05213.12 EGG13329.1 - 0.0031 16.9 0.1 53 3.0 0.0 3.9 4 0 0 4 4 4 0 Coronavirus NS2A protein Imm12 PF15560.6 EGG13329.1 - 0.011 15.6 1.7 92 3.0 0.0 4.0 4 0 0 4 4 4 0 Immunity protein 12 ACT_4 PF13291.6 EGG13329.1 - 0.017 15.7 0.3 2.2e+02 2.5 0.0 4.2 4 0 0 4 4 4 0 ACT domain NEAT PF05031.12 EGG13329.1 - 0.067 13.8 5.1 62 4.2 2.8 3.9 2 1 1 3 3 3 0 Iron Transport-associated domain DMA PF03474.14 EGG13329.1 - 0.34 10.5 7.0 1.2e+02 2.4 0.0 5.0 5 0 0 5 5 5 0 DMRTA motif ProRS-C_2 PF09181.10 EGG13329.1 - 2.5 8.3 5.7 2.4e+02 2.0 0.1 3.9 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal PH_15 PF17339.2 EGG13329.1 - 3.7 7.5 6.6 76 3.3 0.1 3.7 4 1 0 4 4 4 0 PH domain MIP PF00230.20 EGG13330.1 - 3.7e-26 92.2 6.9 3.2e-25 89.2 6.9 1.9 1 1 0 1 1 1 1 Major intrinsic protein Dicty_spore_N PF04562.12 EGG13331.1 - 1.6e-21 77.1 24.5 1.6e-21 77.1 24.5 4.2 2 1 1 4 4 4 1 Dictyostelium spore coat protein, N terminus DAAD PF18752.1 EGG13334.1 - 3.4e-86 289.7 3.6 5e-86 289.2 2.8 1.6 2 0 0 2 2 2 1 Dictyosteliid AID/APOBEC-like Deaminase Meth_synt_2 PF01717.18 EGG13335.1 - 4.6e-05 22.9 0.0 0.00021 20.7 0.0 1.8 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Ank_3 PF13606.6 EGG13336.1 - 0.041 14.4 0.2 2.6 8.9 0.0 4.0 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 EGG13336.1 - 0.23 12.1 2.6 2.6 8.7 0.0 3.7 3 2 2 5 5 5 0 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EGG13336.1 - 0.33 11.0 0.0 0.33 11.0 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3447) APG6 PF04111.12 EGG13337.1 - 3.6e-41 141.1 1.9 1.1e-40 139.4 0.1 2.8 3 0 0 3 3 3 1 Apg6 BARA domain APG6_N PF17675.1 EGG13337.1 - 1.5e-05 25.5 1.3 1.5e-05 25.5 1.3 2.8 2 1 0 2 2 2 1 Apg6 coiled-coil region DUF829 PF05705.14 EGG13338.1 - 1.3e-33 116.9 0.4 8.6e-31 107.7 0.4 2.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) FUSC-like PF12805.7 EGG13341.1 - 0.22 10.5 0.1 0.37 9.8 0.1 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DDE_Tnp_1_7 PF13843.6 EGG13342.1 - 9.6e-29 100.8 0.1 9.6e-29 100.8 0.1 3.6 3 0 0 3 3 3 2 Transposase IS4 BSP_II PF05432.11 EGG13342.1 - 0.037 13.7 38.7 0.017 14.8 14.6 3.1 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) CCDC53 PF10152.9 EGG13342.1 - 0.11 12.9 22.7 0.87 10.0 0.6 3.4 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex DUF2052 PF09747.9 EGG13342.1 - 1.3 9.1 38.0 0.26 11.4 7.2 3.4 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Tim54 PF11711.8 EGG13342.1 - 3.8 6.2 26.5 0.09 11.5 1.3 3.3 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 NFACT-R_1 PF05670.13 EGG13343.1 - 1.4e-33 115.8 0.1 1.4e-33 115.8 0.1 3.8 4 0 0 4 4 4 1 NFACT protein RNA binding domain FbpA PF05833.11 EGG13343.1 - 1.2e-29 103.3 29.2 1.2e-29 103.3 29.2 3.9 3 2 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 EGG13343.1 - 4.3e-24 84.5 0.0 4.3e-24 84.5 0.0 6.0 6 1 2 8 8 8 1 NFACT protein C-terminal domain DUF3439 PF11921.8 EGG13343.1 - 1.5 8.8 13.4 1.4 8.9 3.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF5388 PF17363.2 EGG13344.1 - 0.061 13.5 0.1 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5388) adh_short PF00106.25 EGG13345.1 - 4.1e-42 143.9 0.0 6.2e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG13345.1 - 5.5e-23 81.7 0.0 8.1e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG13345.1 - 2.5e-12 47.1 0.1 9.7e-12 45.2 0.1 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG13345.1 - 0.024 14.1 0.1 0.24 10.8 0.1 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SBF PF01758.16 EGG13345.1 - 0.039 13.6 0.0 1.9 8.1 0.1 2.9 3 0 0 3 3 3 0 Sodium Bile acid symporter family F-box-like PF12937.7 EGG13345.1 - 0.12 12.3 0.1 0.31 11.0 0.1 1.8 1 1 0 1 1 1 0 F-box-like Peptidase_M8 PF01457.16 EGG13346.1 - 7.4e-40 137.1 0.1 3.3e-39 135.0 0.1 1.8 1 1 0 1 1 1 1 Leishmanolysin BRK PF07533.16 EGG13346.1 - 0.093 12.4 0.0 0.31 10.7 0.0 2.0 1 0 0 1 1 1 0 BRK domain Cys_rich_CWC PF14375.6 EGG13347.1 - 0.14 12.6 0.3 2.9 8.3 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich CWC Lactamase_B_6 PF16661.5 EGG13348.1 - 8.8e-16 57.9 1.9 1.6e-14 53.8 1.3 2.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EGG13348.1 - 8.2e-10 38.3 2.4 1.8e-07 30.7 1.9 2.9 2 1 0 2 2 2 2 Putative beta-lactamase-like family Peptidase_M24 PF00557.24 EGG13349.1 - 2.3e-27 96.1 0.1 4e-23 82.2 0.1 2.3 1 1 1 2 2 2 2 Metallopeptidase family M24 AMP_N PF05195.16 EGG13349.1 - 1.7e-23 82.7 0.0 5.9e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain CDC45 PF02724.14 EGG13349.1 - 0.017 13.4 18.8 0.023 13.0 18.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGG13349.1 - 0.076 11.2 23.7 0.1 10.8 23.7 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EGG13349.1 - 0.29 9.6 15.1 0.38 9.2 15.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 EGG13349.1 - 3.2 7.1 23.9 4.6 6.6 23.9 1.2 1 0 0 1 1 1 0 SDA1 Dicty_spore_N PF04562.12 EGG13350.1 - 4.5e-47 159.5 95.5 3e-24 85.9 19.3 4.9 5 0 0 5 5 5 3 Dictyostelium spore coat protein, N terminus Coa1 PF08695.10 EGG13351.1 - 5e-07 29.5 0.1 0.002 17.8 0.0 2.6 2 0 0 2 2 2 2 Cytochrome oxidase complex assembly protein 1 TIM21 PF08294.11 EGG13351.1 - 6e-05 23.0 0.1 0.00015 21.7 0.1 1.7 1 1 0 1 1 1 1 TIM21 LPD30 PF18850.1 EGG13352.1 - 0.062 13.1 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 Gp5_C PF06715.12 EGG13354.1 - 1.3 9.4 5.7 0.57 10.4 1.2 2.9 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) TfoX_C PF04994.13 EGG13355.1 - 7.9e-24 83.6 0.4 7.9e-24 83.6 0.4 2.0 2 0 0 2 2 2 1 TfoX C-terminal domain Cdd1 PF11731.8 EGG13355.1 - 0.00025 21.2 0.0 0.00049 20.3 0.0 1.5 1 0 0 1 1 1 1 Pathogenicity locus HHH_5 PF14520.6 EGG13355.1 - 0.025 15.2 0.1 0.05 14.2 0.1 1.6 1 1 0 1 1 1 0 Helix-hairpin-helix domain SLC12 PF03522.15 EGG13355.1 - 0.54 9.2 25.0 0.57 9.1 25.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2052 PF09747.9 EGG13355.1 - 0.98 9.5 30.8 1.4 9.0 30.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) ALMT PF11744.8 EGG13355.1 - 2.1 7.1 25.9 2.8 6.7 25.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Dapper PF15268.6 EGG13355.1 - 3 6.6 25.1 3.3 6.4 25.1 1.0 1 0 0 1 1 1 0 Dapper eIF-3c_N PF05470.12 EGG13355.1 - 3.4 5.9 29.8 3.7 5.8 29.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Menin PF05053.13 EGG13355.1 - 5.9 5.1 15.9 8.4 4.6 15.9 1.3 1 0 0 1 1 1 0 Menin Asp-B-Hydro_N PF05279.11 EGG13355.1 - 6 6.9 34.6 6.8 6.7 34.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region F-box-like PF12937.7 EGG13356.1 - 0.02 14.8 0.1 0.053 13.4 0.1 1.7 1 0 0 1 1 1 0 F-box-like AMP-binding PF00501.28 EGG13357.1 - 1e-56 192.4 0.0 1.5e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGG13357.1 - 8.2e-53 179.2 0.0 1.2e-52 178.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EGG13357.1 - 7.7e-08 32.6 0.4 1.6e-07 31.6 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EGG13357.1 - 2.5e-06 27.1 0.0 4.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG13357.1 - 0.0038 16.7 1.6 0.0082 15.6 0.1 2.3 3 1 0 3 3 3 1 GDP-mannose 4,6 dehydratase Glu_dehyd_C PF16912.5 EGG13357.1 - 0.027 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DUF3078 PF11276.8 EGG13357.1 - 2.5 8.6 7.2 0.87 10.1 1.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3078) 2OG-FeII_Oxy_3 PF13640.6 EGG13359.1 - 6.3e-09 36.6 0.1 1.4e-08 35.5 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EF-hand_like PF09279.11 EGG13359.1 - 0.02 15.3 0.3 0.071 13.6 0.3 1.9 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like DUF3837 PF12939.7 EGG13359.1 - 0.053 13.9 0.1 9 6.8 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) Tat PF00539.18 EGG13359.1 - 0.054 13.7 2.3 0.13 12.4 2.3 1.6 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) 2OG-FeII_Oxy_4 PF13661.6 EGG13359.1 - 0.1 13.3 0.1 0.25 12.0 0.1 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.7 EGG13360.1 - 0.089 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 F-box-like DUF374 PF04028.13 EGG13360.1 - 0.13 11.9 0.0 0.6 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Aerolysin PF01117.20 EGG13361.1 - 0.13 11.5 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Aerolysin toxin EF-hand_6 PF13405.6 EGG13362.1 - 1.4e-08 34.0 3.5 0.014 15.2 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 EGG13362.1 - 2.3e-07 29.9 3.3 0.023 14.2 0.1 3.9 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGG13362.1 - 3.6e-07 30.5 0.8 4.3e-05 23.9 0.5 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 EGG13362.1 - 0.00027 21.2 0.1 0.00064 20.0 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EGG13362.1 - 0.0013 18.6 4.0 0.0022 17.8 1.5 2.8 3 1 1 4 4 4 2 EF-hand domain pair Macoilin PF09726.9 EGG13362.1 - 1.1 7.8 14.2 1.9 7.0 14.2 1.5 1 0 0 1 1 1 0 Macoilin family BSP_II PF05432.11 EGG13362.1 - 1.7 8.2 21.7 2.9 7.5 21.7 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Zn-ribbon_8 PF09723.10 EGG13362.1 - 3.1 8.0 6.9 0.74 10.0 0.7 2.7 2 0 0 2 2 2 0 Zinc ribbon domain EF-hand_14 PF17959.1 EGG13362.1 - 6.9 7.1 9.0 2.4 8.5 0.1 3.4 3 1 0 3 3 3 0 EF-hand domain Tim54 PF11711.8 EGG13362.1 - 6.9 5.3 11.7 12 4.6 11.7 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PPL5 PF18168.1 EGG13362.1 - 7.9 5.7 9.9 19 4.4 9.9 1.7 1 0 0 1 1 1 0 Prim-pol family 5 Utp14 PF04615.13 EGG13363.1 - 0.0029 16.3 1.7 0.0039 15.9 1.7 1.0 1 0 0 1 1 1 1 Utp14 protein Mrpl_C PF18502.1 EGG13363.1 - 0.061 13.6 4.1 0.13 12.5 4.1 1.5 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain DUF4820 PF16091.5 EGG13364.1 - 0.046 13.1 1.9 0.11 11.9 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CPSF100_C PF13299.6 EGG13364.1 - 0.08 13.1 0.6 0.16 12.2 0.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 EGG13364.1 - 0.35 9.1 12.5 0.57 8.4 12.5 1.2 1 0 0 1 1 1 0 CDC45-like protein SspB PF04386.13 EGG13364.1 - 0.4 10.5 2.9 0.78 9.6 2.3 1.7 2 0 0 2 2 2 0 Stringent starvation protein B Astro_capsid_p PF12226.8 EGG13364.1 - 0.57 9.3 9.4 1.3 8.1 9.4 1.6 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Afi1 PF07792.12 EGG13364.1 - 0.66 10.5 15.9 2.6 8.6 8.7 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Sigma70_ner PF04546.13 EGG13364.1 - 1.4 8.7 11.6 0.074 12.9 5.6 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region TFB6 PF17110.5 EGG13364.1 - 2.2 8.0 7.8 6.1 6.5 7.8 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TRAP_alpha PF03896.16 EGG13364.1 - 3.3 6.9 12.3 0.1 11.8 6.1 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF2721 PF11026.8 EGG13365.1 - 0.02 14.8 3.8 0.03 14.2 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) Ca_hom_mod PF14798.6 EGG13365.1 - 0.03 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Calcium homeostasis modulator TMEM43 PF07787.12 EGG13365.1 - 0.041 13.3 0.3 0.041 13.3 0.3 2.4 2 1 1 3 3 3 0 Transmembrane protein 43 DUF3464 PF11947.8 EGG13365.1 - 0.24 11.1 1.4 0.32 10.7 0.0 1.9 2 1 0 2 2 2 0 Photosynthesis affected mutant 68 Mucin PF01456.17 EGG13365.1 - 0.27 11.2 8.4 0.31 11.0 1.7 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Acetyltransf_10 PF13673.7 EGG13366.1 - 9e-05 22.4 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG13366.1 - 0.0008 19.8 0.1 0.0012 19.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG13366.1 - 0.0013 19.0 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EGG13366.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase EGF_2 PF07974.13 EGG13367.1 - 8.6e-06 26.0 12.7 8.6e-06 26.0 12.7 2.1 2 0 0 2 2 2 1 EGF-like domain EGF_Tenascin PF18720.1 EGG13367.1 - 0.46 10.6 3.7 1.4 9.0 3.7 1.8 1 0 0 1 1 1 0 Tenascin EGF domain EGF PF00008.27 EGG13367.1 - 0.5 10.7 8.0 1.5 9.2 8.0 1.8 1 0 0 1 1 1 0 EGF-like domain 7tm_2 PF00002.24 EGG13368.1 - 1.9e-10 40.5 9.8 2.5e-10 40.1 9.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 EGG13368.1 - 5.1e-06 26.0 8.2 1.5e-05 24.4 4.5 2.8 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 EGG13368.1 - 0.00094 18.4 18.1 0.043 13.0 10.5 2.8 2 1 0 2 2 2 2 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 EGG13368.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.4 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Ocular_alb PF02101.15 EGG13368.1 - 1.9 7.3 16.3 0.99 8.3 0.9 3.3 2 2 1 3 3 3 0 Ocular albinism type 1 protein Response_reg PF00072.24 EGG13369.1 - 6.6e-13 48.8 0.0 1.5e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Fmp27_SW PF10305.9 EGG13369.1 - 0.049 14.3 1.7 0.2 12.4 0.2 2.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain LRR_4 PF12799.7 EGG13369.1 - 0.24 11.9 38.5 2.2 8.8 0.3 8.1 6 1 2 8 8 8 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGG13369.1 - 3 8.1 31.4 15 6.0 0.2 9.8 10 0 0 10 10 10 0 Leucine Rich repeat Secretin_N_2 PF07655.13 EGG13369.1 - 3.6 8.2 13.2 4.3 8.0 4.8 3.1 3 0 0 3 3 3 0 Secretin N-terminal domain F-box-like PF12937.7 EGG13370.1 - 0.0015 18.4 0.2 0.0044 16.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EGG13370.1 - 0.0024 17.8 26.2 0.035 14.2 0.3 7.9 8 0 0 8 8 8 2 Leucine Rich repeat Clat_adaptor_s PF01217.20 EGG13371.1 - 1.6e-20 73.5 4.1 2.3e-20 73.0 4.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.25 EGG13372.1 - 6.3e-53 179.8 1.0 6.3e-53 179.8 1.0 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13372.1 - 5e-23 81.7 7.3 1e-15 57.8 0.2 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EGG13372.1 - 7e-06 25.6 0.1 0.012 14.9 0.0 3.4 2 1 0 3 3 3 2 Kinase-like APH PF01636.23 EGG13372.1 - 0.014 15.4 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG13372.1 - 0.018 14.4 0.6 0.041 13.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_5_C PF18564.1 EGG13373.1 - 0.14 12.7 3.4 7.5 7.2 0.1 3.3 3 0 0 3 3 3 0 Glycoside hydrolase family 5 C-terminal domain Pkinase PF00069.25 EGG13374.1 - 1.2e-31 110.1 0.4 7.5e-31 107.4 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13374.1 - 9.2e-26 90.7 0.0 3.1e-25 88.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG13374.1 - 2.9e-05 23.1 0.1 6.9e-05 21.8 0.1 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGG13374.1 - 0.0018 17.7 0.0 0.0042 16.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGG13374.1 - 0.0078 16.2 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family AAA_22 PF13401.6 EGG13374.1 - 0.043 14.1 0.6 0.22 11.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain Tmemb_14 PF03647.13 EGG13375.1 - 7.6e-21 74.7 9.3 8.6e-21 74.5 9.3 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Phage_holin_3_3 PF16083.5 EGG13375.1 - 1.8 8.7 8.0 20 5.4 7.7 2.4 1 1 0 1 1 1 0 LydA holin phage, holin superfamily III FAD_binding_1 PF00667.20 EGG13376.1 - 1.1e-60 205.0 0.0 1.9e-60 204.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGG13376.1 - 9.3e-34 116.7 0.1 2.8e-33 115.1 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 EGG13376.1 - 9.6e-16 58.4 0.0 2.8e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Lipase_GDSL PF00657.22 EGG13376.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Dicty_REP PF05086.12 EGG13376.1 - 0.68 7.8 2.0 0.99 7.3 2.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein EB PF01683.18 EGG13377.1 - 0.0059 16.9 4.7 0.014 15.6 4.7 1.6 1 0 0 1 1 1 1 EB module LRR_4 PF12799.7 EGG13377.1 - 0.012 16.0 1.3 0.012 16.0 1.3 6.7 7 1 1 8 8 8 0 Leucine Rich repeats (2 copies) fn3 PF00041.21 EGG13377.1 - 0.13 12.7 0.8 18 5.7 0.1 2.7 2 0 0 2 2 2 0 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 EGG13377.1 - 0.55 10.9 4.3 24 5.6 0.1 3.2 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain EGF PF00008.27 EGG13377.1 - 1.6 9.1 9.8 3.5 8.0 9.8 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGG13377.1 - 3.5 8.4 9.1 8.6 7.2 9.1 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.13 EGG13377.1 - 5.2 7.5 14.4 12 6.4 14.4 1.6 1 0 0 1 1 1 0 EGF-like domain EB PF01683.18 EGG13379.1 - 0.0067 16.7 5.6 0.016 15.5 5.6 1.6 1 0 0 1 1 1 1 EB module LRR_8 PF13855.6 EGG13379.1 - 0.038 13.7 0.1 0.038 13.7 0.1 5.0 4 2 1 5 5 5 0 Leucine rich repeat DUF3844 PF12955.7 EGG13379.1 - 0.17 12.1 4.0 0.79 9.9 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) Recep_L_domain PF01030.24 EGG13379.1 - 0.46 10.6 7.0 41 4.3 0.3 4.9 3 1 1 4 4 4 0 Receptor L domain EGF PF00008.27 EGG13379.1 - 1.5 9.2 9.8 3.5 8.0 9.8 1.7 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGG13379.1 - 2.9 8.7 9.1 8.7 7.2 9.1 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF Oxysterol_BP PF01237.18 EGG13380.1 - 6.8e-67 225.9 4.8 1.1e-37 129.8 0.0 3.1 2 1 1 3 3 3 3 Oxysterol-binding protein Phage_tube PF04985.14 EGG13380.1 - 0.0019 17.9 0.1 0.01 15.5 0.0 2.1 2 0 0 2 2 2 1 Phage tail tube protein FII Tti2 PF10521.9 EGG13380.1 - 0.092 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Tti2 family Dicty_spore_N PF04562.12 EGG13381.1 - 2.3e-50 170.1 103.0 3.3e-23 82.6 21.5 5.3 4 0 0 4 4 4 3 Dictyostelium spore coat protein, N terminus AIRS_C PF02769.22 EGG13382.1 - 1.7e-26 93.3 0.0 2.4e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EGG13382.1 - 2.1e-06 28.3 0.0 5.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PRTP PF01366.18 EGG13383.1 - 0.0055 14.8 0.1 0.0065 14.6 0.1 1.0 1 0 0 1 1 1 1 Herpesvirus processing and transport protein Copine PF07002.16 EGG13384.1 - 1.5e-52 178.2 0.0 2.5e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGG13384.1 - 1.9e-17 63.4 0.1 2.5e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGG13384.1 - 0.00034 20.8 0.0 0.00056 20.1 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Glyco_hydro_7 PF00840.20 EGG13387.1 - 0.14 10.8 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 Ribosomal_L7Ae PF01248.26 EGG13388.1 - 1.7e-21 75.7 2.7 3.5e-21 74.7 2.7 1.5 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family EGF_2 PF07974.13 EGG13389.1 - 0.26 11.7 18.2 0.5 10.8 18.2 1.5 1 0 0 1 1 1 0 EGF-like domain Gal_mutarotas_2 PF13802.6 EGG13389.1 - 7.3 7.0 6.4 1.3 9.3 0.3 2.7 3 0 0 3 3 3 0 Galactose mutarotase-like PAH PF02671.21 EGG13393.1 - 7.4e-16 58.0 8.2 7.6e-09 35.6 0.4 2.9 3 0 0 3 3 3 2 Paired amphipathic helix repeat CCM2_C PF16545.5 EGG13393.1 - 0.0014 19.2 1.5 0.0068 16.9 0.3 2.2 1 1 1 2 2 2 1 Cerebral cavernous malformation protein, harmonin-homology YkyA PF10368.9 EGG13393.1 - 0.02 14.6 0.5 0.02 14.6 0.5 2.0 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Clr2_transil PF16761.5 EGG13393.1 - 0.11 13.3 0.1 0.29 12.0 0.1 1.7 1 0 0 1 1 1 0 Transcription-silencing protein, cryptic loci regulator Clr2 Yippee-Mis18 PF03226.14 EGG13394.1 - 1.1e-07 32.0 2.4 2.8e-07 30.7 2.4 1.7 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Eapp_C PF10238.9 EGG13394.1 - 2.1 8.4 6.1 4.2 7.4 1.9 2.9 1 1 1 2 2 2 0 E2F-associated phosphoprotein CaKB PF03185.15 EGG13396.1 - 0.014 15.0 1.0 0.019 14.6 1.0 1.2 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Collectrin PF16959.5 EGG13396.1 - 0.065 13.0 0.6 0.12 12.2 0.6 1.5 1 0 0 1 1 1 0 Renal amino acid transporter Vmethyltransf PF01660.17 EGG13397.1 - 0.047 12.6 0.9 0.082 11.8 0.9 1.3 1 0 0 1 1 1 0 Viral methyltransferase KASH PF10541.9 EGG13397.1 - 0.35 11.2 3.4 1.2 9.5 3.4 1.9 1 0 0 1 1 1 0 Nuclear envelope localisation domain p450 PF00067.22 EGG13398.1 - 8.8e-91 305.0 0.0 1.1e-90 304.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EGG13399.1 - 3.6e-16 59.3 2.2 8e-16 58.2 2.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13399.1 - 7.1e-10 38.6 0.1 1.1e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_16 PF13191.6 EGG13399.1 - 0.0066 16.9 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG13399.1 - 0.013 15.7 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGG13399.1 - 0.023 15.2 0.0 0.098 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EGG13399.1 - 0.031 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Pkinase PF00069.25 EGG13400.1 - 7.8e-20 71.3 0.5 1.6e-19 70.3 0.5 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13400.1 - 6.8e-12 45.2 0.2 1.2e-11 44.5 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGG13400.1 - 0.00022 20.7 0.1 0.00038 19.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGG13400.1 - 0.0029 17.2 0.1 0.0059 16.2 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase ResIII PF04851.15 EGG13400.1 - 0.0057 16.7 0.1 0.014 15.4 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EGG13400.1 - 0.013 14.9 0.1 0.034 13.6 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 EGG13400.1 - 0.03 13.7 0.2 0.096 12.0 0.0 1.8 2 0 0 2 2 2 0 KaiC APH PF01636.23 EGG13400.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family ABC_tran PF00005.27 EGG13400.1 - 0.18 12.3 1.2 2.5 8.6 1.2 2.6 1 1 0 1 1 1 0 ABC transporter Ank_2 PF12796.7 EGG13401.1 - 8.2e-05 23.1 1.0 0.052 14.2 0.1 4.1 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG13401.1 - 0.15 12.7 1.7 64 4.6 0.0 4.7 3 0 0 3 3 3 0 Ankyrin repeat CPSF100_C PF13299.6 EGG13401.1 - 2.1 8.5 8.4 5.3 7.2 0.0 2.5 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal PBP_sp32 PF07222.12 EGG13401.1 - 2.5 7.5 7.6 5 6.5 7.6 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Peptidase_M66 PF10462.9 EGG13402.1 - 5.1e-84 281.8 0.2 7.6e-84 281.3 0.2 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 EGG13402.1 - 0.0018 18.8 0.3 0.0043 17.6 0.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EGG13402.1 - 0.033 13.8 0.6 0.068 12.8 0.6 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 EGG13402.1 - 0.13 10.8 0.8 0.2 10.2 0.8 1.2 1 0 0 1 1 1 0 Putative peptidase family SET PF00856.28 EGG13403.1 - 2.6e-10 41.0 0.0 6.6e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 SET domain DASH_Dad3 PF08656.10 EGG13404.1 - 0.017 15.2 0.2 0.028 14.5 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad3 Abhydrolase_1 PF00561.20 EGG13405.1 - 2.5e-10 40.5 0.1 2e-08 34.2 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.14 EGG13405.1 - 0.0014 17.4 0.0 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 EGG13405.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 BSP_II PF05432.11 EGG13405.1 - 0.2 11.3 22.2 0.29 10.8 22.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 EGG13405.1 - 1.2 7.4 7.9 1.6 6.9 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Barttin PF15462.6 EGG13405.1 - 2 8.1 6.3 3.3 7.4 6.3 1.2 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) PI3K_1B_p101 PF10486.9 EGG13405.1 - 8.1 4.1 7.0 11 3.7 7.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FNIP PF05725.12 EGG13406.1 - 5.8e-17 61.6 15.8 9.6e-07 28.9 0.6 5.4 3 2 1 5 5 5 3 FNIP Repeat DUF3844 PF12955.7 EGG13407.1 - 0.018 15.2 7.7 1.1 9.5 2.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) TIG PF01833.24 EGG13407.1 - 1.1 9.3 17.2 0.12 12.4 1.6 4.6 4 0 0 4 4 4 0 IPT/TIG domain EGF_2 PF07974.13 EGG13407.1 - 6.9 7.1 27.9 0.05 14.0 12.1 2.9 3 0 0 3 3 3 0 EGF-like domain Gelsolin PF00626.22 EGG13408.1 - 1.1e-46 156.5 0.0 5e-16 58.4 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat ketoacyl-synt PF00109.26 EGG13409.1 - 7.4e-62 209.2 0.0 1.3e-61 208.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG13409.1 - 4.5e-51 174.2 0.0 7.5e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGG13409.1 - 4.1e-35 120.3 0.1 2e-34 118.1 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGG13409.1 - 8.4e-28 97.5 2.6 2.4e-27 96.0 0.1 2.8 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 EGG13409.1 - 9.2e-28 97.3 0.0 1.4e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGG13409.1 - 6.4e-17 62.0 0.4 2.7e-16 60.0 0.4 2.2 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGG13409.1 - 2e-09 38.6 0.0 2e-07 32.1 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG13409.1 - 5.4e-06 26.3 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGG13409.1 - 1.7e-05 25.1 0.0 5.9e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGG13409.1 - 0.00043 19.7 0.1 0.0014 18.1 0.1 1.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain Ist1 PF03398.14 EGG13410.1 - 4e-50 169.9 5.3 5.1e-50 169.6 5.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Pkinase PF00069.25 EGG13411.1 - 8.3e-27 94.2 0.6 8.3e-27 94.2 0.6 3.4 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13411.1 - 9.7e-24 84.0 0.4 1.3e-12 47.6 0.3 3.1 2 0 0 2 2 2 2 Protein tyrosine kinase TPR_12 PF13424.6 EGG13411.1 - 6.2e-18 64.9 9.4 9.1e-12 45.1 3.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGG13411.1 - 4.9e-07 29.3 23.6 6.2e-05 22.6 0.3 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGG13411.1 - 8.3e-05 23.0 6.8 1.2 9.9 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG13411.1 - 0.00012 21.9 12.7 0.0023 17.9 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGG13411.1 - 0.00023 20.9 11.7 0.024 14.5 0.2 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG13411.1 - 0.0058 16.7 18.4 0.013 15.7 0.2 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat MIT PF04212.18 EGG13411.1 - 0.0096 16.0 8.9 4.5 7.4 0.8 4.7 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain NB-ARC PF00931.22 EGG13411.1 - 0.0099 15.1 0.0 0.053 12.7 0.0 2.3 1 1 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 EGG13411.1 - 0.084 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain TPR_19 PF14559.6 EGG13411.1 - 0.12 12.9 0.6 0.94 10.0 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat AAA_18 PF13238.6 EGG13411.1 - 0.37 11.3 1.9 4.2 7.9 0.0 3.2 2 0 0 2 2 2 0 AAA domain TPR_7 PF13176.6 EGG13411.1 - 0.41 10.8 5.5 52 4.2 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_11 PF13086.6 EGG13411.1 - 0.82 9.4 0.0 0.82 9.4 0.0 3.9 4 0 0 4 4 4 0 AAA domain Pkinase PF00069.25 EGG13413.1 - 9.6e-45 153.0 1.3 1.6e-44 152.3 1.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13413.1 - 1.1e-35 123.2 0.3 1.8e-35 122.5 0.3 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EGG13413.1 - 0.0015 18.2 4.2 0.019 14.6 0.1 2.8 2 1 1 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 DUF815 PF05673.13 EGG13413.1 - 0.006 15.8 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Kdo PF06293.14 EGG13413.1 - 0.0067 15.8 0.1 0.014 14.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ATPase PF06745.13 EGG13413.1 - 0.013 14.9 0.2 0.031 13.6 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 EGG13413.1 - 0.018 15.1 6.9 0.33 11.0 0.0 3.8 4 0 0 4 4 4 0 AAA domain TRIQK PF15168.6 EGG13413.1 - 0.019 14.9 0.4 0.35 10.8 0.1 2.5 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DAP3 PF10236.9 EGG13413.1 - 0.036 13.2 0.5 27 3.8 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 APH PF01636.23 EGG13413.1 - 0.038 13.9 0.1 1.8 8.4 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family AAA_16 PF13191.6 EGG13413.1 - 0.084 13.3 0.0 6.7 7.1 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain IMUP PF15761.5 EGG13414.1 - 0.016 15.9 1.6 0.028 15.1 1.6 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein SRC-1 PF08832.10 EGG13414.1 - 0.12 13.5 0.4 0.37 11.9 0.4 1.8 1 0 0 1 1 1 0 Steroid receptor coactivator RasGEF PF00617.19 EGG13415.1 - 9.6e-49 166.0 0.1 3.3e-48 164.2 0.1 2.0 1 0 0 1 1 1 1 RasGEF domain RhoGAP PF00620.27 EGG13415.1 - 8.5e-12 45.1 0.8 8.5e-12 45.1 0.8 3.2 3 1 0 3 3 3 1 RhoGAP domain RasGEF_N PF00618.20 EGG13415.1 - 3.5e-09 36.8 1.3 3.5e-09 36.8 1.3 4.5 3 0 0 3 3 3 1 RasGEF N-terminal motif FH2 PF02181.23 EGG13416.1 - 5.1e-83 279.3 12.4 5.1e-83 279.3 12.4 3.0 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 EGG13416.1 - 2.7e-27 95.7 0.8 1.2e-26 93.6 0.8 2.1 1 0 0 1 1 1 1 Diaphanous FH3 Domain DUF1664 PF07889.12 EGG13416.1 - 0.45 10.6 8.2 1.2 9.2 1.4 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF4179 PF13786.6 EGG13419.1 - 1.9 9.0 7.9 7.2 7.2 1.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Hormone_5 PF00184.17 EGG13419.1 - 2.7 8.9 15.7 3.9 8.4 2.2 2.9 3 0 0 3 3 3 0 Neurohypophysial hormones, C-terminal Domain EGF_2 PF07974.13 EGG13419.1 - 6.6 7.2 43.1 0.046 14.1 12.1 2.9 3 0 0 3 3 3 0 EGF-like domain EGF_2 PF07974.13 EGG13420.1 - 0.011 16.1 12.8 0.011 16.1 12.8 2.8 3 0 0 3 3 3 0 EGF-like domain EGF PF00008.27 EGG13420.1 - 0.11 12.9 20.5 0.066 13.5 11.3 2.6 2 0 0 2 2 2 0 EGF-like domain AI-2E_transport PF01594.16 EGG13420.1 - 0.42 9.7 3.1 0.93 8.6 3.1 1.5 1 0 0 1 1 1 0 AI-2E family transporter Actin_micro PF17003.5 EGG13422.1 - 0.00028 20.2 4.9 0.00028 20.2 4.9 1.5 1 1 0 1 1 1 1 Putative actin-like family zf-C2H2_jaz PF12171.8 EGG13422.1 - 0.0017 18.6 3.8 0.0017 18.6 3.8 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Orf78 PF06024.12 EGG13422.1 - 0.0046 17.2 1.4 0.038 14.3 0.0 2.3 2 0 0 2 2 2 1 Orf78 (ac78) TRAP_beta PF05753.14 EGG13422.1 - 0.0056 16.1 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) zf-C2H2_4 PF13894.6 EGG13422.1 - 0.0074 17.0 3.5 0.027 15.3 1.3 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 EGG13422.1 - 0.013 15.9 0.9 0.013 15.9 0.9 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ARS2 PF04959.13 EGG13422.1 - 0.024 15.0 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 Arsenite-resistance protein 2 zf-C2H2_6 PF13912.6 EGG13422.1 - 0.024 14.6 1.0 0.024 14.6 1.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGG13422.1 - 0.29 11.7 4.2 0.34 11.4 1.9 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type NAD_binding_6 PF08030.12 EGG13423.1 - 4.5e-32 111.3 0.0 6.7e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGG13423.1 - 1.1e-20 74.0 13.3 3e-20 72.6 13.3 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGG13423.1 - 1.5e-19 70.1 0.0 5.7e-18 65.0 0.0 2.3 2 0 0 2 2 2 1 FAD-binding domain FAD_binding_6 PF00970.24 EGG13423.1 - 0.00056 20.2 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGG13423.1 - 0.029 15.0 0.0 0.15 12.7 0.0 2.1 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain HSP20 PF00011.21 EGG13424.1 - 6.9e-13 48.6 0.1 4.4e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG13424.1 - 3.1e-05 23.4 0.0 0.028 14.0 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA DUF1387 PF07139.11 EGG13424.1 - 3.1 7.5 8.1 4 7.1 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Nucleoporin_FG PF13634.6 EGG13425.1 - 1.4e-19 70.7 300.6 5.1e-07 30.4 21.4 14.4 3 3 8 12 12 12 8 Nucleoporin FG repeat region ANAPC4_WD40 PF12894.7 EGG13425.1 - 0.004 17.4 0.1 0.012 15.9 0.1 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain MCPsignal PF00015.21 EGG13425.1 - 1.3 8.8 5.6 0.25 11.2 1.6 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain EF-hand_1 PF00036.32 EGG13427.1 - 2.9e-12 45.2 0.1 6.2e-07 28.5 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGG13427.1 - 3.2e-11 42.9 0.3 2.7e-07 30.3 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EGG13427.1 - 2e-10 40.9 0.0 2.3e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGG13427.1 - 4.5e-10 38.6 0.1 2.7e-07 30.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.6 EGG13427.1 - 1e-06 29.0 0.0 1.2e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EFhand_Ca_insen PF08726.10 EGG13427.1 - 0.0015 18.6 0.1 0.0038 17.3 0.1 1.7 1 1 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 EGG13427.1 - 0.0044 16.4 0.0 0.013 15.0 0.0 1.9 2 1 0 2 2 2 1 EF hand DDE_Tnp_IS66_C PF13817.6 EGG13427.1 - 0.0096 16.1 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 IS66 C-terminal element RabGAP-TBC PF00566.18 EGG13429.1 - 2.5e-45 154.8 4.2 2.5e-45 154.8 4.2 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF962 PF06127.11 EGG13430.1 - 2.4e-16 59.6 2.2 1.1e-15 57.5 2.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Yip1 PF04893.17 EGG13430.1 - 2.5 7.8 12.7 0.31 10.7 7.5 2.1 1 1 0 1 1 1 0 Yip1 domain HlyIII PF03006.20 EGG13432.1 - 6.3e-42 143.8 24.3 1.2e-41 142.9 24.3 1.5 1 0 0 1 1 1 1 Haemolysin-III related DUF1768 PF08719.11 EGG13432.1 - 5.6e-34 117.7 0.0 5.6e-34 117.7 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1768) SPT6_acidic PF14632.6 EGG13434.1 - 0.037 14.6 3.8 0.082 13.5 3.8 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Cas_Csd1 PF09709.10 EGG13435.1 - 0.071 11.8 1.0 3.6 6.2 0.4 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csd1) Glyco_hydro_20 PF00728.22 EGG13436.1 - 0.098 12.0 2.9 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, catalytic domain Apt1 PF10351.9 EGG13437.1 - 7.6e-05 21.7 1.1 8.8e-05 21.5 1.1 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Med13_C PF06333.12 EGG13437.1 - 0.0058 16.0 1.8 0.0078 15.5 1.8 1.1 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain SR-25 PF10500.9 EGG13437.1 - 0.0059 16.3 7.1 0.0089 15.7 7.1 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Mucin PF01456.17 EGG13437.1 - 0.18 11.8 17.6 0.77 9.7 18.2 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein O-antigen_lig PF13425.6 EGG13437.1 - 0.22 10.2 5.1 0.31 9.8 5.1 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3439 PF11921.8 EGG13437.1 - 0.35 10.8 9.9 0.74 9.8 9.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SR-25 PF10500.9 EGG13438.1 - 2.6e-05 24.0 4.8 3.6e-05 23.5 4.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Mucin PF01456.17 EGG13438.1 - 0.014 15.4 10.4 0.1 12.6 10.8 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Med13_C PF06333.12 EGG13438.1 - 0.087 12.1 3.0 0.16 11.2 3.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain IMUP PF15761.5 EGG13438.1 - 1 10.1 7.4 1.8 9.3 7.4 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF4710 PF15828.5 EGG13439.1 - 0.014 15.5 4.3 0.014 15.5 4.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) eIF3_p135 PF12807.7 EGG13439.1 - 0.027 14.5 7.9 0.59 10.1 2.5 2.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 Ish1 PF10281.9 EGG13439.1 - 0.12 12.7 5.0 3.1 8.2 0.1 4.0 4 0 0 4 4 4 0 Putative stress-responsive nuclear envelope protein H-kinase_dim PF02895.14 EGG13439.1 - 1.1 9.7 4.0 15 6.1 0.3 2.8 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain CCDC106 PF15794.5 EGG13439.1 - 1.2 8.7 16.9 0.11 12.2 8.7 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Connexin PF00029.19 EGG13439.1 - 1.8 8.3 9.4 0.16 11.7 2.1 2.3 2 0 0 2 2 2 0 Connexin Peptidase_S49_N PF08496.10 EGG13439.1 - 3.4 7.7 21.2 0.12 12.4 7.6 2.8 3 0 0 3 3 3 0 Peptidase family S49 N-terminal SR-25 PF10500.9 EGG13441.1 - 0.0011 18.6 6.0 0.0016 18.1 6.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SRP72 PF08492.12 EGG13441.1 - 0.15 12.5 5.9 0.33 11.4 5.9 1.5 1 0 0 1 1 1 0 SRP72 RNA-binding domain GET2 PF08690.10 EGG13441.1 - 0.16 11.6 3.5 0.25 11.0 3.5 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Med3 PF11593.8 EGG13441.1 - 6.7 5.8 11.1 11 5.1 11.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SR-25 PF10500.9 EGG13443.1 - 0.002 17.8 7.2 0.0024 17.5 7.2 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AP3D1 PF06375.11 EGG13443.1 - 0.027 14.7 3.7 0.03 14.6 3.7 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Med3 PF11593.8 EGG13443.1 - 0.1 11.7 12.4 0.12 11.5 12.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NKAP PF15692.5 EGG13443.1 - 0.13 13.0 8.3 0.15 12.8 8.3 1.1 1 0 0 1 1 1 0 NF-kappa-B-activating protein Coilin_N PF15862.5 EGG13443.1 - 0.28 11.0 5.6 0.32 10.8 5.6 1.1 1 0 0 1 1 1 0 Coilin N-terminus Dicty_REP PF05086.12 EGG13443.1 - 0.36 8.8 9.6 0.34 8.8 9.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 EGG13443.1 - 0.65 10.0 15.2 0.69 9.9 15.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein TSGP1 PF07771.11 EGG13443.1 - 1.3 9.2 10.3 2.3 8.4 10.3 1.4 1 1 0 1 1 1 0 Tick salivary peptide group 1 DUF4710 PF15828.5 EGG13443.1 - 1.9 8.7 13.9 2.1 8.6 13.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4710) SSP160 PF06933.11 EGG13443.1 - 1.9 6.6 10.3 1.9 6.6 10.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TMEM154 PF15102.6 EGG13443.1 - 6.7 6.6 9.0 8.7 6.2 9.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family RNA_polI_A34 PF08208.11 EGG13444.1 - 0.37 10.9 10.6 0.32 11.0 9.0 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 CCDC106 PF15794.5 EGG13444.1 - 1.7 8.3 11.4 0.048 13.4 5.3 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 NKAP PF15692.5 EGG13444.1 - 5 7.9 9.4 2.3 9.0 5.6 2.1 2 0 0 2 2 2 0 NF-kappa-B-activating protein Dicty_REP PF05086.12 EGG13444.1 - 6.5 4.6 27.4 1.9 6.4 12.7 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Ish1 PF10281.9 EGG13445.1 - 0.022 15.0 0.0 0.77 10.1 0.0 2.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein DUF4834 PF16118.5 EGG13446.1 - 0.00031 21.7 6.5 0.0019 19.1 0.0 2.5 1 1 0 2 2 2 1 Domain of unknown function (DUF4834) TMEM151 PF14857.6 EGG13446.1 - 0.0084 15.1 0.1 0.016 14.1 0.1 1.4 1 0 0 1 1 1 1 TMEM151 family Presenilin PF01080.17 EGG13446.1 - 0.079 11.7 4.5 0.13 10.9 4.5 1.4 1 0 0 1 1 1 0 Presenilin OAD_gamma PF04277.13 EGG13446.1 - 0.15 12.6 1.8 0.47 11.1 0.7 2.6 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Utp14 PF04615.13 EGG13446.1 - 0.34 9.4 16.1 0.44 9.1 16.1 1.1 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.14 EGG13446.1 - 0.48 8.6 13.4 0.73 8.1 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3439 PF11921.8 EGG13446.1 - 0.79 9.7 7.7 1.8 8.5 7.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Nop14 PF04147.12 EGG13446.1 - 1.9 6.6 16.3 2.6 6.1 16.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EGG13446.1 - 2.8 5.9 10.2 4.1 5.4 10.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi CAC1F_C PF16885.5 EGG13446.1 - 4.6 6.8 9.2 6.9 6.2 9.2 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Roughex PF06020.11 EGG13446.1 - 4.9 6.1 11.0 7.1 5.6 11.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PI3K_1B_p101 PF10486.9 EGG13446.1 - 7.6 4.2 8.6 11 3.7 8.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GREB1 PF15782.5 EGG13446.1 - 8.4 3.4 9.5 11 3.0 9.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SR-25 PF10500.9 EGG13448.1 - 3.5 7.2 15.8 3.7 7.1 6.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1824 PF08854.10 EGG13449.1 - 0.0025 17.7 1.0 0.47 10.4 0.1 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1824) Recombinase PF07508.13 EGG13449.1 - 0.04 14.3 0.4 0.13 12.7 0.2 2.0 2 0 0 2 2 2 0 Recombinase Orthopox_F8 PF05886.11 EGG13451.1 - 0.042 14.0 2.2 0.062 13.4 0.3 2.3 2 0 0 2 2 2 0 Orthopoxvirus F8 protein SPT6_acidic PF14632.6 EGG13451.1 - 0.44 11.2 6.7 1.1 9.9 2.1 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 SR-25 PF10500.9 EGG13451.1 - 0.97 9.0 17.3 0.089 12.4 1.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein LRR_5 PF13306.6 EGG13452.1 - 0.0075 16.2 6.9 0.88 9.5 0.1 4.1 2 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 EGG13452.1 - 0.025 14.7 0.9 0.025 14.7 0.9 6.7 5 2 1 6 6 6 0 FNIP Repeat Dicty_REP PF05086.12 EGG13453.1 - 0.042 11.8 7.7 0.051 11.6 7.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ish1 PF10281.9 EGG13454.1 - 0.16 12.3 1.0 27 5.2 0.0 3.5 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein Rad60-SLD PF11976.8 EGG13455.1 - 1.5e-11 44.0 6.2 5.7e-06 26.1 0.1 4.4 4 0 0 4 4 4 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGG13455.1 - 0.011 15.4 0.0 0.26 11.1 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin family COX2 PF00116.20 EGG13456.1 - 0.009 15.9 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain DIM1 PF02966.16 EGG13457.1 - 3.4e-65 217.8 0.1 3.9e-65 217.6 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EGG13457.1 - 0.0012 18.7 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Cast PF10174.9 EGG13457.1 - 0.037 12.3 0.2 0.048 11.9 0.2 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Thioredoxin_8 PF13905.6 EGG13457.1 - 0.045 14.1 0.2 0.074 13.4 0.2 1.4 1 1 0 1 1 1 0 Thioredoxin-like DUF3192 PF11399.8 EGG13457.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) RasGEF PF00617.19 EGG13458.1 - 4e-55 186.7 1.5 1.6e-54 184.8 1.5 2.1 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGG13458.1 - 1.4e-16 60.6 7.0 5.4e-10 39.4 0.8 3.5 3 0 0 3 3 3 2 RasGEF N-terminal motif DEP PF00610.21 EGG13458.1 - 8.7e-15 54.6 0.1 1.6e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Methyltransf_21 PF05050.12 EGG13458.1 - 1.4 8.9 4.0 1.2 9.2 1.4 2.3 2 1 0 2 2 2 0 Methyltransferase FkbM domain DUF5559 PF17714.1 EGG13458.1 - 6.8 6.5 8.0 2.2 8.1 4.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5559) Toxin_27 PF08099.11 EGG13459.1 - 0.34 11.0 0.3 0.34 11.0 0.3 1.9 2 0 0 2 2 2 0 Scorpion calcine family CLU PF13236.6 EGG13462.1 - 4e-07 30.1 0.2 8e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 Clustered mitochondria LRR_2 PF07723.13 EGG13462.1 - 0.051 14.3 0.0 7.3 7.4 0.0 3.5 2 0 0 2 2 2 0 Leucine Rich Repeat DUF3439 PF11921.8 EGG13462.1 - 0.066 13.2 13.7 0.53 10.3 3.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) eIF3_p135 PF12807.7 EGG13462.1 - 1 9.3 9.6 0.56 10.2 0.4 3.4 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit 135 DUF2098 PF09871.9 EGG13463.1 - 0.36 11.2 2.8 0.29 11.5 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) BTB_2 PF02214.22 EGG13464.1 - 3.3e-12 46.6 0.0 6.2e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 EGG13465.1 - 1.5e-34 117.8 18.3 5.4e-09 35.9 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 EGG13465.1 - 1.8e-27 95.0 16.2 1.2e-08 35.0 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 EGG13465.1 - 4.9e-27 93.2 14.8 5.6e-07 29.0 0.4 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EGG13465.1 - 1.1e-25 89.1 15.5 4e-07 29.9 0.4 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EGG13465.1 - 9.6e-23 79.7 13.2 4.8e-06 26.7 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGG13465.1 - 2.1e-13 49.6 5.8 0.13 12.3 0.1 5.5 5 0 0 5 5 5 5 Kelch motif Band_7 PF01145.25 EGG13466.1 - 3.2e-33 115.2 3.9 5e-33 114.6 3.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EGG13466.1 - 0.068 12.9 0.5 0.11 12.1 0.5 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family OEP PF02321.18 EGG13466.1 - 2.4 7.9 5.8 1.6 8.5 0.6 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein WH1 PF00568.23 EGG13467.1 - 3.6e-21 75.2 0.1 5.2e-21 74.7 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 EGG13467.1 - 1.8e-09 37.1 0.5 1.8e-09 37.1 0.5 2.0 2 0 0 2 2 2 1 WH2 motif VASP_tetra PF08776.11 EGG13467.1 - 4.2e-05 23.0 3.1 6.8e-05 22.4 3.1 1.3 1 0 0 1 1 1 1 VASP tetramerisation domain Ran_BP1 PF00638.18 EGG13467.1 - 0.0052 17.0 0.0 0.015 15.5 0.0 1.7 1 1 0 1 1 1 1 RanBP1 domain Peptidase_C48 PF02902.19 EGG13468.1 - 4.6e-34 118.2 2.8 4.6e-34 118.2 2.8 2.2 2 1 1 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain PIF1 PF05970.14 EGG13469.1 - 1.2e-57 195.8 0.5 3e-42 145.1 0.0 2.7 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EGG13469.1 - 1.3e-16 60.9 0.0 2.6e-15 56.6 0.0 2.7 1 1 0 1 1 1 1 AAA domain ORC3_N PF07034.11 EGG13469.1 - 1.4e-14 54.0 1.0 1.4e-14 54.0 1.0 2.3 3 0 0 3 3 2 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 EGG13469.1 - 3.3e-13 49.9 0.1 2e-09 37.7 0.0 5.2 4 3 1 5 5 2 2 Origin recognition complex winged helix C-terminal AAA_19 PF13245.6 EGG13469.1 - 4.1e-10 40.2 0.0 1.6e-09 38.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGG13469.1 - 3.2e-06 27.6 0.0 8.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGG13469.1 - 0.00038 20.2 0.1 0.00038 20.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain BUD22 PF09073.10 EGG13469.1 - 0.00066 19.1 14.9 0.00066 19.1 14.9 4.8 4 1 0 5 5 4 1 BUD22 AAA_7 PF12775.7 EGG13469.1 - 0.00086 18.9 0.3 0.00086 18.9 0.3 2.3 2 0 0 2 2 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EGG13469.1 - 0.0012 19.2 0.0 0.0059 16.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGG13469.1 - 0.0016 18.5 0.0 0.013 15.5 0.0 2.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGG13469.1 - 0.0029 17.4 0.1 0.0094 15.7 0.1 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase_2 PF01637.18 EGG13469.1 - 0.0056 16.6 0.1 0.0056 16.6 0.1 3.5 4 0 0 4 4 3 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 EGG13469.1 - 0.006 15.7 0.3 0.015 14.4 0.3 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 EGG13469.1 - 0.0097 16.3 0.0 0.03 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EGG13469.1 - 0.012 16.2 0.1 0.012 16.2 0.1 3.5 3 0 0 3 3 2 0 ABC transporter NTPase_1 PF03266.15 EGG13469.1 - 0.019 14.9 0.4 0.67 9.9 0.4 2.6 2 0 0 2 2 2 0 NTPase UvrD_C_2 PF13538.6 EGG13469.1 - 0.033 14.0 0.1 0.091 12.6 0.0 1.8 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain MMR_HSR1 PF01926.23 EGG13469.1 - 0.073 13.2 0.1 0.073 13.2 0.1 2.7 2 0 0 2 2 1 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 EGG13469.1 - 0.095 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 EGG13469.1 - 0.12 12.2 0.1 0.12 12.2 0.1 5.4 5 1 0 5 5 4 0 AAA domain Helicase_RecD PF05127.14 EGG13469.1 - 0.35 10.7 0.0 0.35 10.7 0.0 3.1 3 0 0 3 3 2 0 Helicase ATG27 PF09451.10 EGG13470.1 - 0.063 13.1 0.1 0.075 12.9 0.1 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 RabGAP-TBC PF00566.18 EGG13472.1 - 1.2e-55 188.5 1.5 1.2e-55 188.5 1.5 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 EGG13472.1 - 1.6e-54 182.4 6.7 4.8e-14 52.7 0.0 5.9 4 2 2 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.30 EGG13472.1 - 1.3e-49 164.5 13.9 2.9e-07 30.6 0.1 9.9 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 EGG13472.1 - 5.3e-46 154.4 20.4 7.4e-11 42.4 0.1 8.0 3 1 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG13472.1 - 1.8e-39 129.2 3.9 0.002 18.4 0.0 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 EGG13472.1 - 1e-32 111.7 14.2 7.9e-08 32.4 0.1 7.4 3 2 5 8 8 8 7 Ankyrin repeats (many copies) DUF4133 PF13571.6 EGG13472.1 - 0.11 12.8 0.5 0.35 11.2 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) COG5 PF10392.9 EGG13474.1 - 9.1e-23 80.9 6.1 9.1e-23 80.9 6.1 4.4 4 1 1 5 5 5 1 Golgi transport complex subunit 5 COG2 PF06148.11 EGG13474.1 - 4.5e-11 43.0 5.2 4.5e-11 43.0 5.2 3.0 2 1 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EGG13474.1 - 1.6e-05 24.9 3.3 1.6e-05 24.9 3.3 2.8 2 0 0 2 2 2 1 Vps51/Vps67 BLOC1_2 PF10046.9 EGG13474.1 - 0.79 10.1 20.5 0.053 13.8 3.4 4.1 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_N PF02465.18 EGG13474.1 - 1 10.1 12.7 0.13 13.0 3.6 3.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Sec3_C_2 PF15278.6 EGG13474.1 - 2.1 8.8 11.7 0.045 14.1 1.3 3.3 2 1 1 3 3 3 0 Sec3 exocyst complex subunit Cytochrom_B562 PF07361.11 EGG13474.1 - 4.5 8.0 14.0 1.2 9.8 0.5 3.4 3 1 1 4 4 4 0 Cytochrome b562 TAFII55_N PF04658.13 EGG13475.1 - 6.3e-39 133.3 3.6 1.2e-38 132.3 0.3 2.3 2 0 0 2 2 2 1 TAFII55 protein conserved region DUF3228 PF11539.8 EGG13475.1 - 0.019 14.5 0.4 0.038 13.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) HAUS6_N PF14661.6 EGG13475.1 - 0.13 11.9 0.6 0.23 11.0 0.6 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Cytochrom_B562 PF07361.11 EGG13475.1 - 0.22 12.2 4.8 0.25 12.0 2.5 2.2 2 0 0 2 2 2 0 Cytochrome b562 DUF1664 PF07889.12 EGG13475.1 - 0.87 9.6 3.9 1.7 8.7 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Lzipper-MIP1 PF14389.6 EGG13475.1 - 1 9.7 6.4 7.5 6.9 3.1 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Fib_alpha PF08702.10 EGG13475.1 - 4 7.6 9.5 3.4 7.8 5.7 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TPR_2 PF07719.17 EGG13476.1 - 6.8e-10 38.3 8.6 0.031 14.4 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGG13476.1 - 1e-07 31.4 13.2 0.0079 16.0 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat Spt20 PF12090.8 EGG13476.1 - 2.6e-05 23.9 17.7 2.6e-05 23.9 17.7 5.6 4 2 0 4 4 4 1 Spt20 family TPR_12 PF13424.6 EGG13476.1 - 0.0016 18.7 8.8 23 5.4 0.9 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGG13476.1 - 0.0025 18.3 8.8 0.18 12.3 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Pex14_N PF04695.13 EGG13476.1 - 0.0069 17.1 8.9 0.0069 17.1 8.9 6.1 6 0 0 6 6 6 2 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_8 PF13181.6 EGG13476.1 - 0.045 14.0 0.0 0.045 14.0 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG13476.1 - 0.11 12.8 18.3 0.9 9.8 0.1 6.4 5 2 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 PP_kinase_N PF13089.6 EGG13476.1 - 0.15 12.4 5.7 3.9 7.9 0.0 3.2 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain AIF_C PF14721.6 EGG13476.1 - 0.38 11.1 0.1 0.38 11.1 0.1 5.9 5 2 1 6 6 6 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Alpha_L_fucos PF01120.17 EGG13477.1 - 1.5e-123 412.7 11.0 1.8e-123 412.4 11.0 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 EGG13477.1 - 1.4e-15 57.6 0.0 2.6e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Q_salvage PF10343.9 EGG13478.1 - 3.4e-87 292.6 0.1 5.4e-87 291.9 0.1 1.3 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1688 PF07958.11 EGG13478.1 - 0.0001 21.2 0.1 0.14 10.8 0.0 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF1688) Paf67 PF10255.9 EGG13479.1 - 1.3e-128 429.4 9.5 1.7e-128 429.1 9.5 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 PCI PF01399.27 EGG13479.1 - 0.0023 18.4 0.1 0.0061 17.0 0.1 1.8 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 EGG13479.1 - 0.005 16.9 0.3 0.024 14.7 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG13479.1 - 0.12 12.9 0.0 3.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PCI PF01399.27 EGG13480.1 - 5.7e-10 39.6 0.2 4.9e-09 36.6 0.0 2.6 2 1 1 3 3 3 1 PCI domain Mad3_BUB1_I_2 PF17014.5 EGG13480.1 - 0.0093 16.1 0.3 0.026 14.7 0.3 1.8 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein DUF1206 PF06724.11 EGG13481.1 - 3.1e-11 43.2 16.6 0.00012 22.0 0.3 3.3 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) OPA3 PF07047.12 EGG13481.1 - 0.18 11.6 0.7 0.9 9.3 0.0 2.5 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) DUF3844 PF12955.7 EGG13483.1 - 0.0003 20.9 13.2 0.25 11.5 0.0 4.3 4 0 0 4 4 4 3 Domain of unknown function (DUF3844) EGF_2 PF07974.13 EGG13483.1 - 0.00062 20.1 31.8 0.0085 16.4 8.9 2.7 2 0 0 2 2 2 2 EGF-like domain OKR_DC_1 PF01276.20 EGG13484.1 - 0.06 12.1 0.9 1.2 7.8 0.3 2.1 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain AAA PF00004.29 EGG13485.1 - 1.3e-15 58.0 0.0 1.1e-10 42.0 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 EGG13485.1 - 5.4e-13 48.8 0.4 1.8e-12 47.2 0.4 1.9 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 EGG13485.1 - 3.8e-08 33.0 0.0 1.1e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain GRIM-19 PF06212.12 EGG13486.1 - 5.5e-18 65.2 0.0 6.8e-17 61.7 0.0 1.9 1 1 1 2 2 2 2 GRIM-19 protein Amidohydro_2 PF04909.14 EGG13487.1 - 1.4e-25 90.7 0.0 2.6e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Pkinase PF00069.25 EGG13487.1 - 3e-25 89.1 0.0 9.3e-25 87.5 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13487.1 - 7.5e-22 77.9 0.1 1.4e-21 77.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 EGG13487.1 - 1e-17 64.5 3.4 1.8e-12 47.7 0.6 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG13487.1 - 2.3e-15 56.7 0.5 2e-07 31.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) GRAM PF02893.20 EGG13487.1 - 2.9e-14 52.9 0.3 9.5e-14 51.3 0.3 1.9 1 0 0 1 1 1 1 GRAM domain Ank PF00023.30 EGG13487.1 - 1.4e-12 47.4 1.5 0.0052 17.2 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGG13487.1 - 1.8e-11 44.1 0.5 6e-06 26.4 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG13487.1 - 4.2e-11 42.1 0.3 0.0011 19.3 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat bPH_3 PF14470.6 EGG13487.1 - 0.0068 16.7 0.0 0.027 14.8 0.0 2.0 1 0 0 1 1 1 1 Bacterial PH domain REPA_OB_2 PF16900.5 EGG13488.1 - 1.4e-15 57.0 0.5 1.3e-14 53.9 0.3 2.6 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 EGG13488.1 - 9.6e-11 41.5 0.2 4.7e-06 26.5 0.1 2.7 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain TFIIA PF03153.13 EGG13488.1 - 3.1e-05 24.1 20.3 4.3e-05 23.7 20.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit TT_ORF1 PF02956.14 EGG13488.1 - 0.011 14.5 16.6 0.016 13.9 16.6 1.2 1 0 0 1 1 1 0 TT viral orf 1 eIF-3_zeta PF05091.12 EGG13488.1 - 0.016 14.2 16.1 0.023 13.7 16.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDK5_activator PF03261.15 EGG13488.1 - 0.13 11.7 20.6 0.23 10.9 20.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Dapper PF15268.6 EGG13488.1 - 0.28 10.0 13.3 0.35 9.7 13.3 1.1 1 0 0 1 1 1 0 Dapper Spt20 PF12090.8 EGG13488.1 - 0.34 10.5 41.6 0.68 9.5 41.6 1.5 1 0 0 1 1 1 0 Spt20 family DUF4407 PF14362.6 EGG13488.1 - 1.7 7.9 12.8 2.5 7.4 12.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 EGG13488.1 - 1.8 7.3 17.6 2.7 6.7 17.6 1.2 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 EGG13488.1 - 2.5 7.4 10.4 3.9 6.8 10.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Menin PF05053.13 EGG13488.1 - 3 6.1 16.4 4.4 5.6 16.4 1.2 1 0 0 1 1 1 0 Menin SLC12 PF03522.15 EGG13488.1 - 3.1 6.7 16.2 4.8 6.1 16.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF2464 PF10240.9 EGG13488.1 - 4.2 6.9 13.6 4.9 6.6 12.4 1.6 2 0 0 2 2 2 0 Multivesicular body subunit 12 Lin-8 PF03353.15 EGG13488.1 - 4.4 6.8 20.6 7 6.1 20.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Serinc PF03348.15 EGG13488.1 - 5.6 5.8 7.5 8.2 5.2 7.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2756 PF10956.8 EGG13488.1 - 8.7 6.9 50.2 44 4.6 46.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) HCO3_cotransp PF00955.21 EGG13488.1 - 9 5.0 8.9 15 4.3 8.9 1.2 1 0 0 1 1 1 0 HCO3- transporter family REPA_OB_2 PF16900.5 EGG13489.1 - 1.8e-13 50.2 0.1 3.5e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Replication protein A OB domain POT1PC PF16686.5 EGG13489.1 - 2e-05 24.5 0.3 0.00037 20.4 0.0 2.8 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein tRNA_anti-codon PF01336.25 EGG13489.1 - 0.00069 19.6 0.0 0.053 13.5 0.0 3.0 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain POT1 PF02765.17 EGG13489.1 - 0.023 14.5 0.2 0.17 11.7 0.1 2.3 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 CDC24_OB3 PF17244.2 EGG13490.1 - 0.046 13.4 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 DUF5088 PF17008.5 EGG13490.1 - 0.074 12.8 0.2 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5088) GST_C_3 PF14497.6 EGG13491.1 - 1.9e-18 66.5 0.1 3.8e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG13491.1 - 1.2e-08 35.0 0.0 1.8e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGG13491.1 - 4.8e-07 30.0 0.0 1.4e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGG13491.1 - 0.0053 16.7 0.0 0.008 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGG13491.1 - 0.029 14.8 0.0 0.061 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Cullin PF00888.22 EGG13492.1 - 2.9e-156 521.7 22.2 2.9e-156 521.7 22.2 1.6 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EGG13492.1 - 1.2e-26 92.6 4.1 1.2e-26 92.6 4.1 3.1 4 1 0 4 4 4 1 Cullin protein neddylation domain TFIIE_alpha PF02002.17 EGG13492.1 - 0.012 15.4 0.3 0.057 13.3 0.3 2.2 1 0 0 1 1 1 0 TFIIE alpha subunit Rio2_N PF09202.11 EGG13492.1 - 0.042 14.1 3.3 0.17 12.1 0.0 3.3 4 0 0 4 4 4 0 Rio2, N-terminal DnaI_N PF07319.11 EGG13492.1 - 0.2 12.3 0.0 0.2 12.3 0.0 3.6 4 1 0 4 4 4 0 Primosomal protein DnaI N-terminus TrmB PF01978.19 EGG13492.1 - 0.21 11.5 4.0 11 5.9 0.0 4.4 5 0 0 5 5 5 0 Sugar-specific transcriptional regulator TrmB TMEMspv1-c74-12 PF11044.8 EGG13493.1 - 0.0062 16.5 0.2 0.0078 16.2 0.2 1.2 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein Tmemb_9 PF05434.11 EGG13493.1 - 0.033 14.1 0.1 0.035 14.0 0.1 1.0 1 0 0 1 1 1 0 TMEM9 TMEM154 PF15102.6 EGG13493.1 - 0.043 13.7 0.0 0.045 13.7 0.0 1.0 1 0 0 1 1 1 0 TMEM154 protein family OAD_gamma PF04277.13 EGG13493.1 - 0.072 13.7 0.1 0.079 13.6 0.1 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_60s PF00428.19 EGG13493.1 - 3.8 8.1 10.8 4.5 7.9 10.8 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 EGG13493.1 - 9 4.6 5.5 9.5 4.5 5.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Myb_DNA-binding PF00249.31 EGG13494.1 - 3.5e-12 46.3 0.0 7.8e-11 42.0 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 EGG13494.1 - 1.4e-10 41.3 1.0 5.4e-10 39.5 0.1 2.5 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.17 EGG13494.1 - 4.3e-08 32.9 6.9 8.6e-08 31.9 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 EGG13494.1 - 0.00012 22.2 0.0 0.0026 18.0 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain YL1 PF05764.13 EGG13494.1 - 0.00017 21.8 12.1 0.00017 21.8 12.1 2.6 2 1 0 2 2 2 1 YL1 nuclear protein C1_2 PF03107.16 EGG13494.1 - 0.23 11.8 6.2 0.46 10.8 6.2 1.5 1 0 0 1 1 1 0 C1 domain CREPT PF16566.5 EGG13494.1 - 1.7 8.8 8.7 0.16 12.2 1.1 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Rotamase PF00639.21 EGG13496.1 - 2.5e-23 82.9 0.1 5.2e-23 81.8 0.1 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EGG13496.1 - 1.7e-20 73.7 0.2 3.3e-20 72.8 0.2 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain FHA PF00498.26 EGG13496.1 - 6.5e-18 64.9 0.2 1.8e-17 63.4 0.1 1.9 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EGG13496.1 - 9.4e-08 32.3 0.0 2.5e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Rotamase_2 PF13145.6 EGG13496.1 - 0.0074 17.1 0.0 0.014 16.2 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF4274 PF14096.6 EGG13496.1 - 0.048 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) DRY_EERY PF09750.9 EGG13496.1 - 0.23 11.7 1.9 2.1 8.6 0.1 2.7 3 1 0 3 3 3 0 Alternative splicing regulator Lip_prot_lig_C PF10437.9 EGG13497.1 - 1.7e-19 69.6 1.1 4.9e-19 68.1 0.1 2.2 2 1 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.19 EGG13497.1 - 6.2e-08 32.6 0.0 2.3e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Salt_tol_Pase PF09506.10 EGG13497.1 - 0.01 14.7 0.4 0.015 14.1 0.4 1.2 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) DUF4708 PF15813.5 EGG13497.1 - 0.059 12.5 0.1 1 8.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4708) VID27_PH PF17747.1 EGG13497.1 - 0.47 10.8 2.9 7.3 6.9 0.2 2.6 2 1 0 2 2 2 0 VID27 PH-like domain DNA_pol_B PF00136.21 EGG13498.1 - 1e-136 456.3 0.1 1.5e-136 455.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGG13498.1 - 1.2e-82 277.7 0.3 3.2e-82 276.4 0.3 1.8 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGG13498.1 - 1.6e-16 60.6 10.0 1.6e-16 60.6 10.0 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta EB PF01683.18 EGG13498.1 - 0.0011 19.2 17.1 0.018 15.3 3.0 3.0 2 0 0 2 2 2 2 EB module PPP4R2 PF09184.11 EGG13498.1 - 0.01 15.4 4.5 0.028 14.0 4.5 1.6 1 0 0 1 1 1 0 PPP4R2 Ribosomal_60s PF00428.19 EGG13498.1 - 0.046 14.3 4.8 0.1 13.2 4.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Imm5 PF14423.6 EGG13498.1 - 0.14 12.3 1.2 0.37 11.0 1.2 1.7 1 0 0 1 1 1 0 Immunity protein Imm5 TFIIA PF03153.13 EGG13498.1 - 0.42 10.6 13.2 0.89 9.5 13.2 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EGF_2 PF07974.13 EGG13498.1 - 1.1 9.7 33.8 0.083 13.3 11.7 3.0 2 0 0 2 2 2 0 EGF-like domain DUF2846 PF11008.8 EGG13499.1 - 0.018 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) TMEM154 PF15102.6 EGG13500.1 - 0.16 11.8 1.2 0.54 10.1 1.2 1.8 1 0 0 1 1 1 0 TMEM154 protein family EGF_2 PF07974.13 EGG13500.1 - 0.88 10.0 15.7 2.3 8.7 15.7 1.8 1 0 0 1 1 1 0 EGF-like domain zf-CCCH_2 PF14608.6 EGG13501.1 - 2.4e-22 78.6 46.8 6.3e-05 23.3 3.5 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 EGG13501.1 - 1.9e-06 27.6 1.6 1.9e-06 27.6 1.6 5.7 7 2 0 7 7 7 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EGG13501.1 - 0.0003 21.0 22.4 0.019 15.2 5.2 4.1 1 1 2 3 3 3 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 EGG13501.1 - 0.0021 18.1 7.3 0.0021 18.1 7.3 6.2 9 0 0 9 9 8 1 Zinc finger domain ZapB PF06005.12 EGG13501.1 - 0.0076 16.7 3.7 0.015 15.8 3.7 1.4 1 0 0 1 1 1 1 Cell division protein ZapB zf-CCCH_4 PF18044.1 EGG13501.1 - 0.01 15.6 3.4 0.01 15.6 3.4 7.4 6 2 0 6 6 6 0 CCCH-type zinc finger 53-BP1_Tudor PF09038.10 EGG13501.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor CENP-H PF05837.12 EGG13501.1 - 0.24 11.8 1.7 0.51 10.8 1.7 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Colipase-like PF15083.6 EGG13501.1 - 0.67 10.1 17.2 1.7 8.8 0.2 4.1 2 1 3 5 5 5 0 Colipase-like Arena_ncap_C PF17290.2 EGG13501.1 - 1.7 8.0 4.8 0.54 9.6 0.1 2.6 2 1 2 4 4 4 0 Arenavirus nucleocapsid C-terminal domain PIN_11 PF18479.1 EGG13501.1 - 5.1 7.3 6.7 39 4.4 0.4 3.5 1 1 3 4 4 4 0 PIN like domain EGF_2 PF07974.13 EGG13502.1 - 0.0014 18.9 8.1 0.0035 17.7 8.1 1.6 1 0 0 1 1 1 1 EGF-like domain DUF1943 PF09172.11 EGG13502.1 - 0.0042 16.4 0.5 0.0066 15.7 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1943) EGF PF00008.27 EGG13502.1 - 0.023 15.0 6.9 0.051 13.9 6.9 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGG13502.1 - 0.4 11.4 10.5 1.1 10.0 10.5 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF Cyt-b5 PF00173.28 EGG13505.1 - 5.5e-21 74.5 0.1 7e-21 74.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RhoGEF PF00621.20 EGG13506.1 - 2.2e-32 112.8 5.3 2.2e-32 112.8 5.3 1.8 2 0 0 2 2 2 1 RhoGEF domain IQ PF00612.27 EGG13506.1 - 2.1e-05 23.9 2.2 3.9e-05 23.1 2.2 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif Vpu PF00558.19 EGG13506.1 - 0.079 12.7 0.1 0.26 11.1 0.1 1.9 1 0 0 1 1 1 0 Vpu protein Choline_transpo PF04515.12 EGG13506.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Plasma-membrane choline transporter WD40 PF00400.32 EGG13507.1 - 2.4e-15 56.6 1.4 2.4e-05 25.0 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 EGG13507.1 - 6.5e-07 28.4 3.5 0.00016 20.5 1.5 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGG13507.1 - 9.7e-05 21.5 1.4 0.15 11.0 0.1 3.1 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EGG13507.1 - 0.00013 22.2 0.2 0.034 14.4 0.1 3.3 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGG13507.1 - 0.0032 16.3 3.2 0.067 11.9 1.3 2.3 1 1 0 2 2 2 1 Nup133 N terminal like WD40_3 PF15911.5 EGG13507.1 - 0.057 13.4 0.7 5.5 7.1 0.0 2.9 1 1 1 2 2 2 0 WD domain, G-beta repeat MtrB PF05440.12 EGG13507.1 - 0.13 12.7 0.2 0.33 11.4 0.2 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B Big_7 PF17957.1 EGG13507.1 - 0.49 11.2 5.3 0.43 11.4 0.9 2.6 2 1 0 2 2 2 0 Bacterial Ig domain DUF3642 PF12182.8 EGG13507.1 - 2.4 8.5 7.0 1.7 9.0 3.9 2.2 2 0 0 2 2 2 0 Bacterial lipoprotein Mito_carr PF00153.27 EGG13508.1 - 3.9e-69 228.7 1.1 9.7e-25 86.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DHR-2 PF06920.13 EGG13509.1 - 2.5e-46 158.4 8.0 8.7e-46 156.6 7.6 1.9 1 1 0 1 1 1 1 Dock homology region 2 F-box-like PF12937.7 EGG13509.1 - 1.5e-07 31.1 0.1 4.2e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG13509.1 - 0.11 12.4 0.0 0.52 10.3 0.0 2.2 1 0 0 1 1 1 0 F-box domain EPL1 PF10513.9 EGG13510.1 - 0.00038 20.9 0.5 0.99 9.8 0.1 2.1 2 0 0 2 2 2 2 Enhancer of polycomb-like DUF5310 PF17237.2 EGG13510.1 - 0.027 14.4 0.2 0.067 13.1 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5310) NFRKB_winged PF14465.6 EGG13510.1 - 0.073 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 NFRKB Winged Helix-like PIG-P PF08510.12 EGG13510.1 - 0.58 10.1 19.3 0.03 14.2 5.6 3.2 2 0 0 2 2 2 0 PIG-P RRM_1 PF00076.22 EGG13511.1 - 4.9e-17 61.5 0.1 8.2e-17 60.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG13511.1 - 0.047 13.3 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tubulin PF00091.25 EGG13513.1 - 2e-69 233.7 0.1 4.6e-69 232.6 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGG13513.1 - 1.5e-42 144.8 0.1 2.5e-42 144.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGG13513.1 - 8.6e-07 29.3 0.9 1.1e-06 28.9 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGG13513.1 - 0.0001 22.0 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGG13513.1 - 0.022 14.0 0.0 0.076 12.2 0.0 1.8 2 0 0 2 2 2 0 Tubulin like SEC-C PF02810.15 EGG13514.1 - 9.1e-06 25.5 13.7 1.8e-05 24.5 13.7 1.6 1 0 0 1 1 1 1 SEC-C motif CAP_C PF08603.11 EGG13514.1 - 0.00026 20.7 1.6 0.00043 19.9 1.6 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DUF4139 PF13598.6 EGG13514.1 - 0.023 14.4 0.1 0.036 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Peptidase_S28 PF05577.12 EGG13515.1 - 2.9e-77 260.3 3.8 3.7e-77 259.9 3.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 EGG13515.1 - 1.4e-06 27.2 0.0 2.9e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 EGG13515.1 - 0.0013 18.5 0.1 0.0086 15.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG13515.1 - 0.057 12.7 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LRR19-TM PF15176.6 EGG13516.1 - 0.058 13.4 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Glycophorin_A PF01102.18 EGG13516.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.7 3 0 0 3 3 3 0 Glycophorin A Syndecan PF01034.20 EGG13516.1 - 0.44 10.5 1.9 0.94 9.4 1.9 1.5 1 0 0 1 1 1 0 Syndecan domain Metallophos PF00149.28 EGG13517.1 - 3e-17 63.8 0.1 3e-17 63.8 0.1 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG13517.1 - 0.0021 18.3 0.0 0.004 17.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain O-antigen_lig PF13425.6 EGG13517.1 - 0.14 11.0 2.6 0.22 10.3 2.6 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF2286 PF10051.9 EGG13518.1 - 0.1 12.3 0.2 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) TCR PF03638.15 EGG13519.1 - 1.6e-24 85.9 50.9 1.6e-13 50.7 19.7 2.3 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 EGG13519.1 - 0.0074 16.4 40.5 0.018 15.1 16.4 2.8 2 0 0 2 2 2 2 CXC domain of E3 ubiquitin-protein ligase MSL2 ABC2_membrane PF01061.24 EGG13520.1 - 3.9e-84 281.3 53.6 1.5e-43 148.7 28.8 2.8 4 0 0 4 4 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGG13520.1 - 1.8e-49 167.8 1.3 5.5e-26 91.7 0.1 3.1 3 0 0 3 3 3 2 ABC transporter RsgA_GTPase PF03193.16 EGG13520.1 - 2.8e-08 33.8 0.3 0.0027 17.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGG13520.1 - 5.4e-07 29.3 0.7 0.0028 17.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG13520.1 - 3.5e-06 27.5 0.0 0.056 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EGG13520.1 - 9e-06 25.7 0.2 0.24 11.2 0.0 3.6 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGG13520.1 - 3.7e-05 23.8 0.1 0.24 11.5 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EGG13520.1 - 3.9e-05 23.9 0.2 0.39 11.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGG13520.1 - 5.4e-05 23.5 0.2 1.1 9.7 0.0 3.4 3 0 0 3 3 3 2 RNA helicase Rad17 PF03215.15 EGG13520.1 - 6.9e-05 22.8 0.1 0.35 10.8 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_25 PF13481.6 EGG13520.1 - 0.00013 21.6 0.6 0.25 10.9 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 EGG13520.1 - 0.00062 20.3 8.2 0.25 11.9 0.0 4.2 5 0 0 5 5 3 2 AAA domain AAA_33 PF13671.6 EGG13520.1 - 0.00072 19.7 0.1 0.04 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EGG13520.1 - 0.0011 19.4 0.1 0.35 11.3 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PDR_assoc PF08370.11 EGG13520.1 - 0.0012 18.5 0.6 0.0012 18.5 0.6 3.6 3 0 0 3 3 2 1 Plant PDR ABC transporter associated IstB_IS21 PF01695.17 EGG13520.1 - 0.0014 18.4 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 EGG13520.1 - 0.0067 16.7 0.2 5.6 7.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGG13520.1 - 0.026 14.4 2.0 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 EGG13520.1 - 0.03 14.2 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EGG13520.1 - 0.065 12.5 0.0 8.6 5.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 EGG13520.1 - 0.085 13.4 11.7 1.1 9.7 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.6 EGG13520.1 - 0.093 12.4 0.4 7.8 6.2 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGG13520.1 - 0.41 10.6 2.6 16 5.5 0.1 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PDR_CDR PF06422.12 EGG13520.1 - 1 9.3 11.5 0.48 10.3 0.5 3.1 3 0 0 3 3 2 0 CDR ABC transporter WD40 PF00400.32 EGG13522.1 - 1.5e-05 25.7 9.3 0.066 14.1 0.3 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat C1_1 PF00130.22 EGG13522.1 - 5.7e-05 22.9 7.4 5.7e-05 22.9 7.4 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF859 PF05895.12 EGG13522.1 - 0.085 11.3 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) zf-RING_9 PF13901.6 EGG13522.1 - 0.095 12.7 4.2 0.22 11.5 4.2 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD PF00628.29 EGG13522.1 - 0.12 12.3 5.6 0.28 11.1 5.6 1.7 1 0 0 1 1 1 0 PHD-finger RAP1 PF07218.11 EGG13522.1 - 4.9 5.3 5.6 7.1 4.8 5.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BAR_3 PF16746.5 EGG13523.1 - 1.5e-05 24.8 12.4 2.2e-05 24.3 12.4 1.3 1 0 0 1 1 1 1 BAR domain of APPL family Rsbr_N PF08678.10 EGG13523.1 - 0.013 15.6 1.5 0.025 14.6 0.4 2.0 2 1 0 2 2 2 0 Rsbr N terminal DLP_helical PF18709.1 EGG13523.1 - 0.02 14.1 5.9 0.039 13.2 5.9 1.4 1 0 0 1 1 1 0 Dynamin-like helical domain DUF3452 PF11934.8 EGG13523.1 - 0.59 9.7 4.3 0.31 10.6 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) CARDB PF07705.11 EGG13526.1 - 0.049 13.9 1.1 0.15 12.3 1.1 1.8 1 1 0 1 1 1 0 CARDB TRAP_beta PF05753.14 EGG13526.1 - 0.55 9.6 2.7 0.86 9.0 1.3 2.0 1 1 1 2 2 2 0 Translocon-associated protein beta (TRAPB) Fascin PF06268.13 EGG13527.1 - 0.0011 19.2 0.1 2.4 8.4 0.0 2.4 2 0 0 2 2 2 2 Fascin domain Acetyltransf_2 PF00797.17 EGG13528.1 - 1.1e-34 120.3 1.0 4.8e-19 69.1 0.1 2.2 2 0 0 2 2 2 2 N-acetyltransferase GidB PF02527.15 EGG13528.1 - 0.011 15.1 0.1 0.5 9.7 0.0 2.2 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G RtcR PF06956.11 EGG13528.1 - 0.045 13.2 0.1 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Regulator of RNA terminal phosphate cyclase DUF4508 PF14969.6 EGG13528.1 - 0.15 12.4 0.0 21 5.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) LisH PF08513.11 EGG13528.1 - 0.95 9.5 4.3 4.2 7.5 0.2 2.5 2 0 0 2 2 2 0 LisH MCRS_N PF13325.6 EGG13529.1 - 1.3e-14 54.6 4.2 1.3e-14 54.6 4.2 4.8 4 2 0 5 5 5 1 N-terminal region of micro-spherule protein MIF4G PF02854.19 EGG13529.1 - 5.8e-07 29.4 6.7 5.8e-07 29.4 6.7 3.1 3 0 0 3 3 3 1 MIF4G domain FHA PF00498.26 EGG13529.1 - 3.5e-06 27.3 0.1 1.1e-05 25.6 0.1 2.0 1 0 0 1 1 1 1 FHA domain Fumble PF03630.14 EGG13529.1 - 1.7 7.8 8.0 0.048 12.8 1.1 1.9 2 0 0 2 2 2 0 Fumble Ycf34 PF10718.9 EGG13529.1 - 9.2 7.0 8.0 2.6 8.8 0.2 4.0 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Rad50_zn_hook PF04423.14 EGG13530.1 - 0.063 13.1 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif BT1 PF03092.16 EGG13530.1 - 0.19 9.9 0.0 0.19 9.9 0.0 1.0 1 0 0 1 1 1 0 BT1 family Dickkopf_N PF04706.12 EGG13532.1 - 0.00021 21.7 6.3 0.00021 21.7 6.3 6.5 3 2 3 6 6 6 1 Dickkopf N-terminal cysteine-rich region TIG PF01833.24 EGG13533.1 - 1.9e-24 85.6 116.7 3e-05 24.0 1.5 14.9 11 2 2 13 13 13 11 IPT/TIG domain Lectin_C PF00059.21 EGG13533.1 - 0.0015 19.2 0.0 0.0056 17.4 0.0 2.0 1 0 0 1 1 1 1 Lectin C-type domain EGF_2 PF07974.13 EGG13533.1 - 0.02 15.2 14.1 0.042 14.2 14.1 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EGG13533.1 - 0.62 10.2 7.2 2 8.6 7.2 1.9 1 0 0 1 1 1 0 Tenascin EGF domain Laminin_EGF PF00053.24 EGG13533.1 - 2.1 8.5 8.3 4.4 7.5 8.3 1.5 1 0 0 1 1 1 0 Laminin EGF domain Methyltransf_4 PF02390.17 EGG13534.1 - 1.3e-23 83.4 0.0 1.3e-23 83.4 0.0 2.7 2 0 0 2 2 2 1 Putative methyltransferase PPR_2 PF13041.6 EGG13534.1 - 7.9e-10 38.8 0.1 6.9e-08 32.6 0.0 3.2 3 0 0 3 3 3 1 PPR repeat family PPR_3 PF13812.6 EGG13534.1 - 4.2e-08 33.2 0.4 0.0003 20.8 0.0 4.0 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EGG13534.1 - 0.00035 20.0 0.0 0.00084 18.8 0.0 1.6 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EGG13534.1 - 0.0087 15.7 0.5 4.4 7.1 0.1 2.8 2 0 0 2 2 2 2 PPR repeat LSM PF01423.22 EGG13535.1 - 9.8e-19 66.8 0.2 1.2e-18 66.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGG13535.1 - 0.043 13.9 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 EGG13535.1 - 0.088 12.9 0.1 0.15 12.2 0.1 1.4 1 1 0 1 1 1 0 Scd6-like Sm domain FNIP PF05725.12 EGG13536.1 - 1.3e-15 57.3 29.2 5.2e-10 39.3 0.0 8.5 5 1 2 7 7 7 4 FNIP Repeat F-box-like PF12937.7 EGG13536.1 - 0.085 12.8 0.1 0.4 10.6 0.0 2.2 2 1 0 2 2 2 0 F-box-like DUF1462 PF07315.11 EGG13536.1 - 0.11 12.8 0.1 0.7 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) Acyltransferase PF01553.21 EGG13537.1 - 4.4e-05 23.1 0.0 0.00017 21.3 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase ECH_2 PF16113.5 EGG13538.1 - 2.5e-78 263.9 0.0 3.7e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGG13538.1 - 2.1e-13 50.2 0.0 1.3e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ARL2_Bind_BART PF11527.8 EGG13538.1 - 0.56 10.3 3.8 0.72 10.0 1.0 2.4 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART RIFIN PF02009.16 EGG13539.1 - 0.00046 20.2 3.3 0.00053 20.0 3.3 1.2 1 0 0 1 1 1 1 Rifin DUF3112 PF11309.8 EGG13539.1 - 0.0025 17.3 1.9 0.0025 17.3 1.9 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3112) Spem1 PF15670.5 EGG13539.1 - 0.0069 16.0 0.6 0.0081 15.8 0.6 1.3 1 0 0 1 1 1 1 Spermatid maturation protein 1 Zn-C2H2_12 PF18112.1 EGG13539.1 - 0.017 15.6 0.2 0.04 14.4 0.2 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain PI3K_1B_p101 PF10486.9 EGG13539.1 - 0.025 12.4 5.6 0.028 12.2 5.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit UPF0524 PF15823.5 EGG13539.1 - 0.033 13.6 3.8 0.041 13.3 3.8 1.1 1 0 0 1 1 1 0 UPF0524 of C3orf70 PIEZO PF15917.5 EGG13539.1 - 0.045 13.2 5.3 0.06 12.8 5.3 1.1 1 0 0 1 1 1 0 Piezo PBP1_TM PF14812.6 EGG13539.1 - 0.052 13.9 2.5 0.35 11.3 0.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Orf78 PF06024.12 EGG13539.1 - 0.065 13.5 1.1 0.065 13.5 1.1 2.2 2 0 0 2 2 2 0 Orf78 (ac78) Mito_fiss_reg PF05308.11 EGG13539.1 - 0.068 13.3 7.8 0.1 12.7 7.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator SR-25 PF10500.9 EGG13539.1 - 0.068 12.8 12.6 0.099 12.2 12.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EVI2A PF05399.11 EGG13539.1 - 0.073 12.7 11.1 0.12 12.0 11.1 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) SLC12 PF03522.15 EGG13539.1 - 0.09 11.8 6.6 0.12 11.4 6.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 EGG13539.1 - 0.16 11.1 2.5 0.23 10.6 2.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ALMT PF11744.8 EGG13539.1 - 0.32 9.8 2.6 0.4 9.5 2.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Suf PF05843.14 EGG13539.1 - 0.72 9.8 10.0 0.99 9.3 10.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 EGG13539.1 - 1.1 7.9 5.7 1.3 7.6 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup E7 PF00527.18 EGG13539.1 - 1.2 9.4 8.3 3 8.1 0.8 3.0 2 1 0 3 3 3 0 E7 protein, Early protein Med13_C PF06333.12 EGG13539.1 - 1.5 8.0 12.2 2.1 7.5 12.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain GCD14 PF08704.10 EGG13539.1 - 3.9 7.1 9.9 0.1 12.3 1.3 1.9 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Macoilin PF09726.9 EGG13539.1 - 7.4 5.0 12.0 9.3 4.7 12.0 1.1 1 0 0 1 1 1 0 Macoilin family FNIP PF05725.12 EGG13540.1 - 2.9e-62 206.6 76.4 2.2e-06 27.7 0.0 26.9 24 4 5 30 30 30 14 FNIP Repeat Zn-C2H2_12 PF18112.1 EGG13540.1 - 4.9e-07 30.1 6.7 0.71 10.4 0.2 4.0 3 0 0 3 3 3 3 Autophagy receptor zinc finger-C2H2 domain DUF4922 PF16269.5 EGG13540.1 - 1.3e-05 25.1 7.9 0.59 9.9 0.2 4.3 4 0 0 4 4 4 3 Domain of unknown function (DUF4922) zf-C2H2_4 PF13894.6 EGG13540.1 - 0.0001 22.8 11.7 2.4 9.2 0.5 4.4 3 0 0 3 3 3 3 C2H2-type zinc finger Corona_NS8 PF12093.8 EGG13540.1 - 0.0028 18.2 0.1 48 4.6 0.0 5.3 5 0 0 5 5 5 0 Coronavirus NS8 protein ADD_DNMT3 PF17980.1 EGG13540.1 - 0.035 14.1 3.4 49 4.0 0.1 4.0 3 0 0 3 3 3 0 Cysteine rich ADD domain in DNMT3 DUF4451 PF14616.6 EGG13540.1 - 0.44 10.7 4.7 53 4.0 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4451) Rad50_zn_hook PF04423.14 EGG13540.1 - 1.3 8.9 3.2 1.5e+02 2.3 0.1 3.5 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Paramyx-P PF13008.7 EGG13540.1 - 5.9 6.4 12.3 4.3 6.9 0.4 3.2 3 0 0 3 3 3 0 Zinc-binding domain of Paramyxoviridae V protein DUF974 PF06159.13 EGG13541.1 - 1e-46 159.7 0.1 3.3e-46 158.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF974) Transglut_C PF00927.22 EGG13541.1 - 0.011 15.8 0.1 6.7 6.9 0.0 3.3 3 1 0 3 3 3 0 Transglutaminase family, C-terminal ig like domain Secretin_N_2 PF07655.13 EGG13542.1 - 0.27 11.8 13.7 1.5 9.4 11.3 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain FNIP PF05725.12 EGG13543.1 - 2.4e-19 69.2 20.5 9e-07 29.0 0.8 7.1 6 1 1 7 7 7 4 FNIP Repeat Cpn60_TCP1 PF00118.24 EGG13544.1 - 5.2e-149 497.0 13.2 5.9e-149 496.8 13.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_1b PF00579.25 EGG13545.1 - 9.6e-65 218.8 0.2 1.6e-64 218.1 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Trans_reg_C PF00486.28 EGG13545.1 - 0.14 12.2 0.0 0.55 10.4 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Ribosomal_L27e PF01777.18 EGG13545.1 - 0.18 12.2 1.8 0.8 10.1 0.1 2.7 2 1 0 2 2 2 0 Ribosomal L27e protein family DNA_pol3_beta_3 PF02768.15 EGG13546.1 - 0.048 13.5 0.3 11 5.9 0.1 2.5 1 1 1 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain 4HBT PF03061.22 EGG13547.1 - 7.5e-05 23.0 0.1 0.074 13.4 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily SPX PF03105.19 EGG13547.1 - 0.086 12.7 27.2 0.04 13.9 4.7 2.5 2 1 0 2 2 2 0 SPX domain ketoacyl-synt PF00109.26 EGG13549.1 - 3.3e-66 223.5 0.1 5.5e-66 222.7 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG13549.1 - 2e-48 165.6 0.0 3.3e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGG13549.1 - 2.3e-36 124.4 0.1 1e-35 122.3 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGG13549.1 - 1.9e-26 93.1 0.1 1e-25 90.7 0.1 2.3 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGG13549.1 - 8.9e-21 74.4 0.0 1.7e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGG13549.1 - 2.7e-15 56.8 0.7 1.6e-14 54.3 0.1 2.5 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGG13549.1 - 2.1e-10 41.8 0.0 2.4e-08 35.1 0.0 3.0 3 0 0 3 3 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EGG13549.1 - 4.4e-06 27.0 0.0 3.7e-05 24.0 0.1 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 EGG13549.1 - 1.1e-05 25.4 0.0 2.8e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG13549.1 - 3.4e-05 23.7 0.1 0.00011 22.0 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGG13549.1 - 0.00021 20.7 0.1 0.00058 19.3 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain F-box-like PF12937.7 EGG13550.1 - 4.3e-05 23.3 1.1 0.013 15.4 2.2 2.6 2 0 0 2 2 2 2 F-box-like SelK_SelG PF10961.8 EGG13550.1 - 0.027 15.1 0.0 0.066 13.8 0.0 1.6 1 0 0 1 1 1 0 Selenoprotein SelK_SelG ketoacyl-synt PF00109.26 EGG13551.1 - 4.4e-60 203.4 0.0 8.1e-60 202.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG13551.1 - 5.8e-51 173.9 0.0 9.6e-51 173.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGG13551.1 - 2.3e-30 105.0 0.2 4.6e-29 100.8 0.1 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGG13551.1 - 1.1e-29 103.6 2.4 1.5e-28 99.9 0.2 3.0 3 0 0 3 3 3 1 KR domain KAsynt_C_assoc PF16197.5 EGG13551.1 - 2.3e-17 63.4 0.2 1e-16 61.4 0.2 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGG13551.1 - 7.8e-14 51.6 0.0 3e-10 39.8 0.0 3.3 1 1 1 2 2 2 2 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EGG13551.1 - 6.4e-10 40.2 0.0 7.7e-07 30.2 0.0 3.0 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGG13551.1 - 3.3e-07 30.3 0.0 2.5e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EGG13551.1 - 4e-06 27.1 0.0 1.2e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EGG13551.1 - 7.9e-06 25.7 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGG13551.1 - 2.1e-05 24.0 0.1 0.00019 20.9 0.1 2.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_12 PF08242.12 EGG13551.1 - 0.047 14.4 4.4 0.85 10.4 0.1 3.8 3 0 0 3 3 3 0 Methyltransferase domain DUF3781 PF12636.7 EGG13551.1 - 0.066 13.1 3.4 0.083 12.8 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3781) Svs_4_5_6 PF17381.2 EGG13551.1 - 0.89 10.6 5.7 4.8 8.2 5.7 2.3 1 0 0 1 1 1 0 Seminal vesicle secretory proteins 4/5/6 FNIP PF05725.12 EGG13553.1 - 3e-21 75.3 13.0 2.2e-05 24.5 0.3 7.2 6 1 1 8 8 8 5 FNIP Repeat DUF1971 PF09313.11 EGG13553.1 - 0.036 14.1 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) FNIP PF05725.12 EGG13554.1 - 3.5e-13 49.5 5.5 4.9e-05 23.4 0.0 7.3 7 1 2 9 9 9 5 FNIP Repeat FNIP PF05725.12 EGG13555.1 - 1.8e-16 60.0 18.8 0.00083 19.5 0.0 8.9 8 1 1 9 9 9 6 FNIP Repeat Dicty_CAD PF05720.12 EGG13555.1 - 1e-08 35.0 0.1 2.9e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 Cell-cell adhesion domain SHE3 PF17078.5 EGG13555.1 - 0.059 13.1 4.3 0.11 12.2 4.3 1.4 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 SR-25 PF10500.9 EGG13555.1 - 0.11 12.1 2.3 0.22 11.1 2.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Adeno_E3B PF03376.14 EGG13555.1 - 0.14 12.4 0.1 2.8 8.2 0.0 2.8 2 0 0 2 2 2 0 Adenovirus E3B protein Acyl_transf_1 PF00698.21 EGG13556.1 - 1.5e-49 169.2 0.0 2.8e-49 168.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EGG13556.1 - 3.6e-29 101.9 1.2 9.8e-29 100.5 0.2 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGG13556.1 - 8e-23 81.1 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EGG13556.1 - 3.9e-10 40.9 0.0 4.8e-07 30.9 0.0 2.8 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGG13556.1 - 8.8e-06 25.7 0.0 9.3e-05 22.4 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG13556.1 - 1.1e-05 25.3 0.0 2.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGG13556.1 - 7.2e-05 23.1 0.0 0.00027 21.2 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 EGG13556.1 - 0.076 13.8 0.2 6.8 7.5 0.0 3.1 2 0 0 2 2 2 0 Methyltransferase domain ketoacyl-synt PF00109.26 EGG13557.1 - 9.1e-60 202.3 0.0 1.3e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGG13557.1 - 1.6e-37 128.1 0.1 3e-36 124.0 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGG13557.1 - 1.8e-12 47.7 0.5 3.5e-12 46.8 0.5 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EGG13557.1 - 2.4e-06 27.1 0.0 6.2e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain FNIP PF05725.12 EGG13558.1 - 4.6e-23 81.1 13.8 0.0014 18.7 0.0 9.9 7 2 4 11 11 11 9 FNIP Repeat Lambda_tail_I PF06805.12 EGG13558.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I Ribosomal_L15e PF00827.17 EGG13559.1 - 5.5e-88 293.7 5.6 5.5e-88 293.7 5.6 2.5 2 0 0 2 2 2 1 Ribosomal L15 BRCT_2 PF16589.5 EGG13559.1 - 0.00016 22.0 0.7 0.026 14.9 0.0 4.4 4 0 0 4 4 4 1 BRCT domain, a BRCA1 C-terminus domain MMR_HSR1 PF01926.23 EGG13559.1 - 0.0009 19.3 10.3 0.0031 17.6 0.1 4.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase BRCT PF00533.26 EGG13559.1 - 0.0036 17.7 4.1 0.014 15.7 0.0 3.8 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain AAA_16 PF13191.6 EGG13559.1 - 0.031 14.7 0.7 0.31 11.4 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EGG13559.1 - 0.052 14.0 0.0 0.052 14.0 0.0 8.3 6 3 0 6 6 6 0 ABC transporter AAA_29 PF13555.6 EGG13559.1 - 0.083 12.6 0.0 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGG13559.1 - 0.12 12.6 0.0 0.12 12.6 0.0 4.4 4 0 0 4 4 4 0 AAA domain MitMem_reg PF13012.6 EGG13560.1 - 1.2e-24 86.9 2.9 3.5e-24 85.4 2.9 1.9 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGG13560.1 - 1e-22 80.3 0.3 2.1e-22 79.3 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TFIIA PF03153.13 EGG13560.1 - 0.035 14.1 6.7 0.046 13.7 6.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3729 PF12526.8 EGG13560.1 - 0.13 13.8 1.8 0.23 13.0 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) MyTH4 PF00784.17 EGG13561.1 - 2.1e-43 147.2 0.6 2.1e-20 73.2 0.1 2.7 2 0 0 2 2 2 2 MyTH4 domain SH3_1 PF00018.28 EGG13561.1 - 0.047 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.6 EGG13561.1 - 0.08 12.8 0.2 1.9 8.4 0.0 2.6 3 0 0 3 3 3 0 Variant SH3 domain Myosin_head PF00063.21 EGG13562.1 - 4.1e-141 471.5 27.0 4.8e-138 461.3 27.0 2.3 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 EGG13562.1 - 0.03 14.6 0.3 0.81 10.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain SKICH PF17751.1 EGG13563.1 - 1.4e-15 57.7 1.3 7.5e-05 23.2 0.1 4.4 3 0 0 3 3 3 3 SKICH domain HECW_N PF16562.5 EGG13563.1 - 7.3e-12 45.2 0.5 0.0087 15.8 0.0 3.7 2 1 1 3 3 3 3 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 CUE PF02845.16 EGG13563.1 - 2.3e-06 27.2 0.6 0.0063 16.2 0.1 2.7 2 0 0 2 2 2 2 CUE domain Herpes_UL52 PF03121.15 EGG13563.1 - 1.2e-05 25.1 0.9 1.2e-05 25.1 0.9 1.9 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase fn3_3 PF14686.6 EGG13563.1 - 0.0026 17.5 1.5 1.9 8.3 0.0 2.8 2 0 0 2 2 2 2 Polysaccharide lyase family 4, domain II FNIP PF05725.12 EGG13564.1 - 1e-34 118.4 21.4 1.8e-06 28.0 0.0 10.5 9 2 0 10 10 10 6 FNIP Repeat FNIP PF05725.12 EGG13565.1 - 6.2e-42 141.5 37.8 2.6e-05 24.3 0.2 14.6 11 3 5 16 16 16 11 FNIP Repeat Adeno_E3B PF03376.14 EGG13565.1 - 0.0092 16.2 0.7 17 5.7 0.0 3.6 4 0 0 4 4 4 2 Adenovirus E3B protein Zn-C2H2_12 PF18112.1 EGG13565.1 - 0.53 10.8 1.9 0.72 10.4 0.1 2.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain FNIP PF05725.12 EGG13566.1 - 4.7e-24 84.3 27.5 2.4e-09 37.2 0.0 8.8 7 2 3 10 10 10 7 FNIP Repeat Zn-C2H2_12 PF18112.1 EGG13566.1 - 0.06 13.8 0.2 0.17 12.4 0.2 1.7 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Adeno_E3B PF03376.14 EGG13566.1 - 0.098 12.9 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Adenovirus E3B protein zf-C2H2_4 PF13894.6 EGG13566.1 - 0.13 13.2 0.5 0.53 11.3 0.5 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger FNIP PF05725.12 EGG13567.1 - 1.5e-26 92.3 16.5 1.4e-05 25.1 0.0 9.7 7 2 3 10 10 10 8 FNIP Repeat EF-hand_1 PF00036.32 EGG13568.1 - 0.07 12.7 0.1 0.1 12.2 0.1 1.4 1 1 0 1 1 1 0 EF hand Dockerin_1 PF00404.18 EGG13568.1 - 0.088 13.0 0.0 0.088 13.0 0.0 1.1 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_7 PF13499.6 EGG13569.1 - 3.2e-08 33.9 2.7 8.8e-05 22.9 0.3 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGG13569.1 - 8.6e-07 28.1 0.3 0.00073 18.9 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGG13569.1 - 4.4e-06 26.2 0.4 0.0085 15.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EGG13569.1 - 0.04 13.8 0.1 0.073 12.9 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGG13569.1 - 0.052 13.9 0.7 1 9.7 0.2 2.0 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4201 PF13870.6 EGG13569.1 - 0.099 12.4 0.7 0.13 12.0 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) HECT PF00632.25 EGG13570.1 - 1.9e-62 211.5 0.0 3e-62 210.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MSC PF09402.10 EGG13570.1 - 0.048 13.1 0.6 0.11 11.9 0.6 1.5 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain AATF-Che1 PF13339.6 EGG13570.1 - 0.18 12.5 3.2 0.26 12.0 0.6 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Secretin_N_2 PF07655.13 EGG13570.1 - 0.71 10.4 19.7 2.4 8.7 5.4 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain FNIP PF05725.12 EGG13571.1 - 2.7e-13 49.8 15.4 0.0032 17.6 0.0 9.2 8 3 0 8 8 8 5 FNIP Repeat Utp21 PF04192.12 EGG13573.1 - 4.2e-53 180.2 4.1 1.4e-52 178.5 4.1 1.8 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EGG13573.1 - 1.6e-18 66.7 9.2 0.012 16.4 0.0 9.7 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG13573.1 - 1.6e-15 57.2 0.0 3.2e-05 24.1 0.0 6.4 2 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGG13573.1 - 7e-06 25.8 0.1 0.026 14.1 0.1 3.7 1 1 2 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.16 EGG13573.1 - 2.8e-05 22.8 0.3 0.11 11.0 0.1 2.8 2 1 0 2 2 2 2 Cytochrome D1 heme domain HPS3_N PF14761.6 EGG13573.1 - 0.0013 18.4 0.0 2 7.9 0.0 3.5 3 0 0 3 3 3 2 Hermansky-Pudlak syndrome 3 Utp12 PF04003.12 EGG13573.1 - 0.0013 19.0 0.4 0.0031 17.8 0.4 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 EGG13573.1 - 0.0049 15.6 1.1 0.79 8.3 0.1 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EGG13573.1 - 0.0061 16.6 0.0 2.9 8.0 0.0 3.8 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 EGG13573.1 - 0.034 13.1 1.8 7.5 5.4 0.0 4.0 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EGG13573.1 - 0.06 11.7 0.1 0.19 10.0 0.0 1.8 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz SWIRM PF04433.17 EGG13574.1 - 8.2e-29 99.8 0.1 3.2e-28 97.9 0.1 2.0 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EGG13574.1 - 1.5e-22 79.3 4.7 1.5e-22 79.3 4.7 1.8 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EGG13574.1 - 1.4e-12 47.5 0.0 3e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG13574.1 - 4.7e-06 26.8 0.3 1.5e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM-assoc_3 PF16498.5 EGG13574.1 - 0.16 12.2 1.5 0.42 10.9 1.5 1.7 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal DHHC PF01529.20 EGG13575.1 - 1.8e-05 24.9 1.7 1.8e-05 24.9 1.7 2.6 1 1 1 2 2 2 1 DHHC palmitoyltransferase KH_6 PF15985.5 EGG13576.1 - 7.9e-13 48.5 0.1 1.4e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 EGG13576.1 - 1.1e-05 25.2 0.0 3.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain ECR1_N PF14382.6 EGG13576.1 - 0.024 14.4 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region PRELI PF04707.14 EGG13577.1 - 0.0003 20.6 0.4 0.00042 20.2 0.4 1.2 1 0 0 1 1 1 1 PRELI-like family NapB PF03892.14 EGG13577.1 - 0.00067 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Nitrate reductase cytochrome c-type subunit (NapB) DUF2505 PF10698.9 EGG13577.1 - 0.0014 18.8 0.0 0.0019 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) RCC1 PF00415.18 EGG13578.1 - 6.2e-41 138.8 6.0 1.3e-09 38.5 0.0 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG13578.1 - 4e-17 61.5 14.1 3.2e-06 26.8 0.1 6.3 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Dak1 PF02733.17 EGG13578.1 - 0.084 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Dak1 domain YadA_anchor PF03895.15 EGG13578.1 - 0.9 9.7 4.5 16 5.7 3.7 2.6 2 0 0 2 2 2 0 YadA-like membrane anchor domain Ribonuclease_3 PF00636.26 EGG13579.1 - 0.0063 17.1 0.0 0.028 15.1 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain BCDHK_Adom3 PF10436.9 EGG13580.1 - 0.0023 17.8 0.2 0.9 9.4 0.1 2.7 2 0 0 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF4548 PF15081.6 EGG13583.1 - 0.95 9.3 5.5 0.19 11.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4548) DUF1027 PF06265.11 EGG13584.1 - 0.045 13.7 0.4 0.46 10.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) LRR_8 PF13855.6 EGG13586.1 - 5.4e-05 22.9 8.9 0.00024 20.8 1.0 4.8 4 0 0 4 4 4 1 Leucine rich repeat RCC1 PF00415.18 EGG13587.1 - 1.1e-72 240.5 30.0 8.9e-15 55.1 0.2 9.3 10 0 0 10 10 10 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG13587.1 - 5.6e-37 124.8 40.4 9.4e-08 31.7 0.8 8.7 9 0 0 9 9 9 8 Regulator of chromosome condensation (RCC1) repeat tRNA-synt_1b PF00579.25 EGG13588.1 - 7.6e-64 215.8 0.1 1e-63 215.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF5635 PF18685.1 EGG13588.1 - 0.14 12.1 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5635) DUF5518 PF17647.1 EGG13589.1 - 0.067 13.3 0.3 0.086 13.0 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5518) E1-E2_ATPase PF00122.20 EGG13589.1 - 0.073 12.6 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 E1-E2 ATPase zf-NF-X1 PF01422.17 EGG13590.1 - 8.7e-08 32.1 33.9 8.3e-06 25.7 14.8 16.2 15 1 0 15 15 15 9 NF-X1 type zinc finger Lipl32 PF12103.8 EGG13590.1 - 0.14 11.8 1.2 0.28 10.8 1.2 1.4 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order Hid1 PF12722.7 EGG13591.1 - 0.39 8.8 11.4 0.55 8.3 11.4 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 EGG13591.1 - 0.59 9.3 7.9 1 8.5 7.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3807 PF12720.7 EGG13591.1 - 1.8 8.8 13.7 3.7 7.8 13.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SLC12 PF03522.15 EGG13591.1 - 3.6 6.5 11.0 6.4 5.7 11.0 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Glyco_transf_49 PF13896.6 EGG13592.1 - 9.8e-52 176.3 4.0 1.9e-41 142.5 0.5 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 EGG13592.1 - 0.038 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 PHD PF00628.29 EGG13593.1 - 3.2e-12 46.1 27.3 1.5e-06 28.0 4.9 3.5 3 0 0 3 3 3 3 PHD-finger zf-HC5HC2H PF13771.6 EGG13593.1 - 4.3e-08 33.3 27.4 0.00076 19.7 2.3 3.6 1 1 2 3 3 3 3 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EGG13593.1 - 3.6e-07 30.3 26.5 0.0058 16.8 2.8 3.5 1 1 2 3 3 3 3 PHD-zinc-finger like domain C1_1 PF00130.22 EGG13593.1 - 3.6 7.6 33.7 0.05 13.5 3.9 3.9 2 1 2 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 EGG13593.1 - 3.8 7.9 29.9 0.58 10.5 1.9 3.7 3 0 0 3 3 3 0 Ring finger domain zf-RING-like PF08746.11 EGG13593.1 - 4.9 7.5 21.3 3.2 8.1 3.3 3.8 3 0 0 3 3 3 0 RING-like domain Pkinase PF00069.25 EGG13594.1 - 1.6e-61 208.0 0.0 3.2e-61 207.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13594.1 - 2.9e-42 144.8 0.0 4.6e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG13594.1 - 0.00095 18.6 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGG13594.1 - 0.0025 16.6 4.3 0.0031 16.4 0.0 2.8 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 EGG13594.1 - 0.0074 16.2 0.0 0.021 14.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF2796 PF10986.8 EGG13594.1 - 0.11 12.5 6.1 0.37 10.7 6.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) zf-RING_2 PF13639.6 EGG13595.1 - 2.2e-10 40.7 3.0 5.8e-10 39.3 3.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG13595.1 - 1.6e-07 31.0 2.0 4.5e-07 29.6 2.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGG13595.1 - 1.2e-06 28.2 0.5 3.5e-06 26.7 0.5 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EGG13595.1 - 7.7e-06 26.1 3.7 7.7e-06 26.1 3.7 3.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGG13595.1 - 5.1e-05 23.1 1.6 0.00011 22.1 1.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGG13595.1 - 6.2e-05 22.8 1.6 0.00012 21.8 1.6 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG13595.1 - 0.00016 21.5 2.9 0.00033 20.5 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RNA_pol_3_Rpc31 PF11705.8 EGG13595.1 - 0.0066 16.7 12.6 0.0066 16.7 12.6 3.7 2 1 1 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 zf-ANAPC11 PF12861.7 EGG13595.1 - 0.021 14.8 1.0 0.021 14.8 1.0 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger CR6_interact PF10147.9 EGG13597.1 - 0.0049 16.6 0.0 0.017 14.9 0.1 1.7 2 0 0 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Helicase_C PF00271.31 EGG13599.1 - 1.7e-19 70.2 0.1 5.9e-19 68.4 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 EGG13599.1 - 6.9e-14 52.3 6.4 1.3e-13 51.4 0.6 3.7 4 0 0 4 4 4 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EGG13599.1 - 8.7e-09 35.5 2.1 2e-08 34.4 0.4 2.4 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 DEAD PF00270.29 EGG13599.1 - 1.3e-05 25.0 0.4 0.00055 19.7 0.1 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 EGG13599.1 - 0.0085 16.1 0.3 0.038 14.0 0.0 2.4 3 0 0 3 3 3 1 Flavivirus DEAD domain ResIII PF04851.15 EGG13599.1 - 0.046 13.7 3.6 0.049 13.6 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGG13599.1 - 0.047 12.9 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Dicer_dimer PF03368.14 EGG13599.1 - 0.048 13.8 0.5 0.22 11.7 0.5 2.2 1 0 0 1 1 1 0 Dicer dimerisation domain SUIM_assoc PF16619.5 EGG13600.1 - 0.49 10.5 6.3 0.096 12.8 1.4 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HMA PF00403.26 EGG13603.1 - 2.9e-09 37.2 1.3 3.8e-09 36.9 1.3 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Tetraspanin PF00335.20 EGG13604.1 - 5.1e-05 23.1 0.6 5.6e-05 23.0 0.6 1.1 1 0 0 1 1 1 1 Tetraspanin family Tmemb_170 PF10190.9 EGG13604.1 - 0.00029 21.2 0.6 0.00045 20.6 0.6 1.4 1 0 0 1 1 1 1 Putative transmembrane protein 170 Glucos_trans_II PF14264.6 EGG13604.1 - 0.0027 17.1 1.5 0.0032 16.9 1.5 1.0 1 0 0 1 1 1 1 Glucosyl transferase GtrII COX1 PF00115.20 EGG13604.1 - 0.0085 15.0 0.2 0.0098 14.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I CcmD PF04995.14 EGG13604.1 - 0.041 14.0 0.7 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) RRM_1 PF00076.22 EGG13605.1 - 6.3e-28 96.4 0.0 3e-14 52.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 EGG13605.1 - 1.3e-16 60.3 0.3 1.3e-16 60.3 0.3 2.0 2 0 0 2 2 2 1 Surp module CTD_bind PF04818.13 EGG13605.1 - 3.3e-12 47.1 0.0 8.3e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_occluded PF16842.5 EGG13605.1 - 6.8e-06 25.9 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif CTK3 PF12243.8 EGG13605.1 - 0.0027 17.7 0.8 0.0063 16.5 0.1 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 Adaptin_binding PF10199.9 EGG13605.1 - 0.043 14.4 4.0 0.11 13.1 4.0 1.7 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 GRP PF07172.11 EGG13605.1 - 9.8 6.9 27.0 3.4 8.4 8.2 2.6 2 0 0 2 2 2 0 Glycine rich protein family YceD PF02620.17 EGG13607.1 - 0.1 12.8 0.0 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD PH PF00169.29 EGG13608.1 - 2.1e-16 60.3 0.1 4.1e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGG13608.1 - 2.9e-06 27.6 4.0 3.5e-05 24.2 1.1 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain HMA PF00403.26 EGG13608.1 - 9.3e-05 22.8 0.1 0.00019 21.8 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain PH_3 PF14593.6 EGG13608.1 - 0.0015 18.6 0.1 0.003 17.6 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGG13608.1 - 0.0041 17.4 0.2 0.0075 16.5 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Adaptin_N PF01602.20 EGG13609.1 - 5.7e-150 500.3 13.0 8.2e-150 499.8 13.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGG13609.1 - 1.4e-65 220.3 5.2 7.9e-63 211.3 0.5 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 EGG13609.1 - 2.5e-25 88.7 0.1 8.1e-25 87.1 0.1 2.0 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 EGG13609.1 - 1.6e-17 63.6 1.3 4.3e-05 23.8 0.0 5.5 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 EGG13609.1 - 1.4e-09 37.4 3.5 0.13 12.6 0.0 5.9 5 0 0 5 5 5 3 HEAT repeat Cnd3 PF12719.7 EGG13609.1 - 4.6e-05 22.8 1.3 0.00085 18.6 0.1 3.0 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain Alpha_adaptinC2 PF02883.20 EGG13609.1 - 0.0004 20.7 0.3 0.0004 20.7 0.3 2.3 2 1 0 2 2 2 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 EGG13609.1 - 0.00059 20.0 4.1 2.1 8.6 0.0 5.2 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EGG13609.1 - 0.002 17.7 3.3 1.1 8.8 0.1 4.0 3 2 0 3 3 3 2 CLASP N terminal Arm PF00514.23 EGG13609.1 - 0.046 13.8 4.0 32 4.8 0.0 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Presenilin PF01080.17 EGG13609.1 - 0.086 11.6 1.2 0.17 10.6 1.2 1.5 1 0 0 1 1 1 0 Presenilin Mistic PF11458.8 EGG13609.1 - 0.47 10.4 5.0 1.8 8.6 0.3 3.2 3 0 0 3 3 3 0 Membrane-integrating protein Mistic Spt5_N PF11942.8 EGG13609.1 - 7.3 7.6 9.2 18 6.4 9.2 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PCI PF01399.27 EGG13610.1 - 4.7e-14 52.8 1.7 6.6e-14 52.3 0.1 2.2 2 2 0 2 2 2 1 PCI domain IL5 PF02025.15 EGG13610.1 - 0.0055 17.0 0.5 0.03 14.6 0.1 2.4 2 0 0 2 2 2 1 Interleukin 5 TPR_1 PF00515.28 EGG13610.1 - 0.03 14.1 1.4 0.03 14.1 1.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DASH_Dam1 PF08653.10 EGG13610.1 - 0.11 12.3 5.6 1.1 9.1 0.2 3.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 TPR_2 PF07719.17 EGG13610.1 - 0.43 10.8 4.6 0.16 12.2 1.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat V-SNARE_C PF12352.8 EGG13610.1 - 0.58 10.5 3.4 15 5.9 0.1 3.4 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus HBM PF16591.5 EGG13610.1 - 0.62 9.4 2.9 1.8 7.9 0.1 2.8 3 0 0 3 3 3 0 Helical bimodular sensor domain TGT PF01702.18 EGG13611.1 - 5.9e-143 476.2 0.0 7.3e-143 475.9 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DEAD PF00270.29 EGG13612.1 - 7.4e-46 156.1 0.4 1.1e-45 155.5 0.4 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG13612.1 - 5.8e-29 100.7 2.0 4.9e-28 97.7 0.6 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG13612.1 - 1e-06 28.9 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGG13612.1 - 0.00086 18.6 0.1 0.0013 18.0 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA PF00004.29 EGG13612.1 - 0.13 12.7 0.5 0.68 10.4 0.1 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGG13612.1 - 0.17 12.1 0.3 0.52 10.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain Yop-YscD_cpl PF16697.5 EGG13613.1 - 0.019 15.2 0.0 0.08 13.3 0.0 2.0 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain CPSF100_C PF13299.6 EGG13613.1 - 0.072 13.3 19.1 1.9 8.7 1.2 3.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal FHA PF00498.26 EGG13613.1 - 0.094 13.1 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 FHA domain YL1 PF05764.13 EGG13613.1 - 0.25 11.5 29.2 0.39 10.8 5.4 2.3 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 EGG13613.1 - 0.44 8.8 20.9 0.7 8.1 9.4 2.2 2 0 0 2 2 2 0 CDC45-like protein DNApol_Exo PF18136.1 EGG13613.1 - 0.65 9.1 10.1 0.17 11.0 2.0 2.3 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain PPL5 PF18168.1 EGG13613.1 - 4.3 6.6 16.1 3.5 6.8 1.0 2.4 2 0 0 2 2 2 0 Prim-pol family 5 Phage_integrase PF00589.22 EGG13614.1 - 0.046 13.5 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family PPR_2 PF13041.6 EGG13614.1 - 0.071 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 PPR repeat family PPR PF01535.20 EGG13614.1 - 0.15 12.4 0.3 0.3 11.4 0.1 1.7 2 0 0 2 2 2 0 PPR repeat UPF1_Zn_bind PF09416.10 EGG13615.1 - 8.8e-67 223.8 1.3 1.8e-66 222.8 1.3 1.6 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EGG13615.1 - 1.4e-61 207.6 0.0 2.3e-61 206.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGG13615.1 - 3.9e-44 151.4 0.4 9e-27 94.5 0.1 3.2 3 1 1 4 4 4 2 AAA domain DUF5599 PF18141.1 EGG13615.1 - 7.3e-25 87.0 0.1 1.6e-24 85.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EGG13615.1 - 9e-12 45.1 0.0 5.1e-11 42.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG13615.1 - 5.9e-10 39.6 0.0 1.9e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EGG13615.1 - 0.00068 19.4 2.7 0.28 10.9 0.0 3.2 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EGG13615.1 - 0.0014 17.9 0.2 0.085 12.1 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EGG13615.1 - 0.0025 17.8 0.0 0.0089 16.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EGG13615.1 - 0.0034 16.9 1.7 0.079 12.5 0.0 3.1 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 EGG13615.1 - 0.023 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 EGG13615.1 - 0.026 14.8 0.0 0.1 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGG13615.1 - 0.054 13.5 0.0 0.39 10.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EGG13615.1 - 0.065 13.7 0.0 0.43 11.0 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 EGG13615.1 - 0.068 13.0 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 Helicase PhoH PF02562.16 EGG13615.1 - 0.21 11.0 0.0 0.54 9.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein RNA_polI_A34 PF08208.11 EGG13616.1 - 2e-26 93.4 37.5 2e-26 93.4 37.5 2.3 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Borrelia_P83 PF05262.11 EGG13616.1 - 0.82 8.1 41.6 0.95 7.9 41.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ALMT PF11744.8 EGG13616.1 - 5.6 5.7 28.7 7.4 5.3 28.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter CDC27 PF09507.10 EGG13616.1 - 6 6.1 67.9 8.3 5.7 67.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 F-box-like PF12937.7 EGG13617.1 - 1.4e-07 31.3 0.2 1.4e-07 31.3 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGG13617.1 - 1.9e-07 30.8 0.0 1.9e-07 30.8 0.0 2.0 2 1 0 2 2 2 1 F-box domain BTK PF00779.19 EGG13617.1 - 0.0097 15.7 0.6 0.026 14.4 0.6 1.7 1 0 0 1 1 1 1 BTK motif Peripla_BP_4 PF13407.6 EGG13617.1 - 0.6 9.6 7.8 2.8 7.4 0.7 3.1 3 0 0 3 3 3 0 Periplasmic binding protein domain CBM9_2 PF16011.5 EGG13618.1 - 1.6e-05 24.7 0.0 2.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate-binding family 9 bZIP_Maf PF03131.17 EGG13619.1 - 3e-06 27.6 10.1 3e-06 27.6 10.1 3.3 3 0 0 3 3 3 1 bZIP Maf transcription factor bZIP_1 PF00170.21 EGG13619.1 - 0.00041 20.4 12.3 0.00041 20.4 12.3 2.0 2 0 0 2 2 2 1 bZIP transcription factor LPMO_10 PF03067.15 EGG13620.1 - 2.8e-05 24.8 0.1 3.4e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Ependymin PF00811.18 EGG13621.1 - 0.045 14.0 1.3 0.11 12.8 0.1 2.1 1 1 0 2 2 2 0 Ependymin ILEI PF15711.5 EGG13622.1 - 7e-64 212.3 0.2 1.4e-14 54.3 0.0 5.8 5 0 0 5 5 5 5 Interleukin-like EMT inducer DUF2722 PF10846.8 EGG13622.1 - 0.0001 21.4 5.9 0.00015 20.9 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Glyco_hydro_92 PF07971.12 EGG13622.1 - 0.013 14.4 1.1 0.024 13.6 1.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 Pex14_N PF04695.13 EGG13622.1 - 0.21 12.2 6.8 0.19 12.4 5.0 1.8 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 EGG13622.1 - 0.45 10.1 21.5 0.81 9.2 21.5 1.3 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.10 EGG13622.1 - 0.68 8.5 17.2 1 8.0 17.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 EGG13622.1 - 0.71 9.8 15.0 1.2 9.1 15.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fer2_3 PF13085.6 EGG13622.1 - 0.73 9.9 0.0 0.73 9.9 0.0 2.4 3 0 0 3 3 2 0 2Fe-2S iron-sulfur cluster binding domain Med3 PF11593.8 EGG13622.1 - 1.1 8.4 15.7 1.4 8.0 14.2 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal RHS_repeat PF05593.14 EGG13622.1 - 1.4 9.6 3.6 6.5 7.4 0.0 3.3 3 0 0 3 3 3 0 RHS Repeat DUF4834 PF16118.5 EGG13622.1 - 5.2 8.1 8.4 12 7.0 8.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) UPF0560 PF10577.9 EGG13622.1 - 5.3 5.4 8.9 7.7 4.9 8.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 BSP_II PF05432.11 EGG13623.1 - 0.0022 17.8 18.6 0.0022 17.8 18.6 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) RXT2_N PF08595.11 EGG13623.1 - 0.0031 17.5 9.8 0.0037 17.3 9.8 1.1 1 0 0 1 1 1 1 RXT2-like, N-terminal FYDLN_acid PF09538.10 EGG13623.1 - 0.014 16.1 9.0 0.015 16.0 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SDA1 PF05285.12 EGG13623.1 - 0.015 14.8 17.8 0.015 14.7 17.8 1.1 1 0 0 1 1 1 0 SDA1 DUF2052 PF09747.9 EGG13623.1 - 0.022 14.9 14.1 0.025 14.7 14.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DNA_pol_phi PF04931.13 EGG13623.1 - 0.032 12.4 21.6 0.031 12.4 21.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi RPN2_C PF18004.1 EGG13623.1 - 0.037 14.0 7.1 0.041 13.8 7.1 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CobT PF06213.12 EGG13623.1 - 0.038 13.4 13.5 0.037 13.4 13.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tim54 PF11711.8 EGG13623.1 - 0.053 12.3 5.2 0.058 12.2 5.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Prothymosin PF03247.14 EGG13623.1 - 0.064 13.7 29.2 0.093 13.2 29.2 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family TRAP_alpha PF03896.16 EGG13623.1 - 0.072 12.3 8.8 0.071 12.3 8.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CPSF100_C PF13299.6 EGG13623.1 - 0.072 13.3 3.5 0.08 13.1 3.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nop53 PF07767.11 EGG13623.1 - 0.082 12.3 14.8 0.088 12.2 14.8 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PTPRCAP PF15713.5 EGG13623.1 - 0.09 13.1 15.1 0.099 12.9 15.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DAP PF15228.6 EGG13623.1 - 0.11 13.7 0.3 0.15 13.2 0.3 1.3 1 0 0 1 1 1 0 Death-associated protein Nop14 PF04147.12 EGG13623.1 - 0.16 10.2 19.1 0.16 10.1 19.1 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 EGG13623.1 - 0.28 11.6 3.8 0.32 11.4 3.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2457 PF10446.9 EGG13623.1 - 0.3 10.2 20.7 0.33 10.0 20.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Presenilin PF01080.17 EGG13623.1 - 0.3 9.8 2.5 0.26 10.0 2.5 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGG13623.1 - 0.37 9.0 13.3 0.36 9.1 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 EGG13623.1 - 0.56 9.9 2.7 0.64 9.7 2.7 1.1 1 0 0 1 1 1 0 Connexin DUF4484 PF14831.6 EGG13623.1 - 0.91 9.5 9.0 1.2 9.2 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) PI3K_1B_p101 PF10486.9 EGG13623.1 - 1.1 6.9 7.2 1 7.0 7.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Paf1 PF03985.13 EGG13623.1 - 1.1 8.1 19.3 1.3 7.9 19.3 1.1 1 0 0 1 1 1 0 Paf1 Zip PF02535.22 EGG13623.1 - 1.2 8.3 2.9 1.1 8.4 2.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 EGG13623.1 - 1.3 7.9 4.0 1.3 7.9 4.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 EGG13623.1 - 1.3 8.3 17.1 1.3 8.3 17.1 1.0 1 0 0 1 1 1 0 BUD22 DUF4637 PF15470.6 EGG13623.1 - 1.4 8.6 17.6 1.9 8.2 17.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RAB3GAP2_C PF14656.6 EGG13623.1 - 1.4 7.0 4.2 1.4 7.0 4.2 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF3464 PF11947.8 EGG13623.1 - 1.7 8.4 3.4 2.5 7.8 3.4 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Sporozoite_P67 PF05642.11 EGG13623.1 - 1.8 6.5 10.1 2.1 6.3 10.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HsdM_N PF12161.8 EGG13623.1 - 1.9 9.1 5.9 2.4 8.8 5.9 1.2 1 0 0 1 1 1 0 HsdM N-terminal domain DUF2254 PF10011.9 EGG13623.1 - 2.8 6.7 7.4 4.3 6.1 0.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) V_ATPase_I PF01496.19 EGG13623.1 - 3.5 5.4 4.6 4.2 5.2 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NOA36 PF06524.12 EGG13623.1 - 4 6.7 20.4 5.1 6.3 20.4 1.1 1 0 0 1 1 1 0 NOA36 protein Pes-10 PF07149.11 EGG13623.1 - 6.4 5.7 17.5 6.1 5.8 17.5 1.2 1 0 0 1 1 1 0 Pes-10 COBRA1 PF06209.13 EGG13626.1 - 1.3e-73 248.5 6.8 2.1e-73 247.8 6.8 1.3 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) SOG2 PF10428.9 EGG13626.1 - 1 8.5 30.1 0.4 9.8 25.7 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein SR-25 PF10500.9 EGG13626.1 - 5.5 6.5 19.3 12 5.4 19.3 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Lin-8 PF03353.15 EGG13626.1 - 9.8 5.6 6.7 22 4.5 6.7 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cyclin PF08613.11 EGG13627.1 - 0.00014 22.3 1.2 0.00014 22.3 1.2 2.8 2 2 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGG13627.1 - 0.00071 19.3 0.1 0.00071 19.3 0.1 2.7 3 0 0 3 3 3 1 Cyclin, N-terminal domain DUF2407_C PF13373.6 EGG13627.1 - 1.2 9.4 5.2 2.2 8.5 5.2 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain Proteasome PF00227.26 EGG13628.1 - 2.5e-33 115.2 0.0 3.1e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.25 EGG13629.1 - 2.4e-43 148.4 3.5 1.1e-40 139.6 0.1 3.4 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13629.1 - 2.1e-36 125.5 1.4 7.4e-35 120.5 0.3 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase RasGEF_N PF00618.20 EGG13629.1 - 1.1e-10 41.6 0.6 1.1e-10 41.6 0.6 3.7 4 1 0 4 4 4 1 RasGEF N-terminal motif RasGEF PF00617.19 EGG13629.1 - 1e-09 38.9 3.7 6.6e-09 36.2 3.7 2.5 1 1 0 1 1 1 1 RasGEF domain APH PF01636.23 EGG13629.1 - 4.4e-05 23.5 0.0 6.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG13629.1 - 0.00048 19.5 0.3 0.0013 18.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGG13629.1 - 0.0022 17.4 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SSP160 PF06933.11 EGG13629.1 - 0.0044 15.3 39.5 0.0093 14.2 4.7 3.2 3 0 0 3 3 3 2 Special lobe-specific silk protein SSP160 Inos-1-P_synth PF01658.17 EGG13629.1 - 0.02 15.2 0.6 0.3 11.4 0.1 2.5 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase RlaP PF10127.9 EGG13629.1 - 0.037 13.6 0.1 0.068 12.7 0.1 1.3 1 0 0 1 1 1 0 RNA repair pathway DNA polymerase beta family Abhydro_lipase PF04083.16 EGG13630.1 - 4.5e-17 61.4 0.0 1e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGG13630.1 - 9.4e-06 25.4 1.9 2e-05 24.4 0.8 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG13630.1 - 1.3e-05 24.6 0.0 0.0025 17.1 0.0 2.6 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG13630.1 - 0.0031 18.2 0.0 0.0045 17.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UAA PF08449.11 EGG13631.1 - 7.4e-65 219.1 16.5 8.7e-65 218.9 16.5 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGG13631.1 - 3.4e-10 40.2 27.7 1.1e-07 32.1 9.8 3.1 2 1 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 EGG13631.1 - 0.007 15.3 7.7 0.006 15.6 6.7 1.5 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like IMUP PF15761.5 EGG13631.1 - 6.6 7.5 13.0 13 6.5 13.0 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein ILEI PF15711.5 EGG13633.1 - 7.7e-15 55.1 0.0 1.5e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Interleukin-like EMT inducer RP-C_C PF11800.8 EGG13634.1 - 0.1 12.7 5.4 0.028 14.5 2.0 1.7 2 0 0 2 2 2 0 Replication protein C C-terminal region ABC_tran_Xtn PF12848.7 EGG13636.1 - 0.041 13.9 1.0 0.11 12.6 1.0 1.7 1 0 0 1 1 1 0 ABC transporter DDE_Tnp_4 PF13359.6 EGG13637.1 - 1e-22 80.5 0.1 1.5e-22 79.9 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 EGG13637.1 - 0.00016 21.4 0.5 0.00038 20.1 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease ARD PF03079.14 EGG13639.1 - 3.1e-45 154.2 0.3 3.7e-45 153.9 0.3 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EGG13639.1 - 1.8e-10 40.3 0.0 2.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGG13639.1 - 6.5e-06 26.1 0.0 9.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EGG13639.1 - 0.0019 17.8 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Cupin ETC_C1_NDUFA4 PF04800.12 EGG13641.1 - 8.6e-28 96.4 0.0 1.6e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ribosomal_S27e PF01667.17 EGG13642.1 - 3.1e-11 42.8 1.0 4.2e-11 42.4 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 SRP54 PF00448.22 EGG13643.1 - 6.2e-52 176.1 1.1 3.5e-51 173.6 1.1 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 EGG13643.1 - 4.2e-51 174.6 20.5 5.6e-51 174.2 20.5 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 EGG13643.1 - 2.9e-07 30.6 0.1 1.8e-06 28.1 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 EGG13643.1 - 3.6e-05 23.6 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EGG13643.1 - 6.7e-05 22.0 0.0 0.00017 20.6 0.0 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EGG13643.1 - 0.00011 22.3 2.7 0.00081 19.5 0.3 3.0 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 EGG13643.1 - 0.00016 21.3 1.5 0.0005 19.7 0.5 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EGG13643.1 - 0.00035 20.5 0.0 0.25 11.2 0.0 2.9 2 0 0 2 2 2 2 NTPase AAA_22 PF13401.6 EGG13643.1 - 0.00069 19.9 0.2 0.0046 17.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGG13643.1 - 0.0097 16.3 0.0 0.041 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 EGG13643.1 - 0.01 15.2 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_31 PF13614.6 EGG13643.1 - 0.011 15.6 0.3 0.24 11.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 EGG13643.1 - 0.012 15.1 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.20 EGG13643.1 - 0.054 13.4 0.0 0.18 11.7 0.0 1.9 1 1 0 1 1 1 0 Adenylylsulphate kinase VirC1 PF07015.11 EGG13643.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 VirC1 protein SPOUT_MTase PF02590.17 EGG13643.1 - 1.4 8.8 0.0 1.4 8.8 0.0 2.7 3 0 0 3 3 3 0 Predicted SPOUT methyltransferase CDC27 PF09507.10 EGG13643.1 - 3.3 7.0 30.7 4.6 6.5 30.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Exo84_C PF16528.5 EGG13646.1 - 8.6e-34 117.1 1.0 8.6e-34 117.1 1.0 2.0 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EGG13646.1 - 8.6e-05 22.6 1.3 0.0003 20.8 0.2 2.5 2 1 0 2 2 2 1 Vps51/Vps67 DAGK_prokar PF01219.19 EGG13646.1 - 0.13 12.2 0.1 0.46 10.3 0.1 1.9 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase COG5 PF10392.9 EGG13646.1 - 1.3 9.2 6.2 1.5 9.0 0.3 3.6 4 1 0 4 4 4 0 Golgi transport complex subunit 5 DENN PF02141.21 EGG13647.1 - 8.1e-54 182.4 7.2 2.4e-53 180.9 7.2 1.9 1 0 0 1 1 1 1 DENN (AEX-3) domain WD40 PF00400.32 EGG13647.1 - 3.5e-39 132.1 37.5 1.2e-05 26.0 0.1 8.8 8 0 0 8 8 8 8 WD domain, G-beta repeat uDENN PF03456.18 EGG13647.1 - 2.6e-15 56.9 1.0 1.2e-14 54.8 1.0 2.3 1 0 0 1 1 1 1 uDENN domain C2 PF00168.30 EGG13647.1 - 2.5e-11 43.8 1.0 7.6e-11 42.2 1.0 1.8 1 0 0 1 1 1 1 C2 domain WD40_like PF17005.5 EGG13647.1 - 6.3e-08 32.3 5.5 0.0007 19.0 0.2 2.5 1 1 1 2 2 2 2 WD40-like domain dDENN PF03455.19 EGG13647.1 - 6.7e-08 32.4 0.6 6.7e-08 32.4 0.6 3.0 2 0 0 2 2 2 1 dDENN domain SBF2 PF12335.8 EGG13647.1 - 1.5e-06 28.0 0.7 1.5e-06 28.0 0.7 3.2 3 0 0 3 3 3 1 Myotubularin protein Nup160 PF11715.8 EGG13647.1 - 2.1e-05 23.4 10.2 0.2 10.3 0.4 4.6 2 2 3 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGG13647.1 - 0.0013 19.0 4.2 2.2 8.6 0.1 4.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DDE_Tnp_4 PF13359.6 EGG13649.1 - 4.6e-14 52.4 0.0 7.2e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease ILEI PF15711.5 EGG13649.1 - 2.7e-12 47.0 0.0 6.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Interleukin-like EMT inducer NUC194 PF08163.12 EGG13650.1 - 2e-57 194.9 2.9 2e-57 194.9 2.9 2.5 2 0 0 2 2 2 1 NUC194 domain PI3_PI4_kinase PF00454.27 EGG13650.1 - 5.7e-51 173.7 0.3 6.6e-50 170.2 0.0 2.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EGG13650.1 - 2.8e-16 59.7 11.5 6.5e-16 58.5 7.8 2.7 2 1 0 2 2 2 1 FAT domain FATC PF02260.20 EGG13650.1 - 3.2e-11 42.8 0.3 1.1e-10 41.1 0.3 2.0 1 0 0 1 1 1 1 FATC domain DUF1539 PF07560.11 EGG13650.1 - 1.6 8.9 13.8 0.4 10.8 1.1 5.0 5 0 0 5 5 5 0 Domain of Unknown Function (DUF1539) Ribosomal_60s PF00428.19 EGG13652.1 - 0.0056 17.2 1.8 0.017 15.7 0.6 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein Nop52 PF05997.12 EGG13652.1 - 0.017 14.9 0.2 0.088 12.6 0.2 2.2 1 0 0 1 1 1 0 Nucleolar protein,Nop52 DUF913 PF06025.12 EGG13652.1 - 0.047 12.7 6.6 0.4 9.6 1.0 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) FAM60A PF15396.6 EGG13652.1 - 2.5 8.1 11.2 2.5 8.1 0.8 3.1 3 0 0 3 3 3 0 Protein Family FAM60A PBP1_TM PF14812.6 EGG13652.1 - 3.3 8.2 6.1 0.43 11.0 1.6 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 EGG13652.1 - 3.6 7.6 9.2 0.064 13.3 1.4 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Afi1 PF07792.12 EGG13652.1 - 6 7.3 11.6 0.39 11.2 2.9 2.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NOA36 PF06524.12 EGG13652.1 - 6.1 6.1 15.7 0.054 12.8 6.9 1.8 2 0 0 2 2 2 0 NOA36 protein Inositol_P PF00459.25 EGG13653.1 - 5.6e-38 131.0 0.0 6.5e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family XAP5 PF04921.14 EGG13654.1 - 1.5e-74 251.0 26.4 1.5e-74 251.0 26.4 3.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator BET PF17035.5 EGG13655.1 - 3.9e-17 62.2 0.3 3.9e-17 62.2 0.3 3.1 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 EGG13655.1 - 6.4e-17 61.4 0.0 1.5e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_28 PF13521.6 EGG13656.1 - 1.1e-20 74.5 0.0 1.3e-20 74.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain Pribosyltran PF00156.27 EGG13657.1 - 2.8e-16 59.4 0.0 4e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGG13657.1 - 2.1e-05 24.1 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EGG13657.1 - 0.046 13.2 0.1 0.055 13.0 0.1 1.3 1 1 0 1 1 1 0 Phosphoribosyl transferase PPR_2 PF13041.6 EGG13658.1 - 0.064 13.5 0.2 4.5 7.6 0.0 3.7 3 0 0 3 3 3 0 PPR repeat family DUF3128 PF11326.8 EGG13658.1 - 2.4 8.6 5.5 0.27 11.6 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) Histone PF00125.24 EGG13659.1 - 3.4e-52 176.3 1.7 3.8e-52 176.1 1.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGG13659.1 - 2.5e-05 24.3 0.1 4.5e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGG13659.1 - 0.0001 22.6 0.0 0.00017 21.9 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EGG13659.1 - 0.00023 21.8 0.4 0.00027 21.5 0.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EGG13659.1 - 0.068 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGG13659.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RICTOR_phospho PF14665.6 EGG13660.1 - 0.01 16.2 1.1 0.062 13.6 0.1 2.2 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site SET PF00856.28 EGG13662.1 - 1.2e-21 77.8 0.3 1.2e-21 77.8 0.3 5.3 4 3 0 4 4 4 1 SET domain AWS PF17907.1 EGG13662.1 - 7.3e-11 41.9 4.1 7.3e-11 41.9 4.1 2.1 2 0 0 2 2 2 1 AWS domain AT_hook PF02178.19 EGG13662.1 - 0.0068 16.2 21.5 0.15 12.0 2.5 4.4 3 0 0 3 3 3 3 AT hook motif DHO_dh PF01180.21 EGG13663.1 - 3.8e-34 118.2 0.0 1.2e-33 116.6 0.0 1.8 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 EGG13663.1 - 2e-31 108.1 2.9 2e-31 108.1 2.9 2.5 2 1 1 3 3 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 EGG13663.1 - 1.3e-22 79.6 11.5 1.3e-22 79.6 11.5 3.9 4 1 0 4 4 4 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 EGG13663.1 - 2.7e-13 49.8 0.0 3.8e-11 42.7 0.0 1.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG13663.1 - 1.2e-05 25.4 0.0 3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Dus PF01207.17 EGG13663.1 - 1.4e-05 24.4 0.1 7.9e-05 21.9 0.1 2.2 3 0 0 3 3 3 1 Dihydrouridine synthase (Dus) Fer4_7 PF12838.7 EGG13663.1 - 3.7e-05 24.2 7.7 3.7e-05 24.2 7.7 3.7 3 0 0 3 3 2 2 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 EGG13663.1 - 6.2e-05 22.4 0.0 0.056 12.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_6 PF12837.7 EGG13663.1 - 0.00021 21.2 1.8 0.00021 21.2 1.8 5.0 6 0 0 6 6 4 3 4Fe-4S binding domain Pyr_redox PF00070.27 EGG13663.1 - 0.00026 21.5 0.0 1.7 9.3 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_10 PF13237.6 EGG13663.1 - 0.00034 20.7 28.0 0.0011 19.0 9.1 3.9 3 2 0 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EGG13663.1 - 0.0011 18.9 38.4 0.0061 16.6 2.2 5.3 6 0 0 6 6 5 3 4Fe-4S binding domain Fer4 PF00037.27 EGG13663.1 - 0.0014 18.4 14.4 0.005 16.6 2.5 4.8 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_9 PF13187.6 EGG13663.1 - 0.0027 17.9 9.9 0.0027 17.9 9.9 3.3 3 0 0 3 3 2 2 4Fe-4S dicluster domain DAO PF01266.24 EGG13663.1 - 0.03 13.9 0.0 0.071 12.7 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EGG13663.1 - 0.097 12.7 0.0 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Fer4_15 PF13459.6 EGG13663.1 - 0.15 12.8 7.0 3.5 8.4 0.6 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_17 PF13534.6 EGG13663.1 - 1.4 9.5 23.5 0.8 10.3 0.8 4.3 4 1 1 5 5 4 0 4Fe-4S dicluster domain RecA PF00154.21 EGG13664.1 - 6.5e-130 432.3 0.6 8.2e-130 432.0 0.6 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 EGG13664.1 - 1.5e-13 50.6 0.1 6.1e-13 48.6 0.1 1.8 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 EGG13664.1 - 3.3e-10 39.7 0.6 8.2e-08 31.9 0.6 3.0 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 EGG13664.1 - 0.00043 20.3 3.3 0.0013 18.7 0.0 2.6 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGG13664.1 - 0.00062 19.5 0.3 0.0014 18.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGG13664.1 - 0.0027 18.0 0.0 0.0069 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGG13664.1 - 0.0028 18.1 0.0 0.0085 16.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CobU PF02283.16 EGG13664.1 - 0.0033 17.0 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_25 PF13481.6 EGG13664.1 - 0.0067 16.0 0.2 0.03 13.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGG13664.1 - 0.011 16.3 2.1 0.053 14.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_35 PF14516.6 EGG13664.1 - 0.041 12.7 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.6 EGG13664.1 - 0.059 13.9 1.1 0.16 12.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 EGG13664.1 - 0.085 12.9 0.7 0.37 10.8 0.0 2.5 2 2 1 3 3 3 0 AAA domain TP53IP5 PF15331.6 EGG13664.1 - 0.37 10.9 4.5 0.66 10.1 4.5 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Presenilin PF01080.17 EGG13664.1 - 1.1 7.9 3.0 2 7.1 3.0 1.3 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 EGG13664.1 - 1.2 8.8 7.5 28 4.4 5.3 2.8 2 1 0 2 2 2 0 AAA domain AIF_C PF14721.6 EGG13664.1 - 5.9 7.3 7.3 15 5.9 5.8 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CBS PF00571.28 EGG13665.1 - 7.4e-10 39.1 0.5 0.0023 18.3 0.1 3.9 4 0 0 4 4 4 3 CBS domain PseudoU_synth_2 PF00849.22 EGG13666.1 - 5.8e-27 94.7 8.4 2.7e-14 53.6 0.0 3.3 2 2 0 3 3 3 2 RNA pseudouridylate synthase DUF572 PF04502.13 EGG13666.1 - 1.2 8.7 27.9 2.5 7.6 2.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Ctr PF04145.15 EGG13667.1 - 3.6e-23 82.8 11.9 4.5e-22 79.3 11.9 1.9 1 1 0 1 1 1 1 Ctr copper transporter family Multi_Drug_Res PF00893.19 EGG13667.1 - 0.022 15.4 1.2 0.022 15.4 1.2 1.7 2 0 0 2 2 2 0 Small Multidrug Resistance protein Anoctamin PF04547.12 EGG13667.1 - 0.039 12.8 2.4 0.041 12.7 2.4 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel PDR_CDR PF06422.12 EGG13667.1 - 0.11 12.4 2.1 3.2 7.7 0.5 2.2 2 0 0 2 2 2 0 CDR ABC transporter NOA36 PF06524.12 EGG13667.1 - 0.2 10.9 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 NOA36 protein Ank_2 PF12796.7 EGG13669.1 - 6.5e-11 42.7 1.3 1.6e-06 28.6 0.1 4.9 4 1 1 5 5 5 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG13669.1 - 1.7e-06 28.4 0.1 0.015 15.8 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG13669.1 - 0.00012 22.2 0.3 0.78 10.1 0.1 3.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG13669.1 - 0.047 14.3 2.9 30 5.6 0.0 5.3 6 0 0 6 6 6 0 Ankyrin repeat NmrA PF05368.13 EGG13670.1 - 6e-51 173.2 1.1 7.2e-51 173.0 1.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGG13670.1 - 3.8e-14 53.0 0.1 6.8e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 EGG13670.1 - 6.8e-05 23.0 0.1 0.0067 16.6 0.0 2.4 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 EGG13670.1 - 0.00025 21.3 0.0 0.00052 20.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UPF0254 PF06787.11 EGG13670.1 - 0.0047 16.7 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0254) Epimerase PF01370.21 EGG13670.1 - 0.0054 16.2 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EGG13670.1 - 0.13 12.7 0.1 0.33 11.4 0.1 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EGG13670.1 - 0.15 12.0 0.1 0.66 9.9 0.0 2.0 2 0 0 2 2 2 0 KR domain NmrA PF05368.13 EGG13671.1 - 1.5e-51 175.3 0.5 1.8e-51 175.0 0.5 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGG13671.1 - 4.6e-14 52.7 0.0 6.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EGG13671.1 - 0.0003 21.1 0.0 0.00054 20.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EGG13671.1 - 0.00084 19.5 0.1 0.0076 16.4 0.0 2.2 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus UPF0254 PF06787.11 EGG13671.1 - 0.0029 17.4 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0254) Epimerase PF01370.21 EGG13671.1 - 0.0041 16.6 0.0 0.0089 15.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EGG13671.1 - 0.13 12.8 0.1 0.33 11.4 0.1 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Patatin PF01734.22 EGG13672.1 - 5.1e-17 62.7 9.5 4.7e-16 59.6 6.6 2.8 2 1 0 2 2 2 1 Patatin-like phospholipase ETRAMP PF09716.10 EGG13672.1 - 0.87 9.7 7.3 2 8.5 7.3 1.7 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) RAMP4 PF06624.12 EGG13673.1 - 0.065 13.3 0.2 0.065 13.3 0.2 2.3 3 0 0 3 3 3 0 Ribosome associated membrane protein RAMP4 VWA_2 PF13519.6 EGG13674.1 - 0.00026 21.6 0.0 0.00079 20.1 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_beta PF00362.18 EGG13674.1 - 0.0014 18.3 0.0 0.091 12.4 0.1 2.4 2 0 0 2 2 2 1 Integrin beta chain VWA domain DDRGK PF09756.9 EGG13674.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 DDRGK domain Pkinase PF00069.25 EGG13677.1 - 8e-33 113.9 0.7 6.5e-30 104.4 0.2 3.0 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13677.1 - 9.2e-21 74.3 0.1 5.6e-20 71.7 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG13677.1 - 2.3e-06 27.2 0.0 4.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGG13677.1 - 0.0024 16.7 0.0 0.0032 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGG13677.1 - 0.21 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cullin_Nedd8 PF10557.9 EGG13677.1 - 0.37 10.9 1.8 15 5.7 0.1 2.6 2 0 0 2 2 2 0 Cullin protein neddylation domain Pkinase PF00069.25 EGG13678.1 - 2.9e-63 213.7 2.7 6.8e-38 130.5 0.1 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13678.1 - 6.7e-51 173.0 0.1 5.9e-28 97.8 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 EGG13678.1 - 1.4e-05 24.5 0.2 0.0084 15.5 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGG13678.1 - 5.6e-05 22.1 0.1 0.0032 16.3 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 EGG13678.1 - 0.0001 21.4 0.1 0.075 12.0 0.0 2.4 2 1 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 EGG13678.1 - 0.0024 17.8 0.0 0.31 10.9 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG13678.1 - 0.007 15.7 2.4 0.032 13.6 0.1 3.0 3 1 0 3 3 3 1 Kinase-like RIO1 PF01163.22 EGG13678.1 - 0.056 13.0 1.1 0.08 12.5 0.2 1.7 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 EGG13679.1 - 4.8e-07 29.4 0.0 9.2e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13679.1 - 0.077 12.3 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein tyrosine kinase MreB_Mbl PF06723.13 EGG13679.1 - 0.12 11.2 0.0 6.7 5.4 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Pkinase PF00069.25 EGG13680.1 - 7.6e-48 163.2 0.0 9.9e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13680.1 - 1.4e-31 109.8 0.0 1.9e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG13680.1 - 0.00078 18.3 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGG13680.1 - 0.001 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGG13680.1 - 0.013 14.8 0.1 0.091 12.1 0.1 2.2 2 1 0 2 2 2 0 Kinase-like FTA2 PF13095.6 EGG13680.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PIP49_C PF12260.8 EGG13680.1 - 0.45 10.1 0.0 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Pkinase PF00069.25 EGG13681.1 - 8.6e-43 146.6 0.0 1.1e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13681.1 - 3e-26 92.3 0.0 4.1e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGG13681.1 - 0.0001 21.8 0.1 0.00016 21.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG13681.1 - 0.0045 16.9 0.1 0.6 10.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 EGG13681.1 - 0.053 13.1 0.1 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGG13681.1 - 0.12 11.7 0.3 1.1 8.5 0.2 2.1 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 EGG13681.1 - 0.13 11.7 0.2 0.25 10.8 0.2 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 EGG13682.1 - 2.5e-73 246.7 12.6 3.2e-44 151.3 1.4 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13682.1 - 1.8e-49 168.4 3.2 1e-25 90.5 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EGG13682.1 - 6.1e-08 32.3 0.0 0.0059 16.0 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGG13682.1 - 2.4e-07 29.9 4.2 0.002 17.0 0.7 2.3 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 EGG13682.1 - 4.2e-06 26.3 0.1 0.00068 19.0 0.0 2.8 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 EGG13682.1 - 0.00015 21.8 0.3 1.4 8.8 0.1 3.4 2 2 2 4 4 4 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EGG13682.1 - 0.0073 15.8 2.1 3.4 7.1 0.1 3.0 3 0 0 3 3 3 2 PhoP regulatory network protein YrbL FTA2 PF13095.6 EGG13682.1 - 0.085 12.5 4.2 2.3 7.8 0.1 3.5 4 0 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 DUF1554 PF07588.11 EGG13683.1 - 0.11 12.3 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1554) Pkinase PF00069.25 EGG13684.1 - 2.5e-27 95.9 0.3 7.6e-27 94.3 0.2 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13684.1 - 2.5e-21 76.1 0.0 4.3e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG13684.1 - 1.4e-05 24.1 0.0 2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGG13684.1 - 0.017 14.7 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGG13684.1 - 0.049 13.6 0.0 0.15 11.9 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Integrase_H2C2 PF17921.1 EGG13685.1 - 1.6e-10 40.9 0.0 2.5e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain AT_hook PF02178.19 EGG13685.1 - 0.00028 20.4 12.3 0.063 13.2 1.9 2.9 2 0 0 2 2 2 2 AT hook motif Mucin PF01456.17 EGG13685.1 - 0.044 13.8 8.4 0.07 13.1 8.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 EGG13685.1 - 0.3 11.1 5.5 0.46 10.5 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TLP-20 PF06088.11 EGG13685.1 - 1.3 8.9 13.3 0.08 12.8 4.8 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DTHCT PF08070.11 EGG13685.1 - 2.5 8.9 18.8 6.4 7.6 14.9 3.1 2 1 0 2 2 2 0 DTHCT (NUC029) region CDC45 PF02724.14 EGG13685.1 - 3 6.0 14.0 0.071 11.4 7.8 1.4 2 0 0 2 2 2 0 CDC45-like protein RRN3 PF05327.11 EGG13685.1 - 3.9 5.9 11.2 0.65 8.5 7.3 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 GP67 PF17634.2 EGG13685.1 - 8.8 6.8 22.2 23 5.5 22.2 1.7 1 0 0 1 1 1 0 Gene product 67 DUF4083 PF13314.6 EGG13686.1 - 0.02 14.8 0.4 0.081 12.9 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) HBB PF06777.11 EGG13686.1 - 0.027 14.2 0.1 0.073 12.8 0.1 1.7 1 0 0 1 1 1 0 Helical and beta-bridge domain TIP120 PF08623.10 EGG13686.1 - 0.11 12.2 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) DUF3439 PF11921.8 EGG13686.1 - 2.5 8.1 30.7 2 8.4 5.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) VWA_2 PF13519.6 EGG13687.1 - 0.00089 19.9 0.0 0.0033 18.1 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Peptidase_M22 PF00814.25 EGG13687.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family DUF577 PF04510.12 EGG13687.1 - 0.16 11.8 0.5 0.58 10.0 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF577) MIEAP PF16026.5 EGG13688.1 - 0.0059 16.8 0.0 0.0059 16.8 0.0 2.9 3 1 0 3 3 3 1 Mitochondria-eating protein DUF4407 PF14362.6 EGG13688.1 - 0.046 13.1 9.4 0.093 12.1 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lzipper-MIP1 PF14389.6 EGG13688.1 - 0.062 13.6 5.6 0.094 13.0 0.7 3.2 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 LPP PF04728.13 EGG13688.1 - 0.086 13.2 0.4 0.086 13.2 0.4 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF2935 PF11155.8 EGG13688.1 - 0.14 12.4 7.1 0.039 14.3 2.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) HALZ PF02183.18 EGG13688.1 - 0.15 12.3 6.2 0.15 12.3 1.4 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Packaging_FI PF14000.6 EGG13688.1 - 0.17 12.3 3.0 2.1 8.8 0.0 2.8 2 2 1 3 3 3 0 DNA packaging protein FI TMF_TATA_bd PF12325.8 EGG13688.1 - 0.26 11.5 10.1 0.3 11.3 5.7 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CtIP_N PF10482.9 EGG13688.1 - 0.64 10.1 10.4 0.49 10.5 0.3 3.2 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain SKA2 PF16740.5 EGG13688.1 - 1.8 8.4 11.0 1.5 8.6 1.0 3.1 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Spc7 PF08317.11 EGG13688.1 - 2.7 6.8 20.2 0.31 9.9 6.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 EGG13688.1 - 6.7 6.6 16.4 1.5 8.6 1.5 3.7 2 2 1 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 EGG13689.1 - 0.014 14.8 3.7 0.017 14.5 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4711 PF15829.5 EGG13689.1 - 0.014 15.3 0.1 0.018 15.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) Rop-like PF05082.13 EGG13689.1 - 0.027 14.3 0.7 0.05 13.4 0.7 1.4 1 0 0 1 1 1 0 Rop-like DFF-C PF09033.10 EGG13689.1 - 0.031 14.2 7.0 0.043 13.7 7.0 1.2 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain DUF5401 PF17380.2 EGG13689.1 - 0.48 8.4 10.8 0.61 8.1 10.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) PBP1_TM PF14812.6 EGG13689.1 - 0.84 10.1 6.1 1.5 9.3 4.9 1.9 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3899 PF13038.6 EGG13689.1 - 2.3 8.8 4.7 7.8 7.1 4.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) TMCO5 PF14992.6 EGG13689.1 - 2.5 7.6 13.4 5.1 6.6 2.4 2.0 1 1 1 2 2 2 0 TMCO5 family DUF2956 PF11169.8 EGG13689.1 - 2.9 8.1 8.7 11 6.3 8.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2956) ALMT PF11744.8 EGG13689.1 - 3.7 6.3 7.2 4.4 6.0 7.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter F-box-like PF12937.7 EGG13690.1 - 0.037 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 F-box-like HSP70 PF00012.20 EGG13691.1 - 0.0042 15.3 0.0 0.0061 14.8 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 EGG13692.1 - 8e-15 54.1 0.5 1.5e-07 30.0 0.1 4.0 4 1 0 5 5 5 2 Hsp70 protein LepB_N PF18640.1 EGG13692.1 - 0.025 14.2 0.0 0.64 9.6 0.0 2.5 2 0 0 2 2 2 0 LepB N-terminal domain Methyltransf_15 PF09445.10 EGG13693.1 - 5.6e-35 120.3 0.0 9.9e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 EGG13693.1 - 9.5e-07 28.6 0.1 3.2e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 EGG13693.1 - 0.00025 20.8 0.1 0.00067 19.4 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 EGG13693.1 - 0.00083 20.0 0.0 0.0018 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EGG13693.1 - 0.0015 18.3 0.2 0.0032 17.3 0.2 1.7 1 1 0 1 1 1 1 Met-10+ like-protein CobT_C PF11775.8 EGG13693.1 - 0.066 12.8 0.7 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain Methyltransf_11 PF08241.12 EGG13693.1 - 0.14 12.8 0.0 0.45 11.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain UPF0086 PF01868.16 EGG13694.1 - 4.3e-14 52.2 0.0 8.3e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 AAA_11 PF13086.6 EGG13695.1 - 0.061 13.1 26.3 0.22 11.3 7.3 2.4 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 EGG13695.1 - 0.4 10.2 32.4 0.046 13.3 11.1 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Activator_LAG-3 PF11498.8 EGG13695.1 - 1 8.2 103.6 0.023 13.7 46.8 2.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Neur_chan_memb PF02932.16 EGG13695.1 - 2.9 7.9 25.6 0.99 9.4 5.0 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RNA_pol_Rpc4 PF05132.14 EGG13696.1 - 7.6e-21 75.1 2.8 9.6e-21 74.8 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase III RPC4 DDA1 PF10172.9 EGG13697.1 - 0.00047 20.4 0.1 0.00047 20.4 0.1 2.8 3 1 0 3 3 3 1 Det1 complexing ubiquitin ligase Di19_C PF14571.6 EGG13697.1 - 0.014 15.9 2.9 0.014 15.9 2.9 2.8 1 1 1 3 3 3 0 Stress-induced protein Di19, C-terminal FAM176 PF14851.6 EGG13697.1 - 6.5 6.4 6.9 10 5.7 6.9 1.4 1 0 0 1 1 1 0 FAM176 family SAGA-Tad1 PF12767.7 EGG13697.1 - 7.7 6.2 14.1 1.7 8.4 11.1 1.4 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DOMON PF03351.17 EGG13698.1 - 9.8e-16 58.1 0.1 1.8e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 EGG13698.1 - 5.9e-10 39.4 18.0 1.4e-09 38.2 18.0 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 EGG13698.1 - 0.36 11.0 10.2 0.084 13.0 4.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) GRAB PF10375.9 EGG13698.1 - 1.2 9.2 3.0 2.2 8.3 3.0 1.5 1 0 0 1 1 1 0 GRIP-related Arf-binding domain bZIP_1 PF00170.21 EGG13699.1 - 7.4e-09 35.6 9.9 7.4e-09 35.6 9.9 2.5 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGG13699.1 - 0.00012 22.0 9.5 0.00012 22.0 9.5 2.8 3 0 0 3 3 3 1 Basic region leucine zipper SUIM_assoc PF16619.5 EGG13699.1 - 0.00066 19.7 0.0 0.00066 19.7 0.0 4.8 4 2 1 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 DUF484 PF04340.12 EGG13699.1 - 0.046 13.4 0.9 0.093 12.4 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF484 DUF4407 PF14362.6 EGG13699.1 - 6.1 6.1 11.0 0.98 8.7 6.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ASF1_hist_chap PF04729.13 EGG13700.1 - 0.00016 21.7 0.1 0.00025 21.0 0.1 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone RNase_HII PF01351.18 EGG13701.1 - 1.1e-34 120.0 11.1 2.5e-19 69.9 0.1 3.4 3 1 0 4 4 4 2 Ribonuclease HII Abhydro_lipase PF04083.16 EGG13702.1 - 3.5e-19 68.1 0.0 1.1e-18 66.5 0.0 1.9 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGG13702.1 - 9.3e-11 41.9 0.1 1.5e-10 41.2 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold LRR_9 PF14580.6 EGG13702.1 - 4.9 6.6 7.3 8.4 5.9 7.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeat THF_DHG_CYH PF00763.23 EGG13704.1 - 1.2e-21 77.2 0.1 3e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EGG13704.1 - 4e-16 58.8 1.2 7.9e-14 51.3 1.2 3.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DpaA_N PF16924.5 EGG13704.1 - 0.039 14.1 0.0 0.56 10.3 0.0 2.3 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain HECT PF00632.25 EGG13705.1 - 4.8e-82 275.9 0.3 7.9e-82 275.2 0.3 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 EGG13705.1 - 0.00075 19.4 5.4 6.4 7.0 0.0 5.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Usp PF00582.26 EGG13705.1 - 0.078 13.5 2.4 0.69 10.4 0.0 2.6 2 0 0 2 2 2 0 Universal stress protein family HEAT_EZ PF13513.6 EGG13705.1 - 0.15 12.6 0.2 0.69 10.5 0.0 2.3 2 0 0 2 2 2 0 HEAT-like repeat Importin_rep_6 PF18829.1 EGG13705.1 - 1.6 8.9 7.7 0.068 13.3 0.5 2.5 2 0 0 2 2 2 0 Importin repeat 6 DAP3 PF10236.9 EGG13706.1 - 0.003 16.8 0.0 0.013 14.6 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 ResIII PF04851.15 EGG13706.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EGG13706.1 - 0.2 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein EXS PF03124.14 EGG13707.1 - 1.2e-88 297.6 31.6 1.6e-88 297.2 31.6 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EGG13707.1 - 2.5e-42 146.2 16.7 2.5e-42 146.2 16.7 2.5 2 1 0 2 2 2 1 SPX domain Chordopox_E11 PF06138.12 EGG13707.1 - 0.1 12.9 1.0 0.25 11.6 1.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus E11 protein zf-C2H2_jaz PF12171.8 EGG13709.1 - 7.8e-07 29.2 2.4 8.3e-07 29.1 0.8 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG13709.1 - 0.0011 19.3 1.3 0.0026 18.1 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGG13709.1 - 0.0038 17.5 0.2 0.0038 17.5 0.2 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 EGG13709.1 - 0.027 14.4 0.4 0.027 14.4 0.4 2.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Mucin PF01456.17 EGG13709.1 - 3.8 7.5 10.0 4.1 7.4 7.7 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Ank_2 PF12796.7 EGG13710.1 - 8.1e-08 32.8 0.0 2.5e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG13710.1 - 3.5e-07 30.4 0.0 1.8e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGG13710.1 - 2e-05 24.8 0.1 0.0062 16.9 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGG13710.1 - 3.9e-05 24.1 0.1 0.003 18.1 0.0 3.4 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG13710.1 - 0.00097 19.4 0.1 0.098 13.3 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeat UPF0552 PF10574.9 EGG13710.1 - 0.11 11.8 0.1 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 Arp2/3-interacting proteins Arpin HlyIII PF03006.20 EGG13711.1 - 8.4e-25 87.8 19.4 2.7e-13 50.1 1.8 2.1 1 1 1 2 2 2 2 Haemolysin-III related GWT1 PF06423.12 EGG13711.1 - 0.17 12.0 8.4 0.053 13.7 4.8 2.1 1 1 1 2 2 2 0 GWT1 MIEAP PF16026.5 EGG13712.1 - 0.0015 18.8 0.1 0.0015 18.8 0.1 4.2 2 1 1 4 4 4 1 Mitochondria-eating protein HSBP1 PF06825.12 EGG13712.1 - 0.094 12.6 11.8 0.36 10.7 0.1 4.3 3 2 1 4 4 4 0 Heat shock factor binding protein 1 TMF_TATA_bd PF12325.8 EGG13712.1 - 0.16 12.2 17.3 9.8 6.4 7.8 3.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding NYD-SP28_assoc PF14775.6 EGG13712.1 - 0.25 11.5 3.5 1 9.5 3.5 2.1 1 0 0 1 1 1 0 Sperm tail C-terminal domain RasGAP_C PF03836.15 EGG13712.1 - 5 7.3 26.3 2 8.6 13.3 3.5 1 1 1 2 2 2 0 RasGAP C-terminus Mucin PF01456.17 EGG13712.1 - 8.9 6.3 24.7 10 6.1 5.4 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein HSP70 PF00012.20 EGG13713.1 - 4.1e-06 25.3 0.1 2.1e-05 23.0 0.0 2.0 3 0 0 3 3 3 1 Hsp70 protein DUF1554 PF07588.11 EGG13713.1 - 0.041 13.7 0.0 0.41 10.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1554) VWA PF00092.28 EGG13713.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain ATG16 PF08614.11 EGG13714.1 - 0.0043 17.3 10.9 0.0092 16.2 10.8 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Cortex-I_coil PF09304.10 EGG13714.1 - 0.005 17.0 1.9 0.005 17.0 1.9 2.3 1 1 1 2 2 2 1 Cortexillin I, coiled coil TMF_DNA_bd PF12329.8 EGG13714.1 - 0.018 15.0 24.0 0.11 12.5 3.4 4.1 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding zf-C4H2 PF10146.9 EGG13714.1 - 0.033 14.5 12.0 0.064 13.6 12.0 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein Taxilin PF09728.9 EGG13714.1 - 0.042 13.0 17.6 0.024 13.8 4.8 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Cep57_CLD_2 PF14197.6 EGG13714.1 - 0.045 13.8 5.6 3.9 7.6 1.5 2.8 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF4618 PF15397.6 EGG13714.1 - 0.096 12.1 17.0 0.11 11.9 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF3450 PF11932.8 EGG13714.1 - 0.1 11.9 18.0 0.41 9.9 8.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 EGG13714.1 - 0.1 12.9 14.6 0.22 11.9 3.1 3.2 2 1 1 3 3 3 0 Csm1 N-terminal domain MbeD_MobD PF04899.12 EGG13714.1 - 0.12 12.5 6.6 4.5 7.5 0.8 3.3 1 1 2 3 3 3 0 MbeD/MobD like DivIC PF04977.15 EGG13714.1 - 0.12 12.1 16.9 0.56 10.0 1.3 3.6 1 1 2 3 3 3 0 Septum formation initiator SlyX PF04102.12 EGG13714.1 - 0.14 12.8 9.3 1.1 9.9 1.6 3.2 1 1 2 3 3 3 0 SlyX Cnn_1N PF07989.11 EGG13714.1 - 0.14 12.3 17.7 3.1e+03 -1.6 17.7 2.7 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 MerR-DNA-bind PF09278.11 EGG13714.1 - 0.14 12.7 0.8 3.2 8.4 0.3 2.4 2 0 0 2 2 2 0 MerR, DNA binding KASH_CCD PF14662.6 EGG13714.1 - 0.17 11.7 17.5 0.2 11.5 5.3 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 EGG13714.1 - 0.17 12.0 20.6 1.3 9.1 8.0 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.13 EGG13714.1 - 0.18 11.9 16.3 0.69 10.0 5.5 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FAM53 PF15242.6 EGG13714.1 - 0.26 11.1 2.0 0.33 10.7 2.0 1.2 1 0 0 1 1 1 0 Family of FAM53 HSBP1 PF06825.12 EGG13714.1 - 0.27 11.1 8.8 0.85 9.5 0.1 4.5 3 1 1 4 4 4 0 Heat shock factor binding protein 1 TolA_bind_tri PF16331.5 EGG13714.1 - 0.32 11.1 12.9 1.1 9.3 3.3 3.0 2 1 1 3 3 3 0 TolA binding protein trimerisation bZIP_2 PF07716.15 EGG13714.1 - 0.34 11.0 8.6 10 6.3 0.1 3.9 2 2 2 4 4 4 0 Basic region leucine zipper YabA PF06156.13 EGG13714.1 - 0.49 11.1 18.0 0.56 10.9 5.3 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Tropomyosin_1 PF12718.7 EGG13714.1 - 0.69 10.1 14.5 0.3 11.2 1.9 2.7 1 1 0 2 2 2 0 Tropomyosin like Tho2 PF11262.8 EGG13714.1 - 0.81 8.8 15.0 1.8 7.7 4.5 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 EGG13714.1 - 0.86 8.9 9.8 1.3 8.3 9.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF848 PF05852.11 EGG13714.1 - 0.87 9.7 7.8 0.96 9.6 5.1 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) APG6_N PF17675.1 EGG13714.1 - 0.94 10.0 11.5 2.6 8.6 2.8 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region FlaC_arch PF05377.11 EGG13714.1 - 0.94 9.9 11.9 8 6.9 2.8 3.9 2 2 0 3 3 3 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 EGG13714.1 - 1 9.8 14.8 1.8 9.0 3.8 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF2935 PF11155.8 EGG13714.1 - 1.3 9.4 7.7 47 4.3 7.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) TSC22 PF01166.18 EGG13714.1 - 2.2 8.6 7.2 3.5 8.0 0.2 3.4 2 2 1 3 3 3 0 TSC-22/dip/bun family bZIP_1 PF00170.21 EGG13714.1 - 3.4 7.8 15.0 6.1 7.0 1.1 3.9 2 2 3 5 5 5 0 bZIP transcription factor JIP_LZII PF16471.5 EGG13714.1 - 5.2 7.3 13.7 7.5 6.8 3.1 2.6 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II DUF948 PF06103.11 EGG13714.1 - 5.5 7.3 10.8 2.9 8.2 1.4 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BRE1 PF08647.11 EGG13714.1 - 6.2 7.0 21.8 0.47 10.6 8.8 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Med9 PF07544.13 EGG13714.1 - 7.7 6.7 12.6 4.8 7.3 5.8 3.5 1 1 1 2 2 1 0 RNA polymerase II transcription mediator complex subunit 9 ZapB PF06005.12 EGG13714.1 - 8.3 6.9 14.6 0.81 10.2 4.1 2.7 1 1 1 2 2 2 0 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 EGG13714.1 - 9.7 6.4 13.2 39 4.4 11.8 2.2 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Pkinase PF00069.25 EGG13715.1 - 1.8e-37 129.2 1.4 2.2e-37 128.9 1.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13715.1 - 9.9e-24 84.0 0.9 1.8e-23 83.2 0.9 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG13715.1 - 5.4e-06 25.9 0.1 4.3e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG13715.1 - 9.6e-06 25.1 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGG13715.1 - 0.00043 19.2 0.1 0.00066 18.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGG13715.1 - 0.00088 18.9 1.5 0.0013 18.3 1.4 1.4 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 EGG13715.1 - 0.15 11.9 0.0 0.62 9.9 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family ILEI PF15711.5 EGG13716.1 - 3.3e-16 59.5 0.0 5.3e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Interleukin-like EMT inducer CDO_I PF05995.12 EGG13717.1 - 3e-29 101.5 0.0 4.1e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I La PF05383.17 EGG13718.1 - 4.4e-23 81.1 0.2 9.3e-23 80.1 0.2 1.6 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 EGG13718.1 - 1.2e-18 67.0 5.5 8.7e-18 64.3 0.4 2.7 2 1 0 2 2 2 2 RNA binding motif RRM_1 PF00076.22 EGG13718.1 - 8.8e-08 31.9 0.8 0.001 18.9 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ComS PF17584.2 EGG13720.1 - 0.012 15.1 0.2 1.3 8.6 0.0 2.2 1 1 1 2 2 2 0 Bacillus competence protein S P2X_receptor PF00864.19 EGG13721.1 - 7.4e-17 61.5 0.9 3.1e-08 33.1 0.2 2.5 2 1 0 2 2 2 2 ATP P2X receptor SpoIIIAH PF12685.7 EGG13721.1 - 0.015 15.2 1.2 0.027 14.3 1.2 1.4 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF4834 PF16118.5 EGG13721.1 - 0.029 15.3 0.4 0.029 15.3 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Hid1 PF12722.7 EGG13721.1 - 0.16 10.0 2.9 0.21 9.7 2.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EVI2A PF05399.11 EGG13721.1 - 0.39 10.3 6.7 0.71 9.4 6.7 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Presenilin PF01080.17 EGG13721.1 - 5.2 5.7 6.5 9.9 4.8 6.5 1.4 1 0 0 1 1 1 0 Presenilin Coilin_N PF15862.5 EGG13721.1 - 7.7 6.3 8.6 3.6 7.4 3.6 2.1 2 0 0 2 2 2 0 Coilin N-terminus TPR_1 PF00515.28 EGG13722.1 - 4.5e-24 83.2 7.5 3.2e-05 23.5 0.0 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGG13722.1 - 1.3e-23 81.1 8.5 0.00015 21.7 0.0 9.3 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG13722.1 - 1.5e-17 62.2 6.8 0.00065 19.7 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGG13722.1 - 5.3e-15 55.5 1.5 1.5e-07 31.6 0.1 7.0 4 3 3 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG13722.1 - 7.2e-15 55.0 25.7 5.6e-08 32.9 0.6 6.8 4 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGG13722.1 - 1e-14 53.4 0.1 0.0023 17.8 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGG13722.1 - 1.9e-11 43.5 0.7 0.17 12.3 0.1 5.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG13722.1 - 3.9e-09 36.9 0.4 0.53 10.8 0.0 6.3 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG13722.1 - 1.7e-08 34.5 0.0 3 8.9 0.0 6.5 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG13722.1 - 2.3e-08 33.6 11.0 0.0027 17.3 0.0 6.4 6 2 2 8 8 8 2 TPR repeat TPR_10 PF13374.6 EGG13722.1 - 9.2e-08 31.7 0.1 0.068 13.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG13722.1 - 1.3e-07 32.1 0.0 0.028 15.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG13722.1 - 5e-07 29.9 4.0 0.38 11.5 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_3 PF07720.12 EGG13722.1 - 0.0013 18.6 12.5 0.0081 16.1 0.3 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC8 PF04049.13 EGG13722.1 - 0.0055 16.8 4.4 0.035 14.2 0.1 3.0 3 1 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 KLRAQ PF10205.9 EGG13722.1 - 0.064 13.5 0.4 0.21 11.8 0.1 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Sec1 PF00995.23 EGG13723.1 - 2.4e-116 390.3 7.5 2.8e-116 390.1 7.5 1.0 1 0 0 1 1 1 1 Sec1 family Cyt-b5 PF00173.28 EGG13724.1 - 1.9e-27 95.2 0.3 5.1e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DUF295 PF03478.18 EGG13724.1 - 0.031 13.8 1.1 15 5.3 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF295) Gloverin PF10793.9 EGG13724.1 - 0.055 13.3 0.1 0.19 11.6 0.0 1.8 1 1 1 2 2 2 0 Gloverin-like protein Tir_receptor_N PF07490.11 EGG13724.1 - 0.36 10.6 5.4 0.56 10.0 5.4 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus FSA_C PF10479.9 EGG13724.1 - 0.42 8.7 9.0 0.52 8.4 9.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 EGG13724.1 - 0.49 10.4 14.7 0.98 9.4 14.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 EGG13724.1 - 0.61 8.2 17.9 0.77 7.9 17.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.9 EGG13724.1 - 0.93 8.0 5.7 0.98 7.9 5.7 1.1 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 EGG13724.1 - 2.4 7.7 12.8 4.4 6.8 12.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF179 PF02622.15 EGG13725.1 - 1.9e-29 102.7 0.0 3.3e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 ALMT PF11744.8 EGG13725.1 - 0.86 8.4 3.2 1.3 7.8 3.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4175 PF13779.6 EGG13725.1 - 0.99 7.2 3.1 1.4 6.7 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SKA1 PF07160.12 EGG13725.1 - 1.5 8.7 5.8 0.26 11.1 2.3 1.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 AJAP1_PANP_C PF15298.6 EGG13727.1 - 1.7 8.8 19.2 0.15 12.3 13.6 1.8 1 1 1 2 2 2 0 AJAP1/PANP C-terminus tRNA-synt_2 PF00152.20 EGG13728.1 - 2e-93 312.9 0.2 2.8e-93 312.4 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.15 EGG13728.1 - 4e-47 160.2 0.4 4e-47 160.2 0.4 1.6 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.25 EGG13728.1 - 1.6e-09 37.6 0.0 3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ribosomal_S8e PF01201.22 EGG13729.1 - 6.1e-48 162.5 5.2 6.1e-48 162.5 5.2 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e TPR_1 PF00515.28 EGG13730.1 - 1e-31 107.4 28.4 1.5e-08 34.1 0.2 8.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGG13730.1 - 3.6e-30 101.6 24.8 5.5e-05 23.0 0.1 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat DnaJ PF00226.31 EGG13730.1 - 4.3e-25 87.6 3.3 1.6e-24 85.8 3.3 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.6 EGG13730.1 - 7.5e-17 61.7 3.5 0.0003 21.4 0.1 5.5 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG13730.1 - 2.6e-16 58.4 21.3 0.00043 20.3 0.1 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGG13730.1 - 1.8e-14 53.1 14.7 0.0061 16.2 0.0 7.5 4 2 3 7 7 7 4 TPR repeat TPR_19 PF14559.6 EGG13730.1 - 3.8e-13 49.8 19.0 0.0017 18.9 0.6 6.8 4 2 2 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGG13730.1 - 5e-10 38.7 3.2 0.56 10.4 0.2 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG13730.1 - 1.9e-09 37.2 13.3 4.5e-05 23.5 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGG13730.1 - 6.1e-09 35.9 1.2 0.00022 21.3 0.5 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG13730.1 - 2e-08 34.4 13.2 4.2e-05 23.7 0.1 5.6 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG13730.1 - 2.4e-08 34.1 4.3 1.6 9.8 0.0 6.7 4 1 2 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG13730.1 - 0.00069 19.8 16.3 0.66 10.2 2.0 5.4 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 HrpB1_HrpK PF09613.10 EGG13730.1 - 0.00095 18.8 0.3 1 9.0 0.1 3.8 4 0 0 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 EGG13730.1 - 0.037 14.4 12.2 0.39 11.1 0.9 4.5 2 2 2 4 4 4 0 Tetratricopeptide repeat PfkB PF00294.24 EGG13730.1 - 0.11 11.7 0.9 0.28 10.5 0.1 2.0 2 0 0 2 2 2 0 pfkB family carbohydrate kinase TPR_10 PF13374.6 EGG13730.1 - 0.12 12.3 6.5 4.7 7.2 0.4 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 EGG13730.1 - 0.52 10.4 9.7 4.5 7.4 0.5 4.5 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain DNA_pol3_alpha PF07733.12 EGG13730.1 - 6.5 6.2 7.5 2.8 7.4 1.4 2.7 3 0 0 3 3 3 0 Bacterial DNA polymerase III alpha NTPase domain zf-UBR PF02207.20 EGG13731.1 - 0.00054 20.1 6.2 0.00054 20.1 6.2 2.7 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-RING_5 PF14634.6 EGG13731.1 - 0.0031 17.4 3.6 0.0031 17.4 3.6 3.2 3 0 0 3 3 3 1 zinc-RING finger domain DUF3439 PF11921.8 EGG13731.1 - 0.76 9.7 4.0 2.4 8.2 4.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGG13731.1 - 0.94 9.5 13.3 0.023 14.7 5.4 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-C3HC4 PF00097.25 EGG13731.1 - 2 8.4 9.2 0.2 11.5 3.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DDHD PF02862.17 EGG13731.1 - 3.8 7.6 6.1 6.7 6.8 4.5 2.3 2 0 0 2 2 2 0 DDHD domain zf-C2H2_2 PF12756.7 EGG13732.1 - 5.7e-39 132.5 19.1 4.3e-20 71.9 3.5 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EGG13732.1 - 1.5e-07 31.7 19.8 0.054 14.4 2.1 5.6 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGG13732.1 - 8.5e-06 25.9 4.6 8.5e-06 25.9 4.6 4.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG13732.1 - 5.5e-05 23.4 13.9 0.0044 17.4 3.7 3.3 3 0 0 3 3 2 2 Zinc-finger of C2H2 type zf-BED PF02892.15 EGG13732.1 - 0.00021 21.2 3.6 0.082 12.9 1.3 3.1 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_9 PF16293.5 EGG13732.1 - 0.00081 19.2 10.8 0.24 11.2 0.1 4.5 4 0 0 4 4 4 2 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 EGG13732.1 - 0.0022 18.3 20.1 0.33 11.3 0.1 5.4 5 0 0 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding DUF4187 PF13821.6 EGG13732.1 - 0.0031 17.2 6.1 9.2 6.1 0.1 4.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4187) zf-C2H2 PF00096.26 EGG13732.1 - 0.006 17.0 22.5 0.027 14.9 3.3 4.7 5 0 0 5 5 4 2 Zinc finger, C2H2 type UBZ_FAAP20 PF15750.5 EGG13732.1 - 0.056 13.4 2.4 0.45 10.5 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-C2H2_3rep PF18868.1 EGG13732.1 - 0.099 13.3 9.6 2.7 8.7 1.0 4.2 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 EGG13732.1 - 0.53 10.1 10.6 0.14 11.9 1.4 3.4 4 0 0 4 4 4 0 zinc-finger C2H2-type PyrI_C PF02748.15 EGG13732.1 - 1.2 9.1 10.4 0.24 11.3 0.5 3.5 4 0 0 4 4 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.6 EGG13732.1 - 3.8 7.6 10.1 5.1 7.2 2.9 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 EGG13732.1 - 4.2 7.9 14.9 1.3 9.6 0.6 4.3 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain DUF2225 PF09986.9 EGG13732.1 - 9.2 5.9 11.2 3.1 7.5 1.1 3.5 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) WD40 PF00400.32 EGG13733.1 - 9.7e-30 102.2 32.5 3.1e-07 31.0 1.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG13733.1 - 9.6e-18 64.3 3.1 0.00042 20.5 0.0 5.6 2 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG13733.1 - 1e-06 28.0 4.2 0.31 10.0 0.1 4.2 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGG13733.1 - 2.6e-06 27.5 0.3 0.0014 18.5 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 EGG13733.1 - 0.0005 19.1 1.5 2.6 6.9 0.1 3.5 2 1 2 4 4 4 3 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 EGG13733.1 - 0.0013 18.4 0.4 0.0035 17.0 0.1 1.8 1 1 1 2 2 2 2 PQQ-like domain PD40 PF07676.12 EGG13733.1 - 0.0052 16.7 2.3 1.2 9.2 0.1 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat PQQ PF01011.21 EGG13733.1 - 0.0085 16.0 0.3 0.18 11.8 0.1 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat Coatomer_WDAD PF04053.14 EGG13733.1 - 0.019 14.0 0.1 0.038 13.0 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region Cytochrom_D1 PF02239.16 EGG13733.1 - 0.023 13.3 0.3 0.11 11.0 0.1 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain DUF5046 PF16465.5 EGG13733.1 - 0.024 14.1 0.2 0.1 12.0 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) bZIP_1 PF00170.21 EGG13734.1 - 3.3e-11 43.1 6.7 1.3e-10 41.2 6.5 2.2 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EGG13734.1 - 2.8e-05 24.5 3.6 2.8e-05 24.5 3.6 2.5 3 0 0 3 3 3 1 bZIP Maf transcription factor bZIP_2 PF07716.15 EGG13734.1 - 3.2e-05 23.9 10.4 0.00053 20.0 10.4 2.6 1 1 0 1 1 1 1 Basic region leucine zipper Kelch_5 PF13854.6 EGG13735.1 - 6.7e-35 118.5 7.0 3.3e-07 30.2 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EGG13735.1 - 8.8e-34 114.8 3.5 6.5e-08 32.0 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EGG13735.1 - 2.8e-29 100.4 11.7 1.7e-06 28.1 0.1 6.6 4 1 2 6 6 6 5 Kelch motif Kelch_3 PF13415.6 EGG13735.1 - 8e-28 96.2 8.8 5.9e-06 26.4 0.1 6.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EGG13735.1 - 5.5e-22 76.8 16.8 0.0002 21.2 0.1 7.0 6 1 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 EGG13735.1 - 4.7e-21 74.5 10.3 4.8e-06 26.5 0.0 6.5 6 1 0 6 6 6 5 Galactose oxidase, central domain F-box-like PF12937.7 EGG13735.1 - 4.6e-05 23.2 0.3 0.00011 22.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGG13735.1 - 0.0011 18.8 0.6 0.0031 17.4 0.6 1.8 1 0 0 1 1 1 1 F-box domain NUMOD1 PF07453.13 EGG13735.1 - 0.032 14.5 1.4 0.12 12.6 0.3 2.4 2 0 0 2 2 2 0 NUMOD1 domain Fumble PF03630.14 EGG13736.1 - 2.8e-117 391.6 9.8 2.2e-116 388.7 1.3 3.0 2 2 1 3 3 3 2 Fumble DUF2405 PF10293.9 EGG13736.1 - 1.5 8.7 6.0 0.49 10.3 2.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2405) Ras PF00071.22 EGG13737.1 - 2.2e-48 163.9 0.2 8.4e-36 123.0 0.1 2.4 2 0 0 2 2 2 2 Ras family bMG10 PF17973.1 EGG13737.1 - 1.3e-22 80.4 0.0 4e-21 75.6 0.0 2.9 2 0 0 2 2 2 1 Bacterial Alpha-2-macroglobulin MG10 domain Roc PF08477.13 EGG13737.1 - 1.1e-16 61.1 0.0 2.9e-09 37.2 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase A2M_BRD PF07703.14 EGG13737.1 - 3.1e-15 56.8 0.7 1.3e-14 54.8 0.2 2.4 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain MG2 PF01835.19 EGG13737.1 - 4.9e-09 36.5 0.1 1.1e-05 25.8 0.0 3.6 3 0 0 3 3 3 2 MG2 domain A2M PF00207.22 EGG13737.1 - 7.2e-07 29.0 0.1 3.6e-06 26.7 0.1 2.2 1 0 0 1 1 1 1 Alpha-2-macroglobulin family Arf PF00025.21 EGG13737.1 - 3.5e-05 23.3 0.1 0.00032 20.2 0.0 2.3 1 1 1 2 2 2 1 ADP-ribosylation factor family bMG3 PF11974.8 EGG13737.1 - 0.0001 22.2 6.7 0.35 10.9 0.2 4.4 3 1 1 4 4 4 2 Bacterial alpha-2-macroglobulin MG3 domain RsgA_GTPase PF03193.16 EGG13737.1 - 0.0016 18.4 0.0 0.0054 16.7 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase TAFII28 PF04719.14 EGG13738.1 - 2e-33 114.3 0.2 2e-33 114.3 0.2 1.9 2 0 0 2 2 2 1 hTAFII28-like protein conserved region Mucin PF01456.17 EGG13738.1 - 0.24 11.4 14.9 0.58 10.1 14.9 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 EGG13738.1 - 2.1 8.3 12.8 3.7 7.6 12.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGG13738.1 - 4.5 5.3 15.7 6.1 4.9 15.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-CCHH PF10283.9 EGG13739.1 - 1.5e-12 47.3 3.3 2.7e-12 46.4 3.3 1.4 1 0 0 1 1 1 1 PBZ domain FHA_2 PF17913.1 EGG13739.1 - 7.6e-06 26.1 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain FHA PF00498.26 EGG13739.1 - 0.011 16.0 0.1 0.032 14.6 0.1 1.7 1 0 0 1 1 1 0 FHA domain Macro PF01661.21 EGG13739.1 - 0.057 13.5 0.2 0.15 12.1 0.1 1.8 1 1 0 1 1 1 0 Macro domain DEAD PF00270.29 EGG13740.1 - 3.1e-19 69.4 1.3 7.1e-19 68.2 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase RQC PF09382.10 EGG13740.1 - 1.3e-14 53.9 0.2 2.8e-14 52.9 0.2 1.5 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 EGG13740.1 - 3.4e-14 53.1 0.0 7.1e-12 45.7 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EGG13740.1 - 1.2e-12 48.3 3.5 4.3e-12 46.6 3.5 2.0 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 EGG13740.1 - 6.5e-07 29.3 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 HRDC domain TolA_bind_tri PF16331.5 EGG13740.1 - 0.0022 18.0 0.2 0.0061 16.6 0.2 1.7 1 0 0 1 1 1 1 TolA binding protein trimerisation adh_short PF00106.25 EGG13741.1 - 7.9e-32 110.3 1.0 1.4e-21 76.8 0.9 2.7 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG13741.1 - 2.7e-16 59.8 2.9 2.4e-14 53.4 0.4 3.0 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase bZIP_1 PF00170.21 EGG13741.1 - 3e-07 30.4 12.3 3e-07 30.4 12.3 2.1 2 0 0 2 2 2 1 bZIP transcription factor KR PF08659.10 EGG13741.1 - 1.2e-06 28.5 0.3 3.8e-06 26.9 0.3 1.8 1 1 0 1 1 1 1 KR domain bZIP_2 PF07716.15 EGG13741.1 - 1.8e-05 24.7 16.0 1.8e-05 24.7 16.0 3.4 4 0 0 4 4 4 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGG13741.1 - 6.7e-05 23.3 7.5 6.7e-05 23.3 7.5 3.4 3 0 0 3 3 3 1 bZIP Maf transcription factor Epimerase PF01370.21 EGG13741.1 - 0.066 12.7 1.3 0.29 10.6 1.3 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Vir_act_alpha_C PF10400.9 EGG13741.1 - 0.19 12.4 0.8 25 5.7 0.0 2.5 2 0 0 2 2 2 0 Virulence activator alpha C-term DUF4349 PF14257.6 EGG13741.1 - 4.3 6.7 12.1 1.7 8.0 0.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) DUF4140 PF13600.6 EGG13741.1 - 10 6.7 12.2 4 8.0 3.5 3.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PNRC PF15365.6 EGG13742.1 - 4.2e-08 32.8 3.3 4.2e-08 32.8 3.3 2.6 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif Presenilin PF01080.17 EGG13742.1 - 5.1 5.7 7.4 6.5 5.4 7.4 1.3 1 0 0 1 1 1 0 Presenilin DUF3085 PF11284.8 EGG13743.1 - 0.12 12.7 0.8 0.39 11.1 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3085) DUF4106 PF13388.6 EGG13743.1 - 0.56 9.4 16.5 0.7 9.1 16.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF1394 PF07159.12 EGG13744.1 - 3.2e-127 424.0 0.2 3.6e-127 423.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Complex1_LYR PF05347.15 EGG13745.1 - 1.2e-06 28.4 0.0 2.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF726 PF05277.12 EGG13746.1 - 4.8e-61 206.6 16.6 3.4e-40 138.0 6.2 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF726) VPS9 PF02204.18 EGG13746.1 - 2e-12 47.3 0.1 6.9e-12 45.5 0.1 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF45 PF01863.17 EGG13746.1 - 0.17 11.9 1.5 0.62 10.1 1.5 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF45 HTH_45 PF14947.6 EGG13747.1 - 0.077 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix V_ATPase_I PF01496.19 EGG13747.1 - 1.4 6.8 14.7 2 6.2 14.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GREB1 PF15782.5 EGG13747.1 - 4.1 4.4 17.4 4.4 4.3 17.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_23 PF13476.6 EGG13749.1 - 0.41 11.1 18.2 0.6 10.6 18.2 1.2 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 EGG13749.1 - 1.2 9.1 5.9 2.2 8.3 5.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GlpM PF06942.12 EGG13750.1 - 0.046 14.1 3.0 0.22 12.0 0.3 2.5 2 0 0 2 2 2 0 GlpM protein DAP_epimerase PF01678.19 EGG13752.1 - 5.7e-45 152.4 0.7 1.7e-25 89.6 0.1 3.8 3 2 0 3 3 3 2 Diaminopimelate epimerase DUF4501 PF14946.6 EGG13752.1 - 0.028 14.5 0.6 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) YolD PF08863.10 EGG13753.1 - 0.035 14.2 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 YolD-like protein SAP PF02037.27 EGG13754.1 - 2.8e-05 23.7 0.1 2.8e-05 23.7 0.1 2.1 3 0 0 3 3 3 1 SAP domain Dicty_REP PF05086.12 EGG13754.1 - 0.0059 14.7 19.9 0.0089 14.1 19.9 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Ish1 PF10281.9 EGG13754.1 - 0.044 14.1 0.7 0.15 12.4 0.7 2.0 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein PRESAN PF09687.10 EGG13754.1 - 4.1 8.0 13.4 6.8 7.3 2.5 2.8 2 1 0 2 2 2 0 Plasmodium RESA N-terminal FMN_dh PF01070.18 EGG13755.1 - 8.3e-133 442.7 0.0 9.5e-133 442.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EGG13755.1 - 3.4e-07 29.6 0.8 7.6e-07 28.4 0.8 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EGG13755.1 - 7.2e-07 28.9 0.6 1.1e-06 28.3 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 EGG13755.1 - 1.1e-06 28.1 1.4 0.0049 16.2 0.2 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EGG13755.1 - 0.00026 20.2 0.3 0.0036 16.4 0.3 2.2 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EGG13755.1 - 0.0011 18.3 0.2 0.0021 17.3 0.0 1.5 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 EGG13755.1 - 0.0024 17.1 0.6 0.0045 16.2 0.2 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase G3P_antiterm PF04309.12 EGG13755.1 - 0.0035 16.8 0.1 0.019 14.4 0.0 2.1 1 1 1 2 2 2 1 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 EGG13755.1 - 0.012 15.1 0.4 0.041 13.3 0.1 1.9 2 1 1 3 3 3 0 Histidine biosynthesis protein AAA PF00004.29 EGG13756.1 - 1.3e-51 174.4 0.3 7.7e-31 107.3 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG13756.1 - 1.5e-20 72.7 0.1 5.4e-13 48.5 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGG13756.1 - 2e-10 41.3 2.4 0.00032 21.1 0.0 4.5 3 2 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 EGG13756.1 - 3.3e-07 30.6 0.0 0.014 15.7 0.0 3.6 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.14 EGG13756.1 - 3.1e-06 27.2 0.0 0.011 15.7 0.0 3.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGG13756.1 - 1.9e-05 24.5 0.0 0.011 15.4 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EGG13756.1 - 5.3e-05 22.7 0.0 0.0024 17.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGG13756.1 - 8.7e-05 22.1 0.0 0.4 10.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region RuvB_N PF05496.12 EGG13756.1 - 0.00013 21.8 0.5 0.0018 18.0 0.0 2.9 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGG13756.1 - 0.00014 22.1 0.0 0.0009 19.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EGG13756.1 - 0.00031 20.9 0.0 0.31 11.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EGG13756.1 - 0.00033 21.0 0.1 0.33 11.3 0.0 3.0 2 1 0 2 2 2 1 RNA helicase TIP49 PF06068.13 EGG13756.1 - 0.00038 19.8 0.0 0.0039 16.4 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain NB-ARC PF00931.22 EGG13756.1 - 0.00041 19.6 0.0 0.78 8.9 0.0 3.6 4 0 0 4 4 4 1 NB-ARC domain DUF815 PF05673.13 EGG13756.1 - 0.00054 19.2 0.0 0.16 11.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EGG13756.1 - 0.00076 20.0 0.0 0.16 12.5 0.0 2.7 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.6 EGG13756.1 - 0.0044 17.2 0.0 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 EGG13756.1 - 0.0047 16.9 0.7 0.64 9.9 0.0 3.3 2 2 2 4 4 4 1 NACHT domain TsaE PF02367.17 EGG13756.1 - 0.0057 16.6 0.0 3.1 7.8 0.0 2.7 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EGG13756.1 - 0.0065 16.2 0.0 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 EGG13756.1 - 0.0073 15.7 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.17 EGG13756.1 - 0.012 15.7 1.2 0.05 13.7 0.2 2.5 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_29 PF13555.6 EGG13756.1 - 0.014 15.1 0.0 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EGG13756.1 - 0.016 15.7 0.0 0.062 13.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGG13756.1 - 0.019 14.1 0.0 0.07 12.2 0.0 1.9 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 EGG13756.1 - 0.02 14.2 0.0 1 8.6 0.0 2.6 2 1 0 2 2 2 0 KaiC DUF2075 PF09848.9 EGG13756.1 - 0.02 14.1 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.11 EGG13756.1 - 0.023 14.8 0.1 4.2 7.5 0.0 3.2 4 0 0 4 4 3 0 Torsin Viral_helicase1 PF01443.18 EGG13756.1 - 0.042 13.6 0.0 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EGG13756.1 - 0.048 14.0 0.0 5.8 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGG13756.1 - 0.053 13.3 0.1 0.67 9.7 0.1 2.4 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGG13756.1 - 0.088 12.9 0.1 6.5 6.9 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_3 PF07726.11 EGG13756.1 - 0.1 12.5 0.1 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EGG13756.1 - 0.13 11.6 0.0 0.67 9.2 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin DEAD PF00270.29 EGG13756.1 - 0.15 11.8 0.3 5.2 6.8 0.0 3.3 4 1 0 5 5 5 0 DEAD/DEAH box helicase PhoH PF02562.16 EGG13756.1 - 0.15 11.5 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 EGG13757.1 - 1.1e-40 139.1 0.1 4.7e-40 137.1 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGG13757.1 - 1.2e-15 57.1 0.2 2.5e-15 56.1 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGG13757.1 - 5.5e-12 45.3 0.1 1.5e-11 43.9 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGG13757.1 - 2e-06 27.8 0.2 1.4e-05 25.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGG13757.1 - 6e-06 26.8 0.1 0.0077 16.6 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 EGG13757.1 - 8.3e-05 22.8 0.0 0.0004 20.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGG13757.1 - 0.00016 21.5 0.0 0.00047 19.9 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGG13757.1 - 0.00075 19.8 1.6 0.077 13.3 0.0 2.9 2 1 1 3 3 3 1 AAA domain PhoH PF02562.16 EGG13757.1 - 0.0022 17.5 0.0 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EGG13757.1 - 0.0034 16.8 0.1 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EGG13757.1 - 0.0034 16.6 0.0 0.0076 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EGG13757.1 - 0.0046 17.1 0.0 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGG13757.1 - 0.023 14.4 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 EGG13757.1 - 0.036 14.1 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGG13757.1 - 0.053 13.2 0.3 0.26 11.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGG13757.1 - 0.065 12.9 0.0 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 EGG13757.1 - 0.066 12.5 0.4 0.19 11.0 0.0 2.0 3 0 0 3 3 3 0 KaiC AAA_7 PF12775.7 EGG13757.1 - 0.07 12.6 0.1 0.17 11.4 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGG13757.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase E1-E2_ATPase PF00122.20 EGG13757.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 E1-E2 ATPase AAA_11 PF13086.6 EGG13757.1 - 0.12 12.1 0.8 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Tropomyosin_1 PF12718.7 EGG13757.1 - 0.47 10.6 6.8 0.17 12.0 3.9 1.7 2 0 0 2 2 2 0 Tropomyosin like Pkinase_Tyr PF07714.17 EGG13758.1 - 1.5e-54 185.1 0.0 2.4e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG13758.1 - 1.5e-45 155.6 0.0 2.7e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Roc PF08477.13 EGG13758.1 - 1.6e-21 76.7 0.2 6.7e-20 71.5 0.1 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG13758.1 - 1.4e-10 41.0 0.7 5.9e-10 39.0 0.1 2.1 2 0 0 2 2 2 1 Ras family Arf PF00025.21 EGG13758.1 - 1.9e-05 24.2 0.6 0.00015 21.3 0.0 2.6 3 0 0 3 3 3 1 ADP-ribosylation factor family COR PF16095.5 EGG13758.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain MMR_HSR1 PF01926.23 EGG13758.1 - 0.02 15.0 0.6 0.12 12.5 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase WD40 PF00400.32 EGG13758.1 - 0.032 15.1 0.4 24 6.0 0.2 3.6 2 0 0 2 2 2 0 WD domain, G-beta repeat LRR_8 PF13855.6 EGG13758.1 - 0.058 13.2 0.2 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Leucine rich repeat MORN PF02493.20 EGG13759.1 - 8.4e-14 50.5 18.9 0.00015 21.4 0.5 5.3 6 0 0 6 6 6 4 MORN repeat SET PF00856.28 EGG13759.1 - 1.2e-06 29.0 4.9 4.6e-05 23.9 0.2 3.2 2 1 0 2 2 2 1 SET domain Raptor_N PF14538.6 EGG13759.1 - 0.005 16.8 0.1 1.2 9.0 0.1 2.4 1 1 1 2 2 2 2 Raptor N-terminal CASPase like domain VPS11_C PF12451.8 EGG13759.1 - 0.7 10.2 4.2 1.7 8.9 4.2 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal WD40 PF00400.32 EGG13760.1 - 3.7e-16 59.2 9.9 1.4e-07 32.1 0.0 6.8 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG13760.1 - 0.01 16.1 0.0 0.066 13.5 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain FlaC_arch PF05377.11 EGG13761.1 - 5.6 7.4 33.5 0.29 11.6 0.9 6.7 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) PIP49_N PF14875.6 EGG13763.1 - 1.6 8.6 8.0 5 7.0 0.0 2.9 3 0 0 3 3 3 0 N-term cysteine-rich ER, FAM69 TRP PF06011.12 EGG13764.1 - 0.00024 19.9 3.1 0.0004 19.2 0.5 1.9 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel Colicin_V PF02674.16 EGG13764.1 - 0.001 19.0 1.7 0.01 15.8 0.7 2.2 2 0 0 2 2 2 1 Colicin V production protein OST3_OST6 PF04756.13 EGG13764.1 - 0.0055 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family SUR7 PF06687.12 EGG13764.1 - 0.012 15.2 0.5 0.012 15.2 0.5 2.3 1 1 1 2 2 2 0 SUR7/PalI family DUF3810 PF12725.7 EGG13764.1 - 0.087 12.2 0.3 0.17 11.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF2189 PF09955.9 EGG13764.1 - 0.1 12.9 0.2 0.1 12.9 0.2 1.7 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) Fungus-induced PF10917.8 EGG13764.1 - 0.17 12.2 4.5 2.1 8.7 0.2 2.9 3 0 0 3 3 3 0 Fungus-induced protein Vma12 PF11712.8 EGG13764.1 - 1.9 8.5 7.0 4.2 7.4 1.9 2.9 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SUIM_assoc PF16619.5 EGG13765.1 - 0.0015 18.6 4.3 0.0015 18.6 4.3 6.2 5 1 1 6 6 6 3 Unstructured region C-term to UIM in Ataxin3 Sulfotransfer_2 PF03567.14 EGG13768.1 - 9.5e-08 32.2 0.2 9.5e-08 32.2 0.2 1.9 2 0 0 2 2 2 1 Sulfotransferase family DUF2371 PF10177.9 EGG13768.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Sulfotransfer_1 PF00685.27 EGG13768.1 - 0.88 9.0 5.2 0.099 12.1 0.4 1.9 2 1 0 2 2 2 0 Sulfotransferase domain PRP21_like_P PF12230.8 EGG13769.1 - 4.9e-43 147.5 1.3 4.9e-43 147.5 1.3 2.9 3 0 0 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EGG13769.1 - 3e-32 110.4 2.6 2.7e-17 62.5 0.0 2.5 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 EGG13769.1 - 4.8e-08 32.6 0.1 1.4e-07 31.2 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGG13769.1 - 5.5e-05 23.6 0.1 0.00021 21.7 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin-like domain Pex14_N PF04695.13 EGG13769.1 - 0.52 11.0 21.5 3.2 8.4 6.0 2.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glycoprotein PF03409.15 EGG13769.1 - 0.87 8.4 8.8 0.076 11.8 2.9 1.9 2 0 0 2 2 2 0 Transmembrane glycoprotein Mito_fiss_reg PF05308.11 EGG13769.1 - 5.2 7.1 23.8 1.7 8.7 5.3 3.0 3 0 0 3 3 3 0 Mitochondrial fission regulator DUF218 PF02698.17 EGG13770.1 - 1.2e-19 70.6 0.1 3e-19 69.4 0.0 1.6 2 0 0 2 2 2 1 DUF218 domain ETRAMP PF09716.10 EGG13770.1 - 0.013 15.5 5.2 0.025 14.6 5.2 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Tmemb_9 PF05434.11 EGG13770.1 - 0.08 12.8 0.3 0.17 11.8 0.3 1.5 1 0 0 1 1 1 0 TMEM9 Phosphodiest PF01663.22 EGG13771.1 - 0.00023 20.9 0.8 0.0019 17.8 0.2 2.1 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase CBM49 PF09478.10 EGG13772.1 - 2.3e-12 47.0 0.2 3.3e-12 46.6 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 RMF PF04957.12 EGG13772.1 - 0.033 14.4 0.0 0.05 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosome modulation factor CBM49 PF09478.10 EGG13773.1 - 2.3e-12 47.0 0.2 3.3e-12 46.6 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 RMF PF04957.12 EGG13773.1 - 0.033 14.4 0.0 0.05 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosome modulation factor CBM49 PF09478.10 EGG13774.1 - 7.5e-11 42.2 0.2 1.1e-10 41.7 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM_2 PF00553.19 EGG13774.1 - 0.029 14.7 0.1 0.037 14.3 0.1 1.2 1 0 0 1 1 1 0 Cellulose binding domain MMR_HSR1 PF01926.23 EGG13775.1 - 1e-17 64.2 3.0 1.4e-17 63.8 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG13775.1 - 2.9e-07 30.1 0.0 5.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGG13775.1 - 3e-07 30.5 0.1 0.00013 21.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EGG13775.1 - 1.1e-06 28.8 3.4 0.00063 19.8 0.2 3.3 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EGG13775.1 - 0.00013 21.6 1.7 0.0044 16.6 0.2 3.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 EGG13775.1 - 0.00027 20.1 0.3 0.00064 18.9 0.0 1.8 1 1 1 2 2 2 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 EGG13775.1 - 0.003 16.9 0.0 0.006 15.9 0.0 1.6 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 EGG13775.1 - 0.016 15.7 0.2 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 EGG13775.1 - 0.016 15.4 0.0 0.064 13.5 0.0 2.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase F-box PF00646.33 EGG13776.1 - 0.013 15.3 0.8 0.032 14.1 0.8 1.7 1 0 0 1 1 1 0 F-box domain Amelogenin PF02948.15 EGG13776.1 - 3.4 8.3 17.9 0.36 11.5 11.4 2.5 2 0 0 2 2 2 0 Amelogenin GATA PF00320.27 EGG13779.1 - 2.2e-08 33.6 9.0 5.1e-08 32.4 9.0 1.7 1 0 0 1 1 1 1 GATA zinc finger zf-CCHH PF10283.9 EGG13779.1 - 0.044 13.8 0.7 0.08 12.9 0.7 1.4 1 0 0 1 1 1 0 PBZ domain SR-25 PF10500.9 EGG13781.1 - 3.2 7.3 10.6 4.8 6.7 10.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Syntaxin PF00804.25 EGG13782.1 - 1.1e-40 139.5 11.2 1.3e-38 132.7 7.3 2.3 1 1 1 2 2 2 2 Syntaxin SNARE PF05739.19 EGG13782.1 - 2.1e-12 46.8 0.8 5.1e-12 45.6 0.8 1.7 1 0 0 1 1 1 1 SNARE domain WXG100 PF06013.12 EGG13782.1 - 0.0081 16.4 1.6 28 5.0 0.0 4.2 4 0 0 4 4 4 0 Proteins of 100 residues with WXG Syntaxin_2 PF14523.6 EGG13782.1 - 0.015 15.7 9.2 0.015 15.7 9.2 3.1 2 2 0 2 2 2 0 Syntaxin-like protein PLC-beta_C PF08703.10 EGG13782.1 - 0.073 13.0 13.6 0.022 14.7 8.1 2.6 1 1 1 2 2 2 0 PLC-beta C terminal OppC_N PF12911.7 EGG13782.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Sulfatase_C PF14707.6 EGG13782.1 - 0.17 12.6 1.6 0.27 12.0 0.1 2.2 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF3568 PF12092.8 EGG13782.1 - 0.19 11.8 6.5 2.9 8.0 0.3 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF3568) DUF745 PF05335.13 EGG13782.1 - 0.64 9.7 6.8 5.9 6.6 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Sfi1_C PF10638.9 EGG13782.1 - 0.69 10.7 5.4 0.48 11.2 2.1 2.2 2 0 0 2 2 2 0 Spindle body associated protein C-terminus DUF4179 PF13786.6 EGG13782.1 - 0.72 10.4 6.7 12 6.5 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Ima1_N PF09779.9 EGG13782.1 - 1.3 9.9 4.4 4.9 8.0 4.4 1.9 1 0 0 1 1 1 0 Ima1 N-terminal domain CotJB PF12652.7 EGG13782.1 - 1.4 9.2 5.4 17 5.7 0.2 3.1 2 0 0 2 2 2 0 CotJB protein CorA PF01544.18 EGG13782.1 - 4.9 6.4 11.5 1.2 8.4 0.7 2.7 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein Sec8_exocyst PF04048.14 EGG13782.1 - 6.3 6.7 11.8 0.52 10.2 2.5 2.9 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain TFIIB PF00382.19 EGG13783.1 - 2.6e-41 139.5 0.2 2.2e-20 72.5 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGG13783.1 - 3.6e-14 52.0 4.6 6.5e-14 51.2 4.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 EGG13783.1 - 0.0015 18.6 0.6 2 8.5 0.0 2.3 1 1 1 2 2 2 2 Cyclin, C-terminal domain RB_B PF01857.20 EGG13783.1 - 0.016 15.2 0.1 0.12 12.4 0.0 2.3 2 1 0 2 2 2 0 Retinoblastoma-associated protein B domain HTH_Tnp_ISL3 PF13542.6 EGG13783.1 - 0.024 14.0 0.1 0.075 12.5 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 EGG13783.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Cyclin_C_2 PF16899.5 EGG13784.1 - 3.3e-14 53.1 1.1 5.2e-13 49.3 0.1 3.1 2 1 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 EGG13784.1 - 5.5e-11 42.3 0.9 1.4e-10 41.0 0.9 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.32 EGG13784.1 - 6.1e-10 39.5 6.8 0.00064 20.5 0.6 5.3 3 1 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG13784.1 - 1e-05 25.7 0.1 0.54 10.6 0.0 3.6 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIB PF00382.19 EGG13784.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Kinesin PF00225.23 EGG13785.1 - 1.8e-111 372.3 1.6 1.8e-111 372.3 1.6 2.8 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGG13785.1 - 5.9e-27 94.4 2.0 9.8e-27 93.7 0.2 2.4 2 0 0 2 2 2 1 Microtubule binding zf-UBR PF02207.20 EGG13786.1 - 6.8e-16 58.2 18.0 6.8e-16 58.2 18.0 2.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Acyl-CoA_dh_M PF02770.19 EGG13786.1 - 1e-15 57.7 0.0 1.9e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 EGG13786.1 - 5.3e-09 35.9 0.0 1.5e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 EGG13786.1 - 3.5e-07 30.5 0.0 6.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RNF111_N PF15303.6 EGG13786.1 - 0.0093 15.8 0.3 0.0093 15.8 0.3 1.6 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase Arkadia N-terminus Acyl-CoA_dh_2 PF08028.11 EGG13786.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain MgsA_C PF12002.8 EGG13786.1 - 0.15 12.0 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal DNase_II PF03265.15 EGG13787.1 - 3.7e-12 46.2 3.1 2.8e-07 30.1 0.1 2.5 2 0 0 2 2 2 2 Deoxyribonuclease II APC_u15 PF16636.5 EGG13787.1 - 8.6 6.9 11.7 0.25 11.8 4.7 2.2 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 eIF-6 PF01912.18 EGG13791.1 - 1.4e-66 223.7 0.5 2.4e-66 222.9 0.4 1.4 2 0 0 2 2 2 1 eIF-6 family Methyltransf_4 PF02390.17 EGG13792.1 - 6.2e-51 172.3 0.0 1e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EGG13792.1 - 1.1e-05 26.0 0.0 2.7e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGG13792.1 - 7.9e-05 22.3 0.0 0.00017 21.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGG13792.1 - 0.00016 21.5 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG13792.1 - 0.00029 21.4 0.0 0.03 15.0 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGG13792.1 - 0.00032 20.7 0.4 0.00067 19.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG13792.1 - 0.0023 18.6 0.0 0.0089 16.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 EGG13792.1 - 0.013 14.6 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase UQ_con PF00179.26 EGG13793.1 - 1.2e-38 131.9 0.0 1.3e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGG13793.1 - 0.043 13.7 0.6 0.08 12.8 0.0 1.7 2 0 0 2 2 2 0 UEV domain PPR_2 PF13041.6 EGG13794.1 - 0.00011 22.3 0.1 2.3 8.5 0.0 4.2 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.20 EGG13794.1 - 0.0025 18.0 0.3 0.79 10.1 0.0 3.8 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.6 EGG13794.1 - 0.0086 16.1 5.5 0.42 10.7 0.0 4.3 4 1 1 5 5 5 2 Pentatricopeptide repeat domain F_actin_bind PF08919.10 EGG13794.1 - 0.052 13.6 0.7 15 5.7 0.0 2.7 2 0 0 2 2 2 0 F-actin binding RFX_DNA_binding PF02257.15 EGG13794.1 - 0.57 10.9 7.0 0.74 10.5 0.1 3.6 3 0 0 3 3 3 0 RFX DNA-binding domain NAD_binding_2 PF03446.15 EGG13797.1 - 1.3e-52 178.2 1.4 1.8e-52 177.7 1.4 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGG13797.1 - 2.1e-33 115.2 0.0 6.1e-33 113.7 0.0 1.8 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 EGG13797.1 - 4e-09 36.1 0.1 4e-09 36.1 0.1 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGG13797.1 - 1.6e-07 31.8 0.2 4.8e-07 30.3 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EGG13797.1 - 6.7e-07 29.0 0.1 1.1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 EGG13797.1 - 2.4e-05 24.0 0.3 0.0035 16.9 0.1 2.3 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EGG13797.1 - 0.00012 22.0 0.2 0.00044 20.2 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EGG13797.1 - 0.0064 16.6 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.15 EGG13797.1 - 0.0066 15.4 0.1 0.0083 15.1 0.1 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Urocanase PF01175.18 EGG13797.1 - 0.0096 15.6 0.2 0.022 14.4 0.0 1.7 2 0 0 2 2 2 1 Urocanase Rossmann-like domain TrkA_N PF02254.18 EGG13797.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short_C2 PF13561.6 EGG13797.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ApbA PF02558.16 EGG13797.1 - 0.036 13.7 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EGG13797.1 - 0.058 13.8 0.5 0.1 13.0 0.1 1.6 2 0 0 2 2 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 EGG13797.1 - 0.095 13.5 0.0 0.28 12.0 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Sec7 PF01369.20 EGG13798.1 - 3.7e-39 134.3 1.4 1.9e-30 105.9 0.3 2.3 1 1 1 2 2 2 2 Sec7 domain PH PF00169.29 EGG13798.1 - 1.3e-14 54.5 0.6 1.3e-14 54.5 0.6 1.9 2 0 0 2 2 2 1 PH domain HBS1_N PF08938.10 EGG13798.1 - 0.058 13.7 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 HBS1 N-terminus Holin_BhlA PF10960.8 EGG13798.1 - 0.13 12.2 1.0 0.67 10.0 0.5 2.3 2 0 0 2 2 2 0 BhlA holin family MIT PF04212.18 EGG13799.1 - 1.1e-43 147.1 18.1 6.6e-18 64.5 0.3 3.5 4 0 0 4 4 4 3 MIT (microtubule interacting and transport) domain DUF5388 PF17363.2 EGG13799.1 - 0.022 14.9 0.1 0.098 12.9 0.1 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5388) TPR_2 PF07719.17 EGG13799.1 - 0.029 14.5 4.8 14 6.1 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Use1 PF09753.9 EGG13799.1 - 0.1 12.3 6.6 0.032 14.0 3.2 1.9 2 0 0 2 2 2 0 Membrane fusion protein Use1 FliS PF02561.14 EGG13799.1 - 0.14 12.5 3.5 9.2 6.6 0.1 3.2 3 0 0 3 3 3 0 Flagellar protein FliS TPR_1 PF00515.28 EGG13799.1 - 0.31 10.9 6.6 4.8 7.2 0.1 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF357 PF04010.13 EGG13799.1 - 0.74 9.9 2.3 1.6 8.9 0.1 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF357) ENTH PF01417.20 EGG13800.1 - 1.6e-25 89.6 0.2 2.5e-25 89.0 0.2 1.3 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 EGG13800.1 - 0.14 12.0 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 VHS domain ENTH PF01417.20 EGG13801.1 - 2e-09 37.5 0.0 2.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 ENTH domain Rap_GAP PF02145.15 EGG13802.1 - 1.1e-51 175.0 3.2 1.1e-50 171.8 1.4 2.9 2 1 0 2 2 2 1 Rap/ran-GAP CNH PF00780.22 EGG13802.1 - 5.7e-36 124.5 0.6 1.2e-35 123.4 0.2 1.7 2 0 0 2 2 2 1 CNH domain RNA_pol_Rpb5_C PF01191.19 EGG13802.1 - 9.4e-31 105.5 0.3 2.4e-30 104.2 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EGG13802.1 - 2.2e-24 85.9 0.4 7.5e-24 84.1 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Sof1 PF04158.14 EGG13802.1 - 0.12 12.6 0.2 0.28 11.5 0.2 1.5 1 0 0 1 1 1 0 Sof1-like domain ABC2_membrane_3 PF12698.7 EGG13803.1 - 0.31 10.1 3.8 0.43 9.6 3.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-B_box PF00643.24 EGG13803.1 - 2.3 8.4 8.5 1.8 8.8 5.6 2.0 2 0 0 2 2 2 0 B-box zinc finger zf-C2H2_2 PF12756.7 EGG13804.1 - 2.5e-35 120.8 18.5 5.6e-28 97.2 7.1 3.6 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGG13804.1 - 9.4e-08 32.2 10.1 5.4e-06 26.5 5.5 4.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG13804.1 - 1.3e-07 31.7 1.5 1.3e-07 31.7 1.5 2.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGG13804.1 - 0.0033 18.1 21.2 0.006 17.3 0.5 4.8 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EGG13804.1 - 0.037 14.7 0.9 0.037 14.7 0.9 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 EGG13804.1 - 0.49 10.4 5.8 5.9 6.9 0.6 2.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 EGG13804.1 - 0.6 10.7 22.0 0.11 13.0 1.4 3.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-BED PF02892.15 EGG13804.1 - 3.6 7.7 11.6 0.54 10.3 0.1 3.7 3 0 0 3 3 3 0 BED zinc finger zf-H2C2_2 PF13465.6 EGG13804.1 - 8.1 7.1 16.1 0.27 11.7 1.5 4.4 4 0 0 4 4 4 0 Zinc-finger double domain BolA PF01722.18 EGG13805.1 - 3.5e-07 30.4 0.0 1.2e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 BolA-like protein DUF3447 PF11929.8 EGG13805.1 - 9.4e-06 25.5 11.6 0.00091 19.1 1.3 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EGG13805.1 - 0.0021 18.6 0.5 0.085 13.5 0.1 3.1 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) FidL_like PF15941.5 EGG13805.1 - 3.4 8.2 7.8 0.42 11.1 0.1 3.2 3 0 0 3 3 3 0 FidL-like putative membrane protein YhhN PF07947.14 EGG13807.1 - 5.2e-36 124.0 24.0 2e-34 118.8 24.0 2.2 1 1 0 1 1 1 1 YhhN family Virul_fac_BrkB PF03631.15 EGG13807.1 - 3.5 7.2 27.1 0.18 11.4 16.1 2.3 1 1 1 2 2 2 0 Virulence factor BrkB PX PF00787.24 EGG13808.1 - 1.3e-13 50.9 3.3 8.8e-13 48.2 0.3 3.1 2 0 0 2 2 2 1 PX domain Dynamin_N PF00350.23 EGG13808.1 - 0.00024 21.2 0.2 0.00024 21.2 0.2 4.7 3 2 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EGG13808.1 - 0.012 15.7 0.2 0.012 15.7 0.2 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase Kelch_3 PF13415.6 EGG13809.1 - 9e-46 153.4 12.2 3.9e-11 42.9 0.2 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 EGG13809.1 - 3.2e-43 145.5 9.4 8.9e-10 38.4 0.1 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain RasGEF PF00617.19 EGG13809.1 - 3.1e-39 135.0 0.4 8e-39 133.6 0.4 1.8 1 0 0 1 1 1 1 RasGEF domain Kelch_1 PF01344.25 EGG13809.1 - 7.2e-38 127.9 0.3 6e-10 38.6 0.1 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 EGG13809.1 - 7.1e-36 121.3 11.2 2.4e-08 33.9 0.1 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EGG13809.1 - 5e-27 93.4 4.5 1.5e-05 24.9 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGG13809.1 - 8.7e-23 79.4 4.6 2.5e-05 24.0 0.1 6.7 6 0 0 6 6 6 5 Kelch motif RasGEF_N PF00618.20 EGG13809.1 - 0.00032 20.9 0.0 0.0018 18.5 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif DUF2013 PF09431.10 EGG13810.1 - 2.9e-16 59.9 0.1 3.1e-15 56.6 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) DUF2373 PF10180.9 EGG13811.1 - 6.7e-20 70.7 0.4 1.6e-19 69.5 0.4 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) zf-4CXXC_R1 PF10497.9 EGG13812.1 - 1.4e-06 28.4 13.7 3.5e-06 27.1 13.7 1.7 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 PWWP PF00855.17 EGG13812.1 - 0.00046 20.5 0.0 0.00046 20.5 0.0 3.8 4 1 0 4 4 4 1 PWWP domain AT_hook PF02178.19 EGG13812.1 - 1.5 9.0 6.3 4.4 7.5 0.1 2.5 2 0 0 2 2 2 0 AT hook motif HEAT PF02985.22 EGG13814.1 - 5.3e-08 32.5 2.5 0.0013 18.8 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EGG13814.1 - 7.9e-08 32.6 0.2 0.01 16.2 0.0 3.9 4 0 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 EGG13814.1 - 0.013 16.0 0.9 0.25 11.9 0.0 3.1 3 0 0 3 3 3 0 HEAT-like repeat Cnd1 PF12717.7 EGG13814.1 - 0.041 13.9 2.9 4.3 7.4 0.4 3.7 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 UPF0561 PF10573.9 EGG13815.1 - 0.018 15.1 0.5 0.018 15.1 0.5 2.5 2 1 0 2 2 2 0 Uncharacterised protein family UPF0561 Lentivirus_VIF PF05851.11 EGG13815.1 - 0.37 9.7 2.2 0.73 8.7 1.1 1.9 2 0 0 2 2 2 0 Lentivirus virion infectivity factor (VIF) GvpL_GvpF PF06386.11 EGG13815.1 - 0.49 10.3 0.0 0.49 10.3 0.0 3.1 2 1 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF ING PF12998.7 EGG13815.1 - 1.5 9.5 32.9 0.23 12.0 5.9 4.2 3 1 1 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding SpecificRecomb PF10136.9 EGG13815.1 - 6.9 4.8 10.0 13 4.0 10.0 1.5 1 0 0 1 1 1 0 Site-specific recombinase Kelch_1 PF01344.25 EGG13817.1 - 4.1e-47 157.5 1.3 9.6e-08 31.5 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGG13817.1 - 2.9e-43 145.6 2.7 1.5e-07 31.3 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EGG13817.1 - 4.3e-41 137.9 5.9 1.4e-05 25.2 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGG13817.1 - 5.6e-40 134.9 1.9 2e-11 43.9 0.0 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG13817.1 - 2.4e-38 129.5 0.3 2.4e-06 27.4 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EGG13817.1 - 9.3e-36 120.5 6.8 7.3e-07 28.9 0.0 6.3 6 0 0 6 6 6 6 Kelch motif FRG1 PF06229.12 EGG13817.1 - 0.044 13.5 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 FRG1-like domain F-box-like PF12937.7 EGG13817.1 - 0.091 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 F-box-like LCAT PF02450.15 EGG13818.1 - 6.1e-64 216.6 0.7 5.8e-54 183.8 0.0 2.3 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 EGG13818.1 - 3.9e-05 23.5 0.0 0.00041 20.1 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 EGG13818.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EGG13818.1 - 0.0026 17.3 0.0 0.0063 16.0 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 EGG13818.1 - 0.0038 16.9 0.0 0.013 15.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.12 EGG13818.1 - 0.0074 15.8 0.0 0.019 14.5 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 EGG13818.1 - 0.058 12.7 0.0 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 EGG13818.1 - 0.083 13.5 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EGG13818.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 EGG13818.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ser_hydrolase PF06821.13 EGG13818.1 - 0.13 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase CBM77 PF18283.1 EGG13819.1 - 0.061 13.7 0.3 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 Carbohydrate binding module 77 MnmE_helical PF12631.7 EGG13820.1 - 1.2e-47 162.8 1.8 2.1e-47 162.0 1.8 1.4 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EGG13820.1 - 2.3e-35 121.4 0.2 1.8e-34 118.5 0.0 2.5 3 0 0 3 3 3 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EGG13820.1 - 5e-20 71.7 0.1 1.7e-19 70.0 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG13820.1 - 5.7e-08 32.4 0.6 1.4e-07 31.2 0.6 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGG13820.1 - 7.7e-06 26.1 3.6 2.4e-05 24.5 1.0 3.1 2 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EGG13820.1 - 2.7e-05 24.1 0.8 0.081 12.8 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGG13820.1 - 0.00011 21.8 0.2 0.011 15.3 0.2 2.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 EGG13820.1 - 0.029 14.6 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 EGG13820.1 - 0.046 13.4 4.4 0.53 10.0 0.0 3.2 3 1 0 3 3 3 0 Guanylate kinase AAA_22 PF13401.6 EGG13820.1 - 0.053 13.8 0.2 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGG13820.1 - 0.058 13.8 3.1 0.78 10.2 0.6 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGG13820.1 - 0.1 13.2 1.9 0.24 11.9 0.1 2.7 3 1 0 3 3 2 0 AAA domain ABC_tran PF00005.27 EGG13820.1 - 0.44 11.1 9.5 3.1 8.3 9.6 2.4 1 1 0 1 1 1 0 ABC transporter FmiP_Thoc5 PF09766.9 EGG13821.1 - 0.03 13.6 0.8 1.2 8.4 0.3 2.1 1 1 1 2 2 2 0 Fms-interacting protein/Thoc5 TssO PF17561.2 EGG13822.1 - 0.0069 16.5 1.0 0.016 15.3 1.0 1.5 1 0 0 1 1 1 1 Type VI secretion system, TssO MAAL_C PF07476.11 EGG13822.1 - 0.13 11.4 0.5 0.51 9.5 0.1 1.9 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus MACPF PF01823.19 EGG13823.1 - 2.4e-21 76.8 6.1 5.2e-21 75.7 6.1 1.5 1 0 0 1 1 1 1 MAC/Perforin domain Integrin_b_cyt PF08725.11 EGG13823.1 - 0.049 13.3 1.2 0.15 11.8 1.2 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain MACPF PF01823.19 EGG13824.1 - 2.5e-21 76.7 6.7 3.4e-21 76.3 5.2 2.1 2 0 0 2 2 2 1 MAC/Perforin domain F-box-like PF12937.7 EGG13825.1 - 0.038 13.9 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 F-box-like Fcf1 PF04900.12 EGG13825.1 - 0.75 10.2 3.5 0.63 10.5 0.3 2.6 2 1 1 3 3 3 0 Fcf1 HSP70 PF00012.20 EGG13827.1 - 5.3e-262 870.4 11.8 6e-262 870.2 11.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGG13827.1 - 4.5e-14 52.0 0.4 6e-13 48.3 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGG13827.1 - 0.0026 17.5 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EGG13827.1 - 0.0032 16.8 0.1 0.0087 15.4 0.1 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EGG13827.1 - 0.008 15.7 0.1 4.5 6.7 0.0 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 EGG13827.1 - 0.0086 15.1 0.3 0.22 10.5 0.1 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Pex19 PF04614.12 EGG13827.1 - 0.065 13.0 8.7 0.021 14.6 5.6 1.6 2 0 0 2 2 2 0 Pex19 protein family AAA_18 PF13238.6 EGG13828.1 - 4e-17 63.0 0.5 1.9e-16 60.8 0.4 2.0 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EGG13828.1 - 5.7e-07 29.6 0.5 1.9e-06 27.9 0.4 1.9 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_28 PF13521.6 EGG13828.1 - 2e-06 28.2 0.1 0.00042 20.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGG13828.1 - 0.00017 21.7 0.1 0.00043 20.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain Apc15p PF05841.11 EGG13828.1 - 0.014 16.2 1.2 0.014 16.2 1.2 1.4 2 0 0 2 2 2 0 Apc15p protein CoaE PF01121.20 EGG13828.1 - 0.022 14.4 0.1 0.059 13.0 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase Tim54 PF11711.8 EGG13828.1 - 0.035 12.9 0.2 0.041 12.7 0.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EVI2A PF05399.11 EGG13828.1 - 0.11 12.1 4.2 0.16 11.5 4.2 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) AAA_22 PF13401.6 EGG13828.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain MFS_1_like PF12832.7 EGG13829.1 - 5.9e-94 315.1 23.7 1.1e-93 314.2 23.7 1.4 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EGG13829.1 - 1e-17 64.1 68.2 2.6e-10 39.8 21.3 4.0 2 2 2 4 4 4 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 EGG13829.1 - 2.4e-09 36.7 33.6 1.5e-05 24.2 11.0 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 EGG13829.1 - 5.5e-09 35.3 36.4 2.4e-06 26.6 19.4 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_2 PF13347.6 EGG13829.1 - 0.021 13.4 41.6 0.017 13.7 10.8 3.6 2 1 1 3 3 3 0 MFS/sugar transport protein SR-25 PF10500.9 EGG13829.1 - 0.085 12.5 1.9 0.14 11.7 1.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 EGG13830.1 - 7.3e-38 130.4 0.0 2.3e-37 128.8 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13830.1 - 3.7e-20 72.3 0.0 1.9e-19 70.0 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 EGG13830.1 - 5.7e-16 58.9 0.3 5.7e-16 58.9 0.3 1.9 2 0 0 2 2 2 1 Ribonuclease 2-5A RIO1 PF01163.22 EGG13830.1 - 0.0068 16.0 0.1 0.031 13.9 0.1 2.1 1 0 0 1 1 1 1 RIO1 family Ribosomal_60s PF00428.19 EGG13830.1 - 0.008 16.7 2.6 2.5 8.7 0.5 2.7 2 0 0 2 2 2 2 60s Acidic ribosomal protein Kdo PF06293.14 EGG13830.1 - 0.009 15.4 0.1 0.024 14.0 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf_C2HC_14 PF18574.1 EGG13830.1 - 0.05 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 C2HC Zing finger domain APH PF01636.23 EGG13830.1 - 0.22 11.4 0.1 0.42 10.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.6 EGG13831.1 - 3.2e-13 49.3 8.7 8.7e-13 47.9 8.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG13831.1 - 5.2e-05 23.0 8.5 0.00016 21.4 8.5 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGG13831.1 - 0.0052 17.1 9.4 0.027 14.8 9.4 2.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGG13831.1 - 0.0058 16.6 8.1 0.02 14.9 8.1 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-P11 PF03854.14 EGG13831.1 - 0.9 9.3 6.6 2.7 7.7 6.6 1.9 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_UBOX PF13445.6 EGG13831.1 - 4.7 7.3 8.4 5.2 7.2 1.9 3.3 3 0 0 3 3 3 0 RING-type zinc-finger Pkinase PF00069.25 EGG13832.1 - 1.7e-67 227.6 0.0 3.2e-67 226.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13832.1 - 2e-31 109.2 0.0 4.4e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG13832.1 - 4.6e-10 39.3 0.0 1.3e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGG13832.1 - 0.00063 19.4 0.4 0.00063 19.4 0.4 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 EGG13832.1 - 0.0018 17.7 0.0 0.004 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EGG13832.1 - 0.015 14.8 0.1 0.015 14.8 0.1 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Cofilin_ADF PF00241.20 EGG13833.1 - 1.8e-26 92.3 1.2 2.1e-26 92.1 1.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein EF_TS PF00889.19 EGG13833.1 - 0.051 13.2 0.0 0.061 12.9 0.0 1.1 1 0 0 1 1 1 0 Elongation factor TS N6-adenineMlase PF10237.9 EGG13834.1 - 3.8e-45 153.6 0.7 5e-45 153.2 0.7 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 EGG13834.1 - 0.028 14.0 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF943 PF06092.12 EGG13834.1 - 0.063 12.9 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) DUF4201 PF13870.6 EGG13834.1 - 0.33 10.7 3.4 0.21 11.3 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) RasGEF PF00617.19 EGG13835.1 - 7.1e-53 179.4 0.2 1.6e-52 178.3 0.2 1.6 1 0 0 1 1 1 1 RasGEF domain RCC1 PF00415.18 EGG13835.1 - 5.7e-36 122.9 3.7 3.3e-11 43.6 0.0 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG13835.1 - 4.4e-23 80.5 1.2 7.7e-10 38.3 0.5 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RhoGEF PF00621.20 EGG13835.1 - 2.6e-19 70.2 0.3 2.6e-19 70.2 0.3 3.1 4 0 0 4 4 4 1 RhoGEF domain RasGEF_N PF00618.20 EGG13835.1 - 1.3e-17 63.9 4.8 5.4e-17 62.0 1.5 3.2 2 1 0 2 2 2 1 RasGEF N-terminal motif PAP2 PF01569.21 EGG13836.1 - 5.6e-06 26.2 0.0 2e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 PAP2 superfamily DUF3437 PF11919.8 EGG13836.1 - 0.15 12.0 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Dyp_perox PF04261.12 EGG13837.1 - 5.3e-65 219.5 0.0 6.8e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family Dyp_perox PF04261.12 EGG13838.1 - 1.8e-70 237.5 0.0 2.6e-70 237.0 0.0 1.3 1 1 0 1 1 1 1 Dyp-type peroxidase family Tma16 PF11176.8 EGG13839.1 - 1.5e-34 119.0 8.5 3.6e-34 117.8 8.5 1.7 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Ribosomal_L28e PF01778.17 EGG13839.1 - 1.4e-22 80.6 3.3 1.4e-22 80.6 3.3 2.5 3 0 0 3 3 3 1 Ribosomal L28e protein family Flg_bbr_C PF06429.13 EGG13839.1 - 0.12 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal U-box PF04564.15 EGG13840.1 - 2.3e-20 72.5 1.7 5.2e-20 71.4 0.7 2.2 2 0 0 2 2 2 1 U-box domain DUF2973 PF11189.8 EGG13840.1 - 7.6 6.7 6.7 7.6 6.7 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2973) NUDIX PF00293.28 EGG13841.1 - 3.8e-20 72.3 0.1 5.2e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4904 PF16247.5 EGG13841.1 - 0.12 12.1 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) RhoGAP PF00620.27 EGG13842.1 - 5.3e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain BUD22 PF09073.10 EGG13842.1 - 0.00023 20.6 18.4 0.00024 20.6 18.4 1.2 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 EGG13842.1 - 0.0006 19.3 26.4 0.00064 19.3 26.4 1.1 1 0 0 1 1 1 1 SDA1 Presenilin PF01080.17 EGG13842.1 - 0.0087 14.9 5.8 0.01 14.6 5.8 1.1 1 0 0 1 1 1 1 Presenilin Zip PF02535.22 EGG13842.1 - 0.028 13.7 1.7 0.03 13.6 1.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Mpp10 PF04006.12 EGG13842.1 - 1.3 7.4 31.5 1.8 6.9 31.5 1.2 1 0 0 1 1 1 0 Mpp10 protein NPR3 PF03666.13 EGG13842.1 - 2.2 7.0 11.9 3 6.5 11.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PNISR PF15996.5 EGG13842.1 - 3.6 7.8 21.3 6.4 7.0 21.3 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Nop14 PF04147.12 EGG13842.1 - 5.3 5.1 34.8 6.7 4.8 34.8 1.1 1 0 0 1 1 1 0 Nop14-like family Cnd2 PF05786.14 EGG13842.1 - 8.1 5.0 20.8 11 4.5 20.8 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 YL1 PF05764.13 EGG13843.1 - 3.6e-24 86.2 29.5 3.6e-24 86.2 29.5 1.9 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 EGG13843.1 - 4.3e-09 36.0 0.5 8.1e-09 35.1 0.1 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Spt5_N PF11942.8 EGG13843.1 - 0.79 10.7 25.4 0.67 11.0 2.7 2.9 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal PI3K_1B_p101 PF10486.9 EGG13843.1 - 1.6 6.4 22.4 0.039 11.8 15.3 1.7 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit UDPGP PF01704.18 EGG13844.1 - 7.3e-48 163.2 0.1 1e-47 162.7 0.1 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EGG13844.1 - 0.0036 17.7 0.0 0.0061 16.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain F-actin_cap_A PF01267.17 EGG13845.1 - 2e-89 299.6 1.1 2.3e-89 299.4 1.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit F_actin_cap_B PF01115.17 EGG13845.1 - 0.056 13.1 0.5 0.091 12.4 0.5 1.4 1 0 0 1 1 1 0 F-actin capping protein, beta subunit TRAPP PF04051.16 EGG13846.1 - 1.7e-40 138.1 0.1 2e-40 137.9 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component FoP_duplication PF13865.6 EGG13847.1 - 2e-05 25.0 27.2 2e-05 25.0 27.2 3.1 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 SNF2_N PF00176.23 EGG13848.1 - 1.5e-72 244.2 0.0 1.5e-72 244.2 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 EGG13848.1 - 2.1e-40 137.3 3.9 2.1e-40 137.3 3.9 3.7 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 EGG13848.1 - 1.5e-20 74.0 11.8 1.5e-20 74.0 11.8 5.9 5 0 0 5 5 5 1 HAND Helicase_C PF00271.31 EGG13848.1 - 6e-19 68.4 0.1 4e-18 65.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.31 EGG13848.1 - 2.2e-07 30.9 1.3 0.0067 16.6 0.1 3.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 EGG13848.1 - 7.6e-07 28.6 0.0 7.6e-07 28.6 0.0 3.2 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DBINO PF13892.6 EGG13848.1 - 3.6e-06 27.4 9.1 3.6e-06 27.4 9.1 4.9 4 0 0 4 4 4 1 DNA-binding domain DEAD PF00270.29 EGG13848.1 - 3.9e-06 26.7 0.0 1.8e-05 24.6 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec8_exocyst PF04048.14 EGG13848.1 - 0.035 14.0 0.1 0.035 14.0 0.1 2.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain AAA_14 PF13173.6 EGG13848.1 - 0.21 11.7 4.4 0.59 10.2 0.1 2.9 2 0 0 2 2 2 0 AAA domain Ribosomal_L34 PF00468.17 EGG13850.1 - 2.9e-19 68.8 8.4 4.1e-19 68.3 8.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Peptidase_M32 PF02074.15 EGG13850.1 - 0.01 14.6 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Phosducin PF02114.16 EGG13851.1 - 0.0066 15.4 0.1 0.0068 15.4 0.1 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EGG13851.1 - 0.014 15.4 0.5 0.015 15.2 0.5 1.1 1 0 0 1 1 1 0 Thioredoxin DUF35_N PF12172.8 EGG13851.1 - 0.023 14.6 0.6 0.041 13.8 0.6 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF3039 PF11238.8 EGG13851.1 - 0.18 11.6 1.3 0.24 11.2 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3039) Pkinase_Tyr PF07714.17 EGG13852.1 - 2.7e-62 210.4 0.0 4.6e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG13852.1 - 2.1e-47 161.7 0.0 7.3e-47 159.9 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain PIG-F PF06699.11 EGG13852.1 - 1.5e-29 103.4 11.1 3e-29 102.5 11.1 1.5 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Kinase-like PF14531.6 EGG13852.1 - 3.7e-05 23.2 0.0 8.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Caldesmon PF02029.15 EGG13852.1 - 1.3 7.8 35.0 0.015 14.1 26.3 2.1 2 0 0 2 2 2 0 Caldesmon Trypan_PARP PF05887.11 EGG13852.1 - 9.7 6.2 11.0 26 4.8 11.0 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ank_3 PF13606.6 EGG13854.1 - 0.014 15.8 0.3 40 5.3 0.0 5.5 6 0 0 6 6 6 0 Ankyrin repeat DUF508 PF04370.12 EGG13854.1 - 0.32 10.7 3.3 0.22 11.3 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF508) SR-25 PF10500.9 EGG13854.1 - 0.38 10.3 3.7 0.63 9.6 3.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hus1 PF04005.12 EGG13855.1 - 9.6e-44 149.6 5.6 7.2e-43 146.8 5.6 2.0 1 1 0 1 1 1 1 Hus1-like protein Linker_histone PF00538.19 EGG13855.1 - 5.2e-19 68.4 0.0 1.5e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 linker histone H1 and H5 family GHMP_kinases_N PF00288.26 EGG13856.1 - 2.1e-16 59.9 0.0 6.9e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGG13856.1 - 9.8e-06 25.9 0.0 2.6e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal CsgE PF10627.9 EGG13856.1 - 0.036 14.3 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 Curli assembly protein CsgE DUF2536 PF10750.9 EGG13856.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2536) FAD_binding_6 PF00970.24 EGG13857.1 - 1.8e-33 114.8 0.0 3.8e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGG13857.1 - 3.9e-29 101.5 0.0 7.8e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGG13857.1 - 7e-05 23.0 0.2 0.0038 17.4 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain RRM_1 PF00076.22 EGG13858.1 - 1.1e-69 230.2 0.6 1.1e-16 60.4 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG13858.1 - 6.8e-09 35.5 0.2 0.025 14.4 0.0 4.8 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EGG13858.1 - 8.6e-07 28.6 0.2 0.31 10.6 0.0 4.3 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG13858.1 - 0.00068 19.6 0.1 1.7 8.7 0.0 3.8 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EGG13858.1 - 0.0054 16.8 0.0 1.7 8.8 0.0 4.0 5 0 0 5 5 5 1 RNA recognition motif G-patch_2 PF12656.7 EGG13859.1 - 4e-23 81.3 0.3 2e-22 79.0 0.3 2.3 1 0 0 1 1 1 1 G-patch domain KOW PF00467.29 EGG13859.1 - 1.5e-12 47.0 3.4 0.00012 21.9 0.0 3.8 3 0 0 3 3 3 3 KOW motif KN17_SH3 PF18131.1 EGG13859.1 - 5.4e-11 42.4 1.7 8.9e-11 41.7 0.5 2.0 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain G-patch PF01585.23 EGG13859.1 - 1.2e-09 37.9 3.2 2.3e-09 37.0 3.2 1.5 1 0 0 1 1 1 1 G-patch domain DUF4698 PF15769.5 EGG13859.1 - 0.23 10.5 25.4 0.23 10.5 12.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) Cytadhesin_P30 PF07271.11 EGG13859.1 - 1.6 8.2 4.3 0.35 10.4 0.8 1.8 2 0 0 2 2 2 0 Cytadhesin P30/P32 Tir_receptor_N PF07490.11 EGG13859.1 - 7 6.4 17.0 2.5 7.8 4.8 2.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus WD40 PF00400.32 EGG13860.1 - 4.4e-19 68.5 6.0 0.0022 18.8 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG13860.1 - 8.2e-07 29.2 0.0 0.78 10.1 0.0 4.3 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGG13860.1 - 2.2e-05 24.8 3.5 9.9 6.8 0.1 5.2 5 0 0 5 5 5 1 PQQ-like domain Marek_SORF3 PF07153.11 EGG13860.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Marek's disease-like virus SORF3 protein BBS2_Mid PF14783.6 EGG13860.1 - 0.0015 18.6 0.1 1.9 8.6 0.0 3.8 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 EGG13860.1 - 0.0026 17.4 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain PHTB1_N PF14727.6 EGG13860.1 - 0.0046 16.4 0.6 0.089 12.1 0.1 2.1 2 0 0 2 2 2 1 PTHB1 N-terminus Frtz PF11768.8 EGG13860.1 - 0.038 12.3 0.0 0.45 8.8 0.0 2.2 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 EGG13860.1 - 0.37 10.8 3.8 1.3 9.1 0.2 3.4 4 0 0 4 4 4 0 PQQ enzyme repeat Costars PF14705.6 EGG13863.1 - 1.4e-27 95.7 0.6 1.5e-27 95.6 0.6 1.0 1 0 0 1 1 1 1 Costars CBM49 PF09478.10 EGG13864.1 - 1.3e-10 41.4 0.3 3.3e-10 40.1 0.3 1.6 1 1 0 1 1 1 1 Carbohydrate binding domain CBM49 Glyco_transf_10 PF00852.19 EGG13865.1 - 7e-33 113.8 0.0 1.6e-32 112.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Laminin_G_3 PF13385.6 EGG13865.1 - 1.2e-10 41.8 0.0 2.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Glyco_tran_10_N PF17039.5 EGG13865.1 - 0.00047 20.6 0.1 0.0023 18.4 0.0 2.2 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_trans_1_2 PF13524.6 EGG13865.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Methyltransf_3 PF01596.17 EGG13866.1 - 6.4e-64 215.0 0.5 1.3e-63 214.0 0.5 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGG13866.1 - 6.9e-12 46.3 0.1 1.9e-11 44.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG13866.1 - 0.051 14.3 0.0 0.15 12.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PQQ PF01011.21 EGG13866.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat DUF5096 PF17019.5 EGG13866.1 - 0.28 11.0 5.1 2 8.2 5.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5096) Membralin PF09746.9 EGG13866.1 - 2 7.4 7.7 2.6 7.0 7.7 1.4 1 0 0 1 1 1 0 Tumour-associated protein Lin-8 PF03353.15 EGG13866.1 - 4.3 6.8 15.1 5.9 6.3 15.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RNA_pol_L_2 PF13656.6 EGG13867.1 - 1.6e-27 95.1 0.1 1.9e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGG13867.1 - 8.9e-13 47.5 0.0 1.2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF3128 PF11326.8 EGG13868.1 - 1.1e-15 57.8 1.3 1.2e-15 57.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) DUF3439 PF11921.8 EGG13868.1 - 5.9 6.9 9.6 4.5 7.3 8.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) Actin PF00022.19 EGG13870.1 - 5.3e-150 499.5 0.0 1.7e-149 497.9 0.0 1.6 1 1 0 1 1 1 1 Actin CLU PF13236.6 EGG13871.1 - 1e-58 198.8 0.0 1.7e-58 198.0 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGG13871.1 - 1e-08 35.5 0.0 1e-08 35.5 0.0 2.3 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 ABC_tran PF00005.27 EGG13872.1 - 7e-24 84.9 0.0 1.3e-23 84.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGG13872.1 - 4.3e-14 52.4 37.2 1.1e-13 51.0 37.2 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGG13872.1 - 4.8e-10 39.7 0.4 6.9e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG13872.1 - 5.3e-05 22.8 0.5 0.0041 16.6 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 EGG13872.1 - 5.7e-05 23.8 0.0 0.00015 22.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) ABC2_membrane_2 PF12679.7 EGG13872.1 - 0.007 15.7 8.4 0.016 14.5 8.4 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 EGG13872.1 - 0.068 12.9 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EGG13872.1 - 0.2 11.4 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC2_membrane_5 PF13346.6 EGG13872.1 - 1.4 8.4 22.5 0.23 11.0 17.8 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 EGG13873.1 - 5.9e-34 117.7 35.1 1e-33 116.9 35.1 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 EGG13873.1 - 5.8e-27 94.9 0.0 1e-26 94.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGG13873.1 - 6e-07 29.6 0.1 0.00036 20.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGG13873.1 - 3.1e-05 23.9 1.2 0.066 12.9 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 EGG13873.1 - 0.0014 18.1 0.6 0.56 9.6 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGG13873.1 - 0.0062 16.3 0.5 0.017 14.8 0.5 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG13873.1 - 0.045 13.7 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_13 PF13166.6 EGG13873.1 - 0.12 11.1 1.6 0.31 9.7 0.3 1.9 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.22 EGG13874.1 - 6.6e-12 45.1 0.1 1.2e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG13874.1 - 2.9e-05 23.7 0.0 4.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 EGG13874.1 - 5.3e-05 23.0 1.0 5.3e-05 23.0 1.0 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGG13874.1 - 0.00034 20.6 4.1 0.00089 19.2 4.1 1.8 1 0 0 1 1 1 1 Zinc finger domain RRM_occluded PF16842.5 EGG13874.1 - 0.00042 20.1 0.0 0.00086 19.1 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif Torus PF16131.5 EGG13874.1 - 0.0011 19.6 1.8 0.0013 19.4 0.0 2.0 2 0 0 2 2 2 1 Torus domain RRM_3 PF08777.11 EGG13874.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif RNA_bind PF08675.11 EGG13874.1 - 0.0096 15.9 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 RNA binding domain DUF4799 PF16056.5 EGG13874.1 - 0.035 13.3 2.6 0.045 12.9 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4799) zf-CCCH_4 PF18044.1 EGG13874.1 - 0.45 10.4 3.0 1.2 9.0 3.0 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger FYVE PF01363.21 EGG13874.1 - 0.63 10.2 7.5 0.34 11.1 4.4 2.2 2 1 0 2 2 2 0 FYVE zinc finger Mucin PF01456.17 EGG13875.1 - 3 7.8 18.0 4.4 7.3 18.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase PF00069.25 EGG13876.1 - 4.6e-25 88.5 0.5 1.8e-24 86.6 0.5 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13876.1 - 2.2e-19 69.8 0.1 5.1e-19 68.6 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DIL PF01843.19 EGG13876.1 - 0.0058 16.9 2.9 0.0058 16.9 2.9 2.6 2 0 0 2 2 2 1 DIL domain PB1 PF00564.24 EGG13876.1 - 0.021 14.8 0.0 0.056 13.4 0.0 1.8 1 0 0 1 1 1 0 PB1 domain EF_TS PF00889.19 EGG13877.1 - 3.6e-35 121.5 1.3 9.5e-33 113.6 1.3 2.3 1 1 0 1 1 1 1 Elongation factor TS TPR_12 PF13424.6 EGG13878.1 - 5.4e-20 71.5 0.8 1.1e-07 32.0 0.0 5.7 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGG13878.1 - 2.3e-07 30.4 1.9 0.0048 16.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGG13878.1 - 3.7e-07 29.8 0.0 0.0011 18.5 0.0 3.1 2 1 0 3 3 3 2 MalT-like TPR region TPR_14 PF13428.6 EGG13878.1 - 0.00046 20.8 0.1 1.4 9.9 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG13878.1 - 0.0024 18.3 0.7 2.4 8.8 0.1 3.8 4 1 1 5 5 5 1 Tetratricopeptide repeat DNA_primase_lrg PF04104.14 EGG13878.1 - 0.0045 16.4 0.2 0.0045 16.4 0.2 1.8 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit TPR_1 PF00515.28 EGG13878.1 - 0.0087 15.9 3.5 7.7 6.5 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG13878.1 - 4.3 7.7 11.2 13 6.2 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Rap_GAP PF02145.15 EGG13879.1 - 8.9e-56 188.4 0.4 3.9e-55 186.3 0.4 2.3 1 0 0 1 1 1 1 Rap/ran-GAP DUF3384 PF11864.8 EGG13879.1 - 2.5e-33 115.7 0.6 9.6e-18 64.3 0.2 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF3384) RRM_1 PF00076.22 EGG13879.1 - 6.6e-27 93.1 1.4 1.3e-14 53.8 0.1 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tuberin PF03542.16 EGG13879.1 - 2e-24 86.4 11.8 3.7e-23 82.2 11.8 3.0 1 1 0 1 1 1 1 Tuberin RRM_7 PF16367.5 EGG13879.1 - 0.00013 22.0 0.0 0.08 13.1 0.0 3.3 2 0 0 2 2 2 2 RNA recognition motif ubiquitin PF00240.23 EGG13881.1 - 2e-18 65.9 0.3 2.8e-18 65.4 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EGG13881.1 - 6e-11 42.0 2.5 1e-10 41.3 2.5 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 EGG13881.1 - 7.6e-05 22.5 0.2 0.00014 21.7 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 EGG13881.1 - 0.016 15.0 0.2 0.028 14.2 0.2 1.3 1 0 0 1 1 1 0 UBA-like domain MSA-2c PF12238.8 EGG13881.1 - 0.026 14.5 4.9 0.033 14.2 4.9 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c C2-set PF05790.15 EGG13881.1 - 0.028 14.6 0.2 0.12 12.6 0.2 1.9 1 1 0 1 1 1 0 Immunoglobulin C2-set domain Ubiquitin_5 PF18037.1 EGG13881.1 - 0.033 14.5 0.2 0.051 13.9 0.2 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EGG13881.1 - 0.038 14.0 1.0 0.85 9.7 1.0 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 EGG13881.1 - 0.045 14.3 0.0 0.067 13.8 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain RAP1 PF07218.11 EGG13881.1 - 0.046 12.0 0.7 0.053 11.8 0.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MSP1_C PF07462.11 EGG13881.1 - 0.07 11.8 1.0 0.084 11.6 1.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Nucleo_P87 PF07267.11 EGG13881.1 - 0.1 11.4 1.1 0.12 11.2 1.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MGC-24 PF05283.11 EGG13881.1 - 0.23 11.9 4.6 0.31 11.5 4.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin XPC-binding PF09280.11 EGG13882.1 - 4.5e-21 74.3 11.3 7.1e-21 73.7 11.3 1.3 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 EGG13882.1 - 1.8e-09 37.3 0.1 4.6e-09 36.0 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain MCM_N PF14551.6 EGG13882.1 - 0.0028 18.2 0.6 0.014 15.9 0.4 2.1 1 1 1 2 2 2 1 MCM N-terminal domain BCA_ABC_TP_C PF12399.8 EGG13882.1 - 0.0077 16.1 1.4 1.8 8.6 0.1 3.6 3 0 0 3 3 3 1 Branched-chain amino acid ATP-binding cassette transporter GlnE PF03710.15 EGG13882.1 - 0.037 13.4 0.3 0.044 13.2 0.3 1.2 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase RHH_1 PF01402.21 EGG13882.1 - 0.046 13.7 1.0 0.13 12.2 0.0 2.3 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family STI1 PF17830.1 EGG13882.1 - 0.088 12.8 1.3 5.2 7.1 0.5 2.9 1 1 0 1 1 1 0 STI1 domain Thioredoxin PF00085.20 EGG13883.1 - 1e-11 44.7 0.0 2.9e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin DUF953 PF06110.11 EGG13883.1 - 0.0026 17.4 0.0 0.0062 16.2 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Ceramidase PF05875.12 EGG13883.1 - 0.064 12.7 0.4 0.082 12.3 0.4 1.2 1 0 0 1 1 1 0 Ceramidase 2TM PF13239.6 EGG13883.1 - 0.2 12.0 1.0 0.36 11.2 0.1 1.9 2 0 0 2 2 2 0 2TM domain CitMHS PF03600.16 EGG13884.1 - 0.15 11.3 7.1 0.44 9.7 7.1 1.8 1 1 0 1 1 1 0 Citrate transporter Wzz PF02706.15 EGG13884.1 - 0.18 12.1 0.2 0.18 12.1 0.2 3.6 4 0 0 4 4 4 0 Chain length determinant protein SUR7 PF06687.12 EGG13884.1 - 1.5 8.4 8.7 16 5.0 6.1 2.6 1 1 1 2 2 2 0 SUR7/PalI family HSP20 PF00011.21 EGG13885.1 - 1.1e-09 38.4 0.0 3.1e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF3203 PF11462.8 EGG13885.1 - 0.037 14.2 0.0 6.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3203) BTB PF00651.31 EGG13886.1 - 7.3e-17 61.6 0.4 7.3e-17 61.6 0.4 2.3 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 EGG13886.1 - 2.9e-09 37.1 1.1 7.5e-09 35.7 1.1 1.8 1 0 0 1 1 1 1 MATH domain BACK PF07707.15 EGG13886.1 - 7.8e-09 35.6 2.6 3.7e-08 33.4 1.0 2.7 1 1 1 2 2 2 1 BTB And C-terminal Kelch F-box-like PF12937.7 EGG13886.1 - 0.087 12.7 0.6 0.94 9.4 0.0 2.6 2 0 0 2 2 2 0 F-box-like Glyco_transf_10 PF00852.19 EGG13887.1 - 6.3e-33 114.0 4.7 1.1e-32 113.1 1.9 2.3 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Ribosomal_L34e PF01199.18 EGG13887.1 - 1.3e-24 86.3 5.6 3.2e-24 85.0 5.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L34e Glyco_tran_10_N PF17039.5 EGG13887.1 - 6.6e-12 45.9 1.3 8.7e-10 39.0 0.2 2.7 2 0 0 2 2 2 2 Fucosyltransferase, N-terminal Cupin_8 PF13621.6 EGG13888.1 - 4.2e-39 134.8 0.9 4.2e-39 134.8 0.9 2.9 2 2 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 EGG13888.1 - 2.6e-06 27.1 0.1 7e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 EGG13888.1 - 0.042 14.3 0.1 0.24 11.8 0.0 2.5 2 0 0 2 2 2 0 JmjC domain, hydroxylase BAR_3 PF16746.5 EGG13888.1 - 0.29 10.8 2.8 0.2 11.4 0.7 1.7 2 0 0 2 2 2 0 BAR domain of APPL family Oxysterol_BP PF01237.18 EGG13889.1 - 2.2e-56 191.3 0.2 3.5e-56 190.7 0.2 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein HCBP_related PF06594.11 EGG13889.1 - 0.18 11.8 4.1 0.77 9.8 0.1 3.2 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain GCN5L1 PF06320.13 EGG13890.1 - 0.0014 18.8 1.4 0.0024 18.0 0.8 1.7 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) JAB PF01398.21 EGG13890.1 - 0.047 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PrkA PF06798.12 EGG13890.1 - 0.049 13.3 0.2 0.11 12.2 0.2 1.7 1 1 0 1 1 1 0 PrkA serine protein kinase C-terminal domain PEPcase PF00311.17 EGG13890.1 - 0.051 11.6 0.2 0.071 11.2 0.2 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase RAI16-like PF10257.9 EGG13890.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein UPF0149 PF03695.13 EGG13890.1 - 0.16 12.2 2.8 1.1 9.5 1.0 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0149) Methyltransf_31 PF13847.6 EGG13891.1 - 2.3e-19 69.7 0.1 3.1e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG13891.1 - 3.8e-15 56.4 0.0 7e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG13891.1 - 5.4e-14 52.6 0.0 8.5e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG13891.1 - 5.8e-11 42.5 0.0 8.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG13891.1 - 1.8e-10 41.5 0.1 3e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG13891.1 - 3.3e-09 36.5 0.0 4.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EGG13891.1 - 4.7e-08 32.7 0.1 6.4e-08 32.2 0.1 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 EGG13891.1 - 2.7e-06 26.9 0.1 3.8e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EGG13891.1 - 6e-05 22.6 0.1 0.0001 21.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EGG13891.1 - 0.00019 21.5 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGG13891.1 - 0.00054 19.3 0.0 0.00068 19.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 EGG13891.1 - 0.00059 19.0 0.0 0.00082 18.5 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_18 PF12847.7 EGG13891.1 - 0.0035 17.3 0.2 0.0049 16.8 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 EGG13891.1 - 0.0065 15.6 0.4 0.019 14.1 0.4 1.8 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_9 PF08003.11 EGG13891.1 - 0.0084 15.1 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DOT1 PF08123.13 EGG13891.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 UPF0020 PF01170.18 EGG13891.1 - 0.028 14.1 0.1 0.056 13.1 0.1 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF4213 PF13938.6 EGG13891.1 - 0.042 14.1 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative heavy-metal chelation FtsJ PF01728.19 EGG13891.1 - 0.044 13.9 0.1 0.099 12.8 0.1 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 EGG13891.1 - 0.046 13.5 0.0 0.088 12.5 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AviRa PF11599.8 EGG13891.1 - 0.1 12.0 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa DUF43 PF01861.16 EGG13891.1 - 0.12 11.5 1.1 0.13 11.4 0.1 1.5 2 0 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain TMEM144 PF07857.12 EGG13892.1 - 4.8e-83 278.9 18.9 5.7e-83 278.7 18.9 1.1 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters FYVE PF01363.21 EGG13892.1 - 4.5e-22 78.0 12.4 7e-22 77.4 12.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger Sugar_transport PF06800.12 EGG13892.1 - 3.4e-08 33.1 20.9 1e-07 31.6 6.9 2.7 2 1 0 2 2 2 2 Sugar transport protein FYVE_2 PF02318.16 EGG13892.1 - 0.00035 20.8 6.8 0.00059 20.0 6.8 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger DUF5357 PF17310.2 EGG13892.1 - 2.3 6.7 4.4 0.4 9.2 0.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5357) C1_1 PF00130.22 EGG13892.1 - 3.5 7.6 12.9 0.9 9.5 9.7 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LRR_8 PF13855.6 EGG13893.1 - 0.0014 18.3 1.8 0.0014 18.3 1.8 8.4 8 1 0 8 8 8 4 Leucine rich repeat TPR_8 PF13181.6 EGG13893.1 - 0.0016 18.5 0.1 0.69 10.3 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3458 PF11940.8 EGG13893.1 - 0.066 13.7 0.0 0.36 11.3 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Ig-like fold LRR_6 PF13516.6 EGG13893.1 - 0.14 12.3 0.0 0.14 12.3 0.0 9.2 12 0 0 12 12 12 0 Leucine Rich repeat TPR_2 PF07719.17 EGG13893.1 - 0.15 12.2 0.1 1.1 9.5 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PhoU PF01895.19 EGG13893.1 - 8.2 7.0 8.3 0.93 10.0 1.5 3.1 2 1 0 2 2 2 0 PhoU domain BAR_3 PF16746.5 EGG13894.1 - 1.8e-07 31.1 3.5 2.6e-07 30.6 3.5 1.1 1 0 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 EGG13894.1 - 3.9e-05 23.4 3.5 5.4e-05 23.0 3.5 1.2 1 0 0 1 1 1 1 BAR domain Na_H_Exchanger PF00999.21 EGG13895.1 - 4.9e-59 200.0 51.9 4.9e-59 200.0 51.9 1.9 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family Pex24p PF06398.11 EGG13895.1 - 0.0027 16.8 1.1 0.0027 16.8 1.1 2.4 4 0 0 4 4 4 1 Integral peroxisomal membrane peroxin ESSS PF10183.9 EGG13895.1 - 0.17 12.1 1.0 0.79 10.0 0.0 2.7 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4501 PF14946.6 EGG13895.1 - 1.3 9.1 3.5 0.62 10.1 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4501) DFP PF04127.15 EGG13896.1 - 5.4e-17 62.2 0.0 2.6e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein RabGAP-TBC PF00566.18 EGG13897.1 - 4.8e-29 101.5 14.9 6.5e-15 55.4 1.4 2.5 2 1 0 2 2 2 2 Rab-GTPase-TBC domain MAT1-1-2 PF17043.5 EGG13897.1 - 0.023 14.5 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 Mating type protein 1-1-2 of unknown function RICTOR_phospho PF14665.6 EGG13898.1 - 0.00035 20.9 0.9 0.0025 18.1 0.1 2.2 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, phosphorylation-site OrfB_Zn_ribbon PF07282.11 EGG13900.1 - 1e-05 25.4 0.0 0.0038 17.1 0.0 3.0 2 0 0 2 2 2 1 Putative transposase DNA-binding domain LRR_9 PF14580.6 EGG13900.1 - 1.1e-05 25.0 0.1 2.6e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat Ion_trans PF00520.31 EGG13900.1 - 1.3e-05 24.5 5.2 2.4e-05 23.7 5.2 1.3 1 0 0 1 1 1 1 Ion transport protein LRR_8 PF13855.6 EGG13900.1 - 1.3e-05 24.8 0.4 3.8e-05 23.4 0.4 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EGG13900.1 - 0.0013 19.1 0.5 0.067 13.6 0.2 3.1 1 1 0 2 2 2 1 Leucine Rich repeats (2 copies) HALZ PF02183.18 EGG13900.1 - 0.42 10.9 4.4 0.95 9.7 4.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF2992 PF11208.8 EGG13900.1 - 0.94 9.7 0.0 0.94 9.7 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2992) Mito_carr PF00153.27 EGG13901.1 - 1.3e-10 41.1 0.7 0.0006 19.7 0.0 3.0 3 1 0 3 3 3 2 Mitochondrial carrier protein Tmemb_9 PF05434.11 EGG13901.1 - 0.11 12.3 0.0 0.43 10.5 0.0 2.0 1 1 0 1 1 1 0 TMEM9 Mre11_DNA_bind PF04152.14 EGG13901.1 - 0.24 11.7 2.4 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain C2 PF00168.30 EGG13902.1 - 6.1e-23 81.1 0.5 1.6e-22 79.7 0.1 1.9 2 0 0 2 2 2 1 C2 domain DUF1464 PF07318.12 EGG13902.1 - 0.039 13.1 0.1 0.051 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Terpene_synth_C PF03936.16 EGG13903.1 - 0.0013 18.1 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain EGF_2 PF07974.13 EGG13904.1 - 0.56 10.6 29.9 0.25 11.7 10.0 2.6 2 0 0 2 2 2 0 EGF-like domain Terpene_synth_C PF03936.16 EGG13905.1 - 0.025 14.0 0.2 0.04 13.3 0.2 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Thioredoxin PF00085.20 EGG13906.1 - 1.9e-07 31.0 0.0 2.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGG13906.1 - 0.0003 21.0 0.2 0.0013 19.0 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 EGG13906.1 - 0.019 15.2 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin UPF0047 PF01894.17 EGG13906.1 - 0.16 12.1 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 Phosducin PF02114.16 EGG13907.1 - 0.0044 16.0 0.0 0.0047 15.9 0.0 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin_2 PF13098.6 EGG13907.1 - 0.042 14.3 0.1 0.042 14.3 0.1 1.5 2 0 0 2 2 2 0 Thioredoxin-like domain Pirin PF02678.16 EGG13908.1 - 5.7e-34 116.3 0.4 1.5e-33 115.0 0.4 1.8 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGG13908.1 - 3.6e-21 75.5 0.0 2.4e-20 72.8 0.0 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cation_ATPase_C PF00689.21 EGG13908.1 - 5.9e-08 32.6 12.7 5.9e-08 32.6 12.7 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGG13908.1 - 6.9e-06 25.7 2.4 1.7e-05 24.4 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_6 PF13344.6 EGG13908.1 - 0.018 15.2 0.0 0.057 13.5 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG13908.1 - 0.02 15.2 0.0 0.13 12.5 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase KOW PF00467.29 EGG13908.1 - 0.051 13.6 2.2 0.062 13.3 0.6 2.0 2 0 0 2 2 2 0 KOW motif Methyltransf_12 PF08242.12 EGG13909.1 - 0.014 16.1 0.0 0.038 14.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 EGG13909.1 - 0.017 14.3 0.4 0.032 13.4 0.4 1.4 1 0 0 1 1 1 0 O-methyltransferase DOT1 PF08123.13 EGG13909.1 - 0.028 13.9 0.7 0.17 11.4 0.7 2.1 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_15 PF09445.10 EGG13909.1 - 0.035 13.7 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 EGG13909.1 - 0.039 13.9 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Phosducin PF02114.16 EGG13910.1 - 0.00088 18.3 0.0 0.00088 18.3 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_2 PF13098.6 EGG13910.1 - 0.051 14.0 0.2 0.051 14.0 0.2 1.5 2 0 0 2 2 2 0 Thioredoxin-like domain Tom22 PF04281.13 EGG13911.1 - 0.041 13.7 0.1 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PH PF00169.29 EGG13912.1 - 2.9e-11 43.8 2.0 3.6e-11 43.5 0.1 2.1 2 1 0 2 2 2 1 PH domain PH_11 PF15413.6 EGG13912.1 - 0.021 15.2 2.2 0.021 15.2 2.2 2.8 2 2 0 2 2 2 0 Pleckstrin homology domain Macoilin PF09726.9 EGG13912.1 - 7.3 5.0 15.7 9.9 4.6 15.7 1.2 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 EGG13912.1 - 9.7 5.7 16.1 0.12 12.0 8.0 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HD_3 PF13023.6 EGG13913.1 - 5.7e-42 143.4 0.5 7.1e-42 143.1 0.5 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EGG13913.1 - 1.1e-13 51.3 0.3 1.3e-13 51.1 0.3 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EGG13913.1 - 9.9e-05 22.6 0.1 0.00044 20.5 0.1 1.8 1 1 0 1 1 1 1 HD domain NOA36 PF06524.12 EGG13914.1 - 0.0067 15.8 6.5 0.0067 15.8 6.5 1.1 1 0 0 1 1 1 1 NOA36 protein Myc_N PF01056.18 EGG13914.1 - 0.015 15.2 1.9 0.015 15.2 1.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Methyltransf_12 PF08242.12 EGG13914.1 - 0.065 14.0 0.3 0.088 13.6 0.3 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cwf_Cwc_15 PF04889.12 EGG13914.1 - 0.29 10.8 12.3 0.33 10.6 12.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 EGG13914.1 - 0.86 7.6 5.8 0.83 7.7 5.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 EGG13914.1 - 2.5 7.7 6.6 3.3 7.4 6.6 1.2 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.16 EGG13914.1 - 6.2 5.9 10.0 8 5.6 10.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit AFG1_ATPase PF03969.16 EGG13915.1 - 8.2e-104 347.4 2.9 2e-99 332.9 0.3 2.8 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EGG13915.1 - 0.0024 18.3 0.2 0.29 11.5 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 EGG13915.1 - 0.043 14.2 1.3 0.39 11.1 0.0 3.2 4 1 0 4 4 4 0 RNA helicase AAA_22 PF13401.6 EGG13915.1 - 0.048 13.9 0.1 0.39 11.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 EGG13916.1 - 1.7e-63 213.7 0.0 2.5e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGG13916.1 - 3.4e-28 97.8 0.0 6.4e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EGG13916.1 - 2.1e-20 72.6 0.0 1.3e-19 70.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGG13916.1 - 9.3e-16 58.0 0.3 3.6e-15 56.1 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGG13916.1 - 2.7e-13 49.8 0.0 6.9e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II PAD_M PF08527.10 EGG13916.1 - 0.0013 18.4 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain MMR_HSR1 PF01926.23 EGG13916.1 - 0.0047 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TetR_C_25 PF17933.1 EGG13916.1 - 0.12 12.8 0.0 0.93 9.8 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TFIIA PF03153.13 EGG13919.1 - 0.027 14.5 20.3 0.037 14.0 20.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acetyltransf_6 PF13480.7 EGG13919.1 - 0.28 11.4 0.6 0.52 10.4 0.6 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mt_ATP-synt_D PF05873.12 EGG13919.1 - 6.5 6.6 17.7 4.5 7.1 13.5 2.4 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) RNase_T PF00929.24 EGG13920.1 - 7.1e-12 46.2 0.1 1.5e-11 45.1 0.1 1.6 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 EGG13920.1 - 0.00032 20.7 2.0 0.00068 19.6 0.0 2.3 2 0 0 2 2 2 1 3' exoribonuclease, RNase T-like EPL1 PF10513.9 EGG13920.1 - 0.0095 16.3 1.8 0.01 16.2 0.4 1.8 2 0 0 2 2 2 1 Enhancer of polycomb-like Spt20 PF12090.8 EGG13920.1 - 0.018 14.7 22.0 0.033 13.8 18.3 2.6 3 0 0 3 3 3 0 Spt20 family Ufd2P_core PF10408.9 EGG13920.1 - 0.019 13.6 7.5 0.032 12.9 7.5 1.2 1 0 0 1 1 1 0 Ubiquitin elongating factor core CNDH2_M PF16869.5 EGG13920.1 - 0.033 14.9 0.3 0.059 14.1 0.3 1.5 1 0 0 1 1 1 0 PF16858 Med15 PF09606.10 EGG13920.1 - 0.052 12.3 13.2 0.068 11.9 13.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF5385 PF17359.2 EGG13920.1 - 0.089 12.3 7.2 0.088 12.4 3.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5385) TFIIA PF03153.13 EGG13920.1 - 0.095 12.7 12.9 0.18 11.8 12.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ThiD2 PF17792.1 EGG13920.1 - 0.11 12.9 1.8 0.28 11.6 1.8 1.6 1 0 0 1 1 1 0 ThiD2 family DNA_pol_A_exo1 PF01612.20 EGG13920.1 - 0.13 12.0 4.3 1.8 8.3 0.0 2.8 3 0 0 3 3 3 0 3'-5' exonuclease DUF702 PF05142.12 EGG13920.1 - 0.14 12.6 3.6 0.099 13.1 1.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF702) SpoVR PF04293.13 EGG13920.1 - 0.27 9.9 5.2 0.58 8.8 5.2 1.5 1 0 0 1 1 1 0 SpoVR like protein DUF4834 PF16118.5 EGG13920.1 - 2.2 9.3 8.7 2.9 8.9 6.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DSHCT PF08148.12 EGG13921.1 - 8.3e-46 155.6 0.6 8.3e-46 155.6 0.6 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 EGG13921.1 - 6.8e-31 108.2 2.9 6.8e-31 108.2 2.9 2.4 2 1 0 2 2 2 1 rRNA-processing arch domain DEAD PF00270.29 EGG13921.1 - 3.8e-17 62.6 0.0 9.1e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ski2_N PF17911.1 EGG13921.1 - 2e-15 56.8 0.0 2e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 Ski2 N-terminal region Helicase_C PF00271.31 EGG13921.1 - 4e-06 27.2 0.1 5.6e-05 23.4 0.1 2.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain MAT1 PF06391.13 EGG13921.1 - 0.34 10.7 19.5 0.039 13.8 14.5 2.0 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 CagX PF03524.15 EGG13921.1 - 0.86 9.3 3.3 0.3 10.8 0.1 1.8 2 0 0 2 2 2 0 Conjugal transfer protein PI3K_1B_p101 PF10486.9 EGG13921.1 - 2 6.1 11.9 3.7 5.2 11.9 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIF_alpha PF05793.12 EGG13921.1 - 7.1 5.1 20.3 12 4.3 20.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAD-oxidase_C PF02913.19 EGG13922.1 - 1.9e-49 168.6 0.0 2.4e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGG13922.1 - 5.1e-37 126.7 0.2 8.7e-37 126.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain EFG_II PF14492.6 EGG13922.1 - 0.1 12.7 0.0 0.61 10.2 0.0 2.2 2 0 0 2 2 2 0 Elongation Factor G, domain II Pkinase PF00069.25 EGG13923.1 - 5.4e-69 232.5 0.0 5.4e-69 232.5 0.0 2.6 3 0 0 3 3 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG13923.1 - 2.3e-46 158.2 0.3 7.5e-46 156.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG13923.1 - 1.3e-08 34.0 0.1 1.3e-08 34.0 0.1 3.1 2 1 0 2 2 1 1 Fungal protein kinase ARGLU PF15346.6 EGG13923.1 - 0.012 15.5 31.1 0.032 14.1 10.3 2.6 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Kdo PF06293.14 EGG13923.1 - 0.019 14.3 0.0 0.019 14.3 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP-synt_G PF04718.15 EGG13923.1 - 0.06 14.2 0.4 8.1 7.3 0.0 3.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit FTA2 PF13095.6 EGG13923.1 - 0.094 12.3 0.0 0.094 12.3 0.0 2.9 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 OmpH PF03938.14 EGG13923.1 - 0.71 10.2 26.0 0.54 10.6 9.8 2.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) EMC3_TMCO1 PF01956.16 EGG13923.1 - 0.82 9.4 14.5 1.5 8.6 2.6 2.6 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF4337 PF14235.6 EGG13923.1 - 1.4 9.0 20.5 0.17 12.0 4.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF2052 PF09747.9 EGG13923.1 - 2.3 8.3 17.6 2.7 8.1 6.0 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF1848 PF08902.11 EGG13923.1 - 4.5 6.9 8.8 0.16 11.7 2.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) KfrA_N PF11740.8 EGG13923.1 - 7.5 7.3 10.5 10 6.9 4.7 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF1682 PF07946.14 EGG13923.1 - 8.5 5.5 29.0 0.076 12.2 7.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Atrophin-1 PF03154.15 EGG13923.1 - 8.6 4.5 15.9 0.21 9.9 4.7 2.2 2 0 0 2 2 2 0 Atrophin-1 family Adap_comp_sub PF00928.21 EGG13924.1 - 3.2e-62 210.3 2.3 4.4e-62 209.9 2.3 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGG13924.1 - 1.2e-07 31.7 0.7 2.4e-07 30.8 0.7 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LRR_9 PF14580.6 EGG13925.1 - 1.8e-08 34.1 0.3 4.5e-08 32.8 0.3 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGG13925.1 - 3.6e-08 33.6 12.4 3.7e-06 27.2 1.1 5.2 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG13925.1 - 2.1e-06 27.4 13.2 0.00041 20.0 2.0 4.2 2 1 0 3 3 3 2 Leucine rich repeat CG-1 PF03859.16 EGG13925.1 - 0.024 14.4 0.1 0.091 12.6 0.1 2.0 1 0 0 1 1 1 0 CG-1 domain LRR_1 PF00560.33 EGG13925.1 - 0.11 13.1 9.1 46 5.1 0.1 6.8 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EGG13925.1 - 1.1 9.5 13.4 15 6.0 0.5 5.6 5 0 0 5 5 5 0 Leucine Rich repeat Creatinase_N_2 PF16189.5 EGG13926.1 - 1e-53 181.7 2.4 2.3e-51 174.1 0.1 3.0 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EGG13926.1 - 5.7e-39 134.0 0.0 8e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EGG13926.1 - 4.8e-25 88.7 0.0 1e-20 74.8 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EGG13926.1 - 2.4e-19 69.1 0.8 8e-19 67.5 0.2 2.3 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 UQ_con PF00179.26 EGG13927.1 - 2.4e-27 95.3 0.5 6e-27 94.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Nop14 PF04147.12 EGG13927.1 - 0.00047 18.5 41.2 0.033 12.4 19.6 2.2 2 0 0 2 2 2 2 Nop14-like family SDA1 PF05285.12 EGG13927.1 - 0.00066 19.2 44.8 0.052 13.0 22.4 2.3 2 0 0 2 2 2 2 SDA1 UEV PF05743.13 EGG13927.1 - 0.0013 18.6 0.1 0.0027 17.6 0.1 1.5 1 0 0 1 1 1 1 UEV domain CDC45 PF02724.14 EGG13927.1 - 0.0014 17.0 32.0 0.036 12.4 13.3 2.2 2 0 0 2 2 2 2 CDC45-like protein Prok-E2_B PF14461.6 EGG13927.1 - 0.066 12.9 0.1 0.39 10.4 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic E2 family B Presenilin PF01080.17 EGG13927.1 - 7.5 5.2 12.7 6.4 5.4 1.6 2.2 2 0 0 2 2 2 0 Presenilin TnpW PF14202.6 EGG13929.1 - 0.13 12.2 1.2 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 Transposon-encoded protein TnpW SAC3_GANP PF03399.16 EGG13930.1 - 2.2e-62 211.1 1.0 4.1e-62 210.2 1.0 1.4 1 0 0 1 1 1 1 SAC3/GANP family RRM_1 PF00076.22 EGG13930.1 - 0.00015 21.5 0.1 0.00056 19.7 0.1 2.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRA1 PF03208.19 EGG13931.1 - 9.6e-27 93.4 2.0 1.4e-26 92.8 2.0 1.2 1 0 0 1 1 1 1 PRA1 family protein DUF1418 PF07214.12 EGG13931.1 - 0.089 12.7 1.2 0.17 11.8 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) Rep_trans PF02486.19 EGG13931.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Replication initiation factor DPM3 PF08285.11 EGG13931.1 - 1.9 8.7 5.0 1.9 8.7 4.0 1.5 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2207 PF09972.9 EGG13931.1 - 3.6 6.3 7.1 9.9 4.8 7.1 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) GDPD PF03009.17 EGG13932.1 - 5.4e-50 170.5 0.0 3e-48 164.8 0.0 2.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 EGG13932.1 - 2e-17 62.9 0.1 4.8e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Starch binding domain HEAT_2 PF13646.6 EGG13933.1 - 2.7e-40 136.6 16.4 8.4e-16 58.1 0.6 3.5 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 EGG13933.1 - 4.7e-31 104.3 4.0 1.6e-05 25.2 0.1 6.3 6 0 0 6 6 6 6 PBS lyase HEAT-like repeat HEAT PF02985.22 EGG13933.1 - 1.5e-11 43.5 4.3 0.01 16.1 0.1 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 EGG13933.1 - 2.3e-07 31.2 3.6 0.027 15.0 0.2 4.2 4 0 0 4 4 4 3 HEAT-like repeat Arm PF00514.23 EGG13933.1 - 4.7e-05 23.3 1.3 0.27 11.3 0.0 3.4 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat Vitellogenin_N PF01347.22 EGG13933.1 - 0.0011 17.4 0.3 0.017 13.5 0.1 2.0 2 0 0 2 2 2 1 Lipoprotein amino terminal region TAF6_C PF07571.13 EGG13933.1 - 0.014 15.7 0.3 3.1 8.2 0.0 3.8 3 1 1 4 4 4 0 TAF6 C-terminal HEAT repeat domain Chorismate_bind PF00425.18 EGG13933.1 - 0.018 14.6 0.6 0.059 12.9 0.1 1.9 2 0 0 2 2 2 0 chorismate binding enzyme Cnd1 PF12717.7 EGG13933.1 - 0.043 13.9 4.0 1.4 9.0 0.1 3.9 3 2 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Tubulin PF00091.25 EGG13934.1 - 5.6e-37 127.9 0.2 5.6e-37 127.9 0.2 2.0 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 EGG13934.1 - 8.9e-30 102.9 1.7 2.2e-29 101.6 1.7 1.7 1 0 0 1 1 1 1 FtsZ family, C-terminal domain TFIIA PF03153.13 EGG13934.1 - 0.34 10.9 37.7 0.48 10.4 37.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 2OG-FeII_Oxy_2 PF13532.6 EGG13935.1 - 2.6e-29 102.8 0.2 5.2e-29 101.8 0.2 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1948 PF09185.10 EGG13935.1 - 0.34 10.8 5.9 0.2 11.5 3.6 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1948) adh_short PF00106.25 EGG13936.1 - 2.1e-50 170.9 0.6 2.6e-50 170.6 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG13936.1 - 2.1e-32 112.5 0.0 2.7e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG13936.1 - 1.4e-08 34.8 2.5 7.3e-08 32.5 2.5 1.9 1 1 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 EGG13936.1 - 0.00085 18.6 0.1 0.0013 18.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.15 EGG13936.1 - 0.0018 17.4 0.3 0.0031 16.7 0.3 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGG13936.1 - 0.0044 16.5 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG13936.1 - 0.0071 15.8 0.0 0.052 12.9 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Pyr_redox PF00070.27 EGG13936.1 - 0.018 15.6 0.1 0.043 14.4 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.19 EGG13936.1 - 0.033 13.5 0.1 0.061 12.6 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 EGG13936.1 - 0.12 11.9 0.5 0.28 10.7 0.3 1.6 2 0 0 2 2 2 0 NmrA-like family Epimerase PF01370.21 EGG13937.1 - 6e-18 65.2 0.0 8.6e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGG13937.1 - 1.5e-13 50.5 0.0 2.1e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGG13937.1 - 3.1e-06 26.6 0.0 1.3e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EGG13937.1 - 1.1e-05 25.0 0.0 7.3e-05 22.3 0.0 1.9 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EGG13937.1 - 0.026 14.8 0.1 0.92 9.8 0.0 2.6 1 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain LRR_4 PF12799.7 EGG13938.1 - 6.9e-28 96.3 42.3 1.2e-05 25.6 0.2 7.5 3 2 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG13938.1 - 3.2e-24 84.4 40.7 1.6e-08 34.2 0.8 6.8 2 2 4 7 7 7 7 Leucine rich repeat Filamin PF00630.19 EGG13938.1 - 1.6e-09 38.5 0.0 2.7e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Filamin/ABP280 repeat LRR_1 PF00560.33 EGG13938.1 - 4.7e-08 32.5 31.9 3.3 8.6 0.2 10.5 9 2 0 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 EGG13938.1 - 2.3e-05 24.1 36.5 2.8 8.2 0.2 10.2 10 0 0 10 10 10 3 Leucine Rich repeat LRR_9 PF14580.6 EGG13938.1 - 0.001 18.6 18.7 0.39 10.2 0.2 4.5 1 1 4 5 5 5 3 Leucine-rich repeat RRM_1 PF00076.22 EGG13939.1 - 8e-51 169.8 0.1 2.2e-22 78.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG13939.1 - 2.9e-05 24.1 0.0 0.039 14.1 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif DbpA PF03880.15 EGG13939.1 - 0.091 12.8 0.0 23 5.1 0.0 2.5 2 0 0 2 2 2 0 DbpA RNA binding domain CsbD PF05532.12 EGG13940.1 - 0.00044 20.1 1.2 0.00081 19.2 1.2 1.3 1 0 0 1 1 1 1 CsbD-like Med11 PF10280.9 EGG13940.1 - 0.0094 16.4 6.0 0.0094 16.4 6.0 2.8 2 2 0 2 2 2 1 Mediator complex protein DUF3835 PF12927.7 EGG13940.1 - 0.11 13.3 0.8 0.45 11.4 0.8 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) Coiled PF05710.12 EGG13941.1 - 4.9e-21 75.4 21.8 5.6e-21 75.2 21.8 1.0 1 0 0 1 1 1 1 Coiled coil Cupin_4 PF08007.12 EGG13942.1 - 3.4e-66 223.9 0.1 4.4e-66 223.5 0.1 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 EGG13942.1 - 1.3e-08 34.9 0.1 1.3e-06 28.4 0.1 2.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 EGG13942.1 - 0.00076 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EGG13942.1 - 0.0064 16.2 0.0 0.041 13.6 0.0 2.2 2 0 0 2 2 2 1 Cupin domain EXS PF03124.14 EGG13943.1 - 1.1e-60 205.7 24.3 1.1e-60 205.7 24.3 1.6 2 0 0 2 2 2 1 EXS family DUF373 PF04123.13 EGG13943.1 - 2.2 7.7 15.7 1.8 7.9 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF373) COX2_TM PF02790.15 EGG13943.1 - 2.8 8.2 16.6 1.3 9.2 3.3 3.3 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain HSP70 PF00012.20 EGG13944.1 - 1.7e-42 145.4 0.0 3.3e-42 144.5 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein Actin PF00022.19 EGG13945.1 - 1.9e-152 507.6 0.0 6e-152 506.0 0.0 1.6 1 1 0 1 1 1 1 Actin SAPS PF04499.15 EGG13946.1 - 9.8e-09 34.5 0.2 9.8e-09 34.5 0.2 7.9 3 2 2 5 5 5 3 SIT4 phosphatase-associated protein Rcd1 PF04078.13 EGG13946.1 - 0.016 14.5 0.3 0.037 13.3 0.3 1.6 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like RabGAP-TBC PF00566.18 EGG13947.1 - 5e-44 150.5 14.2 2.3e-42 145.1 14.2 2.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain LOH1CR12 PF10158.9 EGG13947.1 - 4.2e-06 26.8 1.5 1.2e-05 25.3 1.5 1.7 1 0 0 1 1 1 1 Tumour suppressor protein Fibin PF15819.5 EGG13947.1 - 0.0029 17.4 0.5 0.0029 17.4 0.5 1.8 2 0 0 2 2 2 1 Fin bud initiation factor homologue UPF0515 PF15135.6 EGG13947.1 - 0.12 11.7 6.7 0.069 12.5 0.7 2.4 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 Chromosome_seg PF13889.6 EGG13948.1 - 3.2e-20 72.0 2.6 7.6e-20 70.8 2.6 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 EGG13948.1 - 2e-12 47.5 0.1 5.2e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) ATG13 PF10033.9 EGG13948.1 - 0.019 14.7 1.6 0.081 12.6 1.6 2.1 1 1 0 1 1 1 0 Autophagy-related protein 13 Myosin_head PF00063.21 EGG13950.1 - 1.5e-269 895.9 0.1 2.2e-269 895.3 0.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGG13950.1 - 1.4e-42 145.5 4.2 2.5e-42 144.7 4.2 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 EGG13950.1 - 8.3e-17 60.8 0.2 1.8e-16 59.7 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGG13950.1 - 4.7e-16 58.1 0.2 9.4e-16 57.2 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG13950.1 - 3.9e-12 45.7 0.0 1.1e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain Sld5 PF05916.11 EGG13950.1 - 2.4e-06 27.9 1.8 1.6e-05 25.3 1.5 2.4 2 0 0 2 2 2 1 GINS complex protein AAA_16 PF13191.6 EGG13950.1 - 0.0018 18.7 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain IQ PF00612.27 EGG13950.1 - 0.029 14.1 0.1 0.081 12.8 0.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Zeta_toxin PF06414.12 EGG13950.1 - 0.032 13.5 0.0 0.081 12.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 EGG13950.1 - 0.035 14.4 0.1 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGG13950.1 - 0.05 13.3 0.1 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 EGG13950.1 - 0.055 14.0 0.6 0.26 11.8 0.0 2.4 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 EGG13950.1 - 0.18 11.7 0.1 3.9 7.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain RabGAP-TBC PF00566.18 EGG13951.1 - 1.2e-54 185.2 3.4 1.2e-54 185.2 3.4 3.6 2 1 2 4 4 4 1 Rab-GTPase-TBC domain SUIM_assoc PF16619.5 EGG13951.1 - 0.00014 21.8 3.5 0.00014 21.8 3.5 3.3 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 COG2 PF06148.11 EGG13952.1 - 7.2e-32 110.3 2.7 7.2e-32 110.3 2.7 3.5 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 EGG13952.1 - 1.3e-30 106.4 0.1 1.3e-30 106.4 0.1 4.5 5 2 1 6 6 6 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 EGG13952.1 - 4.4e-05 23.5 0.0 4.4e-05 23.5 0.0 4.7 4 2 0 4 4 4 1 Vps51/Vps67 SKA1 PF07160.12 EGG13952.1 - 0.023 14.6 0.5 0.023 14.6 0.5 3.5 5 0 0 5 5 5 0 Spindle and kinetochore-associated protein 1 COG5 PF10392.9 EGG13952.1 - 0.036 14.2 0.4 0.036 14.2 0.4 4.5 4 2 1 5 5 5 0 Golgi transport complex subunit 5 HSDR_N_2 PF13588.6 EGG13952.1 - 0.043 13.8 2.5 2.4 8.2 1.0 3.0 3 0 0 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) SUIM_assoc PF16619.5 EGG13952.1 - 1.8 8.7 8.3 16 5.6 0.2 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 BP28CT PF08146.12 EGG13952.1 - 9.7 6.0 10.4 0.37 10.6 0.4 3.4 4 0 0 4 4 4 0 BP28CT (NUC211) domain Ank_2 PF12796.7 EGG13955.1 - 8e-34 116.1 3.1 2e-13 50.7 0.2 5.0 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG13955.1 - 1.6e-25 89.1 6.8 3.6e-07 30.6 0.0 6.4 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG13955.1 - 2.7e-24 84.9 4.9 7.1e-06 26.2 0.0 7.0 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG13955.1 - 2.8e-24 82.5 7.1 3.4e-06 27.0 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 EGG13955.1 - 1.2e-19 69.8 6.6 3.4e-05 24.1 0.0 7.5 6 1 1 7 7 7 4 Ankyrin repeat Coilin_N PF15862.5 EGG13955.1 - 0.0089 15.8 0.3 0.0089 15.8 0.3 3.9 3 1 0 3 3 3 1 Coilin N-terminus SPA PF08616.10 EGG13957.1 - 8e-34 116.0 0.0 1.2e-32 112.3 0.0 2.6 2 0 0 2 2 2 1 Stabilization of polarity axis Afi1 PF07792.12 EGG13957.1 - 7.2e-21 75.1 1.3 7.2e-21 75.1 1.3 3.4 2 1 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 EGG13957.1 - 4.8e-12 45.3 0.1 0.00054 18.8 0.0 3.7 2 1 0 3 3 3 3 Transport protein Avl9 DUF2347 PF09804.9 EGG13957.1 - 1.2e-07 31.6 0.0 0.00053 19.7 0.0 3.3 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) EST1 PF10374.9 EGG13957.1 - 5 7.8 6.1 0.32 11.6 0.4 2.0 2 0 0 2 2 2 0 Telomerase activating protein Est1 PPR PF01535.20 EGG13958.1 - 0.028 14.6 0.4 23 5.5 0.0 3.7 4 0 0 4 4 4 0 PPR repeat Pdase_M17_N2 PF18295.1 EGG13958.1 - 0.18 12.0 2.5 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 DUF4407 PF14362.6 EGG13958.1 - 0.85 8.9 10.0 0.56 9.5 8.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Glycolytic PF00274.19 EGG13959.1 - 8e-165 547.7 0.0 9e-165 547.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Ydr279_N PF17745.1 EGG13960.1 - 5e-10 39.5 0.5 1.2e-09 38.3 0.2 1.9 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 EGG13960.1 - 2.5e-07 31.0 0.4 7.8e-07 29.4 0.4 1.9 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain YL1 PF05764.13 EGG13960.1 - 1.4 9.0 9.6 2.2 8.3 9.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Aldedh PF00171.22 EGG13961.1 - 4.8e-133 444.0 0.0 5.9e-133 443.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGG13961.1 - 0.012 14.6 0.8 0.24 10.4 0.7 2.3 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Transgly_assoc PF04226.13 EGG13961.1 - 0.047 13.9 0.6 0.12 12.7 0.6 1.7 1 0 0 1 1 1 0 Transglycosylase associated protein OmdA PF13376.6 EGG13961.1 - 0.17 12.0 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated FA_hydroxylase PF04116.13 EGG13962.1 - 3.9e-29 101.7 12.7 3.9e-29 101.7 12.7 1.9 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily DHHC PF01529.20 EGG13962.1 - 0.72 10.0 5.2 0.16 12.0 0.4 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase FTHFS PF01268.19 EGG13963.1 - 3.1e-258 857.5 0.0 3.6e-258 857.3 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase CbiA PF01656.23 EGG13963.1 - 0.069 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Dicty_REP PF05086.12 EGG13964.1 - 6 4.7 30.6 0.028 12.4 10.1 2.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Med13_C PF06333.12 EGG13964.1 - 6.5 5.9 33.8 3.9 6.7 10.5 2.4 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Glyco_hydro_38N PF01074.22 EGG13965.1 - 5.4e-76 255.7 2.4 1.4e-75 254.4 2.4 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGG13965.1 - 2.6e-16 60.4 0.1 2.6e-16 60.4 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGG13965.1 - 7.2e-15 54.9 0.1 1.7e-14 53.7 0.1 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EGG13965.1 - 1.7e-09 37.6 0.5 9e-09 35.3 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DUF4834 PF16118.5 EGG13965.1 - 0.092 13.7 0.6 0.23 12.4 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 EGG13965.1 - 0.28 10.8 10.3 0.63 9.6 10.3 1.6 1 0 0 1 1 1 0 Spt20 family DUF5336 PF17270.2 EGG13965.1 - 4.3 6.9 5.7 3.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5336) PH PF00169.29 EGG13966.1 - 1e-16 61.3 0.1 1e-16 61.3 0.1 3.2 2 1 1 3 3 3 1 PH domain PH_8 PF15409.6 EGG13966.1 - 1.5e-05 25.2 0.0 4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain TCRP1 PF14944.6 EGG13966.1 - 0.055 13.4 0.0 0.055 13.4 0.0 2.5 2 1 0 2 2 2 0 Tongue Cancer Chemotherapy Resistant Protein 1 PH_9 PF15410.6 EGG13966.1 - 1.6 9.1 0.0 1.6 9.1 0.0 3.7 4 0 0 4 4 4 0 Pleckstrin homology domain SAP PF02037.27 EGG13967.1 - 2.4e-08 33.5 1.5 2.4e-08 33.5 1.5 1.8 2 0 0 2 2 2 1 SAP domain RNA_pol_3_Rpc31 PF11705.8 EGG13967.1 - 0.025 14.8 11.2 0.025 14.8 11.2 3.3 2 1 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 EGG13967.1 - 0.13 11.6 42.1 0.24 10.7 42.1 1.4 1 0 0 1 1 1 0 BUD22 Menin PF05053.13 EGG13967.1 - 8.8 4.6 17.2 12 4.2 17.2 1.1 1 0 0 1 1 1 0 Menin DUF1674 PF07896.12 EGG13968.1 - 2.8e-17 62.9 6.1 4.4e-17 62.3 6.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Ntox37 PF15535.6 EGG13968.1 - 0.077 13.4 1.4 0.077 13.4 1.4 1.5 1 1 0 1 1 1 0 Bacterial toxin 37 AAA_16 PF13191.6 EGG13969.1 - 5.8e-06 26.8 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG13969.1 - 0.001 19.3 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG13969.1 - 0.006 16.9 0.0 0.044 14.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGG13969.1 - 0.08 12.2 0.0 0.26 10.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Sec7 PF01369.20 EGG13970.1 - 3.5e-53 180.0 0.7 1e-52 178.5 0.7 1.8 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EGG13970.1 - 4.5e-11 43.2 3.6 3.2e-07 30.8 0.3 3.2 3 0 0 3 3 3 2 PH domain p31comet PF06581.12 EGG13971.1 - 1.2e-09 37.8 0.0 2.1e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Mad1 and Cdc20-bound-Mad2 binding Ferlin_C PF16165.5 EGG13971.1 - 2.3 8.2 5.7 0.56 10.1 0.2 2.6 2 1 1 3 3 3 0 Ferlin C-terminus Dicty_CAR PF05462.11 EGG13973.1 - 2.1e-07 30.4 2.7 5e-07 29.2 2.7 1.7 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 EGG13973.1 - 3e-06 26.7 2.6 3e-06 26.7 2.6 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 EGG13973.1 - 0.002 17.2 5.9 0.002 17.2 5.9 2.0 1 1 1 2 2 2 1 Frizzled/Smoothened family membrane region Importin_rep_3 PF18806.1 EGG13973.1 - 0.0065 16.5 0.0 0.021 14.9 0.0 2.0 1 1 0 1 1 1 1 Importin 13 repeat Trans_reg_C PF00486.28 EGG13974.1 - 0.015 15.4 0.3 4.6 7.4 0.1 2.8 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal HEPN_RiboL-PSP PF18735.1 EGG13975.1 - 0.027 14.4 0.1 0.033 14.1 0.1 1.1 1 0 0 1 1 1 0 RiboL-PSP-HEPN DUF676 PF05057.14 EGG13976.1 - 8.4e-44 149.7 2.8 9.2e-44 149.6 0.2 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGG13976.1 - 9.7e-08 32.1 0.6 1.7e-07 31.3 0.4 1.6 1 1 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGG13976.1 - 3.2e-06 27.0 0.1 6e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 EGG13976.1 - 5.6e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF900 PF05990.12 EGG13976.1 - 0.00075 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 EGG13976.1 - 0.00088 18.5 0.7 0.0022 17.2 0.0 1.9 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 EGG13976.1 - 0.0046 16.2 0.0 0.0087 15.4 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_2 PF01674.18 EGG13976.1 - 0.014 15.0 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_6 PF12697.7 EGG13976.1 - 0.21 12.2 0.0 0.53 10.8 0.0 1.4 1 1 1 2 2 2 0 Alpha/beta hydrolase family ALG11_N PF15924.5 EGG13977.1 - 2.5e-85 285.8 1.0 4.3e-85 285.0 1.0 1.4 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EGG13977.1 - 2e-26 92.6 0.0 3.3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGG13977.1 - 2.9e-13 50.4 0.0 5.7e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ras PF00071.22 EGG13978.1 - 6.1e-41 139.7 0.0 7.7e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG13978.1 - 4.7e-25 88.1 0.1 7.9e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG13978.1 - 8.6e-13 48.1 0.1 1.1e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG13978.1 - 9.5e-06 25.1 0.0 1.4e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG13978.1 - 7.3e-05 22.8 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 EGG13978.1 - 0.001 18.6 0.0 0.0026 17.3 0.1 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_15 PF13175.6 EGG13978.1 - 0.0011 18.7 2.9 0.0017 18.2 2.9 1.2 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 EGG13978.1 - 0.0026 17.3 0.0 0.98 8.9 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Pox_A14 PF05767.12 EGG13978.1 - 0.04 14.1 0.0 0.42 10.8 0.0 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 AAA_24 PF13479.6 EGG13978.1 - 0.04 13.6 0.6 0.069 12.9 0.2 1.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGG13978.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGG13978.1 - 0.051 13.5 0.3 0.16 11.9 0.0 1.9 2 1 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EGG13978.1 - 0.082 13.4 0.0 0.23 12.0 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EGG13978.1 - 0.087 13.2 0.0 0.15 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGG13978.1 - 0.13 12.2 0.0 0.97 9.3 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 EGG13978.1 - 0.14 12.7 4.8 0.38 11.2 4.8 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGG13978.1 - 0.16 11.7 0.0 0.48 10.2 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 EGG13978.1 - 0.17 12.3 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PDCD2_C PF04194.13 EGG13980.1 - 2.3e-35 122.2 6.9 2.3e-35 122.2 6.9 3.7 3 1 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain ydhR PF08803.11 EGG13980.1 - 0.024 14.5 0.1 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR LCCL PF03815.19 EGG13980.1 - 0.043 13.9 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 LCCL domain CDC45 PF02724.14 EGG13980.1 - 1.8 6.8 19.6 3.3 5.9 19.6 1.4 1 0 0 1 1 1 0 CDC45-like protein GST_N_4 PF17172.4 EGG13981.1 - 1.5e-19 70.6 0.1 3.3e-19 69.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EGG13981.1 - 1.1e-16 60.4 0.0 2.3e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EGG13981.1 - 5e-06 26.8 1.1 1e-05 25.9 0.2 1.9 3 0 0 3 3 3 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 EGG13981.1 - 9.7e-06 25.5 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG13981.1 - 0.00028 21.0 0.0 0.00066 19.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGG13981.1 - 0.0019 18.6 0.0 0.012 16.0 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG13981.1 - 0.024 14.9 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGG13981.1 - 0.066 13.5 0.1 0.29 11.4 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain RNase_PH PF01138.21 EGG13982.1 - 1e-35 123.1 0.1 1.5e-35 122.6 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGG13982.1 - 4.8e-06 26.5 0.0 0.00033 20.6 0.1 3.1 2 1 0 2 2 2 1 3' exoribonuclease family, domain 2 HSR PF03172.13 EGG13982.1 - 0.037 14.2 1.2 1.3 9.2 0.1 2.2 2 0 0 2 2 2 0 HSR domain Skp1_POZ PF03931.15 EGG13983.1 - 1.2e-06 28.6 0.3 0.0086 16.2 0.0 2.8 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Skp1 PF01466.19 EGG13983.1 - 0.00012 22.1 0.0 0.00032 20.8 0.0 1.8 1 0 0 1 1 1 1 Skp1 family, dimerisation domain SOG2 PF10428.9 EGG13983.1 - 4.3 6.4 42.1 0.22 10.7 35.0 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein XRN_N PF03159.18 EGG13984.1 - 6.6e-83 277.9 0.0 6.6e-83 277.9 0.0 2.8 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EGG13984.1 - 3.8e-77 260.1 8.2 2.8e-58 197.9 1.2 4.6 4 1 1 5 5 5 2 Xrn1 helical domain XRN1_D1 PF18332.1 EGG13984.1 - 2.1e-24 86.3 0.0 2.1e-24 86.3 0.0 2.7 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 EGG13984.1 - 9.3e-21 73.7 0.0 3.2e-20 72.0 0.1 1.9 2 0 0 2 2 2 1 Xrn1 SH3-like domain MFS_1 PF07690.16 EGG13984.1 - 6e-07 28.7 0.3 1.1e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily XRN1_D2_D3 PF18334.1 EGG13984.1 - 0.0057 16.8 0.4 0.063 13.5 0.0 3.0 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D2/D3 domain DUF5126 PF17166.4 EGG13984.1 - 0.058 13.3 3.6 0.52 10.2 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5126) UNC-93 PF05978.16 EGG13985.1 - 2e-16 60.1 11.5 4.5e-16 58.9 10.2 2.1 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EGG13985.1 - 2.3e-15 56.4 10.2 3.1e-15 56.0 10.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG13985.1 - 6.9e-07 28.5 10.5 1e-06 27.9 10.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGG13985.1 - 0.00037 19.5 5.9 0.00037 19.5 5.9 2.0 1 1 1 2 2 2 1 MFS_1 like family FNIP PF05725.12 EGG13986.1 - 2e-30 104.7 17.6 2.1e-12 47.0 0.3 6.3 3 2 1 6 6 6 5 FNIP Repeat Sigma54_AID PF00309.20 EGG13987.1 - 2.1 8.2 5.5 0.67 9.9 0.2 2.7 2 1 1 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) HECT PF00632.25 EGG13988.1 - 7.9e-72 242.3 0.9 1.9e-71 241.1 0.9 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.19 EGG13988.1 - 6.3e-07 30.2 4.0 2.3e-05 25.2 0.1 3.4 3 0 0 3 3 3 1 Filamin/ABP280 repeat Big_1 PF02369.16 EGG13988.1 - 0.034 14.1 2.3 8.8 6.4 0.0 3.8 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) DUF4728 PF15860.5 EGG13988.1 - 5.6 7.7 6.7 0.51 11.1 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) ETC_C1_NDUFA5 PF04716.14 EGG13989.1 - 6.4e-26 90.0 0.1 9.1e-26 89.5 0.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region ALS_ss_C PF10369.9 EGG13989.1 - 0.006 16.8 0.3 0.0087 16.2 0.3 1.2 1 0 0 1 1 1 1 Small subunit of acetolactate synthase Complex1_LYR PF05347.15 EGG13989.1 - 0.033 14.2 0.5 0.18 11.9 0.5 1.9 1 1 0 1 1 1 0 Complex 1 protein (LYR family) Cofilin_ADF PF00241.20 EGG13990.1 - 4.5e-12 45.8 0.8 5.9e-08 32.5 0.0 3.3 3 0 0 3 3 3 2 Cofilin/tropomyosin-type actin-binding protein BBS2_Mid PF14783.6 EGG13990.1 - 0.07 13.2 0.3 0.7 10.0 0.0 2.5 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region STE3 PF02076.15 EGG13991.1 - 0.042 13.0 6.9 0.47 9.6 6.9 2.1 1 1 0 1 1 1 0 Pheromone A receptor 7tm_1 PF00001.21 EGG13991.1 - 0.043 13.1 4.0 0.069 12.5 4.0 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) CcmH PF03918.14 EGG13991.1 - 0.099 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF4181 PF13789.6 EGG13991.1 - 0.27 11.5 4.2 0.15 12.3 1.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) PAP2 PF01569.21 EGG13992.1 - 6.9e-20 71.2 5.9 2e-19 69.7 5.9 1.8 1 0 0 1 1 1 1 PAP2 superfamily TatC PF00902.18 EGG13992.1 - 0.026 14.4 1.7 0.026 14.4 1.7 2.9 3 0 0 3 3 3 0 Sec-independent protein translocase protein (TatC) Rep_N PF08724.10 EGG13992.1 - 0.082 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Rep protein catalytic domain like Latrotoxin_C PF15658.6 EGG13992.1 - 0.1 12.4 0.3 0.19 11.5 0.3 1.4 1 0 0 1 1 1 0 Latrotoxin C-terminal domain Gly-zipper_Omp PF13488.6 EGG13992.1 - 0.19 11.8 2.6 7.9 6.6 0.1 2.9 3 0 0 3 3 3 0 Glycine zipper Kelch_6 PF13964.6 EGG13994.1 - 9.1e-38 127.3 3.4 3.4e-07 30.3 0.0 6.2 4 2 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EGG13994.1 - 1.3e-32 111.2 1.4 7.7e-07 28.6 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EGG13994.1 - 5.6e-32 109.5 5.6 3.1e-07 30.3 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG13994.1 - 2e-25 88.3 6.3 2e-05 24.4 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGG13994.1 - 9e-25 85.7 10.2 7.7e-05 22.5 0.3 6.3 5 1 1 6 6 6 4 Kelch motif Kelch_3 PF13415.6 EGG13994.1 - 4.1e-24 84.3 3.4 8.6e-06 25.9 0.1 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain F-box-like PF12937.7 EGG13994.1 - 2.2e-06 27.4 0.1 1.3e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGG13994.1 - 0.00038 20.3 0.0 0.00083 19.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGG13994.1 - 0.0007 19.5 0.1 0.0027 17.6 0.0 1.9 2 0 0 2 2 2 1 F-box Cryptochrome_C PF12546.8 EGG13994.1 - 0.067 13.8 0.2 0.12 13.0 0.2 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal PRANC PF09372.10 EGG13994.1 - 0.11 12.8 6.3 0.3 11.4 6.3 1.7 1 0 0 1 1 1 0 PRANC domain Topoisom_I_N PF02919.15 EGG13995.1 - 1.1e-87 293.1 3.9 1.1e-87 293.1 3.9 3.4 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EGG13995.1 - 3.5e-32 110.1 0.9 1.1e-31 108.5 0.9 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain Topoisom_I PF01028.20 EGG13995.1 - 1.1e-27 96.8 0.1 1.1e-27 96.8 0.1 2.9 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core EGF_2 PF07974.13 EGG13997.1 - 4.4 7.8 11.8 10 6.6 11.8 1.7 1 0 0 1 1 1 0 EGF-like domain Metallothio_5 PF02067.15 EGG13997.1 - 4.5 7.5 8.7 9 6.5 8.7 1.5 1 0 0 1 1 1 0 Metallothionein family 5 14-3-3 PF00244.20 EGG14001.1 - 2.6e-105 350.8 6.4 2.6e-105 350.8 6.4 1.8 2 0 0 2 2 2 1 14-3-3 protein zf-CHY PF05495.12 EGG14001.1 - 1.9e-09 37.9 16.0 1.9e-09 37.9 16.0 2.4 2 1 1 3 3 3 1 CHY zinc finger Zn-ribbon_8 PF09723.10 EGG14001.1 - 0.002 18.2 2.1 0.002 18.2 2.1 2.7 2 0 0 2 2 2 1 Zinc ribbon domain RNA_POL_M_15KD PF02150.16 EGG14001.1 - 0.013 15.4 13.5 0.77 9.7 1.8 4.3 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit Ank_2 PF12796.7 EGG14002.1 - 5.1e-05 23.8 12.0 2.6 8.7 0.1 7.3 3 3 5 9 9 9 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG14002.1 - 0.21 12.2 2.0 5.9e+02 1.7 0.0 6.7 7 1 1 8 8 8 0 Ankyrin repeat Rho_N PF07498.12 EGG14003.1 - 0.012 15.6 1.1 0.077 12.9 0.2 2.7 3 0 0 3 3 3 0 Rho termination factor, N-terminal domain DEK_C PF08766.11 EGG14003.1 - 0.2 11.6 5.4 2 8.4 0.1 4.4 4 0 0 4 4 4 0 DEK C terminal domain GPR15L PF15854.5 EGG14004.1 - 0.032 14.4 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 RRM_1 PF00076.22 EGG14006.1 - 9.3e-10 38.2 0.0 1.8e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 EGG14006.1 - 8.8e-06 26.0 0.0 2.2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 PWI domain DUF3915 PF13054.6 EGG14006.1 - 0.0067 16.4 0.2 0.0067 16.4 0.2 4.7 3 1 1 4 4 4 1 Protein of unknown function (DUF3915) p450 PF00067.22 EGG14007.1 - 1e-56 192.7 0.1 1.3e-56 192.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 VKOR PF07884.14 EGG14007.1 - 0.085 13.0 0.3 0.16 12.1 0.3 1.5 1 0 0 1 1 1 0 Vitamin K epoxide reductase family DUF2749 PF10907.8 EGG14007.1 - 0.19 11.9 1.9 0.39 10.9 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) SUIM_assoc PF16619.5 EGG14008.1 - 0.00035 20.6 0.3 0.00035 20.6 0.3 2.2 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 EGG14008.1 - 0.046 12.7 2.8 0.056 12.4 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FNIP PF05725.12 EGG14008.1 - 6.6 7.0 16.2 10 6.3 0.2 5.8 4 2 3 7 7 7 0 FNIP Repeat Csm1_B PF18211.1 EGG14010.1 - 0.051 13.4 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Csm1 subunit domain B Actin PF00022.19 EGG14011.1 - 1.9e-152 507.6 0.0 6e-152 506.0 0.0 1.6 1 1 0 1 1 1 1 Actin Spt20 PF12090.8 EGG14012.1 - 0.69 9.5 22.0 1.4 8.5 22.0 1.5 1 0 0 1 1 1 0 Spt20 family dNK PF01712.19 EGG14013.1 - 0.0019 18.1 0.1 0.0022 17.9 0.1 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase Chal_sti_synt_C PF02797.15 EGG14014.1 - 7.6e-22 77.9 0.0 1.2e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 EGG14014.1 - 9.4e-17 61.2 0.1 1.4e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 EGG14014.1 - 6e-16 58.6 0.4 8.2e-16 58.1 0.4 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 EGG14014.1 - 2.8e-08 33.8 0.0 1.2e-06 28.6 0.0 3.1 3 1 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EGG14014.1 - 1.5e-06 27.9 0.1 3.8e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Raco_middle PF17651.1 EGG14014.1 - 0.039 13.6 0.0 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 RACo middle region SMC_ScpB PF04079.16 EGG14014.1 - 0.041 13.5 0.0 5.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB DUF3963 PF13124.6 EGG14014.1 - 0.19 11.7 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) DAO PF01266.24 EGG14015.1 - 0.0006 19.5 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGG14015.1 - 0.0042 16.0 5.3 0.0043 16.0 0.3 2.9 2 1 0 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.12 EGG14015.1 - 0.0087 15.1 0.0 0.028 13.5 0.0 1.9 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EGG14015.1 - 0.011 15.0 0.0 4 6.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 EGG14015.1 - 0.015 14.5 0.1 0.2 10.9 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 EGG14015.1 - 0.032 13.4 0.0 0.071 12.3 0.0 1.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG14015.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Endonuc_subdom PF09062.10 EGG14015.1 - 0.076 13.8 2.5 3.7 8.4 0.0 3.6 3 1 0 3 3 3 0 PI-PfuI Endonuclease subdomain NAD_binding_8 PF13450.6 EGG14015.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain RNA_pol_I_A49 PF06870.12 EGG14016.1 - 9.3e-36 123.5 4.4 1.3e-35 123.1 4.4 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Cyt-b5 PF00173.28 EGG14017.1 - 9.6e-20 70.5 0.2 1.2e-19 70.2 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_C26 PF07722.13 EGG14019.1 - 1.9e-20 73.6 0.0 4.1e-20 72.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 EGG14019.1 - 2.6e-09 37.1 0.0 4.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I RNase_Zc3h12a_2 PF14626.6 EGG14019.1 - 0.14 12.3 0.0 0.49 10.6 0.0 1.9 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Peptidase_M8 PF01457.16 EGG14020.1 - 1.9e-17 63.2 0.0 2.7e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin TIG PF01833.24 EGG14020.1 - 7.2e-05 22.8 0.2 7.2e-05 22.8 0.2 2.8 2 1 0 2 2 2 1 IPT/TIG domain Tom22 PF04281.13 EGG14020.1 - 0.051 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF3947 PF13135.6 EGG14020.1 - 0.5 10.6 4.2 1.2 9.4 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) PLDc_2 PF13091.6 EGG14021.1 - 1.7e-08 34.4 0.0 6.2e-05 22.9 0.0 3.6 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 EGG14021.1 - 1.8e-07 31.1 0.2 0.0034 17.5 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Suf PF05843.14 EGG14021.1 - 3.8 7.4 11.3 0.12 12.4 3.4 2.5 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Secretin_N_2 PF07655.13 EGG14021.1 - 3.9 8.1 26.1 4.8 7.8 0.1 3.5 3 0 0 3 3 3 0 Secretin N-terminal domain BRAP2 PF07576.12 EGG14022.1 - 1.4e-34 118.3 0.0 2.8e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EGG14022.1 - 2.2e-19 69.5 6.3 5.9e-19 68.2 6.3 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EGG14022.1 - 7.6e-09 35.8 8.9 7.6e-09 35.8 8.9 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG14022.1 - 4.9e-06 26.3 8.6 4.9e-06 26.3 8.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG14022.1 - 2.1e-05 24.4 1.5 2.1e-05 24.4 1.5 2.8 1 1 1 2 2 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGG14022.1 - 2.2e-05 24.6 7.2 2.2e-05 24.6 7.2 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EGG14022.1 - 0.00013 21.8 20.7 0.0054 16.6 8.0 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG14022.1 - 0.00062 19.7 7.8 0.00062 19.7 7.8 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGG14022.1 - 0.0009 19.1 7.1 0.0009 19.1 7.1 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGG14022.1 - 0.001 18.7 6.1 0.001 18.7 6.1 2.4 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_4 PF14570.6 EGG14022.1 - 0.0098 15.7 6.3 0.0098 15.7 6.3 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain CENP-F_leu_zip PF10473.9 EGG14022.1 - 0.018 15.1 10.9 0.018 15.1 10.9 2.3 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-UBP_var PF17807.1 EGG14022.1 - 0.02 14.6 0.9 0.051 13.3 0.9 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger zf-ANAPC11 PF12861.7 EGG14022.1 - 0.12 12.4 10.3 0.048 13.7 7.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHF5 PF03660.14 EGG14022.1 - 1.1 9.5 10.6 3.1 8.0 9.9 2.1 2 0 0 2 2 2 0 PHF5-like protein T6PP_N PF18572.1 EGG14022.1 - 1.6 8.6 11.4 0.62 9.9 7.8 2.1 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF3450 PF11932.8 EGG14022.1 - 8.5 5.6 14.0 1.9 7.7 10.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) 4HBT PF03061.22 EGG14023.1 - 3.7e-08 33.6 0.1 0.00039 20.7 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily RRM_1 PF00076.22 EGG14023.1 - 3.1e-05 23.7 0.1 0.00012 21.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEPcase PF00311.17 EGG14024.1 - 5.7e-277 921.0 0.0 7.1e-277 920.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 EGG14024.1 - 0.0026 16.3 0.0 0.011 14.2 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxylase FRB_dom PF08771.11 EGG14024.1 - 0.048 14.1 0.5 0.37 11.2 0.0 2.7 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain Ndc80_HEC PF03801.13 EGG14025.1 - 1.7e-37 128.4 0.0 1.7e-37 128.4 0.0 3.5 3 1 0 3 3 3 1 HEC/Ndc80p family Zip PF02535.22 EGG14025.1 - 6.9 5.8 5.5 17 4.5 5.5 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter EGF_2 PF07974.13 EGG14026.1 - 0.011 16.1 13.4 0.028 14.8 13.4 1.8 1 0 0 1 1 1 0 EGF-like domain RE_MamI PF09567.10 EGG14026.1 - 0.029 14.0 0.8 0.065 12.9 0.8 1.5 1 0 0 1 1 1 0 MamI restriction endonuclease PIF6 PF05341.11 EGG14026.1 - 0.17 12.1 2.2 0.99 9.6 0.0 3.2 3 0 0 3 3 3 0 Per os infectivity factor 6 LPP20 PF02169.16 EGG14027.1 - 0.19 12.1 3.1 0.49 10.8 3.1 1.8 1 0 0 1 1 1 0 LPP20 lipoprotein Zn-ribbon_8 PF09723.10 EGG14027.1 - 0.95 9.6 9.1 1.4e+02 2.7 7.4 3.3 2 1 0 2 2 2 0 Zinc ribbon domain Orthopox_F6 PF06601.12 EGG14028.1 - 0.01 16.0 0.4 0.021 15.0 0.4 1.5 1 0 0 1 1 1 0 Orthopoxvirus F6 protein Exonuc_VII_L PF02601.15 EGG14028.1 - 0.019 14.6 7.9 0.022 14.3 7.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4971 PF16341.5 EGG14028.1 - 0.054 13.3 0.3 0.63 9.9 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4971) CHD5 PF04420.14 EGG14028.1 - 0.53 10.1 0.1 0.53 10.1 0.1 2.3 2 1 0 2 2 2 0 CHD5-like protein Mt_ATP-synt_D PF05873.12 EGG14028.1 - 0.64 9.9 11.0 0.16 11.8 7.1 1.9 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) SH3_2 PF07653.17 EGG14029.1 - 1.4e-11 43.9 0.1 2.1e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGG14029.1 - 4.7e-08 32.8 0.1 4.7e-08 32.8 0.1 1.6 2 0 0 2 2 2 1 Variant SH3 domain tRNA-synt_1c PF00749.21 EGG14030.1 - 1.8e-96 322.7 0.1 2.7e-96 322.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGG14030.1 - 1.1e-28 100.3 0.3 2.3e-28 99.2 0.3 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 EGG14030.1 - 1.4e-05 25.2 0.0 3.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG14030.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG14030.1 - 0.0025 18.0 0.1 0.0078 16.4 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CBF PF03914.17 EGG14031.1 - 3e-32 112.0 3.3 2.4e-31 109.1 0.2 3.1 4 0 0 4 4 4 2 CBF/Mak21 family NFACT-R_1 PF05670.13 EGG14032.1 - 8.5e-46 155.1 1.8 1.9e-45 154.0 0.1 2.0 2 0 0 2 2 2 1 NFACT protein RNA binding domain MCU PF04678.13 EGG14032.1 - 7.3 6.7 9.2 6.5 6.8 8.2 1.4 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Beach PF02138.18 EGG14033.1 - 4.1e-41 141.2 0.1 1.1e-40 139.7 0.1 1.7 1 0 0 1 1 1 1 Beige/BEACH domain Pkinase PF00069.25 EGG14033.1 - 1.6e-14 54.0 0.1 7.1e-09 35.4 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain WD40 PF00400.32 EGG14033.1 - 8.7e-10 39.1 9.4 0.00058 20.6 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Kinase-like PF14531.6 EGG14033.1 - 0.00018 21.0 0.1 0.00037 19.9 0.1 1.4 1 0 0 1 1 1 1 Kinase-like ANAPC4_WD40 PF12894.7 EGG14033.1 - 0.00052 20.3 0.0 2.5 8.4 0.0 4.2 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nop PF01798.18 EGG14034.1 - 8.1e-82 274.1 0.5 8.1e-82 274.1 0.5 2.7 2 1 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGG14034.1 - 9.2e-20 70.8 3.0 9.2e-20 70.8 3.0 3.7 2 1 0 2 2 2 1 NOP5NT (NUC127) domain Calcipressin PF04847.12 EGG14035.1 - 0.039 13.7 0.2 0.046 13.5 0.2 1.0 1 0 0 1 1 1 0 Calcipressin Kelch_1 PF01344.25 EGG14036.1 - 3.2e-35 119.4 9.1 3.7e-09 36.0 0.1 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EGG14036.1 - 6.4e-34 115.4 10.5 7.8e-08 32.1 0.1 7.3 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 EGG14036.1 - 2.5e-29 100.6 11.6 1.7e-08 34.4 0.0 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EGG14036.1 - 6.3e-28 96.5 21.5 1.9e-08 34.1 0.1 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EGG14036.1 - 4.7e-25 86.6 11.0 1e-05 25.3 0.0 6.9 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 EGG14036.1 - 8.1e-23 80.2 6.5 1.4e-07 31.7 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain F-box-like PF12937.7 EGG14036.1 - 1e-06 28.5 0.0 2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG14036.1 - 3.5e-06 26.7 0.1 6.9e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain Pro_isomerase PF00160.21 EGG14037.1 - 1.6e-47 161.7 0.1 4.1e-47 160.4 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EGG14037.1 - 1.3e-05 25.8 1.6 0.00094 20.0 0.4 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG14037.1 - 0.0013 19.0 0.0 1.6 9.1 0.0 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain MMU163 PF17119.5 EGG14037.1 - 7.8 5.6 8.2 18 4.4 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Aminotran_1_2 PF00155.21 EGG14038.1 - 8e-95 318.1 0.0 9.1e-95 317.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Myb_DNA-bind_6 PF13921.6 EGG14038.1 - 0.072 13.3 0.0 3.6 7.9 0.0 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain CARDB PF07705.11 EGG14039.1 - 0.045 14.0 0.7 0.088 13.1 0.7 1.4 1 0 0 1 1 1 0 CARDB zf-UBR PF02207.20 EGG14040.1 - 7e-17 61.4 12.0 7e-17 61.4 12.0 3.4 5 0 0 5 5 5 1 Putative zinc finger in N-recognin (UBR box) SH3_13 PF18335.1 EGG14040.1 - 0.002 17.9 2.4 0.01 15.6 2.4 2.2 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain zf-RING_5 PF14634.6 EGG14040.1 - 0.0052 16.7 0.5 0.0052 16.7 0.5 3.4 3 0 0 3 3 3 1 zinc-RING finger domain SPX PF03105.19 EGG14040.1 - 9.7 6.0 24.7 3.9 7.3 10.6 3.4 3 1 0 3 3 3 0 SPX domain EGF_2 PF07974.13 EGG14041.1 - 0.11 12.9 10.4 0.17 12.3 10.4 1.4 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EGG14041.1 - 0.38 10.9 3.5 0.77 9.9 3.5 1.6 1 0 0 1 1 1 0 Tenascin EGF domain TMEM154 PF15102.6 EGG14041.1 - 1.2 9.0 9.9 3.7 7.5 9.9 1.9 1 0 0 1 1 1 0 TMEM154 protein family Ig_mannosidase PF17753.1 EGG14042.1 - 0.005 16.6 0.1 0.011 15.4 0.1 1.6 1 0 0 1 1 1 1 Ig-fold domain MULE PF10551.9 EGG14042.1 - 0.1 13.0 0.0 8.9 6.8 0.0 2.9 2 0 0 2 2 2 0 MULE transposase domain Thioredoxin_11 PF18078.1 EGG14042.1 - 0.11 12.6 0.9 5.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin-like SNTX domain SfsA_N PF17746.1 EGG14042.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 SfsA N-terminal OB domain Sec23_trunk PF04811.15 EGG14044.1 - 2.4e-22 79.7 0.0 4e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGG14044.1 - 1.1e-13 50.8 0.0 2.8e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EGG14044.1 - 5.1e-12 45.6 1.6 1.5e-11 44.2 1.6 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EGG14044.1 - 2.7e-05 24.8 0.2 0.00019 22.1 0.1 2.5 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Vps36-NZF-N PF16988.5 EGG14044.1 - 2.3 7.7 6.3 0.35 10.3 0.3 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_jaz PF12171.8 EGG14045.1 - 2.1e-09 37.4 0.2 3.3e-09 36.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGG14045.1 - 0.021 15.1 0.4 0.049 14.0 0.1 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Glyco_transf_22 PF03901.17 EGG14046.1 - 6.2e-79 266.2 35.1 8.4e-79 265.7 35.1 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3825 PF12873.7 EGG14046.1 - 0.074 12.5 0.0 6.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3825) Methyltransf_16 PF10294.9 EGG14047.1 - 1.5e-10 41.1 0.0 2.6e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase RNR_N PF08343.10 EGG14048.1 - 0.083 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal GATA PF00320.27 EGG14049.1 - 2.2e-15 56.0 4.9 4.7e-15 54.9 4.9 1.6 1 0 0 1 1 1 1 GATA zinc finger Ank_2 PF12796.7 EGG14049.1 - 4.8e-05 23.9 0.0 0.012 16.1 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14049.1 - 0.0063 17.1 0.2 0.24 12.1 0.0 3.5 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG14049.1 - 0.13 12.7 0.0 0.59 10.5 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) CBFD_NFYB_HMF PF00808.23 EGG14050.1 - 4.1e-18 65.4 0.3 7e-18 64.7 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGG14050.1 - 0.038 14.4 0.0 0.038 14.4 0.0 2.3 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF5427 PF10310.9 EGG14050.1 - 0.077 11.9 5.0 0.088 11.8 5.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) TipAS PF07739.13 EGG14050.1 - 0.5 10.9 3.5 0.89 10.1 3.5 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain FAA_hydrolase PF01557.18 EGG14051.1 - 1.5e-57 194.8 0.0 2.4e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EGG14051.1 - 4.4e-31 107.2 0.0 2.8e-30 104.7 0.0 2.3 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal COMM_domain PF07258.14 EGG14051.1 - 2e-13 50.3 1.2 6.2e-13 48.7 1.2 1.9 1 0 0 1 1 1 1 COMM domain Mucin PF01456.17 EGG14051.1 - 0.015 15.3 10.3 0.03 14.3 10.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 EGG14051.1 - 0.049 11.8 15.1 0.019 13.2 10.0 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 tRNA-synt_1 PF00133.22 EGG14052.1 - 1.6e-185 617.8 0.1 3.5e-184 613.4 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGG14052.1 - 3.8e-31 108.1 0.1 8.4e-31 107.0 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGG14052.1 - 8.3e-18 64.3 2.5 4.6e-10 38.8 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGG14052.1 - 9.7e-08 31.7 0.1 8.2e-05 22.2 0.0 2.8 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EGG14052.1 - 0.00069 19.1 0.0 0.57 9.5 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 EGG14052.1 - 0.004 17.4 3.5 0.004 17.4 3.5 1.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.19 EGG14052.1 - 0.0076 15.2 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (R) Phage-A118_gp45 PF10653.9 EGG14052.1 - 0.017 15.1 0.1 0.1 12.6 0.0 2.3 2 0 0 2 2 2 0 Protein gp45 of Bacteriophage A118 ABC_tran_CTD PF16326.5 EGG14052.1 - 1.7 9.0 8.1 2.1 8.7 4.0 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain TFIID-31kDa PF02291.15 EGG14053.1 - 1.8e-46 157.2 0.1 2.9e-46 156.5 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGG14053.1 - 3.1e-06 27.1 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 EGG14053.1 - 0.0001 22.6 0.1 0.00021 21.6 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGG14053.1 - 0.0043 17.2 0.1 0.0083 16.2 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EGG14053.1 - 0.011 16.1 9.3 0.12 12.7 9.3 2.4 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID_30kDa PF03540.13 EGG14053.1 - 0.011 15.7 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit LAP1C PF05609.12 EGG14053.1 - 2.1 7.3 14.5 2.8 7.0 14.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Spc7_N PF15402.6 EGG14053.1 - 2.5 6.2 17.4 3.3 5.9 17.4 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Presenilin PF01080.17 EGG14053.1 - 6.6 5.4 11.7 8.2 5.1 11.7 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EGG14053.1 - 9.3 5.4 8.5 16 4.6 8.5 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Ago_N_1 PF18351.1 EGG14054.1 - 0.04 14.3 0.5 0.075 13.5 0.5 1.4 1 0 0 1 1 1 0 Fungal Argonaute N-terminal domain LRR_6 PF13516.6 EGG14054.1 - 0.091 12.9 0.8 0.24 11.5 0.8 1.7 1 0 0 1 1 1 0 Leucine Rich repeat 7TM_GPCR_Sru PF10322.9 EGG14054.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru UCR_Fe-S_N PF10399.9 EGG14054.1 - 1.1 8.7 2.2 1.7 8.1 2.2 1.3 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Methyltransf_2 PF00891.18 EGG14056.1 - 2.9e-16 59.4 0.0 4.5e-15 55.5 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 EGG14056.1 - 0.0038 16.8 0.0 0.029 13.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EGG14056.1 - 0.012 15.6 7.6 0.091 12.7 0.0 3.3 3 0 0 3 3 3 0 Methyltransferase domain DUF5523 PF17661.1 EGG14056.1 - 0.014 15.1 0.5 0.014 15.1 0.5 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5523) SUIM_assoc PF16619.5 EGG14056.1 - 0.14 12.2 11.1 0.19 11.8 4.4 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Gti1_Pac2 PF09729.9 EGG14056.1 - 7.3 6.6 9.4 6 6.9 4.8 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family NUDIX PF00293.28 EGG14059.1 - 5.7e-22 78.2 0.0 7e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EGG14059.1 - 0.011 15.7 0.0 0.031 14.2 0.0 1.7 1 1 0 1 1 1 0 NUDIX domain NTP_transferase PF00483.23 EGG14061.1 - 4.9e-09 36.1 0.0 1.2e-08 34.9 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 EGG14061.1 - 4.5e-05 23.0 10.5 0.11 12.3 3.3 3.8 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EGG14061.1 - 0.00038 18.8 0.8 0.00071 17.8 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 EGG14061.1 - 0.013 15.9 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EGG14061.1 - 0.034 13.9 7.9 2.7 7.8 0.0 3.5 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase EMC1_C PF07774.13 EGG14062.1 - 4.2e-54 183.5 1.9 6.7e-54 182.8 1.9 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EGG14062.1 - 3.9e-08 33.2 5.0 5e-07 29.6 0.4 3.8 3 2 1 4 4 4 1 PQQ-like domain PQQ PF01011.21 EGG14062.1 - 0.097 12.6 4.5 13 6.0 0.0 5.4 8 0 0 8 8 8 0 PQQ enzyme repeat Ribosomal_L30 PF00327.20 EGG14062.1 - 0.15 12.0 0.2 0.75 9.7 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e DsbG_N PF18257.1 EGG14062.1 - 0.43 10.8 3.4 3 8.0 0.1 3.2 3 0 0 3 3 3 0 Disulfide isomerase DsbG N-terminal DUF727 PF05303.12 EGG14063.1 - 1.3e-26 92.7 0.0 1.5e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF727) SIR2_2 PF13289.6 EGG14064.1 - 3.1e-24 85.7 0.5 1.5e-23 83.5 0.0 2.5 3 0 0 3 3 3 1 SIR2-like domain E1_DerP2_DerF2 PF02221.15 EGG14065.1 - 6.2e-23 81.7 0.2 7.4e-23 81.5 0.2 1.0 1 0 0 1 1 1 1 ML domain He_PIG PF05345.12 EGG14065.1 - 0.68 10.2 4.4 1.4 9.2 1.7 2.4 2 1 1 3 3 3 0 Putative Ig domain Gp5_C PF06715.12 EGG14065.1 - 3.6 7.9 4.9 0.72 10.1 0.4 2.3 3 0 0 3 3 3 0 Gp5 C-terminal repeat (3 copies) Peptidase_M24 PF00557.24 EGG14066.1 - 2.3e-55 187.5 0.6 3.3e-55 187.0 0.6 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGG14066.1 - 4.2e-21 75.0 0.0 1e-20 73.7 0.0 1.6 1 1 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF5590 PF17881.1 EGG14066.1 - 0.15 12.2 0.2 0.36 10.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) XRN_M PF17846.1 EGG14067.1 - 1.4e-112 376.9 4.6 1.4e-112 376.9 4.6 4.8 2 2 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 EGG14067.1 - 3.3e-95 318.1 0.0 3.3e-95 318.1 0.0 3.9 3 2 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus RTC_insert PF05189.13 EGG14067.1 - 0.13 12.7 0.1 0.5 10.9 0.1 1.9 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain Methyltrans_SAM PF10672.9 EGG14068.1 - 4.7e-15 55.5 0.0 8e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_31 PF13847.6 EGG14068.1 - 5.7e-06 26.2 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGG14068.1 - 0.00035 20.2 0.2 0.0015 18.2 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EGG14068.1 - 0.00096 19.8 0.0 0.0026 18.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EGG14068.1 - 0.015 14.9 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 EGG14068.1 - 0.023 15.3 0.0 0.085 13.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 EGG14068.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ig_mannosidase PF17753.1 EGG14069.1 - 5.4e-14 51.7 0.1 2.1e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 EGG14069.1 - 6.3e-06 26.2 0.4 0.001 19.0 0.1 2.7 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EGG14069.1 - 0.00014 22.5 0.2 0.00014 22.5 0.2 2.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 2 DUF5470 PF17564.2 EGG14069.1 - 0.43 10.8 2.2 1.2 9.3 2.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5470) LSM PF01423.22 EGG14070.1 - 5.7e-15 54.8 0.2 8.9e-15 54.1 0.2 1.3 1 0 0 1 1 1 1 LSM domain EB PF01683.18 EGG14071.1 - 0.022 15.0 39.7 0.69 10.2 10.7 4.4 2 1 2 4 4 4 0 EB module Dickkopf_N PF04706.12 EGG14071.1 - 2 8.9 39.5 0.44 11.1 4.8 4.8 5 1 0 5 5 5 0 Dickkopf N-terminal cysteine-rich region FGGY_N PF00370.21 EGG14072.1 - 7e-71 238.6 0.2 9.9e-71 238.2 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EGG14072.1 - 3.6e-29 101.9 0.0 6.3e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain YadA_anchor PF03895.15 EGG14072.1 - 0.078 13.1 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 YadA-like membrane anchor domain zf-C3Hc3H PF13891.6 EGG14073.1 - 1e-29 102.7 15.3 3.2e-16 59.4 2.0 2.4 2 0 0 2 2 2 2 Potential DNA-binding domain DUF5320 PF17253.2 EGG14073.1 - 0.035 15.2 1.1 0.035 15.2 1.1 3.5 5 0 0 5 5 5 0 Family of unknown function (DUF5320) PRR20 PF15708.5 EGG14073.1 - 1 9.2 5.9 2.5 8.0 5.9 1.6 1 0 0 1 1 1 0 Proline-rich protein family 20 zf-RING_2 PF13639.6 EGG14073.1 - 3.5 8.0 6.6 5.3 7.5 0.9 2.6 2 0 0 2 2 2 0 Ring finger domain VWA_3 PF13768.6 EGG14074.1 - 2.9e-29 102.0 0.0 6.5e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 EGG14074.1 - 2.6e-28 98.5 0.0 7.6e-28 96.9 0.0 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 EGG14074.1 - 1e-12 48.6 0.1 1e-11 45.4 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGG14074.1 - 2.3e-10 41.1 0.0 3e-09 37.5 0.0 2.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 EGG14074.1 - 0.00017 21.4 0.0 0.00041 20.2 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 EGG14074.1 - 0.046 13.1 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Mpv17_PMP22 PF04117.12 EGG14075.1 - 1.1e-19 70.4 0.4 6.7e-19 67.9 0.2 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family PetN PF03742.14 EGG14075.1 - 0.02 14.8 0.3 0.041 13.8 0.3 1.5 1 0 0 1 1 1 0 PetN DUF2818 PF10993.8 EGG14075.1 - 0.052 14.1 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2818) zf-C2H2_8 PF15909.5 EGG14076.1 - 0.11 12.8 0.2 0.26 11.6 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon DUF2185 PF09951.9 EGG14077.1 - 5.4e-29 99.9 0.1 9.5e-29 99.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2185) DUF2314 PF10077.9 EGG14077.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) CusF_Ec PF11604.8 EGG14077.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF Ras PF00071.22 EGG14078.1 - 2e-47 160.8 0.3 3.3e-47 160.1 0.3 1.4 1 0 0 1 1 1 1 Ras family HVSL PF09749.9 EGG14078.1 - 7e-36 123.9 0.1 1.3e-35 123.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein Roc PF08477.13 EGG14078.1 - 2.1e-27 95.7 0.1 5.7e-27 94.3 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG14078.1 - 2e-17 63.2 0.2 3.7e-17 62.3 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG14078.1 - 3e-06 26.8 0.3 7.4e-06 25.5 0.3 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG14078.1 - 0.00023 21.2 0.0 0.00074 19.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG14078.1 - 0.0018 17.8 2.2 0.0066 16.0 0.0 2.7 3 1 1 4 4 4 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 EGG14078.1 - 0.017 15.2 0.1 0.1 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain 2_5_RNA_ligase2 PF13563.6 EGG14078.1 - 0.039 13.9 0.0 0.097 12.6 0.0 1.7 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily AAA_24 PF13479.6 EGG14078.1 - 0.047 13.4 1.0 0.16 11.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain SRPRB PF09439.10 EGG14078.1 - 0.063 12.7 0.3 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 EGG14078.1 - 0.079 12.4 0.1 0.21 11.0 0.1 1.7 1 0 0 1 1 1 0 Bacterial TniB protein HP0268 PF18618.1 EGG14078.1 - 0.082 13.3 3.1 7.3 7.1 0.0 3.3 3 0 0 3 3 3 0 HP0268 AAA_22 PF13401.6 EGG14078.1 - 0.11 12.8 0.0 0.38 11.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain LigT_PEase PF02834.16 EGG14078.1 - 0.18 12.0 0.0 0.59 10.4 0.0 1.9 2 0 0 2 2 2 0 LigT like Phosphoesterase Carboxyl_trans PF01039.22 EGG14079.1 - 3.3e-151 504.3 0.0 4.9e-151 503.7 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain RhoGEF PF00621.20 EGG14079.1 - 1.1e-46 159.4 9.9 1.1e-46 159.4 9.9 2.9 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 EGG14079.1 - 2.5e-24 85.8 4.3 5.2e-13 49.4 0.6 3.6 3 0 0 3 3 3 2 PH domain ArfGap PF01412.18 EGG14079.1 - 6.3e-20 71.4 0.0 2.1e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CH PF00307.31 EGG14079.1 - 1.5e-17 63.7 1.9 3.5e-17 62.6 0.2 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain PH_11 PF15413.6 EGG14079.1 - 7.7e-06 26.3 0.9 0.00053 20.4 0.1 3.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 EGG14079.1 - 3.6e-05 24.1 0.4 0.00063 20.1 0.1 3.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 EGG14079.1 - 0.0018 18.1 2.2 2.2 8.1 0.5 4.2 3 1 0 3 3 3 1 Pleckstrin homology domain CAMSAP_CH PF11971.8 EGG14079.1 - 0.02 14.7 0.0 0.058 13.2 0.0 1.8 1 0 0 1 1 1 0 CAMSAP CH domain IQ PF00612.27 EGG14079.1 - 0.083 12.7 6.9 0.084 12.7 1.3 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif RTP1_C1 PF10363.9 EGG14080.1 - 4.7e-32 110.5 0.4 1.2e-30 106.0 0.0 3.4 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EGG14080.1 - 1.5e-09 37.3 0.0 4.6e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_EZ PF13513.6 EGG14080.1 - 0.0016 18.9 0.0 0.37 11.3 0.0 4.0 3 1 1 4 4 4 1 HEAT-like repeat HEAT PF02985.22 EGG14080.1 - 0.029 14.6 0.4 0.34 11.3 0.2 3.1 2 0 0 2 2 2 0 HEAT repeat Pkinase PF00069.25 EGG14081.1 - 1e-65 221.7 0.0 1.2e-64 218.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG14081.1 - 2.2e-28 99.2 4.3 1.6e-20 73.5 0.1 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG14081.1 - 1.8e-05 23.9 0.2 2.6e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGG14081.1 - 0.00024 21.1 1.0 0.089 12.7 0.6 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_C PF00433.24 EGG14081.1 - 0.00046 20.8 0.4 0.0011 19.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGG14081.1 - 0.0031 16.9 1.3 0.018 14.4 0.0 2.6 3 1 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.11 EGG14081.1 - 0.013 14.6 0.5 0.025 13.6 0.5 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 SBF2 PF12335.8 EGG14081.1 - 0.58 9.7 5.8 10 5.6 0.1 2.2 2 0 0 2 2 2 0 Myotubularin protein GTP_EFTU PF00009.27 EGG14082.1 - 7.3e-62 208.4 1.3 3.1e-61 206.3 1.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGG14082.1 - 5.4e-21 74.4 0.2 1.6e-20 72.9 0.2 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EGG14082.1 - 6.6e-20 71.0 0.0 2.5e-19 69.1 0.0 2.1 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EGG14082.1 - 1.7e-14 53.9 1.6 1e-13 51.4 0.4 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 EGG14082.1 - 2.1e-06 27.5 0.0 5.4e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV RF3_C PF16658.5 EGG14082.1 - 1.4e-05 24.9 0.0 3.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EGG14082.1 - 0.00011 22.2 0.0 0.0003 20.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Nodulin-like PF06813.13 EGG14083.1 - 7.8e-26 91.1 7.1 7.8e-26 91.1 7.1 2.6 2 1 0 2 2 2 1 Nodulin-like MFS_1 PF07690.16 EGG14083.1 - 1.5e-21 76.7 50.2 1.2e-09 37.6 1.9 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily UBA_6 PF18039.1 EGG14083.1 - 0.19 11.7 0.6 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain CPBP PF02517.16 EGG14083.1 - 2.2 8.7 13.2 16 6.0 0.2 3.5 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease Macoilin PF09726.9 EGG14083.1 - 5.3 5.5 11.4 8.7 4.8 11.4 1.3 1 0 0 1 1 1 0 Macoilin family NOA36 PF06524.12 EGG14083.1 - 6.5 6.0 8.5 13 5.0 8.5 1.5 1 0 0 1 1 1 0 NOA36 protein DEAD PF00270.29 EGG14084.1 - 4.3e-38 130.8 0.0 1.1e-37 129.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG14084.1 - 4.3e-24 85.0 0.1 4.9e-22 78.4 0.4 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Mg_chelatase PF01078.21 EGG14084.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI 2OG-FeII_Oxy_3 PF13640.6 EGG14085.1 - 3.8e-09 37.3 0.0 6.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nop14 PF04147.12 EGG14085.1 - 0.0022 16.3 20.6 0.0029 15.9 20.6 1.2 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 EGG14085.1 - 0.0023 17.4 15.7 0.0031 16.9 15.7 1.1 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 EGG14085.1 - 0.0034 16.9 21.5 0.0048 16.4 21.5 1.2 1 0 0 1 1 1 1 SDA1 NOA36 PF06524.12 EGG14085.1 - 0.022 14.1 17.6 0.042 13.2 17.6 1.6 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EGG14085.1 - 0.054 11.8 19.0 0.08 11.2 19.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 EGG14085.1 - 0.057 11.9 24.8 0.073 11.5 23.5 1.7 2 0 0 2 2 2 0 Mpp10 protein 2OG-FeII_Oxy PF03171.20 EGG14085.1 - 0.13 12.8 0.0 0.38 11.3 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PPP4R2 PF09184.11 EGG14085.1 - 0.19 11.3 19.2 0.3 10.6 19.2 1.3 1 0 0 1 1 1 0 PPP4R2 RNA_pol_Rpc4 PF05132.14 EGG14085.1 - 0.21 12.0 6.0 0.34 11.3 6.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 EGG14085.1 - 0.28 11.4 7.5 0.53 10.5 7.5 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_3_Rpc31 PF11705.8 EGG14085.1 - 0.38 11.0 25.8 0.76 10.0 25.8 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SAPS PF04499.15 EGG14085.1 - 0.5 9.1 8.0 0.69 8.6 8.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein YL1 PF05764.13 EGG14085.1 - 0.71 9.9 27.0 1.1 9.3 27.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein TFIIA PF03153.13 EGG14085.1 - 0.74 9.7 12.1 1.1 9.2 12.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 EGG14085.1 - 1.1 8.9 19.4 1.7 8.3 19.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RR_TM4-6 PF06459.12 EGG14085.1 - 1.4 8.7 14.4 2.2 8.0 14.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 EGG14085.1 - 2 7.8 12.8 3.5 7.0 12.8 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2722 PF10846.8 EGG14085.1 - 2 7.2 11.2 3 6.7 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) V_ATPase_I PF01496.19 EGG14085.1 - 2.3 6.0 5.3 3.2 5.5 5.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3391 PF11871.8 EGG14085.1 - 2.8 8.5 10.0 5.6 7.5 10.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Presenilin PF01080.17 EGG14085.1 - 2.8 6.6 7.3 4.3 6.0 7.3 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EGG14085.1 - 3.1 6.9 5.3 4.6 6.4 5.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 EGG14085.1 - 3.3 6.6 7.4 4.9 6.0 7.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GCD14 PF08704.10 EGG14085.1 - 3.4 7.3 5.5 9.6 5.8 0.0 2.2 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DUF1682 PF07946.14 EGG14085.1 - 3.7 6.7 15.6 6.4 5.9 15.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Vfa1 PF08432.10 EGG14085.1 - 5.4 7.3 14.6 9.6 6.5 14.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4484 PF14831.6 EGG14085.1 - 5.8 6.9 14.7 11 6.0 14.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Sigma70_ner PF04546.13 EGG14085.1 - 6.6 6.6 29.2 18 5.1 29.2 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region U3_assoc_6 PF08640.11 EGG14086.1 - 1.7e-10 40.8 2.5 2.3e-09 37.2 1.2 3.2 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 baeRF_family6 PF18848.1 EGG14086.1 - 0.00044 20.7 0.2 0.0014 19.0 0.2 1.9 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 6 TPR_14 PF13428.6 EGG14086.1 - 0.0016 19.1 0.0 11 7.1 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat baeRF_family11 PF18855.1 EGG14086.1 - 0.061 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 11 TPR_19 PF14559.6 EGG14086.1 - 0.12 12.9 0.2 8.4 7.0 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.7 EGG14089.1 - 0.00018 21.8 21.9 0.46 11.0 1.6 7.7 7 1 2 9 9 9 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGG14089.1 - 0.0046 17.3 3.2 23 6.0 0.3 6.0 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 EGG14089.1 - 0.017 14.8 9.2 0.12 12.2 2.3 5.4 5 1 1 6 6 6 0 Leucine rich repeat F-box-like PF12937.7 EGG14089.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like SpmSyn_N PF17950.1 EGG14089.1 - 0.12 12.5 0.3 0.53 10.5 0.0 2.2 2 0 0 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal LRR_6 PF13516.6 EGG14089.1 - 0.84 9.8 27.0 0.78 10.0 0.1 7.5 9 0 0 9 9 9 0 Leucine Rich repeat F-box PF00646.33 EGG14089.1 - 2.3 8.2 5.1 4.9 7.1 0.4 2.6 2 0 0 2 2 2 0 F-box domain DUF4116 PF13475.6 EGG14090.1 - 0.078 12.7 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) His_Phos_1 PF00300.22 EGG14091.1 - 4.9e-30 104.7 0.0 7.3e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pro_isomerase PF00160.21 EGG14091.1 - 8.4e-16 58.6 0.1 2.8e-14 53.7 0.1 2.2 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF5633 PF18656.1 EGG14091.1 - 0.26 11.2 1.5 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5633) DUF3884 PF13024.6 EGG14095.1 - 0.0048 16.4 1.5 0.081 12.5 0.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3884) Pkinase PF00069.25 EGG14096.1 - 1.9e-65 220.9 0.0 6.3e-44 150.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG14096.1 - 2.8e-28 98.9 0.2 1.7e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGG14096.1 - 0.0039 17.1 0.0 0.27 11.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGG14096.1 - 0.016 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGG14096.1 - 0.074 12.4 0.0 0.49 9.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like SapB_1 PF05184.15 EGG14098.1 - 3.6e-23 81.2 8.3 9.1e-12 44.8 0.8 3.2 3 1 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.17 EGG14098.1 - 1.4e-13 50.7 9.7 1.8e-06 27.9 0.3 3.6 3 0 0 3 3 3 2 Saposin-like type B, region 2 PHD_4 PF16866.5 EGG14098.1 - 0.15 12.1 8.9 0.21 11.7 0.0 3.9 3 1 2 5 5 5 0 PHD-finger C1_1 PF00130.22 EGG14098.1 - 0.37 10.7 7.4 5 7.1 0.1 3.8 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YtxH PF12732.7 EGG14099.1 - 1.9e-10 41.1 81.7 0.03 14.9 7.9 8.2 3 2 4 7 7 7 6 YtxH-like protein ApoLp-III PF07464.11 EGG14099.1 - 1e-06 28.9 53.7 0.0003 20.9 11.0 5.0 1 1 4 5 5 5 5 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 EGG14099.1 - 0.0001 22.2 37.2 0.079 12.8 7.9 4.4 1 1 2 4 4 4 3 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EGG14099.1 - 0.012 16.2 43.1 0.56 10.8 3.2 7.4 2 1 4 6 6 6 0 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.10 EGG14099.1 - 0.019 15.1 20.1 9 6.5 0.2 6.4 7 0 0 7 7 7 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) MbeB_N PF04837.12 EGG14099.1 - 0.021 15.1 7.0 17 5.8 0.0 4.8 5 0 0 5 5 5 0 MbeB-like, N-term conserved region NFRKB_winged PF14465.6 EGG14099.1 - 0.22 11.7 4.8 74 3.6 0.1 4.0 1 1 3 4 4 4 0 NFRKB Winged Helix-like T7SS_ESX_EspC PF10824.8 EGG14099.1 - 1.9 9.0 24.5 33 5.0 0.4 5.6 2 2 2 5 5 5 0 Excreted virulence factor EspC, type VII ESX diderm Syntaxin-6_N PF09177.11 EGG14099.1 - 2.3 8.8 23.6 1.8 9.2 0.2 5.6 5 2 0 5 5 5 0 Syntaxin 6, N-terminal Prominin PF05478.11 EGG14099.1 - 2.8 5.8 19.4 0.47 8.3 3.6 3.6 1 1 1 3 3 3 0 Prominin Lectin_N PF03954.14 EGG14099.1 - 5.8 6.7 6.9 21 4.9 0.1 3.6 1 1 3 4 4 4 0 Hepatic lectin, N-terminal domain DEAD PF00270.29 EGG14100.1 - 1.5e-52 177.9 0.1 5e-52 176.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG14100.1 - 2.3e-22 79.4 0.1 7.3e-21 74.6 0.1 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EGG14100.1 - 3.3e-11 43.2 12.1 3.3e-11 43.2 12.1 4.3 4 0 0 4 4 4 1 DBP10CT (NUC160) domain NUC173 PF08161.12 EGG14101.1 - 0.0027 17.4 0.3 0.4 10.3 0.1 2.3 1 1 1 2 2 2 2 NUC173 domain UNC45-central PF11701.8 EGG14101.1 - 0.0049 16.8 0.2 0.019 14.9 0.2 2.0 1 1 1 2 2 2 1 Myosin-binding striated muscle assembly central DRIM PF07539.12 EGG14102.1 - 4.4e-80 269.7 16.3 4.4e-80 269.7 16.3 5.1 4 2 0 4 4 4 3 Down-regulated in metastasis HEAT PF02985.22 EGG14102.1 - 0.23 11.8 6.0 43 4.8 0.0 6.1 6 0 0 6 6 6 0 HEAT repeat UME PF08064.13 EGG14102.1 - 3.9 7.4 7.2 13 5.7 0.0 5.4 7 0 0 7 7 7 0 UME (NUC010) domain TRAP_alpha PF03896.16 EGG14102.1 - 4.9 6.3 26.5 0.28 10.3 6.2 3.6 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit Zip PF02535.22 EGG14102.1 - 9.4 5.3 10.3 0.73 9.0 3.8 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Cpn60_TCP1 PF00118.24 EGG14104.1 - 1.1e-165 552.0 0.7 1.3e-165 551.8 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HUN PF08729.10 EGG14105.1 - 1.1e-08 35.0 5.4 6.2e-08 32.5 5.4 2.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain DnaJ PF00226.31 EGG14106.1 - 2e-22 79.1 2.1 6.1e-22 77.5 2.1 1.9 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EGG14106.1 - 0.03 14.2 0.1 0.098 12.6 0.1 1.9 1 0 0 1 1 1 0 A repeated domain in UCH-protein TPT PF03151.16 EGG14107.1 - 4e-46 157.7 22.4 6.7e-46 156.9 22.4 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family EI24 PF07264.11 EGG14107.1 - 3.7e-18 66.4 18.3 3.7e-18 66.4 18.3 2.5 2 1 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) EamA PF00892.20 EGG14107.1 - 4.8e-10 39.7 26.6 2.1e-07 31.2 17.9 3.9 4 1 0 4 4 4 2 EamA-like transporter family UAA PF08449.11 EGG14107.1 - 1.1e-08 34.7 20.1 2.5e-08 33.5 20.1 1.6 1 0 0 1 1 1 1 UAA transporter family TMEM234 PF10639.9 EGG14107.1 - 0.017 15.1 1.2 0.017 15.1 1.2 3.6 3 0 0 3 3 3 0 Putative transmembrane family 234 CtaG_Cox11 PF04442.14 EGG14108.1 - 2.7e-57 193.1 0.1 2.7e-57 193.1 0.1 2.2 2 1 0 2 2 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF2151 PF10221.9 EGG14108.1 - 1.2e-05 24.2 4.4 1.5e-05 23.9 4.4 1.1 1 0 0 1 1 1 1 Cell cycle and development regulator Zip PF02535.22 EGG14108.1 - 0.00075 18.8 1.5 0.00092 18.5 1.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DDHD PF02862.17 EGG14108.1 - 0.0016 18.7 3.2 0.0018 18.5 3.2 1.2 1 0 0 1 1 1 1 DDHD domain Presenilin PF01080.17 EGG14108.1 - 0.0068 15.2 11.4 0.0089 14.8 11.4 1.1 1 0 0 1 1 1 1 Presenilin CAC1F_C PF16885.5 EGG14108.1 - 0.0091 15.7 5.3 0.011 15.4 5.3 1.1 1 0 0 1 1 1 1 Voltage-gated calcium channel subunit alpha, C-term RR_TM4-6 PF06459.12 EGG14108.1 - 0.029 14.2 10.8 0.042 13.7 10.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 EGG14108.1 - 0.034 12.1 6.9 0.042 11.8 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BSMAP PF12280.8 EGG14108.1 - 0.06 13.6 6.0 0.1 12.8 6.0 1.3 1 0 0 1 1 1 0 Brain specific membrane anchored protein GAGA_bind PF06217.12 EGG14108.1 - 0.072 13.4 8.5 0.098 12.9 8.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RP-C_C PF11800.8 EGG14108.1 - 0.091 12.8 5.4 0.12 12.4 5.4 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region TRP PF06011.12 EGG14108.1 - 0.12 11.0 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Folate_carrier PF01770.18 EGG14108.1 - 0.17 10.6 3.2 0.26 10.0 3.2 1.4 1 0 0 1 1 1 0 Reduced folate carrier Mem_trans PF03547.18 EGG14108.1 - 0.23 9.8 1.0 0.25 9.7 1.0 1.3 1 0 0 1 1 1 0 Membrane transport protein HCO3_cotransp PF00955.21 EGG14108.1 - 0.25 10.1 3.3 0.33 9.7 3.3 1.2 1 0 0 1 1 1 0 HCO3- transporter family Ureide_permease PF07168.11 EGG14108.1 - 0.3 9.8 2.6 0.38 9.5 2.6 1.2 1 0 0 1 1 1 0 Ureide permease NPR3 PF03666.13 EGG14108.1 - 0.3 9.8 13.8 0.41 9.4 13.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 EGG14108.1 - 0.41 8.9 12.3 0.56 8.4 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 EGG14108.1 - 0.46 10.9 6.5 0.71 10.3 6.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CLN3 PF02487.17 EGG14108.1 - 0.57 9.2 6.3 0.94 8.5 6.3 1.4 1 0 0 1 1 1 0 CLN3 protein CSG2 PF16965.5 EGG14108.1 - 1.1 8.1 6.1 1.5 7.7 6.1 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Neur_chan_memb PF02932.16 EGG14108.1 - 1.1 9.2 8.2 1.6 8.7 8.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 EGG14108.1 - 1.3 7.8 7.7 1.7 7.5 7.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SLC12 PF03522.15 EGG14108.1 - 6.2 5.7 17.7 8.4 5.3 17.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 ALMT PF11744.8 EGG14108.1 - 6.6 5.4 15.3 8.8 5.0 15.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM60A PF15396.6 EGG14108.1 - 6.8 6.6 15.3 12 5.9 15.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF4407 PF14362.6 EGG14108.1 - 8.4 5.6 7.0 11 5.3 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.6 EGG14108.1 - 8.4 6.5 10.3 15 5.7 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Sec62 PF03839.16 EGG14108.1 - 9.9 5.6 12.3 17 4.9 12.3 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 rRNA_proc-arch PF13234.6 EGG14109.1 - 2.7e-66 224.3 5.7 2.7e-66 224.3 5.7 2.2 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 EGG14109.1 - 8.3e-51 171.9 0.6 2.7e-50 170.3 0.0 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 EGG14109.1 - 4.5e-18 65.6 0.2 2.9e-17 63.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG14109.1 - 1.8e-06 28.3 0.0 2.4e-05 24.7 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGG14109.1 - 0.06 13.6 0.0 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Smg8_Smg9 PF10220.9 EGG14109.1 - 0.08 11.2 7.8 0.14 10.4 7.8 1.3 1 0 0 1 1 1 0 Smg8_Smg9 Homeobox_KN PF05920.11 EGG14111.1 - 5.9e-10 38.9 0.3 1.7e-09 37.5 0.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EGG14111.1 - 9.8e-07 28.5 0.1 9.8e-07 28.5 0.1 2.2 2 0 0 2 2 2 1 Homeodomain UPF0242 PF06785.11 EGG14111.1 - 0.00041 20.5 0.0 0.00041 20.5 0.0 2.8 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus WD40 PF00400.32 EGG14112.1 - 4.9e-31 106.3 28.2 1.3e-06 29.0 1.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_3 PF13570.6 EGG14112.1 - 3.6e-12 46.4 5.6 0.13 12.8 0.0 6.3 7 0 0 7 7 7 4 PQQ-like domain Nup160 PF11715.8 EGG14112.1 - 4e-05 22.5 9.2 0.014 14.0 0.1 4.4 3 2 2 5 5 5 3 Nucleoporin Nup120/160 PI3K_P85_iSH2 PF16454.5 EGG14112.1 - 0.13 11.8 2.2 0.19 11.3 2.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CLZ PF16526.5 EGG14112.1 - 0.19 12.1 1.3 0.31 11.4 1.3 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tropomyosin_1 PF12718.7 EGG14112.1 - 0.3 11.2 2.6 0.42 10.8 2.6 1.2 1 0 0 1 1 1 0 Tropomyosin like Rad52_Rad22 PF04098.15 EGG14113.1 - 3.8e-22 78.9 0.4 7.1e-22 78.0 0.0 1.6 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein Snf7 PF03357.21 EGG14114.1 - 2e-29 102.4 20.5 2e-29 102.4 20.5 2.1 2 0 0 2 2 2 1 Snf7 Myb_DNA-binding PF00249.31 EGG14114.1 - 9.4 6.5 6.5 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Metallophos PF00149.28 EGG14115.1 - 4.4e-14 53.5 1.1 4.4e-14 53.5 1.1 1.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG14115.1 - 1.4e-06 28.6 2.1 2.9e-06 27.6 2.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain UDG PF03167.19 EGG14115.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily WD40 PF00400.32 EGG14116.1 - 9.2e-11 42.1 0.5 0.016 16.1 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat AAA PF00004.29 EGG14117.1 - 9.5e-44 149.0 0.1 2.8e-43 147.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG14117.1 - 8.9e-14 51.0 0.1 1.8e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGG14117.1 - 3.2e-08 33.9 0.0 8.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGG14117.1 - 3.3e-06 27.1 0.0 1.1e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGG14117.1 - 6.4e-06 26.6 0.0 0.00011 22.6 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGG14117.1 - 5.5e-05 23.5 0.9 0.012 15.9 0.9 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGG14117.1 - 8.5e-05 22.4 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_ID_OB PF16450.5 EGG14117.1 - 0.00031 20.6 0.4 0.00086 19.2 0.4 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain TIP49 PF06068.13 EGG14117.1 - 0.0012 18.1 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGG14117.1 - 0.0013 18.9 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG14117.1 - 0.0023 18.5 0.1 0.018 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGG14117.1 - 0.0029 17.4 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EGG14117.1 - 0.0038 17.1 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGG14117.1 - 0.0083 15.5 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EGG14117.1 - 0.0083 15.6 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein MscS_porin PF12795.7 EGG14117.1 - 0.01 15.4 0.5 0.018 14.6 0.5 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain AAA_28 PF13521.6 EGG14117.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGG14117.1 - 0.013 14.9 0.0 0.036 13.4 0.0 1.8 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 EGG14117.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FlaC_arch PF05377.11 EGG14117.1 - 0.018 15.4 5.2 0.033 14.6 2.5 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RNA_helicase PF00910.22 EGG14117.1 - 0.021 15.2 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EGG14117.1 - 0.029 13.9 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGG14117.1 - 0.032 13.9 0.0 0.089 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGG14117.1 - 0.038 13.7 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 EGG14117.1 - 0.039 13.1 0.0 0.089 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 EGG14117.1 - 0.046 14.2 0.1 0.49 10.9 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.17 EGG14117.1 - 0.047 12.8 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EGG14117.1 - 0.054 13.1 0.2 0.16 11.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 EGG14117.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 EGG14117.1 - 0.064 13.8 1.2 0.16 12.5 1.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_17 PF13207.6 EGG14117.1 - 0.072 13.5 0.1 0.25 11.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_13 PF13166.6 EGG14117.1 - 0.088 11.4 0.4 4 6.0 0.4 2.2 2 0 0 2 2 2 0 AAA domain DUF2072 PF09845.9 EGG14117.1 - 0.11 12.7 0.6 0.29 11.4 0.6 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_19 PF13245.6 EGG14117.1 - 0.13 12.6 0.1 0.67 10.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain SlyX PF04102.12 EGG14117.1 - 0.16 12.6 0.8 0.52 11.0 0.8 1.8 1 0 0 1 1 1 0 SlyX DUF2075 PF09848.9 EGG14117.1 - 0.16 11.1 0.7 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 EGG14117.1 - 0.24 11.1 3.5 0.25 11.1 0.2 2.5 2 1 0 2 2 2 0 AAA domain Ras PF00071.22 EGG14118.1 - 3.3e-23 82.1 0.0 4e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG14118.1 - 3.4e-16 59.6 0.0 5.7e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG14118.1 - 1.2e-07 31.4 0.0 1.9e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG14118.1 - 2.7e-06 27.4 0.0 3.8e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG14118.1 - 0.00069 19.6 0.0 0.55 10.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGG14118.1 - 0.0012 18.4 0.0 0.0046 16.5 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EGG14118.1 - 0.0037 16.8 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGG14118.1 - 0.058 13.1 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EGG14118.1 - 0.059 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 EGG14118.1 - 0.065 12.2 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EGG14118.1 - 0.082 13.0 0.2 0.16 12.1 0.0 1.5 2 0 0 2 2 2 0 Dynamin family TniB PF05621.11 EGG14118.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ras PF00071.22 EGG14119.1 - 3.6e-30 104.7 0.0 4.4e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG14119.1 - 1.8e-21 76.6 0.0 3.1e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG14119.1 - 7.8e-11 41.7 0.0 1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG14119.1 - 5.1e-08 32.7 0.0 8.5e-05 22.2 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG14119.1 - 0.0014 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGG14119.1 - 0.0015 18.3 0.0 0.097 12.4 0.0 2.4 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGG14119.1 - 0.0027 17.6 0.1 0.37 10.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EGG14119.1 - 0.0043 16.5 0.0 0.008 15.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGG14119.1 - 0.0076 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGG14119.1 - 0.034 13.3 1.9 0.58 9.3 0.2 2.5 1 1 1 2 2 2 0 G-protein alpha subunit DUF4645 PF15488.6 EGG14119.1 - 0.1 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) Ras PF00071.22 EGG14120.1 - 5.1e-26 91.2 0.0 6.5e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG14120.1 - 6.9e-13 48.9 0.0 1.2e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG14120.1 - 1.2e-07 31.4 0.0 1.5e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG14120.1 - 7.2e-07 28.9 0.1 0.0039 16.8 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG14120.1 - 0.00016 21.7 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG14120.1 - 0.0036 17.2 0.1 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Ras PF00071.22 EGG14121.1 - 1.1e-34 119.4 0.0 1.3e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG14121.1 - 4e-16 59.3 0.0 6.9e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG14121.1 - 4.7e-08 32.7 0.0 5.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG14121.1 - 0.00014 21.5 0.0 0.1 12.2 0.0 2.5 1 1 0 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGG14121.1 - 0.00046 19.7 0.0 0.00069 19.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGG14121.1 - 0.0017 18.1 0.0 0.084 12.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EGG14121.1 - 0.042 13.9 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 EGG14121.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1_Xtn PF16897.5 EGG14121.1 - 0.075 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PI3_PI4_kinase PF00454.27 EGG14122.1 - 6e-60 203.1 0.1 2.2e-59 201.3 0.1 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGG14122.1 - 2.9e-55 186.6 0.3 7.2e-55 185.3 0.3 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_rbd PF00794.18 EGG14122.1 - 1.6e-25 89.3 6.1 1.8e-23 82.7 0.0 3.2 3 0 0 3 3 3 2 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 EGG14122.1 - 4.1e-16 59.2 0.5 4.1e-16 59.2 0.5 3.0 3 0 0 3 3 3 1 Phosphoinositide 3-kinase C2 RBD PF02196.15 EGG14122.1 - 0.029 14.4 0.4 0.18 11.9 0.3 2.3 2 0 0 2 2 2 0 Raf-like Ras-binding domain HEAT_2 PF13646.6 EGG14122.1 - 0.28 11.6 1.3 0.73 10.3 0.3 2.1 2 0 0 2 2 2 0 HEAT repeats UQ_con PF00179.26 EGG14123.1 - 3.6e-45 153.0 0.1 4.5e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGG14123.1 - 3.5e-05 23.7 0.1 5.8e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 EGG14123.1 - 0.004 17.4 0.1 0.0053 17.0 0.0 1.4 1 1 0 1 1 1 1 RWD domain DUF4564 PF15169.6 EGG14124.1 - 3.1e-57 193.3 0.1 3.7e-57 193.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) FAD_SOX PF18371.1 EGG14124.1 - 0.082 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase HECT PF00632.25 EGG14125.1 - 1e-61 209.1 0.6 1e-61 209.1 0.6 2.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 EGG14125.1 - 3.3e-20 72.4 0.4 1.2e-19 70.5 0.4 2.1 1 0 0 1 1 1 1 SPRY domain PH PF00169.29 EGG14125.1 - 7.7e-17 61.7 0.3 3.3e-16 59.7 0.3 2.3 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EGG14125.1 - 2e-08 34.6 1.1 9.9e-08 32.4 1.1 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain CUB PF00431.20 EGG14125.1 - 0.00023 21.5 0.0 0.016 15.5 0.0 3.3 2 0 0 2 2 2 1 CUB domain PH_11 PF15413.6 EGG14125.1 - 0.0069 16.8 0.8 0.0069 16.8 0.8 3.7 3 0 0 3 3 3 1 Pleckstrin homology domain PSD2 PF07624.11 EGG14125.1 - 0.13 12.0 0.0 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) DUF5523 PF17661.1 EGG14126.1 - 0.87 9.2 12.5 0.023 14.4 1.4 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5523) hGDE_N PF14699.6 EGG14127.1 - 0.042 14.0 0.1 0.051 13.7 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme Actin PF00022.19 EGG14129.1 - 6.4e-152 505.9 0.0 2.1e-151 504.2 0.0 1.6 1 1 0 1 1 1 1 Actin RRM_1 PF00076.22 EGG14131.1 - 1.5e-06 28.0 0.2 2.3e-06 27.3 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3446 PF11928.8 EGG14133.1 - 0.031 14.6 18.4 0.04 14.2 18.4 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain PH_10 PF15411.6 EGG14133.1 - 0.064 13.5 0.2 0.079 13.2 0.2 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain DUF2281 PF10047.9 EGG14133.1 - 0.065 13.9 0.1 0.084 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) SR-25 PF10500.9 EGG14133.1 - 0.066 12.8 22.3 0.069 12.8 22.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1117 PF06547.12 EGG14133.1 - 0.2 12.2 4.0 0.2 12.2 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) WD40 PF00400.32 EGG14134.1 - 2.5e-47 157.9 24.5 3e-09 37.3 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG14134.1 - 7.6e-16 58.2 0.1 3.1e-06 27.4 0.0 5.1 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG14134.1 - 2.4e-10 40.3 0.5 0.001 18.5 0.4 3.5 2 2 1 3 3 3 3 WD40-like domain Ge1_WD40 PF16529.5 EGG14134.1 - 2.6e-07 29.9 0.7 0.07 12.1 0.0 3.9 3 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGG14134.1 - 3.2e-07 30.4 0.5 0.0021 17.9 0.0 3.6 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGG14134.1 - 3e-05 22.9 0.1 0.055 12.1 0.1 3.7 3 1 1 4 4 4 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EGG14134.1 - 0.0047 17.4 9.3 8.9 6.9 0.1 5.9 5 1 1 6 6 6 2 PQQ-like domain Nucleoporin_N PF08801.11 EGG14134.1 - 0.0053 15.6 0.1 0.25 10.1 0.0 2.7 2 1 1 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.16 EGG14134.1 - 0.077 11.5 0.1 1.6 7.2 0.0 2.6 2 1 1 4 4 4 0 Cytochrome D1 heme domain Proteasome PF00227.26 EGG14135.1 - 8.4e-23 80.8 0.3 1.4e-22 80.1 0.3 1.4 1 1 0 1 1 1 1 Proteasome subunit DUF5089 PF17002.5 EGG14136.1 - 0.027 14.3 0.0 0.027 14.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5089) Trm5_N PF18093.1 EGG14136.1 - 0.21 11.5 1.8 11 6.1 0.1 2.9 3 0 0 3 3 3 0 tRNA methyltransferase 5 N-terminal domain KIF1B PF12423.8 EGG14136.1 - 0.32 11.5 0.2 0.32 11.5 0.2 2.6 2 0 0 2 2 2 0 Kinesin protein 1B ECH_1 PF00378.20 EGG14137.1 - 2.2e-56 191.0 0.1 2.6e-56 190.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGG14137.1 - 3e-32 112.4 0.0 2e-28 99.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase MDM31_MDM32 PF08118.11 EGG14138.1 - 1.4e-85 288.0 19.0 3.2e-44 151.5 0.1 3.9 1 1 3 4 4 4 3 Yeast mitochondrial distribution and morphology (MDM) proteins Menin PF05053.13 EGG14138.1 - 0.14 10.5 5.8 0.19 10.1 5.8 1.1 1 0 0 1 1 1 0 Menin DUF3439 PF11921.8 EGG14138.1 - 0.52 10.3 12.3 0.2 11.6 5.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Orf78 PF06024.12 EGG14138.1 - 6.3 7.2 6.8 16 5.9 6.8 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Ammonium_transp PF00909.21 EGG14139.1 - 7.1e-91 304.9 19.2 1e-90 304.3 19.2 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family RB_A PF01858.17 EGG14140.1 - 5.7e-50 169.9 2.0 4.6e-48 163.7 0.0 3.1 2 0 0 2 2 2 2 Retinoblastoma-associated protein A domain DUF3452 PF11934.8 EGG14140.1 - 1.2e-19 70.2 5.2 1.2e-19 70.2 5.2 5.4 3 2 1 4 4 4 1 Domain of unknown function (DUF3452) RB_B PF01857.20 EGG14140.1 - 2.1e-16 60.1 9.2 3.7e-14 52.9 5.5 3.7 2 1 0 2 2 2 2 Retinoblastoma-associated protein B domain XPG_N PF00752.17 EGG14141.1 - 1.8e-25 89.3 0.0 1.8e-25 89.3 0.0 2.4 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 EGG14141.1 - 3.4e-19 69.0 0.0 3.4e-19 69.0 0.0 4.2 4 0 0 4 4 4 1 XPG I-region 5_3_exonuc PF01367.20 EGG14141.1 - 0.063 13.9 0.0 0.063 13.9 0.0 4.0 4 1 1 5 5 5 0 5'-3' exonuclease, C-terminal SAM fold Methyltransf_16 PF10294.9 EGG14142.1 - 5.8e-19 68.5 0.7 4.8e-14 52.5 0.0 2.1 1 1 1 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EGG14142.1 - 0.00069 19.5 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF1840 PF08895.11 EGG14142.1 - 0.026 14.8 0.1 0.047 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) GidB PF02527.15 EGG14142.1 - 0.042 13.2 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G AT_hook PF02178.19 EGG14143.1 - 0.1 12.5 5.6 0.29 11.2 5.6 1.8 1 0 0 1 1 1 0 AT hook motif AP3D1 PF06375.11 EGG14143.1 - 7.4 6.8 45.4 0.24 11.6 19.9 3.7 4 0 0 4 4 4 0 AP-3 complex subunit delta-1 Ribosomal_S25 PF03297.15 EGG14144.1 - 2.7e-33 114.2 5.1 3e-33 114.0 5.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein PI3_PI4_kinase PF00454.27 EGG14145.1 - 1.6e-55 188.7 0.0 5.8e-38 131.1 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGG14145.1 - 6.6e-54 182.1 5.2 1.1e-53 181.4 5.2 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 EGG14145.1 - 2e-32 112.0 0.0 8.1e-32 110.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 FlgM PF04316.13 EGG14145.1 - 0.02 15.2 0.4 0.048 14.0 0.4 1.6 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF325 PF03804.13 EGG14145.1 - 0.13 12.3 0.1 0.39 10.8 0.1 1.9 1 0 0 1 1 1 0 Viral proteins of unknown function Mito_carr PF00153.27 EGG14146.1 - 4.5e-62 206.0 2.4 5e-20 71.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein OrfB_Zn_ribbon PF07282.11 EGG14147.1 - 9.2e-06 25.5 0.0 0.0065 16.4 0.0 3.2 2 0 0 2 2 2 2 Putative transposase DNA-binding domain DUF2992 PF11208.8 EGG14147.1 - 0.75 10.0 0.0 0.75 10.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) RICTOR_phospho PF14665.6 EGG14149.1 - 0.00023 21.5 1.0 0.0016 18.7 0.1 2.2 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, phosphorylation-site RCC1 PF00415.18 EGG14150.1 - 2.9e-58 194.3 10.6 2.1e-12 47.5 0.4 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG14150.1 - 7.3e-36 121.3 30.5 1.9e-06 27.5 2.4 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EGG14150.1 - 5.5e-25 87.8 2.8 5.7e-15 55.5 0.1 3.0 2 1 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.6 EGG14150.1 - 0.004 17.4 0.3 0.014 15.7 0.3 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG14150.1 - 0.0048 17.4 0.7 0.47 11.1 0.1 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG14150.1 - 0.025 15.2 4.0 0.13 12.9 1.3 3.1 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) MCM PF00493.23 EGG14151.1 - 2.1e-101 337.7 0.0 3.5e-101 337.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGG14151.1 - 2.7e-30 104.8 0.1 5.4e-30 103.8 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGG14151.1 - 1.8e-20 73.2 1.5 4e-20 72.0 1.5 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGG14151.1 - 5.6e-09 36.5 1.4 2e-08 34.7 0.3 2.6 3 0 0 3 3 2 1 MCM N-terminal domain AAA_5 PF07728.14 EGG14151.1 - 5e-08 33.0 0.0 5.3e-06 26.5 0.0 3.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGG14151.1 - 2e-07 30.6 0.2 3.2e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGG14151.1 - 0.0027 17.6 0.0 0.0074 16.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EGG14151.1 - 0.0028 17.5 0.1 0.0058 16.4 0.1 1.4 1 0 0 1 1 1 1 AAA lid domain MCM_bind PF09739.9 EGG14151.1 - 0.026 13.0 0.0 0.051 12.0 0.0 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Sigma54_activat PF00158.26 EGG14151.1 - 0.12 12.1 0.1 0.46 10.2 0.1 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 EGG14151.1 - 0.2 11.6 0.6 25 4.7 0.0 2.4 1 1 1 2 2 2 0 NTPase FXMRP1_C_core PF12235.8 EGG14151.1 - 1.5 9.4 4.5 3.2 8.4 4.5 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Ribosomal_L20 PF00453.18 EGG14152.1 - 1e-26 93.1 4.0 4.7e-25 87.7 1.7 2.6 2 0 0 2 2 2 2 Ribosomal protein L20 Sec63 PF02889.16 EGG14153.1 - 1.4e-27 96.5 2.0 5.3e-17 61.8 1.8 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.31 EGG14153.1 - 2.3e-19 69.3 0.1 1e-18 67.2 0.1 2.2 1 0 0 1 1 1 1 DnaJ domain TFIIA PF03153.13 EGG14153.1 - 7.8e-05 22.8 15.1 7.8e-05 22.8 15.1 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 EGG14153.1 - 0.0005 19.5 31.2 0.0005 19.5 31.2 2.2 2 0 0 2 2 2 1 BUD22 ODV-E18 PF10717.9 EGG14153.1 - 0.016 15.1 1.2 4.7 7.1 0.3 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 FeoB_associated PF12669.7 EGG14153.1 - 0.057 13.8 0.1 0.057 13.8 0.1 2.9 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein YppG PF14179.6 EGG14153.1 - 0.43 11.3 21.0 4 8.2 17.3 2.9 2 0 0 2 2 2 0 YppG-like protein GWT1 PF06423.12 EGG14153.1 - 1.7 8.7 4.4 0.9 9.7 0.0 2.7 3 0 0 3 3 3 0 GWT1 ETRAMP PF09716.10 EGG14154.1 - 0.057 13.5 1.3 0.076 13.1 1.3 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Pentapeptide_4 PF13599.6 EGG14154.1 - 0.075 13.2 4.5 0.14 12.3 4.5 1.5 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Rad10 PF03834.14 EGG14156.1 - 1.1e-32 112.4 0.1 2.3e-32 111.4 0.1 1.6 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EGG14156.1 - 0.0034 17.9 0.0 0.0072 16.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Gti1_Pac2 PF09729.9 EGG14156.1 - 0.26 11.3 9.9 0.47 10.5 9.9 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family adh_short PF00106.25 EGG14157.1 - 1.5e-15 57.2 0.0 1.5e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG14157.1 - 2.2e-10 40.5 0.0 4.1e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG14157.1 - 0.022 14.7 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 EGG14157.1 - 0.06 12.8 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family MAF_flag10 PF01973.18 EGG14157.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF115 MDD_C PF18376.1 EGG14158.1 - 0.02 14.7 1.9 0.03 14.1 1.9 1.3 1 0 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain Aminotran_1_2 PF00155.21 EGG14159.1 - 3.5e-57 194.2 0.0 4e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGG14159.1 - 2.5e-05 23.4 0.0 6.7e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGG14159.1 - 7.5e-05 21.4 0.0 0.00013 20.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGG14159.1 - 0.032 13.5 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Pro-kuma_activ PF09286.11 EGG14159.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain BAR PF03114.18 EGG14160.1 - 0.00042 20.0 5.6 0.0018 17.9 5.6 1.9 1 1 0 1 1 1 1 BAR domain DUF713 PF05218.14 EGG14160.1 - 0.0029 17.4 3.5 0.0029 17.4 3.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF713) MBOAT PF03062.19 EGG14161.1 - 2e-21 76.8 29.0 8.9e-21 74.6 29.0 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EGG14161.1 - 0.00032 20.9 7.0 0.00048 20.3 5.6 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family CDP-OH_P_transf PF01066.21 EGG14162.1 - 1.7e-17 63.9 0.0 1.7e-17 63.9 0.0 3.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FH2 PF02181.23 EGG14163.1 - 4.4e-78 263.0 0.6 4.4e-78 263.0 0.6 2.6 3 1 1 4 4 4 1 Formin Homology 2 Domain DUF3361 PF11841.8 EGG14163.1 - 6.6e-07 29.4 0.0 2e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) DUF2990 PF11693.8 EGG14163.1 - 0.054 13.6 0.0 0.37 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) SOGA PF11365.8 EGG14163.1 - 1.4 10.0 10.5 16 6.7 2.7 3.5 2 1 0 2 2 2 0 Protein SOGA Pox_A_type_inc PF04508.12 EGG14163.1 - 6.7 6.7 5.9 11 6.0 2.8 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Med1 PF10744.9 EGG14165.1 - 6.2e-20 71.6 3.7 2.8e-19 69.5 3.7 1.9 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 G_glu_transpept PF01019.21 EGG14165.1 - 6.4e-05 21.9 0.2 0.00011 21.1 0.2 1.3 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3882 PF07066.11 EGG14165.1 - 0.018 15.1 0.0 0.062 13.4 0.0 1.8 1 0 0 1 1 1 0 Lactococcus phage M3 protein FA_FANCE PF11510.8 EGG14165.1 - 0.52 9.6 3.7 0.26 10.6 0.7 2.0 2 1 2 4 4 4 0 Fanconi Anaemia group E protein FANCE CBM_25 PF03423.13 EGG14165.1 - 1.7 9.0 4.1 21 5.4 0.0 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) EST1 PF10374.9 EGG14165.1 - 4.4 8.0 7.4 38 4.9 7.4 2.5 1 1 0 1 1 1 0 Telomerase activating protein Est1 KLRAQ PF10205.9 EGG14165.1 - 4.6 7.5 9.1 0.19 12.0 0.9 2.7 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein IZUMO PF15005.6 EGG14165.1 - 7.1 7.1 7.2 0.49 10.9 1.2 2.1 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated EamA PF00892.20 EGG14166.1 - 3e-06 27.5 13.3 3e-06 27.5 13.3 3.1 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 EGG14166.1 - 2.5e-05 23.9 12.5 4.9e-05 23.0 12.5 1.4 1 0 0 1 1 1 1 Solute carrier family 35 EBP PF05241.12 EGG14166.1 - 0.098 12.1 1.8 0.18 11.3 1.8 1.4 1 0 0 1 1 1 0 Emopamil binding protein DUF418 PF04235.12 EGG14166.1 - 0.24 11.3 5.6 4.5 7.2 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF418) RabGAP-TBC PF00566.18 EGG14168.1 - 1.9e-19 70.2 3.1 1.9e-19 70.2 3.1 2.9 3 0 0 3 3 3 2 Rab-GTPase-TBC domain AbiJ_NTD4 PF18863.1 EGG14168.1 - 2.9 8.3 14.9 0.096 13.1 4.4 2.8 2 2 0 2 2 2 0 AbiJ N-terminal domain 4 EGF_CA PF07645.15 EGG14169.1 - 1e-27 96.0 92.9 1.5e-10 41.1 10.6 7.4 6 1 0 6 6 6 4 Calcium-binding EGF domain cEGF PF12662.7 EGG14169.1 - 2.2e-13 49.9 34.5 1e-05 25.3 3.2 5.9 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 EGG14169.1 - 9.2e-06 25.6 7.3 9.2e-06 25.6 7.3 6.5 7 0 0 7 7 7 3 MSP1 EGF domain 1 EGF PF00008.27 EGG14169.1 - 0.0023 18.2 6.3 0.0023 18.2 6.3 7.4 6 0 0 6 6 6 4 EGF-like domain EGF_3 PF12947.7 EGG14169.1 - 0.0059 16.8 17.2 0.012 15.8 9.4 7.0 7 0 0 7 7 7 4 EGF domain hEGF PF12661.7 EGG14169.1 - 0.013 16.1 5.0 0.013 16.1 5.0 8.4 8 0 0 8 8 8 0 Human growth factor-like EGF TIG PF01833.24 EGG14169.1 - 0.033 14.3 14.4 0.51 10.5 0.1 4.8 4 1 0 4 4 4 0 IPT/TIG domain EGF_2 PF07974.13 EGG14169.1 - 0.92 9.9 93.2 0.024 15.0 7.7 6.7 6 0 0 6 6 6 0 EGF-like domain DAGAT PF03982.13 EGG14170.1 - 1.4e-104 349.2 0.0 1.6e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Mss4 PF04421.13 EGG14171.1 - 3.9e-17 62.2 0.2 3.9e-17 62.2 0.2 2.1 2 1 0 2 2 2 1 Mss4 protein Eapp_C PF10238.9 EGG14171.1 - 0.026 14.6 3.3 0.15 12.1 1.9 2.0 2 0 0 2 2 2 0 E2F-associated phosphoprotein RNA_POL_M_15KD PF02150.16 EGG14171.1 - 0.23 11.4 4.9 4.9 7.1 0.3 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit V-ATPase_G PF03179.15 EGG14172.1 - 2e-28 99.0 11.9 2.2e-28 98.8 11.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EGG14172.1 - 0.014 15.5 10.3 0.014 15.5 10.3 1.4 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 EGG14172.1 - 0.03 14.7 7.4 0.045 14.2 7.4 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit AAT PF03417.16 EGG14172.1 - 0.033 13.9 0.7 0.037 13.7 0.7 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase FliD_N PF02465.18 EGG14172.1 - 0.19 12.4 7.7 0.27 11.9 7.7 1.4 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus AcylCoA_dehyd_C PF12186.8 EGG14172.1 - 0.28 11.3 4.6 0.32 11.1 3.7 1.5 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal DUF3135 PF11333.8 EGG14172.1 - 0.48 10.7 4.8 0.71 10.2 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) FlgM PF04316.13 EGG14172.1 - 0.53 10.7 5.0 0.54 10.7 3.8 1.7 1 1 1 2 2 2 0 Anti-sigma-28 factor, FlgM Cupin_8 PF13621.6 EGG14173.1 - 2.9e-40 138.6 1.8 4.5e-40 138.0 1.8 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGG14173.1 - 2.4e-12 47.0 0.0 9.8e-12 45.0 0.0 2.0 2 1 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 EGG14173.1 - 1.7e-05 25.2 0.2 4.9e-05 23.7 0.2 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EGG14173.1 - 0.0005 19.7 0.0 0.00095 18.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGG14173.1 - 0.015 15.2 0.0 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_1 PF00190.22 EGG14173.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Cupin Kelch_1 PF01344.25 EGG14174.1 - 3.1e-50 167.5 1.8 2.5e-08 33.4 0.0 6.1 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGG14174.1 - 1.3e-44 150.0 14.6 2.2e-10 40.4 0.0 6.1 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 EGG14174.1 - 4.3e-42 140.6 9.0 1.8e-08 34.0 0.1 6.1 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EGG14174.1 - 8.3e-41 137.0 8.1 2.7e-07 30.6 0.0 6.1 3 1 3 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGG14174.1 - 1.1e-38 130.8 11.8 6.7e-09 35.8 0.1 6.4 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG14174.1 - 4.7e-37 125.4 7.8 2.3e-08 33.8 0.0 6.0 6 0 0 6 6 6 5 Kelch motif PQQ_3 PF13570.6 EGG14174.1 - 0.15 12.6 8.6 8.9 6.9 0.1 5.3 4 1 1 5 5 5 0 PQQ-like domain tRNA-synt_1g PF09334.11 EGG14175.1 - 3.3e-152 506.8 0.2 4.4e-152 506.4 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 EGG14175.1 - 1.3e-18 66.9 0.2 2.4e-18 66.0 0.2 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 EGG14175.1 - 1.8e-08 33.1 3.0 9.2e-05 20.9 0.0 3.3 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGG14175.1 - 2.6e-05 24.2 0.0 5.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DZR PF12773.7 EGG14175.1 - 2.1 8.5 10.0 15 5.7 7.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 EGG14175.1 - 3.4 7.7 8.7 2.8 8.0 1.1 2.0 1 1 1 2 2 2 0 zinc-ribbons AAA_22 PF13401.6 EGG14176.1 - 0.00012 22.3 0.1 0.00049 20.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGG14176.1 - 0.00032 20.7 0.6 0.0033 17.3 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 EGG14176.1 - 0.00067 19.7 0.6 0.0037 17.3 0.6 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EGG14176.1 - 0.0022 17.7 0.1 0.0053 16.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Roc PF08477.13 EGG14176.1 - 0.0048 17.1 0.8 0.085 13.1 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EGG14176.1 - 0.0076 16.8 4.5 0.018 15.6 4.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG14176.1 - 0.0076 16.7 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EGG14176.1 - 0.0099 16.4 3.3 0.028 14.9 3.3 2.0 1 1 0 1 1 1 1 ABC transporter TniB PF05621.11 EGG14176.1 - 0.015 14.7 0.0 0.27 10.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EGG14176.1 - 0.039 13.4 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 EGG14176.1 - 0.054 13.5 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGG14176.1 - 0.12 12.5 0.3 3.4 7.8 0.3 2.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EGG14176.1 - 0.18 12.2 0.2 1 9.8 0.0 2.4 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) zf-AN1 PF01428.16 EGG14176.1 - 3.9 7.7 11.2 11 6.2 11.2 1.8 1 0 0 1 1 1 0 AN1-like Zinc finger Patatin PF01734.22 EGG14177.1 - 1.8e-18 67.5 0.0 5.4e-18 65.9 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase MMR_HSR1 PF01926.23 EGG14177.1 - 0.077 13.1 0.0 0.29 11.2 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase JmjC PF02373.22 EGG14178.1 - 2.1e-39 134.5 0.1 1.4e-38 131.8 0.1 2.5 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 EGG14178.1 - 3.5e-20 72.4 0.2 2.6e-19 69.7 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 EGG14178.1 - 1e-16 60.6 3.6 1e-16 60.6 3.6 2.1 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 EGG14178.1 - 0.00071 19.9 14.7 0.2 12.1 10.0 2.6 2 0 0 2 2 2 2 C5HC2 zinc finger Myb_DNA-bind_5 PF13873.6 EGG14178.1 - 0.035 14.2 0.3 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain MMR_HSR1 PF01926.23 EGG14179.1 - 1.3e-13 51.1 1.0 3.1e-06 27.2 0.1 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_33 PF13671.6 EGG14179.1 - 1.2e-06 28.8 0.0 0.014 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EGG14179.1 - 6.1e-06 26.8 0.3 0.0049 17.4 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_22 PF13401.6 EGG14179.1 - 1.4e-05 25.4 0.0 0.18 12.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EGG14179.1 - 2e-05 24.2 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain zf-B_box PF00643.24 EGG14179.1 - 7.7e-05 22.8 4.3 7.7e-05 22.8 4.3 3.2 4 0 0 4 4 2 2 B-box zinc finger RsgA_GTPase PF03193.16 EGG14179.1 - 8.7e-05 22.5 2.0 0.029 14.3 0.0 3.5 3 0 0 3 3 3 1 RsgA GTPase AAA_7 PF12775.7 EGG14179.1 - 0.00018 21.1 0.1 3 7.3 0.0 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_24 PF13479.6 EGG14179.1 - 0.00038 20.3 0.6 1.4 8.6 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EGG14179.1 - 0.00062 20.0 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGG14179.1 - 0.00064 20.1 1.7 3.5 8.1 0.0 5.2 6 0 0 6 6 6 1 RNA helicase AAA_16 PF13191.6 EGG14179.1 - 0.00081 19.8 0.0 0.19 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EGG14179.1 - 0.00097 18.4 0.0 1.3 8.1 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain Roc PF08477.13 EGG14179.1 - 0.0019 18.4 0.2 5.2 7.3 0.0 4.0 5 0 0 5 5 3 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGG14179.1 - 0.0059 16.2 0.0 1.3 8.6 0.0 3.6 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EGG14179.1 - 0.0091 16.5 0.0 4.3 7.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain YflT PF11181.8 EGG14179.1 - 0.013 16.0 1.5 0.046 14.2 0.7 2.4 2 0 0 2 2 1 0 Heat induced stress protein YflT AAA_21 PF13304.6 EGG14179.1 - 0.018 14.9 4.3 0.15 11.8 0.0 3.6 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGG14179.1 - 0.022 15.3 0.0 0.022 15.3 0.0 3.6 3 1 1 4 4 4 0 AAA domain cobW PF02492.19 EGG14179.1 - 0.023 14.3 0.1 6.4 6.3 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EGG14179.1 - 0.031 14.7 0.2 6 7.3 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGG14179.1 - 0.039 14.0 0.0 7.9 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 EGG14179.1 - 0.065 13.0 0.6 9.8 5.8 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EGG14179.1 - 0.09 12.8 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGG14179.1 - 0.11 11.9 0.0 8.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MobB PF03205.14 EGG14179.1 - 0.11 12.3 1.4 5.7 6.9 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B FNIP PF05725.12 EGG14180.1 - 4.6e-49 164.3 38.1 1.2e-16 60.6 0.1 7.6 8 1 1 9 9 9 5 FNIP Repeat Pkinase PF00069.25 EGG14180.1 - 3.2e-17 62.8 1.8 8.2e-17 61.4 1.8 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG14180.1 - 6.7e-07 28.8 0.0 4.5e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase ANAPC10 PF03256.16 EGG14181.1 - 4e-60 202.6 0.1 4.6e-60 202.4 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 EGG14181.1 - 0.0003 20.9 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 EGG14181.1 - 0.0011 19.2 0.2 0.0014 18.9 0.2 1.2 1 0 0 1 1 1 1 PITH domain zf-CCHC PF00098.23 EGG14182.1 - 3.3e-27 93.3 37.3 5.4e-06 26.2 1.6 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 EGG14182.1 - 3e-06 26.8 29.3 0.12 12.1 2.3 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.6 EGG14182.1 - 1.1e-05 25.2 1.6 1.1e-05 25.2 1.6 5.5 5 0 0 5 5 5 2 Zinc knuckle zf-CCHC_6 PF15288.6 EGG14182.1 - 0.0042 16.9 13.5 0.03 14.1 1.2 4.9 5 0 0 5 5 5 2 Zinc knuckle zf-CCHC_3 PF13917.6 EGG14182.1 - 0.034 14.1 29.8 2.1 8.4 1.3 5.1 1 1 4 5 5 5 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGG14182.1 - 0.2 11.4 0.6 0.2 11.4 0.6 5.4 4 1 1 5 5 5 0 C2H2 zinc-finger Rpr2 PF04032.16 EGG14183.1 - 4.4e-16 58.9 2.3 4.4e-16 58.9 2.3 3.4 4 1 0 4 4 4 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain ADK_lid PF05191.14 EGG14183.1 - 0.69 9.9 0.0 0.69 9.9 0.0 2.8 3 0 0 3 3 3 0 Adenylate kinase, active site lid BAR PF03114.18 EGG14184.1 - 6.5e-18 65.2 8.0 8.7e-18 64.8 8.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EGG14184.1 - 2e-11 43.3 0.0 3.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGG14184.1 - 2.4e-11 43.3 0.0 4.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGG14184.1 - 1.2e-05 24.8 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Casc1 PF12366.8 EGG14184.1 - 0.046 13.3 1.5 0.076 12.5 1.5 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Arfaptin PF06456.13 EGG14184.1 - 0.11 12.1 4.4 0.21 11.1 4.4 1.5 1 1 0 1 1 1 0 Arfaptin-like domain PAP2 PF01569.21 EGG14185.1 - 0.00012 21.9 2.6 0.00074 19.3 0.7 3.1 2 1 1 3 3 3 1 PAP2 superfamily Ni_hydr_CYTB PF01292.20 EGG14185.1 - 0.11 12.1 7.3 0.022 14.3 2.0 2.5 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 Mannosyl_trans PF05007.13 EGG14186.1 - 1.7e-77 260.8 28.0 4e-77 259.6 28.0 1.6 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EGG14186.1 - 2.2e-09 36.9 18.2 2.2e-09 36.9 18.2 2.5 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U Dsh_C PF12316.8 EGG14187.1 - 0.21 12.0 4.6 0.31 11.4 4.6 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Period_C PF12114.8 EGG14187.1 - 2.3 7.7 4.9 3.7 7.1 4.9 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region VWA_2 PF13519.6 EGG14189.1 - 0.064 13.9 0.1 0.23 12.1 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain SR-25 PF10500.9 EGG14189.1 - 3.1 7.4 15.7 0.34 10.5 8.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein LRR_6 PF13516.6 EGG14190.1 - 1.3e-10 40.5 57.6 0.012 15.6 0.7 13.2 14 0 0 14 14 14 6 Leucine Rich repeat LRR_4 PF12799.7 EGG14190.1 - 0.00013 22.2 43.0 0.57 10.7 0.9 8.5 5 1 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGG14190.1 - 0.0058 17.0 32.1 5.8 7.9 0.1 11.2 13 1 0 13 13 13 3 Leucine Rich Repeat F-box-like PF12937.7 EGG14190.1 - 0.034 14.0 0.2 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EGG14190.1 - 0.05 13.5 0.2 0.65 9.9 0.0 2.7 2 1 0 2 2 2 0 F-box domain LRR_8 PF13855.6 EGG14190.1 - 2.6 7.9 44.4 0.24 11.2 2.1 9.1 3 3 3 6 6 6 0 Leucine rich repeat LRR_4 PF12799.7 EGG14191.1 - 0.26 11.8 2.9 6.6 7.3 1.2 3.6 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) RGS PF00615.19 EGG14192.1 - 6.8e-14 52.1 0.4 1.1e-13 51.4 0.4 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF92 PF01940.16 EGG14193.1 - 2.5e-80 269.3 0.4 3e-80 269.1 0.4 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 VARLMGL PF14383.6 EGG14193.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 DUF761-associated sequence motif DUF4271 PF14093.6 EGG14193.1 - 0.063 13.2 3.4 0.094 12.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF389 PF04087.14 EGG14193.1 - 0.094 12.7 5.0 1.5 8.8 0.7 3.0 3 2 0 3 3 3 0 Domain of unknown function (DUF389) Enoyl_reductase PF12241.8 EGG14193.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Phage_holin_2_1 PF04971.12 EGG14193.1 - 0.39 10.8 8.3 3.4 7.7 1.3 3.1 2 1 0 2 2 2 0 Bacteriophage P21 holin S Syndecan PF01034.20 EGG14193.1 - 4.8 7.2 8.8 7.1 6.6 1.1 3.7 2 1 1 3 3 3 0 Syndecan domain FeS_assembly_P PF01883.19 EGG14194.1 - 3.4e-13 49.6 0.0 5.6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Nucleoporin_FG PF13634.6 EGG14195.1 - 6.9e-05 23.6 86.5 0.0031 18.3 35.0 5.1 2 1 2 4 4 4 1 Nucleoporin FG repeat region Rad9_Rad53_bind PF08605.10 EGG14195.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding Staphostatin_A PF09022.10 EGG14195.1 - 0.35 10.8 6.2 3.9 7.4 0.4 2.9 3 0 0 3 3 3 0 Staphostatin A Nucleoporin_FG PF13634.6 EGG14196.1 - 2.6e-11 44.2 54.8 2.1e-06 28.5 17.8 3.8 2 1 0 2 2 2 2 Nucleoporin FG repeat region ABC_membrane PF00664.23 EGG14197.1 - 2e-33 116.2 18.4 2.7e-33 115.8 18.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGG14197.1 - 4e-33 114.8 0.0 8.4e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGG14197.1 - 7.4e-06 25.5 0.8 0.0011 18.4 0.1 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain DEAD PF00270.29 EGG14197.1 - 2e-05 24.4 0.0 3.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_23 PF13476.6 EGG14197.1 - 0.00061 20.3 0.1 0.0021 18.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 EGG14197.1 - 0.0028 17.7 0.1 0.0085 16.2 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EGG14197.1 - 0.0035 17.1 0.0 0.0077 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGG14197.1 - 0.0041 17.4 0.1 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGG14197.1 - 0.0052 17.2 0.1 0.012 15.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 EGG14197.1 - 0.0094 16.1 0.1 0.032 14.3 0.1 1.9 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_29 PF13555.6 EGG14197.1 - 0.022 14.5 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EGG14197.1 - 0.026 14.5 0.1 1.5 8.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EGG14197.1 - 0.037 13.9 0.1 0.12 12.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGG14197.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_10 PF12846.7 EGG14197.1 - 0.094 11.6 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.15 EGG14197.1 - 0.11 12.4 0.6 2.6 7.9 0.1 2.3 2 0 0 2 2 2 0 NTPase AAA PF00004.29 EGG14197.1 - 0.17 12.3 0.3 2.5 8.5 0.3 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF202 PF02656.15 EGG14198.1 - 5.5 7.5 9.6 16 6.0 3.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Sec23_trunk PF04811.15 EGG14199.1 - 8.8e-17 61.5 0.1 8.8e-17 61.5 0.1 2.2 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 EGG14199.1 - 3.6e-08 33.3 7.3 1.1e-07 31.8 7.3 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EGG14199.1 - 1.7e-06 28.6 0.0 1.7e-06 28.6 0.0 2.3 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain zf-piccolo PF05715.13 EGG14199.1 - 0.031 14.4 3.2 0.11 12.7 3.2 1.9 1 0 0 1 1 1 0 Piccolo Zn-finger Gelsolin PF00626.22 EGG14199.1 - 0.056 13.3 0.0 0.056 13.3 0.0 2.4 2 0 0 2 2 2 0 Gelsolin repeat FYVE_2 PF02318.16 EGG14199.1 - 0.07 13.3 1.1 0.22 11.7 1.1 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger zinc_ribbon_10 PF10058.9 EGG14199.1 - 1.6 8.5 4.8 3.6 7.4 4.8 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Mrx7 PF10906.8 EGG14199.1 - 3.7 7.9 8.6 6 7.2 0.0 3.4 3 0 0 3 3 3 0 MIOREX complex component 7 G-alpha PF00503.20 EGG14200.1 - 3e-61 207.6 0.2 2e-55 188.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit PH PF00169.29 EGG14200.1 - 4.3e-14 52.9 4.4 8.6e-14 51.9 2.9 2.3 2 1 0 2 2 2 1 PH domain Arf PF00025.21 EGG14200.1 - 1.7e-08 34.1 0.8 3.4e-05 23.4 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGG14200.1 - 0.0011 19.1 3.6 1.7 8.9 0.0 3.7 3 1 1 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase PH_9 PF15410.6 EGG14200.1 - 0.0036 17.7 1.0 0.0036 17.7 1.0 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 EGG14200.1 - 0.013 15.7 5.7 0.2 11.9 0.1 2.8 2 1 1 3 3 3 0 Pleckstrin homology domain PH_11 PF15413.6 EGG14200.1 - 0.019 15.4 3.7 0.019 15.4 3.7 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain Gtr1_RagA PF04670.12 EGG14200.1 - 0.064 12.6 2.5 5.9 6.2 0.0 2.8 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region PH_5 PF15405.6 EGG14200.1 - 0.12 12.5 2.4 0.11 12.6 0.6 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain EST1 PF10374.9 EGG14200.1 - 0.4 11.3 5.3 1.1 9.8 0.3 3.2 2 1 1 3 3 3 0 Telomerase activating protein Est1 Rsa3 PF14615.6 EGG14201.1 - 1.5e-13 50.1 0.3 4.1e-13 48.7 0.3 1.8 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Mitofilin PF09731.9 EGG14201.1 - 7.1 5.3 50.6 14 4.4 50.6 1.5 1 0 0 1 1 1 0 Mitochondrial inner membrane protein adh_short PF00106.25 EGG14203.1 - 7.1e-33 113.7 0.0 9.5e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG14203.1 - 3.4e-22 79.1 0.0 4.8e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG14203.1 - 7.4e-07 29.2 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EGG14203.1 - 0.022 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SURF6 PF04935.12 EGG14204.1 - 2.9e-27 95.8 41.8 2.9e-27 95.8 41.8 3.2 3 1 1 4 4 4 1 Surfeit locus protein 6 SNAP PF14938.6 EGG14205.1 - 7.5e-106 353.7 21.9 8.5e-106 353.5 21.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EGG14205.1 - 8.6e-12 45.2 12.8 9.4e-07 29.0 2.6 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG14205.1 - 1.9e-08 33.8 6.8 0.01 15.8 0.1 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG14205.1 - 3.3e-07 29.9 26.2 0.071 13.3 1.1 6.8 5 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGG14205.1 - 4.3e-06 27.1 10.2 0.41 11.6 0.2 6.4 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGG14205.1 - 5.1e-06 26.1 2.9 5.1e-06 26.1 2.9 1.5 2 0 0 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 EGG14205.1 - 7.7e-06 25.7 21.8 0.021 15.0 0.2 6.1 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG14205.1 - 2.5e-05 24.6 21.4 0.66 10.7 0.5 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat DHR-2 PF06920.13 EGG14205.1 - 7e-05 21.7 2.2 7e-05 21.7 2.2 2.3 1 1 1 2 2 2 1 Dock homology region 2 TPR_16 PF13432.6 EGG14205.1 - 7.7e-05 23.3 6.4 0.13 13.0 0.1 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG14205.1 - 0.00019 21.9 14.1 0.47 11.0 0.6 5.7 2 1 4 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGG14205.1 - 0.00048 19.7 8.6 0.94 9.2 0.0 5.0 5 0 0 5 5 5 2 TPR repeat Spatacsin_C PF14649.6 EGG14205.1 - 0.0026 17.0 10.9 0.032 13.4 7.8 2.9 1 1 2 3 3 3 1 Spatacsin C-terminus DUF2225 PF09986.9 EGG14205.1 - 0.0027 17.4 6.3 0.045 13.5 6.4 2.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 EGG14205.1 - 0.0074 16.1 11.7 7 6.7 0.0 5.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG14205.1 - 0.0077 16.0 27.0 0.96 9.4 1.2 6.2 6 1 1 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG14205.1 - 0.016 15.4 12.1 0.25 11.6 0.8 3.7 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 EGG14205.1 - 0.019 15.4 0.6 0.46 10.9 1.0 2.7 1 1 0 2 2 2 0 Bacterial transcriptional activator domain RPN7 PF10602.9 EGG14205.1 - 0.11 12.3 8.0 0.16 11.6 2.1 3.2 1 1 3 4 4 4 0 26S proteasome subunit RPN7 NSF PF02071.20 EGG14205.1 - 0.21 12.5 27.4 17 6.8 0.9 8.1 6 1 1 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat FRB_dom PF08771.11 EGG14205.1 - 0.83 10.1 3.6 2 8.9 0.3 2.7 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain tRNA-synt_2_TM PF16995.5 EGG14207.1 - 0.076 12.7 1.3 4.2 7.0 0.1 3.0 3 0 0 3 3 3 0 Transmembrane region of lysyl-tRNA synthetase DUF805 PF05656.14 EGG14207.1 - 2.4 8.6 6.4 29 5.1 2.1 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Pkinase_Tyr PF07714.17 EGG14208.1 - 4.9e-60 203.0 0.1 1.4e-59 201.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGG14208.1 - 2.5e-49 168.0 0.0 6e-49 166.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGG14208.1 - 8.6e-07 28.1 2.4 2.5e-06 26.5 2.4 1.7 1 1 0 1 1 1 1 Fungal protein kinase SH2 PF00017.24 EGG14208.1 - 1.2e-05 25.4 0.0 3.6e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Cbl_N2 PF02761.14 EGG14208.1 - 1.4e-05 25.7 0.2 5.2e-05 23.9 0.2 1.9 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain APH PF01636.23 EGG14208.1 - 0.12 12.2 0.0 0.44 10.4 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2828 PF11443.8 EGG14208.1 - 0.3 9.1 4.1 0.46 8.5 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Hydin_ADK PF17213.3 EGG14208.1 - 0.86 9.9 5.0 1.6 9.0 5.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Activator_LAG-3 PF11498.8 EGG14208.1 - 7.8 5.3 26.8 11 4.9 26.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 p450 PF00067.22 EGG14209.1 - 4.1e-77 259.9 0.0 4.7e-77 259.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WASH-7_C PF14746.6 EGG14209.1 - 0.09 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal NIF PF03031.18 EGG14210.1 - 9e-22 77.5 0.3 1.9e-21 76.5 0.3 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 EGG14210.1 - 1.4e-05 24.7 0.0 5.5e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Chlam_PMP PF02415.17 EGG14210.1 - 0.0005 20.4 48.4 0.16 12.5 0.3 10.2 10 0 0 10 10 10 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat BSMAP PF12280.8 EGG14210.1 - 0.045 14.0 4.8 0.56 10.4 0.0 3.2 3 0 0 3 3 3 0 Brain specific membrane anchored protein PmoA PF14100.6 EGG14210.1 - 0.18 11.3 0.9 15 5.0 0.0 2.2 2 0 0 2 2 2 0 Methane oxygenase PmoA DUF4957 PF16318.5 EGG14210.1 - 2 8.3 13.2 0.062 13.2 4.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4957) PG_binding_1 PF01471.18 EGG14211.1 - 2.4e-06 27.7 0.0 4.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain YkuD PF03734.14 EGG14211.1 - 7.4e-06 26.4 0.0 1.2e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain GDPD PF03009.17 EGG14212.1 - 5.3e-39 134.5 0.0 4.7e-31 108.4 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EGG14212.1 - 0.0015 18.9 0.5 0.0053 17.2 0.0 2.2 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family MscL PF01741.18 EGG14212.1 - 0.021 15.1 0.1 0.042 14.1 0.1 1.6 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL PPR_2 PF13041.6 EGG14213.1 - 1.1e-16 60.7 0.8 5.5e-09 36.1 0.0 4.0 2 1 2 4 4 4 4 PPR repeat family PPR PF01535.20 EGG14213.1 - 3e-08 33.4 0.6 0.73 10.2 0.0 4.7 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 EGG14213.1 - 3.8e-05 23.1 0.1 0.00047 19.6 0.1 2.4 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EGG14213.1 - 0.00027 20.9 1.0 0.0035 17.4 0.0 2.7 3 0 0 3 3 3 1 Pentatricopeptide repeat domain SdrD_B PF17210.3 EGG14213.1 - 0.013 15.7 1.8 0.026 14.7 1.8 1.4 1 0 0 1 1 1 0 SdrD B-like domain Ten_N PF06484.12 EGG14213.1 - 0.014 15.3 1.7 0.025 14.5 1.7 1.4 1 0 0 1 1 1 0 Teneurin Intracellular Region PPR_1 PF12854.7 EGG14213.1 - 0.024 14.3 2.8 1.7 8.4 0.0 3.9 4 0 0 4 4 4 0 PPR repeat PIP5K PF01504.18 EGG14213.1 - 0.025 13.8 4.4 0.038 13.2 4.4 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF4114 PF13448.6 EGG14213.1 - 0.2 12.5 7.9 16 6.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4114) Kelch_6 PF13964.6 EGG14214.1 - 2.3e-28 97.5 5.2 9.8e-06 25.7 0.0 6.8 5 2 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EGG14214.1 - 6.8e-20 70.8 1.6 0.0022 18.0 0.0 6.8 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EGG14214.1 - 1e-19 69.9 1.7 0.00017 21.1 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 EGG14214.1 - 1.1e-09 38.3 0.0 0.39 11.1 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG14214.1 - 2.6e-06 27.3 2.6 0.051 13.6 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 EGG14214.1 - 2.7e-05 24.0 1.5 1.1 9.4 0.0 5.1 5 0 0 5 5 5 2 Kelch motif WYL_2 PF10902.8 EGG14214.1 - 0.08 13.3 1.0 21 5.6 0.0 3.2 3 0 0 3 3 3 0 WYL_2, Sm-like SH3 beta-barrel fold Miga PF10265.9 EGG14214.1 - 3 6.7 5.9 6.9 5.5 5.9 1.5 1 0 0 1 1 1 0 Mitoguardin SRP-alpha_N PF04086.13 EGG14214.1 - 6.7 6.5 10.3 0.23 11.4 3.9 1.8 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal zf-B_box PF00643.24 EGG14215.1 - 9.8e-07 28.8 5.3 9.8e-07 28.8 5.3 3.7 3 1 0 3 3 3 1 B-box zinc finger zf-RING_6 PF14835.6 EGG14215.1 - 2.6e-06 27.2 3.2 2.6e-06 27.2 3.2 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EGG14215.1 - 5.3e-06 26.5 11.5 5.3e-06 26.5 11.5 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGG14215.1 - 3.3e-05 23.8 6.3 3.3e-05 23.8 6.3 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG14215.1 - 3.4e-05 23.7 6.6 3.4e-05 23.7 6.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGG14215.1 - 6.9e-05 22.6 10.1 6.9e-05 22.6 10.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG14215.1 - 0.00031 21.0 8.6 0.00031 21.0 8.6 2.7 2 0 0 2 2 2 1 Ring finger domain Piezo_RRas_bdg PF12166.8 EGG14215.1 - 0.0007 19.0 5.7 0.0008 18.8 5.7 1.2 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain zf-C3HC4_3 PF13920.6 EGG14215.1 - 0.00075 19.3 6.0 0.00075 19.3 6.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Macoilin PF09726.9 EGG14215.1 - 0.023 13.3 12.0 0.026 13.1 12.0 1.1 1 0 0 1 1 1 0 Macoilin family Prok-RING_4 PF14447.6 EGG14215.1 - 0.026 14.4 8.2 0.026 14.4 8.2 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 CCSAP PF15748.5 EGG14215.1 - 0.059 13.5 9.2 0.1 12.8 9.2 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FapA PF03961.13 EGG14215.1 - 0.12 10.9 5.0 2.4 6.6 0.9 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A Lin-8 PF03353.15 EGG14215.1 - 0.44 10.0 6.6 0.66 9.5 6.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-MIZ PF02891.20 EGG14215.1 - 3.9 7.3 16.6 0.78 9.5 6.9 2.5 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger SPX PF03105.19 EGG14215.1 - 4.8 7.0 18.4 7.9 6.3 18.4 1.4 1 0 0 1 1 1 0 SPX domain Stathmin PF00836.19 EGG14215.1 - 6 6.8 8.5 0.34 10.9 1.8 2.2 3 0 0 3 3 3 0 Stathmin family SNAP PF14938.6 EGG14216.1 - 9.6e-110 366.4 14.1 1.1e-109 366.3 14.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EGG14216.1 - 2.3e-10 40.6 8.6 0.00025 21.3 2.2 3.3 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG14216.1 - 3.6e-06 26.6 7.4 0.21 11.7 0.1 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG14216.1 - 5.4e-06 26.1 21.6 0.13 12.4 0.0 6.5 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGG14216.1 - 4.8e-05 23.8 3.1 0.26 12.2 0.2 4.2 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG14216.1 - 7.8e-05 23.1 5.6 1.6 9.3 0.1 4.4 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG14216.1 - 0.00012 22.5 15.6 1.3 9.8 0.1 6.2 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG14216.1 - 0.00029 20.8 22.5 0.039 14.2 0.2 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG14216.1 - 0.00068 19.8 12.4 0.064 13.5 0.1 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EGG14216.1 - 0.00075 19.0 1.2 0.0011 18.4 1.2 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 EGG14216.1 - 0.00081 19.1 21.2 0.14 12.0 0.4 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat RPN7 PF10602.9 EGG14216.1 - 0.0022 17.7 4.1 0.0047 16.7 1.0 2.3 1 1 1 2 2 2 1 26S proteasome subunit RPN7 Spatacsin_C PF14649.6 EGG14216.1 - 0.0025 17.0 6.6 0.035 13.2 6.6 2.5 1 1 1 2 2 2 1 Spatacsin C-terminus TPR_16 PF13432.6 EGG14216.1 - 0.0038 17.9 4.1 0.078 13.6 0.1 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat DHR-2 PF06920.13 EGG14216.1 - 0.0054 15.4 2.7 0.0069 15.1 1.3 1.8 1 1 0 2 2 2 1 Dock homology region 2 SHNi-TPR PF10516.9 EGG14216.1 - 0.015 14.7 1.1 5.3 6.6 0.0 3.5 3 0 0 3 3 3 0 SHNi-TPR TPR_10 PF13374.6 EGG14216.1 - 0.015 15.1 4.1 7 6.7 0.0 4.7 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGG14216.1 - 0.068 12.9 12.7 1.2 8.9 0.6 4.1 4 1 1 5 5 5 0 TPR repeat NRBF2_MIT PF17169.4 EGG14216.1 - 1.6 9.0 6.8 47 4.3 0.4 3.4 1 1 2 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 MIT PF04212.18 EGG14216.1 - 2 8.5 16.8 10 6.3 1.2 5.1 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain CBS PF00571.28 EGG14217.1 - 4.2e-30 104.0 4.2 4.4e-09 36.7 0.1 4.3 4 0 0 4 4 4 4 CBS domain LAMTOR5 PF16672.5 EGG14217.1 - 0.062 13.2 0.0 4.8 7.2 0.0 2.9 1 1 1 2 2 2 0 Ragulator complex protein LAMTOR5 tRNA-synt_1 PF00133.22 EGG14218.1 - 1e-46 159.4 0.0 2.3e-32 112.0 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGG14218.1 - 1.5e-19 70.0 0.3 1.3e-08 34.0 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGG14218.1 - 2.8e-13 50.1 1.7 6.2e-13 49.0 0.2 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGG14218.1 - 5e-06 26.1 0.0 1.6e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain GAPES4 PF17157.4 EGG14218.1 - 0.019 15.3 0.0 0.39 11.2 0.1 2.6 2 0 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain tRNA-synt_1b PF00579.25 EGG14218.1 - 0.099 11.9 1.3 1.1 8.5 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) DSPc PF00782.20 EGG14219.1 - 6.5e-29 100.4 0.1 6.5e-29 100.4 0.1 3.2 4 0 0 4 4 4 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGG14219.1 - 0.011 15.8 0.0 0.011 15.8 0.0 3.6 3 0 0 3 3 3 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 EGG14219.1 - 0.096 13.0 0.0 0.096 13.0 0.0 2.9 4 0 0 4 4 4 0 Rit1 DUSP-like domain SHR3_chaperone PF08229.11 EGG14220.1 - 0.033 13.2 0.1 0.071 12.1 0.1 1.5 1 0 0 1 1 1 0 ER membrane protein SH3 SR-25 PF10500.9 EGG14220.1 - 0.13 11.9 12.5 0.027 14.1 8.0 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4592 PF15262.6 EGG14220.1 - 0.28 11.8 9.6 0.56 10.9 9.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) GRP PF07172.11 EGG14221.1 - 0.19 12.4 0.2 0.81 10.4 0.0 2.0 2 0 0 2 2 2 0 Glycine rich protein family Presenilin PF01080.17 EGG14221.1 - 0.56 8.9 3.4 0.94 8.2 3.4 1.3 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 EGG14221.1 - 0.58 9.8 2.4 1.3 8.6 2.3 1.5 1 1 0 1 1 1 0 FAM176 family Flocculin PF00624.18 EGG14221.1 - 5.7 7.3 8.8 16 5.9 0.9 2.9 2 0 0 2 2 2 0 Flocculin repeat SUIM_assoc PF16619.5 EGG14222.1 - 0.0014 18.6 4.8 0.027 14.5 0.4 2.5 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 BORG_CEP PF14957.6 EGG14222.1 - 0.13 13.4 6.9 0.099 13.8 4.8 2.0 2 0 0 2 2 2 0 Cdc42 effector WD40 PF00400.32 EGG14222.1 - 0.14 13.1 10.8 28 5.8 0.1 7.0 8 0 0 8 8 8 0 WD domain, G-beta repeat DDHD PF02862.17 EGG14222.1 - 0.14 12.3 2.0 0.14 12.3 0.5 1.7 2 0 0 2 2 2 0 DDHD domain SR-25 PF10500.9 EGG14222.1 - 0.14 11.7 14.3 0.26 10.9 14.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Atrophin-1 PF03154.15 EGG14222.1 - 0.37 9.0 3.8 0.57 8.4 3.8 1.2 1 0 0 1 1 1 0 Atrophin-1 family ANAPC_CDC26 PF10471.9 EGG14222.1 - 0.61 11.0 11.3 2.7 8.9 2.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 TERB2 PF15101.6 EGG14222.1 - 1.2 9.2 6.8 0.14 12.2 1.4 2.0 2 0 0 2 2 2 0 Telomere-associated protein TERB2 RVT_1 PF00078.27 EGG14223.1 - 3.3e-14 52.9 0.0 6.9e-14 51.9 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EGG14223.1 - 0.0009 19.9 0.0 0.0027 18.4 0.0 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Pkinase PF00069.25 EGG14224.1 - 3.8e-60 203.5 0.2 3.8e-60 203.5 0.2 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG14224.1 - 7.9e-40 136.8 0.0 1.3e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG14224.1 - 3.1e-06 26.7 0.8 9e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGG14224.1 - 0.0004 19.3 0.1 0.0004 19.3 0.1 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGG14224.1 - 0.02 14.2 1.4 0.026 13.9 0.3 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG14224.1 - 0.047 13.6 0.0 10 5.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_C1 PF00112.23 EGG14225.1 - 4.3e-49 167.5 6.5 4.3e-49 167.5 6.5 1.9 2 1 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG14225.1 - 6.1e-11 42.6 9.7 7.1e-11 42.4 6.6 2.2 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C39_2 PF13529.6 EGG14225.1 - 0.023 15.2 0.3 0.023 15.2 0.3 2.2 2 0 0 2 2 2 0 Peptidase_C39 like family Cytochrome_cB PF11783.8 EGG14225.1 - 0.074 12.9 0.9 0.2 11.6 0.2 2.0 2 1 0 2 2 2 0 Cytochrome c bacterial RhoGEF PF00621.20 EGG14226.1 - 9.5e-43 146.5 3.7 9.5e-43 146.5 3.7 2.0 2 0 0 2 2 2 1 RhoGEF domain DUF2718 PF10918.8 EGG14226.1 - 0.8 10.2 7.2 0.13 12.8 1.1 2.9 2 1 0 4 4 4 0 Protein of unknown function (DUF2718) Ada3 PF10198.9 EGG14226.1 - 1.6 8.9 7.9 43 4.3 7.7 2.7 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 BRO1 PF03097.18 EGG14228.1 - 6.3e-32 110.8 0.0 1.2e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain INSIG PF07281.12 EGG14228.1 - 0.049 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) BSMAP PF12280.8 EGG14228.1 - 1.2 9.4 10.8 0.32 11.2 3.6 3.0 2 1 0 2 2 2 0 Brain specific membrane anchored protein RNA_pol_Rpc4 PF05132.14 EGG14228.1 - 1.8 9.0 14.9 1.3 9.5 8.0 2.8 2 1 0 2 2 2 0 RNA polymerase III RPC4 SDA1 PF05285.12 EGG14228.1 - 2.7 7.4 22.7 0.012 15.0 8.6 2.1 2 0 0 2 2 2 0 SDA1 SR-25 PF10500.9 EGG14230.1 - 2.1 7.9 5.5 3.2 7.3 5.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_23 PF13476.6 EGG14232.1 - 8.9e-09 36.1 61.1 0.0012 19.4 52.9 4.6 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 EGG14232.1 - 7.1e-07 28.9 24.4 7.1e-07 28.9 24.4 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Metallophos PF00149.28 EGG14232.1 - 1.4e-05 25.7 0.5 1.4e-05 25.7 0.5 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase AAA_29 PF13555.6 EGG14232.1 - 0.0022 17.7 0.0 0.0052 16.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EGG14232.1 - 0.015 15.5 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Coiled PF05710.12 EGG14232.1 - 0.62 10.9 0.0 0.62 10.9 0.0 3.0 2 0 0 2 2 2 0 Coiled coil Cyt-b5 PF00173.28 EGG14233.1 - 9.4e-15 54.5 0.0 2.1e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 EGG14233.1 - 2.1e-13 50.9 2.7 8e-11 42.6 2.7 3.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGG14233.1 - 5e-10 39.6 0.1 1.2e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGG14233.1 - 5.2e-06 26.7 9.2 5.6e-06 26.6 5.4 2.8 2 1 0 2 2 2 1 Ferric reductase NAD binding domain TMEM171 PF15471.6 EGG14233.1 - 9.7 5.1 11.7 0.37 9.7 1.4 2.3 2 0 0 2 2 2 0 Transmembrane protein family 171 PEX11 PF05648.14 EGG14234.1 - 2.8e-54 183.9 5.2 3.2e-54 183.7 5.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Zip PF02535.22 EGG14235.1 - 3.4 6.8 11.5 6.1 6.0 11.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter WD40 PF00400.32 EGG14236.1 - 0.0099 16.7 1.2 4.6 8.3 0.1 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG14236.1 - 0.095 13.0 0.1 0.84 10.0 0.0 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_63 PF03200.16 EGG14237.1 - 6.6e-07 28.5 13.5 2.3e-06 26.6 5.1 4.1 2 2 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Redoxin PF08534.10 EGG14238.1 - 3.2e-14 52.9 0.1 4.3e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGG14238.1 - 0.0016 18.3 0.0 0.0059 16.5 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family DDOST_48kD PF03345.14 EGG14238.1 - 0.059 12.2 0.0 0.076 11.8 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta Ank_2 PF12796.7 EGG14239.1 - 4.9e-34 116.8 11.9 2.4e-06 28.0 0.0 7.1 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14239.1 - 5.1e-30 103.4 7.7 1.8e-05 25.2 0.0 9.9 6 3 4 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14239.1 - 3e-19 67.1 3.7 3.6 8.4 0.0 13.0 14 0 0 14 14 14 5 Ankyrin repeat Ank_5 PF13857.6 EGG14239.1 - 4.5e-19 68.3 11.2 0.52 10.7 0.1 11.9 8 3 6 14 14 14 7 Ankyrin repeats (many copies) Ank PF00023.30 EGG14239.1 - 1e-05 25.7 3.7 29 5.3 0.0 8.7 6 4 1 7 7 7 1 Ankyrin repeat ENTH PF01417.20 EGG14239.1 - 0.031 14.3 5.4 30 4.7 0.1 5.4 5 3 1 6 6 6 0 ENTH domain Ank_2 PF12796.7 EGG14240.1 - 1.1e-37 128.4 11.2 1e-08 35.6 0.0 6.7 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14240.1 - 1.4e-29 102.0 12.7 5.1e-05 23.7 0.0 9.7 8 3 1 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14240.1 - 5.7e-20 69.3 1.9 0.63 10.8 0.0 13.7 15 0 0 15 15 15 3 Ankyrin repeat Ank_5 PF13857.6 EGG14240.1 - 7.7e-19 67.5 9.2 0.21 11.9 0.3 12.0 5 3 7 13 13 13 4 Ankyrin repeats (many copies) DUF5049 PF16468.5 EGG14240.1 - 0.002 18.0 5.6 20 5.2 0.0 7.3 5 3 4 9 9 9 1 Domain of unknown function (DUF5049) Ank PF00023.30 EGG14240.1 - 0.012 16.1 5.8 1.1e+02 3.5 0.3 7.1 6 2 1 7 7 7 0 Ankyrin repeat DUF943 PF06092.12 EGG14240.1 - 0.019 14.6 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) DUF4371 PF14291.6 EGG14240.1 - 0.064 12.9 0.5 9.7 5.8 0.0 3.6 1 1 4 5 5 5 0 Domain of unknown function (DUF4371) HAD PF12710.7 EGG14241.1 - 9.4e-14 52.2 0.0 1.3e-13 51.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG14241.1 - 9.7e-10 39.1 0.0 1.9e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGG14241.1 - 1.3e-05 25.1 5.1 2.1e-05 24.4 0.3 2.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EGG14241.1 - 4e-05 23.1 0.1 0.0006 19.3 0.0 2.2 2 0 0 2 2 2 1 Putative Phosphatase SCAMP PF04144.13 EGG14241.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 SCAMP family adh_short PF00106.25 EGG14242.1 - 6.2e-48 162.8 0.5 8e-48 162.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG14242.1 - 2.2e-32 112.5 0.5 2.7e-32 112.2 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG14242.1 - 8.4e-08 32.3 0.1 1.6e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGG14242.1 - 0.00092 19.1 0.0 0.0014 18.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGG14242.1 - 0.021 14.3 0.0 0.03 13.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family P-II PF00543.22 EGG14243.1 - 0.02 15.5 0.0 0.027 15.1 0.0 1.2 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II LANC_like PF05147.13 EGG14244.1 - 0.028 13.0 2.4 0.035 12.7 2.4 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Glyco_tranf_2_2 PF10111.9 EGG14245.1 - 0.0064 16.0 0.0 0.0071 15.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF1765 PF08578.10 EGG14246.1 - 2.6e-24 86.1 3.0 6e-24 84.9 3.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) SPX PF03105.19 EGG14246.1 - 2.7 7.8 24.5 1 9.2 4.0 2.2 2 0 0 2 2 2 0 SPX domain SOG2 PF10428.9 EGG14247.1 - 7.3 5.7 13.3 7.5 5.6 13.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Suf PF05843.14 EGG14247.1 - 8.9 6.2 15.6 13 5.7 15.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 EGG14247.1 - 9.3 4.9 10.1 13 4.4 10.1 1.3 1 0 0 1 1 1 0 Presenilin Atrophin-1 PF03154.15 EGG14248.1 - 0.00012 20.5 3.0 0.00016 20.1 3.0 1.2 1 0 0 1 1 1 1 Atrophin-1 family MID_MedPIWI PF18296.1 EGG14248.1 - 0.0059 16.4 6.8 0.0082 16.0 6.8 1.1 1 0 0 1 1 1 1 MID domain of medPIWI Med19 PF10278.9 EGG14248.1 - 0.014 15.3 7.3 0.022 14.7 7.3 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Velvet PF11754.8 EGG14248.1 - 0.016 15.2 4.3 0.02 14.8 4.3 1.2 1 0 0 1 1 1 0 Velvet factor Coilin_N PF15862.5 EGG14248.1 - 0.025 14.4 5.1 0.04 13.7 5.1 1.4 1 0 0 1 1 1 0 Coilin N-terminus Ribosomal_60s PF00428.19 EGG14248.1 - 0.029 15.0 0.2 0.051 14.2 0.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3915 PF13054.6 EGG14248.1 - 0.038 14.0 3.3 0.074 13.0 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF3824 PF12868.7 EGG14248.1 - 0.049 14.3 4.4 0.082 13.6 4.4 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF3438 PF11920.8 EGG14248.1 - 0.051 12.8 4.3 0.69 9.1 5.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3438) Cytomega_UL84 PF06284.11 EGG14248.1 - 0.052 12.0 3.2 0.072 11.5 3.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SprA-related PF12118.8 EGG14248.1 - 0.16 11.1 14.3 0.22 10.6 14.3 1.2 1 0 0 1 1 1 0 SprA-related family Itfg2 PF15907.5 EGG14248.1 - 0.24 10.4 2.2 0.32 10.0 2.2 1.1 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 Band_3_cyto PF07565.13 EGG14248.1 - 0.41 10.4 5.6 0.59 9.9 5.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SMYLE_N PF18615.1 EGG14248.1 - 0.42 10.1 5.8 0.68 9.4 5.8 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF4834 PF16118.5 EGG14248.1 - 0.79 10.7 7.4 1.6 9.7 7.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) YqfQ PF14181.6 EGG14248.1 - 0.97 9.6 9.9 1.6 8.9 9.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein Phage_Gp23 PF10669.9 EGG14248.1 - 1.6 9.1 8.0 3.4 8.0 8.0 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Tim54 PF11711.8 EGG14248.1 - 1.9 7.2 10.6 2.7 6.7 10.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 EGG14248.1 - 3.4 7.4 11.1 5 6.9 11.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dicty_REP PF05086.12 EGG14248.1 - 4.5 5.1 12.7 6.2 4.7 12.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Presenilin PF01080.17 EGG14248.1 - 7.2 5.3 12.5 11 4.7 12.5 1.2 1 0 0 1 1 1 0 Presenilin Methyltransf_23 PF13489.6 EGG14249.1 - 3.1e-17 62.9 0.0 8.8e-17 61.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG14249.1 - 1e-13 51.9 0.0 1e-13 51.9 0.0 3.4 3 2 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG14249.1 - 1.4e-12 48.2 0.0 3.2e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG14249.1 - 1.5e-12 47.5 2.5 2.5e-12 46.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG14249.1 - 5.6e-10 39.7 0.0 2.1e-09 37.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG14249.1 - 0.00014 21.3 0.0 0.0007 19.0 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EGG14249.1 - 0.00042 19.7 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EGG14249.1 - 0.0012 18.4 0.0 0.0041 16.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EGG14249.1 - 0.0023 17.4 0.0 0.0023 17.4 0.0 3.0 3 1 0 3 3 3 1 Putative methyltransferase Met_10 PF02475.16 EGG14249.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_24 PF13578.6 EGG14249.1 - 0.057 14.4 0.0 0.2 12.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Qua1 PF16274.5 EGG14249.1 - 0.42 10.5 0.1 0.42 10.5 0.1 2.8 3 0 0 3 3 2 0 Qua1 domain GRP PF07172.11 EGG14249.1 - 6.5 7.5 15.6 5.3 7.8 1.4 2.9 3 0 0 3 3 3 0 Glycine rich protein family DUF4038 PF13204.6 EGG14250.1 - 0.089 12.4 0.0 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4038) Asp PF00026.23 EGG14251.1 - 1.4e-35 123.3 1.0 7.9e-35 120.8 1.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGG14251.1 - 4.6e-13 49.2 0.0 1.1e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal ECSCR PF15820.5 EGG14251.1 - 0.059 13.2 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator YebO PF13974.6 EGG14251.1 - 0.3 11.2 1.8 0.55 10.3 1.8 1.4 1 0 0 1 1 1 0 YebO-like protein Methyltransf_31 PF13847.6 EGG14252.1 - 3.2e-11 43.3 1.1 5.7e-11 42.4 1.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG14252.1 - 2e-10 41.2 0.0 5.6e-10 39.8 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG14252.1 - 1.2e-09 38.7 0.1 3.9e-09 37.0 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EGG14252.1 - 4.3e-09 36.1 0.0 5.1e-09 35.8 0.0 1.2 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EGG14252.1 - 3.5e-08 34.1 1.6 1.3e-07 32.2 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGG14252.1 - 2.2e-07 30.9 0.2 5.2e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG14252.1 - 1.1e-06 28.6 0.0 1.4e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGG14252.1 - 1.2e-05 25.3 0.9 5.4e-05 23.2 0.9 1.9 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EGG14252.1 - 2.8e-05 23.8 0.0 6.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DOT1 PF08123.13 EGG14252.1 - 7.5e-05 22.4 1.1 0.00027 20.5 1.1 1.8 1 1 0 1 1 1 1 Histone methylation protein DOT1 UPF0020 PF01170.18 EGG14252.1 - 9.5e-05 22.2 0.0 0.0037 17.0 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 EGG14252.1 - 0.00016 21.2 1.3 0.00019 20.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EGG14252.1 - 0.0002 20.9 0.5 0.00065 19.2 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 EGG14252.1 - 0.00026 20.8 0.1 0.001 18.9 0.0 1.9 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EGG14252.1 - 0.00027 20.5 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EGG14252.1 - 0.00043 19.7 0.1 0.00079 18.8 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 EGG14252.1 - 0.0011 18.6 0.6 0.0025 17.4 0.1 1.8 1 1 1 2 2 2 1 RNA cap guanine-N2 methyltransferase N6_N4_Mtase PF01555.18 EGG14252.1 - 0.0017 18.1 2.2 0.0055 16.4 0.0 2.2 2 1 0 2 2 2 1 DNA methylase ADH_zinc_N PF00107.26 EGG14252.1 - 0.0029 17.6 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_8 PF05148.15 EGG14252.1 - 0.035 13.9 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase Ank_2 PF12796.7 EGG14253.1 - 3.6e-21 75.5 4.4 5.7e-05 23.6 0.0 5.8 4 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14253.1 - 5.7e-16 58.7 0.3 0.0011 19.5 0.0 8.3 8 1 1 9 9 9 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14253.1 - 4.5e-07 29.7 0.9 10 7.1 0.0 8.8 10 1 1 11 11 11 1 Ankyrin repeat Ank_5 PF13857.6 EGG14253.1 - 0.0003 21.0 0.2 15 6.0 0.0 6.1 5 2 3 8 8 8 1 Ankyrin repeats (many copies) OTU PF02338.19 EGG14254.1 - 7.2e-17 62.1 0.4 1.9e-16 60.7 0.1 1.8 1 1 1 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGG14254.1 - 1e-06 28.4 0.4 0.02 14.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain UBA PF00627.31 EGG14254.1 - 0.0091 15.9 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 EGG14254.1 - 0.044 13.5 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 CUE domain CTK3 PF12243.8 EGG14254.1 - 0.16 12.0 0.0 0.16 12.0 0.0 3.1 4 0 0 4 4 4 0 CTD kinase subunit gamma CTK3 BLOC1S3 PF15753.5 EGG14254.1 - 0.18 12.0 8.3 0.19 11.8 5.8 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF4820 PF16091.5 EGG14254.1 - 2.7 7.3 6.5 8.1 5.7 6.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NPR3 PF03666.13 EGG14254.1 - 3.4 6.4 9.4 7.1 5.3 9.4 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 EGG14254.1 - 5.1 5.8 8.7 9.9 4.8 8.7 1.4 1 0 0 1 1 1 0 Presenilin Peptidase_C92 PF05708.12 EGG14255.1 - 9.5e-06 25.8 0.3 0.00015 21.9 0.3 2.5 1 1 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Beta-lactamase2 PF13354.6 EGG14256.1 - 0.034 13.8 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase enzyme family DUF2058 PF09831.9 EGG14256.1 - 2.7 8.1 4.1 4.9 7.3 4.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Epimerase PF01370.21 EGG14257.1 - 1.6e-10 40.9 0.1 2.1e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGG14257.1 - 6.3e-10 39.2 0.0 1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGG14257.1 - 4.4e-07 29.7 0.8 0.00012 21.7 0.1 2.1 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.19 EGG14257.1 - 1.3e-05 24.3 0.0 0.022 13.8 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGG14257.1 - 5.9e-05 22.6 0.0 0.0058 16.1 0.1 2.6 2 1 1 3 3 3 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 EGG14257.1 - 0.00012 22.3 0.1 0.00021 21.5 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 EGG14257.1 - 0.00028 21.4 0.1 0.00083 19.9 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EGG14257.1 - 0.00032 20.9 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 EGG14257.1 - 0.00063 19.3 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 EGG14257.1 - 0.0017 18.3 0.5 0.0056 16.6 0.1 2.0 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EGG14257.1 - 0.0046 16.1 0.1 0.0073 15.4 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Gsf2 PF11055.8 EGG14257.1 - 0.017 13.9 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Glucose signalling factor 2 DapB_N PF01113.20 EGG14257.1 - 0.034 14.3 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 EGG14257.1 - 0.056 13.5 0.1 0.094 12.8 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.16 EGG14257.1 - 0.084 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EGG14257.1 - 0.11 11.8 0.2 0.18 11.1 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.24 EGG14257.1 - 0.18 12.3 0.4 1.3 9.5 0.3 2.3 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Arm PF00514.23 EGG14258.1 - 1.8e-86 281.9 19.0 1.7e-12 46.9 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGG14258.1 - 1.4e-25 89.3 3.5 1.9e-10 41.0 0.0 5.9 4 2 2 6 6 6 4 HEAT-like repeat IBB PF01749.20 EGG14258.1 - 9.7e-17 61.2 1.7 3e-16 59.6 1.7 1.9 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 EGG14258.1 - 1e-16 61.1 0.0 9.9e-06 25.9 0.0 4.4 1 1 4 5 5 5 4 HEAT repeats Arm_3 PF16186.5 EGG14258.1 - 4.8e-15 54.9 0.0 2.3e-14 52.7 0.2 2.0 2 0 0 2 2 2 1 Atypical Arm repeat HEAT PF02985.22 EGG14258.1 - 4.4e-11 42.1 6.9 0.00047 20.2 0.0 7.6 9 0 0 9 9 9 1 HEAT repeat Arm_2 PF04826.13 EGG14258.1 - 2e-07 30.8 0.1 0.0025 17.3 0.3 2.8 2 1 1 3 3 3 3 Armadillo-like HEAT_PBS PF03130.16 EGG14258.1 - 3e-05 24.3 1.4 1.3 9.9 0.0 5.9 6 0 0 6 6 5 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 EGG14258.1 - 9.9e-05 22.4 0.1 4.1 7.5 0.0 4.1 3 1 2 5 5 5 3 V-ATPase subunit H Adaptin_N PF01602.20 EGG14258.1 - 0.00022 19.9 0.0 0.073 11.6 0.0 2.7 1 1 1 2 2 2 2 Adaptin N terminal region RICTOR_V PF14668.6 EGG14258.1 - 0.00026 21.2 0.9 6.2 7.1 0.1 4.5 4 1 2 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 CTNNBL PF08216.11 EGG14258.1 - 0.0092 16.1 0.3 11 6.3 0.0 4.3 4 1 1 5 5 5 1 Catenin-beta-like, Arm-motif containing nuclear Mo25 PF08569.11 EGG14258.1 - 0.028 13.8 0.0 0.11 11.8 0.0 1.9 2 1 0 2 2 2 0 Mo25-like SH2_2 PF14633.6 EGG14259.1 - 1.5e-61 207.5 0.9 1.5e-61 207.5 0.9 2.2 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 EGG14259.1 - 2.1e-21 76.2 0.1 4.5e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EGG14259.1 - 2.5e-20 72.8 0.0 6e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 EGG14259.1 - 3.8e-15 56.3 1.8 1.7e-14 54.2 1.8 2.1 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.24 EGG14259.1 - 3.8e-07 30.1 0.0 3e-05 24.0 0.0 2.8 2 0 0 2 2 2 1 SH2 domain HHH_9 PF17674.1 EGG14259.1 - 1.2e-06 29.3 1.3 1.9e-05 25.5 0.1 3.4 2 0 0 2 2 2 1 HHH domain Tex_N PF09371.10 EGG14259.1 - 0.0016 18.1 0.0 0.054 13.2 0.0 2.4 2 0 0 2 2 2 1 Tex-like protein N-terminal domain ParBc_2 PF08857.11 EGG14262.1 - 1.3e-60 204.2 0.0 1.9e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Putative ParB-like nuclease FANCF PF11107.8 EGG14262.1 - 0.092 11.9 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) Myb_DNA-binding PF00249.31 EGG14263.1 - 1.8e-28 98.5 8.3 1.1e-13 51.2 0.8 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG14263.1 - 2.4e-25 88.6 3.1 2.9e-13 49.9 0.1 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGG14263.1 - 0.00015 22.1 12.4 0.0097 16.3 0.3 4.0 3 1 0 4 4 4 2 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 EGG14263.1 - 0.0014 18.6 0.3 0.97 9.5 0.2 3.0 2 1 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EGG14263.1 - 0.064 13.5 6.7 3.3 8.0 0.0 3.8 2 1 2 4 4 4 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 EGG14263.1 - 0.31 11.2 7.9 28 4.9 0.9 3.7 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EGG14263.1 - 0.5 10.7 12.1 2.1 8.7 0.1 4.9 4 1 1 5 5 5 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Dehydrin PF00257.19 EGG14263.1 - 0.92 10.0 4.2 2.9 8.4 4.2 1.9 1 0 0 1 1 1 0 Dehydrin SR-25 PF10500.9 EGG14263.1 - 2.3 7.8 10.7 0.084 12.5 4.0 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein YEATS PF03366.16 EGG14264.1 - 7e-29 99.6 0.0 1.3e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 YEATS family MADF_DNA_bdg PF10545.9 EGG14264.1 - 0.017 15.5 2.5 0.082 13.2 1.6 2.4 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DHR10 PF18595.1 EGG14264.1 - 0.064 13.3 14.4 0.093 12.8 13.9 1.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain SUIM_assoc PF16619.5 EGG14264.1 - 0.13 12.4 8.8 0.32 11.1 8.8 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF724 PF05266.14 EGG14264.1 - 2.1 8.1 10.6 3.1 7.6 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Vir_act_alpha_C PF10400.9 EGG14264.1 - 2.6 8.8 5.3 6.6 7.5 5.2 1.7 1 1 1 2 2 2 0 Virulence activator alpha C-term V_ATPase_I PF01496.19 EGG14264.1 - 3.8 5.3 10.9 4.8 5.0 10.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TGT PF01702.18 EGG14265.1 - 2e-74 250.8 0.2 2.9e-74 250.3 0.2 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PsaF PF17550.2 EGG14265.1 - 0.028 13.9 0.1 0.11 12.0 0.0 1.9 1 1 0 1 1 1 0 Family of unknown function CTD_bind PF04818.13 EGG14267.1 - 3.1e-09 37.5 0.7 2e-08 34.9 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase II-binding domain. zf-C2H2_4 PF13894.6 EGG14267.1 - 0.055 14.3 6.0 0.18 12.7 0.9 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger CFIA_Pcf11 PF11526.8 EGG14267.1 - 0.096 13.2 0.3 0.096 13.2 0.3 5.4 4 1 0 5 5 5 0 Subunit of cleavage factor IA Pcf11 GPS PF01825.21 EGG14267.1 - 0.12 12.9 0.3 0.32 11.5 0.3 1.7 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif CBM49 PF09478.10 EGG14269.1 - 1.2e-12 47.9 0.5 1.9e-12 47.3 0.5 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF3439 PF11921.8 EGG14269.1 - 4.2 7.3 15.7 2.8 7.9 11.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Med3 PF11593.8 EGG14269.1 - 4.4 6.4 12.1 5.7 6.0 12.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CBM49 PF09478.10 EGG14270.1 - 2.9e-09 37.1 1.0 5.8e-09 36.1 1.0 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM49 PF09478.10 EGG14271.1 - 7e-09 35.9 1.1 1.5e-08 34.9 1.1 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 XLF PF09302.11 EGG14272.1 - 0.11 12.6 16.7 0.2 11.8 16.7 1.4 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF1465 PF07323.12 EGG14272.1 - 0.91 9.3 14.3 0.25 11.2 1.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1465) Hypoth_Ymh PF09509.10 EGG14272.1 - 1.3 9.0 8.7 0.76 9.7 0.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (Hypoth_ymh) Dynactin_p22 PF07426.11 EGG14272.1 - 1.6 8.5 24.4 3.2 7.6 24.4 1.5 1 1 0 1 1 1 0 Dynactin subunit p22 DUF4094 PF13334.6 EGG14272.1 - 2.5 8.6 14.0 0.91 10.0 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) Med30 PF11315.8 EGG14272.1 - 3.8 7.7 24.3 2.3 8.4 13.6 2.2 1 1 1 2 2 2 0 Mediator complex subunit 30 COX6B PF02297.17 EGG14273.1 - 0.007 16.6 8.0 0.011 16.0 8.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EGG14273.1 - 0.016 15.2 8.1 0.026 14.6 8.1 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DAGK_cat PF00781.24 EGG14274.1 - 4.1e-27 94.3 0.0 9e-27 93.2 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SelK_SelG PF10961.8 EGG14274.1 - 0.45 11.2 3.3 0.47 11.1 0.1 2.5 2 0 0 2 2 2 0 Selenoprotein SelK_SelG ALMT PF11744.8 EGG14274.1 - 1.3 7.7 17.5 3.6 6.3 10.5 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter Menin PF05053.13 EGG14274.1 - 2.5 6.3 14.8 4.4 5.5 14.8 1.3 1 0 0 1 1 1 0 Menin Hydrolase_4 PF12146.8 EGG14275.1 - 8.7e-08 31.7 0.0 4.6e-06 26.1 0.0 2.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 SAM_1 PF00536.30 EGG14275.1 - 2.3e-07 31.2 0.0 1.2e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGG14275.1 - 2.4e-05 24.3 0.0 6.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Abhydrolase_1 PF00561.20 EGG14275.1 - 2.6e-05 24.0 0.0 0.00035 20.3 0.0 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG14275.1 - 0.0025 17.3 0.0 0.026 14.0 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 EGG14275.1 - 0.0041 16.8 0.0 0.0095 15.6 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 EGG14275.1 - 0.0094 15.7 0.0 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 EGG14275.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase UQ_con PF00179.26 EGG14276.1 - 5.1e-40 136.4 0.1 1e-39 135.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Dicty_REP PF05086.12 EGG14276.1 - 2.7 5.8 17.9 3.6 5.4 17.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF913 PF06025.12 EGG14276.1 - 8.4 5.2 10.6 12 4.7 10.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) YL1_C PF08265.11 EGG14277.1 - 1.2e-11 44.1 3.9 1.2e-11 44.1 3.9 2.1 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain DUF365 PF04033.12 EGG14278.1 - 0.0038 17.5 0.9 0.0047 17.2 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF365) DUF4300 PF14133.6 EGG14278.1 - 0.022 14.5 0.2 0.025 14.3 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) DUF3673 PF12425.8 EGG14278.1 - 0.05 13.5 5.0 0.11 12.5 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3673) Prenylcys_lyase PF07156.14 EGG14278.1 - 0.074 12.1 0.0 0.089 11.9 0.0 1.0 1 0 0 1 1 1 0 Prenylcysteine lyase FH2 PF02181.23 EGG14279.1 - 6.1e-76 255.9 5.2 6.1e-76 255.9 5.2 3.3 3 0 0 3 3 3 1 Formin Homology 2 Domain FNIP PF05725.12 EGG14280.1 - 7.5e-37 125.2 1.4 4.1e-10 39.7 0.0 10.1 7 2 3 11 11 11 7 FNIP Repeat LRR_4 PF12799.7 EGG14280.1 - 0.00095 19.5 10.9 3.6 8.2 0.5 6.6 4 3 3 7 7 7 2 Leucine Rich repeats (2 copies) MTABC_N PF16185.5 EGG14281.1 - 0.014 15.0 0.9 0.014 15.0 0.9 1.4 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region FixH PF05751.11 EGG14281.1 - 1.5 8.9 3.7 3.9 7.5 0.5 2.2 2 0 0 2 2 2 0 FixH Motile_Sperm PF00635.26 EGG14282.1 - 1.1e-24 86.3 0.5 3e-24 85.0 0.5 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Lipase_GDSL PF00657.22 EGG14282.1 - 2.8e-13 50.3 0.1 2.8e-13 50.3 0.1 3.0 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EGG14282.1 - 0.00082 19.8 0.2 0.024 15.0 0.2 2.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family LMBR1 PF04791.16 EGG14282.1 - 0.0031 16.5 4.8 0.0046 15.9 4.8 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein LAP1C PF05609.12 EGG14282.1 - 0.038 13.1 11.9 0.055 12.6 11.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3533 PF12051.8 EGG14282.1 - 0.067 12.1 2.8 0.13 11.1 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) HALZ PF02183.18 EGG14282.1 - 0.089 13.0 2.7 0.2 11.9 2.7 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper OmpH PF03938.14 EGG14282.1 - 0.16 12.3 10.7 0.39 11.1 5.5 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF5320 PF17253.2 EGG14282.1 - 0.27 12.3 1.1 1.1 10.4 0.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) SOGA PF11365.8 EGG14282.1 - 0.27 12.4 4.6 0.88 10.7 4.6 1.9 1 0 0 1 1 1 0 Protein SOGA Cnn_1N PF07989.11 EGG14282.1 - 0.65 10.2 7.3 0.11 12.6 2.1 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 RR_TM4-6 PF06459.12 EGG14282.1 - 0.82 9.5 10.1 1.3 8.8 10.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tropomyosin_1 PF12718.7 EGG14282.1 - 0.94 9.6 10.6 0.95 9.6 7.5 2.1 2 0 0 2 2 2 0 Tropomyosin like ABC_tran PF00005.27 EGG14283.1 - 3e-35 121.7 0.0 9.2e-35 120.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGG14283.1 - 3.1e-34 118.9 8.5 4.4e-34 118.4 8.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGG14283.1 - 4e-08 33.0 0.0 3.4e-07 29.9 0.0 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGG14283.1 - 8.7e-05 22.4 0.7 0.0047 16.7 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EGG14283.1 - 0.0023 17.6 0.1 0.007 16.1 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGG14283.1 - 0.003 17.8 0.1 0.014 15.7 0.0 2.1 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 EGG14283.1 - 0.0069 15.6 0.0 0.0069 15.6 0.0 2.5 3 0 0 3 3 3 1 G-protein alpha subunit AAA_18 PF13238.6 EGG14283.1 - 0.0071 16.9 0.0 0.028 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGG14283.1 - 0.013 15.4 0.0 0.045 13.7 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EGG14283.1 - 0.014 15.8 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 EGG14283.1 - 0.026 14.6 1.1 0.071 13.2 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 EGG14283.1 - 0.029 14.2 0.4 0.066 13.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 EGG14283.1 - 0.056 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF1673 PF07895.11 EGG14283.1 - 0.2 11.4 2.2 9.7 5.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) AAA_28 PF13521.6 EGG14283.1 - 0.34 11.2 2.4 0.85 9.8 0.2 2.4 2 1 0 3 3 3 0 AAA domain HIP1_clath_bdg PF16515.5 EGG14283.1 - 0.7 10.5 4.0 0.84 10.3 0.1 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Macoilin PF09726.9 EGG14283.1 - 0.89 8.0 7.6 1.6 7.2 7.6 1.4 1 0 0 1 1 1 0 Macoilin family L51_S25_CI-B8 PF05047.16 EGG14284.1 - 0.1 12.5 0.4 0.32 11.0 0.4 1.9 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain adh_short_C2 PF13561.6 EGG14285.1 - 2.5e-49 167.9 0.1 3.5e-49 167.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG14285.1 - 4.6e-47 160.0 0.1 6.5e-47 159.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG14285.1 - 2.3e-09 37.4 0.0 4.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG14285.1 - 8.1e-05 22.2 0.0 0.00021 20.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGG14285.1 - 0.0092 15.1 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGG14285.1 - 0.017 14.2 0.3 0.028 13.4 0.3 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGG14285.1 - 0.048 13.1 0.1 1.1 8.5 0.1 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 EGG14285.1 - 0.083 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.32 EGG14286.1 - 1.2e-44 149.4 18.4 1e-08 35.7 0.2 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG14286.1 - 5.2e-11 42.7 0.5 0.011 16.0 0.0 5.0 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG14286.1 - 1.6e-07 30.4 2.9 0.085 11.5 0.0 5.2 1 1 2 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGG14286.1 - 1.5e-06 27.4 0.5 0.2 10.6 0.0 4.5 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EGG14286.1 - 0.00035 19.2 0.1 0.61 8.6 0.0 2.8 3 0 0 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EGG14286.1 - 0.0013 17.6 0.7 0.91 8.2 0.0 4.0 2 1 1 4 4 4 2 Nup133 N terminal like PALB2_WD40 PF16756.5 EGG14286.1 - 0.0029 16.6 2.0 0.028 13.3 0.1 2.8 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Peptidase_S8 PF00082.22 EGG14286.1 - 0.016 14.5 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 Subtilase family Ank_2 PF12796.7 EGG14287.1 - 3.2e-19 69.3 21.2 8.1e-06 26.3 0.1 7.9 4 2 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14287.1 - 2e-12 47.4 17.4 0.35 11.5 0.0 10.1 9 2 0 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14287.1 - 4.5e-10 38.9 15.7 1.5 9.6 0.0 11.7 12 1 1 13 13 13 1 Ankyrin repeat Ank_5 PF13857.6 EGG14287.1 - 6.8e-07 29.4 5.6 0.55 10.6 0.0 7.8 7 3 2 9 9 9 1 Ankyrin repeats (many copies) Ank PF00023.30 EGG14287.1 - 0.11 13.0 6.6 1.5e+02 3.1 0.0 7.0 6 2 0 6 6 6 0 Ankyrin repeat Phage_term_sma PF07141.11 EGG14287.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit ATP-cone PF03477.16 EGG14287.1 - 0.17 12.5 1.2 1.3 9.7 0.0 2.8 3 0 0 3 3 3 0 ATP cone domain Cytochrom_C1 PF02167.15 EGG14288.1 - 7.4e-91 303.7 0.0 8.7e-91 303.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EGG14288.1 - 0.0017 18.6 0.0 0.0041 17.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EGG14288.1 - 0.13 13.4 0.8 0.37 12.0 0.2 1.9 2 1 0 2 2 2 0 Cytochrome c Spectrin PF00435.21 EGG14289.1 - 0.75 10.3 8.3 0.12 12.8 4.1 1.8 2 0 0 2 2 2 0 Spectrin repeat p450 PF00067.22 EGG14290.1 - 3.6e-13 49.1 0.1 4.8e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_9 PF13527.7 EGG14292.1 - 0.00011 22.3 0.1 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG14292.1 - 0.052 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG14292.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF826 PF05696.11 EGG14293.1 - 0.02 15.0 2.3 0.088 12.9 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF826) NAD_Gly3P_dh_N PF01210.23 EGG14293.1 - 0.047 13.7 0.2 0.07 13.1 0.2 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus EcsC PF12787.7 EGG14293.1 - 0.09 12.4 0.5 0.12 12.0 0.5 1.2 1 0 0 1 1 1 0 EcsC protein family Sporozoite_P67 PF05642.11 EGG14293.1 - 0.13 10.3 4.5 0.15 10.1 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4611 PF15387.6 EGG14293.1 - 1.4 9.2 7.2 4.1 7.7 7.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) EGF_2 PF07974.13 EGG14294.1 - 3.7e-05 24.0 11.2 9e-05 22.8 11.2 1.7 1 0 0 1 1 1 1 EGF-like domain fn3 PF00041.21 EGG14294.1 - 0.0066 16.8 3.0 6.4 7.2 0.1 3.3 3 0 0 3 3 3 2 Fibronectin type III domain Lum_binding PF00677.17 EGG14294.1 - 0.079 12.9 0.5 0.31 11.0 0.2 2.2 1 1 0 1 1 1 0 Lumazine binding domain Str_synth PF03088.16 EGG14295.1 - 2.7e-19 69.1 0.1 3.4e-18 65.5 0.0 2.6 2 1 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 EGG14295.1 - 5.5e-14 52.3 0.0 8e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EGG14295.1 - 0.00036 20.4 0.6 0.99 9.6 0.1 3.2 3 0 0 3 3 3 2 NHL repeat Arylesterase PF01731.20 EGG14295.1 - 0.0037 17.4 0.0 0.012 15.8 0.0 1.9 2 0 0 2 2 2 1 Arylesterase Ldh_1_C PF02866.18 EGG14296.1 - 3.4e-35 121.5 0.0 5.2e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGG14296.1 - 6.2e-30 104.1 0.0 9.1e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Cpn60_TCP1 PF00118.24 EGG14297.1 - 8.8e-99 331.3 4.7 8.8e-99 331.3 4.7 2.4 3 1 0 3 3 3 1 TCP-1/cpn60 chaperonin family ATG16 PF08614.11 EGG14297.1 - 0.0035 17.6 16.3 0.0035 17.6 16.3 5.4 1 1 1 3 3 3 1 Autophagy protein 16 (ATG16) FR47 PF08445.10 EGG14299.1 - 9.8e-12 44.7 0.0 1.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Gly_acyl_tr_C PF08444.10 EGG14299.1 - 0.00047 20.3 0.0 0.0013 18.9 0.0 1.7 2 0 0 2 2 2 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_3 PF13302.7 EGG14299.1 - 0.0014 19.3 0.0 0.0022 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG14299.1 - 0.0023 18.2 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG14299.1 - 0.019 15.4 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG14299.1 - 0.045 13.7 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.15 EGG14300.1 - 0.0002 21.4 0.4 0.0003 20.8 0.4 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Helicase_C PF00271.31 EGG14301.1 - 1.9e-19 70.0 0.0 1.9e-19 70.0 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.31 EGG14301.1 - 2.2e-07 30.9 0.0 5.4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 EGG14302.1 - 1.7e-13 50.7 2.3 1.7e-13 50.7 2.3 4.6 4 1 0 4 4 4 1 HSA Rab5ip PF07019.12 EGG14303.1 - 2e-15 57.1 9.7 2.7e-15 56.7 9.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF2298 PF10060.9 EGG14303.1 - 0.00099 17.9 0.4 0.0012 17.7 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) SLC12 PF03522.15 EGG14304.1 - 0.1 11.6 12.8 0.13 11.3 12.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Dapper PF15268.6 EGG14306.1 - 4.8 5.9 24.2 5.9 5.6 24.2 1.2 1 0 0 1 1 1 0 Dapper Utp14 PF04615.13 EGG14306.1 - 8 4.9 22.8 9.6 4.6 22.8 1.1 1 0 0 1 1 1 0 Utp14 protein gag-asp_proteas PF13975.6 EGG14307.1 - 0.18 12.4 0.0 0.26 11.9 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Patatin PF01734.22 EGG14308.1 - 0.0036 17.5 0.0 0.08 13.1 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.22 EGG14309.1 - 1.7e-16 61.0 0.0 3.9e-16 59.8 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1748 PF08520.10 EGG14309.1 - 0.13 12.2 0.1 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1748) YajC PF02699.15 EGG14310.1 - 0.1 12.5 0.1 7.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit UQ_con PF00179.26 EGG14311.1 - 1.4e-07 31.2 0.0 4.8e-07 29.5 0.0 1.6 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme DUF572 PF04502.13 EGG14312.1 - 0.94 9.0 33.3 1.3 8.6 33.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_L14e PF01929.17 EGG14313.1 - 1.6e-21 76.6 1.0 3.2e-21 75.6 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L14 TPR_14 PF13428.6 EGG14313.1 - 7.8e-13 48.1 4.0 0.86 10.6 0.0 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat Suf PF05843.14 EGG14313.1 - 7.8e-09 35.9 28.9 0.0066 16.5 0.1 6.4 4 1 0 5 5 5 3 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 EGG14313.1 - 2.6e-07 30.7 20.2 1 9.4 0.3 7.8 6 2 1 7 7 7 4 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 EGG14313.1 - 3.5e-07 29.8 7.5 0.15 12.3 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG14313.1 - 5e-06 26.9 0.0 2.6 8.6 0.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG14313.1 - 0.00014 21.8 6.6 0.041 14.1 0.1 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG14313.1 - 0.004 17.8 2.8 3.4 8.4 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat SF3A3 PF16837.5 EGG14313.1 - 0.0095 16.4 9.3 0.025 15.1 0.2 4.5 4 0 0 4 4 4 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 TPR_12 PF13424.6 EGG14313.1 - 0.012 15.9 9.6 0.14 12.4 0.0 4.2 4 1 0 4 4 3 0 Tetratricopeptide repeat KOW PF00467.29 EGG14313.1 - 0.013 15.5 0.1 0.026 14.5 0.1 1.6 1 0 0 1 1 1 0 KOW motif RPN7 PF10602.9 EGG14313.1 - 0.033 13.9 5.4 12 5.5 0.8 4.2 4 0 0 4 4 4 0 26S proteasome subunit RPN7 TPR_1 PF00515.28 EGG14313.1 - 0.034 14.0 1.1 2.1 8.3 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG14313.1 - 0.054 13.5 2.0 0.25 11.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGG14313.1 - 1.1 9.2 3.3 3.8 7.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.16 EGG14313.1 - 2.2 8.3 4.8 13 5.9 0.0 4.4 4 0 0 4 4 4 0 HAT (Half-A-TPR) repeat COX6C PF02937.15 EGG14314.1 - 0.045 13.9 0.0 0.056 13.6 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Aldo_ket_red PF00248.21 EGG14315.1 - 9.1e-48 162.9 0.2 4.1e-36 124.7 0.1 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family HAD_2 PF13419.6 EGG14315.1 - 0.1 12.7 0.2 2.9 7.9 0.0 2.3 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase EamA PF00892.20 EGG14316.1 - 1.2e-12 48.2 33.9 6e-08 32.9 9.6 3.3 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 EGG14316.1 - 8.4e-09 35.3 16.4 1.3e-08 34.8 16.4 1.2 1 0 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 EGG14316.1 - 7.1e-05 22.2 16.0 7.1e-05 22.2 16.0 2.0 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 EGG14316.1 - 0.0003 19.8 9.7 0.0003 19.8 9.7 2.5 2 1 0 3 3 3 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 EGG14316.1 - 0.082 12.2 15.2 0.0079 15.6 9.5 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family Cadherin_C_2 PF16492.5 EGG14316.1 - 0.85 10.4 5.5 1.8 9.4 0.0 3.1 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal GWT1 PF06423.12 EGG14316.1 - 0.86 9.7 11.0 25 5.0 0.0 4.0 2 1 2 4 4 4 0 GWT1 Ribosomal_L26 PF16906.5 EGG14317.1 - 0.046 14.2 0.0 0.16 12.4 0.0 1.9 1 1 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal EamA PF00892.20 EGG14318.1 - 7.2e-10 39.2 36.3 7.9e-06 26.1 13.4 3.0 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 EGG14318.1 - 2e-06 27.5 17.7 2e-06 27.5 17.7 1.9 2 0 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 EGG14318.1 - 0.001 18.4 7.9 0.001 18.4 7.9 2.6 2 1 1 3 3 3 1 Purine nucleobase transmembrane transport SCF PF02404.15 EGG14318.1 - 0.0043 16.4 0.5 0.038 13.3 0.2 2.1 2 0 0 2 2 2 1 Stem cell factor Phage_Gp23 PF10669.9 EGG14318.1 - 0.064 13.6 1.0 0.19 12.1 0.1 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) OAD_gamma PF04277.13 EGG14318.1 - 0.32 11.6 2.8 2.1 9.0 0.2 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF4834 PF16118.5 EGG14318.1 - 1.9 9.5 7.3 0.62 11.1 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) FAD_binding_3 PF01494.19 EGG14319.1 - 3.3e-21 75.9 0.0 4.6e-10 39.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 EGG14319.1 - 7.6e-09 35.0 1.2 1.2e-08 34.4 0.1 1.8 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 EGG14319.1 - 1.2e-05 24.6 0.1 0.004 16.3 0.5 2.9 2 1 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EGG14319.1 - 1.2e-05 24.4 0.0 0.011 14.6 0.0 3.0 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 EGG14319.1 - 0.00014 21.2 0.1 0.046 12.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGG14319.1 - 0.001 18.7 0.1 0.0023 17.6 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG14319.1 - 0.013 14.2 0.3 0.074 11.7 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 EGG14319.1 - 0.019 15.5 0.1 0.11 13.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG14319.1 - 0.044 14.0 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGG14319.1 - 0.17 11.1 0.2 0.44 9.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Skp1 PF01466.19 EGG14320.1 - 1.6e-25 88.9 1.6 4.8e-25 87.4 0.6 2.1 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EGG14320.1 - 2.3e-25 88.5 0.6 4.7e-25 87.6 0.6 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain p450 PF00067.22 EGG14321.1 - 3.2e-95 319.6 0.0 3.6e-95 319.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cnd1 PF12717.7 EGG14321.1 - 0.15 12.1 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 SpoU_methylase PF00588.19 EGG14322.1 - 2.7e-27 95.7 0.0 7.5e-27 94.2 0.0 1.9 1 0 0 1 1 1 1 SpoU rRNA Methylase family Bromodomain PF00439.25 EGG14322.1 - 1.9e-11 43.8 0.0 7.4e-11 42.0 0.0 2.1 1 0 0 1 1 1 1 Bromodomain DUF2719 PF10891.8 EGG14322.1 - 0.0083 16.0 0.2 0.041 13.8 0.2 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2719) NOA36 PF06524.12 EGG14322.1 - 4.2 6.6 7.9 12 5.1 7.9 1.7 1 0 0 1 1 1 0 NOA36 protein Cellulase PF00150.18 EGG14323.1 - 5.5e-27 94.9 2.6 1.7e-26 93.3 2.6 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EGG14323.1 - 2.1e-18 66.6 0.7 4.4e-18 65.6 0.7 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_1 PF00232.18 EGG14323.1 - 9.5e-05 21.0 0.1 0.00019 20.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 FERM_M PF00373.18 EGG14324.1 - 2.8e-45 153.5 7.6 3.1e-22 79.2 0.1 3.5 4 0 0 4 4 4 2 FERM central domain FERM_N PF09379.10 EGG14324.1 - 1.2e-23 82.8 1.7 1.9e-10 40.6 0.1 4.4 4 1 0 4 4 4 2 FERM N-terminal domain FERM_f0 PF16511.5 EGG14324.1 - 2.5e-10 40.5 6.7 4.7e-05 23.6 0.1 4.9 4 0 0 4 4 4 2 N-terminal or F0 domain of Talin-head FERM IRS PF02174.17 EGG14324.1 - 2.1e-05 24.3 0.0 0.00029 20.7 0.0 2.5 2 0 0 2 2 2 1 PTB domain (IRS-1 type) ACBP PF00887.19 EGG14324.1 - 0.0059 16.8 0.0 0.77 10.0 0.0 2.8 2 0 0 2 2 2 1 Acyl CoA binding protein PTB PF08416.13 EGG14324.1 - 0.033 14.3 0.6 0.29 11.3 0.0 2.7 3 0 0 3 3 3 0 Phosphotyrosine-binding domain ubiquitin PF00240.23 EGG14324.1 - 0.048 13.4 4.3 3.2 7.6 1.0 3.7 3 0 0 3 3 3 0 Ubiquitin family Rad60-SLD PF11976.8 EGG14324.1 - 0.087 12.7 6.0 1.2 9.0 0.6 3.9 5 0 0 5 5 5 0 Ubiquitin-2 like Rad60 SUMO-like DUF3439 PF11921.8 EGG14324.1 - 2.5 8.1 13.6 6.7 6.7 13.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ras PF00071.22 EGG14325.1 - 2.6e-57 192.9 0.1 3e-57 192.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG14325.1 - 4.2e-21 75.4 0.0 6e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG14325.1 - 2e-09 37.1 0.0 2.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG14325.1 - 1.2e-05 24.9 0.3 4e-05 23.3 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG14325.1 - 0.00052 20.1 0.0 0.00065 19.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGG14325.1 - 0.001 18.3 0.2 0.38 9.9 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 EGG14325.1 - 0.0028 17.6 2.0 1.5 8.7 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase Sod_Fe_C PF02777.18 EGG14327.1 - 1.5e-39 134.3 0.1 3e-39 133.3 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGG14327.1 - 3.8e-34 117.0 0.8 3.8e-34 117.0 0.8 2.2 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ribosomal_L11_N PF03946.14 EGG14327.1 - 0.087 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain PPR_2 PF13041.6 EGG14329.1 - 4.7e-31 106.7 13.1 6.7e-08 32.6 0.1 7.5 6 2 2 8 8 8 6 PPR repeat family PPR_3 PF13812.6 EGG14329.1 - 2.4e-22 78.8 16.5 0.00063 19.8 0.0 6.7 5 1 1 6 6 6 6 Pentatricopeptide repeat domain PPR_long PF17177.4 EGG14329.1 - 2.2e-19 69.7 0.4 1.5e-09 37.5 0.0 3.2 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EGG14329.1 - 1.6e-16 59.3 9.3 0.0023 18.0 0.1 7.5 8 0 0 8 8 8 4 PPR repeat DUF4282 PF14110.6 EGG14329.1 - 9.6e-13 48.7 10.7 1.8e-12 47.8 10.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) PPR_1 PF12854.7 EGG14329.1 - 5.2e-11 42.1 0.3 0.0009 18.9 0.1 4.7 4 0 0 4 4 4 3 PPR repeat UPF0158 PF03682.13 EGG14329.1 - 0.024 14.6 1.0 0.061 13.3 0.0 2.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0158) TPR_7 PF13176.6 EGG14329.1 - 0.039 14.0 0.1 25 5.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGG14329.1 - 0.041 13.5 0.0 0.52 9.9 0.0 2.7 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) BKACE PF05853.12 EGG14329.1 - 0.19 11.0 0.1 0.49 9.6 0.1 1.6 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme SET PF00856.28 EGG14330.1 - 9e-07 29.4 0.8 1.4e-06 28.8 0.2 1.8 2 0 0 2 2 2 1 SET domain TPR_12 PF13424.6 EGG14330.1 - 0.23 11.8 1.6 11 6.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-NOSIP PF15906.5 EGG14332.1 - 1.2e-13 51.0 0.8 1.2e-13 51.0 0.8 1.8 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EGG14332.1 - 2.4e-12 46.6 18.2 2e-07 30.9 5.7 2.8 2 1 0 2 2 2 2 RING-type zinc-finger Rtf2 PF04641.12 EGG14332.1 - 5e-11 42.5 5.8 5e-11 42.5 5.8 2.9 2 1 1 3 3 3 2 Rtf2 RING-finger zf-RING_2 PF13639.6 EGG14332.1 - 2.8e-09 37.2 22.8 0.00011 22.4 10.1 2.8 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 EGG14332.1 - 1.2e-07 31.5 22.6 7.9e-05 22.4 4.4 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG14332.1 - 1.5e-07 31.2 26.7 2.6e-05 24.0 11.2 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG14332.1 - 2.3e-07 30.5 22.1 7e-05 22.6 9.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EGG14332.1 - 7.9e-06 25.9 16.9 6.8e-05 22.9 5.9 2.5 2 0 0 2 2 2 2 FYVE zinc finger zf-C3HC4_4 PF15227.6 EGG14332.1 - 0.00013 22.0 20.5 0.023 14.9 6.1 3.0 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING DUF3449 PF11931.8 EGG14332.1 - 0.0012 18.6 8.7 0.0017 18.2 5.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-RING_5 PF14634.6 EGG14332.1 - 0.002 18.1 30.5 0.027 14.4 15.6 3.5 2 2 1 3 3 3 2 zinc-RING finger domain Baculo_IE-1 PF05290.11 EGG14332.1 - 0.0094 15.9 3.9 0.0094 15.9 3.9 2.3 2 1 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 EGG14332.1 - 0.12 12.3 25.5 0.46 10.4 9.2 3.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EGG14332.1 - 1.1 9.2 9.2 9.1 6.2 0.3 2.9 2 1 1 3 3 3 0 zf-RING of BARD1-type protein WD40 PF00400.32 EGG14333.1 - 2.9e-25 88.0 28.5 1.4e-06 28.9 0.2 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG14333.1 - 1.2e-15 57.5 4.2 1.9e-07 31.3 1.2 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG14333.1 - 2.4e-05 23.4 0.0 0.098 11.6 0.0 3.2 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4073 PF13285.6 EGG14333.1 - 0.014 15.0 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) TatD_DNase PF01026.21 EGG14334.1 - 1.7e-41 142.3 0.0 3.1e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 TatD related DNase Yippee-Mis18 PF03226.14 EGG14334.1 - 0.0045 17.2 2.6 0.0045 17.2 2.6 2.0 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Prothymosin PF03247.14 EGG14334.1 - 6.5 7.3 41.3 0.051 14.0 19.9 2.8 2 0 0 2 2 2 0 Prothymosin/parathymosin family UQ_con PF00179.26 EGG14335.1 - 2.5e-43 147.1 0.1 4e-43 146.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.6 EGG14335.1 - 2.6e-13 50.5 0.0 6.9e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EGG14335.1 - 8e-10 39.2 0.0 1.5e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Rad60-SLD PF11976.8 EGG14335.1 - 7.6e-06 25.7 0.0 6.4e-05 22.7 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGG14335.1 - 1.2e-05 25.0 0.1 2.6e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Prok-E2_B PF14461.6 EGG14335.1 - 0.00025 20.7 0.1 0.0015 18.2 0.0 2.2 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 EGG14335.1 - 0.063 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 RWD domain TUG-UBL1 PF11470.8 EGG14335.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 TUG ubiquitin-like domain Acetyltransf_10 PF13673.7 EGG14336.1 - 6.4e-09 35.8 0.0 1.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG14336.1 - 8.8e-09 35.6 0.0 1.5e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG14336.1 - 4.5e-08 33.4 0.1 9.8e-08 32.3 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGG14336.1 - 0.05 13.7 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG14336.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein PI3K_1B_p101 PF10486.9 EGG14338.1 - 2.6e-07 28.9 0.1 2.6e-07 28.9 0.1 3.5 2 2 1 4 4 4 2 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pacs-1 PF10254.9 EGG14338.1 - 9.7e-06 24.8 0.2 9.7e-06 24.8 0.2 2.8 3 0 0 3 3 3 1 PACS-1 cytosolic sorting protein CENP-B_dimeris PF09026.10 EGG14338.1 - 0.09 13.2 0.2 0.21 12.0 0.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WD40 PF00400.32 EGG14339.1 - 1.3e-25 89.1 20.2 5.6e-07 30.2 2.3 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG14339.1 - 1.1e-17 64.1 9.3 5.3e-07 29.9 0.4 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG14339.1 - 9.6e-08 31.3 6.3 0.0054 15.7 1.9 4.5 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGG14339.1 - 1.2e-05 25.3 4.0 0.0011 18.9 0.7 3.1 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EGG14339.1 - 0.00019 19.6 2.3 0.13 10.3 0.1 2.9 3 0 0 3 3 3 2 IKI3 family Nup160 PF11715.8 EGG14339.1 - 0.04 12.5 5.8 0.026 13.2 1.0 2.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 MTS PF05175.14 EGG14340.1 - 2.6e-07 30.3 0.0 1.3e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EGG14340.1 - 0.0047 16.4 0.1 0.021 14.2 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGG14340.1 - 0.0071 17.0 0.0 0.018 15.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGG14340.1 - 0.017 16.1 0.0 0.052 14.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EGG14340.1 - 0.054 13.2 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EGG14340.1 - 0.08 13.7 0.0 0.33 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGG14340.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Neurensin PF14927.6 EGG14341.1 - 0.029 14.1 0.1 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Neurensin His_kinase PF06580.13 EGG14342.1 - 3.1e-05 24.2 5.8 0.013 15.8 0.0 3.1 3 0 0 3 3 3 2 Histidine kinase DUF1722 PF08349.11 EGG14342.1 - 0.046 14.0 0.4 3.2 8.0 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1722) Herpes_UL17 PF04559.12 EGG14342.1 - 0.091 11.5 0.1 0.092 11.5 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein NLRC4_HD2 PF17776.1 EGG14342.1 - 0.23 12.0 0.9 1.3 9.5 0.1 2.3 2 1 0 2 2 2 0 NLRC4 helical domain HD2 WD40 PF00400.32 EGG14343.1 - 9.7e-09 35.7 4.1 0.0074 17.1 0.1 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG14343.1 - 0.0054 17.0 0.0 14 6.1 0.0 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 EGG14343.1 - 0.011 15.1 0.1 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Ge1_WD40 PF16529.5 EGG14343.1 - 0.12 11.3 0.0 0.32 9.9 0.0 1.6 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SR-25 PF10500.9 EGG14343.1 - 2 8.0 11.7 2.8 7.5 11.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 EGG14344.1 - 0.001 18.5 31.3 0.002 17.6 31.3 1.4 1 0 0 1 1 1 1 BUD22 RNA_pol_Rpc4 PF05132.14 EGG14344.1 - 0.0011 19.4 0.3 0.0011 19.4 0.3 1.8 2 0 0 2 2 1 1 RNA polymerase III RPC4 CobT PF06213.12 EGG14344.1 - 0.0017 17.8 24.2 0.0017 17.8 24.2 2.3 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT DUF2828 PF11443.8 EGG14344.1 - 0.0049 15.0 0.9 0.0084 14.2 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DDHD PF02862.17 EGG14344.1 - 0.0059 16.8 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 DDHD domain Presenilin PF01080.17 EGG14344.1 - 0.019 13.8 7.2 0.034 12.9 7.2 1.4 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EGG14344.1 - 0.028 14.2 17.0 1.2 8.9 11.7 3.0 2 1 1 3 3 3 0 Connexin EIIBC-GUT_N PF03612.14 EGG14344.1 - 0.11 12.2 4.9 0.27 10.9 4.9 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TRAP_alpha PF03896.16 EGG14344.1 - 0.39 9.9 24.1 4.3 6.5 0.2 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CPSF100_C PF13299.6 EGG14344.1 - 0.58 10.3 14.2 0.1 12.8 9.2 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 EGG14344.1 - 0.59 9.3 6.4 1.1 8.5 6.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.10 EGG14344.1 - 0.61 10.4 28.6 0.67 10.3 19.1 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Sigma70_ner PF04546.13 EGG14344.1 - 0.95 9.3 32.1 0.1 12.5 17.9 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2052 PF09747.9 EGG14344.1 - 1.9 8.6 37.5 0.45 10.6 25.5 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RP-C_C PF11800.8 EGG14344.1 - 3.2 7.8 6.8 6.2 6.9 6.8 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF913 PF06025.12 EGG14344.1 - 3.8 6.4 13.9 0.37 9.7 7.6 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF2126 PF09899.9 EGG14344.1 - 5.3 5.0 8.9 7.5 4.5 8.9 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Dynamin_N PF00350.23 EGG14344.1 - 5.9 6.9 9.3 2.2 8.3 5.9 2.0 2 0 0 2 2 2 0 Dynamin family GNAT_acetyltr_2 PF13718.6 EGG14344.1 - 9.4 5.6 12.6 26 4.1 12.6 1.7 1 0 0 1 1 1 0 GNAT acetyltransferase 2 FERM_f0 PF16511.5 EGG14345.1 - 4.3e-29 100.6 0.8 7.4e-25 87.1 0.0 3.3 3 1 0 3 3 3 2 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 EGG14345.1 - 1.6e-25 89.8 0.1 4.2e-25 88.4 0.1 1.7 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 EGG14345.1 - 2.5e-13 49.7 0.3 8.2e-13 48.1 0.2 2.0 2 0 0 2 2 2 1 FERM N-terminal domain PID PF00640.23 EGG14345.1 - 0.00029 20.9 0.7 0.00066 19.7 0.1 1.9 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) IRS PF02174.17 EGG14345.1 - 0.002 18.0 0.0 0.0052 16.7 0.0 1.7 1 0 0 1 1 1 1 PTB domain (IRS-1 type) RA PF00788.23 EGG14345.1 - 0.0097 16.5 0.1 0.025 15.2 0.1 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain ACBP PF00887.19 EGG14345.1 - 0.01 16.0 0.1 0.025 14.8 0.1 1.7 1 0 0 1 1 1 0 Acyl CoA binding protein I_LWEQ PF01608.17 EGG14346.1 - 2.9e-51 173.7 138.4 4.8e-41 140.5 15.6 15.8 5 4 11 17 17 17 10 I/LWEQ domain VBS PF08913.10 EGG14346.1 - 0.0021 18.5 76.5 0.0064 16.9 1.3 10.1 8 2 1 9 9 9 4 Vinculin Binding Site SipA_VBS PF17985.1 EGG14346.1 - 0.2 11.6 9.0 1.2 9.2 0.5 4.0 3 0 0 3 3 3 0 SipA vinculin binding site RunxI PF08504.11 EGG14346.1 - 4.9 7.9 9.0 5.2 7.8 0.8 4.2 3 0 0 3 3 3 0 Runx inhibition domain ABC2_membrane PF01061.24 EGG14347.1 - 2.8e-39 134.7 19.8 4e-39 134.2 19.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGG14347.1 - 1.4e-26 93.7 0.0 2.2e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PHO4 PF01384.20 EGG14347.1 - 7.6e-05 21.9 0.5 0.00011 21.4 0.5 1.3 1 0 0 1 1 1 1 Phosphate transporter family AAA_29 PF13555.6 EGG14347.1 - 8.1e-05 22.3 0.1 0.00018 21.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGG14347.1 - 0.00029 20.8 0.1 0.12 12.2 0.2 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EGG14347.1 - 0.00046 20.7 0.0 0.00082 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG14347.1 - 0.0013 19.2 0.0 0.0021 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EGG14347.1 - 0.0022 17.5 0.0 0.054 12.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGG14347.1 - 0.0026 17.7 1.1 0.0089 15.9 0.5 2.0 2 1 1 3 3 2 1 RsgA GTPase AAA_22 PF13401.6 EGG14347.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EGG14347.1 - 0.012 15.4 0.6 0.021 14.6 0.2 1.6 2 0 0 2 2 2 0 Cytidylate kinase Rad17 PF03215.15 EGG14347.1 - 0.017 15.1 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 EGG14347.1 - 0.027 15.0 0.4 0.065 13.7 0.0 1.7 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGG14347.1 - 0.039 13.9 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EGG14347.1 - 0.043 13.4 0.1 0.076 12.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGG14347.1 - 0.043 14.0 0.1 0.07 13.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGG14347.1 - 0.066 13.6 0.1 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 EGG14347.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGG14347.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGG14347.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 EGG14347.1 - 0.15 12.1 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RasGEF PF00617.19 EGG14350.1 - 1.4e-54 184.9 0.6 4.9e-54 183.2 0.6 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGG14350.1 - 4.4e-13 49.4 4.1 2.1e-12 47.2 0.0 3.5 3 0 0 3 3 3 1 RasGEF N-terminal motif Drf_GBD PF06371.13 EGG14350.1 - 4.6e-13 49.2 0.9 1.5e-12 47.5 0.9 1.9 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGG14350.1 - 1e-10 41.6 0.0 3e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Diaphanous FH3 Domain FERM_f0 PF16511.5 EGG14350.1 - 5.4e-05 23.4 0.1 0.41 11.0 0.0 4.5 5 0 0 5 5 5 2 N-terminal or F0 domain of Talin-head FERM Glyco_transf_17 PF04724.13 EGG14351.1 - 1.5e-14 53.8 0.1 3e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 17 Sterile PF03015.19 EGG14351.1 - 0.06 13.6 0.5 0.18 12.1 0.5 1.9 1 0 0 1 1 1 0 Male sterility protein Pepsin-I3 PF06394.13 EGG14351.1 - 0.089 13.0 0.5 0.19 11.9 0.5 1.5 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain O-antigen_lig PF13425.6 EGG14351.1 - 0.1 11.4 2.7 0.16 10.8 2.7 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF836 PF05768.14 EGG14351.1 - 0.12 12.8 0.7 4.9 7.6 0.6 2.5 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) DUF3573 PF12097.8 EGG14351.1 - 0.14 10.9 3.0 0.27 10.0 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Ras PF00071.22 EGG14352.1 - 7.9e-62 207.6 2.1 9.4e-62 207.4 2.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG14352.1 - 1.2e-36 125.6 2.3 1.2e-36 125.5 0.4 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG14352.1 - 3.1e-20 72.4 0.4 3.9e-20 72.0 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG14352.1 - 3.6e-08 33.2 0.7 8.2e-08 32.0 0.6 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGG14352.1 - 6.4e-08 32.2 1.5 8.5e-08 31.8 1.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EGG14352.1 - 8e-07 28.7 0.5 2.1e-06 27.3 0.5 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGG14352.1 - 2.3e-06 27.7 0.6 3.9e-06 26.9 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG14352.1 - 7.9e-05 22.6 0.4 0.083 12.8 0.3 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGG14352.1 - 0.00022 20.7 0.3 0.0003 20.3 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 EGG14352.1 - 0.046 14.1 0.2 3.7 8.0 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 EGG14352.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DNA_pol_E_B PF04042.16 EGG14352.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B RasGAP PF00616.19 EGG14353.1 - 1.9e-31 109.4 1.4 1.2e-30 106.8 0.0 2.6 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EGG14353.1 - 4.2e-16 59.3 3.1 1.1e-15 58.0 3.1 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 EGG14353.1 - 2.1e-13 50.3 1.8 4.8e-13 49.1 1.8 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain Myosin_TH1 PF06017.13 EGG14353.1 - 2.6e-08 33.7 7.9 0.00034 20.3 0.2 2.7 3 0 0 3 3 3 2 Unconventional myosin tail, actin- and lipid-binding DHFR_1 PF00186.19 EGG14354.1 - 4.8e-45 153.1 0.3 1.1e-44 152.0 0.3 1.6 1 1 0 1 1 1 1 Dihydrofolate reductase DUF16 PF01519.16 EGG14354.1 - 0.071 13.6 1.5 0.24 11.9 0.0 2.5 2 2 0 2 2 2 0 Protein of unknown function DUF16 TPP_enzyme_N PF02776.18 EGG14355.1 - 1.7e-14 53.8 0.0 9.3e-14 51.4 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGG14355.1 - 2.7e-08 33.7 0.0 6.2e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGG14355.1 - 0.00043 20.0 0.0 0.004 16.9 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain EGF_2 PF07974.13 EGG14356.1 - 9e-08 32.4 29.1 0.0015 18.8 10.6 2.6 2 0 0 2 2 2 2 EGF-like domain LRR_8 PF13855.6 EGG14356.1 - 2.9e-05 23.8 5.2 0.069 12.9 0.0 4.7 4 1 1 5 5 5 3 Leucine rich repeat DUF4216 PF13952.6 EGG14356.1 - 0.00036 20.9 0.5 1.7 9.1 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4216) Peptidase_C10 PF01640.17 EGG14356.1 - 0.0022 18.3 0.2 1.9 8.8 0.0 2.9 2 0 0 2 2 2 2 Peptidase C10 family DUF4837 PF16125.5 EGG14356.1 - 0.28 10.2 1.7 15 4.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4837) Laminin_EGF PF00053.24 EGG14356.1 - 2.4 8.4 27.4 5.7 7.2 9.4 2.5 2 0 0 2 2 2 0 Laminin EGF domain DUF5128 PF17170.4 EGG14357.1 - 0.00053 19.3 0.9 0.00072 18.8 0.9 1.2 1 0 0 1 1 1 1 6-bladed beta-propeller LRR_5 PF13306.6 EGG14357.1 - 0.0055 16.7 4.4 0.0055 16.7 4.4 2.3 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EGG14357.1 - 0.036 13.8 0.4 0.23 11.3 0.2 2.6 1 1 0 1 1 1 0 Leucine rich repeat LRR_4 PF12799.7 EGG14357.1 - 0.096 13.1 0.5 0.096 13.1 0.5 3.8 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGG14357.1 - 1.9 8.8 8.8 1.8 8.8 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Ank_5 PF13857.6 EGG14359.1 - 1e-05 25.7 0.0 2.3 8.7 0.0 5.4 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG14359.1 - 1.2e-05 25.8 0.8 0.86 10.3 0.1 5.3 3 1 2 5 5 5 2 Ankyrin repeats (many copies) FAM195 PF14799.6 EGG14359.1 - 0.033 14.5 0.5 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 FAM195 family Ank_3 PF13606.6 EGG14359.1 - 0.12 13.0 0.0 2e+02 3.1 0.0 5.2 5 0 0 5 5 5 0 Ankyrin repeat Sec10 PF07393.11 EGG14360.1 - 2.2e-107 360.3 21.6 5.1e-57 193.8 6.7 2.2 1 1 1 2 2 2 2 Exocyst complex component Sec10 ArdA PF07275.11 EGG14360.1 - 0.0026 18.4 0.2 0.19 12.3 0.0 2.6 2 0 0 2 2 2 1 Antirestriction protein (ArdA) PDE6_gamma PF04868.12 EGG14360.1 - 2 8.7 3.6 1.3 9.3 0.3 2.4 3 0 0 3 3 3 0 Retinal cGMP phosphodiesterase, gamma subunit Ribosomal_L39 PF00832.20 EGG14361.1 - 3.4e-13 49.0 2.9 7e-11 41.6 2.2 2.3 2 0 0 2 2 2 2 Ribosomal L39 protein DUF2465 PF10239.9 EGG14364.1 - 7.9e-35 120.6 2.0 2e-33 116.0 2.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2465) ERG2_Sigma1R PF04622.12 EGG14364.1 - 0.00062 19.2 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ERCC3_RAD25_C PF16203.5 EGG14365.1 - 1.1e-116 388.4 0.5 1.9e-116 387.5 0.5 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EGG14365.1 - 1e-37 129.1 0.0 2.1e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG14365.1 - 3.8e-13 49.8 0.2 2.7e-12 47.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGG14365.1 - 1.2e-12 48.2 0.2 4.5e-12 46.3 0.2 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EGG14365.1 - 8.9e-07 27.9 0.0 1.8e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF3886 PF13025.6 EGG14365.1 - 0.69 10.1 3.6 1.5 9.0 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Connexin PF00029.19 EGG14366.1 - 0.00068 19.5 1.1 0.001 18.9 1.1 1.3 1 0 0 1 1 1 1 Connexin Orf78 PF06024.12 EGG14366.1 - 0.0012 19.1 0.5 0.0053 17.0 0.5 1.9 1 1 0 1 1 1 1 Orf78 (ac78) CDC45 PF02724.14 EGG14366.1 - 0.0025 16.2 1.1 0.0025 16.2 1.1 1.1 1 0 0 1 1 1 1 CDC45-like protein CLN3 PF02487.17 EGG14366.1 - 0.025 13.7 0.2 0.031 13.3 0.2 1.0 1 0 0 1 1 1 0 CLN3 protein KleE PF17394.2 EGG14366.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein MscS_TM PF12794.7 EGG14366.1 - 0.16 10.8 0.1 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 PTPRCAP PF15713.5 EGG14366.1 - 0.5 10.7 9.1 0.74 10.1 9.1 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated eIF-4B PF06273.11 EGG14366.1 - 0.52 9.3 9.0 0.69 8.9 9.0 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B RR_TM4-6 PF06459.12 EGG14366.1 - 0.58 9.9 8.7 0.76 9.6 8.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med19 PF10278.9 EGG14366.1 - 8.2 6.3 16.3 11 5.9 16.3 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Ly49 PF08391.10 EGG14367.1 - 0.025 14.9 0.1 0.036 14.4 0.1 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region ETF PF01012.21 EGG14368.1 - 7.4e-44 149.8 1.1 8.9e-44 149.5 1.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Methyltransf_16 PF10294.9 EGG14371.1 - 5.1e-19 68.7 0.0 8.5e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EGG14371.1 - 0.0045 16.5 0.0 0.0079 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGG14371.1 - 0.0099 15.7 0.1 0.018 14.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGG14371.1 - 0.018 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DpnI_C PF17726.1 EGG14371.1 - 0.1 12.7 1.3 0.14 12.3 0.2 1.8 2 0 0 2 2 2 0 Dam-replacing HTH domain NtA PF03146.15 EGG14371.1 - 0.15 11.9 0.6 0.5 10.3 0.1 1.9 2 0 0 2 2 2 0 Agrin NtA domain Sec39 PF08314.11 EGG14372.1 - 7.7e-21 74.3 18.5 6e-10 38.2 1.6 4.5 3 1 1 4 4 4 3 Secretory pathway protein Sec39 Nbas_N PF15492.6 EGG14372.1 - 4.4e-14 52.5 2.7 1.8e-09 37.3 0.1 2.6 2 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal ANAPC4_WD40 PF12894.7 EGG14372.1 - 0.00028 21.1 0.1 0.23 11.8 0.0 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ras PF00071.22 EGG14373.1 - 2.6e-08 33.6 0.4 4.3e-06 26.4 0.0 2.9 1 1 0 2 2 2 1 Ras family VWA_2 PF13519.6 EGG14373.1 - 6.4e-06 26.8 0.0 1.5e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain ubiquitin PF00240.23 EGG14373.1 - 0.0002 21.1 0.0 0.00072 19.3 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin family Roc PF08477.13 EGG14373.1 - 0.00027 21.1 0.3 0.057 13.6 0.0 3.0 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EGG14373.1 - 0.041 14.2 0.0 0.18 12.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGG14373.1 - 0.26 11.8 11.3 1.6 9.2 4.4 3.0 3 1 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 EGG14374.1 - 1.1e-44 152.4 0.0 1.5e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGG14374.1 - 5.8e-25 87.8 0.2 1.4e-24 86.5 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGG14374.1 - 2e-06 28.1 0.3 1.6e-05 25.2 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGG14374.1 - 9e-05 22.5 0.4 0.00087 19.4 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGG14374.1 - 0.02 14.0 0.3 0.069 12.3 0.0 1.9 2 1 1 3 3 3 0 G-protein alpha subunit PAM2 PF07145.15 EGG14374.1 - 0.089 12.5 0.2 0.2 11.4 0.2 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region PRCC PF10253.9 EGG14374.1 - 0.1 13.4 3.3 0.16 12.8 3.3 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting PduV-EutP PF10662.9 EGG14374.1 - 2.9 7.6 4.9 83 2.9 0.0 3.8 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation DUF3439 PF11921.8 EGG14374.1 - 3.8 7.5 11.6 8.3 6.4 11.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CMV_1a PF12467.8 EGG14374.1 - 4 7.7 7.4 8 6.8 7.4 1.5 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Ribonuclease_3 PF00636.26 EGG14376.1 - 1e-37 128.9 0.2 4.1e-18 65.9 0.0 4.0 2 2 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGG14376.1 - 4.5e-31 107.7 0.0 1.5e-15 57.5 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 EGG14377.1 - 6.3e-11 42.8 0.6 1e-10 42.1 0.6 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif ORF6C PF10552.9 EGG14377.1 - 0.0078 16.3 0.6 0.41 10.8 0.1 2.6 3 0 0 3 3 3 1 ORF6C domain eIF-3_zeta PF05091.12 EGG14377.1 - 0.012 14.7 0.5 0.013 14.5 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DND1_DSRM PF14709.7 EGG14377.1 - 0.012 15.8 0.1 0.029 14.6 0.1 1.7 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF2967 PF11179.8 EGG14377.1 - 1.2 7.2 20.0 0.0081 14.3 11.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) DUF3446 PF11928.8 EGG14377.1 - 1.8 9.0 7.3 7.3 7.0 1.2 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Rrn6 PF10214.9 EGG14377.1 - 2.7 6.4 10.8 3.8 5.9 10.8 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SAPS PF04499.15 EGG14378.1 - 3e-55 187.9 1.7 1.7e-44 152.5 1.7 3.3 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein SDA1 PF05285.12 EGG14378.1 - 0.81 9.0 15.1 1.2 8.5 15.1 1.2 1 0 0 1 1 1 0 SDA1 Tfb4 PF03850.14 EGG14378.1 - 1.9 7.9 4.1 3.1 7.2 3.1 1.8 2 0 0 2 2 2 0 Transcription factor Tfb4 UPF0128 PF03673.13 EGG14379.1 - 0.015 14.8 0.9 0.12 11.9 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0128) Ribosomal_S13_N PF08069.12 EGG14379.1 - 0.029 14.4 3.2 0.077 13.0 0.7 2.6 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain zf-HC5HC2H_2 PF13832.6 EGG14379.1 - 0.071 13.3 1.4 0.17 12.1 1.4 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain Ribosomal_L38e PF01781.18 EGG14380.1 - 2.3e-29 101.3 3.6 2.5e-29 101.1 3.6 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family FmiP_Thoc5 PF09766.9 EGG14381.1 - 2.1e-27 96.4 25.2 1.6e-15 57.3 21.5 2.3 1 1 1 2 2 2 2 Fms-interacting protein/Thoc5 DUF61 PF01886.16 EGG14381.1 - 0.02 14.9 2.8 0.038 14.0 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF61 TPR_MLP1_2 PF07926.12 EGG14381.1 - 0.022 14.8 5.2 0.022 14.8 5.2 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4107 PF13389.6 EGG14381.1 - 0.051 13.7 0.5 0.051 13.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) KASH_CCD PF14662.6 EGG14381.1 - 0.062 13.1 24.1 0.37 10.6 8.8 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH PH_13 PF16652.5 EGG14381.1 - 0.12 12.1 5.5 0.19 11.5 5.3 1.4 1 1 0 1 1 1 0 Pleckstrin homology domain HIP1_clath_bdg PF16515.5 EGG14381.1 - 0.16 12.6 21.0 0.14 12.8 5.0 2.9 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Methyltransf_14 PF08484.11 EGG14381.1 - 0.21 11.4 0.7 0.55 10.0 0.7 1.6 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Mvb12 PF09452.10 EGG14381.1 - 1.8 9.1 7.9 0.92 10.0 1.3 2.7 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 DUF4164 PF13747.6 EGG14381.1 - 2 8.8 8.3 1.1 9.6 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF1664 PF07889.12 EGG14381.1 - 2.5 8.2 11.8 1.7 8.7 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EGG14381.1 - 6.9 5.9 8.9 12 5.2 8.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GPO PF05929.11 EGG14381.1 - 7.6 6.1 11.8 2.4 7.7 1.4 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase ZapB PF06005.12 EGG14381.1 - 8.2 7.0 22.2 0.5 10.8 1.8 3.0 2 1 1 3 3 3 0 Cell division protein ZapB CREPT PF16566.5 EGG14381.1 - 8.7 6.5 19.7 0.62 10.2 5.9 2.5 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HA2 PF04408.23 EGG14382.1 - 1.1e-16 61.1 2.5 2.3e-16 60.0 0.0 2.9 3 0 0 3 3 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGG14382.1 - 4e-16 59.1 0.2 2.3e-15 56.7 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGG14382.1 - 9.4e-15 54.9 0.0 4.1e-14 52.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG14382.1 - 3.1e-11 43.4 0.0 9.8e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 EGG14382.1 - 5.1e-11 42.9 1.2 3.6e-09 36.9 1.2 3.2 1 1 0 1 1 1 1 RWD domain DND1_DSRM PF14709.7 EGG14382.1 - 1.2e-05 25.4 0.4 1.2e-05 25.4 0.4 2.0 2 0 0 2 2 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.6 EGG14382.1 - 0.0002 21.6 1.7 0.00071 19.9 0.5 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGG14382.1 - 0.0062 16.9 0.1 0.071 13.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain RuvA_C PF07499.13 EGG14382.1 - 0.011 16.2 0.0 13 6.3 0.0 3.1 2 0 0 2 2 2 0 RuvA, C-terminal domain T2SSE PF00437.20 EGG14382.1 - 0.013 14.5 0.0 0.032 13.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 EGG14382.1 - 0.02 14.2 0.0 0.063 12.6 0.0 1.8 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 EGG14382.1 - 0.047 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 EGG14382.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ParBc_2 PF08857.11 EGG14382.1 - 0.092 12.8 0.6 4.4 7.4 0.1 2.9 3 0 0 3 3 3 0 Putative ParB-like nuclease dsRBD2 PF17842.1 EGG14382.1 - 0.095 12.9 0.1 0.095 12.9 0.1 3.9 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 AAA_23 PF13476.6 EGG14382.1 - 0.11 13.0 0.0 0.11 13.0 0.0 4.1 3 1 1 4 4 3 0 AAA domain VWA_2 PF13519.6 EGG14383.1 - 1.6e-15 57.6 0.0 9.7e-15 55.1 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EGG14383.1 - 0.0013 19.0 0.1 0.007 16.6 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain Exonuc_VII_L PF02601.15 EGG14383.1 - 0.16 11.5 15.4 1.3 8.5 8.3 2.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Neur_chan_memb PF02932.16 EGG14383.1 - 4.3 7.3 12.0 13 5.8 0.1 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 EGG14383.1 - 5 6.4 21.9 7.1 5.9 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MAT1 PF06391.13 EGG14383.1 - 9.8 5.9 41.9 0.31 10.8 5.5 2.5 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 UQ_con PF00179.26 EGG14384.1 - 8.3e-20 70.9 0.4 1.5e-19 70.0 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SPOUT_MTase PF02590.17 EGG14384.1 - 0.033 14.2 0.2 0.056 13.4 0.2 1.3 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase HABP4_PAI-RBP1 PF04774.15 EGG14387.1 - 0.00015 22.6 0.2 0.00018 22.4 0.2 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Arf PF00025.21 EGG14388.1 - 3.2e-32 111.4 0.0 3.7e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG14388.1 - 2.6e-07 30.2 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG14388.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGG14388.1 - 0.0002 21.6 0.0 0.00036 20.7 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGG14388.1 - 0.00053 19.5 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGG14388.1 - 0.0024 17.1 0.7 0.095 11.8 0.0 2.4 1 1 1 2 2 2 1 G-protein alpha subunit AAA_7 PF12775.7 EGG14388.1 - 0.0042 16.6 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_29 PF13555.6 EGG14388.1 - 0.0081 15.9 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG14388.1 - 0.14 12.6 0.5 0.34 11.3 0.5 1.7 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 EGG14388.1 - 0.18 11.4 1.3 11 5.6 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SAP PF02037.27 EGG14389.1 - 3.5e-11 42.6 0.4 8.9e-11 41.3 0.4 1.7 1 0 0 1 1 1 1 SAP domain DUF218 PF02698.17 EGG14389.1 - 0.058 13.4 0.6 0.085 12.9 0.6 1.3 1 0 0 1 1 1 0 DUF218 domain Packaging_FI PF14000.6 EGG14389.1 - 0.69 10.4 6.3 0.062 13.8 1.2 1.9 2 0 0 2 2 2 0 DNA packaging protein FI Tho1_MOS11_C PF18592.1 EGG14389.1 - 4.5 7.2 8.6 1.1 9.2 0.1 3.5 5 0 0 5 5 5 0 Tho1/MOS11 C-terminal domain Utp14 PF04615.13 EGG14390.1 - 0.58 8.7 19.9 0.81 8.2 19.9 1.2 1 0 0 1 1 1 0 Utp14 protein HMG_box PF00505.19 EGG14391.1 - 1.8e-16 60.3 1.4 1.8e-16 60.3 1.4 1.8 2 0 0 2 2 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGG14391.1 - 5.5e-07 30.1 0.3 5.5e-07 30.1 0.3 1.7 2 0 0 2 2 2 1 HMG-box domain SDA1 PF05285.12 EGG14391.1 - 0.0039 16.7 21.1 0.0052 16.3 21.1 1.3 1 0 0 1 1 1 1 SDA1 PBP1_TM PF14812.6 EGG14391.1 - 0.014 15.7 6.3 0.014 15.7 6.3 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BUD22 PF09073.10 EGG14391.1 - 0.029 13.7 20.5 0.039 13.3 20.5 1.3 1 0 0 1 1 1 0 BUD22 MATalpha_HMGbox PF04769.12 EGG14391.1 - 0.051 12.9 0.4 0.11 11.8 0.4 1.5 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box DUF2457 PF10446.9 EGG14391.1 - 0.1 11.7 20.1 0.16 11.1 20.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PI3K_1B_p101 PF10486.9 EGG14391.1 - 0.27 8.9 9.3 0.29 8.9 9.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 EGG14391.1 - 0.71 7.9 29.3 0.94 7.5 29.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi YABBY PF04690.13 EGG14391.1 - 1.9 9.0 10.1 6.1 7.4 10.1 2.0 1 1 0 1 1 1 0 YABBY protein GAGA_bind PF06217.12 EGG14391.1 - 7.9 6.7 11.3 14 5.8 11.3 1.5 1 1 0 1 1 1 0 GAGA binding protein-like family Histone PF00125.24 EGG14392.1 - 9.6e-15 55.1 0.6 9.6e-15 55.1 0.6 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGG14392.1 - 1.3e-10 41.4 0.0 2.8e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 EGG14392.1 - 2.8e-07 30.1 0.5 2.8e-07 30.1 0.5 2.2 2 0 0 2 2 2 1 C-terminus of histone H2A TAFII28 PF04719.14 EGG14392.1 - 0.034 14.2 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF3464 PF11947.8 EGG14392.1 - 0.49 10.1 2.9 0.75 9.5 0.3 2.0 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 WD40 PF00400.32 EGG14393.1 - 1.5e-34 117.4 31.3 4.3e-06 27.4 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 EGG14393.1 - 4.4e-12 45.7 1.3 1e-11 44.5 1.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG14393.1 - 6.3e-08 32.3 1.7 1.2e-07 31.4 0.7 2.0 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 EGG14393.1 - 2.4e-07 30.9 6.3 0.18 12.1 0.1 4.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_5 PF18511.1 EGG14393.1 - 0.0007 19.1 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 F-box Nup160 PF11715.8 EGG14393.1 - 0.0027 16.4 15.3 0.37 9.4 0.1 4.6 3 2 2 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EGG14393.1 - 0.0068 15.8 0.6 0.13 11.5 0.1 2.8 3 1 0 3 3 3 1 WD40-like domain F-box_4 PF15966.5 EGG14393.1 - 0.016 15.1 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 F-box CNP1 PF08750.11 EGG14393.1 - 0.04 13.9 0.1 0.15 12.0 0.1 2.0 2 0 0 2 2 2 0 CNP1-like family RhoGEF PF00621.20 EGG14394.1 - 4.2e-44 151.0 4.8 4.2e-44 151.0 4.8 3.9 4 0 0 4 4 4 1 RhoGEF domain CH PF00307.31 EGG14394.1 - 1.6e-10 41.1 0.0 8.6e-10 38.8 0.0 2.4 1 0 0 1 1 1 1 Calponin homology (CH) domain PH PF00169.29 EGG14394.1 - 8.4e-05 23.0 0.3 0.00076 20.0 0.0 2.9 2 0 0 2 2 2 1 PH domain IQ PF00612.27 EGG14394.1 - 0.037 13.8 2.7 0.084 12.7 2.7 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif SLBP_RNA_bind PF15247.6 EGG14395.1 - 2.1e-30 104.7 3.0 2.1e-30 104.7 3.0 2.2 3 0 0 3 3 3 1 Histone RNA hairpin-binding protein RNA-binding domain SOBP PF15279.6 EGG14395.1 - 7 7.2 17.4 9.1 6.8 17.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein FHA PF00498.26 EGG14396.1 - 1.2e-14 54.3 0.2 3.7e-14 52.8 0.1 1.9 2 0 0 2 2 2 1 FHA domain Pkinase_Tyr PF07714.17 EGG14396.1 - 4.5e-06 26.1 0.5 9.4e-06 25.1 0.2 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG14396.1 - 5.4e-06 25.6 0.2 5.4e-06 25.6 0.2 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Sec7 PF01369.20 EGG14398.1 - 3.8e-44 150.6 8.3 3.8e-44 150.6 8.3 2.6 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.10 EGG14398.1 - 5.6e-31 106.2 10.4 8.7e-31 105.6 0.3 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) DCB PF16213.5 EGG14398.1 - 4e-20 72.2 8.6 3.1e-18 66.0 0.0 4.2 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EGG14398.1 - 8.8e-19 68.0 25.5 5.9e-18 65.3 8.9 5.8 5 1 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TFCD_C PF12612.8 EGG14398.1 - 0.0069 16.2 0.0 0.025 14.4 0.0 2.1 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal Katanin_con80 PF13925.6 EGG14398.1 - 0.05 13.6 1.2 0.27 11.3 1.2 2.3 1 0 0 1 1 1 0 con80 domain of Katanin HEAT PF02985.22 EGG14399.1 - 1.1e-05 25.2 0.2 0.00019 21.4 0.0 3.2 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 EGG14399.1 - 1.1e-05 25.7 0.1 0.011 16.2 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 EGG14399.1 - 0.00067 20.1 0.1 4.7 7.8 0.0 3.8 4 0 0 4 4 4 2 HEAT-like repeat DUF2052 PF09747.9 EGG14399.1 - 0.0089 16.2 11.4 0.018 15.2 11.4 1.5 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Vac14_Fab1_bd PF12755.7 EGG14399.1 - 0.011 16.4 1.3 0.34 11.5 0.1 3.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region UME PF08064.13 EGG14399.1 - 2.2 8.3 6.2 1.4 8.9 0.0 3.5 3 1 0 3 3 3 0 UME (NUC010) domain CobT PF06213.12 EGG14399.1 - 3.4 7.0 10.1 6.4 6.1 10.1 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-B_dimeris PF09026.10 EGG14399.1 - 5 7.6 11.1 12 6.4 11.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_60s PF00428.19 EGG14399.1 - 7.9 7.1 13.5 20 5.8 13.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Dicty_spore_N PF04562.12 EGG14400.1 - 2.8e-08 34.5 20.0 5e-08 33.7 20.0 1.4 1 0 0 1 1 1 1 Dictyostelium spore coat protein, N terminus PT PF04886.12 EGG14400.1 - 0.025 14.1 31.4 0.025 14.1 22.2 3.5 2 2 0 2 2 2 0 PT repeat HEAT PF02985.22 EGG14401.1 - 7.8e-10 38.2 11.4 1.3 9.4 0.1 11.2 13 0 0 13 13 13 2 HEAT repeat CLASP_N PF12348.8 EGG14401.1 - 7e-08 32.3 0.7 0.0036 16.9 0.0 4.4 5 0 0 5 5 5 2 CLASP N terminal Cnd1 PF12717.7 EGG14401.1 - 1.9e-07 31.3 22.0 0.035 14.1 0.1 8.2 6 2 2 8 8 8 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGG14401.1 - 5.6e-05 23.5 0.5 7.9 7.1 0.0 7.4 5 2 2 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGG14401.1 - 0.0018 18.8 12.0 3.2 8.4 0.1 7.9 8 0 0 8 8 8 1 Vacuolar 14 Fab1-binding region Tautomerase_2 PF14552.6 EGG14401.1 - 0.053 13.6 0.0 18 5.5 0.0 3.1 2 0 0 2 2 2 0 Tautomerase enzyme Arm PF00514.23 EGG14401.1 - 0.091 12.8 1.0 14 5.9 0.0 5.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat SLAM PF06214.11 EGG14401.1 - 0.1 12.6 0.5 0.65 10.0 0.0 2.7 3 0 0 3 3 3 0 Signaling lymphocytic activation molecule (SLAM) protein CUTL PF16557.5 EGG14401.1 - 1.9 8.7 3.7 4.3 7.6 0.0 3.7 4 0 0 4 4 4 0 CUT1-like DNA-binding domain of SATB Ferlin_C PF16165.5 EGG14403.1 - 0.4 10.6 4.3 0.73 9.8 1.0 3.1 2 1 1 3 3 3 0 Ferlin C-terminus HEAT PF02985.22 EGG14404.1 - 0.022 15.0 0.2 53 4.5 0.1 5.0 5 0 0 5 5 5 0 HEAT repeat Rep_fac_C PF08542.11 EGG14404.1 - 0.092 13.2 1.4 0.43 11.0 0.2 2.9 2 0 0 2 2 2 0 Replication factor C C-terminal domain Vac14_Fab1_bd PF12755.7 EGG14404.1 - 0.87 10.2 7.8 8.4 7.1 0.1 5.4 7 2 1 8 8 8 0 Vacuolar 14 Fab1-binding region Acetyltransf_2 PF00797.17 EGG14405.1 - 2.9e-17 63.3 0.2 3.4e-17 63.0 0.2 1.1 1 0 0 1 1 1 1 N-acetyltransferase HEAT PF02985.22 EGG14406.1 - 2.5e-07 30.4 0.2 0.089 13.1 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat Vac14_Fab1_bd PF12755.7 EGG14406.1 - 0.00095 19.7 6.6 0.13 12.9 0.5 4.5 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region Sec7_N PF12783.7 EGG14406.1 - 0.0066 16.4 4.9 0.013 15.4 0.4 3.5 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal CLASP_N PF12348.8 EGG14406.1 - 0.018 14.6 1.1 0.018 14.6 1.1 3.4 4 1 0 4 4 4 0 CLASP N terminal HEAT_EZ PF13513.6 EGG14406.1 - 0.077 13.5 0.0 39 4.9 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat MMS19_N PF14500.6 EGG14406.1 - 0.085 12.4 3.7 0.22 11.1 0.8 2.9 3 2 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 EGG14406.1 - 0.17 12.3 0.0 4.5 7.7 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats Cnd1 PF12717.7 EGG14406.1 - 0.88 9.6 8.7 1 9.4 4.1 3.5 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Ribosomal_S8 PF00410.19 EGG14407.1 - 5.4e-14 52.2 0.0 1.1e-13 51.2 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S8 Myb_DNA-bind_4 PF13837.6 EGG14409.1 - 0.088 13.2 0.2 0.099 13.0 0.2 1.2 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Pox_A32 PF04665.12 EGG14410.1 - 0.00018 21.0 0.1 0.00095 18.7 0.1 2.0 2 0 0 2 2 2 1 Poxvirus A32 protein BppL_N PF18338.1 EGG14410.1 - 0.0014 18.3 0.2 0.0059 16.3 0.2 2.1 1 0 0 1 1 1 1 Lower baseplate protein N-terminal domain AAA_22 PF13401.6 EGG14410.1 - 0.0076 16.5 0.0 0.021 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGG14410.1 - 0.023 14.2 0.1 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 EGG14410.1 - 0.026 14.4 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 EGG14410.1 - 0.03 14.7 0.0 0.069 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGG14410.1 - 0.03 14.2 0.4 0.056 13.4 0.4 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ResIII PF04851.15 EGG14410.1 - 0.13 12.3 2.0 0.14 12.2 0.3 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PrgU PF09627.10 EGG14412.1 - 0.0017 18.3 0.6 0.0017 18.3 0.6 2.2 1 1 1 2 2 2 1 PrgU-like protein SAM_2 PF07647.17 EGG14413.1 - 1e-07 31.9 0.1 0.00012 22.1 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 EGG14413.1 - 8.4e-06 25.9 0.2 0.14 12.4 0.1 2.6 2 0 0 2 2 2 2 Ste50p, sterile alpha motif DAP3 PF10236.9 EGG14413.1 - 3.6e-05 23.1 0.0 8.7e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 SAM_1 PF00536.30 EGG14413.1 - 0.0005 20.5 0.2 0.014 15.9 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) FlbT PF07378.11 EGG14413.1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Flagellar protein FlbT AAA_16 PF13191.6 EGG14413.1 - 0.13 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Coilin_N PF15862.5 EGG14415.1 - 0.00089 19.1 2.4 0.00089 19.1 2.4 1.7 1 1 1 2 2 2 1 Coilin N-terminus Nop14 PF04147.12 EGG14415.1 - 0.0073 14.6 8.2 0.0081 14.4 8.2 1.0 1 0 0 1 1 1 1 Nop14-like family PAXIP1_C PF15364.6 EGG14415.1 - 0.0095 16.2 9.2 0.013 15.8 9.2 1.2 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein SDA1 PF05285.12 EGG14415.1 - 0.012 15.0 9.1 0.015 14.8 9.1 1.0 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.11 EGG14415.1 - 0.041 12.0 5.4 0.044 11.9 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RPN2_C PF18004.1 EGG14415.1 - 0.067 13.1 11.7 0.094 12.6 11.7 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Med8 PF10232.9 EGG14415.1 - 0.093 12.3 6.6 0.13 11.8 6.6 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Tim54 PF11711.8 EGG14415.1 - 0.12 11.1 9.6 0.15 10.8 9.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DNA_pol_phi PF04931.13 EGG14415.1 - 0.15 10.2 10.6 0.17 9.9 10.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EGG14415.1 - 0.19 10.0 10.4 0.22 9.8 10.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 EGG14415.1 - 0.2 10.6 2.7 0.23 10.4 2.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TFB6 PF17110.5 EGG14415.1 - 0.24 11.2 4.3 0.32 10.7 4.3 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PTPRCAP PF15713.5 EGG14415.1 - 0.35 11.2 12.2 0.47 10.7 12.2 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Pox_Ag35 PF03286.14 EGG14415.1 - 0.39 10.5 10.2 0.53 10.0 10.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-N PF05238.13 EGG14415.1 - 0.42 9.9 7.4 0.51 9.6 7.4 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like CPSF100_C PF13299.6 EGG14415.1 - 0.51 10.5 6.3 0.69 10.1 6.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 EGG14415.1 - 0.7 9.7 11.2 0.85 9.4 11.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.15 EGG14415.1 - 0.92 8.4 1.8 1.1 8.2 1.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TRAP_alpha PF03896.16 EGG14415.1 - 1.1 8.4 7.1 1.3 8.1 7.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Zip PF02535.22 EGG14415.1 - 1.1 8.4 2.6 1.2 8.3 2.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SMN PF06003.12 EGG14415.1 - 1.3 8.2 8.4 1.9 7.7 8.4 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) HSP70 PF00012.20 EGG14415.1 - 1.3 7.1 7.2 1.6 6.8 7.2 1.0 1 0 0 1 1 1 0 Hsp70 protein CSRNP_N PF16019.5 EGG14415.1 - 1.4 8.8 6.8 1.9 8.3 6.8 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus FAM176 PF14851.6 EGG14415.1 - 1.4 8.6 11.9 2.1 8.0 11.9 1.2 1 0 0 1 1 1 0 FAM176 family DUF4820 PF16091.5 EGG14415.1 - 1.7 8.0 7.1 2.3 7.5 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Nucleo_P87 PF07267.11 EGG14415.1 - 2.6 6.8 9.3 3.4 6.4 9.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 EGG14415.1 - 5.6 5.6 8.6 6.8 5.3 8.6 1.1 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 EGG14415.1 - 6.4 6.0 16.0 8.9 5.5 16.0 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4637 PF15470.6 EGG14415.1 - 7 6.3 12.0 10 5.8 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CobT PF06213.12 EGG14415.1 - 7.9 5.8 15.2 10 5.4 15.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT V_ATPase_I PF01496.19 EGG14415.1 - 9.6 4.0 7.0 12 3.7 7.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CAC1F_C PF16885.5 EGG14416.1 - 0.0031 17.3 10.4 0.0035 17.1 10.4 1.1 1 0 0 1 1 1 1 Voltage-gated calcium channel subunit alpha, C-term XAP5 PF04921.14 EGG14416.1 - 0.0032 17.3 9.5 0.0032 17.3 9.5 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator PI3K_1B_p101 PF10486.9 EGG14416.1 - 0.2 9.4 10.6 0.24 9.1 10.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.12 EGG14416.1 - 0.24 10.7 6.1 0.49 9.7 6.1 1.5 1 0 0 1 1 1 0 NOA36 protein GREB1 PF15782.5 EGG14416.1 - 1.3 6.0 18.2 1.6 5.7 18.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CENP-B_dimeris PF09026.10 EGG14418.1 - 0.00018 21.8 8.6 0.00037 20.8 8.6 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 EGG14418.1 - 0.0031 17.4 15.5 0.0056 16.6 15.5 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region Sporozoite_P67 PF05642.11 EGG14418.1 - 0.017 13.2 6.6 0.024 12.7 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BSP_II PF05432.11 EGG14418.1 - 0.034 13.8 17.1 0.062 13.0 17.1 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DNA_pol_phi PF04931.13 EGG14418.1 - 0.079 11.1 18.8 0.11 10.6 18.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2052 PF09747.9 EGG14418.1 - 0.082 13.0 22.5 0.19 11.8 22.5 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pox_A30L_A26L PF06086.12 EGG14418.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein RRN3 PF05327.11 EGG14418.1 - 0.18 10.3 16.5 0.25 9.8 16.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TMEM232 PF15877.5 EGG14418.1 - 0.24 10.4 4.5 0.27 10.2 0.9 2.1 2 0 0 2 2 2 0 Transmembrane protein family 232 CDC45 PF02724.14 EGG14418.1 - 1.3 7.2 19.8 1.7 6.8 19.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DOR PF14839.6 EGG14418.1 - 4.8 7.1 20.5 9.1 6.2 20.5 1.4 1 0 0 1 1 1 0 DOR family NOA36 PF06524.12 EGG14418.1 - 5.9 6.1 20.6 0.26 10.6 15.0 1.5 2 0 0 2 2 2 0 NOA36 protein ILEI PF15711.5 EGG14420.1 - 0.0058 17.1 0.0 0.29 11.6 0.0 2.7 1 1 0 1 1 1 1 Interleukin-like EMT inducer H_lectin PF09458.10 EGG14421.1 - 2.4e-17 62.9 1.3 4.6e-17 62.0 0.2 2.2 2 1 0 2 2 2 1 H-type lectin domain F5_F8_type_C PF00754.25 EGG14421.1 - 1.9e-15 57.1 0.4 2.9e-15 56.5 0.4 1.3 1 0 0 1 1 1 1 F5/8 type C domain Glyco_hydro_31 PF01055.26 EGG14422.1 - 5.9e-155 516.8 5.9 7.4e-155 516.4 5.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EGG14422.1 - 2.6e-28 98.5 0.0 5e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EGG14422.1 - 7.4e-13 48.6 3.7 2.3e-12 47.0 0.3 3.1 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 EGG14422.1 - 0.027 14.8 0.1 0.082 13.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) DUF1533 PF07550.11 EGG14422.1 - 0.15 12.0 0.2 2.5 8.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) Guanylate_cyc PF00211.20 EGG14423.1 - 2.8e-27 95.5 1.6 9.9e-15 54.6 0.0 2.9 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 EGG14423.1 - 1.2e-09 38.8 0.0 3.6e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG14423.1 - 5.7e-05 23.4 0.1 0.00031 21.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_12 PF13424.6 EGG14423.1 - 0.0051 17.1 0.8 0.0051 17.1 0.8 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat SIR2 PF02146.17 EGG14423.1 - 0.0077 16.2 0.9 2.5 8.0 0.0 3.4 3 0 0 3 3 3 1 Sir2 family TPR_MalT PF17874.1 EGG14423.1 - 0.016 14.6 2.8 0.037 13.4 2.8 1.5 1 0 0 1 1 1 0 MalT-like TPR region Gln-synt_C PF00120.24 EGG14424.1 - 1.6e-76 257.5 0.0 1.9e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 EGG14424.1 - 0.00041 20.1 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain RICTOR_phospho PF14665.6 EGG14425.1 - 0.013 15.9 0.4 0.02 15.2 0.1 1.4 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Lung_7-TM_R PF06814.13 EGG14427.1 - 1.4e-06 27.8 24.2 2.9e-06 26.7 24.2 1.6 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF2992 PF11208.8 EGG14427.1 - 0.78 10.0 0.0 0.78 10.0 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) zf-C2H2_assoc2 PF16624.5 EGG14429.1 - 9 7.4 9.4 1 10.4 1.5 2.9 3 0 0 3 3 3 0 Unstructured region upstream of a zinc-finger V-SNARE PF05008.15 EGG14430.1 - 0.27 11.6 7.7 1 9.8 0.0 3.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus HEAT_2 PF13646.6 EGG14432.1 - 0.014 15.7 0.0 0.052 13.9 0.0 1.9 1 1 0 1 1 1 0 HEAT repeats Adaptin_N PF01602.20 EGG14432.1 - 0.046 12.3 0.2 0.085 11.4 0.2 1.4 1 0 0 1 1 1 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 EGG14432.1 - 0.057 14.0 0.3 0.3 11.7 0.0 2.4 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGG14432.1 - 0.087 13.1 0.0 0.31 11.4 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat Med19 PF10278.9 EGG14432.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNase_H PF00075.24 EGG14434.1 - 5.9e-11 42.7 0.6 2.7e-09 37.3 0.4 2.8 2 0 0 2 2 2 1 RNase H PBECR3 PF18812.1 EGG14434.1 - 0.16 12.0 2.3 0.18 11.8 0.3 2.1 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 Ribonuc_L-PSP PF01042.21 EGG14436.1 - 4.2e-31 107.5 0.0 5.4e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4500 PF14937.6 EGG14436.1 - 0.015 15.3 0.2 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) Ammonium_transp PF00909.21 EGG14437.1 - 2.3e-109 365.7 25.9 2.6e-109 365.5 25.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Patatin PF01734.22 EGG14438.1 - 2e-08 34.7 0.2 4.3e-08 33.6 0.2 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase WW PF00397.26 EGG14438.1 - 0.00015 21.8 0.1 0.0004 20.4 0.1 1.8 1 0 0 1 1 1 1 WW domain SAGA-Tad1 PF12767.7 EGG14439.1 - 3.3e-42 144.8 5.9 3.3e-42 144.8 5.9 2.3 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit LAP1C PF05609.12 EGG14439.1 - 5.4 6.0 32.2 4.8 6.2 16.9 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_C92 PF05708.12 EGG14440.1 - 4.2e-06 26.9 0.0 2.7e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Glyco_hydro_16 PF00722.21 EGG14441.1 - 4e-05 23.1 0.2 4e-05 23.1 0.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Imm19 PF15563.6 EGG14441.1 - 0.057 12.9 0.2 0.092 12.2 0.2 1.3 1 1 0 1 1 1 0 Immunity protein 19 DUF3084 PF11283.8 EGG14441.1 - 0.14 12.1 0.9 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) Ost5 PF05251.12 EGG14444.1 - 3.5e-19 68.8 11.6 3.9e-19 68.7 11.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Phage_holin_3_6 PF07332.11 EGG14444.1 - 4.5 7.3 10.4 0.098 12.7 1.5 2.0 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PEP_mutase PF13714.6 EGG14445.1 - 2.9e-55 187.3 0.4 3.4e-55 187.1 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EGG14445.1 - 8.6e-15 54.2 0.2 1.7e-14 53.3 0.1 1.4 2 0 0 2 2 2 1 Isocitrate lyase family NCKAP5 PF15246.6 EGG14446.1 - 0.15 11.7 2.6 0.27 10.8 2.6 1.3 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein DUF3447 PF11929.8 EGG14447.1 - 0.022 14.7 2.4 0.88 9.6 0.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EGG14448.1 - 0.0032 18.0 0.1 0.012 16.2 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14448.1 - 0.01 16.4 0.2 4.8 7.9 0.0 3.0 2 1 0 2 2 2 0 Ankyrin repeats (many copies) UVR PF02151.19 EGG14450.1 - 0.013 15.2 0.6 0.013 15.2 0.6 3.5 3 0 0 3 3 3 0 UvrB/uvrC motif DUF501 PF04417.12 EGG14450.1 - 4.9 7.0 13.6 1.4 8.7 1.0 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF501) Mito_carr PF00153.27 EGG14451.1 - 6e-35 119.1 2.0 2e-19 69.3 0.6 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein Lig_chan-Glu_bd PF10613.9 EGG14451.1 - 0.11 12.7 0.0 0.93 9.7 0.0 2.0 2 0 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site ketoacyl-synt PF00109.26 EGG14452.1 - 3.3e-61 207.0 0.0 5.9e-61 206.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG14452.1 - 1.6e-47 162.6 0.0 2.9e-47 161.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGG14452.1 - 1.7e-35 121.6 0.1 8.8e-35 119.3 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGG14452.1 - 4.1e-26 92.0 0.0 1.5e-25 90.2 0.0 2.1 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGG14452.1 - 4e-25 88.7 0.0 6.7e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGG14452.1 - 1.5e-14 54.4 0.4 5.5e-14 52.6 0.4 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension FHA PF00498.26 EGG14452.1 - 1e-12 48.2 0.2 7.2e-12 45.5 0.0 2.7 2 0 0 2 2 2 1 FHA domain ADH_zinc_N_2 PF13602.6 EGG14452.1 - 6.9e-11 43.3 0.0 1e-09 39.5 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGG14452.1 - 5.1e-07 29.7 0.0 2e-06 27.8 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG14452.1 - 6.9e-07 29.1 0.0 2.1e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGG14452.1 - 4.5e-06 26.9 0.0 1.8e-05 25.0 0.0 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EGG14452.1 - 0.0051 16.3 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 EGG14452.1 - 0.0053 16.2 0.3 0.013 14.9 0.3 1.6 1 1 0 1 1 1 1 Thiolase, N-terminal domain Yop-YscD_cpl PF16697.5 EGG14452.1 - 0.02 15.2 0.0 0.076 13.3 0.0 1.9 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain adh_short_C2 PF13561.6 EGG14452.1 - 0.042 13.4 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PIG-L PF02585.17 EGG14453.1 - 9.3e-24 84.5 0.0 1.3e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF2719 PF10891.8 EGG14453.1 - 0.015 15.2 0.0 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2719) Pkinase PF00069.25 EGG14454.1 - 2.8e-24 85.9 0.0 5.6e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain DSPc PF00782.20 EGG14454.1 - 1.5e-23 83.1 0.0 5.3e-23 81.3 0.0 2.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pkinase_Tyr PF07714.17 EGG14454.1 - 1.9e-13 50.3 0.0 4e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PAZ PF02170.22 EGG14454.1 - 0.037 13.8 0.8 0.12 12.2 0.8 1.9 1 0 0 1 1 1 0 PAZ domain LRR_6 PF13516.6 EGG14455.1 - 1.5e-15 55.9 34.9 0.00028 20.7 0.6 10.4 10 0 0 10 10 10 5 Leucine Rich repeat LRR_8 PF13855.6 EGG14455.1 - 0.34 10.7 20.9 2.3 8.0 3.5 6.4 4 2 2 6 6 6 0 Leucine rich repeat F-box PF00646.33 EGG14455.1 - 0.5 10.3 6.7 30 4.6 0.2 4.0 4 0 0 4 4 4 0 F-box domain F-box-like PF12937.7 EGG14455.1 - 0.71 9.8 2.5 45 4.0 0.0 3.3 3 0 0 3 3 3 0 F-box-like CTP_synth_N PF06418.14 EGG14457.1 - 4.9e-125 416.2 0.1 6.4e-125 415.8 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EGG14457.1 - 2e-32 112.5 0.0 3.7e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CbiA PF01656.23 EGG14457.1 - 0.13 12.4 0.0 0.35 10.9 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAT PF03417.16 EGG14458.1 - 0.00019 21.2 0.0 0.0014 18.4 0.0 2.1 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase UPF0220 PF05255.11 EGG14459.1 - 5.6e-32 110.6 2.6 6.5e-32 110.4 2.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) ABC_tran PF00005.27 EGG14460.1 - 4.8e-25 88.7 0.0 9.5e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGG14460.1 - 4.7e-19 68.7 40.0 4.7e-19 68.7 40.0 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGG14460.1 - 1.9e-09 37.8 0.0 8.8e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG14460.1 - 0.012 15.0 0.7 2.3 7.6 0.0 3.3 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGG14460.1 - 0.1 12.4 0.2 0.24 11.2 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KdpD PF02702.17 EGG14460.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain AAA_23 PF13476.6 EGG14460.1 - 0.91 10.0 3.8 0.43 11.1 0.6 2.0 2 0 0 2 2 2 0 AAA domain CTP_transf_like PF01467.26 EGG14461.1 - 1.9e-45 154.6 0.0 3.4e-25 88.9 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 EGG14461.1 - 5.8e-06 26.3 4.2 0.62 9.9 0.5 3.8 3 1 0 3 3 3 3 FAD synthetase HIGH_NTase1_ass PF16581.5 EGG14461.1 - 0.092 12.7 0.9 1.2 9.1 0.1 2.9 3 1 1 4 4 4 0 Cytidyltransferase-related C-terminal region Ank_2 PF12796.7 EGG14462.1 - 1e-33 115.7 6.1 2.7e-12 47.1 0.0 5.1 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14462.1 - 4.9e-27 94.0 13.1 1.3e-06 28.9 0.0 8.0 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EGG14462.1 - 9.3e-27 92.3 14.0 1.1e-05 25.7 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EGG14462.1 - 5.5e-26 90.3 0.8 5.5e-06 26.5 0.0 7.1 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14462.1 - 1.4e-17 62.0 14.2 0.01 16.3 0.0 9.3 9 1 0 9 9 9 5 Ankyrin repeat F-box-like PF12937.7 EGG14462.1 - 1.1e-05 25.2 0.1 3e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like zf-TRAF PF02176.18 EGG14462.1 - 0.009 16.7 4.9 0.009 16.7 4.9 3.3 2 1 2 4 4 4 3 TRAF-type zinc finger Vault PF01505.18 EGG14463.1 - 1.6e-58 194.6 0.6 1.7e-13 50.5 0.0 5.4 6 0 0 6 6 6 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 EGG14463.1 - 9.5e-53 177.2 0.4 1.8e-52 176.4 0.4 1.5 1 0 0 1 1 1 1 Shoulder domain Vault_2 PF17794.1 EGG14463.1 - 3e-36 123.6 0.1 6.3e-23 80.9 0.0 2.7 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 EGG14463.1 - 2.8e-35 120.1 0.2 3e-31 107.3 0.0 3.2 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault_4 PF17796.1 EGG14463.1 - 6.6e-25 87.0 0.0 5.5e-23 80.8 0.0 3.4 3 0 0 3 3 3 1 Major Vault Protein repeat domain Vault PF01505.18 EGG14464.1 - 1.1e-58 195.2 0.4 1.2e-15 57.3 0.0 5.0 5 0 0 5 5 5 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 EGG14464.1 - 2.7e-45 153.2 0.0 6.1e-45 152.1 0.0 1.7 1 0 0 1 1 1 1 Shoulder domain Vault_2 PF17794.1 EGG14464.1 - 7.5e-36 122.3 0.0 8.4e-21 74.1 0.0 2.7 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 EGG14464.1 - 1.3e-34 118.0 0.5 2.3e-30 104.4 0.0 3.3 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault_4 PF17796.1 EGG14464.1 - 3.4e-21 75.1 0.0 4.5e-20 71.5 0.0 2.7 2 0 0 2 2 2 1 Major Vault Protein repeat domain DUF3584 PF12128.8 EGG14464.1 - 4.9 4.5 18.6 7 4.0 18.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2218 PF09981.9 EGG14464.1 - 5.2 7.5 6.4 1.8 9.0 2.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) Str_synth PF03088.16 EGG14467.1 - 3.8e-18 65.4 0.0 2.2e-16 59.8 0.1 3.3 2 1 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 EGG14467.1 - 6.5e-18 65.2 0.0 2e-17 63.6 0.0 1.8 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EGG14467.1 - 2e-06 27.5 0.2 6.7 6.9 0.0 5.1 5 0 0 5 5 5 3 NHL repeat Arylesterase PF01731.20 EGG14467.1 - 0.062 13.5 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Arylesterase LSM PF01423.22 EGG14468.1 - 3.2e-17 62.0 0.8 5.7e-17 61.2 0.4 1.6 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.6 EGG14468.1 - 0.0066 16.6 0.0 0.0097 16.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Keratin_2_head PF16208.5 EGG14468.1 - 0.33 11.1 35.8 0.44 10.7 35.8 1.2 1 0 0 1 1 1 0 Keratin type II head EGF_CA PF07645.15 EGG14469.1 - 8.4e-20 70.7 40.8 7e-09 35.8 6.8 7.8 8 0 0 8 8 8 3 Calcium-binding EGF domain TIG PF01833.24 EGG14469.1 - 1.3e-11 44.4 18.5 0.00011 22.3 2.1 4.6 4 0 0 4 4 4 3 IPT/TIG domain cEGF PF12662.7 EGG14469.1 - 3.3e-11 42.9 10.0 9.4e-08 31.9 0.4 6.8 6 1 0 6 6 6 4 Complement Clr-like EGF-like EGF PF00008.27 EGG14469.1 - 4.9e-11 42.7 76.8 0.00031 21.0 6.0 7.0 6 0 0 6 6 6 5 EGF-like domain FXa_inhibition PF14670.6 EGG14469.1 - 1.9e-05 24.8 8.1 1.9e-05 24.8 8.1 7.3 4 2 2 6 6 6 3 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 EGG14469.1 - 0.00011 22.5 86.0 0.0087 16.4 14.3 7.2 6 0 0 6 6 6 3 EGF-like domain hEGF PF12661.7 EGG14469.1 - 0.0006 20.3 13.1 0.0016 19.0 2.2 8.6 8 0 0 8 8 8 4 Human growth factor-like EGF EGF_3 PF12947.7 EGG14469.1 - 0.0099 16.1 9.1 0.0099 16.1 9.1 8.0 5 1 1 6 6 6 2 EGF domain AA_permease_2 PF13520.6 EGG14470.1 - 0.16 10.7 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease APG9 PF04109.16 EGG14471.1 - 5e-174 579.8 12.6 8e-174 579.1 12.6 1.3 1 0 0 1 1 1 1 Autophagy protein Apg9 RasGAP PF00616.19 EGG14471.1 - 6.3e-23 81.6 0.2 6.3e-23 81.6 0.2 3.9 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.18 EGG14471.1 - 2e-21 76.2 0.0 9.1e-21 74.0 0.0 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EGG14471.1 - 0.015 15.6 0.0 0.17 12.2 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) CLU PF13236.6 EGG14472.1 - 8.8e-59 199.0 0.0 1.9e-58 197.9 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGG14472.1 - 1.9e-07 31.3 0.0 1.9e-07 31.3 0.0 2.9 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 LRR_6 PF13516.6 EGG14472.1 - 0.0023 17.8 1.3 49 4.4 0.3 5.2 4 0 0 4 4 4 2 Leucine Rich repeat TPR_12 PF13424.6 EGG14473.1 - 1.2e-33 115.2 22.8 1.3e-12 47.8 1.9 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat DUF4062 PF13271.6 EGG14473.1 - 7.8e-15 55.0 0.0 3.9e-14 52.8 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4062) TPR_10 PF13374.6 EGG14473.1 - 7.5e-12 44.7 22.1 2.4e-05 24.1 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat NACHT PF05729.12 EGG14473.1 - 9.2e-08 32.2 0.0 1.6e-06 28.1 0.0 2.9 2 1 0 2 2 2 1 NACHT domain TPR_2 PF07719.17 EGG14473.1 - 4.4e-07 29.5 24.4 0.0038 17.2 0.3 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG14473.1 - 9.6e-07 28.4 22.7 0.00028 20.6 0.5 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat AAA_16 PF13191.6 EGG14473.1 - 1e-05 26.0 0.0 5.8e-05 23.5 0.0 2.4 2 0 0 2 2 1 1 AAA ATPase domain TPR_MalT PF17874.1 EGG14473.1 - 2.4e-05 23.9 5.4 0.0043 16.5 0.5 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 EGG14473.1 - 7.7e-05 22.6 23.6 0.0011 19.1 0.6 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TIG PF01833.24 EGG14473.1 - 0.0002 21.4 0.8 0.00084 19.4 0.8 2.1 1 0 0 1 1 1 1 IPT/TIG domain SNAP PF14938.6 EGG14473.1 - 0.00023 20.7 2.7 0.0042 16.6 1.0 2.5 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP BRCT PF00533.26 EGG14473.1 - 0.004 17.5 0.7 0.017 15.5 0.4 2.3 2 1 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain AAA_22 PF13401.6 EGG14473.1 - 0.0051 17.1 0.0 0.049 13.9 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGG14473.1 - 0.0063 16.0 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region Pet100 PF09803.9 EGG14473.1 - 0.016 15.7 0.8 0.2 12.2 0.3 2.8 2 0 0 2 2 2 0 Pet100 DUF2225 PF09986.9 EGG14473.1 - 0.018 14.8 5.5 0.28 10.9 0.1 3.6 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_11 PF13414.6 EGG14473.1 - 0.02 14.6 0.6 3.6 7.4 0.0 3.1 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 EGG14473.1 - 0.057 13.5 12.2 0.53 10.4 0.1 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGG14473.1 - 0.074 12.5 0.5 0.55 9.7 0.1 2.6 3 0 0 3 3 3 0 SHNi-TPR ATPase_2 PF01637.18 EGG14473.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.4 3 0 0 3 3 1 0 ATPase domain predominantly from Archaea TPR_16 PF13432.6 EGG14473.1 - 0.44 11.2 3.6 36 5.1 0.1 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat Asp_decarbox PF02261.16 EGG14474.1 - 0.0097 15.8 0.4 0.012 15.6 0.4 1.2 1 0 0 1 1 1 1 Aspartate decarboxylase Ank_2 PF12796.7 EGG14475.1 - 1.5e-10 41.5 3.9 2e-05 25.1 0.1 4.2 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG14475.1 - 2.1e-10 40.6 3.0 0.0083 16.4 0.1 5.6 2 1 4 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG14475.1 - 2.8e-08 34.1 2.2 0.0021 18.6 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14475.1 - 3e-05 24.1 4.0 26 5.8 0.0 6.7 6 1 1 7 7 7 1 Ankyrin repeat DUF5049 PF16468.5 EGG14475.1 - 0.00017 21.4 0.3 3.4 7.6 0.0 4.4 3 1 1 4 4 4 2 Domain of unknown function (DUF5049) CNOT1_HEAT PF16418.5 EGG14475.1 - 0.15 12.1 0.7 12 6.0 0.0 3.3 2 1 1 3 3 3 0 CCR4-NOT transcription complex subunit 1 HEAT repeat KR PF08659.10 EGG14477.1 - 3.8e-23 82.3 0.1 7.2e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 KR domain ADH_N PF08240.12 EGG14477.1 - 1.5e-06 28.0 0.2 1.8e-05 24.6 0.0 2.6 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Thioredoxin_13 PF18401.1 EGG14477.1 - 0.082 12.8 3.9 0.065 13.1 1.8 1.9 1 1 1 2 2 2 0 Thioredoxin-like domain DUF3876 PF12992.7 EGG14477.1 - 0.12 12.5 0.2 5.3 7.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) E3_UbLigase_EDD PF11547.8 EGG14477.1 - 0.79 9.5 5.1 0.42 10.4 1.7 2.2 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD Dicty_REP PF05086.12 EGG14479.1 - 0.00055 18.1 1.4 0.00055 18.1 1.4 1.5 2 0 0 2 2 2 1 Dictyostelium (Slime Mold) REP protein Mac PF12464.8 EGG14479.1 - 0.12 12.7 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 Maltose acetyltransferase Mucin PF01456.17 EGG14479.1 - 2.6 8.0 19.5 4.4 7.3 19.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein BRCT_2 PF16589.5 EGG14480.1 - 7e-19 68.0 0.4 1.7e-10 41.2 0.0 3.5 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG14480.1 - 1.3e-16 60.7 1.3 3.1e-07 30.7 0.1 3.4 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RAMA PF18755.1 EGG14480.1 - 2.4e-11 44.0 0.0 6.8e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated PTCB-BRCT PF12738.7 EGG14480.1 - 1.9e-05 24.5 0.6 0.00036 20.4 0.1 2.7 3 0 0 3 3 3 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 EGG14480.1 - 0.34 10.8 0.0 0.34 10.8 0.0 3.6 4 0 0 4 4 4 0 Regulator of Ty1 transposition protein 107 BRCT domain Ank_2 PF12796.7 EGG14481.1 - 2.2e-28 98.7 0.2 2.6e-18 66.4 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14481.1 - 7.1e-26 90.3 1.0 1.9e-14 53.8 0.1 5.3 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Bromodomain PF00439.25 EGG14481.1 - 9.5e-22 76.9 0.0 3.5e-21 75.1 0.0 2.1 1 0 0 1 1 1 1 Bromodomain Ank PF00023.30 EGG14481.1 - 1.2e-21 76.1 2.3 6e-05 23.3 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EGG14481.1 - 5.5e-20 69.3 0.4 0.00016 21.8 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EGG14481.1 - 2.1e-19 69.3 0.4 3e-09 36.9 0.2 3.7 1 1 1 3 3 3 3 Ankyrin repeats (many copies) BTB PF00651.31 EGG14481.1 - 1.2e-18 67.4 2.1 2.8e-18 66.1 0.1 2.8 3 0 0 3 3 2 1 BTB/POZ domain BET PF17035.5 EGG14481.1 - 2.6e-06 27.5 5.5 5.8e-05 23.2 5.5 3.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Cnd1 PF12717.7 EGG14481.1 - 6.2e-05 23.1 10.1 0.03 14.4 0.2 4.6 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGG14481.1 - 0.0049 17.0 0.1 11 6.6 0.0 4.8 6 0 0 6 6 5 1 HEAT repeat HEAT_2 PF13646.6 EGG14481.1 - 0.039 14.4 0.0 1.5 9.3 0.0 3.4 4 0 0 4 4 4 0 HEAT repeats MA3 PF02847.17 EGG14481.1 - 0.61 10.1 8.0 0.96 9.4 0.1 3.7 3 0 0 3 3 3 0 MA3 domain UQ_con PF00179.26 EGG14482.1 - 7.6e-20 71.0 0.1 9.4e-20 70.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Reticulon PF02453.17 EGG14483.1 - 7.5e-29 100.7 7.6 7.5e-29 100.7 7.6 1.8 2 0 0 2 2 2 1 Reticulon YtxH PF12732.7 EGG14483.1 - 0.0046 17.5 9.4 0.01 16.3 6.6 2.3 2 0 0 2 2 2 1 YtxH-like protein DUF883 PF05957.13 EGG14483.1 - 0.019 15.5 0.9 0.019 15.5 0.9 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 EGG14483.1 - 0.032 14.3 6.7 0.032 14.3 6.7 2.6 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Tektin PF03148.14 EGG14483.1 - 0.056 12.2 2.9 0.099 11.4 2.9 1.3 1 0 0 1 1 1 0 Tektin family COG2 PF06148.11 EGG14483.1 - 0.075 13.1 3.3 0.19 11.8 3.3 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Apolipoprotein PF01442.18 EGG14483.1 - 0.2 11.5 5.9 0.094 12.6 3.4 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain CdvA PF18822.1 EGG14483.1 - 0.26 11.1 9.4 0.068 13.0 5.9 1.8 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ACCA PF03255.14 EGG14483.1 - 2.5 8.0 4.7 4.4 7.2 4.7 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Laminin_II PF06009.12 EGG14483.1 - 3.7 7.6 9.6 1.1 9.3 4.5 2.3 3 0 0 3 3 3 0 Laminin Domain II DUF948 PF06103.11 EGG14483.1 - 5.1 7.4 14.7 0.23 11.7 4.1 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ribosomal_S5 PF00333.20 EGG14484.1 - 2.6e-14 52.9 1.1 4.6e-14 52.2 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Syntaxin_2 PF14523.6 EGG14484.1 - 1.1 9.7 5.7 0.35 11.3 0.3 2.7 2 1 0 2 2 2 0 Syntaxin-like protein DAAD PF18752.1 EGG14485.1 - 3.6e-70 237.1 0.2 5e-69 233.4 0.2 2.2 1 1 0 1 1 1 1 Dictyosteliid AID/APOBEC-like Deaminase N6-adenineMlase PF10237.9 EGG14485.1 - 0.038 13.8 1.8 0.074 12.9 1.8 1.6 1 1 0 1 1 1 0 Probable N6-adenine methyltransferase PP1c_bdg PF10488.9 EGG14485.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region DAAD PF18752.1 EGG14486.1 - 2.3e-79 267.3 0.3 2.2e-77 260.8 0.3 2.3 1 1 0 1 1 1 1 Dictyosteliid AID/APOBEC-like Deaminase DAAD PF18752.1 EGG14487.1 - 1.1e-105 353.7 0.7 1.9e-105 352.9 0.7 1.4 1 0 0 1 1 1 1 Dictyosteliid AID/APOBEC-like Deaminase NINJA_B PF16136.5 EGG14488.1 - 0.011 16.1 3.1 0.013 15.9 1.9 1.8 2 0 0 2 2 2 0 Putative nuclear localisation signal SPC25 PF06703.11 EGG14488.1 - 1.6 8.5 6.2 4.3 7.1 2.8 2.5 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) ATG16 PF08614.11 EGG14489.1 - 0.0045 17.2 2.9 0.0088 16.3 2.9 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Integrase_H2C2 PF17921.1 EGG14490.1 - 2.5e-14 53.1 0.5 5.4e-14 52.0 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 EGG14490.1 - 3.6e-05 24.0 0.1 0.00055 20.2 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF2321 PF10083.9 EGG14490.1 - 0.096 12.3 0.9 0.33 10.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-H2C2 PF09337.10 EGG14490.1 - 0.13 12.5 0.3 0.84 9.9 0.0 2.4 2 0 0 2 2 2 0 H2C2 zinc finger Retrotrans_gag PF03732.17 EGG14490.1 - 0.32 11.3 3.1 0.4 11.0 0.2 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein Patatin PF01734.22 EGG14491.1 - 0.0058 16.8 0.3 0.031 14.5 0.2 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase DUF4210 PF13915.6 EGG14492.1 - 0.056 14.0 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4210) 2Fe-2S_thioredx PF01257.19 EGG14492.1 - 0.065 13.1 0.8 0.11 12.4 0.8 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Peptidase_M16_C PF05193.21 EGG14494.1 - 3.4e-15 56.5 0.1 1.3e-11 44.8 0.0 3.6 3 2 0 3 3 3 2 Peptidase M16 inactive domain YL1 PF05764.13 EGG14494.1 - 0.0018 18.5 8.2 0.0032 17.6 8.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein M16C_assoc PF08367.11 EGG14494.1 - 0.0046 16.1 0.1 0.0046 16.1 0.1 2.2 2 1 0 2 2 1 1 Peptidase M16C associated SDA1 PF05285.12 EGG14494.1 - 0.0047 16.4 8.5 0.0047 16.4 8.5 1.7 2 0 0 2 2 2 1 SDA1 Nop14 PF04147.12 EGG14494.1 - 0.036 12.3 11.4 0.056 11.7 11.4 1.2 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 EGG14494.1 - 0.11 10.6 5.3 0.17 9.9 5.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 EGG14494.1 - 0.12 10.5 16.4 0.23 9.5 16.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi G0-G1_switch_2 PF15103.6 EGG14494.1 - 0.29 11.6 2.2 14 6.2 0.0 3.0 3 0 0 3 3 3 0 G0/G1 switch protein 2 CDC45 PF02724.14 EGG14494.1 - 0.32 9.2 8.9 0.5 8.6 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 EGG14494.1 - 0.54 9.4 8.6 0.42 9.8 5.7 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.6 EGG14494.1 - 1.8 8.2 5.8 4.3 7.0 5.8 1.6 1 0 0 1 1 1 0 FAM176 family PTPRCAP PF15713.5 EGG14494.1 - 2.1 8.6 12.3 4.2 7.6 12.3 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated ORC_WH_C PF18137.1 EGG14494.1 - 2.8 8.0 6.0 6.8 6.8 5.7 1.8 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal SspB PF04386.13 EGG14494.1 - 9.9 6.0 7.5 53 3.7 7.8 2.0 2 0 0 2 2 2 0 Stringent starvation protein B HSP20 PF00011.21 EGG14495.1 - 0.00051 20.1 0.0 0.00083 19.5 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HSP20 PF00011.21 EGG14496.1 - 2.2e-05 24.5 0.0 3.5e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family TK PF00265.18 EGG14497.1 - 1.6e-67 226.8 0.3 1.9e-67 226.6 0.3 1.1 1 0 0 1 1 1 1 Thymidine kinase ATPase_2 PF01637.18 EGG14497.1 - 0.16 11.8 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ribosomal_L40e PF01020.17 EGG14497.1 - 0.19 11.7 1.5 0.98 9.4 0.2 2.5 2 0 0 2 2 2 0 Ribosomal L40e family EF1G PF00647.19 EGG14498.1 - 2.1e-44 149.9 0.2 4.8e-44 148.8 0.2 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EGG14498.1 - 6.2e-17 61.7 0.1 6.2e-17 61.7 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG14498.1 - 2.4e-13 50.1 1.2 5.4e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGG14498.1 - 1.2e-09 38.5 0.1 9.4e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGG14498.1 - 8.6e-08 32.1 0.0 1.9e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGG14498.1 - 1.1e-06 28.8 0.0 2.3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGG14498.1 - 1.1e-05 25.5 0.0 3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 EGG14498.1 - 0.0076 16.6 0.0 0.025 14.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain DUF2868 PF11067.8 EGG14498.1 - 0.035 13.6 0.1 1.3 8.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) GST_C_6 PF17171.4 EGG14498.1 - 0.21 11.4 0.4 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain MMR_HSR1 PF01926.23 EGG14499.1 - 2.9e-22 78.9 0.0 1e-21 77.1 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG14499.1 - 3e-09 37.0 0.1 0.0042 17.0 0.0 3.0 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGG14499.1 - 3.7e-06 26.6 0.0 7.9e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGG14499.1 - 0.017 15.2 0.5 0.24 11.4 0.2 4.6 3 2 1 4 4 4 0 Dynamin family Roc PF08477.13 EGG14499.1 - 0.021 15.1 0.3 1.2 9.4 0.0 3.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGG14499.1 - 0.056 13.2 0.0 0.2 11.4 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pullulanase_Ins PF18494.1 EGG14500.1 - 0.092 13.2 0.1 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 Pullulanase Ins domain LRR_6 PF13516.6 EGG14500.1 - 6.2 7.1 5.7 92 3.5 0.2 4.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 EGG14500.1 - 7.4 6.4 13.5 0.9 9.4 1.2 3.5 3 0 0 3 3 3 0 Leucine rich repeat FNIP PF05725.12 EGG14501.1 - 1.3e-11 44.4 13.3 2.6e-07 30.7 0.1 6.7 8 0 0 8 8 8 3 FNIP Repeat DUF4515 PF14988.6 EGG14503.1 - 0.00031 20.6 30.1 0.011 15.5 21.1 3.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4515) Tup_N PF08581.10 EGG14503.1 - 0.0039 17.4 27.6 0.11 12.8 11.8 3.1 1 1 1 2 2 2 2 Tup N-terminal DUF3584 PF12128.8 EGG14503.1 - 0.0044 14.6 19.4 0.0056 14.3 19.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) zf-GRF PF06839.12 EGG14503.1 - 0.0056 16.7 0.7 0.012 15.6 0.7 1.6 1 0 0 1 1 1 1 GRF zinc finger AAA_23 PF13476.6 EGG14503.1 - 0.01 16.3 21.7 0.016 15.7 21.7 1.4 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.6 EGG14503.1 - 0.029 14.8 26.8 0.71 10.3 2.4 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Filament PF00038.21 EGG14503.1 - 0.091 12.3 26.6 0.22 11.0 15.7 2.1 1 1 1 2 2 2 0 Intermediate filament protein YabA PF06156.13 EGG14503.1 - 0.13 12.9 28.2 1.5 9.5 4.2 4.3 1 1 3 4 4 4 0 Initiation control protein YabA MnmE_helical PF12631.7 EGG14503.1 - 0.15 12.2 8.4 0.17 12.1 0.3 2.6 1 1 2 3 3 3 0 MnmE helical domain FAM184 PF15665.5 EGG14503.1 - 0.17 11.7 24.1 0.65 9.7 24.1 2.1 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Ribosomal_S17e PF00833.18 EGG14503.1 - 0.18 11.7 12.0 0.92 9.4 0.9 3.5 1 1 3 4 4 4 0 Ribosomal S17 MRPL52 PF18699.1 EGG14503.1 - 0.2 11.9 17.3 2.2 8.5 2.1 3.7 1 1 3 4 4 4 0 Mitoribosomal protein mL52 SHE3 PF17078.5 EGG14503.1 - 0.27 10.9 28.1 0.1 12.3 1.9 3.3 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 ECM11 PF15463.6 EGG14503.1 - 0.29 11.7 13.7 0.5 10.9 13.7 1.5 1 1 0 1 1 1 0 Extracellular mutant protein 11 HMMR_N PF15905.5 EGG14503.1 - 0.32 10.4 26.4 0.43 10.0 26.4 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal SOAR PF16533.5 EGG14503.1 - 0.4 10.7 11.1 0.24 11.4 7.7 2.3 1 1 1 2 2 2 0 STIM1 Orai1-activating region S_tail_recep_bd PF14928.6 EGG14503.1 - 0.69 10.6 4.5 6.9 7.4 0.3 2.8 1 1 2 3 3 3 0 Short tail fibre protein receptor-binding domain DUF1664 PF07889.12 EGG14503.1 - 0.79 9.8 11.9 0.26 11.3 4.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) MatP_C PF17414.2 EGG14503.1 - 1.1 9.6 19.4 5.1 7.4 1.2 4.5 2 1 3 5 5 5 0 MatP C-terminal ribbon-helix-helix domain Phage_Mu_Gam PF07352.12 EGG14503.1 - 2.2 8.2 20.8 0.21 11.5 5.0 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein TetR_C_24 PF17932.1 EGG14503.1 - 2.6 8.4 7.1 7.4 6.9 0.8 2.8 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain YPEB PF14620.6 EGG14503.1 - 3.5 6.9 19.2 0.49 9.7 3.5 2.6 1 1 2 3 3 3 0 YpeB sporulation PCRF PF03462.18 EGG14503.1 - 5 7.0 20.0 1.4 8.8 10.4 2.1 1 1 1 2 2 2 0 PCRF domain DUF763 PF05559.11 EGG14503.1 - 5.3 6.1 10.5 0.52 9.5 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF763) YfcL PF08891.11 EGG14503.1 - 5.8 7.3 7.4 26 5.3 0.4 3.1 2 1 2 4 4 4 0 YfcL protein ApoO PF09769.9 EGG14503.1 - 7.2 6.6 6.4 21 5.1 5.9 2.1 1 1 0 1 1 1 0 Apolipoprotein O EGF_Tenascin PF18720.1 EGG14504.1 - 4.8 7.3 10.1 12 6.0 10.1 1.7 1 0 0 1 1 1 0 Tenascin EGF domain MMACHC PF16690.5 EGG14505.1 - 3.7e-13 49.6 0.1 7.6e-13 48.6 0.1 1.5 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family Oxidored_FMN PF00724.20 EGG14507.1 - 8.9e-81 271.8 0.0 1.1e-80 271.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family G3P_antiterm PF04309.12 EGG14507.1 - 0.021 14.3 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator DUF5086 PF16985.5 EGG14507.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5086) Dus PF01207.17 EGG14507.1 - 0.16 11.1 0.1 0.82 8.7 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Ank_5 PF13857.6 EGG14508.1 - 1.8e-12 47.2 0.0 1.8e-12 47.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG14508.1 - 4.1e-09 36.9 0.0 1.4e-08 35.2 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14508.1 - 4e-08 33.6 0.1 1.4e-07 31.9 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14508.1 - 5.6e-06 26.3 0.7 5.1e-05 23.4 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EGG14508.1 - 5.5e-05 23.4 1.1 9.8e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Selenoprotein_S PF06936.11 EGG14508.1 - 0.14 11.9 0.6 0.39 10.5 0.6 1.7 1 0 0 1 1 1 0 Selenoprotein S (SelS) Conotoxin PF02950.17 EGG14509.1 - 0.032 15.3 0.0 0.13 13.3 0.0 2.0 1 0 0 1 1 1 0 Conotoxin Chlam_PMP PF02415.17 EGG14509.1 - 0.057 13.9 1.0 0.057 13.9 1.0 8.2 11 1 0 11 11 11 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat SelK_SelG PF10961.8 EGG14509.1 - 0.12 13.0 3.2 0.82 10.3 0.3 3.5 3 0 0 3 3 3 0 Selenoprotein SelK_SelG 2_5_RNA_ligase2 PF13563.6 EGG14510.1 - 3.5e-34 117.9 0.1 4.5e-34 117.6 0.1 1.0 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 EGG14510.1 - 6.3e-07 29.5 0.1 0.0039 17.3 0.0 2.4 2 0 0 2 2 2 2 LigT like Phosphoesterase AKAP7_NLS PF10469.9 EGG14510.1 - 0.00024 21.0 0.1 0.00032 20.7 0.1 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain ABC_tran_CTD PF16326.5 EGG14510.1 - 0.033 14.4 0.0 2.3 8.5 0.0 2.7 4 0 0 4 4 4 0 ABC transporter C-terminal domain ATG_C PF09333.11 EGG14511.1 - 6.2e-22 77.8 0.0 1.5e-20 73.4 0.0 2.9 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EGG14511.1 - 1.6e-09 37.9 0.1 1.6e-09 37.9 0.1 4.3 4 1 0 4 4 4 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 EGG14511.1 - 8.5e-07 28.9 0.4 8.5e-07 28.9 0.4 3.2 3 1 1 4 4 4 1 Vacuolar-sorting-associated 13 protein C-terminal PAXNEB PF05625.11 EGG14512.1 - 5.1e-95 318.7 0.5 6.3e-95 318.4 0.5 1.0 1 0 0 1 1 1 1 PAXNEB protein HAT PF02184.16 EGG14513.1 - 3e-26 91.1 66.0 6.6e-09 35.6 0.3 14.0 14 1 0 14 14 14 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EGG14513.1 - 1.3e-19 69.2 5.3 0.0015 19.2 0.1 10.0 7 4 4 11 11 9 5 Tetratricopeptide repeat Suf PF05843.14 EGG14513.1 - 5.4e-15 56.2 26.8 0.00081 19.5 0.1 8.5 1 1 5 7 7 7 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 EGG14513.1 - 5.5e-13 48.3 0.1 0.085 13.3 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG14513.1 - 8.8e-09 35.8 0.2 0.061 13.9 0.0 5.9 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG14513.1 - 1.4e-05 25.4 6.3 5.2 7.9 0.1 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG14513.1 - 5.6e-05 23.0 0.8 36 4.9 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG14513.1 - 0.00013 21.8 5.2 36 4.8 0.1 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGG14513.1 - 0.00016 21.7 21.7 0.14 12.2 5.2 6.6 6 1 0 6 6 6 2 Mad3/BUB1 homology region 1 Wzy_C_2 PF11846.8 EGG14513.1 - 0.0013 18.7 0.7 0.0093 15.9 0.1 2.6 2 0 0 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal TPR_12 PF13424.6 EGG14513.1 - 0.0047 17.2 0.5 2.6 8.4 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG14513.1 - 0.023 14.8 0.6 9.3 6.5 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Babuvirus_MP PF07234.11 EGG14513.1 - 0.095 12.9 0.1 8.7 6.5 0.0 3.6 3 1 1 4 4 4 0 Movement and RNA silencing protein QIL1 PF15884.5 EGG14513.1 - 0.14 12.7 1.9 3.2 8.4 0.0 3.7 3 0 0 3 3 3 0 MICOS complex subunit MIC13, QIL1 TPR_10 PF13374.6 EGG14513.1 - 1 9.3 9.7 0.73 9.8 0.2 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat FNIP PF05725.12 EGG14514.1 - 1.5e-09 37.8 28.8 0.00044 20.4 0.9 8.1 7 1 3 10 10 10 5 FNIP Repeat NUDIX PF00293.28 EGG14515.1 - 9.8e-11 41.8 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain AAR2 PF05282.11 EGG14515.1 - 0.065 12.6 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 AAR2 protein DUF5553 PF17707.1 EGG14517.1 - 0.0083 15.6 0.0 0.0092 15.4 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5553) Stn1 PF10451.9 EGG14517.1 - 0.06 12.3 4.4 0.064 12.2 4.4 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 LMBR1 PF04791.16 EGG14517.1 - 0.33 9.8 3.6 0.4 9.5 3.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2681 PF10883.8 EGG14517.1 - 0.77 10.2 9.4 0.043 14.2 3.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Presenilin PF01080.17 EGG14517.1 - 6.1 5.5 7.7 7.3 5.2 7.7 1.1 1 0 0 1 1 1 0 Presenilin SET PF00856.28 EGG14518.1 - 2.7e-10 40.9 1.0 5.7e-10 39.8 0.2 2.0 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 EGG14518.1 - 3.2e-07 29.9 5.6 0.095 12.9 1.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGG14518.1 - 1.2e-05 24.9 12.7 0.34 10.8 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGG14518.1 - 0.0082 15.8 3.0 0.3 10.8 0.2 2.9 2 0 0 2 2 2 1 TPR repeat zf-MYND PF01753.18 EGG14518.1 - 0.014 15.5 10.2 0.014 15.5 10.2 2.5 3 0 0 3 3 3 0 MYND finger TPR_8 PF13181.6 EGG14518.1 - 0.015 15.4 8.7 0.43 10.9 0.7 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG14518.1 - 0.019 15.2 1.1 2.3 8.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SAF PF08666.12 EGG14518.1 - 0.072 13.7 0.0 34 5.2 0.0 3.6 4 0 0 4 4 4 0 SAF domain MIT PF04212.18 EGG14518.1 - 0.42 10.7 4.3 1.3 9.1 0.1 3.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain tRNA_U5-meth_tr PF05958.11 EGG14519.1 - 3.4e-20 72.4 0.2 6.9e-20 71.3 0.0 1.6 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EGG14519.1 - 1e-07 31.8 0.6 2.1e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG14519.1 - 1.8e-06 28.6 0.1 1.2e-05 25.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG14519.1 - 8.2e-05 22.0 0.7 0.0037 16.6 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGG14519.1 - 0.0013 18.3 0.6 0.019 14.5 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase small domain Biotin_lipoyl_2 PF13533.6 EGG14519.1 - 0.0016 18.2 0.0 0.0042 16.9 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like DREV PF05219.12 EGG14519.1 - 0.0018 17.4 0.1 0.0049 16.0 0.0 1.7 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_11 PF08241.12 EGG14519.1 - 0.0019 18.8 0.1 0.0079 16.8 0.1 2.1 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGG14519.1 - 0.0079 15.9 0.0 0.07 12.8 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 EGG14519.1 - 0.011 15.2 0.0 0.033 13.7 0.0 1.8 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_15 PF09445.10 EGG14519.1 - 0.014 15.0 0.1 0.03 13.9 0.1 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 EGG14519.1 - 0.015 15.0 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EGG14519.1 - 0.018 14.9 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGG14519.1 - 0.023 15.4 5.5 0.74 10.6 0.0 2.9 3 0 0 3 3 2 0 Methyltransferase domain UPF0020 PF01170.18 EGG14519.1 - 0.084 12.5 0.1 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Secretin_N_2 PF07655.13 EGG14519.1 - 6.9 7.3 14.2 0.54 10.8 6.0 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain Rhomboid PF01694.22 EGG14520.1 - 1.9e-34 118.8 14.5 3.4e-34 118.0 14.5 1.4 1 0 0 1 1 1 1 Rhomboid family SUIM_assoc PF16619.5 EGG14520.1 - 0.00023 21.2 2.2 0.0028 17.7 0.0 2.3 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 ADK PF00406.22 EGG14521.1 - 1.3e-47 161.7 0.0 1.7e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGG14521.1 - 4.3e-25 88.7 0.0 6.3e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EGG14521.1 - 2.8e-15 56.0 0.0 7.4e-15 54.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EGG14521.1 - 1.3e-06 29.0 0.0 2.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG14521.1 - 1.8e-05 24.9 0.0 3.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGG14521.1 - 0.031 14.0 0.3 4.3 7.0 0.1 2.4 1 1 0 2 2 2 0 Thymidylate kinase Cytidylate_kin PF02224.18 EGG14521.1 - 0.06 13.1 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase NUFIP1 PF10453.9 EGG14521.1 - 0.075 12.9 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF5462 PF17547.2 EGG14522.1 - 0.098 12.0 0.3 0.22 10.9 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5462) DUF5462 PF17547.2 EGG14523.1 - 0.15 11.4 0.3 0.3 10.4 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5462) Na_H_Exchanger PF00999.21 EGG14524.1 - 1.3e-60 205.2 41.6 2.1e-60 204.6 41.6 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 EGG14524.1 - 8.3e-05 23.1 0.0 0.069 13.7 0.0 2.7 2 1 0 2 2 2 2 Universal stress protein family HlyD PF00529.20 EGG14524.1 - 0.13 12.2 0.0 12 5.9 0.0 2.8 2 0 0 2 2 2 0 HlyD membrane-fusion protein of T1SS ETRAMP PF09716.10 EGG14524.1 - 0.21 11.7 6.7 0.85 9.7 1.5 3.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Orf78 PF06024.12 EGG14524.1 - 0.73 10.2 3.5 0.97 9.8 0.6 2.8 2 0 0 2 2 2 0 Orf78 (ac78) MscS_TM PF12794.7 EGG14524.1 - 1.2 7.9 15.2 0.051 12.4 7.4 2.5 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF624 PF04854.14 EGG14524.1 - 9.9 6.4 12.3 0.18 11.9 1.2 3.7 3 1 1 4 4 4 0 Protein of unknown function, DUF624 Ank_3 PF13606.6 EGG14525.1 - 0.017 15.6 0.0 0.99 10.2 0.0 3.6 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 EGG14525.1 - 0.059 14.0 0.0 0.27 11.9 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) DUF4470 PF14737.6 EGG14527.1 - 3.5e-10 39.9 0.0 1.2e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 EGG14527.1 - 1.5e-05 24.5 0.0 3.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_19 PF14559.6 EGG14527.1 - 0.00022 21.6 0.1 0.00069 20.1 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG14527.1 - 0.00066 19.4 1.0 0.23 11.3 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG14527.1 - 0.0022 17.9 0.4 0.081 13.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG14527.1 - 0.0041 17.0 1.0 1.7 8.8 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG14527.1 - 0.04 14.1 0.2 0.1 12.8 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EGG14527.1 - 0.12 12.6 2.2 0.21 11.9 0.4 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG14527.1 - 0.17 12.2 0.1 1.5 9.1 0.1 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat DNA_pol3_theta PF06440.11 EGG14528.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, theta subunit Chibby PF14645.6 EGG14528.1 - 0.67 10.4 4.1 9.5 6.7 4.1 2.3 1 1 0 1 1 1 0 Chibby family Linker_histone PF00538.19 EGG14529.1 - 0.069 13.5 0.1 21 5.6 0.0 3.1 3 0 0 3 3 3 0 linker histone H1 and H5 family DUF1730 PF08331.10 EGG14529.1 - 0.11 12.4 0.2 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) MRF_C1 PF13887.6 EGG14530.1 - 0.11 11.7 0.0 0.33 10.1 0.0 1.8 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 MKT1_C PF12246.8 EGG14532.1 - 0.01 15.1 1.2 0.01 15.1 1.2 1.6 1 1 1 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication Hamartin PF04388.12 EGG14532.1 - 0.42 9.2 14.1 0.44 9.1 14.1 1.0 1 0 0 1 1 1 0 Hamartin protein DltD PF04914.12 EGG14532.1 - 0.62 9.4 14.1 0.75 9.1 14.1 1.1 1 0 0 1 1 1 0 DltD protein ORC6 PF05460.13 EGG14532.1 - 1.2 8.4 21.8 1.4 8.1 21.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Med13_C PF06333.12 EGG14532.1 - 1.5 8.0 8.4 1.8 7.8 8.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Mitofilin PF09731.9 EGG14532.1 - 2.2 7.0 18.5 2.4 6.9 18.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF5427 PF10310.9 EGG14532.1 - 2.7 6.8 23.1 3.6 6.5 23.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) GET2 PF08690.10 EGG14532.1 - 4 7.0 13.5 5.9 6.5 13.5 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Peptidase_S64 PF08192.11 EGG14532.1 - 5.2 5.4 18.0 6 5.2 18.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 ASD2 PF08687.11 EGG14532.1 - 6 6.3 13.6 7.9 5.9 13.6 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 TMPIT PF07851.13 EGG14532.1 - 6.2 6.0 7.2 7.4 5.7 7.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4604 PF15377.6 EGG14532.1 - 6.8 7.1 25.5 10 6.5 25.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SOBP PF15279.6 EGG14532.1 - 9.6 6.7 14.7 12 6.4 14.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_M20 PF01546.28 EGG14533.1 - 1.1e-18 67.7 0.0 1e-17 64.5 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGG14533.1 - 2.7e-14 53.0 0.0 5.9e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain NTP_transferase PF00483.23 EGG14534.1 - 5.7e-51 173.5 0.0 7.5e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EGG14534.1 - 5.6e-09 36.6 0.0 7e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EGG14534.1 - 6.5e-09 35.2 6.3 3.1e-06 26.7 0.4 3.6 2 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EGG14534.1 - 0.052 11.7 0.3 0.67 8.0 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) DUF257 PF03192.13 EGG14534.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 Hexapep_2 PF14602.6 EGG14534.1 - 4.2 7.2 6.8 3.1 7.6 0.3 3.7 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase DUF2163 PF09931.9 EGG14535.1 - 0.065 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) tRNA-synt_2 PF00152.20 EGG14536.1 - 6.3e-80 268.6 0.1 1e-79 267.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGG14536.1 - 1.1e-13 50.9 0.1 2.8e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGG14536.1 - 3.4e-08 33.3 0.2 0.00014 21.4 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) BUD22 PF09073.10 EGG14537.1 - 0.11 11.8 29.2 0.18 11.1 29.2 1.2 1 0 0 1 1 1 0 BUD22 Glutaredoxin2_C PF04399.13 EGG14537.1 - 0.13 12.0 0.5 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain IBB PF01749.20 EGG14537.1 - 3.2 8.3 16.6 0.69 10.4 2.5 2.8 3 0 0 3 3 3 0 Importin beta binding domain PPP4R2 PF09184.11 EGG14537.1 - 3.2 7.3 38.5 2.9 7.4 22.8 2.1 2 0 0 2 2 2 0 PPP4R2 Cwf_Cwc_15 PF04889.12 EGG14537.1 - 9.1 5.9 39.8 17 5.1 39.8 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Redoxin PF08534.10 EGG14538.1 - 0.092 12.5 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Redoxin RRN3 PF05327.11 EGG14539.1 - 0.0062 15.1 18.2 0.0067 15.0 18.2 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 EGG14539.1 - 0.2 11.0 15.1 0.24 10.7 15.1 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EGG14539.1 - 0.34 10.3 23.3 0.44 9.9 23.3 1.0 1 0 0 1 1 1 0 SDA1 Merozoite_SPAM PF07133.11 EGG14539.1 - 0.54 10.2 31.0 0.75 9.8 31.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop14 PF04147.12 EGG14539.1 - 0.55 8.4 22.5 0.66 8.1 22.5 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGG14539.1 - 2.7 6.2 14.6 3.1 6.0 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 EGG14539.1 - 5.6 5.4 24.9 6.2 5.3 24.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF913 PF06025.12 EGG14539.1 - 6.1 5.7 6.0 7.9 5.4 6.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 EGG14539.1 - 8.7 5.7 16.1 9.6 5.5 16.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BUD22 PF09073.10 EGG14540.1 - 0.039 13.3 11.4 0.0098 15.3 8.0 1.7 2 0 0 2 2 2 0 BUD22 Ribosomal_60s PF00428.19 EGG14540.1 - 0.068 13.8 4.4 0.28 11.8 4.4 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Neur_chan_memb PF02932.16 EGG14540.1 - 0.31 11.1 4.2 0.14 12.2 1.2 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RRN3 PF05327.11 EGG14540.1 - 0.41 9.1 3.9 0.67 8.4 3.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FYDLN_acid PF09538.10 EGG14540.1 - 0.42 11.3 10.2 0.29 11.8 6.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) BSP_II PF05432.11 EGG14540.1 - 9.7 5.8 12.8 22 4.6 12.8 1.6 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) API5 PF05918.11 EGG14541.1 - 0.0039 16.1 0.8 0.008 15.0 0.3 1.7 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) DUF3963 PF13124.6 EGG14541.1 - 0.12 12.4 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) LRR_8 PF13855.6 EGG14542.1 - 0.031 14.1 13.6 0.087 12.6 3.1 4.8 4 1 1 5 5 5 0 Leucine rich repeat DUF3042 PF11240.8 EGG14542.1 - 0.045 13.8 0.2 0.094 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) EGF_2 PF07974.13 EGG14542.1 - 0.24 11.8 26.2 0.77 10.2 7.8 2.7 2 0 0 2 2 2 0 EGF-like domain ketoacyl-synt PF00109.26 EGG14543.1 - 7e-78 261.7 0.0 1.5e-77 260.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 EGG14543.1 - 3.1e-45 154.3 0.0 1.4e-44 152.2 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein Acyl_transf_1 PF00698.21 EGG14543.1 - 3.9e-44 151.4 0.0 9e-44 150.3 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGG14543.1 - 2.2e-40 137.4 0.5 3.5e-38 130.3 0.1 3.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGG14543.1 - 6e-37 127.3 0.4 1.6e-35 122.6 0.3 2.4 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGG14543.1 - 4.7e-27 95.0 0.0 7.7e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGG14543.1 - 3.8e-15 56.3 3.4 4.4e-15 56.1 0.3 2.8 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGG14543.1 - 1.5e-08 35.8 0.0 9.4e-08 33.2 0.0 2.5 3 0 0 3 3 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 EGG14543.1 - 2.7e-08 33.5 0.1 1.1e-06 28.3 0.0 2.9 3 0 0 3 3 3 1 Thiolase, N-terminal domain PP-binding PF00550.25 EGG14543.1 - 1.2e-06 28.8 0.1 3.1e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EGG14543.1 - 1.9e-05 24.5 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 EGG14543.1 - 0.00093 18.7 0.0 0.0023 17.4 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG14543.1 - 0.0048 15.9 0.1 0.016 14.3 0.1 1.9 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KxDL PF10241.9 EGG14543.1 - 0.005 17.1 1.9 0.01 16.1 0.5 2.4 2 0 0 2 2 1 1 Uncharacterized conserved protein UNC-93 PF05978.16 EGG14543.1 - 0.046 13.4 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Methyltransf_11 PF08241.12 EGG14543.1 - 0.1 13.2 0.1 0.74 10.5 0.0 2.6 3 0 0 3 3 2 0 Methyltransferase domain Sec23_trunk PF04811.15 EGG14544.1 - 2.1e-44 152.0 0.0 3e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGG14544.1 - 2.1e-21 75.7 0.1 4.2e-21 74.7 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGG14544.1 - 2e-17 63.7 0.0 3.7e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGG14544.1 - 5.8e-13 48.6 3.4 1.7e-12 47.2 3.4 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGG14544.1 - 1.6e-07 31.2 0.1 5.3e-07 29.5 0.1 1.9 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L4 PF00573.22 EGG14545.1 - 1.2e-35 122.9 0.2 1.2e-35 122.9 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EGG14545.1 - 6.1e-25 87.1 1.4 7.1e-23 80.5 0.7 2.3 2 0 0 2 2 2 2 60S ribosomal protein L4 C-terminal domain Kelch_1 PF01344.25 EGG14546.1 - 7.6e-40 134.3 18.1 8.5e-08 31.7 0.0 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 EGG14546.1 - 1.6e-38 130.2 9.9 2.9e-08 33.8 0.1 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 EGG14546.1 - 3.2e-38 129.5 16.2 4.1e-10 39.5 0.1 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EGG14546.1 - 1.1e-37 127.0 18.6 5.6e-07 29.6 0.1 7.4 6 1 1 7 7 7 6 Kelch motif Kelch_2 PF07646.15 EGG14546.1 - 1.8e-32 110.1 20.4 1.5e-05 24.8 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EGG14546.1 - 3.2e-30 103.6 11.3 3.2e-06 27.0 0.0 7.0 7 0 0 7 7 7 6 Kelch motif SAM_2 PF07647.17 EGG14546.1 - 3.7e-11 43.0 0.1 1.6e-10 40.9 0.1 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGG14546.1 - 7.6e-11 42.3 0.1 2.5e-10 40.6 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 EGG14546.1 - 0.011 15.7 0.3 0.029 14.3 0.1 1.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) TFIIA PF03153.13 EGG14546.1 - 0.49 10.3 18.7 1.2 9.0 3.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Menin PF05053.13 EGG14546.1 - 2 6.7 10.3 3.1 6.0 10.3 1.2 1 0 0 1 1 1 0 Menin MINDY_DUB PF04424.13 EGG14548.1 - 1.5e-25 89.5 0.0 2.8e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase RuvA_C PF07499.13 EGG14548.1 - 0.083 13.4 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 RuvA, C-terminal domain IucA_IucC PF04183.12 EGG14549.1 - 2.8e-46 158.0 0.0 4.3e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 EGG14549.1 - 1.5e-12 48.2 0.2 1e-11 45.6 0.2 2.4 1 1 1 2 2 2 1 Ferric iron reductase FhuF-like transporter IucA_IucC PF04183.12 EGG14550.1 - 1.4e-46 159.0 0.0 2.1e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 EGG14550.1 - 1.1e-08 35.6 0.0 2.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter EGF_2 PF07974.13 EGG14550.1 - 4e-05 23.9 12.2 0.00011 22.5 12.2 1.8 1 0 0 1 1 1 1 EGF-like domain DUF3844 PF12955.7 EGG14550.1 - 0.0053 16.9 1.3 0.0053 16.9 1.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) hEGF PF12661.7 EGG14550.1 - 0.0059 17.2 11.7 0.021 15.4 11.7 2.1 1 0 0 1 1 1 1 Human growth factor-like EGF I-EGF_1 PF18372.1 EGG14550.1 - 0.0088 16.1 8.3 0.02 15.0 8.3 1.6 1 0 0 1 1 1 1 Integrin beta epidermal growth factor like domain 1 EB PF01683.18 EGG14550.1 - 0.01 16.1 4.2 0.027 14.8 4.2 1.7 1 0 0 1 1 1 0 EB module EGF PF00008.27 EGG14550.1 - 0.01 16.1 8.7 0.043 14.1 8.7 2.2 1 0 0 1 1 1 0 EGF-like domain LRR_8 PF13855.6 EGG14550.1 - 0.023 14.4 3.4 7.2 6.5 0.8 4.1 3 1 0 4 4 4 0 Leucine rich repeat T4SS_CagC PF16943.5 EGG14550.1 - 0.032 14.4 0.2 0.069 13.3 0.2 1.5 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system LRR19-TM PF15176.6 EGG14550.1 - 0.076 13.0 0.9 0.25 11.4 0.9 1.8 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain EGF_CA PF07645.15 EGG14550.1 - 3.1 8.1 11.6 9.9 6.5 11.6 1.9 1 0 0 1 1 1 0 Calcium-binding EGF domain IucA_IucC PF04183.12 EGG14551.1 - 3.1e-49 167.7 0.0 4.6e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 EGG14551.1 - 1.9e-11 44.6 0.0 4.5e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter Glyco_hydro_28 PF00295.17 EGG14552.1 - 7.8e-34 117.2 0.4 1.1e-32 113.4 0.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EGG14552.1 - 4.6e-05 23.3 17.9 0.00052 19.9 1.0 3.4 2 1 1 3 3 3 2 Right handed beta helix region Kelch_1 PF01344.25 EGG14552.1 - 0.092 12.3 0.2 14 5.4 0.0 3.0 3 0 0 3 3 3 0 Kelch motif DUF21 PF01595.20 EGG14553.1 - 5.6e-35 120.6 2.3 9.3e-35 119.9 2.3 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EGG14553.1 - 0.00019 21.8 0.1 0.9 10.0 0.1 2.7 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 EGG14553.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain NOA36 PF06524.12 EGG14553.1 - 0.37 10.1 6.6 0.6 9.4 6.6 1.2 1 0 0 1 1 1 0 NOA36 protein Cornichon PF03311.14 EGG14554.1 - 7e-34 116.8 11.4 8.7e-34 116.5 11.4 1.1 1 0 0 1 1 1 1 Cornichon protein DUF4013 PF13197.6 EGG14554.1 - 0.34 10.7 11.5 0.96 9.3 11.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4013) PUF PF00806.19 EGG14555.1 - 3e-66 215.5 23.8 4.6e-10 38.6 0.7 8.7 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Ribosomal_S10 PF00338.22 EGG14557.1 - 4.5e-23 81.3 0.0 5.7e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e NYN PF01936.18 EGG14558.1 - 2.1e-22 80.2 0.1 2.1e-22 80.2 0.1 3.6 3 1 0 3 3 3 1 NYN domain AMPK1_CBM PF16561.5 EGG14558.1 - 1.5e-17 63.6 1.8 2.7e-13 49.9 0.4 5.0 5 1 1 6 6 6 2 Glycogen recognition site of AMP-activated protein kinase OHA PF14418.6 EGG14558.1 - 2.8e-17 62.3 1.9 6.5e-17 61.1 0.0 2.7 2 0 0 2 2 2 1 OST-HTH Associated domain SNase PF00565.17 EGG14559.1 - 7.7e-48 161.5 9.2 3e-14 53.4 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EGG14559.1 - 2.5e-20 72.7 0.0 5.5e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Tudor_2 PF18104.1 EGG14559.1 - 0.0012 18.4 0.5 0.0038 16.9 0.5 1.9 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain Agenet PF05641.12 EGG14559.1 - 0.0036 17.7 0.2 0.022 15.2 0.2 2.4 1 0 0 1 1 1 1 Agenet domain Tudor_3 PF18115.1 EGG14559.1 - 0.01 15.7 0.3 0.025 14.4 0.3 1.7 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain LIME1 PF15332.6 EGG14560.1 - 0.053 13.1 0.0 0.057 13.0 0.0 1.1 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 zf-HIT PF04438.16 EGG14561.1 - 7.1e-06 25.8 10.1 1.1e-05 25.2 10.1 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EGG14561.1 - 1.8 8.7 12.3 4.9 7.3 12.3 1.8 1 0 0 1 1 1 0 MYND finger DUF3439 PF11921.8 EGG14561.1 - 7.8 6.5 10.3 4.4 7.3 7.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CAP_N PF01213.19 EGG14562.1 - 0.33 10.4 3.0 0.46 9.9 3.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3337 PF11816.8 EGG14563.1 - 2e-28 99.4 0.0 2e-28 99.4 0.0 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EGG14563.1 - 4.4e-22 78.0 24.4 1.1e-06 29.3 0.1 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG14563.1 - 3.2e-09 37.0 0.8 0.00062 20.0 0.0 3.7 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG14563.1 - 0.00068 18.7 3.5 0.11 11.4 0.0 2.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RAWUL PF16207.5 EGG14563.1 - 0.0011 19.6 0.0 0.0033 18.0 0.0 1.9 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Peptidase_S55 PF05580.12 EGG14563.1 - 0.039 13.9 0.0 0.039 13.9 0.0 2.2 3 0 0 3 3 3 0 SpoIVB peptidase S55 Inositol_P PF00459.25 EGG14563.1 - 0.072 12.6 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Inositol monophosphatase family Corazonin PF17308.2 EGG14564.1 - 0.013 15.9 6.0 0.013 15.9 6.0 3.8 3 1 0 3 3 3 0 Pro-corazonin DUF687 PF05095.12 EGG14566.1 - 0.00044 18.9 0.1 0.0011 17.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF687) Ank_2 PF12796.7 EGG14567.1 - 5.2e-13 49.4 8.8 1.1e-07 32.3 0.8 2.8 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14567.1 - 1.4e-07 31.9 2.4 8.5e-05 23.0 0.1 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG14567.1 - 3.1e-07 30.5 2.3 0.03 14.6 0.0 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14567.1 - 5.4e-07 29.4 1.3 6.4 7.7 0.0 5.4 5 1 1 6 6 6 3 Ankyrin repeat Bud13 PF09736.9 EGG14568.1 - 2.5e-34 118.8 30.1 2.5e-34 118.8 30.1 4.2 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex YtpI PF14007.6 EGG14569.1 - 0.25 11.5 1.7 0.25 11.5 0.6 1.6 2 0 0 2 2 2 0 YtpI-like protein Ank_2 PF12796.7 EGG14570.1 - 9.4e-20 71.0 7.4 2e-08 34.7 0.5 5.3 3 2 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14570.1 - 9.4e-14 51.6 10.7 9e-05 23.0 0.1 9.1 8 2 3 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14570.1 - 1e-10 40.9 7.6 1.5 9.7 0.0 9.3 11 0 0 11 11 11 3 Ankyrin repeat Ank_5 PF13857.6 EGG14570.1 - 1.2e-06 28.7 2.6 0.59 10.5 0.1 6.9 6 2 2 8 8 8 2 Ankyrin repeats (many copies) Ank PF00023.30 EGG14570.1 - 0.11 13.0 10.0 1.2 9.7 0.4 6.2 6 1 0 6 6 6 0 Ankyrin repeat DUF4611 PF15387.6 EGG14570.1 - 1.7 8.9 5.5 2.9 8.2 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) PRP1_N PF06424.12 EGG14571.1 - 1e-47 162.3 0.8 2.2e-47 161.2 0.8 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EGG14571.1 - 1.2e-19 69.2 6.4 0.00035 21.2 0.0 8.8 4 3 5 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGG14571.1 - 3.9e-12 46.5 1.0 0.45 11.0 0.0 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGG14571.1 - 7.3e-06 25.7 0.0 0.099 12.8 0.0 5.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG14571.1 - 3.7e-05 24.3 0.8 0.0043 17.7 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG14571.1 - 0.00013 22.1 2.0 5.6 7.6 0.0 6.6 8 0 0 8 8 7 1 Tetratricopeptide repeat Suf PF05843.14 EGG14571.1 - 0.0041 17.1 8.1 1.5 8.7 0.1 4.3 5 0 0 5 5 5 1 Suppressor of forked protein (Suf) Wzy_C_2 PF11846.8 EGG14571.1 - 0.0054 16.7 0.3 0.14 12.0 0.0 2.9 2 0 0 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal TPR_12 PF13424.6 EGG14571.1 - 0.015 15.6 0.1 0.27 11.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGG14571.1 - 0.035 14.3 0.0 98 3.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DinB PF05163.12 EGG14571.1 - 0.072 13.0 1.9 0.22 11.4 1.1 2.1 2 0 0 2 2 2 0 DinB family TPR_6 PF13174.6 EGG14571.1 - 0.09 13.5 0.0 20 6.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat AhpC-TSA PF00578.21 EGG14572.1 - 2.3e-32 111.5 0.0 3.3e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGG14572.1 - 1.7e-10 40.8 0.0 2.2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGG14572.1 - 5.5e-08 32.5 0.1 2.7e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 EGG14572.1 - 0.0063 16.6 0.0 0.0089 16.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.6 EGG14572.1 - 0.088 13.1 0.0 0.18 12.1 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like SCO1-SenC PF02630.14 EGG14572.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 SCO1/SenC BB_PF PF18063.1 EGG14573.1 - 3.3e-47 160.8 7.7 6.7e-47 159.7 7.7 1.5 1 1 0 1 1 1 1 Beta barrel Pore-forming domain Shugoshin_N PF07558.11 EGG14573.1 - 0.079 12.8 0.0 0.9 9.5 0.0 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region PPR_2 PF13041.6 EGG14574.1 - 0.012 15.8 0.0 0.14 12.3 0.0 2.9 2 1 0 2 2 2 0 PPR repeat family Hemocyanin_N PF03722.14 EGG14574.1 - 0.35 11.4 0.1 0.35 11.4 0.1 3.2 4 1 0 4 4 4 0 Hemocyanin, all-alpha domain P21-Arc PF04062.14 EGG14575.1 - 6.9e-66 221.6 0.0 7.6e-66 221.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DUF3727 PF12527.8 EGG14576.1 - 0.21 11.9 3.1 0.21 11.8 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3727) N2227 PF07942.12 EGG14578.1 - 3.8e-58 196.8 8.3 8.6e-50 169.4 3.8 2.7 3 0 0 3 3 3 2 N2227-like protein Methyltransf_31 PF13847.6 EGG14578.1 - 4.9e-05 23.2 0.4 0.071 12.9 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGG14578.1 - 0.0017 18.9 0.6 0.019 15.6 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG14578.1 - 0.0026 17.6 0.0 0.013 15.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG14578.1 - 0.0047 17.6 0.0 0.0047 17.6 0.0 4.3 5 0 0 5 5 5 1 Methyltransferase domain DUF2752 PF10825.8 EGG14578.1 - 0.044 13.8 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Methyltransf_25 PF13649.6 EGG14578.1 - 0.11 13.2 0.0 4.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain SPRY PF00622.28 EGG14578.1 - 0.26 11.4 2.2 0.2 11.8 0.2 2.0 2 0 0 2 2 2 0 SPRY domain Uma2 PF05685.12 EGG14580.1 - 0.00095 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease Carm_PH PF17888.1 EGG14581.1 - 0.00066 20.0 0.2 0.0016 18.7 0.2 1.6 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_6 PF13516.6 EGG14581.1 - 0.0027 17.6 5.6 3.2 8.1 0.1 4.0 4 0 0 4 4 4 3 Leucine Rich repeat Myosin_TH1 PF06017.13 EGG14581.1 - 0.012 15.3 0.1 0.023 14.4 0.1 1.4 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding PEN-2 PF10251.9 EGG14582.1 - 2.5e-27 95.1 7.7 2.9e-27 94.9 7.7 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase Med18 PF09637.10 EGG14583.1 - 0.0021 17.9 12.6 0.0071 16.2 12.5 1.8 2 1 0 2 2 2 1 Med18 protein TFIIA PF03153.13 EGG14583.1 - 0.024 14.6 25.1 0.027 14.5 25.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM144 PF07857.12 EGG14583.1 - 0.17 10.8 0.4 0.26 10.2 0.4 1.2 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters Flavodoxin_3 PF12641.7 EGG14583.1 - 0.26 11.0 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain Med15 PF09606.10 EGG14583.1 - 0.3 9.7 28.1 0.34 9.5 28.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.9 EGG14583.1 - 0.48 8.6 16.6 0.5 8.6 16.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 EGG14583.1 - 3.2 8.4 18.4 5 7.8 18.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 EGG14583.1 - 6.9 5.3 10.6 8.7 5.0 10.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4199 PF13858.6 EGG14583.1 - 7.5 6.9 5.5 16 5.9 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) FragX_IP PF05994.11 EGG14585.1 - 0 1041.0 9.7 0 1041.0 9.7 2.5 3 1 1 4 4 4 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 EGG14585.1 - 4.9e-16 58.9 6.2 1.1e-15 57.7 6.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) LRR_4 PF12799.7 EGG14585.1 - 0.0035 17.7 3.7 0.0035 17.7 3.7 7.0 7 1 0 7 7 7 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGG14585.1 - 0.04 14.0 41.1 0.3 11.2 0.4 7.8 8 0 0 8 8 8 0 Leucine Rich repeat PGA2 PF07543.12 EGG14585.1 - 2.4 8.1 7.8 0.17 11.9 1.5 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 Cyt-b5 PF00173.28 EGG14588.1 - 2.8e-25 88.2 0.1 3.2e-25 88.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 EGG14595.1 - 4.2e-45 154.2 0.5 7.1e-31 107.5 0.3 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG14595.1 - 1.1e-25 90.5 0.1 2.9e-10 39.9 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase FUR PF01475.19 EGG14595.1 - 0.092 12.9 0.1 0.28 11.4 0.1 1.8 1 0 0 1 1 1 0 Ferric uptake regulator family EGF_2 PF07974.13 EGG14596.1 - 0.0026 18.1 20.0 0.0029 17.9 10.4 2.9 2 0 0 2 2 2 1 EGF-like domain LRR_8 PF13855.6 EGG14596.1 - 0.019 14.7 6.3 4.7 7.0 0.0 3.8 3 0 0 3 3 3 0 Leucine rich repeat Insulin_TMD PF17870.1 EGG14596.1 - 0.046 13.8 0.2 0.17 12.0 0.2 2.0 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF2712 PF10916.8 EGG14596.1 - 0.078 13.7 0.2 0.4 11.4 0.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2712) S_locus_glycop PF00954.20 EGG14596.1 - 6 7.4 10.4 0.26 11.8 1.6 3.1 2 0 0 2 2 2 0 S-locus glycoprotein domain LRR_9 PF14580.6 EGG14598.1 - 5.8e-13 48.7 5.5 1.3e-12 47.6 5.5 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGG14598.1 - 5.1e-10 39.4 21.3 2.9e-05 24.3 5.8 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG14598.1 - 2.1e-08 33.8 12.9 2.3e-06 27.3 0.5 3.8 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 EGG14598.1 - 0.052 13.6 0.1 0.052 13.6 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeat MazG_C PF18722.1 EGG14598.1 - 0.087 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 MazG C-terminal domain Guanylate_cyc PF00211.20 EGG14599.1 - 3.1e-28 98.6 0.6 6.8e-28 97.5 0.6 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Response_reg PF00072.24 EGG14599.1 - 1.9e-17 63.5 0.2 2e-08 34.4 0.1 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 EGG14599.1 - 1.4e-16 61.0 0.0 4.3e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_2 PF07719.17 EGG14599.1 - 0.03 14.4 0.1 0.076 13.2 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Sigma_reg_N PF13800.6 EGG14599.1 - 0.12 12.7 1.1 0.76 10.1 0.5 2.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Macoilin PF09726.9 EGG14599.1 - 0.13 10.8 13.5 0.21 10.1 13.5 1.2 1 0 0 1 1 1 0 Macoilin family CobD_Cbib PF03186.13 EGG14599.1 - 0.23 10.6 2.1 0.52 9.5 0.5 2.0 1 1 1 2 2 2 0 CobD/Cbib protein GREB1 PF15782.5 EGG14599.1 - 0.36 7.9 13.1 0.53 7.3 13.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 EGG14599.1 - 0.39 9.4 7.8 0.78 8.4 7.8 1.4 1 0 0 1 1 1 0 Presenilin DUF2967 PF11179.8 EGG14599.1 - 8.8 4.3 22.8 0.0044 15.2 9.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) Proteasome PF00227.26 EGG14600.1 - 1.6e-47 161.5 0.1 2.6e-47 160.8 0.1 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 EGG14600.1 - 8.4e-08 31.8 0.4 3.5e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nuf2 PF03800.14 EGG14600.1 - 0.21 11.7 0.0 0.26 11.4 0.0 1.1 1 0 0 1 1 1 0 Nuf2 family Proteasome PF00227.26 EGG14601.1 - 2.3e-06 27.2 0.1 3.3e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Sigma70_r2 PF04542.14 EGG14601.1 - 0.16 11.7 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-70 region 2 ALG3 PF05208.13 EGG14602.1 - 7.6e-142 473.0 27.8 9.6e-142 472.6 27.8 1.1 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.6 EGG14602.1 - 0.081 12.2 40.5 0.43 9.8 40.4 2.1 1 1 0 1 1 1 0 EpsG family DUF3959 PF13105.6 EGG14602.1 - 3.1 7.2 12.2 6.8 6.1 12.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) FERM_M PF00373.18 EGG14603.1 - 4.6e-20 72.2 1.4 4.6e-20 72.2 1.4 1.7 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 EGG14603.1 - 0.0072 16.3 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain HSF_DNA-bind PF00447.17 EGG14603.1 - 3.3 8.4 6.7 2.7 8.6 0.4 3.0 2 1 1 3 3 3 0 HSF-type DNA-binding Coatomer_WDAD PF04053.14 EGG14604.1 - 3.3e-156 520.8 1.0 1.5e-155 518.6 0.1 2.0 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EGG14604.1 - 1e-46 155.9 5.4 1.2e-09 38.6 0.1 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG14604.1 - 5.7e-08 33.0 0.5 0.56 10.5 0.0 6.1 4 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGG14604.1 - 0.019 15.0 0.2 22 5.2 0.0 4.7 4 2 2 6 6 6 0 Ciliary BBSome complex subunit 2, middle region RNase_PH PF01138.21 EGG14605.1 - 4.4e-17 62.8 1.8 6.5e-17 62.3 0.0 2.2 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGG14605.1 - 2.8e-11 43.3 0.0 1e-10 41.4 0.0 2.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SWI-SNF_Ssr4 PF08549.10 EGG14605.1 - 2.1 6.9 19.2 2.9 6.4 19.2 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PP-binding PF00550.25 EGG14606.1 - 5.6e-12 45.8 0.0 7.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EGG14606.1 - 0.0022 18.2 0.3 0.004 17.4 0.3 1.4 1 1 0 1 1 1 1 Acyl-carrier Rep_fac_C PF08542.11 EGG14607.1 - 8.4e-23 80.6 0.0 3.7e-22 78.5 0.0 2.1 3 0 0 3 3 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EGG14607.1 - 3.4e-14 52.9 0.3 2.9e-10 40.2 0.3 3.1 2 1 1 3 3 3 2 DNA polymerase III, delta subunit AAA PF00004.29 EGG14607.1 - 1.5e-12 48.1 0.0 2.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGG14607.1 - 2.2e-07 30.9 0.0 3.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG14607.1 - 5.8e-07 30.1 0.0 0.0002 21.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGG14607.1 - 1.7e-06 28.4 0.5 0.034 14.4 0.2 2.5 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 EGG14607.1 - 5.4e-06 26.5 0.0 1.5e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 EGG14607.1 - 2.9e-05 23.5 0.0 0.00048 19.6 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 EGG14607.1 - 6.4e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EGG14607.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG14607.1 - 0.00026 20.8 0.3 0.00076 19.2 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EGG14607.1 - 0.00056 20.2 0.0 0.002 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_19 PF13245.6 EGG14607.1 - 0.00082 19.7 0.6 0.0077 16.6 0.6 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGG14607.1 - 0.0014 18.6 0.0 0.003 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EGG14607.1 - 0.002 18.4 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG14607.1 - 0.0023 18.5 0.0 0.0061 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGG14607.1 - 0.0036 17.0 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EGG14607.1 - 0.0045 16.9 0.9 0.1 12.5 0.1 2.3 1 1 1 2 2 2 1 NTPase AAA_7 PF12775.7 EGG14607.1 - 0.0058 16.2 0.0 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGG14607.1 - 0.0061 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein DEAD PF00270.29 EGG14607.1 - 0.007 16.2 0.5 2.8 7.7 0.0 3.1 1 1 2 3 3 3 1 DEAD/DEAH box helicase RuvB_N PF05496.12 EGG14607.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 EGG14607.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EGG14607.1 - 0.014 15.8 0.1 0.092 13.1 0.0 2.3 3 0 0 3 3 3 0 RNA helicase MCM PF00493.23 EGG14607.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_3 PF07726.11 EGG14607.1 - 0.019 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EGG14607.1 - 0.025 15.1 0.2 0.048 14.1 0.2 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EGG14607.1 - 0.026 14.5 0.0 6.3 6.8 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 EGG14607.1 - 0.028 14.2 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 EGG14607.1 - 0.03 14.2 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DNA_pol3_delta PF06144.13 EGG14607.1 - 0.032 14.0 0.1 0.05 13.4 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit TniB PF05621.11 EGG14607.1 - 0.035 13.5 0.3 4 6.8 0.0 2.5 3 0 0 3 3 2 0 Bacterial TniB protein DUF2075 PF09848.9 EGG14607.1 - 0.049 12.9 0.5 0.62 9.2 0.5 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 EGG14607.1 - 0.051 13.1 0.2 0.2 11.2 0.1 1.8 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 EGG14607.1 - 0.15 12.5 0.0 0.42 11.1 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Pyrophosphatase PF00719.19 EGG14608.1 - 1.1e-46 158.6 1.0 1.5e-46 158.1 1.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Glyco_transf_8C PF08437.10 EGG14608.1 - 0.098 12.8 0.1 0.3 11.2 0.1 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal PBP1_TM PF14812.6 EGG14609.1 - 0.029 14.7 3.2 0.029 14.7 3.2 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PI3K_1B_p101 PF10486.9 EGG14609.1 - 0.093 10.5 4.9 0.1 10.4 4.9 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit IF-2B PF01008.17 EGG14610.1 - 1.6e-71 240.8 0.0 1.9e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family CN_hydrolase PF00795.22 EGG14611.1 - 2e-59 201.1 0.0 2.9e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3215 PF11503.8 EGG14611.1 - 0.038 13.8 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) DUF4446 PF14584.6 EGG14611.1 - 0.11 12.5 2.8 0.23 11.4 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) BCIP PF13862.6 EGG14612.1 - 2.7e-46 157.9 7.9 2.7e-46 157.9 7.9 2.4 2 0 0 2 2 2 1 p21-C-terminal region-binding protein Dicty_REP PF05086.12 EGG14612.1 - 0.0025 15.9 20.5 0.0025 15.9 20.5 2.2 2 0 0 2 2 2 2 Dictyostelium (Slime Mold) REP protein TRM13 PF05206.14 EGG14612.1 - 0.0064 16.1 3.3 0.0064 16.1 3.3 3.1 2 1 0 2 2 2 1 Methyltransferase TRM13 CDC27 PF09507.10 EGG14612.1 - 0.38 10.1 44.6 0.16 11.4 28.5 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 CNDH2_C PF16858.5 EGG14612.1 - 0.68 9.7 31.7 1.7 8.4 3.4 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term TFIIA PF03153.13 EGG14612.1 - 8.8 6.2 39.7 4.2 7.2 1.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Fz PF01392.22 EGG14614.1 - 5.1e-07 30.3 5.5 1.1e-06 29.2 5.5 1.6 1 0 0 1 1 1 1 Fz domain 7tm_2 PF00002.24 EGG14614.1 - 0.0024 17.2 15.7 0.0048 16.2 15.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF2784 PF10861.8 EGG14614.1 - 0.053 13.6 0.2 0.053 13.6 0.2 1.9 2 0 0 2 2 2 0 Protein of Unknown function (DUF2784) Pro_isomerase PF00160.21 EGG14615.1 - 6e-49 166.3 0.1 7e-49 166.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MWFE PF15879.5 EGG14616.1 - 1.2e-10 41.4 0.1 1.7e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit SDA1 PF05285.12 EGG14617.1 - 0.0019 17.7 15.6 0.0022 17.5 15.6 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 EGG14617.1 - 0.0028 16.0 8.7 0.0038 15.6 8.7 1.2 1 0 0 1 1 1 1 CDC45-like protein SpoIIIAH PF12685.7 EGG14617.1 - 0.012 15.5 22.5 0.16 11.8 15.3 2.1 1 1 1 2 2 2 0 SpoIIIAH-like protein SPX PF03105.19 EGG14617.1 - 0.013 15.4 29.7 0.018 15.0 29.7 1.3 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 EGG14617.1 - 0.014 14.2 11.3 0.016 13.9 11.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Utp14 PF04615.13 EGG14617.1 - 0.044 12.4 14.3 0.047 12.3 14.3 1.0 1 0 0 1 1 1 0 Utp14 protein DUF2269 PF10027.9 EGG14617.1 - 0.092 12.8 0.0 0.27 11.3 0.0 1.6 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) PulG PF11773.8 EGG14617.1 - 0.099 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin RIC3 PF15361.6 EGG14617.1 - 0.34 11.3 3.4 1.3 9.4 3.4 2.0 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 SOBP PF15279.6 EGG14617.1 - 0.74 10.4 15.6 0.88 10.1 15.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein ORC6 PF05460.13 EGG14617.1 - 0.77 9.0 17.4 0.98 8.6 17.4 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SOG2 PF10428.9 EGG14617.1 - 2.6 7.1 28.7 3.3 6.8 28.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Raftlin PF15250.6 EGG14617.1 - 3.5 6.3 13.0 4.4 5.9 13.0 1.1 1 0 0 1 1 1 0 Raftlin DUF572 PF04502.13 EGG14617.1 - 3.9 7.0 14.7 5.3 6.6 14.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2370 PF10176.9 EGG14617.1 - 5.6 6.5 8.5 44 3.6 8.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4551 PF15087.6 EGG14617.1 - 6.2 5.5 16.2 6.7 5.4 16.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Actin PF00022.19 EGG14618.1 - 1.4e-49 168.8 1.7 1.5e-27 96.2 0.0 2.3 2 0 0 2 2 2 2 Actin Ras PF00071.22 EGG14619.1 - 9.6e-08 31.8 0.5 8.5e-07 28.7 0.1 2.4 2 1 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 EGG14619.1 - 0.001 19.1 0.0 0.0028 17.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGG14619.1 - 0.007 16.8 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain PRKCSH_1 PF13015.6 EGG14619.1 - 0.012 15.3 0.1 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Roc PF08477.13 EGG14619.1 - 0.016 15.4 1.2 0.057 13.6 0.0 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 EGG14619.1 - 0.016 14.4 0.0 0.046 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EGG14619.1 - 0.024 14.6 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EGG14619.1 - 0.032 14.8 1.5 0.55 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF817 PF05675.12 EGG14619.1 - 0.058 13.1 1.4 0.086 12.5 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF817) ThiF PF00899.21 EGG14619.1 - 0.093 12.1 0.0 0.093 12.1 0.0 1.6 2 0 0 2 2 2 0 ThiF family RNA_helicase PF00910.22 EGG14619.1 - 0.099 13.0 1.3 0.81 10.1 0.0 2.8 2 1 0 2 2 2 0 RNA helicase DUF4630 PF15443.6 EGG14621.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) MIG-14_Wnt-bd PF06664.12 EGG14622.1 - 8.8e-60 202.4 27.6 8.8e-60 202.4 27.6 1.6 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Ly49 PF08391.10 EGG14624.1 - 0.11 12.9 1.4 0.16 12.3 1.4 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Ndc80_HEC PF03801.13 EGG14625.1 - 0.16 11.6 0.1 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family HI0933_like PF03486.14 EGG14626.1 - 1e-63 215.5 0.0 1.2e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EGG14626.1 - 1.1e-08 35.1 0.0 1.7e-05 24.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG14626.1 - 1.5e-05 24.4 0.2 8.6e-05 21.9 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG14626.1 - 2.5e-05 24.4 0.0 5.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGG14626.1 - 4.9e-05 22.6 0.0 8.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGG14626.1 - 0.00011 21.5 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EGG14626.1 - 0.0005 20.6 0.1 0.18 12.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGG14626.1 - 0.004 16.5 0.1 0.007 15.7 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EGG14626.1 - 0.0063 15.8 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGG14626.1 - 0.17 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 EGG14626.1 - 0.24 10.4 0.0 0.38 9.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein VanY PF02557.17 EGG14627.1 - 0.006 16.4 1.1 0.006 16.4 1.1 1.8 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Ferlin_C PF16165.5 EGG14627.1 - 1.8 8.5 8.7 3.9 7.4 8.7 1.5 1 0 0 1 1 1 0 Ferlin C-terminus DUF4710 PF15828.5 EGG14627.1 - 8.2 6.6 14.4 0.76 9.9 9.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) TrmO PF01980.16 EGG14628.1 - 6.2e-43 145.8 0.0 1.2e-42 144.8 0.0 1.5 1 0 0 1 1 1 1 tRNA-methyltransferase O SPT16 PF08644.11 EGG14628.1 - 3.9 7.6 7.4 1.1 9.5 0.7 2.4 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) UbiA PF01040.18 EGG14629.1 - 4e-44 150.8 12.2 6.5e-44 150.1 12.2 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4112 PF13430.6 EGG14629.1 - 0.0031 17.7 0.4 2.3 8.5 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4112) Glycolytic PF00274.19 EGG14629.1 - 0.0079 15.0 0.0 0.0079 15.0 0.0 1.6 2 0 0 2 2 2 1 Fructose-bisphosphate aldolase class-I DUF4181 PF13789.6 EGG14629.1 - 0.53 10.6 3.6 3.4 8.0 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Cortex-I_coil PF09304.10 EGG14630.1 - 1.3e-38 131.5 20.1 1.3e-38 131.5 20.1 2.9 3 1 0 3 3 3 1 Cortexillin I, coiled coil CH PF00307.31 EGG14630.1 - 3e-38 130.4 0.4 1e-17 64.3 0.0 2.8 3 0 0 3 3 3 2 Calponin homology (CH) domain Taxilin PF09728.9 EGG14630.1 - 0.0029 16.8 18.9 0.0072 15.5 19.0 1.5 1 1 0 1 1 1 1 Myosin-like coiled-coil protein Macoilin PF09726.9 EGG14630.1 - 0.003 16.2 10.1 0.0035 16.0 10.1 1.1 1 0 0 1 1 1 1 Macoilin family TolA_bind_tri PF16331.5 EGG14630.1 - 0.0032 17.5 7.6 0.0032 17.5 7.6 2.6 1 1 1 2 2 2 1 TolA binding protein trimerisation Baculo_PEP_C PF04513.12 EGG14630.1 - 0.34 10.9 5.2 0.35 10.9 2.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_11 PF13086.6 EGG14630.1 - 0.37 10.5 7.4 0.7 9.6 7.4 1.5 1 0 0 1 1 1 0 AAA domain T6PP_N PF18572.1 EGG14630.1 - 4.1 7.3 12.7 49 3.9 11.6 2.9 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain CENP-F_leu_zip PF10473.9 EGG14630.1 - 4.3 7.4 30.2 1.1 9.2 9.3 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EGG14630.1 - 5.3 7.1 7.7 2.1 8.4 3.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) I_LWEQ PF01608.17 EGG14632.1 - 3.9e-47 160.3 7.7 3.9e-47 160.3 7.7 4.8 4 1 1 5 5 5 2 I/LWEQ domain ANTH PF07651.16 EGG14632.1 - 8.2e-45 152.9 0.1 8.2e-45 152.9 0.1 2.1 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 EGG14632.1 - 6.1e-08 32.8 0.0 2.8e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 ENTH domain FAM184 PF15665.5 EGG14632.1 - 0.0067 16.2 7.9 0.0067 16.2 7.9 3.0 3 0 0 3 3 3 1 Family with sequence similarity 184, A and B DUF155 PF02582.14 EGG14632.1 - 0.13 12.3 2.3 0.32 11.1 2.3 1.7 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Pox_A_type_inc PF04508.12 EGG14632.1 - 0.16 11.8 1.6 0.46 10.4 0.3 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat RPW8 PF05659.11 EGG14632.1 - 2.8 7.6 8.7 53 3.5 4.4 3.6 1 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4156 PF13698.6 EGG14632.1 - 4.6 7.7 5.8 0.7 10.3 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4156) Fib_alpha PF08702.10 EGG14632.1 - 7.8 6.7 9.4 34 4.6 9.4 2.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Ank_4 PF13637.6 EGG14633.1 - 1.5e-05 25.5 0.2 2.1 9.0 0.0 4.5 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG14633.1 - 0.00026 21.5 0.0 0.81 10.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG14633.1 - 0.0016 18.7 0.2 79 4.3 0.0 5.8 6 0 0 6 6 6 0 Ankyrin repeat Ank_5 PF13857.6 EGG14633.1 - 0.0022 18.3 0.0 0.74 10.2 0.0 4.1 4 1 1 5 5 5 1 Ankyrin repeats (many copies) V-SNARE_C PF12352.8 EGG14634.1 - 0.024 14.9 1.8 0.35 11.2 0.1 2.5 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus MbeD_MobD PF04899.12 EGG14634.1 - 0.025 14.7 0.4 0.06 13.5 0.4 1.6 1 0 0 1 1 1 0 MbeD/MobD like KdpC PF02669.15 EGG14634.1 - 0.046 13.6 1.2 0.069 13.0 0.0 1.8 2 0 0 2 2 2 0 K+-transporting ATPase, c chain DASH_Hsk3 PF08227.11 EGG14634.1 - 0.19 12.1 0.4 0.37 11.2 0.4 1.4 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like GvpK PF05121.12 EGG14634.1 - 0.4 10.7 5.5 18 5.5 0.4 3.4 2 1 1 3 3 3 0 Gas vesicle protein K Ribosomal_60s PF00428.19 EGG14634.1 - 5 7.8 13.4 0.21 12.2 5.4 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Ribul_P_3_epim PF00834.19 EGG14635.1 - 4.4e-61 205.7 0.5 3e-52 176.9 0.1 2.1 1 1 1 2 2 2 2 Ribulose-phosphate 3 epimerase family Y_phosphatase2 PF03162.13 EGG14636.1 - 9.7e-26 90.3 0.4 4.3e-25 88.2 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGG14636.1 - 0.0047 16.9 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Androgen_recep PF02166.16 EGG14636.1 - 0.78 8.5 16.4 1.4 7.7 16.4 1.4 1 0 0 1 1 1 0 Androgen receptor Thioredoxin_11 PF18078.1 EGG14636.1 - 3.2 7.9 8.7 0.76 9.9 5.3 1.7 2 0 0 2 2 2 0 Thioredoxin-like SNTX domain TFIIA PF03153.13 EGG14636.1 - 8.9 6.2 35.9 0.96 9.4 30.4 1.6 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit C2 PF00168.30 EGG14637.1 - 3e-18 66.0 0.1 5.1e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 C2 domain Ank_2 PF12796.7 EGG14638.1 - 4.7e-06 27.1 1.7 0.14 12.8 0.4 5.2 3 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14638.1 - 7.7e-06 26.4 4.8 0.46 11.1 0.0 7.0 7 2 1 8 8 8 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14638.1 - 0.0013 19.0 4.1 99 4.0 0.1 7.8 9 0 0 9 9 9 0 Ankyrin repeat C2 PF00168.30 EGG14639.1 - 1.6e-24 86.1 0.1 2.5e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 EGG14639.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.4 2 0 0 2 2 2 0 CEP76 C2 domain FNIP PF05725.12 EGG14640.1 - 6.3e-13 48.7 23.9 0.019 15.1 1.5 8.5 6 2 3 9 9 9 6 FNIP Repeat LRR_1 PF00560.33 EGG14640.1 - 0.19 12.4 1.4 37 5.4 0.1 4.3 2 1 1 3 3 3 0 Leucine Rich Repeat HSP70 PF00012.20 EGG14641.1 - 1.5e-135 452.8 2.4 1.8e-135 452.5 2.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGG14641.1 - 1.2e-12 47.3 0.9 2.8e-12 46.1 0.6 1.7 1 1 1 2 2 2 1 MreB/Mbl protein PX PF00787.24 EGG14642.1 - 9.9e-17 61.0 1.1 2e-16 60.0 1.1 1.5 1 0 0 1 1 1 1 PX domain CBM_5_12_2 PF14600.6 EGG14642.1 - 0.008 16.1 0.6 0.016 15.1 0.6 1.5 1 0 0 1 1 1 1 Cellulose-binding domain Bacteroid_pep PF14406.6 EGG14642.1 - 0.026 14.9 3.7 0.087 13.2 3.7 1.9 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes NT-C2 PF10358.9 EGG14642.1 - 0.053 13.2 0.2 0.053 13.2 0.2 2.3 2 1 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins HEAT PF02985.22 EGG14643.1 - 7.3e-17 60.0 6.8 0.076 13.3 0.0 11.4 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.6 EGG14643.1 - 1.9e-11 44.2 4.3 0.0016 18.9 0.2 7.0 5 1 1 7 7 6 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGG14643.1 - 8.2e-10 39.2 5.2 0.031 14.9 0.0 7.6 5 3 4 9 9 8 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EGG14643.1 - 1.5e-08 34.9 0.1 0.032 14.6 0.0 6.5 4 2 4 8 8 8 2 HEAT repeats IBN_N PF03810.19 EGG14643.1 - 1.4e-07 31.3 0.2 1.4e-07 31.3 0.2 3.6 5 0 0 5 5 2 1 Importin-beta N-terminal domain CLASP_N PF12348.8 EGG14643.1 - 1.1e-06 28.3 6.1 0.17 11.4 0.1 6.6 6 2 2 8 8 8 1 CLASP N terminal Adaptin_N PF01602.20 EGG14643.1 - 2.2e-06 26.5 5.2 0.0025 16.5 0.1 3.4 1 1 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 EGG14643.1 - 0.00013 22.0 1.4 0.041 13.9 0.0 4.4 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 EGG14643.1 - 0.00041 19.6 6.8 0.37 9.8 0.2 5.0 3 2 1 4 4 4 1 Interferon-related developmental regulator (IFRD) MMS19_N PF14500.6 EGG14643.1 - 0.0016 18.1 0.2 0.88 9.1 0.0 3.5 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II UME PF08064.13 EGG14643.1 - 0.0038 17.1 0.5 3.3 7.7 0.0 4.8 3 2 3 6 6 6 1 UME (NUC010) domain Arm PF00514.23 EGG14643.1 - 0.0041 17.1 3.4 4.3 7.5 0.0 4.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 EGG14643.1 - 0.0043 16.3 1.7 0.35 10.0 0.1 3.5 2 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Sec7_N PF12783.7 EGG14643.1 - 0.02 14.8 3.9 0.7 9.8 1.2 4.3 5 2 1 6 6 6 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Anticodon_1 PF08264.13 EGG14643.1 - 0.028 14.4 0.7 15 5.5 0.1 3.6 2 2 2 4 4 4 0 Anticodon-binding domain of tRNA DUF577 PF04510.12 EGG14643.1 - 0.049 13.5 1.4 1.7 8.5 0.0 3.8 3 1 0 4 4 4 0 Family of unknown function (DUF577) TIP120 PF08623.10 EGG14643.1 - 0.091 12.5 1.2 3 7.6 0.3 3.4 3 1 2 5 5 5 0 TATA-binding protein interacting (TIP20) T7SS_ESX_EspC PF10824.8 EGG14643.1 - 0.12 12.9 0.5 0.86 10.1 0.0 2.6 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Dopey_N PF04118.14 EGG14643.1 - 0.28 10.3 3.2 0.68 9.0 0.1 2.7 2 1 1 3 3 3 0 Dopey, N-terminal DUF3730 PF12530.8 EGG14643.1 - 0.67 9.5 3.1 21 4.6 3.1 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3730) IFT81_CH PF18383.1 EGG14643.1 - 3.2 8.0 5.6 2.7 8.3 0.9 3.1 4 1 0 4 4 3 0 Intraflagellar transport 81 calponin homology domain DIM PF08194.12 EGG14644.1 - 0.15 12.2 2.2 0.2 11.9 2.0 1.3 1 1 0 1 1 1 0 DIM protein DUF3574 PF12098.8 EGG14646.1 - 0.076 12.8 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) HSP70 PF00012.20 EGG14648.1 - 1.4e-252 839.3 11.5 1.7e-252 839.0 11.5 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGG14648.1 - 6.2e-16 58.1 0.2 4.1e-15 55.4 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EGG14648.1 - 0.00012 22.5 1.7 0.43 11.0 0.0 3.6 3 0 0 3 3 3 1 Cell division protein FtsA DDR PF08841.10 EGG14648.1 - 0.0088 15.1 0.5 0.047 12.7 0.2 2.0 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 EGG14648.1 - 0.039 13.7 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Fes1 PF08609.10 EGG14648.1 - 0.07 14.0 4.5 0.14 13.1 0.8 2.8 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 AAA_11 PF13086.6 EGG14648.1 - 0.097 12.4 3.9 8.8 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain SAM_2 PF07647.17 EGG14649.1 - 0.0043 17.1 0.0 0.0088 16.1 0.0 1.5 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) RhoGEF PF00621.20 EGG14650.1 - 1.2e-38 133.2 0.9 1.2e-38 133.2 0.9 3.2 4 1 0 4 4 4 1 RhoGEF domain Arm PF00514.23 EGG14650.1 - 1.8e-10 40.5 19.7 0.075 13.1 0.2 9.5 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat PH PF00169.29 EGG14650.1 - 2e-09 37.9 0.6 6.3e-09 36.3 0.6 1.9 1 0 0 1 1 1 1 PH domain KAP PF05804.12 EGG14650.1 - 0.0016 16.7 9.6 0.0016 16.7 9.6 2.8 2 1 0 2 2 2 1 Kinesin-associated protein (KAP) PH_16 PF17838.1 EGG14650.1 - 0.026 14.4 4.3 0.15 11.9 4.3 2.3 1 1 0 1 1 1 0 PH domain TAF6_C PF07571.13 EGG14650.1 - 0.038 14.3 0.7 0.43 10.9 0.1 3.1 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Creb_binding PF09030.10 EGG14650.1 - 0.21 12.3 2.8 0.31 11.8 0.6 2.3 2 0 0 2 2 2 0 Creb binding NopRA1 PF16201.5 EGG14650.1 - 2.4 7.7 9.5 3.4 7.2 0.0 3.0 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 SET PF00856.28 EGG14651.1 - 5.7e-14 52.9 0.0 3.7e-13 50.2 0.0 2.1 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 EGG14651.1 - 2.9e-05 24.8 0.0 6.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Cse1 PF08506.10 EGG14652.1 - 1.9e-112 375.7 0.5 1.9e-112 375.7 0.5 1.8 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 EGG14652.1 - 6.2e-92 308.4 4.1 1.5e-91 307.2 4.1 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 EGG14652.1 - 5.6e-11 42.2 0.1 6.8e-10 38.7 0.1 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGG14652.1 - 0.033 14.2 0.4 0.033 14.2 0.4 3.1 4 0 0 4 4 4 0 Exportin 1-like protein Condensin2nSMC PF12422.8 EGG14652.1 - 0.084 13.1 3.8 0.31 11.2 0.5 3.5 4 0 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit HEAT_2 PF13646.6 EGG14652.1 - 0.11 12.9 0.0 20 5.7 0.0 3.4 4 0 0 4 4 4 0 HEAT repeats DHR10 PF18595.1 EGG14653.1 - 0.0084 16.2 6.8 0.017 15.1 6.8 1.5 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain DUF1664 PF07889.12 EGG14653.1 - 0.021 14.9 0.9 0.038 14.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CCDC53 PF10152.9 EGG14653.1 - 0.15 12.5 5.5 0.23 11.9 5.5 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex MetOD2 PF18548.1 EGG14653.1 - 0.16 12.1 4.7 1.8 8.8 1.4 3.0 2 1 1 3 3 3 0 Metanogen output domain 2 Mucin PF01456.17 EGG14653.1 - 0.25 11.4 17.7 0.36 10.8 17.7 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein CPSF100_C PF13299.6 EGG14653.1 - 0.4 10.9 6.2 0.19 11.9 3.5 1.6 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3439 PF11921.8 EGG14653.1 - 0.4 10.7 10.9 0.63 10.0 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4808 PF16066.5 EGG14653.1 - 0.43 11.1 2.0 0.59 10.7 1.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4808) SSP160 PF06933.11 EGG14653.1 - 0.63 8.2 12.5 0.8 7.8 12.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Angiomotin_C PF12240.8 EGG14653.1 - 0.71 9.4 10.0 0.69 9.4 0.8 2.3 2 0 0 2 2 2 0 Angiomotin C terminal FPP PF05911.11 EGG14653.1 - 3 5.9 17.0 0.011 14.0 5.8 1.9 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil MGC-24 PF05283.11 EGG14653.1 - 5 7.6 12.4 8.4 6.8 12.4 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Chordopox_G3 PF06129.12 EGG14654.1 - 0.015 16.0 0.8 0.024 15.3 0.8 1.2 1 0 0 1 1 1 0 Chordopoxvirus G3 protein SR-25 PF10500.9 EGG14655.1 - 0.13 11.8 23.8 0.28 10.7 23.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 EGG14655.1 - 0.56 8.7 8.0 0.71 8.4 8.0 1.1 1 0 0 1 1 1 0 Macoilin family Secretin_N_2 PF07655.13 EGG14655.1 - 0.66 10.6 18.7 1.8 9.1 18.7 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain RAP1 PF07218.11 EGG14655.1 - 1.6 6.9 14.8 2.6 6.2 14.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4614 PF15391.6 EGG14655.1 - 2.6 8.0 13.5 4.2 7.3 13.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Tmemb_cc2 PF10267.9 EGG14655.1 - 7.3 5.6 5.4 11 5.0 5.4 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CCDC24 PF15669.5 EGG14655.1 - 7.9 6.3 7.2 12 5.7 7.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family HEAT PF02985.22 EGG14656.1 - 0.0048 17.1 0.4 1.6 9.2 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat FKS1_dom1 PF14288.6 EGG14656.1 - 5.9 7.2 8.5 22 5.4 0.2 4.4 4 0 0 4 4 4 0 1,3-beta-glucan synthase subunit FKS1, domain-1 PP2C PF00481.21 EGG14657.1 - 3.5e-59 200.6 0.0 6.8e-59 199.6 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_6 PF13516.6 EGG14657.1 - 1e-05 25.2 10.7 0.065 13.3 0.1 4.8 4 0 0 4 4 4 2 Leucine Rich repeat PP2C_2 PF13672.6 EGG14657.1 - 9.2e-05 22.2 0.1 0.00038 20.2 0.0 2.2 2 1 0 2 2 2 1 Protein phosphatase 2C LRR_8 PF13855.6 EGG14657.1 - 0.024 14.4 4.1 2.9 7.7 0.2 3.2 2 1 0 2 2 2 0 Leucine rich repeat DUF4488 PF14869.6 EGG14657.1 - 0.065 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) DUF3361 PF11841.8 EGG14658.1 - 0.0052 16.7 1.7 2.2 8.2 0.4 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) Pex14_N PF04695.13 EGG14658.1 - 0.18 12.4 8.8 0.2 12.3 2.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Menin PF05053.13 EGG14658.1 - 6.4 5.0 11.8 2.1 6.6 8.9 1.6 2 0 0 2 2 2 0 Menin ALMT PF11744.8 EGG14658.1 - 6.4 5.5 10.0 2.3 7.0 7.2 1.5 2 0 0 2 2 2 0 Aluminium activated malate transporter Ank_2 PF12796.7 EGG14659.1 - 1.4e-33 115.3 0.1 3e-14 53.4 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14659.1 - 4.6e-30 103.6 0.0 1.1e-06 29.1 0.0 5.3 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG14659.1 - 1.9e-21 75.8 0.3 2.8e-05 24.3 0.0 6.4 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14659.1 - 6.7e-20 69.1 0.0 0.0091 16.4 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 EGG14659.1 - 7.4e-17 61.0 0.0 0.036 14.5 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Endotoxin_N PF03945.14 EGG14660.1 - 4.8e-40 137.6 1.7 7.5e-40 137.0 1.7 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain TFIIE_alpha PF02002.17 EGG14661.1 - 3.2e-13 49.5 2.6 6.3e-13 48.5 2.6 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit Rrf2 PF02082.20 EGG14661.1 - 0.0021 18.4 0.0 0.0059 16.9 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator DUF3123 PF11321.8 EGG14661.1 - 0.1 13.3 1.4 0.3 11.8 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) TFIIE-A_C PF11521.8 EGG14661.1 - 4.1 7.8 8.4 0.15 12.4 0.7 2.5 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Amidinotransf PF02274.17 EGG14662.1 - 3.5e-57 194.0 0.5 3.3e-55 187.6 0.5 2.0 1 1 0 1 1 1 1 Amidinotransferase DUF908 PF06012.12 EGG14663.1 - 0.09 12.2 11.2 0.12 11.8 11.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) FAM53 PF15242.6 EGG14663.1 - 0.092 12.6 14.9 0.12 12.2 14.9 1.1 1 0 0 1 1 1 0 Family of FAM53 Macoilin PF09726.9 EGG14663.1 - 0.27 9.8 10.7 0.29 9.6 10.7 1.1 1 0 0 1 1 1 0 Macoilin family PPR_3 PF13812.6 EGG14664.1 - 0.0029 17.6 0.1 0.029 14.4 0.0 2.6 3 1 1 4 4 4 1 Pentatricopeptide repeat domain ATP13 PF12921.7 EGG14664.1 - 0.029 14.2 0.5 3.2 7.6 0.0 3.6 3 1 1 4 4 4 0 Mitochondrial ATPase expression TFA2_Winged_2 PF18121.1 EGG14665.1 - 2.5e-11 43.1 0.3 5.2e-11 42.1 0.3 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 UCH PF00443.29 EGG14667.1 - 4.9e-41 140.9 48.1 3.4e-23 82.5 6.0 4.2 2 2 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGG14667.1 - 1.7e-10 41.1 10.0 1.7e-10 41.1 10.0 2.9 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGG14667.1 - 7.1e-05 22.5 36.8 7.1e-05 22.5 36.8 5.9 2 2 2 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EGG14667.1 - 0.00015 21.5 0.7 0.00042 20.0 0.7 1.8 1 0 0 1 1 1 1 Variant UBP zinc finger DUF4746 PF15928.5 EGG14667.1 - 0.003 17.0 4.1 0.003 17.0 4.1 5.6 4 2 1 5 5 5 1 Domain of unknown function (DUF4746) DUF3439 PF11921.8 EGG14667.1 - 0.0042 17.0 4.4 0.0042 17.0 4.4 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3439) Pex14_N PF04695.13 EGG14668.1 - 1.9e-30 106.6 10.3 1.9e-30 106.6 10.3 8.2 3 2 2 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5572 PF17733.1 EGG14668.1 - 3e-06 27.0 1.9 3e-06 27.0 1.9 2.9 2 0 0 2 2 2 1 Family of unknown function (DUF5572) Serglycin PF04360.12 EGG14668.1 - 0.0043 17.0 1.5 0.0043 17.0 1.5 3.7 3 1 1 4 4 4 1 Serglycin Spt5_N PF11942.8 EGG14668.1 - 0.0083 17.1 1.7 0.0083 17.1 1.7 4.8 5 1 0 5 5 5 1 Spt5 transcription elongation factor, acidic N-terminal MRP-S27 PF10037.9 EGG14668.1 - 0.0096 14.8 1.5 0.0096 14.8 1.5 3.6 4 1 0 4 4 4 1 Mitochondrial 28S ribosomal protein S27 SUIM_assoc PF16619.5 EGG14668.1 - 0.043 13.9 0.0 0.043 13.9 0.0 11.2 9 3 3 12 12 12 0 Unstructured region C-term to UIM in Ataxin3 LapA_dom PF06305.11 EGG14668.1 - 0.59 10.0 0.0 0.59 10.0 0.0 3.5 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain ERG4_ERG24 PF01222.17 EGG14669.1 - 2.2e-52 178.3 4.0 2.4e-52 178.1 4.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGG14669.1 - 0.0013 18.3 0.9 0.0023 17.5 0.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) zf-HC5HC2H_2 PF13832.6 EGG14670.1 - 4.9e-23 81.4 7.3 4.9e-23 81.4 7.3 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 EGG14670.1 - 7.6e-22 78.4 22.8 7.6e-22 78.4 22.8 5.9 4 2 1 5 5 5 1 Enhancer of polycomb-like Bromodomain PF00439.25 EGG14670.1 - 5.1e-18 64.9 1.1 5.1e-18 64.9 1.1 2.1 2 0 0 2 2 2 1 Bromodomain zf-HC5HC2H PF13771.6 EGG14670.1 - 4.1e-16 59.0 4.2 4.1e-16 59.0 4.2 3.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EGG14670.1 - 2.2e-13 49.5 4.3 2.2e-13 49.5 4.3 2.8 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EGG14670.1 - 1e-10 41.3 26.9 7.7e-10 38.5 6.6 3.0 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 EGG14670.1 - 0.0042 16.7 4.0 0.0042 16.7 4.0 3.5 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain RhoGEF PF00621.20 EGG14671.1 - 1.2e-34 120.1 1.3 1.2e-34 120.1 1.3 2.4 2 0 0 2 2 2 1 RhoGEF domain DZR PF12773.7 EGG14671.1 - 0.064 13.3 1.0 0.15 12.1 1.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon THOC7 PF05615.13 EGG14672.1 - 1e-21 77.6 15.4 1e-21 77.6 15.4 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 DUF948 PF06103.11 EGG14672.1 - 0.019 15.2 2.1 0.019 15.2 2.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SLATT_fungal PF18142.1 EGG14672.1 - 0.036 14.1 7.1 1.5 8.8 0.2 3.1 3 1 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain PilJ PF13675.6 EGG14672.1 - 0.32 11.0 7.3 1.8 8.6 3.9 2.5 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.12 EGG14672.1 - 0.75 9.8 11.0 0.5 10.4 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 EGG14672.1 - 0.77 10.0 20.0 0.08 13.2 2.1 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EGG14672.1 - 1.2 8.5 7.8 1.4 8.2 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 EGG14672.1 - 2.2 8.5 21.6 0.46 10.7 17.7 1.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Yippee-Mis18 PF03226.14 EGG14673.1 - 7.9e-05 22.8 1.1 0.00012 22.3 1.1 1.3 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.9 EGG14673.1 - 0.017 15.5 1.2 0.023 15.0 1.2 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) RIO1 PF01163.22 EGG14674.1 - 2.1e-49 167.7 0.2 2.1e-49 167.7 0.2 2.3 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 EGG14674.1 - 1.2e-31 108.7 0.1 2.8e-31 107.6 0.1 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EGG14674.1 - 2.6e-09 37.4 0.0 7.4e-05 22.8 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGG14674.1 - 2.8e-08 33.4 0.1 3.5e-07 29.8 0.1 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGG14674.1 - 0.024 14.0 0.1 0.079 12.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 EGG14674.1 - 0.046 13.1 0.2 0.046 13.1 0.2 2.1 2 1 0 2 2 2 0 Protein kinase domain RabGAP-TBC PF00566.18 EGG14675.1 - 1.7e-42 145.5 0.2 1.7e-42 145.5 0.2 2.6 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DNA_primase_lrg PF04104.14 EGG14675.1 - 0.022 14.2 1.5 0.042 13.2 0.6 1.8 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit DUF1068 PF06364.12 EGG14675.1 - 0.14 12.0 3.8 0.3 10.9 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) DUF2951 PF11166.8 EGG14675.1 - 1.4 9.2 7.5 3.8 7.8 7.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) TMEM51 PF15345.6 EGG14675.1 - 1.6 8.5 7.3 2.7 7.8 7.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 FAD_binding_3 PF01494.19 EGG14676.1 - 2.6e-19 69.7 0.0 3.7e-07 29.7 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 EGG14676.1 - 0.0033 17.1 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGG14676.1 - 0.004 17.4 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGG14676.1 - 0.017 14.2 0.0 0.037 13.1 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EGG14676.1 - 0.039 13.2 0.0 0.081 12.1 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGG14676.1 - 0.054 12.7 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Thi4 family SR-25 PF10500.9 EGG14676.1 - 0.34 10.5 3.0 0.58 9.7 3.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNase_PH PF01138.21 EGG14677.1 - 2.7e-20 73.2 0.0 4.1e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGG14677.1 - 8.6e-13 48.1 0.3 1.7e-12 47.2 0.3 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 TFIID-31kDa PF02291.15 EGG14678.1 - 0.00065 19.8 0.1 0.059 13.4 0.0 2.3 2 0 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EGG14678.1 - 0.0065 16.7 0.4 0.33 11.3 0.1 2.5 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGG14678.1 - 0.064 13.6 1.1 7.6 6.9 0.1 2.4 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TRAP_beta PF05753.14 EGG14679.1 - 2.3e-46 157.4 0.2 2.9e-46 157.1 0.2 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) zf-LITAF-like PF10601.9 EGG14679.1 - 0.12 12.7 0.4 0.27 11.5 0.2 1.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Ank_2 PF12796.7 EGG14680.1 - 3.7e-05 24.2 0.2 0.33 11.6 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG14680.1 - 0.003 17.9 0.1 12 6.9 0.0 4.8 3 1 1 4 4 4 1 Ankyrin repeat RteC PF09357.10 EGG14680.1 - 0.01 15.5 0.5 0.01 15.5 0.5 2.9 3 0 0 3 3 3 0 RteC protein Ank_4 PF13637.6 EGG14680.1 - 0.013 16.1 3.7 0.63 10.7 0.0 3.9 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG14680.1 - 0.16 12.4 0.1 0.72 10.2 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) TERB2 PF15101.6 EGG14681.1 - 2.8 8.0 8.2 1.8 8.6 3.4 2.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Arf PF00025.21 EGG14682.1 - 7.3e-50 168.8 0.1 9.4e-50 168.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGG14682.1 - 5.8e-15 55.3 2.0 2.3e-12 46.8 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EGG14682.1 - 2.8e-11 43.7 0.0 4.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG14682.1 - 2.1e-09 37.2 0.0 2.9e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGG14682.1 - 4.5e-09 36.0 0.0 6.3e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGG14682.1 - 1.1e-08 34.7 0.0 1.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG14682.1 - 2.4e-06 27.6 0.0 3.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG14682.1 - 0.00019 21.4 0.1 0.27 11.1 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGG14682.1 - 0.00052 20.3 0.0 0.0011 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EGG14682.1 - 0.00087 18.9 0.6 0.026 14.1 0.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 EGG14682.1 - 0.0024 17.5 0.9 0.42 10.2 0.2 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EGG14682.1 - 0.0072 16.8 0.4 0.012 16.1 0.4 1.6 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGG14682.1 - 0.011 16.2 0.1 0.046 14.1 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EGG14682.1 - 0.011 16.2 2.4 0.024 15.2 2.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGG14682.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGG14682.1 - 0.023 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.17 EGG14682.1 - 0.025 14.3 0.1 0.05 13.3 0.1 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_18 PF13238.6 EGG14682.1 - 0.027 15.0 0.1 0.12 12.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGG14682.1 - 0.033 14.6 0.3 0.062 13.7 0.1 1.6 2 0 0 2 2 1 0 AAA domain SRP54 PF00448.22 EGG14682.1 - 0.22 11.1 0.4 0.45 10.1 0.2 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Methyltransf_31 PF13847.6 EGG14683.1 - 3.9e-13 49.5 0.0 1.3e-12 47.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmC_N PF17827.1 EGG14683.1 - 1.5e-10 41.5 0.0 1.1e-09 38.7 0.0 2.3 3 0 0 3 3 2 1 PrmC N-terminal domain MTS PF05175.14 EGG14683.1 - 2e-10 40.5 0.0 3.7e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGG14683.1 - 6.5e-07 30.0 0.0 2.1e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG14683.1 - 5.4e-05 23.1 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG14683.1 - 0.00045 20.9 0.5 0.0017 19.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGG14683.1 - 0.00075 19.2 0.1 0.0022 17.6 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PrmA PF06325.13 EGG14683.1 - 0.0021 17.5 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EGG14683.1 - 0.0037 17.2 0.1 0.044 13.7 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_15 PF09445.10 EGG14683.1 - 0.0051 16.4 1.0 0.0083 15.7 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 EGG14683.1 - 0.0064 17.1 0.0 0.017 15.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 EGG14683.1 - 0.013 15.0 0.1 0.48 9.9 0.0 2.1 2 0 0 2 2 2 0 MraW methylase family Eco57I PF07669.11 EGG14683.1 - 0.018 15.5 0.2 0.13 12.8 0.0 2.4 2 1 1 3 3 3 0 Eco57I restriction-modification methylase Methyltransf_16 PF10294.9 EGG14683.1 - 0.069 12.9 0.2 0.13 12.0 0.2 1.5 1 1 0 1 1 1 0 Lysine methyltransferase MetW PF07021.12 EGG14683.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Peptidase_M24 PF00557.24 EGG14684.1 - 8.3e-37 126.9 0.0 1.1e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 EGG14684.1 - 0.0018 18.4 2.8 0.0027 17.8 2.8 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DUF3381 PF11861.8 EGG14684.1 - 2.9 7.6 10.2 6.2 6.6 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Coilin_N PF15862.5 EGG14684.1 - 3.3 7.5 8.6 9.1 6.1 8.6 1.7 1 0 0 1 1 1 0 Coilin N-terminus WD40 PF00400.32 EGG14685.1 - 2.4e-15 56.6 21.6 5.8e-05 23.8 0.3 7.8 7 1 1 8 8 8 3 WD domain, G-beta repeat eIF2A PF08662.11 EGG14685.1 - 1.5e-07 31.5 0.0 7.1e-05 22.8 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EGG14685.1 - 6e-05 23.3 0.2 4.4 7.7 0.0 5.4 4 3 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Aldo_ket_red PF00248.21 EGG14686.1 - 4.4e-54 183.7 0.0 5e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_20 PF00728.22 EGG14686.1 - 0.00044 19.7 0.1 0.00072 19.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain SNRNP27 PF08648.12 EGG14686.1 - 0.11 12.6 0.0 8.2 6.6 0.0 2.4 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins Foie-gras_1 PF11817.8 EGG14687.1 - 1.4e-34 119.9 0.2 3.3e-34 118.7 0.2 1.7 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.12 EGG14687.1 - 1.2e-06 27.6 5.2 5.2e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi TRAPPC10 PF12584.8 EGG14687.1 - 0.0001 22.1 0.7 0.0046 16.7 0.0 3.5 4 0 0 4 4 4 1 Trafficking protein particle complex subunit 10, TRAPPC10 USP7_C2 PF14533.6 EGG14688.1 - 0.15 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Perilipin PF03036.16 EGG14689.1 - 1.9e-05 23.9 6.8 0.0044 16.1 6.4 3.3 1 1 0 1 1 1 1 Perilipin family REF PF05755.12 EGG14689.1 - 0.0011 18.9 1.1 0.0028 17.5 0.1 2.2 2 1 0 2 2 2 1 Rubber elongation factor protein (REF) DUF2661 PF10860.8 EGG14689.1 - 0.03 14.4 0.1 0.07 13.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2661) DUF3461 PF11944.8 EGG14689.1 - 0.21 11.7 5.1 0.21 11.8 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3461) Ldh_1_C PF02866.18 EGG14691.1 - 6e-33 114.1 0.0 1.1e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGG14691.1 - 1.4e-32 112.7 0.2 2.2e-32 112.1 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Rad60-SLD PF11976.8 EGG14692.1 - 5.8e-22 77.3 0.0 7.1e-22 77.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGG14692.1 - 1.1e-13 50.7 0.0 1.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 EGG14692.1 - 0.071 13.3 0.0 0.079 13.2 0.0 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain HicB PF05534.12 EGG14692.1 - 0.16 11.8 0.1 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 HicB family Ank_2 PF12796.7 EGG14693.1 - 4e-26 91.4 0.1 2.4e-10 40.9 0.2 4.7 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14693.1 - 1.6e-22 79.5 0.0 3e-05 24.5 0.1 5.4 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG14693.1 - 7e-21 74.0 1.1 1.4e-08 34.8 0.0 6.0 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EGG14693.1 - 2.7e-17 62.3 0.5 0.13 12.7 0.0 6.8 6 1 1 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 EGG14693.1 - 5.5e-17 60.1 0.0 0.63 10.8 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat PRCC PF10253.9 EGG14693.1 - 0.14 13.0 3.4 0.21 12.4 3.4 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Ank_2 PF12796.7 EGG14694.1 - 1.4e-34 118.6 6.4 1.4e-14 54.4 0.2 3.7 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14694.1 - 5.8e-30 103.3 1.1 4.4e-08 33.5 0.0 5.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG14694.1 - 2.1e-27 94.8 0.5 5e-10 39.4 0.0 7.4 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14694.1 - 2.8e-26 88.7 0.3 0.021 15.3 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 EGG14694.1 - 4.4e-24 83.8 1.4 0.0037 17.7 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat DUF3447 PF11929.8 EGG14694.1 - 0.0098 15.8 1.9 0.31 11.0 0.3 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) CTP_transf_1 PF01148.20 EGG14695.1 - 0.0014 18.4 7.4 0.002 17.9 7.4 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family RAMP4 PF06624.12 EGG14695.1 - 0.25 11.5 2.7 17 5.5 0.7 2.4 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Transgly_assoc PF04226.13 EGG14695.1 - 3.2 8.1 10.4 14 6.0 0.9 3.1 2 1 0 2 2 2 0 Transglycosylase associated protein Na_Ca_ex PF01699.24 EGG14695.1 - 3.2 7.7 17.1 1.7 8.6 12.7 2.4 2 1 0 2 2 2 0 Sodium/calcium exchanger protein Ank_2 PF12796.7 EGG14696.1 - 1.2e-29 102.7 1.8 9.2e-15 55.0 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14696.1 - 7.3e-29 99.8 0.7 1.9e-08 34.6 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG14696.1 - 5.8e-20 71.1 3.3 5.4e-08 33.0 0.1 6.3 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14696.1 - 7.4e-19 65.9 0.9 0.0052 17.2 0.0 7.2 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 EGG14696.1 - 1.2e-17 63.5 0.3 6.2e-05 23.3 0.0 7.1 6 1 0 6 6 6 3 Ankyrin repeat DUF1815 PF08844.10 EGG14696.1 - 0.041 13.8 0.0 2.6 8.1 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1815) Pkinase_Tyr PF07714.17 EGG14697.1 - 3.8e-58 196.8 10.1 8.7e-34 117.0 0.1 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 EGG14697.1 - 1.2e-50 172.4 12.0 7.8e-32 110.7 0.1 3.8 3 1 1 4 4 4 2 Protein kinase domain Kelch_3 PF13415.6 EGG14697.1 - 3.6e-23 81.3 5.2 2.8e-09 37.0 0.1 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG14697.1 - 4.2e-22 77.7 1.6 0.0004 20.3 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EGG14697.1 - 1.8e-20 72.7 5.4 9.4e-10 38.3 0.1 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EGG14697.1 - 5.1e-16 58.3 4.5 0.00012 22.2 0.0 5.9 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EGG14697.1 - 1.3e-14 53.5 0.7 0.00085 18.9 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EGG14697.1 - 6.3e-14 51.3 4.8 0.00015 21.6 0.0 5.7 6 0 0 6 6 6 2 Kelch motif BT1 PF03092.16 EGG14697.1 - 0.1 10.8 0.0 0.21 9.8 0.0 1.4 1 0 0 1 1 1 0 BT1 family CLN3 PF02487.17 EGG14697.1 - 2.5 7.0 21.2 0.57 9.2 0.5 4.2 4 0 0 4 4 4 0 CLN3 protein Glu-tRNAGln PF02686.15 EGG14699.1 - 6.3e-10 39.2 0.1 1.1e-09 38.4 0.1 1.4 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Homeodomain PF00046.29 EGG14700.1 - 6.3e-19 67.6 4.6 1.2e-18 66.7 4.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGG14700.1 - 0.0037 17.1 0.2 0.0082 16.0 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain RrnaAD PF00398.20 EGG14701.1 - 2.4e-62 210.4 0.0 3e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGG14701.1 - 1e-07 32.6 0.0 2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG14701.1 - 3.1e-05 24.6 0.0 6.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG14701.1 - 0.00014 22.6 0.0 0.00027 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGG14701.1 - 0.0002 21.2 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 EGG14701.1 - 0.00083 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 EGG14701.1 - 0.003 17.4 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGG14701.1 - 0.0033 16.8 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 EGG14701.1 - 0.013 14.7 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 EGG14701.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 EGG14701.1 - 0.02 14.8 0.0 0.065 13.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 EGG14701.1 - 0.025 13.9 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_31 PF13847.6 EGG14701.1 - 0.04 13.7 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 EGG14701.1 - 0.065 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Histone methylation protein DOT1 Ubie_methyltran PF01209.18 EGG14701.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family C2 PF00168.30 EGG14702.1 - 0.001 19.3 0.0 0.0028 17.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain C2-C2_1 PF11618.8 EGG14702.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 CCT_2 PF09425.10 EGG14702.1 - 0.15 12.0 0.5 0.32 10.9 0.5 1.5 1 0 0 1 1 1 0 Divergent CCT motif LUC7 PF03194.15 EGG14702.1 - 1.7 8.2 12.6 2 8.0 1.4 2.6 2 1 0 2 2 2 0 LUC7 N_terminus Ribosomal_60s PF00428.19 EGG14702.1 - 7 7.3 14.1 1.1 9.9 0.4 4.2 4 0 0 4 4 4 0 60s Acidic ribosomal protein DUF4709 PF15821.5 EGG14703.1 - 1.2 9.5 11.9 0.48 10.7 9.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) Cdh1_DBD_1 PF18196.1 EGG14703.1 - 1.8 8.9 8.5 0.77 10.1 0.7 3.0 1 1 2 3 3 3 0 Chromodomain helicase DNA-binding domain 1 SdrD_B PF17210.3 EGG14704.1 - 5.4e-06 26.6 0.2 5.4e-06 26.6 0.2 3.1 2 1 0 2 2 1 1 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG14704.1 - 1.3e-05 25.3 0.1 8.5e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain V_ATPase_I PF01496.19 EGG14704.1 - 0.002 16.2 0.2 0.0028 15.7 0.2 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Amnionless PF14828.6 EGG14704.1 - 0.023 13.5 2.5 0.049 12.5 2.0 1.7 2 0 0 2 2 2 0 Amnionless Filamin PF00630.19 EGG14704.1 - 0.025 15.4 2.4 0.12 13.2 2.4 2.3 1 1 0 1 1 1 0 Filamin/ABP280 repeat CYTH PF01928.21 EGG14704.1 - 0.027 14.4 0.3 0.047 13.6 0.3 1.3 1 0 0 1 1 1 0 CYTH domain EOS1 PF12326.8 EGG14704.1 - 0.51 10.2 4.0 1 9.3 4.0 1.4 1 0 0 1 1 1 0 N-glycosylation protein CSG2 PF16965.5 EGG14704.1 - 2.1 7.2 12.8 0.93 8.4 10.5 1.6 1 1 1 2 2 2 0 Ceramide synthase regulator DUF4834 PF16118.5 EGG14704.1 - 3.5 8.7 8.2 7 7.7 5.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) HCO3_cotransp PF00955.21 EGG14704.1 - 6.7 5.4 7.5 11 4.7 7.5 1.2 1 0 0 1 1 1 0 HCO3- transporter family AI-2E_transport PF01594.16 EGG14704.1 - 7.2 5.7 7.2 16 4.5 7.2 1.5 1 0 0 1 1 1 0 AI-2E family transporter PQQ_2 PF13360.6 EGG14705.1 - 0.039 13.5 0.0 0.08 12.5 0.0 1.6 1 1 0 1 1 1 0 PQQ-like domain DUF2341 PF10102.9 EGG14705.1 - 0.1 13.2 1.2 0.22 12.1 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2341) fn3 PF00041.21 EGG14706.1 - 1e-09 38.6 22.2 0.00067 20.0 0.1 9.2 11 1 0 11 11 11 4 Fibronectin type III domain PilA4 PF18682.1 EGG14706.1 - 0.022 15.1 4.3 11 6.4 0.3 4.9 3 0 0 3 3 3 0 Pilin A4 Ribosomal_S27 PF01599.19 EGG14706.1 - 0.095 12.9 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein S27a EGF PF00008.27 EGG14706.1 - 0.36 11.2 11.5 0.14 12.5 7.8 2.4 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 EGG14706.1 - 0.65 10.7 5.4 4.9 7.9 5.4 2.7 1 0 0 1 1 1 0 Human growth factor-like EGF Laminin_EGF PF00053.24 EGG14706.1 - 1.4 9.1 5.1 4.3 7.6 5.1 1.8 1 0 0 1 1 1 0 Laminin EGF domain DUF2369 PF10179.9 EGG14706.1 - 2 8.8 5.0 11 6.4 0.1 4.1 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) EGF_2 PF07974.13 EGG14706.1 - 9.1 6.8 14.9 2.7 8.4 10.3 2.4 2 0 0 2 2 2 0 EGF-like domain EXS PF03124.14 EGG14707.1 - 2.4e-70 237.5 23.2 5.5e-70 236.3 23.2 1.6 1 1 0 1 1 1 1 EXS family SPX PF03105.19 EGG14707.1 - 1.8e-28 100.6 16.8 5e-16 59.6 5.4 2.5 1 1 1 2 2 2 2 SPX domain FAM76 PF16046.5 EGG14707.1 - 2 7.7 7.8 0.068 12.5 1.8 1.5 2 0 0 2 2 2 0 FAM76 protein NAP PF00956.18 EGG14708.1 - 1e-12 47.8 22.5 8.2e-10 38.3 11.5 2.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Voldacs PF03517.13 EGG14708.1 - 0.014 15.6 7.2 0.025 14.7 7.2 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling SpvB PF03534.13 EGG14708.1 - 0.045 12.9 0.3 0.045 12.9 0.3 2.4 1 1 2 3 3 3 0 Salmonella virulence plasmid 65kDa B protein SecA_SW PF07516.13 EGG14708.1 - 0.2 11.7 7.1 0.23 11.5 7.0 1.3 1 1 0 1 1 1 0 SecA Wing and Scaffold domain Ly49 PF08391.10 EGG14708.1 - 5.5 7.4 7.0 1.1 9.7 0.6 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region CENP-B_dimeris PF09026.10 EGG14708.1 - 8.2 6.9 14.8 0.39 11.1 8.7 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BSP_II PF05432.11 EGG14708.1 - 8.3 6.0 16.5 0.13 11.9 9.8 1.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DNA_pol_B PF00136.21 EGG14709.1 - 1.4e-96 324.0 0.4 2.7e-96 323.1 0.4 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGG14709.1 - 1e-25 90.6 10.1 7.3e-17 61.5 0.0 3.3 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGG14709.1 - 4.8e-13 49.4 6.2 1.6e-12 47.7 6.2 2.0 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RAWUL PF16207.5 EGG14710.1 - 0.31 11.8 0.0 0.31 11.8 0.0 3.2 2 1 0 2 2 2 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Peptidase_C1 PF00112.23 EGG14711.1 - 9.4e-78 261.2 3.9 1.4e-77 260.7 3.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG14711.1 - 5.4e-14 52.4 4.3 5.4e-14 52.4 4.3 1.8 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGG14711.1 - 0.00094 18.1 8.6 0.047 12.5 2.5 3.2 2 2 1 3 3 3 3 Peptidase C1-like family Resolvase PF00239.21 EGG14712.1 - 7.1e-05 23.0 0.0 0.017 15.2 0.0 2.7 2 0 0 2 2 2 2 Resolvase, N terminal domain CRA PF06589.11 EGG14712.1 - 0.045 13.9 15.2 0.24 11.5 15.2 2.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) PBP1_TM PF14812.6 EGG14712.1 - 0.1 13.0 4.6 0.3 11.5 4.6 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1754 PF08555.10 EGG14712.1 - 0.14 13.0 12.8 0.43 11.4 12.8 1.8 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) RVT_1 PF00078.27 EGG14714.1 - 3.2e-31 108.6 0.4 5.5e-31 107.8 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EGG14714.1 - 2.2e-16 59.7 0.0 5.3e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 EGG14714.1 - 3.7e-11 43.3 0.0 1.1e-10 41.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 EGG14714.1 - 4e-11 43.1 0.0 1.8e-10 40.9 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein RT_RNaseH PF17917.1 EGG14714.1 - 2e-08 34.4 0.0 5.7e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 EGG14714.1 - 5.7e-06 26.2 0.1 1.2e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Nup188 PF10487.9 EGG14714.1 - 0.046 11.6 0.0 0.074 11.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 BB_PF PF18063.1 EGG14715.1 - 2.9e-49 167.5 0.2 5.3e-49 166.6 0.2 1.4 1 1 0 1 1 1 1 Beta barrel Pore-forming domain Myosin_TH1 PF06017.13 EGG14716.1 - 4.1e-28 98.3 1.9 6.5e-28 97.7 1.9 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding CPBP PF02517.16 EGG14716.1 - 2.2e-09 37.5 1.0 2.2e-09 37.5 1.0 1.9 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease Glyco_hydro_18 PF00704.28 EGG14717.1 - 1.5e-06 28.2 0.2 2.3e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Metallophos_C PF14008.6 EGG14718.1 - 2.5e-23 82.7 0.5 1.3e-22 80.4 0.0 2.5 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EGG14718.1 - 7.4e-19 68.1 3.4 2.7e-18 66.3 3.4 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 EGG14718.1 - 5.1e-13 50.0 0.7 9.3e-13 49.1 0.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ThrE PF06738.12 EGG14719.1 - 1.3e-63 214.6 20.2 3.3e-55 187.1 5.3 2.5 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EGG14719.1 - 9.9e-07 29.0 7.3 9.9e-07 29.0 7.3 2.6 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE TruB_C_2 PF16198.5 EGG14719.1 - 0.019 15.1 0.0 0.05 13.8 0.0 1.7 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain TFIIA PF03153.13 EGG14719.1 - 1.6 8.6 25.7 2.6 8.0 25.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 EGG14721.1 - 0.00097 19.2 25.6 0.00097 19.2 25.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 EGG14721.1 - 0.053 13.1 16.9 0.061 12.9 16.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GAS PF13851.6 EGG14721.1 - 0.072 12.4 29.5 0.11 11.8 29.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 EGG14721.1 - 0.088 11.4 10.8 0.1 11.2 10.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fumble PF03630.14 EGG14721.1 - 0.16 11.1 3.1 0.2 10.8 3.1 1.1 1 0 0 1 1 1 0 Fumble MCU PF04678.13 EGG14721.1 - 0.23 11.5 8.8 0.34 11.0 8.8 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter V_ATPase_I PF01496.19 EGG14721.1 - 1 7.2 16.1 1.2 7.0 16.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4446 PF14584.6 EGG14721.1 - 1.6 8.7 9.2 2.7 8.0 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Allexi_40kDa PF05549.11 EGG14721.1 - 3 7.3 14.7 4.1 6.8 14.7 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein LMBR1 PF04791.16 EGG14721.1 - 3 6.6 8.0 3.3 6.5 8.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ERM PF00769.19 EGG14721.1 - 8.8 6.1 30.2 11 5.7 30.2 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family YPEB PF14620.6 EGG14721.1 - 8.9 5.5 24.2 11 5.2 24.2 1.1 1 0 0 1 1 1 0 YpeB sporulation PH PF00169.29 EGG14722.1 - 1.8e-11 44.4 0.2 5.3e-11 43.0 0.2 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGG14722.1 - 6.7e-09 36.1 1.2 6.7e-09 36.1 1.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_12 PF16457.5 EGG14722.1 - 0.00018 22.1 1.6 0.00018 22.1 1.6 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 EGG14722.1 - 0.0065 16.6 0.3 4.3 7.5 0.0 2.8 2 0 0 2 2 2 2 PH domain WD40 PF00400.32 EGG14722.1 - 0.028 15.3 0.0 0.37 11.7 0.0 3.1 1 0 0 1 1 1 0 WD domain, G-beta repeat SWI-SNF_Ssr4 PF08549.10 EGG14722.1 - 1.2 7.7 4.1 1.7 7.1 4.1 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) NDT80_PhoG PF05224.12 EGG14723.1 - 4.2e-27 95.6 0.0 4.2e-27 95.6 0.0 3.5 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.6 EGG14723.1 - 6.7e-09 35.9 0.1 1.5e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase MRF_C1 PF13887.6 EGG14723.1 - 0.0023 17.0 0.0 0.0042 16.2 0.0 1.4 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 Sigma_reg_N PF13800.6 EGG14723.1 - 0.012 15.9 0.0 0.047 14.0 0.0 2.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ETRAMP PF09716.10 EGG14723.1 - 0.021 14.9 0.0 0.25 11.4 0.0 2.7 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) FixO PF02433.15 EGG14723.1 - 0.13 11.7 3.0 0.31 10.5 3.0 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF4834 PF16118.5 EGG14723.1 - 0.32 12.0 23.3 1.4 9.9 0.0 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 EGG14723.1 - 1.3 9.9 3.5 36 5.3 0.0 3.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TNFR_16_TM PF18422.1 EGG14723.1 - 2.4 8.2 4.1 8.8 6.4 4.1 2.0 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain tRNA-synt_2b PF00587.25 EGG14724.1 - 1.4e-34 119.6 0.0 2.9e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGG14724.1 - 3.5e-20 72.0 0.4 6.6e-20 71.1 0.4 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EGG14724.1 - 3.4e-13 49.5 0.0 6.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EGG14724.1 - 2.9e-12 46.5 0.0 6.9e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 TGS domain RhoGEF PF00621.20 EGG14725.1 - 9.1e-67 224.8 18.3 2.3e-48 164.8 2.5 2.7 3 0 0 3 3 3 2 RhoGEF domain RhoGAP PF00620.27 EGG14725.1 - 1.4e-34 119.2 2.1 2.7e-33 114.9 0.6 2.9 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.6 EGG14725.1 - 2.5e-12 46.5 0.1 4.3e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGG14725.1 - 3.4e-11 42.6 0.0 6.2e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG14725.1 - 4e-08 32.8 0.0 9e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain KAP PF05804.12 EGG14725.1 - 0.016 13.4 3.2 0.17 10.0 0.2 2.1 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) DUF1708 PF08101.11 EGG14725.1 - 0.04 13.1 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) SMP_2 PF10144.9 EGG14725.1 - 0.12 12.1 0.5 0.29 10.8 0.5 1.6 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin Coiled PF05710.12 EGG14726.1 - 0.0063 17.3 2.5 0.0071 17.1 2.5 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 EGG14727.1 - 0.0015 19.3 3.0 0.0016 19.2 3.0 1.1 1 0 0 1 1 1 1 Coiled coil Pkinase PF00069.25 EGG14728.1 - 4.4e-45 154.1 8.1 3.9e-26 92.0 0.2 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG14728.1 - 3.8e-19 69.0 0.0 9.6e-14 51.3 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EGG14728.1 - 0.00073 18.9 0.6 0.004 16.5 0.2 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG14728.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family CN_hydrolase PF00795.22 EGG14729.1 - 2e-57 194.5 0.0 2.4e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GCFC PF07842.12 EGG14730.1 - 4.6e-49 167.5 8.9 4.6e-49 167.5 8.9 1.9 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EGG14730.1 - 6e-05 22.8 0.5 0.00018 21.3 0.5 1.8 1 0 0 1 1 1 1 G-patch domain 3-HAO PF06052.12 EGG14731.1 - 8.3e-59 197.6 0.1 9.5e-59 197.4 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EGG14731.1 - 4.3e-06 26.4 0.0 6.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EGG14731.1 - 0.0037 16.9 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 EGG14731.1 - 0.017 15.3 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Nudix_N_2 PF14803.6 EGG14731.1 - 0.027 14.4 0.3 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Nudix N-terminal AraC_binding PF02311.19 EGG14731.1 - 0.078 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_6 PF12852.7 EGG14731.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Cupin Pro-kuma_activ PF09286.11 EGG14732.1 - 1e-27 97.1 0.0 2.8e-27 95.7 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGG14732.1 - 5.7e-06 25.8 0.0 9.5e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Gelsolin PF00626.22 EGG14733.1 - 6.4e-41 138.1 3.3 3.9e-11 42.7 0.0 5.7 5 1 0 5 5 5 5 Gelsolin repeat VHP PF02209.19 EGG14733.1 - 2.7e-12 46.5 1.5 5.5e-12 45.6 1.5 1.6 1 0 0 1 1 1 1 Villin headpiece domain COG4 PF08318.12 EGG14734.1 - 1.2e-41 143.0 11.0 3.8e-40 138.0 11.0 2.4 1 1 0 1 1 1 1 COG4 transport protein THF_DHG_CYH_C PF02882.19 EGG14735.1 - 8.7e-54 181.2 0.2 1.5e-53 180.4 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EGG14735.1 - 4.7e-31 107.5 0.3 7.6e-31 106.8 0.3 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF1899 PF08953.11 EGG14736.1 - 9.9e-14 51.0 0.1 2e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EGG14736.1 - 2.1e-12 46.7 0.1 4e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EGG14736.1 - 1.3e-07 32.2 6.6 0.00092 20.0 0.2 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG14736.1 - 2.2e-05 24.7 0.0 0.0023 18.2 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG14736.1 - 0.0038 15.9 0.1 0.036 12.7 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 zf-C3HC4_3 PF13920.6 EGG14738.1 - 2.9e-09 36.7 7.6 5.1e-09 35.8 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG14738.1 - 4.6e-07 29.7 12.9 9.5e-07 28.7 12.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-CCCH PF00642.24 EGG14738.1 - 5.1e-06 26.3 0.6 5.1e-06 26.3 0.6 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.6 EGG14738.1 - 5.1e-06 26.4 6.8 5.1e-06 26.4 6.8 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 EGG14738.1 - 1.9e-05 24.6 1.3 1.9e-05 24.6 1.3 2.7 3 0 0 3 3 2 1 Zinc finger domain zf-RING_2 PF13639.6 EGG14738.1 - 2.6e-05 24.4 10.4 2.6e-05 24.4 10.4 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG14738.1 - 2.9e-05 23.8 12.3 6.6e-05 22.7 12.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG14738.1 - 6.9e-05 22.6 12.8 0.00016 21.5 12.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 EGG14738.1 - 0.00057 19.6 0.4 0.00057 19.6 0.4 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 EGG14738.1 - 0.0057 16.8 9.8 0.017 15.3 9.8 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGG14738.1 - 0.0059 16.5 9.1 0.012 15.4 9.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGG14738.1 - 0.024 14.8 5.3 0.024 14.8 5.3 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-Nse PF11789.8 EGG14738.1 - 0.028 14.2 6.7 0.065 13.1 6.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2685 PF10886.8 EGG14738.1 - 0.18 12.0 1.1 9.2 6.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) zf-RING_6 PF14835.6 EGG14738.1 - 0.18 11.7 1.3 0.39 10.6 1.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 EGG14738.1 - 4.1 7.1 8.2 15 5.4 8.2 1.9 1 1 0 1 1 1 0 P-11 zinc finger O-antigen_lig PF13425.6 EGG14738.1 - 9.4 4.9 8.2 13 4.4 8.2 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF1990 PF09348.10 EGG14739.1 - 7.4e-47 159.2 0.0 1e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) Coiled PF05710.12 EGG14740.1 - 0.0002 22.1 10.7 0.00029 21.6 10.7 1.3 1 1 0 1 1 1 1 Coiled coil DUF2722 PF10846.8 EGG14742.1 - 0.029 13.3 5.7 0.032 13.2 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) WBP-1 PF11669.8 EGG14742.1 - 3.3 8.4 7.5 6.1 7.5 7.5 1.4 1 1 0 1 1 1 0 WW domain-binding protein 1 Glucosamine_iso PF01182.20 EGG14743.1 - 4.9e-20 72.4 0.0 6.7e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF4191 PF13829.6 EGG14744.1 - 0.038 13.3 0.2 0.055 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) SecE PF00584.20 EGG14744.1 - 0.082 12.8 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Spt20 PF12090.8 EGG14744.1 - 5.6 6.5 17.1 8.7 5.9 17.1 1.3 1 0 0 1 1 1 0 Spt20 family Helo_like_N PF17111.5 EGG14745.1 - 0.02 14.3 0.8 0.053 12.9 0.8 1.7 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DDE_Tnp_1_7 PF13843.6 EGG14747.1 - 1.3e-13 51.0 0.1 1e-12 48.0 0.1 2.1 1 1 0 1 1 1 1 Transposase IS4 NPR2 PF06218.11 EGG14751.1 - 0.11 11.3 0.8 0.14 10.9 0.8 1.0 1 0 0 1 1 1 0 Nitrogen permease regulator 2 FAM60A PF15396.6 EGG14754.1 - 1.1 9.2 7.2 1.3 9.0 7.2 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF3552 PF12072.8 EGG14755.1 - 0.036 13.5 6.6 0.044 13.2 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1068 PF06364.12 EGG14755.1 - 0.087 12.7 0.8 0.1 12.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Peptidase_C48 PF02902.19 EGG14756.1 - 1.4e-06 28.3 0.7 2e-06 27.8 0.6 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain OSCP PF00213.18 EGG14756.1 - 0.078 13.1 1.4 0.14 12.3 1.4 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit M-inducer_phosp PF06617.13 EGG14757.1 - 0.012 15.0 0.3 0.017 14.4 0.3 1.2 1 0 0 1 1 1 0 M-phase inducer phosphatase Cyt-b5 PF00173.28 EGG14758.1 - 5e-09 36.2 0.0 7.4e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MGC-24 PF05283.11 EGG14758.1 - 0.00096 19.6 1.9 0.0011 19.5 1.9 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin MSA-2c PF12238.8 EGG14758.1 - 0.0065 16.5 3.0 0.0076 16.3 3.0 1.1 1 0 0 1 1 1 1 Merozoite surface antigen 2c EST1 PF10374.9 EGG14758.1 - 0.021 15.5 0.1 0.024 15.3 0.1 1.1 1 0 0 1 1 1 0 Telomerase activating protein Est1 ATP11 PF06644.11 EGG14758.1 - 0.055 13.3 0.8 0.067 13.0 0.8 1.1 1 0 0 1 1 1 0 ATP11 protein MCPVI PF02993.14 EGG14758.1 - 0.13 12.0 3.7 0.19 11.5 3.7 1.3 1 1 0 1 1 1 0 Minor capsid protein VI SSP160 PF06933.11 EGG14758.1 - 0.25 9.5 12.2 0.28 9.4 12.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 EssA PF10661.9 EGG14758.1 - 0.5 10.2 5.3 1.5 8.7 5.3 1.8 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA SR-25 PF10500.9 EGG14758.1 - 0.75 9.4 14.7 0.89 9.1 14.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 EGG14758.1 - 0.95 7.7 6.7 1.1 7.5 6.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 EGG14758.1 - 4.8 5.6 6.8 5.1 5.5 6.8 1.0 1 0 0 1 1 1 0 Macoilin family EXS PF03124.14 EGG14759.1 - 5.4e-73 246.2 31.6 7.4e-73 245.7 31.6 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EGG14759.1 - 3.6e-26 93.0 25.5 9.3e-15 55.4 11.8 2.3 1 1 1 2 2 2 2 SPX domain ThiF PF00899.21 EGG14761.1 - 2.3e-16 59.9 0.0 8.6e-16 58.0 0.0 2.4 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 EGG14761.1 - 1.9e-07 31.1 0.1 0.0099 16.0 0.0 3.6 3 0 0 3 3 3 2 Ubiquitin-activating enzyme E1 four-helix bundle Peptidase_C48 PF02902.19 EGG14762.1 - 2.3e-13 50.5 0.2 4.1e-13 49.7 0.2 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Dickkopf_N PF04706.12 EGG14764.1 - 0.0015 19.0 2.3 0.0015 19.0 2.3 7.0 3 2 4 8 8 8 3 Dickkopf N-terminal cysteine-rich region BTB PF00651.31 EGG14765.1 - 1.9e-15 57.1 0.0 6.4e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 EGG14765.1 - 3.5e-06 27.0 0.1 2e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch SAPS PF04499.15 EGG14765.1 - 0.0055 15.6 5.6 0.0081 15.0 5.6 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein VIT PF08487.10 EGG14768.1 - 8.7e-30 103.2 0.0 1.7e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EGG14768.1 - 2e-25 89.5 0.0 4e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EGG14768.1 - 6.1e-10 39.6 0.0 1.5e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGG14768.1 - 4.1e-07 30.6 0.0 1.3e-06 29.0 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EGG14768.1 - 0.0001 22.1 0.4 0.00022 21.0 0.4 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain ELMO_CED12 PF04727.13 EGG14769.1 - 3.7e-26 92.3 0.0 3.7e-26 92.3 0.0 3.0 3 0 0 3 3 3 1 ELMO/CED-12 family BTV_NS2 PF04514.12 EGG14770.1 - 0.32 9.8 5.3 0.34 9.7 5.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1120 PF06551.12 EGG14770.1 - 2.1 8.5 5.9 1.1 9.4 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1120) Vfa1 PF08432.10 EGG14770.1 - 5.6 7.2 9.8 6.5 7.1 9.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CAP PF00188.26 EGG14771.1 - 3.9e-13 50.3 0.5 3.9e-13 50.3 0.5 2.4 3 0 0 3 3 3 1 Cysteine-rich secretory protein family DUF3439 PF11921.8 EGG14772.1 - 0.3 11.0 2.9 0.75 9.8 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Phosphodiest PF01663.22 EGG14773.1 - 1.7e-20 73.9 2.8 3.2e-09 36.8 0.2 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EGG14773.1 - 7.7e-09 35.3 0.8 0.0011 18.4 0.1 2.3 2 0 0 2 2 2 2 Metalloenzyme superfamily Baculo_11_kDa PF06143.11 EGG14773.1 - 0.019 14.5 7.9 2.7 7.6 1.1 4.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family Aromatic_hydrox PF11723.8 EGG14773.1 - 0.046 13.2 0.0 6.9 6.1 0.0 2.5 2 0 0 2 2 2 0 Homotrimeric ring hydroxylase PglZ PF08665.12 EGG14773.1 - 2.5 8.2 12.6 66 3.5 0.2 5.7 6 0 0 6 6 6 0 PglZ domain DUF1056 PF06341.11 EGG14773.1 - 2.9 8.3 12.3 11 6.4 2.8 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) DUF5109 PF17134.4 EGG14774.1 - 0.022 14.7 2.8 2.4 8.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5109) MlaC PF05494.12 EGG14774.1 - 0.039 13.7 0.4 4.6 7.0 0.1 2.6 2 0 0 2 2 2 0 MlaC protein HECW1_helix PF18436.1 EGG14774.1 - 0.091 12.9 1.7 64 3.8 0.0 4.8 4 0 0 4 4 4 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 Rad10 PF03834.14 EGG14774.1 - 0.13 12.3 3.1 2.3 8.2 0.2 2.8 2 0 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Lep_receptor_Ig PF06328.11 EGG14774.1 - 0.21 11.5 1.8 0.66 10.0 1.8 1.8 1 0 0 1 1 1 0 Ig-like C2-type domain HTH_AraC PF00165.23 EGG14774.1 - 0.87 9.8 4.3 20 5.4 0.2 3.2 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family Tsg PF04668.12 EGG14774.1 - 3.1 8.5 9.2 12 6.6 1.1 2.9 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region Spt20 PF12090.8 EGG14774.1 - 6.9 6.2 21.9 0.063 12.9 5.1 2.8 3 0 0 3 3 3 0 Spt20 family Glyco_hydro_25 PF01183.20 EGG14775.1 - 6.1e-07 29.8 0.0 7.6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Pkinase PF00069.25 EGG14776.1 - 8.6e-67 225.3 0.1 1.1e-66 224.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG14776.1 - 2.4e-48 164.7 0.0 3.4e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EGG14776.1 - 1.3e-21 77.1 0.4 3e-21 75.9 0.4 1.7 1 0 0 1 1 1 1 PH domain PBD PF00786.28 EGG14776.1 - 2.9e-14 53.1 0.0 7.7e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EGG14776.1 - 3.4e-06 26.1 0.0 5.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGG14776.1 - 0.0011 18.3 0.1 0.0045 16.3 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGG14776.1 - 0.016 14.2 0.4 0.049 12.6 0.4 1.7 1 1 0 1 1 1 0 Haspin like kinase domain DUF1491 PF07372.12 EGG14776.1 - 0.028 14.8 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) PH_8 PF15409.6 EGG14776.1 - 0.052 13.8 0.4 0.16 12.3 0.4 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 EGG14776.1 - 0.054 13.9 0.5 0.46 10.9 0.5 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain DUF1160 PF06648.11 EGG14776.1 - 0.062 13.3 0.4 0.22 11.5 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1160) PH_17 PF18012.1 EGG14776.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 PH domain PH_11 PF15413.6 EGG14776.1 - 0.16 12.4 9.1 2.1 8.8 5.3 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain HSP90 PF00183.18 EGG14777.1 - 2.5e-96 323.6 12.1 8.5e-93 312.0 7.7 2.4 2 1 1 3 3 3 2 Hsp90 protein HATPase_c_3 PF13589.6 EGG14777.1 - 1.7e-10 40.9 0.6 5.1e-10 39.3 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGG14777.1 - 2.5e-09 37.6 0.1 6.5e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3887 PF13026.6 EGG14777.1 - 0.00083 20.1 1.4 1.7 9.5 0.1 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3887) DUF4254 PF14063.6 EGG14777.1 - 0.05 13.4 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Herpes_PAP PF03325.13 EGG14777.1 - 0.43 10.1 3.1 0.19 11.3 0.1 1.9 2 0 0 2 2 2 0 Herpesvirus polymerase accessory protein CBFD_NFYB_HMF PF00808.23 EGG14778.1 - 4.3e-20 71.8 0.1 7.3e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGG14778.1 - 5.9e-10 39.6 2.7 5.9e-10 39.6 2.7 2.8 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 RRM_1 PF00076.22 EGG14781.1 - 1.1e-18 66.8 0.8 4.2e-12 45.7 0.3 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG14781.1 - 0.013 15.3 0.0 4 7.4 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif PAP2 PF01569.21 EGG14782.1 - 2.6e-07 30.5 2.9 9.5e-07 28.7 2.9 2.0 1 0 0 1 1 1 1 PAP2 superfamily MutS_V PF00488.21 EGG14783.1 - 4.8e-44 150.6 0.1 8.4e-44 149.9 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGG14783.1 - 3.7e-29 102.3 0.3 1.5e-28 100.3 0.1 2.1 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EGG14783.1 - 0.0013 19.1 0.1 0.0057 17.0 0.1 2.3 1 0 0 1 1 1 1 MutS family domain IV AAA_22 PF13401.6 EGG14783.1 - 0.26 11.6 3.2 6.5 7.0 0.0 3.9 4 1 0 4 4 4 0 AAA domain FKBP_C PF00254.28 EGG14784.1 - 1.3e-32 112.0 0.0 5.8e-31 106.7 0.0 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EGG14784.1 - 6.4e-15 55.6 0.0 6.4e-15 55.6 0.0 2.0 2 1 0 2 2 1 1 Nucleoplasmin-like domain YL1 PF05764.13 EGG14784.1 - 1e-06 29.1 7.2 1.4e-06 28.6 7.2 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Sigma70_ner PF04546.13 EGG14784.1 - 0.011 15.7 8.9 0.014 15.2 8.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 EGG14784.1 - 0.027 12.8 4.7 0.032 12.5 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGG14784.1 - 0.03 12.6 13.9 0.036 12.3 13.9 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EGG14784.1 - 0.054 12.9 12.0 0.07 12.6 12.0 1.1 1 0 0 1 1 1 0 SDA1 p25-alpha PF05517.12 EGG14784.1 - 0.13 12.5 3.1 0.77 9.9 0.0 2.4 1 1 1 2 2 2 0 p25-alpha Lin-8 PF03353.15 EGG14784.1 - 0.23 11.0 5.6 0.29 10.7 5.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIF_alpha PF05793.12 EGG14784.1 - 1.1 7.7 12.9 1.8 7.1 12.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 EGG14784.1 - 1.5 6.8 21.2 2 6.4 21.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3381 PF11861.8 EGG14784.1 - 2 8.2 10.5 3.5 7.4 10.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) BTV_NS2 PF04514.12 EGG14784.1 - 3.6 6.3 9.0 5.8 5.6 9.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 NOA36 PF06524.12 EGG14784.1 - 4 6.7 11.0 6.2 6.1 11.0 1.2 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 EGG14784.1 - 9.4 4.6 9.4 12 4.3 9.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 UCH PF00443.29 EGG14786.1 - 4.5e-48 164.0 14.2 4.5e-48 164.0 14.2 3.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG14786.1 - 6.6e-23 81.8 20.0 6.6e-23 81.8 20.0 4.2 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase TrbI PF03743.14 EGG14786.1 - 0.14 12.0 1.6 0.22 11.3 0.2 1.9 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein DUF2052 PF09747.9 EGG14786.1 - 2.2 8.4 45.7 0.057 13.5 6.5 4.6 3 1 0 4 4 4 0 Coiled-coil domain containing protein (DUF2052) Tim54 PF11711.8 EGG14786.1 - 8.2 5.1 27.5 1.2 7.8 2.4 3.8 4 0 0 4 4 4 0 Inner membrane protein import complex subunit Tim54 EGF_2 PF07974.13 EGG14787.1 - 0.086 13.2 30.4 0.74 10.2 12.0 2.7 2 0 0 2 2 2 0 EGF-like domain SKG6 PF08693.10 EGG14787.1 - 0.12 11.8 2.3 0.23 10.9 2.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3844 PF12955.7 EGG14787.1 - 0.44 10.7 11.6 0.22 11.7 1.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) DUF3042 PF11240.8 EGG14787.1 - 1 9.4 3.6 2.9 8.0 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Hormone_5 PF00184.17 EGG14787.1 - 5.5 7.9 14.5 5 8.0 0.8 2.5 2 0 0 2 2 2 0 Neurohypophysial hormones, C-terminal Domain TruB_N PF01509.18 EGG14789.1 - 7.7e-41 139.9 0.0 1.8e-40 138.8 0.0 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EGG14789.1 - 3.5e-06 27.1 0.2 7.9e-06 25.9 0.2 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Pkinase PF00069.25 EGG14790.1 - 2.5e-42 145.1 0.0 1.6e-14 54.0 0.0 4.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGG14790.1 - 4.2e-24 85.2 0.0 1.8e-09 37.3 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RVT_1 PF00078.27 EGG14790.1 - 1.4e-11 44.3 1.8 1.7e-07 31.0 0.1 2.8 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD PF12009.8 EGG14790.1 - 1.5e-10 41.3 8.6 9e-10 38.8 4.5 3.7 2 1 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain Flavin_Reduct PF01613.18 EGG14790.1 - 5.2e-08 33.1 0.3 1.4e-07 31.7 0.3 1.7 1 0 0 1 1 1 1 Flavin reductase like domain BUD22 PF09073.10 EGG14790.1 - 2.6 7.3 88.9 0.018 14.4 19.7 4.7 4 0 0 4 4 4 0 BUD22 MAD PF05557.13 EGG14791.1 - 3.8e-60 204.0 100.1 3.6e-36 124.8 7.0 3.0 1 1 2 3 3 3 3 Mitotic checkpoint protein CENP-F_leu_zip PF10473.9 EGG14791.1 - 0.00017 21.6 7.7 0.00017 21.6 7.7 7.5 2 2 5 7 7 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 EGG14791.1 - 0.0036 17.4 6.2 0.0036 17.4 6.2 7.3 2 2 3 6 6 6 2 Afadin- and alpha -actinin-Binding DUF2163 PF09931.9 EGG14791.1 - 0.017 15.3 0.2 0.079 13.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2163) SlyX PF04102.12 EGG14791.1 - 0.59 10.8 0.0 0.59 10.8 0.0 9.5 6 2 3 9 9 9 0 SlyX EB1 PF03271.17 EGG14792.1 - 9.3e-11 41.8 1.2 9.3e-11 41.8 1.2 3.1 3 1 0 3 3 3 1 EB1-like C-terminal motif CH PF00307.31 EGG14792.1 - 2.7e-09 37.2 0.3 1.7e-08 34.6 0.1 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain TFIIA PF03153.13 EGG14792.1 - 4.6e-05 23.6 18.3 6.3e-05 23.2 18.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 EGG14792.1 - 0.012 14.9 8.8 0.016 14.4 8.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CAMSAP_CH PF11971.8 EGG14792.1 - 0.017 15.0 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain DUF5547 PF17701.1 EGG14792.1 - 0.026 14.4 0.2 5.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5547) YTV PF07639.11 EGG14792.1 - 4.8 7.4 14.7 0.42 10.7 7.9 2.6 1 1 0 2 2 2 0 YTV RGS PF00615.19 EGG14793.1 - 1.8e-14 54.0 1.2 4.3e-10 39.9 0.6 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain TFIIA PF03153.13 EGG14793.1 - 2 8.3 13.5 0.092 12.7 8.0 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CstA_5TM PF13722.6 EGG14794.1 - 0.0023 18.3 0.0 0.0038 17.6 0.0 1.5 1 1 0 1 1 1 1 5TM C-terminal transporter carbon starvation CstA Nitr_red_assoc PF09655.10 EGG14794.1 - 0.0085 16.7 0.0 0.011 16.4 0.0 1.2 1 0 0 1 1 1 1 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Sec1 PF00995.23 EGG14795.1 - 4.6e-97 326.6 13.1 4.6e-97 326.6 13.1 2.0 2 0 0 2 2 2 1 Sec1 family ATG101 PF07855.12 EGG14796.1 - 3.8e-21 75.7 2.5 2e-20 73.4 2.5 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 UvrD-helicase PF00580.21 EGG14796.1 - 0.026 14.1 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SAM_PNT PF02198.16 EGG14797.1 - 0.00012 21.9 0.2 0.00018 21.4 0.2 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Hepsin-SRCR PF09272.10 EGG14797.1 - 0.074 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Hepsin, SRCR domain HSP20 PF00011.21 EGG14798.1 - 1.2e-12 47.8 0.0 1.7e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG14798.1 - 9.7e-05 21.9 0.0 0.00024 20.6 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 EGG14799.1 - 3e-16 59.4 0.1 5.1e-10 39.4 0.0 2.5 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG14799.1 - 0.005 16.4 0.0 0.024 14.2 0.0 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA RabGAP-TBC PF00566.18 EGG14800.1 - 3.4e-50 170.7 1.9 3.4e-50 170.7 1.9 3.4 3 1 0 3 3 3 1 Rab-GTPase-TBC domain PhoLip_ATPase_C PF16212.5 EGG14801.1 - 6e-91 304.6 26.0 6e-91 304.6 26.0 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGG14801.1 - 2.3e-31 107.3 1.7 8.4e-31 105.5 1.7 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EGG14801.1 - 2.5e-15 56.4 0.8 6.4e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGG14801.1 - 1.6e-10 40.9 0.0 1.8e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGG14801.1 - 1.5e-07 31.9 2.2 0.0093 16.3 2.3 4.0 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGG14801.1 - 0.00022 21.0 0.5 0.0062 16.3 0.1 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3671 PF12420.8 EGG14801.1 - 0.019 15.0 0.9 0.019 15.0 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function Methylase_S PF01420.19 EGG14801.1 - 0.079 13.2 4.8 2.4 8.3 0.0 3.2 3 0 0 3 3 3 0 Type I restriction modification DNA specificity domain Arf PF00025.21 EGG14802.1 - 2.8e-16 59.4 0.0 1e-15 57.6 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGG14802.1 - 0.0032 17.4 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 EGG14802.1 - 0.0035 16.7 0.0 0.0089 15.4 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family ABC_tran PF00005.27 EGG14802.1 - 0.0062 17.0 0.0 0.01 16.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGG14802.1 - 0.0074 16.1 0.1 0.41 10.4 0.1 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGG14802.1 - 0.008 16.3 0.0 0.014 15.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGG14802.1 - 0.034 14.4 0.0 0.065 13.5 0.0 1.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGG14802.1 - 0.038 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGG14802.1 - 0.053 14.0 0.0 0.09 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 EGG14802.1 - 0.073 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Ras PF00071.22 EGG14802.1 - 0.077 12.6 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Ras family AAA_14 PF13173.6 EGG14802.1 - 0.18 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EGG14802.1 - 0.23 11.0 0.0 1.4 8.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Glyco_hydro_65m PF03632.15 EGG14804.1 - 5.5e-26 91.3 0.0 1.8e-16 60.0 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain DUF2152 PF10222.9 EGG14804.1 - 3.3e-07 29.0 0.0 0.00015 20.2 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2152) Glyco_hydro_65N PF03636.15 EGG14804.1 - 0.00055 19.6 1.2 0.0012 18.5 1.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Beta-lactamase2 PF13354.6 EGG14804.1 - 0.053 13.1 0.2 0.12 11.9 0.1 1.5 1 1 0 1 1 1 0 Beta-lactamase enzyme family OmpH PF03938.14 EGG14805.1 - 0.001 19.4 8.5 0.0019 18.5 8.5 1.4 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Spt20 PF12090.8 EGG14805.1 - 0.0071 16.0 5.1 0.01 15.4 5.1 1.3 1 0 0 1 1 1 1 Spt20 family HI0933_like PF03486.14 EGG14805.1 - 0.042 12.6 1.9 0.059 12.1 1.9 1.2 1 0 0 1 1 1 0 HI0933-like protein DEAD_assoc PF08494.11 EGG14805.1 - 0.098 12.4 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 DEAD/H associated Cnd1 PF12717.7 EGG14805.1 - 0.17 11.9 8.4 11 6.0 3.6 3.1 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF2722 PF10846.8 EGG14805.1 - 0.19 10.6 4.9 0.27 10.2 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med3 PF11593.8 EGG14805.1 - 0.61 9.2 8.3 1 8.5 8.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3452 PF11934.8 EGG14806.1 - 0.0081 15.7 1.7 4 7.0 0.0 3.5 2 1 1 3 3 3 2 Domain of unknown function (DUF3452) THF_DHG_CYH PF00763.23 EGG14806.1 - 0.088 13.1 0.1 0.28 11.5 0.1 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain BP28CT PF08146.12 EGG14806.1 - 0.14 12.0 3.9 0.96 9.3 0.5 3.4 2 2 0 2 2 2 0 BP28CT (NUC211) domain CENP-B_dimeris PF09026.10 EGG14807.1 - 2.1 8.8 12.9 3 8.3 1.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Radial_spoke PF04712.12 EGG14807.1 - 2.8 6.8 15.0 0.9 8.4 0.4 2.5 3 0 0 3 3 3 0 Radial spokehead-like protein FAM176 PF14851.6 EGG14807.1 - 8.9 6.0 8.7 47 3.6 6.0 2.4 2 0 0 2 2 2 0 FAM176 family DDE_Tnp_4 PF13359.6 EGG14809.1 - 4.9e-24 84.8 0.0 1e-23 83.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 EGG14809.1 - 2.5e-09 36.7 0.2 5e-09 35.7 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGG14809.1 - 0.00037 20.2 0.2 0.0018 18.0 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain RR_TM4-6 PF06459.12 EGG14809.1 - 0.11 12.3 8.1 0.24 11.2 8.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 EGG14809.1 - 0.13 11.2 3.5 0.55 9.2 3.4 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EGG14809.1 - 0.16 10.7 4.2 0.25 10.1 4.2 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EGG14809.1 - 0.67 9.1 1.5 0.97 8.6 1.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 EGG14809.1 - 1.9 6.7 12.0 3.2 5.9 12.0 1.3 1 0 0 1 1 1 0 CDC45-like protein SUIM_assoc PF16619.5 EGG14810.1 - 0.0069 16.4 1.5 0.02 15.0 1.5 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF5601 PF18151.1 EGG14810.1 - 1.5 9.2 6.8 1 9.7 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) Radial_spoke PF04712.12 EGG14811.1 - 2.1 7.2 11.1 1.2 8.0 0.3 2.5 3 0 0 3 3 3 0 Radial spokehead-like protein CENP-B_dimeris PF09026.10 EGG14811.1 - 5.9 7.3 12.2 12 6.3 0.8 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DDE_Tnp_1_7 PF13843.6 EGG14812.1 - 1.1e-11 44.7 0.2 1.4e-11 44.3 0.2 1.1 1 0 0 1 1 1 1 Transposase IS4 PQ-loop PF04193.14 EGG14815.1 - 4.3e-25 87.2 12.2 1.8e-15 56.4 2.0 3.3 3 0 0 3 3 3 2 PQ loop repeat NnrS PF05940.12 EGG14815.1 - 0.074 12.4 3.6 0.091 12.1 3.6 1.1 1 0 0 1 1 1 0 NnrS protein WD40 PF00400.32 EGG14816.1 - 0.00015 22.5 10.8 0.014 16.3 0.1 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat UPF0183 PF03676.14 EGG14817.1 - 1.1e-107 360.7 5.9 5.1e-87 292.7 6.9 2.7 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) DUF2283 PF10049.9 EGG14818.1 - 6.4e-11 42.3 2.5 1e-10 41.7 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2283) Peptidase_S49_N PF08496.10 EGG14819.1 - 2.8 8.0 4.7 2.3 8.3 0.2 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Presenilin PF01080.17 EGG14819.1 - 3.1 6.5 8.3 5.8 5.6 4.2 2.3 2 0 0 2 2 2 0 Presenilin FAM176 PF14851.6 EGG14819.1 - 4.1 7.1 6.5 26 4.5 1.8 2.8 3 0 0 3 3 3 0 FAM176 family NTF2 PF02136.20 EGG14820.1 - 1.4e-10 41.7 0.0 3e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EGG14820.1 - 5.1e-06 26.2 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EGG14821.1 - 7.2e-05 23.5 8.4 18 6.4 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG14821.1 - 0.0027 18.0 0.3 2.4 8.5 0.1 3.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF167 PF02594.16 EGG14823.1 - 3.8e-22 78.2 0.0 5.4e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 DUF908 PF06012.12 EGG14824.1 - 0.076 12.4 6.2 0.11 11.9 6.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TPR_2 PF07719.17 EGG14825.1 - 3.2e-21 73.7 8.4 0.00091 19.2 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGG14825.1 - 4.9e-20 70.5 12.8 0.0097 15.7 0.1 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGG14825.1 - 2.3e-11 43.2 12.4 2.3e-06 27.2 0.1 5.0 5 0 0 5 5 5 3 TPR repeat TPR_16 PF13432.6 EGG14825.1 - 3.9e-10 40.2 0.1 0.086 13.5 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG14825.1 - 2.8e-08 33.9 2.3 0.48 10.7 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG14825.1 - 6.5e-08 32.2 7.4 1 9.7 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG14825.1 - 6.6e-07 29.6 0.1 0.083 13.8 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG14825.1 - 2e-06 27.9 0.0 0.59 10.3 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG14825.1 - 5.5e-05 23.3 0.7 0.0016 18.7 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG14825.1 - 8.1e-05 22.6 3.4 1.1 9.3 0.0 4.3 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 EGG14825.1 - 0.00087 19.8 0.7 8.5 7.0 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat SR-25 PF10500.9 EGG14825.1 - 0.003 17.2 16.3 0.003 17.2 16.3 5.0 5 0 0 5 5 5 1 Nuclear RNA-splicing-associated protein SHNi-TPR PF10516.9 EGG14825.1 - 0.025 14.0 0.1 33 4.0 0.0 4.1 5 0 0 5 5 5 0 SHNi-TPR TPR_7 PF13176.6 EGG14825.1 - 0.057 13.5 2.0 20 5.5 0.1 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat Ribosomal_60s PF00428.19 EGG14825.1 - 1.2 9.7 4.4 19 5.9 3.7 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_6 PF13174.6 EGG14825.1 - 3.7 8.4 5.8 12 6.8 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Macoilin PF09726.9 EGG14825.1 - 3.8 6.0 57.0 0.2 10.2 18.9 3.2 3 0 0 3 3 3 0 Macoilin family DUF3452 PF11934.8 EGG14826.1 - 0.018 14.6 6.4 0.14 11.7 0.5 3.5 2 2 2 4 4 4 0 Domain of unknown function (DUF3452) bacHORMA_2 PF18173.1 EGG14826.1 - 0.043 13.7 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial HORMA domain 2 Nrf1_activ_bdg PF10492.9 EGG14826.1 - 0.059 14.1 0.4 0.19 12.4 0.4 1.9 1 0 0 1 1 1 0 Nrf1 activator activation site binding domain Ric8 PF10165.9 EGG14828.1 - 4.9e-05 22.6 1.0 4.9e-05 22.6 1.0 1.5 1 1 1 2 2 2 1 Guanine nucleotide exchange factor synembryn Utp13 PF08625.11 EGG14828.1 - 0.058 13.3 1.0 0.13 12.2 1.0 1.6 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Ipi1_N PF12333.8 EGG14828.1 - 0.24 12.0 1.8 0.44 11.2 0.1 2.2 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DUF4506 PF14958.6 EGG14829.1 - 0.086 12.4 0.3 0.086 12.4 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4506) DUF2251 PF10008.9 EGG14829.1 - 0.098 12.8 0.7 0.34 11.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2251) Chlam_PMP PF02415.17 EGG14830.1 - 0.011 16.2 1.3 0.011 16.2 1.3 8.9 8 2 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Podoplanin PF05808.11 EGG14830.1 - 0.18 11.9 9.9 0.39 10.8 9.9 1.6 1 0 0 1 1 1 0 Podoplanin Pex2_Pex12 PF04757.14 EGG14831.1 - 0.69 9.5 9.9 0.03 13.9 2.0 2.6 3 0 0 3 3 3 0 Pex2 / Pex12 amino terminal region DUF2615 PF11027.8 EGG14831.1 - 4.6 7.4 10.3 0.6 10.3 3.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Secretin_N_2 PF07655.13 EGG14831.1 - 6.9 7.3 25.5 32 5.1 20.7 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain PITH PF06201.13 EGG14832.1 - 3.1e-32 111.9 0.0 4.2e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 PITH domain PLDc PF00614.22 EGG14833.1 - 2.9e-19 68.4 0.9 1.2e-08 34.8 0.1 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGG14833.1 - 4.7e-12 45.9 2.5 4.7e-09 36.2 1.2 3.5 3 1 0 3 3 3 2 PLD-like domain NatB_MDM20 PF09797.9 EGG14834.1 - 4.3e-83 279.4 9.5 4.3e-83 279.4 9.5 2.2 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 EGG14834.1 - 2.3e-07 31.2 0.4 5.1e-06 26.9 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG14834.1 - 0.015 15.5 6.7 0.091 13.0 0.3 4.2 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGG14834.1 - 0.025 14.6 0.4 5.2 7.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGG14834.1 - 0.069 13.0 0.1 20 5.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGG14834.1 - 0.14 12.9 0.0 0.89 10.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PX PF00787.24 EGG14834.1 - 0.32 11.0 4.2 6.4 6.8 0.0 3.2 3 1 0 3 3 3 0 PX domain TPD52 PF04201.15 EGG14834.1 - 0.44 10.1 3.5 1 9.0 0.2 3.0 3 0 0 3 3 3 0 Tumour protein D52 family ATP-synt_G PF04718.15 EGG14834.1 - 1.3 9.9 7.3 9 7.2 0.0 4.6 5 0 0 5 5 5 0 Mitochondrial ATP synthase g subunit Cgr1 PF03879.14 EGG14836.1 - 2.4e-09 37.5 14.9 2.4e-09 37.5 14.9 3.6 3 1 0 3 3 3 2 Cgr1 family Ras PF00071.22 EGG14837.1 - 1.4e-57 193.8 0.3 1.7e-57 193.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG14837.1 - 7.3e-32 110.1 0.1 1.7e-31 108.9 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG14837.1 - 8.9e-13 48.1 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG14837.1 - 5.3e-06 26.5 0.0 1.7e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG14837.1 - 0.00012 21.7 0.1 0.00019 21.0 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGG14837.1 - 0.0029 17.0 0.0 0.004 16.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EGG14837.1 - 0.0094 16.3 0.0 0.031 14.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 EGG14837.1 - 0.012 15.2 0.4 2.1 7.9 0.2 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 EGG14837.1 - 0.023 14.7 0.1 0.23 11.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain AKAP7_NLS PF10469.9 EGG14837.1 - 0.025 14.5 0.3 0.032 14.1 0.3 1.2 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain AAA_28 PF13521.6 EGG14837.1 - 0.064 13.5 0.1 0.85 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGG14837.1 - 0.11 12.8 0.1 0.6 10.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain UPF0270 PF06794.12 EGG14837.1 - 0.11 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) WD40 PF00400.32 EGG14838.1 - 6.2e-30 102.8 23.3 2e-05 25.2 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG14838.1 - 0.00052 20.3 0.7 1.3 9.4 0.1 3.3 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1921 PF09081.10 EGG14838.1 - 0.072 13.3 0.0 9.7 6.5 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1921) Ank_2 PF12796.7 EGG14840.1 - 1.1e-06 29.1 3.5 0.18 12.4 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG14840.1 - 5.5e-05 23.6 0.1 10 6.9 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG14840.1 - 0.00022 21.4 4.5 7.2 7.5 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat DUF2639 PF11121.8 EGG14840.1 - 0.061 13.4 0.2 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) Ank_5 PF13857.6 EGG14840.1 - 0.17 12.3 4.4 4 7.9 0.0 4.3 5 0 0 5 5 5 0 Ankyrin repeats (many copies) zf-CSL PF05207.13 EGG14841.1 - 1.1e-22 79.5 1.7 2.3e-22 78.5 1.7 1.6 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.15 EGG14841.1 - 0.12 12.6 0.2 0.27 11.5 0.2 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain Ribosomal_L35p PF01632.19 EGG14842.1 - 0.00032 21.1 3.6 0.0005 20.5 3.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L35 FecR PF04773.13 EGG14842.1 - 0.095 13.3 0.1 0.12 13.1 0.1 1.1 1 0 0 1 1 1 0 FecR protein Nop14 PF04147.12 EGG14843.1 - 1.5 7.0 33.9 0.25 9.5 28.7 2.0 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 EGG14843.1 - 2.2 7.6 32.3 0.28 10.6 26.1 2.1 2 0 0 2 2 2 0 SDA1 DNA_pol_A PF00476.20 EGG14844.1 - 1.1e-54 186.0 0.1 3.8e-29 101.9 1.2 2.3 1 1 1 2 2 2 2 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EGG14844.1 - 0.016 15.0 1.1 0.021 14.5 0.1 1.7 2 0 0 2 2 2 0 3'-5' exonuclease PAPS_reduct PF01507.19 EGG14844.1 - 0.43 10.6 3.2 0.28 11.2 0.2 2.2 3 1 0 3 3 3 0 Phosphoadenosine phosphosulfate reductase family EGF_2 PF07974.13 EGG14845.1 - 0.0016 18.8 7.1 0.0042 17.4 7.1 1.7 1 0 0 1 1 1 1 EGF-like domain DUF1131 PF06572.12 EGG14845.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) LMBR1 PF04791.16 EGG14846.1 - 3.1 6.6 14.4 3.7 6.3 14.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein SpecificRecomb PF10136.9 EGG14846.1 - 4.9 5.3 7.7 0.43 8.8 0.5 1.9 1 1 1 2 2 2 0 Site-specific recombinase Lipase_GDSL PF00657.22 EGG14847.1 - 9.2e-10 38.8 0.0 1.6e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 EGG14848.1 - 8.4e-39 133.5 8.8 2.8e-38 131.8 8.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TPR_2 PF07719.17 EGG14850.1 - 0.0031 17.5 0.3 0.086 13.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC_CDC26 PF10471.9 EGG14851.1 - 3.9e-11 43.6 5.2 4.6e-11 43.4 5.2 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 TPR_1 PF00515.28 EGG14852.1 - 1.4e-21 75.4 2.7 1.4e-05 24.7 0.0 4.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGG14852.1 - 5e-18 63.7 1.0 0.00046 20.1 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGG14852.1 - 8.1e-11 41.5 0.4 0.0087 16.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG14852.1 - 1.5e-10 40.6 0.5 0.00086 18.9 0.0 4.4 3 1 1 4 4 4 3 TPR repeat TPR_8 PF13181.6 EGG14852.1 - 1e-09 37.8 0.2 0.019 15.2 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG14852.1 - 9e-09 35.7 0.4 5.6e-06 26.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG14852.1 - 1.4e-07 31.6 0.1 0.52 11.1 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG14852.1 - 1.6e-07 31.5 0.1 0.16 12.8 0.0 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG14852.1 - 1.3e-06 29.0 0.0 0.002 18.7 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG14852.1 - 2.5e-06 27.1 0.1 0.13 12.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG14852.1 - 4.9e-05 23.4 0.0 0.00048 20.2 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG14852.1 - 0.00019 21.7 0.7 1.4 9.2 0.0 3.8 3 2 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG14852.1 - 0.00058 20.0 0.7 0.26 11.6 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGG14852.1 - 0.059 13.3 0.3 2.4 8.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ras PF00071.22 EGG14853.1 - 3.6e-55 186.0 0.0 4.2e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG14853.1 - 1.1e-22 80.5 0.0 1.6e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG14853.1 - 1.6e-10 40.8 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG14853.1 - 0.0001 21.9 0.1 0.0004 20.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FNIP PF05725.12 EGG14854.1 - 0.088 13.0 14.5 3 8.1 0.4 6.6 4 3 3 7 7 7 0 FNIP Repeat DUF4848 PF16140.5 EGG14855.1 - 0.092 12.3 2.6 1.5 8.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4848) Orthopox_A49R PF06489.11 EGG14855.1 - 0.11 12.7 8.5 0.29 11.4 1.3 2.8 2 1 1 3 3 3 0 Orthopoxvirus A49R protein Phytochelatin PF05023.14 EGG14857.1 - 1.5e-90 302.1 0.1 6.7e-90 300.0 0.0 2.1 2 0 0 2 2 2 1 Phytochelatin synthase Pro_isomerase PF00160.21 EGG14857.1 - 3e-07 30.8 0.0 7.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Phytochelatin_C PF09328.10 EGG14857.1 - 4e-05 23.1 0.5 0.0013 18.1 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF1984) Peptidase_C39 PF03412.15 EGG14857.1 - 0.027 14.3 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Peptidase C39 family Zip PF02535.22 EGG14857.1 - 0.23 10.6 6.0 0.34 10.1 6.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MFMR_assoc PF16596.5 EGG14857.1 - 0.36 11.3 10.5 0.85 10.1 10.5 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR SH2 PF00017.24 EGG14858.1 - 1.1e-11 44.6 0.0 3e-08 33.7 0.0 3.0 2 0 0 2 2 2 2 SH2 domain LRR_6 PF13516.6 EGG14858.1 - 3.2e-10 39.2 2.5 0.00022 21.0 0.7 3.0 2 0 0 2 2 2 2 Leucine Rich repeat Macoilin PF09726.9 EGG14858.1 - 1.2 7.6 18.9 2 6.9 18.9 1.4 1 0 0 1 1 1 0 Macoilin family DUF4106 PF13388.6 EGG14859.1 - 4.5 6.4 21.7 6.3 5.9 21.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) NMT PF01233.19 EGG14860.1 - 3.5e-76 254.5 1.5 4e-76 254.3 0.2 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 EGG14860.1 - 1.1e-66 224.3 0.3 2.3e-66 223.3 0.3 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 EGG14860.1 - 0.0008 19.6 0.0 0.0045 17.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family AAA_lid_5 PF17865.1 EGG14860.1 - 0.072 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Midasin AAA lid domain Acetyltransf_7 PF13508.7 EGG14860.1 - 0.12 12.8 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG14860.1 - 0.2 11.6 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Flavokinase PF01687.17 EGG14861.1 - 1.2e-33 115.7 0.0 1.7e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase Clathrin PF00637.20 EGG14862.1 - 4.6e-12 46.0 17.5 6.9e-11 42.2 6.8 3.2 3 1 0 3 3 3 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 EGG14862.1 - 0.00025 20.6 3.3 0.00026 20.6 0.7 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 EGG14862.1 - 0.0003 21.1 1.9 0.0012 19.1 1.9 2.2 1 0 0 1 1 1 1 Ring finger domain Zf_RING PF16744.5 EGG14862.1 - 0.00041 20.4 0.4 0.0015 18.6 0.4 2.0 1 0 0 1 1 1 1 KIAA1045 RING finger DUF2175 PF09943.9 EGG14862.1 - 0.0008 19.7 0.0 0.0033 17.7 0.0 2.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_UBOX PF13445.6 EGG14862.1 - 0.00081 19.4 1.0 0.0023 17.9 1.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG14862.1 - 0.00089 19.2 2.2 0.0035 17.3 2.2 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGG14862.1 - 0.0026 17.6 4.6 0.003 17.4 2.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 EGG14862.1 - 0.0049 17.3 0.2 0.034 14.6 0.1 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 EGG14862.1 - 0.0061 16.6 2.4 0.019 15.0 2.4 1.9 1 0 0 1 1 1 1 Zinc-finger zf-RING_11 PF17123.5 EGG14862.1 - 0.013 15.2 3.7 0.045 13.5 3.7 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EGG14862.1 - 0.033 14.2 0.2 0.087 12.9 0.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGG14862.1 - 0.037 14.3 1.1 0.16 12.3 1.1 2.1 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGG14862.1 - 0.045 13.6 4.8 0.044 13.7 2.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DpnI_C PF17726.1 EGG14862.1 - 0.086 13.0 0.6 0.27 11.4 0.6 1.8 1 0 0 1 1 1 0 Dam-replacing HTH domain TPR_7 PF13176.6 EGG14862.1 - 1.3 9.2 4.3 43 4.5 0.0 4.3 4 2 0 4 4 3 0 Tetratricopeptide repeat TBP PF00352.21 EGG14864.1 - 0.17 11.8 0.0 7.6 6.6 0.0 2.0 2 0 0 2 2 2 0 Transcription factor TFIID (or TATA-binding protein, TBP) RelB_leu_zip PF16180.5 EGG14866.1 - 0.15 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 RelB leucine zipper RRM_1 PF00076.22 EGG14867.1 - 6.4e-09 35.5 0.2 1.4e-08 34.4 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EGG14869.1 - 0.0039 18.0 0.0 0.35 11.8 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGG14869.1 - 0.077 11.9 0.0 0.37 9.7 0.0 1.7 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mpv17_PMP22 PF04117.12 EGG14870.1 - 3.9e-21 75.0 3.2 1.2e-20 73.5 3.2 1.9 1 0 0 1 1 1 1 Mpv17 / PMP22 family G8 PF10162.9 EGG14871.1 - 4.6e-05 23.5 3.5 0.00018 21.6 0.2 3.1 2 1 1 3 3 3 2 G8 domain DUF3390 PF11870.8 EGG14872.1 - 0.023 15.1 0.1 0.074 13.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) DUF4972 PF16342.5 EGG14872.1 - 0.11 12.2 0.1 0.11 12.2 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4972) Kinesin PF00225.23 EGG14874.1 - 1.1e-110 369.7 4.5 1.1e-110 369.7 4.5 4.6 4 1 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EGG14874.1 - 1.5e-26 93.1 0.2 1.5e-26 93.1 0.2 4.1 3 0 0 3 3 3 1 Microtubule binding DUF4264 PF14084.6 EGG14874.1 - 0.00062 19.3 0.1 0.0021 17.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) AAA_22 PF13401.6 EGG14874.1 - 0.045 14.0 0.8 0.23 11.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma_reg_N PF13800.6 EGG14875.1 - 1 9.7 4.9 6.4 7.1 0.0 3.3 3 1 1 4 4 4 0 Sigma factor regulator N-terminal TMEM43 PF07787.12 EGG14875.1 - 1.9 7.8 3.6 0.38 10.1 0.2 1.6 2 0 0 2 2 2 0 Transmembrane protein 43 TcpE PF12648.7 EGG14875.1 - 5.8 7.5 6.4 3.2 8.3 0.1 2.5 2 0 0 2 2 2 0 TcpE family CD20 PF04103.15 EGG14876.1 - 0.012 15.8 7.1 0.51 10.4 2.3 2.6 2 0 0 2 2 2 0 CD20-like family Cas6_N PF17952.1 EGG14876.1 - 0.075 13.3 2.7 4.4 7.6 0.1 2.4 2 0 0 2 2 2 0 Cas6 N-terminal domain MTCP1 PF08991.10 EGG14876.1 - 0.27 11.5 2.7 2.9 8.2 0.4 2.4 2 0 0 2 2 2 0 Mature-T-Cell Proliferation I type DUF4064 PF13273.6 EGG14876.1 - 0.66 10.3 10.0 0.39 11.0 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) Ank_2 PF12796.7 EGG14877.1 - 6.9e-11 42.6 6.0 3.5e-07 30.7 0.3 5.2 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG14877.1 - 4.5e-06 26.6 1.2 10 7.1 0.0 5.7 3 1 2 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EGG14877.1 - 0.00018 22.0 1.9 0.012 16.2 0.0 4.6 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG14877.1 - 0.0041 17.4 0.3 0.12 12.7 0.0 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Presenilin PF01080.17 EGG14877.1 - 7 5.3 6.8 15 4.2 6.8 1.4 1 0 0 1 1 1 0 Presenilin eIF2A PF08662.11 EGG14878.1 - 3.5e-58 196.7 6.4 1.8e-54 184.6 1.2 4.1 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EGG14878.1 - 3.9e-06 27.1 0.0 0.45 10.8 0.0 5.2 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 EGG14878.1 - 0.00038 20.2 0.1 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.12 EGG14878.1 - 0.0035 15.4 0.0 0.0061 14.6 0.0 1.4 1 0 0 1 1 1 1 IKI3 family DUF866 PF05907.13 EGG14878.1 - 0.019 14.9 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) VioE PF18234.1 EGG14878.1 - 0.94 9.6 0.0 0.94 9.6 0.0 2.8 3 0 0 3 3 3 0 Violacein biosynthetic enzyme VioE Glyco_hydro_16 PF00722.21 EGG14879.1 - 4.3e-06 26.3 0.0 9.5e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TPR_1 PF00515.28 EGG14880.1 - 1.6e-34 116.3 33.7 8.5e-10 38.0 0.4 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 EGG14880.1 - 1.4e-32 109.2 28.7 4.3e-05 23.4 0.1 10.7 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 EGG14880.1 - 8.3e-32 106.7 26.4 3.8e-07 29.7 0.4 10.7 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.6 EGG14880.1 - 2.1e-23 82.4 12.5 9.2e-07 29.1 0.7 8.5 5 1 3 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGG14880.1 - 8e-22 77.6 0.0 2e-09 38.0 0.3 5.5 7 0 0 7 7 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG14880.1 - 2.7e-21 75.6 31.6 1.2e-08 35.1 0.2 7.1 6 2 2 8 8 8 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGG14880.1 - 7.4e-19 68.0 12.8 1.5e-05 25.4 2.3 7.4 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGG14880.1 - 6.3e-18 63.8 16.8 0.038 14.4 0.1 10.5 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGG14880.1 - 2.5e-16 59.1 18.2 0.00029 20.4 2.8 8.4 6 1 2 8 8 8 5 TPR repeat TPR_9 PF13371.6 EGG14880.1 - 1.5e-14 53.9 0.3 6.9e-06 26.1 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG14880.1 - 1.8e-14 53.2 3.6 0.6 11.1 0.0 9.1 4 2 6 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGG14880.1 - 2.7e-08 33.2 8.4 0.18 11.9 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG14880.1 - 1.1e-07 32.0 17.8 3.1 8.6 0.4 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGG14880.1 - 0.00031 20.5 20.8 5.1 7.1 0.0 9.1 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGG14880.1 - 0.00047 19.4 0.5 0.039 13.2 0.2 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 EGG14880.1 - 0.00072 18.6 14.4 0.023 13.6 0.0 4.3 3 1 2 5 5 5 3 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 EGG14880.1 - 0.0014 18.3 1.0 0.048 13.4 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 EGG14880.1 - 0.0076 16.3 9.5 0.015 15.3 1.3 4.4 4 1 0 4 4 4 1 Putative TPR-like repeat TPR_20 PF14561.6 EGG14880.1 - 0.11 12.9 4.0 0.057 13.8 0.6 2.4 2 0 0 2 2 1 0 Tetratricopeptide repeat PsaL PF02605.15 EGG14882.1 - 0.049 13.3 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI CwsA PF10814.8 EGG14882.1 - 0.17 12.1 0.1 0.21 11.8 0.1 1.2 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA LRR_4 PF12799.7 EGG14883.1 - 0.0023 18.3 3.8 0.013 15.9 0.3 3.1 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) HrpB7 PF09486.10 EGG14884.1 - 0.0011 19.3 18.2 0.0011 19.3 18.2 12.5 9 3 2 12 12 12 3 Bacterial type III secretion protein (HrpB7) Profilin PF00235.19 EGG14886.1 - 5.5e-16 59.0 0.4 6e-16 58.9 0.4 1.0 1 0 0 1 1 1 1 Profilin RNA_pol_Rpc82 PF05645.13 EGG14889.1 - 0.089 12.5 0.2 0.11 12.2 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 PQ-loop PF04193.14 EGG14890.1 - 1.1e-21 76.4 10.6 1.3e-11 44.1 4.2 2.5 2 0 0 2 2 2 2 PQ loop repeat NnrS PF05940.12 EGG14890.1 - 0.0032 16.9 4.2 0.0044 16.5 4.2 1.1 1 0 0 1 1 1 1 NnrS protein DUF3959 PF13105.6 EGG14890.1 - 0.12 11.8 1.3 0.23 10.9 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) BofA PF07441.11 EGG14890.1 - 0.59 10.4 7.4 0.11 12.7 2.7 2.2 2 1 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA DUF1422 PF07226.11 EGG14890.1 - 0.6 10.1 6.1 2.7 8.0 3.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1422) GMC_oxred_C PF05199.13 EGG14891.1 - 0.013 16.1 0.0 0.034 14.7 0.0 1.8 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox_2 PF07992.14 EGG14891.1 - 0.039 13.2 0.0 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BB_PF PF18063.1 EGG14892.1 - 3.4e-24 85.6 4.4 4.6e-24 85.2 4.4 1.2 1 0 0 1 1 1 1 Beta barrel Pore-forming domain Asn_synthase PF00733.21 EGG14893.1 - 1e-13 51.7 0.1 0.00037 20.3 0.0 3.3 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 EGG14893.1 - 1.1e-08 35.0 0.0 5e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain DDHD PF02862.17 EGG14893.1 - 0.0001 22.5 1.1 1.9 8.6 0.0 3.0 2 1 1 3 3 3 1 DDHD domain GATase_6 PF13522.6 EGG14893.1 - 0.0031 17.7 0.0 0.0096 16.1 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain FNIP PF05725.12 EGG14894.1 - 4.7e-18 65.1 14.5 5.1e-08 32.9 0.1 5.8 2 1 5 7 7 7 4 FNIP Repeat COMM_domain PF07258.14 EGG14895.1 - 4.5e-15 55.5 8.1 8.9e-15 54.6 8.1 1.5 1 0 0 1 1 1 1 COMM domain UPF0449 PF15136.6 EGG14895.1 - 0.45 11.0 5.8 1.7 9.2 5.8 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF4681 PF15732.5 EGG14895.1 - 1.2 9.4 5.2 2.4 8.4 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4681) Holin_BhlA PF10960.8 EGG14895.1 - 4.5 7.3 8.5 15 5.6 1.5 3.0 3 1 0 3 3 3 0 BhlA holin family Sedlin_N PF04628.13 EGG14896.1 - 5.5e-34 117.1 1.4 6.2e-34 116.9 1.4 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EGG14896.1 - 2.4e-05 24.3 1.1 2.7e-05 24.1 1.1 1.1 1 0 0 1 1 1 1 Sybindin-like family DUF5042 PF16445.5 EGG14896.1 - 0.02 13.3 0.1 0.024 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) Med9 PF07544.13 EGG14897.1 - 2.1e-07 30.9 2.4 2.1e-07 30.9 2.4 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF3391 PF11871.8 EGG14897.1 - 0.038 14.5 4.3 3.5 8.2 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF2722 PF10846.8 EGG14897.1 - 1 8.2 14.5 0.015 14.2 6.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) YecM PF06185.12 EGG14898.1 - 1.5e-47 161.5 0.2 1.8e-47 161.3 0.2 1.0 1 0 0 1 1 1 1 YecM protein GMC_oxred_C PF05199.13 EGG14899.1 - 0.0097 16.4 0.0 0.03 14.8 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DUF4326 PF14216.6 EGG14899.1 - 0.033 14.9 0.5 11 6.9 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4326) ARTD15_N PF18084.1 EGG14900.1 - 7.7e-19 67.7 0.2 3.4e-18 65.7 0.2 2.2 1 0 0 1 1 1 1 ARTD15 N-terminal domain PARP PF00644.20 EGG14900.1 - 2.4e-05 24.0 0.8 2.4e-05 24.0 0.8 2.6 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain AFG1_ATPase PF03969.16 EGG14900.1 - 0.038 12.9 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Mucin PF01456.17 EGG14900.1 - 0.93 9.5 31.1 1.2 9.1 6.6 3.6 3 0 0 3 3 3 0 Mucin-like glycoprotein Solute_trans_a PF03619.16 EGG14902.1 - 3.1e-78 262.9 32.5 4.1e-78 262.6 32.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Hexapep PF00132.24 EGG14903.1 - 8.8e-16 56.9 10.9 8.2e-06 25.3 1.9 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGG14903.1 - 2e-11 43.4 5.1 0.0045 16.7 2.7 3.8 2 1 2 4 4 4 4 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EGG14903.1 - 0.0011 17.2 0.5 0.0015 16.8 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EGG14903.1 - 0.071 12.0 0.4 0.44 9.4 0.1 2.0 1 1 1 2 2 2 0 L-fucokinase Thr_synth_N PF14821.6 EGG14904.1 - 8e-20 70.8 0.1 2.3e-18 66.2 0.0 3.0 3 0 0 3 3 3 1 Threonine synthase N terminus PALP PF00291.25 EGG14904.1 - 1.6e-15 57.3 0.0 1.5e-14 54.1 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DNA_ligase_OB PF03120.16 EGG14904.1 - 0.054 13.4 0.1 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase OB-fold domain UQ_con PF00179.26 EGG14906.1 - 8e-39 132.5 0.0 9.3e-39 132.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGG14906.1 - 0.0012 18.5 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B ADH_N PF08240.12 EGG14907.1 - 6.5e-29 100.0 6.6 1.1e-28 99.3 6.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain LLGL PF08366.13 EGG14907.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 LLGL2 ADH_zinc_N PF00107.26 EGG14908.1 - 8.9e-12 45.1 0.0 1.6e-11 44.3 0.0 1.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGG14908.1 - 0.14 13.2 0.0 0.23 12.5 0.0 1.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Peptidase_C48 PF02902.19 EGG14909.1 - 0.018 14.9 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain DKCLD PF08068.12 EGG14909.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 DKCLD (NUC011) domain CNOT1_TTP_bind PF16417.5 EGG14910.1 - 0.062 12.5 7.7 0.028 13.6 4.9 1.7 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 1 TTP binding domain LXG PF04740.12 EGG14910.1 - 0.094 12.4 13.7 0.19 11.4 13.6 1.5 1 1 1 2 2 2 0 LXG domain of WXG superfamily Prominin PF05478.11 EGG14910.1 - 0.24 9.3 7.9 0.26 9.2 7.9 1.2 1 0 0 1 1 1 0 Prominin LPD30 PF18850.1 EGG14910.1 - 0.27 11.0 3.2 0.37 10.5 2.2 1.7 2 0 0 2 2 2 0 Large polyvalent protein associated domain 30 FapA PF03961.13 EGG14910.1 - 0.38 9.3 8.7 0.5 8.9 8.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Jnk-SapK_ap_N PF09744.9 EGG14910.1 - 0.44 10.8 19.7 0.5 10.6 18.9 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Lipase_GDSL_3 PF14606.6 EGG14910.1 - 1.1 9.4 4.6 1.2 9.2 3.8 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF1043 PF06295.12 EGG14910.1 - 1.5 8.9 16.0 0.049 13.6 4.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) XhlA PF10779.9 EGG14910.1 - 3 8.1 12.8 5.4 7.3 0.0 3.5 2 1 0 2 2 2 0 Haemolysin XhlA TMPIT PF07851.13 EGG14910.1 - 3.8 6.7 7.8 4.5 6.4 7.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.15 EGG14910.1 - 4.7 6.7 11.9 5.7 6.4 11.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ACCA PF03255.14 EGG14910.1 - 5.1 7.0 10.1 0.32 10.9 3.3 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4407 PF14362.6 EGG14910.1 - 5.4 6.3 9.1 7.1 5.9 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Htr2 PF17909.1 EGG14912.1 - 0.14 12.5 0.4 0.22 11.8 0.4 1.2 1 0 0 1 1 1 0 Htr2 transmembrane domain Iso_dh PF00180.20 EGG14914.1 - 2.2e-77 260.6 0.0 2.8e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SPA PF08616.10 EGG14915.1 - 1.9e-12 47.1 0.1 4.3e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EGG14915.1 - 7.1e-12 44.7 1.0 5e-06 25.5 0.1 2.1 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.9 EGG14915.1 - 1.4e-06 28.2 0.3 7.2e-06 25.8 0.3 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Ufd2P_core PF10408.9 EGG14916.1 - 4.1e-181 603.8 16.3 4.1e-181 603.8 16.3 2.1 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.15 EGG14916.1 - 3.4e-30 104.0 1.2 9.1e-30 102.7 1.2 1.8 1 0 0 1 1 1 1 U-box domain UT PF03253.14 EGG14917.1 - 4.5e-39 134.3 23.2 5.6e-39 134.0 23.2 1.1 1 0 0 1 1 1 1 Urea transporter DUF3808 PF10300.9 EGG14918.1 - 2.9e-40 138.4 12.0 4.2e-40 137.9 10.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 EGG14918.1 - 7.6e-09 35.7 6.4 0.00064 20.0 0.4 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG14918.1 - 5.7e-07 29.2 14.3 0.068 13.3 0.1 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG14918.1 - 0.0004 20.8 4.4 0.13 12.9 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG14918.1 - 0.0021 17.8 16.5 0.29 11.0 0.1 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG14918.1 - 0.008 16.3 15.7 0.39 11.0 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGG14918.1 - 0.058 13.3 0.8 1.2 9.1 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGG14918.1 - 0.073 12.8 2.4 18 5.1 0.0 3.8 4 0 0 4 4 4 0 TPR repeat MORN_2 PF07661.13 EGG14918.1 - 0.12 12.7 0.3 5.4 7.6 0.0 2.9 2 0 0 2 2 2 0 MORN repeat variant TPR_14 PF13428.6 EGG14918.1 - 0.13 13.1 1.3 57 4.9 0.1 3.6 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG14918.1 - 2.3 8.4 9.0 0.3 11.2 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DNA_pol_B PF00136.21 EGG14919.1 - 1.5e-117 393.2 0.7 1.9e-117 392.8 0.7 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EGG14919.1 - 1.8e-22 80.0 12.4 4e-22 78.9 12.4 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger mCpol PF18182.1 EGG14919.1 - 0.023 15.0 2.0 0.61 10.4 0.5 2.6 2 0 0 2 2 2 0 minimal CRISPR polymerase domain Rhodanese_C PF12368.8 EGG14919.1 - 8.6 6.8 14.5 72 3.9 9.4 3.2 2 1 0 2 2 2 0 Rhodanase C-terminal DNA_pol_B_exo1 PF03104.19 EGG14920.1 - 9.1e-30 103.9 1.0 9.1e-30 103.9 1.0 2.2 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DUF1461 PF07314.11 EGG14921.1 - 6.3 6.7 6.3 2.8 7.8 4.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) LANC_like PF05147.13 EGG14922.1 - 2.5e-54 184.2 8.7 3.3e-54 183.8 8.7 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein MTS PF05175.14 EGG14923.1 - 3.4e-12 46.2 0.6 7.6e-08 32.1 0.0 3.0 2 1 1 3 3 3 2 Methyltransferase small domain PrmA PF06325.13 EGG14923.1 - 1.8e-08 34.2 0.1 1.8e-08 34.2 0.1 2.2 3 1 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EGG14923.1 - 7.6e-07 29.0 0.5 2e-05 24.4 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG14923.1 - 8.8e-07 29.5 0.1 4.1e-05 24.2 0.0 3.1 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG14923.1 - 8.6e-06 26.4 3.6 0.00032 21.4 0.5 3.8 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG14923.1 - 0.00016 21.5 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGG14923.1 - 0.00029 20.8 0.1 0.00093 19.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGG14923.1 - 0.00082 19.4 0.0 0.00082 19.4 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain PCMT PF01135.19 EGG14923.1 - 0.0013 18.6 0.0 0.016 15.0 0.0 2.3 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EGG14923.1 - 0.029 14.1 1.0 0.086 12.6 0.3 2.2 1 1 1 2 2 2 0 Lysine methyltransferase Methyltransf_11 PF08241.12 EGG14923.1 - 0.033 14.8 0.0 0.19 12.4 0.0 2.4 3 0 0 3 3 2 0 Methyltransferase domain UPF0020 PF01170.18 EGG14923.1 - 0.034 13.8 1.2 5.9 6.5 0.1 3.3 2 1 1 3 3 3 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 EGG14923.1 - 0.25 10.8 0.1 0.25 10.8 0.1 2.7 3 1 0 3 3 3 0 Putative methyltransferase AAA_23 PF13476.6 EGG14923.1 - 0.62 10.5 18.9 0.014 15.9 7.6 2.3 1 1 1 2 2 1 0 AAA domain LRR_6 PF13516.6 EGG14924.1 - 4.9e-47 154.0 60.2 2.8e-06 26.9 0.2 17.9 20 0 0 20 20 20 13 Leucine Rich repeat F-box-like PF12937.7 EGG14924.1 - 0.00016 21.5 0.0 0.00053 19.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 EGG14924.1 - 0.00024 21.2 41.8 5.5 7.9 0.0 14.8 16 2 0 16 16 16 1 Leucine Rich Repeat LRR_4 PF12799.7 EGG14924.1 - 0.00032 21.0 73.8 0.072 13.5 5.6 12.7 5 4 6 12 12 12 8 Leucine Rich repeats (2 copies) DUF3712 PF12505.8 EGG14924.1 - 0.00043 20.5 4.9 0.011 16.0 4.9 3.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3712) T6SS_HCP PF05638.12 EGG14924.1 - 0.23 11.8 0.1 0.23 11.8 0.1 3.8 4 3 1 5 5 5 0 Type VI secretion system effector, Hcp Telomere_reg-2 PF10193.9 EGG14925.1 - 3.7e-24 85.3 0.0 1.7e-23 83.2 0.0 2.2 1 0 0 1 1 1 1 Telomere length regulation protein Patatin PF01734.22 EGG14926.1 - 1.1e-18 68.2 0.0 1.7e-17 64.3 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1980 PF09323.10 EGG14926.1 - 1.9 8.3 3.9 15 5.5 2.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Neur_chan_memb PF02932.16 EGG14926.1 - 2 8.4 6.2 3.9 7.5 6.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Acyl-CoA_dh_1 PF00441.24 EGG14927.1 - 1.6e-46 158.2 0.0 2.9e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGG14927.1 - 3.7e-28 98.4 0.0 7.1e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGG14927.1 - 1.9e-27 95.3 0.0 7.5e-27 93.4 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGG14927.1 - 2.9e-19 69.7 0.0 6.1e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain His_Phos_1 PF00300.22 EGG14928.1 - 3.7e-24 85.5 0.0 9.5e-20 71.1 0.0 3.0 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Herpes_capsid PF06112.11 EGG14928.1 - 0.0017 18.5 5.4 0.0017 18.5 5.4 2.2 2 0 0 2 2 2 1 Gammaherpesvirus capsid protein Rrp44_CSD1 PF17216.3 EGG14928.1 - 1.2 8.8 7.3 1.4 8.7 3.5 2.8 3 0 0 3 3 3 0 Rrp44-like cold shock domain Mre11_DNA_bind PF04152.14 EGG14929.1 - 6.8e-45 153.4 0.1 6.8e-45 153.4 0.1 2.3 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EGG14929.1 - 1.6e-14 54.9 2.6 4.1e-14 53.6 2.6 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG14929.1 - 2e-06 28.1 0.0 3.4e-05 24.1 0.0 2.9 2 2 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain SOG2 PF10428.9 EGG14929.1 - 0.08 12.1 14.3 0.14 11.3 14.3 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3446 PF11928.8 EGG14929.1 - 0.61 10.4 11.9 0.25 11.7 1.8 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain GPP34 PF05719.11 EGG14930.1 - 9.4e-14 51.9 0.0 1.3e-13 51.5 0.0 1.3 1 1 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) TMEM132D_C PF15706.5 EGG14931.1 - 0.0092 15.7 0.0 0.0092 15.7 0.0 2.4 3 1 1 4 4 4 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF2615 PF11027.8 EGG14931.1 - 0.016 15.4 0.7 0.29 11.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) EphA2_TM PF14575.6 EGG14931.1 - 0.16 12.9 2.8 4.3 8.3 0.0 2.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Chordopox_A13L PF05961.11 EGG14931.1 - 0.55 10.5 0.1 0.55 10.5 0.1 2.9 2 2 1 3 3 3 0 Chordopoxvirus A13L protein Transglut_prok PF09017.10 EGG14932.1 - 0.085 12.2 0.1 0.093 12.1 0.1 1.0 1 0 0 1 1 1 0 Microbial transglutaminase SR-25 PF10500.9 EGG14933.1 - 0.071 12.7 4.4 0.1 12.2 4.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Orf78 PF06024.12 EGG14933.1 - 0.25 11.7 0.1 0.25 11.7 0.1 3.0 3 2 2 5 5 5 0 Orf78 (ac78) GWT1 PF06423.12 EGG14933.1 - 2.5 8.2 14.0 0.2 11.8 3.9 2.8 1 1 1 2 2 2 0 GWT1 Ribosomal_L6 PF00347.23 EGG14934.1 - 2.6e-19 69.7 2.1 2.1e-11 44.4 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Yae1_N PF09811.9 EGG14935.1 - 4e-09 36.0 0.5 6.3e-09 35.4 0.5 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal TIP120 PF08623.10 EGG14935.1 - 0.14 11.9 5.0 0.64 9.8 2.9 2.3 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Tetraspanin PF00335.20 EGG14935.1 - 0.45 10.2 5.4 0.67 9.6 5.4 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF4207 PF13904.6 EGG14936.1 - 0.012 15.3 2.5 0.014 15.1 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) WD40 PF00400.32 EGG14937.1 - 8e-15 55.0 12.4 3e-05 24.7 0.3 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG14937.1 - 1.6e-07 31.5 0.6 0.0053 17.0 0.0 3.6 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG14937.1 - 0.00027 20.4 0.6 0.76 9.1 0.0 3.0 2 1 1 3 3 3 2 WD40-like domain DUF4776 PF16003.5 EGG14937.1 - 0.31 10.0 26.2 0.49 9.3 26.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) PQQ_3 PF13570.6 EGG14937.1 - 0.6 10.7 4.6 4.1 8.0 0.5 3.6 5 0 0 5 5 5 0 PQQ-like domain Ins_P5_2-kin PF06090.12 EGG14938.1 - 8.3e-80 268.7 0.2 1e-79 268.4 0.2 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Tetradecapep PF08187.11 EGG14938.1 - 0.17 12.0 0.7 0.63 10.2 0.1 2.2 2 0 0 2 2 2 0 Myoactive tetradecapeptides family Ribosomal_L29 PF00831.23 EGG14939.1 - 5.9e-16 58.2 5.0 5.9e-16 58.2 5.0 1.8 2 1 0 2 2 2 1 Ribosomal L29 protein DUF3860 PF12976.7 EGG14939.1 - 0.24 11.4 3.0 3 7.9 1.0 2.1 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) Kri1 PF05178.12 EGG14939.1 - 0.6 10.7 3.3 0.91 10.1 2.6 1.8 1 1 0 1 1 1 0 KRI1-like family Nop10p PF04135.12 EGG14940.1 - 6.3e-22 77.4 0.5 7.7e-22 77.1 0.5 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family UQ_con PF00179.26 EGG14941.1 - 6.1e-23 81.0 0.1 6.1e-23 81.0 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme YL1 PF05764.13 EGG14941.1 - 0.42 10.7 31.8 1.3 9.0 31.8 1.9 1 1 0 1 1 1 0 YL1 nuclear protein PI3K_1B_p101 PF10486.9 EGG14941.1 - 0.7 7.6 14.6 1 7.1 14.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2547 PF10818.8 EGG14941.1 - 0.73 10.8 0.0 0.73 10.8 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2547) DNA_pol_phi PF04931.13 EGG14941.1 - 3.4 5.7 31.6 6.1 4.8 31.6 1.4 1 0 0 1 1 1 0 DNA polymerase phi Utp14 PF04615.13 EGG14941.1 - 4.7 5.7 28.1 6.1 5.3 28.1 1.1 1 0 0 1 1 1 0 Utp14 protein Myosin_head PF00063.21 EGG14943.1 - 3.5e-279 927.7 7.9 3.5e-279 927.7 7.9 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGG14943.1 - 5.9e-43 146.7 3.9 1.6e-42 145.4 3.9 1.7 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 EGG14943.1 - 9.8e-15 54.1 0.0 6.1e-14 51.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EGG14943.1 - 8e-14 51.0 0.0 1.6e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG14943.1 - 1.9e-08 33.8 0.0 4.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 EGG14943.1 - 0.0015 19.0 0.0 0.0043 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Hpr_kinase_C PF07475.12 EGG14943.1 - 0.023 14.2 0.3 0.78 9.2 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.27 EGG14943.1 - 0.067 13.7 0.0 0.22 12.1 0.0 2.0 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EGG14943.1 - 0.08 12.2 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin INTS5_N PF14837.6 EGG14943.1 - 0.12 11.9 0.0 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus AAA_22 PF13401.6 EGG14943.1 - 0.13 12.6 0.0 0.46 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGG14943.1 - 0.13 12.8 0.0 0.43 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain DSPc PF00782.20 EGG14944.1 - 2.4e-30 105.0 0.1 2e-29 102.1 0.0 2.6 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 EGG14944.1 - 3.2e-16 58.8 27.3 4.1e-09 36.1 2.7 5.1 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 EGG14944.1 - 5.6e-11 42.5 33.1 0.00014 22.1 1.5 5.5 3 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGG14944.1 - 1.4e-05 24.7 9.4 0.0014 18.1 0.6 3.4 1 1 3 4 4 4 4 Leucine-rich repeat Y_phosphatase PF00102.27 EGG14944.1 - 0.0054 16.3 0.4 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DUF3449 PF11931.8 EGG14944.1 - 3.5 7.4 7.2 0.37 10.6 1.8 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3449) PS_Dcarbxylase PF02666.15 EGG14945.1 - 2.5e-55 187.2 0.0 4.2e-55 186.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EGG14945.1 - 1.8e-27 95.6 0.3 4.9e-27 94.2 0.1 1.9 2 0 0 2 2 2 1 C2 domain EF-hand_7 PF13499.6 EGG14945.1 - 2.5e-05 24.6 0.2 0.0001 22.7 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGG14945.1 - 5.3e-05 22.5 0.3 0.00017 20.9 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EGG14945.1 - 0.0019 17.6 0.1 0.0065 15.9 0.1 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGG14945.1 - 0.002 17.9 0.1 0.0077 16.1 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain YccV-like PF08755.11 EGG14945.1 - 0.0089 16.5 1.1 0.09 13.3 1.8 2.3 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like EF-hand_8 PF13833.6 EGG14945.1 - 0.013 15.3 0.2 0.044 13.6 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain pair Swm2 PF17083.5 EGG14945.1 - 0.98 9.4 6.1 6.9 6.7 4.2 2.7 2 0 0 2 2 2 0 Nucleolar protein Swm2 RCC1_2 PF13540.6 EGG14946.1 - 1.5e-40 136.2 15.1 2.7e-10 39.8 0.0 6.8 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RhoGAP PF00620.27 EGG14946.1 - 5.1e-33 114.1 0.5 5.1e-33 114.1 0.5 1.9 2 0 0 2 2 2 1 RhoGAP domain RCC1 PF00415.18 EGG14946.1 - 9.4e-28 96.6 28.8 1.1e-08 35.6 0.0 10.2 9 2 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 EGG14946.1 - 0.11 12.2 11.1 4 7.1 0.0 5.6 6 1 1 7 7 7 0 TUP1-like enhancer of split DUF1459 PF07312.11 EGG14946.1 - 0.13 12.4 0.6 52 4.1 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1459) IFT20 PF14931.6 EGG14946.1 - 3.7 7.7 13.2 4.8 7.4 0.9 3.6 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 Myosin_head PF00063.21 EGG14947.1 - 1.2e-175 585.6 34.8 1.2e-175 585.6 34.8 2.3 2 0 0 2 2 2 1 Myosin head (motor domain) RhoGEF PF00621.20 EGG14947.1 - 4.1e-50 170.5 4.4 4.1e-50 170.5 4.4 5.9 6 2 2 8 8 8 1 RhoGEF domain PH PF00169.29 EGG14947.1 - 1.1e-05 25.9 0.1 7.1e-05 23.3 0.1 2.5 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 EGG14947.1 - 4.8e-05 23.6 0.0 4.8e-05 23.6 0.0 6.1 5 1 0 5 5 5 1 Pleckstrin homology domain AAA_22 PF13401.6 EGG14947.1 - 0.0076 16.5 0.1 0.089 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 EGG14947.1 - 0.56 9.9 5.0 0.098 12.4 0.5 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Pkinase PF00069.25 EGG14948.1 - 9.8e-32 110.3 0.2 2.3e-31 109.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain EF-hand_7 PF13499.6 EGG14948.1 - 1.9e-21 76.3 6.7 6.5e-06 26.5 0.4 4.8 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 EGG14948.1 - 1.2e-20 71.4 14.0 0.00016 21.0 0.3 6.0 5 0 0 5 5 5 4 EF hand Pkinase_Tyr PF07714.17 EGG14948.1 - 7.3e-20 71.3 0.0 2e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_6 PF13405.6 EGG14948.1 - 2.3e-17 61.4 14.5 0.017 15.0 0.1 6.8 5 1 1 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 EGG14948.1 - 1.6e-10 40.0 10.2 0.00068 19.0 0.4 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGG14948.1 - 3.4e-10 39.6 7.1 0.023 14.5 0.1 4.8 4 0 0 4 4 4 3 EF-hand domain pair Pkinase_fungal PF17667.1 EGG14948.1 - 0.0001 21.3 0.0 0.0001 21.3 0.0 2.7 2 1 0 2 2 1 1 Fungal protein kinase APH PF01636.23 EGG14948.1 - 0.0018 18.2 0.0 0.025 14.5 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family EF-hand_4 PF12763.7 EGG14948.1 - 0.0045 16.9 3.7 6.7 6.7 0.1 4.0 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EGG14948.1 - 0.0072 16.5 0.5 0.23 11.7 0.3 3.3 2 1 1 3 3 3 1 Dockerin type I domain DUF5522 PF17653.1 EGG14948.1 - 0.18 11.8 2.0 0.52 10.3 2.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5522) SPARC_Ca_bdg PF10591.9 EGG14948.1 - 0.68 10.3 0.0 0.68 10.3 0.0 4.4 4 2 1 5 5 5 0 Secreted protein acidic and rich in cysteine Ca binding region Prefoldin_2 PF01920.20 EGG14949.1 - 3.1e-13 49.6 7.7 4e-13 49.2 7.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit SesA PF17107.5 EGG14949.1 - 0.0021 18.2 0.6 0.0031 17.7 0.6 1.2 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TMA7 PF09072.10 EGG14949.1 - 2.5 9.0 7.9 8.3 7.3 7.9 2.0 1 1 0 1 1 1 0 Translation machinery associated TMA7 PIP5K PF01504.18 EGG14950.1 - 1e-34 120.1 0.8 6.8e-32 110.8 0.2 5.2 2 2 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EGG14950.1 - 1e-20 73.9 0.1 2.5e-19 69.3 0.1 2.2 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EGG14950.1 - 1.2e-15 57.4 14.1 1.2e-15 57.4 14.1 2.1 2 0 0 2 2 2 1 FYVE zinc finger DUF2448 PF10476.9 EGG14951.1 - 0.73 9.7 0.0 0.73 9.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function C-terminus (DUF2448) Pex2_Pex12 PF04757.14 EGG14951.1 - 0.8 9.2 12.0 0.11 12.1 0.5 2.6 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region CENP-B_dimeris PF09026.10 EGG14951.1 - 1.5 9.3 30.6 1.5 9.3 0.1 4.6 4 0 0 4 4 4 0 Centromere protein B dimerisation domain GRAM PF02893.20 EGG14952.1 - 1e-06 28.6 0.2 6e-05 22.9 0.1 3.3 2 0 0 2 2 2 1 GRAM domain C2 PF00168.30 EGG14952.1 - 5e-05 23.5 0.0 0.00039 20.7 0.0 2.6 2 0 0 2 2 2 1 C2 domain Membr_traf_MHD PF10540.9 EGG14952.1 - 0.0005 20.3 0.0 0.088 13.0 0.0 3.9 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain ubiquitin PF00240.23 EGG14952.1 - 0.11 12.3 1.2 2.2 8.1 0.0 3.8 3 0 0 3 3 3 0 Ubiquitin family PCMT PF01135.19 EGG14953.1 - 6.7e-33 114.2 0.0 1e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGG14953.1 - 5.4e-10 39.3 0.0 1.6e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG14953.1 - 6.9e-08 33.1 0.0 2.6e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain BTB PF00651.31 EGG14953.1 - 8.4e-07 29.2 5.5 0.0033 17.6 0.2 4.0 3 1 1 4 4 4 2 BTB/POZ domain BACK PF07707.15 EGG14953.1 - 1.1e-05 25.5 0.3 3.7e-05 23.8 0.3 2.0 1 0 0 1 1 1 1 BTB And C-terminal Kelch Methyltransf_23 PF13489.6 EGG14953.1 - 0.00019 21.3 0.0 0.00052 19.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG14953.1 - 0.00028 20.3 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EGG14953.1 - 0.00031 20.2 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGG14953.1 - 0.001 19.7 0.0 0.0037 17.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.10 EGG14953.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 EGG14953.1 - 0.0022 17.5 0.1 0.0087 15.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGG14953.1 - 0.0091 16.7 0.2 0.044 14.5 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 EGG14953.1 - 0.015 14.6 0.0 0.035 13.4 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 EGG14953.1 - 0.044 13.8 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 EGG14953.1 - 0.047 13.1 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa PH_3 PF14593.6 EGG14954.1 - 2.1e-15 56.7 0.1 1.1e-14 54.4 0.1 2.4 1 1 0 1 1 1 1 PH domain PH PF00169.29 EGG14954.1 - 8.7e-07 29.4 0.1 8.7e-07 29.4 0.1 3.5 3 1 1 4 4 4 1 PH domain PH_8 PF15409.6 EGG14954.1 - 0.0024 18.1 0.1 0.0079 16.5 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain EMP24_GP25L PF01105.24 EGG14955.1 - 5.5e-50 169.8 0.3 6.8e-50 169.5 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 EGG14955.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 SdrD B-like domain ATP_bind_3 PF01171.20 EGG14956.1 - 1.5e-22 80.3 0.1 1.5e-22 80.3 0.1 3.5 2 1 0 2 2 2 1 PP-loop family TFIIA PF03153.13 EGG14956.1 - 9.9e-05 22.5 37.1 9.9e-05 22.5 37.1 2.5 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit PepSY_TM PF03929.16 EGG14956.1 - 1.1 8.9 2.7 1.8 8.2 2.7 1.4 1 0 0 1 1 1 0 PepSY-associated TM region Rcd1 PF04078.13 EGG14957.1 - 1.5e-70 237.5 5.9 2e-70 237.1 5.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Guanylate_cyc PF00211.20 EGG14958.1 - 4.9e-104 345.7 6.3 3.3e-54 183.3 0.2 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Ada3 PF10198.9 EGG14959.1 - 8.8e-12 45.3 10.0 8.8e-12 45.3 10.0 3.0 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 FmiP_Thoc5 PF09766.9 EGG14960.1 - 3.3e-74 250.4 26.5 3.3e-74 250.4 26.5 2.2 3 0 0 3 3 3 1 Fms-interacting protein/Thoc5 DUF2722 PF10846.8 EGG14960.1 - 6.2e-06 25.4 8.6 6.2e-06 25.4 8.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) ANAPC_CDC26 PF10471.9 EGG14960.1 - 0.027 15.3 13.2 0.027 15.3 13.2 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 FHIPEP PF00771.20 EGG14960.1 - 0.27 9.6 10.5 0.031 12.7 2.7 2.3 2 0 0 2 2 2 0 FHIPEP family CagX PF03524.15 EGG14960.1 - 0.81 9.4 9.0 0.062 13.0 2.4 2.2 2 0 0 2 2 2 0 Conjugal transfer protein Pex14_N PF04695.13 EGG14960.1 - 2.6 8.7 16.1 0.59 10.8 9.6 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EIIBC-GUT_N PF03612.14 EGG14960.1 - 4.7 6.9 11.6 3.1 7.5 3.4 2.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Rxt3 PF08642.10 EGG14960.1 - 5.8 7.7 7.5 2.1 9.1 0.9 2.8 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF4820 PF16091.5 EGG14960.1 - 6.6 6.0 14.7 0.031 13.6 2.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4820) Bystin PF05291.11 EGG14961.1 - 5.9e-117 390.1 5.2 5.9e-117 390.1 5.2 1.5 2 0 0 2 2 2 1 Bystin Ras PF00071.22 EGG14962.1 - 3.3e-57 192.6 0.0 3.9e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG14962.1 - 6.8e-23 81.2 0.0 1.3e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG14962.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family ABC_membrane PF00664.23 EGG14964.1 - 2.8e-46 158.4 26.9 2.8e-46 158.4 26.9 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region Peptidase_S8 PF00082.22 EGG14964.1 - 2.6e-43 148.4 4.3 2.6e-43 148.4 4.3 2.6 3 0 0 3 3 3 1 Subtilase family ABC_tran PF00005.27 EGG14964.1 - 9.3e-31 107.2 0.0 2.9e-30 105.6 0.0 2.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGG14964.1 - 2.5e-08 33.6 0.0 2.8e-06 26.9 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGG14964.1 - 0.00038 20.4 0.1 0.89 9.3 0.0 2.6 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGG14964.1 - 0.0052 17.1 0.0 0.017 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain FAM176 PF14851.6 EGG14964.1 - 0.037 13.7 2.0 0.084 12.5 0.9 2.0 2 0 0 2 2 2 0 FAM176 family AAA_29 PF13555.6 EGG14964.1 - 0.052 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG14964.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase CDC45 PF02724.14 EGG14964.1 - 0.34 9.2 3.2 0.52 8.5 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein PPC PF04151.15 EGG14964.1 - 2.1 9.5 5.1 2.5 9.3 0.2 3.1 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain UCR_14kD PF02271.16 EGG14965.1 - 3.1e-17 62.4 0.8 3.3e-17 62.3 0.8 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit TIP49 PF06068.13 EGG14966.1 - 3.3e-168 559.3 0.9 4.3e-168 559.0 0.9 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGG14966.1 - 7e-24 83.7 0.2 2.8e-23 81.8 0.1 2.1 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EGG14966.1 - 8.7e-12 45.6 0.1 2e-07 31.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGG14966.1 - 1e-10 41.6 0.2 1.1e-06 28.5 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGG14966.1 - 7.7e-07 29.5 1.1 0.029 14.6 0.0 3.1 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EGG14966.1 - 1.7e-05 24.8 0.1 0.0032 17.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGG14966.1 - 5e-05 23.7 0.1 0.003 17.9 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 EGG14966.1 - 5e-05 22.9 0.1 0.00017 21.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGG14966.1 - 0.00029 20.3 0.3 0.02 14.3 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGG14966.1 - 0.0011 19.0 0.0 0.44 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGG14966.1 - 0.0027 17.5 0.1 0.0054 16.5 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DnaB_C PF03796.15 EGG14966.1 - 0.0027 17.1 0.0 0.007 15.7 0.0 1.7 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 EGG14966.1 - 0.0042 16.8 0.1 1.7 8.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 EGG14966.1 - 0.012 15.9 4.3 0.42 10.9 4.3 2.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGG14966.1 - 0.016 15.4 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGG14966.1 - 0.036 14.1 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EGG14966.1 - 0.039 14.5 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGG14966.1 - 0.051 13.4 2.0 0.056 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EGG14966.1 - 0.053 12.6 0.1 0.11 11.5 0.1 1.5 1 1 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 EGG14966.1 - 0.063 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 EGG14966.1 - 0.082 12.2 0.2 0.18 11.1 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 EGG14966.1 - 0.082 12.3 0.2 0.082 12.3 0.2 2.0 3 0 0 3 3 1 0 PhoH-like protein ResIII PF04851.15 EGG14966.1 - 0.094 12.7 0.6 1.5 8.8 0.1 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 EGG14966.1 - 0.1 13.0 0.0 0.36 11.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 EGG14966.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 EGG14966.1 - 0.24 10.9 0.0 0.24 10.9 0.0 2.4 3 0 0 3 3 2 0 P-loop containing dynein motor region Pyridoxal_deC PF00282.19 EGG14967.1 - 1.7e-16 59.9 0.0 6.1e-12 44.9 0.0 3.1 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Pyridoxal_deC PF00282.19 EGG14968.1 - 1.1e-19 70.4 0.2 6.7e-11 41.5 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain P16-Arc PF04699.14 EGG14969.1 - 1.9e-33 116.1 0.0 2e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp13 PF08625.11 EGG14969.1 - 0.15 11.9 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Utp12 PF04003.12 EGG14969.1 - 0.17 12.2 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 Dip2/Utp12 Family Aminotran_3 PF00202.21 EGG14970.1 - 7.2e-100 334.5 0.0 8.9e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGG14970.1 - 0.002 17.4 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGG14970.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase DBP10CT PF08147.12 EGG14971.1 - 0.022 15.0 0.5 0.029 14.6 0.5 1.2 1 0 0 1 1 1 0 DBP10CT (NUC160) domain ubiquitin PF00240.23 EGG14972.1 - 0.0045 16.7 0.2 0.0098 15.6 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family GTSE1_N PF15259.6 EGG14972.1 - 2.1 8.5 7.9 0.27 11.4 1.0 2.5 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 Apis_Csd PF11671.8 EGG14972.1 - 2.6 8.1 14.2 1.6 8.7 3.3 2.7 2 0 0 2 2 2 0 Complementary sex determiner protein RNR_Alpha PF17975.1 EGG14973.1 - 1.1e-44 151.0 1.1 5.2e-44 148.8 0.2 2.6 3 0 0 3 3 3 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 EGG14973.1 - 3.6e-08 32.4 0.0 0.0032 16.1 0.0 3.3 3 0 0 3 3 3 2 Ribonucleotide reductase, barrel domain Beta_helix PF13229.6 EGG14974.1 - 2.2e-42 144.6 62.5 2.9e-23 82.4 25.6 3.8 2 1 2 4 4 4 3 Right handed beta helix region NosD PF05048.13 EGG14974.1 - 5.5e-25 88.0 55.6 2.6e-12 46.5 15.0 4.5 3 1 2 5 5 5 3 Periplasmic copper-binding protein (NosD) zf-UBR PF02207.20 EGG14974.1 - 1.3e-07 31.6 13.3 1.3e-07 31.6 13.3 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) F-box-like PF12937.7 EGG14974.1 - 3.4e-07 30.0 0.6 7.1e-07 29.0 0.6 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG14974.1 - 8.7e-05 22.3 0.5 0.00018 21.3 0.5 1.5 1 0 0 1 1 1 1 F-box domain Pectinesterase PF01095.19 EGG14974.1 - 0.00092 18.0 0.1 0.0024 16.6 0.1 1.7 1 1 0 1 1 1 1 Pectinesterase Peptidase_M41 PF01434.18 EGG14975.1 - 1.8e-53 181.3 3.5 8.4e-53 179.1 3.5 2.0 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGG14975.1 - 1.2e-40 139.0 0.0 3.3e-40 137.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG14975.1 - 1.7e-07 30.9 0.0 3.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGG14975.1 - 6e-07 30.0 0.6 0.0014 19.1 0.1 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EGG14975.1 - 1.3e-05 25.2 0.1 9e-05 22.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGG14975.1 - 6.6e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGG14975.1 - 0.00065 19.0 0.0 0.0018 17.6 0.0 1.7 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EGG14975.1 - 0.0016 18.7 0.6 0.12 12.6 0.0 3.2 2 1 1 3 3 3 1 AAA domain TsaE PF02367.17 EGG14975.1 - 0.0077 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EGG14975.1 - 0.011 15.1 0.1 0.071 12.4 0.0 2.3 2 1 0 2 2 2 0 KaiC AAA_18 PF13238.6 EGG14975.1 - 0.02 15.4 0.0 0.088 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGG14975.1 - 0.026 14.2 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 EGG14975.1 - 0.031 14.3 0.2 0.37 10.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EGG14975.1 - 0.034 13.9 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 EGG14975.1 - 0.057 13.3 0.1 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 EGG14975.1 - 0.13 11.6 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGG14975.1 - 0.2 11.9 0.5 1.4 9.1 0.1 2.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EGG14975.1 - 0.23 12.0 2.1 3.4 8.2 0.0 3.1 3 0 0 3 3 3 0 ABC transporter TraB PF01963.17 EGG14976.1 - 1.2e-09 38.5 0.1 8.1e-09 35.8 0.1 2.0 1 1 0 1 1 1 1 TraB family AAA_22 PF13401.6 EGG14976.1 - 0.029 14.6 0.3 0.19 12.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain Gly_acyl_tr_C PF08444.10 EGG14976.1 - 0.064 13.5 0.0 0.43 10.8 0.1 2.2 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region RT_RNaseH PF17917.1 EGG14977.1 - 2e-32 111.6 0.0 5.4e-32 110.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EGG14977.1 - 5.9e-30 103.3 0.0 1.9e-29 101.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EGG14977.1 - 5e-29 101.4 0.1 1.1e-28 100.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EGG14977.1 - 6.6e-16 58.2 0.3 1.8e-15 56.8 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EGG14977.1 - 8.1e-14 51.8 0.0 3.4e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 EGG14977.1 - 7.9e-11 41.7 0.8 3e-10 39.8 0.8 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EGG14977.1 - 0.0027 17.9 0.0 0.0081 16.4 0.0 1.9 1 0 0 1 1 1 1 H2C2 zinc finger TolA_bind_tri PF16331.5 EGG14977.1 - 0.0041 17.2 2.2 0.013 15.5 2.2 1.8 1 0 0 1 1 1 1 TolA binding protein trimerisation DUF4335 PF14233.6 EGG14977.1 - 0.015 15.2 0.3 0.036 14.0 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) DUF3437 PF11919.8 EGG14977.1 - 0.029 14.3 0.2 0.1 12.5 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) CdiA_C_tRNase PF18664.1 EGG14977.1 - 0.036 14.2 0.4 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain DUF1758 PF05585.12 EGG14977.1 - 0.052 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Putative peptidase (DUF1758) CPSF100_C PF13299.6 EGG14977.1 - 0.054 13.7 0.7 0.16 12.1 0.7 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal WRKY PF03106.15 EGG14978.1 - 1.4e-12 47.6 0.6 6.8e-12 45.4 0.6 2.3 1 0 0 1 1 1 1 WRKY DNA -binding domain CMAS PF02353.20 EGG14979.1 - 3.3e-80 269.3 0.2 4e-80 269.0 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGG14979.1 - 1.1e-15 58.1 0.0 2.1e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG14979.1 - 1.3e-13 51.3 0.0 2.8e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG14979.1 - 2.6e-12 46.8 0.0 4.3e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG14979.1 - 5.2e-09 36.1 0.0 7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG14979.1 - 5.4e-08 33.5 0.8 1.8e-07 31.8 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 EGG14979.1 - 3.8e-05 23.3 0.0 7.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EGG14979.1 - 4.4e-05 23.3 0.0 0.0001 22.1 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EGG14979.1 - 0.0018 18.4 0.0 0.046 13.8 0.0 2.2 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EGG14979.1 - 0.0027 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EGG14979.1 - 0.012 15.3 0.3 0.053 13.1 0.0 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DOT1 PF08123.13 EGG14979.1 - 0.016 14.8 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_18 PF12847.7 EGG14979.1 - 0.031 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EGG14979.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DCP2 PF05026.13 EGG14980.1 - 4.9e-29 100.5 1.9 4.9e-29 100.5 1.9 2.4 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 EGG14980.1 - 3.1e-12 46.7 0.0 7.2e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain SLATT_6 PF18169.1 EGG14980.1 - 1.3 8.6 6.3 0.12 12.0 0.9 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 V-SNARE_C PF12352.8 EGG14982.1 - 6.6e-08 32.7 4.9 1e-07 32.1 3.1 2.3 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EGG14982.1 - 0.00062 19.6 0.9 0.00062 19.6 0.9 2.9 2 2 1 3 3 3 1 Sec20 DUF4407 PF14362.6 EGG14982.1 - 0.0017 17.8 3.5 0.0026 17.2 3.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) V-SNARE PF05008.15 EGG14982.1 - 0.0026 18.1 4.4 0.0026 18.1 4.4 2.4 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Mucin PF01456.17 EGG14982.1 - 0.0031 17.5 11.7 0.0051 16.8 11.7 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF812 PF05667.11 EGG14982.1 - 0.0073 15.2 3.2 0.0073 15.2 3.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF812) SSP160 PF06933.11 EGG14982.1 - 0.0081 14.4 11.1 0.011 13.9 11.1 1.3 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 WXG100 PF06013.12 EGG14982.1 - 0.049 13.9 0.3 0.049 13.9 0.3 3.3 2 2 1 3 3 3 0 Proteins of 100 residues with WXG Plasmid_RAQPRD PF09686.10 EGG14982.1 - 0.054 13.7 6.9 9.9 6.5 0.1 3.3 3 0 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF4834 PF16118.5 EGG14982.1 - 0.056 14.4 0.0 0.056 14.4 0.0 3.0 2 1 0 2 2 1 0 Domain of unknown function (DUF4834) BSMAP PF12280.8 EGG14982.1 - 0.065 13.4 0.4 0.11 12.7 0.4 1.6 1 1 0 1 1 1 0 Brain specific membrane anchored protein DUF4795 PF16043.5 EGG14982.1 - 0.18 11.4 7.9 0.24 11.0 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Rx_N PF18052.1 EGG14982.1 - 0.22 11.8 2.5 9 6.7 0.1 2.7 1 1 2 3 3 3 0 Rx N-terminal domain Type_III_YscX PF09474.10 EGG14982.1 - 0.35 11.2 3.1 3.7 7.9 0.7 2.3 1 1 1 2 2 2 0 Type III secretion system YscX (type_III_YscX) ODV-E18 PF10717.9 EGG14982.1 - 0.42 10.5 9.6 0.54 10.2 7.9 2.0 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 GP41 PF00517.17 EGG14982.1 - 0.45 10.4 4.2 0.44 10.4 0.1 2.1 2 0 0 2 2 2 0 Retroviral envelope protein ALMT PF11744.8 EGG14982.1 - 0.78 8.5 5.8 1.2 7.9 5.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter THOC7 PF05615.13 EGG14982.1 - 1.7 8.9 12.9 0.047 14.0 3.6 2.3 2 1 0 2 2 2 0 Tho complex subunit 7 Exonuc_VII_L PF02601.15 EGG14982.1 - 1.8 8.1 13.0 4.3 6.8 12.4 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 EGG14982.1 - 3.3 8.3 12.7 4.8 7.7 6.8 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Allexi_40kDa PF05549.11 EGG14982.1 - 6.3 6.2 7.4 6.5 6.2 2.2 2.3 1 1 2 3 3 3 0 Allexivirus 40kDa protein LAMTOR5 PF16672.5 EGG14983.1 - 1.3e-25 89.1 0.7 1.4e-25 89.0 0.7 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 EGG14983.1 - 0.0039 16.9 0.1 0.021 14.6 0.1 1.9 1 1 0 1 1 1 1 Roadblock/LC7 domain A_amylase_inhib PF01356.19 EGG14983.1 - 0.019 14.9 0.2 0.023 14.7 0.2 1.3 1 0 0 1 1 1 0 Alpha amylase inhibitor Ham1p_like PF01725.16 EGG14983.1 - 0.1 12.5 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Ham1 family Adaptin_N PF01602.20 EGG14984.1 - 2.5e-81 273.8 10.0 3.9e-81 273.2 10.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGG14984.1 - 4.2e-09 36.7 0.3 5.5e-08 33.0 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Coatomer_b_Cpla PF14806.6 EGG14984.1 - 0.00084 19.3 0.0 0.0036 17.3 0.0 2.1 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform HEAT PF02985.22 EGG14984.1 - 0.0042 17.2 1.1 0.12 12.7 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 EGG14984.1 - 0.006 16.9 0.2 0.066 13.6 0.1 2.7 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 EGG14984.1 - 0.012 16.1 1.0 3.6 8.2 0.2 3.6 3 1 0 3 3 3 0 HEAT-like repeat DUF3730 PF12530.8 EGG14984.1 - 0.058 13.0 7.5 1.6 8.3 0.5 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF3730) AP4E_app_platf PF14807.6 EGG14984.1 - 0.062 13.7 0.3 0.45 10.9 0.3 2.4 1 1 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DnaJ_C PF01556.18 EGG14985.1 - 7.1e-40 136.5 1.4 9.4e-40 136.1 1.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGG14985.1 - 4.3e-26 90.8 1.1 7.8e-26 90.0 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGG14985.1 - 2.2e-15 56.8 17.4 4.2e-15 55.9 17.4 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EGG14985.1 - 0.0033 17.4 7.3 0.69 9.9 0.2 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 EGG14985.1 - 0.055 13.4 15.9 0.68 9.9 4.0 2.9 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2614 PF11023.8 EGG14985.1 - 3.6 7.7 6.1 4.6 7.4 0.6 2.3 1 1 1 2 2 2 0 Zinc-ribbon containing domain YonK PF09642.10 EGG14986.1 - 0.89 9.8 2.7 2.1 8.5 0.1 2.9 4 0 0 4 4 4 0 YonK protein LRR_9 PF14580.6 EGG14987.1 - 4.3e-10 39.4 0.1 4.3e-10 39.4 0.1 2.1 2 1 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EGG14987.1 - 8.7e-06 26.0 4.7 0.00034 20.9 0.7 3.2 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG14987.1 - 0.00013 21.6 1.7 0.0095 15.7 0.1 2.8 2 1 0 2 2 2 1 Leucine rich repeat BUD22 PF09073.10 EGG14987.1 - 1.2 8.4 53.3 0.8 9.0 20.6 2.2 2 0 0 2 2 2 0 BUD22 GAGA_bind PF06217.12 EGG14987.1 - 1.3 9.2 9.3 0.22 11.7 5.6 1.7 2 0 0 2 2 2 0 GAGA binding protein-like family SDA1 PF05285.12 EGG14987.1 - 2.4 7.5 50.1 2.2 7.6 20.0 2.5 2 0 0 2 2 2 0 SDA1 Metallophos PF00149.28 EGG14988.1 - 2.3e-14 54.4 0.7 3.2e-14 53.9 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG14988.1 - 1.7e-06 28.3 0.0 0.011 15.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Choline_transpo PF04515.12 EGG14989.1 - 1.6e-63 214.9 41.9 1.6e-63 214.9 41.9 2.5 1 1 1 2 2 2 1 Plasma-membrane choline transporter DUF4291 PF14124.6 EGG14990.1 - 8.2e-68 227.8 5.5 9.4e-68 227.6 5.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Syd PF07348.12 EGG14990.1 - 0.032 13.9 0.1 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 Syd protein (SUKH-2) KH_2 PF07650.17 EGG14990.1 - 0.084 12.7 0.5 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 KH domain RRM_1 PF00076.22 EGG14992.1 - 9.7e-38 127.8 0.6 1.3e-15 56.9 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EGG14992.1 - 7.5e-10 39.8 8.9 3.5e-09 37.6 3.3 2.9 2 1 1 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 EGG14992.1 - 1.9e-06 27.6 0.0 0.0025 17.6 0.0 3.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EGG14992.1 - 5.8e-06 25.9 0.2 0.00034 20.2 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 EGG14992.1 - 2.4e-05 24.2 0.0 0.1 12.4 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1866) Limkain-b1 PF11608.8 EGG14992.1 - 0.00019 21.4 0.0 0.19 11.8 0.0 3.0 3 0 0 3 3 3 2 Limkain b1 Nup35_RRM_2 PF14605.6 EGG14992.1 - 0.0013 18.7 2.0 3.4 7.8 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif CCDC106 PF15794.5 EGG14992.1 - 0.85 9.3 6.4 18 5.0 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Dsh_C PF12316.8 EGG14992.1 - 9.2 6.6 12.1 7.6 6.9 3.7 2.5 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal MFS_1 PF07690.16 EGG14994.1 - 1.7e-39 135.7 15.6 1.7e-39 135.7 15.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG14994.1 - 9.8e-08 31.3 20.1 1.4e-06 27.5 20.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EGG14994.1 - 9.2e-06 25.2 0.1 9.2e-06 25.2 0.1 2.5 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Folate_carrier PF01770.18 EGG14994.1 - 0.038 12.7 0.0 0.038 12.7 0.0 2.1 3 0 0 3 3 3 0 Reduced folate carrier MFS_3 PF05977.13 EGG14994.1 - 0.065 11.6 7.6 0.068 11.5 0.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector PrmA PF06325.13 EGG14995.1 - 2.8e-08 33.5 0.0 5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGG14995.1 - 7.1e-08 33.0 0.1 3.3e-07 30.8 0.0 2.2 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG14995.1 - 1.2e-07 32.4 0.0 4.6e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGG14995.1 - 8e-06 25.5 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.16 EGG14995.1 - 2.6e-05 24.1 0.0 4.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase TehB PF03848.14 EGG14995.1 - 4e-05 23.1 1.0 9.4e-05 21.9 0.1 1.9 1 1 1 2 2 2 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 EGG14995.1 - 6.6e-05 22.8 0.0 0.00015 21.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG14995.1 - 0.00031 21.4 0.0 0.0049 17.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGG14995.1 - 0.0004 20.3 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGG14995.1 - 0.0087 15.8 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGG14995.1 - 0.022 14.5 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.11 EGG14995.1 - 0.068 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 EGG14995.1 - 0.071 13.1 0.4 0.7 9.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Pex2_Pex12 PF04757.14 EGG14996.1 - 3e-32 112.0 12.5 9.3e-32 110.4 12.5 1.8 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EGG14996.1 - 4.3e-09 36.1 9.6 6.7e-09 35.5 9.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG14996.1 - 5.4e-08 33.0 13.8 9e-08 32.3 13.8 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EGG14996.1 - 3.9e-06 26.6 9.6 6.6e-06 25.9 9.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGG14996.1 - 6.3e-06 25.9 13.8 1.1e-05 25.1 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG14996.1 - 9.6e-06 25.4 14.5 1.8e-05 24.5 14.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGG14996.1 - 1.5e-05 25.1 9.4 3.3e-05 24.1 9.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGG14996.1 - 0.009 16.0 9.0 0.0096 15.9 6.7 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG14996.1 - 0.013 15.4 11.9 0.026 14.5 11.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGG14996.1 - 0.09 13.0 12.3 0.17 12.1 12.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGG14996.1 - 0.29 11.2 5.4 0.74 9.9 5.4 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGG14996.1 - 0.48 10.3 9.9 0.94 9.3 9.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Got1 PF04178.12 EGG14997.1 - 1.8e-13 50.9 16.5 2.2e-13 50.6 16.5 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF202 PF02656.15 EGG14997.1 - 0.064 13.7 7.2 0.53 10.8 1.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF202) zf-DNL PF05180.12 EGG14998.1 - 3.8e-27 94.0 0.4 7.4e-27 93.1 0.4 1.4 1 0 0 1 1 1 1 DNL zinc finger RRM_1 PF00076.22 EGG14999.1 - 4.3e-57 189.8 0.4 5.3e-19 67.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG14999.1 - 1.9e-10 40.4 1.2 0.0026 17.4 0.2 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG14999.1 - 4.5e-06 26.4 0.1 0.0013 18.5 0.0 3.3 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EGG14999.1 - 0.004 17.2 3.9 1.5 9.0 0.0 3.7 4 1 0 4 4 4 2 RNA recognition motif RRM_3 PF08777.11 EGG14999.1 - 0.0044 17.0 0.0 0.19 11.8 0.0 3.7 3 1 0 3 3 3 2 RNA binding motif BRAP2 PF07576.12 EGG14999.1 - 0.012 15.9 0.1 0.48 10.7 0.0 2.5 2 0 0 2 2 2 0 BRCA1-associated protein 2 Limkain-b1 PF11608.8 EGG14999.1 - 0.029 14.4 4.1 0.68 10.1 0.0 3.5 4 0 0 4 4 4 0 Limkain b1 Asparaginase_2 PF01112.18 EGG14999.1 - 0.082 11.9 2.9 0.17 10.9 2.9 1.4 1 0 0 1 1 1 0 Asparaginase DUF2367 PF10164.9 EGG14999.1 - 9.6 6.8 8.2 4.1e+02 1.5 8.7 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) CBM49 PF09478.10 EGG15000.1 - 6.1e-06 26.5 1.5 9.8e-06 25.8 1.1 1.5 1 1 0 1 1 1 1 Carbohydrate binding domain CBM49 MBG PF17883.1 EGG15000.1 - 0.013 16.0 1.4 0.027 15.1 1.3 1.6 1 1 1 2 2 2 0 MBG domain CBM_2 PF00553.19 EGG15000.1 - 0.019 15.2 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Cellulose binding domain Curto_V3 PF07436.11 EGG15000.1 - 0.38 11.2 0.2 0.38 11.2 0.2 1.7 2 0 0 2 2 2 0 Curtovirus V3 protein Ank_2 PF12796.7 EGG15002.1 - 8e-05 23.1 0.3 0.011 16.2 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG15002.1 - 0.0069 16.8 0.2 51 4.9 0.0 4.7 3 2 2 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EGG15002.1 - 0.049 14.2 0.1 11 6.7 0.0 3.8 2 2 1 3 3 3 0 Ankyrin repeats (many copies) UQ_con PF00179.26 EGG15003.1 - 1.2e-38 132.0 0.0 2.2e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGG15003.1 - 0.0022 17.9 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 EGG15003.1 - 0.029 14.7 0.5 0.054 13.8 0.5 1.5 1 1 0 1 1 1 0 RWD domain IHABP4_N PF16174.5 EGG15003.1 - 1.3 9.6 9.5 1.9 9.1 9.5 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal WASH_WAHD PF11945.8 EGG15006.1 - 5.7e-52 177.1 0.0 9.2e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 WAHD domain of WASH complex SIP1 PF04938.12 EGG15006.1 - 5.4e-37 127.6 0.2 5.4e-37 127.6 0.2 1.6 2 0 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) WH2 PF02205.20 EGG15006.1 - 2.4e-05 24.0 0.1 4.5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.19 EGG15006.1 - 1.4 8.4 29.5 1.5e+03 -1.6 30.6 2.9 2 1 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal HSCB_C PF07743.13 EGG15007.1 - 1.2e-19 70.6 8.3 1.2e-19 70.6 8.3 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EGG15007.1 - 2.9e-05 24.1 0.1 8.4e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain T3SSipB PF16535.5 EGG15007.1 - 0.021 15.3 2.2 0.024 15.1 0.2 1.9 2 0 0 2 2 2 0 Type III cell invasion protein SipB zinc_ribbon_15 PF17032.5 EGG15007.1 - 0.027 15.2 3.8 0.061 14.1 3.8 1.7 1 0 0 1 1 1 0 zinc-ribbon family SKA2 PF16740.5 EGG15007.1 - 0.042 13.6 8.6 0.098 12.5 2.1 2.8 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 PLATZ PF04640.14 EGG15007.1 - 0.052 14.2 3.5 0.17 12.5 3.5 1.9 1 0 0 1 1 1 0 PLATZ transcription factor DZR PF12773.7 EGG15007.1 - 0.081 13.0 1.8 0.14 12.2 1.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon HscB_4_cys PF18256.1 EGG15007.1 - 2.9 7.8 4.4 6.4 6.7 4.4 1.6 1 1 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif C1_2 PF03107.16 EGG15007.1 - 4.2 7.8 8.2 0.94 9.9 4.7 1.7 2 0 0 2 2 2 0 C1 domain Actin PF00022.19 EGG15008.1 - 6.9e-134 446.5 0.0 7.8e-134 446.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGG15008.1 - 8.5e-05 21.5 0.0 0.0031 16.4 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Presenilin PF01080.17 EGG15009.1 - 4.3 6.0 5.4 3.8 6.2 5.4 1.0 1 0 0 1 1 1 0 Presenilin DUF2076 PF09849.9 EGG15009.1 - 7.3 6.5 14.9 6.5 6.7 14.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Cyt-b5 PF00173.28 EGG15010.1 - 1.5e-17 63.5 0.0 2.8e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-CDGSH PF09360.10 EGG15010.1 - 8.4e-07 29.1 0.1 2.2e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Acetyltransf_1 PF00583.25 EGG15011.1 - 3.8e-13 49.7 0.0 0.038 14.2 0.0 4.6 4 0 0 4 4 4 4 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG15011.1 - 1.6e-10 41.2 0.6 0.29 11.6 0.0 4.5 4 0 0 4 4 4 4 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGG15011.1 - 6.8e-07 29.3 0.0 2.7 8.2 0.0 4.5 4 0 0 4 4 4 2 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 EGG15011.1 - 8.8e-07 28.9 0.6 4.9 7.1 0.0 5.2 5 0 0 5 5 5 3 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG15011.1 - 0.0044 17.0 2.2 6.8 6.7 0.0 4.6 5 0 0 5 5 5 1 FR47-like protein Acetyltransf_15 PF17013.5 EGG15011.1 - 0.0061 16.0 0.1 36 3.7 0.0 4.1 4 0 0 4 4 4 0 Putative acetyl-transferase zf-RVT PF13966.6 EGG15012.1 - 0.0019 18.8 1.7 0.0061 17.2 0.4 2.4 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase UPF0154 PF03672.13 EGG15014.1 - 0.0021 18.1 0.1 0.0088 16.0 0.1 2.0 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) BRX_N PF13713.6 EGG15014.1 - 0.38 10.6 2.8 10 6.0 0.8 2.4 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain PUF PF00806.19 EGG15016.1 - 2.8e-54 177.8 8.6 4.2e-07 29.3 0.0 9.1 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH PF00642.24 EGG15016.1 - 1.1e-06 28.4 2.3 2.6e-06 27.2 2.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGG15016.1 - 6.3e-06 25.9 3.1 1.5e-05 24.7 3.1 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGG15016.1 - 7.1e-06 25.9 6.5 1.5e-05 24.9 6.5 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 EGG15016.1 - 0.00032 21.4 2.5 0.00032 21.4 2.5 6.9 5 2 1 6 6 6 1 Torus domain zf-CCCH_2 PF14608.6 EGG15016.1 - 0.35 11.4 3.5 0.85 10.2 3.5 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger MYEOV2 PF15004.6 EGG15017.1 - 0.026 15.0 5.9 0.026 15.0 5.9 2.2 1 1 1 2 2 2 0 Myeloma-overexpressed-like tRNA-synt_1d PF00750.19 EGG15018.1 - 1.3e-108 363.0 6.0 1.8e-108 362.6 6.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EGG15018.1 - 5.6e-22 78.1 0.1 1.2e-21 77.1 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EGG15018.1 - 8.7e-09 35.8 0.6 2.8e-08 34.2 0.6 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Cellulase PF00150.18 EGG15019.1 - 4.1e-37 128.1 1.3 7e-37 127.4 1.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HPIP PF15226.6 EGG15019.1 - 0.28 11.6 4.1 0.74 10.2 4.1 1.7 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family SelP_N PF04592.14 EGG15019.1 - 1.8 7.9 12.2 4.6 6.6 12.2 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Innate_immun PF12782.7 EGG15019.1 - 2.1 7.8 9.3 4 6.8 9.3 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Macoilin PF09726.9 EGG15019.1 - 9 4.7 10.1 15 4.0 10.1 1.3 1 0 0 1 1 1 0 Macoilin family Radical_SAM PF04055.21 EGG15021.1 - 1.7e-15 57.8 0.0 5.7e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 EGG15021.1 - 1.5e-06 28.4 1.0 4.9e-06 26.7 0.0 2.3 2 1 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 EGG15021.1 - 0.0028 17.9 0.0 0.0082 16.4 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF1272 PF06906.11 EGG15021.1 - 1.8 8.7 5.4 0.26 11.4 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DUF4209 PF13910.6 EGG15023.1 - 3e-24 85.1 0.1 4.1e-20 71.8 0.1 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) GIT1_C PF12205.8 EGG15023.1 - 0.12 12.5 4.0 0.18 11.9 1.8 2.4 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF4600 PF15372.6 EGG15023.1 - 6 7.3 20.6 0.18 12.2 7.3 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4600) Acyl_transf_3 PF01757.22 EGG15024.1 - 1.9e-20 73.2 29.3 5.3e-20 71.8 29.3 1.8 1 1 0 1 1 1 1 Acyltransferase family Connexin PF00029.19 EGG15024.1 - 2.3e-05 24.3 1.1 5.2e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Connexin NB PF04159.13 EGG15024.1 - 0.055 13.5 0.4 0.2 11.7 0.4 1.9 1 0 0 1 1 1 0 NB glycoprotein COX16 PF14138.6 EGG15024.1 - 0.091 13.3 1.5 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Baculo_11_kDa PF06143.11 EGG15024.1 - 7 6.3 6.7 2.3 7.8 1.5 2.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family Piwi PF02171.17 EGG15025.1 - 2.6e-66 223.9 0.2 4.8e-66 223.0 0.2 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 EGG15025.1 - 7.9e-20 71.1 0.6 1.4e-19 70.3 0.6 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 EGG15025.1 - 0.00034 20.2 0.0 0.00079 19.1 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain Prok-RING_4 PF14447.6 EGG15026.1 - 3e-05 23.8 11.4 6.1e-05 22.8 11.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGG15026.1 - 8.5e-05 22.3 14.4 0.00028 20.7 14.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FUSC-like PF12805.7 EGG15026.1 - 0.61 9.1 4.8 0.88 8.6 4.8 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS zf-RING_5 PF14634.6 EGG15026.1 - 1 9.4 18.1 0.64 10.0 15.9 1.8 2 0 0 2 2 2 0 zinc-RING finger domain E3_UbLigase_R4 PF13764.6 EGG15028.1 - 2.4e-303 1008.4 12.2 3.9e-303 1007.7 0.6 3.8 3 0 0 3 3 3 2 E3 ubiquitin-protein ligase UBR4 ZZ PF00569.17 EGG15028.1 - 8.8e-09 35.1 8.2 8.8e-09 35.1 8.2 3.7 3 0 0 3 3 3 2 Zinc finger, ZZ type DUF4125 PF13526.6 EGG15028.1 - 0.19 11.3 1.9 0.58 9.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4125) UIM PF02809.20 EGG15028.1 - 1.7 8.8 4.5 1.6 8.9 0.7 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif Hydrolase_3 PF08282.12 EGG15029.1 - 2.3e-58 197.9 1.5 2.6e-58 197.7 1.5 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGG15029.1 - 9.2e-09 35.2 0.0 0.00034 20.2 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EGG15029.1 - 0.0002 21.7 0.3 0.012 15.9 0.3 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGG15029.1 - 0.00021 21.4 1.3 0.062 13.4 1.3 3.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG15029.1 - 0.003 18.0 0.0 0.41 11.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase MutL_C PF08676.11 EGG15030.1 - 3.9e-29 101.3 0.0 1.2e-28 99.7 0.0 1.9 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EGG15030.1 - 1.4e-22 79.5 0.0 6.3e-22 77.5 0.0 2.2 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EGG15030.1 - 5.3e-13 49.0 0.2 5.3e-13 49.0 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGG15030.1 - 5.1e-06 27.0 0.0 1.3e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ErmC PF06308.11 EGG15032.1 - 0.22 11.9 0.1 0.38 11.2 0.1 1.3 1 0 0 1 1 1 0 23S rRNA methylastransferase leader peptide (ErmCL) UBX PF00789.20 EGG15033.1 - 6.3e-15 55.2 0.2 1.1e-14 54.4 0.2 1.4 1 0 0 1 1 1 1 UBX domain DUF2368 PF10166.9 EGG15033.1 - 0.35 10.5 5.5 0.66 9.6 5.5 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Glyco_transf_24 PF18404.1 EGG15034.1 - 1.4e-144 480.4 4.5 2.7e-144 479.5 4.5 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EGG15034.1 - 1.8e-44 152.6 10.0 3.3e-44 151.7 5.9 2.7 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EGG15034.1 - 1.7e-29 102.5 5.5 3.1e-28 98.4 2.5 2.7 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EGG15034.1 - 2.5e-28 99.2 6.1 5.1e-28 98.2 5.1 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EGG15034.1 - 2.9e-20 72.4 0.0 8.6e-20 70.9 0.0 1.9 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 EGG15034.1 - 3.1e-08 33.8 6.3 2.3e-07 30.9 1.1 3.6 3 1 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EGG15034.1 - 6.3e-07 29.2 0.3 2.7e-06 27.1 0.3 2.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 SseB_C PF14581.6 EGG15034.1 - 0.022 14.9 0.1 23 5.1 0.0 3.6 3 0 0 3 3 3 0 SseB protein C-terminal domain bZIP_2 PF07716.15 EGG15035.1 - 6.6e-07 29.3 7.0 6.6e-07 29.3 7.0 3.3 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 EGG15035.1 - 9.3e-07 28.9 4.2 9.3e-07 28.9 4.2 3.4 3 0 0 3 3 3 1 bZIP transcription factor SR-25 PF10500.9 EGG15035.1 - 0.00026 20.7 16.0 0.00026 20.7 16.0 3.2 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein Caudo_TAP PF02413.17 EGG15035.1 - 0.02 15.0 2.0 0.02 15.0 2.0 3.8 4 1 1 5 5 5 0 Caudovirales tail fibre assembly protein, lambda gpK DUF3391 PF11871.8 EGG15035.1 - 3.3 8.2 16.0 1.5 9.4 2.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF812 PF05667.11 EGG15035.1 - 6.6 5.5 36.3 0.03 13.2 8.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF812) DUF3450 PF11932.8 EGG15035.1 - 7.4 5.8 25.4 3 7.1 8.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) PBP1_TM PF14812.6 EGG15036.1 - 7.1 7.1 6.3 33 4.9 2.4 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAP_alpha PF03896.16 EGG15038.1 - 1.1e-33 116.7 3.3 1.7e-33 116.1 3.2 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Ras PF00071.22 EGG15039.1 - 1.3e-63 213.4 0.7 1.5e-63 213.2 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG15039.1 - 2.2e-35 121.5 0.1 3.8e-35 120.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG15039.1 - 1.3e-16 60.5 0.2 1.7e-16 60.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG15039.1 - 2.8e-05 23.6 0.1 3.2e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGG15039.1 - 4.7e-05 23.0 0.5 0.00015 21.4 0.3 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG15039.1 - 6.6e-05 23.0 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG15039.1 - 0.00034 20.5 1.1 0.15 12.0 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGG15039.1 - 0.00042 19.8 0.1 0.00068 19.1 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 EGG15039.1 - 0.0012 19.3 0.1 0.031 14.7 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 EGG15039.1 - 0.006 16.1 0.1 0.048 13.2 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_5 PF07728.14 EGG15039.1 - 0.02 14.9 0.1 0.077 13.0 0.0 2.0 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGG15039.1 - 0.036 14.3 0.0 0.066 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG15039.1 - 0.036 14.4 0.0 0.061 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EGG15039.1 - 0.038 13.7 0.1 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain TniB PF05621.11 EGG15039.1 - 0.082 12.3 0.0 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein RhoGAP PF00620.27 EGG15040.1 - 2e-26 92.7 0.2 2e-26 92.7 0.2 2.7 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.23 EGG15040.1 - 9.4e-10 38.7 0.0 2.9e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain YozE_SAM_like PF06855.12 EGG15040.1 - 0.008 16.3 0.1 6.5 7.0 0.0 2.8 2 0 0 2 2 2 2 YozE SAM-like fold Vps5 PF09325.10 EGG15040.1 - 0.07 12.7 5.3 0.058 12.9 1.6 2.5 2 0 0 2 2 2 0 Vps5 C terminal like PP28 PF10252.9 EGG15040.1 - 0.072 13.6 0.2 0.17 12.4 0.2 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 DUF1133 PF06576.11 EGG15040.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) SR-25 PF10500.9 EGG15040.1 - 9.1 5.8 34.4 5.7 6.5 8.0 2.6 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein RNB PF00773.19 EGG15041.1 - 2.3e-49 168.5 1.6 2.3e-49 168.5 1.6 2.5 2 1 0 2 2 2 1 RNB domain DNA_ligase_A_M PF01068.21 EGG15043.1 - 0.014 15.0 1.2 0.032 13.9 1.0 1.8 1 1 0 1 1 1 0 ATP dependent DNA ligase domain Agglutinin_C PF18021.1 EGG15043.1 - 0.032 14.7 0.2 0.11 13.0 0.2 1.9 1 1 0 1 1 1 0 Agglutinin C-terminal DBR1 PF05011.13 EGG15043.1 - 0.033 14.6 0.4 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain G0-G1_switch_2 PF15103.6 EGG15043.1 - 0.1 13.0 0.6 0.22 11.9 0.2 1.8 1 1 1 2 2 2 0 G0/G1 switch protein 2 Med9 PF07544.13 EGG15043.1 - 1.6 8.9 7.6 2.2 8.4 4.9 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF2115 PF09888.9 EGG15043.1 - 1.7 9.2 5.0 15 6.1 3.7 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Glyoxalase_4 PF13669.6 EGG15044.1 - 0.16 12.3 0.1 0.57 10.5 0.1 1.9 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Prefoldin_2 PF01920.20 EGG15046.1 - 3.2e-15 56.0 12.8 3.9e-15 55.7 12.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit KxDL PF10241.9 EGG15046.1 - 0.0051 17.0 4.7 0.083 13.2 0.5 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein CK2S PF15011.6 EGG15046.1 - 0.073 12.9 0.4 0.073 12.9 0.4 1.6 2 0 0 2 2 2 0 Casein Kinase 2 substrate DUF641 PF04859.12 EGG15046.1 - 0.12 12.7 7.0 0.21 11.9 7.0 1.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) VSG_B PF13206.6 EGG15046.1 - 0.38 10.0 4.5 0.45 9.7 4.5 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain Prefoldin PF02996.17 EGG15046.1 - 0.39 10.7 10.2 0.053 13.4 5.0 1.9 2 0 0 2 2 2 0 Prefoldin subunit TMPIT PF07851.13 EGG15046.1 - 1 8.5 5.0 1.2 8.3 5.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Ribosomal_L6e PF01159.19 EGG15046.1 - 1.2 9.7 9.6 2.3 8.8 9.5 1.6 1 1 0 1 1 1 0 Ribosomal protein L6e Osmo_CC PF08946.10 EGG15046.1 - 2 8.7 13.1 1.4 9.2 8.0 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Sep15_SelM PF08806.11 EGG15047.1 - 2.8e-16 59.4 0.2 3e-16 59.3 0.2 1.0 1 0 0 1 1 1 1 Sep15/SelM redox domain eIF-3_zeta PF05091.12 EGG15049.1 - 5.9e-169 563.4 0.8 6.8e-169 563.2 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 EGG15049.1 - 1.8e-05 24.4 0.0 5.1e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 NMDA receptor-regulated gene protein 2 C-terminus ABC_membrane PF00664.23 EGG15050.1 - 6.9e-62 209.6 19.5 6.9e-62 209.6 19.5 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region Peptidase_S8 PF00082.22 EGG15050.1 - 1e-36 126.7 6.7 1e-36 126.7 6.7 1.9 2 0 0 2 2 2 1 Subtilase family ABC_tran PF00005.27 EGG15050.1 - 9.1e-33 113.7 0.0 2e-32 112.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGG15050.1 - 2.2e-07 30.5 0.0 1.7e-06 27.7 0.0 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane_3 PF13748.6 EGG15050.1 - 0.019 14.2 7.3 0.061 12.6 7.3 1.8 1 0 0 1 1 1 0 ABC transporter transmembrane region AAA_22 PF13401.6 EGG15050.1 - 0.036 14.3 0.6 0.15 12.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGG15050.1 - 0.071 12.9 0.5 0.24 11.1 0.5 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EGG15050.1 - 0.075 12.7 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EGG15050.1 - 0.81 8.4 3.4 0.24 10.1 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF4834 PF16118.5 EGG15050.1 - 2.3 9.3 0.0 2.3 9.3 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) zf-CCHC_3 PF13917.6 EGG15051.1 - 2.8e-14 52.8 4.1 4.7e-14 52.1 4.1 1.4 1 0 0 1 1 1 1 Zinc knuckle Cwf_Cwc_15 PF04889.12 EGG15051.1 - 0.0063 16.3 16.1 0.0068 16.2 16.1 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Trypan_PARP PF05887.11 EGG15051.1 - 0.16 12.0 0.1 0.18 11.8 0.1 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CobT PF06213.12 EGG15051.1 - 0.69 9.2 13.4 0.72 9.2 13.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2076 PF09849.9 EGG15051.1 - 0.98 9.4 12.2 1.3 9.0 12.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FAM176 PF14851.6 EGG15051.1 - 1.3 8.7 11.7 2 8.1 11.7 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 EGG15051.1 - 1.4 7.1 16.0 1.4 7.2 16.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.13 EGG15051.1 - 2 6.7 10.9 2 6.7 10.9 1.0 1 0 0 1 1 1 0 Menin SID-1_RNA_chan PF13965.6 EGG15051.1 - 2.8 6.2 8.3 2.6 6.3 8.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Apt1 PF10351.9 EGG15051.1 - 3.8 6.3 20.7 3.9 6.2 20.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Paramyxo_ncap PF00973.19 EGG15051.1 - 4.1 6.2 9.6 4.5 6.1 9.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4820 PF16091.5 EGG15051.1 - 4.2 6.7 13.5 4.9 6.4 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SAPS PF04499.15 EGG15051.1 - 6.6 5.4 13.5 6.9 5.3 13.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 EGG15051.1 - 8.2 4.4 11.5 7.9 4.5 11.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 EGG15051.1 - 8.6 4.8 24.8 8.3 4.8 24.8 1.0 1 0 0 1 1 1 0 Macoilin family Gti1_Pac2 PF09729.9 EGG15052.1 - 0.0066 16.6 1.0 0.0066 16.6 1.0 2.4 2 0 0 2 2 2 1 Gti1/Pac2 family FlbD PF06289.11 EGG15052.1 - 0.053 13.1 0.5 14 5.4 0.0 2.8 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins Ipi1_N PF12333.8 EGG15052.1 - 0.16 12.5 2.0 0.69 10.5 0.8 2.6 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation GET2 PF08690.10 EGG15052.1 - 1.8 8.2 21.0 0.022 14.5 2.1 2.3 2 0 0 2 2 2 0 GET complex subunit GET2 EGF_2 PF07974.13 EGG15053.1 - 2.2e-07 31.1 58.5 0.002 18.4 17.6 3.7 3 0 0 3 3 3 3 EGF-like domain LapA_dom PF06305.11 EGG15053.1 - 0.011 15.5 0.3 0.025 14.4 0.3 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain hEGF PF12661.7 EGG15053.1 - 0.013 16.2 43.0 0.22 12.2 9.8 4.0 3 0 0 3 3 3 0 Human growth factor-like EGF DUF3844 PF12955.7 EGG15053.1 - 0.013 15.6 3.0 0.013 15.6 3.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3844) EGF PF00008.27 EGG15053.1 - 7.7 6.9 53.9 0.46 10.8 12.9 3.7 3 0 0 3 3 3 0 EGF-like domain LRR_8 PF13855.6 EGG15053.1 - 8 6.3 22.4 3.4 7.5 8.3 5.3 3 2 2 5 5 5 0 Leucine rich repeat EB PF01683.18 EGG15053.1 - 9 6.7 40.7 0.16 12.3 7.1 3.8 3 0 0 3 3 3 0 EB module GDP_Man_Dehyd PF16363.5 EGG15054.1 - 6.4e-157 522.1 0.0 9.9e-157 521.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG15054.1 - 4e-74 249.1 0.0 7.6e-74 248.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family eIF-5_eIF-2B PF01873.17 EGG15054.1 - 1.7e-36 124.7 0.1 3.2e-36 123.8 0.1 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EGG15054.1 - 2.6e-18 65.9 1.6 2.6e-18 65.9 1.6 3.0 3 0 0 3 3 2 1 eIF4-gamma/eIF5/eIF2-epsilon RmlD_sub_bind PF04321.17 EGG15054.1 - 0.0015 17.7 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EGG15054.1 - 0.0086 15.7 0.0 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EGG15054.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GATA PF00320.27 EGG15054.1 - 0.14 11.8 0.6 0.3 10.7 0.6 1.5 1 0 0 1 1 1 0 GATA zinc finger SIL1 PF16782.5 EGG15054.1 - 0.14 11.3 5.1 6.4 5.9 4.9 2.4 1 1 1 2 2 2 0 Nucleotide exchange factor SIL1 TLP-20 PF06088.11 EGG15054.1 - 1.6 8.6 9.2 0.66 9.9 0.7 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Pox_Ag35 PF03286.14 EGG15054.1 - 2.3 8.0 15.7 2.5 7.8 4.8 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF1754 PF08555.10 EGG15054.1 - 5.1 7.9 15.5 7.3 7.5 4.2 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) CDC45 PF02724.14 EGG15054.1 - 8 4.6 15.4 1.5 7.0 6.1 2.1 2 0 0 2 2 2 0 CDC45-like protein MFS_1 PF07690.16 EGG15055.1 - 4e-38 131.3 37.3 3.4e-32 111.8 30.4 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG15055.1 - 2.7e-07 29.8 14.9 2.7e-07 29.8 14.9 3.5 3 2 1 4 4 4 2 Sugar (and other) transporter MFS_3 PF05977.13 EGG15055.1 - 0.00018 20.0 4.9 0.00018 20.0 4.9 2.1 1 1 1 2 2 2 2 Transmembrane secretion effector DUF4271 PF14093.6 EGG15055.1 - 0.011 15.6 8.0 0.011 15.6 8.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) DUF2964 PF11177.8 EGG15055.1 - 2 8.7 5.9 0.78 10.0 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) CBS PF00571.28 EGG15057.1 - 6.8e-23 80.9 0.9 9.4e-08 32.4 0.0 4.5 4 0 0 4 4 4 4 CBS domain Ank_2 PF12796.7 EGG15058.1 - 0.021 15.4 9.0 3.5 8.3 0.1 4.7 4 1 0 4 4 4 0 Ankyrin repeats (3 copies) FlgO PF17680.1 EGG15058.1 - 0.073 12.8 0.2 3 7.6 0.0 2.4 2 0 0 2 2 2 0 FlgO protein NES_C_h PF18208.1 EGG15058.1 - 0.17 12.2 1.4 2.7 8.3 0.1 3.0 3 0 0 3 3 3 0 Nicking enzyme C-terminal middle helical domain Acetyltransf_1 PF00583.25 EGG15059.1 - 4e-16 59.3 0.1 5.1e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG15059.1 - 1.3e-08 35.1 0.1 2.4e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG15059.1 - 8.8e-07 28.9 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGG15059.1 - 0.0002 22.0 0.0 0.00034 21.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG15059.1 - 0.002 18.0 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGG15059.1 - 0.0028 17.7 0.0 0.0052 16.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EGG15059.1 - 0.011 15.2 0.1 0.014 14.9 0.1 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase Pro-kuma_activ PF09286.11 EGG15060.1 - 7.2e-26 91.2 0.0 1.3e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGG15060.1 - 8.8e-06 25.2 0.7 1.9e-05 24.1 0.7 1.4 1 0 0 1 1 1 1 Subtilase family FAM110_C PF14160.6 EGG15060.1 - 0.045 14.8 0.0 0.11 13.5 0.0 1.6 1 0 0 1 1 1 0 Centrosome-associated C terminus TMCCDC2 PF15844.5 EGG15060.1 - 0.1 12.5 0.1 7 6.6 0.1 2.4 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 AMP-binding PF00501.28 EGG15061.1 - 4.3e-100 335.3 0.0 5.3e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG15061.1 - 2.4e-15 57.2 0.1 7.8e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pkinase_Tyr PF07714.17 EGG15062.1 - 1.1e-36 126.4 0.0 4.4e-36 124.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGG15062.1 - 3.7e-29 101.9 2.2 9.9e-29 100.5 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain Arm PF00514.23 EGG15062.1 - 5.7e-06 26.2 1.4 0.00098 19.1 0.1 4.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGG15062.1 - 3.6e-05 24.1 0.0 0.013 15.9 0.0 3.8 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 EGG15062.1 - 0.0021 18.2 0.2 0.024 14.8 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat Kdo PF06293.14 EGG15062.1 - 0.11 11.9 0.2 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT_EZ PF13513.6 EGG15062.1 - 0.21 12.2 0.0 4.9 7.8 0.0 2.7 2 0 0 2 2 2 0 HEAT-like repeat Acetyltransf_3 PF13302.7 EGG15063.1 - 2.3e-20 73.7 0.0 2.7e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGG15063.1 - 2.6e-05 24.4 0.1 3.8e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG15063.1 - 0.0041 17.4 0.2 0.0071 16.6 0.0 1.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGG15063.1 - 0.0042 17.0 0.1 0.025 14.5 0.0 2.0 1 1 0 2 2 2 1 FR47-like protein GHL5 PF14872.6 EGG15063.1 - 0.048 11.7 0.0 0.055 11.5 0.0 1.1 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 V-SNARE_C PF12352.8 EGG15063.1 - 0.051 13.9 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus GATase_5 PF13507.6 EGG15064.1 - 1.5e-100 335.6 0.0 2.4e-100 335.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EGG15064.1 - 9.7e-33 113.5 1.8 6e-16 59.0 0.6 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EGG15064.1 - 2.7e-17 62.8 0.0 6.6e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EGG15064.1 - 7.1e-11 42.5 0.0 1.7e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain DUF2605 PF10792.9 EGG15064.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) DUF1604 PF07713.13 EGG15064.1 - 0.16 11.8 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) Ras PF00071.22 EGG15065.1 - 2e-12 47.0 0.6 1.2e-11 44.5 0.0 2.4 3 0 0 3 3 3 1 Ras family Peptidase_C48 PF02902.19 EGG15065.1 - 4.5e-06 26.7 0.0 1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ribosomal_S8 PF00410.19 EGG15065.1 - 0.014 15.4 0.0 0.045 13.7 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein S8 FabA PF07977.13 EGG15066.1 - 0.12 11.9 0.1 4.4 6.9 0.0 2.2 2 0 0 2 2 2 0 FabA-like domain Ras PF00071.22 EGG15067.1 - 6.4e-18 64.9 2.4 2.2e-17 63.1 0.3 2.5 3 0 0 3 3 3 1 Ras family Roc PF08477.13 EGG15067.1 - 0.00012 22.3 1.0 0.005 17.1 0.2 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Presenilin PF01080.17 EGG15068.1 - 9.5 4.9 8.5 13 4.4 8.5 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 EGG15070.1 - 1.6e-295 982.3 4.7 4.7e-295 980.7 4.7 1.6 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family Lebercilin PF15619.6 EGG15070.1 - 0.012 15.3 6.8 0.021 14.5 6.8 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TBK1_CCD1 PF18394.1 EGG15070.1 - 0.039 13.5 0.9 0.063 12.8 0.9 1.3 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 Tropomyosin PF00261.20 EGG15070.1 - 0.051 12.9 5.7 0.08 12.3 5.7 1.2 1 0 0 1 1 1 0 Tropomyosin CorA PF01544.18 EGG15070.1 - 0.16 11.3 2.6 0.34 10.2 2.6 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2937 PF11157.8 EGG15070.1 - 0.2 11.3 0.5 0.6 9.8 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) FapA PF03961.13 EGG15070.1 - 0.41 9.2 3.8 0.64 8.6 3.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A HSBP1 PF06825.12 EGG15070.1 - 0.41 10.5 1.7 5.9 6.8 0.4 2.9 3 0 0 3 3 3 0 Heat shock factor binding protein 1 GHMP_kinases_N PF00288.26 EGG15071.1 - 7.4e-14 51.7 1.3 1.8e-13 50.5 1.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain SSURE PF11966.8 EGG15071.1 - 0.18 11.6 1.0 0.52 10.1 0.2 2.1 3 0 0 3 3 3 0 Fibronectin-binding repeat DUF3106 PF11304.8 EGG15071.1 - 0.23 12.0 3.8 0.56 10.7 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) CLIP_1 PF18322.1 EGG15071.1 - 0.94 9.6 4.6 2.4 8.3 0.8 2.6 2 1 0 2 2 2 0 Serine protease Clip domain PPAF-2 CLASP_N PF12348.8 EGG15072.1 - 1.4e-28 100.0 2.1 1.8e-28 99.6 0.7 1.9 2 0 0 2 2 2 1 CLASP N terminal SKA1 PF07160.12 EGG15072.1 - 0.0083 16.0 3.3 0.0083 16.0 3.3 2.8 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 1 Uds1 PF15456.6 EGG15072.1 - 8.2 6.6 7.9 0.69 10.1 0.5 3.0 3 0 0 3 3 3 0 Up-regulated During Septation FNIP PF05725.12 EGG15073.1 - 1.4e-08 34.7 28.5 0.00094 19.3 0.3 8.6 9 0 0 9 9 9 3 FNIP Repeat F-box-like PF12937.7 EGG15073.1 - 0.00068 19.5 0.0 0.035 14.0 0.0 2.8 2 0 0 2 2 2 1 F-box-like Dickkopf_N PF04706.12 EGG15074.1 - 0.011 16.2 5.2 0.011 16.2 5.2 4.3 3 1 2 5 5 5 0 Dickkopf N-terminal cysteine-rich region DEAD PF00270.29 EGG15075.1 - 3.7e-51 173.4 0.0 6.3e-51 172.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG15075.1 - 4.5e-32 110.7 0.0 1.6e-31 108.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG15075.1 - 1.9e-05 24.7 0.0 3.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FixH PF05751.11 EGG15075.1 - 0.24 11.4 0.6 0.46 10.5 0.6 1.4 1 0 0 1 1 1 0 FixH Phosducin PF02114.16 EGG15076.1 - 4e-20 71.9 0.9 5.1e-20 71.5 0.9 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EGG15076.1 - 0.00012 22.0 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Methyltransf_31 PF13847.6 EGG15077.1 - 1.5e-18 67.1 0.1 2.3e-18 66.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG15077.1 - 2.3e-16 60.3 0.1 5.5e-16 59.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG15077.1 - 3.1e-16 59.8 0.0 5.9e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG15077.1 - 1e-13 51.2 0.0 1.9e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGG15077.1 - 9.6e-11 42.3 0.0 2.1e-10 41.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG15077.1 - 1.1e-08 35.1 0.0 1.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGG15077.1 - 2.9e-07 30.5 0.1 5.2e-07 29.6 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EGG15077.1 - 0.00017 21.3 0.1 0.00028 20.6 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 EGG15077.1 - 0.00032 20.1 0.0 0.00044 19.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 EGG15077.1 - 0.0011 18.7 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DOT1 PF08123.13 EGG15077.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 EGG15077.1 - 0.0028 17.2 0.2 0.006 16.1 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Fibrillarin PF01269.17 EGG15077.1 - 0.0059 15.8 0.1 0.0091 15.1 0.1 1.3 1 1 0 1 1 1 1 Fibrillarin Pox_MCEL PF03291.16 EGG15077.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme FtsJ PF01728.19 EGG15077.1 - 0.021 14.9 0.1 0.029 14.5 0.1 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 EGG15077.1 - 0.1 12.6 0.1 0.23 11.4 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain PARG_cat PF05028.14 EGG15078.1 - 2.4e-124 415.0 0.0 4e-124 414.3 0.0 1.3 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) MAJIN PF15077.6 EGG15078.1 - 2.4 7.9 9.2 3.9 7.2 9.2 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Peptidase_M48 PF01435.18 EGG15079.1 - 7.7e-35 120.5 0.0 1.7e-34 119.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M48 SR-25 PF10500.9 EGG15079.1 - 1.7 8.2 6.4 3.6 7.2 6.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FKBP_C PF00254.28 EGG15080.1 - 4.5e-30 103.8 0.1 6.1e-30 103.4 0.1 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ras PF00071.22 EGG15081.1 - 7.9e-40 136.1 0.0 1.3e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG15081.1 - 6.7e-20 71.5 3.5 1.4e-19 70.5 0.0 2.5 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG15081.1 - 4.4e-05 23.0 0.0 7.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG15081.1 - 0.0027 17.8 0.0 0.0027 17.8 0.0 1.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase La PF05383.17 EGG15082.1 - 1.1e-19 70.2 1.6 1.8e-19 69.5 1.6 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EGG15082.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CoA_binding PF02629.19 EGG15083.1 - 1.3e-31 109.2 0.4 2.7e-31 108.1 0.4 1.6 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 EGG15083.1 - 1e-21 77.4 0.1 1.9e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EGG15083.1 - 1.5e-08 34.5 0.0 2.6e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EGG15083.1 - 0.0058 17.1 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Ccdc124 PF06244.12 EGG15084.1 - 2.9e-32 111.9 33.6 4.5e-28 98.4 33.6 2.8 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 MafB PF06255.13 EGG15084.1 - 0.038 13.4 1.5 0.053 13.0 1.5 1.2 1 0 0 1 1 1 0 Neisseria toxin MafB Peptidase_S64 PF08192.11 EGG15084.1 - 1.7 7.1 14.3 2.2 6.7 14.3 1.3 1 0 0 1 1 1 0 Peptidase family S64 Vfa1 PF08432.10 EGG15084.1 - 4.2 7.7 25.7 6.4 7.1 25.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GREB1 PF15782.5 EGG15084.1 - 7.4 3.5 13.8 8.8 3.3 13.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MFAP1 PF06991.11 EGG15085.1 - 8.9e-51 172.8 36.7 8.9e-51 172.8 36.7 2.1 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing EGF_2 PF07974.13 EGG15086.1 - 0.3 11.5 16.0 0.63 10.5 16.0 1.6 1 0 0 1 1 1 0 EGF-like domain zf-RVT PF13966.6 EGG15087.1 - 0.00038 21.1 0.5 0.0011 19.6 0.5 1.9 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Alpha-amylase PF00128.24 EGG15088.1 - 2.6e-13 50.3 0.0 2.6e-13 50.3 0.0 5.2 5 1 0 5 5 5 1 Alpha amylase, catalytic domain Nucleoporin_C PF03177.14 EGG15088.1 - 2.9e-11 42.8 3.2 2.9e-11 42.8 3.2 2.6 3 0 0 3 3 3 1 Non-repetitive/WGA-negative nucleoporin C-terminal GATA PF00320.27 EGG15088.1 - 1.1e-09 37.7 5.5 2.3e-09 36.7 5.5 1.6 1 0 0 1 1 1 1 GATA zinc finger Tim54 PF11711.8 EGG15089.1 - 0.03 13.1 3.8 0.053 12.3 3.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.8 EGG15089.1 - 0.53 9.1 8.1 2 7.2 6.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 AAR2 PF05282.11 EGG15089.1 - 2.6 7.4 9.4 0.45 9.9 5.9 1.4 2 0 0 2 2 2 0 AAR2 protein DUF913 PF06025.12 EGG15089.1 - 3 6.7 7.8 0.49 9.3 3.5 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) MecA PF05389.12 EGG15090.1 - 0.82 9.3 14.6 0.01 15.5 2.2 2.5 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) FKS1_dom1 PF14288.6 EGG15090.1 - 5.3 7.4 6.5 1.1 9.6 1.4 2.2 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Arm PF00514.23 EGG15091.1 - 2.2e-25 87.8 13.6 0.00015 21.7 0.0 12.6 13 0 0 13 13 13 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGG15091.1 - 3.4e-10 40.2 1.8 0.0064 17.0 0.2 6.8 7 2 1 8 8 8 1 HEAT-like repeat HEAT_2 PF13646.6 EGG15091.1 - 3.9e-09 36.8 0.3 0.23 11.9 0.1 6.2 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.22 EGG15091.1 - 1.7e-08 34.0 9.7 0.039 14.2 0.1 7.9 9 0 0 9 9 9 2 HEAT repeat V-ATPase_H_C PF11698.8 EGG15091.1 - 3.6e-05 23.9 11.8 0.064 13.4 0.1 5.0 3 1 0 5 5 5 2 V-ATPase subunit H DUF4704 PF15787.5 EGG15091.1 - 0.0002 20.7 1.6 0.025 13.8 0.0 3.7 2 2 1 3 3 3 1 Domain of unknown function (DUF4704) IFRD PF05004.13 EGG15091.1 - 0.00081 18.6 1.4 0.054 12.6 0.1 3.2 2 1 1 3 3 3 1 Interferon-related developmental regulator (IFRD) Tti2 PF10521.9 EGG15091.1 - 0.0022 17.6 0.9 0.012 15.2 0.0 2.6 2 2 1 3 3 3 1 Tti2 family DUF3361 PF11841.8 EGG15091.1 - 0.0041 17.1 21.3 0.3 11.0 1.6 5.0 2 2 1 4 4 4 3 Domain of unknown function (DUF3361) Herpes_UL37_1 PF03970.13 EGG15091.1 - 0.0089 15.2 0.1 1.9 7.6 0.0 2.3 2 0 0 2 2 2 2 Herpesvirus UL37 tegument protein IBN_N PF03810.19 EGG15091.1 - 0.018 15.0 7.0 4.7 7.2 0.0 4.5 5 0 0 5 5 5 0 Importin-beta N-terminal domain Atx10homo_assoc PF09759.9 EGG15091.1 - 0.049 13.6 0.1 0.049 13.6 0.1 5.6 6 2 0 6 6 6 0 Spinocerebellar ataxia type 10 protein domain CTNNBL PF08216.11 EGG15091.1 - 0.9 9.7 5.4 22 5.3 0.0 3.8 5 0 0 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear EloA-BP1 PF15870.5 EGG15092.1 - 0.0031 17.8 0.0 0.0031 17.8 0.0 4.4 4 0 0 4 4 4 1 ElonginA binding-protein 1 Macoilin PF09726.9 EGG15092.1 - 0.34 9.4 22.6 0.041 12.4 11.5 2.1 2 0 0 2 2 2 0 Macoilin family ChlamPMP_M PF07548.11 EGG15092.1 - 1.2 9.0 17.1 0.03 14.3 8.2 2.5 2 1 0 2 2 2 0 Chlamydia polymorphic membrane protein middle domain BUD22 PF09073.10 EGG15092.1 - 1.3 8.3 28.1 2.8 7.2 16.2 2.2 2 0 0 2 2 2 0 BUD22 DUF3439 PF11921.8 EGG15092.1 - 3.5 7.6 12.4 3.4 7.7 2.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF908 PF06012.12 EGG15092.1 - 4.2 6.7 23.9 0.2 11.0 3.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Ecl1 PF12855.7 EGG15092.1 - 9.6 7.3 24.1 18 6.4 11.7 2.4 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Dicty_CTDC PF00526.18 EGG15093.1 - 6.1e-32 109.2 150.5 1.8e-10 40.5 4.0 23.2 21 6 0 21 21 21 11 Dictyostelium (slime mold) repeat RdRP PF05183.12 EGG15093.1 - 1.1 7.8 16.8 18 3.8 0.4 5.9 3 3 4 7 7 7 0 RNA dependent RNA polymerase RNase_P_Rpp14 PF01900.19 EGG15094.1 - 8.2e-12 45.3 0.2 9.9e-12 45.0 0.2 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Ran_BP1 PF00638.18 EGG15095.1 - 1e-12 48.4 1.0 1e-12 48.4 1.0 1.8 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 EGG15095.1 - 0.0028 17.6 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 WH1 domain Macoilin PF09726.9 EGG15095.1 - 0.25 9.9 19.7 0.32 9.5 19.7 1.2 1 0 0 1 1 1 0 Macoilin family PPR_2 PF13041.6 EGG15096.1 - 1.3e-27 95.7 1.9 1.3e-10 41.3 0.0 5.0 3 1 2 5 5 5 4 PPR repeat family PPR PF01535.20 EGG15096.1 - 2.7e-20 71.1 2.1 1.3e-05 25.1 0.0 6.5 6 0 0 6 6 6 3 PPR repeat PPR_1 PF12854.7 EGG15096.1 - 8.8e-18 63.7 0.3 2.1e-10 40.1 0.0 4.8 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 EGG15096.1 - 1.1e-13 51.1 0.0 0.001 18.5 0.0 4.4 3 2 1 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EGG15096.1 - 2.1e-13 50.1 1.7 3.9e-05 23.6 0.0 5.3 3 2 1 4 4 4 3 Pentatricopeptide repeat domain ATP13 PF12921.7 EGG15096.1 - 1.5e-07 31.3 2.9 0.024 14.5 0.0 4.0 3 1 0 3 3 3 2 Mitochondrial ATPase expression PYRIN PF02758.16 EGG15096.1 - 0.031 14.4 1.5 3.1 8.0 0.1 3.5 2 1 1 3 3 3 0 PAAD/DAPIN/Pyrin domain PHP PF02811.19 EGG15096.1 - 0.035 14.4 0.9 0.12 12.7 0.1 2.1 2 0 0 2 2 2 0 PHP domain TPR_15 PF13429.6 EGG15096.1 - 0.069 12.4 0.3 1.7 7.8 0.1 2.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Vps39_1 PF10366.9 EGG15096.1 - 0.41 10.9 6.5 0.14 12.5 0.6 2.9 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 RP-C_C PF11800.8 EGG15096.1 - 4.5 7.3 9.0 18 5.3 1.2 3.8 3 1 1 4 4 4 0 Replication protein C C-terminal region Peptidase_S28 PF05577.12 EGG15097.1 - 1.1e-114 383.7 2.8 1.2e-114 383.5 2.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 EGG15097.1 - 0.004 15.9 0.2 0.0087 14.8 0.2 1.5 1 0 0 1 1 1 1 PS-10 peptidase S37 CRAL_TRIO_2 PF13716.6 EGG15097.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF2321 PF10083.9 EGG15098.1 - 0.2 11.3 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) NUDIX PF00293.28 EGG15099.1 - 4.7e-06 26.7 0.0 0.00036 20.6 0.0 2.9 1 1 0 1 1 1 1 NUDIX domain ETF PF01012.21 EGG15100.1 - 2.2e-40 138.5 0.8 3.6e-40 137.8 0.8 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EGG15100.1 - 2.7e-37 126.7 1.2 7.5e-37 125.2 1.2 1.8 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Snapin_Pallidin PF14712.6 EGG15101.1 - 1.2e-16 60.9 6.5 1.2e-16 60.9 6.5 2.3 3 1 0 3 3 3 1 Snapin/Pallidin DUF4501 PF14946.6 EGG15101.1 - 0.13 12.3 4.2 0.21 11.6 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Menin PF05053.13 EGG15101.1 - 3 6.1 12.5 0.47 8.8 8.9 1.5 1 1 0 1 1 1 0 Menin Mucin PF01456.17 EGG15101.1 - 5.5 7.0 28.2 7.9 6.5 28.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Pex14_N PF04695.13 EGG15101.1 - 8.6 7.0 20.0 6 7.5 12.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apis_Csd PF11671.8 EGG15101.1 - 8.7 6.4 10.3 0.5 10.4 3.3 2.1 2 0 0 2 2 2 0 Complementary sex determiner protein Cys_Met_Meta_PP PF01053.20 EGG15102.1 - 1.9e-124 415.1 0.0 2.3e-124 414.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGG15102.1 - 3e-06 26.7 0.0 4.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGG15102.1 - 8.6e-05 21.7 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGG15102.1 - 0.0026 17.1 0.0 0.0066 15.8 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 EGG15102.1 - 0.0031 16.1 0.0 0.0048 15.5 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Crinivirus_P26 PF07416.11 EGG15102.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Crinivirus P26 protein RINT1_TIP1 PF04437.13 EGG15103.1 - 1.2e-64 219.1 14.2 3.1e-56 191.3 5.2 3.6 4 0 0 4 4 4 2 RINT-1 / TIP-1 family ArfGap PF01412.18 EGG15103.1 - 5.5e-25 87.7 3.4 5.5e-25 87.7 3.4 3.2 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf SH3_9 PF14604.6 EGG15103.1 - 3.5e-13 49.2 0.1 7e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGG15103.1 - 1.8e-10 40.3 0.1 4.2e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG15103.1 - 4.4e-08 32.7 0.0 9.2e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RBD PF02196.15 EGG15103.1 - 0.0056 16.7 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 Raf-like Ras-binding domain DUF2070 PF09843.9 EGG15104.1 - 0.0053 15.1 1.0 0.0053 15.1 1.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) DUF3043 PF11241.8 EGG15104.1 - 0.43 10.6 2.5 0.59 10.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Sulfate_transp PF00916.20 EGG15105.1 - 1.3e-56 192.1 12.0 2e-56 191.4 12.0 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGG15105.1 - 2.5e-20 72.2 0.3 4.5e-20 71.4 0.3 1.4 1 0 0 1 1 1 1 STAS domain Na_trans_assoc PF06512.13 EGG15105.1 - 0.043 14.1 0.6 0.089 13.1 0.6 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Rer1 PF03248.13 EGG15106.1 - 5.7e-67 224.7 8.3 6.6e-67 224.5 8.3 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 EGG15106.1 - 1.6 8.3 10.6 0.12 12.0 3.5 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Alpha_kinase PF02816.18 EGG15107.1 - 3.2e-55 187.1 0.3 5.8e-55 186.3 0.3 1.5 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.32 EGG15107.1 - 9.6e-19 67.4 13.1 0.0014 19.4 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat WD40_like PF17005.5 EGG15107.1 - 4.5e-11 42.6 0.3 4.2e-07 29.6 0.2 2.2 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 EGG15107.1 - 2e-07 30.0 14.5 0.00052 18.8 0.4 4.6 2 2 3 6 6 6 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGG15107.1 - 5.1e-05 23.5 2.0 0.21 11.9 0.3 3.8 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4915 PF16261.5 EGG15107.1 - 0.0028 17.0 0.4 0.012 14.9 0.2 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4915) PQQ_3 PF13570.6 EGG15107.1 - 0.017 15.6 0.6 24 5.6 0.0 4.8 5 1 1 6 6 6 0 PQQ-like domain Ge1_WD40 PF16529.5 EGG15107.1 - 0.07 12.1 4.5 1.6 7.6 0.2 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HPS3_N PF14761.6 EGG15107.1 - 0.087 12.4 0.5 12 5.4 0.0 2.5 1 1 1 2 2 2 0 Hermansky-Pudlak syndrome 3 Kelch_1 PF01344.25 EGG15108.1 - 5.4e-18 64.3 9.3 0.00071 19.1 0.4 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EGG15108.1 - 8.8e-16 57.6 13.7 4.4e-05 23.6 0.2 5.8 4 1 2 6 6 6 4 Kelch motif Kelch_4 PF13418.6 EGG15108.1 - 9.4e-16 57.6 6.7 0.0077 16.2 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain zf-B_box PF00643.24 EGG15108.1 - 1.4e-09 37.9 8.8 1.4e-09 37.9 8.8 1.7 2 0 0 2 2 2 1 B-box zinc finger Kelch_3 PF13415.6 EGG15108.1 - 3.4e-07 30.4 2.2 0.083 13.2 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG15108.1 - 0.0058 16.6 11.9 2 8.5 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 EGG15108.1 - 0.021 14.8 11.0 3.1 7.9 0.0 4.8 5 0 0 5 5 5 0 Kelch motif CHCH PF06747.13 EGG15109.1 - 3e-05 24.0 6.3 4.1e-05 23.6 6.3 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EGG15109.1 - 0.00077 19.4 5.2 0.0011 18.9 5.2 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 EGG15109.1 - 0.012 15.9 4.9 0.058 13.7 4.9 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 EGG15109.1 - 0.099 12.9 3.6 1.2 9.4 4.3 1.9 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb COX17 PF05051.13 EGG15109.1 - 0.14 12.5 4.2 0.9 9.9 0.4 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EGG15109.1 - 0.21 11.6 4.5 0.5 10.4 0.5 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3430 PF11912.8 EGG15110.1 - 2e-20 73.8 29.9 2.4e-20 73.5 29.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) FANCI_S2 PF14676.6 EGG15112.1 - 0.02 15.2 0.5 0.15 12.3 0.0 2.7 2 1 0 2 2 2 0 FANCI solenoid 2 MGC-24 PF05283.11 EGG15112.1 - 9.7 6.6 16.2 14 6.1 2.0 2.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SSP160 PF06933.11 EGG15113.1 - 0.06 11.5 26.0 0.065 11.4 26.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AJAP1_PANP_C PF15298.6 EGG15113.1 - 0.29 11.3 15.6 0.32 11.2 15.6 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus TMEM154 PF15102.6 EGG15113.1 - 1.3 9.0 10.2 1.4 8.8 10.2 1.1 1 0 0 1 1 1 0 TMEM154 protein family Dicty_REP PF05086.12 EGG15113.1 - 4.3 5.2 15.1 6 4.7 15.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 EGG15113.1 - 6.2 6.8 38.2 7.7 6.5 38.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Coiled PF05710.12 EGG15114.1 - 0.098 13.5 2.0 0.14 13.0 2.0 1.3 1 0 0 1 1 1 0 Coiled coil DNA_pol3_delta2 PF13177.6 EGG15115.1 - 1e-12 48.1 0.0 1.6e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EGG15115.1 - 1.4e-05 25.5 0.0 3.9e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EGG15115.1 - 5e-05 23.6 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 EGG15115.1 - 7.5e-05 22.7 0.1 0.0003 20.8 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 EGG15115.1 - 0.0098 16.3 0.0 0.028 14.8 0.0 1.7 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 EGG15115.1 - 0.011 15.8 0.1 0.093 12.8 0.1 2.3 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 EGG15115.1 - 0.022 14.8 0.0 0.058 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGG15115.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGG15115.1 - 0.18 12.3 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Pro_isomerase PF00160.21 EGG15116.1 - 4.6e-51 173.2 0.7 5.2e-51 173.0 0.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4958 PF16319.5 EGG15116.1 - 0.031 12.3 0.1 0.039 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4958) ECH_2 PF16113.5 EGG15117.1 - 2.1e-121 405.5 0.0 2.4e-121 405.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGG15117.1 - 2e-24 86.3 0.0 6.5e-22 78.1 0.0 2.5 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF2063 PF09836.9 EGG15117.1 - 0.027 14.7 0.0 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 Putative DNA-binding domain LOB PF03195.14 EGG15117.1 - 0.11 13.1 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 Lateral organ boundaries (LOB) domain SNF5 PF04855.12 EGG15118.1 - 1.9e-31 109.7 0.6 4.1e-16 59.5 0.1 4.3 1 1 2 3 3 3 2 SNF5 / SMARCB1 / INI1 Macoilin PF09726.9 EGG15118.1 - 0.041 12.5 21.5 0.059 11.9 21.5 1.2 1 0 0 1 1 1 0 Macoilin family Mucin PF01456.17 EGG15118.1 - 6.4 6.8 11.2 15 5.5 11.2 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein SprA-related PF12118.8 EGG15118.1 - 8.6 5.4 44.6 13 4.8 44.6 1.2 1 0 0 1 1 1 0 SprA-related family Sterol_MT_C PF08498.10 EGG15119.1 - 3.8e-22 78.4 0.1 6.7e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EGG15119.1 - 3.1e-17 63.0 0.0 6.4e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG15119.1 - 4.6e-16 59.3 0.0 1.2e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG15119.1 - 1.3e-15 57.6 0.0 2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGG15119.1 - 1.4e-15 57.3 0.0 2.1e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGG15119.1 - 6.4e-13 48.9 0.0 1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG15119.1 - 8.9e-09 36.0 0.1 3.7e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG15119.1 - 1.7e-05 24.3 0.0 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGG15119.1 - 0.00012 21.9 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EGG15119.1 - 0.0041 16.7 0.1 0.023 14.2 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EGG15119.1 - 0.0067 16.0 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 EGG15119.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.11 EGG15119.1 - 0.016 14.2 0.1 0.056 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) UPF0020 PF01170.18 EGG15119.1 - 0.027 14.1 0.0 0.073 12.7 0.0 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 EGG15119.1 - 0.041 13.3 0.0 9.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EGG15119.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HEAT PF02985.22 EGG15121.1 - 6.2e-06 26.0 1.0 0.026 14.7 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EGG15121.1 - 1.3e-05 25.7 0.2 0.00019 22.0 0.1 2.8 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region TIP120 PF08623.10 EGG15121.1 - 0.00052 19.8 0.7 0.0058 16.4 0.5 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EGG15121.1 - 0.0046 17.3 0.0 0.021 15.2 0.0 2.1 2 0 0 2 2 2 1 HEAT repeats Tti2 PF10521.9 EGG15121.1 - 0.01 15.4 4.1 0.061 12.8 0.4 3.0 2 1 2 4 4 4 0 Tti2 family RTP1_C1 PF10363.9 EGG15121.1 - 0.021 15.0 0.9 0.39 10.9 0.1 2.6 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 CdiI_N PF18228.1 EGG15121.1 - 0.036 13.9 0.2 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 CdiI N-terminal domain DUF4364 PF14277.6 EGG15122.1 - 0.004 16.9 0.4 0.011 15.5 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) Furin-like_2 PF15913.5 EGG15123.1 - 0.042 14.0 0.3 0.042 14.0 0.3 4.0 4 1 1 5 5 5 0 Furin-like repeat, cysteine-rich Gp37 PF09646.10 EGG15123.1 - 0.097 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Gp37 protein zinc_ribbon_5 PF13719.6 EGG15123.1 - 0.2 11.4 5.7 0.048 13.4 0.8 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L37e PF01907.19 EGG15123.1 - 1.1 9.4 6.5 0.45 10.7 0.2 3.3 3 0 0 3 3 3 0 Ribosomal protein L37e MIT PF04212.18 EGG15125.1 - 1.5e-16 60.2 2.2 1.8e-16 59.9 2.2 1.1 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain MIT PF04212.18 EGG15126.1 - 1.5e-11 44.2 0.6 3.8e-11 42.9 0.6 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Kelch_6 PF13964.6 EGG15126.1 - 2.2e-07 30.9 0.3 0.12 12.7 0.0 5.5 4 1 1 5 5 5 2 Kelch motif SUIM_assoc PF16619.5 EGG15126.1 - 0.00054 20.0 2.4 0.00054 20.0 2.4 3.1 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Kelch_4 PF13418.6 EGG15126.1 - 0.061 13.3 0.1 1.3 9.1 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF2894 PF11445.8 EGG15126.1 - 0.27 11.7 10.4 2.2 8.7 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2894) TPR_8 PF13181.6 EGG15126.1 - 0.36 11.2 2.7 7.4 7.1 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC_CDC26 PF10471.9 EGG15126.1 - 4 8.4 18.1 6 7.8 8.3 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DSPc PF00782.20 EGG15127.1 - 2.3e-29 101.9 3.2 6.6e-29 100.4 0.2 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG15127.1 - 0.00011 21.8 1.1 0.00024 20.7 0.0 2.1 3 0 0 3 3 3 1 Protein-tyrosine phosphatase FtsK_gamma PF09397.10 EGG15127.1 - 0.042 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Ftsk gamma domain HH_signal PF01085.18 EGG15127.1 - 0.36 10.5 3.0 5.3 6.7 0.9 2.2 1 1 1 2 2 2 0 Hedgehog amino-terminal signalling domain SUIM_assoc PF16619.5 EGG15127.1 - 0.52 10.4 8.5 0.032 14.3 1.4 2.3 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cyclin_N PF00134.23 EGG15128.1 - 1.6e-11 44.0 0.2 3.5e-09 36.5 0.0 2.3 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EGG15128.1 - 0.0005 20.4 0.2 0.0012 19.2 0.1 1.7 1 1 0 1 1 1 1 Cyclin C-terminal domain Cyclin_C PF02984.19 EGG15128.1 - 0.0011 19.1 0.1 0.0018 18.3 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain TFIIB PF00382.19 EGG15128.1 - 0.012 15.6 0.1 0.041 13.9 0.0 1.9 2 0 0 2 2 2 0 Transcription factor TFIIB repeat RTC PF01137.21 EGG15129.1 - 6.8e-54 182.4 0.0 9.5e-54 181.9 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EGG15129.1 - 1.3e-34 118.8 0.0 2.1e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DM4_12 PF07841.13 EGG15129.1 - 0.049 14.3 0.2 0.12 13.1 0.2 1.7 1 1 0 1 1 1 0 DM4/DM12 family UQ_con PF00179.26 EGG15130.1 - 1.9e-44 150.7 0.1 2.6e-44 150.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ORC5_C PF14630.6 EGG15131.1 - 1.8e-32 113.0 0.4 3.8e-32 111.9 0.4 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus WD40 PF00400.32 EGG15131.1 - 1.7e-08 35.0 2.4 5 8.2 0.1 7.5 7 0 0 7 7 7 2 WD domain, G-beta repeat AAA_16 PF13191.6 EGG15131.1 - 0.04 14.3 0.0 0.077 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MutS_V PF00488.21 EGG15132.1 - 7e-74 247.9 0.3 1.7e-73 246.7 0.3 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGG15132.1 - 9.6e-39 133.6 0.5 9.6e-39 133.6 0.5 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EGG15132.1 - 1.1e-31 109.3 0.2 3.1e-31 108.0 0.2 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EGG15132.1 - 1.3e-12 48.1 0.0 6.9e-12 45.8 0.0 2.3 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EGG15132.1 - 3.1e-07 30.7 1.9 1.3e-06 28.7 1.9 2.1 1 0 0 1 1 1 1 MutS family domain IV PBP1_TM PF14812.6 EGG15132.1 - 0.28 11.6 30.7 0.14 12.5 12.0 4.0 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Actin PF00022.19 EGG15133.1 - 8.6e-119 396.8 0.0 8.3e-117 390.2 0.0 2.0 1 1 0 1 1 1 1 Actin Actin PF00022.19 EGG15134.1 - 6.4e-100 334.6 0.0 1.2e-98 330.4 0.0 1.9 1 1 0 1 1 1 1 Actin RGS_DHEX PF18148.1 EGG15134.1 - 0.11 12.7 0.1 0.33 11.1 0.1 1.7 2 0 0 2 2 2 0 Regulator of G-protein signalling DHEX domain Pkinase_Tyr PF07714.17 EGG15135.1 - 1.1e-53 182.1 0.0 2.3e-53 181.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG15135.1 - 1.8e-41 142.3 0.0 1.3e-40 139.4 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain PH PF00169.29 EGG15135.1 - 6.2e-16 58.8 1.1 6.2e-16 58.8 1.1 3.0 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 EGG15135.1 - 1.4e-07 31.9 3.1 1.4e-07 31.9 3.1 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain HMG_box PF00505.19 EGG15136.1 - 1.8e-14 53.9 0.7 1.8e-14 53.9 0.7 3.2 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EGG15136.1 - 3.6e-12 46.7 16.7 1.1e-09 38.7 0.6 3.4 3 1 0 3 3 3 2 HMG-box domain DUF3106 PF11304.8 EGG15136.1 - 1.4 9.4 15.0 0.23 11.9 2.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3106) DUF4811 PF16069.5 EGG15138.1 - 0.036 13.9 0.1 0.14 12.0 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) APG12 PF04110.13 EGG15140.1 - 4.5e-28 97.5 0.1 6e-28 97.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EGG15140.1 - 1.6e-07 31.5 0.0 2e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like MID_MedPIWI PF18296.1 EGG15140.1 - 0.0032 17.3 3.6 0.0034 17.2 3.6 1.2 1 0 0 1 1 1 1 MID domain of medPIWI Menin PF05053.13 EGG15140.1 - 2.3 6.5 4.3 2.3 6.5 4.3 1.0 1 0 0 1 1 1 0 Menin Nefa_Nip30_N PF10187.9 EGG15141.1 - 4.9e-11 42.9 17.2 4.9e-11 42.9 17.2 2.6 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 NTP_transf_6 PF06042.11 EGG15141.1 - 0.0023 17.8 0.9 0.0053 16.6 0.9 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase DUF572 PF04502.13 EGG15141.1 - 0.11 12.2 27.2 0.13 11.8 27.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Cwf_Cwc_15 PF04889.12 EGG15141.1 - 9.7 5.8 39.2 0.24 11.1 15.9 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein API5 PF05918.11 EGG15142.1 - 6.8e-141 470.6 16.5 8.1e-141 470.4 16.5 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) Adaptin_N PF01602.20 EGG15142.1 - 0.0014 17.3 1.5 0.004 15.8 0.3 2.0 1 1 1 2 2 2 1 Adaptin N terminal region IFN-gamma PF00714.17 EGG15142.1 - 0.0029 17.4 2.4 0.0046 16.8 0.3 2.3 2 0 0 2 2 2 1 Interferon gamma DUF5340 PF17275.2 EGG15142.1 - 0.0053 16.9 0.0 0.48 10.6 0.0 3.3 2 0 0 2 2 2 1 Family of unknown function (DUF5340) FANCI_S2 PF14676.6 EGG15142.1 - 0.0093 16.3 2.3 0.044 14.1 0.0 2.5 2 0 0 2 2 2 1 FANCI solenoid 2 DUF4303 PF14136.6 EGG15142.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) B56 PF01603.20 EGG15142.1 - 0.092 11.7 8.4 0.084 11.8 5.0 2.2 1 1 1 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) tRNA_lig_CPD PF08302.11 EGG15142.1 - 4.3 6.7 10.4 2.7 7.4 7.6 2.0 1 1 1 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain PH PF00169.29 EGG15143.1 - 5.5e-17 62.2 1.5 5.5e-17 62.2 1.5 2.5 3 0 0 3 3 3 1 PH domain PH_8 PF15409.6 EGG15143.1 - 3.8e-06 27.1 0.2 8.4e-06 26.0 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EGG15143.1 - 8.4e-05 23.0 15.3 0.0014 19.0 3.2 4.2 3 1 0 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 EGG15143.1 - 0.00037 20.5 0.8 0.00087 19.4 0.8 1.6 1 0 0 1 1 1 1 PH domain SOG2 PF10428.9 EGG15143.1 - 0.0053 16.0 22.2 0.0063 15.8 22.2 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein Trnau1ap PF17654.1 EGG15143.1 - 0.01 16.7 0.7 0.01 16.7 0.7 2.6 1 1 1 2 2 2 0 Selenocysteine tRNA 1 associated proteins PH_13 PF16652.5 EGG15143.1 - 0.053 13.3 0.5 0.053 13.3 0.5 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Adap_comp_sub PF00928.21 EGG15144.1 - 3.4e-18 66.0 0.5 5.3e-18 65.3 0.5 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGG15144.1 - 1.3e-06 28.4 0.4 2.4e-06 27.5 0.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AA_kinase PF00696.28 EGG15145.1 - 1.2e-35 123.2 0.1 8.8e-34 117.2 0.1 2.1 1 1 0 1 1 1 1 Amino acid kinase family 5_nucleotid PF05761.14 EGG15146.1 - 2.2e-56 191.7 3.2 2.2e-56 191.7 3.2 1.5 1 1 1 2 2 2 1 5' nucleotidase family HAD_2 PF13419.6 EGG15146.1 - 0.0019 18.3 0.4 0.025 14.7 0.1 2.7 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase HNOB PF07700.15 EGG15146.1 - 0.045 13.7 0.1 0.4 10.6 0.0 2.5 2 0 0 2 2 2 0 Haem-NO-binding Ribosomal_L18p PF00861.22 EGG15146.1 - 0.16 12.4 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast S10_plectin PF03501.15 EGG15147.1 - 6.1e-38 128.8 0.1 7.4e-38 128.5 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Nucleopor_Nup85 PF07575.13 EGG15148.1 - 4.5e-10 38.7 5.5 5.8e-10 38.4 5.5 1.1 1 0 0 1 1 1 1 Nup85 Nucleoporin DpnI_C PF17726.1 EGG15148.1 - 0.083 13.0 0.4 0.083 13.0 0.4 2.3 1 1 1 2 2 2 0 Dam-replacing HTH domain EcoR124_C PF12008.8 EGG15149.1 - 0.018 14.7 1.3 0.018 14.7 1.3 2.9 3 0 0 3 3 3 0 Type I restriction and modification enzyme - subunit R C terminal DUF3574 PF12098.8 EGG15149.1 - 0.077 12.8 2.3 3 7.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3574) Fer4_14 PF13394.6 EGG15149.1 - 0.088 12.9 0.3 0.92 9.7 0.1 2.8 2 1 1 3 3 3 0 4Fe-4S single cluster domain DUF3467 PF11950.8 EGG15149.1 - 0.12 12.6 0.1 16 5.8 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) Pkinase PF00069.25 EGG15150.1 - 1.9e-17 63.5 0.0 1.6e-16 60.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG15150.1 - 2.3e-12 46.8 0.0 4.5e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG15150.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like HEAT PF02985.22 EGG15150.1 - 0.034 14.4 0.0 33 5.1 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Nop14 PF04147.12 EGG15150.1 - 6 4.9 15.6 10 4.2 15.6 1.2 1 0 0 1 1 1 0 Nop14-like family adh_short PF00106.25 EGG15151.1 - 2e-16 60.0 0.0 2.7e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG15151.1 - 6.9e-11 42.1 0.0 1.7e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase CENP-B_dimeris PF09026.10 EGG15151.1 - 0.0095 16.3 3.5 0.0095 16.3 3.5 2.3 2 0 0 2 2 2 1 Centromere protein B dimerisation domain ATG27 PF09451.10 EGG15152.1 - 5.8e-06 26.4 0.6 0.00042 20.3 0.3 2.3 2 1 0 2 2 2 2 Autophagy-related protein 27 PRKCSH_1 PF13015.6 EGG15152.1 - 0.024 14.3 0.9 0.033 13.9 0.4 1.4 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein TIG PF01833.24 EGG15153.1 - 4.4e-46 154.9 145.5 7.9e-06 25.9 3.9 16.8 16 2 2 18 18 18 15 IPT/TIG domain EGF_2 PF07974.13 EGG15153.1 - 0.0006 20.1 15.7 0.0014 18.9 15.7 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG15153.1 - 0.1 12.7 15.4 0.3 11.2 15.4 1.9 1 0 0 1 1 1 0 Tenascin EGF domain Laminin_EGF PF00053.24 EGG15153.1 - 0.11 12.6 11.8 0.22 11.7 11.8 1.4 1 0 0 1 1 1 0 Laminin EGF domain EGF PF00008.27 EGG15153.1 - 0.17 12.2 7.8 0.41 11.0 7.8 1.7 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGG15153.1 - 5.1 7.9 6.2 15 6.4 6.2 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF CBM_X2 PF03442.14 EGG15153.1 - 6.8 6.9 16.0 8.7 6.5 1.3 6.6 7 0 0 7 7 7 0 Carbohydrate binding domain X2 EGF_alliinase PF04863.13 EGG15153.1 - 9.2 6.8 7.7 8.8 6.8 5.3 2.2 2 0 0 2 2 2 0 Alliinase EGF-like domain PRKCSH_1 PF13015.6 EGG15154.1 - 0.007 16.1 0.5 0.011 15.4 0.5 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF4290 PF14123.6 EGG15155.1 - 0.068 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) zf-BED PF02892.15 EGG15155.1 - 1.1 9.4 4.1 0.3 11.1 0.4 1.9 2 0 0 2 2 2 0 BED zinc finger zf-RVT PF13966.6 EGG15156.1 - 0.00065 20.4 0.0 0.002 18.8 0.0 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase FAT PF02259.23 EGG15157.1 - 1.1e-107 360.2 3.5 1.1e-107 360.2 3.5 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EGG15157.1 - 1.1e-72 244.9 0.2 3.1e-72 243.4 0.2 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EGG15157.1 - 5.4e-67 224.7 2.9 6.3e-60 201.7 0.0 5.7 4 2 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EGG15157.1 - 2.9e-41 139.9 0.5 2.9e-41 139.9 0.5 3.7 4 0 0 4 4 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 EGG15157.1 - 1.1e-16 60.4 0.4 3.4e-16 58.8 0.4 2.0 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 EGG15157.1 - 1.9e-15 57.0 14.3 0.041 14.3 0.0 9.5 7 2 2 9 9 9 4 HEAT repeats HEAT PF02985.22 EGG15157.1 - 6.6e-14 50.8 19.4 0.014 15.6 0.0 11.7 12 0 0 12 12 10 2 HEAT repeat Cnd1 PF12717.7 EGG15157.1 - 1e-08 35.4 5.6 0.17 11.9 0.0 6.0 5 2 1 7 7 6 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 EGG15157.1 - 1.1e-08 35.5 7.8 0.00013 22.2 0.3 6.0 4 2 1 5 5 5 1 Parkin co-regulated protein HEAT_EZ PF13513.6 EGG15157.1 - 1.3e-08 35.2 20.7 0.00042 20.7 0.1 10.9 12 1 1 13 13 11 2 HEAT-like repeat Sec7_N PF12783.7 EGG15157.1 - 3.9e-07 30.1 3.6 0.18 11.7 0.0 5.9 5 1 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal UME PF08064.13 EGG15157.1 - 2.6e-06 27.3 9.1 0.035 14.0 0.1 7.3 7 2 2 9 9 9 2 UME (NUC010) domain V-ATPase_H_N PF03224.14 EGG15157.1 - 8.4e-06 25.3 0.4 1.6 8.0 0.1 3.6 3 0 0 3 3 3 3 V-ATPase subunit H IFRD PF05004.13 EGG15157.1 - 0.00039 19.6 0.7 0.033 13.3 0.0 3.8 3 1 1 4 4 4 1 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 EGG15157.1 - 0.00093 19.7 5.7 19 6.0 0.0 6.6 7 2 1 8 8 6 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGG15157.1 - 0.012 15.2 1.5 1.9 8.0 0.0 4.7 5 1 1 6 6 6 0 CLASP N terminal TPR_12 PF13424.6 EGG15157.1 - 0.014 15.7 0.5 1.9 8.8 0.0 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG15157.1 - 0.065 13.3 1.1 10 6.4 0.1 3.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Gp_dh_C PF02800.20 EGG15158.1 - 2.5e-62 209.1 0.0 3.7e-62 208.6 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EGG15158.1 - 2.1e-36 124.3 0.1 5.3e-36 123.0 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EGG15158.1 - 0.041 14.0 0.1 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RCR PF12273.8 EGG15159.1 - 0.00061 20.4 0.6 0.0011 19.6 0.6 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 EGG15159.1 - 0.023 15.6 1.6 0.023 15.6 1.6 1.9 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.7 EGG15159.1 - 0.03 12.7 0.1 0.037 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MAP17 PF15807.5 EGG15159.1 - 0.16 12.2 0.0 5.4 7.3 0.0 2.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Sensor PF13796.6 EGG15160.1 - 0.037 14.1 0.2 0.059 13.4 0.2 1.3 1 0 0 1 1 1 0 Putative sensor NrfD PF03916.14 EGG15160.1 - 0.039 13.6 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysulphide reductase, NrfD EphA2_TM PF14575.6 EGG15160.1 - 0.051 14.5 0.7 0.073 14.0 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ndc1_Nup PF09531.10 EGG15160.1 - 0.078 11.7 0.1 0.1 11.3 0.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TMEM191C PF15194.6 EGG15160.1 - 0.081 13.1 0.1 0.13 12.4 0.0 1.4 2 0 0 2 2 2 0 TMEM191C family DUF5134 PF17197.4 EGG15160.1 - 0.32 10.9 3.3 0.44 10.4 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) Adeno_E3_CR2 PF02439.15 EGG15161.1 - 9.4e-05 22.1 7.7 0.0002 21.0 7.7 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 EGG15161.1 - 0.0016 17.8 7.7 0.0016 17.8 7.7 2.1 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Shisa PF13908.6 EGG15161.1 - 0.0069 16.7 0.2 0.0095 16.2 0.2 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3827 PF12877.7 EGG15161.1 - 0.014 13.8 0.0 0.017 13.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) TMEM52 PF14979.6 EGG15161.1 - 0.015 15.2 0.9 0.015 15.2 0.9 1.5 2 0 0 2 2 1 0 Transmembrane 52 EphA2_TM PF14575.6 EGG15161.1 - 0.023 15.6 0.1 0.023 15.6 0.1 1.7 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM132D_C PF15706.5 EGG15161.1 - 0.038 13.8 0.7 0.062 13.1 0.7 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4448 PF14610.6 EGG15161.1 - 0.084 12.6 0.7 0.12 12.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Stevor PF17410.2 EGG15161.1 - 0.16 11.5 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 EGG15161.1 - 0.29 11.0 0.0 0.4 10.6 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family LRRC37AB_C PF14914.6 EGG15161.1 - 0.32 10.9 1.0 0.51 10.2 1.0 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF2207 PF09972.9 EGG15161.1 - 0.41 9.4 0.3 0.44 9.2 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Mito_carr PF00153.27 EGG15162.1 - 5.9e-54 180.0 0.3 5.4e-23 80.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PLA2_B PF01735.18 EGG15162.1 - 0.16 10.4 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain PAP_assoc PF03828.19 EGG15163.1 - 2.5e-11 43.6 0.7 4.6e-11 42.8 0.7 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase AAA_12 PF13087.6 EGG15164.1 - 5.4e-57 192.6 0.7 1.7e-56 191.0 0.7 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGG15164.1 - 2.7e-50 171.6 1.8 1e-23 84.5 0.1 3.7 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 EGG15164.1 - 9.9e-14 51.9 0.0 2.6e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG15164.1 - 2e-13 50.5 0.0 4.9e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain PAP_assoc PF03828.19 EGG15164.1 - 2.8e-11 43.5 2.1 4.7e-11 42.7 0.7 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase Viral_helicase1 PF01443.18 EGG15164.1 - 5.1e-08 32.9 0.0 0.27 10.9 0.0 4.2 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGG15164.1 - 9.1e-05 22.7 0.2 0.00037 20.8 0.0 2.2 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 EGG15164.1 - 0.00015 21.8 0.4 0.0015 18.5 0.0 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NTP_transf_2 PF01909.23 EGG15164.1 - 0.00017 21.8 0.3 0.0033 17.7 0.1 3.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain PhoH PF02562.16 EGG15164.1 - 0.00019 20.9 0.0 0.0014 18.1 0.0 2.1 1 1 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.21 EGG15164.1 - 0.00044 19.9 6.6 0.0024 17.5 0.0 3.9 3 1 1 4 4 4 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 EGG15164.1 - 0.0042 17.5 0.1 0.028 14.8 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGG15164.1 - 0.0086 15.7 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG15164.1 - 0.013 15.9 0.0 0.039 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Polbeta PF18765.1 EGG15164.1 - 0.031 14.4 0.1 0.23 11.6 0.1 2.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase T2SSE PF00437.20 EGG15164.1 - 0.034 13.2 0.0 0.084 11.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 EGG15164.1 - 0.035 14.6 0.1 0.44 11.1 0.0 3.0 3 1 0 3 3 2 0 AAA domain AAA_5 PF07728.14 EGG15164.1 - 0.049 13.6 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 EGG15164.1 - 0.056 12.7 0.7 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 EGG15164.1 - 0.12 12.2 1.7 1.8 8.3 0.1 2.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_29 PF13555.6 EGG15164.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvrD_C_2 PF13538.6 EGG15164.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ABC_tran PF00005.27 EGG15164.1 - 0.49 10.9 2.5 0.69 10.4 0.2 2.7 2 1 0 2 2 1 0 ABC transporter Laminin_EGF PF00053.24 EGG15166.1 - 0.00012 22.2 21.4 0.011 15.9 3.1 3.2 3 0 0 3 3 3 2 Laminin EGF domain DUF5050 PF16472.5 EGG15166.1 - 0.014 14.7 3.1 0.22 10.7 3.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5050) EGF_2 PF07974.13 EGG15166.1 - 2.3 8.7 15.6 11 6.5 1.6 3.0 2 0 0 2 2 2 0 EGF-like domain Peptidase_S10 PF00450.22 EGG15167.1 - 2.8e-12 46.8 2.1 4.9e-12 46.0 2.1 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase DUF2726 PF10881.8 EGG15169.1 - 0.026 14.4 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) PID_2 PF14719.6 EGG15169.1 - 0.032 14.1 0.8 0.074 12.9 0.4 1.7 1 1 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Astro_capsid_p PF12226.8 EGG15169.1 - 0.035 13.3 20.5 0.06 12.5 20.5 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein MurB_C PF02873.16 EGG15169.1 - 0.046 13.8 0.3 0.82 9.7 0.3 2.2 1 1 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain DUF559 PF04480.12 EGG15169.1 - 0.057 13.3 1.1 3.3 7.6 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF559) F-box-like PF12937.7 EGG15170.1 - 0.0002 21.2 0.0 0.00049 19.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 EGG15170.1 - 0.0028 17.2 0.0 0.0082 15.7 0.0 1.8 1 0 0 1 1 1 1 F-box F-box PF00646.33 EGG15170.1 - 0.019 14.9 0.3 0.076 12.9 0.0 2.1 2 0 0 2 2 2 0 F-box domain Herpes_pp85 PF04637.12 EGG15170.1 - 0.82 8.0 4.6 1.1 7.6 4.6 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) IMUP PF15761.5 EGG15170.1 - 1.6 9.5 8.4 2.3 9.0 8.4 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 EGG15170.1 - 5.4 6.6 11.3 7.5 6.1 11.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FNIP PF05725.12 EGG15172.1 - 9.4e-42 140.9 2.2 1.7e-14 53.7 0.0 4.1 3 0 0 3 3 3 3 FNIP Repeat Phage_min_tail PF05939.13 EGG15172.1 - 0.042 14.2 0.5 25 5.3 0.0 3.7 1 1 2 4 4 4 0 Phage minor tail protein CHASE5 PF17149.4 EGG15172.1 - 0.096 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Periplasmic sensor domain found in signal transduction proteins LRR_11 PF18831.1 EGG15172.1 - 6.3 6.5 14.8 10 5.8 0.1 5.7 7 0 0 7 7 7 0 Leucine-rich repeat Iso_dh PF00180.20 EGG15174.1 - 8.1e-86 288.3 1.4 9.4e-86 288.1 1.4 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase EphA2_TM PF14575.6 EGG15175.1 - 0.043 14.7 0.9 0.16 12.9 0.3 2.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ETRAMP PF09716.10 EGG15175.1 - 0.15 12.1 5.5 3.8 7.6 0.4 3.2 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) S-antigen PF05756.11 EGG15175.1 - 1.2 9.6 3.6 2.8 8.4 0.2 2.2 2 0 0 2 2 2 0 S-antigen protein WW PF00397.26 EGG15176.1 - 1.4e-14 53.8 17.5 7.4e-08 32.4 2.2 2.8 2 0 0 2 2 2 2 WW domain IQ PF00612.27 EGG15176.1 - 2e-10 39.5 7.4 2.8e-05 23.5 0.3 2.4 2 0 0 2 2 2 2 IQ calmodulin-binding motif DIOX_N PF14226.6 EGG15177.1 - 0.00095 19.9 0.0 0.0024 18.6 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGG15177.1 - 0.0033 17.9 0.0 0.0049 17.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DnaJ PF00226.31 EGG15178.1 - 4.1e-21 74.9 0.6 1.3e-20 73.3 0.6 1.9 1 0 0 1 1 1 1 DnaJ domain Pfk_N PF18468.1 EGG15178.1 - 0.018 15.4 2.7 0.14 12.6 0.3 2.5 1 1 1 2 2 2 0 Phosphofructokinase N-terminal domain yeast DUF4229 PF14012.6 EGG15178.1 - 0.48 10.5 4.9 0.88 9.7 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF913 PF06025.12 EGG15178.1 - 0.68 8.9 9.7 1.3 7.9 9.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GAGA_bind PF06217.12 EGG15178.1 - 0.93 9.7 15.7 0.24 11.7 12.9 1.5 2 0 0 2 2 2 0 GAGA binding protein-like family NOA36 PF06524.12 EGG15178.1 - 3.6 6.8 16.5 6.4 6.0 16.5 1.4 1 0 0 1 1 1 0 NOA36 protein CCSAP PF15748.5 EGG15178.1 - 4.1 7.5 21.8 8 6.5 21.8 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Sporozoite_P67 PF05642.11 EGG15178.1 - 6.6 4.7 20.7 10 4.1 20.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CBFD_NFYB_HMF PF00808.23 EGG15179.1 - 9.5e-26 89.9 0.5 1.3e-25 89.4 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGG15179.1 - 0.0014 19.0 0.0 0.0014 19.0 0.0 2.6 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGG15179.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold ubiquitin PF00240.23 EGG15180.1 - 6.8e-10 38.6 0.3 1.3e-09 37.6 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407_C PF13373.6 EGG15180.1 - 2.5e-05 24.5 0.6 3.9e-05 23.9 0.2 1.6 1 1 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EGG15180.1 - 0.00017 22.1 0.5 0.00036 21.0 0.1 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 EGG15180.1 - 0.03 14.1 0.1 0.057 13.2 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DHFR_1 PF00186.19 EGG15180.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrofolate reductase BTB PF00651.31 EGG15182.1 - 8.5e-17 61.4 6.0 3.7e-16 59.3 0.3 3.5 2 1 1 3 3 3 1 BTB/POZ domain VWA_2 PF13519.6 EGG15182.1 - 0.0087 16.7 0.0 0.0087 16.7 0.0 3.3 4 0 0 4 4 4 1 von Willebrand factor type A domain SSP160 PF06933.11 EGG15182.1 - 0.3 9.2 17.3 0.65 8.1 17.3 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Utp14 PF04615.13 EGG15182.1 - 2.3 6.7 27.6 0.019 13.6 19.7 1.5 2 0 0 2 2 2 0 Utp14 protein Pep_M12B_propep PF01562.19 EGG15182.1 - 4.3 7.6 13.6 0.078 13.2 3.4 2.5 2 0 0 2 2 2 0 Reprolysin family propeptide Myotub-related PF06602.14 EGG15183.1 - 7.9e-132 439.4 2.3 7.9e-132 439.4 2.3 2.4 3 1 0 3 3 3 1 Myotubularin-like phosphatase domain FERM_f0 PF16511.5 EGG15183.1 - 6.1e-05 23.2 10.1 0.012 15.9 0.0 6.1 6 0 0 6 6 6 1 N-terminal or F0 domain of Talin-head FERM DSPc PF00782.20 EGG15183.1 - 0.0041 16.9 0.0 0.0041 16.9 0.0 2.6 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain GRAM PF02893.20 EGG15183.1 - 0.0062 16.4 0.0 0.035 14.0 0.0 2.3 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.27 EGG15183.1 - 0.014 15.0 0.9 0.043 13.4 0.0 2.2 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGG15183.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family RNA_pol_A_bac PF01000.26 EGG15184.1 - 7.2e-28 97.2 0.0 2.5e-27 95.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGG15184.1 - 1.6e-23 81.9 0.0 4.2e-23 80.6 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 EGG15184.1 - 0.063 13.5 1.0 0.13 12.4 1.0 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain ECH_1 PF00378.20 EGG15185.1 - 4.2e-25 88.5 0.0 4.9e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGG15185.1 - 1.5e-12 47.7 0.0 1.7e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF2709 PF10915.8 EGG15185.1 - 0.0031 16.8 0.1 0.0058 15.9 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2709) BK_channel_a PF03493.18 EGG15186.1 - 1.2e-19 70.3 0.1 7.9e-19 67.7 0.0 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EGG15186.1 - 3.5e-11 42.9 2.8 1.2e-10 41.2 2.8 2.0 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGG15186.1 - 8.6e-09 35.0 15.6 1.7e-08 34.0 15.6 1.4 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 EGG15186.1 - 1.3e-05 25.4 0.0 0.09 13.0 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain Pkinase PF00069.25 EGG15187.1 - 3.6e-80 269.1 0.0 6.6e-80 268.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG15187.1 - 2.9e-39 134.9 0.0 4.2e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGG15187.1 - 8.3e-15 54.9 0.1 1.8e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EGG15187.1 - 1.6e-06 27.7 0.0 2.1e-05 24.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGG15187.1 - 1.1e-05 24.9 0.1 1.9e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 EGG15187.1 - 3.4e-05 24.1 0.0 8.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RIO1 PF01163.22 EGG15187.1 - 0.017 14.7 0.2 0.017 14.7 0.2 1.7 2 0 0 2 2 2 0 RIO1 family FHA_2 PF17913.1 EGG15187.1 - 0.021 15.1 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 FHA domain Laps PF10169.9 EGG15187.1 - 1.1 9.9 13.4 4.1 8.0 5.7 2.5 2 0 0 2 2 2 0 Learning-associated protein Intein_splicing PF14890.6 EGG15187.1 - 8 6.4 8.7 4.5 7.2 3.3 2.3 2 0 0 2 2 2 0 Intein splicing domain Atx10homo_assoc PF09759.9 EGG15188.1 - 4.1e-32 110.1 8.0 1.5e-31 108.3 1.9 3.7 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain Phosducin PF02114.16 EGG15189.1 - 5.2e-24 84.6 0.9 7.6e-24 84.1 0.9 1.2 1 0 0 1 1 1 1 Phosducin Suf PF05843.14 EGG15189.1 - 0.0035 17.4 1.7 0.0046 17.0 1.7 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) EF-1_beta_acid PF10587.9 EGG15189.1 - 0.017 15.5 0.5 0.057 13.9 0.5 1.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Ank_2 PF12796.7 EGG15191.1 - 2.2e-20 73.0 14.8 0.00054 20.5 0.1 8.3 3 2 2 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG15191.1 - 1.6e-11 44.5 13.2 0.075 13.6 0.1 9.7 8 2 1 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG15191.1 - 7.3e-08 32.1 15.4 11 7.0 0.0 11.9 14 1 1 15 15 15 2 Ankyrin repeat Ank_5 PF13857.6 EGG15191.1 - 2.9e-06 27.4 17.4 1.2 9.5 0.1 10.2 7 2 6 14 14 14 3 Ankyrin repeats (many copies) TFIIA PF03153.13 EGG15191.1 - 8.7 6.2 30.2 13 5.6 30.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PACT_coil_coil PF10495.9 EGG15193.1 - 0.055 14.0 0.4 0.13 12.9 0.2 1.8 2 1 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein M16C_assoc PF08367.11 EGG15194.1 - 1.5e-61 207.7 0.2 2.9e-61 206.8 0.2 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EGG15194.1 - 5.7e-29 101.4 3.2 3.2e-19 69.6 0.2 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGG15194.1 - 3.4e-08 33.6 3.3 8.3e-07 29.1 0.0 3.5 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Met_asp_mut_E PF06368.11 EGG15194.1 - 0.011 14.2 0.2 0.27 9.7 0.0 2.2 2 0 0 2 2 2 0 Methylaspartate mutase E chain (MutE) PNPase PF03726.14 EGG15194.1 - 1.1 9.8 8.4 2 9.0 0.1 3.4 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain AAA PF00004.29 EGG15195.1 - 8.1e-32 110.4 0.0 1.4e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGG15195.1 - 1.2e-08 35.6 0.0 3.5e-08 34.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 EGG15195.1 - 3.5e-08 33.8 0.2 7e-07 29.6 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGG15195.1 - 1.6e-07 31.4 2.5 5.4e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGG15195.1 - 5.3e-06 26.9 0.0 1.5e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EGG15195.1 - 7.3e-05 22.8 2.5 0.68 9.8 0.0 3.2 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGG15195.1 - 0.00011 22.0 0.4 0.0011 18.7 0.0 2.8 2 2 1 3 3 3 1 AAA domain AAA_25 PF13481.6 EGG15195.1 - 0.00016 21.4 0.0 0.085 12.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 EGG15195.1 - 0.00018 21.4 0.0 0.00051 20.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Cytidylate_kin PF02224.18 EGG15195.1 - 0.00022 21.1 0.0 0.00043 20.1 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase RNA_helicase PF00910.22 EGG15195.1 - 0.00025 21.4 0.0 0.0007 20.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Rad17 PF03215.15 EGG15195.1 - 0.00043 20.3 0.2 0.002 18.1 0.1 2.0 2 1 0 2 2 1 1 Rad17 P-loop domain TsaE PF02367.17 EGG15195.1 - 0.00059 19.8 0.3 0.0029 17.6 0.0 2.1 2 1 1 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EGG15195.1 - 0.00074 19.6 3.0 0.0036 17.3 0.1 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 EGG15195.1 - 0.00077 19.6 0.0 0.0014 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EGG15195.1 - 0.00084 19.5 0.0 0.0062 16.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 EGG15195.1 - 0.00087 18.9 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_17 PF13207.6 EGG15195.1 - 0.00092 19.6 0.0 0.0033 17.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 EGG15195.1 - 0.0018 18.0 0.0 0.0065 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGG15195.1 - 0.0019 18.0 1.6 0.0023 17.7 0.1 2.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EGG15195.1 - 0.0023 17.7 0.0 0.006 16.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGG15195.1 - 0.0027 17.5 0.0 0.0062 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 EGG15195.1 - 0.0027 17.7 0.0 0.0086 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EGG15195.1 - 0.0029 17.8 0.0 0.0059 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EGG15195.1 - 0.0031 17.4 0.2 0.028 14.3 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EGG15195.1 - 0.0032 18.0 0.2 0.011 16.3 0.0 1.9 2 0 0 2 2 2 1 ABC transporter KAP_NTPase PF07693.14 EGG15195.1 - 0.0036 16.6 0.3 1.8 7.7 0.0 2.4 1 1 1 2 2 2 1 KAP family P-loop domain TIP49 PF06068.13 EGG15195.1 - 0.0044 16.3 0.0 0.007 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain PduV-EutP PF10662.9 EGG15195.1 - 0.0055 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation CPT PF07931.12 EGG15195.1 - 0.0067 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.9 EGG15195.1 - 0.0077 15.5 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EGG15195.1 - 0.0098 16.2 3.0 0.084 13.2 0.0 2.9 2 1 1 3 3 3 1 AAA domain DnaB_C PF03796.15 EGG15195.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.7 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ATPase PF06745.13 EGG15195.1 - 0.016 14.6 0.3 0.15 11.4 0.0 2.2 1 1 0 2 2 2 0 KaiC Viral_helicase1 PF01443.18 EGG15195.1 - 0.016 15.0 0.1 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 EGG15195.1 - 0.016 15.1 0.1 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 NTPase DUF815 PF05673.13 EGG15195.1 - 0.025 13.8 0.0 0.072 12.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 EGG15195.1 - 0.025 14.0 0.0 0.082 12.4 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 EGG15195.1 - 0.025 14.0 0.0 0.066 12.6 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Cullin_Nedd8 PF10557.9 EGG15195.1 - 0.026 14.6 0.3 0.15 12.1 0.1 2.5 2 0 0 2 2 1 0 Cullin protein neddylation domain T2SSE PF00437.20 EGG15195.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein adh_short PF00106.25 EGG15196.1 - 5.5e-15 55.3 0.0 3.9e-08 33.0 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase PhyH PF05721.13 EGG15196.1 - 3.5e-13 50.3 1.1 1.1e-12 48.7 0.0 2.4 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) adh_short_C2 PF13561.6 EGG15196.1 - 3e-12 46.6 0.0 4.1e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EGG15196.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 EGG15196.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 KR domain WH2 PF02205.20 EGG15197.1 - 5.8e-10 38.7 1.2 1.8e-09 37.1 1.2 1.9 1 0 0 1 1 1 1 WH2 motif SH3_1 PF00018.28 EGG15197.1 - 2.9e-07 30.0 0.0 4.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain CENP-Q PF13094.6 EGG15197.1 - 0.0016 18.7 1.7 0.0026 18.0 1.7 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit SH3_9 PF14604.6 EGG15197.1 - 0.008 16.0 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Spc29 PF17082.5 EGG15197.1 - 0.029 14.2 0.6 0.029 14.2 0.6 1.7 2 0 0 2 2 2 0 Spindle Pole Component 29 Bcr-Abl_Oligo PF09036.10 EGG15197.1 - 0.072 13.1 0.7 0.12 12.3 0.7 1.3 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DUF3251 PF11622.8 EGG15197.1 - 0.077 12.6 1.0 0.12 12.0 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) CCDC-167 PF15188.6 EGG15197.1 - 0.11 12.9 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Spc24 PF08286.11 EGG15197.1 - 0.18 12.0 1.3 0.26 11.5 1.3 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.10 EGG15197.1 - 0.28 11.4 1.6 0.44 10.7 1.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Herpes_UL6 PF01763.16 EGG15197.1 - 0.31 9.5 0.5 0.42 9.1 0.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DivIC PF04977.15 EGG15197.1 - 0.79 9.5 3.9 1.2 8.9 3.9 1.2 1 0 0 1 1 1 0 Septum formation initiator ECH_2 PF16113.5 EGG15198.1 - 1.3e-99 333.8 0.0 1.6e-99 333.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGG15198.1 - 5.1e-26 91.5 0.0 5.2e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase HalOD1 PF18545.1 EGG15198.1 - 0.12 12.7 0.1 26 5.2 0.0 2.5 2 0 0 2 2 2 0 Halobacterial output domain 1 PLN_propep PF16485.5 EGG15198.1 - 2.2 8.1 4.5 11 5.9 0.0 3.1 2 1 0 2 2 2 0 Protealysin propeptide ECH_2 PF16113.5 EGG15199.1 - 4.8e-29 101.9 0.0 1.6e-26 93.6 0.0 4.6 3 3 2 5 5 5 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGG15199.1 - 4.5e-06 26.2 0.0 0.00026 20.4 0.0 3.9 3 2 1 4 4 4 2 Enoyl-CoA hydratase/isomerase Aminotran_3 PF00202.21 EGG15200.1 - 8e-80 268.5 0.0 1e-79 268.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGG15200.1 - 0.0087 15.3 0.0 0.099 11.8 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II ECH_2 PF16113.5 EGG15201.1 - 1.1e-12 48.2 0.0 2.3e-12 47.1 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase PCI PF01399.27 EGG15202.1 - 2.4e-15 56.9 2.6 2.6e-15 56.8 0.1 2.4 3 1 1 4 4 4 1 PCI domain SSFA2_C PF14723.6 EGG15202.1 - 0.09 12.7 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus PP2C PF00481.21 EGG15203.1 - 5e-64 216.4 0.0 7.4e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Symplekin_C PF12295.8 EGG15204.1 - 8.3e-48 162.9 2.0 8.3e-48 162.9 2.0 4.4 4 1 0 4 4 4 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 EGG15204.1 - 2.5e-44 151.6 2.0 2.5e-44 151.6 2.0 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF3453) IMPa_helical PF18642.1 EGG15204.1 - 0.12 12.8 5.8 1 9.8 0.1 2.8 2 0 0 2 2 2 0 Immunomodulating metalloprotease helical domain Ras PF00071.22 EGG15206.1 - 1.8e-16 60.2 0.0 4.5e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG15206.1 - 0.013 15.7 0.5 0.14 12.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 EGG15206.1 - 0.044 14.4 0.0 0.12 13.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ras PF00071.22 EGG15207.1 - 8.1e-18 64.5 2.7 2.2e-17 63.1 0.3 2.5 3 0 0 3 3 3 1 Ras family Roc PF08477.13 EGG15207.1 - 8.3e-05 22.8 0.6 0.0013 19.0 0.6 2.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Paf1 PF03985.13 EGG15208.1 - 0.7 8.8 14.4 1.1 8.2 14.4 1.3 1 0 0 1 1 1 0 Paf1 PA26 PF04636.13 EGG15208.1 - 4.5 6.1 9.1 6.1 5.7 9.1 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hid1 PF12722.7 EGG15208.1 - 9.3 4.2 10.4 11 4.0 10.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TIG PF01833.24 EGG15209.1 - 1.6e-44 149.9 130.8 4.1e-07 30.0 1.3 15.9 15 2 2 17 17 17 14 IPT/TIG domain EGF_2 PF07974.13 EGG15209.1 - 6e-06 26.5 14.3 1.2e-05 25.6 14.3 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG15209.1 - 0.00016 21.6 13.8 0.00041 20.3 13.8 1.8 1 0 0 1 1 1 1 Tenascin EGF domain EGF PF00008.27 EGG15209.1 - 0.001 19.3 7.8 0.0022 18.3 7.8 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 EGG15209.1 - 0.021 15.4 6.1 0.06 14.0 6.1 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF Laminin_EGF PF00053.24 EGG15209.1 - 2.4 8.4 11.0 5.1 7.3 11.0 1.5 1 0 0 1 1 1 0 Laminin EGF domain TIG PF01833.24 EGG15210.1 - 2.7e-48 162.0 172.7 1.3e-06 28.4 2.3 18.3 17 2 2 19 19 19 17 IPT/TIG domain EGF_2 PF07974.13 EGG15210.1 - 2e-05 24.9 14.7 4e-05 23.9 14.7 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG15210.1 - 0.0019 18.2 12.4 0.0019 18.2 12.4 2.5 2 0 0 2 2 2 1 Tenascin EGF domain EGF PF00008.27 EGG15210.1 - 0.0026 18.0 8.5 0.0057 16.9 8.5 1.6 1 0 0 1 1 1 1 EGF-like domain NusG_II PF07009.11 EGG15210.1 - 0.054 13.7 0.1 9.7 6.5 0.0 3.7 3 0 0 3 3 3 0 NusG domain II hEGF PF12661.7 EGG15210.1 - 0.18 12.5 7.3 0.54 11.0 7.3 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF Laminin_EGF PF00053.24 EGG15210.1 - 3.1 8.0 11.4 6.4 7.0 11.4 1.4 1 0 0 1 1 1 0 Laminin EGF domain DSL PF01414.19 EGG15210.1 - 3.6 7.9 7.3 8 6.8 7.3 1.5 1 0 0 1 1 1 0 Delta serrate ligand Ras PF00071.22 EGG15211.1 - 5.1e-16 58.7 0.1 2.8e-13 49.8 0.1 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGG15211.1 - 1.1e-06 28.8 0.1 1.7e-05 25.0 0.1 2.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PsbQ PF05757.11 EGG15211.1 - 0.018 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) NB-ARC PF00931.22 EGG15211.1 - 0.02 14.1 0.1 0.077 12.2 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 EGG15211.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 EGG15211.1 - 0.1 13.2 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) FAM165 PF14981.6 EGG15211.1 - 0.45 10.3 2.1 0.45 10.4 0.2 2.1 2 0 0 2 2 2 0 FAM165 family Ras PF00071.22 EGG15212.1 - 6.5e-16 58.3 0.0 2.2e-13 50.2 0.0 2.5 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGG15212.1 - 5.6e-05 23.3 0.0 0.18 12.1 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 EGG15212.1 - 0.0049 17.4 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TsaE PF02367.17 EGG15212.1 - 0.039 13.9 0.4 0.2 11.7 0.0 2.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TetR_C_37 PF18665.1 EGG15212.1 - 0.1 13.3 0.1 0.1 13.3 0.1 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain MMR_HSR1 PF01926.23 EGG15212.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ras PF00071.22 EGG15213.1 - 1.2e-14 54.2 0.8 2.2e-13 50.1 0.7 2.6 1 1 1 2 2 2 1 Ras family Roc PF08477.13 EGG15213.1 - 1e-05 25.7 0.3 6e-05 23.3 0.3 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 EGG15213.1 - 0.00091 19.8 0.0 0.0023 18.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) MMR_HSR1 PF01926.23 EGG15213.1 - 0.0039 17.2 0.0 0.012 15.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG15213.1 - 0.013 15.4 0.6 3.9 7.4 0.1 3.4 2 1 1 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 EGG15213.1 - 0.043 14.0 0.0 0.3 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGG15213.1 - 0.049 12.8 0.2 0.13 11.4 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain Ank_4 PF13637.6 EGG15213.1 - 0.055 14.1 0.1 0.7 10.5 0.0 2.4 1 1 2 3 3 3 0 Ankyrin repeats (many copies) PduV-EutP PF10662.9 EGG15213.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 EGG15214.1 - 6.7e-07 29.0 0.1 3.7e-06 26.6 0.0 2.2 1 1 1 2 2 2 1 Ras family Bromo_TP_like PF17027.5 EGG15214.1 - 0.031 14.4 1.5 0.053 13.7 0.3 2.0 2 0 0 2 2 2 0 Histone-fold protein MFS_1 PF07690.16 EGG15215.1 - 6.1e-34 117.5 32.5 2.2e-33 115.6 31.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4441 PF14536.6 EGG15215.1 - 0.037 14.2 2.8 0.048 13.9 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) RR_TM4-6 PF06459.12 EGG15215.1 - 0.15 11.9 5.7 0.39 10.5 0.9 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MFS_3 PF05977.13 EGG15215.1 - 1 7.6 6.6 0.15 10.4 1.9 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector DUF3824 PF12868.7 EGG15215.1 - 5.5 7.7 6.9 1.3 9.7 3.7 1.5 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) GRAM PF02893.20 EGG15216.1 - 9.5e-26 89.9 6.1 3.8e-14 52.6 1.5 2.5 2 0 0 2 2 2 2 GRAM domain Vps36_ESCRT-II PF11605.8 EGG15216.1 - 0.26 11.5 4.5 5.4 7.3 0.2 2.7 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 EGG15217.1 - 4.9e-36 123.1 16.3 6.2e-21 74.4 0.1 6.8 5 1 1 6 6 6 5 GRAM domain Glyco_transf_28 PF03033.20 EGG15217.1 - 9.6e-27 93.7 0.0 2e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 EGG15217.1 - 4.8e-12 46.3 0.8 4.8e-12 46.3 0.8 2.4 2 0 0 2 2 2 1 PH domain FYVE PF01363.21 EGG15217.1 - 1.8e-11 44.0 9.2 3.6e-11 43.0 9.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger UDPGT PF00201.18 EGG15217.1 - 2.2e-08 33.4 0.0 5.7e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EGG15217.1 - 2.1e-05 24.6 0.0 5.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PH_TFIIH PF08567.11 EGG15217.1 - 0.00011 22.5 0.0 3.5 8.0 0.0 4.5 4 0 0 4 4 4 1 TFIIH p62 subunit, N-terminal domain FYVE_2 PF02318.16 EGG15217.1 - 1.1 9.5 4.4 2.8 8.2 4.4 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger MFS_5 PF05631.14 EGG15218.1 - 9.6e-90 301.0 14.7 1.4e-89 300.4 14.7 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EGG15218.1 - 4.9e-18 65.2 34.4 1.1e-17 64.0 34.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily HATPase_c PF02518.26 EGG15219.1 - 3.6e-27 95.1 0.0 5.9e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGG15219.1 - 4.3e-22 78.4 0.1 6.4e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain RtcB PF01139.17 EGG15221.1 - 5.8e-152 506.6 0.0 6.7e-152 506.4 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB YchF-GTPase_C PF06071.13 EGG15222.1 - 9.4e-28 96.2 0.2 2.7e-27 94.8 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGG15222.1 - 1.1e-18 67.4 0.0 2.7e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG15222.1 - 2.7e-06 27.0 0.0 8.5e-06 25.4 0.0 1.9 1 0 0 1 1 1 1 Ferrous iron transport protein B LRR_8 PF13855.6 EGG15222.1 - 0.00042 20.0 9.4 0.22 11.3 0.0 5.0 5 0 0 5 5 5 1 Leucine rich repeat LRR_4 PF12799.7 EGG15222.1 - 0.021 15.2 13.2 0.17 12.4 0.1 5.3 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) TIG PF01833.24 EGG15222.1 - 0.029 14.4 0.2 0.029 14.4 0.2 4.0 4 1 0 4 4 4 0 IPT/TIG domain EGF_2 PF07974.13 EGG15222.1 - 0.13 12.6 11.5 0.32 11.4 11.5 1.6 1 0 0 1 1 1 0 EGF-like domain LtuB PF17455.2 EGG15222.1 - 0.15 12.7 0.2 0.47 11.1 0.2 1.8 1 0 0 1 1 1 0 Late transcription unit B hEGF PF12661.7 EGG15222.1 - 1.7 9.4 8.8 4.9 7.9 8.8 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF tRNA_edit PF04073.15 EGG15223.1 - 3.2e-05 24.0 0.0 9.6e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Snapin_Pallidin PF14712.6 EGG15223.1 - 0.21 12.1 2.6 0.14 12.6 0.7 1.7 2 0 0 2 2 2 0 Snapin/Pallidin ANAPC3 PF12895.7 EGG15224.1 - 0.0046 17.1 2.2 0.013 15.7 1.1 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGG15224.1 - 0.0053 16.8 4.3 9.1 6.7 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG15224.1 - 0.065 13.1 5.4 3.5 7.6 1.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Jagunal PF07086.12 EGG15224.1 - 0.089 12.9 2.2 0.11 12.6 1.3 1.6 1 1 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis Bromo_TP_like PF17027.5 EGG15224.1 - 0.84 9.8 7.9 0.085 13.0 2.3 2.2 2 0 0 2 2 2 0 Histone-fold protein MR_MLE_C PF13378.6 EGG15225.1 - 8.9e-54 182.4 0.0 1.5e-53 181.7 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGG15225.1 - 0.00013 22.2 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Na_H_Exchanger PF00999.21 EGG15226.1 - 4.9e-60 203.3 45.3 6.3e-60 203.0 45.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp-Al_Ex PF06826.12 EGG15226.1 - 0.0019 18.0 7.1 0.0019 18.0 7.1 2.7 3 1 0 3 3 3 1 Predicted Permease Membrane Region MRP-L46 PF11788.8 EGG15227.1 - 4.3e-08 33.9 4.7 4.3e-08 33.9 4.7 2.2 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 EGG15227.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 NUDIX domain RD3 PF14473.6 EGG15227.1 - 3.6 7.4 10.0 1.5 8.7 4.6 2.5 3 0 0 3 3 3 0 RD3 protein Tweety PF04906.13 EGG15228.1 - 4.1e-08 32.3 4.9 4.1e-08 32.3 4.9 2.0 2 0 0 2 2 2 1 Tweety MFS_1 PF07690.16 EGG15228.1 - 6.6e-05 22.0 0.8 0.028 13.3 1.2 3.0 3 0 0 3 3 3 1 Major Facilitator Superfamily Connexin PF00029.19 EGG15228.1 - 0.00036 20.4 3.0 0.0047 16.7 0.3 2.3 2 0 0 2 2 2 1 Connexin Pex19 PF04614.12 EGG15228.1 - 0.027 14.3 4.3 0.068 12.9 4.3 1.6 1 0 0 1 1 1 0 Pex19 protein family SARAF PF06682.12 EGG15228.1 - 0.065 12.9 0.6 5.9 6.4 0.0 2.5 2 1 1 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis UPF0542 PF15086.6 EGG15228.1 - 0.092 12.7 0.8 4.3 7.3 0.3 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Calcyon PF06387.11 EGG15228.1 - 0.24 11.4 3.2 2.1 8.3 0.2 3.2 3 0 0 3 3 3 0 D1 dopamine receptor-interacting protein (calcyon) DUF5313 PF17240.2 EGG15228.1 - 0.26 11.7 7.5 2.6 8.5 0.0 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5313) DUF2448 PF10476.9 EGG15228.1 - 0.4 10.5 4.2 1.3 8.9 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function C-terminus (DUF2448) Glycophorin_A PF01102.18 EGG15228.1 - 1.1 9.5 8.9 3 8.1 0.9 3.3 2 2 0 2 2 2 0 Glycophorin A DUF4131 PF13567.6 EGG15228.1 - 1.7 8.2 6.1 4.2 7.0 0.2 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) LMF1 PF06762.14 EGG15228.1 - 3.6 6.6 15.8 3.3 6.7 12.6 2.4 2 1 0 2 2 2 0 Lipase maturation factor Ctr PF04145.15 EGG15228.1 - 3.7 8.2 6.7 10 6.7 0.1 2.6 2 1 0 2 2 2 0 Ctr copper transporter family DUF2207 PF09972.9 EGG15228.1 - 3.9 6.1 20.4 0.68 8.6 3.9 3.8 2 1 1 4 4 4 0 Predicted membrane protein (DUF2207) Pex24p PF06398.11 EGG15228.1 - 5.4 5.9 26.1 0.62 9.0 2.1 3.2 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Alpha-amylase PF00128.24 EGG15229.1 - 6.4e-60 203.5 1.2 9.4e-60 202.9 1.2 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain GHL6 PF14871.6 EGG15229.1 - 0.11 12.6 0.0 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 SIS_2 PF13580.6 EGG15229.1 - 0.13 12.2 0.0 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 SIS domain FNIP PF05725.12 EGG15230.1 - 0.25 11.6 11.5 0.32 11.2 0.0 5.6 7 0 0 7 7 7 0 FNIP Repeat LRR_6 PF13516.6 EGG15230.1 - 3.7 7.8 6.8 35 4.8 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeat CHAT PF12770.7 EGG15231.1 - 3.8e-42 144.7 0.0 4.3e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 CHAT domain Cytochrom_C550 PF14495.6 EGG15231.1 - 0.036 13.8 0.3 0.084 12.6 0.3 1.7 1 0 0 1 1 1 0 Cytochrome c-550 domain Peptidase_C50 PF03568.17 EGG15231.1 - 0.085 12.0 0.5 1.3 8.1 0.1 2.0 2 0 0 2 2 2 0 Peptidase family C50 Ank_2 PF12796.7 EGG15232.1 - 8.9e-15 55.1 4.3 6.7e-05 23.4 0.4 4.3 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG15232.1 - 3.1e-13 49.9 3.1 0.053 14.1 0.3 6.8 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG15232.1 - 1.3e-06 28.6 1.2 33 5.0 0.0 7.5 7 2 2 9 9 9 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG15232.1 - 3.1e-06 27.1 6.5 16 6.5 0.0 8.4 10 0 0 10 10 10 1 Ankyrin repeat Dicty_spore_N PF04562.12 EGG15234.1 - 1.7e-53 180.2 68.1 4.5e-28 98.2 24.3 3.2 3 0 0 3 3 3 2 Dictyostelium spore coat protein, N terminus SRF-TF PF00319.18 EGG15237.1 - 1.5e-16 59.5 0.4 3e-16 58.6 0.4 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Mucin PF01456.17 EGG15237.1 - 0.00061 19.8 14.6 0.00061 19.8 14.6 2.6 2 0 0 2 2 2 1 Mucin-like glycoprotein Beach PF02138.18 EGG15238.1 - 1.2e-122 408.6 0.9 2.6e-122 407.5 0.9 1.6 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EGG15238.1 - 6.1e-13 49.0 10.2 0.0092 16.8 1.9 6.3 5 0 0 5 5 5 4 WD domain, G-beta repeat PH_BEACH PF14844.6 EGG15238.1 - 6.9e-13 48.6 0.0 3.4e-12 46.4 0.0 2.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Arm PF00514.23 EGG15238.1 - 0.00051 20.0 0.5 8.3 6.6 0.0 4.5 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat GRAM PF02893.20 EGG15238.1 - 0.0013 18.5 0.0 0.0068 16.3 0.0 2.3 1 0 0 1 1 1 1 GRAM domain Glyoxalase PF00903.25 EGG15239.1 - 2.2e-22 79.6 0.0 2.6e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGG15239.1 - 9.2e-10 38.8 0.0 7.7e-09 35.8 0.0 1.9 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EGG15239.1 - 2.2e-05 25.2 0.0 3.9e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 EGG15239.1 - 0.0031 17.6 0.0 0.004 17.2 0.0 1.4 1 1 0 1 1 1 1 CppA N-terminal Glyoxalase_2 PF12681.7 EGG15239.1 - 0.0038 17.1 0.0 0.0082 16.1 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EGG15239.1 - 0.093 12.8 0.0 1.7 8.7 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain BB_PF PF18063.1 EGG15240.1 - 1.3e-17 64.1 2.1 6e-10 39.1 0.1 2.5 2 1 1 3 3 3 2 Beta barrel Pore-forming domain Sec1 PF00995.23 EGG15241.1 - 1.2e-111 374.7 18.6 1.6e-111 374.3 18.6 1.2 1 0 0 1 1 1 1 Sec1 family BB_PF PF18063.1 EGG15241.1 - 7e-39 133.6 0.8 2.7e-38 131.7 0.8 2.0 1 1 0 1 1 1 1 Beta barrel Pore-forming domain Occludin_ELL PF07303.13 EGG15241.1 - 0.14 12.9 1.3 27 5.6 0.2 3.4 2 1 0 3 3 3 0 Occludin homology domain COG4 PF08318.12 EGG15242.1 - 1.7e-13 50.4 3.0 1.7e-13 50.4 3.0 2.8 3 0 0 3 3 3 1 COG4 transport protein DIL PF01843.19 EGG15242.1 - 0.0033 17.7 0.4 0.0033 17.7 0.4 3.0 3 0 0 3 3 3 1 DIL domain USP8_dimer PF08969.11 EGG15242.1 - 0.066 13.4 2.8 0.14 12.4 0.5 2.8 2 1 0 2 2 2 0 USP8 dimerisation domain PWWP PF00855.17 EGG15243.1 - 6.5e-12 45.7 0.2 6.5e-12 45.7 0.2 4.0 4 1 1 5 5 5 1 PWWP domain SR-25 PF10500.9 EGG15243.1 - 0.00012 21.8 24.1 0.00012 21.8 24.1 6.8 4 1 3 7 7 7 1 Nuclear RNA-splicing-associated protein Dynactin_p62 PF05502.13 EGG15244.1 - 9.9e-33 113.6 15.7 2.9e-21 75.8 8.7 2.2 2 0 0 2 2 2 2 Dynactin p62 family SR-25 PF10500.9 EGG15244.1 - 0.012 15.2 4.5 0.025 14.2 4.5 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Serglycin PF04360.12 EGG15244.1 - 0.015 15.2 1.1 0.015 15.2 1.1 2.2 1 1 1 2 2 2 0 Serglycin CBFD_NFYB_HMF PF00808.23 EGG15245.1 - 6e-20 71.3 0.1 1.1e-19 70.5 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGG15245.1 - 4.9e-14 52.8 4.6 6.8e-14 52.4 4.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 EGG15245.1 - 0.019 15.1 0.3 0.028 14.6 0.3 1.3 1 0 0 1 1 1 0 CENP-W protein CDC45 PF02724.14 EGG15245.1 - 0.028 12.7 15.0 0.027 12.8 15.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EGG15245.1 - 0.056 12.9 17.7 0.059 12.8 17.7 1.1 1 0 0 1 1 1 0 SDA1 DUF2052 PF09747.9 EGG15245.1 - 0.43 10.7 14.7 0.57 10.3 14.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) YL1 PF05764.13 EGG15245.1 - 0.59 10.2 18.6 0.67 10.0 18.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein PI3K_1B_p101 PF10486.9 EGG15245.1 - 1.3 6.7 6.8 1.4 6.6 6.8 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Mpp10 PF04006.12 EGG15245.1 - 1.3 7.4 21.1 1.6 7.1 21.1 1.1 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 EGG15245.1 - 3.7 5.5 20.2 4 5.4 20.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EGG15245.1 - 5 5.2 22.4 5.8 5.0 22.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 EGG15245.1 - 5.5 6.0 19.5 7.5 5.6 19.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4637 PF15470.6 EGG15245.1 - 6.3 6.5 14.2 9.6 5.9 14.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pox_Ag35 PF03286.14 EGG15245.1 - 8.4 6.1 15.1 13 5.5 15.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.17 EGG15245.1 - 9.5 4.9 8.9 10 4.7 8.9 1.1 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 EGG15246.1 - 1e-16 61.0 5.7 2e-06 28.4 0.5 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat F-box-like PF12937.7 EGG15246.1 - 5.2e-07 29.4 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG15246.1 - 0.00011 21.9 0.1 0.00037 20.3 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EGG15246.1 - 0.019 14.8 0.0 0.079 12.9 0.0 2.1 1 0 0 1 1 1 0 F-box DUF829 PF05705.14 EGG15247.1 - 4.8e-38 131.4 4.1 1e-37 130.4 4.1 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) FSH1 PF03959.13 EGG15247.1 - 0.042 13.5 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) QueF PF14489.6 EGG15247.1 - 0.18 12.0 0.9 4.9 7.4 0.2 2.7 2 1 1 3 3 3 0 QueF-like protein DUF1084 PF06454.11 EGG15248.1 - 1.3e-18 67.3 18.9 2.8e-17 63.0 18.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) DUF2189 PF09955.9 EGG15248.1 - 0.0018 18.5 3.0 0.0018 18.5 3.0 2.8 1 1 2 3 3 3 1 Predicted integral membrane protein (DUF2189) Wzy_C_2 PF11846.8 EGG15248.1 - 0.29 11.1 7.1 0.093 12.6 0.6 2.6 1 1 2 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal MutS_V PF00488.21 EGG15249.1 - 5.2e-81 271.2 0.5 5.2e-81 271.2 0.5 1.8 2 0 0 2 2 2 1 MutS domain V MutS_I PF01624.20 EGG15249.1 - 1.9e-39 134.4 0.1 5.8e-39 132.8 0.1 1.9 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 EGG15249.1 - 5e-36 124.7 5.1 5e-36 124.7 5.1 2.2 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EGG15249.1 - 8.6e-16 58.1 2.2 8.6e-16 58.1 2.2 2.6 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 EGG15249.1 - 5.6e-12 46.1 0.0 4e-11 43.4 0.0 2.5 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.6 EGG15249.1 - 0.004 17.7 0.0 0.004 17.7 0.0 4.9 3 1 0 3 3 2 1 AAA domain T2SSE PF00437.20 EGG15249.1 - 0.052 12.6 0.1 0.12 11.5 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_27 PF13514.6 EGG15249.1 - 0.087 12.4 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGG15249.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DCB PF16213.5 EGG15249.1 - 0.15 11.7 2.0 0.38 10.4 2.0 1.6 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 DUF3246 PF11596.8 EGG15249.1 - 0.31 10.5 7.9 1 8.8 7.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Presenilin PF01080.17 EGG15249.1 - 2.3 6.9 6.5 3.9 6.1 6.5 1.4 1 0 0 1 1 1 0 Presenilin CENP-B_dimeris PF09026.10 EGG15249.1 - 3.5 8.1 15.9 1.1 9.7 3.2 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RRM_2 PF04059.12 EGG15250.1 - 9e-38 128.4 0.7 1.9e-37 127.3 0.7 1.6 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EGG15250.1 - 8.2e-25 86.4 0.7 9.5e-10 38.2 0.0 3.9 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG15250.1 - 2.8e-10 39.8 0.0 4.8e-08 32.6 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG15250.1 - 0.00013 21.8 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 EGG15250.1 - 0.013 15.3 0.0 0.27 11.0 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4523) AAA_12 PF13087.6 EGG15253.1 - 5.3e-62 209.0 2.2 2.6e-61 206.8 0.0 3.0 4 0 0 4 4 4 1 AAA domain AAA_11 PF13086.6 EGG15253.1 - 2.1e-39 135.9 0.8 1.2e-22 81.0 0.1 4.1 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 EGG15253.1 - 7e-10 38.9 0.0 2.1e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG15253.1 - 3.6e-09 37.1 0.0 1.1e-08 35.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGG15253.1 - 9.6e-06 25.5 8.1 0.071 12.8 0.0 4.2 5 0 0 5 5 5 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGG15253.1 - 0.012 15.9 1.8 0.023 15.0 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 EGG15253.1 - 0.04 13.9 0.1 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGG15253.1 - 0.053 13.7 0.5 8.5 6.5 0.1 3.1 2 1 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 EGG15253.1 - 0.06 13.2 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_18 PF13238.6 EGG15253.1 - 0.077 13.5 0.0 0.26 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 EGG15253.1 - 0.15 11.9 2.6 0.2 11.5 0.1 2.4 2 1 0 2 2 2 0 Helicase AAA_25 PF13481.6 EGG15253.1 - 0.16 11.5 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGG15253.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain RNA_helicase PF00910.22 EGG15253.1 - 0.24 11.8 4.2 0.78 10.2 0.0 3.6 4 0 0 4 4 4 0 RNA helicase AAA PF00004.29 EGG15253.1 - 0.3 11.5 2.2 0.58 10.6 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EGG15254.1 - 2.1e-22 79.7 0.0 5.1e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG15254.1 - 3.5e-18 66.0 0.0 2.7e-14 53.4 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EGG15254.1 - 3.2e-08 34.2 0.4 3.2e-08 34.2 0.4 3.0 3 0 0 3 3 3 1 RecQ zinc-binding PapG_N PF03627.13 EGG15254.1 - 0.019 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 PapG carbohydrate binding domain SPT6_acidic PF14632.6 EGG15254.1 - 0.78 10.4 21.3 0.23 12.1 17.4 2.2 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Aldedh PF00171.22 EGG15255.1 - 1.4e-129 432.6 0.1 1.7e-129 432.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAM25 PF15825.5 EGG15255.1 - 0.057 13.8 0.4 0.23 11.8 0.4 2.1 1 0 0 1 1 1 0 FAM25 family BB_PF PF18063.1 EGG15256.1 - 1.7e-15 57.2 5.3 2.2e-15 56.8 5.3 1.1 1 0 0 1 1 1 1 Beta barrel Pore-forming domain Phytochelatin PF05023.14 EGG15257.1 - 4.4e-89 297.3 0.0 6.3e-89 296.8 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 EGG15257.1 - 0.0053 17.3 2.5 0.051 14.1 0.2 3.2 3 1 0 3 3 3 1 Peptidase_C39 like family Pan3_PK PF18101.1 EGG15257.1 - 0.062 13.3 0.7 0.13 12.2 0.6 1.6 1 1 0 1 1 1 0 Pan3 Pseudokinase domain Peptidase_M41 PF01434.18 EGG15258.1 - 1.9e-55 187.7 2.2 1.9e-55 187.7 2.2 2.0 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 EGG15258.1 - 7.9e-44 149.3 0.9 6.7e-42 143.0 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG15258.1 - 9.1e-08 31.8 0.0 3.4e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain TIP49 PF06068.13 EGG15258.1 - 2.7e-05 23.5 0.1 7.4e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 EGG15258.1 - 0.00011 22.4 0.0 0.0089 16.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGG15258.1 - 0.00012 22.5 0.1 0.0039 17.6 0.0 2.9 3 1 1 4 4 2 1 AAA ATPase domain AAA_2 PF07724.14 EGG15258.1 - 0.00012 22.2 1.7 0.0012 19.0 0.0 3.2 4 0 0 4 4 3 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EGG15258.1 - 0.00065 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 EGG15258.1 - 0.00067 19.7 0.2 0.0031 17.5 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGG15258.1 - 0.00097 19.2 0.1 0.042 13.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EGG15258.1 - 0.0012 18.6 0.0 0.0037 17.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EGG15258.1 - 0.0032 16.9 0.1 0.012 15.0 0.1 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EGG15258.1 - 0.0034 16.7 2.7 0.034 13.4 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.6 EGG15258.1 - 0.01 16.4 0.0 0.01 16.4 0.0 3.5 4 1 0 4 4 3 0 AAA domain Sigma54_activat PF00158.26 EGG15258.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 EGG15258.1 - 0.012 15.9 0.0 0.044 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGG15258.1 - 0.027 14.6 0.0 0.027 14.6 0.0 2.6 4 0 0 4 4 3 0 AAA domain AAA_24 PF13479.6 EGG15258.1 - 0.049 13.4 1.6 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGG15258.1 - 0.087 13.3 2.2 0.4 11.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 EGG15258.1 - 0.13 11.8 0.0 0.7 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGG15258.1 - 0.19 12.1 2.1 0.72 10.3 0.0 2.9 3 0 0 3 3 2 0 RNA helicase Pex14_N PF04695.13 EGG15258.1 - 0.22 12.2 21.3 1.9 9.1 0.3 2.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ABC_tran PF00005.27 EGG15258.1 - 0.24 11.9 0.0 0.24 11.9 0.0 4.0 4 0 0 4 4 3 0 ABC transporter ERAP1_C PF11838.8 EGG15261.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Myb_DNA-binding PF00249.31 EGG15261.1 - 0.19 11.9 0.0 0.55 10.5 0.0 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain Yippee-Mis18 PF03226.14 EGG15263.1 - 3.5e-15 56.1 1.1 3.5e-15 56.1 1.1 2.7 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Pro_CA PF00484.19 EGG15263.1 - 0.0048 17.2 0.0 0.0048 17.2 0.0 3.5 4 0 0 4 4 4 1 Carbonic anhydrase CDC45 PF02724.14 EGG15263.1 - 0.081 11.2 20.8 0.003 15.9 14.1 1.8 2 0 0 2 2 2 0 CDC45-like protein YL1 PF05764.13 EGG15263.1 - 0.38 10.8 33.0 0.014 15.5 17.9 2.8 3 0 0 3 3 3 0 YL1 nuclear protein Zip PF02535.22 EGG15263.1 - 2.5 7.2 5.2 6.3 5.9 5.2 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGG15263.1 - 7.9 5.1 21.0 1.2 7.8 15.9 1.9 2 0 0 2 2 2 0 Presenilin CRAL_TRIO_2 PF13716.6 EGG15264.1 - 1.3e-19 70.8 1.7 2.5e-19 69.8 1.7 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.21 EGG15264.1 - 1.2e-15 57.6 0.0 2.1e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Macro domain CRAL_TRIO PF00650.20 EGG15264.1 - 0.0005 19.8 0.9 0.0011 18.7 0.9 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain Epimerase PF01370.21 EGG15265.1 - 9.9e-14 51.4 0.0 2.4e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1731 PF08338.11 EGG15265.1 - 4.8e-12 45.5 0.0 9.1e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) RmlD_sub_bind PF04321.17 EGG15265.1 - 6.1e-05 22.3 0.0 9.1e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGG15265.1 - 0.00013 21.5 0.0 0.0017 17.9 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGG15265.1 - 0.0066 15.7 0.0 0.047 12.8 0.0 2.0 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EGG15265.1 - 0.052 12.5 0.0 0.099 11.6 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EGG15265.1 - 0.2 11.5 0.0 0.6 10.0 0.0 1.6 1 1 1 2 2 2 0 KR domain Prefoldin PF02996.17 EGG15267.1 - 1.7e-24 86.0 1.8 1.7e-24 86.0 1.8 1.8 1 1 1 2 2 2 1 Prefoldin subunit TMF_TATA_bd PF12325.8 EGG15267.1 - 0.024 14.8 2.3 0.029 14.6 0.7 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SIMPL PF04402.14 EGG15267.1 - 0.098 13.1 0.3 0.098 13.1 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF541) Sec2p PF06428.11 EGG15267.1 - 0.11 12.4 3.7 0.91 9.5 1.6 2.6 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Syntaxin-6_N PF09177.11 EGG15267.1 - 0.17 12.5 4.1 7.4 7.2 0.1 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Las1 PF04031.13 EGG15269.1 - 3.2e-35 121.5 0.9 8.2e-35 120.2 0.2 2.1 2 0 0 2 2 2 1 Las1-like DUF2258 PF10015.9 EGG15269.1 - 0.34 11.1 4.6 9.2 6.5 0.3 3.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) ABC_tran PF00005.27 EGG15270.1 - 2e-44 151.4 0.0 7.3e-22 78.4 0.0 2.5 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGG15270.1 - 1.4e-20 73.1 2.1 1.4e-20 73.1 2.1 2.1 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 EGG15270.1 - 1.6e-14 54.4 0.2 0.0015 18.4 0.1 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGG15270.1 - 3.3e-09 37.0 0.0 0.0032 17.2 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EGG15270.1 - 3.3e-08 33.2 0.0 0.0014 18.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EGG15270.1 - 2.6e-07 30.3 1.5 0.039 13.4 0.1 4.1 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGG15270.1 - 3.3e-07 31.0 10.1 0.0026 18.3 0.0 4.1 4 1 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 EGG15270.1 - 6.1e-07 29.5 0.9 0.0013 18.6 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_28 PF13521.6 EGG15270.1 - 4.9e-06 26.9 0.0 0.04 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGG15270.1 - 5.2e-06 26.8 0.0 0.0041 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGG15270.1 - 6.4e-06 26.2 0.0 0.2 11.7 0.0 3.3 2 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EGG15270.1 - 7.9e-06 26.1 0.0 0.023 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGG15270.1 - 2.1e-05 25.0 0.0 0.037 14.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EGG15270.1 - 0.00012 22.1 2.4 0.3 11.0 0.1 3.1 2 2 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 EGG15270.1 - 0.00015 21.8 0.0 0.038 14.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGG15270.1 - 0.00016 22.1 0.0 0.26 11.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 EGG15270.1 - 0.0004 20.4 0.0 0.51 10.2 0.0 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_24 PF13479.6 EGG15270.1 - 0.0005 19.8 0.0 0.76 9.5 0.0 2.7 3 0 0 3 3 3 2 AAA domain G-alpha PF00503.20 EGG15270.1 - 0.00082 18.6 0.7 0.33 10.1 0.2 2.6 2 1 1 3 3 3 1 G-protein alpha subunit AAA_7 PF12775.7 EGG15270.1 - 0.0015 18.0 0.0 0.47 9.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 EGG15270.1 - 0.0019 18.6 0.0 0.27 11.7 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EGG15270.1 - 0.0022 18.1 1.7 0.24 11.5 0.0 3.4 2 1 1 3 3 3 1 Helicase HerA, central domain TsaE PF02367.17 EGG15270.1 - 0.0026 17.8 0.2 0.15 12.0 0.0 2.7 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EGG15270.1 - 0.0026 17.4 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EGG15270.1 - 0.0033 17.0 0.0 1.2 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EGG15270.1 - 0.0053 15.8 0.0 1.6 7.6 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2813 PF11398.8 EGG15270.1 - 0.006 15.9 0.0 0.77 9.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) Dynamin_N PF00350.23 EGG15270.1 - 0.0065 16.5 1.1 4.9 7.2 0.0 3.6 2 1 1 3 3 3 0 Dynamin family AAA_18 PF13238.6 EGG15270.1 - 0.0078 16.8 0.0 2.4 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain MukB PF04310.12 EGG15270.1 - 0.015 15.1 0.0 0.67 9.7 0.0 2.7 3 0 0 3 3 2 0 MukB N-terminal dNK PF01712.19 EGG15270.1 - 0.024 14.5 0.0 0.8 9.5 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase NB-ARC PF00931.22 EGG15270.1 - 0.025 13.8 0.0 0.75 8.9 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain AAA_5 PF07728.14 EGG15270.1 - 0.037 14.0 0.6 3 7.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EGG15270.1 - 0.04 13.6 0.0 0.54 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGG15270.1 - 0.04 14.3 0.0 4.3 7.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGG15270.1 - 0.059 13.3 1.5 12 5.7 0.0 3.0 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 EGG15270.1 - 0.066 13.0 0.3 22 4.8 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 EGG15270.1 - 0.077 12.1 0.2 2.8 7.0 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF815) DUF3584 PF12128.8 EGG15270.1 - 0.084 10.4 0.3 0.43 8.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) PRK PF00485.18 EGG15270.1 - 0.085 12.6 0.0 7.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 EGG15270.1 - 0.086 12.7 0.3 1.2 9.0 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 EGG15270.1 - 0.088 13.0 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DHC_N1 PF08385.12 EGG15270.1 - 0.094 11.3 0.6 0.61 8.6 0.1 2.2 2 1 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 NTPase_1 PF03266.15 EGG15270.1 - 0.11 12.5 0.1 1.9 8.4 0.1 2.6 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 EGG15270.1 - 0.14 11.5 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 EGG15270.1 - 0.15 11.4 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 EGG15270.1 - 1.3 8.6 3.4 1.8 8.1 0.1 2.5 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_RNA_Pol_19 PF05320.12 EGG15271.1 - 0.063 13.3 0.4 1.1 9.2 0.0 2.5 2 1 1 3 3 3 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit NanE PF04131.14 EGG15271.1 - 0.18 11.0 0.2 3.7 6.7 0.0 2.1 1 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Peptidase_S9 PF00326.21 EGG15274.1 - 5.8e-05 22.7 0.3 0.0001 21.9 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGG15274.1 - 0.0085 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EGG15274.1 - 0.015 14.9 0.0 0.015 14.9 0.0 1.9 2 0 0 2 2 2 0 Putative esterase M_domain PF12938.7 EGG15274.1 - 0.6 9.9 14.1 1.3 8.7 14.1 1.5 1 0 0 1 1 1 0 M domain of GW182 Rtf2 PF04641.12 EGG15275.1 - 8.4e-55 186.0 21.5 2.8e-54 184.2 21.5 1.7 1 1 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 EGG15275.1 - 0.021 14.7 1.1 0.081 12.8 0.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Neur_chan_memb PF02932.16 EGG15275.1 - 0.29 11.2 8.4 0.33 11.0 8.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 EGG15275.1 - 1.1 7.4 17.8 1.7 6.9 17.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 EGG15275.1 - 1.5 6.8 19.9 1.9 6.5 19.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mucin PF01456.17 EGG15275.1 - 2.6 8.0 21.0 4 7.4 21.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein PA26 PF04636.13 EGG15275.1 - 3.7 6.4 13.8 5.6 5.8 13.8 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) LYRIC PF15686.5 EGG15275.1 - 5.8 6.4 31.8 9.6 5.6 31.8 1.3 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF4718 PF15842.5 EGG15275.1 - 6.7 6.5 12.1 14 5.4 12.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) DUF2052 PF09747.9 EGG15275.1 - 7.1 6.7 23.9 11 6.0 23.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) LRR_4 PF12799.7 EGG15276.1 - 1.2e-08 35.1 28.2 0.0044 17.4 0.4 8.2 9 1 0 9 9 9 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG15276.1 - 2.2e-06 27.3 13.6 0.0023 17.7 0.3 6.3 5 2 0 6 6 6 2 Leucine rich repeat DUF1506 PF07405.11 EGG15276.1 - 0.0025 18.0 0.6 0.014 15.5 0.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1506) Vault_3 PF17795.1 EGG15276.1 - 0.21 11.7 0.8 7.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Major Vault Protein Repeat domain Ank_2 PF12796.7 EGG15278.1 - 3.2e-08 34.0 2.4 0.0017 18.9 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG15278.1 - 6.9e-06 26.5 0.1 0.034 14.7 0.0 3.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG15278.1 - 2.1e-05 24.7 0.0 0.15 12.5 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) EcoR124_C PF12008.8 EGG15278.1 - 0.0035 17.0 0.8 0.025 14.2 0.8 2.0 1 1 0 1 1 1 1 Type I restriction and modification enzyme - subunit R C terminal Ank_3 PF13606.6 EGG15278.1 - 0.0069 16.8 0.3 25 5.9 0.0 4.2 3 2 1 4 4 4 0 Ankyrin repeat DUF5049 PF16468.5 EGG15278.1 - 0.009 15.9 0.7 4.4 7.3 0.0 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF5049) TubC_N PF18563.1 EGG15278.1 - 0.046 13.7 0.2 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 TubC N-terminal docking domain Ank PF00023.30 EGG15278.1 - 0.11 12.9 0.0 11 6.7 0.0 3.6 2 2 0 2 2 2 0 Ankyrin repeat Peptidase_C1 PF00112.23 EGG15279.1 - 2.7e-70 236.9 5.3 3.4e-70 236.5 5.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG15279.1 - 3e-12 46.8 2.3 5.2e-12 46.0 2.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGG15279.1 - 0.00017 20.5 7.0 0.015 14.1 0.1 2.9 2 1 0 3 3 3 2 Peptidase C1-like family DUF3756 PF12581.8 EGG15279.1 - 2.2 8.3 4.7 2.6 8.0 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3756) CIA30 PF08547.12 EGG15280.1 - 3.7e-24 85.6 0.0 6.1e-23 81.6 0.0 2.0 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 EGG15280.1 - 7.4e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) SGBP_B_XBD PF18329.1 EGG15280.1 - 0.00019 21.5 4.6 0.015 15.3 0.0 2.3 1 1 1 2 2 2 2 Surface glycan-binding protein B xyloglucan binding domain RRM_1 PF00076.22 EGG15281.1 - 2.3e-16 59.4 0.0 4.5e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG15281.1 - 3.1e-06 27.2 4.2 5.8e-06 26.3 0.1 2.7 2 0 0 2 2 2 1 RNA recognition motif SelP_N PF04592.14 EGG15281.1 - 9.2 5.6 23.9 1 8.7 5.8 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region putAbiC PF16872.5 EGG15282.1 - 2.7 8.7 6.2 0.71 10.6 0.4 2.7 2 1 0 2 2 2 0 Putative phage abortive infection protein TIG PF01833.24 EGG15284.1 - 1.1e-18 67.0 69.0 3.9e-09 36.5 3.4 8.8 9 0 0 9 9 9 7 IPT/TIG domain DUF4448 PF14610.6 EGG15284.1 - 0.01 15.6 0.1 0.041 13.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) T2SSF PF00482.23 EGG15284.1 - 0.16 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Myb_DNA-bind_6 PF13921.6 EGG15285.1 - 2.2e-05 24.6 2.4 5.4e-05 23.4 2.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGG15285.1 - 0.0023 18.1 0.6 0.0061 16.7 0.6 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain RR_TM4-6 PF06459.12 EGG15286.1 - 0.1 12.4 7.6 0.14 11.9 7.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.15 EGG15286.1 - 0.47 9.3 4.1 0.63 8.9 4.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 EGG15286.1 - 2.7 6.7 6.5 3.5 6.3 6.5 1.1 1 0 0 1 1 1 0 Presenilin CS PF04969.16 EGG15287.1 - 3e-16 60.2 0.2 8.1e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 CS domain Complex1_LYR PF05347.15 EGG15287.1 - 0.00022 21.2 0.0 0.00044 20.2 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) YidC_periplas PF14849.6 EGG15287.1 - 0.025 14.5 0.4 0.035 14.0 0.4 1.3 1 0 0 1 1 1 0 YidC periplasmic domain Epimerase PF01370.21 EGG15288.1 - 3.9e-51 173.8 0.0 5.2e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG15288.1 - 6.1e-15 55.4 0.1 9.7e-15 54.8 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGG15288.1 - 1.6e-05 24.2 3.3 0.0001 21.6 0.0 2.6 2 2 1 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGG15288.1 - 0.00014 21.1 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain RPN7 PF10602.9 EGG15289.1 - 3.7e-58 196.1 1.6 5.8e-58 195.4 1.6 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGG15289.1 - 4.6e-17 62.4 0.3 1.6e-16 60.7 0.0 2.1 2 0 0 2 2 2 1 PCI domain MRP-L46 PF11788.8 EGG15289.1 - 0.007 17.1 2.0 0.007 17.1 2.0 1.9 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 TPR_7 PF13176.6 EGG15289.1 - 0.071 13.2 0.0 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat S6PP_C PF08472.10 EGG15290.1 - 0.0058 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 Sucrose-6-phosphate phosphohydrolase C-terminal Ank_4 PF13637.6 EGG15291.1 - 1.1e-07 32.3 0.0 0.0032 18.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG15291.1 - 1.8e-06 28.4 0.0 0.009 16.6 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGG15291.1 - 2.2e-06 27.8 0.0 1.3e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 EGG15291.1 - 1.7e-05 25.0 0.0 0.024 14.9 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG15291.1 - 0.001 19.4 0.1 4 8.3 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat KxDL PF10241.9 EGG15292.1 - 3.7e-23 81.6 3.6 3.7e-23 81.6 3.6 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein Cyclin_C PF02984.19 EGG15292.1 - 0.038 14.1 1.6 0.06 13.4 1.6 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain TbpB_A PF17484.2 EGG15292.1 - 0.091 13.5 5.4 0.14 12.9 5.4 1.2 1 0 0 1 1 1 0 N-Lobe handle Tf-binding protein B Mucin PF01456.17 EGG15292.1 - 0.16 12.0 6.6 0.22 11.5 6.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Holin_BhlA PF10960.8 EGG15292.1 - 2.9 7.9 6.7 0.26 11.3 1.5 1.9 2 0 0 2 2 2 0 BhlA holin family DUF1043 PF06295.12 EGG15292.1 - 5.5 7.0 12.7 0.074 13.1 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Plant_tran PF04827.14 EGG15293.1 - 0.0049 16.5 0.1 0.0089 15.6 0.1 1.4 1 0 0 1 1 1 1 Plant transposon protein Ank_2 PF12796.7 EGG15293.1 - 0.015 15.8 0.3 27 5.5 0.0 3.9 3 1 2 5 5 5 0 Ankyrin repeats (3 copies) CPSF100_C PF13299.6 EGG15295.1 - 0.24 11.6 1.1 0.44 10.7 1.1 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 EGG15295.1 - 1.4 7.6 5.7 2.1 7.0 5.7 1.2 1 0 0 1 1 1 0 Presenilin PRC2_HTH_1 PF18118.1 EGG15295.1 - 2 9.3 10.7 0.72 10.7 7.3 2.0 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Gti1_Pac2 PF09729.9 EGG15295.1 - 9.4 6.3 11.3 21 5.2 11.3 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2443 PF10398.9 EGG15296.1 - 0.091 12.8 0.3 2.6 8.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) DUF2560 PF10834.8 EGG15296.1 - 0.11 12.7 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) Styelin PF17562.2 EGG15297.1 - 0.04 14.3 4.3 0.049 14.0 1.5 2.2 1 1 1 2 2 2 0 Styelin DUF3450 PF11932.8 EGG15297.1 - 1.6 8.0 12.9 1.8 7.8 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2443 PF10398.9 EGG15298.1 - 0.35 11.0 2.8 6.6 6.9 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2443) Exo5 PF09810.9 EGG15299.1 - 0.011 15.2 0.8 0.011 15.2 0.8 1.5 2 0 0 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease PRC2_HTH_1 PF18118.1 EGG15299.1 - 0.19 12.5 6.3 0.37 11.6 5.3 2.0 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain GCD14 PF08704.10 EGG15299.1 - 0.32 10.6 3.1 0.63 9.7 3.1 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Cupin_8 PF13621.6 EGG15302.1 - 5.3e-18 65.7 0.0 1.3e-17 64.4 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EGG15302.1 - 1.5e-16 60.9 0.2 3e-15 56.6 0.0 3.0 2 1 0 2 2 2 1 JmjC domain, hydroxylase F-box PF00646.33 EGG15302.1 - 0.00069 19.4 0.3 0.0019 18.0 0.0 2.0 2 0 0 2 2 2 1 F-box domain APH PF01636.23 EGG15302.1 - 0.0011 19.0 0.1 0.64 9.9 0.0 3.0 3 0 0 3 3 3 2 Phosphotransferase enzyme family F-box-like PF12937.7 EGG15302.1 - 0.0021 17.9 0.0 0.0065 16.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like DUF4604 PF15377.6 EGG15302.1 - 9.3 6.6 6.5 1.2 9.5 1.3 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) Pkinase PF00069.25 EGG15303.1 - 2.6e-63 213.8 0.0 4.7e-63 213.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG15303.1 - 2.1e-40 138.7 0.1 5.7e-40 137.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG15303.1 - 1.4e-07 30.8 4.1 1.2e-06 27.8 4.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGG15303.1 - 8.1e-06 24.9 0.4 5.5e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Spore_YhcN_YlaJ PF09580.10 EGG15303.1 - 0.33 11.0 11.3 0.54 10.3 11.3 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) zf-CCCH_2 PF14608.6 EGG15304.1 - 7.6e-25 86.5 72.2 1e-05 25.8 1.9 7.4 7 0 0 7 7 7 7 RNA-binding, Nab2-type zinc finger PWI PF01480.17 EGG15304.1 - 0.00057 20.1 0.2 0.0011 19.2 0.2 1.4 1 0 0 1 1 1 1 PWI domain Nab2p_Zf1 PF18260.1 EGG15304.1 - 0.0068 16.3 0.9 0.0068 16.3 0.9 3.6 4 0 0 4 4 4 1 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 zf_CCCH_4 PF18345.1 EGG15304.1 - 0.027 14.5 0.3 0.027 14.5 0.3 9.3 10 2 2 12 12 12 0 Zinc finger domain zf-CCCH PF00642.24 EGG15304.1 - 0.036 14.0 0.3 0.036 14.0 0.3 9.4 9 3 0 9 9 9 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Secapin PF17521.2 EGG15304.1 - 0.045 13.5 0.3 0.84 9.5 0.0 2.8 2 0 0 2 2 2 0 Honey bee peptides zf-CCCH_4 PF18044.1 EGG15304.1 - 0.074 12.9 0.4 0.074 12.9 0.4 8.0 7 2 0 7 7 7 0 CCCH-type zinc finger NADH-u_ox-rdase PF10785.9 EGG15305.1 - 1.7e-13 51.0 0.6 2.4e-13 50.6 0.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF5316 PF17247.2 EGG15305.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5316) Adaptin_binding PF10199.9 EGG15306.1 - 4.6e-16 59.5 5.6 4.6e-16 59.5 5.6 1.7 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Ras PF00071.22 EGG15306.1 - 0.0057 16.3 0.4 0.011 15.4 0.1 1.7 2 0 0 2 2 2 1 Ras family PNGaseA PF12222.8 EGG15306.1 - 0.22 10.4 3.3 0.33 9.7 3.3 1.2 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A CS PF04969.16 EGG15307.1 - 1.4e-07 32.5 0.3 2.2e-07 31.8 0.3 1.3 1 0 0 1 1 1 1 CS domain Myb_DNA-binding PF00249.31 EGG15308.1 - 9e-10 38.6 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain 4F5 PF04419.14 EGG15309.1 - 6.5e-05 23.7 6.1 6.5e-05 23.7 6.1 3.0 1 1 1 2 2 2 1 4F5 protein family CH PF00307.31 EGG15310.1 - 8.7e-17 61.3 0.0 2.9e-16 59.6 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGG15310.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain Yip1 PF04893.17 EGG15312.1 - 1.6e-08 34.5 9.6 2.1e-08 34.1 9.6 1.2 1 0 0 1 1 1 1 Yip1 domain Lactamase_B_6 PF16661.5 EGG15314.1 - 7.7e-59 198.4 0.0 1.9e-58 197.1 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EGG15314.1 - 6.1e-26 91.6 8.0 3.7e-25 89.1 0.0 3.2 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EGG15314.1 - 2.1e-18 66.6 0.2 1.6e-17 63.8 0.0 2.5 3 0 0 3 3 3 1 Beta-Casp domain RMMBL PF07521.12 EGG15314.1 - 5.1e-07 29.5 0.0 1.4e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EGG15314.1 - 3e-05 24.1 0.0 0.0001 22.4 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily ING PF12998.7 EGG15316.1 - 5.4e-19 68.7 2.8 9.7e-19 67.8 2.8 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGG15316.1 - 5.5e-07 29.4 7.3 9.2e-07 28.7 7.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EGG15316.1 - 0.011 16.0 0.9 0.025 14.8 0.9 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prominin PF05478.11 EGG15316.1 - 0.013 13.5 3.0 0.017 13.1 3.0 1.1 1 0 0 1 1 1 0 Prominin RRN3 PF05327.11 EGG15316.1 - 0.049 12.2 3.2 0.054 12.0 3.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SOGA PF11365.8 EGG15316.1 - 0.055 14.6 3.8 0.065 14.4 2.8 1.6 2 0 0 2 2 2 0 Protein SOGA Spc7 PF08317.11 EGG15316.1 - 0.071 12.0 7.6 0.11 11.4 7.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup88 PF10168.9 EGG15316.1 - 0.3 8.9 6.2 0.41 8.4 6.2 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF1451 PF07295.11 EGG15316.1 - 1.7 8.6 6.7 0.98 9.4 3.6 2.1 3 0 0 3 3 3 0 Zinc-ribbon containing domain Acetyltransf_3 PF13302.7 EGG15317.1 - 6.8e-23 81.9 0.0 9.2e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG15317.1 - 0.00083 19.6 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DNase_II PF03265.15 EGG15319.1 - 6.5e-12 45.4 2.4 3.6e-06 26.5 0.1 3.3 3 0 0 3 3 3 3 Deoxyribonuclease II FNIP PF05725.12 EGG15319.1 - 0.34 11.1 2.6 1.2 9.3 0.1 3.2 4 0 0 4 4 4 0 FNIP Repeat WH1 PF00568.23 EGG15320.1 - 0.085 12.8 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 WH1 domain OmdA PF13376.6 EGG15321.1 - 5.9e-13 48.6 0.3 1.2e-12 47.6 0.3 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated FAM60A PF15396.6 EGG15321.1 - 9 6.2 12.9 1 9.3 6.6 2.2 2 0 0 2 2 2 0 Protein Family FAM60A TPR_1 PF00515.28 EGG15322.1 - 1.2e-11 43.9 0.4 5.1e-05 22.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG15322.1 - 2.3e-09 36.7 0.2 0.0052 16.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat SET PF00856.28 EGG15322.1 - 3.4e-07 30.8 2.1 1.7e-06 28.5 2.1 2.2 1 1 0 1 1 1 1 SET domain TPR_16 PF13432.6 EGG15322.1 - 1.4e-06 28.8 0.2 0.0008 20.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-MYND PF01753.18 EGG15322.1 - 1e-05 25.5 11.1 1e-05 25.5 11.1 2.5 2 1 0 2 2 2 1 MYND finger TPR_11 PF13414.6 EGG15322.1 - 0.00012 21.7 2.1 0.00055 19.6 0.1 2.9 1 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 EGG15322.1 - 0.00021 21.2 0.8 0.41 11.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG15322.1 - 0.00051 20.2 2.6 0.41 11.1 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG15322.1 - 0.011 16.0 0.6 0.032 14.4 0.6 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 EppA_BapA PF07268.11 EGG15322.1 - 0.014 15.4 1.5 0.02 14.8 0.6 1.8 2 0 0 2 2 2 0 Exported protein precursor (EppA/BapA) TPR_19 PF14559.6 EGG15322.1 - 0.019 15.5 0.0 9.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG15322.1 - 0.041 14.7 0.1 5.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EGG15322.1 - 0.15 12.1 0.5 6.7 6.9 0.0 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ATE_N PF04376.13 EGG15322.1 - 0.24 11.8 0.0 0.24 11.8 0.0 4.1 5 0 0 5 5 4 0 Arginine-tRNA-protein transferase, N terminus RhoGEF PF00621.20 EGG15323.1 - 1.7e-40 139.2 6.8 1.7e-40 139.2 6.8 4.7 4 1 1 5 5 5 1 RhoGEF domain PH PF00169.29 EGG15323.1 - 0.004 17.6 0.5 0.012 16.1 0.5 1.9 1 0 0 1 1 1 1 PH domain Adenine_glyco PF03352.13 EGG15324.1 - 2.1e-49 167.7 11.7 1.9e-44 151.5 0.4 2.8 2 1 1 3 3 3 2 Methyladenine glycosylase BUD22 PF09073.10 EGG15324.1 - 0.011 15.1 11.7 0.012 14.9 11.7 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EGG15324.1 - 0.04 12.2 8.5 0.038 12.3 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 EGG15324.1 - 0.26 10.7 14.3 0.36 10.2 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RPN2_C PF18004.1 EGG15324.1 - 0.62 10.0 13.5 0.46 10.4 11.7 1.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Zip PF02535.22 EGG15324.1 - 0.62 9.2 4.5 0.67 9.1 4.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 EGG15324.1 - 0.71 8.0 17.7 0.88 7.7 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family VIR_N PF15912.5 EGG15324.1 - 1.4 8.4 13.0 2.1 7.9 13.0 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Sporozoite_P67 PF05642.11 EGG15324.1 - 1.7 6.7 13.5 2.2 6.3 13.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TRAP_alpha PF03896.16 EGG15324.1 - 5.4 6.1 10.4 8.8 5.4 10.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 EGG15324.1 - 6.8 5.3 11.2 8.3 5.1 11.2 1.1 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 EGG15324.1 - 8.5 5.7 15.4 16 4.8 15.4 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 EGG15324.1 - 9.4 5.5 15.9 15 4.8 15.9 1.2 1 0 0 1 1 1 0 NOA36 protein RR_TM4-6 PF06459.12 EGG15324.1 - 9.8 5.9 15.3 13 5.5 15.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2157 PF09925.9 EGG15325.1 - 0.028 14.2 15.5 1.1 9.0 0.3 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) FANCI_S3 PF14677.6 EGG15326.1 - 7.5e-05 22.5 0.5 0.053 13.2 0.0 3.6 3 0 0 3 3 3 2 FANCI solenoid 3 DUF565 PF04483.12 EGG15326.1 - 0.083 13.4 0.2 0.33 11.5 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF565) HEAT_2 PF13646.6 EGG15326.1 - 0.13 12.7 0.0 1.1 9.7 0.0 2.6 3 0 0 3 3 3 0 HEAT repeats Colicin_K PF17500.2 EGG15327.1 - 0.027 15.0 0.6 0.096 13.3 0.2 2.0 1 1 1 2 2 2 0 Colicin-K Invas_SpaK PF03519.14 EGG15327.1 - 0.039 14.0 0.6 0.065 13.3 0.6 1.5 1 0 0 1 1 1 0 Invasion protein B family SPC25 PF06703.11 EGG15328.1 - 0.25 11.1 11.0 0.56 10.0 6.0 2.7 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2627 PF11118.8 EGG15328.1 - 0.98 10.0 10.1 0.44 11.1 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) Miga PF10265.9 EGG15328.1 - 1.6 7.6 5.7 2.2 7.2 5.7 1.1 1 0 0 1 1 1 0 Mitoguardin SelK_SelG PF10961.8 EGG15330.1 - 1.3e-09 38.5 0.1 1.5e-09 38.3 0.1 1.0 1 0 0 1 1 1 1 Selenoprotein SelK_SelG Peptidase_C1 PF00112.23 EGG15332.1 - 3.8e-11 43.5 2.8 6.7e-09 36.2 0.5 2.2 1 1 1 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG15332.1 - 0.1 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) SPX PF03105.19 EGG15333.1 - 3.5e-18 66.7 14.8 1.1e-08 35.5 4.8 3.2 1 1 2 3 3 3 3 SPX domain Nsp1_C PF05064.13 EGG15333.1 - 0.028 14.2 0.4 0.046 13.5 0.0 1.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF4937 PF16291.5 EGG15333.1 - 0.041 14.1 0.1 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4937 Ras PF00071.22 EGG15334.1 - 7.7e-33 113.4 0.0 1.8e-32 112.2 0.0 1.7 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG15334.1 - 2.8e-19 69.5 0.0 7.3e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG15334.1 - 1e-10 41.4 0.0 2.7e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_6 PF13516.6 EGG15334.1 - 6.5e-06 25.8 26.7 0.21 11.8 0.1 7.1 7 0 0 7 7 7 4 Leucine Rich repeat Gtr1_RagA PF04670.12 EGG15334.1 - 0.0011 18.4 0.0 0.0029 17.0 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG15334.1 - 0.0069 16.5 0.0 0.024 14.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EGG15334.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain LRR_1 PF00560.33 EGG15334.1 - 0.52 11.1 16.0 31 5.6 0.4 6.4 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 EGG15334.1 - 3 8.4 31.4 0.6 10.6 0.7 5.3 1 1 5 6 6 6 0 Leucine Rich repeats (2 copies) Pacifastin_I PF05375.13 EGG15335.1 - 0.16 11.8 0.1 0.16 11.8 0.1 1.6 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) LRR_6 PF13516.6 EGG15336.1 - 0.0043 17.0 7.7 0.28 11.3 0.2 4.3 4 0 0 4 4 4 2 Leucine Rich repeat ABC_tran PF00005.27 EGG15337.1 - 5.3e-27 95.0 0.0 1.5e-26 93.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGG15337.1 - 5.8e-06 26.3 0.2 1.7e-05 24.8 0.2 1.7 1 0 0 1 1 1 1 RsgA GTPase DNase_II PF03265.15 EGG15337.1 - 2e-05 24.1 0.0 0.18 11.0 0.0 2.6 2 0 0 2 2 2 2 Deoxyribonuclease II AAA_17 PF13207.6 EGG15337.1 - 0.023 15.1 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGG15337.1 - 0.025 13.7 0.2 0.044 12.8 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EGG15337.1 - 0.027 14.2 0.8 0.064 13.0 0.8 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EGG15337.1 - 0.048 13.6 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EGG15337.1 - 0.058 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGG15337.1 - 0.087 13.2 0.0 0.32 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGG15337.1 - 0.092 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EGG15337.1 - 0.094 12.6 0.2 0.53 10.2 0.1 2.1 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.6 EGG15337.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EGG15337.1 - 0.25 11.8 4.7 0.15 12.6 1.2 2.5 2 0 0 2 2 2 0 AAA domain HEAT PF02985.22 EGG15338.1 - 0.0019 18.3 0.7 0.047 13.9 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat Cnd2 PF05786.14 EGG15338.1 - 1.1 7.8 30.5 1.1 7.9 25.5 2.1 2 0 0 2 2 2 0 Condensin complex subunit 2 SDA1 PF05285.12 EGG15338.1 - 1.8 7.9 71.1 1.4 8.3 64.0 2.4 2 0 0 2 2 2 0 SDA1 Neur_chan_memb PF02932.16 EGG15338.1 - 3.9 7.5 6.6 14 5.6 6.6 1.9 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MID_MedPIWI PF18296.1 EGG15338.1 - 3.9 7.2 10.8 15 5.3 10.6 2.2 1 1 0 1 1 1 0 MID domain of medPIWI Presenilin PF01080.17 EGG15338.1 - 4.5 5.9 27.4 7.3 5.2 27.4 1.2 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 EGG15339.1 - 3.2e-46 157.8 0.0 1e-45 156.2 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain RhoGEF PF00621.20 EGG15339.1 - 3.8e-35 121.8 0.7 1.2e-34 120.2 0.5 2.0 2 0 0 2 2 2 1 RhoGEF domain Pkinase_Tyr PF07714.17 EGG15339.1 - 1.2e-34 119.8 0.0 2.3e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EGG15339.1 - 2.9e-06 27.7 0.1 1.5e-05 25.4 0.0 2.4 2 1 0 2 2 2 1 PH domain APH PF01636.23 EGG15339.1 - 0.0054 16.7 0.0 0.1 12.5 0.0 2.6 2 1 0 3 3 3 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGG15339.1 - 0.047 13.0 1.2 0.59 9.4 0.0 2.9 3 0 0 3 3 3 0 Ecdysteroid kinase Med31 PF05669.12 EGG15339.1 - 0.16 12.0 1.4 2.7 8.1 0.1 2.7 2 0 0 2 2 2 0 SOH1 E1_dh PF00676.20 EGG15340.1 - 2e-107 358.6 0.1 2.5e-107 358.3 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EGG15340.1 - 0.049 12.8 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase OppC_N PF12911.7 EGG15340.1 - 0.096 12.7 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C TILa PF12714.7 EGG15341.1 - 0.22 11.5 14.2 1.6 8.8 6.9 2.4 2 0 0 2 2 2 0 TILa domain CAP_N PF01213.19 EGG15341.1 - 0.99 8.8 3.2 1.7 8.1 3.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.25 EGG15342.1 - 0.038 13.4 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Ring_hydroxyl_A PF00848.19 EGG15342.1 - 0.062 13.3 0.1 0.071 13.1 0.1 1.1 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) Pkinase PF00069.25 EGG15343.1 - 6.1e-19 68.4 0.1 1.5e-18 67.2 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG15343.1 - 8.4e-06 25.3 0.1 5.3e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG15343.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Adenylsucc_synt PF00709.21 EGG15345.1 - 6.7e-179 595.2 0.1 7.5e-179 595.0 0.1 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ras PF00071.22 EGG15346.1 - 1.4e-60 203.6 0.1 1.6e-60 203.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG15346.1 - 8.5e-34 116.4 0.0 1.2e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG15346.1 - 1.8e-15 56.9 0.0 2.2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGG15346.1 - 8.3e-06 25.8 0.1 0.045 13.7 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGG15346.1 - 0.00028 20.3 0.1 0.00031 20.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EGG15346.1 - 0.00093 18.8 0.0 0.0046 16.5 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGG15346.1 - 0.0013 18.8 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGG15346.1 - 0.0039 16.7 0.1 0.0062 16.0 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGG15346.1 - 0.0053 16.3 0.1 0.026 14.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 EGG15346.1 - 0.042 13.3 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EGG15346.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 EGG15346.1 - 0.071 13.5 0.0 0.087 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EGG15346.1 - 0.085 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGG15346.1 - 0.092 13.0 0.0 0.17 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain B12D PF06522.11 EGG15347.1 - 0.00014 21.6 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit zf-RING_2 PF13639.6 EGG15348.1 - 1.2e-08 35.2 10.5 1.2e-08 35.2 10.5 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGG15348.1 - 1.5e-06 27.9 9.5 3.9e-06 26.6 9.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG15348.1 - 5e-05 23.1 7.5 0.00011 22.0 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG15348.1 - 6.1e-05 22.8 9.2 6.1e-05 22.8 9.2 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG15348.1 - 0.00022 21.2 9.1 0.00022 21.2 9.1 2.0 2 0 0 2 2 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGG15348.1 - 0.00043 20.5 10.6 0.0038 17.5 10.6 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EGG15348.1 - 0.0008 19.2 7.2 0.0022 17.7 7.2 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 EGG15348.1 - 0.00097 19.1 2.2 0.0018 18.3 2.2 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.6 EGG15348.1 - 0.001 19.0 10.0 0.001 19.0 10.0 1.7 2 0 0 2 2 1 1 zinc-RING finger domain BAF1_ABF1 PF04684.13 EGG15348.1 - 0.0026 16.9 18.7 0.0042 16.2 18.7 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Prok-RING_4 PF14447.6 EGG15348.1 - 0.012 15.5 8.1 0.012 15.5 8.1 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGG15348.1 - 0.056 13.6 8.0 0.23 11.6 8.0 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EGG15348.1 - 0.082 13.1 4.7 0.16 12.1 4.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 EGG15348.1 - 0.13 12.1 9.8 0.029 14.1 6.4 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_6 PF14835.6 EGG15348.1 - 0.13 12.1 2.5 0.26 11.2 2.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EGG15348.1 - 0.25 11.4 6.3 3.2 7.9 6.3 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 EGG15348.1 - 0.42 10.7 7.5 1.4 9.0 7.5 2.0 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 EGG15348.1 - 4.1 7.1 8.8 7.6 6.2 8.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HPS3_Mid PF14762.6 EGG15349.1 - 1.6e-41 142.4 4.3 3e-41 141.5 4.3 1.5 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, middle region HPS3_N PF14761.6 EGG15349.1 - 1.8e-31 109.4 0.0 4.8e-31 108.0 0.0 1.7 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 HPS3_C PF14763.6 EGG15349.1 - 0.011 15.1 0.3 0.5 9.7 0.0 2.7 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3, C-terminal TPR_8 PF13181.6 EGG15349.1 - 0.061 13.6 0.2 0.57 10.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.22 EGG15350.1 - 1.1e-70 238.7 0.3 1.3e-70 238.4 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5343 PF17278.2 EGG15350.1 - 0.03 14.4 0.2 0.057 13.5 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5343) RE_SinI PF09570.10 EGG15351.1 - 0.066 12.4 0.1 0.071 12.3 0.1 1.1 1 0 0 1 1 1 0 SinI restriction endonuclease PhoLip_ATPase_C PF16212.5 EGG15352.1 - 2.7e-56 191.1 29.6 1.1e-49 169.5 19.7 2.9 2 1 1 3 3 3 2 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGG15352.1 - 1.8e-27 94.8 3.5 4.7e-27 93.5 3.5 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGG15352.1 - 1.6e-08 34.5 0.0 7.5e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGG15352.1 - 2.2e-06 27.3 4.5 3.1e-06 26.8 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGG15352.1 - 7.5e-06 26.4 0.1 0.13 12.5 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGG15352.1 - 0.017 14.9 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase tRNA_anti-codon PF01336.25 EGG15353.1 - 0.037 14.0 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Sporozoite_P67 PF05642.11 EGG15353.1 - 0.049 11.7 13.4 0.072 11.2 13.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 EGG15353.1 - 0.062 11.5 26.4 0.093 10.9 26.4 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EGG15353.1 - 0.42 10.0 28.1 0.62 9.4 28.1 1.3 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 EGG15353.1 - 0.48 9.1 10.6 0.72 8.5 10.6 1.4 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 EGG15353.1 - 0.5 9.7 25.1 0.7 9.2 25.1 1.2 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 EGG15353.1 - 2.9 6.6 15.8 4.1 6.1 15.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Roughex PF06020.11 EGG15353.1 - 3 6.8 18.9 3 6.9 17.0 1.8 2 0 0 2 2 2 0 Drosophila roughex protein CDC45 PF02724.14 EGG15353.1 - 3.8 5.7 27.2 4.9 5.3 27.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 EGG15353.1 - 7.1 5.7 14.8 12 5.0 14.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit V_ATPase_I PF01496.19 EGG15353.1 - 7.1 4.4 10.4 10 3.9 10.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DNA_pol_phi PF04931.13 EGG15353.1 - 8.7 4.3 27.1 12 3.8 27.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 EGG15353.1 - 8.7 5.2 8.9 15 4.5 8.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ribosomal_L13 PF00572.18 EGG15354.1 - 1.4e-08 35.0 0.1 7.2e-06 26.3 0.1 2.5 1 1 0 1 1 1 1 Ribosomal protein L13 Pkinase_Tyr PF07714.17 EGG15355.1 - 4.4e-59 199.9 0.0 5.4e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG15355.1 - 1.2e-53 182.2 0.0 1.6e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 EGG15355.1 - 4.6e-05 22.5 0.1 6.6e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGG15355.1 - 0.0013 17.6 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGG15355.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG15355.1 - 0.036 14.0 0.0 0.085 12.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG15355.1 - 0.068 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Methyltransf_16 PF10294.9 EGG15356.1 - 4.1e-23 82.0 0.1 4.1e-23 82.0 0.1 1.7 2 0 0 2 2 2 1 Lysine methyltransferase MTS PF05175.14 EGG15356.1 - 0.00071 19.2 0.0 0.00071 19.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGG15356.1 - 0.0011 18.9 0.0 0.0021 17.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG15356.1 - 0.017 15.8 0.0 0.053 14.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGG15356.1 - 0.68 10.7 5.9 0.94 10.3 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Orf78 PF06024.12 EGG15356.1 - 3.8 7.9 5.4 11 6.4 5.5 1.7 2 0 0 2 2 2 0 Orf78 (ac78) Tubulin_3 PF14881.6 EGG15357.1 - 4.2e-24 85.2 0.2 7.4e-24 84.4 0.2 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EGG15357.1 - 9.2e-11 42.1 0.4 9.2e-11 42.1 0.4 2.1 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EGG15357.1 - 3.1e-09 37.3 0.7 2.7e-07 31.0 0.0 2.5 1 1 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain DUF3723 PF12520.8 EGG15357.1 - 0.023 13.4 0.0 0.084 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3723) Vps54 PF07928.12 EGG15358.1 - 1.4e-44 151.7 2.5 3.8e-44 150.4 0.2 2.8 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 EGG15358.1 - 3.7e-13 49.4 3.3 3.7e-13 49.4 3.3 2.4 4 0 0 4 4 4 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 EGG15358.1 - 6.8e-05 23.0 1.1 6.8e-05 23.0 1.1 3.1 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.12 EGG15358.1 - 0.00045 19.3 4.1 0.00092 18.3 4.1 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal tRNA-synt_1e PF01406.19 EGG15358.1 - 0.17 11.2 1.6 0.31 10.4 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Exonuc_VII_L PF02601.15 EGG15359.1 - 0.017 14.7 11.1 0.026 14.1 11.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CCSAP PF15748.5 EGG15359.1 - 1.3 9.1 10.7 2.1 8.5 10.7 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated ALMT PF11744.8 EGG15359.1 - 2.1 7.1 19.8 4.3 6.1 19.8 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter SKA1 PF07160.12 EGG15359.1 - 5 6.9 24.6 0.6 9.9 18.1 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Ferric_reduct PF01794.19 EGG15361.1 - 0.015 15.4 2.9 0.018 15.2 0.6 2.2 1 1 1 2 2 2 0 Ferric reductase like transmembrane component DHHC PF01529.20 EGG15362.1 - 2.1e-37 128.2 10.4 2.1e-37 128.2 10.4 2.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase PBP1_TM PF14812.6 EGG15362.1 - 0.14 12.5 4.8 0.49 10.8 4.8 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF347 PF03988.12 EGG15362.1 - 0.36 11.1 4.8 1 9.6 4.8 1.8 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) zf-ribbon_3 PF13248.6 EGG15362.1 - 0.45 10.0 4.6 1.1 8.8 4.6 1.7 1 0 0 1 1 1 0 zinc-ribbon domain EptA_B_N PF08019.12 EGG15362.1 - 0.57 10.0 7.7 0.67 9.8 0.4 2.4 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB zinc_ribbon_2 PF13240.6 EGG15362.1 - 1.8 8.4 8.0 6.2 6.7 8.0 2.0 1 0 0 1 1 1 0 zinc-ribbon domain Utp14 PF04615.13 EGG15362.1 - 2.9 6.4 18.9 5.3 5.5 18.9 1.3 1 0 0 1 1 1 0 Utp14 protein MatE PF01554.18 EGG15363.1 - 5.9e-62 208.1 33.8 7.4e-35 120.0 10.1 2.4 3 0 0 3 3 3 2 MatE T4SS PF07996.11 EGG15363.1 - 0.2 12.0 4.2 0.37 11.2 4.2 1.4 1 0 0 1 1 1 0 Type IV secretion system proteins HATPase_c PF02518.26 EGG15364.1 - 1.6e-29 102.6 0.6 4.7e-29 101.2 0.4 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGG15364.1 - 8e-18 64.6 0.6 2.3e-15 56.7 0.0 3.4 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 EGG15364.1 - 2e-13 50.2 0.0 4.2e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 EGG15364.1 - 2.7e-05 24.1 0.0 5.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 PAS domain Ribosomal_S4e PF00900.20 EGG15366.1 - 1.7e-29 101.6 0.2 3.3e-29 100.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EGG15366.1 - 1.1e-20 73.0 0.1 1.8e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EGG15366.1 - 1.4e-19 69.9 9.2 2.8e-19 68.9 9.2 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EGG15366.1 - 1.7e-09 37.2 0.0 2.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EGG15366.1 - 0.0021 18.0 0.6 0.0055 16.6 0.0 2.0 2 0 0 2 2 2 1 KOW motif zf-Tim10_DDP PF02953.15 EGG15367.1 - 4.3e-10 39.1 7.0 5.1e-10 38.9 7.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger NCD3G PF07562.14 EGG15367.1 - 0.044 13.8 0.1 0.055 13.4 0.1 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR RRM_1 PF00076.22 EGG15368.1 - 3e-20 71.8 0.1 5e-20 71.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 EGG15368.1 - 6.5e-18 65.0 10.4 1.6e-17 63.7 10.4 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 YflT PF11181.8 EGG15368.1 - 0.0091 16.5 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 Heat induced stress protein YflT RRM_7 PF16367.5 EGG15368.1 - 0.099 12.8 0.0 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif BRAP2 PF07576.12 EGG15368.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 Lyase_1 PF00206.20 EGG15369.1 - 4.3e-114 381.1 0.1 5.8e-114 380.7 0.1 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EGG15369.1 - 5.1e-25 87.7 0.5 1.8e-24 85.9 0.1 2.1 2 0 0 2 2 2 1 Fumarase C C-terminus Bromodomain PF00439.25 EGG15370.1 - 1.8e-14 53.6 0.2 6.8e-14 51.7 0.2 2.1 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 EGG15370.1 - 0.00039 20.4 0.0 0.00098 19.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated COMM_domain PF07258.14 EGG15371.1 - 1.1e-14 54.2 0.3 1.1e-14 54.2 0.3 2.0 2 1 1 3 3 3 1 COMM domain SOG2 PF10428.9 EGG15371.1 - 0.017 14.4 6.4 0.017 14.3 6.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4614 PF15391.6 EGG15371.1 - 0.021 14.8 6.3 0.024 14.6 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CCDC24 PF15669.5 EGG15371.1 - 3.2 7.6 5.6 4.2 7.2 5.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family FAA_hydrolase PF01557.18 EGG15373.1 - 1.9e-67 227.1 0.0 2.4e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Collar PF07484.12 EGG15374.1 - 2e-21 75.7 0.0 3.7e-06 26.9 0.0 3.7 3 0 0 3 3 3 3 Phage Tail Collar Domain DUF5466 PF17554.2 EGG15374.1 - 0.021 15.0 0.4 0.16 12.2 0.2 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5466) GlgS PF08971.11 EGG15374.1 - 4.6 7.3 11.0 3.6 7.7 1.0 3.4 3 0 0 3 3 3 0 Glycogen synthesis protein FNIP PF05725.12 EGG15375.1 - 0.004 17.3 31.6 0.16 12.2 1.2 8.4 10 0 0 10 10 10 4 FNIP Repeat Rxt3 PF08642.10 EGG15375.1 - 0.5 11.1 2.3 0.74 10.6 0.5 2.0 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Fez1 PF06818.15 EGG15376.1 - 0.00011 22.7 1.8 0.00014 22.4 1.8 1.3 1 0 0 1 1 1 1 Fez1 DUF1664 PF07889.12 EGG15376.1 - 0.00049 20.1 5.7 0.001 19.1 5.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 EGG15376.1 - 0.0015 18.6 8.2 0.0024 17.9 6.3 1.8 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 EGG15376.1 - 0.0016 18.6 5.5 0.0026 17.9 5.0 1.6 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 EGG15376.1 - 0.0023 16.9 8.2 0.0035 16.3 8.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein MAD PF05557.13 EGG15376.1 - 0.0024 16.4 4.6 0.0027 16.2 4.6 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein RasGAP_C PF03836.15 EGG15376.1 - 0.0027 17.8 2.5 0.0058 16.8 2.5 1.7 1 0 0 1 1 1 1 RasGAP C-terminus APG6_N PF17675.1 EGG15376.1 - 0.0028 18.2 5.2 0.0052 17.3 5.2 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region EzrA PF06160.12 EGG15376.1 - 0.0046 15.2 6.4 0.0058 14.9 6.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA ATG16 PF08614.11 EGG15376.1 - 0.007 16.6 4.9 0.011 16.0 4.9 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Atg14 PF10186.9 EGG15376.1 - 0.012 14.8 2.9 0.013 14.6 2.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fmp27_WPPW PF10359.9 EGG15376.1 - 0.015 14.2 2.1 0.02 13.7 2.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc29 PF17082.5 EGG15376.1 - 0.015 15.1 1.1 0.022 14.6 1.1 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF4201 PF13870.6 EGG15376.1 - 0.019 14.7 4.9 0.045 13.5 4.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) MscS_porin PF12795.7 EGG15376.1 - 0.041 13.4 3.3 0.071 12.7 3.3 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain CorA PF01544.18 EGG15376.1 - 0.052 12.9 0.7 0.092 12.0 0.7 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SlyX PF04102.12 EGG15376.1 - 0.055 14.1 0.4 0.055 14.1 0.4 3.2 2 1 1 3 3 2 0 SlyX DUF5082 PF16888.5 EGG15376.1 - 0.058 13.7 10.4 0.1 12.9 2.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) CCDC-167 PF15188.6 EGG15376.1 - 0.076 13.4 4.0 0.24 11.8 4.0 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 COG5 PF10392.9 EGG15376.1 - 0.078 13.2 0.8 0.54 10.4 0.1 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 TSKS PF15358.6 EGG15376.1 - 0.11 10.8 2.6 0.14 10.5 2.6 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate TMPIT PF07851.13 EGG15376.1 - 0.12 11.5 2.8 0.16 11.2 2.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF16 PF01519.16 EGG15376.1 - 0.13 12.8 12.2 0.064 13.8 8.0 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 HrpB7 PF09486.10 EGG15376.1 - 0.13 12.6 1.4 7.7 6.9 0.5 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) bZIP_1 PF00170.21 EGG15376.1 - 0.19 11.9 6.4 0.2 11.8 2.8 2.7 1 1 2 3 3 3 0 bZIP transcription factor Fungal_TACC PF12709.7 EGG15376.1 - 0.22 12.0 8.6 5 7.6 0.5 2.9 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DivIC PF04977.15 EGG15376.1 - 0.22 11.3 15.7 0.14 11.9 2.5 3.0 1 1 1 3 3 3 0 Septum formation initiator She9_MDM33 PF05546.11 EGG15376.1 - 0.25 11.1 3.4 0.37 10.6 2.3 1.9 1 1 1 2 2 2 0 She9 / Mdm33 family Spc42p PF11544.8 EGG15376.1 - 0.27 11.3 7.8 5.4 7.1 1.0 3.2 1 1 2 3 3 3 0 Spindle pole body component Spc42p Tup_N PF08581.10 EGG15376.1 - 0.29 11.5 6.4 0.5 10.7 5.5 1.9 1 1 0 1 1 1 0 Tup N-terminal DUF4988 PF16378.5 EGG15376.1 - 0.3 10.7 6.3 0.45 10.2 1.7 2.2 1 1 1 2 2 2 0 Domain of unknown function DASH_Spc19 PF08287.11 EGG15376.1 - 0.3 11.0 4.8 7.5 6.4 0.4 2.4 1 1 1 2 2 2 0 Spc19 USP8_interact PF08941.10 EGG15376.1 - 0.32 10.8 3.3 1.3 8.8 3.3 2.1 1 1 0 1 1 1 0 USP8 interacting Csm1_N PF18504.1 EGG15376.1 - 0.36 11.2 10.4 0.19 12.1 1.4 2.8 1 1 2 3 3 2 0 Csm1 N-terminal domain Prefoldin PF02996.17 EGG15376.1 - 0.43 10.5 8.2 0.14 12.0 2.2 2.6 1 1 1 2 2 2 0 Prefoldin subunit Spectrin PF00435.21 EGG15376.1 - 0.49 10.9 6.5 1.8 9.1 5.0 2.5 1 1 1 2 2 2 0 Spectrin repeat Cast PF10174.9 EGG15376.1 - 0.51 8.5 11.0 2.7 6.1 11.0 1.8 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone PspA_IM30 PF04012.12 EGG15376.1 - 0.54 9.8 4.7 0.57 9.7 2.7 1.8 1 1 1 2 2 2 0 PspA/IM30 family Cluap1 PF10234.9 EGG15376.1 - 0.56 9.6 7.1 0.86 8.9 6.9 1.6 1 1 0 1 1 1 0 Clusterin-associated protein-1 Laminin_II PF06009.12 EGG15376.1 - 0.59 10.2 8.2 0.46 10.5 6.8 1.6 2 0 0 2 2 1 0 Laminin Domain II FliJ PF02050.16 EGG15376.1 - 0.75 10.0 6.7 2.3 8.4 5.0 2.2 1 1 0 1 1 1 0 Flagellar FliJ protein CENP-H PF05837.12 EGG15376.1 - 0.75 10.2 5.6 1.4 9.4 5.6 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 EGG15376.1 - 0.85 9.8 8.5 9.7 6.4 7.7 2.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 EGG15376.1 - 0.93 9.8 6.1 12 6.2 4.8 2.8 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) HAUS5 PF14817.6 EGG15376.1 - 0.94 8.2 6.5 3.9 6.1 0.6 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 DUF3450 PF11932.8 EGG15376.1 - 1.1 8.5 5.2 2.5 7.3 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 EGG15376.1 - 1.1 9.3 8.8 0.89 9.6 2.0 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HMMR_N PF15905.5 EGG15376.1 - 1.2 8.5 11.1 1.8 8.0 11.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 EGG15376.1 - 1.4 8.2 5.0 3.5 6.9 5.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Med9 PF07544.13 EGG15376.1 - 1.4 9.0 10.4 1.5 8.9 2.6 3.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Occludin_ELL PF07303.13 EGG15376.1 - 1.6 9.5 7.3 3.7 8.3 3.5 2.7 1 1 2 3 3 3 0 Occludin homology domain TMF_DNA_bd PF12329.8 EGG15376.1 - 1.6 8.8 9.3 3.3 7.8 1.5 2.7 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cep57_MT_bd PF06657.13 EGG15376.1 - 1.8 9.0 6.7 3.9 8.0 0.1 3.1 1 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF4200 PF13863.6 EGG15376.1 - 3.6 8.0 11.5 6.9 7.1 2.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF1045 PF06299.12 EGG15377.1 - 0.0065 16.5 0.0 0.0092 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1045) 2_5_RNA_ligase2 PF13563.6 EGG15377.1 - 0.037 13.9 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily PTR2 PF00854.21 EGG15379.1 - 1e-96 324.2 17.9 1.5e-96 323.7 17.9 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EGG15379.1 - 4.4e-07 29.1 25.7 3.9e-05 22.8 11.9 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Ferric_reduct PF01794.19 EGG15380.1 - 3.5e-05 23.9 4.9 1.9 8.6 0.1 3.4 3 0 0 3 3 3 3 Ferric reductase like transmembrane component Nse4-Nse3_bdg PF15412.6 EGG15380.1 - 0.0016 18.5 0.0 5.1 7.3 0.0 3.3 2 0 0 2 2 2 2 Binding domain of Nse4/EID3 to Nse3-MAGE Cas6_N PF17952.1 EGG15380.1 - 0.081 13.2 1.6 19 5.6 0.2 3.2 2 0 0 2 2 2 0 Cas6 N-terminal domain DUF3872 PF12988.7 EGG15380.1 - 2.1 8.2 8.3 5.1 6.9 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3872) Methyltransf_28 PF02636.17 EGG15384.1 - 2.4e-69 233.9 0.0 3.5e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CBM49 PF09478.10 EGG15385.1 - 3.2e-19 69.0 0.1 4.6e-19 68.5 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Methyltransf_25 PF13649.6 EGG15388.1 - 5.6e-08 33.4 0.0 1.2e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG15388.1 - 8.4e-06 26.3 0.0 2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG15388.1 - 2.2e-05 25.1 0.0 7.1e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG15388.1 - 0.0035 16.7 0.0 0.0064 15.8 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGG15388.1 - 0.045 13.5 0.0 0.19 11.5 0.0 1.9 1 1 0 2 2 2 0 Methyltransferase domain Acyl_transf_3 PF01757.22 EGG15389.1 - 5.8e-06 25.6 12.3 8.3e-06 25.1 10.6 2.0 2 1 0 2 2 2 1 Acyltransferase family Promethin PF16015.5 EGG15389.1 - 0.0074 16.2 2.2 0.0074 16.2 2.2 3.7 3 1 1 4 4 4 1 Promethin MpPF26 PF07666.11 EGG15389.1 - 0.043 13.9 0.1 0.043 13.9 0.1 3.0 4 0 0 4 4 4 0 M penetrans paralogue family 26 DUF962 PF06127.11 EGG15389.1 - 0.54 10.4 11.8 0.12 12.4 1.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF962) DUF4396 PF14342.6 EGG15389.1 - 0.68 10.3 6.2 13 6.1 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4396) Acyl_transf_3 PF01757.22 EGG15390.1 - 1.4e-10 40.8 38.6 1.4e-10 40.8 38.6 3.0 3 0 0 3 3 3 2 Acyltransferase family ODV-E18 PF10717.9 EGG15390.1 - 0.46 10.4 5.7 0.85 9.5 1.4 2.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF4834 PF16118.5 EGG15390.1 - 2.7 9.0 4.7 7.9 7.5 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PI3Ka PF00613.20 EGG15391.1 - 4.6e-60 202.2 0.8 1e-59 201.1 0.8 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGG15391.1 - 1.1e-53 182.7 0.1 1.8e-52 178.6 0.1 2.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EGG15391.1 - 2.8e-18 66.2 1.2 1.3e-17 64.0 0.0 2.6 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 EGG15391.1 - 5e-14 52.4 1.0 2.5e-10 40.4 0.0 2.9 2 0 0 2 2 2 2 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 EGG15391.1 - 0.0017 17.8 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) ETRAMP PF09716.10 EGG15391.1 - 0.25 11.4 2.2 1.5 8.9 0.5 3.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Amino_oxidase PF01593.24 EGG15392.1 - 1.3e-29 103.8 0.0 1.6e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGG15392.1 - 4.7e-12 46.0 0.0 1.1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG15392.1 - 0.0081 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGG15392.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ribosomal_S6e PF01092.19 EGG15393.1 - 4.2e-52 175.4 0.2 7.9e-52 174.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S6e Sybindin PF04099.12 EGG15394.1 - 7.3e-48 162.1 0.3 8.7e-48 161.9 0.3 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EGG15394.1 - 1.1e-06 28.8 0.1 1.6e-06 28.3 0.1 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region GTP_EFTU PF00009.27 EGG15395.1 - 6.5e-32 110.6 1.1 2.4e-31 108.8 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D4 PF14578.6 EGG15395.1 - 6.6e-16 58.0 0.3 2e-15 56.4 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 IF-2 PF11987.8 EGG15395.1 - 3.1e-14 53.0 0.8 3.1e-14 53.0 0.8 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EGG15395.1 - 1.8e-08 34.7 14.9 2.6e-07 30.9 0.1 4.4 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGG15395.1 - 2.8e-07 30.6 0.0 9.1e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGG15395.1 - 0.0017 18.6 0.0 0.0065 16.7 0.0 2.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGG15395.1 - 0.011 15.5 0.1 0.084 12.6 0.0 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EGG15395.1 - 0.037 14.3 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain zf-WRNIP1_ubi PF18279.1 EGG15397.1 - 0.009 16.6 3.5 0.34 11.6 0.6 2.8 2 0 0 2 2 2 1 Werner helicase-interacting protein 1 ubiquitin-binding domain SchA_CurD PF04486.12 EGG15397.1 - 0.12 12.5 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 SchA/CurD like domain RNase_H2_suC PF08615.11 EGG15397.1 - 0.59 10.3 3.9 0.32 11.2 0.1 2.4 3 0 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) zinc_ribbon_4 PF13717.6 EGG15397.1 - 0.7 9.9 5.0 8.6 6.4 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain RPN2_C PF18004.1 EGG15397.1 - 0.72 9.8 7.5 1.7 8.5 7.5 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ribosomal_L6e PF01159.19 EGG15397.1 - 0.83 10.2 4.7 2.9 8.4 4.7 1.9 1 0 0 1 1 1 0 Ribosomal protein L6e CDC45 PF02724.14 EGG15397.1 - 2.9 6.1 11.0 5.6 5.1 11.0 1.3 1 0 0 1 1 1 0 CDC45-like protein PA14 PF07691.12 EGG15398.1 - 4.5e-06 26.5 0.0 9.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 PA14 domain fn3 PF00041.21 EGG15399.1 - 5e-18 65.2 24.7 7.5e-05 23.0 1.0 7.1 6 2 0 6 6 6 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 EGG15399.1 - 3.4e-05 24.3 32.9 0.025 15.1 3.2 6.3 3 2 2 5 5 5 3 Purple acid Phosphatase, N-terminal domain Arylsulfotran_N PF17425.2 EGG15399.1 - 0.00024 21.1 29.6 0.032 14.2 0.2 6.8 7 0 0 7 7 7 2 Arylsulfotransferase Ig-like domain EB PF01683.18 EGG15399.1 - 0.00099 19.4 1.4 0.0056 16.9 1.4 2.3 1 0 0 1 1 1 1 EB module DUF2369 PF10179.9 EGG15399.1 - 0.0013 19.0 14.1 1.8 9.0 0.4 5.5 5 0 0 5 5 5 2 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 EGG15399.1 - 0.0016 18.7 6.0 1.7 9.0 0.1 4.5 4 0 0 4 4 4 2 Interferon-alpha/beta receptor, fibronectin type III EGF_2 PF07974.13 EGG15399.1 - 0.0036 17.6 13.0 0.014 15.8 13.0 2.1 1 0 0 1 1 1 1 EGF-like domain SusE PF14292.6 EGG15399.1 - 0.0073 16.5 2.3 0.0073 16.5 2.3 5.6 4 3 3 7 7 7 1 SusE outer membrane protein EGF PF00008.27 EGG15399.1 - 0.35 11.2 10.8 0.14 12.5 7.0 2.5 2 0 0 2 2 2 0 EGF-like domain DUF1869 PF08956.10 EGG15399.1 - 1.3 9.0 8.6 0.15 12.0 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1869) I-EGF_1 PF18372.1 EGG15399.1 - 7.6 6.7 10.8 31 4.8 10.8 2.2 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Metallothio_Euk PF12749.7 EGG15400.1 - 0.0065 16.6 3.7 0.014 15.5 3.5 1.6 1 1 0 1 1 1 1 Eukaryotic metallothionein RRM_1 PF00076.22 EGG15403.1 - 0.0025 17.6 0.0 0.0093 15.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG15403.1 - 0.017 14.7 0.0 0.043 13.4 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EGG15403.1 - 0.052 13.4 0.1 0.34 10.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4523) KIAA1430 PF13879.6 EGG15404.1 - 8.5 7.2 7.5 0.36 11.6 0.8 2.2 3 0 0 3 3 3 0 KIAA1430 homologue RRM_1 PF00076.22 EGG15405.1 - 0.0073 16.1 0.0 0.038 13.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CadC_C1 PF18500.1 EGG15405.1 - 0.09 12.9 1.9 0.31 11.2 0.5 2.4 2 1 0 2 2 2 0 CadC C-terminal domain 1 Ribosomal_S6 PF01250.17 EGG15405.1 - 0.091 13.1 0.0 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S6 CENP-B_dimeris PF09026.10 EGG15406.1 - 0.17 12.3 5.2 0.33 11.4 5.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SR-25 PF10500.9 EGG15408.1 - 0.0031 17.2 1.6 0.0031 17.2 1.6 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein UBD PF16455.5 EGG15408.1 - 0.017 15.4 0.2 0.058 13.7 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-binding domain Gly_acyl_tr_N PF06021.11 EGG15408.1 - 0.57 10.2 7.3 1 9.5 6.7 1.7 1 1 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase IMUP PF15761.5 EGG15408.1 - 3.6 8.3 7.3 0.65 10.7 2.5 2.0 2 0 0 2 2 2 0 Immortalisation up-regulated protein LRR_6 PF13516.6 EGG15409.1 - 8.1e-10 38.0 14.8 0.05 13.7 0.2 8.9 9 0 0 9 9 9 5 Leucine Rich repeat Pentapeptide_4 PF13599.6 EGG15410.1 - 2.5e-16 59.6 45.6 3.4e-09 36.7 18.0 4.0 2 1 2 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 EGG15410.1 - 1.5e-08 34.1 20.4 0.00022 20.8 2.7 4.2 2 2 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 EGG15410.1 - 2.7e-08 33.8 17.5 2e-05 24.6 7.8 3.2 2 2 0 2 2 2 2 Pentapeptide repeats (9 copies) zf-RING_5 PF14634.6 EGG15410.1 - 0.0003 20.7 12.4 0.0003 20.7 12.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG15410.1 - 0.00093 19.2 8.3 0.0035 17.3 8.3 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGG15410.1 - 0.0017 18.7 13.9 0.0017 18.7 13.9 2.8 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 EGG15410.1 - 0.01 15.7 6.1 0.01 15.7 6.1 3.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGG15410.1 - 0.16 11.9 18.6 0.1 12.5 14.4 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGG15410.1 - 0.16 12.1 10.3 0.15 12.2 7.9 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF3666 PF12408.8 EGG15410.1 - 1.1 8.5 2.9 2 7.7 2.1 1.8 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase DDHD PF02862.17 EGG15411.1 - 3.9e-28 99.1 15.8 3.9e-28 99.1 15.8 3.9 2 2 0 2 2 2 1 DDHD domain BIV_Env PF05858.12 EGG15411.1 - 3.7 5.6 7.6 9 4.3 7.6 1.5 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) DUF962 PF06127.11 EGG15412.1 - 1.4e-33 114.8 0.7 1.5e-33 114.7 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Pico_P1A PF02226.16 EGG15413.1 - 0.42 10.7 3.6 18 5.4 1.4 2.6 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) Fuseless PF15993.5 EGG15414.1 - 0.016 14.4 0.6 0.016 14.4 0.6 1.6 2 0 0 2 2 2 0 Fuseless DUF3439 PF11921.8 EGG15414.1 - 0.057 13.4 1.8 0.14 12.1 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NOA36 PF06524.12 EGG15418.1 - 0.03 13.6 7.7 0.039 13.3 7.7 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EGG15418.1 - 0.93 7.6 10.0 1.1 7.4 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 EGG15418.1 - 1.6 8.1 7.8 2 7.8 7.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.11 EGG15418.1 - 1.6 7.2 6.2 1.9 6.9 6.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2722 PF10846.8 EGG15418.1 - 1.6 7.6 13.3 1.9 7.4 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SDA1 PF05285.12 EGG15418.1 - 6.4 6.1 13.6 8.1 5.8 13.6 1.1 1 0 0 1 1 1 0 SDA1 DUF2076 PF09849.9 EGG15418.1 - 7.4 6.5 14.6 9 6.3 14.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FNIP PF05725.12 EGG15419.1 - 1.3e-06 28.4 34.6 0.57 10.4 0.2 10.5 8 3 1 9 9 9 6 FNIP Repeat FNIP PF05725.12 EGG15420.1 - 0.00059 19.9 43.3 2.7 8.2 0.1 10.8 7 3 7 14 14 14 11 FNIP Repeat FNIP PF05725.12 EGG15421.1 - 2e-06 27.9 30.1 0.022 14.9 1.2 8.8 6 3 2 8 8 8 6 FNIP Repeat GFA PF04828.14 EGG15422.1 - 1.2e-07 31.9 2.4 1.2e-07 31.9 2.4 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF2321 PF10083.9 EGG15422.1 - 0.056 13.1 2.0 0.076 12.6 2.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Coiled PF05710.12 EGG15423.1 - 2.1e-07 31.7 5.4 2.1e-07 31.6 5.4 1.1 1 0 0 1 1 1 1 Coiled coil Dynamitin PF04912.14 EGG15425.1 - 8.7e-104 347.9 27.9 1e-103 347.7 27.9 1.0 1 0 0 1 1 1 1 Dynamitin Mannitol_dh PF01232.23 EGG15425.1 - 0.024 14.8 1.7 0.078 13.1 1.7 1.9 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain IMPa_helical PF18642.1 EGG15425.1 - 0.071 13.5 1.4 21 5.6 0.1 3.2 2 1 0 2 2 2 0 Immunomodulating metalloprotease helical domain Baculo_PEP_C PF04513.12 EGG15425.1 - 0.57 10.2 25.6 0.024 14.7 7.6 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran_CTD PF16326.5 EGG15425.1 - 1.2 9.5 13.4 1.6 9.0 0.6 5.2 4 2 1 5 5 5 0 ABC transporter C-terminal domain FlxA PF14282.6 EGG15425.1 - 1.4 8.9 30.2 0.71 9.9 2.4 4.4 4 0 0 4 4 4 0 FlxA-like protein DUF1515 PF07439.11 EGG15425.1 - 7.7 6.6 10.3 2.8 8.0 0.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1515) RWD PF05773.22 EGG15426.1 - 7.5e-19 68.1 4.3 1.9e-18 66.9 4.3 1.7 1 1 0 1 1 1 1 RWD domain IBR PF01485.21 EGG15426.1 - 2.7e-09 37.1 23.9 2.7e-06 27.5 9.1 5.5 3 1 2 5 5 5 4 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EGG15426.1 - 0.0018 18.2 7.6 0.0018 18.2 7.6 4.6 4 1 0 4 4 4 1 RING-type zinc-finger Sec61_beta PF03911.16 EGG15427.1 - 7.6e-17 61.1 0.3 1.1e-16 60.6 0.3 1.3 1 0 0 1 1 1 1 Sec61beta family Golgin_A5 PF09787.9 EGG15427.1 - 0.37 10.2 0.4 0.37 10.2 0.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 ANAPC4_WD40 PF12894.7 EGG15428.1 - 1.7e-11 44.2 2.6 8.3e-05 22.8 0.1 3.9 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG15428.1 - 1.3e-10 41.7 19.0 0.0019 19.0 0.7 6.0 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.11 EGG15428.1 - 6.4e-06 26.2 3.7 0.021 14.7 0.1 4.7 3 1 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A B_solenoid_dext PF18841.1 EGG15428.1 - 0.081 13.2 0.1 8.6 6.8 0.0 3.2 3 0 0 3 3 3 0 Beta solenoid repeat from Dextranase DPPIV_N PF00930.21 EGG15428.1 - 0.15 10.8 3.6 0.84 8.3 1.2 2.8 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region RabGAP-TBC PF00566.18 EGG15430.1 - 0.00066 19.4 4.8 0.0011 18.7 3.9 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain NUDE_C PF04880.13 EGG15430.1 - 0.005 17.3 2.0 0.011 16.2 2.0 1.5 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region Ripply PF14998.6 EGG15433.1 - 0.14 12.8 0.0 0.15 12.7 0.0 1.1 1 0 0 1 1 1 0 Transcription Regulator Atx10homo_assoc PF09759.9 EGG15434.1 - 1.5e-15 57.0 6.0 0.0023 17.9 0.2 5.9 1 1 5 6 6 6 5 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EGG15434.1 - 5.3e-15 54.9 1.0 0.0045 17.0 0.0 7.1 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat F-box-like PF12937.7 EGG15434.1 - 0.00075 19.4 1.1 0.0011 18.8 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGG15434.1 - 0.27 11.2 2.8 0.2 11.6 0.3 2.2 2 0 0 2 2 2 0 F-box domain ANAPC8 PF04049.13 EGG15435.1 - 0.31 11.1 3.6 1.3 9.1 0.4 2.3 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 Es2 PF09751.9 EGG15436.1 - 2.1e-52 179.3 20.7 6.7e-31 108.5 8.8 3.1 1 1 2 3 3 3 3 Nuclear protein Es2 DUF4727 PF15856.5 EGG15436.1 - 0.014 15.0 0.4 0.027 14.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) DASH_Spc19 PF08287.11 EGG15437.1 - 0.0042 17.0 11.9 0.0042 17.0 11.9 2.8 1 1 2 3 3 3 2 Spc19 FlaC_arch PF05377.11 EGG15437.1 - 0.0043 17.4 12.0 0.048 14.1 3.4 3.1 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) Secretin_N_2 PF07655.13 EGG15437.1 - 0.07 13.7 13.4 0.24 11.9 13.4 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain DUF1515 PF07439.11 EGG15437.1 - 0.14 12.2 5.3 1.7 8.7 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Viral_P18 PF04521.13 EGG15437.1 - 0.22 11.3 2.3 0.31 10.8 1.6 1.5 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein V_ATPase_I PF01496.19 EGG15437.1 - 0.29 9.0 13.4 0.34 8.8 13.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.6 EGG15437.1 - 0.38 11.2 5.9 3 8.3 1.1 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fzo_mitofusin PF04799.13 EGG15437.1 - 1.4 8.4 8.2 1.8 8.1 0.8 2.3 1 1 0 2 2 2 0 fzo-like conserved region KELK PF15796.5 EGG15437.1 - 1.4 9.4 9.7 0.91 10.0 7.3 2.0 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rho_Binding PF08912.11 EGG15437.1 - 4.7 8.1 20.0 0.68 10.8 4.4 3.5 4 0 0 4 4 4 0 Rho Binding Osmo_CC PF08946.10 EGG15437.1 - 6 7.2 7.4 7.1 7.0 0.3 2.9 1 1 2 3 3 3 0 Osmosensory transporter coiled coil Apt1 PF10351.9 EGG15438.1 - 0.014 14.3 9.6 0.022 13.6 9.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 EGG15438.1 - 0.015 14.5 0.4 0.023 13.9 0.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RRM_DME PF15628.6 EGG15438.1 - 0.016 15.4 0.1 0.072 13.3 0.0 2.1 2 0 0 2 2 2 0 RRM in Demeter NPR3 PF03666.13 EGG15438.1 - 0.079 11.7 2.9 0.1 11.3 2.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SPX PF03105.19 EGG15438.1 - 0.079 12.9 12.8 0.12 12.3 12.8 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 EGG15438.1 - 0.38 9.3 14.2 0.65 8.5 14.2 1.3 1 0 0 1 1 1 0 Macoilin family DUF681 PF05080.12 EGG15438.1 - 0.41 11.3 4.1 0.48 11.1 0.2 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF681) SpoIIIAH PF12685.7 EGG15438.1 - 1.6 8.5 10.3 3.1 7.6 10.3 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein RIBIOP_C PF04950.12 EGG15440.1 - 5.4e-82 275.5 0.1 5.4e-82 275.5 0.1 2.8 3 0 0 3 3 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGG15440.1 - 1.2e-30 105.5 0.9 4.6e-30 103.5 0.0 2.7 2 0 0 2 2 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 EGG15440.1 - 4.3e-08 32.9 0.0 3.2e-06 26.8 0.0 2.7 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EGG15440.1 - 8.6e-07 29.2 0.3 2.8e-06 27.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 EGG15440.1 - 3.8e-05 23.8 1.0 0.00023 21.2 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 EGG15440.1 - 0.00051 20.5 0.4 0.0034 17.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG15440.1 - 0.00063 20.2 0.3 0.004 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGG15440.1 - 0.0013 19.0 0.0 0.005 17.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGG15440.1 - 0.0055 17.2 0.0 0.0055 17.2 0.0 3.4 3 1 0 3 3 2 1 ABC transporter PduV-EutP PF10662.9 EGG15440.1 - 0.019 14.7 0.0 0.068 12.9 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Clavanin PF05452.11 EGG15440.1 - 0.021 15.0 0.3 0.063 13.5 0.3 1.8 1 0 0 1 1 1 0 Clavanin RNA_helicase PF00910.22 EGG15440.1 - 0.031 14.7 0.4 0.14 12.6 0.0 2.4 3 0 0 3 3 1 0 RNA helicase cobW PF02492.19 EGG15440.1 - 0.036 13.7 0.0 0.093 12.3 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EGG15440.1 - 0.058 13.3 0.0 0.058 13.3 0.0 2.7 2 1 1 3 3 3 0 RsgA GTPase Ploopntkinase3 PF18751.1 EGG15440.1 - 0.098 12.6 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 FeoB_N PF02421.18 EGG15440.1 - 0.1 12.2 0.8 2.3 7.7 0.1 3.0 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.6 EGG15440.1 - 0.14 12.7 0.0 0.14 12.7 0.0 3.1 3 1 0 3 3 2 0 AAA domain MeaB PF03308.16 EGG15440.1 - 0.23 10.4 0.0 0.23 10.4 0.0 1.7 2 0 0 2 2 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCU PF04678.13 EGG15440.1 - 2.8 8.0 5.5 11 6.0 5.5 2.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter SecE PF00584.20 EGG15441.1 - 1.3e-10 41.0 3.7 5.5e-06 26.2 0.8 2.1 2 0 0 2 2 2 2 SecE/Sec61-gamma subunits of protein translocation complex Actin PF00022.19 EGG15442.1 - 6.3e-29 100.8 1.2 8.5e-24 83.9 0.1 3.1 2 2 0 2 2 2 2 Actin FtsA PF14450.6 EGG15442.1 - 0.0036 17.7 0.7 0.45 11.0 0.0 2.8 3 0 0 3 3 3 1 Cell division protein FtsA Fungal_trans_2 PF11951.8 EGG15442.1 - 0.11 11.3 2.8 0.17 10.7 1.1 2.0 2 0 0 2 2 2 0 Fungal specific transcription factor domain PH_RBD PF12068.8 EGG15442.1 - 0.42 10.1 9.6 0.27 10.7 2.8 2.6 2 0 0 2 2 2 0 Rab-binding domain (RBD) GAT PF03127.14 EGG15444.1 - 0.044 14.1 0.3 0.044 14.1 0.3 2.5 3 0 0 3 3 3 0 GAT domain DASH_Dad1 PF08649.10 EGG15444.1 - 0.35 11.1 5.6 1.6 9.0 0.1 3.7 4 0 0 4 4 4 0 DASH complex subunit Dad1 UBA PF00627.31 EGG15445.1 - 1.1e-09 38.0 0.3 2.7e-09 36.7 0.3 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EGF_2 PF07974.13 EGG15445.1 - 0.00037 20.8 33.3 0.034 14.5 11.8 2.7 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGG15445.1 - 0.00068 19.6 22.9 0.02 15.0 8.8 2.5 2 0 0 2 2 2 2 Tenascin EGF domain UBA_3 PF09288.10 EGG15445.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain MMPL PF03176.15 EGG15445.1 - 0.19 10.6 3.2 0.35 9.8 3.2 1.3 1 0 0 1 1 1 0 MMPL family MMM1 PF10296.9 EGG15446.1 - 8.7e-10 38.2 2.6 1.7e-06 27.3 1.6 3.2 2 1 1 3 3 3 2 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 EGG15446.1 - 4.5e-05 23.9 0.9 0.00015 22.2 0.9 2.0 1 0 0 1 1 1 1 PH domain SOG2 PF10428.9 EGG15446.1 - 0.02 14.1 12.3 0.027 13.7 12.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Mucin PF01456.17 EGG15446.1 - 0.072 13.1 17.6 0.14 12.1 17.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Senescence_reg PF04520.13 EGG15446.1 - 0.34 11.8 6.5 0.82 10.5 6.5 1.6 1 0 0 1 1 1 0 Senescence regulator Ribosomal_S30 PF04758.14 EGG15447.1 - 2.9e-26 91.4 9.3 3.3e-26 91.2 9.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 ATP-synt_10 PF05176.14 EGG15449.1 - 2.7e-28 98.9 0.1 3.2e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 ATP10 protein UbiA PF01040.18 EGG15450.1 - 8.5e-29 100.6 11.7 1.1e-28 100.3 11.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family JAMP PF05571.12 EGG15450.1 - 0.0028 17.3 1.6 0.0028 17.3 1.6 1.7 2 0 0 2 2 2 1 JNK1/MAPK8-associated membrane protein E1-E2_ATPase PF00122.20 EGG15450.1 - 2.8 7.4 5.2 1.3 8.5 0.3 2.5 2 1 0 3 3 3 0 E1-E2 ATPase G_glu_transpept PF01019.21 EGG15453.1 - 2.5e-147 491.8 0.0 2.8e-147 491.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DDHD PF02862.17 EGG15454.1 - 1.2e-27 97.5 10.1 1.4e-26 94.1 5.3 2.5 2 0 0 2 2 2 2 DDHD domain DUF202 PF02656.15 EGG15454.1 - 1e-08 35.5 5.5 1e-08 35.5 5.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF676 PF05057.14 EGG15454.1 - 0.0065 16.0 0.1 0.46 9.9 0.0 2.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) CCSMST1 PF15013.6 EGG15454.1 - 0.43 10.8 2.9 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 CCSMST1 family DHR-2 PF06920.13 EGG15455.1 - 4.1e-172 573.5 9.1 7.9e-172 572.6 9.1 1.5 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 EGG15455.1 - 1.3e-44 152.4 1.1 1.5e-43 148.9 0.4 2.6 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Bact_lectin PF18483.1 EGG15455.1 - 2.4e-17 63.6 2.4 2.5e-17 63.6 0.0 2.2 2 0 0 2 2 2 1 Bacterial lectin Lectin_legB PF00139.19 EGG15455.1 - 1.9e-16 60.4 0.0 4.2e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Legume lectin domain Lectin_leg-like PF03388.13 EGG15455.1 - 6.2e-05 22.4 0.1 0.0002 20.8 0.1 1.9 1 1 0 1 1 1 1 Legume-like lectin family Latrotoxin_C PF15658.6 EGG15455.1 - 0.089 12.5 0.5 0.27 11.0 0.5 1.8 1 0 0 1 1 1 0 Latrotoxin C-terminal domain SPX PF03105.19 EGG15456.1 - 0.037 13.9 22.9 0.046 13.6 22.9 1.0 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 EGG15456.1 - 0.25 9.9 23.3 0.27 9.8 23.3 1.0 1 0 0 1 1 1 0 Macoilin family DUF896 PF05979.12 EGG15456.1 - 0.44 10.5 7.2 1.3 8.9 0.3 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Neur_chan_memb PF02932.16 EGG15456.1 - 10 6.1 10.0 12 5.9 10.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dicty_CAD PF05720.12 EGG15458.1 - 2.4e-05 24.2 0.1 3e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Cell-cell adhesion domain Hydrolase_6 PF13344.6 EGG15459.1 - 1.6e-28 98.8 0.0 4e-28 97.5 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGG15459.1 - 3.3e-16 59.1 0.0 8e-16 57.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EGG15459.1 - 8.1e-11 42.6 0.0 1.6e-10 41.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGG15459.1 - 5.4e-07 29.9 0.2 0.0017 18.4 0.0 2.6 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EGG15459.1 - 0.038 13.6 0.5 0.29 10.7 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial PGP phosphatase DUF4985 PF16373.5 EGG15459.1 - 0.17 12.4 0.0 0.59 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function Ank_2 PF12796.7 EGG15460.1 - 7.3e-06 26.5 0.2 0.017 15.7 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG15460.1 - 0.02 15.4 1.9 1.1e+02 3.8 0.1 5.2 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 EGG15460.1 - 0.03 14.9 1.4 52 4.6 0.0 5.1 4 1 1 5 5 5 0 Ankyrin repeats (many copies) GNAT_acetyltran PF12746.7 EGG15461.1 - 0.022 14.3 0.6 0.022 14.3 0.6 2.1 2 0 0 2 2 2 0 GNAT acetyltransferase Bindin PF02084.15 EGG15462.1 - 0.058 13.7 0.1 0.058 13.7 0.1 2.2 1 1 1 2 2 2 0 Bindin PilX_N PF14341.6 EGG15462.1 - 0.14 12.1 3.9 0.44 10.5 3.9 1.9 1 0 0 1 1 1 0 PilX N-terminal DUF3648 PF12364.8 EGG15462.1 - 0.2 11.9 3.0 0.32 11.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3648) SCFA_trans PF02667.14 EGG15462.1 - 0.36 9.8 1.0 0.58 9.1 1.0 1.3 1 0 0 1 1 1 0 Short chain fatty acid transporter SUZ PF12752.7 EGG15462.1 - 0.5 11.2 3.6 0.62 10.9 0.0 2.7 3 0 0 3 3 3 0 SUZ domain Ank_2 PF12796.7 EGG15463.1 - 0.13 12.8 0.1 15 6.3 0.0 3.5 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EGG15463.1 - 0.23 11.4 4.0 0.75 9.8 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) VWA_3 PF13768.6 EGG15467.1 - 1.4e-22 80.3 0.0 2.4e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 EGG15467.1 - 8.4e-21 74.3 0.0 2.7e-20 72.6 0.0 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 EGG15467.1 - 2.3e-10 41.0 0.5 7.1e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGG15467.1 - 9.9e-10 39.0 0.0 3.2e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EGG15467.1 - 0.0015 18.4 0.1 0.01 15.7 0.1 2.4 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 EGG15467.1 - 0.016 14.6 0.0 0.048 13.0 0.0 1.7 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein PWI PF01480.17 EGG15468.1 - 0.064 13.6 0.8 1.7 9.0 0.0 3.2 3 0 0 3 3 3 0 PWI domain INTS5_N PF14837.6 EGG15468.1 - 0.088 12.4 1.9 0.5 9.9 0.1 2.8 3 0 0 3 3 3 0 Integrator complex subunit 5 N-terminus DEAD PF00270.29 EGG15470.1 - 6.3e-45 153.1 0.0 6.3e-45 153.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG15470.1 - 2.7e-24 85.7 0.5 1.4e-23 83.4 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGG15470.1 - 1.5e-16 60.4 0.2 3.1e-16 59.4 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Ndc1_Nup PF09531.10 EGG15470.1 - 0.13 10.9 4.1 0.16 10.7 4.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 EGG15470.1 - 0.35 8.0 14.3 0.42 7.7 14.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOBP PF15279.6 EGG15470.1 - 1.7 9.2 10.7 2.8 8.5 10.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein AAA_22 PF13401.6 EGG15470.1 - 2.4 8.4 6.4 1.4 9.2 0.0 3.3 4 0 0 4 4 4 0 AAA domain Pkinase PF00069.25 EGG15471.1 - 5.1e-30 104.7 0.0 1.3e-29 103.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG15471.1 - 5.1e-18 65.3 0.0 1e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 EGG15471.1 - 5.7e-09 36.5 6.8 0.11 13.4 0.0 5.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG15471.1 - 4e-05 23.8 0.0 7.7 6.9 0.0 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Complex1_LYR PF05347.15 EGG15472.1 - 1.6e-14 53.6 0.2 2.4e-14 53.1 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EGG15472.1 - 0.00083 19.9 0.1 0.001 19.7 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 EGG15472.1 - 0.0024 18.6 0.9 0.0031 18.2 0.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Chromo PF00385.24 EGG15473.1 - 4e-09 36.3 8.3 1.2e-06 28.4 2.3 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 EGG15473.1 - 1.1e-06 28.6 0.8 1.8e-05 24.8 0.1 2.5 2 0 0 2 2 2 1 Chromo shadow domain VirC1 PF07015.11 EGG15473.1 - 0.032 13.5 0.2 0.05 12.9 0.2 1.2 1 0 0 1 1 1 0 VirC1 protein Ndc1_Nup PF09531.10 EGG15473.1 - 0.42 9.2 3.8 0.52 8.9 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sporozoite_P67 PF05642.11 EGG15473.1 - 1.3 7.0 16.8 2.3 6.2 17.1 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DUF4551 PF15087.6 EGG15473.1 - 1.7 7.3 12.4 2.3 6.9 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) WGG PF10273.9 EGG15474.1 - 4.4e-22 78.5 0.2 1.1e-21 77.3 0.2 1.7 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 EGG15474.1 - 0.00071 19.7 0.7 0.0012 19.0 0.7 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain SGT1 PF07093.11 EGG15474.1 - 0.36 9.2 3.6 0.43 9.0 3.6 1.1 1 0 0 1 1 1 0 SGT1 protein PC_rep PF01851.22 EGG15475.1 - 0.13 12.7 0.4 74 4.1 0.1 4.0 4 0 0 4 4 4 0 Proteasome/cyclosome repeat Csm1_N PF18504.1 EGG15475.1 - 0.17 12.3 0.2 0.17 12.3 0.2 7.5 4 1 4 8 8 8 0 Csm1 N-terminal domain DUF3037 PF11236.8 EGG15475.1 - 0.28 11.6 10.4 0.4 11.1 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) zf-C4H2 PF10146.9 EGG15475.1 - 1.1 9.5 36.8 0.037 14.4 17.5 3.7 1 1 2 3 3 3 0 Zinc finger-containing protein DUF501 PF04417.12 EGG15475.1 - 4.3 7.1 6.8 3.8 7.3 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF501) SKA2 PF16740.5 EGG15476.1 - 0.0074 16.1 2.7 0.18 11.6 2.7 2.5 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 2 DUF4407 PF14362.6 EGG15476.1 - 0.92 8.8 6.5 1.6 8.0 6.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tho2 PF11262.8 EGG15476.1 - 0.96 8.6 9.1 0.32 10.2 6.1 1.7 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 XhlA PF10779.9 EGG15476.1 - 1 9.6 7.0 6.7 7.0 0.2 3.5 3 1 0 3 3 3 0 Haemolysin XhlA Seryl_tRNA_N PF02403.22 EGG15476.1 - 1.2 9.4 13.0 0.47 10.7 3.6 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Myc_N PF01056.18 EGG15478.1 - 7.7 6.3 10.7 8.3 6.2 10.7 1.0 1 0 0 1 1 1 0 Myc amino-terminal region DUF4834 PF16118.5 EGG15479.1 - 2 9.5 15.0 2.9 8.9 15.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PRP1_N PF06424.12 EGG15479.1 - 3 8.2 13.7 4.2 7.8 13.7 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal zf-His_Me_endon PF05551.11 EGG15481.1 - 1e-07 32.2 3.4 1e-07 32.2 3.4 3.6 3 0 0 3 3 3 1 Zinc-binding loop region of homing endonuclease zf-His_Me_endon PF05551.11 EGG15482.1 - 3.2e-08 33.8 6.9 3.2e-08 33.8 6.9 2.2 1 1 1 2 2 2 1 Zinc-binding loop region of homing endonuclease CPSF100_C PF13299.6 EGG15482.1 - 1.7 8.8 12.7 3.9 7.6 3.3 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_Rpc4 PF05132.14 EGG15482.1 - 8.9 6.7 17.3 0.83 10.1 0.7 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Drc1-Sld2 PF11719.8 EGG15484.1 - 0.064 12.8 11.9 0.082 12.4 11.9 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein CDC45 PF02724.14 EGG15484.1 - 0.081 11.2 11.7 0.096 11.0 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.11 EGG15484.1 - 0.45 10.5 36.7 0.096 12.7 31.0 2.0 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) AMP-binding PF00501.28 EGG15484.1 - 0.53 8.8 2.8 0.68 8.5 2.8 1.2 1 0 0 1 1 1 0 AMP-binding enzyme SURF2 PF05477.11 EGG15484.1 - 0.69 9.6 14.7 0.057 13.1 9.9 1.6 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) IFT57 PF10498.9 EGG15484.1 - 0.75 8.7 21.9 0.28 10.1 18.2 1.8 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 SDA1 PF05285.12 EGG15484.1 - 0.81 9.0 20.3 0.85 9.0 18.2 1.9 2 0 0 2 2 2 0 SDA1 TFIIF_alpha PF05793.12 EGG15484.1 - 2.9 6.4 23.8 5.7 5.4 23.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BNIP2 PF12496.8 EGG15484.1 - 3 8.3 16.3 7 7.1 0.8 2.4 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PRP1_N PF06424.12 EGG15484.1 - 9.4 6.6 18.1 3 8.2 15.1 1.6 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal zf-His_Me_endon PF05551.11 EGG15485.1 - 4.8e-07 30.0 8.3 4.8e-07 30.0 8.3 2.3 2 1 0 2 2 2 1 Zinc-binding loop region of homing endonuclease BUD22 PF09073.10 EGG15485.1 - 0.00015 21.3 11.7 0.00015 21.3 11.7 2.3 2 0 0 2 2 2 1 BUD22 Cwf_Cwc_15 PF04889.12 EGG15485.1 - 0.001 18.8 13.0 0.001 18.8 13.0 2.2 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Prothymosin PF03247.14 EGG15485.1 - 0.0031 18.0 18.9 0.0031 18.0 18.9 2.3 2 0 0 2 2 2 1 Prothymosin/parathymosin family SDA1 PF05285.12 EGG15485.1 - 0.007 15.8 26.2 0.018 14.5 17.4 2.1 2 0 0 2 2 2 2 SDA1 Mpp10 PF04006.12 EGG15485.1 - 0.079 11.4 25.5 0.048 12.1 17.2 2.1 2 0 0 2 2 2 0 Mpp10 protein CDC45 PF02724.14 EGG15485.1 - 0.65 8.2 25.6 0.025 12.9 15.1 2.0 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.12 EGG15485.1 - 5.1 5.2 33.3 0.95 7.6 22.9 2.2 2 0 0 2 2 2 0 Nop14-like family Sigma70_ner PF04546.13 EGG15485.1 - 7.6 6.4 23.3 0.71 9.7 12.8 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region IFT57 PF10498.9 EGG15485.1 - 8.5 5.2 21.9 0.41 9.6 12.9 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 MCM_bind PF09739.9 EGG15486.1 - 1.6e-180 601.4 13.0 2.1e-180 601.1 13.0 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Methyltrn_RNA_3 PF02598.17 EGG15490.1 - 0.0083 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methyltransferase Tsi6 PF18660.1 EGG15493.1 - 0.0049 16.9 0.3 0.068 13.2 0.1 2.8 2 0 0 2 2 2 1 Tsi6 Peptidase_S49 PF01343.18 EGG15493.1 - 0.042 13.8 0.1 0.082 12.9 0.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 TTRAP PF14203.6 EGG15493.1 - 0.11 12.4 0.5 0.64 10.0 0.2 2.3 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Imm26 PF15428.6 EGG15494.1 - 0.037 14.3 2.7 0.17 12.1 0.6 2.7 2 0 0 2 2 2 0 Immunity protein 26 LPP20 PF02169.16 EGG15495.1 - 3.6 8.0 10.4 12 6.3 8.4 2.8 2 0 0 2 2 2 0 LPP20 lipoprotein CDC27 PF09507.10 EGG15496.1 - 5.5e-18 65.6 47.4 5.5e-18 65.6 47.4 4.3 1 1 2 3 3 3 1 DNA polymerase subunit Cdc27 zf-H2C2_2 PF13465.6 EGG15497.1 - 0.00025 21.3 0.9 0.00025 21.3 0.9 3.2 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 EGG15497.1 - 0.033 14.8 0.2 0.033 14.8 0.2 9.0 8 1 2 10 10 10 0 FOXP coiled-coil domain R3H-assoc PF13902.6 EGG15498.1 - 1.8e-12 47.8 4.8 1.8e-12 47.8 4.8 2.5 2 1 1 3 3 3 1 R3H-associated N-terminal domain R3H PF01424.22 EGG15498.1 - 0.0037 17.2 0.9 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 R3H domain DUF3536 PF12055.8 EGG15498.1 - 0.033 13.5 0.6 0.055 12.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) OrfB_IS605 PF01385.19 EGG15498.1 - 0.58 10.4 7.3 0.15 12.3 1.4 2.4 2 0 0 2 2 2 0 Probable transposase TMP_2 PF06791.13 EGG15499.1 - 0.093 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein EKAL PF17986.1 EGG15499.1 - 0.094 12.8 1.9 0.3 11.1 1.9 1.8 1 0 0 1 1 1 0 EMP3-KAHRP-like N-terminal domain CSN5_C PF18323.1 EGG15499.1 - 1.2 10.0 6.8 2.4 9.1 6.7 2.0 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF948 PF06103.11 EGG15499.1 - 2.1 8.7 8.2 1 9.6 5.6 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec20 PF03908.13 EGG15499.1 - 6.3 6.8 8.2 2.4 8.1 4.5 2.2 1 1 0 2 2 2 0 Sec20 DASH_Hsk3 PF08227.11 EGG15499.1 - 8.2 6.9 11.6 15 6.0 1.2 3.6 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like Ras PF00071.22 EGG15500.1 - 1.3e-102 340.2 0.0 4.1e-50 169.5 0.0 2.5 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGG15500.1 - 9.9e-47 158.1 0.0 2.9e-22 79.1 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RhoGAP PF00620.27 EGG15500.1 - 1.3e-40 138.7 0.5 2.4e-40 137.8 0.5 1.4 1 0 0 1 1 1 1 RhoGAP domain Arf PF00025.21 EGG15500.1 - 1.1e-14 54.3 0.0 8.1e-07 28.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_7 PF12775.7 EGG15500.1 - 0.01 15.3 0.5 3.1 7.3 0.1 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Cutinase PF01083.22 EGG15500.1 - 0.078 12.9 0.1 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Cutinase TniB PF05621.11 EGG15500.1 - 0.094 12.1 0.0 5.1 6.5 0.0 2.7 2 0 0 2 2 2 0 Bacterial TniB protein Band_3_cyto PF07565.13 EGG15500.1 - 1.1 9.0 6.5 0.22 11.3 1.9 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Ras PF00071.22 EGG15502.1 - 5.4e-52 175.7 0.0 6.3e-52 175.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG15502.1 - 1.6e-22 79.9 0.0 2.5e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG15502.1 - 1.5e-07 31.1 0.0 1.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG15502.1 - 0.0011 18.6 0.0 0.0029 17.2 0.0 1.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Glyco_hydro_7 PF00840.20 EGG15505.1 - 1.2e-197 656.9 7.5 1.4e-197 656.7 7.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 rve PF00665.26 EGG15506.1 - 1.1e-10 41.7 0.0 3.1e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.23 EGG15506.1 - 0.015 15.4 8.8 0.15 12.2 1.1 2.5 2 0 0 2 2 2 0 Zinc knuckle LRR_8 PF13855.6 EGG15506.1 - 0.055 13.3 10.8 0.073 12.8 0.4 4.2 2 1 2 4 4 4 0 Leucine rich repeat RVP PF00077.20 EGG15506.1 - 0.061 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.6 EGG15506.1 - 0.35 10.6 5.4 0.067 12.9 0.7 2.1 2 0 0 2 2 2 0 Zinc knuckle LRR_4 PF12799.7 EGG15506.1 - 0.37 11.3 24.1 0.025 15.0 1.5 6.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) zf-CCHC_2 PF13696.6 EGG15506.1 - 2.6 7.9 10.9 0.22 11.3 2.5 2.5 2 0 0 2 2 2 0 Zinc knuckle COMPASS-Shg1 PF05205.12 EGG15506.1 - 3 8.6 5.8 0.84 10.4 0.0 3.1 3 1 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF4315 PF14193.6 EGG15507.1 - 0.067 13.2 0.5 0.22 11.5 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) DUF3932 PF13068.6 EGG15507.1 - 0.29 11.4 2.7 0.33 11.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3932) RVT_1 PF00078.27 EGG15509.1 - 2.9e-14 53.1 0.0 6.1e-14 52.1 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EGG15509.1 - 0.0074 17.0 0.0 0.023 15.4 0.0 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase 2OG-FeII_Oxy_3 PF13640.6 EGG15510.1 - 3e-12 47.3 0.3 9.5e-12 45.7 0.2 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EGG15510.1 - 0.00018 21.8 0.0 0.00033 21.0 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Crystall PF00030.19 EGG15510.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin DpnD-PcfM PF14207.6 EGG15510.1 - 0.077 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 DpnD/PcfM-like protein PUL PF08324.11 EGG15511.1 - 5.8e-42 143.8 2.0 7.5e-42 143.5 2.0 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 EGG15511.1 - 2.3e-41 141.1 0.0 3.7e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EGG15511.1 - 0.004 17.5 0.2 0.017 15.4 0.0 2.0 2 0 0 2 2 2 1 Lecithin retinol acyltransferase DUF4805 PF16063.5 EGG15511.1 - 0.025 13.9 1.2 0.038 13.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) ELMO_CED12 PF04727.13 EGG15512.1 - 2.2e-38 132.1 0.5 9e-38 130.1 0.5 2.2 1 0 0 1 1 1 1 ELMO/CED-12 family TAP42 PF04177.12 EGG15513.1 - 5.3e-71 239.4 1.8 7.7e-71 238.8 1.8 1.2 1 0 0 1 1 1 1 TAP42-like family DUF4680 PF15730.5 EGG15513.1 - 0.03 14.7 2.9 0.065 13.6 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) Ashwin PF15323.6 EGG15513.1 - 1.9 8.5 15.3 1.8 8.5 8.7 2.7 2 0 0 2 2 2 0 Developmental protein FYDLN_acid PF09538.10 EGG15514.1 - 0.049 14.3 8.2 0.06 14.0 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Spt20 PF12090.8 EGG15514.1 - 0.1 12.2 49.1 0.14 11.7 49.1 1.3 1 0 0 1 1 1 0 Spt20 family baeRF_family12 PF18856.1 EGG15514.1 - 0.23 12.1 13.5 0.25 11.9 13.5 1.1 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 BBL5 PF07289.11 EGG15514.1 - 0.24 10.4 13.7 0.25 10.4 13.7 1.0 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein DUF4820 PF16091.5 EGG15514.1 - 0.28 10.5 15.7 0.29 10.5 15.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) AIF_C PF14721.6 EGG15514.1 - 0.39 11.1 14.4 0.48 10.8 14.4 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3675 PF12428.8 EGG15514.1 - 0.39 11.3 6.5 0.46 11.0 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DUF719 PF05334.13 EGG15514.1 - 0.55 10.4 18.4 0.61 10.3 18.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Eapp_C PF10238.9 EGG15514.1 - 0.57 10.3 17.6 0.64 10.1 17.6 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF4628 PF15429.6 EGG15514.1 - 0.91 9.2 18.1 0.96 9.1 18.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) DUF1764 PF08576.10 EGG15514.1 - 0.92 10.4 14.9 1.1 10.2 14.9 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) FmiP_Thoc5 PF09766.9 EGG15514.1 - 0.93 8.7 25.1 0.94 8.7 25.1 1.0 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Host_attach PF10116.9 EGG15514.1 - 1 9.9 14.9 1.1 9.8 14.9 1.1 1 0 0 1 1 1 0 Protein required for attachment to host cells FAM176 PF14851.6 EGG15514.1 - 1.3 8.7 12.4 1.4 8.5 12.4 1.1 1 0 0 1 1 1 0 FAM176 family G0-G1_switch_2 PF15103.6 EGG15514.1 - 1.6 9.2 12.7 2.1 8.8 12.7 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 EIIBC-GUT_N PF03612.14 EGG15514.1 - 1.9 8.2 16.6 2.3 7.9 16.6 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus eIF-3_zeta PF05091.12 EGG15514.1 - 1.9 7.4 25.8 2 7.3 25.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CobT PF06213.12 EGG15514.1 - 2 7.8 27.9 2.2 7.6 27.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DDRGK PF09756.9 EGG15514.1 - 2 8.0 21.9 2.2 7.8 21.9 1.1 1 0 0 1 1 1 0 DDRGK domain DUF3408 PF11888.8 EGG15514.1 - 2.2 8.4 20.3 2.5 8.2 20.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Pex14_N PF04695.13 EGG15514.1 - 2.2 8.9 33.1 2.4 8.8 33.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MMU163 PF17119.5 EGG15514.1 - 2.2 7.4 11.7 2.5 7.2 11.7 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis NARP1 PF12569.8 EGG15514.1 - 2.2 7.1 17.4 2.3 7.0 17.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TFB6 PF17110.5 EGG15514.1 - 2.3 8.0 10.9 2.4 7.9 10.9 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF3464 PF11947.8 EGG15514.1 - 2.5 7.9 18.3 3 7.6 18.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Connexin PF00029.19 EGG15514.1 - 2.8 7.6 15.9 3 7.5 15.9 1.1 1 0 0 1 1 1 0 Connexin DUF4746 PF15928.5 EGG15514.1 - 2.9 7.2 14.4 3.1 7.1 14.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Endostatin PF06482.11 EGG15514.1 - 3.4 7.0 24.1 3.4 7.0 24.1 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin FAM60A PF15396.6 EGG15514.1 - 3.4 7.6 16.9 4 7.4 16.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SMYLE_N PF18615.1 EGG15514.1 - 3.6 7.1 15.7 3.8 7.0 15.7 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SpoIIP PF07454.11 EGG15514.1 - 3.7 6.9 23.5 3.8 6.9 23.5 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TCP PF03634.13 EGG15514.1 - 3.8 8.1 21.7 4.1 8.0 21.7 1.1 1 0 0 1 1 1 0 TCP family transcription factor RR_TM4-6 PF06459.12 EGG15514.1 - 3.9 7.2 23.3 4.2 7.1 23.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 EGG15514.1 - 4 6.1 19.8 4.4 6.0 19.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.14 EGG15514.1 - 4.1 5.6 16.8 4.1 5.6 16.8 1.0 1 0 0 1 1 1 0 CDC45-like protein EOS1 PF12326.8 EGG15514.1 - 4.2 7.3 15.0 4.5 7.2 15.0 1.1 1 0 0 1 1 1 0 N-glycosylation protein MDM31_MDM32 PF08118.11 EGG15514.1 - 4.5 5.8 14.4 4.6 5.8 14.4 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Serinc PF03348.15 EGG15514.1 - 4.5 6.1 14.5 4.7 6.0 14.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Paf1 PF03985.13 EGG15514.1 - 4.8 6.1 22.1 5.1 6.0 22.1 1.0 1 0 0 1 1 1 0 Paf1 DUF4770 PF15994.5 EGG15514.1 - 4.9 7.4 19.1 6 7.1 19.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Peptidase_S49_N PF08496.10 EGG15514.1 - 4.9 7.2 14.5 5.8 7.0 14.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TERB2 PF15101.6 EGG15514.1 - 5.1 7.1 27.3 5.3 7.0 27.3 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RICTOR_N PF14664.6 EGG15514.1 - 5.8 5.8 12.3 7.1 5.5 12.3 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF2828 PF11443.8 EGG15514.1 - 5.8 4.9 20.4 5.9 4.8 20.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Pal1 PF08316.11 EGG15514.1 - 5.9 7.6 12.4 6.9 7.4 12.4 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF702 PF05142.12 EGG15514.1 - 6.3 7.3 19.0 7.9 6.9 19.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) CPSF100_C PF13299.6 EGG15514.1 - 6.3 6.9 18.0 6.5 6.9 18.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Folate_carrier PF01770.18 EGG15514.1 - 6.3 5.4 12.4 6.1 5.5 12.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier MAJIN PF15077.6 EGG15514.1 - 6.4 6.5 19.0 6.6 6.4 19.0 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Peptidase_U57 PF05582.12 EGG15514.1 - 6.4 5.9 13.5 6.8 5.9 13.5 1.0 1 0 0 1 1 1 0 YabG peptidase U57 PPL5 PF18168.1 EGG15514.1 - 6.6 5.9 14.1 7.2 5.8 14.1 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S15 PF02129.18 EGG15514.1 - 7.1 6.1 16.6 7.8 6.0 16.6 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) YABBY PF04690.13 EGG15514.1 - 7.6 7.1 16.3 8.5 6.9 16.3 1.1 1 0 0 1 1 1 0 YABBY protein CCDC53 PF10152.9 EGG15514.1 - 7.8 6.9 23.1 8.7 6.7 23.1 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FHIPEP PF00771.20 EGG15514.1 - 7.8 4.8 11.7 7.2 4.9 11.7 1.1 1 0 0 1 1 1 0 FHIPEP family PIP5K PF01504.18 EGG15514.1 - 8.6 5.5 17.2 9.4 5.4 17.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase V_ATPase_I PF01496.19 EGG15514.1 - 8.8 4.1 23.3 8.6 4.1 23.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DcuA_DcuB PF03605.14 EGG15514.1 - 8.8 5.1 6.8 11 4.8 6.8 1.3 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Presenilin PF01080.17 EGG15514.1 - 8.9 5.0 27.5 8.8 5.0 27.5 1.0 1 0 0 1 1 1 0 Presenilin DUF2126 PF09899.9 EGG15514.1 - 9.8 4.1 17.3 11 4.0 17.3 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Romo1 PF10247.9 EGG15517.1 - 1.3e-17 63.9 16.0 1.7e-17 63.5 16.0 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 EGG15517.1 - 0.43 11.0 6.4 1.2 9.6 6.4 1.7 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family FMN_red PF03358.15 EGG15518.1 - 1.9e-23 82.9 0.0 2.8e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGG15518.1 - 0.0016 18.1 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Ank_2 PF12796.7 EGG15519.1 - 3.3e-08 34.0 0.2 6e-05 23.5 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG15519.1 - 2.3e-07 30.9 4.6 0.015 15.6 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG15519.1 - 0.0012 19.4 0.2 0.32 11.6 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG15519.1 - 0.0018 18.6 0.0 18 6.3 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 EGG15520.1 - 2.4e-27 95.3 22.3 6e-08 33.2 0.2 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG15520.1 - 3.8e-27 94.3 6.5 2.9e-06 27.7 0.0 7.8 2 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG15520.1 - 6.8e-21 74.1 4.4 0.0016 18.7 0.0 9.5 3 3 8 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG15520.1 - 2.2e-18 64.4 0.1 2.9 8.7 0.0 10.1 9 1 1 10 10 10 5 Ankyrin repeat Ank PF00023.30 EGG15520.1 - 5e-06 26.7 0.8 68 4.2 0.0 7.2 4 2 2 6 6 6 0 Ankyrin repeat DUF3447 PF11929.8 EGG15520.1 - 0.00012 21.9 3.3 0.095 12.7 0.3 4.7 1 1 4 5 5 5 2 Domain of unknown function (DUF3447) DUF5049 PF16468.5 EGG15520.1 - 0.0013 18.6 1.6 49 3.9 0.0 6.2 6 1 2 8 8 8 0 Domain of unknown function (DUF5049) DUF1843 PF08898.10 EGG15520.1 - 0.017 15.6 0.1 59 4.3 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) DUF249 PF03158.13 EGG15520.1 - 0.019 14.7 1.8 0.11 12.3 1.2 2.6 2 1 0 2 2 2 0 Multigene family 530 protein HTH_22 PF13309.6 EGG15520.1 - 0.075 13.1 0.2 5.5 7.1 0.0 3.7 3 1 2 5 5 5 0 HTH domain VHL_C PF17211.3 EGG15520.1 - 0.14 12.2 0.0 21 5.2 0.0 3.8 5 0 0 5 5 5 0 VHL box domain TFIIA PF03153.13 EGG15521.1 - 0.19 11.7 11.0 0.28 11.1 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2489 PF10675.9 EGG15521.1 - 0.2 11.6 4.8 0.37 10.7 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) FAD_binding_3 PF01494.19 EGG15522.1 - 1.2e-17 64.2 0.0 8.2e-17 61.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EGG15522.1 - 1.6e-05 25.4 0.0 0.09 13.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGG15522.1 - 0.00059 19.2 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EGG15522.1 - 0.008 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EGG15522.1 - 0.093 12.4 0.2 0.47 10.1 0.1 2.0 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA Dynein_IC2 PF11540.8 EGG15522.1 - 9.8 6.2 9.9 5.4 7.1 5.6 2.4 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 FAD_binding_3 PF01494.19 EGG15523.1 - 2.9e-18 66.2 0.0 9.7e-18 64.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EGG15523.1 - 9.1e-06 26.1 0.0 0.065 13.8 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGG15523.1 - 0.00043 19.6 0.0 0.78 8.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EGG15523.1 - 0.0071 15.7 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EGG15523.1 - 0.11 12.2 0.2 0.57 9.8 0.1 2.0 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 EGG15523.1 - 0.14 10.8 0.1 4.1 6.0 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Dynein_IC2 PF11540.8 EGG15523.1 - 2.1 8.3 5.6 5.4 7.1 5.6 1.7 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 DUF3439 PF11921.8 EGG15524.1 - 0.22 11.5 4.6 0.38 10.7 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF1955 PF09205.10 EGG15524.1 - 0.43 10.3 3.5 0.28 10.9 0.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1955) Ank_2 PF12796.7 EGG15525.1 - 9.3e-10 39.0 8.4 0.0036 17.9 0.3 6.9 6 1 0 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG15525.1 - 4.6e-05 23.5 4.3 17 6.4 0.0 7.7 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 EGG15525.1 - 0.0001 22.8 8.3 29 5.4 0.0 7.4 6 2 1 7 7 7 1 Ankyrin repeats (many copies) PRP1_N PF06424.12 EGG15525.1 - 0.029 14.7 0.7 0.029 14.7 0.7 3.3 4 0 0 4 4 4 0 PRP1 splicing factor, N-terminal FMN_red PF03358.15 EGG15526.1 - 8.3e-23 80.8 0.0 1.3e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase BPS1 PF05633.11 EGG15526.1 - 0.065 12.2 1.3 5 6.0 0.9 2.1 2 0 0 2 2 2 0 Protein BYPASS1-related FNIP PF05725.12 EGG15527.1 - 2.2e-25 88.5 38.5 3.5e-05 23.9 1.9 11.8 9 4 1 10 10 10 8 FNIP Repeat LRR_4 PF12799.7 EGG15527.1 - 0.13 12.8 11.2 5.6 7.5 0.1 5.3 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) FNIP PF05725.12 EGG15528.1 - 9.6e-52 172.9 76.2 8.1e-10 38.7 0.5 13.9 11 3 4 16 16 16 11 FNIP Repeat Pkinase PF00069.25 EGG15528.1 - 4.2e-32 111.6 5.3 3.4e-23 82.3 3.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG15528.1 - 4.7e-14 52.3 1.5 3.3e-06 26.6 0.1 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGG15528.1 - 0.0002 20.8 0.0 0.27 10.5 0.0 2.6 2 0 0 2 2 2 2 Kinase-like Ank_4 PF13637.6 EGG15531.1 - 8.8e-14 51.7 1.0 0.0023 18.5 0.0 5.1 4 2 0 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG15531.1 - 2.8e-12 47.1 10.7 5.9e-06 26.8 0.4 4.8 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG15531.1 - 2.9e-10 40.2 1.5 0.033 14.5 0.0 5.9 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG15531.1 - 2.7e-07 30.4 3.6 2.3 9.1 0.0 6.9 8 0 0 8 8 8 2 Ankyrin repeat Dabb PF07876.12 EGG15532.1 - 2.2e-14 53.9 0.0 9.4e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 Stress responsive A/B Barrel Domain NAD_kinase PF01513.21 EGG15533.1 - 1.8e-64 217.8 0.0 3.4e-64 216.9 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase CD20 PF04103.15 EGG15533.1 - 0.85 9.7 8.5 0.079 13.0 0.4 2.9 3 0 0 3 3 3 0 CD20-like family CobT PF06213.12 EGG15533.1 - 1.1 8.6 5.0 2.1 7.6 5.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Conotoxin PF02950.17 EGG15533.1 - 8.6 7.5 16.3 0.55 11.3 4.6 3.0 2 0 0 2 2 2 0 Conotoxin ubiquitin PF00240.23 EGG15534.1 - 1.7e-135 441.0 17.6 3.8e-33 113.1 0.4 4.1 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EGG15534.1 - 4.3e-62 205.9 18.0 8.4e-15 54.4 0.4 4.1 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGG15534.1 - 2.5e-22 79.1 7.4 0.00097 19.5 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EGG15534.1 - 1.6e-14 53.6 2.6 0.091 12.7 0.0 4.3 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGG15534.1 - 3e-14 53.1 7.6 0.054 13.9 0.1 4.3 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGG15534.1 - 2.3e-13 50.2 1.7 0.24 11.5 0.0 4.9 4 3 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGG15534.1 - 8.6e-12 45.5 0.6 0.71 10.5 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGG15534.1 - 3e-06 27.2 0.1 6 6.7 0.0 4.1 1 1 3 4 4 4 1 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 EGG15534.1 - 4.1e-06 26.3 1.6 1.7 7.9 0.0 3.4 4 0 0 4 4 4 3 RNA methyltransferase DUF2870 PF11069.8 EGG15534.1 - 5.2e-06 26.8 0.1 17 5.9 0.0 5.1 4 4 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 EGG15534.1 - 0.00016 21.5 2.1 32 4.5 0.0 4.4 4 0 0 4 4 4 0 ACT domain UDP-g_GGTase PF06427.11 EGG15534.1 - 0.00024 21.2 3.6 9.6 6.4 0.0 4.1 5 0 0 5 5 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF3861 PF12977.7 EGG15534.1 - 0.0004 20.5 1.5 54 4.1 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Ubiquitin_4 PF18036.1 EGG15534.1 - 0.00049 20.1 28.2 33 4.6 0.0 8.4 9 0 0 9 9 8 0 Ubiquitin-like domain DUF969 PF06149.12 EGG15534.1 - 0.00057 19.4 0.0 30 3.9 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) Big_7 PF17957.1 EGG15534.1 - 0.0011 19.7 0.0 1.3e+02 3.5 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain Corona_NS2A PF05213.12 EGG15534.1 - 0.0033 16.8 0.0 37 3.6 0.0 4.0 4 0 0 4 4 4 0 Coronavirus NS2A protein ACT_4 PF13291.6 EGG15534.1 - 0.0035 17.9 0.2 1.5e+02 3.0 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF3435 PF11917.8 EGG15534.1 - 0.0062 15.5 0.4 48 2.7 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3435) ORF11CD3 PF10549.9 EGG15534.1 - 0.012 15.7 0.0 1.2e+02 2.9 0.0 4.5 4 0 0 4 4 4 0 ORF11CD3 domain PTS-HPr PF00381.19 EGG15534.1 - 0.058 13.6 1.3 2.1e+02 2.2 0.0 4.2 4 0 0 4 4 4 0 PTS HPr component phosphorylation site Imm12 PF15560.6 EGG15534.1 - 0.14 12.1 5.3 1.1e+02 2.8 0.0 4.4 5 0 0 5 5 5 0 Immunity protein 12 ProRS-C_2 PF09181.10 EGG15534.1 - 0.28 11.4 5.2 1.5e+02 2.6 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal YcgR_2 PF12945.7 EGG15534.1 - 0.66 10.2 4.8 2.1e+02 2.1 0.1 4.2 4 0 0 4 4 4 0 Flagellar protein YcgR PH_15 PF17339.2 EGG15534.1 - 4.6 7.2 7.3 96 2.9 0.1 4.0 5 0 0 5 5 5 0 PH domain FlgD_ig PF13860.6 EGG15534.1 - 4.8 7.1 8.0 1.8e+02 2.1 0.1 4.2 4 0 0 4 4 4 0 FlgD Ig-like domain Ras PF00071.22 EGG15537.1 - 2.4e-57 193.0 0.0 3.2e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG15537.1 - 1.2e-23 83.6 0.0 2.1e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG15537.1 - 1.2e-08 34.6 0.0 1.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PT PF04886.12 EGG15538.1 - 0.022 14.3 0.7 0.092 12.3 0.7 2.1 1 1 0 1 1 1 0 PT repeat BAR_3 PF16746.5 EGG15539.1 - 2e-20 73.5 11.8 4.1e-20 72.5 11.8 1.4 1 0 0 1 1 1 1 BAR domain of APPL family Ank_4 PF13637.6 EGG15539.1 - 7.5e-12 45.5 0.2 6.3e-07 29.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) BAR PF03114.18 EGG15539.1 - 1.9e-10 40.8 9.3 1.9e-10 40.8 9.3 1.7 2 0 0 2 2 1 1 BAR domain Ank_2 PF12796.7 EGG15539.1 - 1e-09 38.8 0.0 4.3e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG15539.1 - 2.3e-09 37.3 0.1 7.1e-09 35.8 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PH PF00169.29 EGG15539.1 - 1.3e-06 28.9 0.5 4.4e-06 27.1 0.5 2.0 1 0 0 1 1 1 1 PH domain Ank PF00023.30 EGG15539.1 - 2.1e-06 27.9 0.1 0.088 13.3 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EGG15539.1 - 0.0092 16.4 0.0 0.15 12.7 0.0 2.8 3 0 0 3 3 2 1 Ankyrin repeat PH_9 PF15410.6 EGG15539.1 - 0.13 12.6 0.8 2.6 8.4 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 EGG15539.1 - 3.8 8.0 10.2 0.16 12.4 0.3 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain DUF3915 PF13054.6 EGG15539.1 - 4 7.4 7.8 0.36 10.8 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Endotoxin_N PF03945.14 EGG15540.1 - 3.2e-08 33.6 0.0 0.00055 19.7 0.0 2.8 3 0 0 3 3 3 2 delta endotoxin, N-terminal domain FancD2 PF14631.6 EGG15540.1 - 0.0017 15.8 0.0 0.94 6.8 0.0 2.1 2 0 0 2 2 2 2 Fanconi anaemia protein FancD2 nuclease DUF3037 PF11236.8 EGG15540.1 - 0.0018 18.7 0.1 3.2 8.2 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3037) MSP7_C PF12948.7 EGG15540.1 - 0.005 17.5 0.0 5.1 7.8 0.0 2.6 2 0 0 2 2 2 2 MSP7-like protein C-terminal domain DUF515 PF04415.12 EGG15540.1 - 0.017 13.5 1.9 0.029 12.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PGM_PMM_II PF02879.16 EGG15540.1 - 0.019 15.6 0.0 3.3 8.4 0.0 2.7 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SR-25 PF10500.9 EGG15540.1 - 0.021 14.5 10.6 0.035 13.7 10.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SurA_N_2 PF13623.6 EGG15540.1 - 0.036 13.9 2.0 5.4 6.9 0.2 2.5 2 0 0 2 2 2 0 SurA N-terminal domain Plus-3 PF03126.18 EGG15540.1 - 0.12 12.9 2.8 9.6 6.8 0.2 2.5 2 0 0 2 2 2 0 Plus-3 domain CLU PF13236.6 EGG15540.1 - 0.15 11.8 0.1 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Clustered mitochondria DUF4059 PF13268.6 EGG15540.1 - 0.24 11.8 1.5 29 5.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) FoP_duplication PF13865.6 EGG15540.1 - 0.28 11.7 1.8 27 5.4 0.2 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 IMUP PF15761.5 EGG15540.1 - 1.6 9.5 7.2 3.1 8.5 7.2 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF5470 PF17564.2 EGG15540.1 - 3.5 7.9 7.4 7.6 6.8 7.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5470) DUF2873 PF11395.8 EGG15540.1 - 7.4 6.5 7.2 29 4.6 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) Endotoxin_N PF03945.14 EGG15541.1 - 2.6e-05 24.0 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain DUF3037 PF11236.8 EGG15541.1 - 0.0078 16.6 0.0 0.02 15.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3037) MSP7_C PF12948.7 EGG15541.1 - 0.048 14.3 0.0 0.088 13.5 0.0 1.4 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain Endotoxin_N PF03945.14 EGG15542.1 - 0.0032 17.2 4.5 0.0055 16.5 4.5 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Xlink PF00193.17 EGG15542.1 - 0.053 13.9 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Extracellular link domain MFS_1 PF07690.16 EGG15543.1 - 2.8e-28 98.9 26.3 3.4e-28 98.6 25.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 EGG15543.1 - 8.1e-07 27.8 7.6 0.0028 16.1 0.4 2.0 2 0 0 2 2 2 2 Transmembrane secretion effector Sugar_tr PF00083.24 EGG15543.1 - 0.0011 17.9 5.2 0.0011 17.9 5.2 3.2 2 2 1 3 3 3 2 Sugar (and other) transporter ETRAMP PF09716.10 EGG15543.1 - 0.17 11.9 0.6 0.87 9.7 0.0 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) zf-TRAF PF02176.18 EGG15544.1 - 2.8e-05 24.7 13.4 2.8e-05 24.7 13.4 5.0 3 2 1 4 4 4 2 TRAF-type zinc finger zf-RING-like PF08746.11 EGG15544.1 - 0.0097 16.2 8.3 0.0097 16.2 8.3 3.8 3 1 1 4 4 4 1 RING-like domain FKS1_dom1 PF14288.6 EGG15544.1 - 0.035 14.4 0.4 0.11 12.9 0.4 1.8 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Mto2_bdg PF12808.7 EGG15544.1 - 0.41 11.0 2.2 1.6 9.0 0.6 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TatD_DNase PF01026.21 EGG15545.1 - 1.2e-42 146.1 0.0 1.9e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Roughex PF06020.11 EGG15546.1 - 1.1 8.2 10.3 1.8 7.6 10.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Nop14 PF04147.12 EGG15546.1 - 1.2 7.3 13.2 1.6 6.9 13.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGG15546.1 - 2.5 6.3 12.8 3.6 5.8 12.8 1.2 1 0 0 1 1 1 0 CDC45-like protein ATG16 PF08614.11 EGG15547.1 - 4e-45 154.5 18.6 5.2e-45 154.1 18.6 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 EGG15547.1 - 5.3e-34 115.7 27.8 2e-06 28.4 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG15547.1 - 1.3e-12 47.8 2.6 0.024 15.0 0.0 6.4 4 2 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG15547.1 - 0.0012 18.3 0.4 0.01 15.2 0.0 2.7 4 0 0 4 4 4 1 WD40-like domain KASH_CCD PF14662.6 EGG15547.1 - 0.0014 18.5 11.5 0.0014 18.5 11.5 2.0 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH PALB2_WD40 PF16756.5 EGG15547.1 - 0.0041 16.1 1.1 0.92 8.4 0.2 3.3 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain DUF4407 PF14362.6 EGG15547.1 - 0.015 14.7 8.4 0.022 14.1 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SRP54_N PF02881.19 EGG15547.1 - 0.056 13.7 1.2 0.13 12.5 1.2 1.6 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain Macoilin PF09726.9 EGG15547.1 - 7.1 5.1 18.2 8 4.9 17.4 1.4 1 1 0 1 1 1 0 Macoilin family Fez1 PF06818.15 EGG15547.1 - 9.1 6.7 19.7 3.2 8.2 10.9 2.2 1 1 1 2 2 2 0 Fez1 SNARE_assoc PF09335.11 EGG15548.1 - 4.1e-22 78.9 5.9 4.1e-22 78.9 5.9 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF1772 PF08592.11 EGG15548.1 - 6.1e-05 23.3 0.7 0.0059 16.9 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) FAM176 PF14851.6 EGG15548.1 - 0.0053 16.4 0.3 0.0053 16.4 0.3 2.2 2 0 0 2 2 2 1 FAM176 family TMEM132D_C PF15706.5 EGG15548.1 - 0.0056 16.4 6.5 0.5 10.2 0.0 3.8 3 0 0 3 3 3 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Protocadherin PF08374.11 EGG15548.1 - 0.018 15.0 5.9 0.019 14.9 0.1 2.3 2 0 0 2 2 2 0 Protocadherin DUF2070 PF09843.9 EGG15548.1 - 1.4 7.2 13.4 2.3 6.4 13.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5345 PF17280.2 EGG15548.1 - 5.7 7.0 9.2 0.42 10.6 0.3 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5345) NAD_binding_6 PF08030.12 EGG15549.1 - 2.6e-31 108.9 2.3 4e-31 108.2 0.1 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGG15549.1 - 3.4e-21 75.7 7.9 3.4e-21 75.7 7.9 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGG15549.1 - 1e-18 67.4 0.0 2.9e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 EGG15549.1 - 0.00086 19.6 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGG15549.1 - 0.049 14.3 0.1 4.7 7.9 0.0 2.9 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain Ribosomal_L27A PF00828.19 EGG15550.1 - 3.2e-21 76.3 0.0 4.2e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5026 PF16429.5 EGG15550.1 - 0.15 12.2 0.4 0.27 11.4 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) BPS1 PF05633.11 EGG15551.1 - 0.011 14.7 0.2 0.02 13.9 0.2 1.3 1 0 0 1 1 1 0 Protein BYPASS1-related SLATT_6 PF18169.1 EGG15552.1 - 0.059 13.0 3.1 6.5 6.3 0.1 3.7 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 PRIMA1 PF16101.5 EGG15553.1 - 0.019 15.0 1.5 0.042 13.9 1.5 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TAFH PF07531.14 EGG15557.1 - 0.04 14.0 0.1 0.058 13.5 0.1 1.3 1 0 0 1 1 1 0 NHR1 homology to TAF Menin PF05053.13 EGG15562.1 - 1 7.6 11.5 1.6 7.0 11.5 1.2 1 0 0 1 1 1 0 Menin UvrB_inter PF17757.1 EGG15563.1 - 0.051 13.8 1.0 21 5.4 0.0 3.5 3 1 1 4 4 4 0 UvrB interaction domain Mu-like_Pro PF10123.9 EGG15565.1 - 0.0066 16.0 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Mu-like prophage I protein RTTN_N PF14726.6 EGG15565.1 - 0.011 16.6 5.4 0.049 14.4 0.7 3.4 2 1 1 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning DUF1796 PF08795.10 EGG15566.1 - 0.15 12.1 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Dicty_CAD PF05720.12 EGG15567.1 - 2.1e-32 110.9 0.1 2.6e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 Cell-cell adhesion domain EGF_2 PF07974.13 EGG15568.1 - 0.0052 17.1 10.9 0.0052 17.1 10.9 2.1 2 0 0 2 2 2 1 EGF-like domain fn3 PF00041.21 EGG15568.1 - 0.042 14.2 0.1 0.042 14.2 0.1 5.3 5 0 0 5 5 5 0 Fibronectin type III domain EGF_Tenascin PF18720.1 EGG15568.1 - 0.76 9.9 5.7 2.3 8.4 5.7 1.8 1 0 0 1 1 1 0 Tenascin EGF domain Endotoxin_N PF03945.14 EGG15569.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain DUF3213 PF11491.8 EGG15569.1 - 0.2 11.8 0.6 0.42 10.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) BEN PF10523.9 EGG15570.1 - 0.0036 17.5 2.6 0.028 14.6 0.9 3.0 3 0 0 3 3 3 1 BEN domain LSM PF01423.22 EGG15571.1 - 2.3e-17 62.4 0.5 3.1e-17 62.0 0.5 1.2 1 0 0 1 1 1 1 LSM domain Prenyltrans PF00432.21 EGG15572.1 - 1.3e-42 143.2 9.4 5.2e-11 42.1 0.3 5.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat ubiquitin PF00240.23 EGG15572.1 - 6.2e-09 35.5 0.1 2e-06 27.4 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin family ubiquitin PF00240.23 EGG15573.1 - 3.9e-166 539.1 27.6 1.1e-32 111.5 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 EGG15573.1 - 4.4e-77 253.9 26.9 8.3e-15 54.4 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGG15573.1 - 4.7e-27 94.3 14.3 0.00093 19.6 0.1 7.0 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 EGG15573.1 - 8.6e-18 64.1 7.1 0.085 12.8 0.0 5.3 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGG15573.1 - 1.4e-17 63.8 11.5 0.061 13.7 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGG15573.1 - 2e-16 60.1 3.9 0.29 11.2 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGG15573.1 - 1.8e-15 57.4 1.6 0.66 10.6 0.0 5.2 1 1 2 5 5 5 5 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 EGG15573.1 - 3.5e-08 33.0 2.1 2.3 7.5 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase DUF2870 PF11069.8 EGG15573.1 - 1.6e-07 31.6 0.0 40 4.7 0.0 5.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) Ubiquitin_4 PF18036.1 EGG15573.1 - 5.1e-07 29.7 29.5 34 4.6 0.0 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain Big_3_3 PF13750.6 EGG15573.1 - 7e-07 29.0 0.1 27 4.4 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) DUF969 PF06149.12 EGG15573.1 - 1.4e-05 24.6 0.1 28 4.1 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF969) DUF3861 PF12977.7 EGG15573.1 - 1.5e-05 25.1 3.3 48 4.2 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) UDP-g_GGTase PF06427.11 EGG15573.1 - 1.7e-05 24.9 7.8 9.6 6.4 0.1 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF3435 PF11917.8 EGG15573.1 - 5.5e-05 22.3 1.1 30 3.4 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3435) Big_7 PF17957.1 EGG15573.1 - 6.6e-05 23.6 0.2 1.5e+02 3.3 0.0 5.0 5 0 0 5 5 5 0 Bacterial Ig domain Corona_NS2A PF05213.12 EGG15573.1 - 0.0002 20.8 0.1 58 2.9 0.0 4.8 5 0 0 5 5 5 0 Coronavirus NS2A protein ACT_5 PF13710.6 EGG15573.1 - 0.00046 20.0 5.7 56 3.7 0.0 5.2 5 0 0 5 5 5 0 ACT domain ORF11CD3 PF10549.9 EGG15573.1 - 0.00056 20.0 1.8 1.2e+02 2.9 0.0 6.3 10 0 0 10 10 5 0 ORF11CD3 domain YcgR_2 PF12945.7 EGG15573.1 - 0.00074 19.6 10.3 40 4.4 0.1 5.2 5 0 0 5 5 5 0 Flagellar protein YcgR ACT_4 PF13291.6 EGG15573.1 - 0.0017 18.9 0.7 2.4e+02 2.4 0.0 5.0 5 0 0 5 5 5 0 ACT domain Imm12 PF15560.6 EGG15573.1 - 0.0026 17.7 3.6 1e+02 2.9 0.0 4.9 5 0 0 5 5 5 0 Immunity protein 12 NEAT PF05031.12 EGG15573.1 - 0.036 14.7 8.8 22 5.7 0.6 4.5 1 1 3 4 4 4 0 Iron Transport-associated domain Glyco_tran_WecB PF03808.13 EGG15573.1 - 0.074 13.0 0.0 2.7e+02 1.4 0.0 4.3 5 0 0 5 5 5 0 Glycosyl transferase WecB/TagA/CpsF family ProRS-C_2 PF09181.10 EGG15573.1 - 2.8 8.1 9.1 2.6e+02 1.8 0.1 4.8 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal PH_15 PF17339.2 EGG15573.1 - 7.8 6.5 10.9 1.2e+02 2.7 0.1 4.4 5 0 0 5 5 5 0 PH domain SelP_N PF04592.14 EGG15575.1 - 0.063 12.7 34.5 0.14 11.5 34.5 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Connexin PF00029.19 EGG15575.1 - 0.13 12.0 4.6 0.21 11.3 4.6 1.3 1 0 0 1 1 1 0 Connexin SSP160 PF06933.11 EGG15575.1 - 0.27 9.4 30.7 0.19 9.9 29.1 1.4 1 1 0 1 1 1 0 Special lobe-specific silk protein SSP160 CbtA PF09490.10 EGG15575.1 - 2.6 7.8 5.9 4.4 7.0 5.9 1.4 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Ecl1 PF12855.7 EGG15575.1 - 6.4 7.9 35.2 2.6 9.2 2.3 2.2 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins p450 PF00067.22 EGG15578.1 - 7.1e-88 295.4 0.1 8.8e-88 295.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Wbp11 PF09429.10 EGG15579.1 - 1e-05 25.8 11.3 1e-05 25.8 11.3 2.3 3 1 0 3 3 3 1 WW domain binding protein 11 tRNA-synt_1c PF00749.21 EGG15579.1 - 0.075 11.9 0.2 0.12 11.3 0.2 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain DUF1168 PF06658.12 EGG15579.1 - 7.2 6.4 14.1 0.097 12.5 5.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) T4-Gluco-transf PF09198.10 EGG15580.1 - 0.085 12.5 0.4 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase Abhydrolase_6 PF12697.7 EGG15581.1 - 0.00035 21.2 0.0 0.00047 20.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG15581.1 - 0.00059 19.6 0.1 0.00089 19.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold ArsC PF03960.15 EGG15583.1 - 0.077 13.0 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 ArsC family ORC_WH_C PF18137.1 EGG15583.1 - 0.098 12.7 0.5 0.23 11.5 0.5 1.5 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF3586 PF12131.8 EGG15583.1 - 0.89 9.8 2.8 2.2 8.6 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) Strep_SA_rep PF06696.11 EGG15584.1 - 0.11 12.6 0.3 0.19 11.7 0.3 1.5 1 0 0 1 1 1 0 Streptococcal surface antigen repeat DNase_II PF03265.15 EGG15585.1 - 1.2e-05 24.8 0.2 1.5e-05 24.5 0.2 1.1 1 0 0 1 1 1 1 Deoxyribonuclease II DUF202 PF02656.15 EGG15586.1 - 0.00064 20.1 2.0 0.0012 19.3 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) PALP PF00291.25 EGG15587.1 - 1.1e-48 166.1 0.0 1.5e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Connexin PF00029.19 EGG15588.1 - 0.0032 17.2 0.3 0.0032 17.2 0.3 2.2 2 1 0 2 2 2 1 Connexin FmdE PF02663.14 EGG15588.1 - 0.15 12.1 4.0 5.1 7.1 0.0 2.3 1 1 1 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Abhydrolase_6 PF12697.7 EGG15589.1 - 0.00046 20.9 0.0 0.00055 20.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG15589.1 - 0.00071 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1563 PF07599.11 EGG15589.1 - 0.19 11.9 0.5 2.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1563) Abhydrolase_6 PF12697.7 EGG15592.1 - 0.00026 21.7 0.0 0.00032 21.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG15592.1 - 0.00036 20.3 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1906 PF08924.11 EGG15594.1 - 0.081 13.1 0.0 0.091 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) Ras PF00071.22 EGG15595.1 - 2.8e-11 43.3 0.0 4.3e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGG15595.1 - 0.0079 16.4 0.5 0.13 12.5 0.0 2.6 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNase_H PF00075.24 EGG15598.1 - 0.17 12.0 0.1 0.34 11.1 0.1 1.5 1 0 0 1 1 1 0 RNase H DUF4960 PF16324.5 EGG15599.1 - 0.00016 21.4 0.0 0.58 9.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4960) FoP_duplication PF13865.6 EGG15599.1 - 0.0004 20.9 1.0 0.54 10.8 0.1 2.4 2 0 0 2 2 2 2 C-terminal duplication domain of Friend of PRMT1 RNase_H PF00075.24 EGG15599.1 - 0.00056 20.1 0.3 0.99 9.6 0.0 2.7 2 0 0 2 2 2 2 RNase H DUF1133 PF06576.11 EGG15599.1 - 0.00065 19.1 0.1 0.9 8.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1133) DUF3213 PF11491.8 EGG15599.1 - 0.005 17.0 0.5 5.7 7.2 0.1 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3213) DUF1216 PF06746.11 EGG15599.1 - 0.014 15.4 0.2 5 7.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) HHH PF00633.23 EGG15599.1 - 0.13 12.2 0.2 36 4.5 0.0 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix motif DUF167 PF02594.16 EGG15599.1 - 0.15 12.2 0.0 24 5.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised ACR, YggU family COG1872 YtxH PF12732.7 EGG15599.1 - 3.9 8.1 5.6 11 6.7 0.2 3.9 4 0 0 4 4 4 0 YtxH-like protein DDE_Tnp_1_7 PF13843.6 EGG15600.1 - 9.3e-27 94.2 3.4 9.3e-27 94.2 3.4 3.6 3 1 0 3 3 3 1 Transposase IS4 Apt1 PF10351.9 EGG15600.1 - 0.14 10.9 21.0 0.33 9.8 18.1 2.4 2 1 0 2 2 2 0 Golgi-body localisation protein domain Macoilin PF09726.9 EGG15600.1 - 1.3 7.5 22.7 2.5 6.5 22.7 1.4 1 0 0 1 1 1 0 Macoilin family TFIID-18kDa PF02269.16 EGG15603.1 - 6.6e-30 103.0 1.0 9.3e-30 102.5 1.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF3138 PF11336.8 EGG15603.1 - 0.028 13.1 0.1 0.037 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SOG2 PF10428.9 EGG15603.1 - 0.041 13.1 8.9 0.043 13.0 8.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein CBFD_NFYB_HMF PF00808.23 EGG15603.1 - 0.077 13.3 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Radical_SAM PF04055.21 EGG15604.1 - 9.8e-11 42.3 0.1 2.2e-10 41.2 0.1 1.6 1 1 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 EGG15604.1 - 4.5e-10 39.5 0.2 1.5e-09 37.8 0.1 1.9 2 0 0 2 2 2 1 HemN C-terminal domain EMG1 PF03587.14 EGG15605.1 - 1.4e-91 305.5 0.0 2e-91 305.0 0.0 1.2 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase SIT PF15330.6 EGG15607.1 - 0.00082 19.8 0.0 0.002 18.6 0.0 1.6 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT Chs7 PF12271.8 EGG15607.1 - 0.0018 17.7 0.4 0.0018 17.7 0.4 1.9 3 0 0 3 3 3 1 Chitin synthase export chaperone SurA_N_2 PF13623.6 EGG15607.1 - 0.17 11.7 1.3 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 SurA N-terminal domain DUF4820 PF16091.5 EGG15608.1 - 0.98 8.7 9.7 0.31 10.4 0.7 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4820) RRN3 PF05327.11 EGG15608.1 - 1.8 7.0 8.8 0.088 11.3 3.2 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 HCV_NS2 PF01538.18 EGG15609.1 - 0.069 12.8 3.2 6.2 6.4 0.0 3.0 3 0 0 3 3 3 0 Hepatitis C virus non-structural protein NS2 DUF4834 PF16118.5 EGG15609.1 - 0.07 14.1 3.7 0.085 13.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF4064 PF13273.6 EGG15609.1 - 0.24 11.7 3.3 1.1 9.6 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) E1-E2_ATPase PF00122.20 EGG15609.1 - 0.28 10.7 3.3 2.4 7.6 2.2 2.3 2 0 0 2 2 2 0 E1-E2 ATPase Promethin PF16015.5 EGG15609.1 - 0.43 10.5 7.7 0.056 13.4 1.6 2.3 2 1 0 2 2 2 0 Promethin ETRAMP PF09716.10 EGG15609.1 - 0.59 10.2 4.5 0.95 9.6 1.3 2.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FtsX PF02687.21 EGG15609.1 - 7.2 7.2 8.0 16 6.0 3.5 3.0 3 1 0 3 3 3 0 FtsX-like permease family Claudin_2 PF13903.6 EGG15611.1 - 0.18 11.6 0.3 0.18 11.6 0.3 3.5 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF2085 PF09858.9 EGG15611.1 - 0.2 12.2 4.2 0.65 10.5 1.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) MARVEL PF01284.23 EGG15611.1 - 0.22 11.5 16.4 0.94 9.5 8.2 2.4 1 1 0 2 2 2 0 Membrane-associating domain TcpE PF12648.7 EGG15611.1 - 0.32 11.5 6.8 0.13 12.8 3.0 2.0 2 0 0 2 2 2 0 TcpE family DUF2207 PF09972.9 EGG15611.1 - 1.3 7.7 4.7 0.76 8.5 2.9 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SUR7 PF06687.12 EGG15611.1 - 1.5 8.4 17.7 0.11 12.1 9.1 2.6 2 1 1 3 3 3 0 SUR7/PalI family SAC3 PF12209.8 EGG15612.1 - 0.17 12.1 3.6 0.61 10.3 0.6 2.2 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain WD40 PF00400.32 EGG15613.1 - 9.8e-10 38.9 9.7 0.0028 18.4 0.0 5.7 4 1 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG15613.1 - 2e-09 37.6 0.1 0.056 13.7 0.0 4.9 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGG15613.1 - 0.016 14.2 0.8 1.3 7.9 0.3 2.5 2 1 1 3 3 3 0 Coatomer WD associated region PD40 PF07676.12 EGG15613.1 - 0.073 13.0 0.7 2 8.5 0.2 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ApoB100_C PF12491.8 EGG15614.1 - 0.038 14.0 0.1 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal ApoB100_C PF12491.8 EGG15615.1 - 0.063 13.2 0.0 0.35 10.9 0.0 2.3 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal Cation_efflux PF01545.21 EGG15617.1 - 7.9e-48 162.8 8.0 1.1e-47 162.3 8.0 1.2 1 0 0 1 1 1 1 Cation efflux family DUF2417 PF10329.9 EGG15617.1 - 0.063 12.7 0.0 0.2 11.1 0.0 1.9 1 0 0 1 1 1 0 Region of unknown function (DUF2417) PNISR PF15996.5 EGG15617.1 - 1.5 9.0 7.8 0.24 11.7 3.9 1.7 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR PBP1_TM PF14812.6 EGG15617.1 - 1.6 9.2 17.2 3.2 8.2 4.8 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4834 PF16118.5 EGG15617.1 - 4 8.5 0.0 4 8.5 0.0 3.9 3 2 0 3 3 3 0 Domain of unknown function (DUF4834) p450 PF00067.22 EGG15618.1 - 1.6e-99 333.8 0.0 1.8e-99 333.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CadC_C1 PF18500.1 EGG15618.1 - 0.15 12.2 0.6 0.25 11.5 0.1 1.6 2 0 0 2 2 2 0 CadC C-terminal domain 1 CDC45 PF02724.14 EGG15619.1 - 0.0051 15.2 3.9 0.0043 15.4 3.9 1.2 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 EGG15619.1 - 0.061 13.4 14.8 0.08 13.0 14.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Connexin PF00029.19 EGG15619.1 - 0.31 10.8 3.3 0.38 10.5 3.3 1.2 1 0 0 1 1 1 0 Connexin TLP-20 PF06088.11 EGG15619.1 - 0.81 9.6 9.8 0.043 13.7 4.7 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Amino_oxidase PF01593.24 EGG15620.1 - 5e-37 128.3 0.0 6.8e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGG15620.1 - 1.3e-07 31.7 0.0 3.4e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGG15620.1 - 0.022 14.1 0.1 0.087 12.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGG15620.1 - 0.026 13.8 0.2 0.043 13.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Mucin PF01456.17 EGG15620.1 - 2 8.4 16.7 3.7 7.5 16.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein EGF_2 PF07974.13 EGG15621.1 - 0.055 13.9 38.8 0.11 12.9 9.1 3.0 3 0 0 3 3 3 0 EGF-like domain EB PF01683.18 EGG15621.1 - 0.073 13.4 19.5 0.86 9.9 4.7 2.7 2 0 0 2 2 2 0 EB module DUF5643 PF18705.1 EGG15621.1 - 0.12 12.3 4.3 2.8 7.9 0.8 3.3 2 0 0 2 2 2 0 Family of unknown function (DUF5643) TIG PF01833.24 EGG15621.1 - 0.14 12.2 17.9 0.088 12.9 0.7 4.7 3 0 0 3 3 3 0 IPT/TIG domain LRR_8 PF13855.6 EGG15621.1 - 0.26 11.1 5.9 14 5.5 0.0 4.5 4 1 0 4 4 4 0 Leucine rich repeat DUF719 PF05334.13 EGG15622.1 - 0.012 15.9 0.7 0.012 15.9 0.7 5.6 2 2 2 4 4 4 0 Protein of unknown function (DUF719) Nodulin PF02451.15 EGG15622.1 - 0.087 12.3 0.5 0.38 10.2 0.4 2.0 1 1 1 2 2 2 0 Nodulin Abhydrolase_1 PF00561.20 EGG15623.1 - 3.6e-06 26.8 0.1 9.3e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG15623.1 - 4.4e-05 24.2 0.0 5.8e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG15623.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GCD14 PF08704.10 EGG15623.1 - 0.16 11.6 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit zf-RING_10 PF16685.5 EGG15624.1 - 0.053 13.7 0.1 0.18 11.9 0.1 2.0 1 0 0 1 1 1 0 zinc RING finger of MSL2 Acyl_transf_3 PF01757.22 EGG15625.1 - 2.3e-20 73.0 44.7 2.3e-20 73.0 44.7 1.6 2 0 0 2 2 2 1 Acyltransferase family Syndecan PF01034.20 EGG15625.1 - 0.16 11.9 2.8 1 9.3 0.2 3.0 3 0 0 3 3 3 0 Syndecan domain Insulin_TMD PF17870.1 EGG15625.1 - 1.5 8.9 8.8 25 5.0 0.1 3.6 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment RNF220 PF15926.5 EGG15626.1 - 1.2e-10 41.5 9.6 1.2e-10 41.5 9.6 5.1 2 2 2 4 4 3 2 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 EGG15626.1 - 4.2e-10 39.3 11.4 4.2e-10 39.3 11.4 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG15626.1 - 0.0011 18.8 10.8 0.0011 18.8 10.8 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG15626.1 - 0.005 16.8 7.8 0.005 16.8 7.8 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGG15626.1 - 0.006 16.4 8.5 0.006 16.4 8.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGG15626.1 - 0.011 15.9 7.2 0.011 15.9 7.2 2.6 3 0 0 3 3 3 0 zinc RING finger of MSL2 Ribosomal_L33 PF00471.20 EGG15626.1 - 0.071 13.6 0.1 0.38 11.2 0.1 2.4 1 0 0 1 1 1 0 Ribosomal protein L33 AT_hook PF02178.19 EGG15626.1 - 0.075 12.9 17.4 0.04 13.8 1.6 2.8 2 0 0 2 2 2 0 AT hook motif zf-Nse PF11789.8 EGG15626.1 - 0.71 9.7 5.1 3 7.7 5.1 2.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGG15626.1 - 0.9 9.6 14.1 0.27 11.3 9.6 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGG15626.1 - 0.95 9.6 8.1 0.19 11.8 4.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EGG15626.1 - 1.2 9.5 21.0 0.03 14.6 12.0 2.8 3 0 0 3 3 3 0 Ring finger domain RRM_1 PF00076.22 EGG15627.1 - 2.5e-32 110.5 3.0 8e-15 54.4 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG15627.1 - 4.5e-12 45.6 0.2 0.0038 17.1 0.0 3.2 3 0 0 3 3 3 3 Occluded RNA-recognition motif RRM_5 PF13893.6 EGG15627.1 - 1.1e-08 34.7 0.1 0.015 14.9 0.0 3.1 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 EGG15627.1 - 0.039 13.8 6.0 1.2 9.0 0.1 3.5 3 1 0 3 3 3 0 RNA recognition motif DbpA PF03880.15 EGG15627.1 - 0.063 13.3 0.0 0.58 10.2 0.0 2.5 3 0 0 3 3 3 0 DbpA RNA binding domain p450 PF00067.22 EGG15628.1 - 4.5e-97 325.7 0.7 5.8e-97 325.3 0.7 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ino80_Iec3 PF14612.6 EGG15628.1 - 0.029 15.0 0.6 0.048 14.3 0.0 1.6 2 0 0 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling BRCT_2 PF16589.5 EGG15629.1 - 4.1e-12 46.3 0.1 1.3e-06 28.7 0.0 3.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG15629.1 - 6e-10 39.4 0.1 8e-07 29.3 0.1 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain FHA PF00498.26 EGG15629.1 - 1.1e-08 35.3 0.1 2.5e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 EGG15629.1 - 2.8e-05 23.9 0.2 0.00025 20.9 0.1 2.9 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain Yop-YscD_cpl PF16697.5 EGG15629.1 - 0.0001 22.5 0.0 0.00038 20.7 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PTCB-BRCT PF12738.7 EGG15629.1 - 0.038 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain FNIP PF05725.12 EGG15630.1 - 5.1e-11 42.6 0.6 7.8e-08 32.4 0.2 2.4 1 1 1 2 2 2 2 FNIP Repeat SDA1 PF05285.12 EGG15630.1 - 0.0004 19.9 25.1 0.00046 19.7 25.1 1.1 1 0 0 1 1 1 1 SDA1 BSP_II PF05432.11 EGG15630.1 - 0.0038 17.0 25.4 0.005 16.6 25.4 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) F-box-like_2 PF13013.6 EGG15630.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain CDC45 PF02724.14 EGG15630.1 - 0.019 13.3 26.0 0.025 12.9 26.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 EGG15630.1 - 0.023 13.2 28.2 0.029 12.8 28.2 1.0 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 EGG15630.1 - 0.031 12.4 26.8 0.039 12.1 26.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 EGG15630.1 - 0.034 14.3 28.8 0.047 13.8 28.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 EGG15630.1 - 0.098 10.9 30.0 0.13 10.4 30.0 1.1 1 0 0 1 1 1 0 Nop14-like family Drc1-Sld2 PF11719.8 EGG15630.1 - 0.62 9.5 22.3 0.88 9.0 22.3 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein SURF2 PF05477.11 EGG15630.1 - 0.75 9.4 21.8 0.95 9.1 21.8 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF4604 PF15377.6 EGG15630.1 - 0.89 10.0 18.8 1.3 9.4 18.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) CKAP2_C PF15297.6 EGG15630.1 - 0.91 8.5 18.2 1.3 8.0 18.2 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus RRN3 PF05327.11 EGG15630.1 - 1.3 7.4 16.0 1.8 7.0 16.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_S64 PF08192.11 EGG15630.1 - 2.1 6.7 11.9 2.6 6.4 11.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 EGG15630.1 - 3.2 6.4 14.5 4.2 6.0 14.5 1.1 1 0 0 1 1 1 0 Presenilin DUF3915 PF13054.6 EGG15631.1 - 0.019 14.9 0.1 0.038 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) PEX11 PF05648.14 EGG15631.1 - 0.18 11.3 0.2 0.36 10.3 0.2 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Endotoxin_N PF03945.14 EGG15632.1 - 8.3e-10 38.8 0.8 2e-09 37.5 0.8 1.6 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Ricin_B_lectin PF00652.22 EGG15632.1 - 3e-07 30.7 0.5 0.0057 16.9 0.1 3.2 2 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EGG15632.1 - 0.00063 20.4 0.9 0.51 11.1 0.0 3.6 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 EGG15632.1 - 0.0023 17.6 0.1 1.2 8.7 0.1 2.9 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain Nop14 PF04147.12 EGG15633.1 - 6.5e-05 21.4 8.1 6.5e-05 21.4 8.1 2.0 3 0 0 3 3 3 1 Nop14-like family Mpp10 PF04006.12 EGG15633.1 - 0.018 13.5 14.8 0.032 12.7 14.8 1.3 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 EGG15633.1 - 0.11 10.5 25.1 0.22 9.6 25.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EGG15633.1 - 0.41 10.0 19.0 0.67 9.3 19.0 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EGG15633.1 - 0.66 9.3 13.4 1.1 8.5 13.4 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EGG15633.1 - 3.5 5.8 14.1 5.6 5.1 14.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DDE_Tnp_4 PF13359.6 EGG15634.1 - 5.8e-08 32.6 0.0 9.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 EGG15634.1 - 0.0061 16.3 1.2 0.018 14.7 1.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DUF1388 PF07142.12 EGG15634.1 - 0.039 13.9 7.4 0.19 11.7 7.0 2.1 1 1 0 1 1 1 0 Repeat of unknown function (DUF1388) DUF5327 PF17261.2 EGG15634.1 - 0.053 14.3 7.7 0.42 11.4 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) zf-FCS PF06467.14 EGG15634.1 - 0.16 11.9 2.0 0.61 10.1 2.0 2.0 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif RGS12_us1 PF16613.5 EGG15635.1 - 0.048 14.0 0.1 0.057 13.7 0.1 1.1 1 0 0 1 1 1 0 Unstructured region of RGS12 DNase_II PF03265.15 EGG15636.1 - 2.2e-08 33.7 3.2 4.4e-08 32.8 3.2 1.5 1 0 0 1 1 1 1 Deoxyribonuclease II Nop14 PF04147.12 EGG15638.1 - 0.0019 16.5 11.0 0.0057 14.9 10.8 1.8 2 0 0 2 2 2 1 Nop14-like family DNA_pol_phi PF04931.13 EGG15638.1 - 0.17 10.0 20.7 0.34 9.0 20.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EGG15638.1 - 0.38 10.1 16.1 0.61 9.5 16.1 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EGG15638.1 - 0.88 8.8 10.5 1.4 8.2 10.5 1.2 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 EGG15638.1 - 3 6.3 15.9 3.5 6.1 14.0 1.9 1 1 1 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.12 EGG15638.1 - 7.9 5.8 16.3 13 5.1 16.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1574 PF07611.11 EGG15639.1 - 0.13 11.6 0.6 5.8 6.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1574) MACPF PF01823.19 EGG15641.1 - 6.9e-17 62.2 1.2 6.9e-17 62.2 1.2 2.3 1 1 1 2 2 2 1 MAC/Perforin domain MACPF PF01823.19 EGG15642.1 - 4.3e-25 89.0 0.6 1.5e-24 87.3 0.6 1.9 1 0 0 1 1 1 1 MAC/Perforin domain Acyl-thio_N PF12590.8 EGG15644.1 - 0.056 14.0 0.0 0.077 13.6 0.0 1.2 1 0 0 1 1 1 0 Acyl-ATP thioesterase rve PF00665.26 EGG15646.1 - 0.014 15.6 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain DUF5484 PF17583.2 EGG15646.1 - 0.1 12.3 0.4 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5484) Pox_D5 PF03288.16 EGG15649.1 - 0.073 13.6 0.8 0.092 13.3 0.8 1.3 1 1 0 1 1 1 0 Poxvirus D5 protein-like DNase_II PF03265.15 EGG15650.1 - 4.8e-08 32.7 2.8 4.8e-08 32.7 2.8 1.6 1 1 0 1 1 1 1 Deoxyribonuclease II Tobravirus_2B PF05271.11 EGG15650.1 - 0.05 13.5 0.0 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 Tobravirus 2B protein Treacle PF03546.14 EGG15650.1 - 1.2 7.9 12.0 0.053 12.4 3.0 2.2 2 0 0 2 2 2 0 Treacher Collins syndrome protein Treacle DNA_pol_phi PF04931.13 EGG15652.1 - 0.029 12.5 15.9 0.068 11.3 15.9 1.5 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 EGG15652.1 - 0.24 10.7 4.4 0.44 9.8 4.4 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EGG15652.1 - 0.46 8.6 11.4 0.029 12.6 6.3 1.5 2 0 0 2 2 2 0 Nop14-like family CobT PF06213.12 EGG15652.1 - 2.7 7.3 10.0 4.4 6.6 10.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 EGG15652.1 - 7.2 5.9 13.3 13 5.1 13.3 1.3 1 0 0 1 1 1 0 SDA1 BTB PF00651.31 EGG15653.1 - 1.3e-20 73.7 0.0 3e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3361 PF11841.8 EGG15653.1 - 0.0022 18.0 1.0 0.13 12.2 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) V-ATPase_H_N PF03224.14 EGG15653.1 - 0.0038 16.6 0.4 0.01 15.1 0.4 1.7 1 1 0 1 1 1 1 V-ATPase subunit H HEAT PF02985.22 EGG15653.1 - 0.096 13.0 0.0 3.7 8.1 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat Arm PF00514.23 EGG15653.1 - 0.49 10.5 2.1 65 3.8 0.2 4.3 5 1 0 5 5 5 0 Armadillo/beta-catenin-like repeat SPC12 PF06645.13 EGG15654.1 - 1.9e-30 104.7 2.2 2.2e-30 104.5 2.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3021 PF11457.8 EGG15654.1 - 0.0029 17.9 0.4 0.003 17.9 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3021) Tetraspanin PF00335.20 EGG15654.1 - 0.021 14.5 0.1 0.024 14.4 0.1 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF1449 PF07290.11 EGG15654.1 - 0.025 14.2 0.3 0.028 14.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) UPF0093 PF03653.13 EGG15654.1 - 0.043 14.0 0.1 0.051 13.8 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) SLATT_6 PF18169.1 EGG15654.1 - 0.056 13.0 0.9 0.48 10.0 0.1 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 ArsP_1 PF03773.13 EGG15654.1 - 0.16 11.1 3.4 0.39 9.8 3.6 1.5 1 1 1 2 2 2 0 Predicted permease RIBIOP_C PF04950.12 EGG15656.1 - 7.8e-104 347.2 1.5 1.3e-103 346.4 0.0 2.1 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGG15656.1 - 3.4e-17 62.3 0.3 2e-16 59.8 0.3 2.4 1 1 0 1 1 1 1 AARP2CN (NUC121) domain RRM_occluded PF16842.5 EGG15656.1 - 0.075 12.9 0.3 0.42 10.5 0.2 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Glyco_hydro_38N PF01074.22 EGG15657.1 - 2.6e-60 204.2 0.2 4.4e-60 203.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 EGG15657.1 - 1.8e-16 60.0 0.3 3.4e-16 59.2 0.3 1.4 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 EGG15657.1 - 4.3e-15 56.4 0.0 8.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Methyltransf_11 PF08241.12 EGG15658.1 - 1.2e-13 51.6 0.0 1.8e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG15658.1 - 1.7e-10 41.4 0.0 3.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG15658.1 - 1.3e-08 34.8 0.1 1.8e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG15658.1 - 3.1e-07 30.0 0.1 4.3e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGG15658.1 - 2.3e-06 28.3 0.0 3.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EGG15658.1 - 0.0017 17.0 0.0 0.0018 16.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 EGG15658.1 - 0.009 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGG15658.1 - 0.017 15.0 0.0 0.82 9.5 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase MetW PF07021.12 EGG15658.1 - 0.051 13.2 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Spt20 PF12090.8 EGG15659.1 - 0.0015 18.2 26.1 0.0015 18.2 26.1 4.4 3 2 0 3 3 3 1 Spt20 family MRC1 PF09444.10 EGG15660.1 - 7.4 7.1 10.8 0.71 10.4 2.2 2.3 2 0 0 2 2 2 0 MRC1-like domain RWP-RK PF02042.15 EGG15661.1 - 1.9e-24 85.4 0.1 3.6e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_17 PF12728.7 EGG15661.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Utp14 PF04615.13 EGG15661.1 - 3.7 6.0 20.1 4.7 5.6 20.1 1.1 1 0 0 1 1 1 0 Utp14 protein BING4CT PF08149.11 EGG15662.1 - 1.8e-31 107.8 0.0 1.8e-31 107.8 0.0 3.1 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.32 EGG15662.1 - 0.0031 18.3 0.2 0.069 14.1 0.0 3.2 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_2 PF13360.6 EGG15662.1 - 0.076 12.6 0.0 0.77 9.3 0.0 2.3 1 1 1 2 2 2 0 PQQ-like domain Nop25 PF09805.9 EGG15663.1 - 2.8e-14 53.7 21.2 2.8e-14 53.7 21.2 2.5 1 1 1 2 2 2 1 Nucleolar protein 12 (25kDa) BUD22 PF09073.10 EGG15663.1 - 0.079 12.3 32.3 0.11 11.8 32.3 1.2 1 0 0 1 1 1 0 BUD22 Ubie_methyltran PF01209.18 EGG15664.1 - 7.4e-21 74.6 0.2 3.7e-20 72.3 0.2 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGG15664.1 - 7.7e-18 65.0 0.0 1.2e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG15664.1 - 6.2e-17 62.0 0.0 9.8e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG15664.1 - 2.2e-13 50.2 0.0 3.2e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG15664.1 - 3.5e-08 34.1 0.0 5.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG15664.1 - 2.5e-07 30.7 0.0 5.5e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGG15664.1 - 1.8e-05 24.6 0.0 3.2e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EGG15664.1 - 0.0016 18.3 0.1 0.0025 17.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EGG15664.1 - 0.0025 17.6 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EGG15664.1 - 0.003 17.1 0.1 0.0059 16.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain GCD14 PF08704.10 EGG15664.1 - 0.0043 16.8 0.0 0.006 16.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DREV PF05219.12 EGG15664.1 - 0.0088 15.2 0.0 0.018 14.1 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 EGG15664.1 - 0.0089 15.3 0.0 0.018 14.4 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 EGG15664.1 - 0.016 15.1 0.0 0.15 11.9 0.0 2.0 1 1 1 2 2 2 0 Hypothetical methyltransferase MetW PF07021.12 EGG15664.1 - 0.037 13.6 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_20 PF12147.8 EGG15664.1 - 0.044 12.9 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF5484 PF17583.2 EGG15664.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5484) Cons_hypoth95 PF03602.15 EGG15664.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 SUIM_assoc PF16619.5 EGG15665.1 - 2.6e-05 24.2 17.3 0.0089 16.1 1.3 2.7 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 PRIMA1 PF16101.5 EGG15665.1 - 0.036 14.1 1.0 0.094 12.8 1.0 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 AAA_lid_1 PF17857.1 EGG15665.1 - 0.26 11.5 2.0 30 4.9 0.0 3.7 3 0 0 3 3 3 0 AAA+ lid domain Pex26 PF07163.12 EGG15665.1 - 0.66 9.2 3.9 0.49 9.7 0.2 2.1 2 0 0 2 2 2 0 Pex26 protein Med15 PF09606.10 EGG15665.1 - 5.5 5.5 16.5 2.2 6.9 5.9 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal dsDNA_bind PF01984.20 EGG15665.1 - 5.7 7.3 15.0 7.4 6.9 7.5 3.2 3 0 0 3 3 3 0 Double-stranded DNA-binding domain ANAPC_CDC26 PF10471.9 EGG15665.1 - 6.6 7.6 25.5 0.38 11.6 7.1 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 DUF4834 PF16118.5 EGG15665.1 - 9.7 7.2 13.2 3 8.9 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Phostensin_N PF13916.6 EGG15665.1 - 9.8 6.6 9.4 4.1 7.8 1.8 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal RsbRD_N PF14361.6 EGG15666.1 - 0.024 15.3 0.7 6.7 7.5 0.0 3.0 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain UBN_AB PF14075.6 EGG15666.1 - 0.029 14.1 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DUF2096 PF09869.9 EGG15666.1 - 0.1 12.6 2.5 0.28 11.3 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) Clat_adaptor_s PF01217.20 EGG15666.1 - 9.2 6.2 11.7 0.32 10.9 3.8 2.5 2 0 0 2 2 2 0 Clathrin adaptor complex small chain Ank_2 PF12796.7 EGG15667.1 - 0.0008 20.0 5.1 0.046 14.3 0.0 5.4 7 1 0 7 7 7 1 Ankyrin repeats (3 copies) Tubulin_C PF03953.17 EGG15667.1 - 0.11 12.6 1.4 0.35 11.0 1.4 1.8 1 0 0 1 1 1 0 Tubulin C-terminal domain Ank_4 PF13637.6 EGG15667.1 - 0.25 12.0 1.7 7.8 7.2 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeats (many copies) zf-RING_5 PF14634.6 EGG15668.1 - 0.005 16.8 1.8 0.005 16.8 1.8 3.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG15668.1 - 0.057 13.5 0.7 0.057 13.5 0.7 2.5 2 0 0 2 2 2 0 RING-type zinc-finger PH PF00169.29 EGG15669.1 - 8.2e-30 103.4 0.3 2.1e-14 53.9 0.1 2.9 3 0 0 3 3 2 2 PH domain TPR_19 PF14559.6 EGG15669.1 - 6.1e-13 49.1 0.1 0.00026 21.4 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat C2 PF00168.30 EGG15669.1 - 5.2e-12 46.0 0.1 2.8e-09 37.2 0.0 3.1 3 0 0 3 3 3 1 C2 domain TPR_2 PF07719.17 EGG15669.1 - 4.6e-08 32.6 2.4 2.4 8.5 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat PH_3 PF14593.6 EGG15669.1 - 4.7e-08 33.1 1.9 4.6e-07 29.9 0.2 3.0 2 1 0 2 2 2 1 PH domain TPR_11 PF13414.6 EGG15669.1 - 1.3e-07 31.2 0.0 0.0031 17.2 0.1 3.1 3 0 0 3 3 3 2 TPR repeat PH_6 PF15406.6 EGG15669.1 - 2.4e-06 27.8 0.1 0.00029 21.1 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain TPR_8 PF13181.6 EGG15669.1 - 4.3e-06 26.5 2.1 2.3 8.7 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG15669.1 - 1.1e-05 25.0 7.3 0.16 11.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat PH_8 PF15409.6 EGG15669.1 - 3.8e-05 23.9 0.1 0.015 15.5 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 EGG15669.1 - 0.00023 21.5 0.7 0.062 13.7 0.0 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain TPR_14 PF13428.6 EGG15669.1 - 0.00036 21.1 0.0 3.9 8.5 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG15669.1 - 0.0017 18.6 0.5 32 4.9 0.1 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG15669.1 - 0.0031 17.7 0.8 13 6.1 0.0 3.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGG15669.1 - 0.005 17.5 0.0 3.1 8.5 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat PH_13 PF16652.5 EGG15669.1 - 0.0097 15.7 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EGG15669.1 - 0.017 15.5 9.5 4.6 7.7 0.0 4.9 4 1 0 4 4 3 0 Pleckstrin homology domain TPR_17 PF13431.6 EGG15669.1 - 0.15 12.5 1.9 5.7 7.6 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat HCMV_UL139 PF12507.8 EGG15669.1 - 1.3 9.4 4.3 6.1 7.2 0.5 2.8 3 0 0 3 3 3 0 Human Cytomegalovirus UL139 protein Peptidase_S10 PF00450.22 EGG15670.1 - 2.9e-98 330.0 3.1 4.9e-98 329.3 3.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase TPPK_C PF12555.8 EGG15670.1 - 0.091 12.8 0.1 0.33 11.0 0.1 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal MACPF PF01823.19 EGG15672.1 - 3.3e-17 63.3 1.4 7.1e-17 62.2 1.4 1.5 1 0 0 1 1 1 1 MAC/Perforin domain PA14 PF07691.12 EGG15672.1 - 8.4e-08 32.1 0.0 2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 PA14 domain MACPF PF01823.19 EGG15673.1 - 5.5e-23 82.2 2.2 5.5e-23 82.2 2.2 2.3 1 1 1 2 2 2 1 MAC/Perforin domain MACPF PF01823.19 EGG15674.1 - 1.7e-17 64.3 1.2 3.3e-17 63.3 1.2 1.5 1 0 0 1 1 1 1 MAC/Perforin domain PA14 PF07691.12 EGG15674.1 - 9.8e-08 31.9 0.0 2.5e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 PA14 domain MACPF PF01823.19 EGG15676.1 - 5.7e-23 82.1 2.4 5.7e-23 82.1 2.4 2.3 1 1 1 2 2 2 1 MAC/Perforin domain DNase_II PF03265.15 EGG15677.1 - 1.3e-11 44.4 0.2 2.1e-05 24.0 0.0 2.6 2 1 0 2 2 2 2 Deoxyribonuclease II Peptidase_S10 PF00450.22 EGG15678.1 - 2.7e-05 23.8 0.0 3.1e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Cyt-b5 PF00173.28 EGG15683.1 - 2.5e-19 69.2 0.0 4.3e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NIF PF03031.18 EGG15684.1 - 4.9e-21 75.1 0.1 1e-20 74.1 0.1 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Spt20 PF12090.8 EGG15684.1 - 0.0045 16.6 7.3 0.0045 16.6 7.3 2.1 2 0 0 2 2 2 1 Spt20 family Connexin PF00029.19 EGG15684.1 - 0.019 14.7 2.2 0.019 14.7 2.2 1.8 2 0 0 2 2 2 0 Connexin HCO3_cotransp PF00955.21 EGG15684.1 - 0.12 11.2 4.6 0.2 10.4 4.6 1.3 1 0 0 1 1 1 0 HCO3- transporter family DUF5427 PF10310.9 EGG15684.1 - 0.13 11.2 11.7 0.024 13.6 5.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5427) CSG2 PF16965.5 EGG15684.1 - 0.21 10.5 4.6 0.4 9.6 4.6 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator EOS1 PF12326.8 EGG15684.1 - 0.24 11.3 4.0 0.28 11.1 2.5 1.7 2 0 0 2 2 2 0 N-glycosylation protein Serinc PF03348.15 EGG15684.1 - 0.24 10.3 4.9 0.38 9.6 4.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF908 PF06012.12 EGG15684.1 - 0.35 10.2 8.1 0.61 9.4 8.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) OATP PF03137.20 EGG15684.1 - 1.2 7.4 2.9 1.8 6.7 2.9 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CPSF100_C PF13299.6 EGG15684.1 - 1.3 9.2 10.4 0.77 9.9 7.4 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Kei1 PF08552.11 EGG15684.1 - 1.7 8.5 3.6 1.1 9.1 1.9 1.5 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Menin PF05053.13 EGG15684.1 - 1.8 6.9 7.0 3.6 5.8 7.0 1.5 1 0 0 1 1 1 0 Menin ALMT PF11744.8 EGG15684.1 - 3.2 6.5 10.6 0.062 12.1 4.1 1.4 2 0 0 2 2 2 0 Aluminium activated malate transporter NPR3 PF03666.13 EGG15684.1 - 4.5 5.9 15.3 0.12 11.1 8.9 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SHR3_chaperone PF08229.11 EGG15684.1 - 4.8 6.1 6.0 8.6 5.3 0.0 2.6 2 0 0 2 2 2 0 ER membrane protein SH3 RNA_pol_Rpc4 PF05132.14 EGG15684.1 - 5.2 7.5 10.4 0.67 10.4 5.2 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 LRAT PF04970.13 EGG15686.1 - 2.8e-05 24.4 0.1 6.1e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 Lecithin retinol acyltransferase Peptidase_C97 PF05903.14 EGG15686.1 - 0.15 11.8 1.9 0.23 11.3 1.9 1.5 1 1 0 1 1 1 0 PPPDE putative peptidase domain 2OG-FeII_Oxy PF03171.20 EGG15687.1 - 1.1e-16 61.2 0.3 4.6e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily VASt PF16016.5 EGG15688.1 - 5.1e-18 65.9 0.8 1.1e-17 64.9 0.8 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain XhlA PF10779.9 EGG15688.1 - 0.015 15.5 1.6 0.015 15.5 1.6 2.2 2 0 0 2 2 2 0 Haemolysin XhlA EMP24_GP25L PF01105.24 EGG15688.1 - 0.031 14.2 0.5 0.031 14.2 0.5 2.3 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF4337 PF14235.6 EGG15688.1 - 0.083 13.0 0.7 0.17 12.0 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CLZ PF16526.5 EGG15688.1 - 0.11 12.9 5.2 0.057 13.8 1.9 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4011 PF13195.6 EGG15688.1 - 0.33 10.8 5.1 0.68 9.8 4.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) Peroxin-13_N PF04088.13 EGG15688.1 - 2.1 8.6 6.3 5 7.4 2.7 2.8 2 1 0 2 2 2 0 Peroxin 13, N-terminal region DUF5412 PF17428.2 EGG15689.1 - 0.0047 16.8 0.1 0.0063 16.4 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5412) DUF3430 PF11912.8 EGG15689.1 - 0.026 14.6 14.7 0.032 14.3 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Abhydrolase_6 PF12697.7 EGG15692.1 - 3.8e-06 27.7 0.0 6.2e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG15692.1 - 8.6e-05 22.3 0.1 0.00015 21.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG15692.1 - 0.19 10.9 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 WI12 PF07107.11 EGG15696.1 - 0.054 13.6 0.0 0.062 13.4 0.0 1.1 1 0 0 1 1 1 0 Wound-induced protein WI12 RTC PF01137.21 EGG15697.1 - 0.15 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase Phi-29_GP16_7 PF06720.11 EGG15698.1 - 0.014 15.2 0.4 0.53 10.1 0.2 2.9 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 Ribosomal_60s PF00428.19 EGG15698.1 - 0.3 11.7 0.0 0.3 11.7 0.0 4.0 4 0 0 4 4 4 0 60s Acidic ribosomal protein RIH_assoc PF08454.11 EGG15698.1 - 5.6 6.9 10.0 1.4 8.8 3.9 3.3 3 1 0 3 3 3 0 RyR and IP3R Homology associated DNase_II PF03265.15 EGG15700.1 - 6.6e-05 22.4 1.2 0.00059 19.2 0.0 2.5 3 0 0 3 3 3 1 Deoxyribonuclease II Cupin_8 PF13621.6 EGG15701.1 - 1.7e-18 67.3 0.6 1.7e-18 67.3 0.6 2.9 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 EGG15701.1 - 2.7e-11 43.9 4.6 1.5e-07 31.8 0.1 3.5 3 0 0 3 3 3 2 JmjC domain, hydroxylase Cupin_4 PF08007.12 EGG15701.1 - 5.4e-06 26.1 0.1 1.8e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 EGG15701.1 - 0.027 14.2 0.0 0.079 12.7 0.0 1.8 1 0 0 1 1 1 0 Cupin domain FtsJ PF01728.19 EGG15702.1 - 3e-66 222.9 0.0 3.6e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EGG15702.1 - 0.076 13.7 0.0 0.21 12.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EGG15702.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Avl9 PF09794.9 EGG15703.1 - 1.1e-10 40.7 0.1 5.4e-10 38.5 0.1 2.0 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 EGG15703.1 - 1.1e-09 38.2 0.2 4.8e-09 36.2 0.2 2.0 1 1 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 EGG15703.1 - 4.9e-05 23.3 0.3 0.00035 20.6 0.2 2.3 2 0 0 2 2 2 1 DENN (AEX-3) domain Complex1_LYR PF05347.15 EGG15705.1 - 2.8e-10 40.1 1.7 2e-09 37.3 1.7 2.0 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGG15705.1 - 0.0024 18.6 0.0 0.003 18.3 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like MoCF_biosynth PF00994.24 EGG15708.1 - 1.2e-55 187.1 0.8 1e-26 93.3 0.1 2.6 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EGG15708.1 - 1.1e-38 132.5 0.1 2e-38 131.7 0.1 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EGG15708.1 - 1.4e-15 57.3 0.0 2.7e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Dak1 PF02733.17 EGG15709.1 - 3e-106 354.9 0.6 5.9e-106 353.9 0.6 1.5 1 1 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EGG15709.1 - 4.8e-43 147.1 0.3 7.4e-42 143.2 0.0 2.8 3 1 1 4 4 4 1 DAK2 domain m_DGTX_Dc1a_b_c PF17491.2 EGG15710.1 - 0.13 12.9 0.6 0.32 11.7 0.6 1.6 1 0 0 1 1 1 0 Spider Toxins mu-diguetoxin-1 a, b and c Acyl-CoA_dh_M PF02770.19 EGG15712.1 - 3.3e-13 49.7 0.0 5.9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGG15712.1 - 6.7e-09 36.1 0.0 1e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGG15712.1 - 0.02 15.6 0.0 0.11 13.1 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_ox_N PF14749.6 EGG15712.1 - 0.092 13.3 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal TIG PF01833.24 EGG15713.1 - 2.2e-11 43.7 13.6 1e-05 25.5 1.4 4.1 3 0 0 3 3 3 3 IPT/TIG domain AA_permease PF00324.21 EGG15713.1 - 3.1e-09 35.9 0.1 5e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Amino acid permease EGF_2 PF07974.13 EGG15713.1 - 0.054 13.9 7.7 0.11 12.9 7.7 1.5 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGG15713.1 - 6.8 7.5 7.4 17 6.2 7.4 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF Myb_DNA-binding PF00249.31 EGG15716.1 - 8.1e-10 38.7 0.1 0.0026 17.9 0.1 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG15716.1 - 2.3e-09 37.4 1.5 0.0086 16.3 0.1 4.7 4 1 1 5 5 5 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGG15716.1 - 0.35 11.1 5.7 1.2 9.4 0.0 3.0 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 TFIIA PF03153.13 EGG15716.1 - 1.2 9.0 10.8 2.1 8.3 10.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med20 PF08612.11 EGG15718.1 - 0.059 12.7 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Sec16_C PF12931.7 EGG15721.1 - 1.2e-48 166.3 0.1 1.2e-48 166.3 0.1 2.7 3 0 0 3 3 3 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EGG15721.1 - 2.4e-16 60.4 5.4 6.7e-16 58.9 0.0 3.7 3 0 0 3 3 3 1 Vesicle coat trafficking protein Sec16 mid-region AD PF09793.9 EGG15722.1 - 2.5e-27 94.8 0.1 3.6e-27 94.3 0.1 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 EGG15722.1 - 0.0022 17.6 0.0 0.009 15.6 0.0 1.9 2 0 0 2 2 2 1 Gemin6 protein Peptidase_M11 PF05548.11 EGG15722.1 - 0.023 13.9 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Gametolysin peptidase M11 DUF2259 PF10016.9 EGG15722.1 - 0.048 13.6 0.0 0.061 13.3 0.0 1.1 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) ACBP PF00887.19 EGG15723.1 - 1e-27 96.2 3.1 1.1e-27 96.0 3.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 EGG15723.1 - 0.0013 19.1 0.2 0.0022 18.4 0.2 1.6 1 1 0 1 1 1 1 FERM central domain Peptidase_C1 PF00112.23 EGG15724.1 - 1.5e-43 149.5 1.7 2.2e-43 148.9 1.7 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Ribosomal_S7 PF00177.21 EGG15725.1 - 2.2e-33 115.0 0.4 2.7e-33 114.7 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF3430 PF11912.8 EGG15728.1 - 2.1e-14 54.1 18.1 2.4e-14 53.9 18.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF4215 PF13948.6 EGG15728.1 - 0.017 15.6 3.5 0.017 15.6 3.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4215) Insulin_TMD PF17870.1 EGG15728.1 - 0.034 14.2 0.4 0.067 13.3 0.4 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment MiAMP1 PF09117.10 EGG15728.1 - 0.089 13.0 6.6 0.82 10.0 0.5 3.4 2 1 1 3 3 3 0 MiAMP1 Peptidase_C1 PF00112.23 EGG15729.1 - 3.2e-52 177.8 0.7 3.9e-52 177.5 0.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGG15729.1 - 0.024 13.4 0.9 0.044 12.5 0.1 1.7 2 0 0 2 2 2 0 Peptidase C1-like family DUF866 PF05907.13 EGG15730.1 - 2e-40 138.3 2.2 4.6e-40 137.1 2.2 1.6 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Apt1 PF10351.9 EGG15730.1 - 0.15 10.9 6.7 0.19 10.5 6.7 1.3 1 1 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EGG15730.1 - 1.7 7.1 7.8 2 6.9 7.8 1.2 1 0 0 1 1 1 0 Macoilin family 2OG-FeII_Oxy_3 PF13640.6 EGG15731.1 - 0.00011 23.0 0.0 0.00017 22.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RhoGAP PF00620.27 EGG15732.1 - 8.2e-39 132.9 0.6 1.6e-38 131.9 0.6 1.5 1 0 0 1 1 1 1 RhoGAP domain Profilin PF00235.19 EGG15733.1 - 7.7e-12 45.6 0.0 9.4e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Profilin RasGAP PF00616.19 EGG15734.1 - 1.9e-59 200.9 0.1 9.4e-59 198.6 0.1 2.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase ABC_membrane PF00664.23 EGG15734.1 - 3.5e-58 197.4 25.3 9.6e-58 196.0 25.3 1.8 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGG15734.1 - 4.6e-33 114.6 0.0 2.2e-32 112.4 0.0 2.3 1 0 0 1 1 1 1 ABC transporter RasGAP_C PF03836.15 EGG15734.1 - 2.5e-32 111.9 4.9 6e-32 110.7 4.9 1.7 1 0 0 1 1 1 1 RasGAP C-terminus SMC_N PF02463.19 EGG15734.1 - 0.0004 19.9 0.0 0.025 14.0 0.1 2.4 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGG15734.1 - 0.015 15.0 0.2 0.04 13.7 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Csm1_B PF18211.1 EGG15734.1 - 0.028 14.2 0.1 0.2 11.5 0.1 2.5 1 0 0 1 1 1 0 Csm1 subunit domain B Zeta_toxin PF06414.12 EGG15734.1 - 0.061 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MTP18 PF10558.9 EGG15734.1 - 0.29 11.1 2.3 9.4 6.2 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) PH_3 PF14593.6 EGG15738.1 - 0.023 14.8 0.9 0.036 14.2 0.9 1.3 1 0 0 1 1 1 0 PH domain PARP PF00644.20 EGG15741.1 - 1.8e-16 60.3 0.7 2.7e-13 49.9 0.1 2.9 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain zf-primase PF09329.11 EGG15741.1 - 0.0067 16.2 3.6 0.021 14.6 1.3 2.4 2 0 0 2 2 2 1 Primase zinc finger PBP1_TM PF14812.6 EGG15741.1 - 0.49 10.8 21.7 3.4 8.1 8.7 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 EGG15741.1 - 0.68 10.2 17.1 2.1 8.6 4.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 EGG15741.1 - 4.2 7.0 11.9 1.9 8.2 1.4 2.4 2 0 0 2 2 2 0 FAM176 family AdoHcyase PF05221.17 EGG15743.1 - 4.4e-133 443.0 0.0 3.2e-73 246.5 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EGG15743.1 - 2e-85 284.8 2.9 3.3e-85 284.1 2.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGG15743.1 - 9.3e-09 34.9 0.1 1.8e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EGG15743.1 - 0.00045 19.8 0.1 0.00072 19.2 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EGG15743.1 - 0.0055 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 EGG15743.1 - 0.051 14.2 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 EGG15743.1 - 0.052 12.9 0.4 0.22 10.8 0.4 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Snf7 PF03357.21 EGG15745.1 - 6.9e-15 55.1 14.6 6.9e-15 55.1 14.6 1.5 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 EGG15745.1 - 6.9e-06 26.1 6.0 1e-05 25.5 6.0 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway SAS4 PF15460.6 EGG15745.1 - 0.084 13.0 0.3 0.084 13.0 0.3 2.6 2 1 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 DUF3535 PF12054.8 EGG15746.1 - 2.7e-71 241.1 23.2 1.3e-70 238.8 4.4 4.7 5 0 0 5 5 5 3 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EGG15746.1 - 2.4e-61 207.4 0.0 8e-61 205.7 0.0 1.9 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG15746.1 - 2.4e-18 66.5 2.3 1.6e-17 63.8 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HEAT PF02985.22 EGG15746.1 - 1.4e-14 52.9 3.3 1.1 9.7 0.0 9.4 8 1 1 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 EGG15746.1 - 2.5e-11 43.8 6.2 0.00021 21.7 0.0 6.7 8 0 0 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.6 EGG15746.1 - 8.8e-07 29.2 7.0 0.00057 20.2 0.2 5.0 5 1 1 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.7 EGG15746.1 - 9.5e-05 22.9 0.0 2.5 8.8 0.0 4.3 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region ubiquitin PF00240.23 EGG15747.1 - 0.019 14.7 0.1 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin family Ge1_WD40 PF16529.5 EGG15748.1 - 6.3e-15 54.9 0.0 3.3e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGG15748.1 - 1.1e-05 25.0 3.0 0.0009 18.7 0.3 2.5 2 0 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 EGG15748.1 - 0.00069 19.9 0.0 0.05 13.9 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Condensin2nSMC PF12422.8 EGG15748.1 - 0.0086 16.3 4.5 0.31 11.2 1.7 2.5 2 0 0 2 2 2 2 Condensin II non structural maintenance of chromosomes subunit Hira PF07569.11 EGG15748.1 - 0.08 12.7 0.0 0.08 12.7 0.0 3.3 4 1 0 4 4 4 0 TUP1-like enhancer of split EppA_BapA PF07268.11 EGG15748.1 - 0.22 11.5 1.9 6.7 6.6 0.1 2.5 2 0 0 2 2 2 0 Exported protein precursor (EppA/BapA) Tcp10_C PF07202.13 EGG15748.1 - 6.5 6.7 9.9 2.4 8.1 1.2 2.6 2 0 0 2 2 2 0 T-complex protein 10 C-terminus WD40 PF00400.32 EGG15750.1 - 1.4e-07 32.1 3.9 0.013 16.4 0.0 4.7 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG15750.1 - 7.9e-05 22.9 0.0 0.8 10.0 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG15751.1 - 6.1e-05 23.7 0.9 0.047 14.6 0.9 2.2 1 1 0 1 1 1 1 WD domain, G-beta repeat PD40 PF07676.12 EGG15751.1 - 0.00034 20.5 0.9 0.37 10.8 0.1 2.3 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 EGG15751.1 - 0.041 14.2 0.0 0.23 11.8 0.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Ses_B PF17046.5 EGG15751.1 - 0.085 12.8 2.1 5.6 7.0 0.5 2.3 2 0 0 2 2 2 0 SesB domain on fungal death-pathway protein MmgE_PrpD PF03972.14 EGG15752.1 - 2e-141 471.5 0.0 2.5e-141 471.2 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family THF_DHG_CYH_C PF02882.19 EGG15752.1 - 9.7e-69 229.8 2.2 1.8e-68 228.9 2.2 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EGG15752.1 - 1.1e-36 125.7 1.3 2.1e-36 124.7 1.3 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 EGG15752.1 - 0.033 13.1 0.2 0.061 12.3 0.2 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family KORA PF16509.5 EGG15752.1 - 0.049 13.9 0.0 0.17 12.2 0.1 1.8 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor GCV_H PF01597.19 EGG15752.1 - 0.12 12.3 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein CAP_N PF01213.19 EGG15753.1 - 1.2e-99 333.8 4.6 1.2e-99 333.8 4.6 1.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EGG15753.1 - 1.3e-62 210.1 8.9 1.8e-62 209.6 8.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EGG15753.1 - 0.00017 21.3 7.5 0.00081 19.1 7.5 2.0 1 1 0 1 1 1 1 Tubulin binding cofactor C DASH_Dam1 PF08653.10 EGG15753.1 - 0.35 10.7 1.3 5.5 6.9 0.0 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 Xpo1 PF08389.12 EGG15755.1 - 2.2e-35 121.9 12.7 7.8e-35 120.1 1.3 5.2 4 1 1 5 5 5 1 Exportin 1-like protein Rap1a PF18602.1 EGG15755.1 - 0.022 15.1 0.0 2 8.8 0.0 3.1 2 0 0 2 2 2 0 Rap1a immunity proteins Vps35 PF03635.17 EGG15756.1 - 5.6e-255 848.4 26.2 1.1e-254 847.4 26.2 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 G-alpha PF00503.20 EGG15756.1 - 6.3e-97 324.9 7.1 6.3e-97 324.9 7.1 2.6 2 1 0 2 2 2 1 G-protein alpha subunit TRAP-gamma PF07074.12 EGG15756.1 - 1.3e-18 67.1 7.2 1.3e-18 67.1 7.2 2.1 2 0 0 2 2 2 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Arf PF00025.21 EGG15756.1 - 2e-12 46.9 0.5 1.6e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG15756.1 - 0.13 12.4 0.0 19 5.4 0.0 3.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF5320 PF17253.2 EGG15756.1 - 0.39 11.8 0.6 1.5 10.0 0.6 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Cation_efflux PF01545.21 EGG15757.1 - 6.2e-46 156.7 9.0 1.1e-45 155.9 9.0 1.4 1 0 0 1 1 1 1 Cation efflux family Hid1 PF12722.7 EGG15757.1 - 2.1 6.4 9.0 3.3 5.7 9.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pyr_redox_2 PF07992.14 EGG15758.1 - 1.2e-33 116.6 0.1 1.6e-33 116.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG15758.1 - 8.8e-18 64.7 0.5 1.1e-10 42.0 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGG15758.1 - 2e-08 34.2 0.1 0.014 15.0 0.0 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGG15758.1 - 5.6e-07 29.1 0.1 0.00058 19.2 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG15758.1 - 2.3e-06 27.7 0.0 0.0066 16.7 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DUF1188 PF06690.11 EGG15758.1 - 1.1e-05 25.2 0.1 0.0015 18.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) K_oxygenase PF13434.6 EGG15758.1 - 1.8e-05 24.1 0.0 0.14 11.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EGG15758.1 - 3.4e-05 23.1 0.0 0.18 10.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 EGG15758.1 - 6.6e-05 23.2 1.2 0.41 10.9 0.0 2.8 3 0 0 3 3 3 2 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 EGG15758.1 - 7.6e-05 21.7 0.1 0.0059 15.5 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.18 EGG15758.1 - 0.00011 22.4 0.9 0.3 11.3 0.0 2.8 3 0 0 3 3 2 2 TrkA-N domain NAD_binding_9 PF13454.6 EGG15758.1 - 0.00013 22.0 1.6 0.86 9.6 0.0 3.6 2 2 1 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EGG15758.1 - 0.0018 17.1 0.1 0.095 11.4 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.6 EGG15758.1 - 0.0023 18.4 0.2 3.3 8.2 0.0 2.7 3 0 0 3 3 3 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EGG15758.1 - 0.017 14.4 0.0 3.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EGG15758.1 - 0.022 14.0 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain GFO_IDH_MocA PF01408.22 EGG15758.1 - 0.041 14.7 0.1 23 5.8 0.0 3.1 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 EGG15758.1 - 0.084 13.5 1.1 0.46 11.1 0.2 2.6 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent DUF1771 PF08590.10 EGG15759.1 - 8.5e-16 58.1 10.8 8.5e-16 58.1 10.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) CUE PF02845.16 EGG15759.1 - 2.3e-14 52.7 5.6 3.6e-06 26.6 0.1 3.9 3 1 0 3 3 3 2 CUE domain Smr PF01713.21 EGG15759.1 - 3.8e-07 30.4 0.0 8.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Smr domain DMA PF03474.14 EGG15759.1 - 0.00022 20.7 0.2 0.0045 16.5 0.1 2.5 2 0 0 2 2 2 1 DMRTA motif DUF1296 PF06972.11 EGG15759.1 - 0.013 15.6 0.5 7.6 6.8 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) DUF3730 PF12530.8 EGG15760.1 - 9.6e-56 188.9 2.7 9.6e-56 188.9 2.7 4.3 2 1 1 3 3 3 1 Protein of unknown function (DUF3730) HEAT PF02985.22 EGG15760.1 - 2.7e-05 24.0 1.8 18 5.9 0.2 6.1 6 0 0 6 6 6 2 HEAT repeat Imm3 PF14425.6 EGG15760.1 - 0.23 11.5 3.5 0.18 11.8 0.3 2.5 2 0 0 2 2 2 0 Immunity protein Imm3 RhoGEF PF00621.20 EGG15761.1 - 3.1e-40 138.3 1.3 3.1e-40 138.3 1.3 2.5 3 0 0 3 3 3 1 RhoGEF domain PH_6 PF15406.6 EGG15761.1 - 0.00052 20.3 0.0 0.0019 18.5 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_10 PF15411.6 EGG15761.1 - 0.0033 17.7 0.3 0.0033 17.7 0.3 4.5 6 1 0 6 6 6 1 Pleckstrin homology domain IQ PF00612.27 EGG15761.1 - 0.0049 16.5 2.5 0.011 15.4 2.5 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ribosomal_L38e PF01781.18 EGG15761.1 - 0.069 13.3 1.6 0.21 11.7 1.6 1.8 1 0 0 1 1 1 0 Ribosomal L38e protein family PH_16 PF17838.1 EGG15761.1 - 0.096 12.5 0.9 4.3 7.2 0.1 2.9 3 0 0 3 3 3 0 PH domain PH PF00169.29 EGG15761.1 - 0.12 12.9 6.4 0.15 12.6 0.5 3.3 2 1 1 3 3 3 0 PH domain OEP PF02321.18 EGG15761.1 - 5.1 6.9 12.3 2.7 7.8 2.8 2.6 2 0 0 2 2 2 0 Outer membrane efflux protein Beta-lactamase PF00144.24 EGG15762.1 - 1.1e-23 84.0 0.3 8.9e-23 81.0 0.3 2.0 1 1 0 1 1 1 1 Beta-lactamase RhoGAP PF00620.27 EGG15763.1 - 7e-35 120.1 1.7 3.1e-34 118.0 0.2 2.9 3 0 0 3 3 3 1 RhoGAP domain RhoGEF PF00621.20 EGG15763.1 - 3.6e-30 105.6 4.4 2.9e-29 102.6 1.5 2.8 2 0 0 2 2 2 1 RhoGEF domain ATP_transf PF09830.9 EGG15763.1 - 7.7e-20 70.8 0.1 1.7e-19 69.7 0.1 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 EGG15763.1 - 0.0054 16.5 0.2 3.4 7.4 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4922) Abhydrolase_1 PF00561.20 EGG15764.1 - 4.6e-13 49.4 4.1 4.8e-11 42.8 0.0 3.5 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG15764.1 - 4.2e-08 32.8 0.0 7.6e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGG15764.1 - 1.4e-07 31.5 3.6 4.6e-06 26.5 0.1 3.5 3 1 1 4 4 4 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EGG15764.1 - 2.4e-07 31.6 0.0 5.3e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EGG15764.1 - 3e-05 23.9 0.0 7.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 EGG15764.1 - 0.00094 18.7 0.6 0.41 10.1 0.3 2.5 1 1 1 2 2 2 2 Putative serine esterase (DUF676) Ndr PF03096.14 EGG15764.1 - 0.0027 16.5 0.0 0.0027 16.5 0.0 1.9 2 0 0 2 2 2 1 Ndr family Esterase PF00756.20 EGG15764.1 - 0.0048 16.6 0.7 0.015 14.9 0.1 2.1 1 1 2 3 3 3 1 Putative esterase Thioesterase PF00975.20 EGG15764.1 - 0.018 15.1 0.0 0.043 13.9 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Peptidase_S37 PF05576.11 EGG15764.1 - 0.05 12.3 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 PS-10 peptidase S37 Macoilin PF09726.9 EGG15764.1 - 0.11 11.1 10.5 0.11 11.0 10.5 1.1 1 0 0 1 1 1 0 Macoilin family CSRNP_N PF16019.5 EGG15764.1 - 0.23 11.3 2.9 0.49 10.3 2.9 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus INTAP PF16617.5 EGG15764.1 - 0.29 11.5 5.1 0.81 10.1 5.1 1.8 1 0 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region BAT2_N PF07001.11 EGG15764.1 - 0.3 11.5 19.4 0.54 10.7 19.4 1.4 1 0 0 1 1 1 0 BAT2 N-terminus ASD2 PF08687.11 EGG15764.1 - 2.2 7.8 5.3 2.1 7.8 2.7 2.0 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 DUF1635 PF07795.11 EGG15764.1 - 2.3 8.0 10.2 4.6 7.0 10.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) SR-25 PF10500.9 EGG15764.1 - 4.5 6.8 10.6 7.2 6.2 10.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TssN PF17555.2 EGG15765.1 - 0.97 8.8 12.4 1.6 8.0 12.4 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN Zip PF02535.22 EGG15766.1 - 9.8e-35 120.3 9.2 1.5e-33 116.4 9.2 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter MadM PF03818.13 EGG15766.1 - 0.65 9.9 5.1 1.5 8.8 2.5 2.6 1 1 1 2 2 2 0 Malonate/sodium symporter MadM subunit NAP PF00956.18 EGG15767.1 - 5.9e-58 196.2 3.1 7.4e-58 195.8 3.1 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Mst1_SARAH PF11629.8 EGG15767.1 - 0.029 14.5 0.3 0.11 12.6 0.3 2.0 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Ribophorin_I PF04597.14 EGG15768.1 - 6e-123 411.3 7.3 1e-122 410.5 7.3 1.4 1 0 0 1 1 1 1 Ribophorin I FtsX PF02687.21 EGG15768.1 - 4.5 7.8 6.3 2 8.9 1.9 2.2 2 0 0 2 2 2 0 FtsX-like permease family Voldacs PF03517.13 EGG15769.1 - 9.8e-18 64.6 15.5 9.8e-18 64.6 15.5 1.7 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling DUF4611 PF15387.6 EGG15769.1 - 0.027 14.7 1.3 0.027 14.7 1.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) Fumble PF03630.14 EGG15769.1 - 0.039 13.1 0.1 0.052 12.7 0.1 1.3 1 0 0 1 1 1 0 Fumble MDD_C PF18376.1 EGG15769.1 - 0.047 13.4 0.4 0.066 13.0 0.4 1.3 1 0 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain MEA1 PF06910.11 EGG15769.1 - 0.1 13.2 15.2 0.18 12.5 3.2 2.5 2 1 0 2 2 2 0 Male enhanced antigen 1 (MEA1) BUD22 PF09073.10 EGG15769.1 - 1.8 7.8 16.7 2.4 7.4 16.7 1.2 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 EGG15769.1 - 2.8 6.6 5.4 4.2 6.0 5.4 1.2 1 0 0 1 1 1 0 Presenilin S-antigen PF05756.11 EGG15769.1 - 3.3 8.1 14.5 0.33 11.3 1.1 2.5 2 0 0 2 2 2 0 S-antigen protein DUF2982 PF11201.8 EGG15770.1 - 0.028 14.0 0.2 0.54 9.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2982) DUF2981 PF11200.8 EGG15770.1 - 0.029 14.1 3.3 0.033 13.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) CAC1F_C PF16885.5 EGG15770.1 - 0.67 9.6 8.4 0.84 9.2 8.4 1.0 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Macoilin PF09726.9 EGG15770.1 - 0.99 7.9 11.3 1.2 7.6 11.3 1.1 1 0 0 1 1 1 0 Macoilin family MGC-24 PF05283.11 EGG15770.1 - 5.1 7.5 15.2 7.8 6.9 15.2 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TipE PF16972.5 EGG15770.1 - 8.7 5.4 17.1 13 4.9 17.1 1.2 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE DTW PF03942.15 EGG15771.1 - 8.3e-24 84.4 2.9 1.1e-23 84.0 0.0 2.1 1 1 1 2 2 2 1 DTW domain DUF2722 PF10846.8 EGG15771.1 - 0.0013 17.7 2.0 0.0013 17.7 2.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) NAD_binding_1 PF00175.21 EGG15771.1 - 0.32 11.6 2.0 0.67 10.6 2.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain ATP_bind_1 PF03029.17 EGG15772.1 - 5e-80 268.8 0.5 8.2e-80 268.1 0.5 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EGG15772.1 - 8.4e-09 35.3 0.2 2.5e-07 30.4 0.2 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EGG15772.1 - 1.4e-05 24.4 2.7 1.9e-05 24.0 0.0 2.3 2 1 0 3 3 3 1 G-protein alpha subunit Arf PF00025.21 EGG15772.1 - 1.5e-05 24.6 0.1 0.00078 18.9 0.0 2.9 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG15772.1 - 4e-05 23.7 0.0 0.00032 20.7 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 EGG15772.1 - 5.4e-05 22.8 0.0 0.035 13.7 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EGG15772.1 - 5.5e-05 23.6 0.0 0.0002 21.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.18 EGG15772.1 - 0.00015 21.3 0.1 0.003 17.1 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Ras PF00071.22 EGG15772.1 - 0.00021 20.9 0.0 0.75 9.4 0.0 2.6 1 1 1 2 2 2 2 Ras family RsgA_GTPase PF03193.16 EGG15772.1 - 0.00086 19.2 1.0 0.59 10.0 0.0 3.1 4 0 0 4 4 3 1 RsgA GTPase SRPRB PF09439.10 EGG15772.1 - 0.0011 18.4 2.3 0.078 12.4 0.0 2.9 3 0 0 3 3 2 1 Signal recognition particle receptor beta subunit NACHT PF05729.12 EGG15772.1 - 0.0018 18.2 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 EGG15772.1 - 0.0028 16.9 0.1 0.012 14.8 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain MeaB PF03308.16 EGG15772.1 - 0.0046 16.0 0.1 2 7.3 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGG15772.1 - 0.0052 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EGG15772.1 - 0.0077 16.2 0.3 0.07 13.0 0.1 2.4 2 1 0 2 2 2 1 NTPase SRP54 PF00448.22 EGG15772.1 - 0.0083 15.8 0.0 0.048 13.3 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Pox_A32 PF04665.12 EGG15772.1 - 0.0085 15.6 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_18 PF13238.6 EGG15772.1 - 0.0086 16.6 6.5 0.0088 16.6 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 EGG15772.1 - 0.0089 16.0 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EGG15772.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 EGG15772.1 - 0.011 15.4 0.2 0.039 13.7 0.0 2.0 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 EGG15772.1 - 0.012 15.8 0.1 0.032 14.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain Roc PF08477.13 EGG15772.1 - 0.012 15.8 1.6 0.087 13.0 0.0 3.0 3 1 1 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EGG15772.1 - 0.014 15.7 0.0 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGG15772.1 - 0.015 15.0 0.5 0.085 12.6 0.0 2.4 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 EGG15772.1 - 0.023 15.0 0.1 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGG15772.1 - 0.026 13.9 0.1 0.053 12.9 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.6 EGG15772.1 - 0.047 13.9 0.1 0.15 12.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.6 EGG15772.1 - 0.062 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 EGG15772.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_14 PF13173.6 EGG15772.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.8 3 2 1 4 4 3 0 AAA domain ABC_tran PF00005.27 EGG15772.1 - 0.2 12.1 2.4 0.22 12.1 0.0 2.2 2 1 0 2 2 1 0 ABC transporter DUF87 PF01935.17 EGG15772.1 - 0.23 11.6 0.0 0.23 11.6 0.0 2.7 2 1 1 3 3 2 0 Helicase HerA, central domain AAA_21 PF13304.6 EGG15772.1 - 1.1 9.0 4.5 17 5.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system CDK2AP PF09806.9 EGG15772.1 - 8.8 6.3 9.2 0.1 12.6 1.1 1.8 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein AnmK PF03702.14 EGG15773.1 - 5.7e-127 423.8 0.0 6.6e-127 423.6 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Abhydrolase_1 PF00561.20 EGG15774.1 - 1.1e-05 25.3 0.1 1.8e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG15774.1 - 0.00029 21.5 0.0 0.00042 21.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Arm PF00514.23 EGG15775.1 - 0.00013 21.9 0.1 0.19 11.8 0.0 3.6 3 1 0 3 3 3 2 Armadillo/beta-catenin-like repeat DUF4142 PF13628.6 EGG15775.1 - 0.048 13.9 0.0 3.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) Coatomer_WDAD PF04053.14 EGG15776.1 - 3.9e-07 29.5 0.9 0.15 11.1 0.0 4.5 4 1 0 5 5 5 3 Coatomer WD associated region WD40 PF00400.32 EGG15776.1 - 1.7e-05 25.5 0.0 0.27 12.2 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat zf-RING_2 PF13639.6 EGG15777.1 - 1.5e-10 41.2 14.1 2.9e-10 40.3 14.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGG15777.1 - 1.2e-09 37.9 8.4 1.9e-09 37.3 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGG15777.1 - 9.9e-09 35.4 8.0 2.5e-08 34.1 8.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGG15777.1 - 1.6e-08 34.4 10.0 3.5e-08 33.3 10.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG15777.1 - 6.2e-08 32.3 13.9 1.1e-07 31.6 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG15777.1 - 7.8e-08 32.1 11.4 1.4e-07 31.2 11.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGG15777.1 - 3e-07 30.2 14.1 6.1e-07 29.2 14.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG15777.1 - 3.9e-07 29.9 10.8 6.4e-07 29.2 10.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGG15777.1 - 0.00031 20.9 14.3 0.00053 20.1 14.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGG15777.1 - 0.00084 19.2 7.3 0.0017 18.1 7.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EGG15777.1 - 0.0041 17.1 6.9 0.014 15.4 6.9 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 EGG15777.1 - 0.0082 15.8 9.1 0.55 9.9 10.5 2.3 1 1 1 2 2 2 1 P-11 zinc finger U-box PF04564.15 EGG15777.1 - 0.023 14.8 2.5 0.053 13.7 0.1 2.6 2 0 0 2 2 2 0 U-box domain Zn_ribbon_17 PF17120.5 EGG15777.1 - 0.14 11.8 8.7 0.27 10.9 8.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 EGG15777.1 - 0.63 9.9 5.1 1.4 8.8 5.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FTCD_N PF07837.12 EGG15778.1 - 5.9e-73 244.4 0.0 1.1e-72 243.5 0.0 1.5 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD PF02971.14 EGG15778.1 - 1.1e-64 216.9 0.1 2.1e-64 215.9 0.1 1.5 1 0 0 1 1 1 1 Formiminotransferase domain FTCD_C PF04961.12 EGG15778.1 - 6.3e-61 205.3 0.2 1.4e-60 204.2 0.2 1.6 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase PheRS_DBD2 PF18554.1 EGG15778.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Hydrolase_4 PF12146.8 EGG15779.1 - 1.2e-66 224.5 0.0 3.3e-66 223.0 0.0 1.9 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG15779.1 - 1.5e-10 42.1 0.0 3.3e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG15779.1 - 1.9e-10 40.8 0.1 5.2e-09 36.1 0.0 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG15779.1 - 2.8e-05 23.7 1.4 0.00058 19.4 0.4 3.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGG15779.1 - 0.053 13.4 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 EGG15779.1 - 0.058 13.0 0.0 0.058 13.0 0.0 4.9 2 1 3 5 5 5 0 Putative esterase Abhydrolase_2 PF02230.16 EGG15779.1 - 0.088 12.6 0.6 3.8 7.3 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Sec1 PF00995.23 EGG15780.1 - 3.5e-125 419.5 14.2 4.1e-125 419.2 14.2 1.0 1 0 0 1 1 1 1 Sec1 family DUF2802 PF10975.8 EGG15780.1 - 0.061 13.5 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) CdiI_2 PF18593.1 EGG15780.1 - 0.15 12.8 2.9 1.1 9.9 0.2 3.3 4 0 0 4 4 4 0 CdiI immunity protein V-ATPase_H_C PF11698.8 EGG15780.1 - 0.18 11.9 3.2 0.43 10.7 0.4 2.8 1 1 1 2 2 2 0 V-ATPase subunit H RNA_pol_Rpb1_3 PF04983.18 EGG15780.1 - 1.1 9.1 6.7 3 7.8 4.9 2.6 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 3 DUF2935 PF11155.8 EGG15780.1 - 2.7 8.4 5.9 0.78 10.1 0.2 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) Peptidase_M16 PF00675.20 EGG15781.1 - 7.6e-52 175.3 0.0 1.2e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGG15781.1 - 6.6e-33 114.3 0.0 1.4e-32 113.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 EGG15781.1 - 0.0063 15.7 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Dopey_N PF04118.14 EGG15782.1 - 1.1e-73 248.0 1.4 1.1e-73 248.0 1.4 4.2 4 0 0 4 4 4 1 Dopey, N-terminal TFIIA PF03153.13 EGG15782.1 - 0.012 15.6 42.5 0.011 15.8 15.1 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit SRRM_C PF15230.6 EGG15782.1 - 0.13 12.9 1.5 0.25 11.9 0.1 2.2 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus KORA PF16509.5 EGG15782.1 - 9.9 6.5 6.7 0.43 10.9 0.1 2.2 3 0 0 3 3 3 0 TrfB plasmid transcriptional repressor PQ-loop PF04193.14 EGG15783.1 - 1.6e-19 69.4 17.5 4.4e-15 55.2 0.7 3.4 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 EGG15783.1 - 0.00015 22.6 9.7 0.00022 22.1 9.2 1.6 1 1 0 1 1 1 1 ER lumen protein retaining receptor Complex1_LYR PF05347.15 EGG15784.1 - 3.9e-10 39.6 0.0 9.5e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGG15784.1 - 0.0078 16.9 0.0 0.0078 16.9 0.0 2.9 4 0 0 4 4 4 1 Complex1_LYR-like LSM PF01423.22 EGG15785.1 - 1.6e-17 62.9 0.3 1.8e-17 62.7 0.3 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGG15785.1 - 0.038 13.7 0.2 0.056 13.1 0.2 1.3 1 0 0 1 1 1 0 Hfq protein Peptidase_M17 PF00883.21 EGG15786.1 - 3.9e-125 417.2 0.0 6e-125 416.6 0.0 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EGG15786.1 - 1.7e-19 69.9 0.1 4.5e-19 68.6 0.1 1.7 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain ANAPC4_WD40 PF12894.7 EGG15787.1 - 2.4e-05 24.5 0.4 0.073 13.4 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG15787.1 - 0.00067 20.4 6.3 0.21 12.5 0.1 4.5 3 1 0 3 3 3 1 WD domain, G-beta repeat DUF3244 PF11589.8 EGG15787.1 - 0.025 14.6 0.7 0.055 13.6 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) CCCAP PF15964.5 EGG15789.1 - 0.093 11.0 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family DEAD PF00270.29 EGG15789.1 - 0.11 12.2 0.1 0.39 10.5 0.1 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase YqjK PF13997.6 EGG15790.1 - 0.09 13.0 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 YqjK-like protein Xpo1 PF08389.12 EGG15791.1 - 2.8e-22 79.4 2.5 2.8e-22 79.4 2.5 4.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 EGG15791.1 - 1.5e-06 28.1 0.7 9.9e-06 25.4 0.7 2.6 1 1 0 1 1 1 1 Importin-beta N-terminal domain AIM5 PF17050.5 EGG15791.1 - 0.19 12.5 0.9 3.6 8.5 0.2 2.9 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 DUF3430 PF11912.8 EGG15792.1 - 1.8e-16 60.9 22.3 2.2e-16 60.5 22.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGG15792.1 - 0.96 9.7 12.2 0.45 10.8 2.8 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF3586) NAGLU PF05089.12 EGG15793.1 - 2.1e-141 470.7 7.3 2.1e-141 470.7 7.3 2.6 3 0 0 3 3 3 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 EGG15793.1 - 3.8e-73 246.3 11.7 9.4e-73 245.0 11.7 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 EGG15793.1 - 1.8e-13 50.0 0.0 5.1e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain SWIM PF04434.17 EGG15793.1 - 0.0014 18.3 1.0 0.0024 17.5 1.0 1.4 1 0 0 1 1 1 1 SWIM zinc finger Cullin PF00888.22 EGG15794.1 - 1.2e-190 635.3 11.4 1.2e-190 635.3 11.4 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EGG15794.1 - 1e-26 92.8 4.4 1e-26 92.8 4.4 2.4 3 0 0 3 3 3 1 Cullin protein neddylation domain MukF_M PF17192.4 EGG15794.1 - 0.039 13.7 2.5 0.32 10.7 0.5 2.8 2 0 0 2 2 2 0 MukF middle domain IL28A PF15177.6 EGG15794.1 - 0.64 9.8 3.1 0.47 10.3 0.1 2.3 3 0 0 3 3 3 0 Interleukin-28A Mt_ATP-synt_D PF05873.12 EGG15794.1 - 7.6 6.4 9.3 4 7.3 1.2 2.5 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) CBM49 PF09478.10 EGG15795.1 - 1.5e-10 41.2 0.0 2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM49 PF09478.10 EGG15796.1 - 6.1e-13 48.9 0.0 8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF2606 PF10794.9 EGG15796.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) MG3 PF17791.1 EGG15796.1 - 0.035 14.4 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Macroglobulin domain MG3 DUF4354 PF14263.6 EGG15796.1 - 0.053 13.3 0.1 0.09 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) DUF2607 PF10795.9 EGG15796.1 - 0.067 13.3 0.2 0.096 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) CBM49 PF09478.10 EGG15797.1 - 1.4e-13 50.9 0.0 1.9e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF2607 PF10795.9 EGG15797.1 - 0.075 13.2 0.3 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) MG3 PF17791.1 EGG15797.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Macroglobulin domain MG3 VCBS PF13517.6 EGG15798.1 - 0.00015 22.3 2.9 0.77 10.4 0.1 3.8 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.6 EGG15798.1 - 0.001 18.7 0.2 0.13 11.8 0.1 2.7 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 EGG15798.1 - 0.0059 16.5 0.1 0.026 14.4 0.1 2.1 1 0 0 1 1 1 1 PQQ enzyme repeat FG-GAP PF01839.23 EGG15798.1 - 8.9 6.6 10.1 0.55 10.4 0.1 3.0 3 0 0 3 3 3 0 FG-GAP repeat Hormone_1 PF00103.20 EGG15799.1 - 0.11 12.3 1.2 0.13 12.0 1.2 1.0 1 0 0 1 1 1 0 Somatotropin hormone family O-antigen_lig PF13425.6 EGG15799.1 - 0.25 10.1 0.5 0.28 9.9 0.5 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein KHA PF11834.8 EGG15800.1 - 0.042 13.9 0.0 0.045 13.9 0.0 1.1 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel RNA_pol_Rpb1_1 PF04997.12 EGG15800.1 - 0.043 13.2 0.1 0.043 13.2 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EGG15801.1 - 8.4e-109 363.1 0.3 2.3e-108 361.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EGG15801.1 - 8e-107 357.2 0.5 1.9e-106 356.0 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EGG15801.1 - 6.8e-77 257.4 1.4 2.1e-76 255.8 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EGG15801.1 - 1.1e-59 201.5 0.2 2.3e-59 200.5 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EGG15801.1 - 1.9e-51 174.1 0.1 6.8e-51 172.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EGG15801.1 - 3.1e-44 150.3 4.9 1.1e-43 148.5 4.9 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EGG15801.1 - 3.9e-39 132.9 1.0 1.4e-38 131.2 1.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EGG15801.1 - 5.6e-08 32.7 317.8 1.6 9.2 18.2 13.7 13 0 0 13 13 13 12 RNA polymerase Rpb1 C-terminal repeat Pept_tRNA_hydro PF01195.19 EGG15802.1 - 1.4e-11 44.7 0.0 1.9e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Phage_Gp111 PF07410.11 EGG15802.1 - 0.2 12.1 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein SUIM_assoc PF16619.5 EGG15803.1 - 0.025 14.6 5.2 0.025 14.6 5.2 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 EGG15804.1 - 0.037 14.0 43.6 0.056 13.4 43.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Caldesmon PF02029.15 EGG15804.1 - 0.044 12.6 27.7 0.061 12.1 27.7 1.1 1 0 0 1 1 1 0 Caldesmon SWI-SNF_Ssr4 PF08549.10 EGG15804.1 - 7.5 5.1 29.9 10 4.6 29.9 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DSPc PF00782.20 EGG15805.1 - 3e-31 108.0 0.4 1.4e-30 105.9 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG15805.1 - 0.0022 17.6 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGG15805.1 - 0.003 17.7 0.6 0.007 16.5 0.6 1.6 1 1 0 1 1 1 1 Inositol hexakisphosphate SEO_N PF14576.6 EGG15805.1 - 0.0066 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Sieve element occlusion N-terminus Y_phosphatase3 PF13350.6 EGG15805.1 - 0.011 15.7 0.1 0.018 15.0 0.1 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Tex_N PF09371.10 EGG15805.1 - 0.027 14.2 0.9 0.047 13.3 0.9 1.3 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Y_phosphatase2 PF03162.13 EGG15805.1 - 0.049 13.2 0.4 0.088 12.4 0.1 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family CDKN3 PF05706.12 EGG15805.1 - 0.087 12.5 0.1 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) RRP36 PF06102.12 EGG15805.1 - 0.57 10.1 5.4 0.59 10.1 3.4 1.8 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Chromate_transp PF02417.15 EGG15807.1 - 7.8e-21 74.8 30.3 8.6e-19 68.2 15.4 2.5 3 0 0 3 3 3 2 Chromate transporter Phage_holin_3_1 PF05106.12 EGG15807.1 - 7.6 7.0 9.2 33 5.0 5.2 3.3 1 1 1 2 2 2 0 Phage holin family (Lysis protein S) NAGLU_C PF12972.7 EGG15808.1 - 1.8e-73 247.3 5.6 1.8e-73 247.3 5.6 1.6 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU PF05089.12 EGG15808.1 - 4.6e-28 98.1 14.2 5.1e-21 75.0 4.7 3.3 2 1 1 3 3 3 2 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_N PF12971.7 EGG15808.1 - 2e-14 53.1 0.3 7.2e-14 51.3 0.0 2.2 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain SWIM PF04434.17 EGG15808.1 - 0.0071 16.0 0.5 0.013 15.1 0.5 1.5 1 0 0 1 1 1 1 SWIM zinc finger ALMT PF11744.8 EGG15808.1 - 1.9 7.2 8.3 3.6 6.3 8.3 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 EGG15808.1 - 3.7 7.4 21.6 7.3 6.5 21.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Menin PF05053.13 EGG15808.1 - 4.3 5.6 13.6 6.7 4.9 13.6 1.2 1 0 0 1 1 1 0 Menin Pkinase_Tyr PF07714.17 EGG15809.1 - 2.1e-51 174.7 0.0 4e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Myotub-related PF06602.14 EGG15809.1 - 1.2e-45 156.0 2.4 1.2e-45 156.0 2.4 3.4 2 1 0 2 2 2 1 Myotubularin-like phosphatase domain Pkinase PF00069.25 EGG15809.1 - 6e-44 150.4 0.0 1.5e-43 149.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 EGG15809.1 - 1.6e-26 91.8 54.6 2.2e-09 36.9 0.4 7.9 4 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EGG15809.1 - 1.1e-20 73.4 56.8 2.5e-05 24.6 3.0 10.3 8 1 0 9 9 9 6 Leucine Rich repeats (2 copies) RhoGAP PF00620.27 EGG15809.1 - 5.2e-14 52.3 0.1 1.8e-13 50.6 0.1 2.0 1 0 0 1 1 1 1 RhoGAP domain COR PF16095.5 EGG15809.1 - 3.9e-12 46.4 4.8 3.8e-09 36.6 0.3 3.3 3 0 0 3 3 3 2 C-terminal of Roc, COR, domain ABC1 PF03109.16 EGG15809.1 - 0.0084 16.3 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 ABC1 family LRR_1 PF00560.33 EGG15809.1 - 0.0093 16.4 43.3 4.1 8.3 0.4 12.9 12 0 0 12 12 12 2 Leucine Rich Repeat PTE PF02126.18 EGG15810.1 - 3.4e-67 227.0 0.3 4.8e-67 226.5 0.3 1.2 1 0 0 1 1 1 1 Phosphotriesterase family TFIID-31kDa PF02291.15 EGG15810.1 - 0.0091 16.1 1.8 0.36 10.9 0.1 2.3 2 0 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit DUF5341 PF17276.2 EGG15810.1 - 0.034 14.3 0.7 0.05 13.8 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5341) ESM4 PF15952.5 EGG15811.1 - 1 9.8 16.2 0.29 11.5 10.9 2.2 2 0 0 2 2 2 0 Enhancer of split M4 family SET PF00856.28 EGG15812.1 - 4.5e-10 40.2 0.1 7.8e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 EGG15812.1 - 4.9e-05 24.0 0.1 4.9e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding HLH PF00010.26 EGG15812.1 - 0.0049 16.8 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4519 PF15012.6 EGG15812.1 - 0.38 11.0 1.8 1.1 9.5 1.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) NLRC4_HD2 PF17776.1 EGG15815.1 - 0.02 15.4 1.4 6.9 7.2 0.1 3.1 3 0 0 3 3 3 0 NLRC4 helical domain HD2 DUF2671 PF10877.8 EGG15815.1 - 0.04 13.7 0.2 0.11 12.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2671) zf-Di19 PF05605.12 EGG15816.1 - 4.3e-16 58.9 1.4 4.3e-16 58.9 1.4 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding ZZ PF00569.17 EGG15816.1 - 0.00014 21.6 7.1 0.00014 21.6 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, ZZ type SUIM_assoc PF16619.5 EGG15816.1 - 0.0068 16.4 3.4 0.0068 16.4 3.4 4.0 3 1 0 3 3 2 1 Unstructured region C-term to UIM in Ataxin3 zf-B_box PF00643.24 EGG15816.1 - 0.021 15.0 5.0 0.021 15.0 5.0 2.8 2 1 1 3 3 3 0 B-box zinc finger C1_2 PF03107.16 EGG15816.1 - 1.3 9.4 18.6 0.77 10.1 7.4 3.6 4 0 0 4 4 4 0 C1 domain Cwf_Cwc_15 PF04889.12 EGG15816.1 - 1.4 8.6 30.0 0.8 9.4 18.0 3.0 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein zf-H2C2_5 PF13909.6 EGG15816.1 - 1.8 8.4 6.2 1.7 8.5 0.8 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Sigma70_ner PF04546.13 EGG15816.1 - 2.4 8.0 16.8 0.85 9.5 13.4 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-UBR PF02207.20 EGG15816.1 - 3.4 7.9 12.1 9.5 6.5 4.7 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DNA_pol_phi PF04931.13 EGG15816.1 - 6.9 4.6 30.9 0.16 10.0 23.8 1.7 2 0 0 2 2 2 0 DNA polymerase phi zf-C3HC4_3 PF13920.6 EGG15816.1 - 7.6 6.5 13.5 49 3.9 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Sugar_tr PF00083.24 EGG15817.1 - 3.9e-81 273.2 20.6 5.3e-81 272.8 20.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG15817.1 - 3.3e-37 128.2 23.5 3.3e-37 128.2 23.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EGG15817.1 - 3.5e-08 32.3 18.0 9.6e-05 21.0 5.0 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EGG15817.1 - 0.0001 21.7 4.2 0.0001 21.7 4.2 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Nuc_H_symport PF03825.16 EGG15817.1 - 0.00044 19.4 0.4 0.00044 19.4 0.4 2.2 2 0 0 2 2 2 1 Nucleoside H+ symporter DUF2061 PF09834.9 EGG15817.1 - 0.024 15.2 0.6 0.024 15.2 0.6 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) DUF3695 PF12494.8 EGG15818.1 - 0.0067 16.3 0.2 0.014 15.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) MMR_HSR1 PF01926.23 EGG15818.1 - 0.016 15.2 0.0 0.059 13.4 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EGG15818.1 - 0.023 15.2 0.0 0.064 13.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 EGG15818.1 - 0.053 14.0 0.1 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGG15818.1 - 0.057 13.8 0.4 0.32 11.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 EGG15818.1 - 0.057 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EGG15818.1 - 0.13 11.2 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EGG15819.1 - 0.011 16.2 0.1 0.056 14.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 EGG15819.1 - 0.019 15.0 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGG15819.1 - 0.025 15.0 0.3 0.23 11.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 EGG15819.1 - 0.027 14.9 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 EGG15819.1 - 0.048 13.4 0.4 0.14 11.9 0.0 2.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 EGG15819.1 - 0.063 13.7 0.1 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGG15819.1 - 0.1 13.0 0.1 5.7 7.3 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGG15819.1 - 0.15 11.8 0.0 1.1 9.0 0.0 2.5 2 1 0 2 2 2 0 P-loop containing region of AAA domain MeaB PF03308.16 EGG15819.1 - 0.16 10.9 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Tricorn_PDZ PF14685.6 EGG15822.1 - 0.15 12.0 0.2 0.33 11.0 0.2 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Dicty_CAD PF05720.12 EGG15824.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Cell-cell adhesion domain DUF2043 PF09740.9 EGG15825.1 - 6.8e-27 94.2 1.5 2.4e-26 92.5 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2043) Peptidase_C70 PF12385.8 EGG15825.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 EF-hand_13 PF17958.1 EGG15826.1 - 1e-24 86.2 0.4 1.1e-23 82.9 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EGG15826.1 - 7.3e-16 58.4 1.5 7.3e-16 58.4 1.5 4.0 4 2 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 EGG15826.1 - 0.014 15.2 4.5 0.12 12.3 0.3 3.8 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_6 PF13405.6 EGG15826.1 - 0.099 12.6 5.8 0.18 11.8 0.7 3.9 4 0 0 4 4 4 0 EF-hand domain EF-hand_1 PF00036.32 EGG15826.1 - 0.13 11.9 9.4 0.1 12.2 0.6 4.6 5 0 0 5 5 5 0 EF hand SPARC_Ca_bdg PF10591.9 EGG15826.1 - 0.19 12.1 5.8 2.8 8.3 0.4 3.3 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Amidohydro_2 PF04909.14 EGG15827.1 - 6.4e-19 68.8 0.0 1.1e-18 68.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Thymidylate_kin PF02223.17 EGG15828.1 - 3.6e-39 134.4 0.0 4.2e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase Ebp2 PF05890.12 EGG15829.1 - 2.4e-73 247.0 32.1 2.4e-73 247.0 32.1 3.8 2 1 3 5 5 5 1 Eukaryotic rRNA processing protein EBP2 Endonuclease_NS PF01223.23 EGG15830.1 - 2.6e-46 158.3 0.3 3.7e-46 157.8 0.3 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF1248 PF06852.12 EGG15830.1 - 0.025 14.0 0.3 0.059 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1248) Glycos_transf_2 PF00535.26 EGG15831.1 - 7e-36 123.6 0.0 8.5e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGG15831.1 - 8e-15 55.4 0.0 1.1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGG15831.1 - 4.4e-05 23.0 0.0 6.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 EGG15831.1 - 0.0033 16.9 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 EGG15831.1 - 0.033 13.8 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 SPX PF03105.19 EGG15832.1 - 6.1e-05 23.1 5.7 7.3e-05 22.8 5.7 1.1 1 0 0 1 1 1 1 SPX domain Apt1 PF10351.9 EGG15832.1 - 0.0016 17.4 13.0 0.0023 16.9 13.0 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain DUF3439 PF11921.8 EGG15832.1 - 0.002 18.1 5.7 0.0052 16.7 5.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) BUD22 PF09073.10 EGG15832.1 - 0.006 16.0 14.5 0.0082 15.5 14.5 1.1 1 0 0 1 1 1 1 BUD22 Macoilin PF09726.9 EGG15832.1 - 0.0062 15.2 8.8 0.0082 14.8 8.8 1.1 1 0 0 1 1 1 1 Macoilin family SLC12 PF03522.15 EGG15832.1 - 0.0082 15.2 5.1 0.012 14.7 5.1 1.2 1 0 0 1 1 1 1 Solute carrier family 12 eIF-3c_N PF05470.12 EGG15832.1 - 0.035 12.4 4.5 0.053 11.8 4.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mucin PF01456.17 EGG15832.1 - 0.14 12.1 14.6 0.3 11.1 14.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3873 PF12989.7 EGG15832.1 - 0.18 12.2 3.5 15 6.1 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) CDC45 PF02724.14 EGG15832.1 - 0.18 10.0 8.0 0.039 12.3 4.3 1.7 2 0 0 2 2 2 0 CDC45-like protein ATF7IP_BD PF16788.5 EGG15832.1 - 0.9 9.6 20.3 1.4 8.9 20.3 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain Nop14 PF04147.12 EGG15832.1 - 1.3 7.1 9.6 1.9 6.6 9.6 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 EGG15832.1 - 5.3 5.7 10.5 8.1 5.1 10.5 1.2 1 0 0 1 1 1 0 Presenilin DUF4614 PF15391.6 EGG15832.1 - 5.8 6.9 26.6 14 5.6 26.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Sporozoite_P67 PF05642.11 EGG15832.1 - 6.6 4.7 22.7 9.5 4.2 22.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Allexi_40kDa PF05549.11 EGG15833.1 - 0.0078 15.8 5.7 0.011 15.3 5.7 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein DUF4795 PF16043.5 EGG15833.1 - 0.014 15.0 0.7 0.021 14.4 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) KxDL PF10241.9 EGG15833.1 - 0.015 15.5 1.0 0.015 15.5 1.0 1.8 2 1 0 2 2 2 0 Uncharacterized conserved protein APG17 PF04108.12 EGG15833.1 - 0.019 14.1 2.1 0.023 13.9 2.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF4407 PF14362.6 EGG15833.1 - 0.022 14.1 1.5 0.03 13.7 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EGG15833.1 - 0.027 14.5 3.2 0.031 14.3 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COG5 PF10392.9 EGG15833.1 - 0.2 11.8 3.0 0.14 12.3 0.4 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Muted PF14942.6 EGG15833.1 - 0.21 11.9 7.9 0.44 10.9 7.9 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Snapin_Pallidin PF14712.6 EGG15833.1 - 0.27 11.7 10.8 0.13 12.7 3.3 2.4 1 1 1 2 2 2 0 Snapin/Pallidin DASH_Dad2 PF08654.10 EGG15833.1 - 0.4 11.1 6.1 0.73 10.3 6.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 AATF-Che1 PF13339.6 EGG15833.1 - 0.46 11.2 6.2 0.88 10.2 6.2 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor ALMT PF11744.8 EGG15833.1 - 0.53 9.1 6.0 0.62 8.8 6.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TBK1_CCD1 PF18394.1 EGG15833.1 - 0.57 9.7 4.9 3.1 7.3 5.1 1.9 1 1 1 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 DivIVA PF05103.13 EGG15833.1 - 3.5 7.7 7.8 6.6 6.8 7.5 1.6 1 1 0 1 1 1 0 DivIVA protein Fib_alpha PF08702.10 EGG15833.1 - 5.2 7.2 12.1 1.2 9.3 5.7 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ribosomal_S3_C PF00189.20 EGG15834.1 - 5.8e-24 84.4 0.3 1.5e-23 83.1 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EGG15834.1 - 6.6e-10 38.7 0.1 1.4e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 EGG15834.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Coilin N-terminus BRO1 PF03097.18 EGG15835.1 - 7.8e-26 90.8 0.4 1e-25 90.4 0.4 1.0 1 0 0 1 1 1 1 BRO1-like domain NAGLU_N PF12971.7 EGG15835.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain PseudoU_synth_2 PF00849.22 EGG15836.1 - 1.6e-21 77.1 0.3 3e-21 76.2 0.3 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase Methyltransf_11 PF08241.12 EGG15838.1 - 6.2e-05 23.6 0.0 9.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG15838.1 - 0.0016 19.1 0.0 0.0031 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG15838.1 - 0.0035 17.1 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Mito_carr PF00153.27 EGG15839.1 - 1.6e-69 229.9 2.9 2.7e-22 78.5 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EGG15839.1 - 1.8e-21 74.0 8.9 1.3e-05 24.4 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGG15839.1 - 4.1e-20 72.0 10.3 6.1e-10 39.4 0.3 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG15839.1 - 5.1e-19 66.9 10.8 0.00014 21.2 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGG15839.1 - 9.1e-19 65.7 7.6 9e-05 22.1 0.2 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGG15839.1 - 4.6e-11 42.4 7.4 0.029 14.2 0.1 4.4 3 1 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGG15839.1 - 7.2e-11 42.4 0.8 0.00012 22.4 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EGG15839.1 - 0.0027 17.5 2.9 0.58 10.1 0.2 3.4 3 0 0 3 3 3 1 EF hand Dockerin_1 PF00404.18 EGG15839.1 - 0.064 13.4 0.2 13 6.0 0.0 3.1 3 0 0 3 3 3 0 Dockerin type I domain EF-hand_4 PF12763.7 EGG15839.1 - 2.3 8.2 4.6 28 4.7 0.1 3.2 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Laminin_EGF PF00053.24 EGG15840.1 - 0.00012 22.1 23.8 0.1 12.8 13.3 2.9 1 1 1 2 2 2 2 Laminin EGF domain Acetyltransf_9 PF13527.7 EGG15841.1 - 3.3e-09 36.9 0.1 1e-08 35.3 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG15841.1 - 2.1e-07 31.2 0.0 2.3e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG15841.1 - 4.5e-07 29.8 0.1 1.7e-06 28.0 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG15841.1 - 1.2e-06 28.9 0.0 2.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGG15841.1 - 0.00042 20.4 0.1 0.0026 17.9 0.0 2.3 3 0 0 3 3 3 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EGG15841.1 - 0.00088 18.8 0.2 0.0016 18.0 0.2 1.4 1 0 0 1 1 1 1 Putative acetyl-transferase Elong-fact-P_C PF09285.11 EGG15841.1 - 0.075 12.8 0.3 1.9 8.3 0.0 2.8 3 0 0 3 3 3 0 Elongation factor P, C-terminal FR47 PF08445.10 EGG15841.1 - 0.087 12.8 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein DUF2009 PF09418.10 EGG15843.1 - 1.7e-210 699.9 0.7 1.7e-210 699.9 0.7 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 EGG15843.1 - 5e-06 26.6 5.3 8.6e-06 25.8 5.3 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-piccolo PF05715.13 EGG15843.1 - 0.053 13.7 3.1 0.17 12.1 3.1 1.8 1 0 0 1 1 1 0 Piccolo Zn-finger Fez1 PF06818.15 EGG15843.1 - 0.094 13.2 2.1 0.1 13.1 0.1 2.0 2 0 0 2 2 2 0 Fez1 zf-C3HC4_3 PF13920.6 EGG15843.1 - 0.71 9.8 5.6 1.3 8.9 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IMUP PF15761.5 EGG15843.1 - 1.2 9.9 8.0 2.6 8.8 8.0 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Bap31 PF05529.12 EGG15845.1 - 1.3e-21 76.8 3.6 2.8e-21 75.8 3.6 1.5 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EGG15845.1 - 2.6e-07 30.6 17.7 2.6e-07 30.6 17.7 2.1 1 1 1 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain B_lectin PF01453.24 EGG15845.1 - 1.5e-05 25.5 0.2 0.021 15.4 0.0 2.8 2 1 1 3 3 3 2 D-mannose binding lectin Phage_holin_6_1 PF09682.10 EGG15845.1 - 0.013 15.9 3.4 0.5 10.8 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Phage_GPO PF05929.11 EGG15845.1 - 0.27 10.8 10.8 0.44 10.1 10.8 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Borrelia_P83 PF05262.11 EGG15845.1 - 0.83 8.1 16.7 8 4.8 13.8 2.0 2 0 0 2 2 2 0 Borrelia P83/100 protein Peptidase_S49_N PF08496.10 EGG15845.1 - 0.94 9.5 11.0 0.45 10.6 8.2 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal GAS PF13851.6 EGG15845.1 - 1.4 8.3 21.2 0.23 10.8 17.4 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 EGG15845.1 - 1.5 9.5 12.7 2.6 8.7 10.7 2.4 2 1 0 2 2 2 0 Initiation control protein YabA Presenilin PF01080.17 EGG15845.1 - 3.4 6.4 7.2 5.8 5.6 7.2 1.4 1 0 0 1 1 1 0 Presenilin CBM49 PF09478.10 EGG15846.1 - 8.1e-08 32.5 0.0 1.1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF2606 PF10794.9 EGG15846.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) DUF3157 PF11355.8 EGG15846.1 - 0.18 11.4 0.2 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3157) CBM49 PF09478.10 EGG15847.1 - 2.1e-12 47.2 0.0 3.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF2606 PF10794.9 EGG15847.1 - 0.0053 16.5 0.0 0.0068 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2606) DUF2607 PF10795.9 EGG15847.1 - 0.014 15.5 0.1 0.02 15.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) TRAP-gamma PF07074.12 EGG15847.1 - 0.028 14.0 0.2 0.037 13.6 0.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4354 PF14263.6 EGG15847.1 - 0.037 13.9 0.1 0.062 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) MG3 PF17791.1 EGG15847.1 - 0.055 13.7 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Macroglobulin domain MG3 HTH_23 PF13384.6 EGG15848.1 - 0.00087 19.0 0.1 0.0019 17.9 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 EGG15848.1 - 0.0019 17.6 0.0 0.0047 16.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 EGG15848.1 - 0.0029 17.7 0.3 0.0056 16.8 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain VIR_N PF15912.5 EGG15848.1 - 0.0077 15.9 2.5 0.0077 15.9 2.5 9.2 3 2 4 7 7 7 1 Virilizer, N-terminal HTH_29 PF13551.6 EGG15848.1 - 0.021 14.8 0.2 0.043 13.8 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn helix BB_PF PF18063.1 EGG15849.1 - 3.1e-21 75.9 0.0 1.3e-19 70.7 0.0 2.0 2 0 0 2 2 2 2 Beta barrel Pore-forming domain Lactonase PF10282.9 EGG15850.1 - 2.8e-06 26.8 0.2 0.0081 15.5 0.0 2.5 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller WD40 PF00400.32 EGG15850.1 - 5e-06 27.2 1.1 15 6.7 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG15850.1 - 8.8e-05 22.7 0.0 0.24 11.7 0.0 4.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Endotoxin_N PF03945.14 EGG15851.1 - 2.1e-77 259.8 3.9 5.6e-77 258.4 3.9 1.8 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain WD40 PF00400.32 EGG15851.1 - 7.1e-28 96.3 8.4 5.5e-05 23.9 0.0 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG15851.1 - 2.4e-08 34.1 0.1 0.23 11.8 0.0 5.1 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG15851.1 - 0.0096 15.8 0.0 0.34 10.8 0.0 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 EGG15851.1 - 0.022 14.3 0.0 0.82 9.2 0.0 2.4 1 1 2 3 3 3 0 PQQ-like domain PQQ_3 PF13570.6 EGG15851.1 - 0.081 13.4 0.1 11 6.6 0.0 3.8 5 0 0 5 5 5 0 PQQ-like domain Sas10 PF09368.10 EGG15852.1 - 1.7e-15 57.2 9.0 1.7e-15 57.2 9.0 2.9 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EGG15852.1 - 0.004 17.7 0.0 0.004 17.7 0.0 3.0 3 0 0 3 3 3 1 Sas10/Utp3/C1D family AAA_16 PF13191.6 EGG15855.1 - 1.9e-10 41.4 0.0 6.7e-10 39.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain SET PF00856.28 EGG15857.1 - 9.9e-11 42.3 0.1 8.4e-09 36.0 0.1 2.5 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGG15857.1 - 5.4e-10 39.2 10.7 1.3e-09 38.0 10.7 1.7 1 0 0 1 1 1 1 MYND finger Sulfate_transp PF00916.20 EGG15858.1 - 9.7e-106 353.7 27.6 1.7e-105 352.9 27.6 1.4 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGG15858.1 - 3.8e-22 78.1 0.1 8.3e-22 77.0 0.1 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGG15858.1 - 0.0012 19.3 4.7 0.0012 19.3 4.7 3.1 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 EGG15858.1 - 0.077 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 STAS domain NUDIX PF00293.28 EGG15859.1 - 3.1e-10 40.2 0.0 4.7e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF3212 PF11486.8 EGG15859.1 - 0.046 13.7 0.1 0.09 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) T4_deiodinase PF00837.17 EGG15861.1 - 6.4e-13 48.5 0.0 7.9e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Iodothyronine deiodinase RRM_1 PF00076.22 EGG15862.1 - 1.9e-16 59.6 0.7 4.6e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.10 EGG15862.1 - 2.5e-06 27.1 47.6 0.0039 16.6 0.0 2.7 1 1 1 2 2 2 2 BUD22 RRM_5 PF13893.6 EGG15862.1 - 0.016 14.8 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGG15862.1 - 0.048 13.7 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 RRM_7 PF16367.5 EGG15862.1 - 0.082 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif DUF2004 PF09406.10 EGG15863.1 - 0.11 12.8 0.2 0.44 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) E1-E2_ATPase PF00122.20 EGG15864.1 - 3.4e-44 150.5 2.1 3.4e-44 150.5 2.1 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGG15864.1 - 6.9e-37 126.9 7.5 6.9e-37 126.9 7.5 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGG15864.1 - 8e-23 81.8 0.0 9.3e-10 39.1 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG15864.1 - 1.5e-18 66.7 0.0 3.6e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGG15864.1 - 8.1e-11 41.5 0.1 5e-10 38.9 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG15864.1 - 5.2e-05 23.1 3.5 0.0003 20.6 3.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG15864.1 - 0.17 12.3 0.0 17 5.8 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Nucleos_tra2_N PF01773.20 EGG15864.1 - 1.3 9.7 13.6 0.28 11.8 0.2 4.0 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus SprB PF13573.6 EGG15865.1 - 0.17 11.7 0.0 0.17 11.7 0.0 3.8 4 0 0 4 4 4 0 SprB repeat Y_Y_Y PF07495.13 EGG15865.1 - 1 9.3 9.3 12 6.0 0.0 4.7 4 1 1 5 5 5 0 Y_Y_Y domain Membrane_bind PF14564.6 EGG15867.1 - 5.9e-38 129.7 0.5 1.9e-37 128.0 0.2 1.8 2 0 0 2 2 2 1 Membrane binding Podoplanin PF05808.11 EGG15868.1 - 2.8e-05 24.3 0.0 2.8e-05 24.3 0.0 3.9 5 0 0 5 5 5 1 Podoplanin BsuPI PF12690.7 EGG15868.1 - 0.06 13.4 0.6 0.83 9.7 0.0 3.0 3 0 0 3 3 3 0 Intracellular proteinase inhibitor CENP-B_dimeris PF09026.10 EGG15868.1 - 2.8 8.4 10.0 7.4 7.0 10.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AF-4 PF05110.13 EGG15868.1 - 9.1 4.2 8.5 14 3.6 8.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PH PF00169.29 EGG15870.1 - 3.6e-06 27.4 0.2 1.4e-05 25.5 0.2 2.0 1 0 0 1 1 1 1 PH domain DUF5104 PF17117.5 EGG15870.1 - 0.021 15.3 0.6 0.021 15.3 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5104) Ku_PK_bind PF08785.11 EGG15870.1 - 0.044 13.9 0.2 0.14 12.3 0.2 1.9 1 0 0 1 1 1 0 Ku C terminal domain like PH_8 PF15409.6 EGG15870.1 - 0.085 13.2 0.3 16 5.8 0.1 2.8 2 0 0 2 2 2 0 Pleckstrin homology domain PBD PF00786.28 EGG15870.1 - 0.086 13.2 0.7 0.8 10.1 0.1 3.0 3 0 0 3 3 3 0 P21-Rho-binding domain EGF_2 PF07974.13 EGG15871.1 - 5.2e-05 23.5 11.3 5.2e-05 23.5 11.3 1.9 2 0 0 2 2 2 1 EGF-like domain I-EGF_1 PF18372.1 EGG15871.1 - 0.0019 18.3 7.9 0.0037 17.3 7.9 1.5 1 0 0 1 1 1 1 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 EGG15871.1 - 0.011 16.0 7.4 0.033 14.5 7.4 1.7 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGG15871.1 - 0.016 15.8 10.8 0.045 14.4 10.8 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF EB PF01683.18 EGG15871.1 - 0.021 15.1 6.1 0.044 14.1 6.1 1.5 1 0 0 1 1 1 0 EB module DUF3844 PF12955.7 EGG15871.1 - 0.048 13.8 2.7 0.1 12.7 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) CLN3 PF02487.17 EGG15872.1 - 0.0012 18.0 0.8 0.19 10.7 0.1 2.2 2 0 0 2 2 2 2 CLN3 protein CSG2 PF16965.5 EGG15872.1 - 0.0013 17.7 5.0 0.3 10.0 0.8 2.1 2 0 0 2 2 2 2 Ceramide synthase regulator DUF4834 PF16118.5 EGG15872.1 - 0.002 19.1 15.2 0.14 13.1 0.2 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4834) Wzy_C PF04932.15 EGG15872.1 - 0.0044 16.7 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 1 O-Antigen ligase MID_MedPIWI PF18296.1 EGG15872.1 - 0.0066 16.3 7.8 0.36 10.6 1.1 2.3 2 0 0 2 2 2 2 MID domain of medPIWI DUF1980 PF09323.10 EGG15872.1 - 0.057 13.3 0.3 0.057 13.3 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) Tetraspanin PF00335.20 EGG15872.1 - 0.062 13.0 0.6 0.15 11.7 0.2 1.8 2 0 0 2 2 2 0 Tetraspanin family Zip PF02535.22 EGG15872.1 - 0.072 12.3 2.3 0.96 8.6 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4131 PF13567.6 EGG15872.1 - 0.1 12.3 0.9 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Kei1 PF08552.11 EGG15872.1 - 0.52 10.2 12.9 0.095 12.6 4.3 2.6 2 1 1 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 CRA PF06589.11 EGG15872.1 - 4.9 7.3 8.5 1.4 9.1 2.6 2.2 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) DUF3328 PF11807.8 EGG15872.1 - 5.1 6.8 7.3 14 5.3 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Shisa PF13908.6 EGG15872.1 - 8.4 6.6 19.0 0.19 12.0 0.4 2.6 2 2 0 2 2 2 0 Wnt and FGF inhibitory regulator Hydrolase_4 PF12146.8 EGG15873.1 - 2.7e-15 56.3 0.0 7.1e-10 38.6 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG15873.1 - 6.3e-13 49.0 0.0 7.5e-07 29.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 EGG15873.1 - 6.7e-12 45.8 0.0 1.3e-06 28.5 0.0 2.5 2 1 1 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EGG15873.1 - 9.1e-08 31.8 0.0 5.9e-07 29.2 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EGG15873.1 - 1.2e-07 31.6 0.0 1e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EGG15873.1 - 7.9e-07 29.1 0.0 0.069 12.9 0.0 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGG15873.1 - 6.3e-06 27.0 0.0 0.059 14.0 0.0 3.0 1 1 2 3 3 3 2 Alpha/beta hydrolase family AXE1 PF05448.12 EGG15873.1 - 8.3e-05 21.4 0.0 0.0024 16.6 0.0 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 EGG15873.1 - 0.00021 21.1 0.0 0.00049 19.8 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 EGG15873.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein DUF818 PF05677.12 EGG15873.1 - 0.029 13.3 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF1100 PF06500.11 EGG15873.1 - 0.043 12.6 0.0 0.3 9.8 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) PAF-AH_p_II PF03403.13 EGG15873.1 - 0.16 10.5 0.0 0.32 9.5 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF829 PF05705.14 EGG15873.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) EGF_2 PF07974.13 EGG15874.1 - 0.021 15.2 13.5 0.037 14.4 13.5 1.4 1 0 0 1 1 1 0 EGF-like domain DUF249 PF03158.13 EGG15875.1 - 0.013 15.2 0.4 0.11 12.2 0.2 2.3 1 1 1 2 2 2 0 Multigene family 530 protein Ank_4 PF13637.6 EGG15875.1 - 0.11 13.2 0.1 89 3.8 0.0 4.2 4 2 0 4 4 4 0 Ankyrin repeats (many copies) Rad10 PF03834.14 EGG15876.1 - 0.024 14.6 0.9 0.069 13.2 0.7 1.8 1 1 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) MetRS-N PF09635.10 EGG15876.1 - 0.058 13.9 0.1 0.092 13.3 0.1 1.2 1 0 0 1 1 1 0 MetRS-N binding domain EGF_2 PF07974.13 EGG15878.1 - 0.00084 19.7 33.3 0.0083 16.5 10.6 2.7 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGG15878.1 - 0.0048 16.9 26.3 0.013 15.5 7.3 2.6 2 0 0 2 2 2 2 Tenascin EGF domain EB PF01683.18 EGG15878.1 - 0.13 12.6 18.8 0.47 10.8 3.5 2.7 2 0 0 2 2 2 0 EB module hEGF PF12661.7 EGG15878.1 - 2.3 9.0 26.4 7.6 7.3 10.4 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.13 EGG15879.1 - 1.2e-08 35.1 31.7 0.00029 21.1 6.8 2.6 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGG15879.1 - 0.0034 17.4 24.2 0.016 15.3 5.7 2.6 2 0 0 2 2 2 2 Tenascin EGF domain hEGF PF12661.7 EGG15879.1 - 0.024 15.3 27.0 0.22 12.2 8.5 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.27 EGG15879.1 - 0.039 14.3 25.4 0.14 12.5 4.8 2.6 2 0 0 2 2 2 0 EGF-like domain EB PF01683.18 EGG15879.1 - 0.083 13.2 16.9 1.4 9.3 5.2 2.5 2 0 0 2 2 2 0 EB module EGF_2 PF07974.13 EGG15880.1 - 1.5e-07 31.6 35.0 0.0016 18.8 10.0 2.8 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGG15880.1 - 0.00014 21.9 27.2 0.012 15.7 7.1 2.9 2 0 0 2 2 2 2 Tenascin EGF domain DUF3042 PF11240.8 EGG15880.1 - 0.056 13.5 2.2 0.13 12.3 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) hEGF PF12661.7 EGG15880.1 - 0.14 12.8 27.2 1.3 9.8 8.8 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.27 EGG15880.1 - 7.4 7.0 30.9 4 7.8 9.7 2.7 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 EGG15882.1 - 1.9e-06 28.1 31.3 0.0049 17.2 8.5 2.9 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGG15882.1 - 1.6e-05 24.8 33.1 0.00023 21.2 6.0 2.9 3 0 0 3 3 3 2 Tenascin EGF domain Period_C PF12114.8 EGG15882.1 - 0.074 12.6 0.9 0.16 11.6 0.9 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region hEGF PF12661.7 EGG15882.1 - 0.19 12.4 22.3 2.1 9.1 8.0 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.13 EGG15883.1 - 2.9e-08 34.0 33.3 0.00071 19.9 15.3 3.0 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGG15883.1 - 0.00022 21.2 26.6 0.011 15.7 7.1 2.7 2 0 0 2 2 2 2 Tenascin EGF domain EGF PF00008.27 EGG15883.1 - 0.0053 17.0 25.6 0.065 13.6 7.9 3.1 2 0 0 2 2 2 2 EGF-like domain EB PF01683.18 EGG15883.1 - 1.5 9.2 27.9 0.024 14.9 4.5 3.2 3 0 0 3 3 3 0 EB module hEGF PF12661.7 EGG15883.1 - 7.2 7.4 36.8 0.26 12.0 8.9 3.9 4 0 0 4 4 4 0 Human growth factor-like EGF EGF_2 PF07974.13 EGG15884.1 - 3.1e-08 33.8 35.7 0.00061 20.1 17.7 2.8 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGG15884.1 - 0.0002 21.3 27.3 0.011 15.7 7.1 2.7 2 0 0 2 2 2 2 Tenascin EGF domain EGF PF00008.27 EGG15884.1 - 0.045 14.1 30.7 0.34 11.3 13.0 2.8 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 EGG15884.1 - 0.2 12.4 27.8 1.3 9.8 8.8 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF EB PF01683.18 EGG15884.1 - 4.7 7.6 21.8 4 7.8 4.9 2.7 2 0 0 2 2 2 0 EB module SKG6 PF08693.10 EGG15885.1 - 0.0011 18.3 4.6 0.0023 17.3 4.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LRR19-TM PF15176.6 EGG15885.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Trp_oprn_chp PF09534.10 EGG15885.1 - 0.16 11.7 0.7 0.22 11.3 0.7 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EGF_2 PF07974.13 EGG15886.1 - 6.5e-07 29.6 34.2 0.0038 17.6 10.6 2.7 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 EGG15886.1 - 0.00053 20.5 26.7 0.045 14.4 10.7 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF LRR_8 PF13855.6 EGG15886.1 - 0.0057 16.4 0.5 0.0057 16.4 0.5 4.4 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.33 EGG15886.1 - 0.036 14.6 4.5 13 6.8 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat EB PF01683.18 EGG15886.1 - 0.12 12.6 20.8 0.99 9.7 4.5 2.5 2 0 0 2 2 2 0 EB module EGF PF00008.27 EGG15886.1 - 0.17 12.2 29.2 1.6 9.1 10.6 2.6 2 0 0 2 2 2 0 EGF-like domain LRR_4 PF12799.7 EGG15886.1 - 5.1 7.7 17.3 6 7.4 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) EGF_2 PF07974.13 EGG15887.1 - 1.2e-07 31.9 30.3 0.00037 20.8 10.0 2.6 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGG15887.1 - 0.00012 22.0 20.8 0.0026 17.8 7.1 2.5 2 0 0 2 2 2 2 Tenascin EGF domain EGF PF00008.27 EGG15887.1 - 0.038 14.3 29.3 0.92 9.9 9.7 2.7 2 0 0 2 2 2 0 EGF-like domain EB PF01683.18 EGG15887.1 - 0.079 13.3 19.4 0.52 10.6 3.5 2.6 2 0 0 2 2 2 0 EB module hEGF PF12661.7 EGG15887.1 - 1.6 9.5 28.3 0.31 11.7 8.8 3.0 3 0 0 3 3 3 0 Human growth factor-like EGF PCuAC PF04314.13 EGG15888.1 - 0.039 13.7 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Copper chaperone PCu(A)C EGF_2 PF07974.13 EGG15889.1 - 7.4e-05 23.0 37.2 0.0016 18.8 10.0 2.9 3 0 0 3 3 3 2 EGF-like domain EGF_Tenascin PF18720.1 EGG15889.1 - 0.00038 20.4 23.9 0.011 15.7 7.1 2.9 2 0 0 2 2 2 2 Tenascin EGF domain hEGF PF12661.7 EGG15889.1 - 0.26 12.0 29.2 0.35 11.6 7.8 3.1 3 0 0 3 3 3 0 Human growth factor-like EGF DUF3042 PF11240.8 EGG15889.1 - 0.43 10.6 1.6 0.84 9.7 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) EGF PF00008.27 EGG15889.1 - 1.3 9.3 28.4 4 7.8 9.7 2.8 2 0 0 2 2 2 0 EGF-like domain EB PF01683.18 EGG15889.1 - 2 8.7 21.4 1.8 9.0 4.5 2.7 2 0 0 2 2 2 0 EB module DUF4083 PF13314.6 EGG15890.1 - 0.013 15.5 0.5 0.021 14.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF3040 PF11239.8 EGG15890.1 - 0.036 14.3 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Fim-adh_lectin PF09222.10 EGG15890.1 - 0.041 13.4 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain Mid2 PF04478.12 EGG15890.1 - 0.053 13.3 0.1 0.084 12.7 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Protocadherin PF08374.11 EGG15890.1 - 0.072 13.1 2.1 0.11 12.5 0.5 1.8 1 1 1 2 2 2 0 Protocadherin EGF_2 PF07974.13 EGG15892.1 - 3.1e-07 30.7 33.3 0.0034 17.7 14.7 3.1 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGG15892.1 - 0.13 12.3 24.4 0.45 10.6 7.5 2.9 2 0 0 2 2 2 0 Tenascin EGF domain hEGF PF12661.7 EGG15892.1 - 3.6 8.4 39.6 0.049 14.3 10.7 3.9 4 0 0 4 4 4 0 Human growth factor-like EGF EB PF01683.18 EGG15892.1 - 6.1 7.2 28.1 0.86 9.9 5.3 3.2 3 0 0 3 3 3 0 EB module EGF_2 PF07974.13 EGG15893.1 - 0.0042 17.4 11.0 0.0084 16.5 11.0 1.5 1 0 0 1 1 1 1 EGF-like domain DAP3 PF10236.9 EGG15894.1 - 0.00023 20.5 0.0 0.00048 19.4 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 EGG15894.1 - 0.00097 18.3 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.12 EGG15894.1 - 0.0028 17.6 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EGG15894.1 - 0.013 15.4 0.0 0.013 15.4 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EGG15894.1 - 0.079 12.7 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein MeaB PF03308.16 EGG15894.1 - 0.19 10.7 0.0 0.34 9.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Amino_oxidase PF01593.24 EGG15895.1 - 1.5e-38 133.3 0.0 4.2e-36 125.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 EGG15895.1 - 1.5e-35 123.5 0.0 9.4e-35 120.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGG15895.1 - 1.2e-15 57.4 0.0 5e-07 29.9 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGG15895.1 - 1.3e-10 41.1 0.3 2.4e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EGG15895.1 - 2.3e-08 33.6 0.1 8.5e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 EGG15895.1 - 2.9e-08 33.3 0.1 0.0054 16.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGG15895.1 - 3.5e-08 33.0 0.0 0.00039 19.8 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG15895.1 - 4.1e-07 30.5 0.2 0.00066 20.2 0.0 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGG15895.1 - 2.8e-06 26.7 0.1 0.00022 20.5 0.0 2.9 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EGG15895.1 - 5e-06 25.5 0.2 0.00049 18.9 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 EGG15895.1 - 0.00016 21.2 0.0 0.00033 20.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EGG15895.1 - 0.0024 17.0 0.0 0.027 13.6 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EGG15895.1 - 0.0063 15.6 0.0 0.029 13.4 0.0 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein 3HCDH_N PF02737.18 EGG15895.1 - 0.0085 16.0 0.3 0.05 13.5 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EGG15895.1 - 0.012 16.0 0.0 0.05 14.0 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EGG15895.1 - 0.015 14.9 0.5 0.7 9.4 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EGG15895.1 - 0.034 13.8 1.7 0.11 12.1 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 EGG15895.1 - 0.17 11.9 0.5 6.1 6.8 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding LRR_8 PF13855.6 EGG15896.1 - 0.15 11.9 0.2 0.15 11.9 0.2 2.4 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 EGG15896.1 - 0.18 12.3 7.0 0.21 12.1 0.0 3.5 2 1 1 4 4 4 0 Leucine Rich repeats (2 copies) EGF_2 PF07974.13 EGG15897.1 - 0.033 14.5 30.2 0.23 11.8 8.5 2.5 2 0 0 2 2 2 0 EGF-like domain LRR_8 PF13855.6 EGG15897.1 - 0.066 13.0 6.9 5.6 6.8 0.1 3.9 2 1 2 4 4 4 0 Leucine rich repeat F-box-like PF12937.7 EGG15899.1 - 0.11 12.4 0.1 0.45 10.4 0.1 1.9 1 1 0 1 1 1 0 F-box-like Pkinase PF00069.25 EGG15900.1 - 4.4e-22 78.7 2.3 3.8e-11 42.8 0.0 3.0 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG15900.1 - 8.1e-15 54.8 0.5 2e-13 50.2 0.1 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Radial_spoke_3 PF06098.11 EGG15901.1 - 1.5 8.0 12.8 0.26 10.5 8.2 1.9 2 0 0 2 2 2 0 Radial spoke protein 3 Otopetrin PF03189.13 EGG15903.1 - 0.0053 15.6 0.0 0.013 14.4 0.0 1.6 1 1 0 1 1 1 1 Otopetrin DUF2830 PF11125.8 EGG15903.1 - 0.0079 16.2 0.0 0.029 14.3 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2830) DDHD PF02862.17 EGG15903.1 - 0.0088 16.2 5.0 0.0088 16.2 5.0 2.3 2 0 0 2 2 2 1 DDHD domain SR-25 PF10500.9 EGG15903.1 - 0.012 15.2 5.8 0.012 15.2 5.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.10 EGG15903.1 - 0.13 12.3 10.9 0.27 11.3 10.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EPL1 PF10513.9 EGG15903.1 - 0.16 12.4 12.2 0.018 15.4 6.4 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Activator_LAG-3 PF11498.8 EGG15903.1 - 0.36 9.8 39.9 0.31 9.9 37.3 2.0 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SLC12 PF03522.15 EGG15903.1 - 0.38 9.7 13.9 0.032 13.3 7.9 1.9 2 0 0 2 2 2 0 Solute carrier family 12 Neur_chan_memb PF02932.16 EGG15903.1 - 0.61 10.1 6.5 0.25 11.4 3.0 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4175 PF13779.6 EGG15903.1 - 1.1 7.1 24.4 1.7 6.5 24.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Membralin PF09746.9 EGG15903.1 - 1.2 8.2 10.7 4.3 6.3 5.9 2.2 2 0 0 2 2 2 0 Tumour-associated protein FAM60A PF15396.6 EGG15903.1 - 1.7 8.6 10.8 0.55 10.2 4.8 2.3 2 0 0 2 2 2 0 Protein Family FAM60A RPA43_OB PF17875.1 EGG15903.1 - 4.3 8.0 11.7 0.39 11.4 5.9 2.1 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Gti1_Pac2 PF09729.9 EGG15903.1 - 5.1 7.2 13.7 3.2 7.8 7.2 2.7 3 0 0 3 3 3 0 Gti1/Pac2 family Connexin PF00029.19 EGG15903.1 - 6.3 6.5 9.0 16 5.1 9.0 1.6 1 0 0 1 1 1 0 Connexin Hydin_ADK PF17213.3 EGG15903.1 - 7.2 6.8 11.4 4.4 7.5 5.6 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 EGG15903.1 - 7.8 5.1 16.7 0.39 9.4 9.2 2.1 2 0 0 2 2 2 0 Presenilin FNIP PF05725.12 EGG15904.1 - 7.5e-06 26.0 15.2 0.029 14.5 0.1 8.0 6 3 1 7 7 7 2 FNIP Repeat LRR_8 PF13855.6 EGG15904.1 - 0.074 12.8 7.9 0.7 9.7 0.0 5.1 4 1 1 5 5 5 0 Leucine rich repeat SRP14 PF02290.15 EGG15904.1 - 0.16 12.4 3.0 0.47 10.9 3.0 1.9 1 1 0 1 1 1 0 Signal recognition particle 14kD protein HEPN_SAV2148 PF18725.1 EGG15905.1 - 0.032 13.7 3.6 0.046 13.1 3.6 1.2 1 0 0 1 1 1 0 SAV2148-like HEPN MRF_C1 PF13887.6 EGG15905.1 - 0.12 11.6 0.7 0.3 10.3 0.7 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 CoA_transf_3 PF02515.17 EGG15905.1 - 0.12 11.4 3.1 0.15 11.1 3.1 1.1 1 0 0 1 1 1 0 CoA-transferase family III Shugoshin_N PF07558.11 EGG15905.1 - 0.15 11.9 0.5 0.24 11.3 0.5 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region LRR_4 PF12799.7 EGG15907.1 - 0.0058 17.0 2.9 0.0058 17.0 2.9 7.2 8 1 1 9 9 9 2 Leucine Rich repeats (2 copies) SKG6 PF08693.10 EGG15907.1 - 0.054 12.9 2.4 0.64 9.5 0.2 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF3844 PF12955.7 EGG15907.1 - 0.35 11.0 10.7 2.1 8.5 3.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) EGF_2 PF07974.13 EGG15907.1 - 1.4 9.4 35.3 4 7.9 15.1 2.6 2 0 0 2 2 2 0 EGF-like domain LRR_8 PF13855.6 EGG15907.1 - 2.8 7.8 15.1 0.32 10.8 1.0 5.4 6 1 1 7 7 7 0 Leucine rich repeat RTX_C PF08339.10 EGG15908.1 - 0.0063 16.6 0.7 0.009 16.1 0.7 1.2 1 0 0 1 1 1 1 RTX C-terminal domain TsaE PF02367.17 EGG15908.1 - 0.086 12.8 0.2 0.52 10.3 0.0 2.1 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GST_N PF02798.20 EGG15909.1 - 1.4e-10 41.4 0.0 2.9e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGG15909.1 - 5.4e-10 39.5 0.0 8.9e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG15909.1 - 8e-10 38.8 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG15909.1 - 1.9e-09 37.6 0.2 2.9e-09 37.0 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG15909.1 - 6.5e-09 35.7 0.1 1.3e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGG15909.1 - 1.7e-08 34.6 0.0 4e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain EGF_2 PF07974.13 EGG15912.1 - 2.2e-07 31.1 50.4 0.026 14.9 9.0 3.6 3 0 0 3 3 3 3 EGF-like domain LRR_8 PF13855.6 EGG15912.1 - 0.0093 15.7 9.1 4.4 7.1 0.0 6.6 6 0 0 6 6 6 1 Leucine rich repeat CE2_N PF17996.1 EGG15912.1 - 0.041 13.9 0.0 16 5.5 0.0 3.6 3 0 0 3 3 3 0 Carbohydrate esterase 2 N-terminal HHH_3 PF12836.7 EGG15912.1 - 0.052 13.8 0.1 22 5.4 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF3844 PF12955.7 EGG15912.1 - 0.053 13.7 33.0 0.88 9.7 4.4 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3844) TIG PF01833.24 EGG15912.1 - 0.82 9.8 38.2 0.093 12.8 0.4 8.9 9 0 0 9 9 9 0 IPT/TIG domain HCV_NS4a PF01006.20 EGG15912.1 - 1.4 8.8 11.3 19 5.1 0.6 3.8 3 0 0 3 3 3 0 Hepatitis C virus non-structural protein NS4a PapG_N PF03627.13 EGG15913.1 - 0.00074 19.3 0.9 0.0018 18.0 0.2 2.0 2 0 0 2 2 2 1 PapG carbohydrate binding domain SdrD_B PF17210.3 EGG15913.1 - 0.055 13.7 0.0 0.27 11.5 0.0 2.2 1 0 0 1 1 1 0 SdrD B-like domain LRR_8 PF13855.6 EGG15914.1 - 0.45 10.3 4.1 14 5.5 0.5 3.8 3 0 0 3 3 3 0 Leucine rich repeat TIG PF01833.24 EGG15915.1 - 0.0095 16.0 17.6 0.35 11.0 0.2 5.1 4 1 0 4 4 4 3 IPT/TIG domain DUF2850 PF11012.8 EGG15915.1 - 0.065 13.5 0.2 0.51 10.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2850) EGF_2 PF07974.13 EGG15915.1 - 0.13 12.6 8.5 0.32 11.4 8.5 1.7 1 0 0 1 1 1 0 EGF-like domain ABC_sub_bind PF04392.12 EGG15916.1 - 0.0037 16.5 0.3 0.0044 16.3 0.3 1.1 1 0 0 1 1 1 1 ABC transporter substrate binding protein DNA_pol3_beta_2 PF02767.16 EGG15916.1 - 0.048 13.9 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain AmoC PF04896.12 EGG15916.1 - 0.1 11.8 0.9 0.13 11.5 0.9 1.2 1 0 0 1 1 1 0 Ammonia monooxygenase/methane monooxygenase, subunit C TIG PF01833.24 EGG15916.1 - 0.25 11.4 7.0 1.5 8.9 5.2 2.6 2 1 0 2 2 2 0 IPT/TIG domain DUF220 PF02713.14 EGG15917.1 - 0.065 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF220 DUF2850 PF11012.8 EGG15917.1 - 0.32 11.3 3.0 0.16 12.3 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2850) DDE_1 PF03184.19 EGG15919.1 - 1.9e-09 37.4 1.1 4.6e-09 36.2 0.8 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EGG15919.1 - 4.1e-06 26.7 0.8 1e-05 25.5 0.8 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain RNA_pol_Rpb5_C PF01191.19 EGG15919.1 - 0.0088 15.9 1.2 0.015 15.2 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain DUF2603 PF10788.9 EGG15919.1 - 0.038 14.0 1.6 0.096 12.7 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) SR-25 PF10500.9 EGG15920.1 - 2.3 7.8 8.6 3.4 7.2 8.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ank_2 PF12796.7 EGG15921.1 - 7.4e-20 71.3 2.3 7.2e-10 39.3 0.1 6.4 4 1 3 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG15921.1 - 4.4e-13 49.5 4.8 0.00012 22.5 0.1 7.0 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG15921.1 - 1.8e-09 37.1 10.2 0.39 11.4 0.0 9.7 10 1 1 11 11 11 2 Ankyrin repeat Ank_5 PF13857.6 EGG15921.1 - 4.3e-07 30.1 7.7 1.6 9.1 0.0 6.8 5 2 3 8 8 8 3 Ankyrin repeats (many copies) LRR_8 PF13855.6 EGG15921.1 - 8.1e-05 22.3 0.3 0.0054 16.5 0.4 3.2 3 0 0 3 3 3 1 Leucine rich repeat EGF_Tenascin PF18720.1 EGG15921.1 - 0.016 15.2 5.5 0.043 13.9 5.5 1.8 1 0 0 1 1 1 0 Tenascin EGF domain SepZ PF06066.11 EGG15921.1 - 0.063 13.5 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 SepZ SepZ PF06066.11 EGG15922.1 - 7.7e-05 22.8 1.2 0.15 12.3 0.1 3.1 2 0 0 2 2 2 2 SepZ Insulin_TMD PF17870.1 EGG15922.1 - 0.00012 22.0 0.4 0.43 10.7 0.1 2.6 2 0 0 2 2 2 2 Insulin receptor trans-membrane segment EGF_Tenascin PF18720.1 EGG15922.1 - 0.00032 20.6 18.3 0.092 12.8 5.2 2.8 2 0 0 2 2 2 2 Tenascin EGF domain HisKA_4TM PF16926.5 EGG15922.1 - 0.0049 16.5 0.3 0.85 9.2 0.0 2.4 2 0 0 2 2 2 2 Archaeal 4TM region of histidine kinase HRG PF16954.5 EGG15922.1 - 0.041 14.3 8.0 13 6.3 0.2 5.0 5 0 0 5 5 5 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene fn3_5 PF06280.12 EGG15922.1 - 1.8 9.2 12.8 2.5 8.8 1.8 2.9 2 0 0 2 2 2 0 Fn3-like domain EB PF01683.18 EGG15922.1 - 3.9 7.8 18.7 3.5 8.0 4.1 2.5 2 0 0 2 2 2 0 EB module EphA2_TM PF14575.6 EGG15922.1 - 4.9 8.1 6.2 35 5.4 0.9 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LRR_5 PF13306.6 EGG15923.1 - 0.019 14.9 0.7 0.019 14.9 0.7 3.3 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 EGG15923.1 - 0.037 13.8 0.1 0.037 13.8 0.1 4.5 3 1 2 5 5 5 0 Leucine rich repeat EGF_2 PF07974.13 EGG15923.1 - 1.3 9.5 8.3 2.8 8.4 8.3 1.6 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.24 EGG15923.1 - 1.8 8.7 8.3 0.71 10.0 0.1 3.3 3 0 0 3 3 3 0 IPT/TIG domain Membrane_bind PF14564.6 EGG15924.1 - 9.6e-38 129.0 0.0 1.4e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Membrane binding ACP53EA PF06313.11 EGG15925.1 - 0.0072 16.5 1.8 5.9 7.2 0.1 3.2 2 0 0 2 2 2 2 Drosophila ACP53EA protein DUF2428 PF10350.9 EGG15925.1 - 0.041 13.1 0.0 2.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Putative death-receptor fusion protein (DUF2428) Menin PF05053.13 EGG15925.1 - 0.074 11.4 4.4 1.2 7.4 0.3 2.1 2 0 0 2 2 2 0 Menin MsyB PF13984.6 EGG15925.1 - 0.13 12.6 0.1 4.1 7.7 0.0 2.5 2 0 0 2 2 2 0 MsyB protein Corazonin PF17308.2 EGG15925.1 - 1.4 9.3 15.7 2.8 8.3 5.4 3.1 3 0 0 3 3 3 0 Pro-corazonin LisH PF08513.11 EGG15925.1 - 6.1 6.9 7.0 27 4.9 0.0 4.3 4 0 0 4 4 4 0 LisH EGF_2 PF07974.13 EGG15926.1 - 0.0046 17.3 8.1 0.0099 16.2 8.1 1.6 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 EGG15926.1 - 0.0049 17.1 4.0 0.012 15.9 4.0 1.7 1 0 0 1 1 1 1 EB module hEGF PF12661.7 EGG15926.1 - 1.2 9.9 8.3 3.7 8.3 8.3 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF Ras PF00071.22 EGG15928.1 - 1.4e-28 99.6 0.1 1.7e-28 99.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG15928.1 - 1e-08 35.4 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EGG15928.1 - 0.083 12.6 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF148 PF02520.17 EGG15929.1 - 0.054 13.6 0.0 0.1 12.7 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function DUF148 TMEM164 PF14808.6 EGG15930.1 - 8.7e-18 64.6 7.9 1.8e-17 63.5 7.9 1.5 1 1 0 1 1 1 1 TMEM164 family CENP-B_dimeris PF09026.10 EGG15930.1 - 0.0018 18.6 9.3 0.0038 17.6 9.3 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EGG15930.1 - 0.019 13.1 7.0 0.024 12.7 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi RPN2_C PF18004.1 EGG15930.1 - 0.05 13.5 1.5 0.083 12.8 1.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 EGG15930.1 - 0.14 10.4 4.7 0.18 10.0 4.7 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 EGG15930.1 - 0.16 12.0 4.6 0.3 11.1 4.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 EGG15930.1 - 0.43 10.2 4.1 0.85 9.3 4.1 1.5 1 0 0 1 1 1 0 FAM176 family GCIP PF13324.6 EGG15930.1 - 0.92 9.1 3.2 1.4 8.5 3.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CDC45 PF02724.14 EGG15930.1 - 0.94 7.7 4.3 1.3 7.3 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EGG15930.1 - 1.2 8.3 15.7 1.9 7.7 15.7 1.2 1 0 0 1 1 1 0 NOA36 protein PI3K_1B_p101 PF10486.9 EGG15930.1 - 2 6.1 3.7 2.8 5.6 3.7 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit S1FA PF04689.13 EGG15930.1 - 3.7 7.8 7.1 0.6 10.3 0.3 2.8 3 0 0 3 3 3 0 DNA binding protein S1FA Sporozoite_P67 PF05642.11 EGG15930.1 - 4.8 5.2 8.9 6 4.8 8.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4611 PF15387.6 EGG15930.1 - 5.4 7.3 10.1 10 6.4 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Dicty_REP PF05086.12 EGG15930.1 - 8.9 4.1 15.2 12 3.7 15.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AhpC-TSA_2 PF13911.6 EGG15931.1 - 0.00046 20.3 0.0 0.00083 19.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Ank_2 PF12796.7 EGG15932.1 - 8e-12 45.6 2.9 0.039 14.6 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG15932.1 - 1.8e-06 28.4 3.9 5.4 7.7 0.0 5.6 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG15932.1 - 1.4e-05 25.1 5.4 16 6.5 0.0 7.3 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 EGG15932.1 - 1.9e-05 24.9 0.0 9 6.8 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) DUF432 PF04254.13 EGG15932.1 - 0.032 14.4 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF432) SR-25 PF10500.9 EGG15932.1 - 1.8 8.1 10.8 2.9 7.5 10.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 EGG15932.1 - 4.7 8.0 8.4 8 7.2 8.4 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein LIP1 PF15904.5 EGG15933.1 - 0.011 16.0 4.2 0.94 9.9 0.4 2.8 2 0 0 2 2 2 0 LKB1 serine/threonine kinase interacting protein 1 Amnionless PF14828.6 EGG15933.1 - 0.62 8.8 2.5 10 4.8 0.1 2.5 2 0 0 2 2 2 0 Amnionless SPT_ssu-like PF11779.8 EGG15935.1 - 0.0045 16.6 0.3 0.008 15.8 0.3 1.4 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like LRR_8 PF13855.6 EGG15936.1 - 0.0084 15.9 18.8 0.07 12.9 0.5 5.7 5 1 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 EGG15936.1 - 0.11 13.0 22.3 0.16 12.5 0.1 7.7 7 1 1 8 8 8 0 Leucine Rich repeats (2 copies) SKG6 PF08693.10 EGG15936.1 - 0.32 10.4 2.1 0.72 9.3 2.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3844 PF12955.7 EGG15936.1 - 1 9.5 10.7 2.7 8.2 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) RNA_pol_3_Rpc31 PF11705.8 EGG15936.1 - 6.6 6.9 23.0 0.26 11.5 16.8 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 RicinB_lectin_2 PF14200.6 EGG15937.1 - 0.033 14.9 0.4 0.27 12.0 0.1 2.0 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like EGF_2 PF07974.13 EGG15938.1 - 0.0011 19.3 25.5 0.087 13.2 10.1 2.7 2 0 0 2 2 2 2 EGF-like domain LRR_8 PF13855.6 EGG15938.1 - 0.039 13.7 9.4 0.045 13.5 0.4 4.7 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 EGG15938.1 - 0.27 11.9 3.0 1.2e+02 3.8 0.1 5.2 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 EGG15939.1 - 0.0037 17.6 3.5 0.0037 17.6 3.5 6.7 6 2 2 8 8 8 2 Leucine Rich repeats (2 copies) EGF_2 PF07974.13 EGG15939.1 - 0.0043 17.4 37.3 0.056 13.8 15.8 2.8 2 0 0 2 2 2 2 EGF-like domain LRR_8 PF13855.6 EGG15939.1 - 0.0048 16.6 12.6 0.034 13.9 1.2 4.6 4 0 0 4 4 4 2 Leucine rich repeat DUF3844 PF12955.7 EGG15939.1 - 0.01 16.0 15.8 0.24 11.5 2.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) DDE_Tnp_1_7 PF13843.6 EGG15940.1 - 2.2e-15 56.8 0.3 3.7e-14 52.8 0.3 2.1 1 1 0 1 1 1 1 Transposase IS4 Dehydrin PF00257.19 EGG15941.1 - 0.9 10.1 11.8 1.8 9.1 11.8 1.5 1 0 0 1 1 1 0 Dehydrin Polyoma_coat2 PF00761.20 EGG15941.1 - 1.7 8.3 13.4 2.7 7.6 13.4 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein LRR_4 PF12799.7 EGG15942.1 - 2.7e-05 24.4 23.7 0.0082 16.5 0.9 6.9 7 1 0 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG15942.1 - 0.00012 21.7 17.2 0.041 13.6 0.3 5.6 4 1 0 5 5 5 3 Leucine rich repeat EGF_2 PF07974.13 EGG15942.1 - 0.00017 21.9 26.4 0.014 15.8 10.7 2.6 2 0 0 2 2 2 2 EGF-like domain LRR_4 PF12799.7 EGG15943.1 - 0.0057 17.0 16.6 0.028 14.8 2.6 7.0 6 1 2 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG15943.1 - 0.0083 15.9 7.8 6.6 6.6 0.0 4.9 3 1 0 4 4 4 2 Leucine rich repeat EGF_2 PF07974.13 EGG15943.1 - 0.03 14.7 32.4 0.17 12.3 13.9 2.7 2 0 0 2 2 2 0 EGF-like domain DUF3844 PF12955.7 EGG15943.1 - 0.067 13.3 11.3 0.46 10.6 0.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) hEGF PF12661.7 EGG15943.1 - 6.9 7.5 22.1 12 6.7 4.8 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF DUF3844 PF12955.7 EGG15944.1 - 1.8 8.7 15.0 1 9.5 2.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) Secretin_N_2 PF07655.13 EGG15944.1 - 5.4 7.6 17.6 0.37 11.4 10.1 2.9 2 0 0 2 2 2 0 Secretin N-terminal domain EGF_2 PF07974.13 EGG15945.1 - 0.0054 17.1 30.5 0.18 12.2 13.8 2.7 2 0 0 2 2 2 2 EGF-like domain DUF3844 PF12955.7 EGG15945.1 - 0.57 10.3 11.8 1.5 9.0 1.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) LRR_8 PF13855.6 EGG15946.1 - 1.7e-06 27.7 4.2 0.0016 18.1 0.3 3.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGG15946.1 - 3.6e-05 24.0 20.1 0.29 11.6 0.8 7.1 4 2 1 6 6 6 4 Leucine Rich repeats (2 copies) DUF3844 PF12955.7 EGG15946.1 - 0.15 12.2 17.7 0.59 10.3 2.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) EGF_2 PF07974.13 EGG15946.1 - 0.26 11.7 39.0 0.12 12.8 17.0 2.8 2 0 0 2 2 2 0 EGF-like domain LPP20 PF02169.16 EGG15947.1 - 0.018 15.4 2.3 0.029 14.7 0.3 2.0 2 0 0 2 2 2 0 LPP20 lipoprotein Phostensin_N PF13916.6 EGG15947.1 - 1.8 9.0 6.7 0.22 11.9 1.2 2.2 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal TFIIA PF03153.13 EGG15947.1 - 7 6.5 18.6 9 6.2 18.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_4 PF12799.7 EGG15948.1 - 0.016 15.6 3.3 0.016 15.6 3.3 6.0 4 3 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF3844 PF12955.7 EGG15948.1 - 0.52 10.5 13.0 1.4 9.1 2.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) LRR_8 PF13855.6 EGG15948.1 - 0.62 9.9 18.6 0.062 13.1 2.2 4.9 4 1 1 5 5 5 0 Leucine rich repeat EGF_2 PF07974.13 EGG15948.1 - 0.74 10.2 42.9 0.2 12.1 18.2 2.9 3 0 0 3 3 3 0 EGF-like domain LRR_1 PF00560.33 EGG15948.1 - 3.2 8.7 11.4 11 7.0 2.8 5.4 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 EGG15949.1 - 0.00082 19.1 3.6 0.00082 19.1 3.6 3.5 4 0 0 4 4 4 1 Leucine rich repeat EGF_2 PF07974.13 EGG15949.1 - 0.042 14.2 34.9 0.36 11.2 14.9 2.8 2 0 0 2 2 2 0 EGF-like domain DUF3844 PF12955.7 EGG15949.1 - 0.31 11.2 12.8 0.47 10.6 2.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) EGF_Tenascin PF18720.1 EGG15949.1 - 3 8.0 21.8 2.1 8.5 3.8 3.0 2 0 0 2 2 2 0 Tenascin EGF domain DUF3042 PF11240.8 EGG15949.1 - 4.7 7.3 6.3 9.4 6.4 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) LRR_4 PF12799.7 EGG15950.1 - 0.04 14.4 0.7 0.04 14.4 0.7 7.0 8 2 2 10 10 10 0 Leucine Rich repeats (2 copies) EGF_2 PF07974.13 EGG15950.1 - 0.058 13.8 37.0 0.42 11.0 12.7 2.8 2 0 0 2 2 2 0 EGF-like domain LRR_8 PF13855.6 EGG15950.1 - 0.21 11.4 13.9 0.042 13.6 0.6 4.4 3 1 0 3 3 3 0 Leucine rich repeat DUF3844 PF12955.7 EGG15950.1 - 1.2 9.3 11.2 0.5 10.5 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) EGF_2 PF07974.13 EGG15951.1 - 0.044 14.2 39.5 0.078 13.4 17.1 2.6 2 0 0 2 2 2 0 EGF-like domain DUF3844 PF12955.7 EGG15951.1 - 0.25 11.5 14.7 0.81 9.8 3.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) EGF_2 PF07974.13 EGG15952.1 - 2.5e-06 27.7 29.7 0.00078 19.8 14.2 2.7 2 0 0 2 2 2 2 EGF-like domain LRR_8 PF13855.6 EGG15952.1 - 0.00064 19.4 5.6 0.61 9.9 0.1 5.0 4 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 EGG15952.1 - 0.016 15.7 19.5 7.1 7.2 0.0 7.1 5 2 1 7 7 7 0 Leucine Rich repeats (2 copies) DUF3844 PF12955.7 EGG15952.1 - 0.076 13.2 11.9 1.4 9.1 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) DUF3042 PF11240.8 EGG15952.1 - 0.13 12.3 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) hEGF PF12661.7 EGG15952.1 - 3.1 8.6 31.6 0.25 12.0 9.0 3.8 3 0 0 3 3 3 0 Human growth factor-like EGF EGF PF00008.27 EGG15952.1 - 7 7.0 34.2 0.022 15.1 11.1 3.6 4 0 0 4 4 4 0 EGF-like domain EGF_Tenascin PF18720.1 EGG15952.1 - 9.5 6.4 18.7 0.074 13.1 7.2 2.6 2 0 0 2 2 2 0 Tenascin EGF domain EGF_2 PF07974.13 EGG15953.1 - 5.6e-06 26.6 30.7 0.0014 18.9 15.1 2.6 2 0 0 2 2 2 2 EGF-like domain DUF3844 PF12955.7 EGG15953.1 - 0.31 11.2 13.4 1.2 9.3 2.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) GBP_PSP PF02425.15 EGG15955.1 - 0.028 14.0 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide EGF_2 PF07974.13 EGG15956.1 - 2.5e-07 30.9 28.7 8.4e-05 22.8 14.0 2.7 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 EGG15956.1 - 0.0091 16.6 7.1 0.0091 16.6 7.1 3.6 3 0 0 3 3 3 1 Human growth factor-like EGF EGF_Tenascin PF18720.1 EGG15956.1 - 0.012 15.6 6.8 0.012 15.6 6.8 2.6 2 0 0 2 2 2 0 Tenascin EGF domain EGF PF00008.27 EGG15956.1 - 0.02 15.2 10.1 0.02 15.2 10.1 3.0 2 0 0 2 2 2 0 EGF-like domain DUF3844 PF12955.7 EGG15956.1 - 0.1 12.8 11.6 1.6 8.9 2.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) DUF3042 PF11240.8 EGG15956.1 - 0.17 11.9 0.2 0.45 10.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Ribonuclease_3 PF00636.26 EGG15958.1 - 4.4e-05 24.0 0.1 0.00027 21.5 0.0 2.2 2 1 0 2 2 2 1 Ribonuclease III domain Phage_gp53 PF11246.8 EGG15958.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Base plate wedge protein 53 Suf PF05843.14 EGG15959.1 - 8.2e-80 268.9 32.9 2.1e-75 254.4 0.0 5.4 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EGG15959.1 - 1.3e-05 25.6 0.0 16 6.6 0.0 6.2 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG15959.1 - 0.00046 20.2 0.1 2.5 8.5 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat HAT PF02184.16 EGG15959.1 - 0.00048 20.0 0.1 0.11 12.5 0.1 2.9 2 1 0 2 2 2 1 HAT (Half-A-TPR) repeat TPR_15 PF13429.6 EGG15959.1 - 0.0026 17.0 0.0 0.69 9.1 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG15959.1 - 0.089 13.5 0.3 23 5.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_S24 PF00717.23 EGG15960.1 - 1e-08 35.0 0.1 1.7e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Clat_adaptor_s PF01217.20 EGG15964.1 - 3.1e-50 169.8 1.4 3.4e-50 169.7 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Cas_St_Csn2 PF16813.5 EGG15964.1 - 0.0085 15.2 0.8 0.01 15.0 0.8 1.1 1 0 0 1 1 1 1 CRISPR-associated protein Csn2 subfamily St CutC PF03932.14 EGG15965.1 - 9.9e-64 214.5 1.0 2.3e-59 200.3 0.0 2.1 2 0 0 2 2 2 2 CutC family PCNA_N PF00705.18 EGG15966.1 - 2.2e-52 176.1 0.9 6.8e-52 174.5 1.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EGG15966.1 - 1.1e-47 161.4 0.4 1.7e-46 157.6 0.1 2.2 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 EGG15966.1 - 2.5e-08 33.3 1.1 7.5e-06 25.2 1.1 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EGG15966.1 - 1.6e-06 27.8 0.1 1.8e-06 27.6 0.1 1.0 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 EGG15966.1 - 0.024 13.7 0.1 0.055 12.6 0.1 1.7 1 1 0 1 1 1 0 Hus1-like protein Myco_19_kDa PF05481.12 EGG15966.1 - 0.061 13.6 0.1 0.3 11.4 0.0 2.1 1 1 1 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen HAD_2 PF13419.6 EGG15967.1 - 4.2e-12 46.5 2.0 3.3e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG15967.1 - 1.2e-09 38.8 0.2 2.7e-06 27.8 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG15967.1 - 0.00012 22.6 1.0 0.0022 18.4 1.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGG15967.1 - 0.013 15.5 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_3 PF08282.12 EGG15967.1 - 0.068 12.9 3.3 0.87 9.3 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EGG15967.1 - 0.16 11.8 0.2 0.55 10.1 0.1 2.0 2 1 0 2 2 2 0 Acid Phosphatase AMP-binding PF00501.28 EGG15968.1 - 1.1e-77 261.4 0.0 1.5e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG15968.1 - 1.3e-14 54.9 0.4 2.8e-14 53.8 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TraI_2_C PF07515.11 EGG15968.1 - 0.025 14.5 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term ketoacyl-synt PF00109.26 EGG15969.1 - 1e-75 254.6 0.0 3.6e-75 252.8 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG15969.1 - 7e-54 183.5 0.0 2.1e-53 181.9 0.0 1.9 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EGG15969.1 - 2.5e-37 128.5 0.0 4.8e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGG15969.1 - 1.3e-36 126.4 0.0 4.5e-36 124.6 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EGG15969.1 - 4.1e-30 104.2 0.0 1.3e-29 102.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Chal_sti_synt_C PF02797.15 EGG15969.1 - 7e-23 81.3 0.0 2.2e-22 79.7 0.0 2.0 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 EGG15969.1 - 2.4e-17 63.1 0.3 5.4e-17 62.0 0.3 1.6 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ADH_zinc_N PF00107.26 EGG15969.1 - 4.2e-17 62.3 0.0 2.3e-16 60.0 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGG15969.1 - 2.9e-12 47.8 0.0 1.4e-11 45.6 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAE1_CUT1_RppA PF08392.12 EGG15969.1 - 4e-10 39.5 0.1 4e-10 39.5 0.1 2.1 3 0 0 3 3 3 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 EGG15969.1 - 2.9e-09 37.0 0.1 2.2e-07 30.9 0.0 3.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal PP-binding PF00550.25 EGG15969.1 - 5.6e-09 36.2 0.0 1.3e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EGG15969.1 - 7e-09 36.1 0.1 3.2e-08 34.0 0.1 2.3 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 EGG15969.1 - 1.2e-06 28.3 0.1 4.5e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGG15969.1 - 1.3e-06 28.0 0.9 2e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EGG15969.1 - 1.6e-05 24.6 1.5 0.041 13.8 0.1 3.0 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.25 EGG15969.1 - 0.0012 18.3 0.0 0.004 16.6 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Mid2 PF04478.12 EGG15970.1 - 0.014 15.3 0.1 0.035 13.9 0.1 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EGF_2 PF07974.13 EGG15970.1 - 0.026 14.9 8.8 0.06 13.7 8.8 1.6 1 0 0 1 1 1 0 EGF-like domain EB PF01683.18 EGG15970.1 - 0.076 13.3 5.0 0.16 12.3 5.0 1.5 1 0 0 1 1 1 0 EB module TIG PF01833.24 EGG15970.1 - 0.23 11.6 12.2 1.5 9.0 0.9 4.2 3 1 1 4 4 4 0 IPT/TIG domain LRR_4 PF12799.7 EGG15970.1 - 1.5 9.4 13.2 5.2 7.6 0.0 5.7 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) Mid2 PF04478.12 EGG15971.1 - 0.011 15.6 0.0 0.035 14.0 0.0 1.8 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TIG PF01833.24 EGG15971.1 - 0.024 14.7 9.3 0.071 13.2 6.7 2.8 2 0 0 2 2 2 0 IPT/TIG domain Protocadherin PF08374.11 EGG15971.1 - 0.048 13.6 0.1 0.094 12.7 0.1 1.5 1 0 0 1 1 1 0 Protocadherin EGF_2 PF07974.13 EGG15971.1 - 2.7 8.4 16.4 0.056 13.8 8.8 2.1 2 0 0 2 2 2 0 EGF-like domain DUF2970 PF11174.8 EGG15971.1 - 8.2 6.4 6.5 0.6 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Protocadherin PF08374.11 EGG15972.1 - 0.021 14.8 0.6 0.21 11.6 0.1 2.2 2 0 0 2 2 2 0 Protocadherin LRR_4 PF12799.7 EGG15972.1 - 0.033 14.6 11.6 0.16 12.5 0.3 4.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) EGF_2 PF07974.13 EGG15972.1 - 0.047 14.1 8.3 0.14 12.5 8.3 1.8 1 0 0 1 1 1 0 EGF-like domain Mid2 PF04478.12 EGG15972.1 - 0.053 13.4 0.0 0.053 13.4 0.0 2.1 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor TIG PF01833.24 EGG15972.1 - 0.1 12.7 17.5 0.064 13.3 5.3 4.3 4 0 0 4 4 4 0 IPT/TIG domain LRR19-TM PF15176.6 EGG15972.1 - 0.16 12.0 0.2 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain LRR_8 PF13855.6 EGG15972.1 - 0.16 11.7 7.4 5.8 6.8 0.2 4.2 5 0 0 5 5 5 0 Leucine rich repeat Ni_hydr_CYTB PF01292.20 EGG15972.1 - 0.32 10.6 3.8 0.29 10.7 0.1 2.4 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 DUF2970 PF11174.8 EGG15972.1 - 0.73 9.7 4.8 1.6 8.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) TIG PF01833.24 EGG15973.1 - 0.013 15.6 18.7 0.055 13.5 2.9 4.3 4 0 0 4 4 4 0 IPT/TIG domain EGF_2 PF07974.13 EGG15973.1 - 0.039 14.3 8.3 0.081 13.3 8.3 1.5 1 0 0 1 1 1 0 EGF-like domain EMP70 PF02990.16 EGG15974.1 - 4.4e-153 510.7 18.6 4.4e-153 510.7 18.6 2.3 2 1 0 2 2 2 1 Endomembrane protein 70 Mid2 PF04478.12 EGG15974.1 - 0.0079 16.0 0.3 0.0079 16.0 0.3 2.2 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF4064 PF13273.6 EGG15974.1 - 0.0089 16.3 1.0 0.0089 16.3 1.0 4.3 3 1 0 3 3 3 1 Protein of unknown function (DUF4064) DUF2970 PF11174.8 EGG15974.1 - 0.36 10.7 0.1 0.36 10.7 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) Protocadherin PF08374.11 EGG15974.1 - 0.45 10.5 2.5 0.39 10.7 0.4 1.8 2 0 0 2 2 2 0 Protocadherin EphA2_TM PF14575.6 EGG15974.1 - 1.1 10.1 5.6 21 6.1 0.8 4.1 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF5305 PF17231.2 EGG15974.1 - 4.8 6.5 9.3 13 5.1 0.0 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5305) WD40 PF00400.32 EGG15975.1 - 2.8e-38 129.2 22.9 2e-05 25.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG15975.1 - 2.8e-12 46.8 0.0 0.057 13.7 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG15975.1 - 3.1e-05 23.4 0.0 7.9e-05 22.1 0.0 1.8 2 1 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 EGG15975.1 - 0.026 13.2 0.3 2.4 6.7 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 CRF PF00473.17 EGG15975.1 - 0.29 11.2 0.8 0.55 10.3 0.8 1.3 1 0 0 1 1 1 0 Corticotropin-releasing factor family RRM_1 PF00076.22 EGG15976.1 - 7.5e-20 70.5 0.1 1.3e-19 69.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EGG15976.1 - 0.082 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain HhH-GPD PF00730.25 EGG15977.1 - 4.1e-22 78.7 0.0 8.9e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGG15977.1 - 1.8e-05 24.4 0.0 4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RNA_polI_A34 PF08208.11 EGG15977.1 - 0.008 16.3 16.3 0.008 16.3 16.3 2.3 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 EndIII_4Fe-2S PF10576.9 EGG15977.1 - 0.097 13.0 5.5 0.16 12.3 5.5 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III DUF4604 PF15377.6 EGG15977.1 - 3.8 7.9 30.8 0.21 12.0 18.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Ndc1_Nup PF09531.10 EGG15977.1 - 8.9 4.9 6.4 11 4.5 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDHD PF02862.17 EGG15978.1 - 1e-24 88.0 28.4 6.4e-22 78.8 6.2 4.2 3 1 1 4 4 4 4 DDHD domain E1-E2_ATPase PF00122.20 EGG15979.1 - 5.9e-50 169.3 4.5 5.9e-50 169.3 4.5 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGG15979.1 - 9e-47 160.1 0.4 1.5e-46 159.4 0.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGG15979.1 - 5.8e-26 90.7 0.8 1.2e-13 51.3 0.0 2.9 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EGG15979.1 - 0.00041 20.2 2.5 0.0022 17.8 0.9 2.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGG15979.1 - 0.015 15.3 0.1 0.13 12.3 0.0 2.5 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG15979.1 - 0.026 14.9 0.0 0.079 13.3 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3446 PF11928.8 EGG15981.1 - 0.1 12.9 6.6 0.24 11.7 6.6 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain SR-25 PF10500.9 EGG15981.1 - 0.2 11.2 10.3 0.32 10.6 10.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PHP PF02811.19 EGG15982.1 - 5.1e-10 39.9 0.0 6.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 PHP domain Arf PF00025.21 EGG15983.1 - 2.7e-46 157.2 0.1 1e-45 155.3 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG15983.1 - 8.1e-07 29.3 0.2 8.1e-07 29.3 0.2 2.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGG15983.1 - 0.0002 20.9 0.0 0.0011 18.5 0.0 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 EGG15983.1 - 0.00056 20.3 0.4 0.0062 17.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 EGG15983.1 - 0.0013 18.4 0.2 0.0013 18.4 0.2 2.5 3 1 0 3 3 3 1 Ras family AAA_24 PF13479.6 EGG15983.1 - 0.0062 16.3 0.7 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGG15983.1 - 0.014 15.4 0.2 0.32 10.9 0.2 2.3 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EGG15983.1 - 0.086 13.1 0.1 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain SUZ PF12752.7 EGG15984.1 - 0.0018 19.0 0.2 0.0018 19.0 0.2 4.4 4 1 1 5 5 5 1 SUZ domain DUF4482 PF14818.6 EGG15984.1 - 0.97 10.3 6.1 0.54 11.1 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) TIG PF01833.24 EGG15985.1 - 4.7e-06 26.6 13.5 0.0051 16.9 0.2 4.0 4 0 0 4 4 4 2 IPT/TIG domain EGF_2 PF07974.13 EGG15985.1 - 3.7e-05 24.0 14.3 8.4e-05 22.9 14.3 1.6 1 0 0 1 1 1 1 EGF-like domain LRR_8 PF13855.6 EGG15985.1 - 0.11 12.3 7.6 0.64 9.8 0.2 3.7 3 0 0 3 3 3 0 Leucine rich repeat Laminin_EGF PF00053.24 EGG15985.1 - 0.98 9.6 6.1 2.4 8.4 6.1 1.6 1 0 0 1 1 1 0 Laminin EGF domain LRR_4 PF12799.7 EGG15985.1 - 3.8 8.1 25.5 14 6.2 5.5 6.6 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) EGF PF00008.27 EGG15985.1 - 6.3 7.2 10.6 16 5.9 10.6 1.7 1 0 0 1 1 1 0 EGF-like domain EHN PF06441.12 EGG15986.1 - 0.00086 19.6 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus SIN1 PF05422.12 EGG15986.1 - 0.016 15.7 1.2 0.024 15.2 1.2 1.2 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) Vfa1 PF08432.10 EGG15986.1 - 0.022 15.1 2.9 0.027 14.8 2.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Gemini_AL2 PF01440.16 EGG15986.1 - 0.054 13.9 1.2 0.099 13.1 1.2 1.4 1 0 0 1 1 1 0 Geminivirus AL2 protein Corazonin PF17308.2 EGG15986.1 - 0.26 11.7 7.2 0.5 10.7 7.2 1.5 1 0 0 1 1 1 0 Pro-corazonin ChaC PF04752.12 EGG15987.1 - 1.3e-52 178.4 0.0 1.9e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein PUA PF01472.20 EGG15987.1 - 8.8e-18 64.0 0.0 1.4e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 PUA domain PUA_3 PF17785.1 EGG15987.1 - 0.037 13.9 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 PUA-like domain AIG2_2 PF13772.6 EGG15987.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 AIG2-like family ABC_tran PF00005.27 EGG15989.1 - 6.9e-31 107.6 0.0 6.9e-31 107.6 0.0 2.0 2 1 0 2 2 2 1 ABC transporter SbcCD_C PF13558.6 EGG15989.1 - 0.015 15.5 0.1 0.31 11.3 0.1 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EGG15989.1 - 1.3 9.5 4.3 28 5.1 3.0 3.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Man-6-P_recep PF02157.15 EGG15990.1 - 1.4e-06 27.6 1.2 1.7e-06 27.3 1.2 1.0 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Secretin_N_2 PF07655.13 EGG15991.1 - 0.1 13.2 0.2 0.1 13.2 0.2 3.8 3 1 1 4 4 4 0 Secretin N-terminal domain AAA_35 PF14516.6 EGG15992.1 - 0.0014 17.5 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain Porin_3 PF01459.22 EGG15993.1 - 3.9e-28 98.7 2.5 4.6e-28 98.4 2.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin NtCtMGAM_N PF16863.5 EGG15993.1 - 0.00085 19.5 0.1 0.0019 18.4 0.0 1.6 1 1 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Candida_ALS_N PF11766.8 EGG15993.1 - 0.024 13.9 1.7 0.037 13.3 1.7 1.3 1 1 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding Peroxin-3 PF04882.12 EGG15994.1 - 4.6e-31 108.3 10.3 6.3e-31 107.9 10.3 1.2 1 0 0 1 1 1 1 Peroxin-3 Ribosomal_L23 PF00276.20 EGG15994.1 - 7.7e-13 48.6 3.7 7.7e-13 48.6 3.7 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 EGG15994.1 - 1.8e-12 47.3 6.9 4.1e-12 46.1 6.9 1.7 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain YokU PF14122.6 EGG15994.1 - 0.071 13.1 0.6 0.2 11.6 0.1 2.0 2 0 0 2 2 2 0 YokU-like protein, putative antitoxin G-patch PF01585.23 EGG15995.1 - 2.2e-07 30.6 0.6 6e-07 29.3 0.6 1.7 1 0 0 1 1 1 1 G-patch domain PAC4 PF16093.5 EGG15995.1 - 1 9.6 4.7 42 4.4 4.2 3.1 1 1 1 2 2 2 0 Proteasome assembly chaperone 4 SEP PF08059.13 EGG15996.1 - 3.4e-26 91.6 0.2 1.2e-25 89.9 0.0 2.0 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 EGG15996.1 - 6.4e-13 48.7 0.1 1.3e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EGG15996.1 - 6.5e-11 41.9 0.4 1.3e-10 40.9 0.4 1.6 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 EGG15996.1 - 0.037 13.7 0.3 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 TAP C-terminal domain SR-25 PF10500.9 EGG15996.1 - 6.8 6.2 28.2 0.056 13.1 9.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.13 EGG15996.1 - 9.8 6.8 15.2 8.2 7.1 2.7 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ArsA_ATPase PF02374.15 EGG15997.1 - 1.9e-104 349.1 1.4 2.8e-104 348.6 1.4 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EGG15997.1 - 4.2e-11 43.1 1.5 9.2e-11 42.0 0.1 2.2 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 EGG15997.1 - 1.3e-10 41.4 1.8 4.4e-10 39.7 1.8 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EGG15997.1 - 6.7e-07 29.0 3.1 0.00053 19.5 0.2 3.1 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EGG15997.1 - 9.9e-06 25.2 0.2 2.6e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 EGG15997.1 - 5e-05 22.9 0.1 0.00018 21.1 0.0 1.9 3 0 0 3 3 3 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 EGG15997.1 - 0.00093 18.9 0.2 0.0043 16.7 0.1 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.22 EGG15997.1 - 0.0031 16.7 0.1 0.0067 15.6 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 EGG15997.1 - 0.0094 15.5 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Erf4 PF10256.9 EGG15997.1 - 0.019 15.1 0.2 0.51 10.5 0.0 2.8 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family PhoH PF02562.16 EGG15997.1 - 0.029 13.8 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 EGG15997.1 - 0.09 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MipZ PF09140.11 EGG15997.1 - 0.11 11.7 0.8 0.49 9.6 0.3 2.2 2 1 0 2 2 2 0 ATPase MipZ TFIIA PF03153.13 EGG15998.1 - 0.26 11.3 21.4 0.28 11.1 21.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAA_hydrolase PF01557.18 EGG15998.1 - 0.67 9.6 2.4 2.4 7.8 2.4 1.8 1 1 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family PAT1 PF09770.9 EGG15998.1 - 2.4 6.3 14.3 2.5 6.2 14.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ketoacyl-synt_2 PF13723.6 EGG15998.1 - 3.2 7.3 8.0 4.2 6.9 8.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain FNIP PF05725.12 EGG16000.1 - 1.6e-07 31.4 29.1 0.0095 16.1 0.2 9.1 9 1 1 10 10 10 5 FNIP Repeat DEAD PF00270.29 EGG16001.1 - 9.9e-38 129.6 0.5 2.4e-37 128.4 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG16001.1 - 1.1e-22 80.4 0.2 5.4e-22 78.2 0.2 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG16001.1 - 3.2e-11 43.5 0.1 1.8e-10 41.1 0.0 2.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGG16001.1 - 0.00024 20.9 0.0 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EGG16001.1 - 0.013 15.8 1.2 0.42 10.9 0.5 3.1 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 EGG16001.1 - 0.058 12.9 1.9 0.37 10.2 0.0 2.6 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain F-box-like PF12937.7 EGG16002.1 - 6.1e-14 51.6 2.0 1.1e-13 50.8 2.0 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 EGG16002.1 - 2.7e-07 31.1 4.8 0.007 17.2 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box PF00646.33 EGG16002.1 - 3.7e-07 29.8 4.1 1.1e-06 28.4 4.1 1.8 1 0 0 1 1 1 1 F-box domain SR-25 PF10500.9 EGG16002.1 - 0.0004 20.1 9.6 0.0004 20.1 9.6 3.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein WD40_like PF17005.5 EGG16002.1 - 0.029 13.7 0.3 0.14 11.5 0.1 2.0 2 0 0 2 2 2 0 WD40-like domain ANAPC4_WD40 PF12894.7 EGG16002.1 - 0.043 14.1 0.0 0.16 12.3 0.0 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGG16002.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region DUF3439 PF11921.8 EGG16002.1 - 1.5 8.8 6.6 5.1 7.1 6.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PIP5K PF01504.18 EGG16003.1 - 2.9e-71 239.9 2.4 2.9e-71 239.9 2.4 3.1 3 1 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase CHIP_TPR_N PF18391.1 EGG16003.1 - 7.9 7.3 14.4 4.9 8.0 10.0 2.9 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain SdrD_B PF17210.3 EGG16004.1 - 2.3e-33 114.8 1.7 4.1e-16 59.2 0.8 2.5 2 0 0 2 2 2 2 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG16004.1 - 2.8e-12 46.7 0.2 9.3e-06 25.8 0.1 2.4 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EGG16004.1 - 4.4e-05 23.7 0.1 0.032 14.5 0.1 2.4 2 0 0 2 2 2 2 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 EGG16004.1 - 0.00054 19.9 0.2 0.47 10.5 0.1 2.6 2 0 0 2 2 2 2 CarboxypepD_reg-like domain MetallophosN PF16371.5 EGG16004.1 - 0.0026 18.0 1.1 0.012 15.8 0.4 2.3 2 0 0 2 2 2 1 N terminal of Calcineurin-like phosphoesterase UDP-g_GGTase PF06427.11 EGG16004.1 - 0.0031 17.6 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Dioxygenase_C PF00775.21 EGG16004.1 - 0.022 14.2 0.2 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 Dioxygenase bMG3 PF11974.8 EGG16004.1 - 0.097 12.7 0.0 20 5.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial alpha-2-macroglobulin MG3 domain FAP PF07174.11 EGG16004.1 - 1.5 8.2 18.2 2.3 7.6 18.2 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Ribonuc_L-PSP PF01042.21 EGG16005.1 - 2.8e-24 85.4 0.0 4.7e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP TPR_12 PF13424.6 EGG16006.1 - 7.4e-14 51.8 5.0 1.7e-06 28.2 0.4 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG16006.1 - 1.5e-13 49.7 1.1 0.0047 16.9 0.4 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG16006.1 - 1.2e-12 48.2 2.4 1.6e-05 25.3 0.1 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGG16006.1 - 6.6e-12 44.9 4.1 0.00022 21.4 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG16006.1 - 3e-11 42.6 6.0 0.00057 19.9 0.6 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGG16006.1 - 1e-09 37.7 4.1 0.0042 17.0 0.2 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG16006.1 - 4e-09 36.5 0.0 0.26 12.2 0.0 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG16006.1 - 1.2e-08 35.4 0.0 0.01 16.5 0.0 3.7 3 2 1 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGG16006.1 - 1.6e-08 34.0 6.2 0.083 12.8 0.0 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGG16006.1 - 3.7e-07 30.3 2.5 0.56 11.0 0.1 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG16006.1 - 2.4e-06 27.1 1.0 0.0014 18.2 0.0 4.2 5 1 1 6 6 5 1 TPR repeat TPR_10 PF13374.6 EGG16006.1 - 0.00032 20.5 1.5 1.6 8.7 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 EGG16006.1 - 0.00061 20.1 1.2 0.0086 16.4 0.4 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGG16006.1 - 0.00063 19.0 1.0 0.14 11.4 0.4 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.6 EGG16006.1 - 0.0011 18.5 0.3 0.0011 18.5 0.3 1.7 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP ChAPs PF09295.10 EGG16006.1 - 0.0013 17.8 0.1 0.0049 15.9 0.1 1.7 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF5588 PF17826.1 EGG16006.1 - 0.017 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5588) PPR PF01535.20 EGG16006.1 - 0.02 15.1 0.1 0.45 10.9 0.0 2.5 2 0 0 2 2 2 0 PPR repeat TOM20_plant PF06552.12 EGG16006.1 - 0.02 14.6 4.0 0.22 11.2 0.6 3.3 1 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Mad3_BUB1_I PF08311.12 EGG16006.1 - 0.03 14.3 0.4 4.7 7.2 0.1 2.7 2 1 0 2 2 2 0 Mad3/BUB1 homology region 1 BTAD PF03704.17 EGG16006.1 - 0.043 14.2 0.0 0.12 12.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial transcriptional activator domain Sel1 PF08238.12 EGG16006.1 - 0.25 12.1 9.1 29 5.5 0.0 4.7 4 1 1 5 5 5 0 Sel1 repeat MIT PF04212.18 EGG16006.1 - 0.5 10.5 9.4 0.72 10.0 0.4 3.3 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Adaptin_N PF01602.20 EGG16007.1 - 0.00035 19.3 0.6 0.00057 18.6 0.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGG16007.1 - 0.00082 19.5 0.2 0.0067 16.5 0.0 2.4 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Ribosomal_L6e PF01159.19 EGG16007.1 - 0.0058 17.1 12.2 0.19 12.3 1.7 2.5 2 0 0 2 2 2 2 Ribosomal protein L6e HEAT_2 PF13646.6 EGG16007.1 - 0.008 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 EGG16007.1 - 0.027 14.7 0.0 0.088 13.1 0.0 1.9 1 0 0 1 1 1 0 HEAT repeat Mucin PF01456.17 EGG16007.1 - 1.2 9.2 6.6 2.1 8.3 6.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4834 PF16118.5 EGG16007.1 - 2.5 9.1 12.6 6.7 7.7 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) BORG_CEP PF14957.6 EGG16007.1 - 4.4 8.5 8.9 5.9 8.1 2.3 2.5 2 0 0 2 2 2 0 Cdc42 effector Spt5_N PF11942.8 EGG16008.1 - 0.29 12.1 9.4 0.096 13.7 5.9 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ALMT PF11744.8 EGG16008.1 - 0.69 8.7 3.9 0.97 8.2 3.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Menin PF05053.13 EGG16008.1 - 0.92 7.8 7.5 1.1 7.5 7.5 1.2 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 EGG16008.1 - 4 6.1 5.0 3.7 6.2 5.0 1.2 1 0 0 1 1 1 0 Presenilin ATP-synt_J PF04911.12 EGG16009.1 - 0.0058 16.2 0.3 0.52 9.9 0.1 2.8 2 0 0 2 2 2 2 ATP synthase j chain EGF_2 PF07974.13 EGG16010.1 - 0.00011 22.5 11.3 0.00035 20.9 11.3 1.9 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 EGG16010.1 - 0.0027 17.9 4.3 0.0071 16.6 4.3 1.6 1 0 0 1 1 1 1 EB module LRR19-TM PF15176.6 EGG16010.1 - 0.0068 16.4 0.1 0.026 14.5 0.0 2.0 2 0 0 2 2 1 1 Leucine-rich repeat family 19 TM domain LRR_8 PF13855.6 EGG16010.1 - 0.02 14.7 22.3 1.7 8.4 3.5 6.7 5 1 1 6 6 6 0 Leucine rich repeat I-EGF_1 PF18372.1 EGG16010.1 - 0.051 13.7 10.5 0.12 12.5 10.5 1.6 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 EGG16010.1 - 0.084 13.2 7.4 0.22 11.9 7.4 1.7 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGG16010.1 - 0.1 13.3 10.8 0.29 11.8 10.8 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF LRR_9 PF14580.6 EGG16010.1 - 0.14 11.7 4.3 0.56 9.7 0.4 3.3 3 0 0 3 3 3 0 Leucine-rich repeat LRR_4 PF12799.7 EGG16010.1 - 0.63 10.6 50.1 0.14 12.6 1.9 10.1 11 1 2 13 13 10 0 Leucine Rich repeats (2 copies) DUF3844 PF12955.7 EGG16010.1 - 1.3 9.2 10.1 0.043 14.0 1.8 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF3844) EGF_Tenascin PF18720.1 EGG16010.1 - 1.6 8.8 9.6 4.4 7.5 9.6 1.8 1 0 0 1 1 1 0 Tenascin EGF domain LRR_6 PF13516.6 EGG16010.1 - 3.8 7.8 6.2 5.9 7.2 0.2 4.4 5 0 0 5 5 5 0 Leucine Rich repeat BORCS8 PF10167.9 EGG16011.1 - 7.9e-36 122.4 6.0 7.9e-36 122.4 6.0 3.0 2 2 1 3 3 3 1 BLOC-1-related complex sub-unit 8 RPW8 PF05659.11 EGG16011.1 - 0.065 12.9 0.4 0.065 12.9 0.4 1.8 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Nre_C PF04895.12 EGG16011.1 - 0.11 12.5 1.2 0.34 10.9 0.0 2.5 2 0 0 2 2 2 0 Archaeal Nre, C-terminal EGF_2 PF07974.13 EGG16012.1 - 0.007 16.7 12.0 0.007 16.7 12.0 1.8 2 0 0 2 2 2 1 EGF-like domain Toxin_11 PF07473.11 EGG16012.1 - 1.6 8.8 5.8 3 8.0 5.8 1.5 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species NPV_P10 PF05531.12 EGG16013.1 - 0.09 13.3 3.6 0.12 12.9 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.21 EGG16013.1 - 0.098 12.5 7.5 0.031 14.1 4.2 1.7 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Dynamitin PF04912.14 EGG16013.1 - 0.13 11.6 0.7 0.23 10.8 0.7 1.3 1 0 0 1 1 1 0 Dynamitin V-SNARE_C PF12352.8 EGG16013.1 - 0.15 12.4 3.0 3.3 8.1 0.2 3.0 2 2 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus MscS_porin PF12795.7 EGG16013.1 - 0.16 11.5 9.9 0.17 11.4 3.1 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain 2-Hacid_dh_C PF02826.19 EGG16014.1 - 2.4e-60 203.0 0.0 3.4e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGG16014.1 - 3.3e-26 91.5 0.1 4.1e-26 91.2 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGG16014.1 - 2.9e-07 30.8 0.1 6.1e-06 26.5 0.0 2.6 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGG16014.1 - 1.9e-05 25.1 0.0 4.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 EGG16014.1 - 8.4e-05 22.7 0.6 0.00035 20.7 0.1 2.2 2 1 1 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGG16014.1 - 0.00043 20.6 0.0 0.0018 18.5 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Gp_dh_N PF00044.24 EGG16014.1 - 0.00082 19.7 0.6 0.013 15.8 0.1 2.7 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain IlvN PF07991.12 EGG16014.1 - 0.0024 17.5 0.0 0.005 16.4 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain PRIMA1 PF16101.5 EGG16015.1 - 1.8 8.6 8.1 0.38 10.8 2.6 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SelP_N PF04592.14 EGG16015.1 - 3 7.2 12.7 0.4 10.1 8.0 1.8 2 0 0 2 2 2 0 Selenoprotein P, N terminal region ABC2_membrane PF01061.24 EGG16016.1 - 1.8e-41 141.9 15.8 1.8e-41 141.9 15.8 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGG16016.1 - 7.6e-28 97.7 0.6 7e-27 94.6 0.1 2.2 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 EGG16016.1 - 0.00021 21.0 0.1 0.00047 19.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG16016.1 - 0.00036 21.0 0.0 0.00056 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EGG16016.1 - 0.00063 19.2 0.4 0.0055 16.2 0.0 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EGG16016.1 - 0.00068 20.2 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGG16016.1 - 0.00082 19.7 0.0 0.019 15.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGG16016.1 - 0.0019 18.1 0.5 0.0046 16.9 0.5 1.6 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 EGG16016.1 - 0.0049 16.8 0.0 0.0049 16.8 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 EGG16016.1 - 0.0074 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG16016.1 - 0.0088 16.2 0.1 0.02 15.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain SRP14 PF02290.15 EGG16016.1 - 0.074 13.4 0.1 0.41 11.0 0.1 2.1 2 0 0 2 2 2 0 Signal recognition particle 14kD protein AAA_21 PF13304.6 EGG16016.1 - 0.078 12.8 0.1 0.078 12.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Cytidylate_kin PF02224.18 EGG16016.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 EGG16016.1 - 0.15 12.3 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain NIR_SIR PF01077.22 EGG16016.1 - 0.16 11.5 0.0 0.31 10.5 0.0 1.5 1 1 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain ATPase_2 PF01637.18 EGG16016.1 - 0.48 10.3 2.3 0.58 10.0 0.1 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 EGG16016.1 - 0.79 10.2 5.1 0.64 10.5 0.1 2.4 1 1 1 2 2 2 0 AAA domain SKG6 PF08693.10 EGG16017.1 - 0.015 14.6 4.1 0.054 12.9 4.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EGF_2 PF07974.13 EGG16017.1 - 0.051 13.9 7.6 0.11 12.8 7.6 1.6 1 0 0 1 1 1 0 EGF-like domain TMEM18 PF14770.6 EGG16017.1 - 0.32 11.0 2.6 0.48 10.4 0.2 2.5 2 0 0 2 2 2 0 Transmembrane protein 18 TIG PF01833.24 EGG16017.1 - 5.8 7.1 14.1 0.17 12.0 1.5 4.1 4 0 0 4 4 4 0 IPT/TIG domain Sel1 PF08238.12 EGG16018.1 - 7e-49 163.2 69.0 4.9e-05 23.9 0.3 22.3 24 1 0 24 24 24 12 Sel1 repeat TPR_7 PF13176.6 EGG16018.1 - 0.002 18.0 13.3 6.9 6.9 0.0 9.4 10 1 0 10 10 10 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG16018.1 - 0.0086 16.3 23.6 0.68 10.3 1.5 10.2 10 2 2 12 12 12 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG16018.1 - 0.28 11.6 10.3 2.9 8.5 0.2 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG16018.1 - 0.3 11.8 0.0 0.3 11.8 0.0 11.0 13 0 0 13 13 13 0 Tetratricopeptide repeat EIIBC-GUT_N PF03612.14 EGG16018.1 - 1.5 8.5 29.1 0.21 11.3 13.7 2.7 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DDRGK PF09756.9 EGG16018.1 - 3 7.4 45.8 5.6 6.5 15.3 2.7 2 0 0 2 2 2 0 DDRGK domain TPR_16 PF13432.6 EGG16018.1 - 4.9 7.9 21.7 11 6.8 0.1 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat Rad10 PF03834.14 EGG16019.1 - 0.33 11.0 3.3 0.1 12.6 0.7 1.5 2 0 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Endotoxin_N PF03945.14 EGG16020.1 - 0.0017 18.2 0.4 0.11 12.1 0.3 2.9 2 1 0 2 2 2 1 delta endotoxin, N-terminal domain SurA_N_3 PF13624.6 EGG16020.1 - 0.066 13.0 3.6 0.047 13.5 0.5 2.3 2 1 0 2 2 2 0 SurA N-terminal domain DUF2680 PF10925.8 EGG16020.1 - 8.1 6.5 8.7 1.3 9.1 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) TIG PF01833.24 EGG16021.1 - 8.6e-06 25.8 1.7 8.6e-06 25.8 1.7 6.0 3 2 3 6 6 6 2 IPT/TIG domain EGF_2 PF07974.13 EGG16021.1 - 0.099 13.0 26.5 1.5 9.3 9.0 2.6 2 0 0 2 2 2 0 EGF-like domain LapA_dom PF06305.11 EGG16021.1 - 1.3 8.9 3.2 15 5.5 0.1 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF1365 PF07103.11 EGG16022.1 - 7.9e-62 209.0 3.0 1.3e-61 208.3 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Pro-kuma_activ PF09286.11 EGG16022.1 - 3.2e-27 95.6 0.5 3e-26 92.4 0.1 2.4 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGG16022.1 - 0.00034 20.0 0.2 0.00089 18.6 0.2 1.7 1 0 0 1 1 1 1 Subtilase family Methyltransf_12 PF08242.12 EGG16022.1 - 9.8 7.0 7.1 1.5e+02 3.2 0.1 4.0 4 0 0 4 4 4 0 Methyltransferase domain SNARE_assoc PF09335.11 EGG16023.1 - 4.5e-18 65.9 8.7 4.5e-18 65.9 8.7 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF5305 PF17231.2 EGG16023.1 - 0.045 13.1 0.1 0.094 12.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SR-25 PF10500.9 EGG16023.1 - 1.3 8.6 15.7 1.6 8.2 15.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RasGEF PF00617.19 EGG16024.1 - 2.7e-38 131.9 2.4 3.1e-38 131.7 0.5 2.2 2 0 0 2 2 2 1 RasGEF domain LRR_8 PF13855.6 EGG16024.1 - 1.6e-23 82.2 31.2 1.1e-07 31.5 4.4 5.5 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 EGG16024.1 - 1.6e-16 60.1 35.9 0.00016 21.9 1.4 7.4 3 2 2 6 6 6 5 Leucine Rich repeats (2 copies) RasGEF_N PF00618.20 EGG16024.1 - 3.7e-11 43.2 0.5 3.7e-11 43.2 0.5 4.3 5 0 0 5 5 5 1 RasGEF N-terminal motif LRR_9 PF14580.6 EGG16024.1 - 7.1e-05 22.4 15.1 0.03 13.8 3.7 4.0 2 2 2 4 4 4 4 Leucine-rich repeat DUF4937 PF16291.5 EGG16024.1 - 0.13 12.5 0.7 0.32 11.3 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 7tm_2 PF00002.24 EGG16026.1 - 2.9e-06 26.8 0.1 0.00014 21.3 0.0 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 EGG16026.1 - 2.3e-05 23.9 0.0 3.8e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.17 EGG16026.1 - 0.0027 16.8 2.1 0.0053 15.8 0.3 2.0 2 0 0 2 2 2 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.11 EGG16026.1 - 0.0036 16.5 0.5 0.0036 16.5 0.5 3.1 3 1 0 3 3 3 1 Slime mold cyclic AMP receptor VIT1 PF01988.19 EGG16026.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 VIT family ABC2_membrane_3 PF12698.7 EGG16026.1 - 0.014 14.5 5.3 0.027 13.6 5.3 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Macoilin PF09726.9 EGG16026.1 - 0.64 8.5 5.5 0.82 8.1 5.5 1.1 1 0 0 1 1 1 0 Macoilin family AI-2E_transport PF01594.16 EGG16026.1 - 1 8.5 9.0 0.95 8.5 2.1 2.4 2 1 0 2 2 2 0 AI-2E family transporter GPR_Gpa2_C PF11970.8 EGG16026.1 - 1 9.5 6.6 0.24 11.5 3.0 1.9 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Menin PF05053.13 EGG16026.1 - 1.2 7.4 5.3 1.7 6.9 5.3 1.1 1 0 0 1 1 1 0 Menin Acetyltransf_9 PF13527.7 EGG16027.1 - 1.3e-05 25.3 0.0 3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG16027.1 - 4.6e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 EGG16027.1 - 0.025 14.0 0.2 0.039 13.4 0.2 1.4 1 0 0 1 1 1 0 Putative acetyl-transferase Ank_2 PF12796.7 EGG16029.1 - 0.00012 22.6 0.1 0.00028 21.4 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DUF5049 PF16468.5 EGG16029.1 - 0.016 15.1 0.1 0.033 14.1 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5049) Ank_4 PF13637.6 EGG16029.1 - 0.03 14.9 0.1 0.79 10.4 0.0 2.9 2 1 0 2 2 2 0 Ankyrin repeats (many copies) ABC_membrane_3 PF13748.6 EGG16029.1 - 0.043 13.1 0.3 0.062 12.5 0.3 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region Ank_5 PF13857.6 EGG16029.1 - 0.59 10.5 4.4 0.73 10.2 0.0 3.0 2 1 2 4 4 4 0 Ankyrin repeats (many copies) DUF3430 PF11912.8 EGG16030.1 - 2.7e-14 53.7 38.5 3.8e-14 53.3 38.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Argos PF11581.8 EGG16030.1 - 0.0029 17.6 0.2 0.33 11.0 0.2 2.3 2 0 0 2 2 2 2 Antagonist of EGFR signalling, Argos EGF_2 PF07974.13 EGG16031.1 - 6.5e-05 23.2 15.3 0.00014 22.1 15.3 1.6 1 0 0 1 1 1 1 EGF-like domain DUF3844 PF12955.7 EGG16031.1 - 0.00028 21.0 3.6 0.00063 19.8 0.9 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) EB PF01683.18 EGG16031.1 - 0.0019 18.5 3.7 0.0037 17.5 3.7 1.5 1 0 0 1 1 1 1 EB module I-EGF_1 PF18372.1 EGG16031.1 - 0.0053 16.8 8.3 0.011 15.8 8.3 1.5 1 0 0 1 1 1 1 Integrin beta epidermal growth factor like domain 1 hEGF PF12661.7 EGG16031.1 - 0.12 13.1 14.8 0.037 14.7 10.9 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 EGG16031.1 - 1.3 9.1 6.9 3.4 7.8 6.9 1.7 1 0 0 1 1 1 0 Tenascin EGF domain EGF PF00008.27 EGG16031.1 - 2.8 8.3 14.3 0.77 10.1 9.9 2.3 2 0 0 2 2 2 0 EGF-like domain LRR_1 PF00560.33 EGG16031.1 - 4 8.4 4.8 1.7e+02 3.4 0.1 5.2 4 0 0 4 4 4 0 Leucine Rich Repeat ketoacyl-synt PF00109.26 EGG16032.1 - 2.9e-58 197.4 0.8 6.1e-58 196.4 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG16032.1 - 3.3e-48 164.8 0.1 6.4e-48 163.9 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGG16032.1 - 1.4e-36 125.1 0.0 8.9e-35 119.3 0.1 3.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGG16032.1 - 1.6e-28 99.8 0.4 7e-28 97.8 0.0 2.4 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGG16032.1 - 6.8e-20 71.5 0.0 1.2e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGG16032.1 - 9.4e-16 58.3 2.5 2.1e-15 57.2 0.0 2.8 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGG16032.1 - 8.7e-10 39.8 0.0 5.8e-07 30.6 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGG16032.1 - 1.7e-07 31.3 0.0 1.4e-06 28.3 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EGG16032.1 - 4.2e-07 30.2 0.0 1.1e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EGG16032.1 - 4.4e-05 23.3 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGG16032.1 - 0.0002 20.8 1.0 0.0015 18.0 1.0 2.3 1 1 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 EGG16032.1 - 0.031 13.8 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase LRR_8 PF13855.6 EGG16033.1 - 0.0039 16.9 0.2 0.013 15.2 0.2 1.8 1 0 0 1 1 1 1 Leucine rich repeat TIG PF01833.24 EGG16034.1 - 0.00073 19.6 3.5 0.0041 17.2 3.0 2.7 2 0 0 2 2 2 1 IPT/TIG domain EGF_2 PF07974.13 EGG16034.1 - 0.0015 18.9 11.5 0.0038 17.6 11.5 1.7 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 EGG16034.1 - 0.0033 17.7 3.2 0.0084 16.4 3.2 1.7 1 0 0 1 1 1 1 EB module hEGF PF12661.7 EGG16034.1 - 0.83 10.4 11.2 2.9 8.6 11.2 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF 7tm_3 PF00003.22 EGG16035.1 - 7.1e-44 150.3 19.7 1.4e-43 149.4 19.7 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 EGG16035.1 - 2.7e-06 26.6 0.6 4.4e-06 25.9 0.6 1.2 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like DUF2157 PF09925.9 EGG16035.1 - 2 8.2 8.2 0.44 10.3 1.7 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) CSN5_C PF18323.1 EGG16036.1 - 0.11 13.5 1.1 0.17 12.8 1.1 1.3 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain NUC173 PF08161.12 EGG16037.1 - 3.1e-54 183.7 0.2 3.1e-54 183.7 0.2 3.2 4 0 0 4 4 4 1 NUC173 domain EF-G-binding_N PF07299.11 EGG16037.1 - 0.054 14.0 0.3 0.45 11.1 0.3 2.8 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal GEMIN8 PF15348.6 EGG16037.1 - 3.7 7.8 10.2 0.18 12.1 2.1 2.5 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 LRR_8 PF13855.6 EGG16038.1 - 0.02 14.7 9.2 0.081 12.7 0.1 3.9 5 0 0 5 5 5 0 Leucine rich repeat RabGAP-TBC PF00566.18 EGG16039.1 - 9.2e-32 110.4 0.3 9.2e-32 110.4 0.3 2.7 2 1 1 3 3 3 1 Rab-GTPase-TBC domain TLD PF07534.16 EGG16039.1 - 1.9e-24 86.5 0.2 1.9e-24 86.5 0.2 1.9 2 0 0 2 2 2 1 TLD YajC PF02699.15 EGG16039.1 - 8.2 6.4 5.9 18 5.3 5.9 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit HSP90 PF00183.18 EGG16040.1 - 0.018 14.0 2.2 0.019 13.9 2.2 1.0 1 0 0 1 1 1 0 Hsp90 protein Eapp_C PF10238.9 EGG16040.1 - 0.04 14.0 1.2 0.038 14.1 1.2 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein PseudoU_synth_2 PF00849.22 EGG16041.1 - 3.6e-20 72.6 3.2 3.6e-20 72.6 3.2 2.8 2 1 0 2 2 2 1 RNA pseudouridylate synthase SNF2_N PF00176.23 EGG16042.1 - 9.7e-61 205.4 0.6 9.7e-61 205.4 0.6 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG16042.1 - 2.5e-18 66.4 0.0 7.6e-18 64.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 EGG16042.1 - 7.1e-17 61.1 2.7 7.5e-10 38.6 0.1 3.7 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1086 PF06461.11 EGG16042.1 - 0.039 13.8 0.1 7.2 6.5 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1086) AT_hook PF02178.19 EGG16042.1 - 0.39 10.7 6.2 1.1 9.3 6.2 1.9 1 0 0 1 1 1 0 AT hook motif Docking PF08990.11 EGG16045.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Erythronolide synthase docking Pkinase_Tyr PF07714.17 EGG16047.1 - 3.7e-62 210.0 0.1 9.7e-62 208.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGG16047.1 - 1.2e-50 172.4 0.0 2.7e-50 171.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 EGG16047.1 - 3e-35 121.8 0.0 3e-35 121.8 0.0 2.2 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 EGG16047.1 - 9.4e-08 32.3 0.0 1.8e-06 28.2 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase WD40_like PF17005.5 EGG16047.1 - 8e-06 25.4 2.0 2.5e-05 23.8 2.0 1.8 1 0 0 1 1 1 1 WD40-like domain WD40 PF00400.32 EGG16047.1 - 0.022 15.6 0.3 0.28 12.1 0.0 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat MecA PF05389.12 EGG16047.1 - 0.066 12.8 5.2 2.5 7.6 1.1 2.9 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF4770 PF15994.5 EGG16047.1 - 0.24 11.6 10.0 2.1 8.6 2.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) EPL1 PF10513.9 EGG16047.1 - 0.36 11.2 20.5 2.1 8.7 0.4 4.4 4 0 0 4 4 4 0 Enhancer of polycomb-like Tim54 PF11711.8 EGG16047.1 - 5.2 5.7 6.2 13 4.4 2.0 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 PTS_2-RNA PF01885.16 EGG16048.1 - 2.5e-66 223.2 0.7 2.9e-66 223.0 0.7 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Ank_2 PF12796.7 EGG16049.1 - 1.6e-24 86.3 16.1 3.3e-09 37.2 0.1 7.7 5 3 2 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16049.1 - 2.2e-19 69.6 9.5 0.0002 21.8 0.0 7.6 8 1 0 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 EGG16049.1 - 7e-17 61.0 16.1 0.0027 18.1 0.0 9.7 9 2 1 10 10 10 4 Ankyrin repeat Ank_3 PF13606.6 EGG16049.1 - 2.4e-14 52.0 11.3 0.00032 20.9 0.1 8.4 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 EGG16049.1 - 1.6e-10 41.0 18.2 0.037 14.4 0.1 7.7 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Anti-adapt_IraP PF10796.9 EGG16049.1 - 5.2 7.7 6.6 12 6.6 0.0 4.0 4 0 0 4 4 4 0 Sigma-S stabilisation anti-adaptor protein Ank_2 PF12796.7 EGG16051.1 - 3.7e-06 27.4 0.7 0.069 13.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16051.1 - 5.3e-06 26.9 0.7 0.0079 16.8 0.1 4.6 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16051.1 - 3.8e-05 23.7 0.2 3.5 8.5 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EGG16051.1 - 0.0034 17.6 0.0 0.35 11.2 0.0 3.9 3 1 1 4 4 4 1 Ankyrin repeats (many copies) TIG PF01833.24 EGG16052.1 - 8.7e-66 218.0 92.7 2.7e-13 49.8 0.1 14.4 15 0 0 15 15 15 11 IPT/TIG domain DNase_II PF03265.15 EGG16052.1 - 7e-14 51.8 1.1 2.6e-13 50.0 1.1 2.0 1 0 0 1 1 1 1 Deoxyribonuclease II SdrD_B PF17210.3 EGG16052.1 - 2e-10 40.9 3.6 2.7e-06 27.6 0.3 7.9 9 0 0 9 9 9 5 SdrD B-like domain DiSB-ORF2_chro PF16506.5 EGG16052.1 - 0.1 12.6 0.4 0.81 9.7 0.1 2.8 2 0 0 2 2 2 0 Putative virion glycoprotein of insect viruses Mito_fiss_reg PF05308.11 EGG16052.1 - 8 6.5 12.1 21 5.1 12.1 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator TIG PF01833.24 EGG16053.1 - 1e-12 47.9 2.2 1.5e-09 37.8 0.1 3.0 3 0 0 3 3 3 2 IPT/TIG domain Choline_kin_N PF04428.14 EGG16054.1 - 0.19 11.5 0.1 0.37 10.5 0.1 1.5 1 0 0 1 1 1 0 Choline kinase N terminus TIG PF01833.24 EGG16055.1 - 3e-30 104.1 44.8 1.6e-09 37.7 0.9 9.9 8 1 1 9 9 9 6 IPT/TIG domain DNase_II PF03265.15 EGG16055.1 - 1.4e-20 73.9 14.5 3.5e-12 46.2 0.8 3.6 2 1 1 3 3 3 3 Deoxyribonuclease II PRKCSH_1 PF13015.6 EGG16055.1 - 1.5e-19 70.2 7.7 1.4e-05 24.8 0.3 3.6 3 0 0 3 3 3 3 Glucosidase II beta subunit-like protein Ank_2 PF12796.7 EGG16056.1 - 7.5e-06 26.4 0.0 0.22 12.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG16056.1 - 0.048 14.2 0.0 20 6.2 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 EGG16057.1 - 0.019 15.5 0.0 1.6 9.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 EGG16058.1 - 5.2e-08 33.4 0.3 0.18 12.4 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16058.1 - 0.0062 17.1 0.2 1e+02 3.6 0.0 5.0 4 1 2 6 6 6 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16058.1 - 0.012 16.1 0.1 28 5.7 0.0 5.0 6 0 0 6 6 6 0 Ankyrin repeat WD40 PF00400.32 EGG16059.1 - 1.2e-39 133.5 22.2 1.8e-07 31.7 0.1 11.4 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG16059.1 - 1.5e-16 60.4 1.3 0.0015 18.8 0.0 6.0 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGG16059.1 - 0.00037 20.3 0.2 21 5.2 0.0 4.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EGG16059.1 - 0.00097 18.5 0.3 3.1 7.0 0.0 3.5 3 1 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 EGG16059.1 - 0.011 14.4 1.2 0.13 10.9 0.5 2.7 2 1 0 3 3 3 0 Nucleoporin Nup120/160 WDCP PF15390.6 EGG16059.1 - 0.042 12.2 0.5 0.12 10.7 0.1 1.8 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family Me-amine-dh_H PF06433.11 EGG16059.1 - 0.054 12.3 0.0 0.48 9.2 0.0 2.4 3 0 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) Nucleoporin_N PF08801.11 EGG16059.1 - 0.065 12.0 2.7 0.11 11.2 0.1 2.6 3 1 1 4 4 4 0 Nup133 N terminal like Ge1_WD40 PF16529.5 EGG16059.1 - 0.83 8.6 4.8 13 4.6 0.5 4.3 3 2 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ETF_QO PF05187.13 EGG16061.1 - 8.4e-48 160.8 0.2 2.6e-47 159.2 0.2 1.9 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S IPK PF03770.16 EGG16061.1 - 2.2e-41 141.9 0.5 1.6e-40 139.1 0.5 2.3 1 1 0 1 1 1 1 Inositol polyphosphate kinase FAD_binding_2 PF00890.24 EGG16061.1 - 1.7e-07 30.7 0.4 2.2e-05 23.7 1.2 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EGG16061.1 - 3.6e-06 26.8 0.6 0.0017 18.0 0.7 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGG16061.1 - 8.8e-06 25.9 0.6 6e-05 23.2 0.0 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGG16061.1 - 9.7e-06 25.0 0.0 2.9e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EGG16061.1 - 0.00036 19.9 0.0 0.00064 19.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG16061.1 - 0.00041 20.4 0.1 0.0013 18.7 0.1 1.9 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EGG16061.1 - 0.00049 18.9 0.3 0.00049 18.9 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EGG16061.1 - 0.0013 17.9 0.2 0.002 17.2 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EGG16061.1 - 0.0073 15.6 0.1 0.017 14.4 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EGG16061.1 - 0.009 15.3 0.3 0.022 14.0 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGG16061.1 - 0.012 14.7 0.1 0.045 12.9 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_7 PF12838.7 EGG16061.1 - 0.018 15.6 0.9 0.049 14.2 0.9 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pyr_redox PF00070.27 EGG16061.1 - 0.032 14.8 0.2 14 6.3 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGG16061.1 - 0.038 13.3 1.6 0.042 13.2 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGG16061.1 - 0.055 12.3 0.1 0.68 8.7 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Methyltransf_11 PF08241.12 EGG16062.1 - 3.7e-18 65.9 0.0 5.3e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG16062.1 - 3.2e-16 59.8 0.0 4.5e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG16062.1 - 4.9e-12 46.0 0.0 7.4e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG16062.1 - 7.3e-11 42.1 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG16062.1 - 7.6e-10 39.4 0.0 1.2e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG16062.1 - 6.5e-06 25.7 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGG16062.1 - 0.00013 21.6 0.0 0.00026 20.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 EGG16062.1 - 0.00064 19.6 0.0 0.0019 18.1 0.0 1.7 2 1 0 2 2 2 1 Hypothetical methyltransferase NodS PF05401.11 EGG16062.1 - 0.001 18.7 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 EGG16062.1 - 0.019 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.19 EGG16062.1 - 0.04 14.0 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Peptidase_M99 PF17033.5 EGG16062.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Carboxypeptidase controlling helical cell shape catalytic Citrate_synt PF00285.21 EGG16063.1 - 1.3e-23 83.7 0.0 3e-19 69.3 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 EGG16063.1 - 4.6e-11 42.8 0.0 9.1e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EGG16063.1 - 1.2e-05 25.1 0.0 9.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain NLPC_P60 PF00877.19 EGG16064.1 - 3.3e-10 39.9 0.2 0.00027 20.9 1.1 2.5 2 0 0 2 2 2 2 NlpC/P60 family Presenilin PF01080.17 EGG16064.1 - 0.79 8.4 5.6 1.1 8.0 5.6 1.2 1 0 0 1 1 1 0 Presenilin Glyco_hydro_71 PF03659.14 EGG16065.1 - 0.009 14.9 0.1 0.011 14.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 RICTOR_phospho PF14665.6 EGG16066.1 - 0.016 15.5 0.1 0.028 14.7 0.1 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site AT_hook PF02178.19 EGG16067.1 - 0.068 13.1 0.5 0.18 11.8 0.5 1.8 1 0 0 1 1 1 0 AT hook motif UvrA_inter PF17760.1 EGG16067.1 - 0.22 11.6 1.6 1.3 9.1 0.3 2.7 2 0 0 2 2 2 0 UvrA interaction domain Macoilin PF09726.9 EGG16067.1 - 2.4 6.6 10.5 3.7 6.0 1.2 2.3 2 0 0 2 2 2 0 Macoilin family OrfB_Zn_ribbon PF07282.11 EGG16068.1 - 9.1e-06 25.5 0.0 0.0063 16.4 0.0 3.2 2 0 0 2 2 2 2 Putative transposase DNA-binding domain DUF2992 PF11208.8 EGG16068.1 - 0.028 14.6 0.0 0.028 14.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Rho_N PF07498.12 EGG16068.1 - 1.8 8.5 5.0 5.2 7.1 0.2 3.5 4 0 0 4 4 4 0 Rho termination factor, N-terminal domain Cupin_8 PF13621.6 EGG16069.1 - 3.3e-22 79.4 0.4 5.9e-22 78.6 0.4 1.4 1 1 0 1 1 1 1 Cupin-like domain SPX PF03105.19 EGG16070.1 - 1 9.2 4.8 1.2 9.0 4.8 1.1 1 0 0 1 1 1 0 SPX domain SSP160 PF06933.11 EGG16070.1 - 9.9 4.2 10.0 15 3.6 10.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CPSF73-100_C PF11718.8 EGG16071.1 - 2.2e-60 203.9 4.2 3.9e-60 203.1 4.2 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EGG16071.1 - 3.9e-31 107.6 0.0 3.9e-31 107.6 0.0 2.3 2 1 0 2 2 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EGG16071.1 - 4.2e-21 75.3 0.2 2.2e-20 72.9 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EGG16071.1 - 4.3e-17 62.8 0.0 1.4e-16 61.1 0.0 1.7 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EGG16071.1 - 1.2e-15 57.1 0.0 3.1e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 EGG16071.1 - 5e-06 26.5 0.1 4.2e-05 23.5 0.0 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EGG16071.1 - 9.7e-06 25.2 0.5 4e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EGG16071.1 - 2.9e-05 23.4 0.0 9.3e-05 21.8 0.0 1.9 1 0 0 1 1 1 1 Putative beta-lactamase-like family Myc_N PF01056.18 EGG16071.1 - 0.0024 17.8 1.5 0.0037 17.2 1.5 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Coat_F PF07875.12 EGG16071.1 - 0.071 13.3 0.1 6.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Coat F domain SRP14 PF02290.15 EGG16071.1 - 0.32 11.4 2.1 4 7.9 0.6 2.9 2 0 0 2 2 2 0 Signal recognition particle 14kD protein DUF1604 PF07713.13 EGG16072.1 - 0.08 12.8 0.4 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) Cyclin PF08613.11 EGG16076.1 - 3.3e-06 27.6 1.6 3.3e-06 27.6 1.6 4.4 3 3 1 4 4 4 1 Cyclin PP2C_2 PF13672.6 EGG16077.1 - 0.0083 15.8 0.0 0.82 9.3 0.0 2.7 2 0 0 2 2 2 2 Protein phosphatase 2C RecA PF00154.21 EGG16078.1 - 3.5e-23 82.4 0.0 1.2e-22 80.7 0.0 1.7 2 0 0 2 2 2 1 recA bacterial DNA recombination protein Rad51 PF08423.11 EGG16078.1 - 2.7e-07 30.1 0.0 2.1e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 EGG16078.1 - 4.9e-06 26.1 0.0 4e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.6 EGG16078.1 - 0.041 14.2 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MRP-S33 PF08293.11 EGG16078.1 - 0.24 11.7 2.8 0.45 10.8 2.8 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 ADK PF00406.22 EGG16079.1 - 2.4e-10 40.7 1.4 1.1e-08 35.4 0.1 3.1 3 1 0 3 3 3 1 Adenylate kinase AAA_17 PF13207.6 EGG16079.1 - 0.00082 19.8 0.0 0.0023 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain RAP1 PF07218.11 EGG16079.1 - 0.27 9.5 17.5 0.51 8.6 17.5 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Coilin_N PF15862.5 EGG16079.1 - 0.49 10.2 10.4 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Coilin N-terminus Macoilin PF09726.9 EGG16079.1 - 2.1 6.8 12.8 2.9 6.3 12.8 1.2 1 0 0 1 1 1 0 Macoilin family Ribosomal_S3Ae PF01015.18 EGG16080.1 - 5.8e-81 270.9 6.3 7.1e-81 270.6 6.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family PepSY_like PF11396.8 EGG16080.1 - 0.096 13.2 0.6 0.25 11.9 0.6 1.8 1 0 0 1 1 1 0 Putative beta-lactamase-inhibitor-like, PepSY-like Spt20 PF12090.8 EGG16081.1 - 0.0077 15.9 7.6 0.0077 15.9 7.6 2.9 2 1 0 2 2 2 1 Spt20 family Cdh1_DBD_1 PF18196.1 EGG16081.1 - 1.2 9.4 7.9 0.078 13.3 0.7 2.3 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DUF469 PF04320.14 EGG16081.1 - 2.2 9.2 5.7 16 6.4 0.1 3.5 3 0 0 3 3 3 0 Protein with unknown function (DUF469) Adap_comp_sub PF00928.21 EGG16082.1 - 2.2e-89 299.3 0.0 2.8e-89 299.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGG16082.1 - 8.6e-09 35.5 0.7 1.5e-08 34.7 0.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain BLYB PF05289.11 EGG16082.1 - 0.35 11.1 2.5 0.86 9.8 2.5 1.7 1 1 0 1 1 1 0 Borrelia hemolysin accessory protein Sod_Fe_C PF02777.18 EGG16083.1 - 3.1e-28 97.9 0.8 9e-28 96.5 0.1 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGG16083.1 - 4.4e-12 46.3 3.3 1.2e-11 45.0 0.0 2.8 2 1 1 3 3 3 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF740 PF05340.12 EGG16083.1 - 1 8.0 4.9 1.5 7.5 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) EF-hand_like PF09279.11 EGG16084.1 - 0.016 15.6 2.3 0.026 15.0 0.3 1.9 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Ank_2 PF12796.7 EGG16085.1 - 3.6e-22 78.7 5.9 7.1e-12 45.7 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16085.1 - 4.2e-20 71.8 0.8 3e-07 30.8 0.1 5.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16085.1 - 1.2e-18 66.9 0.9 1.9e-08 34.4 0.0 4.1 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EGG16085.1 - 1.7e-17 63.0 2.7 0.0038 17.6 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EGG16085.1 - 1.5e-14 52.7 0.0 0.01 16.3 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat PALP PF00291.25 EGG16087.1 - 1.5e-85 287.1 0.2 5.1e-74 249.3 0.2 4.0 3 1 0 3 3 3 3 Pyridoxal-phosphate dependent enzyme ACT_4 PF13291.6 EGG16087.1 - 0.016 15.8 0.1 0.49 11.0 0.0 3.0 2 0 0 2 2 2 0 ACT domain EF-hand_7 PF13499.6 EGG16087.1 - 0.04 14.4 0.2 0.18 12.3 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 EGG16087.1 - 0.33 10.6 2.1 3.7 7.3 0.2 2.8 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 EGG16087.1 - 0.45 10.6 2.2 2.4 8.3 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain Ank_2 PF12796.7 EGG16089.1 - 1.1e-38 131.7 18.6 1.2e-14 54.6 0.3 5.0 2 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16089.1 - 8e-29 99.6 4.4 1.4e-05 25.5 0.1 5.6 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Coilin_N PF15862.5 EGG16089.1 - 2.7e-27 95.3 10.6 2.7e-27 95.3 10.6 4.9 6 0 0 6 6 6 1 Coilin N-terminus Ank_3 PF13606.6 EGG16089.1 - 6.2e-19 66.1 3.0 0.0012 19.1 0.1 7.6 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 EGG16089.1 - 2.3e-18 65.7 8.8 0.012 16.0 0.1 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EGG16089.1 - 1.2e-15 57.3 0.6 7.1e-06 26.2 0.2 5.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) SH2 PF00017.24 EGG16089.1 - 4e-06 26.8 0.1 2e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 SH2 domain F-box-like PF12937.7 EGG16089.1 - 4.5e-05 23.2 1.0 0.0001 22.1 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG16089.1 - 0.00021 21.0 1.3 0.0005 19.9 1.3 1.7 1 0 0 1 1 1 1 F-box domain ArfGap PF01412.18 EGG16090.1 - 3.9e-34 117.2 0.1 3.9e-34 117.2 0.1 3.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf DUF3446 PF11928.8 EGG16090.1 - 0.024 15.0 3.7 0.024 15.0 3.7 6.9 4 1 0 4 4 4 0 Early growth response N-terminal domain ROS_MUCR PF05443.11 EGG16090.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Rap_GAP PF02145.15 EGG16091.1 - 2e-63 213.3 0.1 2.9e-63 212.8 0.1 1.2 1 0 0 1 1 1 1 Rap/ran-GAP DUF4590 PF15257.6 EGG16091.1 - 0.19 11.6 0.0 1.9 8.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4590) rRNA_processing PF08524.11 EGG16092.1 - 0.0013 18.8 22.8 0.0013 18.8 22.8 2.5 1 1 1 2 2 2 1 rRNA processing DUF3439 PF11921.8 EGG16092.1 - 0.0075 16.2 2.9 0.014 15.3 2.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.17 EGG16092.1 - 0.044 13.8 12.2 0.058 13.4 12.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 EGG16092.1 - 0.25 9.5 7.6 0.29 9.3 7.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Roughex PF06020.11 EGG16092.1 - 1.1 8.3 16.1 1.3 8.0 16.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF3446 PF11928.8 EGG16093.1 - 0.28 11.5 10.1 0.81 10.0 3.0 2.7 3 0 0 3 3 3 0 Early growth response N-terminal domain NPDC1 PF06809.11 EGG16093.1 - 2 7.3 4.8 0.82 8.7 0.3 2.1 2 0 0 2 2 2 0 Neural proliferation differentiation control-1 protein (NPDC1) Ribosomal_S17_N PF16205.5 EGG16094.1 - 9.1e-30 102.9 1.1 1.9e-29 101.8 1.1 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EGG16094.1 - 1.3e-25 89.3 0.6 1.3e-25 89.3 0.6 1.5 2 0 0 2 2 2 1 Ribosomal protein S17 Strep_his_triad PF04270.13 EGG16094.1 - 0.13 12.3 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Streptococcal histidine triad protein FH2 PF02181.23 EGG16095.1 - 3e-78 263.5 15.1 9.7e-71 238.8 6.8 2.8 2 1 1 3 3 3 2 Formin Homology 2 Domain Drf_GBD PF06371.13 EGG16095.1 - 2.4e-45 154.4 4.7 2.4e-45 154.4 4.7 2.7 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGG16095.1 - 1e-22 80.7 0.4 1e-22 80.7 0.4 2.2 2 0 0 2 2 2 1 Diaphanous FH3 Domain adh_short PF00106.25 EGG16095.1 - 2.5e-10 40.2 0.2 1.3e-09 37.8 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG16095.1 - 5.5e-08 32.6 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3361 PF11841.8 EGG16095.1 - 5.7e-08 32.8 3.7 1.5e-07 31.5 3.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Epimerase PF01370.21 EGG16095.1 - 0.0046 16.5 0.0 0.011 15.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGG16095.1 - 0.093 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain SRP-alpha_N PF04086.13 EGG16095.1 - 3.6 7.4 36.6 0.87 9.5 23.8 2.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal LRR_6 PF13516.6 EGG16096.1 - 2.9e-15 54.9 16.1 0.0012 18.8 0.0 7.3 7 0 0 7 7 7 5 Leucine Rich repeat Ras PF00071.22 EGG16096.1 - 2.5e-13 49.9 0.2 2.5e-13 49.9 0.2 2.5 2 1 0 2 2 2 1 Ras family Tox-REase-3 PF15647.6 EGG16096.1 - 0.023 15.0 4.3 0.069 13.4 4.3 1.9 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 LRR_4 PF12799.7 EGG16096.1 - 0.059 13.8 11.9 1.3 9.6 0.8 4.1 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Asp-B-Hydro_N PF05279.11 EGG16096.1 - 0.093 12.8 17.0 0.15 12.1 17.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3552 PF12072.8 EGG16096.1 - 0.53 9.7 22.7 0.94 8.9 22.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) STN1_2 PF09170.10 EGG16096.1 - 9.1 6.5 15.8 17 5.5 0.0 2.3 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Presenilin PF01080.17 EGG16096.1 - 9.2 4.9 11.3 14 4.3 11.3 1.2 1 0 0 1 1 1 0 Presenilin NUDIX PF00293.28 EGG16097.1 - 6.6e-09 35.9 0.0 2e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain EGF_2 PF07974.13 EGG16097.1 - 0.0015 18.8 11.7 0.0015 18.8 11.7 3.8 3 0 0 3 3 3 1 EGF-like domain PHP PF02811.19 EGG16097.1 - 0.021 15.1 0.0 0.084 13.2 0.0 1.9 2 0 0 2 2 2 0 PHP domain Patatin PF01734.22 EGG16097.1 - 0.11 12.6 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Patatin-like phospholipase CMAS PF02353.20 EGG16099.1 - 6.2e-93 311.0 0.2 9.7e-93 310.4 0.2 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGG16099.1 - 2.5e-13 50.6 0.0 7.3e-13 49.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG16099.1 - 4.1e-11 43.4 0.0 9.5e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG16099.1 - 8.1e-11 42.0 0.0 2.8e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG16099.1 - 2.6e-08 33.8 0.1 5.9e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG16099.1 - 4.5e-08 33.8 0.1 5.7e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 EGG16099.1 - 0.00017 21.8 0.0 0.00093 19.4 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 EGG16099.1 - 0.0024 17.5 0.0 0.0051 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 EGG16099.1 - 0.0033 17.0 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 ADH_zinc_N PF00107.26 EGG16099.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MetW PF07021.12 EGG16099.1 - 0.019 14.6 0.1 0.051 13.2 0.1 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PCMT PF01135.19 EGG16099.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EGG16099.1 - 0.062 13.3 2.2 0.079 13.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain LMBR1 PF04791.16 EGG16099.1 - 0.23 10.3 0.7 0.32 9.8 0.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein NST1 PF13945.6 EGG16099.1 - 3 7.9 8.2 5.2 7.1 8.2 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator MAP65_ASE1 PF03999.12 EGG16099.1 - 3.6 6.2 8.5 4.7 5.8 8.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ketoacyl-synt PF00109.26 EGG16100.1 - 5.8e-58 196.4 0.6 1.4e-57 195.2 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG16100.1 - 2.7e-47 161.9 0.0 4.9e-47 161.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGG16100.1 - 2.7e-36 124.1 0.0 9.1e-35 119.2 0.1 3.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGG16100.1 - 4.1e-27 95.3 0.3 1.3e-26 93.6 0.0 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGG16100.1 - 3e-20 72.7 0.0 5.1e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGG16100.1 - 1.7e-16 60.6 0.5 9e-16 58.3 0.0 2.5 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGG16100.1 - 6.9e-08 33.6 0.0 2.7e-06 28.5 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EGG16100.1 - 3.8e-07 30.4 0.0 1e-06 29.0 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 EGG16100.1 - 1.7e-06 28.0 0.0 7.1e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG16100.1 - 4.6e-05 23.3 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGG16100.1 - 0.00044 19.7 1.1 0.0024 17.3 1.1 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Lyase_aromatic PF00221.19 EGG16101.1 - 3.1e-192 639.3 0.1 3.6e-192 639.2 0.1 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase TMPIT PF07851.13 EGG16102.1 - 4.1e-108 361.5 9.4 4.8e-108 361.3 9.4 1.0 1 0 0 1 1 1 1 TMPIT-like protein SOAR PF16533.5 EGG16102.1 - 0.17 11.9 4.3 0.65 10.0 4.3 1.9 1 1 0 1 1 1 0 STIM1 Orai1-activating region PHM7_cyt PF14703.6 EGG16102.1 - 0.25 11.6 2.6 0.74 10.0 2.6 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter UPF0242 PF06785.11 EGG16102.1 - 8.4 6.4 10.7 21 5.2 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Gtr1_RagA PF04670.12 EGG16103.1 - 3.6e-103 343.9 1.9 4.8e-103 343.5 1.9 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EGG16103.1 - 1.1e-09 38.6 0.4 5.2e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG16103.1 - 4.5e-09 36.1 0.1 8.4e-09 35.2 0.1 1.7 1 1 0 1 1 1 1 Ras family Arf PF00025.21 EGG16103.1 - 1.8e-08 34.1 0.1 3e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG16103.1 - 1.3e-07 31.6 0.0 3.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGG16103.1 - 0.0078 15.7 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Spectrin_like PF18373.1 EGG16103.1 - 0.078 13.1 1.1 0.87 9.7 0.1 2.9 3 0 0 3 3 3 0 Spectrin like domain zf-C5HC2 PF02928.16 EGG16103.1 - 0.16 12.4 0.6 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 C5HC2 zinc finger Macro PF01661.21 EGG16105.1 - 4.4e-31 107.4 0.1 2.2e-30 105.1 0.1 2.2 2 0 0 2 2 2 1 Macro domain WWE PF02825.20 EGG16105.1 - 1.2e-25 89.9 27.2 4.7e-10 39.9 0.0 4.1 4 0 0 4 4 4 3 WWE domain NDUFA12 PF05071.16 EGG16106.1 - 2.9e-28 98.5 1.6 3.7e-28 98.2 1.6 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TPR_2 PF07719.17 EGG16107.1 - 3.7e-09 36.0 6.0 0.012 15.7 0.0 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG16107.1 - 6.4e-08 32.2 3.4 0.31 11.4 0.1 5.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG16107.1 - 7.4e-06 25.6 0.8 0.021 14.8 0.2 4.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG16107.1 - 0.00015 22.0 7.1 0.71 10.2 0.1 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG16107.1 - 0.00084 19.1 12.2 0.12 12.3 0.3 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG16107.1 - 0.0033 17.7 0.2 67 4.2 0.0 5.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGG16107.1 - 0.0053 16.9 0.1 0.013 15.6 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat THOC7 PF05615.13 EGG16107.1 - 0.0068 16.7 0.7 0.031 14.6 0.7 2.2 1 0 0 1 1 1 1 Tho complex subunit 7 DUF1475 PF07343.11 EGG16107.1 - 0.098 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) DUF1664 PF07889.12 EGG16107.1 - 0.12 12.5 1.5 0.49 10.4 1.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TPR_10 PF13374.6 EGG16107.1 - 0.18 11.7 0.3 41 4.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.6 EGG16107.1 - 0.24 11.9 7.3 1.4 9.4 5.6 3.2 2 0 0 2 2 2 0 Snapin/Pallidin DUF4094 PF13334.6 EGG16107.1 - 0.42 11.0 4.2 1.8 9.0 2.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Lung_7-TM_R PF06814.13 EGG16108.1 - 3e-05 23.4 1.3 3e-05 23.4 1.3 2.6 3 0 0 3 3 3 2 Lung seven transmembrane receptor Spermine_synth PF01564.17 EGG16109.1 - 3.4e-68 228.8 0.0 1.4e-67 226.8 0.0 1.9 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EGG16109.1 - 1.1e-23 82.9 0.3 1.8e-23 82.2 0.3 1.3 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EGG16109.1 - 0.00026 21.7 0.0 0.00056 20.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGG16109.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGG16109.1 - 0.086 13.6 0.0 0.18 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Autophagy_act_C PF03987.15 EGG16110.1 - 3e-07 30.9 0.1 4.6e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_act_C PF03987.15 EGG16111.1 - 0.00011 22.7 0.5 0.00034 21.1 0.5 1.9 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain CFIA_Pcf11 PF11526.8 EGG16111.1 - 0.055 13.9 7.2 0.079 13.5 1.5 2.2 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 GLE1 PF07817.13 EGG16112.1 - 3e-51 174.1 3.1 3e-51 174.1 3.1 2.4 2 1 0 2 2 2 1 GLE1-like protein TMEM240 PF15207.6 EGG16112.1 - 0.0028 17.4 0.5 0.0084 15.8 0.5 1.8 1 1 0 1 1 1 1 TMEM240 family E1-E2_ATPase PF00122.20 EGG16113.1 - 5.3e-45 153.2 3.0 1.1e-44 152.1 3.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGG16113.1 - 1.4e-37 129.2 5.1 1.4e-37 129.2 5.1 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGG16113.1 - 2.8e-23 81.8 0.0 6.1e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGG16113.1 - 2.2e-19 70.6 0.0 5.3e-09 36.7 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGG16113.1 - 2.5e-18 65.5 0.0 7.1e-18 64.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG16113.1 - 5.3e-05 23.1 3.9 0.0027 17.5 0.1 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase FNIP PF05725.12 EGG16114.1 - 0.53 10.5 45.4 0.16 12.2 2.7 8.5 7 2 1 8 8 8 0 FNIP Repeat Med21 PF11221.8 EGG16114.1 - 7.7 6.8 9.1 12 6.1 0.3 2.7 2 0 0 2 2 2 0 Subunit 21 of Mediator complex adh_short PF00106.25 EGG16115.1 - 8.7e-24 84.1 3.0 2.4e-22 79.4 2.2 2.8 3 1 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG16115.1 - 6.7e-16 58.6 0.1 2.1e-14 53.7 0.1 2.8 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG16115.1 - 1.6e-06 28.1 0.2 3.3e-06 27.1 0.2 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG16115.1 - 3.2e-06 26.8 0.1 6.4e-06 25.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2722 PF10846.8 EGG16115.1 - 0.0035 16.4 7.6 0.0035 16.4 7.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 EGG16115.1 - 0.0083 15.2 18.7 0.0083 15.2 18.7 2.2 2 0 0 2 2 2 1 Transcriptional activator LAG-3 Spt20 PF12090.8 EGG16115.1 - 0.053 13.1 21.5 0.028 14.1 14.4 2.2 2 0 0 2 2 2 0 Spt20 family 3HCDH_N PF02737.18 EGG16115.1 - 0.09 12.6 0.2 0.09 12.6 0.2 2.1 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CIAPIN1 PF05093.13 EGG16115.1 - 0.21 12.1 6.1 2.2 8.9 0.4 2.5 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF2785 PF10978.8 EGG16115.1 - 1.1 8.9 5.6 0.33 10.7 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) Inj_translocase PF16928.5 EGG16115.1 - 2.5 7.5 17.3 2.5 7.5 1.7 2.5 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome WD40 PF00400.32 EGG16116.1 - 1.5e-13 51.0 6.8 0.00099 19.9 0.0 7.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG16116.1 - 4e-09 36.7 1.8 0.001 19.3 0.2 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGG16116.1 - 0.01 15.9 0.0 0.049 13.7 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region zinc_ribbon_2 PF13240.6 EGG16116.1 - 0.013 15.2 0.4 0.034 13.9 0.4 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 EGG16116.1 - 0.18 11.8 3.6 0.49 10.5 3.6 1.7 1 0 0 1 1 1 0 Double zinc ribbon Membralin PF09746.9 EGG16116.1 - 0.63 9.0 3.0 0.99 8.4 3.0 1.3 1 0 0 1 1 1 0 Tumour-associated protein NARP1 PF12569.8 EGG16116.1 - 4.7 6.0 8.2 7.9 5.3 8.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-ribbon_3 PF13248.6 EGG16116.1 - 7.7 6.1 7.9 0.79 9.2 2.8 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Cyt-b5 PF00173.28 EGG16117.1 - 5.3e-23 81.0 0.2 6.7e-23 80.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mpp10 PF04006.12 EGG16118.1 - 2.3e-139 465.7 92.1 3.7e-139 465.0 92.1 1.3 1 0 0 1 1 1 1 Mpp10 protein DUF63 PF01889.17 EGG16119.1 - 0.0041 17.4 1.0 0.0074 16.5 1.0 1.4 1 0 0 1 1 1 1 Membrane protein of unknown function DUF63 DUF4134 PF13572.6 EGG16119.1 - 0.0066 16.7 0.9 0.019 15.3 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4134) ABC2_membrane_3 PF12698.7 EGG16119.1 - 0.014 14.5 4.9 0.016 14.3 4.9 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein EptA_B_N PF08019.12 EGG16119.1 - 0.035 14.0 0.4 0.035 14.0 0.4 1.8 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB SUR7 PF06687.12 EGG16119.1 - 0.058 13.0 2.8 0.064 12.9 1.6 1.6 1 1 1 2 2 2 0 SUR7/PalI family DUF1218 PF06749.12 EGG16119.1 - 0.077 13.5 4.7 0.3 11.6 4.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) ETRAMP PF09716.10 EGG16119.1 - 0.77 9.9 4.4 2.6 8.2 0.0 2.8 3 1 1 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Rit1_C PF17184.4 EGG16120.1 - 9e-85 284.4 1.0 1.3e-84 283.8 1.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EGG16120.1 - 7.5e-17 61.6 0.2 1.6e-16 60.5 0.2 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain DSPc PF00782.20 EGG16120.1 - 0.053 13.3 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Exo_endo_phos PF03372.23 EGG16121.1 - 3.9e-08 33.1 0.1 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family CENP-B_dimeris PF09026.10 EGG16121.1 - 0.06 13.7 0.3 0.15 12.5 0.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cyclin PF08613.11 EGG16122.1 - 0.0022 18.4 0.1 0.0022 18.4 0.1 2.8 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 EGG16122.1 - 0.0034 17.1 0.1 0.0064 16.2 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Atg14 PF10186.9 EGG16123.1 - 2.1e-16 59.9 9.5 2.1e-16 59.9 9.5 1.7 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 EGG16123.1 - 1.3e-06 28.5 0.2 3.8e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Apg6 BARA domain zf-C4H2 PF10146.9 EGG16123.1 - 0.047 14.0 6.4 0.078 13.3 4.6 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein Mucin PF01456.17 EGG16123.1 - 1.6 8.7 19.3 2.7 8.0 19.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein EamA PF00892.20 EGG16124.1 - 4.5e-31 107.8 42.3 7.6e-16 58.5 17.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family Phage_integrase PF00589.22 EGG16125.1 - 3.3e-10 40.0 0.0 4.7e-10 39.5 0.0 1.3 1 1 0 1 1 1 1 Phage integrase family Peptidase_S10 PF00450.22 EGG16126.1 - 1.4e-99 334.4 4.1 1.6e-99 334.1 4.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1514 PF07438.11 EGG16126.1 - 0.26 11.2 0.6 0.48 10.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) DUF2726 PF10881.8 EGG16127.1 - 0.0012 18.7 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2726) DUF559 PF04480.12 EGG16127.1 - 0.006 16.4 2.2 0.16 11.8 0.5 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF559) HypA PF01155.19 EGG16127.1 - 0.03 14.3 0.5 0.03 14.3 0.5 2.8 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DRE2_N PF16803.5 EGG16127.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Peptidase_S10 PF00450.22 EGG16128.1 - 0.00012 21.6 0.2 0.00012 21.6 0.2 2.1 1 1 1 2 2 1 1 Serine carboxypeptidase CDC45 PF02724.14 EGG16128.1 - 0.0011 17.4 1.8 0.0012 17.3 1.8 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF494 PF04361.13 EGG16128.1 - 0.0015 18.5 1.4 0.0027 17.6 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF494) SID-1_RNA_chan PF13965.6 EGG16128.1 - 0.0016 16.9 5.6 0.0025 16.3 5.6 1.3 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Spt20 PF12090.8 EGG16128.1 - 0.0021 17.7 13.9 0.0036 16.9 13.9 1.5 1 0 0 1 1 1 1 Spt20 family DUF4834 PF16118.5 EGG16128.1 - 0.0083 17.1 7.4 0.0083 17.1 7.4 1.9 2 0 0 2 2 1 1 Domain of unknown function (DUF4834) CPSF100_C PF13299.6 EGG16128.1 - 0.014 15.5 2.9 0.02 15.1 2.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Gti1_Pac2 PF09729.9 EGG16128.1 - 0.016 15.3 5.2 0.022 14.9 5.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF5308 PF17233.2 EGG16128.1 - 0.019 15.2 0.1 0.023 14.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Connexin PF00029.19 EGG16128.1 - 0.024 14.4 2.8 0.046 13.5 2.8 1.5 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 EGG16128.1 - 0.038 12.9 1.6 0.056 12.4 1.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.22 EGG16128.1 - 0.039 13.2 1.6 0.058 12.6 1.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CLN3 PF02487.17 EGG16128.1 - 0.044 12.8 3.5 0.064 12.3 3.5 1.3 1 0 0 1 1 1 0 CLN3 protein DUF1764 PF08576.10 EGG16128.1 - 0.051 14.5 9.2 0.1 13.5 9.2 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3377 PF11857.8 EGG16128.1 - 0.055 13.4 0.2 0.055 13.4 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3377) TERB2 PF15101.6 EGG16128.1 - 0.1 12.6 8.9 0.15 12.1 8.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FAM176 PF14851.6 EGG16128.1 - 0.11 12.1 7.2 0.43 10.2 5.6 2.1 2 0 0 2 2 2 0 FAM176 family CSG2 PF16965.5 EGG16128.1 - 0.14 11.1 8.9 0.22 10.4 8.9 1.4 1 1 0 1 1 1 0 Ceramide synthase regulator RP-C_C PF11800.8 EGG16128.1 - 0.16 12.0 4.9 0.22 11.6 4.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region FAM60A PF15396.6 EGG16128.1 - 0.17 11.8 6.2 0.26 11.3 6.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Spore_III_AF PF09581.10 EGG16128.1 - 0.19 11.7 9.5 0.078 13.0 7.0 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Mem_trans PF03547.18 EGG16128.1 - 0.21 9.9 4.5 0.032 12.6 1.1 1.4 2 0 0 2 2 2 0 Membrane transport protein Pex14_N PF04695.13 EGG16128.1 - 0.34 11.6 8.2 0.56 10.8 8.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Roughex PF06020.11 EGG16128.1 - 0.66 9.0 9.2 0.9 8.6 9.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Ureide_permease PF07168.11 EGG16128.1 - 0.72 8.5 4.1 1.2 7.8 4.1 1.3 1 0 0 1 1 1 0 Ureide permease MAP17 PF15807.5 EGG16128.1 - 0.83 9.9 9.3 0.64 10.3 7.2 1.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 ALMT PF11744.8 EGG16128.1 - 1 8.1 8.6 1.4 7.6 8.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CobT PF06213.12 EGG16128.1 - 2.5 7.4 15.5 3.4 7.0 15.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Band_3_cyto PF07565.13 EGG16128.1 - 2.8 7.7 6.5 3.7 7.3 6.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4534 PF15049.6 EGG16128.1 - 3.1 7.5 9.6 0.11 12.2 0.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4534) Presenilin PF01080.17 EGG16128.1 - 5.2 5.7 14.8 0.078 11.7 7.7 1.5 2 0 0 2 2 2 0 Presenilin SprA-related PF12118.8 EGG16128.1 - 8.6 5.4 20.5 11 5.0 20.5 1.1 1 0 0 1 1 1 0 SprA-related family TIG PF01833.24 EGG16129.1 - 0.0046 17.0 5.1 0.0046 17.0 5.1 5.1 3 2 1 4 4 4 2 IPT/TIG domain LRR_8 PF13855.6 EGG16129.1 - 0.065 13.0 4.5 1 9.2 1.4 3.5 2 1 0 2 2 2 0 Leucine rich repeat MGC-24 PF05283.11 EGG16129.1 - 3.3 8.1 20.9 0.73 10.3 16.6 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin LRR_4 PF12799.7 EGG16129.1 - 3.6 8.1 11.4 25 5.5 3.8 5.0 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) DUF2183 PF09949.9 EGG16130.1 - 0.011 16.1 0.0 0.029 14.7 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) DUF2971 PF11185.8 EGG16131.1 - 9.9 7.4 8.5 28 6.0 8.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2971) LRR_2 PF07723.13 EGG16132.1 - 0.1 13.3 0.1 0.95 10.2 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich Repeat XTBD PF11952.8 EGG16132.1 - 0.11 12.2 0.1 0.81 9.5 0.0 2.3 2 0 0 2 2 2 0 XRN-Two Binding Domain, XTBD Secretin_N_2 PF07655.13 EGG16132.1 - 1.3 9.6 30.8 9.5 6.8 11.1 3.2 2 0 0 2 2 2 0 Secretin N-terminal domain DUF494 PF04361.13 EGG16133.1 - 0.059 13.3 0.9 0.14 12.0 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF494) Secretin_N_2 PF07655.13 EGG16134.1 - 1.4 9.5 22.4 0.28 11.8 10.5 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain Ras_bdg_2 PF14847.6 EGG16135.1 - 0.2 12.0 2.5 18 5.7 0.0 3.1 2 1 0 2 2 2 0 Ras-binding domain of Byr2 KcnmB2_inactiv PF09303.10 EGG16136.1 - 0.15 11.9 0.7 0.26 11.1 0.7 1.4 1 0 0 1 1 1 0 KCNMB2, ball and chain domain TerD PF02342.18 EGG16137.1 - 0.35 10.3 5.8 2 7.9 1.2 2.7 2 0 0 2 2 2 0 TerD domain Rieske PF00355.26 EGG16138.1 - 0.13 12.2 0.5 1.5 8.8 0.1 2.5 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain MoaC PF01967.21 EGG16139.1 - 3.1e-22 79.1 0.1 4.7e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 MoaC family AAA_24 PF13479.6 EGG16139.1 - 0.098 12.4 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF494 PF04361.13 EGG16140.1 - 0.25 11.2 2.8 0.2 11.5 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF494) Secretin_N_2 PF07655.13 EGG16140.1 - 2.8 8.6 20.7 3.6 8.2 10.3 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain Striatin PF08232.12 EGG16140.1 - 5.7 7.5 11.4 0.8 10.3 7.3 1.6 2 0 0 2 2 2 0 Striatin family SUIM_assoc PF16619.5 EGG16142.1 - 0.052 13.6 0.1 0.052 13.6 0.1 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Rxt3 PF08642.10 EGG16142.1 - 1.5 9.6 5.3 3.6 8.4 1.2 2.6 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 CDC24_OB3 PF17244.2 EGG16145.1 - 0.055 13.2 2.3 0.057 13.1 2.3 1.0 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 Sgf11 PF08209.11 EGG16147.1 - 5.5e-11 41.8 0.1 1e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) BB_PF PF18063.1 EGG16149.1 - 1.1e-43 149.3 1.1 2e-43 148.4 1.1 1.5 1 1 0 1 1 1 1 Beta barrel Pore-forming domain DUF4704 PF15787.5 EGG16150.1 - 1.8e-07 30.7 20.1 0.028 13.7 4.2 7.7 5 2 1 6 6 6 3 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 EGG16150.1 - 7.6e-07 29.4 0.0 3e-06 27.5 0.0 2.1 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Atrophin-1 PF03154.15 EGG16150.1 - 0.00011 20.7 1.2 0.00011 20.7 1.2 4.0 4 0 0 4 4 4 1 Atrophin-1 family DUF3944 PF13099.6 EGG16150.1 - 0.0018 18.1 0.0 0.0067 16.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3944) TFIIA PF03153.13 EGG16150.1 - 0.0027 17.8 16.9 0.0027 17.8 16.9 6.2 5 2 1 6 6 6 1 Transcription factor IIA, alpha/beta subunit NopRA1 PF16201.5 EGG16150.1 - 0.036 13.6 0.2 0.036 13.6 0.2 3.4 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Endotoxin_C PF03944.14 EGG16151.1 - 0.15 12.4 9.7 0.059 13.7 4.3 3.1 3 0 0 3 3 3 0 delta endotoxin EGF_2 PF07974.13 EGG16151.1 - 0.69 10.3 30.9 1.7 9.1 9.8 2.7 2 0 0 2 2 2 0 EGF-like domain D_CNTX PF17492.2 EGG16151.1 - 6.4 7.0 14.9 4.5 7.5 5.0 2.5 2 0 0 2 2 2 0 Delta Ctenitoxins Ank_2 PF12796.7 EGG16152.1 - 1.2e-22 80.3 0.5 5.5e-06 26.9 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG16152.1 - 1.9e-21 75.8 10.0 0.02 15.2 0.0 9.5 3 3 7 10 10 10 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG16152.1 - 1.2e-18 67.2 5.4 9.7e-05 22.8 0.1 7.4 3 3 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16152.1 - 1.1e-11 43.8 1.1 3.5 8.5 0.0 8.5 8 1 1 9 9 9 3 Ankyrin repeat Ank PF00023.30 EGG16152.1 - 0.00017 21.9 0.1 57 4.4 0.0 6.0 4 2 2 6 6 6 0 Ankyrin repeat SKG6 PF08693.10 EGG16153.1 - 0.023 14.1 0.5 0.053 12.9 0.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EGF_2 PF07974.13 EGG16153.1 - 0.94 9.9 30.9 2 8.9 9.8 2.7 2 0 0 2 2 2 0 EGF-like domain D_CNTX PF17492.2 EGG16153.1 - 6.4 7.0 14.7 4 7.7 4.8 2.5 2 0 0 2 2 2 0 Delta Ctenitoxins Hormone_5 PF00184.17 EGG16153.1 - 9.4 7.1 14.2 5.8 7.8 3.2 2.7 2 0 0 2 2 2 0 Neurohypophysial hormones, C-terminal Domain TPR_20 PF14561.6 EGG16154.1 - 2.6e-19 69.4 1.2 1.5e-18 66.9 0.2 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat Thioredoxin PF00085.20 EGG16154.1 - 3.3e-09 36.6 0.0 7.4e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 EGG16154.1 - 4.3e-06 26.8 0.1 8.9e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EGG16154.1 - 0.0018 18.7 0.1 0.074 13.5 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain ANAPC3 PF12895.7 EGG16154.1 - 0.012 15.8 0.6 0.54 10.5 0.2 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Lge1 PF11488.8 EGG16154.1 - 0.028 14.6 2.0 8.3 6.7 0.3 3.2 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 DUF1216 PF06746.11 EGG16154.1 - 0.029 14.4 1.8 0.062 13.3 0.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1216) TPR_8 PF13181.6 EGG16154.1 - 3.6 8.0 5.8 0.71 10.2 1.6 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGG16154.1 - 6.1 6.8 6.3 1.9 8.5 2.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SNF2_N PF00176.23 EGG16155.1 - 1.1e-65 221.6 0.2 1.1e-65 221.6 0.2 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 EGG16155.1 - 1.6e-44 151.5 19.6 1.6e-44 151.5 19.6 6.2 6 1 1 7 7 7 1 DNA-binding domain Helicase_C PF00271.31 EGG16155.1 - 6.6e-19 68.3 0.0 3.2e-18 66.1 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GST_N_3 PF13417.6 EGG16155.1 - 1.6e-10 41.3 0.0 4.4e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGG16155.1 - 3.1e-10 40.1 0.4 1.7e-09 37.7 0.4 2.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGG16155.1 - 4.8e-10 39.6 0.0 1.1e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGG16155.1 - 9.6e-09 35.4 0.0 4e-08 33.5 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG16155.1 - 1.4e-08 34.9 7.0 1.5e-08 34.7 0.0 3.9 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG16155.1 - 1.1e-06 28.5 0.0 3.3e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF4431 PF14485.6 EGG16158.1 - 0.15 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) ABC2_membrane_3 PF12698.7 EGG16160.1 - 0.19 10.8 0.3 0.18 10.9 0.3 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1828 PF08861.10 EGG16161.1 - 1.6 9.1 6.2 3.2 8.1 0.5 3.8 4 0 0 4 4 4 0 Domain of unknown function DUF1828 AMP-binding PF00501.28 EGG16162.1 - 1.6e-62 211.5 0.0 2.5e-62 210.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGG16162.1 - 8.8e-56 188.9 0.0 1.6e-55 188.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGG16162.1 - 5.5e-15 55.5 0.0 9.8e-14 51.4 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG16162.1 - 4.1e-09 35.9 0.0 1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 EGG16162.1 - 4.7e-06 26.9 0.1 1.2e-05 25.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EGG16162.1 - 4e-05 23.2 0.1 0.00019 20.9 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase ZZ PF00569.17 EGG16162.1 - 0.00062 19.5 6.9 0.0015 18.3 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type NAD_binding_10 PF13460.6 EGG16162.1 - 0.024 14.5 0.0 1.4 8.7 0.0 2.3 1 1 0 1 1 1 0 NAD(P)H-binding FYVE PF01363.21 EGG16162.1 - 0.081 13.1 0.7 0.22 11.7 0.7 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-UBR PF02207.20 EGG16162.1 - 0.094 12.9 3.5 0.26 11.5 3.5 1.7 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) GatB_Yqey PF02637.18 EGG16163.1 - 1.4e-17 64.0 0.2 2e-17 63.4 0.2 1.3 1 0 0 1 1 1 1 GatB domain DUF2226 PF09987.9 EGG16163.1 - 0.012 15.0 0.5 0.014 14.8 0.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) TIG PF01833.24 EGG16164.1 - 2.7e-15 56.2 23.6 8.7e-06 25.7 0.4 5.1 4 0 0 4 4 4 3 IPT/TIG domain Transthyretin PF00576.21 EGG16165.1 - 5.1e-34 117.3 0.1 5.8e-34 117.1 0.1 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family SdrD_B PF17210.3 EGG16165.1 - 0.0013 18.9 0.1 0.002 18.3 0.1 1.2 1 0 0 1 1 1 1 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG16165.1 - 0.0018 18.5 0.0 0.0026 18.0 0.0 1.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain C2 PF00168.30 EGG16166.1 - 3.9e-15 56.0 0.1 1.4e-14 54.2 0.0 1.9 1 1 1 2 2 2 1 C2 domain DUF2625 PF10946.8 EGG16166.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2625 PI3_PI4_kinase PF00454.27 EGG16167.1 - 5.4e-35 121.4 10.0 2.9e-34 119.0 0.1 4.1 4 1 0 4 4 4 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGG16167.1 - 0.8 9.1 8.3 0.14 11.6 1.9 2.6 3 0 0 3 3 3 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Menin PF05053.13 EGG16167.1 - 0.81 8.0 29.5 0.095 11.0 2.3 3.1 3 0 0 3 3 3 0 Menin SR-25 PF10500.9 EGG16167.1 - 4.5 6.8 34.4 2.9 7.5 7.9 3.5 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF3439 PF11921.8 EGG16167.1 - 7 6.6 31.5 0.14 12.1 8.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DEAD PF00270.29 EGG16168.1 - 1.3e-13 51.0 0.0 3.3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG16168.1 - 7.8e-11 42.3 0.2 6.4e-10 39.4 0.2 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 EGG16168.1 - 2.9e-07 31.0 0.0 6.8e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EGG16168.1 - 0.0087 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DUF4332 PF14229.6 EGG16168.1 - 0.015 15.5 0.0 0.051 13.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Cdd1 PF11731.8 EGG16168.1 - 0.031 14.5 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 Pathogenicity locus DUF2733 PF10813.8 EGG16168.1 - 0.055 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) AI-2E_transport PF01594.16 EGG16171.1 - 4.2 6.4 5.1 3.1 6.8 3.2 1.7 2 0 0 2 2 2 0 AI-2E family transporter M-inducer_phosp PF06617.13 EGG16172.1 - 0.082 12.2 0.7 0.12 11.6 0.7 1.2 1 0 0 1 1 1 0 M-phase inducer phosphatase DNA_III_psi PF03603.13 EGG16172.1 - 0.12 12.6 0.2 0.12 12.6 0.2 2.1 2 0 0 2 2 2 0 DNA polymerase III psi subunit TRAM_LAG1_CLN8 PF03798.16 EGG16173.1 - 1.2e-24 87.2 20.5 1.7e-24 86.7 20.5 1.2 1 0 0 1 1 1 1 TLC domain DUF4834 PF16118.5 EGG16173.1 - 0.018 16.0 1.6 0.018 16.0 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) adh_short_C2 PF13561.6 EGG16174.1 - 1.1e-63 214.9 0.3 1.3e-63 214.7 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG16174.1 - 1.8e-48 164.6 1.4 2.1e-48 164.4 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG16174.1 - 8.7e-14 51.8 0.6 1.2e-13 51.3 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG16174.1 - 0.00032 20.2 0.9 0.0087 15.6 0.9 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG16174.1 - 0.00076 18.6 1.8 0.0043 16.1 1.9 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGG16174.1 - 0.0014 17.8 0.4 0.0021 17.3 0.4 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein ATP_bind_2 PF03668.15 EGG16174.1 - 0.024 14.0 0.2 0.035 13.4 0.2 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family Exotox-A_cataly PF09009.10 EGG16174.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Exotoxin A catalytic ETRAMP PF09716.10 EGG16175.1 - 0.09 12.9 0.3 0.13 12.4 0.3 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) FNIP PF05725.12 EGG16176.1 - 2.1e-06 27.8 36.0 0.0012 18.9 3.2 9.1 5 3 3 8 8 8 6 FNIP Repeat TMEM208_SND2 PF05620.11 EGG16177.1 - 5.7e-49 166.1 0.9 6.4e-49 166.0 0.9 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 2TM PF13239.6 EGG16177.1 - 0.25 11.7 4.7 0.43 10.9 0.7 2.3 2 0 0 2 2 2 0 2TM domain Mitofilin PF09731.9 EGG16178.1 - 2.1e-31 109.5 37.9 6.1e-31 108.0 37.9 1.7 1 1 0 1 1 1 1 Mitochondrial inner membrane protein TTRAP PF14203.6 EGG16178.1 - 0.016 15.2 0.8 1.8 8.6 0.4 3.0 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Cation_ATPase_C PF00689.21 EGG16179.1 - 1.4e-45 155.2 3.4 1.4e-45 155.2 3.4 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGG16179.1 - 3.5e-41 140.7 0.2 3.5e-41 140.7 0.2 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGG16179.1 - 1.3e-17 64.8 0.7 2.7e-16 60.5 0.7 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG16179.1 - 8.4e-14 51.4 0.0 1.7e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGG16179.1 - 6.2e-12 45.0 0.0 1.3e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG16179.1 - 0.00051 19.9 0.1 0.00051 19.9 0.1 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Phage_holin_3_6 PF07332.11 EGG16179.1 - 0.22 11.5 6.6 0.81 9.8 2.3 2.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Wzy_C PF04932.15 EGG16179.1 - 0.59 9.7 6.1 4.7 6.8 0.1 3.2 3 0 0 3 3 3 0 O-Antigen ligase EGF_2 PF07974.13 EGG16180.1 - 3.2e-09 37.0 93.9 0.0095 16.3 13.6 5.6 5 0 0 5 5 5 5 EGF-like domain EGF_Tenascin PF18720.1 EGG16180.1 - 0.00092 19.2 11.5 0.00092 19.2 11.5 5.5 5 0 0 5 5 5 4 Tenascin EGF domain Pox_EPC_I2-L1 PF12575.8 EGG16180.1 - 0.31 11.3 2.1 7.8 6.8 0.1 3.0 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Transgly_assoc PF04226.13 EGG16180.1 - 0.76 10.1 12.9 4.8 7.5 0.4 3.8 3 0 0 3 3 3 0 Transglycosylase associated protein MAGI_u5 PF16666.5 EGG16180.1 - 2 8.6 4.5 1.6 8.9 0.0 3.0 3 0 0 3 3 3 0 Unstructured region on MAGI TFIIA PF03153.13 EGG16181.1 - 0.011 15.8 16.0 0.022 14.8 16.0 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAN_2 PF08276.11 EGG16182.1 - 0.04 14.0 1.8 0.04 14.0 1.8 2.4 2 0 0 2 2 2 0 PAN-like domain SE PF08491.10 EGG16183.1 - 0.044 12.8 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase CIMR PF00878.18 EGG16184.1 - 0.00025 21.1 0.4 0.039 14.0 0.1 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat C2 PF00168.30 EGG16185.1 - 8e-25 87.1 0.0 1.5e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain LRR_8 PF13855.6 EGG16185.1 - 2e-21 75.5 16.2 3e-08 33.3 0.2 4.8 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EGG16185.1 - 3.3e-19 68.7 30.6 5.2e-06 26.7 1.2 6.8 2 1 7 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGG16185.1 - 8.7e-05 22.6 22.9 3.7 8.5 0.2 8.9 8 1 0 8 8 8 3 Leucine Rich Repeat LRR_9 PF14580.6 EGG16185.1 - 0.00086 18.9 15.1 0.0074 15.8 0.9 4.0 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 EGG16185.1 - 0.005 16.8 13.5 17 5.8 0.0 7.2 7 0 0 7 7 7 1 Leucine Rich repeat DUF5572 PF17733.1 EGG16185.1 - 0.008 16.0 2.3 0.3 10.9 0.0 4.5 4 0 0 4 4 4 1 Family of unknown function (DUF5572) TFIIA PF03153.13 EGG16185.1 - 0.42 10.6 6.6 0.59 10.1 6.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UCH PF00443.29 EGG16186.1 - 7.5e-23 81.3 30.2 7.5e-23 81.3 30.2 3.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG16186.1 - 1.3e-18 67.7 1.1 1.3e-18 67.7 1.1 4.6 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Methyltransf_11 PF08241.12 EGG16188.1 - 4.6e-18 65.7 0.0 7.7e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG16188.1 - 1e-15 58.2 0.0 1.8e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG16188.1 - 3.4e-12 46.4 0.0 5.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG16188.1 - 7.6e-12 45.4 0.0 1.1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG16188.1 - 4.9e-11 43.2 0.0 9.2e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG16188.1 - 2.3e-07 30.4 0.0 3.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGG16188.1 - 6.7e-07 29.0 0.0 1.5e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EGG16188.1 - 4e-05 23.0 0.0 5.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_29 PF03141.16 EGG16188.1 - 0.00024 19.8 0.0 0.00031 19.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 EGG16188.1 - 0.0011 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EGG16188.1 - 0.0012 18.8 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGG16188.1 - 0.0013 18.2 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 EGG16188.1 - 0.0024 17.8 0.0 0.005 16.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 EGG16188.1 - 0.0031 17.2 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Met_10 PF02475.16 EGG16188.1 - 0.0083 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.19 EGG16188.1 - 0.032 14.3 0.0 0.068 13.3 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Epimerase PF01370.21 EGG16189.1 - 7.1e-19 68.2 0.1 1.2e-18 67.5 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGG16189.1 - 1.1e-13 51.0 0.1 6.4e-13 48.5 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EGG16189.1 - 1.1e-13 50.8 0.0 1.5e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGG16189.1 - 2.2e-10 40.5 0.1 2.9e-10 40.0 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EGG16189.1 - 1.3e-06 28.1 0.1 3.3e-06 26.9 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EGG16189.1 - 2e-06 27.8 0.0 2.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGG16189.1 - 0.00011 21.5 0.1 0.00016 20.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EGG16189.1 - 0.0034 16.9 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG16189.1 - 0.0041 17.1 0.1 0.013 15.4 0.1 1.7 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EGG16189.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain LRR_4 PF12799.7 EGG16190.1 - 0.34 11.4 19.2 6.4 7.4 2.5 6.5 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 EGG16191.1 - 2.3e-05 24.9 0.2 0.75 10.4 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG16191.1 - 0.021 15.3 7.0 6.1 7.8 0.1 6.1 7 0 0 7 7 7 0 Ankyrin repeat FNIP PF05725.12 EGG16192.1 - 0.0002 21.5 4.7 0.055 13.6 0.2 3.8 4 0 0 4 4 4 2 FNIP Repeat Ank_4 PF13637.6 EGG16193.1 - 1 10.1 3.5 92 3.8 0.0 5.7 6 2 2 8 8 8 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16193.1 - 1.6 9.6 9.6 43 5.1 0.0 7.0 8 0 0 8 8 8 0 Ankyrin repeat FSAP_sig_propep PF03032.15 EGG16193.1 - 7.9 6.6 6.7 19 5.4 6.7 1.6 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide Nitrophorin PF02087.15 EGG16195.1 - 0.061 13.3 0.0 0.081 12.9 0.0 1.1 1 0 0 1 1 1 0 Nitrophorin DUF687 PF05095.12 EGG16195.1 - 0.11 11.0 0.2 0.14 10.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF687) RTC4 PF14474.6 EGG16197.1 - 0.024 14.8 0.2 0.026 14.7 0.2 1.1 1 0 0 1 1 1 0 RTC4-like domain DUF2551 PF10826.8 EGG16197.1 - 0.08 13.2 0.1 0.28 11.5 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2551) LRR_4 PF12799.7 EGG16198.1 - 0.041 14.3 1.7 0.29 11.6 1.7 2.5 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) zf-BED PF02892.15 EGG16199.1 - 0.046 13.7 0.1 0.093 12.8 0.1 1.4 1 0 0 1 1 1 0 BED zinc finger DUF4290 PF14123.6 EGG16199.1 - 0.076 12.6 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4290) RVT_1 PF00078.27 EGG16201.1 - 2.8e-31 108.8 0.4 4.2e-31 108.2 0.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EGG16201.1 - 3.6e-17 62.2 0.0 8.2e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 EGG16201.1 - 3.4e-11 43.3 0.0 1.4e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH PF17917.1 EGG16201.1 - 9.7e-09 35.5 0.0 2.4e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nup188 PF10487.9 EGG16201.1 - 0.035 12.0 0.0 0.056 11.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 HEAT PF02985.22 EGG16202.1 - 4.5e-12 45.1 1.7 0.00038 20.5 0.0 7.2 8 0 0 8 8 7 2 HEAT repeat ParcG PF10274.9 EGG16202.1 - 1e-05 25.7 13.7 0.19 11.8 0.0 5.2 4 1 1 5 5 5 3 Parkin co-regulated protein HEAT_2 PF13646.6 EGG16202.1 - 3.6e-05 24.1 0.0 0.13 12.6 0.0 4.1 4 1 0 4 4 4 1 HEAT repeats Cnd1 PF12717.7 EGG16202.1 - 0.00049 20.2 1.2 0.00049 20.2 1.2 4.8 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGG16202.1 - 0.00099 19.7 5.4 0.0079 16.8 0.1 5.0 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGG16202.1 - 0.0033 17.9 0.1 0.99 10.0 0.1 3.4 3 0 0 3 3 3 1 HEAT-like repeat Telomere_reg-2 PF10193.9 EGG16202.1 - 0.004 17.6 7.1 0.072 13.5 0.1 4.5 5 0 0 5 5 5 1 Telomere length regulation protein Katanin_con80 PF13925.6 EGG16202.1 - 0.0099 15.9 0.9 0.085 12.9 0.9 2.7 1 0 0 1 1 1 1 con80 domain of Katanin RIX1 PF08167.12 EGG16202.1 - 0.027 14.2 0.6 0.027 14.2 0.6 3.8 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 EGG16202.1 - 0.1 12.7 6.0 0.55 10.4 0.7 4.0 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 EGG16202.1 - 0.38 10.7 6.2 0.46 10.4 0.2 3.2 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 EGG16202.1 - 3.8 7.0 14.0 0.32 10.5 0.1 3.9 5 1 1 6 6 6 0 CLASP N terminal MIF4G_like PF09088.11 EGG16204.1 - 1.9e-28 99.6 4.1 2e-28 99.5 0.9 2.6 3 1 0 3 3 3 1 MIF4G like MIF4G PF02854.19 EGG16204.1 - 4e-20 72.4 2.8 4e-20 72.4 2.8 1.7 2 0 0 2 2 2 1 MIF4G domain IFRD PF05004.13 EGG16204.1 - 0.028 13.5 0.2 0.44 9.6 0.1 2.1 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) FANCI_S2 PF14676.6 EGG16204.1 - 0.037 14.3 1.4 0.19 12.1 0.3 2.5 2 0 0 2 2 2 0 FANCI solenoid 2 Ank_2 PF12796.7 EGG16205.1 - 7.1e-31 106.6 13.2 1.5e-06 28.7 0.2 5.6 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16205.1 - 2.8e-22 78.8 12.7 0.001 19.6 0.1 8.9 4 3 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16205.1 - 1.3e-20 73.2 16.7 0.011 16.0 0.0 10.6 3 1 9 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16205.1 - 6.8e-20 69.1 7.7 1.1 10.0 0.0 11.7 9 3 3 12 12 12 6 Ankyrin repeat Ank PF00023.30 EGG16205.1 - 9.8e-07 29.0 3.1 66 4.2 0.0 8.6 4 2 3 7 7 7 0 Ankyrin repeat Dymeclin PF09742.9 EGG16206.1 - 3.8e-90 303.1 32.6 3.8e-90 303.1 32.6 1.5 2 0 0 2 2 2 1 Dyggve-Melchior-Clausen syndrome protein WD40 PF00400.32 EGG16207.1 - 1.3e-15 57.5 6.4 0.00038 21.2 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-C3HC4_3 PF13920.6 EGG16207.1 - 1.1e-07 31.5 4.0 2.4e-07 30.5 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG16207.1 - 1.6e-06 27.9 8.9 1.9e-06 27.6 7.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG16207.1 - 1.6e-06 28.0 7.0 1.7e-06 28.0 3.7 2.6 1 1 1 2 2 2 1 RING-type zinc-finger F-box-like PF12937.7 EGG16207.1 - 3.9e-06 26.7 0.1 8.4e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like zf-RING_5 PF14634.6 EGG16207.1 - 6e-06 26.1 8.0 1.5e-05 24.8 8.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGG16207.1 - 1.8e-05 25.0 8.8 6.4e-05 23.2 8.8 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGG16207.1 - 9.8e-05 22.2 7.5 9.8e-05 22.2 7.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) F-box PF00646.33 EGG16207.1 - 0.00019 21.2 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EGG16207.1 - 0.00061 18.6 6.5 0.041 12.5 0.7 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 zf-C3HC4_4 PF15227.6 EGG16207.1 - 0.00079 19.5 8.7 0.0022 18.1 8.7 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGG16207.1 - 0.0016 18.3 6.8 0.005 16.7 6.8 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGG16207.1 - 0.0045 16.8 4.6 0.0045 16.8 4.6 2.2 2 0 0 2 2 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGG16207.1 - 0.024 14.9 5.5 0.024 14.9 5.5 1.9 2 0 0 2 2 1 0 RING-H2 zinc finger domain DUF5046 PF16465.5 EGG16207.1 - 0.028 13.9 0.4 6 6.2 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5046) zf-ANAPC11 PF12861.7 EGG16207.1 - 4.4 7.4 7.7 1.6 8.8 4.3 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EGG16207.1 - 5.8 7.1 12.4 0.12 12.6 4.9 2.1 2 1 1 3 3 2 0 zinc RING finger of MSL2 RL11D PF11088.8 EGG16208.1 - 0.06 13.6 0.4 0.13 12.5 0.4 1.6 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Amastin PF07344.11 EGG16208.1 - 0.82 9.5 12.9 0.32 10.8 8.6 2.2 2 1 0 2 2 2 0 Amastin surface glycoprotein Macoilin PF09726.9 EGG16209.1 - 6.2e-05 21.8 17.8 9.9e-05 21.1 17.8 1.4 1 0 0 1 1 1 1 Macoilin family Arm PF00514.23 EGG16209.1 - 0.0021 18.0 0.1 0.31 11.1 0.1 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat ORF45 PF17620.2 EGG16209.1 - 0.0035 17.5 0.4 0.0084 16.2 0.4 1.6 1 0 0 1 1 1 1 Family of unknown function Zip PF02535.22 EGG16209.1 - 1.2 8.3 11.6 2.4 7.3 11.6 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter PALP PF00291.25 EGG16210.1 - 3.3e-69 233.5 0.1 4.6e-69 233.1 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EGG16210.1 - 5.2e-16 58.8 0.1 3.1e-09 37.1 0.0 3.1 2 1 0 2 2 2 2 CBS domain Fz PF01392.22 EGG16211.1 - 0.063 13.9 4.7 0.055 14.1 3.2 1.7 1 1 1 2 2 2 0 Fz domain 2-Hacid_dh_C PF02826.19 EGG16212.1 - 5.3e-52 175.7 0.0 2.1e-51 173.8 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGG16212.1 - 1.1e-32 112.5 0.0 1.6e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PAP2 PF01569.21 EGG16212.1 - 3e-11 43.2 2.6 3e-11 43.2 2.6 2.5 3 0 0 3 3 3 1 PAP2 superfamily NAD_binding_2 PF03446.15 EGG16212.1 - 1.1e-05 25.6 0.1 2.9e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase PAP2_3 PF14378.6 EGG16212.1 - 2.3e-05 24.2 5.7 2.3e-05 24.2 5.7 1.9 2 0 0 2 2 2 1 PAP2 superfamily XdhC_C PF13478.6 EGG16212.1 - 0.0074 16.8 0.0 0.018 15.5 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain IlvN PF07991.12 EGG16212.1 - 0.089 12.4 0.0 0.29 10.7 0.0 1.9 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Oxidored_nitro PF00148.19 EGG16212.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase CH PF00307.31 EGG16214.1 - 5.2e-33 113.5 5.6 4.1e-20 72.0 0.1 3.5 4 0 0 4 4 4 2 Calponin homology (CH) domain DUF4234 PF14018.6 EGG16214.1 - 0.025 14.7 0.1 0.075 13.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) DUF4834 PF16118.5 EGG16214.1 - 0.033 15.1 0.8 0.16 13.0 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CH_2 PF06294.11 EGG16214.1 - 0.043 13.9 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EGG16214.1 - 0.065 13.1 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 CAMSAP CH domain CAF1 PF04857.20 EGG16215.1 - 1.3e-20 73.9 4.7 4.5e-10 39.2 0.0 3.1 3 1 0 3 3 3 2 CAF1 family ribonuclease COX6B PF02297.17 EGG16215.1 - 9.7e-15 54.6 1.3 9.7e-15 54.6 1.3 1.8 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb Sporozoite_P67 PF05642.11 EGG16215.1 - 2.7e-05 22.5 8.2 3.6e-05 22.1 8.2 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Apt1 PF10351.9 EGG16215.1 - 0.18 10.6 7.3 0.23 10.3 7.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EGG16215.1 - 0.34 9.4 10.5 0.42 9.1 10.5 1.1 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 EGG16215.1 - 0.67 8.9 4.7 0.91 8.4 4.7 1.1 1 0 0 1 1 1 0 Mitoguardin DUF1635 PF07795.11 EGG16215.1 - 2.3 8.0 6.7 3.7 7.3 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) CX9C PF16860.5 EGG16215.1 - 2.4 8.2 4.7 4.6 7.3 3.3 2.0 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Menin PF05053.13 EGG16215.1 - 2.5 6.4 8.0 3.3 5.9 8.0 1.1 1 0 0 1 1 1 0 Menin Tmemb_cc2 PF10267.9 EGG16215.1 - 6.5 5.8 5.9 8.8 5.3 5.9 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein FAD_binding_3 PF01494.19 EGG16216.1 - 2.4e-19 69.8 0.5 8.8e-09 35.1 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGG16216.1 - 0.00096 19.3 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG16216.1 - 0.0067 15.7 0.1 0.031 13.5 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DbpA PF03880.15 EGG16216.1 - 0.078 13.0 1.3 0.97 9.5 0.0 2.8 3 0 0 3 3 3 0 DbpA RNA binding domain Zip PF02535.22 EGG16217.1 - 2.3 7.4 17.3 0.09 12.0 8.1 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Presenilin PF01080.17 EGG16217.1 - 9.5 4.9 17.4 0.24 10.2 9.1 2.1 2 0 0 2 2 2 0 Presenilin Ribosomal_L21p PF00829.21 EGG16218.1 - 2e-31 108.3 1.2 2.6e-31 107.8 1.2 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Fip1 PF05182.13 EGG16219.1 - 1.9e-21 75.3 1.0 3.1e-21 74.6 1.0 1.3 1 0 0 1 1 1 1 Fip1 motif Pkinase PF00069.25 EGG16220.1 - 4.9e-51 173.6 0.0 4.5e-50 170.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16220.1 - 5.2e-14 52.2 0.0 8.9e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG16220.1 - 9.5e-06 25.7 0.0 2.5e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Mucin PF01456.17 EGG16220.1 - 0.04 13.9 7.0 0.039 14.0 3.5 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Kinase-like PF14531.6 EGG16220.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGG16220.1 - 0.11 11.8 0.3 0.22 10.8 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Borrelia_orfX PF04160.12 EGG16223.1 - 0.0059 16.6 0.4 0.012 15.6 0.4 1.5 1 0 0 1 1 1 1 Orf-X protein Ank_5 PF13857.6 EGG16225.1 - 0.00062 20.0 0.4 28 5.2 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16225.1 - 0.00069 19.9 2.3 8.1 7.4 0.1 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EGG16225.1 - 0.2 12.3 2.4 14 6.4 0.1 4.8 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG16226.1 - 0.011 16.3 5.0 13 6.5 0.1 4.6 4 1 2 6 6 6 0 Ankyrin repeats (3 copies) Glypican PF01153.19 EGG16227.1 - 8.3 5.1 12.7 0.99 8.2 4.3 2.1 1 1 1 2 2 2 0 Glypican RicinB_lectin_2 PF14200.6 EGG16228.1 - 0.28 11.9 3.2 0.27 12.0 0.2 2.5 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like CoA_trans PF01144.23 EGG16229.1 - 8e-110 365.4 11.5 1.5e-71 240.2 0.6 3.2 4 0 0 4 4 4 2 Coenzyme A transferase CDC45 PF02724.14 EGG16230.1 - 2.4e-166 554.8 39.1 9.6e-165 549.5 39.1 2.5 1 1 0 1 1 1 1 CDC45-like protein Spt5_N PF11942.8 EGG16230.1 - 0.00069 20.6 29.7 0.00069 20.6 29.7 2.8 2 0 0 2 2 1 1 Spt5 transcription elongation factor, acidic N-terminal NINJA_B PF16136.5 EGG16230.1 - 0.0084 16.5 11.6 0.025 14.9 11.6 1.7 1 0 0 1 1 1 1 Putative nuclear localisation signal Nop14 PF04147.12 EGG16230.1 - 0.054 11.7 51.0 0.082 11.1 51.0 1.2 1 0 0 1 1 1 0 Nop14-like family CCSAP PF15748.5 EGG16230.1 - 0.075 13.2 27.2 0.12 12.5 27.2 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Nop53 PF07767.11 EGG16230.1 - 0.089 12.2 49.7 0.17 11.2 49.7 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) LAP1C PF05609.12 EGG16230.1 - 0.33 10.0 24.9 0.062 12.4 21.6 1.4 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) TFIIF_alpha PF05793.12 EGG16230.1 - 2 6.9 55.4 4.1 5.9 55.4 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 EGG16230.1 - 3.1 7.1 60.3 5.2 6.4 60.3 1.3 1 0 0 1 1 1 0 SDA1 Atg14 PF10186.9 EGG16230.1 - 3.8 6.5 18.4 7.1 5.6 18.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NEMP PF10225.9 EGG16230.1 - 4.5 6.9 5.7 10 5.7 5.7 1.5 1 0 0 1 1 1 0 NEMP family SLC12 PF03522.15 EGG16230.1 - 4.7 6.1 21.3 8.1 5.3 21.3 1.4 1 0 0 1 1 1 0 Solute carrier family 12 BUD22 PF09073.10 EGG16230.1 - 6.2 6.0 52.4 10 5.3 52.4 1.2 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.7 EGG16230.1 - 7.1 4.6 22.9 13 3.7 22.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Methyltransf_2 PF00891.18 EGG16231.1 - 5.4e-40 136.9 0.0 8.9e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EGG16231.1 - 0.0018 18.2 0.0 0.0041 17.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Dimerisation2 PF16864.5 EGG16231.1 - 0.0028 17.6 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_11 PF08241.12 EGG16231.1 - 0.024 15.3 0.0 0.047 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGG16231.1 - 0.028 15.2 0.0 0.053 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGG16231.1 - 0.028 15.1 0.0 0.065 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGG16231.1 - 0.035 13.9 0.0 0.094 12.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Ank_2 PF12796.7 EGG16233.1 - 1.1e-08 35.5 0.3 0.0002 21.9 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16233.1 - 3.7e-06 27.4 4.0 3e-05 24.5 0.1 4.3 5 1 0 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16233.1 - 0.00017 21.8 1.6 0.95 10.2 0.0 5.8 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 EGG16233.1 - 0.062 13.6 3.4 1.4 9.3 0.0 4.3 5 1 1 6 6 6 0 Ankyrin repeats (many copies) Ank PF00023.30 EGG16233.1 - 0.064 13.7 1.5 2.8 8.6 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat PAP_assoc PF03828.19 EGG16234.1 - 3.6e-11 43.1 0.5 1.2e-10 41.5 0.5 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGG16234.1 - 0.00081 19.6 0.1 0.0044 17.3 0.1 2.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Mst1_SARAH PF11629.8 EGG16234.1 - 0.0011 19.0 0.1 0.017 15.2 0.0 2.7 2 0 0 2 2 2 1 C terminal SARAH domain of Mst1 Polbeta PF18765.1 EGG16234.1 - 0.013 15.5 0.5 0.24 11.5 0.0 3.1 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase Helicase_C_3 PF13625.6 EGG16234.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain FliD_N PF02465.18 EGG16234.1 - 0.17 12.6 1.7 0.69 10.6 0.3 2.9 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF5525 PF17663.1 EGG16234.1 - 2.8 5.9 16.3 4.4 5.2 16.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5525) FlxA PF14282.6 EGG16234.1 - 7.6 6.6 6.7 9.4 6.3 0.9 2.6 2 0 0 2 2 2 0 FlxA-like protein Hemerythrin PF01814.23 EGG16235.1 - 9.2e-12 45.7 0.3 1.4e-11 45.2 0.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Myosin_head PF00063.21 EGG16236.1 - 5.4e-253 841.2 9.1 5.4e-253 841.2 9.1 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 EGG16236.1 - 3e-23 82.1 1.2 3e-23 82.1 1.2 3.5 3 0 0 3 3 3 1 DIL domain Myosin_N PF02736.19 EGG16236.1 - 1.2e-09 37.8 3.7 2.3e-09 36.9 3.7 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 EGG16236.1 - 1e-05 24.9 9.9 0.009 15.7 0.5 5.2 5 0 0 5 5 5 2 IQ calmodulin-binding motif UPF0242 PF06785.11 EGG16236.1 - 0.0051 16.9 26.2 0.0051 16.9 26.2 4.0 3 1 1 4 4 4 1 Uncharacterised protein family (UPF0242) N-terminus AAA_16 PF13191.6 EGG16236.1 - 0.11 12.8 0.0 0.11 12.8 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 EGG16236.1 - 0.26 11.6 0.0 0.26 11.6 0.0 3.2 2 1 0 2 2 2 0 AAA domain CTD_bind PF04818.13 EGG16237.1 - 0.03 15.1 4.7 2.4 9.1 0.1 4.4 4 0 0 4 4 4 0 RNA polymerase II-binding domain. NUC173 PF08161.12 EGG16237.1 - 0.25 11.0 3.0 16 5.1 0.0 3.5 2 1 1 3 3 3 0 NUC173 domain Nucleo_P87 PF07267.11 EGG16238.1 - 0.059 12.2 2.3 0.066 12.1 2.3 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 WRNPLPNID PF15017.6 EGG16238.1 - 3.2 8.7 9.2 2e+02 2.9 9.2 2.2 1 1 0 1 1 1 0 Putative WW-binding domain and destruction box FNIP PF05725.12 EGG16240.1 - 0.0089 16.2 15.3 0.019 15.1 0.7 5.1 5 2 1 6 6 6 3 FNIP Repeat F-box-like PF12937.7 EGG16240.1 - 0.15 12.0 0.2 0.4 10.6 0.2 1.7 1 0 0 1 1 1 0 F-box-like GST_N_3 PF13417.6 EGG16242.1 - 1.2e-12 48.0 0.0 2.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGG16242.1 - 1.3e-11 44.7 0.0 2.4e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGG16242.1 - 1.2e-10 41.5 0.0 3.5e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG16242.1 - 3.1e-09 36.9 0.0 5.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG16242.1 - 4.9e-08 33.1 0.0 8.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG16242.1 - 7.3e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ank_2 PF12796.7 EGG16244.1 - 0.00086 19.9 1.0 0.31 11.7 0.1 4.3 4 1 0 4 4 2 1 Ankyrin repeats (3 copies) Sec62 PF03839.16 EGG16244.1 - 0.034 13.7 8.8 0.03 13.8 6.3 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 Ank_5 PF13857.6 EGG16244.1 - 0.038 14.3 0.2 22 5.5 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DUF572 PF04502.13 EGG16244.1 - 0.043 13.5 13.7 0.017 14.8 9.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) Ank_3 PF13606.6 EGG16244.1 - 0.044 14.4 0.4 9.7 7.1 0.0 4.3 4 0 0 4 4 2 0 Ankyrin repeat Ank_4 PF13637.6 EGG16244.1 - 0.05 14.2 2.4 12 6.6 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeats (many copies) FHIPEP PF00771.20 EGG16244.1 - 0.2 10.1 5.2 0.22 9.9 2.4 2.0 2 0 0 2 2 2 0 FHIPEP family Zip PF02535.22 EGG16244.1 - 0.53 9.5 4.8 1.1 8.4 4.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.17 EGG16244.1 - 0.77 9.9 6.9 0.35 11.0 3.7 2.0 2 0 0 2 2 2 0 DDHD domain REC114-like PF15165.6 EGG16244.1 - 0.86 9.3 10.4 0.24 11.2 4.4 2.4 2 1 1 3 3 3 0 Meiotic recombination protein REC114-like EIIBC-GUT_N PF03612.14 EGG16244.1 - 2 8.1 7.2 4.9 6.9 5.8 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus AIF_C PF14721.6 EGG16244.1 - 2.1 8.7 8.7 0.79 10.1 5.3 2.0 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Connexin PF00029.19 EGG16244.1 - 2.6 7.8 13.5 4 7.1 10.7 2.2 2 0 0 2 2 2 0 Connexin FAM176 PF14851.6 EGG16244.1 - 3.3 7.4 8.5 2.6 7.7 6.1 1.9 2 0 0 2 2 2 0 FAM176 family BSMAP PF12280.8 EGG16244.1 - 5.6 7.1 7.0 2.1 8.5 2.2 2.4 2 0 0 2 2 2 0 Brain specific membrane anchored protein Gti1_Pac2 PF09729.9 EGG16244.1 - 5.6 7.0 17.4 1.3 9.1 11.8 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family CPSF100_C PF13299.6 EGG16244.1 - 7.5 6.7 13.3 0.94 9.6 8.0 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal OTU PF02338.19 EGG16245.1 - 4.2e-23 82.2 0.1 4.2e-23 82.2 0.1 2.5 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGG16245.1 - 2.3e-07 30.5 0.1 2.3e-07 30.5 0.1 3.2 3 1 0 3 3 3 1 Peptidase C65 Otubain GRAM PF02893.20 EGG16245.1 - 0.00059 19.7 0.2 0.0023 17.8 0.2 2.0 1 0 0 1 1 1 1 GRAM domain 3-PAP PF12578.8 EGG16245.1 - 1.2 8.9 0.0 1.2 8.9 0.0 4.4 4 2 1 5 5 5 0 Myotubularin-associated protein Aldedh PF00171.22 EGG16246.1 - 1.1e-80 271.4 0.0 1.4e-80 271.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family T6SS_HCP PF05638.12 EGG16246.1 - 6.5e-07 29.8 0.0 1.5e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ArfGap PF01412.18 EGG16247.1 - 1.8e-36 124.7 0.1 3.9e-36 123.7 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 EGG16247.1 - 2e-18 66.8 0.6 3.7e-18 66.0 0.6 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGG16247.1 - 0.00012 22.4 2.2 0.00068 20.0 0.8 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 EGG16247.1 - 0.00039 20.5 0.2 0.00069 19.7 0.2 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EGG16247.1 - 0.065 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain TcdB_N PF12918.7 EGG16247.1 - 0.93 9.8 7.9 2.7 8.3 7.9 1.7 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain DHHC PF01529.20 EGG16248.1 - 3e-30 105.0 27.3 3e-30 105.0 27.3 3.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF4013 PF13197.6 EGG16248.1 - 0.00017 21.4 5.7 0.0015 18.4 0.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4013) CdvA PF18822.1 EGG16249.1 - 0.051 13.4 2.9 0.14 11.9 0.6 2.4 2 1 0 2 2 2 0 CdvA-like coiled-coil domain PrpR_N PF06506.11 EGG16249.1 - 0.13 11.8 0.1 22 4.6 0.0 2.8 3 0 0 3 3 3 0 Propionate catabolism activator Prominin PF05478.11 EGG16249.1 - 0.16 9.9 1.4 0.67 7.8 0.1 1.9 1 1 1 2 2 2 0 Prominin NBD94 PF16830.5 EGG16249.1 - 0.18 12.2 2.4 16 6.0 0.1 3.0 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH MH2 PF03166.14 EGG16250.1 - 0.09 13.0 0.1 0.35 11.1 0.0 1.9 2 1 1 3 3 3 0 MH2 domain Pkinase PF00069.25 EGG16251.1 - 2.5e-29 102.4 0.1 6e-29 101.2 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16251.1 - 5.8e-22 78.2 0.0 4e-20 72.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG16251.1 - 0.00028 19.8 0.0 0.00069 18.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EGG16251.1 - 0.003 16.6 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RNA12 PF10443.9 EGG16251.1 - 0.016 14.0 0.1 0.046 12.5 0.0 1.7 2 0 0 2 2 2 0 RNA12 protein DUF3978 PF13123.6 EGG16251.1 - 0.032 14.0 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3978) Kdo PF06293.14 EGG16251.1 - 0.056 12.8 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cadherin_5 PF17892.1 EGG16252.1 - 0.16 11.9 4.0 0.78 9.8 0.0 3.3 3 0 0 3 3 3 0 Cadherin-like domain PNRC PF15365.6 EGG16252.1 - 8.6 6.3 6.0 2.1 8.3 1.9 2.2 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator motif Pkinase PF00069.25 EGG16253.1 - 2e-36 125.7 0.0 4.1e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16253.1 - 1.1e-28 100.3 0.0 2.4e-28 99.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase AAA_16 PF13191.6 EGG16253.1 - 6e-07 30.0 0.0 1.3e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Kinase-like PF14531.6 EGG16253.1 - 1.3e-06 27.9 0.0 0.0004 19.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like AAA_22 PF13401.6 EGG16253.1 - 0.0012 19.2 0.1 0.0062 16.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGG16253.1 - 0.0017 18.3 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 EGG16253.1 - 0.0033 17.4 0.0 0.12 12.3 0.0 2.7 2 1 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 EGG16253.1 - 0.004 17.7 0.1 0.012 16.1 0.1 1.9 1 0 0 1 1 1 1 ABC transporter KAP_NTPase PF07693.14 EGG16253.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.6 EGG16253.1 - 0.021 14.6 0.5 0.052 13.3 0.5 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FISNA PF14484.6 EGG16253.1 - 0.11 12.7 0.9 0.28 11.4 0.1 2.0 2 0 0 2 2 2 0 Fish-specific NACHT associated domain Sigma54_activat PF00158.26 EGG16253.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 EGG16253.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Atg14 PF10186.9 EGG16254.1 - 0.0094 15.1 4.3 0.0094 15.1 4.3 2.2 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Rootletin PF15035.6 EGG16254.1 - 0.0099 15.9 21.0 0.12 12.4 6.0 2.4 2 0 0 2 2 2 2 Ciliary rootlet component, centrosome cohesion FCH PF00611.23 EGG16254.1 - 0.012 15.8 1.9 0.012 15.8 1.9 2.6 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain LELP1 PF15042.6 EGG16254.1 - 0.037 14.4 0.9 0.84 10.1 0.1 2.4 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 Exonuc_VII_L PF02601.15 EGG16254.1 - 0.04 13.5 19.3 0.11 12.0 3.3 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit SKA1 PF07160.12 EGG16254.1 - 2.3 8.0 30.4 0.28 11.0 2.5 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 FtsH_ext PF06480.15 EGG16254.1 - 3.2 8.1 7.0 7.6 6.9 3.8 2.7 1 1 1 2 2 2 0 FtsH Extracellular Rubrerythrin PF02915.17 EGG16254.1 - 3.3 8.1 8.6 1.4 9.3 0.7 3.1 2 1 1 3 3 3 0 Rubrerythrin Phlebovirus_NSM PF07246.11 EGG16254.1 - 4.1 6.7 13.8 0.95 8.8 1.7 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Membralin PF09746.9 EGG16254.1 - 4.4 6.2 8.8 0.35 9.9 3.0 1.9 2 0 0 2 2 2 0 Tumour-associated protein Baculo_p24 PF05073.12 EGG16254.1 - 4.6 7.0 13.2 3.4 7.4 0.7 2.4 2 0 0 2 2 2 0 Baculovirus P24 capsid protein FSA_C PF10479.9 EGG16254.1 - 6 4.9 14.3 10 4.1 14.3 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dimer_Tnp_hAT PF05699.14 EGG16255.1 - 5.3e-06 26.1 0.1 5.3e-06 26.1 0.1 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-C2H2_3 PF13878.6 EGG16255.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO CID_GANP PF16766.5 EGG16255.1 - 0.044 14.0 0.0 0.25 11.5 0.0 2.4 1 0 0 1 1 1 0 Binding region of GANP to ENY2 RPN6_N PF18055.1 EGG16255.1 - 1.3 9.4 9.4 0.17 12.3 4.4 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain FtsH_ext PF06480.15 EGG16255.1 - 1.8 9.0 6.0 18 5.7 2.3 3.3 2 0 0 2 2 2 0 FtsH Extracellular DUF2321 PF10083.9 EGG16255.1 - 5.1 6.7 10.2 2.6 7.7 0.2 3.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2321) F-box-like PF12937.7 EGG16256.1 - 0.022 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 F-box-like IMUP PF15761.5 EGG16256.1 - 9.4 7.0 12.8 18 6.0 12.8 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein FNIP PF05725.12 EGG16260.1 - 1.3e-05 25.3 3.7 0.079 13.1 0.0 6.3 7 1 0 7 7 7 2 FNIP Repeat FNIP PF05725.12 EGG16261.1 - 2.4 8.4 18.0 9.4 6.5 0.1 6.6 8 2 1 9 9 9 0 FNIP Repeat DUF4263 PF14082.6 EGG16263.1 - 0.063 13.5 0.3 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) FNIP PF05725.12 EGG16265.1 - 0.00015 21.9 29.7 0.017 15.3 0.5 9.3 7 1 4 11 11 11 5 FNIP Repeat DUF3909 PF13077.6 EGG16265.1 - 0.0087 16.2 0.8 0.054 13.7 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3909) SIN1_PH PF16979.5 EGG16265.1 - 0.019 15.2 0.6 3.6 7.9 0.1 3.1 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology NOA36 PF06524.12 EGG16265.1 - 4 6.7 8.1 7.3 5.8 8.1 1.3 1 0 0 1 1 1 0 NOA36 protein PSI PF01437.25 EGG16266.1 - 0.013 16.1 1.8 0.023 15.2 1.8 1.4 1 0 0 1 1 1 0 Plexin repeat FNIP PF05725.12 EGG16266.1 - 0.067 13.4 21.1 0.14 12.4 0.2 6.1 6 1 0 6 6 6 0 FNIP Repeat Paramecium_SA PF01508.16 EGG16266.1 - 0.36 11.3 1.9 0.76 10.2 1.9 1.4 1 0 0 1 1 1 0 Paramecium surface antigen domain DNase_II PF03265.15 EGG16267.1 - 1.5e-18 67.2 2.5 2e-16 60.2 0.1 3.4 3 0 0 3 3 3 3 Deoxyribonuclease II Pkinase PF00069.25 EGG16268.1 - 7.4e-65 218.9 0.0 1.4e-64 218.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16268.1 - 1.4e-49 168.7 0.0 2.6e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG16268.1 - 3.1e-05 23.4 0.0 0.00061 19.2 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGG16268.1 - 0.056 12.2 0.0 0.056 12.2 0.0 1.9 2 1 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 EGG16268.1 - 0.064 12.9 2.8 2.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 TFIIA PF03153.13 EGG16268.1 - 0.14 12.1 22.8 0.26 11.3 22.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec15 PF04091.12 EGG16269.1 - 2.4e-53 181.6 7.8 2.4e-53 181.6 7.8 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 EGG16269.1 - 0.015 15.3 0.6 0.015 15.3 0.6 3.3 3 0 0 3 3 3 0 Vps51/Vps67 Sec8_exocyst PF04048.14 EGG16269.1 - 0.015 15.1 1.5 0.015 15.1 1.5 3.5 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain COG5 PF10392.9 EGG16269.1 - 0.027 14.6 0.2 0.027 14.6 0.2 3.6 3 1 1 4 4 4 0 Golgi transport complex subunit 5 Cofilin_ADF PF00241.20 EGG16271.1 - 1.7e-25 89.2 0.0 1.9e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Copine PF07002.16 EGG16272.1 - 3.7e-53 180.2 0.0 6e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGG16272.1 - 1.7e-25 89.3 0.3 8.2e-12 45.3 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGG16272.1 - 0.00022 21.4 0.1 0.00049 20.3 0.0 1.6 2 0 0 2 2 2 1 vWA found in TerF C terminus Pro-kuma_activ PF09286.11 EGG16273.1 - 3.1e-27 95.6 0.7 7.1e-27 94.4 0.7 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF2456 PF10445.9 EGG16273.1 - 0.16 12.0 0.5 0.61 10.2 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2456) Fibrillin_U_N PF18193.1 EGG16273.1 - 8 6.7 8.5 0.22 11.7 1.9 1.8 2 0 0 2 2 2 0 Fibrillin 1 unique N-terminal domain FMO-like PF00743.19 EGG16275.1 - 6.3e-54 183.3 0.2 8.9e-54 182.8 0.2 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGG16275.1 - 1.9e-17 63.5 0.2 1.8e-12 47.2 0.2 3.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGG16275.1 - 4.7e-16 58.9 0.0 5.5e-14 52.1 0.0 1.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG16275.1 - 2.1e-07 31.4 0.4 0.037 14.6 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGG16275.1 - 2e-06 27.2 4.2 6.6e-05 22.2 0.7 2.9 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGG16275.1 - 9.9e-06 25.7 0.0 2.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG16275.1 - 0.00011 22.0 6.8 0.016 14.8 6.8 3.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGG16275.1 - 0.03 14.3 0.0 0.14 12.1 0.0 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EGG16275.1 - 0.036 13.4 0.1 0.32 10.3 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EGG16275.1 - 0.13 11.5 0.3 0.28 10.5 0.1 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase TFIIA PF03153.13 EGG16277.1 - 0.9 9.5 26.5 0.058 13.4 21.4 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RabGAP-TBC PF00566.18 EGG16278.1 - 3.8e-47 160.7 7.4 3.8e-47 160.7 7.4 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EGG16278.1 - 0.00034 20.3 2.3 0.22 11.5 0.2 4.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EGG16278.1 - 0.00088 18.7 0.8 0.0037 16.7 0.8 2.2 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGG16278.1 - 0.013 16.0 3.7 0.26 11.7 0.4 3.0 2 0 0 2 2 2 0 EF-hand domain pair Ribonuc_2-5A PF06479.12 EGG16278.1 - 0.15 12.2 2.8 11 6.2 0.0 3.2 3 0 0 3 3 3 0 Ribonuclease 2-5A GNAT_acetyltran PF12746.7 EGG16278.1 - 0.15 11.6 2.1 0.13 11.8 0.2 1.8 2 0 0 2 2 2 0 GNAT acetyltransferase SpoIIIAH PF12685.7 EGG16278.1 - 0.75 9.6 11.9 0.21 11.4 2.8 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein CLN3 PF02487.17 EGG16278.1 - 0.87 8.6 5.8 0.27 10.3 1.9 2.0 2 0 0 2 2 2 0 CLN3 protein BSP_II PF05432.11 EGG16278.1 - 2.7 7.6 23.9 0.21 11.2 14.5 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) SOG2 PF10428.9 EGG16278.1 - 4 6.5 32.2 0.79 8.9 5.9 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein Helicase_C PF00271.31 EGG16279.1 - 5.5e-17 62.1 1.6 7.6e-16 58.4 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EGG16279.1 - 1.1e-15 57.4 0.4 4.1e-15 55.6 0.4 2.0 1 0 0 1 1 1 1 Bromodomain SNF2_N PF00176.23 EGG16279.1 - 7.3e-12 44.7 0.1 1.5e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain QLQ PF08880.11 EGG16279.1 - 3.6e-06 26.6 0.2 1e-05 25.2 0.2 1.8 1 0 0 1 1 1 1 QLQ HSA PF07529.13 EGG16279.1 - 0.00039 20.7 9.5 0.00039 20.7 9.5 3.3 3 0 0 3 3 3 1 HSA SnAC PF14619.6 EGG16279.1 - 0.0061 17.1 0.4 0.0061 17.1 0.4 5.1 4 2 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex HrcA_DNA-bdg PF03444.15 EGG16279.1 - 0.022 14.4 0.3 0.087 12.5 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding AT_hook PF02178.19 EGG16279.1 - 2.4 8.3 6.0 7.8 6.7 6.0 2.0 1 0 0 1 1 1 0 AT hook motif adh_short_C2 PF13561.6 EGG16280.1 - 1.4e-41 142.6 0.1 5e-40 137.5 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG16280.1 - 1.6e-41 141.9 1.9 3.2e-40 137.7 1.9 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG16280.1 - 8.7e-10 38.8 0.1 1.4e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG16280.1 - 1.5e-05 24.6 0.0 0.00012 21.6 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EGG16280.1 - 0.00012 21.4 0.0 0.033 13.5 0.0 2.3 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EGG16280.1 - 0.048 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EGG16280.1 - 0.049 13.3 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF5607 PF18355.1 EGG16281.1 - 0.09 13.2 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5607) F-box PF00646.33 EGG16282.1 - 0.04 13.8 0.2 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 EGG16282.1 - 0.055 13.4 0.6 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 F-box-like Vps5 PF09325.10 EGG16283.1 - 4.4e-56 190.1 10.9 4.4e-56 190.1 10.9 1.7 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 EGG16283.1 - 1.8e-24 85.9 0.8 1.8e-24 85.9 0.8 1.8 2 0 0 2 2 2 1 PX domain RPW8 PF05659.11 EGG16283.1 - 0.006 16.3 2.9 0.37 10.5 0.0 3.2 3 0 0 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Sec8_exocyst PF04048.14 EGG16283.1 - 0.014 15.3 4.6 3.3 7.6 0.1 3.2 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain TRPM_tetra PF16519.5 EGG16283.1 - 0.084 13.0 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 Tetramerisation domain of TRPM HsbA PF12296.8 EGG16283.1 - 0.33 11.4 2.2 27 5.2 0.1 3.7 2 2 2 4 4 4 0 Hydrophobic surface binding protein A Laminin_II PF06009.12 EGG16283.1 - 0.48 10.4 4.2 7.1 6.7 0.0 3.1 2 1 0 2 2 2 0 Laminin Domain II Nbl1_Borealin_N PF10444.9 EGG16283.1 - 0.91 9.2 6.2 18 5.0 0.1 3.4 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal ERG2_Sigma1R PF04622.12 EGG16284.1 - 4.3e-59 199.4 0.0 5.6e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein NS3_envE PF02723.14 EGG16284.1 - 0.026 14.6 1.3 0.054 13.6 1.3 1.5 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E Acetyltransf_1 PF00583.25 EGG16285.1 - 4.7e-07 30.1 0.0 6.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG16285.1 - 5.6e-05 23.1 0.0 8.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG16285.1 - 6.6e-05 23.3 0.0 0.0001 22.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EGG16285.1 - 0.0015 18.7 0.0 0.0021 18.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGG16285.1 - 0.013 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RA PF00788.23 EGG16285.1 - 0.025 15.2 0.0 0.17 12.6 0.0 2.2 1 1 2 3 3 3 0 Ras association (RalGDS/AF-6) domain FNIP PF05725.12 EGG16286.1 - 3.1e-24 84.8 19.9 2.7e-06 27.4 0.0 8.4 4 3 2 7 7 7 5 FNIP Repeat LRR_8 PF13855.6 EGG16286.1 - 0.024 14.4 0.2 0.024 14.4 0.2 4.5 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.6 EGG16286.1 - 4.6 7.6 11.3 40 4.6 0.1 5.2 4 0 0 4 4 4 0 Leucine Rich repeat PBP PF01161.20 EGG16287.1 - 5.6e-17 62.3 0.1 7.3e-17 61.9 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RhoGAP PF00620.27 EGG16288.1 - 3.2e-44 150.4 0.5 1.1e-43 148.7 0.5 2.0 1 0 0 1 1 1 1 RhoGAP domain SUIM_assoc PF16619.5 EGG16288.1 - 0.0043 17.1 0.4 0.0043 17.1 0.4 5.0 4 0 0 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 JAB PF01398.21 EGG16290.1 - 6.5e-10 39.0 0.0 6.5e-10 39.0 0.0 2.8 4 0 0 4 4 4 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EGG16290.1 - 0.002 17.9 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain FANCI_S2 PF14676.6 EGG16290.1 - 0.65 10.3 6.2 3 8.1 0.5 3.3 2 1 0 2 2 2 0 FANCI solenoid 2 SapB_1 PF05184.15 EGG16291.1 - 1.7e-08 34.3 6.4 1.7e-08 34.3 6.4 2.2 2 0 0 2 2 2 1 Saposin-like type B, region 1 SapB_2 PF03489.17 EGG16291.1 - 0.0031 17.6 0.1 0.0086 16.2 0.1 1.8 1 0 0 1 1 1 1 Saposin-like type B, region 2 Erf4 PF10256.9 EGG16292.1 - 0.014 15.5 0.1 0.019 15.1 0.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family CbiK PF06180.11 EGG16292.1 - 0.023 14.0 0.1 0.034 13.5 0.1 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Erf4 PF10256.9 EGG16293.1 - 0.00082 19.5 0.3 0.0016 18.5 0.3 1.5 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF1325 PF07039.11 EGG16294.1 - 2.2e-33 115.2 0.5 5e-33 114.0 0.5 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 EGG16294.1 - 9.6e-07 28.6 0.4 2.5e-06 27.3 0.1 1.9 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 EGG16294.1 - 0.0002 21.0 0.0 0.00061 19.4 0.0 1.9 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 DUF4537 PF15057.6 EGG16294.1 - 0.0017 18.4 0.1 0.016 15.2 0.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 EGG16294.1 - 0.0088 15.8 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 2 Lamin-B receptor of TUDOR domain DUF5641 PF18701.1 EGG16294.1 - 0.084 13.0 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5641) Exonuc_VII_L PF02601.15 EGG16295.1 - 0.0011 18.6 4.7 0.0018 17.9 4.7 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF3584 PF12128.8 EGG16295.1 - 0.0033 15.0 14.5 0.0048 14.5 14.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DivIVA PF05103.13 EGG16295.1 - 0.0076 16.3 16.3 0.0076 16.3 16.3 2.0 2 0 0 2 2 2 1 DivIVA protein PBP1_TM PF14812.6 EGG16295.1 - 0.0093 16.3 7.9 0.0093 16.3 7.9 2.2 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4715 PF15835.5 EGG16295.1 - 0.098 12.7 2.7 0.2 11.7 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) CENP-B_dimeris PF09026.10 EGG16295.1 - 0.11 12.9 14.8 0.27 11.7 14.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3926 PF13080.6 EGG16295.1 - 0.26 11.3 3.3 0.22 11.5 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) Leu_zip PF15294.6 EGG16295.1 - 0.27 10.7 21.8 1.1 8.8 21.8 1.9 1 1 0 1 1 1 0 Leucine zipper APG6_N PF17675.1 EGG16295.1 - 0.27 11.7 24.8 0.57 10.7 24.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 EGG16295.1 - 0.34 10.3 19.5 0.61 9.5 19.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 EGG16295.1 - 0.64 10.2 23.3 1.2 9.3 20.6 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Tropomyosin_1 PF12718.7 EGG16295.1 - 1.9 8.7 25.3 1.3 9.2 19.5 2.3 1 1 1 2 2 2 0 Tropomyosin like ERM PF00769.19 EGG16295.1 - 3.7 7.3 31.6 0.35 10.6 25.8 2.1 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Ank_2 PF12796.7 EGG16299.1 - 1.5e-38 131.2 4.5 1.3e-08 35.3 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16299.1 - 2.5e-28 98.1 2.3 7.5e-07 29.6 0.1 6.0 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16299.1 - 1.7e-23 80.1 3.3 0.0002 21.5 0.0 9.3 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EGG16299.1 - 1.8e-23 82.3 5.9 1e-07 32.1 0.0 7.7 3 3 5 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 EGG16299.1 - 3.9e-22 77.7 8.6 4.4e-05 23.7 0.0 9.3 8 1 0 8 8 8 4 Ankyrin repeat Acp26Ab PF05777.12 EGG16299.1 - 0.002 18.8 2.0 1.1 10.0 1.3 2.5 2 0 0 2 2 2 2 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) CdAMP_rec PF06153.11 EGG16299.1 - 0.093 12.9 0.7 45 4.3 0.0 3.9 4 0 0 4 4 4 0 Cyclic-di-AMP receptor I_LWEQ PF01608.17 EGG16302.1 - 8.9e-66 220.8 199.3 4.2e-46 157.0 8.0 19.7 6 4 11 20 20 20 11 I/LWEQ domain FERM_f0 PF16511.5 EGG16302.1 - 5.3e-28 97.2 0.1 1.5e-25 89.3 0.1 3.1 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 EGG16302.1 - 2.1e-25 89.4 5.2 2.2e-25 89.4 0.0 3.8 3 1 0 3 3 3 1 FERM central domain FERM_N PF09379.10 EGG16302.1 - 7.2e-16 57.9 0.1 2.9e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 FERM N-terminal domain VHP PF02209.19 EGG16302.1 - 1.1e-14 54.2 0.8 1.1e-14 54.2 0.8 2.4 3 0 0 3 3 3 1 Villin headpiece domain VBS PF08913.10 EGG16302.1 - 0.00047 20.6 18.4 0.00076 19.9 3.5 13.9 13 2 2 15 15 15 5 Vinculin Binding Site Complex1_49kDa PF00346.19 EGG16302.1 - 0.088 11.9 3.6 2.7 7.0 0.1 3.5 4 0 0 4 4 4 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit XhlA PF10779.9 EGG16302.1 - 0.54 10.5 2.3 3.3 8.0 0.0 3.8 2 0 0 2 2 2 0 Haemolysin XhlA DUF919 PF06034.11 EGG16302.1 - 0.64 9.9 4.0 1.7 8.5 2.6 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) RIP PF00161.19 EGG16302.1 - 3.2 7.3 8.7 0.56 9.8 1.0 3.4 3 0 0 3 3 3 0 Ribosome inactivating protein SipA_VBS PF17985.1 EGG16302.1 - 9.5 6.3 13.1 13 5.9 0.1 6.1 5 0 0 5 5 5 0 SipA vinculin binding site bZIP_1 PF00170.21 EGG16303.1 - 0.077 13.1 13.1 2.3 8.4 0.3 2.5 2 0 0 2 2 2 0 bZIP transcription factor DUF2249 PF10006.9 EGG16303.1 - 0.28 11.1 1.2 0.79 9.6 1.2 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) HALZ PF02183.18 EGG16303.1 - 1.6 9.0 10.6 2.6 8.3 0.6 2.8 2 1 0 2 2 2 0 Homeobox associated leucine zipper RhoGEF PF00621.20 EGG16305.1 - 1.8e-47 162.0 8.1 3.3e-47 161.1 8.1 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF3439 PF11921.8 EGG16305.1 - 0.0084 16.1 8.6 0.0084 16.1 8.6 3.4 2 1 1 3 3 3 1 Domain of unknown function (DUF3439) DZR PF12773.7 EGG16305.1 - 0.0095 15.9 18.0 0.02 14.9 18.0 1.6 1 0 0 1 1 1 1 Double zinc ribbon PH PF00169.29 EGG16305.1 - 0.026 15.0 0.4 0.2 12.2 0.0 2.7 2 0 0 2 2 2 0 PH domain PocR PF10114.9 EGG16305.1 - 0.062 13.1 4.3 0.17 11.6 4.3 1.7 1 0 0 1 1 1 0 Sensory domain found in PocR PH_13 PF16652.5 EGG16305.1 - 0.2 11.5 1.9 1.1 9.1 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain UDPGT PF00201.18 EGG16307.1 - 5e-07 28.9 0.0 1e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 EGG16307.1 - 0.14 12.2 0.0 1.6 8.8 0.0 2.6 2 1 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain Phytochelatin_C PF09328.10 EGG16307.1 - 0.31 10.4 2.3 0.53 9.6 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1984) 60KD_IMP PF02096.20 EGG16308.1 - 8.2e-16 58.3 1.2 1.4e-15 57.5 1.2 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein PIF2 PF04631.12 EGG16308.1 - 0.099 11.5 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Per os infectivity factor 2 C2 PF00168.30 EGG16311.1 - 1e-21 77.2 0.0 2.3e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain Arf PF00025.21 EGG16312.1 - 4.7e-39 133.6 0.0 5.3e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG16312.1 - 4.7e-11 43.0 0.2 2.6e-10 40.5 0.2 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGG16312.1 - 3.1e-09 36.5 0.0 4.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGG16312.1 - 1.5e-08 34.2 0.5 3.2e-07 29.9 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit Ras PF00071.22 EGG16312.1 - 2.8e-08 33.5 0.0 5.1e-08 32.7 0.0 1.3 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGG16312.1 - 1.4e-07 31.6 0.0 2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGG16312.1 - 4.4e-06 26.2 0.0 5.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGG16312.1 - 0.1 12.1 0.2 0.36 10.4 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.6 EGG16312.1 - 0.17 11.4 0.0 0.24 11.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF463 PF04317.12 EGG16312.1 - 0.18 10.7 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 AbfS_sensor PF18225.1 EGG16312.1 - 0.22 11.5 0.1 0.41 10.6 0.1 1.5 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain ATP-synt_DE_N PF02823.16 EGG16313.1 - 1.6e-14 53.5 0.0 2.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain NYD-SP28 PF14772.6 EGG16313.1 - 0.057 13.5 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Sperm tail Isochorismatase PF00857.20 EGG16314.1 - 3.5e-39 134.8 0.1 3.9e-39 134.6 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family CT_C_D PF02682.16 EGG16314.1 - 0.041 13.6 0.0 0.053 13.3 0.0 1.1 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D T4_deiodinase PF00837.17 EGG16314.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase Mak10 PF04112.13 EGG16315.1 - 3.3e-14 52.8 0.3 5.6e-11 42.2 0.0 2.8 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Swi3 PF07962.12 EGG16317.1 - 1.6e-06 28.0 0.0 3.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 SSP160 PF06933.11 EGG16317.1 - 0.044 12.0 7.9 0.017 13.3 2.5 2.2 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 FNIP PF05725.12 EGG16318.1 - 0.29 11.3 20.1 1.4 9.1 0.0 6.1 6 1 1 7 7 7 0 FNIP Repeat FNIP PF05725.12 EGG16319.1 - 0.0035 17.5 3.9 3.3 8.0 0.2 3.9 3 1 1 4 4 4 2 FNIP Repeat GATase_7 PF13537.6 EGG16323.1 - 0.053 13.4 0.2 0.089 12.7 0.2 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain AAA PF00004.29 EGG16324.1 - 0.00012 22.5 0.0 0.00025 21.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGG16324.1 - 0.0046 17.0 0.1 0.016 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_35 PF14516.6 EGG16324.1 - 0.0054 15.6 0.2 0.43 9.4 0.0 2.5 2 1 1 3 3 3 2 AAA-like domain UBA_2 PF08587.11 EGG16324.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) IBR PF01485.21 EGG16325.1 - 1.8e-19 69.7 38.7 4e-14 52.6 9.9 4.2 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EGG16325.1 - 0.00024 20.9 1.1 0.00024 20.9 1.1 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG16325.1 - 0.00028 20.9 2.1 0.00028 20.9 2.1 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG16325.1 - 0.00028 20.7 1.8 0.00028 20.7 1.8 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG16325.1 - 0.0011 19.2 4.3 0.0011 19.2 4.3 4.2 2 1 1 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 EGG16325.1 - 0.0039 17.0 3.3 0.0039 17.0 3.3 4.4 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 Ank_4 PF13637.6 EGG16327.1 - 2.7e-23 82.0 6.7 0.0055 17.3 0.1 9.1 7 2 2 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16327.1 - 1.4e-17 63.5 3.4 0.05 13.9 0.0 9.2 6 4 4 11 11 11 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG16327.1 - 7.5e-17 61.7 2.4 0.00036 21.1 0.0 6.3 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG16327.1 - 2.2e-15 55.2 5.0 2.2 9.1 0.0 10.6 10 1 1 11 11 11 3 Ankyrin repeat DUF249 PF03158.13 EGG16327.1 - 1.3e-05 25.0 0.6 2.1 8.0 0.0 4.7 4 1 1 5 5 5 2 Multigene family 530 protein DUF3447 PF11929.8 EGG16327.1 - 2.2e-05 24.3 18.8 0.24 11.4 0.1 6.6 1 1 4 6 6 6 3 Domain of unknown function (DUF3447) Ank PF00023.30 EGG16327.1 - 0.0054 17.1 0.2 2.3e+02 2.5 0.0 6.2 5 1 0 5 5 5 0 Ankyrin repeat DUF4087 PF13316.6 EGG16327.1 - 0.36 11.3 2.8 10 6.7 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4087) RNase_P_p30 PF01876.16 EGG16327.1 - 0.76 9.2 3.2 56 3.1 0.0 4.2 4 1 1 5 5 5 0 RNase P subunit p30 FucT_N PF18025.1 EGG16329.1 - 0.01 16.3 1.3 0.019 15.4 0.2 2.1 2 0 0 2 2 2 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain SR-25 PF10500.9 EGG16330.1 - 0.89 9.1 8.3 2.6 7.6 8.3 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PA26 PF04636.13 EGG16331.1 - 3.5e-162 540.3 0.1 4.4e-162 540.0 0.1 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Lin-8 PF03353.15 EGG16331.1 - 0.17 11.5 3.5 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF2281 PF10047.9 EGG16332.1 - 0.17 12.6 0.6 67 4.3 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2281) BAG PF02179.16 EGG16332.1 - 0.19 12.1 0.9 1.4 9.4 0.5 2.4 2 0 0 2 2 2 0 BAG domain FixP_N PF14715.6 EGG16332.1 - 0.28 11.0 4.2 0.6 9.9 4.2 1.6 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Cwf_Cwc_15 PF04889.12 EGG16332.1 - 1.1 9.0 15.2 0.11 12.2 10.4 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF5331 PF17265.2 EGG16332.1 - 4.3 7.1 6.6 64 3.3 0.2 5.0 3 1 1 4 4 4 0 Family of unknown function (DUF5331) NOA36 PF06524.12 EGG16332.1 - 4.8 6.4 6.2 8.3 5.6 6.2 1.3 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.32 EGG16333.1 - 1.8e-22 79.2 21.4 4.9e-07 30.3 0.5 10.0 11 0 0 11 11 11 3 WD domain, G-beta repeat HELP PF03451.14 EGG16333.1 - 3e-12 46.2 0.0 5.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 HELP motif ANAPC4_WD40 PF12894.7 EGG16333.1 - 4.7e-11 42.8 6.3 0.0015 18.8 0.1 6.5 2 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGG16333.1 - 4.3e-05 23.5 0.2 0.004 17.2 0.0 3.8 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Utp8 PF10395.9 EGG16333.1 - 0.0011 17.6 0.5 0.01 14.4 0.1 2.3 2 0 0 2 2 2 1 Utp8 family RAB3GAP2_N PF14655.6 EGG16333.1 - 0.013 14.8 0.1 0.49 9.6 0.0 3.1 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PD40 PF07676.12 EGG16333.1 - 0.017 15.0 0.1 13 5.9 0.1 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF3642 PF12182.8 EGG16333.1 - 0.058 13.7 3.4 1.3 9.3 0.1 3.8 4 0 0 4 4 4 0 Bacterial lipoprotein ATP-synt_DE_N PF02823.16 EGG16333.1 - 0.13 12.1 0.3 27 4.8 0.0 2.7 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_Eps PF04627.13 EGG16334.1 - 5.1e-18 64.8 0.4 6.9e-18 64.4 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Peptidase_M24 PF00557.24 EGG16335.1 - 6.3e-52 176.3 0.1 7.8e-52 176.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EGG16335.1 - 1.3e-11 44.7 10.3 2.9e-11 43.5 10.3 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 EGG16335.1 - 0.001 18.9 5.6 0.0022 17.8 5.6 1.6 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EGG16335.1 - 0.0031 17.6 5.6 0.0063 16.6 5.6 1.6 1 0 0 1 1 1 1 MYND finger DZR PF12773.7 EGG16335.1 - 0.64 10.1 7.7 2 8.5 7.7 1.9 1 0 0 1 1 1 0 Double zinc ribbon tRNA_SAD PF07973.14 EGG16336.1 - 1.9e-05 24.7 0.0 4.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PAP2 PF01569.21 EGG16337.1 - 2.7e-23 82.2 2.3 2.7e-23 82.2 2.3 2.2 1 1 1 2 2 2 1 PAP2 superfamily Spt20 PF12090.8 EGG16337.1 - 0.0025 17.5 8.6 0.0025 17.5 8.6 2.2 2 0 0 2 2 2 1 Spt20 family CSG2 PF16965.5 EGG16337.1 - 0.027 13.4 2.1 0.034 13.1 0.2 1.9 2 0 0 2 2 2 0 Ceramide synthase regulator Connexin PF00029.19 EGG16337.1 - 0.042 13.6 3.6 2.4 7.8 0.5 2.6 2 0 0 2 2 2 0 Connexin Pex14_N PF04695.13 EGG16337.1 - 2.2 8.9 15.7 22 5.7 0.0 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MRI PF15325.6 EGG16337.1 - 4.7 8.3 8.1 0.48 11.5 0.7 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection YesK PF14150.6 EGG16337.1 - 5.1 7.4 11.5 0.81 9.9 1.9 2.7 3 0 0 3 3 3 0 YesK-like protein Abhydrolase_1 PF00561.20 EGG16338.1 - 5e-09 36.2 0.2 1.9e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold SR-25 PF10500.9 EGG16338.1 - 2.5 7.7 10.4 3.6 7.1 10.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase_Tyr PF07714.17 EGG16339.1 - 1.9e-38 132.2 0.0 5.3e-25 88.2 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EGG16339.1 - 5.1e-37 127.7 0.0 1.3e-35 123.0 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain RhoGEF PF00621.20 EGG16339.1 - 3.8e-23 82.7 4.7 3.8e-23 82.7 4.7 2.7 3 1 0 3 3 3 1 RhoGEF domain Kdo PF06293.14 EGG16339.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pup_ligase PF03136.15 EGG16339.1 - 0.053 12.6 0.5 0.078 12.0 0.5 1.2 1 0 0 1 1 1 0 Pup-ligase protein C2 PF00168.30 EGG16340.1 - 1.8e-16 60.3 0.1 7.2e-16 58.4 0.0 1.8 1 1 1 2 2 2 1 C2 domain hSac2 PF12456.8 EGG16342.1 - 0.0041 16.8 1.0 0.14 11.9 0.1 2.3 2 0 0 2 2 2 2 Inositol phosphatase Glyco_hydro_9 PF00759.19 EGG16343.1 - 3.1e-112 376.0 17.7 4.3e-112 375.6 17.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 SOG2 PF10428.9 EGG16343.1 - 0.23 10.6 20.3 0.34 10.0 20.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 EGG16343.1 - 3 7.7 10.5 4 7.2 10.5 1.2 1 0 0 1 1 1 0 SPX domain TatD_DNase PF01026.21 EGG16344.1 - 6.1e-32 111.0 0.0 7.4e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Coiled PF05710.12 EGG16345.1 - 0.00028 21.6 1.9 0.00033 21.4 1.9 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 EGG16346.1 - 0.027 15.3 5.2 0.033 15.0 5.2 1.1 1 0 0 1 1 1 0 Coiled coil Coiled PF05710.12 EGG16347.1 - 0.00082 20.2 3.6 0.00099 19.9 3.6 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 EGG16348.1 - 0.012 16.4 4.6 0.014 16.2 4.6 1.1 1 0 0 1 1 1 0 Coiled coil Coiled PF05710.12 EGG16350.1 - 0.002 18.9 4.4 0.0024 18.7 4.4 1.1 1 0 0 1 1 1 1 Coiled coil Csm1_N PF18504.1 EGG16352.1 - 0.0077 16.5 3.2 0.0077 16.5 3.2 13.8 5 3 10 15 15 15 2 Csm1 N-terminal domain SLT_L PF14718.6 EGG16352.1 - 1.1 9.5 5.1 0.81 9.9 0.6 3.0 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain ERCC4 PF02732.15 EGG16353.1 - 8.9e-17 61.7 0.0 8.9e-17 61.7 0.0 4.5 4 1 0 4 4 4 1 ERCC4 domain PTE PF02126.18 EGG16354.1 - 0.0012 18.4 0.6 0.0012 18.4 0.6 1.7 2 0 0 2 2 2 1 Phosphotriesterase family Clathrin-link PF09268.10 EGG16354.1 - 0.012 15.0 0.7 1.8 8.0 0.0 3.0 3 0 0 3 3 3 0 Clathrin, heavy-chain linker STAR_dimer PF16544.5 EGG16354.1 - 0.063 12.9 7.7 0.98 9.0 0.3 3.1 3 0 0 3 3 3 0 Homodimerisation region of STAR domain protein YlbD_coat PF14071.6 EGG16354.1 - 0.32 11.3 5.7 1.2 9.3 0.1 3.0 2 2 0 2 2 2 0 Putative coat protein DRE2_N PF16803.5 EGG16354.1 - 0.36 11.1 4.1 2.2 8.5 0.1 3.2 2 1 0 3 3 3 0 Fe-S cluster assembly protein DRE2 N-terminus MA3 PF02847.17 EGG16355.1 - 4.4e-27 94.3 0.4 1e-26 93.1 0.4 1.7 1 0 0 1 1 1 1 MA3 domain Pro_isomerase PF00160.21 EGG16356.1 - 2.3e-50 171.0 0.8 3.5e-50 170.4 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 EGG16356.1 - 2.9e-05 23.6 9.3 2.9e-05 23.6 9.3 3.2 2 2 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 EGG16356.1 - 5.8e-05 23.2 0.1 0.00022 21.3 0.1 2.0 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein SR-25 PF10500.9 EGG16356.1 - 0.0053 16.4 27.7 0.24 11.0 10.1 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein SWI-SNF_Ssr4 PF08549.10 EGG16356.1 - 1.1 7.8 19.2 0.37 9.4 4.6 2.0 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Ecl1 PF12855.7 EGG16356.1 - 1.8 9.7 20.2 2.4 9.3 6.1 2.2 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Chorion_2 PF03964.15 EGG16356.1 - 7.9 7.4 6.6 5.3 7.9 1.2 2.3 2 0 0 2 2 2 0 Chorion family 2 DUF3446 PF11928.8 EGG16356.1 - 8 6.9 20.2 10 6.5 4.6 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Dmrt1 PF12374.8 EGG16356.1 - 9.1 6.8 15.6 7.7 7.0 3.7 2.5 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Diphthamide_syn PF01866.17 EGG16357.1 - 6.4e-120 400.2 0.2 8.1e-120 399.8 0.2 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Colicin_immun PF09204.10 EGG16357.1 - 1.8 9.1 4.5 11 6.6 0.0 3.2 3 0 0 3 3 3 0 Bacterial self-protective colicin-like immunity DUF4576 PF15144.6 EGG16359.1 - 0.2 11.5 0.1 0.36 10.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4576) BRF1 PF07741.13 EGG16360.1 - 0.22 11.9 8.2 0.24 11.8 8.2 1.0 1 0 0 1 1 1 0 Brf1-like TBP-binding domain CLN3 PF02487.17 EGG16360.1 - 0.23 10.5 3.5 0.23 10.5 3.5 1.0 1 0 0 1 1 1 0 CLN3 protein EphA2_TM PF14575.6 EGG16360.1 - 1.1 10.2 4.4 1.4 9.8 4.4 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 EGG16360.1 - 1.6 9.8 9.0 1.7 9.6 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 EGG16360.1 - 2 7.1 5.7 1.9 7.1 5.7 1.0 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 EGG16360.1 - 2.7 7.6 26.3 2.6 7.6 26.3 1.0 1 0 0 1 1 1 0 Spt20 family PigN PF04987.14 EGG16360.1 - 4 6.2 6.9 4.3 6.1 6.9 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) TMEM208_SND2 PF05620.11 EGG16360.1 - 6.6 6.5 9.4 7.4 6.3 9.4 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 RRM_5 PF13893.6 EGG16362.1 - 3.1e-29 101.1 0.0 1.5e-22 79.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EGG16362.1 - 2.1e-25 88.3 0.0 5.6e-08 32.5 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 EGG16362.1 - 6.4e-15 55.1 0.1 1.3e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 RRM-like domain DUF4637 PF15470.6 EGG16362.1 - 0.12 12.1 4.9 0.21 11.3 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Hamartin PF04388.12 EGG16362.1 - 0.34 9.5 18.6 0.56 8.8 18.6 1.3 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.25 EGG16363.1 - 1e-75 254.5 0.0 1.6e-75 253.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16363.1 - 2e-54 184.6 0.0 3.1e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG16363.1 - 6.4e-06 25.2 1.9 1.6e-05 23.9 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGG16363.1 - 0.0068 15.9 1.7 0.0081 15.7 0.3 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 EGG16363.1 - 0.0098 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGG16363.1 - 0.037 14.0 0.0 1.4 8.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family HBS1_N PF08938.10 EGG16364.1 - 0.032 14.5 1.9 0.18 12.2 0.0 2.6 2 0 0 2 2 2 0 HBS1 N-terminus CUE PF02845.16 EGG16364.1 - 0.12 12.1 1.7 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 CUE domain PARP PF00644.20 EGG16365.1 - 1.3e-52 178.2 0.6 2.5e-52 177.3 0.0 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGG16365.1 - 2.5e-38 131.2 0.4 4.7e-38 130.4 0.4 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain PADR1 PF08063.12 EGG16365.1 - 3e-17 62.1 0.5 3e-17 62.1 0.5 1.9 2 0 0 2 2 2 1 PADR1 (NUC008) domain WGR PF05406.15 EGG16365.1 - 1.1e-15 57.4 0.1 3.7e-15 55.7 0.1 1.9 1 0 0 1 1 1 1 WGR domain zf-PARP PF00645.18 EGG16365.1 - 9.9e-13 48.8 1.3 9.9e-13 48.8 1.3 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Chorion_2 PF03964.15 EGG16366.1 - 0.05 14.4 2.6 0.09 13.6 2.6 1.4 1 1 0 1 1 1 0 Chorion family 2 SR-25 PF10500.9 EGG16366.1 - 0.059 13.0 8.6 0.086 12.4 8.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ac76 PF05814.11 EGG16366.1 - 0.5 10.4 7.2 0.16 12.0 0.7 2.5 2 0 0 2 2 2 0 Orf76 (Ac76) Baculo_11_kDa PF06143.11 EGG16366.1 - 3.7 7.2 7.8 13 5.5 2.1 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family adh_short PF00106.25 EGG16367.1 - 1.4e-38 132.3 0.0 1.7e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG16367.1 - 5.8e-30 104.6 0.0 8e-30 104.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG16367.1 - 1e-06 28.8 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGG16367.1 - 1.8e-05 24.2 0.0 2.5e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 EGG16367.1 - 0.02 14.7 0.1 0.04 13.8 0.1 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EGG16367.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 EGG16367.1 - 0.2 11.2 0.4 1 8.9 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Ipi1_N PF12333.8 EGG16368.1 - 0.033 14.8 1.2 13 6.4 0.0 2.8 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Ank_3 PF13606.6 EGG16369.1 - 0.056 14.0 0.5 34 5.4 0.0 5.4 5 0 0 5 5 5 0 Ankyrin repeat LZ3wCH PF18517.1 EGG16369.1 - 0.14 12.3 2.1 0.3 11.2 0.6 2.4 2 0 0 2 2 2 0 Leucine zipper with capping helix domain Nucleoside_tran PF01733.18 EGG16369.1 - 0.64 9.3 4.4 1.2 8.5 4.4 1.3 1 0 0 1 1 1 0 Nucleoside transporter LRR_4 PF12799.7 EGG16370.1 - 0.037 14.4 11.6 1.7 9.2 0.2 6.4 5 1 3 8 8 8 0 Leucine Rich repeats (2 copies) EGF_2 PF07974.13 EGG16370.1 - 0.065 13.6 31.5 0.38 11.2 14.2 2.5 2 0 0 2 2 2 0 EGF-like domain Mrr_cat PF04471.12 EGG16371.1 - 2.4e-06 27.6 0.0 4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease NERD PF08378.11 EGG16371.1 - 0.05 14.1 0.0 0.089 13.3 0.0 1.5 1 1 0 1 1 1 0 Nuclease-related domain Ribonucleas_3_3 PF14622.6 EGG16372.1 - 0.021 15.0 0.0 0.057 13.6 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease-III-like Inhibitor_I36 PF03995.13 EGG16372.1 - 0.04 13.8 0.9 0.15 12.0 0.9 2.0 1 0 0 1 1 1 0 Peptidase inhibitor family I36 Glyco_hydro_20 PF00728.22 EGG16373.1 - 3.3e-91 306.3 1.7 4.1e-91 306.0 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGG16373.1 - 4.6e-15 56.5 0.3 4e-13 50.2 0.1 2.7 2 1 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGG16373.1 - 0.00012 22.9 0.2 0.00046 21.0 0.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RTC PF01137.21 EGG16374.1 - 1.4e-78 263.2 0.1 1.8e-78 262.8 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EGG16374.1 - 2e-18 66.8 0.0 5.3e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain BRO1 PF03097.18 EGG16375.1 - 1.5e-109 366.4 13.6 1.5e-109 366.4 13.6 1.8 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EGG16375.1 - 6.2e-71 239.1 16.8 6.2e-71 239.1 16.8 2.8 4 0 0 4 4 4 1 ALIX V-shaped domain binding to HIV DUF2383 PF09537.10 EGG16375.1 - 0.27 11.6 3.9 0.95 9.8 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF2383) DASH_Duo1 PF08651.10 EGG16375.1 - 0.46 10.3 5.9 26 4.7 0.1 4.3 3 0 0 3 3 3 0 DASH complex subunit Duo1 KxDL PF10241.9 EGG16375.1 - 6.1 7.2 15.1 0.065 13.5 1.3 3.9 5 0 0 5 5 5 0 Uncharacterized conserved protein IBR PF01485.21 EGG16376.1 - 4e-07 30.2 3.8 4e-07 30.2 3.8 4.2 5 0 0 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EGG16376.1 - 0.00044 20.5 5.7 0.00044 20.5 5.7 4.0 3 1 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG16376.1 - 0.0033 17.4 5.1 0.0033 17.4 5.1 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG16376.1 - 0.007 16.2 4.8 0.007 16.2 4.8 5.4 6 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG16376.1 - 0.011 15.7 4.9 0.011 15.7 4.9 4.6 3 1 1 4 4 4 0 zinc-RING finger domain Cwf_Cwc_15 PF04889.12 EGG16376.1 - 4.4 7.0 11.7 0.11 12.2 5.1 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BAR_3 PF16746.5 EGG16377.1 - 9.6e-08 32.0 12.4 1.6e-07 31.3 12.4 1.2 1 0 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 EGG16377.1 - 3.5e-07 30.1 12.4 5e-07 29.6 12.4 1.2 1 0 0 1 1 1 1 BAR domain DUF2203 PF09969.9 EGG16377.1 - 4.8 7.9 7.3 1.5 9.6 2.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) AAA_11 PF13086.6 EGG16379.1 - 1.7e-70 237.8 10.3 5.8e-35 121.3 1.0 3.8 3 1 1 4 4 4 2 AAA domain AAA_12 PF13087.6 EGG16379.1 - 2.5e-56 190.4 0.0 7.6e-56 188.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG16379.1 - 8.9e-11 41.9 0.1 0.00027 20.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGG16379.1 - 8.1e-09 36.0 1.3 0.0023 18.3 0.0 3.4 3 1 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EGG16379.1 - 3.2e-07 30.3 0.0 0.013 15.3 0.0 3.6 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EGG16379.1 - 0.00038 19.8 0.1 0.15 11.2 0.0 2.9 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EGG16379.1 - 0.00065 19.8 1.5 0.048 13.7 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGG16379.1 - 0.002 18.4 1.7 0.15 12.4 0.0 3.7 4 1 0 4 4 4 1 AAA domain UvrD-helicase PF00580.21 EGG16379.1 - 0.0022 17.6 5.3 0.23 10.9 0.1 3.2 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain Mg_chelatase PF01078.21 EGG16379.1 - 0.005 16.3 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGG16379.1 - 0.012 16.0 0.0 0.039 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 EGG16379.1 - 0.029 13.8 0.1 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 EGG16379.1 - 0.06 13.8 0.0 0.29 11.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EGG16379.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF572 PF04502.13 EGG16380.1 - 2.6e-57 194.9 16.3 3.5e-57 194.5 16.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Ribosomal_L28 PF00830.19 EGG16381.1 - 4e-18 65.4 1.0 5.9e-18 64.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal L28 family MMR_HSR1 PF01926.23 EGG16382.1 - 9.8e-08 32.1 8.5 5.6e-05 23.2 0.0 3.8 4 1 0 4 4 4 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG16382.1 - 6.2e-07 29.5 3.2 2.8e-06 27.4 0.2 2.8 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGG16382.1 - 0.0018 18.3 2.4 0.0018 18.3 2.4 4.4 2 2 1 3 3 2 1 Dynamin family Roc PF08477.13 EGG16382.1 - 0.0028 17.9 3.5 2.6 8.3 0.0 3.6 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase NOG1 PF06858.14 EGG16382.1 - 0.042 13.6 0.5 0.17 11.7 0.5 2.1 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) ABC_tran PF00005.27 EGG16382.1 - 0.044 14.3 0.0 0.044 14.3 0.0 3.2 3 0 0 3 3 3 0 ABC transporter MobB PF03205.14 EGG16382.1 - 0.079 12.9 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.18 EGG16382.1 - 0.19 11.2 0.1 0.19 11.2 0.1 3.1 4 0 0 4 4 4 0 Ferrous iron transport protein B AAA_22 PF13401.6 EGG16382.1 - 0.27 11.5 1.9 1.7 8.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EGG16382.1 - 0.61 10.6 0.0 0.61 10.6 0.0 3.6 4 1 0 4 4 2 0 AAA domain AAA_17 PF13207.6 EGG16382.1 - 1.6 9.2 6.4 1.3 9.4 0.2 3.1 2 0 0 2 2 2 0 AAA domain ARID PF01388.21 EGG16383.1 - 2.8e-10 40.7 0.2 6.8e-10 39.5 0.2 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain SprA-related PF12118.8 EGG16383.1 - 0.0014 17.9 12.3 0.0014 17.9 12.3 3.2 2 1 1 3 3 3 1 SprA-related family Rhodanese PF00581.20 EGG16386.1 - 8.1e-14 52.0 0.0 1.7e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Tcp11 PF05794.13 EGG16386.1 - 0.019 14.0 0.2 0.34 10.0 0.0 2.4 2 0 0 2 2 2 0 T-complex protein 11 CSS-motif PF12792.7 EGG16386.1 - 0.038 13.5 6.4 0.05 13.1 4.8 1.9 2 0 0 2 2 2 0 CSS motif domain associated with EAL CBM49 PF09478.10 EGG16387.1 - 9.2e-16 57.9 2.8 1.2e-15 57.5 2.8 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 MFS_1 PF07690.16 EGG16389.1 - 0.0014 17.6 7.7 0.0014 17.6 7.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LVIVD PF08309.11 EGG16390.1 - 0.16 11.3 0.2 0.31 10.4 0.2 1.6 1 1 0 1 1 1 0 LVIVD repeat EF-hand_7 PF13499.6 EGG16391.1 - 1.9e-10 41.0 0.0 2.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGG16391.1 - 3.4e-10 38.7 0.4 0.00086 18.7 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGG16391.1 - 3.5e-10 39.6 0.2 4.3e-09 36.1 0.0 1.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGG16391.1 - 5.6e-08 32.1 0.2 0.00054 19.7 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGG16391.1 - 9.5e-05 21.7 0.9 0.0019 17.6 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.6 EGG16391.1 - 0.2 11.5 0.3 1.1 9.1 0.1 2.2 2 1 0 2 2 2 0 EF hand zf-TRAF PF02176.18 EGG16392.1 - 3.2e-13 50.2 24.8 2e-11 44.4 10.9 4.0 2 2 3 5 5 4 2 TRAF-type zinc finger zf-RING_2 PF13639.6 EGG16392.1 - 6.5e-07 29.6 8.4 6.5e-07 29.6 8.4 3.6 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG16392.1 - 8.1e-06 25.6 10.2 8.1e-06 25.6 10.2 3.4 3 1 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG16392.1 - 0.00012 21.9 8.2 0.00012 21.9 8.2 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG16392.1 - 0.0014 18.5 10.5 0.0014 18.5 10.5 3.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Phage_GP20 PF06810.11 EGG16392.1 - 0.0037 17.1 3.0 0.0074 16.1 3.0 1.5 1 0 0 1 1 1 1 Phage minor structural protein GP20 zf-C3HC4_4 PF15227.6 EGG16392.1 - 0.0093 16.1 10.6 0.0093 16.1 10.6 2.9 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGG16392.1 - 0.011 15.7 9.3 0.011 15.7 9.3 3.2 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG16392.1 - 0.014 15.4 10.2 0.014 15.4 10.2 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 EGG16392.1 - 0.019 15.3 7.2 0.019 15.3 7.2 3.7 3 2 0 3 3 3 0 RING-H2 zinc finger domain Molybdop_Fe4S4 PF04879.16 EGG16392.1 - 0.024 14.6 1.4 10 6.2 0.3 2.8 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain zf-TRAF_2 PF15965.5 EGG16392.1 - 0.77 10.3 27.1 0.35 11.4 10.6 3.0 1 1 2 3 3 3 0 TRAF-like zinc-finger zf-TFIIB PF13453.6 EGG16392.1 - 3.4 7.1 12.9 5.2 6.5 2.9 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger ADK_lid PF05191.14 EGG16392.1 - 7.2 6.7 8.3 5.4 7.1 0.3 3.4 3 0 0 3 3 3 0 Adenylate kinase, active site lid Tyr-DNA_phospho PF06087.12 EGG16393.1 - 2.9e-63 214.3 2.0 2.9e-63 214.3 2.0 1.4 2 0 0 2 2 2 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EGG16393.1 - 0.078 12.9 0.4 0.28 11.1 0.1 2.0 2 0 0 2 2 2 0 PLD-like domain B_lectin PF01453.24 EGG16394.1 - 4e-15 56.2 0.7 0.00024 21.6 0.0 4.2 2 2 2 4 4 4 4 D-mannose binding lectin BofC_C PF08955.10 EGG16394.1 - 0.0035 17.4 0.0 19 5.4 0.0 3.8 4 0 0 4 4 4 2 BofC C-terminal domain PAS_3 PF08447.12 EGG16395.1 - 4.3e-16 59.0 0.2 1.1e-15 57.6 0.2 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EGG16395.1 - 7.2e-08 32.6 0.5 1.8e-06 28.2 0.0 2.9 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 EGG16395.1 - 1.1e-06 28.6 3.5 1.2e-06 28.5 0.0 2.9 4 0 0 4 4 4 1 PAS fold PAS_4 PF08448.10 EGG16395.1 - 0.01 16.1 0.1 0.071 13.4 0.0 2.1 2 0 0 2 2 2 0 PAS fold FIN1 PF17300.2 EGG16395.1 - 1.2 8.6 8.1 2.5 7.6 8.1 1.4 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 FKS1_dom1 PF14288.6 EGG16395.1 - 6.4 7.1 8.3 1.1 9.5 2.4 2.7 3 0 0 3 3 3 0 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF1980 PF09323.10 EGG16396.1 - 3.7 7.4 9.5 0.96 9.3 6.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF3430 PF11912.8 EGG16397.1 - 0.0088 16.1 3.5 0.017 15.2 3.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Peptidase_M28 PF04389.17 EGG16398.1 - 5.2e-12 45.9 0.1 1.1e-11 44.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M28 PF04389.17 EGG16399.1 - 4.8e-18 65.6 0.0 5.6e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M28 zf-LYAR PF08790.11 EGG16400.1 - 8.9e-11 41.5 4.8 8.9e-11 41.5 4.8 2.6 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger RNA_pol_Rpb2_6 PF00562.28 EGG16401.1 - 3.7e-109 365.4 0.7 9.6e-109 364.0 0.7 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 EGG16401.1 - 1e-26 92.9 0.0 2e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 EGG16401.1 - 1.1e-19 70.6 0.0 2.9e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EGG16401.1 - 2.4e-17 63.2 0.0 4.2e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EGG16401.1 - 3.3e-17 62.2 0.0 6.2e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_1 PF04563.15 EGG16401.1 - 1.2e-14 54.3 0.0 3.2e-14 52.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_4 PF04566.13 EGG16401.1 - 0.0016 18.7 0.0 0.0039 17.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 Zn_ribbon_recom PF13408.6 EGG16401.1 - 2.4 8.8 3.9 0.92 10.1 0.4 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Acetyltransf_9 PF13527.7 EGG16402.1 - 0.00043 20.4 0.1 0.0028 17.7 0.0 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain CN_hydrolase PF00795.22 EGG16403.1 - 8.2e-38 130.2 0.0 1.3e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EGG16403.1 - 4.8e-26 91.3 0.0 1.3e-25 90.0 0.0 1.5 1 1 0 1 1 1 1 NAD synthase K-box PF01486.17 EGG16405.1 - 0.00031 20.9 10.7 0.00031 20.9 10.7 6.1 3 2 1 4 4 4 2 K-box region ADIP PF11559.8 EGG16405.1 - 0.00064 19.8 18.0 0.00064 19.8 18.0 4.6 2 1 2 4 4 4 1 Afadin- and alpha -actinin-Binding zf-C3HC4_3 PF13920.6 EGG16405.1 - 0.0013 18.5 0.3 0.0022 17.8 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RecR PF02132.15 EGG16405.1 - 0.19 11.4 0.3 0.38 10.3 0.3 1.5 1 0 0 1 1 1 0 RecR protein DUF2716 PF10898.8 EGG16405.1 - 0.37 11.1 4.8 0.16 12.4 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2716) HALZ PF02183.18 EGG16405.1 - 0.62 10.3 56.4 0.11 12.8 1.8 7.1 7 1 0 7 7 7 0 Homeobox associated leucine zipper MAPEG PF01124.18 EGG16406.1 - 2.7e-22 79.0 0.3 3.9e-22 78.5 0.3 1.2 1 0 0 1 1 1 1 MAPEG family Voltage_CLC PF00654.20 EGG16406.1 - 0.0046 16.3 0.4 0.0087 15.3 0.4 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel Esterase_phd PF10503.9 EGG16407.1 - 0.0062 16.1 0.1 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Esterase PHB depolymerase CLASP_N PF12348.8 EGG16408.1 - 2.9e-23 82.6 5.1 9.9e-10 38.4 0.0 5.9 5 0 0 5 5 5 3 CLASP N terminal HEAT PF02985.22 EGG16408.1 - 3.2e-18 64.2 3.4 0.0036 17.4 0.0 10.5 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 EGG16408.1 - 2.6e-10 40.5 0.0 4 7.9 0.0 9.6 9 1 2 11 11 11 1 HEAT repeats Cnd1 PF12717.7 EGG16408.1 - 2.3e-08 34.3 19.3 0.0083 16.2 0.5 7.7 6 3 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGG16408.1 - 0.00047 20.7 0.0 4.2 8.0 0.0 5.4 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGG16408.1 - 0.00068 20.1 7.2 6.3 7.4 0.0 6.6 8 1 0 8 8 7 1 HEAT-like repeat TAF6_C PF07571.13 EGG16408.1 - 0.00081 19.7 0.0 4.1 7.8 0.0 5.4 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain RTP1_C1 PF10363.9 EGG16408.1 - 0.00082 19.5 4.1 6.5 7.0 0.0 6.5 8 0 0 8 8 8 1 Required for nuclear transport of RNA pol II C-terminus 1 IF2_N PF04760.15 EGG16408.1 - 0.028 14.3 0.2 0.67 9.8 0.0 3.2 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region DUF521 PF04412.13 EGG16408.1 - 0.65 8.6 4.7 0.09 11.5 0.1 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF521) TAN PF11640.8 EGG16408.1 - 1.2 9.3 12.3 2.7 8.1 0.0 6.3 8 0 0 8 8 8 0 Telomere-length maintenance and DNA damage repair Sec7_N PF12783.7 EGG16408.1 - 7.1 6.5 13.3 9.6 6.1 2.4 4.3 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Acetyltransf_1 PF00583.25 EGG16409.1 - 2e-05 24.8 0.1 2.9e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG16409.1 - 4.8e-05 23.3 0.1 8.2e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG16409.1 - 0.0019 18.6 0.2 0.0035 17.7 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGG16409.1 - 0.0076 16.4 0.2 0.014 15.5 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGG16409.1 - 0.018 14.7 0.0 0.05 13.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AChE_tetra PF08674.10 EGG16409.1 - 0.073 12.8 0.3 0.15 11.7 0.3 1.5 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain fn3 PF00041.21 EGG16410.1 - 4e-05 23.9 12.1 0.66 10.4 0.2 5.9 6 1 0 6 6 6 2 Fibronectin type III domain EGF_2 PF07974.13 EGG16410.1 - 0.00046 20.5 12.5 0.0012 19.1 12.5 1.8 1 0 0 1 1 1 1 EGF-like domain DUF1573 PF07610.11 EGG16410.1 - 0.027 14.5 1.3 0.25 11.4 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) EB PF01683.18 EGG16410.1 - 0.046 14.0 8.3 0.14 12.4 8.3 1.8 1 0 0 1 1 1 0 EB module OSTbeta PF15048.6 EGG16410.1 - 0.098 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein EGF PF00008.27 EGG16410.1 - 0.12 12.7 8.5 0.54 10.6 8.5 2.2 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EGG16410.1 - 0.15 12.2 6.0 0.44 10.6 6.0 1.8 1 0 0 1 1 1 0 Tenascin EGF domain hEGF PF12661.7 EGG16410.1 - 0.16 12.6 6.6 0.64 10.7 6.6 2.2 1 0 0 1 1 1 0 Human growth factor-like EGF Toxin_ToxA PF11584.8 EGG16410.1 - 0.17 11.9 5.2 0.54 10.3 0.5 3.7 3 0 0 3 3 3 0 Proteinaceous host-selective toxin ToxA I-EGF_1 PF18372.1 EGG16410.1 - 0.24 11.5 7.9 0.61 10.2 7.9 1.8 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Pur_ac_phosph_N PF16656.5 EGG16410.1 - 2.6 8.7 16.2 0.52 10.9 0.8 5.0 5 2 1 6 6 4 0 Purple acid Phosphatase, N-terminal domain CLTH PF10607.9 EGG16412.1 - 2.1e-31 108.8 0.7 4e-31 107.9 0.7 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EGG16412.1 - 1.3e-25 89.8 0.2 2e-25 89.2 0.2 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 EGG16412.1 - 0.00036 20.4 0.0 0.0014 18.5 0.0 2.1 2 0 0 2 2 2 1 LisH DS PF01916.17 EGG16413.1 - 2.2e-130 434.1 0.0 2.5e-130 433.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase GRDB PF07355.12 EGG16413.1 - 0.054 12.7 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) AMP-binding PF00501.28 EGG16414.1 - 4.7e-69 233.0 0.0 6.8e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGG16414.1 - 3.8e-31 108.2 0.0 7e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGG16414.1 - 5.6e-06 26.0 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 EGG16414.1 - 1.1e-05 26.3 0.0 2.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 EGG16414.1 - 1.6e-05 24.0 0.2 2.9e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGG16414.1 - 0.00014 21.1 0.2 0.00024 20.3 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EGG16414.1 - 0.00035 20.1 0.1 0.00061 19.3 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGG16414.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding PP-binding PF00550.25 EGG16414.1 - 0.0029 17.9 0.1 0.0061 16.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Sec7_N PF12783.7 EGG16414.1 - 0.0032 17.4 0.3 0.0096 15.8 0.3 1.8 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal KR PF08659.10 EGG16414.1 - 0.01 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 KR domain NUMOD1 PF07453.13 EGG16414.1 - 0.019 15.2 0.6 0.068 13.5 0.6 2.0 1 0 0 1 1 1 0 NUMOD1 domain SUIM_assoc PF16619.5 EGG16414.1 - 0.025 14.7 1.3 1.7 8.8 0.2 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 adh_short PF00106.25 EGG16414.1 - 0.033 13.7 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 EGG16414.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Ribosomal_L18A PF01775.17 EGG16415.1 - 2.7e-49 166.3 3.5 7e-49 164.9 3.5 1.8 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Urb2 PF10441.9 EGG16415.1 - 4e-12 46.5 0.7 4e-12 46.5 0.7 5.2 5 1 0 5 5 5 1 Urb2/Npa2 family ADD_ATRX PF17981.1 EGG16416.1 - 0.015 15.2 0.4 0.015 15.2 0.4 1.9 2 0 0 2 2 2 0 Cysteine Rich ADD domain VWA_2 PF13519.6 EGG16417.1 - 3.9e-07 30.7 0.0 1.3e-06 29.0 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain EF-hand_8 PF13833.6 EGG16417.1 - 1.1e-05 25.2 0.0 0.00028 20.7 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGG16417.1 - 2.7e-05 23.7 0.0 0.17 11.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain WWE PF02825.20 EGG16417.1 - 2.7e-05 24.6 0.4 7.7e-05 23.2 0.4 1.8 1 0 0 1 1 1 1 WWE domain EF-hand_7 PF13499.6 EGG16417.1 - 0.00012 22.4 0.0 0.00032 21.1 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGG16417.1 - 0.0016 17.9 0.3 0.029 13.9 0.1 2.6 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.13 EGG16417.1 - 0.08 13.0 0.2 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) YL1 PF05764.13 EGG16417.1 - 1.1 9.3 8.7 0.14 12.2 3.1 2.0 2 0 0 2 2 2 0 YL1 nuclear protein Tir_receptor_C PF07489.11 EGG16417.1 - 7.6 6.4 9.1 0.94 9.4 1.0 2.6 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Met_10 PF02475.16 EGG16419.1 - 3e-08 33.6 0.1 5.9e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 EGG16419.1 - 8.3e-07 28.7 0.1 1.2e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGG16419.1 - 1.3e-06 29.1 0.0 2.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG16419.1 - 3.6e-05 23.7 0.1 7.2e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGG16419.1 - 0.00015 21.8 0.1 0.00026 21.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG16419.1 - 0.00017 21.4 0.0 0.00058 19.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG16419.1 - 0.00057 20.5 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG16419.1 - 0.0023 18.6 0.3 0.012 16.3 0.0 2.3 2 1 1 3 3 3 1 Methyltransferase domain MTS PF05175.14 EGG16419.1 - 0.0032 17.0 0.1 0.0049 16.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EGG16419.1 - 0.0056 16.4 0.2 0.015 15.0 0.1 1.7 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_32 PF13679.6 EGG16419.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EGG16419.1 - 0.019 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DREV PF05219.12 EGG16419.1 - 0.083 12.0 0.0 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 DREV methyltransferase FtsJ PF01728.19 EGG16419.1 - 0.084 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 EGG16419.1 - 0.094 13.7 0.0 0.22 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Mito_carr PF00153.27 EGG16420.1 - 2.8e-58 193.8 5.2 1.1e-19 70.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EGG16420.1 - 0.095 12.9 0.0 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase HEAT PF02985.22 EGG16421.1 - 2.7e-06 27.2 0.0 1.5 9.3 0.0 5.4 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.6 EGG16421.1 - 0.014 15.9 0.0 11 6.7 0.0 4.9 5 0 0 5 5 5 0 HEAT-like repeat DKNYY PF13644.6 EGG16421.1 - 0.53 11.1 11.1 1.1 10.0 6.1 3.3 3 0 0 3 3 3 0 DKNYY family ATP12 PF07542.11 EGG16422.1 - 8.3e-27 93.8 0.0 1.5e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein RVT_1 PF00078.27 EGG16423.1 - 3.1e-14 53.0 0.0 6.4e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EGG16423.1 - 0.0036 18.0 0.0 0.011 16.4 0.0 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PS_Dcarbxylase PF02666.15 EGG16425.1 - 5.7e-59 199.0 0.0 8.2e-59 198.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase ThiS PF02597.20 EGG16426.1 - 2.8e-10 40.7 0.0 4.5e-10 40.0 0.0 1.4 1 1 0 1 1 1 1 ThiS family Pkinase PF00069.25 EGG16427.1 - 5.5e-46 157.1 0.1 9.6e-46 156.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16427.1 - 4.4e-26 91.7 0.0 6.9e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGG16427.1 - 0.00022 20.6 0.1 0.00037 19.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGG16427.1 - 0.022 14.1 0.0 0.74 9.1 0.0 2.2 1 1 0 2 2 2 0 Kinase-like DUF1077 PF06417.12 EGG16428.1 - 1.7e-11 44.2 4.8 3.1e-09 36.9 0.1 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF1077) Androgen_recep PF02166.16 EGG16429.1 - 0.022 13.6 1.1 0.036 12.9 1.1 1.3 1 0 0 1 1 1 0 Androgen receptor Mucin PF01456.17 EGG16429.1 - 1.4 8.9 20.1 0.14 12.2 10.5 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein PP1c_bdg PF10488.9 EGG16430.1 - 0.055 13.0 0.0 0.059 12.9 0.0 1.1 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region PHD PF00628.29 EGG16431.1 - 2.6e-06 27.2 7.0 2.6e-06 27.2 7.0 4.0 3 1 1 4 4 4 1 PHD-finger Ago_N_1 PF18351.1 EGG16431.1 - 3.6 8.1 8.8 0.82 10.1 2.3 2.9 3 0 0 3 3 3 0 Fungal Argonaute N-terminal domain Npa1 PF11707.8 EGG16432.1 - 0.098 12.0 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal TPR_1 PF00515.28 EGG16433.1 - 2e-05 24.2 0.3 0.00031 20.4 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG16433.1 - 0.00015 22.0 3.9 0.0014 18.9 0.3 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG16433.1 - 0.0006 19.7 0.4 0.011 15.8 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG16433.1 - 0.0055 16.8 0.6 0.0055 16.8 0.6 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG16433.1 - 0.027 14.5 0.1 22 5.4 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGG16433.1 - 0.12 12.1 0.7 0.47 10.2 0.2 2.3 2 0 0 2 2 2 0 TPR repeat Atrophin-1 PF03154.15 EGG16433.1 - 1.1 7.4 7.3 2.6 6.2 7.3 1.5 1 0 0 1 1 1 0 Atrophin-1 family Preseq_ALAS PF09029.10 EGG16434.1 - 0.13 12.7 3.5 0.22 12.0 0.4 2.2 1 1 1 2 2 2 0 5-aminolevulinate synthase presequence Hamartin PF04388.12 EGG16434.1 - 0.35 9.5 8.4 0.37 9.4 8.4 1.1 1 0 0 1 1 1 0 Hamartin protein Utp12 PF04003.12 EGG16435.1 - 1.8e-13 50.7 1.3 5.1e-13 49.3 0.9 2.0 1 1 1 2 2 2 1 Dip2/Utp12 Family WD40 PF00400.32 EGG16435.1 - 0.14 13.1 0.9 8.9 7.4 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Striatin PF08232.12 EGG16435.1 - 0.59 10.7 8.7 1 9.9 3.4 2.4 2 0 0 2 2 2 0 Striatin family TFIIA PF03153.13 EGG16435.1 - 2 8.3 27.6 3.2 7.7 27.6 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 EGG16435.1 - 6 6.2 22.9 2.4 7.5 13.3 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DCP2 PF05026.13 EGG16436.1 - 0.035 14.4 0.7 0.24 11.8 0.1 2.7 2 0 0 2 2 2 0 Dcp2, box A domain Ank_2 PF12796.7 EGG16436.1 - 0.064 13.8 1.9 23 5.7 0.0 4.7 5 1 1 6 6 6 0 Ankyrin repeats (3 copies) B-block_TFIIIC PF04182.12 EGG16437.1 - 6.3e-16 58.3 2.1 9.7e-15 54.5 0.1 3.9 5 0 0 5 5 5 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 EGG16437.1 - 0.035 13.7 0.1 0.18 11.4 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 EGG16437.1 - 0.09 12.7 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 HTH domain Ribosomal_60s PF00428.19 EGG16437.1 - 0.75 10.4 19.7 2.3 8.8 5.7 3.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein MOR2-PAG1_N PF14222.6 EGG16438.1 - 1.5e-77 261.9 0.9 1.9e-77 261.5 0.9 1.1 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_mid PF14228.6 EGG16439.1 - 2.7e-46 157.8 11.7 2e-32 111.9 4.5 2.0 1 1 1 2 2 2 2 Cell morphogenesis central region DUF4913 PF16259.5 EGG16439.1 - 0.016 15.2 0.0 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) MOR2-PAG1_C PF14225.6 EGG16440.1 - 2.6e-45 155.3 0.3 9.4e-45 153.4 0.1 2.1 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EGG16440.1 - 7.6e-19 66.9 0.0 1.1e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Cell morphogenesis central region TRAF_BIRC3_bd PF16673.5 EGG16440.1 - 0.088 12.6 0.1 0.24 11.2 0.1 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Ank_2 PF12796.7 EGG16441.1 - 6.1e-53 177.3 19.3 2.7e-16 59.9 3.1 5.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16441.1 - 4.1e-42 142.0 3.2 3.7e-12 46.5 0.0 6.5 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EGG16441.1 - 1.8e-39 132.5 18.9 1e-06 28.9 0.2 9.0 10 0 0 10 10 10 7 Ankyrin repeat Ank_3 PF13606.6 EGG16441.1 - 9.6e-38 123.9 8.0 6.9e-05 23.0 0.0 9.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 EGG16441.1 - 3.8e-33 113.1 19.6 1.2e-08 35.1 0.5 8.9 3 1 7 10 10 10 8 Ankyrin repeats (many copies) F-box-like PF12937.7 EGG16441.1 - 2e-08 34.0 0.3 3.4e-08 33.2 0.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG16441.1 - 8.4e-06 25.5 0.6 1.5e-05 24.7 0.6 1.5 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.25 EGG16442.1 - 2.6e-69 233.5 0.0 3.8e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16442.1 - 2.4e-34 118.8 0.0 4.1e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG16442.1 - 0.0001 21.7 0.1 0.00042 19.7 0.1 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGG16442.1 - 0.0018 17.6 0.4 0.0031 16.9 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGG16442.1 - 0.012 14.5 1.9 0.031 13.2 1.9 1.6 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EGG16442.1 - 0.033 13.8 1.1 3.1 7.4 0.0 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGG16442.1 - 0.061 13.2 0.0 3 7.7 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGG16442.1 - 0.11 11.3 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase FeoB_N PF02421.18 EGG16442.1 - 0.21 11.1 0.6 0.83 9.2 0.5 1.7 1 1 1 2 2 2 0 Ferrous iron transport protein B Malate_synthase PF01274.22 EGG16443.1 - 1e-107 360.6 0.0 1.5e-106 356.8 0.0 1.9 1 1 0 1 1 1 1 Malate synthase FAE1_CUT1_RppA PF08392.12 EGG16444.1 - 2.3e-127 424.3 0.0 3.1e-127 423.8 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.15 EGG16444.1 - 9.3e-12 45.2 0.0 1.9e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 EGG16444.1 - 5.8e-11 42.4 0.0 5.2e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Cadherin_C_2 PF16492.5 EGG16444.1 - 0.00065 20.4 0.1 0.0014 19.3 0.1 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal Chal_sti_synt_N PF00195.19 EGG16444.1 - 0.0064 15.9 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.10 EGG16444.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MgtE PF01769.16 EGG16444.1 - 0.024 15.0 0.1 0.047 14.1 0.1 1.4 1 0 0 1 1 1 0 Divalent cation transporter TMEM154 PF15102.6 EGG16444.1 - 0.085 12.8 0.7 12 5.8 0.7 2.3 2 0 0 2 2 2 0 TMEM154 protein family MTS PF05175.14 EGG16444.1 - 0.15 11.6 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain MMR_HSR1 PF01926.23 EGG16445.1 - 8.1e-05 22.7 0.0 0.00045 20.3 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsJ PF01728.19 EGG16445.1 - 0.00026 21.2 0.0 0.0039 17.3 0.0 2.3 2 0 0 2 2 2 1 FtsJ-like methyltransferase AAA_23 PF13476.6 EGG16445.1 - 0.0024 18.4 11.6 0.043 14.3 0.1 3.6 3 0 0 3 3 3 2 AAA domain MeaB PF03308.16 EGG16445.1 - 0.0027 16.7 0.0 0.02 13.9 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 EGG16445.1 - 0.0037 17.0 0.0 0.0087 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain CREPT PF16566.5 EGG16445.1 - 0.017 15.3 2.5 0.11 12.7 0.0 2.7 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour AAA_18 PF13238.6 EGG16445.1 - 0.088 13.3 0.1 0.92 10.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGG16445.1 - 0.23 12.0 4.0 0.81 10.2 0.0 3.1 3 0 0 3 3 3 0 ABC transporter Snf7 PF03357.21 EGG16447.1 - 2.2e-41 141.3 16.8 2.7e-41 141.1 16.8 1.0 1 0 0 1 1 1 1 Snf7 Actin PF00022.19 EGG16447.1 - 0.0028 16.3 1.0 0.0031 16.2 1.0 1.1 1 0 0 1 1 1 1 Actin Hydantoinase_B PF02538.14 EGG16447.1 - 0.0048 15.4 1.3 0.0059 15.1 1.3 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase DUF1664 PF07889.12 EGG16447.1 - 0.026 14.6 9.4 0.061 13.4 3.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2890 PF11081.8 EGG16447.1 - 0.037 14.2 1.3 0.037 14.2 1.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2890) DUF1319 PF07028.11 EGG16447.1 - 0.062 13.5 1.4 0.3 11.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Syntaxin-6_N PF09177.11 EGG16447.1 - 0.12 12.9 3.1 1 10.0 0.3 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Prefoldin PF02996.17 EGG16447.1 - 0.47 10.4 8.0 1.1 9.2 0.0 3.2 2 1 1 3 3 3 0 Prefoldin subunit ELMO_CED12 PF04727.13 EGG16448.1 - 3e-44 151.2 0.1 3e-44 151.2 0.1 1.9 2 0 0 2 2 2 1 ELMO/CED-12 family Ank_2 PF12796.7 EGG16448.1 - 2.9e-13 50.2 3.8 1.5e-05 25.5 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG16448.1 - 6.1e-11 41.6 0.4 0.0074 16.7 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EGG16448.1 - 6.3e-11 42.6 3.2 2.9e-05 24.5 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16448.1 - 8.1e-11 42.0 0.6 2e-05 24.7 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGG16448.1 - 1.8e-10 40.8 2.5 0.0077 16.6 0.1 4.8 3 1 0 3 3 3 3 Ankyrin repeat DUF3361 PF11841.8 EGG16449.1 - 5e-08 33.0 0.1 8.7e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Pkinase PF00069.25 EGG16450.1 - 2.9e-60 203.9 0.0 3.8e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16450.1 - 5.8e-26 91.3 0.0 1.1e-25 90.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG16450.1 - 6.4e-05 22.4 0.0 0.00014 21.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGG16450.1 - 0.0014 18.1 0.2 0.0024 17.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGG16450.1 - 0.031 13.9 0.3 0.081 12.5 0.3 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Velvet PF11754.8 EGG16450.1 - 0.043 13.8 2.8 0.074 13.0 2.8 1.3 1 0 0 1 1 1 0 Velvet factor APH PF01636.23 EGG16450.1 - 0.052 13.5 0.0 0.43 10.5 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGG16450.1 - 0.26 10.0 7.3 0.1 11.3 0.2 2.7 2 1 0 3 3 3 0 Fungal protein kinase F-box-like PF12937.7 EGG16451.1 - 2.9e-09 36.7 0.5 7.4e-09 35.4 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGG16451.1 - 2e-07 30.7 0.3 5.8e-07 29.2 0.3 1.8 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 EGG16451.1 - 0.00019 22.2 2.0 0.0012 19.7 0.1 3.2 2 0 0 2 2 2 1 WD domain, G-beta repeat F-box_4 PF15966.5 EGG16451.1 - 0.0027 17.6 0.1 0.0089 15.9 0.1 1.8 1 0 0 1 1 1 1 F-box Cnd3 PF12719.7 EGG16452.1 - 6.8e-16 58.3 6.6 6.8e-16 58.3 6.6 3.9 5 0 0 5 5 5 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 EGG16452.1 - 1.7e-07 30.9 0.1 0.59 10.6 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 EGG16452.1 - 3e-05 24.1 3.9 0.92 9.5 0.0 4.6 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGG16452.1 - 9.7e-05 22.0 1.7 0.018 14.6 0.1 3.6 3 0 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.6 EGG16452.1 - 0.0018 18.6 0.0 0.47 10.9 0.0 3.6 3 1 1 4 4 4 2 HEAT repeats Vac14_Fab1_bd PF12755.7 EGG16452.1 - 0.0036 17.9 4.4 0.37 11.4 0.2 3.3 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGG16452.1 - 0.038 14.5 0.0 39 4.9 0.0 3.7 4 0 0 4 4 4 0 HEAT-like repeat M16C_assoc PF08367.11 EGG16453.1 - 0.062 12.4 0.2 0.098 11.8 0.2 1.3 1 0 0 1 1 1 0 Peptidase M16C associated Ank_2 PF12796.7 EGG16454.1 - 7.4e-32 109.8 7.1 9.1e-07 29.4 0.0 6.3 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16454.1 - 4.4e-31 106.9 14.5 2.2e-06 28.1 0.1 10.5 6 2 5 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16454.1 - 2.1e-25 88.5 8.5 0.00019 21.7 0.2 12.1 5 2 7 13 13 13 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16454.1 - 3.7e-13 48.3 7.6 0.58 10.9 0.0 12.0 15 1 0 15 15 15 2 Ankyrin repeat Ank PF00023.30 EGG16454.1 - 7.5e-06 26.2 3.1 2.5 8.7 0.0 7.3 5 2 1 6 6 6 1 Ankyrin repeat DUF249 PF03158.13 EGG16454.1 - 0.0026 17.5 9.1 1.7 8.3 0.2 5.2 3 2 3 6 6 6 2 Multigene family 530 protein Ank_4 PF13637.6 EGG16455.1 - 2e-28 98.4 14.3 0.00038 21.0 0.0 11.2 8 4 2 10 10 10 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG16455.1 - 5.7e-27 94.1 8.6 1.7e-05 25.3 0.0 7.0 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG16455.1 - 9.2e-16 57.7 9.1 0.066 13.6 0.0 11.5 6 3 7 13 13 13 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16455.1 - 3.5e-12 45.4 6.2 5.8 7.8 0.0 12.1 15 0 0 15 15 15 2 Ankyrin repeat Ndc80_HEC PF03801.13 EGG16455.1 - 0.0029 17.2 2.0 1.8 8.2 0.0 4.0 4 0 0 4 4 4 1 HEC/Ndc80p family Ank PF00023.30 EGG16455.1 - 0.0077 16.6 0.1 1.2e+02 3.4 0.0 6.7 8 2 1 9 9 9 0 Ankyrin repeat DUF3447 PF11929.8 EGG16455.1 - 0.014 15.3 0.9 0.014 15.3 0.9 5.8 4 3 4 8 8 8 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EGG16457.1 - 1.3e-06 28.8 0.3 0.0001 22.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16457.1 - 0.00033 21.2 0.1 0.044 14.4 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16457.1 - 0.00069 19.9 0.1 5 7.6 0.0 4.1 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16457.1 - 0.0014 19.0 0.0 13 6.8 0.0 5.1 4 1 0 4 4 4 1 Ankyrin repeat B3_4 PF03483.17 EGG16457.1 - 0.037 13.7 0.1 0.068 12.8 0.1 1.4 1 0 0 1 1 1 0 B3/4 domain Ank PF00023.30 EGG16457.1 - 2.3 8.8 6.7 1.5e+02 3.1 2.8 4.2 3 1 0 3 3 3 0 Ankyrin repeat SSP160 PF06933.11 EGG16458.1 - 0.03 12.6 16.1 0.041 12.1 16.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 EGG16458.1 - 0.26 11.3 18.1 0.49 10.4 18.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGG16458.1 - 0.31 11.0 23.9 0.5 10.4 23.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein TMEM154 PF15102.6 EGG16458.1 - 0.81 9.6 7.0 15 5.5 9.5 1.7 2 0 0 2 2 2 0 TMEM154 protein family Med13_C PF06333.12 EGG16458.1 - 1 8.6 5.7 1.6 7.9 5.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain MGC-24 PF05283.11 EGG16458.1 - 1.1 9.7 9.7 2.2 8.8 9.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin KTI12 PF08433.10 EGG16460.1 - 2.2e-92 309.4 0.1 2.4e-92 309.2 0.1 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EGG16460.1 - 3.5e-09 36.9 0.0 1.1e-08 35.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EGG16460.1 - 0.00034 21.1 0.5 0.00098 19.5 0.1 1.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGG16460.1 - 0.0011 19.2 0.1 0.003 17.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGG16460.1 - 0.0015 17.6 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein APS_kinase PF01583.20 EGG16460.1 - 0.0019 18.1 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.22 EGG16460.1 - 0.023 15.1 0.1 0.11 12.9 0.0 2.3 3 1 0 3 3 2 0 RNA helicase Zeta_toxin PF06414.12 EGG16460.1 - 0.029 13.7 0.0 0.23 10.7 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin AAA_18 PF13238.6 EGG16460.1 - 0.03 14.9 0.1 0.079 13.5 0.0 1.8 1 1 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EGG16460.1 - 0.04 13.2 0.1 0.092 12.1 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 EGG16460.1 - 0.046 13.8 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGG16460.1 - 0.055 13.1 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EGG16460.1 - 0.06 12.9 0.0 4.8 6.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EGG16460.1 - 0.063 13.0 0.1 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MutS_I PF01624.20 EGG16460.1 - 0.077 13.2 0.0 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 MutS domain I DFP PF04127.15 EGG16460.1 - 0.084 12.7 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ATPase_2 PF01637.18 EGG16460.1 - 0.09 12.7 0.1 0.39 10.6 0.1 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Hydin_ADK PF17213.3 EGG16460.1 - 0.092 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_31 PF13614.6 EGG16460.1 - 0.11 12.4 0.8 0.25 11.2 0.1 1.9 2 1 1 3 3 3 0 AAA domain Pro_dh PF01619.18 EGG16461.1 - 6.1e-12 45.7 0.0 9.3e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase PAP1 PF08601.10 EGG16461.1 - 0.0009 19.1 6.3 0.0015 18.4 6.3 1.3 1 0 0 1 1 1 1 Transcription factor PAP1 NOZZLE PF08744.10 EGG16461.1 - 0.016 14.7 1.4 0.027 14.0 1.4 1.3 1 0 0 1 1 1 0 Plant transcription factor NOZZLE Mito_fiss_reg PF05308.11 EGG16461.1 - 0.039 14.0 6.6 0.077 13.1 6.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Acyl_transf_3 PF01757.22 EGG16462.1 - 1e-23 84.0 46.0 1.6e-22 80.0 43.3 2.7 3 0 0 3 3 3 2 Acyltransferase family UPF0715 PF17094.5 EGG16462.1 - 0.015 15.8 0.8 0.015 15.8 0.8 4.1 5 0 0 5 5 5 0 Uncharacterised protein family (UPF0715) DUF3671 PF12420.8 EGG16462.1 - 3.4 7.8 8.9 2.5 8.2 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function HgmA PF04209.13 EGG16463.1 - 2.7e-209 695.2 0.0 3.1e-209 695.0 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase PseudoU_synth_2 PF00849.22 EGG16464.1 - 5.6e-15 55.8 0.1 6.4e-14 52.4 0.0 2.6 2 1 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.25 EGG16464.1 - 7.1e-10 38.4 0.8 2.4e-09 36.8 0.3 2.2 1 1 1 2 2 2 1 S4 domain ATP-synt_E PF05680.12 EGG16464.1 - 8.9 6.7 7.4 28 5.1 7.4 1.9 1 0 0 1 1 1 0 ATP synthase E chain FAD-oxidase_C PF02913.19 EGG16465.1 - 2.2e-51 174.9 0.0 4.2e-51 174.0 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGG16465.1 - 7.7e-37 126.1 0.0 1.5e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AdoMet_MTase PF07757.13 EGG16466.1 - 2.6e-39 134.0 0.6 4.8e-39 133.2 0.6 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 EGG16466.1 - 0.00086 19.2 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG16466.1 - 0.034 13.9 0.1 0.4 10.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 EGG16466.1 - 0.048 13.7 0.0 0.048 13.7 0.0 2.8 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGG16466.1 - 0.074 13.8 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGG16466.1 - 0.14 12.8 0.0 0.45 11.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGG16466.1 - 1.4 9.7 8.8 5.4 7.8 0.0 3.8 3 0 0 3 3 3 0 Methyltransferase domain Fe-S_biosyn PF01521.20 EGG16467.1 - 2e-18 66.6 0.0 3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PRC PF05239.16 EGG16467.1 - 0.083 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 PRC-barrel domain Amidase PF01425.21 EGG16468.1 - 3.9e-95 319.5 0.0 7.1e-95 318.6 0.0 1.4 1 1 0 1 1 1 1 Amidase 3H PF02829.14 EGG16468.1 - 0.031 14.6 0.2 0.07 13.4 0.2 1.5 1 0 0 1 1 1 0 3H domain PCI PF01399.27 EGG16469.1 - 2.6e-15 56.8 0.2 2.6e-15 56.8 0.2 2.4 2 0 0 2 2 2 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 EGG16469.1 - 3.1e-05 24.0 0.2 3.1e-05 24.0 0.2 1.9 2 0 0 2 2 2 1 CSN4/RPN5/eIF3a helix turn helix domain MIF4G PF02854.19 EGG16469.1 - 0.001 18.7 2.6 0.0022 17.7 0.6 2.2 2 0 0 2 2 2 1 MIF4G domain RPN7 PF10602.9 EGG16469.1 - 0.0067 16.2 0.6 0.013 15.2 0.6 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 EGG16469.1 - 0.031 14.8 0.2 0.14 12.6 0.1 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat Baculo_p74 PF04583.12 EGG16469.1 - 0.068 12.6 0.4 0.15 11.5 0.4 1.5 1 0 0 1 1 1 0 Baculoviridae p74 conserved region TPR_2 PF07719.17 EGG16469.1 - 1.3 9.3 5.3 0.45 10.8 0.7 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat IQCJ-SCHIP1 PF15157.6 EGG16470.1 - 0.16 11.8 0.8 0.3 10.9 0.8 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Metallophos PF00149.28 EGG16471.1 - 1.4e-40 140.0 0.0 1.8e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGG16471.1 - 4.6e-18 65.4 0.2 9.1e-18 64.4 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF2560 PF10834.8 EGG16472.1 - 0.073 13.3 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) PRKCSH-like PF12999.7 EGG16474.1 - 3e-44 150.9 9.3 3e-44 150.9 9.3 2.7 2 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EGG16474.1 - 1.3e-27 96.4 0.2 4.1e-27 94.8 0.0 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 EGG16474.1 - 1.4e-05 25.2 12.7 0.007 16.6 0.5 2.8 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A SOG2 PF10428.9 EGG16474.1 - 0.0062 15.8 0.4 0.0091 15.2 0.4 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein Tropomodulin PF03250.14 EGG16474.1 - 0.011 15.8 0.1 0.011 15.8 0.1 2.9 2 1 1 3 3 3 0 Tropomodulin PRKCSH PF07915.13 EGG16474.1 - 0.025 15.6 0.3 0.025 15.6 0.3 2.8 2 1 0 2 2 2 0 Glucosidase II beta subunit-like protein ETRAMP PF09716.10 EGG16474.1 - 0.15 12.1 2.0 2.5 8.2 0.3 3.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) ALMT PF11744.8 EGG16474.1 - 0.55 9.0 13.5 0.4 9.4 10.3 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter SID-1_RNA_chan PF13965.6 EGG16474.1 - 0.65 8.3 2.6 7.6 4.8 0.3 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 UPF0242 PF06785.11 EGG16474.1 - 0.73 9.9 23.7 10 6.1 20.6 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RR_TM4-6 PF06459.12 EGG16474.1 - 5.4 6.7 16.9 10 5.8 16.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-C3HC4_2 PF13923.6 EGG16476.1 - 4.7e-08 32.7 10.6 4.7e-08 32.7 10.6 3.5 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG16476.1 - 1e-07 31.7 9.7 1e-07 31.7 9.7 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG16476.1 - 1.1e-07 31.8 11.4 1.1e-07 31.8 11.4 4.0 3 1 0 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG16476.1 - 1.3e-07 31.5 6.7 1.3e-07 31.5 6.7 3.4 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGG16476.1 - 1.9e-07 31.1 11.8 1.9e-07 31.1 11.8 2.7 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EGG16476.1 - 3.3e-07 30.1 6.9 3.3e-07 30.1 6.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG16476.1 - 2.4e-06 27.8 9.6 2.4e-06 27.8 9.6 3.0 2 1 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EGG16476.1 - 0.00089 19.1 8.9 0.00089 19.1 8.9 2.9 2 2 0 2 2 2 1 Prokaryotic RING finger family 4 zf-B_box PF00643.24 EGG16476.1 - 0.0056 16.8 8.8 0.0056 16.8 8.8 3.1 3 1 0 3 3 2 1 B-box zinc finger zf-WRNIP1_ubi PF18279.1 EGG16476.1 - 0.48 11.2 2.3 15 6.5 0.1 2.8 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_10 PF16685.5 EGG16476.1 - 2.7 8.2 20.8 0.089 12.9 5.4 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF4234 PF14018.6 EGG16477.1 - 0.016 15.3 0.0 0.023 14.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) APG17 PF04108.12 EGG16478.1 - 1.5e-10 40.8 13.5 5.5e-07 29.1 0.7 7.5 2 2 3 5 5 5 2 Autophagy protein Apg17 ubiquitin PF00240.23 EGG16478.1 - 0.0011 18.7 0.0 0.0011 18.7 0.0 5.2 5 0 0 5 5 5 1 Ubiquitin family DHR10 PF18595.1 EGG16478.1 - 0.0042 17.1 3.5 0.0042 17.1 3.5 12.7 3 2 8 12 12 12 4 Designed helical repeat protein 10 domain Y_phosphatase3 PF13350.6 EGG16479.1 - 0.12 12.3 2.5 0.31 11.0 2.5 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF2969 PF11184.8 EGG16479.1 - 4 7.9 10.3 2.3 8.7 5.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2969) CH PF00307.31 EGG16480.1 - 7.3e-42 142.0 11.5 1.2e-18 67.3 1.0 5.9 4 0 0 4 4 4 3 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGG16480.1 - 2.1e-05 24.3 3.2 0.0013 18.5 0.2 3.8 3 0 0 3 3 3 1 CAMSAP CH domain ADIP PF11559.8 EGG16480.1 - 0.00031 20.9 24.3 0.00031 20.9 24.3 14.8 6 4 10 16 16 16 3 Afadin- and alpha -actinin-Binding Cep57_MT_bd PF06657.13 EGG16480.1 - 0.0064 16.9 1.3 0.0064 16.9 1.3 14.4 8 4 4 14 14 14 2 Centrosome microtubule-binding domain of Cep57 IRF-2BP1_2 PF11261.8 EGG16480.1 - 0.032 13.8 0.0 0.14 11.7 0.0 2.1 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger Erf4 PF10256.9 EGG16483.1 - 2.8e-27 95.1 0.5 2.8e-27 95.1 0.5 2.1 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family V-SNARE_C PF12352.8 EGG16484.1 - 2.5e-16 59.7 1.1 6.4e-16 58.4 1.1 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EGG16484.1 - 0.00052 19.9 0.5 0.00052 19.9 0.5 2.8 2 1 1 3 3 3 1 Sec20 NPV_P10 PF05531.12 EGG16484.1 - 0.019 15.5 3.6 1.6 9.2 0.4 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Rx_N PF18052.1 EGG16484.1 - 0.023 14.9 4.3 0.9 9.9 0.1 2.7 3 0 0 3 3 3 0 Rx N-terminal domain E2F_TDP PF02319.20 EGG16484.1 - 0.023 14.7 1.1 0.053 13.6 0.8 1.9 1 1 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain SR-25 PF10500.9 EGG16484.1 - 2.2 7.8 12.0 0.19 11.3 4.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase_Tyr PF07714.17 EGG16486.1 - 9.8e-62 208.6 0.0 1.3e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG16486.1 - 2.3e-49 168.2 0.0 3.1e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 EGG16486.1 - 3.9e-16 58.9 0.0 8.2e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 EGG16486.1 - 0.00056 19.0 0.1 0.0043 16.1 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGG16486.1 - 0.00077 19.5 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 EGG16486.1 - 0.019 15.1 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC1 family EF-hand_12 PF17901.1 EGG16486.1 - 0.13 12.8 0.1 0.73 10.3 0.0 2.1 2 0 0 2 2 2 0 EF-hand fold domain CN_hydrolase PF00795.22 EGG16488.1 - 1e-18 67.6 0.0 1.6e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF2024 PF09630.10 EGG16488.1 - 0.033 14.1 0.2 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) Myb_DNA-binding PF00249.31 EGG16489.1 - 7.4e-31 106.1 3.5 5.2e-15 55.4 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG16489.1 - 2.2e-24 85.5 1.6 2.4e-16 59.7 0.2 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EGG16489.1 - 0.82 9.7 10.7 4.8 7.2 0.0 4.1 3 1 1 4 4 4 0 SLIDE Myb_DNA-bind_7 PF15963.5 EGG16489.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.5 4 1 1 5 5 5 0 Myb DNA-binding like Baculo_PP31 PF05311.11 EGG16490.1 - 0.0027 17.3 0.9 0.0032 17.0 0.9 1.2 1 0 0 1 1 1 1 Baculovirus 33KDa late protein (PP31) GAGA_bind PF06217.12 EGG16490.1 - 2.3 8.4 5.7 2.6 8.3 5.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Adap_comp_sub PF00928.21 EGG16491.1 - 4.7e-88 295.0 0.1 6.5e-88 294.5 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGG16491.1 - 9.3e-11 41.8 1.6 1.7e-10 41.0 1.6 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EGG16491.1 - 0.02 14.4 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Med30 PF11315.8 EGG16492.1 - 0.17 12.1 1.2 0.67 10.1 0.3 2.6 2 1 0 2 2 2 0 Mediator complex subunit 30 GHMP_kinases_N PF00288.26 EGG16492.1 - 9.1 6.6 7.3 3.5 7.9 1.0 2.8 2 0 0 2 2 2 0 GHMP kinases N terminal domain NDUFA12 PF05071.16 EGG16493.1 - 2.1e-09 38.1 4.1 1.4e-08 35.4 1.7 2.1 1 1 1 2 2 2 2 NADH ubiquinone oxidoreductase subunit NDUFA12 FhuF PF06276.12 EGG16494.1 - 0.2 12.0 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter TIR_2 PF13676.6 EGG16495.1 - 1.4e-20 74.1 0.6 6.5e-19 68.7 0.1 2.8 2 0 0 2 2 2 1 TIR domain RCC1 PF00415.18 EGG16495.1 - 6e-20 71.6 0.5 7.6e-10 39.3 0.2 3.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG16495.1 - 1.8e-15 56.2 4.7 5.1e-07 29.3 1.0 3.8 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 EGG16495.1 - 2.7e-15 56.7 0.1 1e-11 45.2 0.5 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG16495.1 - 6.8e-15 54.9 0.5 2.4e-09 37.3 0.0 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG16495.1 - 9.5e-11 42.0 0.8 1e-05 26.0 0.0 3.9 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16495.1 - 1.4e-09 37.3 0.6 0.014 15.9 0.0 5.3 5 0 0 5 5 4 2 Ankyrin repeat BRCT PF00533.26 EGG16495.1 - 1.7e-07 31.5 1.7 2e-06 28.1 0.1 3.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGG16495.1 - 1.2e-06 28.8 1.9 2.1e-06 28.0 0.1 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain TIR PF01582.20 EGG16495.1 - 1.4e-05 25.0 0.0 1.4e-05 25.0 0.0 3.0 3 0 0 3 3 2 1 TIR domain Ank PF00023.30 EGG16495.1 - 0.0024 18.2 0.0 0.45 11.1 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat DUF1863 PF08937.11 EGG16495.1 - 0.094 13.0 12.8 0.49 10.7 0.1 4.2 2 2 1 3 3 3 0 MTH538 TIR-like domain (DUF1863) UCMA PF17085.5 EGG16495.1 - 0.1 12.6 8.6 0.29 11.2 8.6 1.7 1 0 0 1 1 1 0 Unique cartilage matrix associated protein Peptidase_S49_N PF08496.10 EGG16495.1 - 1.3 9.0 8.6 2.8 8.0 8.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ATP-synt_E PF05680.12 EGG16495.1 - 5.3 7.4 12.4 17 5.8 12.4 1.9 1 0 0 1 1 1 0 ATP synthase E chain Dicty_CTDC PF00526.18 EGG16496.1 - 2e-08 34.0 30.2 2.1e-05 24.3 3.7 18.6 16 2 0 16 16 16 7 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGG16496.1 - 5.7e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain PIP5K PF01504.18 EGG16497.1 - 6.1e-64 215.9 10.3 6.1e-64 215.9 10.3 3.4 3 1 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase PH PF00169.29 EGG16497.1 - 6.7e-15 55.5 0.1 6.7e-15 55.5 0.1 3.6 4 1 0 4 4 4 1 PH domain BSD PF03909.17 EGG16498.1 - 1.9e-13 50.2 1.2 1.9e-13 50.2 1.2 2.4 2 0 0 2 2 2 1 BSD domain EGF_2 PF07974.13 EGG16498.1 - 0.019 15.3 3.8 0.036 14.4 3.8 1.4 1 0 0 1 1 1 0 EGF-like domain Ctr PF04145.15 EGG16498.1 - 0.27 11.9 4.8 0.87 10.2 0.2 3.1 3 0 0 3 3 3 0 Ctr copper transporter family IBR PF01485.21 EGG16499.1 - 2.6e-19 69.2 41.8 5.6e-13 48.9 1.7 4.9 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain CUE PF02845.16 EGG16499.1 - 3.3e-09 36.3 0.3 6.8e-09 35.3 0.3 1.6 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 EGG16499.1 - 0.00042 20.1 0.1 0.0011 18.8 0.0 1.7 2 0 0 2 2 2 1 UBA-like domain zf-C3HC4 PF00097.25 EGG16499.1 - 0.0066 16.3 10.6 0.0066 16.3 10.6 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG16499.1 - 0.013 15.9 9.9 0.013 15.9 9.9 4.1 3 1 1 4 4 4 0 Ring finger domain zf-RING_UBOX PF13445.6 EGG16499.1 - 0.026 14.6 6.7 0.026 14.6 6.7 3.5 3 1 0 3 3 3 0 RING-type zinc-finger TPR_12 PF13424.6 EGG16500.1 - 1.2e-17 64.0 3.7 2.4e-08 34.1 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGG16500.1 - 5.1e-09 35.7 1.1 0.00029 20.6 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG16500.1 - 2e-07 30.6 1.3 0.33 11.2 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGG16500.1 - 4.7e-07 29.5 0.1 5.1e-05 22.8 0.0 2.6 1 1 1 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 EGG16500.1 - 1.2e-05 24.9 4.5 7.2 6.9 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG16500.1 - 1.5e-05 24.8 5.2 0.33 11.3 0.2 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG16500.1 - 2.4e-05 24.0 0.3 1.3 9.0 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG16500.1 - 0.02 15.4 0.9 23 5.6 0.0 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EGG16500.1 - 0.03 14.4 2.4 0.22 11.6 0.5 3.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 DUF745 PF05335.13 EGG16500.1 - 0.051 13.3 0.5 0.051 13.3 0.5 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF745) RE_BstXI PF09552.10 EGG16500.1 - 0.07 12.3 0.1 0.31 10.2 0.0 1.9 2 0 0 2 2 2 0 BstXI restriction endonuclease Arg_tRNA_synt_N PF03485.16 EGG16500.1 - 0.099 13.2 0.2 0.95 10.1 0.0 2.4 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain MIT PF04212.18 EGG16500.1 - 0.17 11.9 4.5 0.92 9.6 0.2 3.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 EGG16500.1 - 0.4 11.2 2.6 41 4.9 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat HTH_44 PF14641.6 EGG16501.1 - 3.2e-05 24.3 0.6 0.0053 17.2 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 F-box PF00646.33 EGG16501.1 - 0.00028 20.7 0.0 0.3 11.0 0.0 3.1 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.7 EGG16501.1 - 0.078 12.9 0.0 14 5.7 0.0 2.9 2 0 0 2 2 2 0 F-box-like Eco57I PF07669.11 EGG16501.1 - 0.12 12.9 2.3 0.15 12.6 0.4 2.2 2 0 0 2 2 2 0 Eco57I restriction-modification methylase FNIP PF05725.12 EGG16501.1 - 1.7 8.9 23.5 1.5 9.0 0.9 6.0 5 0 0 5 5 5 0 FNIP Repeat NUC153 PF08159.12 EGG16502.1 - 8e-10 38.4 0.3 8e-10 38.4 0.3 4.3 4 0 0 4 4 4 1 NUC153 domain TAFII28 PF04719.14 EGG16503.1 - 0.029 14.5 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region TAFII28 PF04719.14 EGG16504.1 - 0.0055 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 hTAFII28-like protein conserved region PIG-H PF10181.9 EGG16506.1 - 6.1e-18 64.5 1.5 1.4e-17 63.3 1.5 1.6 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component FSA_C PF10479.9 EGG16506.1 - 0.027 12.6 1.4 0.034 12.3 1.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus BRCT PF00533.26 EGG16507.1 - 1.6e-34 118.1 8.3 9.6e-07 29.1 0.0 8.2 8 0 0 8 8 8 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGG16507.1 - 5.3e-33 112.8 9.9 3.2e-13 49.4 0.2 6.1 6 0 0 6 6 6 3 twin BRCT domain BRCT_2 PF16589.5 EGG16507.1 - 2.2e-28 98.5 15.5 4.3e-05 23.8 0.1 8.8 9 0 0 9 9 9 7 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EGG16507.1 - 3.7e-12 46.4 1.3 0.0034 17.6 0.0 7.0 7 0 0 7 7 7 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 EGG16507.1 - 1.7e-10 40.7 0.1 4.1e-05 23.4 0.0 5.0 5 1 0 5 5 5 3 Regulator of Ty1 transposition protein 107 BRCT domain Actino_peptide PF14408.6 EGG16507.1 - 0.45 10.7 0.0 0.45 10.7 0.0 2.9 3 0 0 3 3 3 0 Ribosomally synthesised peptide in actinomycetes Asparaginase_2 PF01112.18 EGG16508.1 - 1.5e-33 116.2 1.1 9.5e-20 70.8 0.1 2.8 2 2 0 2 2 2 2 Asparaginase FAM176 PF14851.6 EGG16509.1 - 0.029 14.1 1.7 0.046 13.4 1.7 1.4 1 0 0 1 1 1 0 FAM176 family Churchill PF06573.11 EGG16509.1 - 0.047 14.0 2.7 0.086 13.2 2.4 1.8 1 1 0 1 1 1 0 Churchill protein PI3K_1B_p101 PF10486.9 EGG16509.1 - 0.082 10.7 5.5 0.097 10.4 5.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Tom22 PF04281.13 EGG16509.1 - 0.78 9.5 5.8 1.4 8.7 1.7 2.2 1 1 1 2 2 2 0 Mitochondrial import receptor subunit Tom22 B_lectin PF01453.24 EGG16510.1 - 2.7e-05 24.6 0.0 0.0069 16.9 0.0 2.2 1 1 1 2 2 2 2 D-mannose binding lectin AbrB-like PF14250.6 EGG16510.1 - 0.029 14.5 0.9 2.1 8.5 0.1 2.6 2 1 1 3 3 3 0 AbrB-like transcriptional regulator PCRF PF03462.18 EGG16511.1 - 8.1e-48 162.9 0.2 2.2e-47 161.4 0.1 1.8 1 1 0 1 1 1 1 PCRF domain RF-1 PF00472.20 EGG16511.1 - 8.2e-31 106.4 3.5 2.1e-30 105.0 3.5 1.7 1 0 0 1 1 1 1 RF-1 domain MitMem_reg PF13012.6 EGG16511.1 - 0.072 13.5 0.8 0.29 11.6 0.8 2.0 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Orf78 PF06024.12 EGG16512.1 - 1.5 9.2 0.0 1.5 9.2 0.0 4.9 5 0 0 5 5 5 0 Orf78 (ac78) PCI PF01399.27 EGG16513.1 - 2e-20 73.2 3.4 3.7e-20 72.4 0.0 3.0 3 0 0 3 3 3 1 PCI domain Rpn3_C PF08375.11 EGG16513.1 - 1.7e-18 66.8 0.3 3.5e-18 65.8 0.3 1.5 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal NAD2 PF18782.1 EGG16513.1 - 0.056 13.6 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 TPR_2 PF07719.17 EGG16513.1 - 0.12 12.5 2.3 0.25 11.6 1.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1617 PF07761.12 EGG16514.1 - 0.68 10.0 4.1 0.96 9.5 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1617) LRR_6 PF13516.6 EGG16514.1 - 1.3 9.3 16.3 11 6.4 0.1 5.8 6 0 0 6 6 6 0 Leucine Rich repeat BRCT PF00533.26 EGG16516.1 - 1.2e-05 25.6 0.4 5.9e-05 23.4 0.4 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGG16516.1 - 4.1e-05 23.9 0.3 0.00027 21.3 0.3 2.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Methyltransf_11 PF08241.12 EGG16517.1 - 4.2e-16 59.4 0.0 7.9e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG16517.1 - 3.8e-12 46.7 0.0 9.7e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG16517.1 - 2.7e-08 34.4 0.1 2e-07 31.7 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG16517.1 - 3.8e-07 30.1 0.0 6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG16517.1 - 5.1e-07 29.6 0.4 5.3e-06 26.3 0.3 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG16517.1 - 3.7e-06 26.5 0.1 2e-05 24.1 0.1 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EGG16517.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 EGG16517.1 - 0.0089 15.0 0.0 0.017 14.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.16 EGG16517.1 - 0.046 12.3 0.0 0.066 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Phage_Gp23 PF10669.9 EGG16517.1 - 3.8 7.9 8.0 3.9 7.8 0.2 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF2046 PF09755.9 EGG16518.1 - 1.2e-23 83.8 42.8 4.2e-23 82.0 31.1 2.4 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) PH PF00169.29 EGG16518.1 - 0.0038 17.7 0.3 0.018 15.5 0.3 2.3 1 1 0 1 1 1 1 PH domain MetW PF07021.12 EGG16518.1 - 0.6 9.7 3.2 1.2 8.7 3.2 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF4410 PF14366.6 EGG16518.1 - 1.8 8.5 6.8 9.4 6.2 6.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4410) Pox_A_type_inc PF04508.12 EGG16518.1 - 3.1 7.8 10.0 19 5.3 0.3 4.9 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat LRR_6 PF13516.6 EGG16519.1 - 7.6e-11 41.2 23.3 0.14 12.3 0.1 9.9 10 0 0 10 10 10 5 Leucine Rich repeat RVT_1 PF00078.27 EGG16520.1 - 3.1e-31 108.6 0.4 5.3e-31 107.9 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EGG16520.1 - 2.1e-16 59.8 0.0 5.1e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 EGG16520.1 - 3.7e-11 43.2 0.0 1.8e-10 41.0 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.26 EGG16520.1 - 4.2e-11 43.1 0.0 1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 EGG16520.1 - 1.9e-08 34.5 0.0 5.5e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 EGG16520.1 - 5.5e-06 26.2 0.1 1.2e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Nup188 PF10487.9 EGG16520.1 - 0.045 11.7 0.0 0.071 11.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 SR-25 PF10500.9 EGG16521.1 - 0.21 11.2 27.6 0.25 10.9 27.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 EGG16521.1 - 0.3 11.7 16.9 0.3 11.6 16.9 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain Chorion_2 PF03964.15 EGG16521.1 - 0.86 10.5 12.3 0.9 10.4 12.3 1.1 1 0 0 1 1 1 0 Chorion family 2 SUZ PF12752.7 EGG16521.1 - 1.4 9.7 7.9 1.9 9.3 7.9 1.4 1 0 0 1 1 1 0 SUZ domain CCDC24 PF15669.5 EGG16521.1 - 2.3 8.0 9.9 2.4 8.0 9.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family NAM-associated PF14303.6 EGG16521.1 - 2.8 8.6 6.9 2.8 8.6 6.9 1.0 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF508 PF04370.12 EGG16521.1 - 3.7 7.3 16.6 4.3 7.1 16.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF4614 PF15391.6 EGG16521.1 - 4.1 7.4 15.0 4 7.4 15.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Lin-8 PF03353.15 EGG16521.1 - 6.6 6.2 6.2 6.5 6.2 6.2 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TRM13 PF05206.14 EGG16524.1 - 3.1e-67 226.9 7.3 3.1e-67 226.9 7.3 2.1 2 0 0 2 2 2 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 EGG16524.1 - 0.00052 19.7 2.6 0.00052 19.7 2.6 2.4 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein FAM176 PF14851.6 EGG16524.1 - 5.2 6.7 9.5 1.4 8.6 1.9 2.5 2 0 0 2 2 2 0 FAM176 family HAGH_C PF16123.5 EGG16525.1 - 4.6e-25 87.9 0.3 2.6e-24 85.5 0.1 2.2 2 0 0 2 2 2 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EGG16525.1 - 4.3e-13 49.7 0.4 1.9e-05 24.8 0.1 2.1 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGG16525.1 - 0.00017 21.2 0.3 0.00069 19.2 0.3 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Gp5_C PF06715.12 EGG16525.1 - 0.035 14.2 0.4 0.11 12.7 0.4 1.9 1 0 0 1 1 1 0 Gp5 C-terminal repeat (3 copies) Lactamase_B_3 PF13483.6 EGG16525.1 - 0.062 13.2 0.3 0.098 12.5 0.3 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pox_P4B PF03292.14 EGG16525.1 - 0.12 10.7 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P4B major core protein Metallophos PF00149.28 EGG16526.1 - 7.1e-17 62.6 1.5 7.1e-17 62.6 1.5 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SapB_1 PF05184.15 EGG16526.1 - 0.0049 16.9 1.4 0.01 15.8 1.4 1.6 1 0 0 1 1 1 1 Saposin-like type B, region 1 Metallophos_2 PF12850.7 EGG16526.1 - 0.052 13.8 0.2 0.55 10.4 0.0 2.5 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain ABC_membrane_2 PF06472.15 EGG16527.1 - 4.4e-84 282.1 0.7 1.1e-83 280.8 0.7 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGG16527.1 - 1.3e-19 71.1 0.0 5.1e-18 65.9 0.0 2.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGG16527.1 - 0.00018 21.1 0.0 0.047 13.1 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbmA_BacA PF05992.12 EGG16527.1 - 0.00018 21.0 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 SbmA/BacA-like family AAA_29 PF13555.6 EGG16527.1 - 0.00039 20.1 0.3 0.001 18.8 0.0 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain ABC_membrane PF00664.23 EGG16527.1 - 0.001 18.8 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 EGG16527.1 - 0.001 18.9 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGG16527.1 - 0.0012 19.4 0.6 0.0062 17.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 EGG16527.1 - 0.014 14.6 0.0 0.24 10.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) YpM PF09144.10 EGG16527.1 - 0.037 14.2 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 Yersinia pseudo-tuberculosis mitogen Adeno_IVa2 PF02456.15 EGG16527.1 - 0.048 12.4 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Sec6 PF06046.13 EGG16527.1 - 0.051 12.0 0.0 0.079 11.3 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec6 AAA_18 PF13238.6 EGG16527.1 - 0.064 13.8 0.0 0.25 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EGG16527.1 - 0.091 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RGS12_usC PF16612.5 EGG16527.1 - 0.099 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 AAA_30 PF13604.6 EGG16527.1 - 0.15 11.8 0.0 0.66 9.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG16527.1 - 0.17 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Pex14_N PF04695.13 EGG16528.1 - 2.8 8.6 20.7 9 6.9 20.7 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 EGG16528.1 - 7.2 5.3 5.6 13 4.4 5.6 1.3 1 0 0 1 1 1 0 Presenilin bZIP_2 PF07716.15 EGG16529.1 - 6.2e-05 23.0 15.4 6.2e-05 23.0 15.4 4.6 4 1 0 5 5 5 1 Basic region leucine zipper bZIP_1 PF00170.21 EGG16529.1 - 0.00036 20.6 12.3 0.00036 20.6 12.3 3.0 2 0 0 2 2 2 1 bZIP transcription factor DUF5473 PF17567.2 EGG16529.1 - 1.2 9.4 10.4 0.27 11.5 6.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5473) FH2 PF02181.23 EGG16530.1 - 1.9e-71 241.1 4.6 1.9e-71 241.1 4.6 2.8 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 EGG16530.1 - 4.7e-34 117.7 8.0 4.7e-34 117.7 8.0 3.3 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 EGG16530.1 - 4.6e-24 85.0 0.4 4.6e-24 85.0 0.4 3.7 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain C1_1 PF00130.22 EGG16530.1 - 1.1e-05 25.2 10.8 2.5e-05 24.1 10.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HEAT_2 PF13646.6 EGG16530.1 - 0.026 14.9 0.0 9.4 6.7 0.0 3.2 3 0 0 3 3 3 0 HEAT repeats Zf_RING PF16744.5 EGG16530.1 - 0.55 10.4 6.4 0.69 10.1 4.9 2.0 2 0 0 2 2 2 0 KIAA1045 RING finger Nop25 PF09805.9 EGG16530.1 - 1 9.8 12.1 0.36 11.3 6.5 2.7 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) C1_2 PF03107.16 EGG16530.1 - 2.1 8.8 9.7 4.6 7.6 9.7 1.6 1 0 0 1 1 1 0 C1 domain DUF1788 PF08747.11 EGG16530.1 - 5.1 7.1 10.3 2 8.4 0.6 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1788) PARP PF00644.20 EGG16531.1 - 3.8e-64 215.9 0.0 3.8e-64 215.9 0.0 2.7 3 1 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGG16531.1 - 3.4e-44 150.2 0.7 3.4e-44 150.2 0.7 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EGG16531.1 - 3.5e-21 75.0 2.0 8.8e-21 73.8 2.0 1.7 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 EGG16531.1 - 3.5e-06 27.3 0.1 1.5e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGG16531.1 - 0.0088 16.4 0.1 0.041 14.3 0.0 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGG16531.1 - 0.0092 15.9 0.1 0.0092 15.9 0.1 2.2 3 0 0 3 3 3 1 twin BRCT domain DUF3439 PF11921.8 EGG16531.1 - 0.72 9.8 3.2 1.7 8.6 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CDC45 PF02724.14 EGG16531.1 - 4.7 5.4 19.5 0.23 9.7 13.6 1.6 1 1 1 2 2 2 0 CDC45-like protein Peroxin-3 PF04882.12 EGG16531.1 - 5.6 5.8 18.7 9 5.2 18.7 1.2 1 0 0 1 1 1 0 Peroxin-3 XYPPX PF02162.17 EGG16532.1 - 0.03 14.1 17.1 0.03 14.1 17.1 6.4 4 1 0 4 4 4 0 XYPPX repeat (two copies) Anti-TRAP PF15777.5 EGG16532.1 - 5.2 7.1 11.7 23 5.1 9.3 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HscB_4_cys PF18256.1 EGG16532.1 - 8.2 6.3 12.3 0.4 10.5 6.5 1.8 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Mad3_BUB1_I_2 PF17014.5 EGG16533.1 - 0.039 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein UIM PF02809.20 EGG16533.1 - 0.09 12.7 0.3 0.09 12.7 0.3 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif Myb_DNA-binding PF00249.31 EGG16534.1 - 0.013 15.7 0.0 0.077 13.2 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGG16534.1 - 0.013 15.8 0.0 0.04 14.3 0.0 1.9 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 EGG16535.1 - 1.5e-22 80.2 0.7 2.7e-21 76.1 0.1 3.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16535.1 - 1.3e-13 50.8 0.1 1.3e-13 50.8 0.1 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Arm PF00514.23 EGG16535.1 - 3.7e-06 26.8 0.3 0.18 11.9 0.0 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGG16535.1 - 2.4e-05 24.2 0.0 1.8 9.0 0.0 4.4 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 EGG16535.1 - 0.00015 22.1 1.5 0.078 13.5 0.0 4.6 6 0 0 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 EGG16535.1 - 0.00032 21.0 0.0 1.2 9.5 0.0 3.8 3 1 0 4 4 3 1 HEAT repeats DUF3361 PF11841.8 EGG16535.1 - 0.014 15.4 6.8 0.038 13.9 0.2 4.5 4 1 0 4 4 4 0 Domain of unknown function (DUF3361) Iron_permease PF04120.12 EGG16535.1 - 0.048 13.4 2.9 0.15 11.9 2.9 1.8 1 0 0 1 1 1 0 Low affinity iron permease NopRA1 PF16201.5 EGG16535.1 - 0.053 13.1 3.8 7.1 6.2 0.0 4.1 4 0 0 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 SelK_SelG PF10961.8 EGG16535.1 - 0.54 10.9 2.4 47 4.7 0.2 3.9 3 0 0 3 3 3 0 Selenoprotein SelK_SelG Totivirus_coat PF05518.11 EGG16535.1 - 3.8 5.4 5.1 7.9 4.4 5.1 1.4 1 0 0 1 1 1 0 Totivirus coat protein Peptidase_A22B PF04258.13 EGG16536.1 - 3.1e-83 279.6 13.7 3.8e-83 279.3 13.7 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EGG16536.1 - 5.1e-05 22.9 15.9 0.00085 18.9 15.9 2.4 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease CBM49 PF09478.10 EGG16537.1 - 3.6e-14 52.8 0.2 6e-14 52.1 0.2 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 MAM PF00629.23 EGG16538.1 - 0.057 13.4 0.7 0.23 11.4 0.4 2.0 2 0 0 2 2 2 0 MAM domain, meprin/A5/mu TFIIF_alpha PF05793.12 EGG16539.1 - 0.11 11.1 25.8 0.13 10.8 25.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Njmu-R1 PF15053.6 EGG16541.1 - 6.5e-25 88.0 9.3 6.5e-25 88.0 9.3 3.6 3 2 0 3 3 3 2 Mjmu-R1-like protein family Methyltransf_2 PF00891.18 EGG16542.1 - 1.1e-30 106.5 0.0 1.7e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain RabGAP-TBC PF00566.18 EGG16542.1 - 1.6e-29 103.1 7.3 1.6e-29 103.1 7.3 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Dimerisation2 PF16864.5 EGG16542.1 - 0.00088 19.2 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain HTH_11 PF08279.12 EGG16542.1 - 0.0022 17.9 0.0 0.0055 16.6 0.0 1.7 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 EGG16542.1 - 0.04 13.9 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 EGG16542.1 - 0.051 13.6 0.2 0.1 12.7 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 EGG16542.1 - 0.063 13.6 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.6 EGG16542.1 - 0.11 12.1 0.1 0.55 9.8 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EGG16542.1 - 0.13 12.1 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PQ-loop PF04193.14 EGG16543.1 - 5e-13 48.6 17.5 9.4e-10 38.1 6.3 4.4 4 2 2 6 6 6 3 PQ loop repeat EI24 PF07264.11 EGG16543.1 - 0.19 12.0 17.0 1.1 9.5 7.7 2.7 2 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) zinc_ribbon_6 PF14599.6 EGG16544.1 - 8.1e-21 73.8 4.4 8.1e-21 73.8 4.4 4.5 3 1 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 EGG16544.1 - 1.8e-19 70.0 23.1 1.8e-19 70.0 23.1 4.3 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EGG16544.1 - 7.5e-10 39.0 5.7 7.5e-10 39.0 5.7 5.4 3 2 2 5 5 5 1 Ring finger domain zf-RING_4 PF14570.6 EGG16544.1 - 0.0019 18.0 3.8 0.0019 18.0 3.8 4.9 4 2 0 4 4 4 1 RING/Ubox like zinc-binding domain CENP-B_dimeris PF09026.10 EGG16544.1 - 0.13 12.7 14.1 0.32 11.4 14.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 EGG16544.1 - 1.4 8.9 8.5 0.33 11.0 5.0 1.7 1 1 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.11 EGG16544.1 - 3.9 5.9 6.6 6.1 5.3 6.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Roughex PF06020.11 EGG16544.1 - 4.8 6.2 7.1 7.4 5.6 7.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Nop14 PF04147.12 EGG16544.1 - 9.5 4.3 9.8 15 3.7 9.8 1.2 1 0 0 1 1 1 0 Nop14-like family PNP_UDP_1 PF01048.20 EGG16545.1 - 4.1e-31 108.0 0.6 4.8e-31 107.8 0.6 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily MCM PF00493.23 EGG16546.1 - 3.8e-67 225.7 0.0 6.5e-67 224.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGG16546.1 - 2.1e-37 127.8 0.1 5e-37 126.6 0.1 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGG16546.1 - 4.9e-20 71.7 0.2 1.7e-19 70.0 0.2 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGG16546.1 - 1.8e-11 44.5 2.2 9.3e-11 42.2 2.2 2.2 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 EGG16546.1 - 9.1e-06 25.7 0.1 4.9e-05 23.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGG16546.1 - 0.00012 21.5 0.1 0.056 12.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGG16546.1 - 0.036 13.9 0.0 0.78 9.6 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGG16546.1 - 0.094 12.4 0.1 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Secretin_N_2 PF07655.13 EGG16547.1 - 0.092 13.3 5.7 0.24 12.0 5.7 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain Ank_2 PF12796.7 EGG16548.1 - 2.6e-35 120.9 14.5 2.5e-08 34.4 0.3 7.9 4 2 5 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG16548.1 - 8.3e-26 89.7 20.5 0.021 15.1 0.1 15.7 5 5 12 18 18 18 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG16548.1 - 6.6e-25 87.2 13.5 0.006 17.1 0.1 12.1 5 4 8 13 13 13 6 Ankyrin repeats (many copies) PAP2 PF01569.21 EGG16548.1 - 1.8e-23 82.8 7.6 1.8e-23 82.8 2.0 2.3 1 1 1 2 2 2 1 PAP2 superfamily Ank_3 PF13606.6 EGG16548.1 - 3e-16 57.9 5.2 0.4 11.4 0.0 14.1 14 1 1 15 15 15 1 Ankyrin repeat DUF5049 PF16468.5 EGG16548.1 - 5e-05 23.1 0.0 34 4.5 0.0 7.8 9 1 1 10 10 10 0 Domain of unknown function (DUF5049) ENTH PF01417.20 EGG16548.1 - 0.003 17.6 1.2 1.7 8.7 0.0 4.5 4 1 0 4 4 4 1 ENTH domain Ank PF00023.30 EGG16548.1 - 0.004 17.5 2.8 50 4.6 0.1 7.6 10 3 0 10 10 10 0 Ankyrin repeat Viral_Hsp90 PF03225.14 EGG16548.1 - 0.036 12.6 0.1 2.9 6.3 0.0 2.7 1 1 0 2 2 2 0 Viral heat shock protein Hsp90 homologue Ank_2 PF12796.7 EGG16549.1 - 5.1e-18 65.4 18.5 4.2e-06 27.2 0.4 8.2 5 2 3 9 9 9 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16549.1 - 4.4e-13 49.5 10.1 0.32 11.6 0.0 8.8 6 2 5 11 11 11 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16549.1 - 1.2e-10 41.4 6.8 6.3 7.3 0.0 9.9 6 4 5 11 11 11 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16549.1 - 1.4e-06 28.1 11.7 23 6.0 0.0 10.5 13 0 0 13 13 13 1 Ankyrin repeat Flu_NS2 PF00601.19 EGG16549.1 - 0.079 13.3 1.9 13 6.2 0.2 2.7 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) DUF1400 PF07176.11 EGG16549.1 - 0.15 12.4 1.6 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) SnoaL_2 PF12680.7 EGG16550.1 - 0.0013 19.3 0.0 0.0015 19.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain MpPF1 PF07668.11 EGG16550.1 - 0.016 14.5 0.6 0.019 14.3 0.6 1.1 1 0 0 1 1 1 0 M penetrans paralogue family 1 DUF4440 PF14534.6 EGG16550.1 - 0.031 14.7 0.0 0.034 14.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF1736 PF08409.11 EGG16551.1 - 4.2e-18 65.1 3.3 4.8e-18 64.9 1.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) TPR_1 PF00515.28 EGG16551.1 - 9.6e-09 34.7 0.2 5.4e-06 26.0 0.0 4.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG16551.1 - 4.9e-07 29.4 0.0 0.00014 21.7 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG16551.1 - 0.00011 22.4 0.0 0.02 15.2 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG16551.1 - 0.00027 20.9 2.3 0.19 12.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG16551.1 - 0.00081 19.3 0.0 0.75 10.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG16551.1 - 0.0011 19.2 0.1 0.0088 16.4 0.0 2.7 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGG16551.1 - 0.0013 18.4 0.2 0.02 14.6 0.0 2.9 2 1 1 3 3 3 1 TPR repeat SNAP PF14938.6 EGG16551.1 - 0.0031 17.0 0.3 4.1 6.8 0.0 3.0 3 0 0 3 3 3 2 Soluble NSF attachment protein, SNAP Holin_SPP1 PF04688.13 EGG16551.1 - 0.085 13.0 1.1 0.69 10.1 0.1 2.5 2 0 0 2 2 2 0 SPP1 phage holin Apis_Csd PF11671.8 EGG16551.1 - 0.53 10.3 5.3 1.7 8.6 5.3 1.9 1 0 0 1 1 1 0 Complementary sex determiner protein Orf78 PF06024.12 EGG16551.1 - 2.6 8.4 12.3 18 5.7 1.2 4.0 4 0 0 4 4 4 0 Orf78 (ac78) VanZ PF04892.12 EGG16551.1 - 3.2 8.4 13.3 13 6.5 2.8 3.1 2 0 0 2 2 2 0 VanZ like family DUF4064 PF13273.6 EGG16551.1 - 7 7.0 15.2 76 3.7 6.9 4.3 2 2 1 3 3 3 0 Protein of unknown function (DUF4064) DUF2207 PF09972.9 EGG16551.1 - 9.7 4.8 10.4 0.084 11.6 0.1 2.6 2 2 0 2 2 1 0 Predicted membrane protein (DUF2207) NIF PF03031.18 EGG16552.1 - 1.7e-55 187.1 0.4 2.2e-55 186.7 0.4 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 EGG16552.1 - 0.12 12.8 0.3 0.8 10.1 0.0 2.0 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase TFIIA PF03153.13 EGG16553.1 - 0.28 11.1 36.0 0.11 12.4 22.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.7 EGG16553.1 - 7.5 4.5 32.7 0.032 12.4 13.1 2.3 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Peptidase_M28 PF04389.17 EGG16554.1 - 8.1e-09 35.5 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 DUF5063 PF16702.5 EGG16554.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) Peptidase_M56 PF05569.11 EGG16555.1 - 3e-05 23.4 1.4 0.0049 16.1 0.1 2.0 1 1 1 2 2 2 2 BlaR1 peptidase M56 DUF5305 PF17231.2 EGG16555.1 - 0.00023 20.6 0.2 0.0079 15.6 0.1 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5305) EphA2_TM PF14575.6 EGG16555.1 - 0.00099 19.9 0.1 0.69 10.8 0.0 2.4 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 EGG16555.1 - 0.001 19.3 8.5 0.19 11.9 2.3 2.1 1 1 0 2 2 2 2 Wnt and FGF inhibitory regulator Trp_oprn_chp PF09534.10 EGG16555.1 - 0.0049 16.7 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM154 PF15102.6 EGG16555.1 - 0.0053 16.7 5.7 0.56 10.1 1.1 2.3 1 1 1 2 2 2 2 TMEM154 protein family DUF4690 PF15756.5 EGG16555.1 - 0.014 16.0 0.6 8.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Small Novel Rich in Cartilage FxsA PF04186.13 EGG16555.1 - 0.017 15.3 1.5 0.65 10.1 0.1 2.1 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein SARAF PF06682.12 EGG16555.1 - 0.021 14.5 0.3 0.9 9.1 0.1 2.0 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4366 PF14283.6 EGG16555.1 - 0.025 14.6 0.3 4.6 7.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) DUF3180 PF11377.8 EGG16555.1 - 0.028 14.6 2.5 0.98 9.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) Pox_A14 PF05767.12 EGG16555.1 - 0.03 14.5 0.3 3.4 7.9 0.1 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 HemY_N PF07219.13 EGG16555.1 - 0.037 14.2 0.4 4.1 7.7 0.1 2.2 2 0 0 2 2 2 0 HemY protein N-terminus DUF4834 PF16118.5 EGG16555.1 - 0.045 14.7 5.3 2.5 9.1 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) Aa_trans PF01490.18 EGG16555.1 - 0.05 12.3 0.2 0.068 11.9 0.2 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein TRP PF06011.12 EGG16555.1 - 0.052 12.3 0.1 5.4 5.6 0.0 2.1 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel Prominin PF05478.11 EGG16555.1 - 0.06 11.3 0.0 0.1 10.5 0.0 1.3 1 0 0 1 1 1 0 Prominin Vpu PF00558.19 EGG16555.1 - 0.061 13.1 4.9 0.52 10.1 0.4 2.3 2 0 0 2 2 2 0 Vpu protein Saf_2TM PF18303.1 EGG16555.1 - 0.071 12.7 0.5 4.6 6.8 0.1 2.1 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Myc_target_1 PF15179.6 EGG16555.1 - 0.079 12.9 3.0 1.2 9.0 0.3 2.3 2 0 0 2 2 2 0 Myc target protein 1 Podoplanin PF05808.11 EGG16555.1 - 0.32 11.1 5.3 0.58 10.3 1.1 2.2 1 1 1 2 2 2 0 Podoplanin CbtB PF09489.10 EGG16555.1 - 0.53 10.4 1.9 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) LapA_dom PF06305.11 EGG16555.1 - 0.64 9.9 8.3 1.6 8.6 0.3 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain ETRAMP PF09716.10 EGG16555.1 - 3.5 7.7 5.8 1.8 8.7 0.5 2.3 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Spindle_Spc25 PF08234.12 EGG16556.1 - 1.4e-13 50.8 0.5 8.2e-13 48.4 0.2 2.6 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Epimerase PF01370.21 EGG16556.1 - 6.1e-11 42.2 0.0 2e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGG16556.1 - 1.2e-09 37.7 0.0 1.6e-08 34.0 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGG16556.1 - 4.6e-08 33.2 0.0 7.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGG16556.1 - 1.2e-07 31.2 0.1 0.025 13.8 0.0 3.4 2 1 1 3 3 3 2 Male sterility protein Myb_DNA-bind_6 PF13921.6 EGG16556.1 - 8.3e-07 29.2 0.1 8.3e-07 29.2 0.1 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain NmrA PF05368.13 EGG16556.1 - 3.9e-06 26.6 0.2 1.1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EGG16556.1 - 3.4e-05 23.4 2.2 4.3e-05 23.1 0.0 2.3 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Myb_DNA-binding PF00249.31 EGG16556.1 - 0.00036 20.6 0.0 0.00098 19.3 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain 3Beta_HSD PF01073.19 EGG16556.1 - 0.0005 19.2 0.0 0.0017 17.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family JAB PF01398.21 EGG16557.1 - 7.7e-34 116.2 0.2 1.3e-33 115.5 0.2 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EGG16557.1 - 1e-23 84.0 2.2 2e-23 83.1 2.2 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EGG16557.1 - 2.6e-05 24.0 0.0 4.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EGG16557.1 - 0.15 12.1 0.7 0.24 11.4 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) SET PF00856.28 EGG16557.1 - 0.19 12.1 0.8 0.35 11.2 0.8 1.6 1 1 0 1 1 1 0 SET domain Glyco_transf_22 PF03901.17 EGG16558.1 - 1.2e-41 143.3 12.7 1e-22 81.0 6.3 2.3 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family Glyco_hyd_101C PF17451.2 EGG16558.1 - 0.02 15.2 0.5 0.02 15.2 0.5 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Zip PF02535.22 EGG16558.1 - 0.054 12.7 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4834 PF16118.5 EGG16558.1 - 0.058 14.4 0.3 0.058 14.4 0.3 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Orf78 PF06024.12 EGG16558.1 - 0.092 13.1 0.5 3.6 7.9 0.1 3.0 2 0 0 2 2 2 0 Orf78 (ac78) DUF2368 PF10166.9 EGG16559.1 - 2e-17 63.0 0.7 2.3e-17 62.8 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) Strep_SA_rep PF06696.11 EGG16559.1 - 0.077 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Streptococcal surface antigen repeat YniB PF14002.6 EGG16559.1 - 0.082 12.7 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 YniB-like protein DUF2756 PF10956.8 EGG16559.1 - 0.094 13.2 5.2 0.15 12.6 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) PI3_PI4_kinase PF00454.27 EGG16560.1 - 7.7e-28 98.0 0.0 1.8e-27 96.8 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Phage_holin_8 PF16931.5 EGG16561.1 - 0.033 14.2 0.5 0.039 13.9 0.5 1.1 1 0 0 1 1 1 0 Putative phage holin TTL PF03133.15 EGG16562.1 - 7.3e-62 209.2 2.3 7.3e-62 209.2 2.3 2.1 1 1 1 2 2 2 1 Tubulin-tyrosine ligase family ATP-grasp_3 PF02655.14 EGG16562.1 - 0.0068 16.5 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EGG16562.1 - 0.012 14.9 1.5 0.049 12.9 0.0 2.6 3 1 0 3 3 3 0 Sugar-transfer associated ATP-grasp AlbA_2 PF04326.14 EGG16562.1 - 0.065 13.6 0.1 0.37 11.1 0.1 2.4 1 0 0 1 1 1 0 Putative DNA-binding domain Musclin PF11037.8 EGG16562.1 - 0.17 11.8 0.4 0.54 10.2 0.4 1.9 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle eIF3_subunit PF08597.10 EGG16562.1 - 0.69 9.8 5.8 0.066 13.1 0.7 1.8 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Bac_globin PF01152.21 EGG16563.1 - 0.042 14.0 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 Bacterial-like globin bZIP_1 PF00170.21 EGG16564.1 - 1.2e-06 28.5 6.3 1.2e-06 28.5 6.3 2.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGG16564.1 - 2.1e-05 24.5 10.2 2.1e-05 24.5 10.2 4.1 6 0 0 6 6 6 1 Basic region leucine zipper Acyl-CoA_dh_N PF02771.16 EGG16565.1 - 1e-27 97.0 0.0 2.1e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EGG16565.1 - 1.1e-26 93.8 0.0 1.9e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGG16565.1 - 7e-23 80.7 0.0 1.2e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGG16565.1 - 4.2e-05 23.8 0.0 7.7e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain GFO_IDH_MocA PF01408.22 EGG16566.1 - 2.5e-21 76.7 0.0 3.9e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGG16566.1 - 3.7e-10 39.8 0.0 3.6e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Mito_fiss_Elm1 PF06258.11 EGG16566.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission ELM1 DDE_Tnp_1_6 PF13751.6 EGG16566.1 - 2.8 8.2 4.6 1.8 8.8 0.2 2.3 2 0 0 2 2 2 0 Transposase DDE domain GpcrRhopsn4 PF10192.9 EGG16567.1 - 1.1e-36 126.6 20.2 1.1e-36 126.6 20.2 1.4 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain DUF485 PF04341.12 EGG16567.1 - 0.55 10.2 17.0 0.72 9.8 0.4 3.9 2 1 1 3 3 3 0 Protein of unknown function, DUF485 DUF2157 PF09925.9 EGG16567.1 - 7.2 6.4 11.3 7 6.4 6.5 2.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) VPS9 PF02204.18 EGG16568.1 - 6e-16 58.6 0.4 2.3e-15 56.7 0.4 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 EGG16568.1 - 4.3e-05 23.3 0.0 4.3e-05 23.3 0.0 3.2 2 2 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Casein PF00363.18 EGG16568.1 - 1.6 9.1 6.9 0.3 11.5 0.5 3.2 3 0 0 3 3 3 0 Casein VPS9 PF02204.18 EGG16569.1 - 4.5e-16 59.0 0.4 4.5e-16 59.0 0.4 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain TPR_22 PF18833.1 EGG16569.1 - 0.14 12.3 1.0 1.3 9.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SipA_VBS PF17985.1 EGG16569.1 - 0.31 11.0 2.9 1.6 8.8 0.7 2.9 2 0 0 2 2 2 0 SipA vinculin binding site Cpn60_TCP1 PF00118.24 EGG16570.1 - 1.8e-148 495.2 0.3 2.1e-148 495.0 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tnp_22_dsRBD PF17490.2 EGG16570.1 - 0.027 14.5 0.1 8.2 6.5 0.0 3.4 2 1 0 3 3 3 0 L1 transposable element dsRBD-like domain Erv26 PF04148.13 EGG16571.1 - 8.2e-41 140.1 22.8 3.9e-40 137.9 22.8 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Proteasome PF00227.26 EGG16572.1 - 8.9e-34 116.6 0.1 1e-33 116.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit His_Phos_1 PF00300.22 EGG16573.1 - 4.3e-26 91.8 0.0 5.3e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) E1-E2_ATPase PF00122.20 EGG16574.1 - 3.2e-21 75.7 0.0 9.3e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGG16574.1 - 4.8e-19 69.5 0.1 1.1e-09 38.9 0.0 3.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG16574.1 - 2.8e-05 24.1 0.0 8.5e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGG16574.1 - 0.00092 19.0 0.6 0.21 11.3 0.1 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase NOZZLE PF08744.10 EGG16574.1 - 0.0027 17.2 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 Plant transcription factor NOZZLE DUF4083 PF13314.6 EGG16574.1 - 5 7.2 9.7 0.26 11.3 1.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Vps51 PF08700.11 EGG16575.1 - 5.6e-08 32.8 1.4 5.6e-08 32.8 1.4 3.8 4 0 0 4 4 4 1 Vps51/Vps67 RhoGAP-FF1 PF16512.5 EGG16575.1 - 4.9 7.9 7.7 5.3 7.8 2.4 3.4 3 0 0 3 3 3 0 p190-A and -B Rho GAPs FF domain UDG PF03167.19 EGG16576.1 - 1.3e-24 86.9 0.0 2.7e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Macoilin PF09726.9 EGG16576.1 - 0.058 12.0 11.7 0.067 11.8 11.7 1.1 1 0 0 1 1 1 0 Macoilin family Mem_trans PF03547.18 EGG16576.1 - 0.3 9.4 1.2 0.33 9.3 1.2 1.2 1 0 0 1 1 1 0 Membrane transport protein BSP_II PF05432.11 EGG16576.1 - 0.36 10.5 32.1 0.52 10.0 32.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SOBP PF15279.6 EGG16576.1 - 0.7 10.4 10.0 1 9.9 10.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PI3K_1B_p101 PF10486.9 EGG16576.1 - 1.1 6.9 18.2 1.7 6.3 18.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SDA1 PF05285.12 EGG16576.1 - 3 7.2 36.3 4.2 6.7 36.3 1.1 1 0 0 1 1 1 0 SDA1 Mucin PF01456.17 EGG16576.1 - 3.2 7.8 12.3 5.1 7.1 12.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Nop14 PF04147.12 EGG16576.1 - 5.9 5.0 35.9 8 4.5 35.9 1.1 1 0 0 1 1 1 0 Nop14-like family Mitofilin PF09731.9 EGG16576.1 - 7.9 5.2 29.2 11 4.7 29.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TipE PF16972.5 EGG16576.1 - 8.4 5.5 12.8 11 5.0 12.8 1.2 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE DUF4554 PF15091.6 EGG16576.1 - 8.8 5.1 13.1 13 4.5 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) GREB1 PF15782.5 EGG16576.1 - 9.5 3.2 17.7 12 2.9 17.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SWIM PF04434.17 EGG16577.1 - 0.0016 18.0 1.7 0.0033 17.1 1.7 1.5 1 0 0 1 1 1 1 SWIM zinc finger AAA_14 PF13173.6 EGG16577.1 - 0.0019 18.2 0.5 0.063 13.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EGG16577.1 - 0.0087 16.2 0.4 0.031 14.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EGG16577.1 - 0.073 13.5 0.0 0.71 10.3 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Aurora-A_bind PF09041.10 EGG16578.1 - 0.05 13.7 0.1 0.061 13.4 0.1 1.2 1 0 0 1 1 1 0 Aurora-A binding BB_PF PF18063.1 EGG16579.1 - 6.2e-28 97.8 1.5 1e-27 97.1 1.5 1.3 1 1 0 1 1 1 1 Beta barrel Pore-forming domain Metallophos PF00149.28 EGG16580.1 - 1.9e-07 31.8 1.8 6e-07 30.2 1.6 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EGG16580.1 - 0.00026 21.5 0.0 0.0005 20.6 0.0 1.4 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoLip_ATPase_C PF16212.5 EGG16580.1 - 0.089 12.5 7.4 0.2 11.4 7.4 1.5 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal DUF2070 PF09843.9 EGG16580.1 - 3.8 5.7 9.8 6.5 4.9 9.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2101 PF09874.9 EGG16580.1 - 4.5 6.9 9.8 7.8 6.1 9.8 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) UEV PF05743.13 EGG16581.1 - 1.1e-28 99.5 1.8 2.2e-28 98.5 1.8 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EGG16581.1 - 3.4e-27 94.2 0.1 8.1e-27 93.0 0.1 1.6 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 EGG16581.1 - 0.0036 16.9 1.9 0.0036 16.9 1.9 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme TFIIA PF03153.13 EGG16581.1 - 0.026 14.6 14.9 0.031 14.3 14.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 EGG16581.1 - 0.026 14.6 0.3 0.042 13.9 0.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3292 PF11696.8 EGG16581.1 - 0.051 11.9 5.5 0.079 11.3 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF1661 PF07877.11 EGG16581.1 - 0.057 13.1 0.4 0.12 12.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) DUF3682 PF12446.8 EGG16581.1 - 0.082 13.4 8.2 0.2 12.1 8.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) MMM1 PF10296.9 EGG16581.1 - 0.98 8.4 8.1 1.4 7.9 8.1 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 DUF4106 PF13388.6 EGG16581.1 - 2.7 7.1 17.8 4 6.6 17.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) EIIBC-GUT_N PF03612.14 EGG16581.1 - 7 6.3 6.9 1.5 8.6 3.6 1.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus RWP-RK PF02042.15 EGG16582.1 - 4.7e-07 29.7 0.1 8.6e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_psq PF05225.16 EGG16582.1 - 0.0064 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_8 PF02954.19 EGG16582.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_23 PF13384.6 EGG16582.1 - 0.098 12.5 0.0 0.28 11.1 0.0 1.8 1 1 1 2 2 2 0 Homeodomain-like domain DUF1712 PF08217.11 EGG16583.1 - 2.8e-64 217.7 14.2 3.1e-53 181.2 5.3 3.0 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) Thioredoxin PF00085.20 EGG16584.1 - 4.6e-64 212.9 2.0 2.1e-31 108.0 0.2 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EGG16584.1 - 3.4e-23 82.4 2.2 6.8e-23 81.4 2.2 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 EGG16584.1 - 1.6e-16 60.5 0.3 2.4e-09 37.0 0.0 2.6 1 1 2 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGG16584.1 - 5.2e-12 46.2 3.7 1.3e-05 25.6 0.1 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGG16584.1 - 3.8e-11 43.2 0.3 0.0016 18.7 0.1 3.6 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 EGG16584.1 - 5.3e-11 42.5 0.2 0.00037 20.4 0.1 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 EGG16584.1 - 1.8e-08 34.4 0.1 0.0056 16.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 EGG16584.1 - 7e-06 25.8 2.2 0.059 13.1 0.1 2.5 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.13 EGG16584.1 - 0.00023 21.3 4.1 0.056 13.6 0.1 3.0 3 0 0 3 3 3 2 ERp29, N-terminal domain DDE_Tnp_1_2 PF13586.6 EGG16584.1 - 0.0059 17.0 0.0 20 5.6 0.0 3.6 3 1 0 3 3 3 0 Transposase DDE domain TraF PF13728.6 EGG16584.1 - 0.0075 16.1 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 EGG16584.1 - 0.01 15.8 2.6 0.36 10.7 0.1 2.6 3 0 0 3 3 3 0 Thioredoxin-like domain F-112 PF09645.10 EGG16584.1 - 0.028 14.5 0.0 0.69 10.0 0.0 2.6 2 0 0 2 2 2 0 F-112 protein Thioredoxin_9 PF14595.6 EGG16584.1 - 0.068 12.9 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin HTH_6 PF01418.17 EGG16584.1 - 0.078 13.0 0.3 29 4.7 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family AA_permease_2 PF13520.6 EGG16584.1 - 0.083 11.7 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Amino acid permease DUF4576 PF15144.6 EGG16584.1 - 0.12 12.3 0.1 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) GARS_C PF02843.16 EGG16584.1 - 0.17 12.2 0.8 1 9.7 0.0 2.5 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain Thioredoxin_4 PF13462.6 EGG16584.1 - 1.5 8.9 6.9 2.3 8.4 0.2 3.0 3 1 0 3 3 3 0 Thioredoxin Glutaredoxin PF00462.24 EGG16584.1 - 5.7 7.3 7.0 29 5.0 0.6 3.5 3 1 0 3 3 3 0 Glutaredoxin Tcf25 PF04910.14 EGG16585.1 - 1.8e-76 257.5 5.6 1.8e-76 257.5 5.6 2.8 2 1 0 2 2 2 1 Transcriptional repressor TCF25 eIF3_subunit PF08597.10 EGG16585.1 - 0.0068 16.4 27.0 0.017 15.1 27.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF4604 PF15377.6 EGG16585.1 - 0.077 13.4 37.2 0.02 15.3 33.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF1512 PF07431.12 EGG16585.1 - 0.15 11.0 0.3 0.25 10.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) Sin_N PF04801.13 EGG16585.1 - 0.45 9.7 34.4 0.028 13.6 26.1 2.3 2 0 0 2 2 2 0 Sin-like protein conserved region Utp14 PF04615.13 EGG16585.1 - 0.97 7.9 37.4 2.2 6.8 37.4 1.6 1 0 0 1 1 1 0 Utp14 protein RNA_polI_A34 PF08208.11 EGG16585.1 - 1.1 9.2 31.0 2.8 8.0 31.0 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 MMU163 PF17119.5 EGG16585.1 - 1.3 8.1 13.9 3.4 6.7 13.9 1.9 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Macoilin PF09726.9 EGG16585.1 - 2 6.9 27.0 3.1 6.2 27.0 1.2 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 EGG16585.1 - 2.5 6.1 23.5 4 5.4 23.5 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Menin PF05053.13 EGG16585.1 - 4.8 5.4 19.9 7.7 4.8 19.9 1.3 1 0 0 1 1 1 0 Menin GREB1 PF15782.5 EGG16585.1 - 6.7 3.7 32.1 8.9 3.3 32.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GAGA_bind PF06217.12 EGG16585.1 - 7 6.8 23.9 2.2 8.5 20.3 1.9 2 0 0 2 2 2 0 GAGA binding protein-like family CDC27 PF09507.10 EGG16586.1 - 0.72 9.2 4.8 1 8.7 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MtN3_slv PF03083.16 EGG16587.1 - 2.3e-30 104.5 10.8 3e-16 59.2 2.5 2.1 1 1 1 2 2 2 2 Sugar efflux transporter for intercellular exchange LAB_N PF07578.11 EGG16587.1 - 0.0012 18.9 5.0 0.022 14.8 0.2 2.7 2 1 0 2 2 2 2 Lipid A Biosynthesis N-terminal domain DUF2645 PF10840.8 EGG16587.1 - 0.63 10.7 6.1 0.75 10.5 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2645) PseudoU_synth_2 PF00849.22 EGG16588.1 - 2.2e-31 109.1 0.0 2.2e-31 109.1 0.0 2.5 2 1 0 2 2 2 1 RNA pseudouridylate synthase SR-25 PF10500.9 EGG16588.1 - 9.6e-05 22.1 14.1 9.6e-05 22.1 14.1 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein GGN PF15685.5 EGG16588.1 - 0.24 10.4 0.1 0.52 9.3 0.0 1.5 2 0 0 2 2 2 0 Gametogenetin Hid1 PF12722.7 EGG16588.1 - 0.32 9.1 13.1 0.53 8.3 13.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LAP1C PF05609.12 EGG16588.1 - 0.45 9.6 18.0 0.75 8.8 18.0 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ndc1_Nup PF09531.10 EGG16588.1 - 1.1 7.9 7.5 1.6 7.3 7.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PA28_beta PF02252.18 EGG16589.1 - 1.8e-50 170.4 2.0 2.7e-50 169.8 2.0 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit DUF5618 PF18498.1 EGG16589.1 - 0.058 13.6 2.1 0.067 13.4 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) MAM33 PF02330.16 EGG16590.1 - 1e-11 45.2 24.1 3.6e-05 23.8 0.1 3.1 2 1 0 2 2 2 2 Mitochondrial glycoprotein FmiP_Thoc5 PF09766.9 EGG16590.1 - 0.00037 19.9 6.3 0.00052 19.4 6.3 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 CDC27 PF09507.10 EGG16590.1 - 0.043 13.2 15.2 0.051 13.0 15.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Peptidase_M61_N PF17899.1 EGG16590.1 - 0.053 13.6 0.1 2.8 8.0 0.1 2.3 2 0 0 2 2 2 0 Peptidase M61 N-terminal domain Nop14 PF04147.12 EGG16590.1 - 0.1 10.8 27.2 0.13 10.5 27.2 1.1 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.8 EGG16590.1 - 0.2 10.4 6.8 0.29 9.9 6.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 EGG16590.1 - 0.31 9.7 6.0 0.35 9.6 6.0 1.2 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 EGG16590.1 - 0.33 10.3 17.4 0.45 9.8 17.4 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 EGG16590.1 - 0.59 9.7 18.8 0.9 9.1 18.8 1.4 1 0 0 1 1 1 0 PPP4R2 RNA_pol_Rpc4 PF05132.14 EGG16590.1 - 1.1 9.6 6.5 1.9 8.9 6.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 SDA1 PF05285.12 EGG16590.1 - 2 7.7 27.3 2.8 7.3 27.3 1.1 1 0 0 1 1 1 0 SDA1 CPSF100_C PF13299.6 EGG16590.1 - 2.7 8.2 9.3 5.6 7.1 9.3 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 EGG16590.1 - 2.9 6.1 18.8 3.9 5.7 18.8 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 EGG16590.1 - 2.9 8.2 21.9 4.8 7.5 21.9 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Sporozoite_P67 PF05642.11 EGG16590.1 - 6.6 4.7 14.3 8.7 4.3 14.3 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen RPN2_C PF18004.1 EGG16590.1 - 9.3 6.1 15.0 18 5.2 15.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Peptidase_S9 PF00326.21 EGG16591.1 - 4.1e-32 111.4 0.0 8.3e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGG16591.1 - 1.1e-07 31.8 0.2 0.00025 20.8 0.3 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG16591.1 - 3.8e-06 26.3 0.0 0.0008 18.7 0.0 2.3 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EGG16591.1 - 0.001 19.0 0.0 0.0023 17.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 EGG16591.1 - 0.0025 17.5 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2920 PF11144.8 EGG16591.1 - 0.014 14.5 0.0 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) BAAT_C PF08840.11 EGG16591.1 - 0.049 13.5 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Mucin PF01456.17 EGG16593.1 - 1.1 9.2 15.2 2.9 7.9 1.9 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4834 PF16118.5 EGG16593.1 - 2.5 9.1 6.2 10 7.2 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Tir_receptor_C PF07489.11 EGG16593.1 - 5.6 6.9 11.4 1.3 8.9 1.9 2.2 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus DUF3439 PF11921.8 EGG16593.1 - 6 6.9 10.1 15 5.6 2.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ribosomal_L29e PF01779.17 EGG16594.1 - 1e-18 67.3 9.5 1.8e-18 66.5 9.5 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family Pkinase PF00069.25 EGG16595.1 - 7e-64 215.7 0.2 1.5e-63 214.7 0.2 1.5 1 1 0 1 1 1 1 Protein kinase domain PH_3 PF14593.6 EGG16595.1 - 2.7e-38 130.3 2.1 8.6e-38 128.6 1.0 2.2 2 0 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.17 EGG16595.1 - 5.4e-35 120.9 0.0 3.9e-26 91.9 0.4 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGG16595.1 - 1.9e-06 27.4 0.3 0.0053 16.1 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 EGG16595.1 - 0.00018 20.6 4.4 0.00018 20.6 4.4 2.0 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGG16595.1 - 0.00035 20.0 0.1 0.00056 19.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGG16595.1 - 0.011 15.4 0.1 0.19 11.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGG16595.1 - 0.032 14.2 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family YukC PF10140.9 EGG16595.1 - 0.057 12.2 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC RIO1 PF01163.22 EGG16595.1 - 0.068 12.8 0.6 0.2 11.2 0.6 1.7 1 1 0 1 1 1 0 RIO1 family PH PF00169.29 EGG16595.1 - 0.18 12.4 0.9 1.1 9.8 0.7 2.5 1 1 1 2 2 2 0 PH domain Pkinase_fungal PF17667.1 EGG16595.1 - 0.71 8.6 6.8 3.2 6.4 6.9 2.1 1 1 0 1 1 1 0 Fungal protein kinase ParBc PF02195.18 EGG16596.1 - 5e-12 45.9 0.0 7.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 ParB-like nuclease domain Phosphorylase PF00343.20 EGG16597.1 - 0 1046.9 0.6 0 1046.7 0.6 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Med4 PF10018.9 EGG16598.1 - 3.5e-26 92.1 1.5 3.5e-26 92.1 1.5 2.9 2 1 1 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF3597 PF12200.8 EGG16598.1 - 0.064 13.8 0.5 0.064 13.8 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3597) IF4E PF01652.18 EGG16599.1 - 5e-40 136.9 0.0 7.5e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HOOK PF05622.12 EGG16600.1 - 1.4e-63 215.2 82.1 2.1e-63 214.6 82.1 1.3 1 0 0 1 1 1 1 HOOK protein Filament PF00038.21 EGG16600.1 - 0.0033 17.0 12.5 0.0033 17.0 12.5 5.7 2 2 2 4 4 4 1 Intermediate filament protein CH PF00307.31 EGG16600.1 - 0.0048 17.1 0.3 0.0048 17.1 0.3 2.8 3 1 0 3 3 3 1 Calponin homology (CH) domain BLOC1_2 PF10046.9 EGG16600.1 - 0.014 15.6 9.6 0.014 15.6 9.6 8.0 3 2 4 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CH_2 PF06294.11 EGG16600.1 - 0.036 14.2 2.7 0.095 12.8 0.3 3.0 3 0 0 3 3 3 0 CH-like domain in sperm protein PSII_Pbs27 PF13326.6 EGG16600.1 - 1.3 9.4 7.8 0.76 10.1 1.4 2.9 2 1 0 2 2 2 0 Photosystem II Pbs27 Peptidase_C39_2 PF13529.6 EGG16601.1 - 5.9e-18 65.8 0.1 4.2e-09 37.1 0.0 2.2 1 1 1 2 2 2 2 Peptidase_C39 like family Peptidase_C70 PF12385.8 EGG16601.1 - 0.009 16.0 0.1 5.4 7.0 0.1 2.4 2 0 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 EGG16601.1 - 0.0091 15.8 0.2 0.04 13.7 0.1 2.0 3 0 0 3 3 3 1 Peptidase C39 family PTP_tm PF18861.1 EGG16602.1 - 0.006 16.6 0.0 0.027 14.5 0.0 2.2 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Peptidase_C97 PF05903.14 EGG16603.1 - 0.011 15.5 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 PPPDE putative peptidase domain YflT PF11181.8 EGG16603.1 - 0.065 13.7 0.5 0.085 13.4 0.5 1.1 1 0 0 1 1 1 0 Heat induced stress protein YflT Peptidase_C48 PF02902.19 EGG16604.1 - 9.4e-11 42.0 0.0 3e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Mucin PF01456.17 EGG16604.1 - 0.00096 19.2 16.8 0.0018 18.3 16.8 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein SprA-related PF12118.8 EGG16604.1 - 1 8.5 15.3 4.8 6.2 15.5 1.9 2 0 0 2 2 2 0 SprA-related family Macoilin PF09726.9 EGG16604.1 - 2.7 6.4 7.7 3.8 6.0 7.7 1.1 1 0 0 1 1 1 0 Macoilin family SSP160 PF06933.11 EGG16604.1 - 3.7 5.6 29.7 5.5 5.1 29.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Integrase_H2C2 PF17921.1 EGG16605.1 - 2.1e-16 59.8 0.3 5.1e-16 58.5 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EGG16605.1 - 3.4e-14 53.1 0.0 8e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EGG16605.1 - 2.9e-11 43.1 0.8 8.8e-11 41.6 0.8 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EGG16605.1 - 0.00074 19.7 0.0 0.0025 18.0 0.0 2.0 1 0 0 1 1 1 1 H2C2 zinc finger DUF3437 PF11919.8 EGG16605.1 - 0.0088 15.9 0.1 0.029 14.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) RCC1 PF00415.18 EGG16606.1 - 1.1e-64 214.9 16.2 2e-15 57.1 0.1 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG16606.1 - 4.5e-41 137.9 43.6 4.5e-10 39.1 1.0 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RabGAP-TBC PF00566.18 EGG16606.1 - 6.8e-41 140.3 5.0 6.8e-41 140.3 5.0 2.7 1 1 1 2 2 2 2 Rab-GTPase-TBC domain Hira PF07569.11 EGG16606.1 - 0.087 12.5 3.9 11 5.7 0.2 4.6 3 2 1 5 5 5 0 TUP1-like enhancer of split Cullin_binding PF03556.15 EGG16608.1 - 3.2e-24 85.7 1.4 6.4e-24 84.7 0.4 1.9 2 0 0 2 2 2 1 Cullin binding WEMBL PF05701.11 EGG16610.1 - 0.00018 20.3 21.9 0.00025 19.9 21.9 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Spc7 PF08317.11 EGG16610.1 - 0.00044 19.2 29.0 0.034 13.0 7.6 2.1 1 1 0 2 2 2 2 Spc7 kinetochore protein ZapB PF06005.12 EGG16610.1 - 0.00062 20.2 32.2 0.077 13.5 3.5 4.1 1 1 0 3 3 3 2 Cell division protein ZapB NUDE_C PF04880.13 EGG16610.1 - 0.001 19.6 9.5 0.001 19.6 9.5 2.8 1 1 2 3 3 3 1 NUDE protein, C-terminal conserved region ZnuA PF01297.17 EGG16610.1 - 0.0012 18.3 1.5 0.0012 18.3 1.5 2.3 2 0 0 2 2 2 1 Zinc-uptake complex component A periplasmic IFT57 PF10498.9 EGG16610.1 - 0.0013 17.8 23.9 0.013 14.5 10.8 2.1 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 GAS PF13851.6 EGG16610.1 - 0.0013 18.1 30.6 0.011 15.2 20.1 2.9 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 EGG16610.1 - 0.0016 18.5 10.8 0.69 10.0 0.3 2.9 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF725 PF05267.12 EGG16610.1 - 0.005 16.8 2.6 0.005 16.8 2.6 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF725) DUF812 PF05667.11 EGG16610.1 - 0.0092 14.9 20.8 0.017 14.1 20.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3584 PF12128.8 EGG16610.1 - 0.015 12.8 20.9 0.022 12.3 20.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TSC22 PF01166.18 EGG16610.1 - 0.017 15.4 0.6 0.017 15.4 0.6 4.2 2 2 4 6 6 5 0 TSC-22/dip/bun family KASH_CCD PF14662.6 EGG16610.1 - 0.02 14.7 29.0 1.2 9.0 20.7 3.0 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 EGG16610.1 - 0.043 13.9 29.7 0.21 11.7 15.8 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 EGG16610.1 - 0.046 13.2 32.1 0.11 11.9 15.9 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF5082 PF16888.5 EGG16610.1 - 0.14 12.4 22.1 0.09 13.1 10.5 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) CEP63 PF17045.5 EGG16610.1 - 0.21 11.4 30.7 0.05 13.5 12.2 2.7 1 1 2 3 3 3 0 Centrosomal protein of 63 kDa Lebercilin PF15619.6 EGG16610.1 - 0.24 11.0 30.9 0.38 10.4 17.6 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ERM PF00769.19 EGG16610.1 - 0.29 10.9 28.1 0.31 10.8 13.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family SKA2 PF16740.5 EGG16610.1 - 0.3 10.9 17.5 0.12 12.1 7.3 2.9 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 APG6_N PF17675.1 EGG16610.1 - 0.32 11.5 34.8 4.8 7.7 26.8 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region WXG100 PF06013.12 EGG16610.1 - 0.34 11.2 8.6 0.72 10.1 0.2 3.7 1 1 1 3 3 3 0 Proteins of 100 residues with WXG FUSC PF04632.12 EGG16610.1 - 0.4 9.2 4.2 0.58 8.6 3.8 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family ACCA PF03255.14 EGG16610.1 - 0.43 10.5 17.5 2.1 8.2 6.1 2.5 1 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CALCOCO1 PF07888.11 EGG16610.1 - 0.5 9.2 25.7 0.65 8.8 25.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CdvA PF18822.1 EGG16610.1 - 0.59 10.0 19.6 0.31 10.9 3.1 3.8 1 1 3 4 4 4 0 CdvA-like coiled-coil domain Bacillus_HBL PF05791.11 EGG16610.1 - 0.6 9.9 13.5 0.25 11.1 5.9 2.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) OmpH PF03938.14 EGG16610.1 - 0.69 10.3 27.0 35 4.7 15.7 3.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) YabA PF06156.13 EGG16610.1 - 0.69 10.6 23.4 3.2 8.4 8.4 3.4 1 1 3 4 4 4 0 Initiation control protein YabA ALMT PF11744.8 EGG16610.1 - 0.76 8.5 10.1 0.97 8.2 10.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter HMMR_N PF15905.5 EGG16610.1 - 0.85 9.0 31.9 1.8 8.0 16.9 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FapA PF03961.13 EGG16610.1 - 0.97 8.0 23.1 0.2 10.2 5.8 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A ADIP PF11559.8 EGG16610.1 - 1.1 9.3 25.7 1.4 9.0 7.5 2.7 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 EGG16610.1 - 1.1 8.4 20.4 2.4 7.3 8.0 2.3 1 1 1 2 2 2 0 TMPIT-like protein Fez1 PF06818.15 EGG16610.1 - 1.1 9.6 26.7 43 4.5 27.2 2.1 1 1 1 2 2 2 0 Fez1 ApoO PF09769.9 EGG16610.1 - 1.2 9.1 4.6 12 5.9 0.6 3.0 1 1 1 2 2 2 0 Apolipoprotein O FAM76 PF16046.5 EGG16610.1 - 1.7 7.9 22.8 2.3 7.5 4.4 2.2 1 1 1 2 2 2 0 FAM76 protein DUF1664 PF07889.12 EGG16610.1 - 2.1 8.4 19.7 1.8 8.6 3.6 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 EGG16610.1 - 2.2 8.7 21.8 12 6.3 11.5 3.2 1 1 1 2 2 2 0 Syntaxin-like protein DUF948 PF06103.11 EGG16610.1 - 2.8 8.3 8.2 28 5.0 0.8 3.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.8 EGG16610.1 - 2.8 7.2 23.1 6.3 6.0 11.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EGG16610.1 - 3.1 8.0 22.8 1.4 9.1 10.6 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Med10 PF09748.9 EGG16610.1 - 3.4 7.6 10.7 2.6 8.0 0.7 3.0 1 1 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex ATP-synt_B PF00430.18 EGG16610.1 - 3.5 7.7 15.1 3.5 7.7 1.1 2.8 2 1 1 3 3 3 0 ATP synthase B/B' CF(0) Cluap1 PF10234.9 EGG16610.1 - 3.5 6.9 23.8 3.2 7.1 9.9 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 Zein-binding PF04576.15 EGG16610.1 - 3.5 8.0 20.8 5.9 7.2 9.9 2.6 1 1 1 2 2 2 0 Zein-binding YtxH PF12732.7 EGG16610.1 - 4.1 8.0 9.8 1.4e+03 -0.1 9.7 3.2 1 1 0 1 1 1 0 YtxH-like protein DLP_helical PF18709.1 EGG16610.1 - 4.2 6.5 18.0 0.37 10.0 7.7 2.3 1 1 1 2 2 2 0 Dynamin-like helical domain Spectrin PF00435.21 EGG16610.1 - 4.4 7.9 22.5 24 5.5 10.7 3.0 1 1 1 2 2 2 0 Spectrin repeat UPF0449 PF15136.6 EGG16610.1 - 4.6 7.8 22.9 7.8 7.0 6.0 3.2 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 NPV_P10 PF05531.12 EGG16610.1 - 4.7 7.7 17.3 1.3 9.5 1.9 4.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Jnk-SapK_ap_N PF09744.9 EGG16610.1 - 4.9 7.4 32.1 1.4 9.2 11.2 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 EGG16610.1 - 5.3 6.3 17.3 40 3.4 17.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EGG16610.1 - 5.5 7.0 32.2 1.8e+04 -6.0 32.2 3.0 1 1 0 1 1 0 0 Uncharacterised protein family (UPF0242) N-terminus DMPK_coil PF08826.10 EGG16610.1 - 5.9 7.1 23.2 2.3 8.4 7.6 3.7 2 2 1 3 3 3 0 DMPK coiled coil domain like DUF3683 PF12447.8 EGG16610.1 - 6 7.0 8.5 3.3 7.9 2.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3683) CENP-H PF05837.12 EGG16610.1 - 6 7.3 24.9 0.89 10.0 4.5 3.1 1 1 1 2 2 1 0 Centromere protein H (CENP-H) Exonuc_VII_L PF02601.15 EGG16610.1 - 6.8 6.2 20.2 55 3.2 20.2 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF724 PF05266.14 EGG16610.1 - 6.9 6.5 26.3 5 6.9 11.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 EGG16610.1 - 7.4 6.6 32.1 2.1 8.4 19.7 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 XhlA PF10779.9 EGG16610.1 - 8.7 6.6 22.8 8.9 6.6 0.6 4.3 1 1 2 4 4 4 0 Haemolysin XhlA CREPT PF16566.5 EGG16610.1 - 8.8 6.5 22.2 3.2 7.9 5.1 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Peptidase_S28 PF05577.12 EGG16611.1 - 5.1e-95 318.8 5.6 6e-95 318.6 5.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 LIM PF00412.22 EGG16612.1 - 1.4e-06 28.4 2.1 1.4e-06 28.4 2.1 2.5 2 1 0 2 2 2 1 LIM domain Zn_Tnp_IS1595 PF12760.7 EGG16612.1 - 6 6.9 7.2 1.3 9.1 0.3 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Cytochrom_B558a PF05038.13 EGG16613.1 - 2.6e-08 33.7 9.2 1e-06 28.5 0.4 2.0 1 1 1 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit RskA PF10099.9 EGG16614.1 - 0.00035 20.9 1.4 0.00073 19.9 1.4 1.5 1 0 0 1 1 1 1 Anti-sigma-K factor rskA MCU PF04678.13 EGG16614.1 - 0.2 11.7 3.6 0.11 12.5 0.8 1.9 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Insulin PF00049.18 EGG16614.1 - 2.8 9.0 6.6 8.2 7.5 0.0 3.1 3 0 0 3 3 3 0 Insulin/IGF/Relaxin family G-alpha PF00503.20 EGG16615.1 - 1.7e-83 280.8 1.0 2.2e-83 280.3 1.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGG16615.1 - 1.1e-10 41.2 0.3 2.2e-07 30.5 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG16615.1 - 0.00079 18.8 0.1 0.18 11.1 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGG16615.1 - 0.001 19.2 0.1 2.4 8.4 0.0 3.0 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase CPT PF07931.12 EGG16615.1 - 0.14 12.0 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF639 PF04842.12 EGG16617.1 - 0.0063 16.0 0.6 0.0076 15.7 0.6 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) DUF5118 PF17162.4 EGG16617.1 - 0.046 13.5 0.1 0.094 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) Acetyltransf_2 PF00797.17 EGG16618.1 - 2.7e-19 69.9 0.0 3.1e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Myotub-related PF06602.14 EGG16619.1 - 4.3e-134 446.9 4.7 1.1e-133 445.6 4.7 1.7 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PX PF00787.24 EGG16619.1 - 8.4e-15 54.7 0.6 3.9e-14 52.6 0.6 2.2 1 0 0 1 1 1 1 PX domain Y_phosphatase3 PF13350.6 EGG16619.1 - 0.00031 20.8 0.2 0.0009 19.3 0.1 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family SRP_SPB PF02978.19 EGG16620.1 - 0.00016 22.2 3.8 0.00016 22.2 3.8 2.5 2 1 0 2 2 2 1 Signal peptide binding domain TFIIA PF03153.13 EGG16620.1 - 0.37 10.7 15.1 0.43 10.5 15.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CNOT1_TTP_bind PF16417.5 EGG16620.1 - 0.87 8.7 12.7 0.43 9.7 10.5 1.5 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Neur_chan_memb PF02932.16 EGG16620.1 - 5.5 7.0 6.3 9.4 6.2 6.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Prp18 PF02840.15 EGG16620.1 - 6.7 6.7 8.8 7.9 6.5 5.1 2.3 1 1 0 2 2 2 0 Prp18 domain DUF4770 PF15994.5 EGG16620.1 - 8.8 6.5 14.3 2.9 8.1 10.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) RRM_1 PF00076.22 EGG16621.1 - 2e-10 40.3 0.6 2.5e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG16621.1 - 0.00087 19.2 0.4 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif SUIM_assoc PF16619.5 EGG16621.1 - 0.0055 16.7 4.9 0.0055 16.7 4.9 8.7 4 2 1 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 Otopetrin PF03189.13 EGG16621.1 - 1 8.1 4.8 49 2.5 4.8 3.0 1 1 0 1 1 1 0 Otopetrin Ras PF00071.22 EGG16622.1 - 1.2e-52 177.7 0.1 1.6e-52 177.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG16622.1 - 2.9e-32 111.4 0.0 5.3e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG16622.1 - 1.6e-11 44.0 0.0 2.7e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG16622.1 - 1.7e-06 28.1 0.1 4.1e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGG16622.1 - 2.2e-06 27.2 1.0 5.2e-06 26.0 1.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EGG16622.1 - 1.3e-05 25.2 1.6 6.8e-05 22.8 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EGG16622.1 - 9.8e-05 22.3 1.0 0.008 16.1 0.3 2.9 2 1 1 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EGG16622.1 - 0.0026 18.0 0.0 0.0062 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EGG16622.1 - 0.0048 16.5 0.1 0.063 12.8 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGG16622.1 - 0.0059 16.4 0.4 0.036 13.8 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EGG16622.1 - 0.006 17.0 0.1 0.015 15.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EGG16622.1 - 0.012 15.4 0.0 0.016 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 EGG16622.1 - 0.015 14.5 0.2 0.027 13.6 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.6 EGG16622.1 - 0.017 15.1 0.1 0.037 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGG16622.1 - 0.018 15.2 0.0 0.03 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 EGG16622.1 - 0.019 14.2 2.8 0.19 10.8 0.4 2.4 2 1 1 3 3 3 0 G-protein alpha subunit Septin PF00735.18 EGG16622.1 - 0.028 13.7 1.6 0.054 12.8 0.0 2.1 2 1 1 3 3 3 0 Septin FAM216B PF15107.6 EGG16622.1 - 0.044 13.7 0.3 0.1 12.5 0.3 1.7 1 0 0 1 1 1 0 FAM216B protein family Sigma54_activat PF00158.26 EGG16622.1 - 0.052 13.3 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.19 EGG16622.1 - 0.052 13.1 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EGG16622.1 - 0.08 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EGG16622.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EGG16622.1 - 0.14 11.7 0.1 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGG16622.1 - 0.16 12.4 0.6 0.25 11.8 0.6 1.7 1 1 0 1 1 1 0 ABC transporter DUF3682 PF12446.8 EGG16623.1 - 0.65 10.5 24.2 4.9 7.6 5.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) MerC PF03203.14 EGG16624.1 - 0.064 13.7 1.0 0.26 11.7 0.3 1.9 1 1 1 2 2 2 0 MerC mercury resistance protein Tmemb_14 PF03647.13 EGG16624.1 - 0.084 13.6 7.9 0.13 13.0 7.9 1.2 1 0 0 1 1 1 0 Transmembrane proteins 14C Pex2_Pex12 PF04757.14 EGG16624.1 - 1.1 8.9 5.5 1.2 8.7 2.8 2.0 2 1 0 2 2 2 0 Pex2 / Pex12 amino terminal region CDO_I PF05995.12 EGG16625.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Cysteine dioxygenase type I Snurportin1 PF11538.8 EGG16626.1 - 0.0018 18.4 0.8 0.0018 18.4 0.8 2.3 2 1 0 2 2 2 1 Snurportin1 YscO-like PF16789.5 EGG16626.1 - 0.04 13.9 14.3 0.068 13.2 14.3 1.3 1 0 0 1 1 1 0 YscO-like protein Connexin PF00029.19 EGG16626.1 - 0.053 13.3 4.1 0.46 10.2 2.0 2.4 2 0 0 2 2 2 0 Connexin CDC45 PF02724.14 EGG16626.1 - 7.7 4.7 15.1 3.5 5.8 11.1 2.1 2 0 0 2 2 2 0 CDC45-like protein GDI PF00996.18 EGG16627.1 - 2.1e-211 702.0 0.1 2.5e-211 701.8 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 EGG16627.1 - 1.8e-05 24.2 0.0 2.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pkinase_Tyr PF07714.17 EGG16628.1 - 9.6e-55 185.7 0.0 1.3e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG16628.1 - 3.5e-53 180.6 0.0 5e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EGG16628.1 - 0.00015 21.2 0.1 0.00026 20.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGG16628.1 - 0.016 14.0 0.0 0.016 14.0 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGG16628.1 - 0.052 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL p450 PF00067.22 EGG16629.1 - 3.7e-37 128.2 0.9 2.8e-36 125.3 0.9 1.9 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_14 PF03421.16 EGG16629.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase Herpes_capsid PF06112.11 EGG16629.1 - 0.24 11.4 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein p450 PF00067.22 EGG16630.1 - 1.7e-09 37.0 0.0 1.8e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MTBP_mid PF14919.6 EGG16630.1 - 0.049 12.8 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 MDM2-binding MRP-S33 PF08293.11 EGG16631.1 - 6.5e-08 32.7 1.6 2.5e-07 30.9 1.6 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 SNARE PF05739.19 EGG16632.1 - 0.28 11.2 0.1 0.28 11.2 0.1 1.7 2 0 0 2 2 2 0 SNARE domain G-patch_2 PF12656.7 EGG16633.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 G-patch domain Pkinase_Tyr PF07714.17 EGG16634.1 - 1.8e-58 197.8 0.0 3.1e-58 197.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG16634.1 - 2.8e-51 174.4 0.0 4.8e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Filamin PF00630.19 EGG16634.1 - 8.9e-06 26.5 0.1 0.00038 21.2 0.0 2.9 2 0 0 2 2 2 1 Filamin/ABP280 repeat Pkinase_fungal PF17667.1 EGG16634.1 - 0.00031 19.7 0.3 0.00031 19.7 0.3 2.1 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 EGG16634.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGG16634.1 - 0.24 11.3 0.4 0.38 10.6 0.4 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltr_RsmB-F PF01189.17 EGG16635.1 - 2.1e-37 128.7 0.0 4.7e-36 124.3 0.0 2.5 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Menin PF05053.13 EGG16635.1 - 7.8 4.7 6.9 0.53 8.6 1.4 1.7 2 0 0 2 2 2 0 Menin eIF-5_eIF-2B PF01873.17 EGG16636.1 - 5.9e-38 129.4 1.7 1.9e-37 127.7 1.7 1.8 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Arc_trans_TRASH PF08394.10 EGG16636.1 - 0.028 14.8 2.2 0.028 14.8 2.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain TF_Zn_Ribbon PF08271.12 EGG16636.1 - 0.041 13.4 1.6 0.1 12.1 1.6 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding Peptidase_S64 PF08192.11 EGG16636.1 - 0.81 8.1 13.0 0.99 7.8 13.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 EGG16636.1 - 0.97 6.5 15.3 1.3 6.1 15.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mitofilin PF09731.9 EGG16636.1 - 1.5 7.6 23.6 1.9 7.3 23.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Presenilin PF01080.17 EGG16636.1 - 2 7.1 16.3 2.7 6.7 16.3 1.2 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 EGG16636.1 - 2.8 7.8 26.4 4.9 7.0 26.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TAF4 PF05236.14 EGG16636.1 - 3 7.5 20.3 4.3 7.0 20.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Ndc1_Nup PF09531.10 EGG16636.1 - 3.6 6.2 8.7 4.3 5.9 8.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SLC12 PF03522.15 EGG16636.1 - 4.3 6.3 14.1 5.8 5.8 14.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 EGG16636.1 - 5.4 5.5 15.3 6.3 5.2 15.3 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EGG16636.1 - 7 5.4 15.3 8.5 5.1 15.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pinin_SDK_memA PF04696.13 EGG16637.1 - 1.2e-18 67.4 12.2 1.2e-18 67.4 12.2 3.4 4 0 0 4 4 4 1 pinin/SDK/memA/ protein conserved region TPR_2 PF07719.17 EGG16638.1 - 5e-17 60.6 0.6 0.00045 20.1 0.1 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGG16638.1 - 1.5e-14 53.1 8.2 0.0013 18.5 0.1 6.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGG16638.1 - 9.9e-10 38.6 2.7 0.063 13.6 0.0 5.5 4 2 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG16638.1 - 1.6e-08 34.1 17.3 0.00041 20.4 0.1 6.5 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG16638.1 - 4.6e-07 29.4 3.4 0.36 10.5 0.0 5.5 3 1 2 5 5 5 2 TPR repeat TPR_14 PF13428.6 EGG16638.1 - 9.8e-07 29.1 0.0 0.16 12.9 0.2 4.1 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG16638.1 - 3.6e-06 27.0 0.3 2 9.0 0.0 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG16638.1 - 4.5e-06 27.1 0.5 0.025 15.1 0.0 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG16638.1 - 0.0043 17.0 6.5 40 4.6 0.0 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGG16638.1 - 0.0082 16.3 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat MAS20 PF02064.15 EGG16638.1 - 0.0092 16.1 18.8 0.38 10.8 0.8 3.7 2 2 1 3 3 3 1 MAS20 protein import receptor TPR_15 PF13429.6 EGG16638.1 - 0.013 14.7 0.5 1 8.5 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EGG16638.1 - 0.019 15.0 9.9 0.58 10.3 0.6 4.0 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EGG16638.1 - 0.046 14.4 1.2 1.4e+02 3.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2347 PF09804.9 EGG16638.1 - 0.11 12.1 2.0 0.2 11.2 2.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) UBN_AB PF14075.6 EGG16638.1 - 0.23 11.2 11.4 0.13 12.0 8.2 2.2 2 0 0 2 2 2 0 Ubinuclein conserved middle domain DDHD PF02862.17 EGG16638.1 - 0.4 10.8 4.0 0.061 13.5 0.4 1.6 2 0 0 2 2 2 0 DDHD domain TPR_10 PF13374.6 EGG16638.1 - 0.4 10.6 1.8 3.6 7.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat HXXSHH PF07586.11 EGG16638.1 - 0.45 10.1 3.9 0.28 10.7 2.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) DNA_pol_phi PF04931.13 EGG16638.1 - 0.59 8.2 28.4 0.1 10.7 17.5 2.3 2 0 0 2 2 2 0 DNA polymerase phi BUD22 PF09073.10 EGG16638.1 - 1.1 8.5 16.9 0.13 11.6 11.9 1.8 2 0 0 2 2 2 0 BUD22 Sod_Cu PF00080.20 EGG16639.1 - 1.1e-47 161.7 6.6 1.6e-47 161.3 6.6 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Citrate_synt PF00285.21 EGG16640.1 - 3.1e-136 454.2 0.0 4e-136 453.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Cpn60_TCP1 PF00118.24 EGG16641.1 - 1.4e-67 228.4 10.2 4.4e-38 131.2 1.5 2.9 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family Ras PF00071.22 EGG16641.1 - 6.3e-53 178.7 0.0 1.1e-52 177.9 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG16641.1 - 5.6e-19 68.5 0.0 2e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG16641.1 - 7.8e-08 32.0 0.1 2.9e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG16641.1 - 0.0017 18.4 0.0 0.0039 17.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG16641.1 - 0.0021 18.0 0.2 1.9 8.3 0.0 3.3 4 0 0 4 4 4 2 RsgA GTPase GTP_EFTU PF00009.27 EGG16641.1 - 0.0042 16.6 0.0 0.044 13.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SNF2_N PF00176.23 EGG16642.1 - 5.5e-62 209.5 3.2 5.5e-62 209.5 3.2 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad60-SLD PF11976.8 EGG16642.1 - 2e-24 85.2 4.4 1.2e-05 25.0 0.0 6.2 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Helicase_C PF00271.31 EGG16642.1 - 2e-17 63.5 0.0 2e-17 63.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 EGG16642.1 - 1.3e-10 41.0 0.3 8.5e-10 38.4 0.3 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ubiquitin PF00240.23 EGG16642.1 - 0.041 13.6 13.1 0.068 12.9 0.0 5.1 4 0 0 4 4 4 0 Ubiquitin family Cullin PF00888.22 EGG16643.1 - 3.3e-143 478.5 26.0 4.2e-143 478.2 26.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGG16643.1 - 2.6e-24 85.0 2.1 4.7e-24 84.2 0.7 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain APG17 PF04108.12 EGG16643.1 - 0.0012 18.1 5.6 0.0016 17.6 2.9 2.3 2 0 0 2 2 2 1 Autophagy protein Apg17 7tm_2 PF00002.24 EGG16644.1 - 1.2e-06 28.0 12.0 2e-06 27.3 12.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) EF-hand_1 PF00036.32 EGG16645.1 - 4.4e-24 82.2 12.3 1.7e-05 24.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGG16645.1 - 2.8e-21 75.7 8.5 4.2e-10 39.9 1.2 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGG16645.1 - 1.1e-20 71.7 9.8 2.7e-05 23.8 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGG16645.1 - 7.5e-16 56.8 14.6 0.00046 19.5 1.2 4.6 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGG16645.1 - 2.3e-10 40.2 11.8 0.00024 20.9 0.5 3.7 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGG16645.1 - 3.1e-07 30.7 0.5 0.029 14.7 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGG16645.1 - 3.7e-06 26.8 5.5 0.044 13.7 0.5 3.4 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGG16645.1 - 0.012 15.9 0.5 4.1 7.8 0.1 3.1 2 1 1 3 3 3 0 EF-hand domain EF-hand_2 PF09068.11 EGG16645.1 - 0.013 15.6 0.1 0.83 9.8 0.0 2.2 2 0 0 2 2 2 0 EF hand Dcc1 PF09724.9 EGG16645.1 - 0.057 12.7 0.0 0.067 12.5 0.0 1.1 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 DUF5580 PF17743.1 EGG16645.1 - 0.074 11.6 0.3 0.11 11.0 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) GST_C PF00043.25 EGG16645.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_85 PF03644.13 EGG16647.1 - 1.5e-85 287.3 8.8 1.5e-85 287.3 8.8 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 85 FBA PF04300.13 EGG16647.1 - 6.5e-12 45.5 1.8 1.6e-11 44.2 0.1 2.3 2 0 0 2 2 2 1 F-box associated region Pkinase PF00069.25 EGG16648.1 - 1.9e-55 188.0 0.0 3.4e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16648.1 - 1.1e-52 178.9 0.0 1.6e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG16648.1 - 1.1e-06 27.7 0.0 1.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGG16648.1 - 0.0019 17.7 0.1 0.0034 16.9 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 EGG16648.1 - 0.0036 16.7 0.4 0.0068 15.8 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SKG6 PF08693.10 EGG16648.1 - 0.0043 16.4 1.6 0.0093 15.4 1.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DPBB_1 PF03330.18 EGG16648.1 - 0.12 12.6 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Lytic transglycolase Pox_ser-thr_kin PF05445.11 EGG16648.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Aha1_N PF09229.11 EGG16649.1 - 2.7e-27 95.7 0.1 4.3e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EGG16649.1 - 1.2e-15 57.9 0.2 3.9e-15 56.2 0.1 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Pex2_Pex12 PF04757.14 EGG16649.1 - 0.011 15.3 0.1 0.018 14.6 0.1 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Menin PF05053.13 EGG16649.1 - 0.068 11.5 4.8 0.084 11.2 4.8 1.1 1 0 0 1 1 1 0 Menin DUF4702 PF15774.5 EGG16649.1 - 0.12 11.3 0.8 0.17 10.8 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) ABC2_membrane_3 PF12698.7 EGG16649.1 - 1.9 7.5 6.0 2.5 7.1 6.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Secretin_N_2 PF07655.13 EGG16649.1 - 2.9 8.5 12.4 1.6 9.3 9.7 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain DNA_pol_A PF00476.20 EGG16650.1 - 1.4e-70 238.3 1.9 3.7e-69 233.6 0.0 3.3 3 1 0 3 3 3 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 EGG16650.1 - 3.6e-41 140.7 0.3 3.5e-39 134.3 0.3 2.4 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 EGG16650.1 - 8.9e-23 80.7 0.0 3.7e-22 78.7 0.0 2.2 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold CAP PF00188.26 EGG16650.1 - 4e-13 50.3 2.6 4e-13 50.3 2.6 2.9 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DNA_pol_A_exo1 PF01612.20 EGG16650.1 - 3.8e-12 46.3 0.0 7.9e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HUN PF08729.10 EGG16650.1 - 0.24 11.4 4.4 1.4 9.0 2.6 2.8 2 0 0 2 2 2 0 HPC2 and ubinuclein domain SNF2_N PF00176.23 EGG16651.1 - 1.6e-59 201.4 6.8 4.4e-59 200.0 6.8 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG16651.1 - 3.6e-18 65.9 1.9 1.4e-17 64.1 0.1 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GSAP-16 PF14959.6 EGG16651.1 - 0.24 11.3 1.0 1.1 9.2 0.1 2.7 3 0 0 3 3 3 0 gamma-Secretase-activating protein C-term DUF3439 PF11921.8 EGG16651.1 - 0.26 11.3 5.5 0.92 9.5 5.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ERG2_Sigma1R PF04622.12 EGG16652.1 - 1.3e-07 31.2 0.0 2.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Pex26 PF07163.12 EGG16652.1 - 0.74 9.1 8.2 0.32 10.3 2.7 2.1 1 1 1 2 2 2 0 Pex26 protein CPSF100_C PF13299.6 EGG16654.1 - 0.0099 16.1 4.2 0.0099 16.1 4.2 2.8 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Kei1 PF08552.11 EGG16655.1 - 0.082 12.8 0.6 0.11 12.3 0.6 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Neur_chan_memb PF02932.16 EGG16655.1 - 0.11 12.6 2.9 0.12 12.4 2.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 EGG16655.1 - 0.18 10.5 13.7 0.28 9.9 13.7 1.4 1 0 0 1 1 1 0 Presenilin RIFIN PF02009.16 EGG16655.1 - 0.25 11.2 16.5 0.1 12.5 14.6 1.3 1 1 0 1 1 1 0 Rifin Tim54 PF11711.8 EGG16655.1 - 0.35 9.6 9.4 0.48 9.1 9.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ALMT PF11744.8 EGG16655.1 - 1.5 7.6 14.1 1.8 7.3 14.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PNISR PF15996.5 EGG16655.1 - 1.7 8.9 12.4 2.2 8.5 12.4 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Ten_N PF06484.12 EGG16655.1 - 2.8 7.7 16.5 3.5 7.4 16.5 1.1 1 0 0 1 1 1 0 Teneurin Intracellular Region CAC1F_C PF16885.5 EGG16655.1 - 2.9 7.5 10.8 3.6 7.2 10.8 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Pro_isomerase PF00160.21 EGG16656.1 - 2.9e-46 157.6 0.1 4.5e-46 157.0 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CBS PF00571.28 EGG16656.1 - 2.6e-11 43.8 0.0 0.00091 19.6 0.0 3.4 3 0 0 3 3 3 3 CBS domain Beach PF02138.18 EGG16657.1 - 1.3e-115 385.5 1.6 2.4e-115 384.7 1.6 1.4 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 EGG16657.1 - 6.6e-22 78.1 1.4 1.9e-21 76.5 0.4 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 EGG16657.1 - 2.2e-20 72.6 0.7 1.5e-19 70.0 0.1 2.9 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 EGG16657.1 - 2.4e-11 44.0 0.0 1.1e-10 41.8 0.0 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 EGG16657.1 - 1.6e-05 25.5 8.0 0.055 14.4 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat GRAM PF02893.20 EGG16657.1 - 3.1e-05 23.8 0.2 0.0001 22.1 0.2 1.9 1 0 0 1 1 1 1 GRAM domain ANAPC4_WD40 PF12894.7 EGG16657.1 - 0.024 14.9 0.1 5.9 7.3 0.0 3.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MxiM PF11441.8 EGG16657.1 - 0.083 13.2 0.7 0.25 11.6 0.1 2.1 2 0 0 2 2 2 0 Pilot protein MxiM cEGF PF12662.7 EGG16657.1 - 0.15 12.1 0.2 0.41 10.6 0.2 1.8 1 0 0 1 1 1 0 Complement Clr-like EGF-like Roughex PF06020.11 EGG16657.1 - 7.7 5.5 13.5 4.6 6.2 0.6 2.3 2 0 0 2 2 2 0 Drosophila roughex protein PNP_UDP_1 PF01048.20 EGG16658.1 - 2.4e-29 102.2 0.0 2.9e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4335 PF14233.6 EGG16658.1 - 0.028 14.3 0.2 0.26 11.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4335) BAF1_ABF1 PF04684.13 EGG16659.1 - 0.0018 17.4 5.8 0.0018 17.4 5.8 2.0 1 1 1 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor DUF3543 PF12063.8 EGG16660.1 - 0.074 12.4 0.5 0.16 11.3 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) DUF5347 PF17282.2 EGG16664.1 - 0.00075 19.8 1.8 0.0011 19.2 1.6 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5347) MACPF PF01823.19 EGG16666.1 - 1.8e-17 64.1 5.4 1.8e-17 64.1 5.4 2.1 2 0 0 2 2 2 1 MAC/Perforin domain MACPF PF01823.19 EGG16667.1 - 1.7e-26 93.7 9.1 1.7e-26 93.7 9.1 2.6 1 1 1 2 2 2 1 MAC/Perforin domain SNAD4 PF18750.1 EGG16669.1 - 2.9e-05 24.1 0.1 5.7e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 SNAD2 PF18745.1 EGG16669.1 - 4.4e-05 23.3 0.2 8.8e-05 22.3 0.2 1.6 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 2 DAAD PF18752.1 EGG16669.1 - 6.5e-05 22.9 7.7 0.00011 22.2 7.7 1.4 1 1 0 1 1 1 1 Dictyosteliid AID/APOBEC-like Deaminase NAD1 PF18778.1 EGG16669.1 - 0.00048 20.3 1.0 0.00075 19.6 0.2 1.7 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 EGG16669.1 - 0.00084 19.4 0.1 0.0016 18.6 0.1 1.5 1 0 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 EGG16669.1 - 0.0016 18.6 1.1 0.0024 18.0 0.1 1.7 2 1 0 2 2 2 1 Novel AID APOBEC clade 2 dCMP_cyt_deam_1 PF00383.23 EGG16669.1 - 0.0066 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Toxin-deaminase PF14424.6 EGG16669.1 - 0.011 15.8 0.4 0.019 15.0 0.4 1.6 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases APOBEC3 PF18771.1 EGG16669.1 - 0.026 14.6 0.2 0.026 14.6 0.2 1.7 2 0 0 2 2 2 0 APOBEC3 PH PF00169.29 EGG16670.1 - 3.2e-17 62.9 3.5 1.6e-16 60.7 0.1 2.4 2 0 0 2 2 2 1 PH domain TPR_12 PF13424.6 EGG16670.1 - 4.2e-08 33.4 0.0 1.8e-06 28.1 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG16670.1 - 0.00034 20.4 0.1 0.88 9.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Secretin_N_2 PF07655.13 EGG16670.1 - 0.0019 18.7 12.2 0.0039 17.7 11.4 1.9 2 0 0 2 2 2 1 Secretin N-terminal domain PH_11 PF15413.6 EGG16670.1 - 0.0046 17.4 0.6 0.0046 17.4 0.6 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 EGG16670.1 - 0.0051 17.1 0.0 0.017 15.3 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain DnaJ-X PF14308.6 EGG16670.1 - 0.021 14.3 3.4 0.037 13.5 3.4 1.3 1 0 0 1 1 1 0 X-domain of DnaJ-containing PPR PF01535.20 EGG16670.1 - 0.44 10.9 2.8 6.9 7.2 0.0 3.6 4 0 0 4 4 4 0 PPR repeat SmAKAP PF15127.6 EGG16670.1 - 0.92 10.7 4.7 1.9 9.7 4.0 1.9 1 1 0 1 1 1 0 Small membrane A-kinase anchor protein LMBR1 PF04791.16 EGG16670.1 - 0.94 8.3 5.0 1.4 7.7 5.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Myb_DNA-binding PF00249.31 EGG16671.1 - 2.2e-25 88.6 8.1 8e-13 48.4 0.4 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG16671.1 - 8.5e-19 67.6 9.2 1.9e-12 47.3 1.0 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EGG16671.1 - 0.0054 16.8 0.1 3.6 7.6 0.0 3.5 1 1 1 2 2 2 1 SLIDE DNA_pol_phi PF04931.13 EGG16671.1 - 0.049 11.7 29.5 0.12 10.5 29.5 1.6 1 0 0 1 1 1 0 DNA polymerase phi zf-RING_11 PF17123.5 EGG16671.1 - 0.071 12.9 5.5 0.22 11.3 5.5 1.9 1 0 0 1 1 1 0 RING-like zinc finger YL1 PF05764.13 EGG16671.1 - 4 7.5 29.4 0.17 12.0 14.2 2.7 2 0 0 2 2 2 0 YL1 nuclear protein PHD PF00628.29 EGG16671.1 - 5.2 7.0 16.2 0.35 10.8 10.8 2.0 2 0 0 2 2 2 0 PHD-finger CDC45 PF02724.14 EGG16671.1 - 6.1 5.0 21.6 0.62 8.3 15.9 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF659 PF04937.15 EGG16673.1 - 2.4e-11 43.7 3.5 5.8e-11 42.5 2.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 EGG16673.1 - 1.5e-09 37.5 0.1 3.4e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NAF PF03822.14 EGG16673.1 - 0.037 14.2 0.0 0.082 13.1 0.0 1.6 1 0 0 1 1 1 0 NAF domain Mga PF05043.13 EGG16673.1 - 0.053 14.1 2.0 0.88 10.2 0.0 3.0 3 0 0 3 3 3 0 Mga helix-turn-helix domain DDE_1 PF03184.19 EGG16674.1 - 7.4e-10 38.8 0.5 1.3e-09 38.0 0.5 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Remorin_N PF03766.13 EGG16674.1 - 0.24 11.5 0.8 0.55 10.3 0.2 1.9 2 0 0 2 2 2 0 Remorin, N-terminal region RhoGEF PF00621.20 EGG16675.1 - 4.4e-50 170.5 2.6 4.4e-50 170.5 2.6 2.5 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.31 EGG16675.1 - 4.8e-18 65.3 1.3 6.3e-17 61.7 0.5 2.8 2 0 0 2 2 2 1 Calponin homology (CH) domain VHP PF02209.19 EGG16675.1 - 7.5e-13 48.3 3.3 2e-12 46.9 3.3 1.8 1 0 0 1 1 1 1 Villin headpiece domain PH PF00169.29 EGG16675.1 - 1.3e-05 25.6 0.0 4.4e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 EGG16675.1 - 6.4e-05 22.8 0.1 6.4e-05 22.8 0.1 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain IQ PF00612.27 EGG16675.1 - 0.0012 18.5 0.3 0.0025 17.4 0.3 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF2604 PF10790.9 EGG16675.1 - 0.0024 18.1 0.2 0.0086 16.4 0.1 1.9 2 0 0 2 2 2 1 Protein of Unknown function (DUF2604) CDC24 PF06395.11 EGG16675.1 - 0.017 15.4 0.1 0.017 15.4 0.1 2.2 2 0 0 2 2 2 0 CDC24 Calponin Melibiase_C PF17801.1 EGG16675.1 - 0.11 12.6 0.0 0.39 10.8 0.0 1.9 1 0 0 1 1 1 0 Alpha galactosidase C-terminal beta sandwich domain DUF543 PF04418.12 EGG16676.1 - 0.00016 21.6 0.0 0.00036 20.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Adeno_PV PF03910.13 EGG16676.1 - 0.0038 16.0 1.1 0.0043 15.8 1.1 1.2 1 0 0 1 1 1 1 Adenovirus minor core protein PV Herpes_pp38 PF04846.13 EGG16676.1 - 0.17 11.9 1.6 0.33 10.9 1.6 1.5 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein RhoGAP PF00620.27 EGG16677.1 - 2e-24 86.1 0.0 4.4e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 EGG16677.1 - 8.8e-13 48.3 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mucin PF01456.17 EGG16677.1 - 6.2 6.8 19.8 10 6.1 19.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RasGEF_N PF00618.20 EGG16678.1 - 0.0034 17.6 4.7 0.0034 17.6 4.7 3.2 3 1 0 3 3 3 1 RasGEF N-terminal motif Tannase PF07519.11 EGG16678.1 - 0.14 11.0 4.1 3.3 6.5 2.7 2.2 2 0 0 2 2 2 0 Tannase and feruloyl esterase Methyltransf_12 PF08242.12 EGG16678.1 - 0.37 11.6 6.5 0.85 10.4 0.2 2.8 2 0 0 2 2 2 0 Methyltransferase domain adh_short PF00106.25 EGG16680.1 - 4.4e-38 130.7 0.0 1.1e-37 129.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG16680.1 - 3.7e-25 88.9 0.0 6.6e-25 88.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG16680.1 - 3.1e-10 40.2 0.0 5.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG16680.1 - 1.4e-06 27.9 0.2 2.7e-06 27.0 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGG16680.1 - 7.3e-05 22.1 0.2 0.00021 20.6 0.2 1.8 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGG16680.1 - 0.0005 19.6 0.8 0.0011 18.4 0.8 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 EGG16680.1 - 0.00082 18.8 0.1 0.0014 18.1 0.1 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 EGG16680.1 - 0.088 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_3 PF03447.16 EGG16680.1 - 0.17 12.6 0.0 0.3 11.7 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain EB PF01683.18 EGG16681.1 - 0.0023 18.2 27.8 0.0056 17.0 11.9 8.1 3 3 5 8 8 8 5 EB module Dickkopf_N PF04706.12 EGG16681.1 - 0.012 16.0 11.8 0.012 16.0 11.8 7.1 4 3 4 8 8 8 0 Dickkopf N-terminal cysteine-rich region p450 PF00067.22 EGG16682.1 - 9.2e-71 238.9 0.0 9.2e-71 238.9 0.0 2.6 3 0 0 3 3 3 1 Cytochrome P450 RasGEF PF00617.19 EGG16682.1 - 2.4e-44 151.6 0.3 2.4e-44 151.6 0.3 3.2 3 1 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 EGG16682.1 - 5.2e-14 52.4 0.5 5.2e-14 52.4 0.5 5.4 3 2 1 4 4 4 1 RasGEF N-terminal motif IMD PF08397.11 EGG16682.1 - 0.011 15.2 1.6 0.018 14.5 0.4 1.9 2 0 0 2 2 2 0 IRSp53/MIM homology domain Dicty_spore_N PF04562.12 EGG16683.1 - 1.5e-47 161.0 58.4 7.3e-25 87.9 32.3 3.1 4 0 0 4 4 4 2 Dictyostelium spore coat protein, N terminus Prefoldin_2 PF01920.20 EGG16685.1 - 2.6e-23 82.0 4.1 3e-23 81.8 4.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit Seryl_tRNA_N PF02403.22 EGG16685.1 - 0.0013 19.0 4.7 0.5 10.6 0.2 2.1 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Nsp1_C PF05064.13 EGG16685.1 - 0.0029 17.4 2.8 0.32 10.8 0.0 2.1 2 0 0 2 2 2 2 Nsp1-like C-terminal region CASP_C PF08172.12 EGG16685.1 - 0.0093 15.3 0.8 0.011 15.1 0.8 1.1 1 0 0 1 1 1 1 CASP C terminal SPACA9 PF15120.6 EGG16685.1 - 0.011 15.6 2.5 0.042 13.6 2.5 1.8 1 1 0 1 1 1 0 Sperm acrosome-associated protein 9 DUF3502 PF12010.8 EGG16685.1 - 0.013 16.1 0.7 0.018 15.7 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) Prefoldin PF02996.17 EGG16685.1 - 0.029 14.3 3.9 0.16 11.9 0.1 2.1 1 1 1 2 2 2 0 Prefoldin subunit RecG_N PF17190.4 EGG16685.1 - 0.042 14.6 1.5 0.84 10.4 0.1 2.2 1 1 1 2 2 2 0 RecG N-terminal helical domain DUF4358 PF14270.6 EGG16685.1 - 0.042 14.1 2.8 0.33 11.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) APG6_N PF17675.1 EGG16685.1 - 0.068 13.7 4.0 0.88 10.1 0.1 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region DEAD PF00270.29 EGG16686.1 - 2.1e-21 76.5 0.0 5.3e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG16686.1 - 1.2e-15 57.8 0.2 1.2e-15 57.8 0.2 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 EGG16686.1 - 1.2e-05 26.0 0.1 4.5e-05 24.1 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Ank_2 PF12796.7 EGG16687.1 - 3.8e-44 149.2 13.9 4e-12 46.5 0.0 6.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) SIR2 PF02146.17 EGG16687.1 - 5.2e-43 147.0 0.0 1.1e-42 146.0 0.0 1.6 1 0 0 1 1 1 1 Sir2 family Ank PF00023.30 EGG16687.1 - 1.1e-37 126.9 15.2 1.5e-06 28.4 0.0 9.3 9 1 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 EGG16687.1 - 2e-35 120.7 4.4 1e-06 29.2 0.1 7.4 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16687.1 - 3.5e-32 106.8 8.6 0.00046 20.4 0.1 9.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 EGG16687.1 - 6.6e-32 109.2 5.1 5.6e-07 29.7 0.0 6.8 4 2 3 7 7 7 5 Ankyrin repeats (many copies) DHC PF09626.10 EGG16687.1 - 1.9 9.4 7.2 31 5.5 0.3 3.8 3 1 1 4 4 4 0 Dihaem cytochrome c p450 PF00067.22 EGG16688.1 - 6.2e-91 305.5 0.0 7.1e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGG16689.1 - 4e-96 322.6 0.0 4.5e-96 322.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CPBP PF02517.16 EGG16690.1 - 6.7e-18 64.9 5.3 6.7e-18 64.9 5.3 2.1 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease zf-C3HC4 PF00097.25 EGG16690.1 - 1.9e-09 37.2 11.8 4.4e-09 36.1 11.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG16690.1 - 1.9e-09 37.2 11.3 1.9e-09 37.2 11.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG16690.1 - 9e-09 35.1 10.2 1.9e-08 34.0 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG16690.1 - 1.9e-07 31.0 7.1 2.3e-07 30.7 4.7 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGG16690.1 - 2.1e-07 31.1 10.8 4.9e-07 30.0 10.8 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EGG16690.1 - 8.4e-06 25.6 7.6 2.2e-05 24.2 7.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGG16690.1 - 1.2e-05 25.4 8.9 2.8e-05 24.2 8.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGG16690.1 - 2.1e-05 24.4 9.7 2.1e-05 24.4 9.7 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 EGG16690.1 - 0.00026 20.8 2.5 0.0007 19.4 2.5 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EGG16690.1 - 0.00061 20.0 6.4 0.0017 18.6 6.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Rad50_zn_hook PF04423.14 EGG16690.1 - 0.003 17.3 2.1 0.2 11.5 0.0 2.6 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Nse PF11789.8 EGG16690.1 - 0.0049 16.7 7.9 0.013 15.3 7.9 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Tim54 PF11711.8 EGG16690.1 - 0.15 10.8 2.9 0.27 10.0 2.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1644 PF07800.12 EGG16690.1 - 0.16 12.1 9.2 0.34 11.0 9.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-P11 PF03854.14 EGG16690.1 - 0.59 9.8 6.8 1.3 8.7 6.8 1.5 1 0 0 1 1 1 0 P-11 zinc finger PRC2_HTH_1 PF18118.1 EGG16690.1 - 1.2 10.0 8.6 2.2 9.2 8.6 1.3 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain zf-RING_4 PF14570.6 EGG16690.1 - 1.7 8.5 8.7 3.8 7.4 8.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGG16690.1 - 4.8 7.3 7.3 3 7.9 4.8 2.0 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EGG16690.1 - 8.6 6.2 13.7 8.1 6.3 8.6 2.6 2 0 0 2 2 2 0 RING-like zinc finger Sec16_C PF12931.7 EGG16691.1 - 1.8e-08 34.4 0.8 4.6e-07 29.8 0.8 2.5 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 EGG16691.1 - 6.3e-07 29.3 0.4 1.1e-05 25.2 0.0 2.7 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 EGG16691.1 - 5.2e-06 27.1 9.8 0.0098 16.7 0.1 5.5 5 1 0 5 5 5 2 WD domain, G-beta repeat Prp18 PF02840.15 EGG16691.1 - 0.0032 17.5 0.1 0.0082 16.2 0.1 1.7 1 0 0 1 1 1 1 Prp18 domain AP-5_subunit_s1 PF15001.6 EGG16692.1 - 6.9e-25 88.2 0.0 3.4e-21 76.1 0.0 2.7 1 1 0 1 1 1 1 AP-5 complex subunit sigma-1 Clat_adaptor_s PF01217.20 EGG16692.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain SR-25 PF10500.9 EGG16692.1 - 1.1 8.8 4.6 0.84 9.2 2.3 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ABC2_membrane PF01061.24 EGG16693.1 - 3.6e-74 248.7 68.6 4.9e-42 143.7 24.0 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGG16693.1 - 4.9e-40 137.2 0.0 2.2e-19 70.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGG16693.1 - 7.5e-30 102.7 4.2 6.7e-25 86.8 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EGG16693.1 - 8.5e-12 45.5 0.1 2.3e-11 44.1 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EGG16693.1 - 8.7e-08 32.2 0.1 2.1e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGG16693.1 - 3.6e-06 26.6 0.5 0.0059 16.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG16693.1 - 0.00041 20.8 0.0 0.68 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGG16693.1 - 0.00084 19.6 0.0 0.48 10.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGG16693.1 - 0.00099 19.0 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EGG16693.1 - 0.0023 17.5 0.1 0.0072 15.9 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGG16693.1 - 0.0086 15.8 0.2 2.3 7.9 0.6 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGG16693.1 - 0.014 15.5 0.2 4.8 7.3 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 EGG16693.1 - 0.017 15.7 1.8 1.2 9.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EGG16693.1 - 0.022 14.0 0.8 3.7 6.8 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin Rad17 PF03215.15 EGG16693.1 - 0.027 14.4 0.2 5.1 7.0 0.0 3.2 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_33 PF13671.6 EGG16693.1 - 0.029 14.5 0.7 1.8 8.8 0.4 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGG16693.1 - 0.03 13.9 0.1 0.59 9.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EGG16693.1 - 0.09 12.5 0.1 0.41 10.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGG16693.1 - 0.097 13.1 0.1 29 5.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 EGG16693.1 - 0.11 13.0 0.1 4.3 7.8 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EGG16693.1 - 0.15 11.8 0.4 1.5 8.5 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EGG16693.1 - 0.19 11.6 0.9 6.5 6.6 0.7 2.3 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EGG16693.1 - 0.32 11.2 0.8 1.7 8.9 0.8 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGG16693.1 - 1.1 9.7 5.4 1.1 9.7 0.1 3.1 3 0 0 3 3 2 0 AAA domain MMS19_N PF14500.6 EGG16695.1 - 7.6e-84 281.4 5.8 7.8e-83 278.0 0.4 4.1 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 EGG16695.1 - 7.7e-44 150.5 43.3 7.7e-44 150.5 43.3 3.3 2 2 1 3 3 3 1 RNAPII transcription regulator C-terminal HEAT PF02985.22 EGG16695.1 - 0.0062 16.7 3.4 1.6 9.2 0.1 4.7 4 0 0 4 4 4 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EGG16695.1 - 0.42 11.2 4.1 5.3 7.7 0.1 4.3 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region RPEL PF02755.15 EGG16696.1 - 6e-09 35.3 15.7 0.027 14.1 0.1 6.0 6 0 0 6 6 6 5 RPEL repeat Indigoidine_A PF04227.12 EGG16697.1 - 1.1e-123 412.3 6.9 2.2e-123 411.3 6.9 1.6 1 0 0 1 1 1 1 Indigoidine synthase A like protein RSN1_7TM PF02714.15 EGG16697.1 - 8.3e-68 228.6 24.1 8.3e-68 228.6 24.1 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGG16697.1 - 1.2e-32 112.8 4.8 1.2e-32 112.8 4.8 3.6 5 0 0 5 5 5 1 Late exocytosis, associated with Golgi transport PfkB PF00294.24 EGG16697.1 - 6.8e-29 101.1 0.9 6.9e-18 65.0 0.0 2.8 3 0 0 3 3 3 2 pfkB family carbohydrate kinase PHM7_cyt PF14703.6 EGG16697.1 - 4.5e-21 75.9 3.5 1.9e-15 57.6 0.0 3.0 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter DUF3593 PF12159.8 EGG16697.1 - 0.025 14.6 4.2 0.17 12.0 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) ERM PF00769.19 EGG16698.1 - 8.9e-07 29.0 18.0 8.9e-07 29.0 18.0 4.2 3 1 1 4 4 4 1 Ezrin/radixin/moesin family MbeD_MobD PF04899.12 EGG16698.1 - 0.15 12.2 4.4 0.23 11.6 0.1 3.0 2 1 0 2 2 2 0 MbeD/MobD like SKA2 PF16740.5 EGG16700.1 - 1.6e-27 95.4 1.3 1.6e-27 95.4 1.3 2.4 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 DUF3161 PF11362.8 EGG16700.1 - 0.0015 18.4 0.3 0.32 11.0 0.1 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3161) SKA1 PF07160.12 EGG16700.1 - 0.0028 17.5 12.4 0.0028 17.5 12.4 2.2 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 1 Thioredoxin_8 PF13905.6 EGG16700.1 - 0.088 13.1 2.2 3.2 8.1 0.3 2.6 2 0 0 2 2 2 0 Thioredoxin-like RNA_pol_Rpb2_7 PF04560.20 EGG16700.1 - 0.1 13.0 1.5 6.3 7.3 0.1 2.8 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 7 YabA PF06156.13 EGG16700.1 - 2.8 8.6 10.3 4.8 7.9 0.3 2.8 3 0 0 3 3 3 0 Initiation control protein YabA SUIM_assoc PF16619.5 EGG16700.1 - 4.2 7.5 16.6 5.7 7.1 15.1 2.2 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4518 PF15008.6 EGG16701.1 - 2.7 7.1 6.8 0.36 10.0 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) FAM176 PF14851.6 EGG16701.1 - 3.2 7.4 13.1 2.4 7.8 0.5 3.0 3 0 0 3 3 3 0 FAM176 family Bact_lectin PF18483.1 EGG16702.1 - 9.9e-25 87.7 2.3 9.9e-25 87.7 2.3 2.5 3 0 0 3 3 3 1 Bacterial lectin Lectin_legB PF00139.19 EGG16702.1 - 7e-19 68.3 0.5 1.3e-18 67.5 0.5 1.4 1 0 0 1 1 1 1 Legume lectin domain Transglut_core PF01841.19 EGG16702.1 - 1.4e-14 54.5 1.1 3.1e-14 53.4 1.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 EGG16702.1 - 6e-10 39.0 1.2 6e-10 39.0 1.2 2.3 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain Lectin_leg-like PF03388.13 EGG16702.1 - 1.1e-09 38.0 3.5 2.9e-09 36.6 3.5 1.7 1 0 0 1 1 1 1 Legume-like lectin family ubiquitin PF00240.23 EGG16702.1 - 0.00049 19.8 0.5 0.00049 19.8 0.5 2.1 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGG16702.1 - 0.0015 18.9 0.2 0.0015 18.9 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain PAW PF04721.17 EGG16702.1 - 0.0065 16.3 0.1 0.018 14.8 0.1 1.8 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Ank_2 PF12796.7 EGG16703.1 - 6.4e-29 100.4 0.9 5.7e-11 42.9 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16703.1 - 1.7e-24 85.9 3.4 3.3e-09 37.1 0.0 4.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16703.1 - 8e-23 78.1 0.1 0.0013 19.1 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EGG16703.1 - 5.5e-19 68.0 1.1 9.6e-05 22.6 0.0 5.7 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EGG16703.1 - 3.9e-14 52.4 1.6 0.0042 17.5 0.1 5.8 6 0 0 6 6 6 4 Ankyrin repeat RhoGEF PF00621.20 EGG16704.1 - 3.2e-47 161.1 1.5 8.8e-47 159.7 1.5 1.8 1 0 0 1 1 1 1 RhoGEF domain CH PF00307.31 EGG16704.1 - 2.5e-46 156.3 9.0 4.2e-17 62.3 0.4 3.6 3 0 0 3 3 3 3 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGG16704.1 - 3.7e-07 29.9 3.7 0.12 12.3 0.2 5.1 4 1 1 5 5 5 2 CAMSAP CH domain PH PF00169.29 EGG16704.1 - 2.4e-05 24.8 1.0 0.00019 21.9 1.0 2.7 1 0 0 1 1 1 1 PH domain CDC24 PF06395.11 EGG16704.1 - 0.00028 21.1 1.0 0.44 10.8 0.0 2.9 2 0 0 2 2 2 2 CDC24 Calponin Peptidase_S49_N PF08496.10 EGG16704.1 - 0.089 12.9 1.1 0.2 11.7 1.1 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal E7 PF00527.18 EGG16704.1 - 0.2 11.9 5.5 0.16 12.2 0.7 2.7 2 0 0 2 2 2 0 E7 protein, Early protein IQ_SEC7_PH PF16453.5 EGG16704.1 - 0.32 11.0 3.5 1.6 8.7 1.8 2.8 2 1 0 2 2 2 0 PH domain DUF4611 PF15387.6 EGG16704.1 - 5.4 7.3 9.1 3.7 7.8 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) YrhC PF14143.6 EGG16705.1 - 0.095 12.8 0.1 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 YrhC-like protein Ank_4 PF13637.6 EGG16706.1 - 2.9e-25 88.3 14.8 3.7e-06 27.4 0.1 5.6 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG16706.1 - 2.7e-23 82.3 7.0 1.4e-08 35.2 0.2 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG16706.1 - 3.4e-14 52.7 9.0 0.15 12.5 0.1 7.6 1 1 7 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16706.1 - 1.4e-13 49.7 3.3 1.4 9.7 0.0 8.1 5 2 3 8 8 8 3 Ankyrin repeat DUF5049 PF16468.5 EGG16706.1 - 5.7e-07 29.3 0.4 17 5.4 0.0 6.2 3 2 3 6 6 6 1 Domain of unknown function (DUF5049) Ank PF00023.30 EGG16706.1 - 8.2e-07 29.2 0.7 2.4 8.7 0.0 6.5 2 1 2 4 4 4 1 Ankyrin repeat Vps23_core PF09454.10 EGG16706.1 - 0.12 12.3 0.0 8.6 6.4 0.0 3.6 3 1 1 4 4 4 0 Vps23 core domain Patatin PF01734.22 EGG16708.1 - 6e-25 88.6 0.0 8.5e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase DUF1374 PF07118.11 EGG16708.1 - 0.044 14.3 2.0 0.057 13.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) Senescence PF06911.12 EGG16708.1 - 0.13 12.5 0.2 0.36 11.1 0.1 1.6 1 1 0 1 1 1 0 Senescence-associated protein DUF4262 PF14081.6 EGG16710.1 - 0.13 12.4 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) EF-hand_1 PF00036.32 EGG16710.1 - 0.17 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EGG16710.1 - 0.18 11.8 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain 2OG-FeII_Oxy_3 PF13640.6 EGG16711.1 - 7.3e-14 52.4 0.0 1.7e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Actin PF00022.19 EGG16711.1 - 5.5e-12 45.0 0.7 3.8e-10 38.9 0.0 2.2 1 1 0 2 2 2 2 Actin Pox_C4_C10 PF03336.13 EGG16711.1 - 0.00066 18.9 0.0 0.0018 17.5 0.0 1.7 1 1 0 1 1 1 1 Poxvirus C4/C10 protein F-box PF00646.33 EGG16711.1 - 0.054 13.4 0.0 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 F-box domain PhyH PF05721.13 EGG16711.1 - 0.18 12.1 0.0 23 5.1 0.0 2.8 3 0 0 3 3 3 0 Phytanoyl-CoA dioxygenase (PhyH) DUF3447 PF11929.8 EGG16712.1 - 0.00034 20.5 11.2 0.02 14.9 0.5 4.5 2 2 2 4 4 4 2 Domain of unknown function (DUF3447) CHAT PF12770.7 EGG16713.1 - 8.4e-25 87.8 0.0 1.6e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EGG16713.1 - 9.7e-05 22.6 3.4 0.29 11.5 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG16713.1 - 0.0046 17.7 0.6 16 6.6 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG16713.1 - 0.065 13.3 2.5 10 6.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SR-25 PF10500.9 EGG16713.1 - 0.14 11.7 3.2 0.31 10.6 3.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_2 PF07719.17 EGG16713.1 - 0.21 11.8 15.5 5.6 7.3 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGG16713.1 - 0.34 11.2 9.7 82 3.8 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGG16713.1 - 1.2 9.1 10.4 15 5.6 0.2 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2729 PF10870.8 EGG16713.1 - 5.5 6.9 10.0 1.4 8.8 4.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2729) Histone PF00125.24 EGG16714.1 - 5.6e-23 81.7 0.3 7.1e-23 81.4 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGG16714.1 - 7.8e-05 22.9 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGG16714.1 - 0.0034 17.8 0.0 0.0081 16.6 0.0 1.6 1 1 0 1 1 1 1 Transcription initiation factor TFIID subunit A Glyco_hydro_38N PF01074.22 EGG16715.1 - 2.2e-70 237.3 0.7 5.8e-67 226.1 0.7 2.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGG16715.1 - 1.4e-18 67.8 0.5 2.6e-18 66.9 0.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGG16715.1 - 1.5e-17 63.5 0.2 4.3e-17 62.0 0.0 1.9 2 0 0 2 2 2 1 Alpha mannosidase middle domain DUF1345 PF07077.11 EGG16716.1 - 0.022 14.5 1.5 2.3 7.9 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) CUE PF02845.16 EGG16718.1 - 0.0032 17.1 2.0 0.0035 17.0 0.3 2.0 2 0 0 2 2 2 1 CUE domain DUF1296 PF06972.11 EGG16718.1 - 0.013 15.6 1.2 0.029 14.5 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) WW PF00397.26 EGG16719.1 - 5.5e-22 77.6 9.8 9.8e-11 41.5 2.2 2.6 2 0 0 2 2 2 2 WW domain C2 PF00168.30 EGG16719.1 - 2.6e-09 37.3 0.3 0.00074 19.8 0.0 3.0 2 1 1 3 3 3 2 C2 domain IQ PF00612.27 EGG16719.1 - 0.032 14.0 0.3 0.082 12.7 0.3 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif UPRTase PF14681.6 EGG16720.1 - 4.2e-75 251.7 0.0 8e-75 250.8 0.0 1.4 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGG16720.1 - 3e-08 33.3 0.0 4.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ketoacyl-synt PF00109.26 EGG16721.1 - 4e-65 219.9 0.1 9.6e-65 218.6 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG16721.1 - 1.2e-47 163.0 0.0 2.1e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EGG16721.1 - 1e-28 100.4 0.0 1.7e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EGG16721.1 - 7.2e-26 91.2 0.0 1.6e-25 90.0 0.0 1.7 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 EGG16721.1 - 1.3e-21 76.8 0.0 3.2e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EGG16721.1 - 1.4e-08 35.9 0.0 4.6e-07 30.9 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGG16721.1 - 6.8e-06 26.1 0.0 3.9e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EGG16721.1 - 1.2e-05 25.6 0.0 3.4e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EGG16721.1 - 2e-05 24.4 0.1 0.00011 22.1 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGG16721.1 - 0.0015 18.0 0.5 0.0036 16.7 0.5 1.6 1 1 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 EGG16721.1 - 0.024 15.3 0.0 0.068 13.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGG16721.1 - 0.089 12.6 0.1 0.29 10.9 0.1 1.9 1 0 0 1 1 1 0 Methyltransferase domain ketoacyl-synt PF00109.26 EGG16722.1 - 3e-63 213.7 0.0 4.6e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG16722.1 - 2.4e-50 171.9 0.0 3.6e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGG16722.1 - 1.9e-34 118.2 0.0 5.2e-34 116.8 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGG16722.1 - 4.4e-13 49.7 0.0 1e-12 48.5 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGG16722.1 - 2.9e-09 36.6 0.0 4.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 EGG16722.1 - 0.0025 17.2 0.3 0.0093 15.4 0.3 1.9 1 1 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.10 EGG16723.1 - 2.7e-26 92.6 0.0 7.2e-26 91.2 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGG16723.1 - 3e-10 39.8 0.0 4.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EGG16723.1 - 2.2e-09 38.5 0.0 1.3e-07 32.7 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGG16723.1 - 1.6e-08 34.6 0.0 3e-07 30.5 0.0 3.0 4 0 0 4 4 4 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG16723.1 - 2.8e-06 27.2 0.0 2.8e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGG16723.1 - 5e-06 26.8 0.0 1.7e-05 25.0 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 EGG16723.1 - 0.007 17.0 0.0 0.022 15.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG16723.1 - 0.028 14.2 0.1 0.099 12.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain ketoacyl-synt PF00109.26 EGG16724.1 - 1.8e-62 211.2 0.1 2.8e-62 210.6 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG16724.1 - 2.8e-48 165.0 0.0 4.7e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGG16724.1 - 1e-34 119.1 0.0 2.3e-34 117.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGG16724.1 - 1.1e-24 87.3 0.0 2.8e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGG16724.1 - 1.4e-23 83.6 0.0 2.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGG16724.1 - 7.4e-13 48.9 0.0 2.4e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 EGG16724.1 - 2.2e-07 30.9 0.0 8.2e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGG16724.1 - 4.1e-07 31.1 0.0 1.2e-06 29.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG16724.1 - 6e-06 26.1 0.2 2e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGG16724.1 - 1e-05 25.8 0.0 3.1e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGG16724.1 - 0.0076 15.6 0.3 0.023 14.1 0.3 1.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain DEAD PF00270.29 EGG16725.1 - 8.8e-51 172.2 0.0 2.6e-50 170.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG16725.1 - 9.8e-32 109.6 0.0 2.8e-30 104.9 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG16725.1 - 0.00057 19.9 0.1 0.0029 17.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGG16725.1 - 0.00097 18.4 0.1 0.00097 18.4 0.1 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Macoilin PF09726.9 EGG16725.1 - 0.58 8.6 4.9 0.81 8.2 4.9 1.1 1 0 0 1 1 1 0 Macoilin family MMR_HSR1 PF01926.23 EGG16726.1 - 0.0014 18.7 0.0 0.0052 16.9 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase MACPF PF01823.19 EGG16726.1 - 0.0023 18.1 4.0 0.0069 16.5 4.0 1.9 1 0 0 1 1 1 1 MAC/Perforin domain AAA_23 PF13476.6 EGG16726.1 - 0.0036 17.8 0.7 0.0036 17.8 0.7 3.9 3 1 0 3 3 3 2 AAA domain GTP_EFTU PF00009.27 EGG16726.1 - 0.0053 16.3 0.4 0.014 14.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MORN PF02493.20 EGG16726.1 - 3.3 7.8 4.9 0.95 9.5 0.9 2.3 2 0 0 2 2 2 0 MORN repeat AAA_23 PF13476.6 EGG16727.1 - 0.0018 18.8 0.4 0.0018 18.8 0.4 3.3 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 EGG16727.1 - 0.0029 16.7 0.0 0.0077 15.3 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 EGG16727.1 - 0.0088 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tup_N PF08581.10 EGG16727.1 - 0.032 14.5 0.6 0.12 12.7 0.6 2.1 1 0 0 1 1 1 0 Tup N-terminal RSS_P20 PF11757.8 EGG16727.1 - 0.052 14.0 2.0 1 9.9 0.0 3.5 3 0 0 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain AAA_33 PF13671.6 EGG16727.1 - 0.076 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG16727.1 - 0.16 12.3 0.0 0.43 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Fer4_6 PF12837.7 EGG16727.1 - 0.26 11.4 1.2 0.75 10.0 1.2 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain MORN PF02493.20 EGG16727.1 - 0.68 9.9 6.2 0.27 11.2 0.1 3.0 3 0 0 3 3 3 0 MORN repeat Fer4_9 PF13187.6 EGG16727.1 - 3 8.1 9.0 7.5 6.8 9.0 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain ABC_tran PF00005.27 EGG16728.1 - 1.2e-45 155.4 12.0 5e-23 82.1 0.0 4.1 3 1 1 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 EGG16728.1 - 1.5e-27 95.4 4.2 1.5e-27 95.4 4.2 2.9 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 EGG16728.1 - 3.5e-16 59.9 4.5 0.0011 18.9 0.3 4.4 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGG16728.1 - 9.5e-09 35.4 0.1 0.0022 17.8 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 EGG16728.1 - 1.2e-08 35.7 6.0 0.0011 19.5 0.1 4.3 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EGG16728.1 - 1.6e-07 31.8 0.7 0.0067 16.8 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 EGG16728.1 - 4.8e-07 29.8 0.1 0.016 15.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 EGG16728.1 - 1.1e-06 29.0 1.1 0.065 13.5 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGG16728.1 - 1.1e-06 29.2 7.2 0.02 15.5 0.0 4.0 5 0 0 5 5 3 2 AAA domain AAA PF00004.29 EGG16728.1 - 5.2e-06 26.9 0.4 0.24 11.9 0.1 3.7 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EGG16728.1 - 1.1e-05 25.5 0.8 0.056 13.5 0.1 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EGG16728.1 - 1.3e-05 25.5 0.0 0.33 11.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGG16728.1 - 2.8e-05 24.1 1.4 0.029 14.3 0.3 2.7 2 1 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EGG16728.1 - 3.6e-05 23.6 0.0 0.23 11.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 EGG16728.1 - 3.8e-05 23.2 2.7 0.0063 16.0 2.7 3.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 EGG16728.1 - 5e-05 23.3 0.7 1 9.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EGG16728.1 - 5.5e-05 22.8 0.6 0.26 11.1 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain PduV-EutP PF10662.9 EGG16728.1 - 6.2e-05 22.8 0.1 0.39 10.4 0.0 2.9 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EGG16728.1 - 0.0001 22.1 0.2 0.91 9.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain Roc PF08477.13 EGG16728.1 - 0.00021 21.5 0.2 1.2 9.4 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EGG16728.1 - 0.00027 20.2 0.0 0.62 9.2 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_7 PF12775.7 EGG16728.1 - 0.0005 19.6 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 EGG16728.1 - 0.0009 18.9 0.6 0.92 9.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.6 EGG16728.1 - 0.001 19.1 2.1 1.6 8.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain DUF3584 PF12128.8 EGG16728.1 - 0.002 15.8 0.1 0.002 15.8 0.1 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF3584) cobW PF02492.19 EGG16728.1 - 0.0021 17.7 0.7 0.52 9.9 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EGG16728.1 - 0.0021 18.0 0.2 1.4 8.8 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 EGG16728.1 - 0.003 17.5 0.3 1 9.2 0.1 2.8 2 0 0 2 2 2 1 NTPase TsaE PF02367.17 EGG16728.1 - 0.0033 17.4 0.2 2.5 8.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGG16728.1 - 0.0042 17.4 0.0 2 8.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase T2SSE PF00437.20 EGG16728.1 - 0.0053 15.8 2.4 0.48 9.4 0.0 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 EGG16728.1 - 0.0088 16.2 12.4 0.22 11.7 0.2 3.8 4 1 0 4 4 3 2 AAA domain Zeta_toxin PF06414.12 EGG16728.1 - 0.0098 15.2 2.1 0.86 8.8 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin GCOM2 PF15328.6 EGG16728.1 - 0.014 15.7 0.0 0.014 15.7 0.0 2.4 4 0 0 4 4 1 0 Putative GRINL1B complex locus protein 2 FeoB_N PF02421.18 EGG16728.1 - 0.015 14.8 0.2 1.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B SRP54 PF00448.22 EGG16728.1 - 0.035 13.7 4.6 0.97 9.0 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EGG16728.1 - 0.043 14.1 3.4 2.5 8.4 0.0 3.3 4 1 0 4 4 3 0 AAA domain AAA_13 PF13166.6 EGG16728.1 - 0.097 11.3 11.1 0.26 9.9 0.0 3.6 4 0 0 4 4 4 0 AAA domain ATPase_2 PF01637.18 EGG16728.1 - 0.1 12.5 0.1 0.1 12.5 0.1 3.0 4 0 0 4 4 2 0 ATPase domain predominantly from Archaea PIN PF01850.21 EGG16728.1 - 0.14 12.7 1.2 16 6.0 0.0 2.8 2 0 0 2 2 2 0 PIN domain Pox_A32 PF04665.12 EGG16728.1 - 0.15 11.5 1.5 12 5.2 0.0 3.1 3 0 0 3 3 3 0 Poxvirus A32 protein ATP-synt_ab PF00006.25 EGG16728.1 - 0.19 11.3 0.0 8.2 6.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3352 PF11832.8 EGG16729.1 - 0.052 12.2 0.1 7.6 5.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3352) LRR_6 PF13516.6 EGG16729.1 - 0.74 10.0 6.3 59 4.1 0.0 4.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_6 PF13516.6 EGG16730.1 - 4.6e-07 29.4 17.4 0.37 11.0 0.1 8.0 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 EGG16730.1 - 0.0025 18.1 4.7 32 5.6 0.0 7.4 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_4 PF12799.7 EGG16730.1 - 0.031 14.7 13.1 3.1 8.3 0.1 6.0 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) PDEase_II PF02112.15 EGG16731.1 - 5.9e-89 298.5 5.3 7.2e-89 298.2 5.3 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II DNA_primase_lrg PF04104.14 EGG16732.1 - 7.3e-59 199.3 0.2 1.4e-58 198.4 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit NDUF_B7 PF05676.13 EGG16732.1 - 0.022 14.5 0.2 0.068 12.9 0.2 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Endotoxin_N PF03945.14 EGG16733.1 - 5.5e-11 42.6 1.0 1.1e-10 41.6 1.0 1.5 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Ricin_B_lectin PF00652.22 EGG16733.1 - 7.8e-06 26.2 3.1 3.8e-05 23.9 0.5 2.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain CIMR PF00878.18 EGG16733.1 - 0.00022 21.3 1.0 0.00022 21.3 1.0 2.7 2 1 1 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat B_lectin PF01453.24 EGG16733.1 - 0.022 15.3 0.3 0.16 12.5 0.0 2.4 2 0 0 2 2 2 0 D-mannose binding lectin RicinB_lectin_2 PF14200.6 EGG16733.1 - 0.076 13.7 4.9 1.6 9.5 0.0 4.1 4 1 0 4 4 4 0 Ricin-type beta-trefoil lectin domain-like ICAT PF06384.11 EGG16735.1 - 0.087 13.1 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT Ank_2 PF12796.7 EGG16736.1 - 0.0092 16.5 0.8 1.3 9.7 0.0 4.0 4 1 1 5 5 5 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG16736.1 - 0.15 12.7 0.1 72 4.5 0.0 4.7 4 0 0 4 4 4 0 Ankyrin repeat Rsbr_N PF08678.10 EGG16736.1 - 0.27 11.3 0.1 0.27 11.3 0.1 4.1 5 0 0 5 5 5 0 Rsbr N terminal Elf1 PF05129.13 EGG16737.1 - 5.4e-30 103.3 2.1 6e-30 103.1 2.1 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 EGG16737.1 - 0.0075 16.6 2.2 0.0094 16.3 2.2 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar zf-BED PF02892.15 EGG16737.1 - 4.6 7.3 6.4 45 4.2 6.4 2.2 1 1 0 1 1 1 0 BED zinc finger Pkinase_Tyr PF07714.17 EGG16739.1 - 2.7e-20 72.7 0.0 4e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG16739.1 - 1.9e-16 60.2 0.0 2.9e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain NOG1_N PF17835.1 EGG16740.1 - 1.1e-53 181.5 0.8 2.7e-53 180.2 0.8 1.7 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 EGG16740.1 - 1.8e-25 88.5 0.6 1.8e-25 88.5 0.6 2.1 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 EGG16740.1 - 4.7e-20 71.3 4.9 1.1e-19 70.1 4.9 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 EGG16740.1 - 1.4e-18 67.0 0.0 6.1e-18 65.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG16740.1 - 2.5e-11 43.4 0.0 4.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 EGG16740.1 - 0.0057 16.0 0.0 0.02 14.2 0.0 1.9 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 EGG16740.1 - 0.017 14.6 0.0 0.13 11.8 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGG16740.1 - 0.022 14.6 0.2 0.58 10.0 0.0 3.1 4 1 0 4 4 4 0 RsgA GTPase Roc PF08477.13 EGG16740.1 - 0.028 14.6 0.0 0.4 10.9 0.0 2.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EGG16740.1 - 0.073 13.1 0.9 12 5.9 0.0 2.8 2 1 1 3 3 3 0 Dynamin family FliT PF05400.13 EGG16740.1 - 6 7.8 8.2 5.3 7.9 6.0 2.1 2 0 0 2 2 1 0 Flagellar protein FliT GRASP55_65 PF04495.14 EGG16741.1 - 4.1e-62 208.5 0.0 3.6e-46 156.9 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 EGG16741.1 - 7e-06 26.3 0.0 0.02 15.2 0.0 2.4 2 0 0 2 2 2 2 PDZ domain CDT1_C PF16679.5 EGG16741.1 - 0.082 13.3 2.6 0.18 12.3 2.6 1.6 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Lin-8 PF03353.15 EGG16741.1 - 0.18 11.3 0.1 0.18 11.3 0.1 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist PRP9_N PF16958.5 EGG16741.1 - 1.1 9.3 11.0 1.9 8.5 11.0 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus DUF4481 PF14800.6 EGG16741.1 - 4.2 6.8 7.1 7.8 5.9 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) PALP PF00291.25 EGG16742.1 - 3e-53 181.2 0.0 3.9e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FNIP PF05725.12 EGG16743.1 - 3.3e-26 91.2 9.1 1.9e-07 31.1 0.0 7.5 6 1 1 7 7 7 5 FNIP Repeat Annexin PF00191.20 EGG16744.1 - 1.4e-72 239.6 7.3 1.1e-19 70.3 0.0 4.1 4 0 0 4 4 4 4 Annexin DUF2312 PF10073.9 EGG16744.1 - 0.086 12.5 0.6 0.23 11.1 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) SfsA PF03749.13 EGG16744.1 - 0.14 12.1 0.1 11 5.9 0.0 2.7 3 0 0 3 3 3 0 Sugar fermentation stimulation protein RE domain NAD_binding_10 PF13460.6 EGG16745.1 - 1.4e-10 41.4 0.0 1.6e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGG16745.1 - 3.5e-05 23.1 0.0 6.3e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 EGG16745.1 - 4.3e-05 23.9 0.0 7.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EGG16745.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG16745.1 - 0.0037 16.3 0.5 0.026 13.5 0.2 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EGG16745.1 - 0.031 14.4 0.1 0.058 13.5 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 EGG16745.1 - 0.033 14.2 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1955 PF09205.10 EGG16745.1 - 0.045 13.5 0.3 0.064 13.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) NmrA PF05368.13 EGG16745.1 - 0.074 12.6 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family GFO_IDH_MocA PF01408.22 EGG16745.1 - 0.14 13.0 0.0 0.21 12.4 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold BB_PF PF18063.1 EGG16746.1 - 3.2e-59 200.0 0.6 4e-59 199.7 0.6 1.1 1 0 0 1 1 1 1 Beta barrel Pore-forming domain DUF577 PF04510.12 EGG16747.1 - 0.069 13.1 0.1 5.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF577) Pkinase PF00069.25 EGG16749.1 - 2.2e-53 181.3 0.3 2.2e-53 181.3 0.3 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16749.1 - 6.3e-23 81.4 0.1 1.2e-22 80.4 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TFIIA PF03153.13 EGG16749.1 - 0.015 15.3 57.9 0.26 11.2 9.4 2.3 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 EGG16749.1 - 0.018 16.0 10.9 0.018 16.0 10.9 6.4 4 3 1 5 5 5 0 Domain of unknown function (DUF4834) APH PF01636.23 EGG16749.1 - 0.069 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TT_ORF2 PF02957.15 EGG16749.1 - 0.25 12.3 3.9 1.9 9.4 0.3 3.3 3 0 0 3 3 3 0 TT viral ORF2 ANAPC15 PF15243.6 EGG16749.1 - 9.6 6.7 11.6 1.7 9.1 2.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 SGL PF08450.12 EGG16750.1 - 8.2e-71 238.5 0.3 9.7e-71 238.2 0.3 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF839 PF05787.13 EGG16750.1 - 0.00049 19.4 0.0 0.00069 18.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) Reg_prop PF07494.11 EGG16750.1 - 0.0014 18.6 0.2 4.6 7.8 0.0 3.5 3 0 0 3 3 3 2 Two component regulator propeller MitMem_reg PF13012.6 EGG16754.1 - 3.5e-19 69.3 0.5 4e-19 69.1 0.5 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function SMP_2 PF10144.9 EGG16754.1 - 0.061 13.0 0.1 0.073 12.7 0.1 1.1 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin JAB PF01398.21 EGG16755.1 - 9.5e-22 77.2 0.0 1.4e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ank_2 PF12796.7 EGG16756.1 - 0.018 15.6 1.0 0.22 12.1 0.0 3.2 4 0 0 4 4 4 0 Ankyrin repeats (3 copies) C2 PF00168.30 EGG16757.1 - 3.2e-07 30.6 0.4 7.5e-07 29.4 0.2 1.8 2 0 0 2 2 2 1 C2 domain Calpain_III PF01067.22 EGG16758.1 - 2.6e-26 92.6 0.0 1.8e-17 64.0 0.0 2.2 2 0 0 2 2 2 2 Calpain large subunit, domain III Sporozoite_P67 PF05642.11 EGG16758.1 - 0.1 10.6 4.7 0.14 10.3 4.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Malic_M PF03949.15 EGG16759.1 - 8.2e-100 333.3 0.2 1.1e-99 332.9 0.2 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EGG16759.1 - 2.7e-72 242.4 0.0 5.8e-72 241.3 0.0 1.6 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DJ-1_PfpI PF01965.24 EGG16760.1 - 3.4e-44 150.6 0.0 3.9e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EGG16760.1 - 0.00055 19.7 0.0 0.0017 18.1 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase PF00117.28 EGG16760.1 - 0.0011 18.8 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EGG16760.1 - 0.0057 16.3 0.0 0.012 15.2 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 EGG16760.1 - 0.0081 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 SNO glutamine amidotransferase family Catalase_C PF18011.1 EGG16760.1 - 0.042 13.5 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases Peptidase_C26 PF07722.13 EGG16760.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase C26 Ank_2 PF12796.7 EGG16761.1 - 1.3e-21 76.9 14.3 2.4e-09 37.6 0.2 4.5 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16761.1 - 3.7e-19 68.8 4.1 0.00091 19.8 0.0 6.5 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16761.1 - 4.5e-16 58.7 7.4 0.1 12.9 0.0 8.3 3 1 6 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16761.1 - 2.9e-11 42.5 2.7 1.8 9.4 0.0 8.9 10 0 0 10 10 10 3 Ankyrin repeat DUF5049 PF16468.5 EGG16761.1 - 0.0001 22.1 0.0 59 3.7 0.1 6.4 5 1 2 7 7 7 0 Domain of unknown function (DUF5049) Ank PF00023.30 EGG16761.1 - 0.0067 16.8 6.9 48 4.6 0.0 7.0 5 2 0 5 5 5 0 Ankyrin repeat SPT6_acidic PF14632.6 EGG16762.1 - 0.0092 16.6 4.5 0.018 15.6 4.5 1.4 1 0 0 1 1 1 1 Acidic N-terminal SPT6 CCDC106 PF15794.5 EGG16762.1 - 0.032 14.0 3.3 0.061 13.0 3.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TerB_C PF15615.6 EGG16762.1 - 0.077 13.3 0.4 0.14 12.4 0.4 1.4 1 0 0 1 1 1 0 TerB-C domain Fimbrial_PilY2 PF14481.6 EGG16762.1 - 0.13 11.9 0.1 7.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 DUF2126 PF09899.9 EGG16762.1 - 0.28 9.2 0.9 0.39 8.7 0.9 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) YqfQ PF14181.6 EGG16762.1 - 5.3 7.2 9.1 3.6 7.7 6.8 1.9 2 0 0 2 2 2 0 YqfQ-like protein Ank_2 PF12796.7 EGG16764.1 - 3e-38 130.3 17.8 3.6e-09 37.1 0.2 7.9 4 1 3 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16764.1 - 8.6e-33 112.3 11.7 0.00079 19.9 0.0 12.6 10 3 3 14 14 14 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16764.1 - 1.2e-27 95.6 13.1 0.0029 17.9 0.1 14.4 6 1 10 16 16 16 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16764.1 - 2.9e-18 64.1 14.0 2.5 9.0 0.0 15.6 19 1 1 20 20 20 3 Ankyrin repeat DUF5049 PF16468.5 EGG16764.1 - 4.4e-06 26.5 16.9 60 3.7 0.0 12.1 8 3 7 15 15 15 0 Domain of unknown function (DUF5049) Ank PF00023.30 EGG16764.1 - 0.0023 18.3 12.8 67 4.2 0.1 10.4 7 2 3 10 10 10 0 Ankyrin repeat Baculo_LEF5_C PF11792.8 EGG16764.1 - 0.012 15.3 1.7 0.033 13.9 0.0 2.7 3 1 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain DUF1979 PF09322.10 EGG16764.1 - 0.1 12.5 0.0 11 6.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1979) Dynein_heavy PF03028.15 EGG16764.1 - 0.61 10.2 2.6 47 4.1 0.1 4.1 2 2 3 5 5 5 0 Dynein heavy chain region D6 P-loop domain SOR_SNZ PF01680.17 EGG16765.1 - 3.7e-110 366.6 9.1 4.9e-110 366.2 9.1 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EGG16765.1 - 6.2e-08 32.2 12.2 4e-07 29.6 0.9 2.7 1 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EGG16765.1 - 0.00014 21.0 0.4 0.076 12.1 0.0 2.8 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) IGPS PF00218.21 EGG16765.1 - 0.00098 18.4 0.1 0.56 9.3 0.0 2.2 2 0 0 2 2 2 2 Indole-3-glycerol phosphate synthase NanE PF04131.14 EGG16765.1 - 0.0017 17.5 2.4 0.072 12.3 0.0 3.0 2 1 1 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.24 EGG16765.1 - 0.0024 17.5 0.2 2.1 7.9 0.2 2.5 1 1 1 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family TetR_C_27 PF17935.1 EGG16765.1 - 0.0034 17.4 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain IMPDH PF00478.25 EGG16765.1 - 0.0083 15.2 0.4 0.011 14.8 0.4 1.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EGG16765.1 - 0.025 14.0 0.6 0.057 12.9 0.1 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein FMN_dh PF01070.18 EGG16765.1 - 0.035 13.1 0.7 0.23 10.5 0.0 2.2 3 0 0 3 3 3 0 FMN-dependent dehydrogenase NMO PF03060.15 EGG16765.1 - 0.13 11.6 6.4 0.38 10.1 0.4 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase DUF5615 PF18480.1 EGG16765.1 - 0.14 11.9 0.3 6.4 6.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) Lsm_C PF14894.6 EGG16765.1 - 5.1 6.9 6.1 22 4.9 0.1 3.3 3 1 1 4 4 4 0 Lsm C-terminal SNO PF01174.19 EGG16766.1 - 7.8e-47 159.6 0.5 9.7e-47 159.2 0.5 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGG16766.1 - 9.1e-09 35.2 0.1 1.7e-08 34.3 0.1 1.4 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EGG16766.1 - 0.032 14.0 0.6 0.29 10.9 0.6 2.1 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Ribosomal_L11_N PF03946.14 EGG16767.1 - 3e-19 68.6 0.6 5.2e-19 67.8 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGG16767.1 - 1.6e-15 57.3 0.5 3.3e-15 56.4 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Frag1 PF10277.9 EGG16768.1 - 1.6e-30 106.3 8.7 2.8e-16 59.7 0.1 2.0 1 1 1 2 2 2 2 Frag1/DRAM/Sfk1 family COX4 PF02936.14 EGG16768.1 - 0.035 14.1 0.1 0.061 13.3 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV zf-B_box PF00643.24 EGG16769.1 - 2.9e-15 56.1 15.8 2.6e-07 30.7 6.8 2.7 2 0 0 2 2 2 2 B-box zinc finger Sel1 PF08238.12 EGG16769.1 - 2.8e-06 27.8 0.1 2.7 8.8 0.0 4.1 4 0 0 4 4 4 3 Sel1 repeat zf-UBR PF02207.20 EGG16769.1 - 0.05 13.8 18.0 0.076 13.2 0.6 3.0 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) FYVE PF01363.21 EGG16769.1 - 1.4 9.2 12.2 1.4 9.1 0.8 2.6 1 1 1 2 2 2 0 FYVE zinc finger IBR PF01485.21 EGG16769.1 - 1.4 9.2 9.0 12 6.2 2.4 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Prok-RING_4 PF14447.6 EGG16769.1 - 2.6 8.0 12.4 9.9 6.1 6.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 LMBR1 PF04791.16 EGG16769.1 - 6 5.6 8.2 8.6 5.1 8.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribosomal_L33 PF00471.20 EGG16770.1 - 0.16 12.4 1.5 0.18 12.3 0.3 1.7 2 0 0 2 2 2 0 Ribosomal protein L33 DUF643 PF04867.12 EGG16771.1 - 0.0023 18.6 0.1 0.019 15.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF643) D_CNTX PF17492.2 EGG16771.1 - 8.1 6.7 12.5 36 4.6 2.0 3.4 3 0 0 3 3 3 0 Delta Ctenitoxins Ank_2 PF12796.7 EGG16772.1 - 3.9e-39 133.1 2.6 2.6e-07 31.1 0.0 7.5 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16772.1 - 1.2e-37 127.8 8.4 3e-05 24.5 0.0 11.5 8 5 1 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16772.1 - 4.4e-33 112.9 2.3 0.014 15.7 0.0 14.4 3 3 13 16 16 16 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16772.1 - 5.9e-24 81.5 0.3 2.8 8.8 0.0 14.0 14 1 1 15 15 15 4 Ankyrin repeat DUF5049 PF16468.5 EGG16772.1 - 5.6e-07 29.4 0.1 18 5.3 0.0 8.6 11 0 0 11 11 11 1 Domain of unknown function (DUF5049) Ank PF00023.30 EGG16772.1 - 0.00037 20.8 0.3 2.5e+02 2.4 0.0 8.3 7 3 2 9 9 9 0 Ankyrin repeat Sushi_2 PF09014.10 EGG16772.1 - 0.14 12.0 0.1 1.7 8.6 0.1 2.9 4 0 0 4 4 4 0 Beta-2-glycoprotein-1 fifth domain FBD PF08387.10 EGG16772.1 - 0.15 12.0 0.2 23 5.0 0.0 4.2 5 1 0 5 5 5 0 FBD GRP PF07172.11 EGG16773.1 - 0.17 12.5 23.6 0.22 12.2 23.6 1.1 1 0 0 1 1 1 0 Glycine rich protein family FoP_duplication PF13865.6 EGG16773.1 - 2.6 8.6 13.6 4.4 7.9 13.6 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Tim17 PF02466.19 EGG16775.1 - 2.3e-17 63.4 1.1 2.3e-17 63.4 1.1 2.4 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family zf-RING_2 PF13639.6 EGG16775.1 - 9.1e-12 45.1 10.3 9.1e-12 45.1 10.3 2.3 3 0 0 3 3 2 1 Ring finger domain zf-RING_11 PF17123.5 EGG16775.1 - 1.2e-09 37.7 3.9 1.2e-09 37.7 3.9 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGG16775.1 - 8.7e-08 31.9 6.0 8.7e-08 31.9 6.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG16775.1 - 1e-06 28.5 6.6 1e-06 28.5 6.6 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGG16775.1 - 1.8e-06 28.1 9.1 1.8e-06 28.1 9.1 2.2 2 1 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGG16775.1 - 4.1e-06 26.6 4.6 8.8e-06 25.5 4.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGG16775.1 - 2.7e-05 24.0 5.1 2.7e-05 24.0 5.1 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGG16775.1 - 5.8e-05 22.9 6.8 5.8e-05 22.9 6.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG16775.1 - 0.00018 21.5 1.8 0.00032 20.7 1.0 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGG16775.1 - 0.0038 17.2 2.9 0.011 15.8 2.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Med13_C PF06333.12 EGG16775.1 - 0.48 9.6 17.0 0.15 11.3 8.3 2.3 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Zn_ribbon_17 PF17120.5 EGG16775.1 - 0.55 9.9 6.4 1.5 8.5 6.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EGG16775.1 - 1.9 8.7 7.7 18 5.6 7.7 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain DUF4718 PF15842.5 EGG16775.1 - 4.2 7.1 6.4 9.7 5.9 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) IF4E PF01652.18 EGG16776.1 - 1.2e-52 177.9 2.2 1.7e-52 177.4 2.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Folate_carrier PF01770.18 EGG16776.1 - 0.98 8.1 2.0 1.4 7.6 2.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier Pirin PF02678.16 EGG16777.1 - 8.9e-36 122.2 0.5 2.7e-35 120.6 0.1 2.0 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 EGG16777.1 - 1.6e-26 92.7 0.0 6.6e-26 90.7 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Acyl_transf_1 PF00698.21 EGG16777.1 - 7.1e-25 88.2 0.1 1.7e-16 60.7 0.0 2.5 2 1 0 2 2 2 2 Acyl transferase domain KOW PF00467.29 EGG16777.1 - 0.051 13.5 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 KOW motif LRR_6 PF13516.6 EGG16778.1 - 3e-08 33.1 13.4 0.004 17.1 0.3 5.6 6 0 0 6 6 5 3 Leucine Rich repeat Med3 PF11593.8 EGG16778.1 - 0.00016 21.1 7.6 0.00026 20.3 7.6 1.4 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal EPL1 PF10513.9 EGG16778.1 - 0.019 15.4 2.3 0.03 14.7 2.3 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like Spt20 PF12090.8 EGG16778.1 - 0.02 14.5 20.0 0.037 13.6 20.0 1.4 1 0 0 1 1 1 0 Spt20 family F-box-like_2 PF13013.6 EGG16778.1 - 0.091 12.7 0.2 0.27 11.2 0.2 1.8 1 0 0 1 1 1 0 F-box-like domain Phostensin_N PF13916.6 EGG16778.1 - 0.13 12.6 3.9 0.23 11.8 3.9 1.3 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal LRR_1 PF00560.33 EGG16778.1 - 0.41 11.4 9.2 7 7.6 0.0 5.7 6 0 0 6 6 5 0 Leucine Rich Repeat Menin PF05053.13 EGG16778.1 - 0.71 8.2 7.1 0.92 7.8 7.1 1.1 1 0 0 1 1 1 0 Menin Mucin PF01456.17 EGG16778.1 - 0.89 9.5 11.6 1.9 8.5 11.6 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Androgen_recep PF02166.16 EGG16778.1 - 1.6 7.5 8.2 2.2 7.0 8.2 1.1 1 0 0 1 1 1 0 Androgen receptor MMR1 PF08505.10 EGG16778.1 - 2 8.7 17.5 3.1 8.0 17.5 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 EGG16778.1 - 2.7 7.9 16.5 3.9 7.4 16.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Stathmin PF00836.19 EGG16779.1 - 0.0034 17.3 13.9 0.0034 17.3 13.9 1.6 1 1 1 2 2 2 1 Stathmin family Ank_2 PF12796.7 EGG16780.1 - 1.1e-82 272.7 69.7 1.2e-08 35.4 0.1 22.2 14 6 11 26 26 26 21 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16780.1 - 6.1e-69 227.6 53.4 0.00023 21.7 0.0 29.4 27 5 6 33 33 33 18 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16780.1 - 1.6e-53 178.0 55.6 0.0013 19.0 0.0 35.1 16 7 22 40 40 40 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16780.1 - 1.4e-28 95.7 38.6 16 6.5 0.0 35.6 44 1 2 46 46 46 4 Ankyrin repeat DUF531 PF04407.12 EGG16780.1 - 0.00019 21.6 0.1 0.58 10.2 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF531) Ank PF00023.30 EGG16780.1 - 0.0055 17.1 17.3 1.7e+02 2.9 0.0 14.3 16 3 0 16 16 16 0 Ankyrin repeat Mur_ligase_C PF02875.21 EGG16780.1 - 0.25 11.6 1.3 25 5.2 0.0 3.6 4 0 0 4 4 4 0 Mur ligase family, glutamate ligase domain Ank_2 PF12796.7 EGG16782.1 - 5.3e-12 46.1 5.0 0.07 13.7 0.1 6.5 4 3 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16782.1 - 3.9e-09 36.9 2.6 0.12 13.0 0.0 6.9 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16782.1 - 6.5e-06 26.1 6.4 6.9 7.6 0.0 7.9 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 EGG16782.1 - 0.0017 18.6 3.4 6 7.3 0.1 6.0 9 0 0 9 9 9 1 Ankyrin repeats (many copies) Toprim_Crpt PF13342.6 EGG16782.1 - 0.095 12.7 0.0 0.37 10.8 0.0 2.0 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase Peptidase_C1 PF00112.23 EGG16783.1 - 5.5e-76 255.5 12.8 1.5e-61 208.2 5.5 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG16783.1 - 4.7e-13 49.4 1.2 7.6e-13 48.7 1.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGG16783.1 - 0.011 14.6 3.1 0.56 8.9 0.8 2.2 2 0 0 2 2 2 0 Peptidase C1-like family Hid1 PF12722.7 EGG16783.1 - 6.4 4.8 5.8 9.8 4.2 5.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOG2 PF10428.9 EGG16783.1 - 7.8 5.6 25.1 11 5.1 25.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_S28 PF05577.12 EGG16784.1 - 6.8e-83 278.9 0.0 1.2e-82 278.0 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 EGG16784.1 - 0.0011 18.7 0.3 0.0023 17.6 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG16784.1 - 0.0042 17.7 0.1 0.01 16.4 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGG16784.1 - 0.0096 15.4 0.3 0.06 12.8 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2920 PF11144.8 EGG16784.1 - 0.014 14.6 0.1 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Peptidase_S37 PF05576.11 EGG16784.1 - 0.032 12.9 0.0 0.05 12.3 0.0 1.3 1 0 0 1 1 1 0 PS-10 peptidase S37 Hydrolase_4 PF12146.8 EGG16784.1 - 0.033 13.4 0.0 0.079 12.2 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 EMP70 PF02990.16 EGG16785.1 - 3.6e-36 124.9 18.2 6e-36 124.2 18.2 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 TMEM154 PF15102.6 EGG16785.1 - 4.2 7.3 4.9 7.2 6.5 0.0 3.3 4 0 0 4 4 4 0 TMEM154 protein family Ank_2 PF12796.7 EGG16787.1 - 2.5e-26 92.1 10.4 5.1e-11 43.0 0.1 5.4 3 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG16787.1 - 1.5e-20 73.0 5.3 0.00086 19.6 0.0 9.0 5 3 4 10 10 10 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG16787.1 - 1.4e-19 70.1 6.1 2.6e-05 24.7 0.0 9.0 7 3 3 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16787.1 - 4.9e-15 54.1 1.6 1 10.2 0.0 10.1 12 1 1 13 13 13 4 Ankyrin repeat Ank PF00023.30 EGG16787.1 - 1.3e-05 25.4 1.0 1e+02 3.6 0.1 7.5 6 1 1 7 7 7 0 Ankyrin repeat DUF5049 PF16468.5 EGG16787.1 - 6.3e-05 22.8 0.6 25 4.9 0.0 6.0 5 1 1 6 6 6 0 Domain of unknown function (DUF5049) DUF4878 PF12870.7 EGG16787.1 - 0.0068 16.7 0.2 0.089 13.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4878) DUF3447 PF11929.8 EGG16787.1 - 1.6 8.7 8.8 2.2 8.3 0.1 4.5 3 2 1 4 4 4 0 Domain of unknown function (DUF3447) VCBS PF13517.6 EGG16788.1 - 2.4e-17 63.3 19.0 6e-08 33.2 1.5 6.4 6 1 0 6 6 6 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGG16788.1 - 1.2e-12 47.7 8.2 0.00065 19.8 0.5 5.7 5 0 0 5 5 5 4 FG-GAP repeat PQQ PF01011.21 EGG16788.1 - 0.00018 21.3 0.2 4.7 7.3 0.0 4.5 4 0 0 4 4 4 2 PQQ enzyme repeat BBS2_Mid PF14783.6 EGG16788.1 - 0.00043 20.3 2.7 1.2 9.2 0.0 5.3 6 1 1 7 7 7 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 EGG16788.1 - 0.0006 19.5 0.0 0.0038 16.8 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain TcdB_toxin_midN PF12256.8 EGG16788.1 - 0.00092 18.6 1.7 0.95 8.8 0.0 4.6 5 0 0 5 5 5 1 Insecticide toxin TcdB middle/N-terminal region Itfg2 PF15907.5 EGG16788.1 - 0.0057 15.7 8.0 6.7 5.6 0.1 5.9 6 1 1 7 7 7 1 Integrin-alpha FG-GAP repeat-containing protein 2 PliI PF16743.5 EGG16788.1 - 0.011 15.5 0.5 26 4.6 0.0 4.7 4 1 1 5 5 5 0 Periplasmic lysozyme inhibitor of I-type lysozyme BBS2_C PF14782.6 EGG16788.1 - 0.017 13.9 0.0 5.1 5.7 0.0 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal PQQ_3 PF13570.6 EGG16788.1 - 0.025 15.1 11.9 35 5.1 0.0 6.2 7 0 0 7 7 5 0 PQQ-like domain DUF3216 PF11505.8 EGG16788.1 - 0.2 11.9 0.0 0.74 10.0 0.0 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3216) BBS1 PF14779.6 EGG16788.1 - 0.27 10.6 0.9 15 4.9 0.0 3.8 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 1 zf-C3HC4_3 PF13920.6 EGG16789.1 - 4.6e-10 39.2 8.3 6.8e-10 38.7 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG16789.1 - 4.5e-08 32.8 10.2 7.5e-08 32.1 10.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 K-box PF01486.17 EGG16789.1 - 0.00084 19.5 6.9 0.00084 19.5 6.9 2.6 1 1 1 2 2 2 1 K-box region zf-RING_2 PF13639.6 EGG16789.1 - 0.008 16.5 12.9 0.013 15.8 12.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_14 PF17978.1 EGG16789.1 - 0.025 15.0 2.6 0.058 13.8 2.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TerY_C PF15616.6 EGG16789.1 - 0.027 14.6 3.5 0.053 13.6 3.1 1.6 1 1 0 1 1 1 0 TerY-C metal binding domain Baculo_PEP_C PF04513.12 EGG16789.1 - 0.72 9.9 5.9 0.7 9.9 0.7 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 EGG16789.1 - 0.87 7.5 13.1 1 7.2 13.1 1.0 1 0 0 1 1 1 0 Prominin HSCB_C PF07743.13 EGG16789.1 - 1.7 9.2 12.2 0.22 12.0 5.3 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain NPV_P10 PF05531.12 EGG16789.1 - 3.4 8.2 7.2 5.8 7.5 0.2 2.5 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HTH_WhiA PF02650.14 EGG16789.1 - 5 7.5 12.9 1.1 9.7 2.3 2.9 2 1 1 3 3 3 0 WhiA C-terminal HTH domain Sec15 PF04091.12 EGG16790.1 - 0.022 14.2 2.5 0.028 13.8 2.5 1.1 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like MDD_C PF18376.1 EGG16790.1 - 0.069 12.9 0.4 0.1 12.3 0.1 1.5 2 0 0 2 2 2 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain zf-C3HC4_3 PF13920.6 EGG16791.1 - 1.3e-14 53.8 22.5 7.9e-11 41.7 13.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG16791.1 - 2.8e-09 36.7 22.3 1.2e-06 28.3 13.6 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 K-box PF01486.17 EGG16791.1 - 0.00098 19.3 24.1 0.0033 17.6 1.2 4.9 4 1 1 5 5 5 2 K-box region Nucleoporin_FG PF13634.6 EGG16791.1 - 0.48 11.3 71.4 7.9 7.4 26.3 4.0 1 1 2 3 3 3 0 Nucleoporin FG repeat region zf-C3HC4_3 PF13920.6 EGG16792.1 - 4.1e-12 45.8 12.8 8e-12 44.8 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG16792.1 - 2.3e-08 33.8 13.1 5e-08 32.7 13.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF2000 PF09391.10 EGG16792.1 - 0.0013 18.7 0.2 0.0051 16.7 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2000) zf-RING_5 PF14634.6 EGG16792.1 - 0.01 15.8 13.6 0.032 14.2 13.6 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EGG16792.1 - 0.028 14.8 14.3 0.068 13.5 14.3 1.7 1 0 0 1 1 1 0 Ring finger domain CotJB PF12652.7 EGG16792.1 - 0.13 12.5 3.9 3.3 8.0 0.3 2.7 2 2 0 2 2 2 0 CotJB protein Kinesin_assoc PF16183.5 EGG16792.1 - 6.8 6.8 9.2 24 5.0 9.2 2.0 1 1 0 1 1 1 0 Kinesin-associated PAC4 PF16093.5 EGG16793.1 - 7.3e-08 32.5 0.2 1.1e-07 32.0 0.2 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Mucin PF01456.17 EGG16794.1 - 0.02 14.9 30.5 0.057 13.4 30.5 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein RIFIN PF02009.16 EGG16794.1 - 0.29 11.0 5.9 0.086 12.7 2.3 1.8 2 0 0 2 2 2 0 Rifin Presenilin PF01080.17 EGG16795.1 - 0.23 10.2 6.1 0.46 9.2 6.1 1.4 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 EGG16795.1 - 6.8 6.2 5.6 14 5.2 5.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3430 PF11912.8 EGG16796.1 - 2.5e-05 24.5 8.4 2.5e-05 24.5 8.4 4.6 3 2 1 4 4 4 2 Protein of unknown function (DUF3430) T_cell_tran_alt PF15128.6 EGG16796.1 - 0.024 14.4 0.5 10 6.0 0.0 2.7 2 0 0 2 2 2 0 T-cell leukemia translocation-altered SPX PF03105.19 EGG16796.1 - 4.7 7.0 15.1 5.9 6.7 4.7 2.1 2 0 0 2 2 2 0 SPX domain DUF3591 PF12157.8 EGG16797.1 - 3.3e-145 484.1 1.5 8.4e-145 482.8 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 EGG16797.1 - 1.9e-14 53.5 1.0 8.5e-14 51.4 1.0 2.2 1 0 0 1 1 1 1 Bromodomain TBP-binding PF09247.11 EGG16797.1 - 3.2e-09 36.9 2.6 3.2e-09 36.9 2.6 2.1 2 0 0 2 2 2 1 TATA box-binding protein binding GATA PF00320.27 EGG16798.1 - 2.3e-12 46.3 5.2 5.5e-12 45.1 5.2 1.7 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 EGG16798.1 - 0.0036 17.4 0.1 0.0083 16.2 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Tma16 PF11176.8 EGG16798.1 - 1.6 8.6 9.7 14 5.5 6.7 3.0 2 1 0 2 2 2 0 Translation machinery-associated protein 16 V_ATPase_I PF01496.19 EGG16798.1 - 7 4.4 5.6 0.56 8.1 0.2 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Peptidase_A24 PF01478.18 EGG16799.1 - 0.14 12.5 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Type IV leader peptidase family HSP20 PF00011.21 EGG16801.1 - 4.7e-19 68.4 0.3 1.7e-18 66.6 0.0 2.1 3 0 0 3 3 3 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG16801.1 - 7.9e-11 41.4 0.0 1.8e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Ank_2 PF12796.7 EGG16802.1 - 8.7e-38 128.8 18.8 6.4e-07 29.9 0.0 8.3 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16802.1 - 2e-28 98.4 16.0 8.6e-06 26.2 0.1 11.5 6 5 5 13 13 13 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16802.1 - 1e-21 76.7 11.0 0.031 14.6 0.0 12.4 5 3 9 14 14 14 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16802.1 - 1.4e-21 74.2 7.1 1.9 9.3 0.0 14.4 15 2 2 17 17 17 4 Ankyrin repeat DUF5049 PF16468.5 EGG16802.1 - 1.8e-12 47.0 7.9 0.082 12.8 0.0 10.0 9 2 3 12 12 12 4 Domain of unknown function (DUF5049) Ank PF00023.30 EGG16802.1 - 0.00015 22.0 2.4 28 5.4 0.0 7.7 7 2 1 8 8 8 0 Ankyrin repeat DUF3447 PF11929.8 EGG16802.1 - 0.0081 16.1 12.4 0.46 10.5 0.1 6.4 4 1 3 7 7 7 1 Domain of unknown function (DUF3447) SQS_PSY PF00494.19 EGG16803.1 - 4.7e-41 141.0 0.0 6.1e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SWI-SNF_Ssr4 PF08549.10 EGG16803.1 - 0.081 11.5 8.6 0.11 11.1 8.6 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Zip PF02535.22 EGG16803.1 - 6 6.0 6.6 8.1 5.6 6.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_A_bac PF01000.26 EGG16804.1 - 6.8e-35 119.8 0.4 5e-33 113.8 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGG16804.1 - 1.1e-23 82.4 0.0 1.5e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.7 EGG16804.1 - 0.0091 16.6 1.8 0.0091 16.6 1.8 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGG16804.1 - 0.25 11.5 9.5 0.1 12.8 1.3 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 EGG16804.1 - 2.5 8.1 6.6 2.7 7.9 0.7 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain ABC_tran PF00005.27 EGG16805.1 - 3.5e-17 63.2 0.4 2.2e-16 60.6 0.0 2.5 2 2 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 EGG16805.1 - 0.00034 21.0 0.0 0.00098 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EGG16805.1 - 0.0005 20.6 7.4 0.046 14.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 EGG16805.1 - 0.0012 18.1 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EGG16805.1 - 0.0013 18.6 0.1 0.0031 17.5 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGG16805.1 - 0.0016 18.1 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 EGG16805.1 - 0.0065 16.4 0.5 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 EGG16805.1 - 0.022 14.7 0.0 0.049 13.6 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EGG16805.1 - 0.048 13.9 0.4 0.41 10.9 0.1 2.6 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGG16805.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 EGG16805.1 - 0.064 13.0 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGG16805.1 - 0.083 12.3 0.3 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 EGG16805.1 - 0.088 13.2 0.0 0.57 10.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TFIIE-A_C PF11521.8 EGG16805.1 - 0.4 11.0 7.0 1.5 9.2 7.0 2.1 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Myc_N PF01056.18 EGG16805.1 - 0.57 10.0 10.9 0.093 12.6 7.1 1.5 2 0 0 2 2 2 0 Myc amino-terminal region AAA_18 PF13238.6 EGG16805.1 - 0.58 10.7 5.0 8.6 6.9 0.0 3.0 3 1 0 3 3 3 0 AAA domain CDC37_C PF08564.10 EGG16806.1 - 0.044 13.9 0.6 0.2 11.8 0.2 2.3 2 0 0 2 2 2 0 Cdc37 C terminal domain DASH_Dad4 PF08650.10 EGG16806.1 - 0.18 11.8 1.0 1.1 9.3 0.2 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad4 DNA_alkylation PF08713.11 EGG16807.1 - 7.8e-58 195.7 0.3 9.4e-58 195.4 0.3 1.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme UCH PF00443.29 EGG16808.1 - 3.4e-37 128.3 2.7 8.4e-37 127.1 2.7 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EGG16808.1 - 1.6e-19 69.4 0.0 7.2e-19 67.3 0.0 2.1 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 EGG16808.1 - 1.1e-16 60.9 0.5 4.4e-16 58.9 0.0 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGG16808.1 - 1.4e-15 57.7 0.4 2.5e-15 56.9 0.4 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 EGG16808.1 - 1.3e-14 53.7 0.1 1.5e-08 34.4 0.0 3.0 2 1 0 2 2 2 2 UBA/TS-N domain BNIP3 PF06553.12 EGG16808.1 - 0.047 13.4 0.4 0.41 10.3 0.0 2.5 2 0 0 2 2 2 0 BNIP3 SR-25 PF10500.9 EGG16808.1 - 1.4 8.5 4.5 2.5 7.7 4.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Response_reg PF00072.24 EGG16809.1 - 2.7e-20 72.6 0.6 6.4e-20 71.4 0.2 1.8 2 0 0 2 2 2 1 Response regulator receiver domain LRR_6 PF13516.6 EGG16809.1 - 3.3e-09 36.1 24.1 0.11 12.6 0.2 7.6 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 EGG16809.1 - 0.0067 16.8 9.5 0.014 15.8 1.7 6.3 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG16809.1 - 0.0084 15.8 28.8 0.17 11.7 7.4 4.3 2 2 2 4 4 4 4 Leucine rich repeat DUF2981 PF11200.8 EGG16809.1 - 1 9.0 5.2 1.6 8.4 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Macoilin PF09726.9 EGG16809.1 - 1.3 7.5 11.6 1.5 7.3 11.6 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 EGG16809.1 - 4 6.9 8.0 6.5 6.2 8.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CSN8_PSD8_EIF3K PF10075.9 EGG16810.1 - 1.5e-14 54.2 0.3 4.8e-10 39.6 0.1 2.3 2 0 0 2 2 2 2 CSN8/PSMD8/EIF3K family Ank_4 PF13637.6 EGG16811.1 - 6.2e-21 74.5 3.9 4e-10 40.0 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16811.1 - 8e-21 73.8 3.3 4.5e-11 42.8 0.4 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG16811.1 - 6.4e-18 65.1 5.7 4.4e-13 49.6 1.5 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG16811.1 - 2.4e-11 42.8 0.4 0.00032 20.9 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EGG16811.1 - 4.7e-10 39.5 0.7 0.00017 21.9 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Dus PF01207.17 EGG16812.1 - 1.8e-67 227.7 0.0 2.4e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 EGG16812.1 - 0.0018 17.6 0.0 0.0036 16.7 0.0 1.6 1 1 0 1 1 1 1 Thiamine monophosphate synthase DUF561 PF04481.12 EGG16812.1 - 0.082 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) His_biosynth PF00977.21 EGG16812.1 - 0.11 12.0 0.0 0.37 10.2 0.0 1.8 1 1 1 2 2 2 0 Histidine biosynthesis protein Ank_2 PF12796.7 EGG16813.1 - 2.7e-07 31.1 0.0 2.5 8.8 0.0 6.1 5 2 3 8 8 8 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG16813.1 - 6.4e-07 29.2 0.0 33 5.5 0.0 7.9 8 0 0 8 8 8 1 Ankyrin repeat Ank_4 PF13637.6 EGG16813.1 - 7.7e-07 29.5 0.3 9.4 7.0 0.0 7.0 6 2 1 7 7 7 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16813.1 - 0.00043 20.5 0.0 0.26 11.7 0.0 4.9 7 0 0 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16814.1 - 0.13 12.9 0.1 8.9 7.2 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeat Vac14_Fab1_bd PF12755.7 EGG16815.1 - 0.00043 20.8 0.3 0.0037 17.8 0.0 2.7 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGG16815.1 - 0.00095 19.2 0.0 0.39 11.1 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat DUF816 PF05674.12 EGG16815.1 - 0.028 14.4 0.1 0.091 12.7 0.1 2.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Lipase_3 PF01764.25 EGG16816.1 - 1.5e-24 86.5 0.0 2.7e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) CBM49 PF09478.10 EGG16816.1 - 3.9e-06 27.1 0.1 1.4e-05 25.3 0.1 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF2974 PF11187.8 EGG16816.1 - 0.0012 18.5 0.7 0.0069 16.0 0.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EGG16816.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ank_4 PF13637.6 EGG16819.1 - 0.024 15.2 0.1 9.1 7.0 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG16819.1 - 0.026 15.1 0.0 20 5.8 0.0 3.4 3 1 1 4 4 4 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG16819.1 - 0.047 14.0 0.0 4.3 7.8 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) CRM1_C PF08767.11 EGG16820.1 - 3.3e-107 358.4 11.9 3.3e-107 358.4 11.9 3.3 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 EGG16820.1 - 3.2e-34 118.1 4.6 3.2e-34 118.1 4.6 4.1 5 1 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EGG16820.1 - 7.2e-31 105.6 1.8 2.6e-30 103.9 1.8 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EGG16820.1 - 4.4e-25 87.5 1.1 4.4e-25 87.5 1.1 3.2 4 0 0 4 4 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EGG16820.1 - 5.4e-19 67.4 1.9 1e-18 66.5 0.9 2.1 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EGG16820.1 - 5.8e-14 51.8 0.6 2.3e-13 49.9 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EGG16820.1 - 0.0027 17.6 7.0 0.036 14.0 0.1 5.1 6 0 0 6 6 6 1 Domain of unknown function (DUF3385) UCH PF00443.29 EGG16820.1 - 0.0095 15.5 0.9 0.041 13.4 0.0 2.5 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Vac14_Fab1_bd PF12755.7 EGG16820.1 - 0.038 14.6 0.3 3.4 8.3 0.0 3.6 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.8 EGG16820.1 - 0.32 11.1 5.3 0.31 11.2 0.1 3.7 4 0 0 4 4 3 0 V-ATPase subunit H 7TMR-HDED PF07697.11 EGG16820.1 - 0.34 11.0 2.7 4.7 7.3 0.4 3.3 3 0 0 3 3 3 0 7TM-HD extracellular ABC_tran PF00005.27 EGG16821.1 - 2.6e-16 60.4 0.0 2.6e-16 60.4 0.0 2.2 2 1 0 2 2 1 1 ABC transporter ABC_membrane_2 PF06472.15 EGG16821.1 - 9.6e-12 44.9 6.0 7e-07 28.9 0.9 2.3 1 1 1 2 2 2 2 ABC transporter transmembrane region 2 DUF815 PF05673.13 EGG16821.1 - 8.4e-05 21.8 0.1 0.00018 20.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EGG16821.1 - 0.00057 20.3 0.0 0.0018 18.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGG16821.1 - 0.0025 17.5 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG16821.1 - 0.0037 17.2 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 EGG16821.1 - 0.0094 15.9 0.9 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 EGG16821.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 EGG16821.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.21 EGG16821.1 - 0.12 11.7 0.3 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 EGG16821.1 - 0.13 12.8 0.0 0.13 12.8 0.0 3.4 3 1 0 3 3 2 0 AAA domain Synaptobrevin PF00957.21 EGG16822.1 - 2.3e-09 36.9 0.3 3.9e-09 36.2 0.3 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGG16822.1 - 0.00057 19.9 0.0 0.00094 19.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Gp-FAR-1 PF05823.12 EGG16822.1 - 0.024 15.0 0.2 0.039 14.3 0.2 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF5089 PF17002.5 EGG16822.1 - 0.032 14.1 0.6 0.058 13.3 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) Cpn60_TCP1 PF00118.24 EGG16823.1 - 9.2e-157 522.6 13.5 1e-156 522.4 13.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family adh_short PF00106.25 EGG16824.1 - 3.9e-48 163.5 0.1 5.6e-48 163.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG16824.1 - 6e-47 160.2 0.0 7.5e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG16824.1 - 1.4e-08 34.8 0.1 2.2e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EGG16824.1 - 0.0015 19.1 0.1 0.0033 18.0 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EGG16824.1 - 0.0029 17.8 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 EGG16824.1 - 0.0036 16.7 0.0 0.0049 16.3 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 EGG16824.1 - 0.019 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGG16824.1 - 0.035 14.3 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.19 EGG16824.1 - 0.047 12.7 0.1 0.078 12.0 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Lycopene_cycl PF05834.12 EGG16824.1 - 0.084 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Epimerase PF01370.21 EGG16824.1 - 0.15 11.5 0.0 2.2 7.7 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family CKS PF01111.19 EGG16825.1 - 4.8e-33 113.2 0.4 5.4e-33 113.1 0.4 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit UPF0113_N PF17833.1 EGG16826.1 - 2.2e-29 101.8 2.7 3.3e-29 101.3 2.7 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EGG16826.1 - 1.6e-22 79.5 0.0 2.7e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 EGG16826.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 PUA domain Ribosomal_L36e PF01158.18 EGG16827.1 - 1.7e-27 95.5 1.5 1.7e-27 95.5 1.5 2.9 3 1 0 3 3 3 1 Ribosomal protein L36e Thioredoxin PF00085.20 EGG16827.1 - 1.2e-17 63.8 0.0 4e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin SRP-alpha_N PF04086.13 EGG16827.1 - 0.23 11.4 40.2 0.46 10.4 40.2 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Dapper PF15268.6 EGG16827.1 - 1.2 7.9 48.8 1.6 7.5 48.8 1.1 1 0 0 1 1 1 0 Dapper LAP1C PF05609.12 EGG16827.1 - 9 5.3 43.0 17 4.3 43.0 1.5 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Arf PF00025.21 EGG16828.1 - 1.3e-65 220.2 0.0 1.6e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG16828.1 - 2.5e-14 53.5 0.0 5.4e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG16828.1 - 3e-13 49.7 0.0 4e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGG16828.1 - 1.1e-11 44.6 0.0 2.4e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGG16828.1 - 8.1e-11 41.7 3.6 1.7e-08 34.0 0.3 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGG16828.1 - 1.9e-09 37.2 0.0 3.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG16828.1 - 1.8e-05 24.8 0.0 3.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.14 EGG16828.1 - 0.046 13.6 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Phospholip_B PF04916.13 EGG16829.1 - 3.3e-170 567.2 12.6 4e-170 566.9 12.6 1.0 1 0 0 1 1 1 1 Phospholipase B GRP PF07172.11 EGG16830.1 - 0.0003 21.4 18.4 0.0015 19.2 4.6 2.4 2 0 0 2 2 2 2 Glycine rich protein family Keratin_2_head PF16208.5 EGG16830.1 - 0.017 15.2 39.2 0.14 12.3 11.0 2.3 2 0 0 2 2 2 0 Keratin type II head zf-RING_4 PF14570.6 EGG16832.1 - 3.5e-09 36.3 11.9 6.5e-09 35.4 11.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 EGG16832.1 - 4.2e-07 29.7 0.0 1.2e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.12 EGG16832.1 - 0.0009 18.7 1.6 0.0009 18.7 1.6 5.5 5 1 0 5 5 5 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 EGG16832.1 - 1.7 8.6 7.8 3.5 7.5 7.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Arm PF00514.23 EGG16833.1 - 1.6e-07 31.1 0.5 0.0071 16.4 0.0 5.7 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat DUF3572 PF12096.8 EGG16833.1 - 0.091 13.0 0.0 0.72 10.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3572) DUF3027 PF11228.8 EGG16833.1 - 0.11 12.5 0.1 0.88 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) PhyH PF05721.13 EGG16834.1 - 1.1e-09 38.9 0.0 2.5e-08 34.5 0.0 2.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.16 EGG16834.1 - 0.098 12.4 0.0 19 4.9 0.0 2.5 2 1 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family Ank_2 PF12796.7 EGG16835.1 - 5.8e-16 58.9 1.2 0.021 15.4 0.0 7.2 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16835.1 - 9.1e-13 48.4 1.6 0.15 12.7 0.1 9.0 8 2 0 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16835.1 - 2e-08 33.9 7.9 30 5.6 0.0 10.6 11 1 1 12 12 12 1 Ankyrin repeat FBD PF08387.10 EGG16835.1 - 0.059 13.3 0.0 34 4.4 0.0 3.5 3 0 0 3 3 3 0 FBD Mito_fiss_reg PF05308.11 EGG16836.1 - 0.0064 16.6 8.2 0.0099 16.0 8.2 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator Peptidase_M13_N PF05649.13 EGG16836.1 - 0.011 15.4 0.6 0.015 15.0 0.6 1.1 1 0 0 1 1 1 0 Peptidase family M13 UPF0240 PF06784.11 EGG16838.1 - 0.033 14.3 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) FSAP_sig_propep PF03032.15 EGG16841.1 - 0.091 12.8 0.3 0.091 12.8 0.3 1.1 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide Gcd10p PF04189.13 EGG16842.1 - 1.7e-59 201.4 4.3 1.7e-59 201.4 4.3 1.9 2 0 0 2 2 2 1 Gcd10p family Ank_4 PF13637.6 EGG16843.1 - 3.7e-15 56.1 0.1 5.9e-08 33.1 0.1 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGG16843.1 - 4e-12 46.0 0.8 1.9e-08 34.4 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGG16843.1 - 7.3e-12 45.3 1.6 2.7e-07 30.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG16843.1 - 1.3e-09 38.5 0.1 4e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG16843.1 - 5.7e-08 32.4 0.6 0.00045 20.5 0.0 4.3 3 0 0 3 3 3 1 Ankyrin repeat RA PF00788.23 EGG16843.1 - 6.1e-08 33.2 0.1 1.5e-07 31.9 0.1 1.7 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Erf4 PF10256.9 EGG16845.1 - 3.1e-05 24.1 0.0 8.9e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Spo7 PF03907.13 EGG16845.1 - 0.034 13.6 0.1 0.034 13.6 0.1 1.6 2 0 0 2 2 2 0 Spo7-like protein DUF1724 PF08350.10 EGG16845.1 - 0.051 13.7 0.4 0.41 10.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1724) OppC_N PF12911.7 EGG16845.1 - 0.14 12.1 1.0 0.27 11.2 0.5 1.7 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C cobW PF02492.19 EGG16846.1 - 6e-05 22.7 8.0 0.014 15.0 1.0 3.2 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGG16846.1 - 0.062 13.2 0.0 0.25 11.3 0.0 2.0 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain C_tripleX PF02363.19 EGG16848.1 - 0.21 11.9 12.5 5.8e+02 1.2 12.5 2.7 1 1 0 1 1 1 0 Cysteine rich repeat Ras PF00071.22 EGG16849.1 - 3.4e-64 215.3 0.7 4.1e-64 215.1 0.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG16849.1 - 2.4e-36 124.6 0.1 3.9e-36 123.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG16849.1 - 6.1e-16 58.4 0.1 7.4e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG16849.1 - 2.2e-06 27.2 0.1 2.7e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGG16849.1 - 1.2e-05 25.0 0.5 2.8e-05 23.7 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGG16849.1 - 6e-05 23.0 0.9 0.14 12.1 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGG16849.1 - 0.0001 22.3 0.0 0.00018 21.6 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGG16849.1 - 0.00094 18.7 0.1 0.0013 18.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 EGG16849.1 - 0.039 13.7 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGG16849.1 - 0.061 13.6 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG16849.1 - 0.064 13.6 0.0 0.093 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EGG16849.1 - 0.065 12.7 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 EGG16849.1 - 0.088 13.2 0.0 0.44 11.0 0.0 1.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EGG16849.1 - 0.091 12.5 0.2 0.43 10.3 0.2 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EGG16849.1 - 0.095 12.7 0.0 0.17 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 EGG16849.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 EGG16849.1 - 0.19 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain UQ_con PF00179.26 EGG16851.1 - 3.2e-46 156.4 0.0 3.6e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGG16851.1 - 0.00099 18.8 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGG16851.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 1 0 1 1 1 0 UEV domain NAPRTase_N PF17767.1 EGG16852.1 - 5.7e-36 123.7 0.0 1.9e-35 122.0 0.0 1.9 3 0 0 3 3 3 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 EGG16852.1 - 7.8e-36 122.9 0.0 1.3e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 EGG16852.1 - 4.3e-08 33.1 0.0 7.2e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family F-box PF00646.33 EGG16853.1 - 0.05 13.5 0.2 0.18 11.7 0.2 2.0 1 0 0 1 1 1 0 F-box domain TPR_2 PF07719.17 EGG16854.1 - 2.9e-39 130.0 41.4 1e-05 25.2 0.1 16.3 19 0 0 19 19 16 10 Tetratricopeptide repeat TPR_19 PF14559.6 EGG16854.1 - 2.5e-35 120.8 20.7 2.5e-06 27.9 0.1 11.4 9 3 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 EGG16854.1 - 8.1e-34 114.1 44.0 9.3e-06 25.2 0.1 15.8 17 0 0 17 17 16 7 Tetratricopeptide repeat TPR_16 PF13432.6 EGG16854.1 - 3.4e-32 110.8 2.9 3.2e-06 27.7 0.0 9.5 8 2 3 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGG16854.1 - 5.2e-32 107.8 0.5 0.00058 20.5 0.0 12.9 8 4 7 15 15 12 8 Tetratricopeptide repeat TPR_12 PF13424.6 EGG16854.1 - 6.1e-30 103.3 23.6 1.5e-07 31.6 0.1 11.7 7 2 6 13 13 13 7 Tetratricopeptide repeat TPR_8 PF13181.6 EGG16854.1 - 2.8e-28 95.7 32.7 0.00078 19.5 0.1 14.9 15 1 0 15 15 14 7 Tetratricopeptide repeat TPR_11 PF13414.6 EGG16854.1 - 7.3e-25 86.4 35.9 7.6e-05 22.3 0.7 12.6 9 4 4 13 13 13 6 TPR repeat TPR_17 PF13431.6 EGG16854.1 - 7.2e-23 79.3 37.2 0.026 14.9 0.1 15.0 17 0 0 17 17 15 8 Tetratricopeptide repeat TPR_7 PF13176.6 EGG16854.1 - 2.3e-21 74.2 13.5 0.002 18.0 0.0 12.8 15 0 0 15 15 13 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGG16854.1 - 3.6e-19 68.0 16.3 0.00067 20.1 0.1 9.9 10 0 0 10 10 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG16854.1 - 2e-15 56.8 26.3 0.0016 18.6 2.0 7.8 5 3 3 8 8 8 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EGG16854.1 - 3.1e-13 49.8 3.8 0.0057 16.1 0.0 6.1 3 2 2 5 5 5 4 MalT-like TPR region TPR_10 PF13374.6 EGG16854.1 - 2e-12 46.5 16.3 0.42 10.5 0.0 11.3 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGG16854.1 - 3.5e-12 46.3 0.0 0.016 15.3 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.8 EGG16854.1 - 1.6e-05 24.1 4.5 1.6e-05 24.1 4.5 7.1 5 3 2 7 7 4 1 NMDA receptor-regulated protein 1 Rapsyn_N PF10579.9 EGG16854.1 - 2.6e-05 24.2 1.1 0.099 12.8 0.0 3.9 4 0 0 4 4 3 1 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.6 EGG16854.1 - 3.1e-05 23.9 8.2 0.12 12.5 0.0 4.9 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 EGG16854.1 - 0.00027 20.9 7.8 3.4 7.8 0.0 6.1 5 0 0 5 5 4 1 Tetratricopeptide repeat PSD5 PF07637.11 EGG16854.1 - 0.0052 17.1 0.0 2.7 8.4 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1595) TPR_4 PF07721.14 EGG16854.1 - 0.013 16.0 0.0 1.4e+02 3.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DELLA PF12041.8 EGG16854.1 - 0.017 15.0 0.1 10 6.1 0.0 3.1 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal TFIIA PF03153.13 EGG16854.1 - 0.042 13.8 36.0 0.1 12.5 36.0 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RF-1 PF00472.20 EGG16855.1 - 0.0024 17.8 0.1 0.0039 17.1 0.1 1.2 1 0 0 1 1 1 1 RF-1 domain Fungal_lectin_2 PF18647.1 EGG16855.1 - 0.03 14.8 0.2 0.046 14.2 0.2 1.3 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin MRP-S28 PF10213.9 EGG16855.1 - 0.083 13.3 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Sugar_tr PF00083.24 EGG16856.1 - 4.6e-83 279.6 15.5 2.2e-41 142.2 0.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGG16856.1 - 6.9e-23 81.1 32.2 5.9e-13 48.5 5.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGG16856.1 - 0.00012 20.7 7.9 0.028 12.8 1.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 EGG16856.1 - 0.66 10.6 4.0 0.37 11.3 0.6 2.2 2 0 0 2 2 2 0 Phage holin family 2 NST1 PF13945.6 EGG16857.1 - 3.1 7.8 14.2 4 7.5 14.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator F-box-like PF12937.7 EGG16858.1 - 0.11 12.4 2.0 0.32 10.9 0.5 2.6 2 1 0 2 2 2 0 F-box-like Spt20 PF12090.8 EGG16859.1 - 0.0012 18.5 7.7 0.0013 18.4 7.7 1.1 1 0 0 1 1 1 1 Spt20 family SUIM_assoc PF16619.5 EGG16859.1 - 0.0041 17.1 8.6 0.007 16.4 8.6 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 EGG16859.1 - 0.038 13.2 8.6 0.042 13.1 8.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4834 PF16118.5 EGG16859.1 - 0.094 13.7 2.3 0.13 13.3 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) UPF0697 PF15117.6 EGG16859.1 - 0.11 12.5 4.5 0.15 12.1 3.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 Androgen_recep PF02166.16 EGG16859.1 - 0.34 9.7 7.1 0.33 9.8 7.1 1.1 1 0 0 1 1 1 0 Androgen receptor MTP18 PF10558.9 EGG16859.1 - 0.38 10.7 1.5 0.48 10.4 1.5 1.1 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) DivIC PF04977.15 EGG16859.1 - 0.46 10.3 7.0 1 9.2 7.0 1.5 1 0 0 1 1 1 0 Septum formation initiator DnaJ_CXXCXGXG PF00684.19 EGG16859.1 - 2.4 8.6 10.1 1.4 9.4 8.3 1.5 1 1 0 1 1 1 0 DnaJ central domain FHA PF00498.26 EGG16860.1 - 1.6e-10 41.1 0.1 4e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 FHA domain AA_permease_2 PF13520.6 EGG16862.1 - 1.4e-39 136.2 48.8 1.9e-39 135.7 48.8 1.2 1 0 0 1 1 1 1 Amino acid permease RhoGAP PF00620.27 EGG16863.1 - 4.1e-48 163.1 0.0 9.2e-48 161.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EGG16863.1 - 1.7e-10 41.3 0.7 4.7e-10 39.9 0.2 2.1 2 0 0 2 2 1 1 PH domain SH3_2 PF07653.17 EGG16863.1 - 2.2e-07 30.5 0.0 4.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 EGG16863.1 - 2.3e-06 28.0 0.1 1.2e-05 25.7 0.1 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_1 PF00018.28 EGG16863.1 - 2.9e-06 26.8 0.1 6.4e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGG16863.1 - 4.9e-06 26.3 0.2 1.2e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain HAD_2 PF13419.6 EGG16863.1 - 0.0018 18.4 0.0 0.0018 18.4 0.0 2.4 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase PH_3 PF14593.6 EGG16863.1 - 0.0042 17.2 0.1 0.02 15.0 0.1 2.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGG16863.1 - 0.0047 17.2 0.1 0.016 15.5 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain TUG-UBL1 PF11470.8 EGG16863.1 - 0.033 14.4 1.1 0.17 12.1 0.0 2.7 3 0 0 3 3 3 0 TUG ubiquitin-like domain Sbi-IV PF11621.8 EGG16863.1 - 0.45 10.9 4.9 0.72 10.2 0.1 2.7 1 1 1 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI Peptidase_S46 PF10459.9 EGG16863.1 - 6 5.4 11.4 9.1 4.8 11.4 1.1 1 0 0 1 1 1 0 Peptidase S46 Occludin_ELL PF07303.13 EGG16863.1 - 6.8 7.5 11.9 0.5 11.1 1.5 3.5 2 1 1 3 3 3 0 Occludin homology domain ANAPC15 PF15243.6 EGG16864.1 - 1.3 9.5 9.0 0.41 11.1 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 ATP-synt_E PF05680.12 EGG16864.1 - 3.3 8.1 7.0 0.99 9.8 1.3 2.2 2 0 0 2 2 2 0 ATP synthase E chain Solute_trans_a PF03619.16 EGG16866.1 - 1.2e-99 333.2 13.9 1.5e-99 332.9 13.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha FtsX PF02687.21 EGG16866.1 - 1.1 9.8 7.3 8.5 6.9 0.8 3.5 3 0 0 3 3 3 0 FtsX-like permease family Secretin_N_2 PF07655.13 EGG16866.1 - 2.2 8.9 14.7 4 8.0 14.7 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Ephrin_rec_like PF07699.13 EGG16867.1 - 0.00074 19.2 1.1 0.0026 17.5 1.1 2.1 1 0 0 1 1 1 1 Putative ephrin-receptor like SPX PF03105.19 EGG16867.1 - 0.075 12.9 4.1 0.037 13.9 2.1 1.4 2 0 0 2 2 2 0 SPX domain Apt1 PF10351.9 EGG16867.1 - 0.32 9.8 7.5 0.48 9.2 7.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EGG16867.1 - 3.2 6.2 11.2 5.1 5.5 11.2 1.2 1 0 0 1 1 1 0 Macoilin family LRR_4 PF12799.7 EGG16868.1 - 2.7e-12 46.7 25.2 0.16 12.4 0.0 9.4 7 1 1 8 8 8 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGG16868.1 - 8.1e-08 31.7 28.6 0.063 13.4 0.0 12.0 15 0 0 15 15 15 2 Leucine Rich repeat MMR_HSR1 PF01926.23 EGG16868.1 - 0.00037 20.6 0.4 0.039 14.1 0.1 3.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EGG16868.1 - 0.00071 19.4 0.2 0.0025 17.6 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein LRR_1 PF00560.33 EGG16868.1 - 0.0011 19.2 18.9 2.9 8.8 0.1 10.1 9 2 0 9 9 9 1 Leucine Rich Repeat TRM13 PF05206.14 EGG16868.1 - 0.0015 18.1 3.5 0.0065 16.0 3.5 2.1 1 0 0 1 1 1 1 Methyltransferase TRM13 RsgA_GTPase PF03193.16 EGG16868.1 - 0.029 14.3 1.6 0.55 10.1 0.0 3.6 3 0 0 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 EGG16868.1 - 0.13 12.6 1.0 0.9 9.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain MIF4G_like PF09088.11 EGG16868.1 - 0.16 11.7 0.4 0.41 10.4 0.4 1.7 1 0 0 1 1 1 0 MIF4G like WD40 PF00400.32 EGG16870.1 - 9.7e-26 89.5 12.8 1.8e-08 34.9 0.0 6.1 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG16870.1 - 3.3e-07 30.5 0.8 0.3 11.4 0.0 5.1 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 EGG16870.1 - 0.087 12.4 3.3 6.1 6.3 0.0 3.3 3 1 1 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region Acetyltransf_CG PF14542.6 EGG16872.1 - 2.9e-19 69.0 0.0 3.9e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Ank_2 PF12796.7 EGG16873.1 - 7.4e-11 42.5 2.5 9.7e-06 26.1 0.3 4.2 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16873.1 - 1.6e-06 28.5 0.3 0.014 15.9 0.0 6.1 7 1 1 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16873.1 - 0.00013 22.1 0.2 6 7.8 0.0 6.7 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 EGG16873.1 - 0.00014 22.1 0.1 0.14 12.6 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) MutS_IV PF05190.18 EGG16873.1 - 0.64 10.4 3.1 1.3 9.4 0.2 2.9 3 0 0 3 3 3 0 MutS family domain IV CH PF00307.31 EGG16876.1 - 9.9e-25 86.8 14.3 2.1e-11 43.9 0.1 5.9 6 0 0 6 6 6 2 Calponin homology (CH) domain HAP1_N PF04849.13 EGG16876.1 - 0.0017 17.6 28.3 0.0017 17.6 28.3 8.8 3 2 3 7 7 7 2 HAP1 N-terminal conserved region BRE1 PF08647.11 EGG16876.1 - 0.002 18.2 8.2 0.002 18.2 8.2 14.5 5 3 8 14 14 14 3 BRE1 E3 ubiquitin ligase ERM PF00769.19 EGG16876.1 - 0.0039 17.0 29.3 0.0039 17.0 29.3 8.0 1 1 4 6 6 6 1 Ezrin/radixin/moesin family Mod_r PF07200.13 EGG16876.1 - 0.0045 17.1 14.5 0.0045 17.1 14.5 10.6 5 2 5 11 11 11 1 Modifier of rudimentary (Mod(r)) protein U3snoRNP10 PF12397.8 EGG16876.1 - 0.028 14.8 0.2 0.028 14.8 0.2 3.2 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 MCPsignal PF00015.21 EGG16876.1 - 0.1 12.4 34.4 0.036 13.9 7.9 5.1 2 2 2 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PikAIV_N PF18605.1 EGG16876.1 - 0.13 11.8 46.3 0.9 9.2 1.3 9.0 8 1 1 9 9 9 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain ECH_2 PF16113.5 EGG16877.1 - 6.4 6.2 10.5 0.58 9.6 4.6 2.1 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase Gallidermin PF02052.15 EGG16878.1 - 2.4 8.6 4.7 1.8 8.9 0.3 2.8 3 0 0 3 3 3 0 Gallidermin Trypsin_2 PF13365.6 EGG16880.1 - 3.9e-05 24.6 0.0 7.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGG16880.1 - 0.0008 19.3 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 2 Trypsin Peptidase_C3 PF00548.20 EGG16880.1 - 0.0097 15.8 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 1 3C cysteine protease (picornain 3C) FRQ PF09421.10 EGG16880.1 - 0.039 12.0 0.2 0.053 11.5 0.2 1.1 1 0 0 1 1 1 0 Frequency clock protein Nup54 PF13874.6 EGG16880.1 - 0.11 12.6 0.3 0.38 10.8 0.3 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 BST2 PF16716.5 EGG16880.1 - 1.2 9.7 4.5 0.83 10.3 0.3 2.6 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Patatin PF01734.22 EGG16881.1 - 1.6e-15 57.8 0.1 1.7e-14 54.5 0.1 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase Trypsin_2 PF13365.6 EGG16882.1 - 8.7e-10 39.7 0.0 8.3e-05 23.5 0.0 2.8 2 1 0 2 2 2 2 Trypsin-like peptidase domain Trypsin PF00089.26 EGG16882.1 - 2e-05 24.5 0.0 0.024 14.5 0.0 3.1 3 0 0 3 3 3 2 Trypsin Tae4 PF14113.6 EGG16882.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 Trypsin_2 PF13365.6 EGG16883.1 - 3.5e-08 34.5 0.0 6.3e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain Vmethyltransf_C PF08456.10 EGG16883.1 - 0.046 13.3 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral methyltransferase C-terminal DAAD PF18752.1 EGG16885.1 - 7e-91 305.1 3.7 7e-91 305.1 3.7 1.6 2 0 0 2 2 2 1 Dictyosteliid AID/APOBEC-like Deaminase Staygreen PF12638.7 EGG16885.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Staygreen protein Mad3_BUB1_I PF08311.12 EGG16886.1 - 1.2e-42 144.8 1.1 9.2e-42 141.9 1.7 2.3 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase_Tyr PF07714.17 EGG16886.1 - 0.0019 17.5 0.1 0.0019 17.5 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.11 EGG16886.1 - 0.0058 16.8 4.1 0.032 14.4 0.1 3.6 3 1 0 3 3 3 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 EGG16886.1 - 0.012 15.0 0.1 0.012 15.0 0.1 2.0 2 0 0 2 2 2 0 Protein kinase domain YqhR PF11085.8 EGG16887.1 - 0.12 12.3 1.0 0.17 11.8 1.0 1.3 1 0 0 1 1 1 0 Conserved membrane protein YqhR TPT PF03151.16 EGG16888.1 - 2.4e-11 43.5 10.8 2.4e-11 43.5 10.8 2.0 1 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 EGG16888.1 - 2e-07 31.3 27.0 5.2e-07 29.9 15.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EGG16888.1 - 0.00045 19.6 23.2 0.0025 17.1 23.2 2.0 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport SAM_PNT PF02198.16 EGG16891.1 - 0.0025 17.8 0.0 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain F-box PF00646.33 EGG16891.1 - 0.067 13.1 2.2 2.1 8.4 0.2 3.4 3 0 0 3 3 3 0 F-box domain H_lectin PF09458.10 EGG16892.1 - 6.9e-15 55.0 1.1 1.4e-14 54.0 1.1 1.6 1 0 0 1 1 1 1 H-type lectin domain F-box PF00646.33 EGG16893.1 - 0.18 11.7 1.3 0.68 9.9 0.2 2.6 3 0 0 3 3 3 0 F-box domain DUF3430 PF11912.8 EGG16894.1 - 1.5e-12 48.0 10.9 1.5e-12 48.0 10.9 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3430) SpoU_methylase PF00588.19 EGG16898.1 - 7.4e-27 94.3 0.3 1.9e-24 86.4 0.1 2.8 2 1 0 2 2 2 1 SpoU rRNA Methylase family RAI16-like PF10257.9 EGG16899.1 - 1.4e-81 274.1 0.0 4.3e-59 200.2 0.0 2.6 1 1 1 2 2 2 2 Retinoic acid induced 16-like protein Ank_2 PF12796.7 EGG16899.1 - 2.4e-25 88.9 26.8 0.00031 21.3 0.1 7.6 2 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16899.1 - 4.3e-15 55.9 11.1 0.71 10.5 0.0 9.6 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG16899.1 - 1.2e-09 38.2 4.1 23 5.4 0.0 10.2 7 2 5 12 12 12 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16899.1 - 8e-08 32.0 5.9 1.1e+02 3.9 0.0 11.9 15 0 0 15 15 15 0 Ankyrin repeat Ank PF00023.30 EGG16899.1 - 0.06 13.8 3.6 1.1e+02 3.6 0.1 6.1 5 1 0 5 5 5 0 Ankyrin repeat DUF4878 PF12870.7 EGG16899.1 - 0.13 12.6 0.2 24 5.3 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4878) TIG PF01833.24 EGG16900.1 - 2.4e-54 181.3 65.4 2.3e-12 46.8 0.3 11.9 12 1 1 13 13 13 7 IPT/TIG domain SdrD_B PF17210.3 EGG16900.1 - 9.4e-43 145.0 44.3 4e-07 30.3 0.1 12.0 12 0 0 12 12 12 8 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG16900.1 - 6.1e-21 74.5 53.6 0.00014 22.0 0.1 11.9 10 1 0 10 10 10 9 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 EGG16900.1 - 4.3e-05 23.6 3.5 0.18 11.9 0.0 5.5 7 1 0 8 8 8 2 Protein of unknown function (DUF2012) TIG PF01833.24 EGG16901.1 - 1.1e-30 105.5 47.2 4.1e-09 36.4 5.9 10.2 9 0 0 9 9 9 6 IPT/TIG domain DNase_II PF03265.15 EGG16901.1 - 1.5e-25 90.2 2.4 1.3e-14 54.2 0.3 3.6 3 0 0 3 3 3 2 Deoxyribonuclease II SdrD_B PF17210.3 EGG16901.1 - 1.8e-07 31.4 0.9 9.5e-05 22.6 0.0 4.3 4 0 0 4 4 4 1 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG16901.1 - 0.003 17.8 0.1 0.022 15.0 0.1 2.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Ank_2 PF12796.7 EGG16902.1 - 2e-12 47.5 5.8 7.6e-06 26.4 3.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG16902.1 - 1.3e-09 38.4 1.0 0.0043 17.6 0.3 4.7 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG16902.1 - 1.1e-06 28.4 1.1 1 10.2 0.0 5.5 6 1 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EGG16902.1 - 5.4e-06 26.6 1.6 0.72 10.2 0.1 4.2 3 2 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EGG16902.1 - 0.012 16.1 2.8 16 6.2 0.1 4.2 4 1 0 4 4 4 0 Ankyrin repeat DUF4878 PF12870.7 EGG16902.1 - 0.03 14.6 0.2 2 8.7 0.0 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4878) DUF1623 PF07785.11 EGG16902.1 - 0.095 12.9 0.9 2.6 8.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1623) PseudoU_synth_2 PF00849.22 EGG16903.1 - 6.8e-18 65.3 6.0 1.8e-11 44.4 0.2 3.3 3 0 0 3 3 3 2 RNA pseudouridylate synthase SR-25 PF10500.9 EGG16903.1 - 0.052 13.2 22.1 0.052 13.2 6.4 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Zip PF02535.22 EGG16903.1 - 0.69 9.1 7.9 0.37 9.9 2.7 2.3 3 0 0 3 3 3 0 ZIP Zinc transporter Folate_carrier PF01770.18 EGG16903.1 - 3.5 6.3 6.9 0.23 10.2 0.5 2.0 2 0 0 2 2 2 0 Reduced folate carrier Presenilin PF01080.17 EGG16903.1 - 4.7 5.9 10.7 2.1 7.0 4.3 2.3 2 0 0 2 2 2 0 Presenilin Pentapeptide PF00805.22 EGG16904.1 - 4.4e-20 71.0 27.0 2.8e-07 30.0 1.4 4.5 2 1 0 4 4 4 4 Pentapeptide repeats (8 copies) BTB_2 PF02214.22 EGG16904.1 - 8.2e-19 67.8 0.0 2.7e-18 66.1 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_4 PF13599.6 EGG16904.1 - 1.1e-18 67.1 34.4 1.4e-09 38.0 7.0 3.4 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EGG16904.1 - 1.8e-16 60.0 15.4 1.7e-06 28.1 1.3 4.3 2 1 2 4 4 4 4 Pentapeptide repeats (9 copies) CfAFP PF05264.11 EGG16904.1 - 0.00012 22.1 0.3 0.00012 22.1 0.3 2.7 2 1 1 3 3 3 1 Choristoneura fumiferana antifreeze protein (CfAFP) BTB PF00651.31 EGG16904.1 - 0.00019 21.6 0.0 0.00044 20.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 EGG16904.1 - 0.00019 21.5 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain UQ_con PF00179.26 EGG16905.1 - 1.7e-28 99.1 0.0 2.2e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glycos_transf_1 PF00534.20 EGG16905.1 - 0.18 11.3 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 SNF2_N PF00176.23 EGG16906.1 - 5.8e-66 222.6 0.6 1.7e-65 221.0 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG16906.1 - 0.026 14.9 0.1 0.32 11.4 0.0 2.9 3 0 0 3 3 3 0 Helicase conserved C-terminal domain HMA PF00403.26 EGG16907.1 - 0.79 10.2 3.0 1.5 9.3 0.0 2.0 2 0 0 2 2 2 0 Heavy-metal-associated domain EMC1_C PF07774.13 EGG16908.1 - 0.1 12.3 0.1 0.48 10.1 0.0 1.8 1 1 0 2 2 2 0 ER membrane protein complex subunit 1, C-terminal RNase_T PF00929.24 EGG16909.1 - 1.6e-20 74.3 0.0 4.4e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 EGG16909.1 - 8.5e-07 29.1 0.0 4.1e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 3' exoribonuclease, RNase T-like Glyoxalase PF00903.25 EGG16909.1 - 1.3e-05 25.4 0.0 0.00011 22.4 0.0 2.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EGG16909.1 - 0.076 12.9 1.2 9.9 6.1 0.1 3.1 3 0 0 3 3 3 0 Glyoxalase-like domain DUF3439 PF11921.8 EGG16909.1 - 4.5 7.3 11.9 0.096 12.6 1.3 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3439) LSM PF01423.22 EGG16910.1 - 2.7e-20 71.8 0.7 3.2e-20 71.6 0.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGG16910.1 - 3.1e-06 27.2 0.0 4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF150_C PF17384.2 EGG16910.1 - 0.079 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain FNIP PF05725.12 EGG16913.1 - 0.00023 21.3 0.4 0.022 14.9 0.0 3.9 4 0 0 4 4 4 1 FNIP Repeat DUF4834 PF16118.5 EGG16914.1 - 0.2 12.7 5.3 0.33 11.9 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) POX PF07526.11 EGG16914.1 - 0.23 12.0 1.0 0.37 11.4 1.0 1.4 1 0 0 1 1 1 0 Associated with HOX Menin PF05053.13 EGG16914.1 - 0.64 8.3 8.9 0.88 7.9 8.9 1.3 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 EGG16914.1 - 1.9 7.2 3.6 2.1 7.0 3.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4637 PF15470.6 EGG16914.1 - 2.4 7.9 4.4 3.7 7.2 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) HCO3_cotransp PF00955.21 EGG16914.1 - 4.3 6.0 5.7 6 5.6 5.7 1.1 1 0 0 1 1 1 0 HCO3- transporter family FH2 PF02181.23 EGG16915.1 - 2.2e-87 293.6 7.3 2.2e-87 293.6 7.3 3.4 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EGG16915.1 - 1.3e-36 125.9 5.2 1.3e-36 125.9 5.2 3.7 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGG16915.1 - 1.1e-32 113.2 0.3 1.1e-32 113.2 0.3 3.7 4 0 0 4 4 4 1 Diaphanous FH3 Domain C2 PF00168.30 EGG16915.1 - 6.9e-15 55.2 0.0 1.8e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain JAB PF01398.21 EGG16915.1 - 0.098 12.6 1.1 0.48 10.4 0.1 2.5 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Orbi_VP5 PF00901.17 EGG16915.1 - 3.8 5.8 9.9 0.18 10.1 2.7 2.2 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 Rcd1 PF04078.13 EGG16916.1 - 4.9e-110 366.9 0.6 6.2e-110 366.5 0.6 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like RICTOR_N PF14664.6 EGG16916.1 - 0.031 13.3 1.1 0.047 12.7 1.1 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term HA2 PF04408.23 EGG16917.1 - 1.8e-21 76.4 0.0 1.8e-21 76.4 0.0 1.9 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGG16917.1 - 1.3e-15 57.5 0.0 3.3e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGG16917.1 - 1.8e-06 28.3 0.0 4.3e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SRP54 PF00448.22 EGG16917.1 - 0.0038 16.9 0.1 0.0071 16.0 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ATPase PF06745.13 EGG16917.1 - 0.006 16.0 0.1 0.028 13.8 0.0 2.0 2 0 0 2 2 2 1 KaiC DEAD PF00270.29 EGG16917.1 - 0.0067 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EGG16917.1 - 0.01 16.2 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGG16917.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGG16917.1 - 0.019 14.0 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD-helicase PF00580.21 EGG16917.1 - 0.02 14.4 0.1 0.66 9.4 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 EGG16917.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGG16917.1 - 0.038 13.6 0.2 3.3 7.2 0.1 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EGG16917.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 EGG16917.1 - 0.069 13.7 0.4 0.31 11.6 0.2 2.0 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 EGG16917.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGG16917.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 EGG16917.1 - 0.24 11.9 0.2 0.24 11.9 0.2 2.3 2 1 1 3 3 3 0 AAA domain TIG PF01833.24 EGG16919.1 - 2.1e-11 43.7 4.5 5.4e-05 23.2 0.6 2.6 2 0 0 2 2 2 2 IPT/TIG domain EGF_2 PF07974.13 EGG16919.1 - 0.0044 17.3 6.4 0.014 15.8 6.4 1.9 1 0 0 1 1 1 1 EGF-like domain YmzC PF14157.6 EGG16919.1 - 0.038 14.1 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 YmzC-like protein EGF PF00008.27 EGG16919.1 - 0.86 10.0 10.0 0.32 11.3 6.6 2.2 2 0 0 2 2 2 0 EGF-like domain DDE_Tnp_1_7 PF13843.6 EGG16920.1 - 2.7e-31 109.1 0.9 4.4e-26 92.0 0.1 2.1 1 1 1 2 2 2 2 Transposase IS4 Phage_holin_5_2 PF16079.5 EGG16921.1 - 0.024 15.0 0.1 0.05 13.9 0.1 1.6 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V Erf4 PF10256.9 EGG16921.1 - 0.043 13.9 0.5 0.16 12.0 0.1 2.4 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF4131 PF13567.6 EGG16921.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) T6SS_HCP PF05638.12 EGG16924.1 - 3.8e-08 33.8 0.2 1.1e-06 29.1 0.0 2.6 2 1 0 2 2 2 1 Type VI secretion system effector, Hcp zf-C2H2 PF00096.26 EGG16925.1 - 1.1e-23 82.4 69.6 0.0028 18.0 0.4 9.6 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG16925.1 - 4e-20 71.2 67.3 7.9e-06 26.1 0.5 10.0 10 0 0 10 10 10 7 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGG16925.1 - 7.2e-17 60.6 71.1 0.02 15.7 0.3 9.8 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGG16925.1 - 0.01 16.1 5.2 0.041 14.2 1.0 7.8 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG16925.1 - 1.4 9.4 0.0 2.3 8.7 0.0 7.1 8 0 0 8 8 8 0 Zinc-finger of C2H2 type SDA1 PF05285.12 EGG16925.1 - 6.4 6.1 56.4 0.98 8.8 35.2 2.2 2 0 0 2 2 2 0 SDA1 Pkinase PF00069.25 EGG16926.1 - 4.4e-72 242.6 0.0 6.4e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16926.1 - 4.1e-36 124.6 0.0 5.3e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EGG16926.1 - 1.7e-21 76.7 0.2 3.4e-21 75.7 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGG16926.1 - 6.5e-07 29.7 0.8 7.1e-06 26.4 0.8 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EGG16926.1 - 3.5e-06 27.1 0.1 9.3e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGG16926.1 - 1.1e-05 25.6 1.0 4.5e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Kinase-like PF14531.6 EGG16926.1 - 0.0002 20.8 0.0 0.029 13.7 0.0 2.1 1 1 0 2 2 2 2 Kinase-like Pkinase_C PF00433.24 EGG16926.1 - 0.005 17.5 0.3 0.011 16.4 0.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_9 PF15410.6 EGG16926.1 - 0.021 15.2 0.3 0.089 13.2 0.0 2.1 2 1 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.6 EGG16926.1 - 0.045 14.1 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain APH PF01636.23 EGG16926.1 - 0.08 12.9 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG16926.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3791 PF12668.7 EGG16926.1 - 0.16 12.1 0.6 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) YpsA PF06908.11 EGG16927.1 - 0.00067 19.7 2.0 0.00067 19.7 2.0 2.7 2 1 0 2 2 2 1 YspA SLOG family tRNA-synt_2 PF00152.20 EGG16928.1 - 2.6e-89 299.4 0.2 3.2e-89 299.1 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGG16928.1 - 2.4e-08 33.9 0.0 5.5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGG16928.1 - 0.05 13.1 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) NST1 PF13945.6 EGG16929.1 - 8.9e-69 231.4 24.7 8.9e-69 231.4 24.7 8.7 5 3 2 7 7 7 2 Salt tolerance down-regulator SUIM_assoc PF16619.5 EGG16929.1 - 0.0085 16.1 3.0 0.0085 16.1 3.0 12.1 7 3 3 10 10 10 3 Unstructured region C-term to UIM in Ataxin3 GatB_N PF02934.15 EGG16930.1 - 1.5e-104 349.3 0.0 1.9e-104 348.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EGG16930.1 - 1.1e-35 122.6 0.0 3.8e-35 121.0 0.0 1.9 2 0 0 2 2 2 1 GatB domain Fe_hyd_lg_C PF02906.14 EGG16931.1 - 2.1e-77 260.1 0.0 3.5e-77 259.4 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 EGG16931.1 - 0.00082 19.4 0.1 0.0018 18.3 0.1 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit FAD_syn PF06574.12 EGG16931.1 - 0.0045 16.9 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 FAD synthetase Beta-lactamase PF00144.24 EGG16932.1 - 1.3e-39 136.3 0.0 2.4e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Peptidase_M15 PF01427.17 EGG16932.1 - 4e-31 108.3 0.0 7.1e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 D-ala-D-ala dipeptidase Peptidase_S11 PF00768.20 EGG16932.1 - 0.018 14.5 0.3 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 EGG16932.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase enzyme family Sec34 PF04136.15 EGG16933.1 - 1e-35 122.8 9.0 3.1e-35 121.3 7.6 2.2 2 0 0 2 2 2 1 Sec34-like family NOG1_N PF17835.1 EGG16933.1 - 0.00039 20.4 0.2 0.00084 19.3 0.2 1.5 1 0 0 1 1 1 1 NOG1 N-terminal helical domain SAM_PNT PF02198.16 EGG16937.1 - 5.5e-09 35.9 0.2 2.1e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 EGG16937.1 - 9.3e-06 25.8 1.2 0.075 13.3 0.1 2.7 2 0 0 2 2 2 2 Ste50p, sterile alpha motif SAM_2 PF07647.17 EGG16937.1 - 1.4e-05 25.1 0.1 0.047 13.8 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 EGG16937.1 - 0.0003 19.7 0.1 0.42 9.3 0.0 2.7 2 1 1 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 EGG16937.1 - 0.0071 15.7 0.3 0.071 12.5 0.3 2.2 1 1 0 1 1 1 1 Protein kinase domain SAM_1 PF00536.30 EGG16937.1 - 0.0098 16.3 0.4 0.075 13.5 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PCI PF01399.27 EGG16938.1 - 5.3e-23 81.5 1.4 4.2e-22 78.6 0.1 2.6 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EGG16938.1 - 1.3e-14 54.0 0.3 2.9e-14 52.9 0.3 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain TAXi_C PF14541.6 EGG16938.1 - 3.1e-11 43.3 0.0 7.6e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 EGG16938.1 - 5.3e-08 32.7 1.8 2.5e-07 30.4 1.8 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TSP_1 PF00090.19 EGG16938.1 - 0.056 13.7 27.1 0.017 15.3 3.8 3.8 3 1 1 4 4 4 0 Thrombospondin type 1 domain Aminotran_3 PF00202.21 EGG16939.1 - 4e-84 282.6 0.0 3.4e-68 230.2 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGG16939.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II TANGO2 PF05742.12 EGG16940.1 - 4.3e-48 164.6 1.2 1.9e-40 139.5 0.0 2.7 2 1 1 3 3 3 2 Transport and Golgi organisation 2 DnaJ PF00226.31 EGG16941.1 - 1.1e-19 70.3 2.9 2e-19 69.4 2.9 1.5 1 0 0 1 1 1 1 DnaJ domain RLL PF10036.9 EGG16941.1 - 0.0012 18.8 0.1 0.0014 18.6 0.1 1.1 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein TPR_1 PF00515.28 EGG16941.1 - 0.0027 17.5 0.4 0.011 15.5 0.4 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG16941.1 - 0.0032 17.5 0.1 0.014 15.5 0.1 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat PRC2_HTH_1 PF18118.1 EGG16941.1 - 0.054 14.3 2.9 0.087 13.6 2.9 1.4 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Mhr1 PF12829.7 EGG16941.1 - 0.14 12.2 0.7 4.5 7.4 0.1 2.3 1 1 1 2 2 2 0 Transcriptional regulation of mitochondrial recombination DUF5345 PF17280.2 EGG16941.1 - 0.22 11.5 0.1 0.55 10.3 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5345) GRP PF07172.11 EGG16941.1 - 0.7 10.6 13.1 1.4 9.6 13.1 1.6 1 0 0 1 1 1 0 Glycine rich protein family FXa_inhibition PF14670.6 EGG16943.1 - 3.6e-09 36.7 12.4 3.6e-09 36.7 12.4 3.2 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 EGG16943.1 - 4e-08 33.3 8.9 4e-08 33.3 8.9 3.8 4 0 0 4 4 4 1 Calcium-binding EGF domain EGF_3 PF12947.7 EGG16943.1 - 0.0047 17.1 6.5 0.0047 17.1 6.5 3.7 4 1 0 4 4 4 1 EGF domain cEGF PF12662.7 EGG16943.1 - 0.019 14.9 7.2 0.019 14.9 7.2 3.2 3 0 0 3 3 3 0 Complement Clr-like EGF-like Myc_N PF01056.18 EGG16944.1 - 0.031 14.2 5.0 0.041 13.8 5.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Macoilin PF09726.9 EGG16944.1 - 0.83 8.1 14.6 1 7.8 14.6 1.2 1 0 0 1 1 1 0 Macoilin family DUF4820 PF16091.5 EGG16944.1 - 7.3 5.9 11.5 4.5 6.6 9.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) C2 PF00168.30 EGG16945.1 - 5.5e-08 33.0 0.0 1.9e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 C2 domain DUF365 PF04033.12 EGG16945.1 - 1.2 9.4 0.0 1.2 9.4 0.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF365) VRR_NUC PF08774.11 EGG16946.1 - 2.7e-17 62.8 0.0 6.7e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Pex2_Pex12 PF04757.14 EGG16946.1 - 0.0038 16.9 0.2 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region Mitofilin PF09731.9 EGG16946.1 - 1.2 7.9 10.3 1.8 7.3 10.3 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Miga PF10265.9 EGG16946.1 - 4.3 6.2 10.8 7 5.5 10.8 1.3 1 0 0 1 1 1 0 Mitoguardin Pkinase_Tyr PF07714.17 EGG16947.1 - 1.1e-64 218.3 0.0 1.5e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG16947.1 - 4e-57 193.6 0.0 7.8e-57 192.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 EGG16947.1 - 4.9e-13 49.0 5.6 4.9e-13 49.0 5.6 2.4 2 0 0 2 2 2 1 IPT/TIG domain APH PF01636.23 EGG16947.1 - 0.028 14.3 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGG16947.1 - 0.19 10.4 0.0 0.19 10.4 0.0 1.9 3 0 0 3 3 3 0 Fungal protein kinase Thiolase_N PF00108.23 EGG16948.1 - 1.1e-66 224.8 0.1 2.4e-66 223.7 0.1 1.5 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGG16948.1 - 6.5e-44 148.5 0.0 1.4e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGG16948.1 - 0.0032 17.1 2.0 0.0054 16.3 1.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGG16948.1 - 0.087 12.7 2.0 1.6 8.7 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III YebO PF13974.6 EGG16949.1 - 0.73 10.0 2.9 1.9 8.6 2.9 1.7 1 0 0 1 1 1 0 YebO-like protein TIG PF01833.24 EGG16951.1 - 1.5e-07 31.4 20.8 0.0034 17.4 0.6 5.0 3 2 1 4 4 4 4 IPT/TIG domain Glyco_hydro_38N PF01074.22 EGG16955.1 - 4.7e-69 232.9 3.4 7.3e-69 232.3 3.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 EGG16955.1 - 4.5e-17 62.0 0.0 9.6e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 EGG16955.1 - 4.4e-14 53.1 1.7 7.9e-14 52.2 1.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain G3P_antiterm PF04309.12 EGG16955.1 - 0.12 11.8 0.1 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator PUB PF09409.10 EGG16956.1 - 0.053 13.5 0.1 0.074 13.0 0.1 1.2 1 0 0 1 1 1 0 PUB domain DUF2605 PF10792.9 EGG16956.1 - 0.22 11.5 0.0 0.24 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Aa_trans PF01490.18 EGG16957.1 - 4.4e-13 48.7 13.9 2e-12 46.6 12.6 1.8 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGG16957.1 - 0.0012 18.0 9.4 0.0021 17.2 9.4 1.4 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family SAE2 PF08573.10 EGG16959.1 - 7.1e-08 33.6 1.6 6.1e-06 27.3 0.1 6.0 2 2 2 4 4 4 2 DNA repair protein endonuclease SAE2/CtIP C-terminus bZIP_1 PF00170.21 EGG16960.1 - 3.8e-07 30.1 6.8 3.8e-07 30.1 6.8 3.7 4 0 0 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 EGG16960.1 - 1.6e-05 24.9 9.5 1.6e-05 24.9 9.5 4.2 4 1 0 4 4 4 1 Basic region leucine zipper Translin PF01997.16 EGG16962.1 - 9.1e-48 163.0 2.7 1.1e-47 162.7 2.7 1.1 1 0 0 1 1 1 1 Translin family Catalase-rel PF06628.12 EGG16962.1 - 0.036 14.3 0.4 0.57 10.4 0.0 2.5 1 1 1 2 2 2 0 Catalase-related immune-responsive BLOC1_2 PF10046.9 EGG16962.1 - 0.79 10.1 5.0 18 5.7 1.4 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CoA_transf_3 PF02515.17 EGG16963.1 - 1.2e-75 255.0 0.0 1.4e-75 254.7 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Acetyltransf_10 PF13673.7 EGG16964.1 - 3.2e-11 43.3 0.1 3.9e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG16964.1 - 1.6e-08 34.7 0.0 2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG16964.1 - 2.7e-05 24.5 0.0 3.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGG16964.1 - 0.0069 16.5 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG16964.1 - 0.0086 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Pkinase PF00069.25 EGG16965.1 - 7e-77 258.4 0.0 7e-77 258.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16965.1 - 1e-44 152.8 0.9 1.2e-44 152.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.19 EGG16965.1 - 8.8e-16 57.4 0.3 2.4e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 Kinase associated domain 1 Kinase-like PF14531.6 EGG16965.1 - 9e-07 28.5 0.0 4.1e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGG16965.1 - 0.001 18.1 0.3 0.001 18.1 0.3 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGG16965.1 - 0.0023 17.3 0.0 0.0049 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG16965.1 - 0.036 14.0 0.1 0.17 11.8 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Abhydrolase_1 PF00561.20 EGG16966.1 - 1.3e-21 77.4 0.0 9.2e-21 74.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG16966.1 - 6e-11 43.4 0.0 7.4e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG16966.1 - 7.2e-11 41.8 0.0 1.2e-10 41.1 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EGG16966.1 - 0.0016 18.1 0.2 0.34 10.5 0.0 2.5 1 1 1 2 2 2 2 Serine hydrolase (FSH1) Thioesterase PF00975.20 EGG16966.1 - 0.011 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 EGG16966.1 - 0.018 14.9 0.0 0.096 12.6 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ndr PF03096.14 EGG16966.1 - 0.038 12.7 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family Palm_thioest PF02089.15 EGG16966.1 - 0.047 13.5 0.0 0.086 12.7 0.0 1.4 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Esterase PF00756.20 EGG16966.1 - 0.072 12.7 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Putative esterase DLH PF01738.18 EGG16966.1 - 0.077 12.5 0.0 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family UPF0227 PF05728.12 EGG16966.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Glyco_hydro_31 PF01055.26 EGG16966.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 ALGX PF16822.5 EGG16966.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX Rap_GAP PF02145.15 EGG16967.1 - 1e-36 126.2 0.3 2.8e-36 124.8 0.3 1.8 1 0 0 1 1 1 1 Rap/ran-GAP LRR_6 PF13516.6 EGG16967.1 - 8.2e-13 47.3 22.9 2.5e-05 24.0 0.1 9.3 10 0 0 10 10 10 4 Leucine Rich repeat F-box-like PF12937.7 EGG16967.1 - 3.3e-05 23.7 0.1 7.8e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 EGG16967.1 - 2.5 9.0 12.0 41 5.3 0.0 7.2 6 1 0 6 6 6 0 Leucine Rich Repeat CSRNP_N PF16019.5 EGG16967.1 - 3.1 7.7 5.8 1.7 8.5 2.3 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus FNIP PF05725.12 EGG16968.1 - 6.5e-05 23.0 7.1 0.00079 19.5 0.4 7.1 6 1 2 8 8 8 4 FNIP Repeat Peptidase_C1 PF00112.23 EGG16969.1 - 4.7e-47 160.9 0.2 6.9e-47 160.3 0.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.26 EGG16969.1 - 4.3e-07 30.8 0.1 8.3e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Inhibitor_I29 PF08246.12 EGG16970.1 - 6.8e-13 48.8 0.0 1.7e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF2470 PF10615.9 EGG16970.1 - 0.14 12.8 0.0 0.42 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) DUF2326 PF10088.9 EGG16972.1 - 0.072 12.8 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) Orf78 PF06024.12 EGG16973.1 - 0.018 15.3 1.9 0.037 14.3 1.9 1.5 1 0 0 1 1 1 0 Orf78 (ac78) DUF4330 PF14221.6 EGG16973.1 - 0.023 14.9 0.3 0.032 14.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) DUF3755 PF12579.8 EGG16973.1 - 0.068 12.8 0.3 0.18 11.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) APC1_C PF18122.1 EGG16974.1 - 6.9e-27 94.4 0.8 2.1e-26 92.9 0.8 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 EGG16974.1 - 1e-12 48.8 8.9 2.1e-11 44.5 0.2 5.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EGG16974.1 - 7.1e-06 26.2 13.2 0.25 11.9 0.1 5.5 4 0 0 4 4 4 2 Proteasome/cyclosome repeat JUPITER PF17054.5 EGG16974.1 - 3e-05 23.7 1.3 3e-05 23.7 1.3 2.4 2 0 0 2 2 2 1 Microtubule-Associated protein Jupiter ABC2_membrane PF01061.24 EGG16975.1 - 1.4e-88 295.8 70.0 1.1e-47 162.2 29.8 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGG16975.1 - 8.2e-38 130.0 0.0 4.8e-19 69.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGG16975.1 - 3.8e-27 94.0 0.6 1.6e-24 85.6 0.0 3.8 4 0 0 4 4 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 EGG16975.1 - 7.3e-13 48.3 54.2 1.2e-07 31.2 16.5 3.5 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 EGG16975.1 - 3.2e-09 37.3 0.6 8.4e-09 35.9 0.6 1.7 1 1 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EGG16975.1 - 3.2e-08 33.7 0.1 3.4e-05 23.8 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EGG16975.1 - 8.7e-06 25.8 0.0 0.038 13.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGG16975.1 - 8.7e-06 25.4 0.3 0.0068 16.1 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG16975.1 - 7.3e-05 23.2 0.0 0.17 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGG16975.1 - 0.00033 20.9 0.2 0.56 10.5 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGG16975.1 - 0.0016 18.1 0.0 0.0063 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGG16975.1 - 0.0067 16.2 0.4 1.9 8.1 0.3 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGG16975.1 - 0.015 15.7 0.3 3.3 8.2 0.0 3.0 3 0 0 3 3 2 0 RNA helicase MMR_HSR1 PF01926.23 EGG16975.1 - 0.016 15.3 0.1 6.9 6.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 EGG16975.1 - 0.02 15.3 0.1 8.1 6.9 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGG16975.1 - 0.039 13.9 0.0 0.99 9.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 EGG16975.1 - 0.043 13.1 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 EGG16975.1 - 0.045 13.9 0.1 0.88 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGG16975.1 - 0.05 14.1 0.0 1.1 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGG16975.1 - 0.12 11.9 0.8 1.1 8.9 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.12 EGG16975.1 - 0.13 12.0 0.2 28 4.4 0.0 3.0 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EGG16975.1 - 0.17 11.8 0.5 4.1 7.3 0.3 2.3 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EGG16975.1 - 0.26 11.5 1.6 0.63 10.3 0.4 2.2 2 0 0 2 2 2 0 AAA domain Josephin PF02099.17 EGG16976.1 - 7e-17 62.0 6.3 5.1e-16 59.2 4.0 2.4 1 1 0 1 1 1 1 Josephin Sec20 PF03908.13 EGG16977.1 - 1.2e-18 66.8 3.5 1.2e-18 66.8 3.5 2.7 2 1 1 3 3 3 1 Sec20 Cytochrom_B562 PF07361.11 EGG16977.1 - 0.28 11.9 6.0 0.21 12.2 1.6 2.5 1 1 0 2 2 2 0 Cytochrome b562 SNARE PF05739.19 EGG16977.1 - 0.7 9.9 3.8 7.8 6.6 0.3 3.2 3 0 0 3 3 3 0 SNARE domain Ost4 PF10215.9 EGG16977.1 - 1.1 9.2 3.2 2.1 8.2 3.2 1.4 1 0 0 1 1 1 0 Oligosaccaryltransferase DUF2721 PF11026.8 EGG16977.1 - 1.9 8.4 4.3 0.61 10.0 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Zn_clus PF00172.18 EGG16979.1 - 4.1e-07 30.0 12.8 1.2e-06 28.5 12.8 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_3 PF08447.12 EGG16979.1 - 0.018 15.3 0.2 0.18 12.1 0.0 2.3 2 0 0 2 2 2 0 PAS fold PAS_9 PF13426.7 EGG16979.1 - 0.058 13.7 0.4 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 PAS domain Phage_pRha PF09669.10 EGG16979.1 - 1.4 9.6 3.6 8.8 7.0 3.6 2.5 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) Ribosomal_L28e PF01778.17 EGG16980.1 - 5.6e-34 117.3 2.7 6e-34 117.3 0.2 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EGG16980.1 - 3.5e-26 91.7 15.9 3.5e-26 91.7 15.9 2.7 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EGG16980.1 - 0.00038 19.9 20.4 0.00048 19.6 20.4 1.1 1 0 0 1 1 1 1 BUD22 zf-TRM13_CCCH PF11722.8 EGG16980.1 - 6.3 6.7 6.9 4.6 7.1 1.0 2.5 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein ribosomal_L24 PF17136.4 EGG16981.1 - 2.5e-14 53.4 0.1 4.7e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 EGG16981.1 - 1.8e-09 37.2 0.8 1.1e-07 31.5 0.7 2.3 2 0 0 2 2 2 2 KOW motif EF-hand_4 PF12763.7 EGG16982.1 - 8.2e-17 61.1 0.0 2.8e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EGG16982.1 - 0.02 14.4 0.1 0.067 12.8 0.1 2.0 1 0 0 1 1 1 0 EF hand TFIIA PF03153.13 EGG16982.1 - 0.3 11.1 48.1 1.4 8.8 36.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Malt_amylase_C PF16657.5 EGG16982.1 - 2 8.6 5.9 0.26 11.4 0.4 2.3 3 0 0 3 3 3 0 Maltogenic Amylase, C-terminal domain EAF PF09816.9 EGG16983.1 - 7e-12 45.6 0.3 7e-12 45.6 0.3 3.2 3 0 0 3 3 3 1 RNA polymerase II transcription elongation factor DNase_II PF03265.15 EGG16984.1 - 3.5e-07 29.8 0.5 0.05 12.9 0.0 3.0 2 1 0 2 2 2 2 Deoxyribonuclease II MACPF PF01823.19 EGG16985.1 - 6.4e-18 65.6 1.1 1.7e-17 64.3 1.1 1.7 1 0 0 1 1 1 1 MAC/Perforin domain PA14 PF07691.12 EGG16985.1 - 1.4e-07 31.4 0.0 3.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 PA14 domain MACPF PF01823.19 EGG16986.1 - 4.8e-23 82.4 1.4 1.3e-22 80.9 1.4 1.7 1 0 0 1 1 1 1 MAC/Perforin domain Pkinase PF00069.25 EGG16988.1 - 4e-31 108.3 5.1 1.6e-18 67.1 0.1 2.9 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG16988.1 - 9.3e-14 51.3 0.3 4.8e-12 45.7 0.1 2.8 3 0 0 3 3 3 1 Protein tyrosine kinase zf-RING_2 PF13639.6 EGG16988.1 - 9.4e-06 25.9 3.5 2.6e-05 24.5 3.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGG16988.1 - 1.6e-05 24.6 2.8 5.1e-05 23.0 2.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG16988.1 - 0.00033 20.6 4.2 0.0097 15.9 0.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Tmpp129 PF10272.9 EGG16988.1 - 0.00098 18.5 0.3 0.0024 17.3 0.3 1.6 1 0 0 1 1 1 1 Putative transmembrane protein precursor zf-C3HC4_3 PF13920.6 EGG16988.1 - 0.0046 16.8 3.0 0.016 15.0 3.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) APG6_N PF17675.1 EGG16988.1 - 0.042 14.4 11.6 0.082 13.4 11.6 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region zf-C3HC4_2 PF13923.6 EGG16988.1 - 0.097 12.5 9.3 0.033 14.0 4.3 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG16988.1 - 0.15 12.0 5.0 0.41 10.7 5.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain TMF_DNA_bd PF12329.8 EGG16988.1 - 0.2 11.7 15.4 0.078 13.0 1.2 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Nsp1_C PF05064.13 EGG16988.1 - 0.2 11.5 4.4 0.44 10.4 4.4 1.6 1 0 0 1 1 1 0 Nsp1-like C-terminal region zf-rbx1 PF12678.7 EGG16988.1 - 0.23 11.8 3.8 1.7 9.0 4.4 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger domain CCDC-167 PF15188.6 EGG16988.1 - 0.47 10.8 7.5 1 9.8 7.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Prefoldin_2 PF01920.20 EGG16988.1 - 0.48 10.4 11.9 2.7 8.0 0.6 2.4 2 0 0 2 2 2 0 Prefoldin subunit Rad50_zn_hook PF04423.14 EGG16988.1 - 0.49 10.3 0.0 0.49 10.3 0.0 3.8 4 0 0 4 4 4 0 Rad50 zinc hook motif IMD PF08397.11 EGG16988.1 - 0.68 9.3 8.0 1.5 8.2 8.0 1.5 1 0 0 1 1 1 0 IRSp53/MIM homology domain IBR PF01485.21 EGG16988.1 - 0.97 9.7 4.3 6.9 7.0 1.7 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DivIC PF04977.15 EGG16988.1 - 1.1 9.1 7.0 0.61 9.9 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator Wtap PF17098.5 EGG16988.1 - 1.1 9.2 12.6 0.29 11.0 2.2 2.3 1 1 1 2 2 2 0 WTAP/Mum2p family zf-RING_11 PF17123.5 EGG16988.1 - 1.1 9.0 7.3 2.7 7.8 5.0 2.7 2 1 0 2 2 2 0 RING-like zinc finger Tropomyosin_1 PF12718.7 EGG16988.1 - 5.6 7.1 16.8 0.21 11.8 4.0 2.2 1 1 1 2 2 2 0 Tropomyosin like Phage_GP20 PF06810.11 EGG16988.1 - 7.1 6.4 12.6 8.4 6.2 1.0 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 EF-hand_7 PF13499.6 EGG16989.1 - 1.9e-20 73.1 17.1 1.4e-13 51.1 1.1 4.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGG16989.1 - 1e-17 62.2 16.1 3.9e-05 22.9 0.0 5.0 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EGG16989.1 - 2.8e-14 51.7 7.8 0.00074 19.2 0.3 4.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EGG16989.1 - 1.4e-11 44.0 15.8 1.1e-08 34.7 0.6 4.8 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 EGG16989.1 - 1.7e-05 24.0 12.9 0.053 13.0 0.3 4.2 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 EGG16989.1 - 0.0067 16.4 0.2 0.0067 16.4 0.2 4.5 3 1 1 5 5 5 1 Cytoskeletal-regulatory complex EF hand TSC22 PF01166.18 EGG16989.1 - 0.048 14.0 0.3 0.048 14.0 0.3 12.3 10 4 5 15 15 15 0 TSC-22/dip/bun family EF-hand_9 PF14658.6 EGG16989.1 - 0.063 13.6 0.1 0.063 13.6 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain Auto_anti-p27 PF06677.12 EGG16990.1 - 1.1e-22 79.9 9.1 2.7e-13 49.8 1.4 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-piccolo PF05715.13 EGG16990.1 - 0.75 10.0 5.9 0.46 10.7 1.2 2.6 2 0 0 2 2 2 0 Piccolo Zn-finger DUF2387 PF09526.10 EGG16990.1 - 0.9 9.7 10.0 4.4 7.5 1.3 3.7 3 1 1 4 4 4 0 Probable metal-binding protein (DUF2387) TFIIF_alpha PF05793.12 EGG16990.1 - 1.3 7.6 16.4 0.011 14.3 4.7 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TauE PF01925.19 EGG16991.1 - 7.5e-27 94.5 24.2 4.7e-14 52.6 13.4 2.5 2 1 1 3 3 3 2 Sulfite exporter TauE/SafE DAG1 PF05454.11 EGG16991.1 - 0.00049 19.6 2.0 1.1 8.6 0.0 3.2 3 0 0 3 3 3 2 Dystroglycan (Dystrophin-associated glycoprotein 1) EVI2A PF05399.11 EGG16991.1 - 0.16 11.6 10.1 2.1 7.9 0.3 3.3 3 0 0 3 3 3 0 Ectropic viral integration site 2A protein (EVI2A) Saf_2TM PF18303.1 EGG16991.1 - 1 8.9 6.7 28 4.3 0.0 4.4 3 1 1 4 4 4 0 SAVED-fused 2TM effector domain Ion_trans PF00520.31 EGG16991.1 - 1.4 8.1 10.4 4.1 6.6 6.6 3.0 3 1 0 3 3 3 0 Ion transport protein UPF0561 PF10573.9 EGG16993.1 - 0.059 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 SERTA PF06031.13 EGG16993.1 - 0.075 12.7 0.1 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 SERTA motif Zap1_zf2 PF18217.1 EGG16994.1 - 0.11 12.5 4.0 0.47 10.5 0.1 3.1 3 0 0 3 3 3 0 Zap1 zinc finger 2 zf-Di19 PF05605.12 EGG16994.1 - 0.4 11.0 2.9 6.7 7.1 0.2 3.6 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 EGG16994.1 - 4 7.8 7.1 1.7 9.0 0.5 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF3336 PF11815.8 EGG16995.1 - 7.1e-34 116.5 1.2 1e-33 115.9 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Catalase PF00199.19 EGG16996.1 - 6e-179 595.1 5.6 2.2e-125 418.8 0.8 2.1 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.12 EGG16996.1 - 2.5e-23 82.0 0.0 6.1e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF3050 PF11251.8 EGG16998.1 - 0.0041 16.8 0.5 0.0055 16.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) SR-25 PF10500.9 EGG16998.1 - 0.41 10.2 7.8 0.57 9.8 7.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein E2F_TDP PF02319.20 EGG16999.1 - 2e-28 98.2 0.0 2.4e-13 49.9 0.0 2.8 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain YL1 PF05764.13 EGG16999.1 - 0.0092 16.1 20.4 0.0092 16.1 20.4 2.5 2 0 0 2 2 2 1 YL1 nuclear protein Imm5 PF14423.6 EGG16999.1 - 5.1 7.3 6.4 19 5.4 6.4 2.0 1 0 0 1 1 1 0 Immunity protein Imm5 DUF4637 PF15470.6 EGG16999.1 - 6.3 6.5 16.6 0.92 9.2 7.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) MFS_1 PF07690.16 EGG17000.1 - 7.8e-40 136.9 36.3 4.9e-21 75.1 16.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG17000.1 - 4.5e-14 52.2 28.8 1.2e-08 34.3 9.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter ComGF PF15980.5 EGG17000.1 - 0.0064 16.8 1.9 0.013 15.8 1.9 1.4 1 0 0 1 1 1 1 Putative Competence protein ComGF MFS_2 PF13347.6 EGG17000.1 - 0.058 12.0 25.5 0.051 12.1 4.2 3.4 2 1 0 2 2 2 0 MFS/sugar transport protein TMEM141 PF15110.6 EGG17000.1 - 0.12 13.0 0.3 0.31 11.6 0.3 1.7 1 0 0 1 1 1 0 TMEM141 protein family CelTOS PF18659.1 EGG17001.1 - 0.01 16.3 0.1 0.018 15.5 0.1 1.5 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites DUF5609 PF18429.1 EGG17001.1 - 0.087 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5609) Rrn6 PF10214.9 EGG17002.1 - 0.12 10.8 8.7 0.14 10.6 8.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PP2C PF00481.21 EGG17003.1 - 3e-06 27.1 0.0 0.017 14.7 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EGG17003.1 - 0.074 13.0 0.0 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) CYTH PF01928.21 EGG17004.1 - 3.2e-09 37.0 0.0 6.4e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 CYTH domain SR-25 PF10500.9 EGG17004.1 - 0.058 13.0 1.2 0.12 12.0 1.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IR1-M PF12185.8 EGG17004.1 - 0.084 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain DUF5470 PF17564.2 EGG17004.1 - 0.17 12.1 2.8 0.51 10.6 2.8 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5470) SnoaL_2 PF12680.7 EGG17005.1 - 0.0011 19.6 0.0 0.0012 19.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EGG17005.1 - 0.024 15.0 0.0 0.026 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) MpPF1 PF07668.11 EGG17005.1 - 0.04 13.2 0.5 0.047 13.0 0.5 1.1 1 0 0 1 1 1 0 M penetrans paralogue family 1 Par3_HAL_N_term PF12053.8 EGG17007.1 - 0.0013 18.9 0.1 0.019 15.2 0.0 2.6 3 0 0 3 3 3 1 N-terminal of Par3 and HAL proteins AAA_22 PF13401.6 EGG17008.1 - 1.2e-11 45.0 0.0 3.4e-11 43.6 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 EGG17008.1 - 1.6e-11 44.7 0.1 3.9e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 EGG17008.1 - 1.3e-07 31.5 0.0 6e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain DUF2075 PF09848.9 EGG17008.1 - 9.9e-06 25.0 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 EGG17008.1 - 2.8e-05 23.7 0.6 0.00015 21.3 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 EGG17008.1 - 0.00091 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGG17008.1 - 0.0029 18.0 0.1 0.037 14.4 0.0 2.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 EGG17008.1 - 0.013 15.8 0.2 0.15 12.4 0.2 2.2 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 EGG17008.1 - 0.019 14.2 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase ATPase PF06745.13 EGG17008.1 - 0.023 14.1 0.3 0.18 11.1 0.1 2.5 3 0 0 3 3 3 0 KaiC AAA_lid_10 PF17872.1 EGG17008.1 - 0.032 14.3 0.2 0.38 10.9 0.1 2.3 1 1 1 2 2 2 0 AAA lid domain AAA_32 PF13654.6 EGG17008.1 - 0.047 12.5 0.5 2.1 7.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 EGG17008.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_11 PF13086.6 EGG17008.1 - 0.29 10.9 2.3 0.53 10.0 1.5 2.0 2 1 0 2 2 2 0 AAA domain RT_RNaseH PF17917.1 EGG17009.1 - 3.1e-30 104.6 0.0 8e-30 103.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EGG17009.1 - 1.9e-28 98.4 0.0 4.3e-28 97.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EGG17009.1 - 2.2e-08 33.9 0.0 4.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5020 PF16412.5 EGG17009.1 - 0.0053 16.6 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5020) OMPdecase PF00215.24 EGG17010.1 - 1.4e-75 253.8 0.6 2e-75 253.3 0.6 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 EGG17010.1 - 3.6e-10 39.6 0.3 7.3e-10 38.6 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGG17010.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase TMEM232 PF15877.5 EGG17010.1 - 0.058 12.4 0.1 0.084 11.9 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 232 PRTase_2 PF15609.6 EGG17010.1 - 0.12 11.8 0.1 0.32 10.5 0.1 1.7 1 1 0 1 1 1 0 Phosphoribosyl transferase CD225 PF04505.12 EGG17011.1 - 0.15 12.2 1.2 0.24 11.6 1.2 1.3 1 0 0 1 1 1 0 Interferon-induced transmembrane protein COMM_domain PF07258.14 EGG17012.1 - 6.2e-21 74.3 0.5 1.2e-20 73.4 0.1 1.7 2 0 0 2 2 2 1 COMM domain Sid-5 PF17204.3 EGG17015.1 - 9.4e-05 22.5 6.6 0.0017 18.5 0.5 2.0 2 0 0 2 2 2 2 Sid-5 family DUF2207 PF09972.9 EGG17015.1 - 0.096 11.4 1.2 0.1 11.3 1.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 EGG17015.1 - 0.099 13.5 4.0 0.34 11.8 1.3 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Wzy_C PF04932.15 EGG17015.1 - 0.17 11.5 2.2 0.2 11.3 2.2 1.1 1 0 0 1 1 1 0 O-Antigen ligase Sprouty PF05210.13 EGG17015.1 - 0.2 12.0 0.0 0.21 12.0 0.0 1.1 1 0 0 1 1 1 0 Sprouty protein (Spry) ODV-E18 PF10717.9 EGG17015.1 - 0.44 10.4 7.2 2.2 8.2 0.7 2.2 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 KASH PF10541.9 EGG17015.1 - 0.72 10.2 3.3 21 5.5 0.0 2.1 1 1 1 2 2 2 0 Nuclear envelope localisation domain RCR PF12273.8 EGG17015.1 - 5.3 7.7 4.8 4.4 8.0 1.3 2.0 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Baculo_11_kDa PF06143.11 EGG17015.1 - 6.8 6.3 11.2 2.2 7.9 1.7 2.1 1 1 1 2 2 2 0 Baculovirus 11 kDa family DUF3671 PF12420.8 EGG17015.1 - 8 6.6 9.7 1.4 9.0 2.4 1.7 1 1 1 2 2 2 0 Protein of unknown function FNIP PF05725.12 EGG17016.1 - 2.9 8.2 7.0 22 5.3 0.5 3.4 2 1 0 3 3 3 0 FNIP Repeat Siah-Interact_N PF09032.11 EGG17017.1 - 0.027 14.8 1.1 0.027 14.8 1.1 1.8 1 1 1 2 2 2 0 Siah interacting protein, N terminal AAA_16 PF13191.6 EGG17018.1 - 0.15 12.5 0.0 12 6.2 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain FTH PF01827.27 EGG17019.1 - 0.018 14.8 0.5 0.065 13.0 0.5 1.9 1 0 0 1 1 1 0 FTH domain UCH PF00443.29 EGG17019.1 - 0.022 14.2 0.0 0.04 13.4 0.0 1.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF1829 PF08862.10 EGG17019.1 - 1.3 9.6 5.4 10 6.7 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF1829 MFS_1 PF07690.16 EGG17024.1 - 5e-15 55.3 34.6 3.8e-05 22.8 0.5 4.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG17024.1 - 0.00021 20.3 0.0 0.00021 20.3 0.0 3.9 3 1 0 3 3 3 1 Sugar (and other) transporter UCH PF00443.29 EGG17025.1 - 8.9e-50 169.6 1.3 8.9e-50 169.6 1.3 4.1 2 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase SnoaL_2 PF12680.7 EGG17026.1 - 0.0016 19.0 0.0 0.0018 18.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EGG17026.1 - 0.026 14.9 0.0 0.029 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Methyltransf_2 PF00891.18 EGG17027.1 - 6.5e-35 120.3 0.0 8.6e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain HTH_11 PF08279.12 EGG17027.1 - 0.00053 19.9 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 EGG17027.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 EGG17027.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator MarR PF01047.22 EGG17027.1 - 0.016 15.1 0.1 0.038 13.9 0.1 1.7 1 0 0 1 1 1 0 MarR family IF2_N PF04760.15 EGG17027.1 - 0.017 15.0 0.0 0.047 13.5 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Dimerisation2 PF16864.5 EGG17027.1 - 0.033 14.2 0.1 0.074 13.0 0.1 1.6 1 0 0 1 1 1 0 Dimerisation domain HTH_24 PF13412.6 EGG17027.1 - 0.04 13.5 0.0 0.2 11.3 0.0 2.3 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 EGG17027.1 - 0.053 13.6 0.3 0.092 12.8 0.3 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_43 PF09904.9 EGG17027.1 - 0.14 12.1 0.2 0.92 9.5 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_27 PF13463.6 EGG17027.1 - 0.17 12.4 0.1 0.39 11.3 0.1 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_15 PF12324.8 EGG17027.1 - 0.17 11.8 0.0 0.9 9.5 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase SnoaL_2 PF12680.7 EGG17028.1 - 0.0011 19.6 0.0 0.0012 19.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EGG17028.1 - 0.024 15.0 0.0 0.026 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) MpPF1 PF07668.11 EGG17028.1 - 0.04 13.2 0.5 0.047 13.0 0.5 1.1 1 0 0 1 1 1 0 M penetrans paralogue family 1 PRELI PF04707.14 EGG17029.1 - 4.6e-28 98.0 0.0 5.6e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family DUF1732 PF08340.11 EGG17030.1 - 0.035 14.1 0.1 0.068 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) DUF1387 PF07139.11 EGG17030.1 - 0.1 12.3 3.7 0.14 11.9 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SeqA PF03925.13 EGG17030.1 - 0.16 12.0 0.9 0.78 9.7 0.2 2.0 2 0 0 2 2 2 0 SeqA protein C-terminal domain ATG27 PF09451.10 EGG17030.1 - 0.56 10.0 2.5 0.47 10.3 0.3 2.0 2 1 0 2 2 2 0 Autophagy-related protein 27 UFC1 PF08694.11 EGG17031.1 - 1.2e-82 275.1 0.3 1.3e-82 274.9 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 EGG17031.1 - 0.032 13.9 0.3 0.049 13.3 0.3 1.5 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme RWD PF05773.22 EGG17031.1 - 0.12 12.6 0.3 0.2 11.9 0.3 1.4 1 1 0 1 1 1 0 RWD domain GTP_EFTU PF00009.27 EGG17032.1 - 2.1e-56 190.6 0.1 2.1e-56 190.6 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGG17032.1 - 2.8e-13 49.7 0.0 8.4e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGG17032.1 - 3.1e-10 40.3 0.0 8e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGG17032.1 - 4.7e-10 39.4 0.3 3e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.18 EGG17032.1 - 0.0001 22.1 0.0 0.0006 19.6 0.0 2.4 1 1 1 2 2 2 1 Elongation factor G, domain IV Ureide_permease PF07168.11 EGG17032.1 - 0.099 11.4 0.2 0.19 10.4 0.2 1.4 1 0 0 1 1 1 0 Ureide permease Mito_carr PF00153.27 EGG17033.1 - 3.6e-61 203.1 2.4 6.2e-20 70.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Yae1_N PF09811.9 EGG17035.1 - 5.3e-09 35.6 3.0 8.6e-09 35.0 3.0 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Chibby PF14645.6 EGG17036.1 - 4.6e-07 30.3 4.5 5.4e-07 30.0 4.5 1.2 1 0 0 1 1 1 1 Chibby family JAKMIP_CC3 PF16034.5 EGG17036.1 - 0.015 15.2 2.3 0.023 14.7 2.3 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain DUF3847 PF12958.7 EGG17036.1 - 0.043 13.9 0.7 0.068 13.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) DUF1192 PF06698.11 EGG17036.1 - 0.085 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DEAD PF00270.29 EGG17037.1 - 6.3e-49 166.1 0.0 1.1e-48 165.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG17037.1 - 1.3e-29 102.7 0.0 1.7e-28 99.2 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PRIMA1 PF16101.5 EGG17037.1 - 0.19 11.8 1.5 0.45 10.6 1.5 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TraF PF13728.6 EGG17037.1 - 4.7 7.0 11.7 0.17 11.7 3.5 2.4 2 0 0 2 2 2 0 F plasmid transfer operon protein Mito_fiss_reg PF05308.11 EGG17037.1 - 6 6.9 12.8 0.46 10.5 5.0 2.6 2 0 0 2 2 2 0 Mitochondrial fission regulator DnaJ_C PF01556.18 EGG17038.1 - 3.9e-40 137.3 0.1 7.7e-40 136.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGG17038.1 - 3e-25 88.1 2.5 6.7e-25 87.0 2.5 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGG17038.1 - 2e-11 44.1 21.8 2e-11 44.1 21.8 2.4 2 0 0 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 EGG17038.1 - 0.1 12.5 19.9 0.88 9.6 3.4 3.5 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF4834 PF16118.5 EGG17038.1 - 8.8 7.4 6.6 33 5.5 6.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Lectin_C PF00059.21 EGG17039.1 - 0.066 13.9 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Lectin C-type domain TIG PF01833.24 EGG17040.1 - 1.2e-10 41.3 3.0 1.5e-10 41.0 3.0 1.1 1 0 0 1 1 1 1 IPT/TIG domain DUF4533 PF15047.6 EGG17040.1 - 0.035 13.7 0.1 0.043 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) TIG PF01833.24 EGG17041.1 - 0.00032 20.7 2.7 0.0041 17.2 0.1 2.9 2 0 0 2 2 2 1 IPT/TIG domain TcfC PF16967.5 EGG17041.1 - 0.045 13.2 0.0 0.18 11.3 0.0 2.0 1 0 0 1 1 1 0 E-set like domain hEGF PF12661.7 EGG17041.1 - 0.13 12.9 4.0 0.34 11.6 4.0 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.13 EGG17041.1 - 0.28 11.6 5.5 0.7 10.3 5.5 1.6 1 0 0 1 1 1 0 EGF-like domain Pkinase_Tyr PF07714.17 EGG17042.1 - 1.2e-56 191.9 0.0 1.9e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG17042.1 - 4.6e-56 190.1 0.1 9.9e-56 189.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain RasGEF PF00617.19 EGG17042.1 - 6.9e-24 85.0 0.1 2.4e-23 83.2 0.0 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGG17042.1 - 3.6e-17 62.5 0.7 3.6e-17 62.5 0.7 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif Haspin_kinase PF12330.8 EGG17042.1 - 5.2e-06 25.6 0.1 5.2e-06 25.6 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGG17042.1 - 0.0047 15.7 2.4 0.0056 15.5 0.1 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGG17042.1 - 0.0076 15.6 1.9 0.013 14.9 0.2 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGG17042.1 - 0.0086 15.7 0.0 0.027 14.0 0.0 1.8 1 0 0 1 1 1 1 Choline/ethanolamine kinase NAD_Gly3P_dh_N PF01210.23 EGG17042.1 - 0.031 14.3 0.0 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus APH PF01636.23 EGG17042.1 - 0.037 14.0 0.0 0.096 12.6 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 EGG17043.1 - 7.7e-49 163.7 18.5 2e-17 63.1 1.0 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG17043.1 - 5e-37 126.0 19.2 4.1e-18 65.4 2.6 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 EGG17043.1 - 0.00011 22.2 0.4 1.4 9.1 0.1 3.4 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EGG17043.1 - 0.00015 21.8 0.8 1 9.4 0.1 3.8 1 1 2 3 3 3 2 SLIDE COPI_C PF06957.11 EGG17043.1 - 0.02 13.6 0.1 0.02 13.6 0.1 2.3 2 1 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus SANT_DAMP1_like PF16282.5 EGG17043.1 - 0.072 13.3 1.2 0.8 9.9 0.1 2.9 2 1 2 4 4 4 0 SANT/Myb-like domain of DAMP1 DUF5591 PF17884.1 EGG17043.1 - 0.1 12.5 0.5 1.5 8.7 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5591) Atg29_N PF18388.1 EGG17043.1 - 0.3 10.9 2.3 1.6 8.6 0.3 2.6 2 0 0 2 2 2 0 Atg29 N-terminal domain Dynein_light PF01221.18 EGG17043.1 - 9.4 6.6 6.9 6.6 7.1 0.1 3.2 2 1 0 3 3 3 0 Dynein light chain type 1 SUIM_assoc PF16619.5 EGG17044.1 - 0.2 11.7 6.1 0.32 11.1 6.1 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF3955 PF13127.6 EGG17044.1 - 0.66 9.8 3.1 0.93 9.4 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3955) DUF1702 PF08012.11 EGG17047.1 - 0.027 13.4 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) Xpo1 PF08389.12 EGG17050.1 - 0.017 15.2 1.3 0.088 12.9 1.2 2.2 2 0 0 2 2 2 0 Exportin 1-like protein V-ATPase_H_C PF11698.8 EGG17050.1 - 0.16 12.1 1.2 0.41 10.8 0.4 2.1 1 1 1 2 2 2 0 V-ATPase subunit H DUF5621 PF18532.1 EGG17051.1 - 0.017 15.0 0.2 0.078 12.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5621) ThrE_2 PF12821.7 EGG17054.1 - 0.065 13.4 1.5 0.2 11.8 1.5 1.8 1 1 0 1 1 1 0 Threonine/Serine exporter, ThrE FTO_CTD PF12934.7 EGG17054.1 - 0.083 12.6 0.3 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 FTO C-terminal domain VPS11_C PF12451.8 EGG17055.1 - 0.84 9.9 2.7 11 6.4 0.1 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal FTO_CTD PF12934.7 EGG17056.1 - 0.016 15.0 2.5 2.1 8.1 0.0 3.4 3 0 0 3 3 3 0 FTO C-terminal domain PspB PF06667.12 EGG17058.1 - 0.18 11.8 0.7 0.43 10.7 0.1 2.0 2 0 0 2 2 2 0 Phage shock protein B DDE_Tnp_1_7 PF13843.6 EGG17059.1 - 1.4e-19 70.7 11.2 1.8e-11 44.0 0.1 4.4 2 2 2 4 4 4 3 Transposase IS4 MAP65_ASE1 PF03999.12 EGG17059.1 - 0.15 10.8 13.6 0.16 10.6 13.6 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SOG2 PF10428.9 EGG17059.1 - 0.22 10.7 26.3 0.31 10.2 26.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CCDC84 PF14968.6 EGG17059.1 - 5.9 6.4 9.2 9.3 5.8 9.2 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 DUF966 PF06136.13 EGG17059.1 - 8.2 6.0 13.1 12 5.5 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SWI-SNF_Ssr4 PF08549.10 EGG17059.1 - 9.8 4.7 15.0 16 4.0 15.0 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SMYLE_N PF18615.1 EGG17059.1 - 9.9 5.6 10.5 14 5.1 10.5 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF4598 PF15370.6 EGG17062.1 - 1.4e-15 57.7 3.7 1.4e-15 57.7 3.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) PLDc_2 PF13091.6 EGG17064.1 - 1.8e-16 60.3 0.0 6.1e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGG17064.1 - 1.5e-07 31.3 0.8 0.02 15.0 0.5 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif SET PF00856.28 EGG17065.1 - 1.6e-14 54.6 0.1 4.3e-14 53.2 0.1 1.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGG17065.1 - 6.6e-07 29.3 7.8 6.6e-07 29.3 7.8 1.9 2 0 0 2 2 2 1 MYND finger AAA PF00004.29 EGG17066.1 - 7.4e-64 214.1 0.1 2.5e-35 121.8 0.0 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG17066.1 - 1.4e-09 38.6 0.0 0.0075 16.7 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EGG17066.1 - 7.2e-08 32.5 0.3 0.0066 16.4 0.0 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGG17066.1 - 1.2e-06 28.8 1.0 0.018 15.3 0.1 4.1 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EGG17066.1 - 5.5e-05 23.4 0.0 0.21 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EGG17066.1 - 6.5e-05 22.9 0.1 0.18 11.8 0.0 3.3 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EGG17066.1 - 0.00021 21.1 0.0 0.043 13.6 0.0 3.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EGG17066.1 - 0.00037 21.0 0.0 0.2 12.2 0.0 3.3 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 EGG17066.1 - 0.00049 20.5 4.1 0.52 10.7 0.0 4.2 4 0 0 4 4 3 2 RNA helicase AAA_3 PF07726.11 EGG17066.1 - 0.00072 19.4 0.0 2.5 8.0 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGG17066.1 - 0.00097 19.7 1.0 0.18 12.3 0.0 4.0 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EGG17066.1 - 0.0017 18.3 0.4 3.9 7.3 0.0 3.5 4 0 0 4 4 4 2 NACHT domain AAA_7 PF12775.7 EGG17066.1 - 0.0043 16.6 0.0 1.6 8.2 0.0 2.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 EGG17066.1 - 0.0044 17.3 0.0 1.1 9.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGG17066.1 - 0.011 15.5 0.0 1.8 8.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGG17066.1 - 0.011 15.0 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 EGG17066.1 - 0.034 14.4 0.0 0.72 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGG17066.1 - 0.034 14.1 0.8 3.7 7.4 0.0 2.8 3 0 0 3 3 2 0 NTPase AAA_30 PF13604.6 EGG17066.1 - 0.036 13.8 0.0 9.8 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EGG17066.1 - 0.056 13.2 0.0 6.4 6.4 0.0 2.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 EGG17066.1 - 0.057 12.8 0.4 9.9 5.5 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EGG17066.1 - 0.063 13.0 0.0 17 5.2 0.0 3.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EGG17066.1 - 0.14 11.9 0.0 19 5.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 EGG17066.1 - 0.16 11.8 15.2 0.96 9.2 0.0 4.4 4 1 0 4 4 3 0 AAA domain Ncstrn_small PF18266.1 EGG17067.1 - 2.8e-37 128.3 0.5 1.8e-36 125.7 0.0 2.5 3 0 0 3 3 3 1 Nicastrin small lobe Nicastrin PF05450.15 EGG17067.1 - 7e-35 120.6 3.8 1.1e-34 119.9 3.8 1.3 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 EGG17067.1 - 0.00034 20.3 0.4 0.00096 18.9 0.4 1.7 1 1 0 1 1 1 1 Peptidase family M28 HSP33 PF01430.19 EGG17068.1 - 1.2e-49 169.1 0.0 1.8e-49 168.5 0.0 1.3 1 1 0 1 1 1 1 Hsp33 protein ANAPC4_WD40 PF12894.7 EGG17069.1 - 7.6e-24 83.8 1.2 0.00012 22.3 0.2 6.8 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG17069.1 - 5.7e-22 77.6 7.6 1.6e-07 31.9 0.3 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat PD40 PF07676.12 EGG17069.1 - 0.0002 21.2 1.9 0.12 12.4 0.1 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat TFIIA PF03153.13 EGG17069.1 - 0.0008 19.5 11.1 0.001 19.1 11.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PSII_BNR PF14870.6 EGG17069.1 - 0.002 17.4 0.0 0.0042 16.4 0.0 1.5 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 WD40_like PF17005.5 EGG17069.1 - 0.0022 17.4 0.1 0.15 11.4 0.0 3.0 2 1 1 3 3 3 1 WD40-like domain Peptidase_S9_N PF02897.15 EGG17069.1 - 0.013 14.3 0.0 0.013 14.3 0.0 3.2 4 0 0 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain CDK2AP PF09806.9 EGG17069.1 - 0.043 13.9 9.8 0.22 11.6 10.6 1.7 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.9 EGG17069.1 - 0.091 12.4 15.8 0.18 11.4 15.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S30 PF01577.16 EGG17069.1 - 0.093 12.3 1.5 0.86 9.2 2.3 1.9 2 0 0 2 2 2 0 Potyvirus P1 protease Spt20 PF12090.8 EGG17069.1 - 0.15 11.7 22.8 0.28 10.8 22.8 1.4 1 0 0 1 1 1 0 Spt20 family MPM1 PF17234.2 EGG17069.1 - 0.21 11.8 8.4 0.41 10.9 8.4 1.5 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 GREB1 PF15782.5 EGG17069.1 - 0.44 7.6 13.1 0.61 7.1 13.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 EGG17069.1 - 0.54 8.9 10.0 0.68 8.6 10.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.15 EGG17069.1 - 0.78 9.2 12.7 1.4 8.4 12.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SOG2 PF10428.9 EGG17069.1 - 0.79 8.9 15.0 1.1 8.4 15.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RAB3GAP2_N PF14655.6 EGG17069.1 - 1.6 7.9 12.2 3.7 6.7 0.0 3.3 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BAT2_N PF07001.11 EGG17069.1 - 1.9 8.9 17.0 3.5 8.0 17.0 1.4 1 0 0 1 1 1 0 BAT2 N-terminus Macoilin PF09726.9 EGG17069.1 - 2.9 6.3 9.9 3.7 6.0 9.9 1.1 1 0 0 1 1 1 0 Macoilin family Roughex PF06020.11 EGG17069.1 - 3.1 6.8 6.9 5.3 6.0 6.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein SSP160 PF06933.11 EGG17069.1 - 3.5 5.7 13.2 4.9 5.2 13.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Presenilin PF01080.17 EGG17069.1 - 3.7 6.2 7.5 4.9 5.8 7.5 1.1 1 0 0 1 1 1 0 Presenilin Ilar_coat PF01787.16 EGG17069.1 - 5.3 6.8 8.6 11 5.8 8.6 1.4 1 0 0 1 1 1 0 Ilarvirus coat protein DUF908 PF06012.12 EGG17069.1 - 7.1 5.9 17.4 11 5.4 17.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) S36_mt PF10937.8 EGG17070.1 - 0.0088 17.6 0.2 0.017 16.7 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial PC4 PF02229.16 EGG17071.1 - 4.3e-08 32.7 0.1 6.5e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DUF2154 PF09922.9 EGG17071.1 - 0.071 13.0 0.0 0.24 11.3 0.0 1.9 2 1 1 3 3 3 0 Cell wall-active antibiotics response 4TMS YvqF WD40 PF00400.32 EGG17072.1 - 3e-23 81.7 31.1 3.2e-06 27.8 1.8 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG17072.1 - 3.6e-06 27.2 0.1 1.7 9.0 0.0 4.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PAT1 PF09770.9 EGG17072.1 - 0.027 12.8 25.7 0.044 12.1 25.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Membralin PF09746.9 EGG17072.1 - 2.4 7.1 11.7 5.1 6.0 11.7 1.6 1 0 0 1 1 1 0 Tumour-associated protein TFIIA PF03153.13 EGG17072.1 - 4.5 7.2 53.9 5.8 6.8 0.1 2.8 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Nop53 PF07767.11 EGG17072.1 - 9.9 5.4 30.5 1.9 7.8 25.8 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) UPF0020 PF01170.18 EGG17073.1 - 1.3e-06 28.2 0.0 0.042 13.5 0.0 3.1 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EGG17073.1 - 0.0034 17.1 0.0 0.0034 17.1 0.0 3.0 3 0 0 3 3 3 1 DNA methylase DDHD PF02862.17 EGG17073.1 - 8.9 6.4 8.0 16 5.6 8.0 1.4 1 0 0 1 1 1 0 DDHD domain HMG_CoA_synt_N PF01154.17 EGG17074.1 - 0.088 12.7 0.1 0.69 9.7 0.1 2.0 1 1 1 2 2 2 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal Ank_2 PF12796.7 EGG17077.1 - 2.9e-25 88.7 14.2 3.7e-05 24.2 0.0 8.1 3 3 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17077.1 - 5.3e-20 71.5 8.9 0.0015 19.1 0.0 9.7 8 1 1 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG17077.1 - 4.6e-13 49.1 11.4 0.13 12.6 0.1 11.0 10 3 4 15 15 15 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17077.1 - 1.3e-09 37.5 11.0 15 6.5 0.0 11.7 14 0 0 14 14 14 2 Ankyrin repeat Ank PF00023.30 EGG17077.1 - 0.00032 21.0 14.0 4.5 7.9 1.0 9.1 9 2 1 10 10 10 1 Ankyrin repeat PH PF00169.29 EGG17078.1 - 1.5e-14 54.4 1.2 1.5e-14 54.4 1.2 2.3 2 1 0 2 2 2 1 PH domain SH3_9 PF14604.6 EGG17078.1 - 3.2e-12 46.1 0.2 6.2e-12 45.2 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGG17078.1 - 1.7e-09 37.1 0.1 4.7e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG17078.1 - 3.7e-08 32.9 0.1 7.4e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 EGG17078.1 - 0.02 15.3 2.8 0.02 15.3 2.8 3.5 2 2 0 2 2 2 0 Pleckstrin homology domain Lin-8 PF03353.15 EGG17078.1 - 0.026 14.1 15.8 0.05 13.2 15.8 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Roughex PF06020.11 EGG17078.1 - 0.3 10.2 9.9 0.47 9.5 9.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Macoilin PF09726.9 EGG17078.1 - 0.35 9.4 18.5 0.4 9.2 18.5 1.1 1 0 0 1 1 1 0 Macoilin family Ecl1 PF12855.7 EGG17078.1 - 5.5 8.1 32.5 11 7.1 32.5 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins XPG_I PF00867.18 EGG17079.1 - 0.00093 19.5 0.6 0.005 17.2 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 EGG17079.1 - 0.017 14.6 0.0 0.072 12.6 0.0 2.0 2 0 0 2 2 2 0 XPG domain containing DUF5104 PF17117.5 EGG17079.1 - 0.41 11.1 8.5 0.18 12.2 4.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5104) Hyccin PF09790.9 EGG17080.1 - 1.5e-37 129.5 0.1 1.1e-36 126.6 0.0 2.3 2 2 0 2 2 2 1 Hyccin Tir_receptor_C PF07489.11 EGG17080.1 - 0.0014 18.7 3.6 0.0014 18.7 3.6 2.4 2 1 1 3 3 3 1 Translocated intimin receptor (Tir) C-terminus DUF3399 PF11879.8 EGG17080.1 - 0.008 16.5 0.5 0.024 15.0 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3399) Viral_env_E26 PF11050.8 EGG17080.1 - 0.11 11.8 1.3 0.24 10.7 1.3 1.5 1 0 0 1 1 1 0 Virus envelope protein E26 Med31 PF05669.12 EGG17081.1 - 1.6e-37 127.3 13.7 1.6e-37 127.3 13.7 1.5 2 0 0 2 2 2 1 SOH1 SSP160 PF06933.11 EGG17081.1 - 0.78 7.9 8.2 1.2 7.2 8.2 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Velvet PF11754.8 EGG17082.1 - 0.86 9.5 25.0 1.3 8.9 3.4 2.2 2 0 0 2 2 2 0 Velvet factor TMEM214 PF10151.9 EGG17082.1 - 8 4.8 30.6 0.024 13.1 9.8 2.2 2 0 0 2 2 2 0 TMEM214, C-terminal, caspase 4 activator Profilin PF00235.19 EGG17083.1 - 1.9e-41 141.3 0.3 2.1e-41 141.1 0.3 1.0 1 0 0 1 1 1 1 Profilin WD40 PF00400.32 EGG17085.1 - 9.2e-16 58.0 4.5 0.00031 21.5 1.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat SIR2 PF02146.17 EGG17086.1 - 8.7e-58 195.1 0.0 2.2e-57 193.9 0.0 1.7 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EGG17086.1 - 6.9e-05 22.6 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 EGG17086.1 - 0.054 13.3 0.5 0.054 13.3 0.5 2.4 2 2 1 3 3 3 0 Protein of unknown function (DUF592) BUD22 PF09073.10 EGG17086.1 - 0.37 10.1 25.0 0.52 9.6 25.0 1.2 1 0 0 1 1 1 0 BUD22 LRR_4 PF12799.7 EGG17087.1 - 0.0055 17.1 2.7 3.9 8.0 0.1 3.4 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) GDPD PF03009.17 EGG17087.1 - 0.01 15.6 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF4091 PF13320.6 EGG17088.1 - 0.045 13.9 0.1 2.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) Rad60-SLD PF11976.8 EGG17089.1 - 3.9e-15 55.4 0.7 1.6e-05 24.6 0.0 4.7 4 0 0 4 4 4 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGG17089.1 - 0.0096 15.7 0.3 4.7 7.0 0.0 4.5 5 0 0 5 5 5 1 Ubiquitin family Tudor_4 PF18358.1 EGG17089.1 - 0.13 11.9 0.7 0.56 9.8 0.2 2.4 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain TFIIA PF03153.13 EGG17089.1 - 2 8.3 20.2 5.4 6.9 20.2 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5327 PF17261.2 EGG17089.1 - 2.7 8.8 12.6 17 6.2 12.6 2.4 1 1 0 1 1 1 0 Family of unknown function (DUF5327) UCH PF00443.29 EGG17090.1 - 3.9e-52 177.3 1.0 3.9e-52 177.3 1.0 2.9 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG17090.1 - 6.5e-22 78.5 5.6 6.5e-22 78.5 5.6 3.5 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUF3439 PF11921.8 EGG17090.1 - 2.5 8.1 24.8 0.11 12.5 10.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Acetyltransf_1 PF00583.25 EGG17091.1 - 0.00038 20.7 0.0 0.0013 18.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG17091.1 - 0.016 15.6 0.0 0.12 12.8 0.0 2.5 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG17091.1 - 0.11 12.5 0.1 0.44 10.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Orf78 PF06024.12 EGG17091.1 - 5.2 7.4 7.8 15 6.0 7.8 1.7 1 0 0 1 1 1 0 Orf78 (ac78) Actin PF00022.19 EGG17092.1 - 1.9e-152 507.6 0.0 6e-152 506.0 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 EGG17093.1 - 6.4e-38 130.4 0.0 2.7e-37 128.4 0.0 1.9 1 1 0 1 1 1 1 Actin CsgF PF10614.9 EGG17093.1 - 0.14 12.4 3.4 3.5 7.9 0.5 2.3 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein Snf7 PF03357.21 EGG17094.1 - 3.3e-35 121.2 14.3 4.1e-35 120.9 14.3 1.1 1 0 0 1 1 1 1 Snf7 Aa_trans PF01490.18 EGG17094.1 - 0.0032 16.3 0.1 0.0041 15.9 0.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5082 PF16888.5 EGG17094.1 - 0.15 12.3 10.6 0.22 11.8 2.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) PspA_IM30 PF04012.12 EGG17094.1 - 0.6 9.6 14.8 0.2 11.2 2.7 2.1 2 0 0 2 2 2 0 PspA/IM30 family SYF2 PF08231.12 EGG17094.1 - 1.5 9.2 7.5 10 6.5 7.5 2.0 1 1 0 1 1 1 0 SYF2 splicing factor SlyX PF04102.12 EGG17094.1 - 1.8 9.3 16.2 4.3 8.0 2.0 3.4 3 1 0 3 3 3 0 SlyX DUF4337 PF14235.6 EGG17094.1 - 5.4 7.1 9.9 0.22 11.6 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) ArfGap PF01412.18 EGG17095.1 - 3.2e-26 91.7 0.2 3.2e-26 91.7 0.2 4.9 4 1 1 5 5 5 1 Putative GTPase activating protein for Arf zf-TRAF PF02176.18 EGG17095.1 - 0.0029 18.2 3.8 0.0076 16.9 3.8 1.7 1 0 0 1 1 1 1 TRAF-type zinc finger DM PF00751.18 EGG17095.1 - 2 8.4 10.6 0.083 12.8 2.3 2.7 1 1 1 2 2 2 0 DM DNA binding domain Imm15 PF15561.6 EGG17096.1 - 0.43 10.8 3.0 12 6.1 0.2 2.4 2 0 0 2 2 2 0 Immunity protein 15 Ribosomal_L22e PF01776.17 EGG17098.1 - 7.1e-42 142.2 2.2 1e-41 141.7 2.2 1.2 1 0 0 1 1 1 1 Ribosomal L22e protein family LAGLIDADG_1 PF00961.19 EGG17098.1 - 0.097 13.7 4.3 0.13 13.2 3.5 1.7 1 1 0 1 1 1 0 LAGLIDADG endonuclease Dimer_Tnp_hAT PF05699.14 EGG17098.1 - 0.48 10.2 2.5 0.49 10.2 1.1 1.7 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region AAA PF00004.29 EGG17099.1 - 5.2e-88 292.2 0.0 4.3e-44 150.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG17099.1 - 1.8e-21 75.7 0.4 1.4e-12 47.2 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EGG17099.1 - 1.5e-13 50.8 0.0 1.8e-05 24.5 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGG17099.1 - 7.7e-12 45.4 1.5 1.6e-05 24.9 0.0 4.0 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGG17099.1 - 3.3e-11 43.9 0.9 3.5e-05 24.2 0.2 3.8 2 2 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EGG17099.1 - 4.2e-08 33.5 0.0 0.0032 17.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGG17099.1 - 5.3e-08 33.1 0.0 0.0035 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGG17099.1 - 9.2e-08 32.4 1.8 0.018 15.3 0.1 4.3 2 2 1 4 4 4 2 AAA domain CDC48_N PF02359.18 EGG17099.1 - 4.4e-07 30.0 0.0 2.4e-05 24.4 0.0 2.5 1 1 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Mg_chelatase PF01078.21 EGG17099.1 - 8.6e-07 28.5 0.7 0.013 14.9 0.1 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EGG17099.1 - 1.1e-06 28.1 0.0 0.02 14.1 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EGG17099.1 - 5.8e-06 26.4 0.0 0.011 15.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGG17099.1 - 6.5e-06 26.5 0.0 0.17 12.3 0.0 3.2 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 EGG17099.1 - 1.3e-05 25.7 0.0 0.033 14.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EGG17099.1 - 2.3e-05 24.2 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 EGG17099.1 - 3.6e-05 24.0 0.0 0.089 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EGG17099.1 - 6.7e-05 22.7 0.0 0.011 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGG17099.1 - 8.9e-05 22.5 0.1 0.021 14.7 0.0 3.0 2 1 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 EGG17099.1 - 0.00014 21.9 0.1 0.26 11.3 0.0 2.9 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGG17099.1 - 0.00019 21.0 0.1 0.35 10.3 0.0 3.5 4 0 0 4 4 3 1 P-loop containing dynein motor region AAA_25 PF13481.6 EGG17099.1 - 0.00026 20.6 2.1 0.47 10.0 0.1 3.4 2 2 0 3 3 3 1 AAA domain NACHT PF05729.12 EGG17099.1 - 0.00033 20.6 1.7 0.09 12.7 0.0 3.8 4 0 0 4 4 4 1 NACHT domain ATPase PF06745.13 EGG17099.1 - 0.00046 19.6 0.1 0.49 9.7 0.0 2.8 2 1 0 2 2 2 2 KaiC Sigma54_activ_2 PF14532.6 EGG17099.1 - 0.00063 19.9 0.0 0.77 9.9 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 EGG17099.1 - 0.00068 20.2 0.2 0.24 11.9 0.0 3.1 2 1 1 3 3 3 1 ABC transporter AAA_3 PF07726.11 EGG17099.1 - 0.00081 19.3 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGG17099.1 - 0.0015 18.5 0.1 1 9.2 0.0 3.6 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 EGG17099.1 - 0.0024 17.1 0.0 1.4 8.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EGG17099.1 - 0.0037 17.0 0.0 0.53 10.0 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EGG17099.1 - 0.0039 16.3 0.0 0.43 9.6 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 EGG17099.1 - 0.01 16.3 0.9 1.3 9.4 0.1 3.0 3 0 0 3 3 2 1 AAA domain PhoH PF02562.16 EGG17099.1 - 0.022 14.2 0.0 1.4 8.3 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 EGG17099.1 - 0.036 13.3 0.0 8 5.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.6 EGG17099.1 - 0.041 13.6 0.9 2.2 8.0 0.1 2.7 2 1 1 3 3 3 0 AAA domain TniB PF05621.11 EGG17099.1 - 0.086 12.2 0.0 3.8 6.9 0.0 3.1 4 0 0 4 4 3 0 Bacterial TniB protein AFG1_ATPase PF03969.16 EGG17099.1 - 0.13 11.2 0.0 0.64 8.8 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase SKI PF01202.22 EGG17099.1 - 0.13 12.3 0.3 23 5.1 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase Vps4_C PF09336.10 EGG17099.1 - 0.14 12.2 0.1 6.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain RRM_1 PF00076.22 EGG17100.1 - 6.9e-08 32.2 0.1 1.1e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGG17100.1 - 1.3e-07 31.3 1.8 2.2e-07 30.6 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGG17100.1 - 0.0043 16.7 0.6 0.0091 15.7 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF2418 PF10332.9 EGG17101.1 - 2e-18 66.7 1.5 2e-18 66.7 1.5 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2418) DUF2207 PF09972.9 EGG17101.1 - 0.029 13.1 0.8 0.096 11.4 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RseC_MucC PF04246.12 EGG17101.1 - 0.042 13.8 0.5 0.042 13.8 0.5 1.9 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC S1FA PF04689.13 EGG17101.1 - 0.74 10.0 3.5 25 5.1 0.2 2.6 2 0 0 2 2 2 0 DNA binding protein S1FA Sigma_reg_N PF13800.6 EGG17101.1 - 1 9.7 6.0 5.2 7.4 0.2 3.1 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Ribosomal_S10 PF00338.22 EGG17102.1 - 1.6e-26 92.4 0.3 2e-26 92.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Rad9 PF04139.13 EGG17103.1 - 2.3e-21 76.4 0.5 2.3e-21 76.4 0.5 1.9 2 1 0 3 3 3 1 Rad9 Ank_2 PF12796.7 EGG17104.1 - 3.6e-33 114.0 16.8 2.9e-06 27.8 0.1 8.8 2 2 5 9 9 9 8 Ankyrin repeats (3 copies) BolA PF01722.18 EGG17104.1 - 2.1e-30 104.8 0.3 6.7e-30 103.2 0.3 2.0 1 0 0 1 1 1 1 BolA-like protein Ank_4 PF13637.6 EGG17104.1 - 5.8e-28 96.9 23.3 0.011 16.2 0.1 13.3 8 6 5 14 14 14 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG17104.1 - 5e-25 87.2 10.7 0.0095 16.2 0.0 15.2 7 3 8 16 16 16 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17104.1 - 2.7e-17 61.1 17.2 4.8 8.1 0.2 16.6 18 2 2 20 20 20 2 Ankyrin repeat DUF5049 PF16468.5 EGG17104.1 - 5.7e-10 38.9 1.4 1 9.3 0.0 8.4 5 2 3 8 8 8 1 Domain of unknown function (DUF5049) Ank PF00023.30 EGG17104.1 - 0.02 15.3 11.9 35 5.1 0.0 8.5 9 2 0 9 9 9 0 Ankyrin repeat Meleagrin PF08189.11 EGG17104.1 - 0.36 10.5 3.9 19 5.1 0.0 3.3 2 0 0 2 2 2 0 Meleagrin/Cygnin family Ank_2 PF12796.7 EGG17105.1 - 1.2e-19 70.6 5.9 0.017 15.7 0.2 8.1 4 2 4 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17105.1 - 5.1e-14 52.4 7.9 0.0054 17.3 0.0 11.1 10 3 2 12 12 12 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG17105.1 - 3.3e-11 43.2 0.9 17 5.9 0.0 9.3 7 3 3 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17105.1 - 2.8e-10 39.5 2.7 12 6.9 0.0 11.5 14 0 0 14 14 14 2 Ankyrin repeat EMI PF07546.13 EGG17105.1 - 0.3 11.8 3.3 47 4.8 0.0 3.7 3 0 0 3 3 3 0 EMI domain Big_9 PF17963.1 EGG17106.1 - 1e-26 93.5 110.0 2.1e-08 34.8 8.2 12.8 11 1 1 12 12 12 9 Bacterial Ig domain Cadherin_4 PF17803.1 EGG17106.1 - 1.2e-17 64.3 68.1 0.00021 21.9 2.4 10.8 10 0 0 10 10 10 8 Bacterial cadherin-like domain Cadherin_3 PF16184.5 EGG17106.1 - 2e-12 47.1 21.1 0.0014 18.6 0.1 8.3 8 0 0 8 8 8 5 Cadherin-like Cadherin_5 PF17892.1 EGG17106.1 - 2.8e-07 30.4 27.8 0.0037 17.2 1.8 8.9 8 2 0 8 8 8 2 Cadherin-like domain Laminin_EGF PF00053.24 EGG17106.1 - 1.2e-05 25.3 18.4 0.00013 22.1 8.6 2.5 1 1 1 2 2 2 2 Laminin EGF domain CelD_N PF02927.14 EGG17106.1 - 0.026 15.4 0.9 7.2 7.6 0.1 3.5 3 0 0 3 3 3 0 Cellulase N-terminal ig-like domain EGF_2 PF07974.13 EGG17106.1 - 0.17 12.3 28.2 1.1 9.7 5.8 3.5 3 0 0 3 3 3 0 EGF-like domain Big_9 PF17963.1 EGG17107.1 - 5.8e-31 107.1 103.6 2.1e-07 31.6 5.8 12.1 12 0 0 12 12 12 9 Bacterial Ig domain Cadherin_3 PF16184.5 EGG17107.1 - 1.1e-12 47.9 17.8 0.027 14.5 0.0 8.2 8 0 0 8 8 8 4 Cadherin-like Cadherin_4 PF17803.1 EGG17107.1 - 3.8e-12 46.7 85.7 0.00015 22.3 4.1 10.6 8 3 0 9 9 9 5 Bacterial cadherin-like domain Cadherin_5 PF17892.1 EGG17107.1 - 0.0026 17.7 39.2 0.092 12.7 0.3 10.0 10 3 1 11 11 11 3 Cadherin-like domain Laminin_EGF PF00053.24 EGG17107.1 - 0.0082 16.3 15.8 0.044 13.9 7.3 2.6 1 1 1 2 2 2 2 Laminin EGF domain GDP_Man_Dehyd PF16363.5 EGG17108.1 - 2.5e-23 83.0 0.0 7.1e-23 81.5 0.0 1.5 1 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG17108.1 - 3.6e-22 79.0 0.0 6.7e-22 78.1 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG17108.1 - 3.3e-12 46.0 0.0 5.5e-12 45.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGG17108.1 - 2.3e-10 40.1 0.0 5.5e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGG17108.1 - 3.4e-07 29.7 0.0 1e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGG17108.1 - 0.00021 20.5 0.0 0.057 12.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 EGG17108.1 - 0.0014 18.9 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EGG17108.1 - 0.0078 16.1 0.2 0.12 12.3 0.0 2.7 2 1 0 2 2 2 1 KR domain adh_short PF00106.25 EGG17108.1 - 0.14 11.6 0.1 12 5.3 0.0 2.6 3 0 0 3 3 3 0 short chain dehydrogenase MFS_1 PF07690.16 EGG17109.1 - 6.4e-26 91.1 33.7 6.4e-26 91.1 33.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG17109.1 - 3.7e-08 32.7 1.5 3.7e-08 32.7 1.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter RSN1_TM PF13967.6 EGG17109.1 - 0.014 15.2 2.0 0.047 13.4 0.3 2.4 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport COX5B PF01215.19 EGG17110.1 - 5e-12 45.6 0.0 8.8e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb dUTPase PF00692.19 EGG17110.1 - 0.0039 16.9 0.0 0.057 13.1 0.0 2.2 2 0 0 2 2 2 1 dUTPase zf-CHCC PF10276.9 EGG17110.1 - 0.004 17.2 0.2 0.0068 16.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger domain Kri1_C PF12936.7 EGG17111.1 - 1.4e-21 76.5 0.3 1.4e-21 76.5 0.3 5.4 5 0 0 5 5 5 1 KRI1-like family C-terminal Androgen_recep PF02166.16 EGG17111.1 - 0.94 8.2 11.0 2.1 7.1 11.0 1.6 1 0 0 1 1 1 0 Androgen receptor NUC153 PF08159.12 EGG17113.1 - 4.6e-12 45.5 1.0 9.3e-12 44.5 1.0 1.6 1 0 0 1 1 1 1 NUC153 domain TFIIF_alpha PF05793.12 EGG17113.1 - 0.54 8.8 30.6 0.77 8.3 30.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TLD PF07534.16 EGG17114.1 - 6.4e-09 36.2 0.3 8e-09 35.8 0.3 1.1 1 0 0 1 1 1 1 TLD Spt20 PF12090.8 EGG17116.1 - 0.00019 21.1 7.1 0.00022 20.9 7.1 1.1 1 0 0 1 1 1 1 Spt20 family FlbT PF07378.11 EGG17116.1 - 0.0085 16.2 0.8 0.013 15.5 0.8 1.3 1 0 0 1 1 1 1 Flagellar protein FlbT TPT PF03151.16 EGG17116.1 - 0.01 15.2 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family M_domain PF12938.7 EGG17116.1 - 0.18 11.6 20.6 0.25 11.1 20.6 1.2 1 0 0 1 1 1 0 M domain of GW182 TFIIA PF03153.13 EGG17116.1 - 0.18 11.7 11.7 0.21 11.5 11.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 EGG17116.1 - 0.62 8.9 10.6 0.73 8.7 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4834 PF16118.5 EGG17116.1 - 2.5 9.1 6.6 3.9 8.5 6.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Roughex PF06020.11 EGG17116.1 - 3.2 6.8 5.7 4 6.4 5.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Androgen_recep PF02166.16 EGG17116.1 - 8.1 5.2 14.6 9.5 4.9 14.6 1.1 1 0 0 1 1 1 0 Androgen receptor ResIII PF04851.15 EGG17119.1 - 3.8e-15 56.3 0.1 1.1e-14 54.8 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGG17119.1 - 9e-07 28.8 0.4 3.1e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 EGG17119.1 - 5.4e-06 26.3 0.4 5.4e-06 26.3 0.4 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EGG17119.1 - 0.00049 19.5 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EGG17119.1 - 0.0019 17.9 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Adeno_IVa2 PF02456.15 EGG17119.1 - 0.002 17.0 0.2 0.0048 15.8 0.1 1.7 2 0 0 2 2 2 1 Adenovirus IVa2 protein Helicase_C PF00271.31 EGG17119.1 - 0.0023 18.2 0.0 0.0095 16.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PIF1 PF05970.14 EGG17119.1 - 0.04 13.1 0.6 0.1 11.7 0.1 1.7 1 1 1 2 2 2 0 PIF1-like helicase DUF853 PF05872.12 EGG17119.1 - 0.099 11.2 0.1 0.19 10.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_5 PF07728.14 EGG17119.1 - 0.13 12.2 0.0 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RRP14 PF15459.6 EGG17119.1 - 0.96 10.1 6.6 43 4.8 0.0 3.4 3 0 0 3 3 3 0 60S ribosome biogenesis protein Rrp14 UPF0240 PF06784.11 EGG17120.1 - 4.5e-05 23.6 0.1 4.5e-05 23.6 0.1 3.1 2 2 1 3 3 3 1 Uncharacterised protein family (UPF0240) Spectrin PF00435.21 EGG17120.1 - 0.014 15.9 1.4 0.014 15.9 1.4 3.0 2 2 1 3 3 3 0 Spectrin repeat MRP-L20 PF12824.7 EGG17120.1 - 0.039 14.1 0.8 0.039 14.1 0.8 2.5 2 1 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Methyltransf_12 PF08242.12 EGG17120.1 - 3.1 8.6 5.4 14 6.5 5.1 2.4 1 1 0 1 1 1 0 Methyltransferase domain Ecm29 PF13001.7 EGG17121.1 - 3.6e-125 418.5 7.7 3.6e-125 418.5 7.7 5.2 5 1 0 5 5 5 2 Proteasome stabiliser Dynamin_M PF01031.20 EGG17121.1 - 1.3e-89 300.2 0.2 1.3e-89 300.2 0.2 2.3 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EGG17121.1 - 9e-54 182.0 0.1 4e-53 179.9 0.1 2.3 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EGG17121.1 - 9.5e-22 77.0 4.1 1.9e-20 72.8 4.2 3.2 3 0 0 3 3 3 1 Dynamin GTPase effector domain HEAT_EZ PF13513.6 EGG17121.1 - 8.8e-06 26.1 3.7 24 5.5 0.0 8.0 7 1 1 8 8 8 0 HEAT-like repeat MMR_HSR1 PF01926.23 EGG17121.1 - 4e-05 23.6 0.1 0.00019 21.5 0.1 2.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Vac14_Fab1_bd PF12755.7 EGG17121.1 - 9.2e-05 23.0 1.8 1.3 9.7 0.0 7.5 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region DUF2076 PF09849.9 EGG17121.1 - 0.0053 16.8 6.8 0.012 15.7 6.8 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) HEAT PF02985.22 EGG17121.1 - 0.03 14.6 0.7 62 4.3 0.0 6.0 6 0 0 6 6 6 0 HEAT repeat DUF2018 PF09442.10 EGG17121.1 - 2.9 8.9 5.9 5.6 8.0 1.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2018) Hydrolase_4 PF12146.8 EGG17123.1 - 4e-16 59.0 0.0 7.8e-14 51.5 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG17123.1 - 2.7e-10 41.2 0.0 3.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG17123.1 - 1.8e-09 37.6 0.0 7.3e-06 25.8 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG17123.1 - 6.3e-08 32.3 0.2 0.012 15.1 0.0 2.7 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 EGG17123.1 - 2.2e-06 27.4 0.0 0.007 15.9 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.20 EGG17123.1 - 7e-05 22.6 0.0 0.00012 21.8 0.0 1.5 2 0 0 2 2 2 1 Putative esterase AXE1 PF05448.12 EGG17123.1 - 0.00044 19.0 0.1 0.11 11.1 0.1 2.8 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 EGG17123.1 - 0.0023 17.5 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_4 PF08386.10 EGG17123.1 - 0.0027 17.8 0.0 0.0077 16.3 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_2 PF02230.16 EGG17123.1 - 0.0042 16.9 0.1 1.1 9.0 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 EGG17123.1 - 0.0086 15.7 0.1 0.018 14.7 0.1 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 EGG17123.1 - 0.012 15.4 0.0 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EGG17123.1 - 0.019 14.8 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2920 PF11144.8 EGG17123.1 - 0.036 13.3 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) PGAP1 PF07819.13 EGG17123.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF2048 PF09752.9 EGG17123.1 - 0.11 11.5 0.1 4.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Abhydrolase domain containing 18 DUF3439 PF11921.8 EGG17124.1 - 0.03 14.3 8.6 0.057 13.4 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RP-C_C PF11800.8 EGG17124.1 - 0.1 12.7 7.2 0.061 13.4 2.2 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region Mucin PF01456.17 EGG17124.1 - 0.12 12.3 13.5 0.21 11.6 13.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4471 PF14740.6 EGG17124.1 - 2.7 7.1 13.5 3.4 6.8 6.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) AATF-Che1 PF13339.6 EGG17124.1 - 2.8 8.6 17.1 7.9 7.2 8.8 2.6 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Dicty_REP PF05086.12 EGG17124.1 - 3.3 5.6 33.0 0.0098 13.9 12.5 2.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein PBP1_TM PF14812.6 EGG17124.1 - 7.1 7.1 15.9 2 8.9 11.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 EGG17124.1 - 7.6 6.3 17.4 3.5 7.4 2.4 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Fib_alpha PF08702.10 EGG17124.1 - 8.1 6.6 28.9 6.4 6.9 16.3 3.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family E2F_CC-MB PF16421.5 EGG17125.1 - 2.4e-24 85.5 0.0 2.4e-24 85.5 0.0 3.1 3 0 0 3 3 3 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 EGG17125.1 - 8.6e-19 67.4 0.1 2e-18 66.2 0.1 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain ANAPC_CDC26 PF10471.9 EGG17125.1 - 0.0056 17.5 2.4 0.0056 17.5 2.4 6.7 7 1 0 7 7 7 1 Anaphase-promoting complex APC subunit CDC26 BORCS6 PF10157.9 EGG17126.1 - 2.4e-12 47.3 3.5 2.4e-12 47.3 3.5 3.6 3 1 0 4 4 4 1 BLOC-1-related complex sub-unit 6 Rhomboid PF01694.22 EGG17127.1 - 8.7e-24 84.2 4.3 1.1e-23 83.9 4.3 1.1 1 0 0 1 1 1 1 Rhomboid family ECF_trnsprt PF12822.7 EGG17127.1 - 0.017 15.2 2.1 0.017 15.2 2.1 1.8 1 1 0 2 2 2 0 ECF transporter, substrate-specific component MTP18 PF10558.9 EGG17127.1 - 0.038 14.0 0.1 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) TspO_MBR PF03073.15 EGG17127.1 - 0.53 10.3 8.1 2.4 8.2 8.1 2.0 1 1 0 1 1 1 0 TspO/MBR family Herpes_capsid PF06112.11 EGG17128.1 - 0.3 11.1 6.8 0.39 10.8 6.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SR-25 PF10500.9 EGG17128.1 - 2.1 7.9 12.8 3.1 7.3 12.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rhomboid PF01694.22 EGG17129.1 - 8.7e-18 64.8 6.2 1e-17 64.5 6.2 1.0 1 0 0 1 1 1 1 Rhomboid family DUF5353 PF17304.2 EGG17129.1 - 0.082 12.7 0.6 0.082 12.7 0.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5353) ZZ PF00569.17 EGG17131.1 - 2.7e-07 30.3 32.0 0.00083 19.1 6.7 3.8 3 1 0 3 3 3 3 Zinc finger, ZZ type C1_2 PF03107.16 EGG17131.1 - 0.00017 21.9 24.9 0.0014 18.9 4.5 3.4 3 0 0 3 3 3 2 C1 domain Peptidase_S7 PF00949.21 EGG17131.1 - 0.019 14.8 1.7 0.051 13.4 1.7 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF4907 PF16250.5 EGG17131.1 - 0.067 13.1 0.4 0.18 11.7 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4907) zf-RING_5 PF14634.6 EGG17131.1 - 8.6 6.4 21.1 1.7 8.6 5.6 3.5 3 0 0 3 3 3 0 zinc-RING finger domain UCH PF00443.29 EGG17132.1 - 3.2e-39 135.0 21.2 3.2e-39 135.0 21.2 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG17132.1 - 1.4e-14 54.5 20.7 1.4e-14 54.5 20.7 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGG17132.1 - 3.3e-11 43.6 29.0 1.5e-05 25.5 0.1 6.2 6 1 0 6 6 6 3 DUSP domain ubiquitin PF00240.23 EGG17132.1 - 5.7e-07 29.2 0.1 2.4e-06 27.2 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin family Dickkopf_N PF04706.12 EGG17133.1 - 0.00025 21.5 23.7 0.0016 18.9 12.4 6.7 4 2 3 7 7 7 4 Dickkopf N-terminal cysteine-rich region Ctr PF04145.15 EGG17134.1 - 0.12 13.0 2.0 0.13 12.9 0.1 1.9 2 0 0 2 2 2 0 Ctr copper transporter family PA26 PF04636.13 EGG17134.1 - 1.2 8.0 5.5 2.1 7.2 3.1 1.9 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) PROCN PF08083.11 EGG17135.1 - 5.5e-231 766.4 9.2 8.6e-231 765.7 9.2 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EGG17135.1 - 5.3e-127 422.1 0.6 9.5e-127 421.3 0.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EGG17135.1 - 8.4e-88 292.3 3.5 2.1e-87 291.0 3.5 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EGG17135.1 - 2.6e-84 280.7 4.4 5.5e-84 279.6 4.4 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EGG17135.1 - 1.6e-70 235.4 0.1 3.1e-70 234.5 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EGG17135.1 - 9.9e-46 154.0 0.3 2.7e-45 152.6 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EGG17135.1 - 1.4e-44 150.9 1.0 4.2e-44 149.4 1.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 EGG17135.1 - 6.1e-07 29.4 0.0 2.3e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Guanylate_cyc PF00211.20 EGG17136.1 - 1.5e-55 187.7 0.1 2.2e-55 187.1 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CHASE PF03924.13 EGG17136.1 - 6e-07 29.6 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 CHASE domain TRAPP PF04051.16 EGG17136.1 - 0.026 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component LAP1C PF05609.12 EGG17136.1 - 0.13 11.3 5.2 0.29 10.2 5.2 1.5 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peroxin-3 PF04882.12 EGG17136.1 - 1.5 7.7 10.0 0.041 12.9 2.8 2.0 2 0 0 2 2 2 0 Peroxin-3 FGase PF05013.12 EGG17137.1 - 0.029 14.6 0.2 14 5.9 0.0 3.1 2 1 0 2 2 2 0 N-formylglutamate amidohydrolase PWWP PF00855.17 EGG17138.1 - 1.2e-06 28.8 0.1 1.2e-06 28.8 0.1 3.9 4 0 0 4 4 4 1 PWWP domain HTH_5 PF01022.20 EGG17138.1 - 0.045 13.6 0.2 0.09 12.7 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family ERGIC_N PF13850.6 EGG17140.1 - 6.1e-05 23.3 0.0 6.3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Lipin_N PF04571.14 EGG17140.1 - 0.032 14.2 0.0 0.032 14.2 0.0 1.0 1 0 0 1 1 1 0 lipin, N-terminal conserved region COPIIcoated_ERV PF07970.12 EGG17141.1 - 2.5e-88 295.7 0.3 3.5e-88 295.2 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGG17141.1 - 1.9e-13 50.6 0.8 5.2e-13 49.1 0.1 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Exo_endo_phos PF03372.23 EGG17143.1 - 5.5e-13 49.0 0.0 1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ank_5 PF13857.6 EGG17144.1 - 3.9e-13 49.3 2.2 1.3e-06 28.5 0.1 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG17144.1 - 3.6e-11 43.4 3.0 0.00022 21.7 0.0 3.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG17144.1 - 6e-11 42.8 6.4 1.5e-09 38.3 2.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGG17144.1 - 3e-06 27.4 0.6 0.08 13.4 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EGG17144.1 - 2.7e-05 24.2 1.5 0.53 11.0 0.1 4.1 4 1 1 5 5 5 2 Ankyrin repeat ETRAMP PF09716.10 EGG17144.1 - 0.00051 20.0 2.9 0.89 9.7 2.1 2.7 2 0 0 2 2 2 2 Malarial early transcribed membrane protein (ETRAMP) PSI PF01437.25 EGG17144.1 - 0.00086 19.8 11.8 0.002 18.6 11.8 1.7 1 0 0 1 1 1 1 Plexin repeat LisH_TPL PF17814.1 EGG17144.1 - 0.082 12.6 0.4 9.4 6.0 0.1 2.8 3 0 0 3 3 3 0 LisH-like dimerisation domain DUF5381 PF17353.2 EGG17144.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5381) Flagellin_C PF00700.21 EGG17144.1 - 0.29 11.5 3.9 7.9 6.9 0.7 3.2 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region TROVE PF05731.11 EGG17145.1 - 2.2e-80 270.9 1.7 5.7e-75 253.0 1.3 3.4 1 1 1 2 2 2 2 TROVE domain WD40 PF00400.32 EGG17145.1 - 6e-72 235.8 58.6 3.8e-07 30.7 0.7 19.9 19 0 0 19 19 19 16 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG17145.1 - 4.4e-32 110.2 10.7 0.00019 21.7 0.0 12.5 6 5 5 12 12 12 7 Anaphase-promoting complex subunit 4 WD40 domain DUF4062 PF13271.6 EGG17145.1 - 4.2e-20 71.9 0.0 2.5e-19 69.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) WD40_like PF17005.5 EGG17145.1 - 2e-18 66.7 18.6 2e-09 37.2 2.1 6.3 4 1 2 6 6 6 4 WD40-like domain Ge1_WD40 PF16529.5 EGG17145.1 - 1.2e-07 31.0 11.5 0.018 14.0 0.0 7.6 4 4 5 9 9 9 2 WD40 region of Ge1, enhancer of mRNA-decapping protein APAF1_C PF17908.1 EGG17145.1 - 8.6e-06 25.8 9.8 0.013 15.5 0.5 3.4 3 0 0 3 3 3 2 APAF-1 helical domain PD40 PF07676.12 EGG17145.1 - 0.0036 17.2 0.9 54 3.9 0.0 5.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 EGG17145.1 - 0.0059 15.0 1.2 4.1 5.6 0.0 4.5 4 1 1 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 EGG17145.1 - 0.054 12.0 0.2 9.2 4.7 0.0 3.8 4 1 1 5 5 5 0 Cytochrome D1 heme domain TFIIIC_delta PF12657.7 EGG17145.1 - 2.6 7.9 10.9 3.7 7.4 0.8 4.2 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Adaptin_N PF01602.20 EGG17148.1 - 1.2e-79 268.3 8.8 1.7e-79 267.8 8.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGG17148.1 - 2e-28 99.5 0.2 4e-27 95.2 0.0 3.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 EGG17148.1 - 4.3e-16 59.0 0.0 1.7e-15 57.1 0.0 2.1 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.22 EGG17148.1 - 2.8e-05 24.0 0.0 0.71 10.3 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 EGG17148.1 - 0.00062 20.1 0.0 0.057 13.8 0.0 2.7 1 1 1 2 2 2 2 HEAT repeats RRP36 PF06102.12 EGG17148.1 - 0.093 12.7 2.4 0.21 11.5 2.4 1.5 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF1985 PF09331.11 EGG17148.1 - 3.3 7.7 6.8 11 6.0 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1985) DDE_Tnp_1_7 PF13843.6 EGG17149.1 - 3.6e-17 62.7 0.0 7.2e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Transposase IS4 Mpp10 PF04006.12 EGG17149.1 - 0.51 8.7 21.9 0.77 8.1 21.9 1.2 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 EGG17149.1 - 1.6 6.9 18.9 2.4 6.4 18.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BLM10_N PF16547.5 EGG17149.1 - 3.6 7.9 5.0 0.88 9.9 1.3 1.9 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, N-terminal YL1 PF05764.13 EGG17149.1 - 4 7.5 21.0 7.1 6.7 21.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CPSF100_C PF13299.6 EGG17149.1 - 5.8 7.1 6.7 10 6.3 6.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CobT PF06213.12 EGG17149.1 - 5.9 6.2 17.9 9.4 5.5 17.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CKAP2_C PF15297.6 EGG17149.1 - 8.9 5.3 11.7 14 4.6 11.7 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Sin_N PF04801.13 EGG17149.1 - 9 5.4 10.9 13 4.8 10.9 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region DEAD PF00270.29 EGG17151.1 - 1.3e-42 145.5 0.0 3.9e-42 144.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG17151.1 - 8.8e-28 96.9 3.1 3.7e-26 91.6 0.4 3.3 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG17151.1 - 1.4e-08 34.9 0.1 1.7e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGG17151.1 - 0.011 15.1 0.0 0.029 13.7 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 EGG17151.1 - 0.027 13.7 0.2 0.051 12.8 0.2 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PRK PF00485.18 EGG17151.1 - 0.14 11.8 1.3 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SprA-related PF12118.8 EGG17151.1 - 0.99 8.5 10.1 2 7.5 10.1 1.4 1 0 0 1 1 1 0 SprA-related family DUF4286 PF14114.6 EGG17152.1 - 9e-23 80.6 0.2 1e-22 80.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) Pga1 PF10333.9 EGG17153.1 - 0.00024 21.0 0.4 0.00053 19.9 0.3 1.7 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Endotoxin_C PF03944.14 EGG17153.1 - 0.023 15.0 1.7 0.041 14.2 1.7 1.4 1 0 0 1 1 1 0 delta endotoxin TPR_1 PF00515.28 EGG17154.1 - 1.7e-08 33.9 2.8 0.0025 17.6 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat SET PF00856.28 EGG17154.1 - 8.8e-08 32.7 0.0 2.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 SET domain TPR_2 PF07719.17 EGG17154.1 - 8.5e-06 25.5 3.0 0.044 13.9 0.2 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG17154.1 - 0.0024 17.9 1.2 0.0087 16.1 0.2 2.5 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 EGG17154.1 - 0.0099 15.6 2.7 5.9 6.7 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 EGG17154.1 - 0.023 15.2 1.2 0.053 14.0 0.3 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG17154.1 - 0.041 14.5 0.7 12 6.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGG17154.1 - 0.041 13.7 1.9 0.53 10.2 0.2 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat RPN7 PF10602.9 EGG17154.1 - 0.045 13.5 1.7 0.075 12.7 0.0 2.2 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_12 PF13424.6 EGG17154.1 - 0.054 13.8 7.0 0.058 13.7 2.4 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat AbiEi_4 PF13338.6 EGG17154.1 - 0.19 11.9 0.2 21 5.3 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin TPR_8 PF13181.6 EGG17154.1 - 0.2 11.9 6.1 24 5.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG17154.1 - 0.21 11.7 2.1 0.78 9.9 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-RVT PF13966.6 EGG17155.1 - 0.00027 21.6 0.6 0.0008 20.1 0.6 1.8 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Arf PF00025.21 EGG17157.1 - 8.2e-69 230.5 0.1 9.8e-69 230.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG17157.1 - 5.4e-16 58.9 0.0 7.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG17157.1 - 4.6e-12 45.8 0.0 5.1e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EGG17157.1 - 3.5e-11 42.9 0.6 1.8e-08 34.0 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGG17157.1 - 2e-10 40.4 0.0 2.4e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGG17157.1 - 1.8e-07 30.8 0.0 2.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG17157.1 - 7.4e-05 22.8 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG17157.1 - 0.021 14.4 0.4 0.32 10.5 0.1 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EGG17157.1 - 0.051 13.7 0.1 0.26 11.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain 6PF2K PF01591.18 EGG17157.1 - 0.17 11.2 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Ank_2 PF12796.7 EGG17158.1 - 1.9e-09 38.0 0.2 0.021 15.4 0.0 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17158.1 - 5.3e-09 36.5 1.3 0.014 16.0 0.0 4.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17158.1 - 1.2e-06 28.4 0.5 23 6.0 0.1 6.3 4 2 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EGG17158.1 - 2.2e-06 27.8 0.2 1.2 9.6 0.0 5.6 3 2 2 5 5 5 1 Ankyrin repeats (many copies) RPN1_RPN2_N PF17781.1 EGG17159.1 - 8.4e-115 383.4 0.5 1.2e-114 382.9 0.5 1.2 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain DAO PF01266.24 EGG17159.1 - 1.5e-33 116.8 0.0 2.5e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase RPN1_C PF18051.1 EGG17159.1 - 3.7e-30 103.7 0.0 9.3e-30 102.5 0.0 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EGG17159.1 - 4.7e-23 80.4 18.0 0.00083 19.7 1.3 9.9 10 0 0 10 10 10 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGG17159.1 - 1.7e-05 25.1 0.0 0.011 16.2 0.1 3.5 3 0 0 3 3 3 1 HEAT repeats Phage_r1t_holin PF16945.5 EGG17161.1 - 0.11 12.7 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin CsbD PF05532.12 EGG17162.1 - 0.013 15.4 1.4 0.036 14.0 0.6 1.9 2 0 0 2 2 2 0 CsbD-like ubiquitin PF00240.23 EGG17163.1 - 1.8e-11 43.6 0.0 7.1e-11 41.7 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 EGG17163.1 - 0.0013 19.3 0.2 0.014 16.0 0.1 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGG17163.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Dickkopf_N PF04706.12 EGG17164.1 - 0.0062 17.0 20.7 0.012 16.1 9.7 5.6 5 2 1 6 6 6 4 Dickkopf N-terminal cysteine-rich region DCP2 PF05026.13 EGG17165.1 - 6.4e-14 52.0 1.4 6.4e-14 52.0 1.4 3.3 2 1 1 3 3 3 1 Dcp2, box A domain NUDIX PF00293.28 EGG17165.1 - 1.1e-11 44.8 0.1 4.3e-11 43.0 0.1 2.0 1 0 0 1 1 1 1 NUDIX domain DUF3439 PF11921.8 EGG17165.1 - 0.19 11.7 8.2 0.34 10.9 6.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGG17165.1 - 4.1 7.4 18.1 0.043 13.8 9.6 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein FAD_SOX PF18371.1 EGG17166.1 - 0.081 13.3 0.0 1.6 9.1 0.0 2.1 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF4859 PF16151.5 EGG17166.1 - 0.42 10.5 1.4 7.6 6.4 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4859) TIG PF01833.24 EGG17167.1 - 0.00011 22.1 4.4 0.0061 16.6 0.1 3.9 2 1 0 2 2 2 1 IPT/TIG domain Orf78 PF06024.12 EGG17167.1 - 0.0075 16.6 17.8 0.21 11.9 3.5 3.9 2 1 2 4 4 4 2 Orf78 (ac78) LRRC37AB_C PF14914.6 EGG17167.1 - 0.012 15.5 2.7 1.7 8.5 0.1 3.1 3 0 0 3 3 3 0 LRRC37A/B like protein 1 C-terminal domain Connexin PF00029.19 EGG17167.1 - 0.028 14.2 0.8 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Connexin BTP PF05232.12 EGG17167.1 - 0.14 12.2 1.6 0.43 10.7 1.6 1.8 1 0 0 1 1 1 0 Chlorhexidine efflux transporter CSG2 PF16965.5 EGG17167.1 - 0.3 10.0 10.3 0.24 10.3 6.3 2.3 2 1 0 2 2 2 0 Ceramide synthase regulator Oxidored_q3 PF00499.20 EGG17167.1 - 0.36 10.5 1.9 14 5.4 0.0 2.5 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 EOS1 PF12326.8 EGG17167.1 - 0.44 10.4 5.9 29 4.5 0.0 2.4 2 0 0 2 2 2 0 N-glycosylation protein Presenilin PF01080.17 EGG17167.1 - 0.69 8.6 7.3 19 3.9 0.0 2.3 2 0 0 2 2 2 0 Presenilin SPX PF03105.19 EGG17167.1 - 0.96 9.3 14.9 0.92 9.4 8.5 2.2 2 0 0 2 2 2 0 SPX domain Serinc PF03348.15 EGG17167.1 - 1.2 8.0 6.6 4.5 6.1 5.9 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) Velvet PF11754.8 EGG17167.1 - 3.8 7.4 12.5 8.7 6.2 7.6 2.3 2 0 0 2 2 2 0 Velvet factor ETRAMP PF09716.10 EGG17167.1 - 4.3 7.5 8.4 0.27 11.3 0.8 2.8 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) SR-25 PF10500.9 EGG17167.1 - 4.8 6.7 22.0 0.19 11.3 13.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Zip PF02535.22 EGG17167.1 - 7 5.8 10.5 2.4 7.3 5.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Anoctamin PF04547.12 EGG17168.1 - 2.7e-22 79.3 16.1 6.1e-22 78.1 16.1 1.5 1 1 0 1 1 1 1 Calcium-activated chloride channel TMC PF07810.13 EGG17168.1 - 1.3e-10 41.8 0.1 1.3e-10 41.8 0.1 3.1 2 2 1 3 3 3 1 TMC domain RSN1_7TM PF02714.15 EGG17168.1 - 1.3e-05 24.6 13.6 6.3e-05 22.4 13.6 2.1 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate HRG PF16954.5 EGG17168.1 - 0.028 14.8 5.6 0.13 12.7 5.6 2.2 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene CDP-OH_P_transf PF01066.21 EGG17169.1 - 6.5e-15 55.7 0.1 6.5e-15 55.7 0.1 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase EXS PF03124.14 EGG17170.1 - 2.8e-66 224.1 36.8 4e-66 223.6 36.8 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EGG17170.1 - 1.1e-06 28.9 1.7 1.1e-06 28.9 1.7 4.9 3 1 0 3 3 3 1 SPX domain COX14 PF14880.6 EGG17170.1 - 0.059 13.2 0.5 0.24 11.3 0.5 2.0 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Abhydrolase_1 PF00561.20 EGG17171.1 - 7.7e-15 55.2 0.4 3.7e-13 49.7 0.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG17171.1 - 1.3e-08 34.5 0.0 2.7e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG17171.1 - 1.3e-05 25.9 0.0 1.6e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 EGG17171.1 - 0.0019 18.2 0.0 0.0063 16.5 0.0 1.9 1 1 0 1 1 1 1 Cutinase PTEN_C2 PF10409.9 EGG17171.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein LIM_bind PF01803.16 EGG17172.1 - 1.8e-43 148.8 0.0 1.8e-43 148.8 0.0 8.9 4 3 0 4 4 4 1 LIM-domain binding protein FNIP PF05725.12 EGG17173.1 - 0.00051 20.2 5.7 4.5 7.5 1.2 4.9 3 2 0 3 3 3 3 FNIP Repeat AhpC-TSA PF00578.21 EGG17174.1 - 3.3e-41 140.1 0.0 5.5e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGG17174.1 - 1.5e-25 89.6 0.1 2e-25 89.2 0.1 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EGG17174.1 - 1.2e-05 25.6 0.0 2.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like dUTPase PF00692.19 EGG17175.1 - 2.5e-08 33.7 0.0 5.2e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 dUTPase FA_hydroxylase PF04116.13 EGG17176.1 - 2.5e-26 92.6 11.9 2.5e-26 92.6 11.9 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Snf7 PF03357.21 EGG17177.1 - 1.5e-26 93.0 22.3 1.5e-26 93.0 22.3 2.8 3 0 0 3 3 3 1 Snf7 Nucleocap_ssRNA PF11128.8 EGG17177.1 - 0.0079 15.9 1.2 0.66 9.7 0.2 3.1 2 1 1 3 3 3 1 Plant viral coat protein nucleocapsid ToxB_N PF18224.1 EGG17177.1 - 0.022 14.7 0.6 0.055 13.4 0.6 1.6 1 0 0 1 1 1 0 ToxB N-terminal domain CODH_A_N PF18537.1 EGG17177.1 - 0.028 14.4 0.7 7.8 6.6 0.0 3.5 4 1 0 4 4 4 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain DUF3439 PF11921.8 EGG17177.1 - 0.18 11.8 1.3 0.35 10.8 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF3439 PF11921.8 EGG17178.1 - 0.052 13.5 3.5 0.087 12.8 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) STATa_Ig PF18214.1 EGG17179.1 - 2.4e-47 159.9 0.9 2.4e-47 159.9 0.9 2.7 2 0 0 2 2 2 1 STATa Immunoglobulin-like domain EF-hand_12 PF17901.1 EGG17179.1 - 2.9e-41 139.8 0.9 2.9e-41 139.8 0.9 3.3 3 0 0 3 3 3 1 EF-hand fold domain Dict-STAT-coil PF09267.10 EGG17179.1 - 3.6e-37 127.2 15.9 3.6e-37 127.2 15.9 4.5 3 1 1 5 5 5 1 Dictyostelium STAT, coiled coil SH2 PF00017.24 EGG17179.1 - 1.1e-11 44.7 0.0 7.2e-11 42.0 0.0 2.5 1 0 0 1 1 1 1 SH2 domain SDA1 PF05285.12 EGG17179.1 - 0.28 10.6 13.3 0.58 9.5 13.3 1.5 1 0 0 1 1 1 0 SDA1 Melibiase_2 PF16499.5 EGG17180.1 - 1e-60 205.4 7.8 1.5e-60 204.8 7.8 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EGG17180.1 - 2.8e-17 62.5 0.0 1.4e-16 60.3 0.0 2.2 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 EGG17180.1 - 8e-07 29.2 0.0 2.8e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 EGG17180.1 - 0.00077 18.5 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Melibiase SRP9-21 PF05486.12 EGG17181.1 - 5.3e-08 33.1 0.4 4.6e-06 26.9 0.4 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF3430 PF11912.8 EGG17182.1 - 1.7e-10 41.3 15.7 2e-10 41.1 15.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGG17182.1 - 0.0024 18.1 4.2 0.33 11.2 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3586) CI-B14_5a PF07347.12 EGG17183.1 - 0.011 15.6 0.8 0.022 14.6 0.8 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF778 PF05608.12 EGG17185.1 - 0.015 15.7 0.1 0.017 15.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) SNF2_N PF00176.23 EGG17186.1 - 5.2e-68 229.3 1.7 1.1e-67 228.3 1.7 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG17186.1 - 1.7e-20 73.4 0.0 6.9e-20 71.5 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 EGG17186.1 - 1.9e-15 56.5 13.2 1.2e-09 37.9 3.1 3.6 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 EGG17186.1 - 4.5e-15 55.9 0.3 4.5e-15 55.9 0.3 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) ResIII PF04851.15 EGG17186.1 - 4.1e-12 46.4 0.0 4.1e-12 46.4 0.0 4.1 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 EGG17186.1 - 0.00015 21.8 0.1 0.0021 18.1 0.0 3.1 2 0 0 2 2 2 1 SLIDE Myb_DNA-binding PF00249.31 EGG17186.1 - 0.027 14.7 0.5 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain HEXIM PF15313.6 EGG17187.1 - 0.00096 19.4 4.0 0.00096 19.4 4.0 1.6 1 1 1 2 2 2 1 Hexamethylene bis-acetamide-inducible protein Amidohydro_2 PF04909.14 EGG17188.1 - 1.3e-05 25.2 0.0 0.0016 18.2 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase AreA_N PF07573.11 EGG17188.1 - 0.12 13.0 0.4 0.58 10.8 0.4 2.2 1 0 0 1 1 1 0 Nitrogen regulatory protein AreA N terminus Choline_transpo PF04515.12 EGG17189.1 - 2.5e-78 263.5 32.3 2.5e-78 263.5 32.3 2.7 2 1 0 2 2 2 1 Plasma-membrane choline transporter Pilin_N PF07790.11 EGG17189.1 - 3.6 8.6 5.5 21 6.1 0.2 3.1 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal F-box PF00646.33 EGG17191.1 - 0.078 12.9 0.5 0.21 11.5 0.5 1.8 1 0 0 1 1 1 0 F-box domain PP2 PF14299.6 EGG17191.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.6 1 1 0 1 1 1 0 Phloem protein 2 PP2 PF14299.6 EGG17192.1 - 0.016 15.3 0.0 0.059 13.4 0.0 2.1 1 1 0 1 1 1 0 Phloem protein 2 Pox_Ag35 PF03286.14 EGG17192.1 - 0.7 9.7 7.3 1.1 9.0 7.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Astro_capsid_p PF12226.8 EGG17192.1 - 2.7 7.0 14.2 3.8 6.6 14.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF3295 PF11702.8 EGG17192.1 - 2.9 7.1 8.5 3.8 6.8 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) MMR_HSR1_Xtn PF16897.5 EGG17194.1 - 1.5e-40 137.5 0.3 2.7e-40 136.7 0.3 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EGG17194.1 - 1.3e-21 76.4 0.1 2.1e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EGG17194.1 - 1.7e-20 73.2 0.0 3.5e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG17194.1 - 6.7e-09 35.5 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGG17194.1 - 0.0027 17.8 0.0 0.33 11.0 0.0 2.5 1 1 1 2 2 2 1 Dynamin family KTI12 PF08433.10 EGG17194.1 - 0.014 14.9 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Roc PF08477.13 EGG17194.1 - 0.065 13.5 0.1 0.46 10.7 0.0 2.3 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EGG17194.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.10 EGG17194.1 - 0.087 12.2 0.1 0.29 10.5 0.1 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MeaB PF03308.16 EGG17194.1 - 0.11 11.5 0.1 0.34 9.9 0.1 1.9 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EGG17194.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGG17194.1 - 0.13 12.2 0.2 0.53 10.2 0.1 2.1 2 1 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 EGG17194.1 - 0.18 12.0 0.1 0.39 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain PfkB PF00294.24 EGG17196.1 - 1e-16 61.2 0.6 7e-13 48.5 0.0 3.4 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Branch PF02485.21 EGG17196.1 - 8.9e-14 51.6 8.2 8.9e-14 51.6 8.2 2.7 3 1 0 3 3 3 1 Core-2/I-Branching enzyme DUF507 PF04368.13 EGG17196.1 - 0.015 15.2 0.1 0.044 13.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF507) Mak16 PF04874.14 EGG17196.1 - 0.017 15.7 9.3 0.3 11.7 0.2 3.6 3 0 0 3 3 3 0 Mak16 protein C-terminal region YjgF_endoribonc PF14588.6 EGG17196.1 - 0.029 14.5 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Med3 PF11593.8 EGG17196.1 - 1.5 8.0 13.0 0.047 12.9 5.4 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Sh_2 PF17512.2 EGG17196.1 - 2.2 8.1 10.3 3.6 7.3 10.3 1.3 1 0 0 1 1 1 0 Metapneumovirus Small hydrophobic protein Mucin PF01456.17 EGG17196.1 - 9.1 6.3 15.9 16 5.5 15.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1295 PF06966.12 EGG17197.1 - 1.2e-46 159.2 5.6 9.8e-32 110.4 0.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EGG17197.1 - 2.2e-05 24.5 1.8 2.2e-05 24.5 1.8 2.2 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EGG17197.1 - 0.0012 19.2 0.7 0.0012 19.2 0.7 2.3 3 1 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 EGG17197.1 - 0.0029 16.5 3.2 0.012 14.4 1.8 2.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Yip1 PF04893.17 EGG17197.1 - 0.0043 16.8 6.0 0.0056 16.4 0.1 2.4 2 1 0 2 2 2 1 Yip1 domain PEMT PF04191.13 EGG17197.1 - 0.0095 16.3 0.5 0.0095 16.3 0.5 2.8 3 1 0 3 3 3 1 Phospholipid methyltransferase Cas6b_C PF17262.2 EGG17197.1 - 0.064 13.4 0.4 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 Cas6b C-terminal domain NAD1 PF18778.1 EGG17198.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 DUF2039 PF10217.9 EGG17199.1 - 1.8e-26 92.3 15.8 1.8e-26 92.3 15.8 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) zinc-ribbons_6 PF07191.12 EGG17199.1 - 0.0019 18.1 10.4 0.0041 17.1 10.4 1.5 1 0 0 1 1 1 1 zinc-ribbons Paired_CXXCH_1 PF09699.10 EGG17199.1 - 0.03 14.1 0.4 0.03 14.1 0.4 3.3 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) FhuF_C PF11575.8 EGG17199.1 - 0.31 11.0 3.9 19 5.3 0.0 3.3 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain DZR PF12773.7 EGG17199.1 - 3 7.9 11.8 3.6 7.7 7.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 EGG17199.1 - 3.9 7.5 17.3 0.21 11.6 1.1 3.1 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DiS_P_DiS PF06750.13 EGG17199.1 - 8.6 6.6 7.1 3.3 7.9 3.3 2.0 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Cellulase PF00150.18 EGG17200.1 - 6.4e-31 107.8 0.0 9.8e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EGG17200.1 - 9.1e-15 55.0 0.1 1.6e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_1 PF00232.18 EGG17200.1 - 0.031 12.7 0.0 0.052 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Ricin_B_lectin PF00652.22 EGG17201.1 - 9.2e-13 48.6 0.2 1.9e-12 47.6 0.2 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EGG17201.1 - 6e-10 39.7 4.7 1.6e-07 31.9 0.7 3.6 3 1 1 4 4 4 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 EGG17201.1 - 1.3e-05 24.8 0.7 5.9e-05 22.7 0.3 2.3 1 1 1 2 2 2 1 Cytolethal distending toxin A/C domain Endotoxin_N PF03945.14 EGG17202.1 - 0.016 14.9 0.2 0.12 12.1 0.2 2.3 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain SurA_N_3 PF13624.6 EGG17202.1 - 0.036 13.9 0.7 0.36 10.6 0.0 2.2 1 1 1 2 2 2 0 SurA N-terminal domain ImcF-related_N PF14331.6 EGG17202.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 ImcF-related N-terminal domain DUF2680 PF10925.8 EGG17202.1 - 5.3 7.1 10.6 0.49 10.4 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) ILEI PF15711.5 EGG17203.1 - 2.6e-09 37.4 9.2 0.00025 21.5 0.1 4.4 4 0 0 4 4 4 2 Interleukin-like EMT inducer DUF1400 PF07176.11 EGG17203.1 - 0.036 14.4 1.0 0.075 13.3 1.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) Xpo1 PF08389.12 EGG17204.1 - 3e-10 40.3 4.1 3e-10 40.3 4.1 6.9 5 1 1 6 6 6 1 Exportin 1-like protein IBN_N PF03810.19 EGG17204.1 - 2.3e-08 33.8 16.2 7.1e-06 25.8 1.4 4.5 3 0 0 3 3 3 2 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 EGG17204.1 - 6.7e-08 32.5 0.0 4.1e-07 29.9 0.0 2.5 2 0 0 2 2 2 1 Importin 13 repeat Arm PF00514.23 EGG17204.1 - 0.00011 22.0 3.9 0.18 11.9 0.0 6.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EGG17204.1 - 0.0061 16.6 0.3 0.0061 16.6 0.3 5.8 6 2 2 8 8 8 2 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.6 EGG17204.1 - 0.0076 16.5 0.0 0.14 12.4 0.0 3.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.6 EGG17204.1 - 0.0076 16.6 0.0 0.13 12.6 0.0 3.0 3 0 0 3 3 3 1 HEAT repeats Miga PF10265.9 EGG17206.1 - 1.5 7.7 20.9 0.9 8.4 17.2 1.9 2 0 0 2 2 2 0 Mitoguardin MDFI PF15316.6 EGG17206.1 - 2.3 8.3 12.9 0.088 12.9 6.1 2.0 2 0 0 2 2 2 0 MyoD family inhibitor MAP70 PF07058.11 EGG17206.1 - 5.2 5.7 8.0 7.1 5.2 8.0 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 CLPTM1 PF05602.12 EGG17207.1 - 0.016 14.3 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) TLD PF07534.16 EGG17208.1 - 2.5e-35 121.7 0.6 9.1e-35 119.9 0.6 2.0 1 0 0 1 1 1 1 TLD hSac2 PF12456.8 EGG17208.1 - 5.1e-05 23.0 0.4 0.12 12.1 0.0 3.2 3 0 0 3 3 3 2 Inositol phosphatase Folliculin PF11704.8 EGG17208.1 - 0.36 10.7 5.9 1.6 8.6 0.0 2.7 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport VCBS PF13517.6 EGG17210.1 - 7.9e-21 74.4 25.5 2.3e-09 37.7 2.2 5.9 3 2 2 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGG17210.1 - 2.7e-08 33.8 21.0 0.079 13.1 0.1 6.1 6 0 0 6 6 6 4 FG-GAP repeat Cytomega_TRL10 PF06084.11 EGG17210.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein TcdB_toxin_midN PF12256.8 EGG17210.1 - 0.034 13.5 0.1 12 5.2 0.0 3.1 4 0 0 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region DUF4381 PF14316.6 EGG17210.1 - 0.24 11.6 0.0 0.4 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) MRP_L53 PF10780.9 EGG17211.1 - 0.00061 19.9 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF1829 PF08862.10 EGG17211.1 - 0.043 14.3 1.2 0.91 10.1 1.2 2.1 1 1 0 1 1 1 0 Domain of unknown function DUF1829 PDDEXK_1 PF12705.7 EGG17211.1 - 0.049 13.5 0.0 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily RRM_1 PF00076.22 EGG17212.1 - 1.4e-23 82.5 0.8 6.4e-12 45.1 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG17212.1 - 6.1e-06 26.3 4.9 0.048 13.8 0.0 3.7 3 2 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EGG17212.1 - 0.0015 18.5 1.0 0.17 11.9 0.0 2.8 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif VWA_2 PF13519.6 EGG17215.1 - 2.5e-11 44.2 1.9 2.5e-11 44.2 1.9 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain TMEM51 PF15345.6 EGG17215.1 - 0.025 14.5 7.5 0.19 11.5 0.2 2.6 3 0 0 3 3 3 0 Transmembrane protein 51 RPW8 PF05659.11 EGG17215.1 - 0.025 14.3 1.1 0.28 10.9 0.1 2.8 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Med3 PF11593.8 EGG17215.1 - 0.72 9.0 27.4 0.041 13.1 9.4 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Orthopox_F8 PF05886.11 EGG17215.1 - 3 8.0 9.1 0.83 9.8 0.9 3.1 3 0 0 3 3 3 0 Orthopoxvirus F8 protein FPP PF05911.11 EGG17216.1 - 0.0021 16.3 9.6 0.0029 15.9 9.6 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Tropomyosin_1 PF12718.7 EGG17216.1 - 0.02 15.1 16.9 0.36 11.0 0.5 2.2 2 0 0 2 2 2 0 Tropomyosin like Atg14 PF10186.9 EGG17216.1 - 0.049 12.7 8.6 0.073 12.1 8.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAP1_N PF04849.13 EGG17216.1 - 0.069 12.3 15.1 0.13 11.4 15.1 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 EGG17216.1 - 0.17 11.2 1.9 0.22 10.9 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MtrG PF04210.13 EGG17216.1 - 0.2 11.5 0.6 0.5 10.3 0.2 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G CC2-LZ PF16516.5 EGG17216.1 - 0.43 11.0 14.7 0.18 12.2 8.2 2.4 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 EGG17216.1 - 0.49 9.2 13.9 0.76 8.6 13.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5320 PF17253.2 EGG17216.1 - 0.71 11.0 6.2 12 7.0 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5320) V_ATPase_I PF01496.19 EGG17216.1 - 1.7 6.5 6.4 2.3 6.0 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vfa1 PF08432.10 EGG17216.1 - 2 8.7 14.1 0.3 11.4 10.0 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CENP-Q PF13094.6 EGG17216.1 - 2.8 8.1 16.0 6.1 7.0 0.5 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.12 EGG17216.1 - 5.1 7.8 17.1 1.4 9.6 3.5 3.0 2 1 1 3 3 3 0 SlyX TPR_1 PF00515.28 EGG17217.1 - 0.00011 21.8 0.0 0.83 9.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG17217.1 - 0.0035 17.3 0.0 6.3 7.2 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.24 EGG17217.1 - 0.0052 16.7 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.6 EGG17217.1 - 0.11 12.6 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGG17217.1 - 0.12 12.8 0.1 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG17217.1 - 0.14 12.5 0.0 0.4 11.0 0.0 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat Palm_thioest PF02089.15 EGG17218.1 - 5.4e-62 209.8 0.1 6.4e-62 209.5 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EGG17218.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EGG17218.1 - 0.0071 15.6 0.0 0.021 14.1 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG17218.1 - 0.032 13.9 0.5 0.06 13.0 0.5 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold aGPT-Pplase3 PF18746.1 EGG17218.1 - 1.2 8.4 4.8 2.9 7.1 0.1 2.1 2 0 0 2 2 2 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 Cupin_8 PF13621.6 EGG17219.1 - 2.5e-09 37.3 0.0 2.5e-09 37.3 0.0 5.4 2 2 1 3 3 3 1 Cupin-like domain DNA_pol_B_palm PF14792.6 EGG17220.1 - 5.8e-28 97.4 0.1 1.2e-27 96.4 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EGG17220.1 - 7.6e-22 77.3 0.1 1.5e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EGG17220.1 - 1.4e-14 53.6 0.0 4.2e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EGG17220.1 - 1.5e-12 47.7 0.1 7.7e-12 45.4 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain PTEN_C2 PF10409.9 EGG17220.1 - 5.2e-07 29.5 0.1 1.4e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein BRCT_2 PF16589.5 EGG17220.1 - 4.6e-06 26.9 0.9 6.5e-05 23.3 0.6 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG17220.1 - 0.0088 16.4 0.3 0.028 14.8 0.3 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.6 EGG17220.1 - 0.0089 16.6 0.1 0.02 15.5 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain RT_RNaseH PF17917.1 EGG17221.1 - 1.1e-27 96.3 0.0 2.6e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EGG17221.1 - 4.8e-25 87.5 0.0 1.1e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EGG17221.1 - 3.4e-15 56.2 0.1 1e-14 54.6 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EGG17221.1 - 2.5e-12 47.0 0.0 6.7e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 EGG17221.1 - 0.0016 19.1 0.0 0.0055 17.3 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease Big_8 PF17961.1 EGG17221.1 - 0.014 15.6 0.1 0.13 12.4 0.0 2.7 2 0 0 2 2 2 0 Bacterial Ig domain gag-asp_proteas PF13975.6 EGG17221.1 - 0.061 13.9 0.0 0.26 11.9 0.0 2.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RAI1 PF08652.11 EGG17223.1 - 7.1e-22 77.4 1.8 7.1e-22 77.4 1.8 2.6 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease TMEM237 PF15383.6 EGG17223.1 - 0.17 11.0 0.1 0.17 11.0 0.1 1.9 2 0 0 2 2 2 0 Transmembrane protein 237 Tim54 PF11711.8 EGG17223.1 - 0.92 8.2 11.4 0.23 10.2 1.2 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RPA43_OB PF17875.1 EGG17223.1 - 3 8.5 8.1 1.5 9.4 0.4 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF702 PF05142.12 EGG17223.1 - 3.7 8.0 6.7 2.6 8.5 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF702) RNA_pol_Rpb4 PF03874.16 EGG17223.1 - 4 7.8 15.9 4.8 7.5 2.5 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 CLN3 PF02487.17 EGG17223.1 - 5.8 5.8 8.6 1.7 7.6 0.4 2.1 2 0 0 2 2 2 0 CLN3 protein FAM176 PF14851.6 EGG17223.1 - 6.1 6.5 12.2 1.4 8.6 2.9 2.2 2 0 0 2 2 2 0 FAM176 family Ank_2 PF12796.7 EGG17224.1 - 0.0044 17.6 0.1 0.15 12.7 0.0 2.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17224.1 - 0.017 15.7 0.2 0.059 14.0 0.1 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DnaB_2 PF07261.11 EGG17224.1 - 0.042 13.6 0.1 0.48 10.2 0.0 2.2 2 0 0 2 2 2 0 Replication initiation and membrane attachment DUF3447 PF11929.8 EGG17224.1 - 0.05 13.6 6.2 0.42 10.6 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) SUIM_assoc PF16619.5 EGG17225.1 - 0.9 9.6 9.6 0.034 14.2 3.2 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ank_2 PF12796.7 EGG17226.1 - 1.6e-07 31.8 0.2 0.0098 16.5 0.0 4.8 3 1 1 5 5 5 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17226.1 - 4.5e-05 23.9 0.1 0.0032 18.0 0.0 3.8 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17226.1 - 0.0026 18.1 0.1 4.4 8.2 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat PBP1_TM PF14812.6 EGG17226.1 - 0.037 14.4 1.8 0.11 12.9 1.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_5 PF13857.6 EGG17226.1 - 0.039 14.3 0.0 7 7.1 0.0 3.8 4 1 1 5 5 5 0 Ankyrin repeats (many copies) DUF4611 PF15387.6 EGG17226.1 - 6.6 7.0 12.2 29 4.9 10.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 EGG17226.1 - 7 5.9 12.3 6.1 6.1 10.8 1.6 2 0 0 2 2 2 0 NOA36 protein Ank_2 PF12796.7 EGG17227.1 - 7.2e-09 36.1 2.6 0.0042 17.6 0.1 5.4 4 2 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17227.1 - 6.4e-06 26.6 1.0 0.048 14.3 0.3 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG17227.1 - 0.00024 21.3 0.1 40 4.7 0.0 5.3 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17227.1 - 0.02 15.4 5.3 35 5.4 0.0 6.0 6 0 0 6 6 6 0 Ankyrin repeat TMEM151 PF14857.6 EGG17228.1 - 3.8e-07 29.4 1.9 4.5e-07 29.2 1.9 1.0 1 0 0 1 1 1 1 TMEM151 family Clat_adaptor_s PF01217.20 EGG17228.1 - 0.076 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain DUF1659 PF07872.11 EGG17228.1 - 0.18 11.5 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) Ank_2 PF12796.7 EGG17229.1 - 2.6e-36 124.1 9.2 4.6e-08 33.6 0.1 6.2 1 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17229.1 - 6.1e-31 106.4 8.8 3e-05 24.5 0.4 8.7 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG17229.1 - 4.7e-29 100.1 11.0 0.0024 18.1 0.2 11.5 2 1 9 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17229.1 - 3.7e-21 73.0 3.3 0.73 10.6 0.0 12.4 12 1 1 13 13 13 4 Ankyrin repeat DUF5049 PF16468.5 EGG17229.1 - 1.1e-12 47.6 7.3 5.5 7.0 0.0 9.9 3 2 7 10 10 10 4 Domain of unknown function (DUF5049) Ank PF00023.30 EGG17229.1 - 4.1e-08 33.3 1.3 24 5.6 0.0 9.6 3 3 2 5 5 5 1 Ankyrin repeat Tom37 PF10568.9 EGG17229.1 - 0.082 13.2 1.3 42 4.5 0.8 4.5 1 1 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Abhydrolase_1 PF00561.20 EGG17230.1 - 9.2e-07 28.8 0.2 2.1e-06 27.6 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG17230.1 - 0.0053 17.4 0.0 0.0067 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG17230.1 - 0.05 12.9 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 BNR_assoc_N PF14873.6 EGG17230.1 - 0.059 13.1 0.1 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of BNR-repeat neuraminidase Pilin_GH PF16734.5 EGG17230.1 - 0.062 13.6 1.4 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Type IV pilin-like G and H, putative Phosphodiest PF01663.22 EGG17231.1 - 5.5e-09 36.1 0.3 1e-08 35.2 0.3 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EGG17231.1 - 0.0027 17.1 0.1 0.0057 16.1 0.1 1.6 1 0 0 1 1 1 1 Metalloenzyme superfamily DPM3 PF08285.11 EGG17231.1 - 0.23 11.7 0.0 0.23 11.7 0.0 3.4 3 1 1 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) RXLR PF16810.5 EGG17232.1 - 0.037 14.5 0.4 0.04 14.4 0.4 1.1 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity GRP PF07172.11 EGG17232.1 - 0.046 14.4 0.3 0.046 14.4 0.3 1.1 1 0 0 1 1 1 0 Glycine rich protein family Caleosin PF05042.13 EGG17233.1 - 0.065 13.2 0.0 0.069 13.1 0.0 1.0 1 0 0 1 1 1 0 Caleosin related protein GRP PF07172.11 EGG17233.1 - 0.13 13.0 0.0 0.14 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycine rich protein family CTU2 PF10288.9 EGG17234.1 - 7.5 6.8 7.4 0.21 11.9 1.1 1.6 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Rhomboid PF01694.22 EGG17235.1 - 9.2e-22 77.7 9.8 9.2e-22 77.7 9.8 1.5 2 0 0 2 2 2 1 Rhomboid family MORN PF02493.20 EGG17235.1 - 0.013 15.3 0.4 0.2 11.6 0.1 2.6 2 0 0 2 2 2 0 MORN repeat DUF1924 PF09086.11 EGG17235.1 - 0.27 11.6 4.2 0.22 11.9 2.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1924) Band_3_cyto PF07565.13 EGG17235.1 - 1.2 8.9 3.2 1.8 8.3 3.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Kinesin_assoc PF16183.5 EGG17235.1 - 4.4 7.4 9.3 1 9.5 1.5 2.1 1 1 1 2 2 2 0 Kinesin-associated Ank_2 PF12796.7 EGG17236.1 - 3.1e-27 95.0 13.6 5.3e-07 30.1 0.0 6.5 3 3 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17236.1 - 7.3e-24 83.8 9.9 0.0014 19.1 0.0 9.5 6 3 2 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG17236.1 - 1.2e-20 73.3 7.3 0.0044 17.3 0.0 10.4 5 4 6 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17236.1 - 1e-11 43.9 5.1 6.2 7.7 0.0 11.3 12 1 1 13 13 13 2 Ankyrin repeat DUF5049 PF16468.5 EGG17236.1 - 0.0045 16.9 0.0 11 6.0 0.0 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF5049) Ank PF00023.30 EGG17236.1 - 0.28 11.7 7.2 55 4.5 0.2 7.0 6 3 0 6 6 6 0 Ankyrin repeat WD40 PF00400.32 EGG17237.1 - 7.6e-12 45.6 8.7 0.002 18.9 0.1 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG17237.1 - 4.1e-10 39.8 2.9 0.0013 19.0 0.7 5.0 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG17237.1 - 0.003 16.3 0.1 0.013 14.2 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EGG17237.1 - 0.018 15.5 0.2 0.57 10.7 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain Choline_kinase PF01633.20 EGG17238.1 - 1.5e-59 201.1 0.6 1.5e-59 201.1 0.6 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EGG17238.1 - 7.4e-07 29.3 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGG17238.1 - 6.1e-05 22.5 1.5 6.1e-05 22.5 1.5 2.0 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 EGG17238.1 - 0.0079 15.1 2.1 0.014 14.3 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) EGF_2 PF07974.13 EGG17239.1 - 0.00027 21.3 14.4 0.00058 20.2 14.4 1.6 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG17239.1 - 0.00088 19.3 5.8 0.002 18.1 5.8 1.6 1 0 0 1 1 1 1 Tenascin EGF domain hEGF PF12661.7 EGG17239.1 - 0.0011 19.6 9.7 0.0028 18.2 9.7 1.8 1 0 0 1 1 1 1 Human growth factor-like EGF EGF PF00008.27 EGG17239.1 - 0.0024 18.2 10.2 0.0069 16.7 10.2 1.9 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 EGG17239.1 - 0.0094 16.2 3.1 0.024 14.9 3.1 1.6 1 0 0 1 1 1 1 EB module I-EGF_1 PF18372.1 EGG17239.1 - 0.07 13.2 7.6 0.16 12.1 7.6 1.6 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 DUF3844 PF12955.7 EGG17239.1 - 0.089 12.9 4.7 0.22 11.7 3.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) EGF_CA PF07645.15 EGG17239.1 - 7.7 6.8 15.6 1.3 9.3 11.5 1.9 2 0 0 2 2 2 0 Calcium-binding EGF domain PDEase_I PF00233.19 EGG17240.1 - 0.0047 16.7 2.5 0.0047 16.7 2.5 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase V-ATPase_H_C PF11698.8 EGG17240.1 - 0.016 15.3 0.5 0.53 10.4 0.0 2.9 3 0 0 3 3 3 0 V-ATPase subunit H PMC2NT PF08066.12 EGG17241.1 - 2e-21 76.5 0.3 2e-21 76.5 0.3 4.3 5 1 1 6 6 6 1 PMC2NT (NUC016) domain DUF3439 PF11921.8 EGG17241.1 - 4.8 7.2 36.6 0.038 14.0 1.1 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF3439) PHD PF00628.29 EGG17242.1 - 1.3e-05 25.0 19.1 0.0004 20.2 9.6 3.7 2 1 1 3 3 3 2 PHD-finger DUF282 PF03380.14 EGG17242.1 - 0.77 9.7 4.4 0.21 11.6 0.6 2.0 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 PHD_2 PF13831.6 EGG17242.1 - 2.7 7.6 15.9 0.37 10.4 8.1 3.2 2 1 1 3 3 3 0 PHD-finger Zf_RING PF16744.5 EGG17242.1 - 4.9 7.3 8.4 0.23 11.6 1.7 2.3 2 0 0 2 2 2 0 KIAA1045 RING finger TRAM_LAG1_CLN8 PF03798.16 EGG17244.1 - 1.8e-37 129.0 29.7 1.8e-37 129.0 29.7 2.0 2 0 0 2 2 2 2 TLC domain Peptidase_M48 PF01435.18 EGG17245.1 - 1.1e-24 87.3 0.0 2.7e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 EGG17245.1 - 2e-14 53.9 5.7 2.4e-08 34.1 0.1 3.8 4 0 0 4 4 4 2 CAAX prenyl protease N-terminal, five membrane helices DDHD PF02862.17 EGG17245.1 - 7.4e-05 23.0 2.0 0.008 16.4 0.0 2.2 2 0 0 2 2 2 1 DDHD domain Connexin PF00029.19 EGG17245.1 - 0.00019 21.3 13.4 0.00024 20.9 3.9 2.6 2 1 0 2 2 2 1 Connexin DUF4199 PF13858.6 EGG17245.1 - 0.0002 21.8 0.0 0.0002 21.8 0.0 3.7 4 1 0 4 4 2 1 Protein of unknown function (DUF4199) CLN3 PF02487.17 EGG17245.1 - 0.0013 17.9 4.4 0.023 13.8 0.2 2.4 2 0 0 2 2 2 1 CLN3 protein CSG2 PF16965.5 EGG17245.1 - 0.0033 16.5 0.2 0.0033 16.5 0.2 2.9 3 0 0 3 3 3 1 Ceramide synthase regulator AAR2 PF05282.11 EGG17245.1 - 0.0038 16.7 3.3 0.52 9.7 0.0 2.2 2 0 0 2 2 2 2 AAR2 protein Peroxin-13_N PF04088.13 EGG17245.1 - 0.0042 17.4 2.2 0.25 11.6 0.1 2.6 2 0 0 2 2 2 1 Peroxin 13, N-terminal region Peptidase_M56 PF05569.11 EGG17245.1 - 0.0058 15.9 1.3 0.0058 15.9 1.3 3.8 4 1 0 4 4 3 1 BlaR1 peptidase M56 EMC3_TMCO1 PF01956.16 EGG17245.1 - 0.0069 16.1 1.3 0.0069 16.1 1.3 3.0 3 0 0 3 3 2 1 Integral membrane protein EMC3/TMCO1-like DUF4834 PF16118.5 EGG17245.1 - 0.0072 17.3 4.1 0.0072 17.3 4.1 3.1 3 0 0 3 3 2 1 Domain of unknown function (DUF4834) DUF3464 PF11947.8 EGG17245.1 - 0.0079 16.0 0.1 0.0079 16.0 0.1 2.4 2 0 0 2 2 2 1 Photosynthesis affected mutant 68 Eapp_C PF10238.9 EGG17245.1 - 0.021 14.9 2.0 0.021 14.9 2.0 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein UPF0565 PF10561.9 EGG17245.1 - 0.024 13.8 0.1 0.024 13.8 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0565 SnAPC_2_like PF11035.8 EGG17245.1 - 0.031 14.4 0.8 0.031 14.4 0.8 2.0 2 0 0 2 2 2 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF5308 PF17233.2 EGG17245.1 - 0.041 14.1 0.9 1.6 9.0 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5308) DUF3043 PF11241.8 EGG17245.1 - 0.044 13.8 0.3 0.18 11.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Ctr PF04145.15 EGG17245.1 - 0.046 14.3 4.6 0.19 12.3 0.0 2.9 2 0 0 2 2 2 0 Ctr copper transporter family DUF4337 PF14235.6 EGG17245.1 - 0.049 13.8 0.4 0.049 13.8 0.4 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4337) Ureide_permease PF07168.11 EGG17245.1 - 0.05 12.4 0.1 0.05 12.4 0.1 2.9 3 0 0 3 3 2 0 Ureide permease DCX PF03607.17 EGG17245.1 - 0.054 13.6 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Doublecortin DUF4228 PF14009.6 EGG17245.1 - 0.059 13.8 0.4 1.2 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) HXXEE PF13787.6 EGG17245.1 - 0.066 14.0 6.2 7.1 7.5 1.3 3.1 3 0 0 3 3 3 0 Protein of unknown function with HXXEE motif FHIPEP PF00771.20 EGG17245.1 - 0.068 11.6 0.1 0.14 10.6 0.1 1.5 1 0 0 1 1 1 0 FHIPEP family CPSF100_C PF13299.6 EGG17245.1 - 0.091 12.9 14.4 0.041 14.1 3.3 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 EGG17245.1 - 0.23 10.6 0.0 0.23 10.6 0.0 2.7 3 0 0 3 3 2 0 ZIP Zinc transporter SpoIIP PF07454.11 EGG17245.1 - 0.59 9.5 22.5 0.17 11.3 8.4 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) PEX11 PF05648.14 EGG17245.1 - 1.3 8.4 7.6 0.21 11.0 1.2 2.3 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) SLC12 PF03522.15 EGG17245.1 - 1.3 8.0 15.2 0.36 9.8 4.0 2.1 2 0 0 2 2 2 0 Solute carrier family 12 TRAP_alpha PF03896.16 EGG17245.1 - 1.5 8.0 12.3 0.049 12.8 3.1 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Neur_chan_memb PF02932.16 EGG17245.1 - 1.6 8.8 5.1 2.7 8.0 0.6 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RNA_pol_Rpc4 PF05132.14 EGG17245.1 - 2 8.8 15.0 0.064 13.7 2.9 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF2828 PF11443.8 EGG17245.1 - 2.3 6.2 13.0 0.037 12.1 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DUF4518 PF15008.6 EGG17245.1 - 2.3 7.3 14.8 0.2 10.8 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) OATP PF03137.20 EGG17245.1 - 2.4 6.3 7.9 0.14 10.5 0.2 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family YlaC PF10777.9 EGG17245.1 - 2.6 7.9 9.4 0.18 11.6 0.2 3.1 3 0 0 3 3 3 0 Inner membrane protein YlaC DUF913 PF06025.12 EGG17245.1 - 2.7 6.9 9.3 0.091 11.7 0.8 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) ASC PF00858.24 EGG17245.1 - 3.3 6.6 12.7 0.26 10.2 0.1 2.4 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel RPOL_N PF14700.6 EGG17245.1 - 4 6.8 15.4 0.027 13.9 1.6 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal AAA_11 PF13086.6 EGG17245.1 - 4.2 7.1 14.1 1.8 8.3 5.5 2.1 2 0 0 2 2 2 0 AAA domain Apis_Csd PF11671.8 EGG17245.1 - 4.9 7.1 21.9 5.6 7.0 0.4 2.3 2 0 0 2 2 2 0 Complementary sex determiner protein MID_MedPIWI PF18296.1 EGG17245.1 - 5.5 6.7 10.6 6.3 6.5 0.5 2.2 2 0 0 2 2 2 0 MID domain of medPIWI BSP_II PF05432.11 EGG17245.1 - 6.3 6.4 33.5 2.7 7.6 16.7 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Band_3_cyto PF07565.13 EGG17245.1 - 6.4 6.5 11.4 0.64 9.8 2.7 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FAM176 PF14851.6 EGG17245.1 - 7.3 6.2 20.1 0.047 13.4 7.0 2.4 2 0 0 2 2 2 0 FAM176 family CSRNP_N PF16019.5 EGG17245.1 - 8.9 6.2 15.7 0.15 11.9 3.3 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Folliculin PF11704.8 EGG17245.1 - 8.9 6.1 13.5 0.3 10.9 2.1 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport LRRC37AB_C PF14914.6 EGG17245.1 - 9.1 6.2 19.9 0.11 12.4 4.9 2.3 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain PDEase_I PF00233.19 EGG17246.1 - 3.2e-86 288.9 1.2 3.2e-86 288.9 1.2 2.8 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 EGG17246.1 - 5.2e-25 87.8 0.5 1.5e-24 86.3 0.5 1.8 1 0 0 1 1 1 1 Response regulator receiver domain FliG_N PF14842.6 EGG17246.1 - 0.088 13.4 5.2 0.076 13.6 1.8 2.6 3 0 0 3 3 3 0 FliG N-terminal domain Pep_deformylase PF01327.21 EGG17247.1 - 1.4e-29 102.8 0.0 8.3e-29 100.2 0.0 1.9 1 1 0 1 1 1 1 Polypeptide deformylase DDE_1 PF03184.19 EGG17249.1 - 4.4e-11 42.7 2.3 5.1e-11 42.5 0.9 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EGG17249.1 - 3.5e-06 26.9 0.8 8.7e-06 25.7 0.8 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain RNA_pol_Rpb5_C PF01191.19 EGG17249.1 - 0.0097 15.8 1.5 0.013 15.4 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain DUF2603 PF10788.9 EGG17249.1 - 0.03 14.3 1.6 0.08 13.0 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) BAR PF03114.18 EGG17250.1 - 3.2e-05 23.7 2.5 5.6e-05 22.9 2.5 1.4 1 0 0 1 1 1 1 BAR domain DnaJ PF00226.31 EGG17250.1 - 0.0012 18.9 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain YscO-like PF16789.5 EGG17250.1 - 0.87 9.6 5.5 0.26 11.3 1.4 2.1 2 0 0 2 2 2 0 YscO-like protein RsgA_GTPase PF03193.16 EGG17251.1 - 6.8e-05 22.8 0.8 0.00016 21.6 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EGG17251.1 - 0.00023 21.2 0.3 0.0031 17.6 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGG17251.1 - 0.0024 18.4 1.8 0.0081 16.7 0.0 2.6 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.6 EGG17251.1 - 0.0056 16.8 0.0 0.041 14.0 0.0 2.4 2 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EGG17251.1 - 0.0098 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1033 PF06279.11 EGG17251.1 - 0.035 14.3 1.1 0.035 14.3 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1033) AAA_22 PF13401.6 EGG17251.1 - 0.041 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGG17251.1 - 0.077 12.6 0.1 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 EGG17251.1 - 0.079 12.7 0.0 0.079 12.7 0.0 2.5 2 1 0 2 2 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGG17251.1 - 0.14 12.6 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SlyX PF04102.12 EGG17251.1 - 0.38 11.4 5.9 1 10.0 5.9 1.7 1 0 0 1 1 1 0 SlyX AAA_18 PF13238.6 EGG17251.1 - 1.1 9.9 0.0 1.1 9.9 0.0 3.3 3 1 1 4 4 3 0 AAA domain Sigma54_activat PF00158.26 EGG17252.1 - 0.059 13.1 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.9 EGG17252.1 - 0.068 12.1 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RHSP PF07999.11 EGG17252.1 - 0.081 11.7 0.1 3 6.5 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon hot spot protein AAA_5 PF07728.14 EGG17252.1 - 0.16 11.9 0.0 0.3 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EGG17252.1 - 0.17 11.8 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Nop14 PF04147.12 EGG17253.1 - 0.054 11.7 46.6 0.24 9.6 24.5 2.2 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 EGG17253.1 - 0.25 9.6 29.7 0.69 8.1 12.5 2.4 2 0 0 2 2 2 0 CDC45-like protein FNIP PF05725.12 EGG17253.1 - 1.2 9.4 23.4 0.26 11.5 0.1 5.9 6 1 1 7 7 7 0 FNIP Repeat Prothymosin PF03247.14 EGG17253.1 - 4.4 7.8 63.2 3.5 8.1 0.1 4.1 3 0 0 3 3 3 0 Prothymosin/parathymosin family FNIP PF05725.12 EGG17254.1 - 0.0016 18.6 28.1 0.58 10.4 0.5 8.6 7 2 2 9 9 9 4 FNIP Repeat Sporozoite_P67 PF05642.11 EGG17254.1 - 0.076 11.1 1.3 0.12 10.5 1.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.12 EGG17254.1 - 1.5 8.1 10.5 2.3 7.5 10.5 1.2 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 EGG17254.1 - 2.5 7.7 6.4 4.9 6.8 6.4 1.4 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 EGG17254.1 - 3.5 5.7 11.6 5.5 5.1 11.6 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EGG17254.1 - 3.5 6.9 8.5 5.2 6.3 8.5 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 EGG17254.1 - 3.5 5.6 14.9 5.5 5.0 14.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi IP_trans PF02121.18 EGG17258.1 - 1.5e-109 365.3 0.1 3.3e-109 364.2 0.0 1.6 2 0 0 2 2 1 1 Phosphatidylinositol transfer protein zf-RING_2 PF13639.6 EGG17258.1 - 1.3e-13 51.0 9.2 4e-13 49.5 9.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG17258.1 - 3.9e-09 36.2 8.6 8.1e-09 35.2 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG17258.1 - 2.8e-08 33.5 9.5 2.8e-08 33.5 9.5 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGG17258.1 - 4.4e-08 32.7 8.6 4.4e-08 32.7 8.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGG17258.1 - 3.1e-07 30.3 3.5 3.1e-07 30.3 3.5 2.7 2 1 1 3 3 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGG17258.1 - 9.7e-07 29.0 10.1 4.6e-06 26.8 10.1 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGG17258.1 - 1.4e-05 25.0 6.7 2.8e-05 24.0 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGG17258.1 - 9e-05 22.3 4.8 0.00019 21.2 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PRIMA1 PF16101.5 EGG17258.1 - 0.00088 19.3 6.9 0.002 18.1 6.9 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 UL42 PF17638.2 EGG17258.1 - 0.0011 19.0 0.5 0.0021 18.0 0.5 1.4 1 0 0 1 1 1 1 HCMV UL42 zf-ANAPC11 PF12861.7 EGG17258.1 - 0.0031 17.5 2.2 0.009 16.0 2.2 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PcfK PF14058.6 EGG17258.1 - 0.0078 16.5 1.1 0.018 15.3 1.1 1.5 1 0 0 1 1 1 1 PcfK-like protein SPX PF03105.19 EGG17258.1 - 0.011 15.7 3.6 0.014 15.3 3.6 1.2 1 0 0 1 1 1 0 SPX domain Mito_fiss_reg PF05308.11 EGG17258.1 - 0.028 14.5 10.9 0.049 13.7 10.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EGG17258.1 - 0.031 13.8 8.2 0.05 13.1 8.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PhoR PF11808.8 EGG17258.1 - 0.067 13.6 0.6 0.13 12.7 0.6 1.4 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR GAGA PF09237.11 EGG17258.1 - 0.12 12.2 0.9 3.5 7.5 0.1 2.9 2 0 0 2 2 2 0 GAGA factor CPSase_L_D3 PF02787.19 EGG17258.1 - 0.12 12.7 0.4 0.24 11.7 0.4 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Lin-8 PF03353.15 EGG17258.1 - 0.15 11.6 5.2 0.32 10.5 5.2 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Prok-RING_4 PF14447.6 EGG17258.1 - 0.18 11.7 9.3 0.7 9.8 8.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 EGG17258.1 - 0.2 11.8 8.8 0.61 10.3 8.8 1.9 1 0 0 1 1 1 0 RING-variant domain Macoilin PF09726.9 EGG17258.1 - 1 7.9 7.5 1.6 7.2 7.5 1.2 1 0 0 1 1 1 0 Macoilin family zf-RING_10 PF16685.5 EGG17258.1 - 4.8 7.4 8.4 1.3 9.2 4.4 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 Menin PF05053.13 EGG17258.1 - 8.5 4.6 7.4 16 3.7 7.4 1.3 1 0 0 1 1 1 0 Menin Peptidase_M24 PF00557.24 EGG17259.1 - 4e-21 75.7 0.0 5.2e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 EFP_N PF08207.12 EGG17260.1 - 7.5e-12 45.1 0.4 1.4e-11 44.2 0.4 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Peptidase_C54 PF03416.19 EGG17261.1 - 1.7e-92 309.7 0.7 3.2e-92 308.8 0.7 1.4 1 0 0 1 1 1 1 Peptidase family C54 zf-HIT PF04438.16 EGG17262.1 - 0.0032 17.3 4.8 0.0054 16.6 4.8 1.3 1 0 0 1 1 1 1 HIT zinc finger Mucin PF01456.17 EGG17268.1 - 0.043 13.8 50.4 0.11 12.5 23.5 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein RRM_1 PF00076.22 EGG17268.1 - 0.11 12.3 0.1 0.41 10.5 0.1 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dendrin PF15498.6 EGG17268.1 - 0.17 10.6 1.5 0.82 8.3 0.0 2.0 2 0 0 2 2 2 0 Nephrin and CD2AP-binding protein, Dendrin zf-C2HCIx2C PF10782.9 EGG17268.1 - 0.32 11.0 3.9 0.55 10.2 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger Ecl1 PF12855.7 EGG17268.1 - 0.6 11.3 17.5 1.1 10.4 9.3 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Sporozoite_P67 PF05642.11 EGG17268.1 - 1.2 7.2 18.1 0.68 7.9 1.2 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen MGC-24 PF05283.11 EGG17268.1 - 2.1 8.8 22.8 2.3 8.7 3.2 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin NUDE_C PF04880.13 EGG17268.1 - 2.9 8.3 15.8 0.64 10.5 7.7 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Med3 PF11593.8 EGG17268.1 - 9.7 5.3 19.2 0.28 10.3 2.4 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Pro-kuma_activ PF09286.11 EGG17271.1 - 4.9e-31 107.9 0.0 7e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain SR-25 PF10500.9 EGG17272.1 - 0.0023 17.6 7.8 0.0023 17.6 7.8 1.8 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Aldedh PF00171.22 EGG17273.1 - 3.3e-160 533.6 0.0 3.8e-160 533.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4863 PF16155.5 EGG17273.1 - 0.11 12.4 0.1 11 5.9 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4863) SecY PF00344.20 EGG17274.1 - 1.7e-75 254.1 12.5 2.1e-75 253.8 12.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EGG17274.1 - 6e-18 64.4 1.6 1e-17 63.6 0.1 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p DUF1430 PF07242.11 EGG17274.1 - 5.8 7.2 8.7 4.3 7.6 1.5 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1430) Presenilin PF01080.17 EGG17275.1 - 4.2 6.0 7.3 5 5.8 7.3 1.1 1 0 0 1 1 1 0 Presenilin CBS PF00571.28 EGG17276.1 - 1.4e-14 54.3 0.9 0.00033 21.0 0.1 3.8 4 0 0 4 4 4 3 CBS domain DUF1848 PF08902.11 EGG17277.1 - 0.69 9.6 7.6 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) GREB1 PF15782.5 EGG17277.1 - 2 5.4 23.6 2.4 5.1 23.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HOOK PF05622.12 EGG17277.1 - 2.2 6.3 38.4 4.7 5.2 38.4 1.5 1 1 0 1 1 1 0 HOOK protein DUF3767 PF12597.8 EGG17280.1 - 5.5e-11 42.2 0.0 7e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) ADH_N PF08240.12 EGG17281.1 - 1.7e-08 34.3 0.0 3.7e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGG17281.1 - 2.9e-06 28.3 0.0 4.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGG17281.1 - 1.8e-05 24.7 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 EGG17281.1 - 0.022 15.2 0.0 0.037 14.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GRIP PF01465.20 EGG17282.1 - 3.5e-11 42.8 0.0 1.1e-10 41.2 0.0 2.0 1 0 0 1 1 1 1 GRIP domain AcetDehyd-dimer PF09290.11 EGG17282.1 - 0.13 12.5 3.2 18 5.5 0.1 3.6 3 0 0 3 3 3 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation P5CR_dimer PF14748.6 EGG17283.1 - 3.1e-26 91.6 1.0 5.7e-26 90.8 1.0 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EGG17283.1 - 0.00032 21.2 0.1 0.0021 18.6 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EGG17283.1 - 0.0047 17.2 0.1 0.011 16.0 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Pkinase_Tyr PF07714.17 EGG17284.1 - 1.7e-48 165.2 0.0 2.1e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG17284.1 - 7.8e-42 143.5 0.0 5.9e-41 140.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Med13_C PF06333.12 EGG17284.1 - 0.0049 16.2 1.9 0.0049 16.2 1.9 2.0 1 1 1 2 2 2 1 Mediator complex subunit 13 C-terminal domain Haspin_kinase PF12330.8 EGG17284.1 - 0.052 12.5 0.6 0.3 10.0 0.0 2.2 2 1 0 2 2 2 0 Haspin like kinase domain WD40 PF00400.32 EGG17286.1 - 5.7e-10 39.6 0.6 0.00027 21.7 0.0 4.2 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG17286.1 - 1.6e-07 31.6 0.1 0.026 14.8 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 EGG17286.1 - 0.0013 18.1 0.1 0.0033 16.7 0.1 1.7 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PQQ_2 PF13360.6 EGG17286.1 - 0.0059 16.2 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain PD40 PF07676.12 EGG17286.1 - 0.012 15.5 0.0 0.072 13.0 0.0 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SGL PF08450.12 EGG17286.1 - 0.019 14.5 0.0 0.47 10.0 0.0 2.9 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 EGG17286.1 - 0.033 14.7 0.4 2.7 8.6 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain SPASM PF13186.6 EGG17286.1 - 0.035 14.6 0.2 0.3 11.6 0.0 2.5 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain Reg_prop PF07494.11 EGG17286.1 - 0.039 14.2 0.0 39 5.0 0.0 4.2 4 0 0 4 4 4 0 Two component regulator propeller SLC12 PF03522.15 EGG17286.1 - 0.96 8.4 20.2 1.4 7.9 20.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Branch PF02485.21 EGG17287.1 - 3.2e-14 53.0 3.3 2.2e-13 50.3 3.3 2.0 1 1 0 1 1 1 1 Core-2/I-Branching enzyme SWIM PF04434.17 EGG17287.1 - 0.14 11.9 1.0 0.35 10.6 1.0 1.7 1 0 0 1 1 1 0 SWIM zinc finger MTCP1 PF08991.10 EGG17287.1 - 2.9 8.2 8.0 6 7.2 8.0 1.5 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Cupin_8 PF13621.6 EGG17288.1 - 1.8e-42 145.8 1.6 1.8e-42 145.8 1.6 2.0 2 1 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 EGG17288.1 - 6.8e-11 42.2 0.1 8.3e-10 38.6 0.1 2.3 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EGG17288.1 - 0.00013 22.3 1.3 0.00019 21.8 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EGG17288.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Eaf7 PF07904.13 EGG17288.1 - 0.91 9.9 4.6 1.6 9.1 0.1 3.1 2 1 0 2 2 2 0 Chromatin modification-related protein EAF7 Cystatin PF00031.21 EGG17291.1 - 3.8e-10 39.9 0.0 7.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Cystatin domain SDA1 PF05285.12 EGG17292.1 - 0.072 12.5 12.5 0.091 12.2 12.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EGG17292.1 - 0.75 8.0 8.2 0.97 7.6 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EGG17292.1 - 1.7 7.9 18.0 2.4 7.4 18.0 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EGG17292.1 - 5.1 5.2 13.3 6.6 4.8 13.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1741 PF08427.10 EGG17293.1 - 7.6e-59 199.2 3.0 7.6e-59 199.2 3.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1741) G-alpha PF00503.20 EGG17294.1 - 8.1e-116 387.0 4.6 8.1e-116 387.0 4.6 3.2 2 1 0 2 2 2 1 G-protein alpha subunit Arf PF00025.21 EGG17294.1 - 6.8e-12 45.2 4.0 1.4e-08 34.4 0.1 3.3 3 0 0 3 3 3 2 ADP-ribosylation factor family ArgJ PF01960.18 EGG17297.1 - 7.8e-142 472.4 13.1 8.9e-142 472.3 13.1 1.0 1 0 0 1 1 1 1 ArgJ family Ank_2 PF12796.7 EGG17298.1 - 1e-55 186.2 8.2 9.1e-14 51.8 0.1 7.0 4 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17298.1 - 1.1e-44 150.2 5.9 3.7e-07 30.6 0.0 8.2 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG17298.1 - 2.4e-43 145.6 8.5 2.6e-10 40.3 0.0 8.8 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17298.1 - 1.8e-38 126.1 12.4 5.4e-05 23.3 0.0 11.3 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 EGG17298.1 - 2.6e-38 128.8 5.5 0.00019 21.7 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat MATH PF00917.26 EGG17298.1 - 5.1e-23 81.4 17.8 7.7e-13 48.6 0.4 4.4 4 0 0 4 4 4 3 MATH domain BTB PF00651.31 EGG17298.1 - 2.1e-22 79.5 0.8 9e-22 77.4 0.4 2.4 2 0 0 2 2 2 1 BTB/POZ domain Med22 PF06179.12 EGG17298.1 - 3.1e-20 72.4 8.6 3.1e-20 72.4 8.6 2.5 2 0 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex MAPKK1_Int PF08923.10 EGG17298.1 - 0.33 10.8 2.9 0.34 10.7 0.6 2.3 3 0 0 3 3 3 0 Mitogen-activated protein kinase kinase 1 interacting Pkinase PF00069.25 EGG17299.1 - 2.5e-48 164.7 0.7 6.7e-48 163.3 0.7 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG17299.1 - 4.3e-28 98.3 0.1 9.3e-28 97.2 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase ANTH PF07651.16 EGG17299.1 - 1.5e-19 70.0 0.2 8.8e-19 67.6 0.0 2.3 2 0 0 2 2 2 1 ANTH domain APH PF01636.23 EGG17299.1 - 0.092 12.7 0.0 0.092 12.7 0.0 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family DnaJ_C PF01556.18 EGG17300.1 - 3.2e-37 127.9 0.7 4.3e-37 127.5 0.7 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGG17300.1 - 5.8e-27 93.6 2.3 9.5e-27 92.9 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGG17300.1 - 6.6e-14 52.0 19.0 1.4e-13 51.0 19.0 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGG17300.1 - 5e-07 29.6 16.3 0.0005 20.0 5.1 2.6 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGG17300.1 - 0.0036 17.3 9.8 0.23 11.5 2.9 2.3 1 1 1 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EGG17300.1 - 0.01 15.5 6.8 0.38 10.4 1.5 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf_CopZ PF18423.1 EGG17300.1 - 0.068 13.1 7.2 0.39 10.7 0.8 3.2 2 1 1 3 3 3 0 Zinc binding domain DZR PF12773.7 EGG17300.1 - 1.8 8.7 12.6 1.1e+02 3.0 1.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 EGG17300.1 - 2.3 8.5 7.5 30 5.0 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon Cytochrom_c3_2 PF14537.6 EGG17300.1 - 3.7 8.1 10.3 8.2 7.0 3.9 2.4 1 1 2 3 3 3 0 Cytochrome c3 Cytochrom_C550 PF14495.6 EGG17300.1 - 4.6 7.0 5.6 12 5.6 4.4 2.3 1 1 1 2 2 2 0 Cytochrome c-550 domain TFIIS_C PF01096.18 EGG17300.1 - 5.6 6.9 12.2 4.9 7.1 0.2 3.9 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) Cytochrome_C7 PF14522.6 EGG17300.1 - 6.2 6.9 11.3 23 5.1 8.7 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c ADH_zinc_N PF00107.26 EGG17301.1 - 2.7e-28 98.5 0.0 6.3e-28 97.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGG17301.1 - 1e-20 75.1 0.0 3.3e-20 73.5 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG17301.1 - 4.6e-10 39.4 0.0 1.9e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 EGG17301.1 - 0.039 13.4 0.2 0.062 12.7 0.2 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme SWI2_SNF2 PF18766.1 EGG17302.1 - 7.5e-27 94.5 0.2 2.6e-26 92.7 0.2 1.9 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ResIII PF04851.15 EGG17302.1 - 1.4e-17 64.2 0.4 1.4e-17 64.2 0.4 3.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Phosphodiest PF01663.22 EGG17303.1 - 1.4e-06 28.2 0.0 7.8e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Myc_N PF01056.18 EGG17303.1 - 0.021 14.7 0.5 0.041 13.8 0.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region S4 PF01479.25 EGG17304.1 - 3.2e-05 23.5 0.0 7.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 EGG17304.1 - 0.071 14.0 1.7 0.15 13.0 0.4 2.1 2 1 0 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain PLDc PF00614.22 EGG17307.1 - 4.7e-21 74.1 1.0 6.5e-09 35.6 0.0 3.6 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGG17307.1 - 5.6e-20 71.6 0.8 2.2e-11 43.8 0.5 2.7 2 0 0 2 2 2 2 PLD-like domain SWIRM PF04433.17 EGG17309.1 - 8.7e-19 67.7 0.4 3e-18 66.0 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 EGG17309.1 - 3.3e-17 62.4 4.3 1.7e-08 34.5 0.2 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain JAB PF01398.21 EGG17309.1 - 9e-13 48.2 2.7 1.5e-12 47.6 0.0 2.7 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EGG17309.1 - 2.5e-08 33.7 0.1 8.4e-08 32.0 0.1 1.8 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.6 EGG17309.1 - 2.4e-07 30.9 7.3 0.0035 17.6 0.1 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGG17309.1 - 0.0098 15.8 1.8 0.0098 15.8 1.8 4.1 3 1 1 4 4 4 2 Myb DNA-binding like ATP_bind_1 PF03029.17 EGG17310.1 - 1.3e-77 260.9 0.0 1.6e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 EGG17310.1 - 3.7e-06 27.0 0.1 0.00089 19.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 EGG17310.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EGG17310.1 - 0.0022 18.1 0.0 0.0029 17.6 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CLP1_P PF16575.5 EGG17310.1 - 0.02 14.7 0.0 0.058 13.2 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 EGG17310.1 - 0.048 13.4 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG17310.1 - 0.07 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EGG17310.1 - 0.079 13.0 0.0 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGG17310.1 - 0.09 13.3 1.0 0.27 11.8 0.0 2.3 2 2 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGG17310.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGG17310.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.6 EGG17310.1 - 0.19 12.1 0.2 2.4 8.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain EMP24_GP25L PF01105.24 EGG17311.1 - 3.9e-48 163.8 0.1 4.9e-48 163.5 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 EGG17311.1 - 0.011 16.0 0.1 0.018 15.2 0.1 1.5 1 1 0 1 1 1 0 SdrD B-like domain NDUF_B12 PF08122.12 EGG17312.1 - 9e-07 28.9 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family DUF3238 PF11579.8 EGG17313.1 - 0.055 13.3 0.0 0.059 13.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3238) UbiA PF01040.18 EGG17314.1 - 1.2e-52 178.7 17.8 1.8e-52 178.2 17.8 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family PAS_12 PF18095.1 EGG17314.1 - 0.049 13.3 1.5 0.11 12.2 1.5 1.6 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain bZIP_1 PF00170.21 EGG17315.1 - 3e-13 49.7 2.1 8.2e-13 48.2 2.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGG17315.1 - 1.6e-11 44.1 1.5 1.6e-11 44.1 1.5 2.9 4 0 0 4 4 4 1 Basic region leucine zipper Shugoshin_N PF07558.11 EGG17315.1 - 0.00068 19.5 0.1 0.0026 17.6 0.1 2.1 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region bZIP_Maf PF03131.17 EGG17315.1 - 0.00077 19.9 3.6 0.00077 19.9 3.6 3.6 2 1 1 3 3 3 1 bZIP Maf transcription factor Herpes_BLRF2 PF05812.12 EGG17315.1 - 0.034 14.3 4.8 0.049 13.8 0.7 2.5 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein FKBP_N PF01346.18 EGG17315.1 - 9.7 7.2 22.5 0.27 12.2 3.6 3.3 3 1 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase G-patch PF01585.23 EGG17316.1 - 9.9e-12 44.6 3.3 1.8e-11 43.7 3.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGG17316.1 - 0.00021 21.3 2.6 0.00021 21.3 2.6 3.4 4 1 0 4 4 4 1 G-patch domain CAP PF00188.26 EGG17317.1 - 1.1e-13 52.1 0.1 1.7e-13 51.5 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CH PF00307.31 EGG17320.1 - 2.8e-81 268.8 4.7 2.7e-21 75.8 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_1 PF00036.32 EGG17320.1 - 5.2e-14 50.7 3.9 7.2e-07 28.3 0.6 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGG17320.1 - 1.2e-12 48.1 0.5 9.2e-12 45.2 0.3 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EGG17320.1 - 2.2e-11 43.4 2.2 1.5e-10 40.7 0.7 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGG17320.1 - 5.1e-11 41.6 0.7 3e-05 23.6 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGG17320.1 - 6.7e-10 38.0 3.6 0.00026 20.4 0.3 2.7 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 EGG17320.1 - 0.00042 20.1 0.1 1.1 9.1 0.0 3.4 3 0 0 3 3 3 2 CAMSAP CH domain SPARC_Ca_bdg PF10591.9 EGG17320.1 - 0.047 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1685 PF07939.11 EGG17320.1 - 0.14 11.9 0.0 0.78 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1685) IF4E PF01652.18 EGG17321.1 - 5.3e-37 127.1 0.1 1.1e-36 126.0 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2052 PF09747.9 EGG17321.1 - 0.34 11.0 20.4 0.077 13.1 16.7 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Kelch_6 PF13964.6 EGG17322.1 - 1.1e-17 63.6 9.1 2.1e-05 24.6 0.0 5.8 3 2 2 5 5 5 5 Kelch motif Kelch_1 PF01344.25 EGG17322.1 - 3.5e-17 61.7 15.7 0.00069 19.1 0.1 6.0 5 1 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EGG17322.1 - 1.5e-14 53.7 11.6 0.00029 20.8 0.1 5.9 3 2 2 5 5 5 3 Galactose oxidase, central domain zf-B_box PF00643.24 EGG17322.1 - 4.9e-11 42.6 5.6 4.9e-11 42.6 5.6 2.3 2 0 0 2 2 2 1 B-box zinc finger Kelch_2 PF07646.15 EGG17322.1 - 7.9e-09 35.2 6.4 0.0066 16.4 0.0 5.0 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 EGG17322.1 - 1.1e-05 25.3 9.5 0.028 14.4 0.2 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EGG17322.1 - 0.0093 16.2 6.1 4.8 7.6 0.1 5.4 5 1 0 5 5 5 1 Galactose oxidase, central domain Urocanase_N PF17391.2 EGG17322.1 - 0.05 13.3 0.1 0.097 12.4 0.1 1.4 1 0 0 1 1 1 0 Urocanase N-terminal domain zf-UBR PF02207.20 EGG17322.1 - 6.6 7.0 11.1 3.8 7.7 3.9 3.1 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) Kelch_1 PF01344.25 EGG17323.1 - 4e-17 61.5 15.4 0.00081 18.9 0.1 5.9 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EGG17323.1 - 1.3e-16 60.2 9.4 2.3e-05 24.5 0.1 5.8 3 2 2 5 5 5 5 Kelch motif Kelch_4 PF13418.6 EGG17323.1 - 1.6e-14 53.6 11.1 0.00022 21.2 0.0 5.9 3 2 2 5 5 5 3 Galactose oxidase, central domain zf-B_box PF00643.24 EGG17323.1 - 1.4e-11 44.3 3.8 1.4e-11 44.3 3.8 2.3 2 0 0 2 2 2 1 B-box zinc finger Kelch_2 PF07646.15 EGG17323.1 - 1.8e-08 34.0 6.5 0.0085 16.0 0.0 5.0 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 EGG17323.1 - 1.4e-05 24.9 9.1 0.033 14.2 0.2 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EGG17323.1 - 0.016 15.5 6.3 2.7 8.4 0.0 5.1 5 1 0 5 5 5 0 Galactose oxidase, central domain Urocanase_N PF17391.2 EGG17323.1 - 0.038 13.7 0.4 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 Urocanase N-terminal domain zf-UBR PF02207.20 EGG17323.1 - 2.4 8.4 8.4 2 8.7 1.8 3.1 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) VPS9 PF02204.18 EGG17324.1 - 1.4e-26 92.8 0.8 5e-26 90.9 0.8 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain APH PF01636.23 EGG17324.1 - 1.7e-12 47.8 0.0 3e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pecanex_C PF05041.15 EGG17324.1 - 0.011 15.3 1.4 0.011 15.3 1.4 1.8 2 0 0 2 2 2 0 Pecanex protein (C-terminus) DUF641 PF04859.12 EGG17324.1 - 1.1 9.6 14.1 0.52 10.7 10.1 2.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Ferlin_C PF16165.5 EGG17324.1 - 5.7 6.9 19.9 0.041 13.8 3.4 3.5 2 1 1 3 3 3 0 Ferlin C-terminus GDP_Man_Dehyd PF16363.5 EGG17326.1 - 3.2e-63 214.1 0.0 3.7e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG17326.1 - 5.2e-60 202.9 0.0 6.5e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGG17326.1 - 2.8e-22 79.2 0.0 2.1e-21 76.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGG17326.1 - 1.3e-21 76.9 0.0 1.5e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGG17326.1 - 9.7e-16 57.7 0.0 1.4e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGG17326.1 - 5.8e-15 55.2 0.1 4.6e-13 48.9 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EGG17326.1 - 0.0033 17.3 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Ldh_1_N PF00056.23 EGG17326.1 - 0.15 12.1 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Ank_4 PF13637.6 EGG17327.1 - 5.5e-19 68.3 2.8 2.1e-09 37.7 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG17327.1 - 5.4e-14 52.1 1.9 1.6e-07 31.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG17327.1 - 1.4e-11 44.8 0.2 2.1e-11 44.2 0.2 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGG17327.1 - 9.7e-09 35.3 2.6 0.0007 19.9 1.2 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGG17327.1 - 7.4e-08 32.1 0.5 0.02 15.4 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Pkinase_Tyr PF07714.17 EGG17328.1 - 3.7e-50 170.6 0.0 5.6e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG17328.1 - 1.6e-43 148.9 0.0 5.3e-43 147.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain COR PF16095.5 EGG17328.1 - 4.5e-28 98.4 4.1 3.5e-20 72.6 0.6 2.8 2 0 0 2 2 2 2 C-terminal of Roc, COR, domain Roc PF08477.13 EGG17328.1 - 1.2e-13 51.4 3.8 5.6e-09 36.2 0.0 3.3 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 EGG17328.1 - 2e-12 46.7 33.3 1.9e-06 27.6 1.5 5.6 5 0 0 5 5 4 3 Leucine rich repeat Ras PF00071.22 EGG17328.1 - 1.2e-09 38.0 0.3 3.2e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 Ras family PH PF00169.29 EGG17328.1 - 2.6e-09 37.5 3.3 4.1e-09 36.9 0.8 2.8 2 0 0 2 2 1 1 PH domain LRR_4 PF12799.7 EGG17328.1 - 1.5e-08 34.8 52.5 5.1e-05 23.5 3.6 6.9 5 1 0 6 6 4 3 Leucine Rich repeats (2 copies) PH_11 PF15413.6 EGG17328.1 - 0.00018 21.9 0.4 0.0016 18.9 0.4 2.7 1 0 0 1 1 1 1 Pleckstrin homology domain Arf PF00025.21 EGG17328.1 - 0.0061 16.0 0.1 2.7 7.4 0.0 2.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Mcp5_PH PF12814.7 EGG17328.1 - 0.16 12.1 2.5 0.58 10.3 0.7 3.0 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology DUF1149 PF06619.11 EGG17328.1 - 0.17 12.2 1.8 1.4 9.2 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1149) MMR_HSR1 PF01926.23 EGG17328.1 - 0.2 11.7 3.5 0.26 11.4 0.3 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase WD40 PF00400.32 EGG17328.1 - 0.53 11.2 17.1 3.2 8.8 0.1 4.9 4 0 0 4 4 4 0 WD domain, G-beta repeat LRR_6 PF13516.6 EGG17328.1 - 9.4 6.6 22.6 4.8 7.5 0.1 6.2 6 0 0 6 6 6 0 Leucine Rich repeat CBS PF00571.28 EGG17329.1 - 5.5e-31 106.8 2.0 9.9e-09 35.5 0.0 4.2 4 0 0 4 4 4 4 CBS domain Nrap_D2 PF17403.2 EGG17329.1 - 0.019 14.7 0.1 0.16 11.7 0.0 2.2 2 1 0 2 2 2 0 Nrap protein PAP/OAS-like domain HSR PF03172.13 EGG17329.1 - 0.049 13.8 0.4 0.19 11.9 0.1 2.0 1 1 1 2 2 2 0 HSR domain Amino_oxidase PF01593.24 EGG17329.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase IFRD PF05004.13 EGG17330.1 - 1.9e-18 66.7 24.9 2.2e-16 59.9 24.9 2.9 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) SDA1 PF05285.12 EGG17330.1 - 0.0018 17.8 15.4 0.0028 17.1 15.4 1.3 1 0 0 1 1 1 1 SDA1 Na_trans_assoc PF06512.13 EGG17330.1 - 0.0063 16.8 10.6 0.0063 16.8 10.6 1.7 2 0 0 2 2 2 1 Sodium ion transport-associated Nop14 PF04147.12 EGG17330.1 - 0.072 11.3 17.0 0.14 10.4 17.0 1.4 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EGG17330.1 - 2.4 6.1 22.6 5.3 5.0 22.6 1.6 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 EGG17330.1 - 2.8 7.3 19.1 5 6.4 19.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4449 PF14613.6 EGG17331.1 - 0.0044 17.2 3.5 0.0044 17.2 3.5 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) Annexin PF00191.20 EGG17331.1 - 0.087 12.9 1.6 0.39 10.8 1.6 2.1 1 0 0 1 1 1 0 Annexin HD_assoc PF13286.6 EGG17331.1 - 0.65 10.6 5.1 1.6 9.3 0.6 3.0 2 0 0 2 2 2 0 Phosphohydrolase-associated domain adh_short PF00106.25 EGG17332.1 - 4e-48 163.5 0.1 6e-48 162.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG17332.1 - 6.3e-29 101.2 0.0 1.4e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG17332.1 - 4.2e-10 39.8 0.0 7.3e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 KR domain FNIP PF05725.12 EGG17332.1 - 2.1e-06 27.8 32.3 0.00028 21.0 2.2 7.1 6 2 1 7 7 7 3 FNIP Repeat Epimerase PF01370.21 EGG17332.1 - 5.7e-06 26.0 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGG17332.1 - 8.7e-06 25.7 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGG17332.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.10 EGG17332.1 - 0.016 14.6 0.5 0.034 13.5 0.1 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) LRR_5 PF13306.6 EGG17332.1 - 0.047 13.7 1.5 0.33 10.9 0.1 2.7 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 EGG17332.1 - 3.5 8.2 23.2 26 5.4 1.2 8.1 6 2 3 9 9 9 0 Leucine Rich repeats (2 copies) FNIP PF05725.12 EGG17333.1 - 1.9e-05 24.7 23.2 0.00047 20.3 0.6 6.7 6 1 1 7 7 7 4 FNIP Repeat SUIM_assoc PF16619.5 EGG17336.1 - 0.32 11.1 3.1 0.33 11.1 1.3 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FNIP PF05725.12 EGG17336.1 - 0.69 10.1 27.6 0.85 9.8 0.1 8.1 6 4 2 8 8 8 0 FNIP Repeat RICTOR_V PF14668.6 EGG17337.1 - 0.012 15.8 2.6 0.82 10.0 0.2 3.9 3 2 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 ALMT PF11744.8 EGG17339.1 - 2.1e-31 109.3 21.3 2.1e-31 109.3 21.3 2.6 2 1 1 3 3 3 1 Aluminium activated malate transporter FUSC_2 PF13515.6 EGG17339.1 - 2.8e-16 59.8 18.1 2.8e-16 59.8 18.1 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like FUSC PF04632.12 EGG17339.1 - 2.4e-13 49.5 2.1 2.4e-13 49.5 2.1 2.3 2 0 0 2 2 2 2 Fusaric acid resistance protein family PNPase PF03726.14 EGG17339.1 - 0.099 13.1 0.1 19 5.8 0.0 3.1 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Mer2 PF09074.10 EGG17339.1 - 0.14 11.9 6.3 5.5 6.7 0.2 2.9 2 0 0 2 2 2 0 Mer2 Tim17 PF02466.19 EGG17340.1 - 2e-27 95.8 6.6 3e-27 95.2 6.6 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PGK PF00162.19 EGG17341.1 - 1.1e-135 452.4 0.1 1.4e-135 452.1 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase SGIII PF15467.6 EGG17341.1 - 0.07 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Secretogranin-3 PGK PF00162.19 EGG17342.1 - 1.7e-146 488.0 1.7 1.9e-146 487.9 1.7 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FNIP PF05725.12 EGG17343.1 - 0.00039 20.5 2.3 0.61 10.3 2.6 3.3 3 0 0 3 3 3 2 FNIP Repeat NOA36 PF06524.12 EGG17343.1 - 4.3 6.6 7.9 8.1 5.7 7.9 1.5 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.13 EGG17343.1 - 6.4 6.8 8.1 9.4 6.3 8.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein FNIP PF05725.12 EGG17344.1 - 2.1e-05 24.6 24.5 0.00071 19.7 2.1 7.0 6 2 1 7 7 7 3 FNIP Repeat FNIP PF05725.12 EGG17346.1 - 0.55 10.4 15.6 2.1 8.6 0.2 6.5 3 2 1 4 4 4 0 FNIP Repeat Actin PF00022.19 EGG17347.1 - 5.2e-51 173.5 0.0 3.5e-50 170.8 0.0 1.9 1 1 0 1 1 1 1 Actin zf-rbx1 PF12678.7 EGG17348.1 - 8.2e-24 83.7 13.4 8.2e-24 83.7 13.4 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGG17348.1 - 3.3e-15 55.9 12.4 3.4e-15 55.9 9.7 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EGG17348.1 - 9.7e-05 22.6 14.2 0.0013 19.1 14.2 2.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG17348.1 - 0.00052 19.8 2.4 0.00052 19.8 2.4 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FNIP PF05725.12 EGG17348.1 - 0.014 15.6 0.4 0.014 15.6 0.4 6.2 5 2 4 9 9 9 0 FNIP Repeat zf-C3HC4 PF00097.25 EGG17348.1 - 0.041 13.7 11.1 0.34 10.8 11.1 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG17348.1 - 2.9 8.0 6.3 11 6.1 6.3 2.1 1 1 0 1 1 1 0 RING-type zinc-finger FNIP PF05725.12 EGG17349.1 - 0.41 10.9 34.3 0.31 11.2 0.4 8.1 6 2 2 8 8 8 0 FNIP Repeat FNIP PF05725.12 EGG17350.1 - 5.7e-05 23.2 22.0 0.047 13.8 0.2 7.6 4 2 3 8 8 8 5 FNIP Repeat DUF244 PF03112.14 EGG17350.1 - 0.018 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF LRR_4 PF12799.7 EGG17350.1 - 0.11 12.9 0.4 0.11 12.9 0.4 8.0 5 2 5 10 10 10 0 Leucine Rich repeats (2 copies) F-box PF00646.33 EGG17350.1 - 0.21 11.5 2.8 1.1 9.2 2.8 2.4 1 0 0 1 1 1 0 F-box domain HTH_23 PF13384.6 EGG17351.1 - 1.8e-08 34.0 0.1 2.5e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EGG17351.1 - 1.1e-07 31.9 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 EGG17351.1 - 2.8e-05 23.8 0.1 6.3e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 EGG17351.1 - 0.00011 21.6 0.1 0.00018 21.0 0.1 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_1 PF01527.20 EGG17351.1 - 0.00011 22.4 0.4 0.00023 21.4 0.1 1.6 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.6 EGG17351.1 - 0.00018 21.5 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix Dicty_spore_N PF04562.12 EGG17351.1 - 0.00038 21.1 11.4 0.00069 20.3 11.4 1.5 1 1 0 1 1 1 1 Dictyostelium spore coat protein, N terminus HTH_Tnp_ISL3 PF13542.6 EGG17351.1 - 0.00093 18.6 0.0 0.0022 17.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 TnsD PF15978.5 EGG17351.1 - 0.0019 17.2 0.3 0.0029 16.7 0.3 1.3 1 0 0 1 1 1 1 Tn7-like transposition protein D CENP-B_N PF04218.13 EGG17351.1 - 0.0021 17.7 0.1 0.0021 17.7 0.1 1.7 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain Phage_NinH PF06322.11 EGG17351.1 - 0.0026 17.6 0.1 0.0046 16.8 0.1 1.5 1 0 0 1 1 1 1 Phage NinH protein Mor PF08765.11 EGG17351.1 - 0.0048 16.9 0.1 0.0071 16.3 0.1 1.2 1 0 0 1 1 1 1 Mor transcription activator family Sigma70_r4_2 PF08281.12 EGG17351.1 - 0.012 15.3 0.1 0.021 14.5 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 FeoC PF09012.10 EGG17351.1 - 0.017 15.2 0.0 0.017 15.2 0.0 2.2 2 0 0 2 2 1 0 FeoC like transcriptional regulator KORA PF16509.5 EGG17351.1 - 0.029 14.6 0.1 0.046 14.0 0.1 1.3 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor HTH_DeoR PF08220.12 EGG17351.1 - 0.044 13.5 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 DeoR-like helix-turn-helix domain Bot1p PF12298.8 EGG17351.1 - 0.045 13.9 0.1 0.07 13.3 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein GerE PF00196.19 EGG17351.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.6 1 1 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_7 PF02796.15 EGG17351.1 - 0.062 13.4 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase RPA_C PF08784.11 EGG17351.1 - 0.08 13.6 0.4 0.17 12.6 0.0 1.7 2 0 0 2 2 1 0 Replication protein A C terminal PAX PF00292.18 EGG17351.1 - 0.089 12.7 0.1 0.089 12.7 0.1 1.5 2 0 0 2 2 1 0 'Paired box' domain adh_short PF00106.25 EGG17352.1 - 1.5e-48 164.9 0.0 2.7e-48 164.0 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG17352.1 - 1.6e-29 103.1 0.0 2.3e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG17352.1 - 4.3e-10 39.8 0.0 8.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG17352.1 - 9.8e-05 21.9 0.0 0.00014 21.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGG17352.1 - 0.00016 21.6 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGG17352.1 - 0.0019 17.8 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family QRPTase_C PF01729.19 EGG17352.1 - 0.018 14.8 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain RasGAP PF00616.19 EGG17353.1 - 8.4e-56 189.0 2.2 8.4e-56 189.0 2.2 2.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGG17353.1 - 6.6e-26 91.1 9.6 6.6e-26 91.1 9.6 2.3 2 0 0 2 2 2 1 RasGAP C-terminus Latarcin PF10279.9 EGG17353.1 - 0.15 12.5 4.6 1 9.8 1.6 3.1 1 1 1 2 2 2 0 Latarcin precursor FANCI_S3 PF14677.6 EGG17353.1 - 3.1 7.5 9.9 1.3 8.7 3.2 3.1 2 1 1 3 3 3 0 FANCI solenoid 3 MitMem_reg PF13012.6 EGG17353.1 - 4.1 7.9 11.0 5.9 7.4 2.6 4.1 3 2 1 4 4 4 0 Maintenance of mitochondrial structure and function Snapin_Pallidin PF14712.6 EGG17353.1 - 6.1 7.3 13.3 0.41 11.1 3.5 3.7 2 1 1 3 3 3 0 Snapin/Pallidin Inhibitor_G39P PF11417.8 EGG17354.1 - 0.087 13.4 1.2 6.1 7.4 0.0 3.1 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P Imm5 PF14423.6 EGG17354.1 - 0.2 11.9 2.4 0.36 11.0 0.1 2.5 2 0 0 2 2 2 0 Immunity protein Imm5 RabGAP-TBC PF00566.18 EGG17355.1 - 3.8e-40 137.8 7.4 3.8e-40 137.8 7.4 3.9 3 1 0 3 3 3 1 Rab-GTPase-TBC domain DMPK_coil PF08826.10 EGG17355.1 - 0.014 15.5 2.1 0.014 15.5 2.1 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like MRP-S28 PF10213.9 EGG17357.1 - 1.5e-12 48.1 0.3 1.5e-12 48.1 0.3 2.9 3 0 0 3 3 3 1 Mitochondrial ribosomal subunit protein STATa_Ig PF18214.1 EGG17357.1 - 0.37 10.8 2.9 1.4 8.9 2.9 2.0 1 0 0 1 1 1 0 STATa Immunoglobulin-like domain DTHCT PF08070.11 EGG17357.1 - 2.8 8.7 12.3 17 6.2 12.3 2.5 1 0 0 1 1 1 0 DTHCT (NUC029) region RlaP PF10127.9 EGG17358.1 - 3.4e-16 59.6 13.9 4.6e-11 42.8 13.6 2.7 2 1 0 2 2 2 2 RNA repair pathway DNA polymerase beta family Presenilin PF01080.17 EGG17358.1 - 5.2 5.7 9.8 9.1 4.9 9.8 1.3 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 EGG17358.1 - 7.6 7.6 9.7 3 8.9 2.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) CAP PF00188.26 EGG17359.1 - 2.3e-18 67.2 5.3 3.1e-13 50.6 0.2 3.8 2 1 0 2 2 2 2 Cysteine-rich secretory protein family MSP1_C PF07462.11 EGG17359.1 - 0.19 10.4 4.1 0.27 9.9 4.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Macoilin PF09726.9 EGG17359.1 - 2.1 6.8 5.7 2.5 6.6 5.7 1.1 1 0 0 1 1 1 0 Macoilin family Voltage_CLC PF00654.20 EGG17361.1 - 1.4e-95 320.6 26.0 2e-95 320.0 21.0 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 EGG17361.1 - 1e-10 41.9 0.1 0.00014 22.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain TAT_signal PF10518.9 EGG17361.1 - 0.001 18.8 2.4 0.001 18.8 2.4 2.6 3 0 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 EGG17361.1 - 0.008 15.5 1.4 0.025 13.9 1.4 1.8 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF4718 PF15842.5 EGG17361.1 - 0.063 13.1 1.3 0.14 12.0 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) DUF373 PF04123.13 EGG17361.1 - 1.4 8.2 11.0 0.041 13.3 3.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF373) Dicty_spore_N PF04562.12 EGG17363.1 - 3.2e-25 89.0 27.9 3.2e-25 89.0 27.9 4.1 4 2 0 5 5 5 2 Dictyostelium spore coat protein, N terminus Collagen PF01391.18 EGG17363.1 - 0.0039 16.9 8.6 0.0039 16.9 8.6 2.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) PT PF04886.12 EGG17363.1 - 0.59 9.7 41.8 5.2 6.7 5.6 4.8 2 1 1 3 3 3 0 PT repeat FH2 PF02181.23 EGG17364.1 - 2.6e-70 237.4 0.6 7.2e-69 232.7 0.0 2.9 4 0 0 4 4 4 1 Formin Homology 2 Domain DUF3361 PF11841.8 EGG17364.1 - 1.2e-13 51.3 0.0 3.2e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Drf_GBD PF06371.13 EGG17364.1 - 1.5e-06 27.9 0.2 4.2e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGG17364.1 - 0.051 13.2 0.1 0.14 11.8 0.1 1.8 1 0 0 1 1 1 0 Diaphanous FH3 Domain Arm PF00514.23 EGG17364.1 - 0.058 13.5 0.2 17 5.7 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat NUDIX PF00293.28 EGG17365.1 - 5.2e-07 29.8 0.1 1.6e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 NUDIX domain Sel1 PF08238.12 EGG17366.1 - 1.6e-64 212.8 62.4 8.5e-05 23.1 0.0 25.6 26 0 0 26 26 26 14 Sel1 repeat TPR_7 PF13176.6 EGG17366.1 - 6.5e-06 25.8 9.6 0.00036 20.3 0.0 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG17366.1 - 1.1e-05 25.7 24.6 5.4e-05 23.4 0.0 10.2 12 1 0 12 12 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGG17366.1 - 2.2e-05 24.1 7.9 0.01 15.7 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG17366.1 - 3.3e-05 24.4 5.5 0.39 11.4 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG17366.1 - 0.00021 21.4 15.4 0.81 10.0 0.0 8.7 8 2 1 9 9 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EGG17366.1 - 0.0008 19.1 0.0 0.0008 19.1 0.0 14.5 19 1 0 19 19 17 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG17366.1 - 0.0023 17.9 0.0 0.0023 17.9 0.0 15.3 22 0 0 22 22 18 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG17366.1 - 0.0055 16.8 0.0 0.031 14.4 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGG17366.1 - 0.02 15.5 0.2 0.59 10.9 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGG17366.1 - 0.057 13.6 0.0 0.057 13.6 0.0 15.5 19 2 1 20 20 18 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG17366.1 - 0.066 14.1 13.0 0.66 11.0 0.0 8.7 12 0 0 12 12 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG17366.1 - 0.16 12.7 54.0 3.7 8.4 0.0 15.6 18 2 1 19 19 16 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGG17366.1 - 0.19 12.3 0.0 0.19 12.3 0.0 9.7 12 0 0 12 12 12 0 Tetratricopeptide repeat KapB PF08810.10 EGG17367.1 - 0.012 15.7 0.3 0.017 15.3 0.3 1.3 1 0 0 1 1 1 0 Kinase associated protein B Glyco_hydro_31 PF01055.26 EGG17368.1 - 8.2e-144 480.0 9.2 1.1e-143 479.6 9.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EGG17368.1 - 2.3e-29 102.0 0.0 5.1e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EGG17368.1 - 6.1e-13 48.9 1.0 2.1e-12 47.1 0.4 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like EGF_2 PF07974.13 EGG17369.1 - 3.7e-05 24.0 15.3 9.5e-05 22.7 15.3 1.8 1 0 0 1 1 1 1 EGF-like domain DUF3844 PF12955.7 EGG17369.1 - 0.0003 20.9 0.5 0.0003 20.9 0.5 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3844) Chi-conotoxin PF16981.5 EGG17369.1 - 0.0016 18.7 0.2 0.0053 17.0 0.2 1.9 1 0 0 1 1 1 1 chi-Conotoxin or t superfamily EB PF01683.18 EGG17369.1 - 0.004 17.4 4.3 0.01 16.1 4.3 1.6 1 0 0 1 1 1 1 EB module I-EGF_1 PF18372.1 EGG17369.1 - 0.0053 16.8 9.0 0.012 15.7 9.0 1.6 1 0 0 1 1 1 1 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 EGG17369.1 - 0.0083 16.4 10.4 0.0083 16.4 10.4 2.2 2 0 0 2 2 2 1 EGF-like domain EGF_Tenascin PF18720.1 EGG17369.1 - 0.025 14.6 4.5 0.056 13.5 4.5 1.6 1 0 0 1 1 1 0 Tenascin EGF domain hEGF PF12661.7 EGG17369.1 - 0.16 12.7 15.1 0.026 15.2 10.3 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_CA PF07645.15 EGG17369.1 - 0.18 12.0 11.3 0.56 10.4 11.3 1.9 1 0 0 1 1 1 0 Calcium-binding EGF domain EGF_2 PF07974.13 EGG17370.1 - 3.6e-05 24.1 15.3 9.3e-05 22.7 15.3 1.8 1 0 0 1 1 1 1 EGF-like domain DUF3844 PF12955.7 EGG17370.1 - 7.4e-05 22.8 2.9 0.00029 20.9 0.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) EB PF01683.18 EGG17370.1 - 0.0038 17.5 4.3 0.01 16.1 4.3 1.6 1 0 0 1 1 1 1 EB module EGF PF00008.27 EGG17370.1 - 0.0081 16.4 10.4 0.0081 16.4 10.4 2.4 2 0 0 2 2 2 1 EGF-like domain I-EGF_1 PF18372.1 EGG17370.1 - 0.012 15.7 9.0 0.012 15.7 9.0 1.8 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 hEGF PF12661.7 EGG17370.1 - 0.025 15.2 10.3 0.025 15.2 10.3 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 EGG17370.1 - 0.026 14.6 4.5 0.055 13.5 4.5 1.5 1 0 0 1 1 1 0 Tenascin EGF domain EGF_CA PF07645.15 EGG17370.1 - 0.17 12.1 11.3 0.55 10.5 11.3 1.9 1 0 0 1 1 1 0 Calcium-binding EGF domain Ank_2 PF12796.7 EGG17371.1 - 4.8e-05 23.9 0.2 0.00035 21.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EGG17371.1 - 0.0046 16.9 19.0 0.073 13.0 2.3 5.0 3 1 0 3 3 3 2 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EGG17371.1 - 0.018 15.4 0.2 1 9.8 0.0 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG17371.1 - 0.071 13.7 0.3 6.9 7.4 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 EGG17371.1 - 0.24 11.9 0.7 11 6.7 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat zf-ZPR1 PF03367.13 EGG17372.1 - 1.1e-112 373.0 0.1 2.5e-55 186.7 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Zn-ribbon_8 PF09723.10 EGG17372.1 - 0.38 10.9 2.6 25 5.1 0.1 3.4 4 0 0 4 4 4 0 Zinc ribbon domain adh_short PF00106.25 EGG17373.1 - 1.8e-47 161.3 0.1 2.5e-47 160.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG17373.1 - 5e-36 124.4 0.1 6.4e-36 124.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG17373.1 - 5.7e-14 52.4 0.1 1.1e-13 51.6 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGG17373.1 - 6.8e-06 25.7 0.0 1.3e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EGG17373.1 - 7.1e-05 22.8 0.2 0.00011 22.2 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGG17373.1 - 0.0084 15.6 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGG17373.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGG17373.1 - 0.033 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 EGG17373.1 - 0.069 12.7 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family GRAM PF02893.20 EGG17374.1 - 2.1e-13 50.1 0.1 5.3e-13 48.9 0.1 1.7 1 0 0 1 1 1 1 GRAM domain V-SNARE_C PF12352.8 EGG17374.1 - 3.3e-09 36.9 8.7 7.1e-07 29.4 1.0 2.7 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 EGG17374.1 - 0.005 16.7 2.2 0.22 11.4 0.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5089) SNARE PF05739.19 EGG17374.1 - 0.023 14.7 0.2 0.023 14.7 0.2 3.0 3 0 0 3 3 3 0 SNARE domain Snapin_Pallidin PF14712.6 EGG17374.1 - 0.067 13.6 4.4 0.67 10.4 0.3 2.6 2 0 0 2 2 2 0 Snapin/Pallidin zf-DBF PF07535.12 EGG17375.1 - 3.4e-18 65.5 4.1 1e-17 63.9 4.1 1.9 1 0 0 1 1 1 1 DBF zinc finger Bunya_G2 PF03563.13 EGG17375.1 - 0.021 14.1 2.0 0.037 13.3 2.0 1.4 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Atg14 PF10186.9 EGG17376.1 - 4.7e-16 58.8 6.4 9.8e-11 41.3 0.0 3.1 1 1 2 3 3 3 2 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 EGG17376.1 - 0.0014 17.6 7.5 0.0014 17.6 7.5 2.3 2 1 0 2 2 2 1 Vacuolar protein sorting 38 Mac-1 PF09028.10 EGG17376.1 - 0.083 11.9 2.4 0.13 11.3 2.4 1.2 1 0 0 1 1 1 0 Mac 1 DUF501 PF04417.12 EGG17376.1 - 0.85 9.4 6.1 0.09 12.6 1.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF501) Acyl-ACP_TE PF01643.17 EGG17376.1 - 2 7.6 9.2 0.066 12.5 2.8 1.7 2 0 0 2 2 2 0 Acyl-ACP thioesterase MRP-L47 PF06984.13 EGG17377.1 - 3.9e-23 81.4 0.3 7.2e-23 80.5 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 EGG17377.1 - 4.9e-10 39.2 1.2 4.9e-10 39.2 1.2 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein DUF4918 PF16265.5 EGG17377.1 - 0.033 13.7 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4918) CBFB_NFYA PF02045.15 EGG17380.1 - 1e-24 86.9 11.0 4.3e-24 84.9 11.0 2.2 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Shisa PF13908.6 EGG17380.1 - 0.018 15.3 0.7 0.018 15.3 0.7 4.4 3 2 1 4 4 4 0 Wnt and FGF inhibitory regulator AAA_33 PF13671.6 EGG17381.1 - 3.1e-16 59.8 0.1 4.6e-14 52.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain 6PF2K PF01591.18 EGG17381.1 - 0.0018 17.6 0.0 0.0049 16.2 0.0 1.9 1 0 0 1 1 1 1 6-phosphofructo-2-kinase KTI12 PF08433.10 EGG17381.1 - 0.0077 15.7 1.5 0.81 9.1 0.0 3.0 2 1 1 3 3 3 2 Chromatin associated protein KTI12 tRNA_lig_kinase PF08303.11 EGG17381.1 - 0.023 14.8 4.8 0.054 13.6 0.6 3.2 3 1 0 3 3 3 0 tRNA ligase kinase domain Mg_chelatase PF01078.21 EGG17381.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI zf-C2H2_4 PF13894.6 EGG17382.1 - 0.037 14.9 2.7 0.057 14.3 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger MCU PF04678.13 EGG17382.1 - 0.083 13.0 0.3 0.083 13.0 0.3 3.3 3 1 0 3 3 3 0 Mitochondrial calcium uniporter DUF2391 PF09622.10 EGG17382.1 - 0.13 11.6 0.6 0.43 9.9 0.6 1.9 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) zf-C2H2 PF00096.26 EGG17382.1 - 0.17 12.4 0.2 0.17 12.4 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Synaptobrevin PF00957.21 EGG17383.1 - 1.8e-25 88.6 4.7 2.4e-25 88.1 4.7 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGG17383.1 - 5.1e-16 58.5 0.0 7.9e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF844 PF05815.11 EGG17383.1 - 0.0056 15.9 0.1 0.0076 15.5 0.1 1.2 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF844) Abhydrolase_6 PF12697.7 EGG17384.1 - 7e-05 23.5 0.0 8.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG17384.1 - 0.0015 18.3 0.1 0.0027 17.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold CENP-B_dimeris PF09026.10 EGG17385.1 - 0.11 12.9 6.6 0.35 11.3 6.6 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 EGG17385.1 - 0.29 10.8 4.7 0.49 10.1 4.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBD PF00786.28 EGG17386.1 - 9.1e-07 29.1 0.0 9.1e-07 29.1 0.0 3.3 3 1 0 3 3 3 1 P21-Rho-binding domain TPR_MLP1_2 PF07926.12 EGG17386.1 - 0.00018 21.6 79.3 0.028 14.5 15.7 5.3 1 1 2 4 4 4 3 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EGG17386.1 - 0.0005 20.1 18.5 0.0005 20.1 18.5 4.5 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 EGG17386.1 - 0.0027 17.9 23.5 0.0027 17.9 23.5 4.6 1 1 3 4 4 4 2 Tropomyosin like Filament PF00038.21 EGG17386.1 - 0.0036 16.9 68.9 0.0049 16.5 16.5 4.1 1 1 2 3 3 3 3 Intermediate filament protein APG6_N PF17675.1 EGG17386.1 - 0.87 10.1 81.6 0.16 12.5 10.1 4.5 1 1 3 4 4 4 0 Apg6 coiled-coil region Fez1 PF06818.15 EGG17386.1 - 0.96 9.9 71.1 0.32 11.4 31.1 4.2 2 1 2 4 4 4 0 Fez1 BING4CT PF08149.11 EGG17386.1 - 1.1 9.1 5.3 1.6 8.6 0.0 3.3 3 0 0 3 3 3 0 BING4CT (NUC141) domain Jnk-SapK_ap_N PF09744.9 EGG17386.1 - 5 7.3 73.3 0.2 11.9 14.1 4.6 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 Ank_2 PF12796.7 EGG17387.1 - 1.8e-08 34.8 4.8 2.8e-05 24.6 0.1 4.9 3 1 2 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG17387.1 - 1.1e-05 25.4 1.0 0.12 13.0 0.0 6.4 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 EGG17387.1 - 1.7e-05 25.3 4.0 0.013 16.1 0.0 5.3 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG17387.1 - 0.00016 21.9 0.1 0.28 11.6 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EGG17387.1 - 0.0021 18.4 1.8 0.0085 16.5 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeat Thioredoxin_16 PF18569.1 EGG17387.1 - 0.083 13.0 0.9 0.35 11.0 0.3 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain FDX-ACB PF03147.14 EGG17387.1 - 0.14 12.6 0.5 0.74 10.3 0.0 2.4 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF3447 PF11929.8 EGG17387.1 - 0.16 11.9 12.6 0.066 13.2 2.7 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF3447) ODR4-like PF14778.6 EGG17388.1 - 9.8e-80 268.3 4.7 9.8e-80 268.3 4.7 1.7 1 1 1 2 2 2 1 Olfactory receptor 4-like TMEM154 PF15102.6 EGG17388.1 - 0.013 15.4 1.3 0.013 15.4 1.3 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF5383 PF17355.2 EGG17388.1 - 0.027 14.9 3.7 0.066 13.6 3.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5383) HEPN_Toprim_N PF18871.1 EGG17388.1 - 0.12 12.3 1.6 0.3 11.0 0.8 2.1 2 1 0 2 2 2 0 HEPN/Toprim N-terminal domain 1 Pox_EPC_I2-L1 PF12575.8 EGG17388.1 - 0.47 10.7 2.2 1.1 9.6 0.4 2.6 2 1 1 3 3 3 0 Poxvirus entry protein complex L1 and I2 UCR_6-4kD PF08997.10 EGG17389.1 - 4.7e-05 23.2 0.2 6.3e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.9 EGG17389.1 - 0.022 14.8 1.5 0.062 13.4 1.5 1.8 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) CRAL_TRIO_2 PF13716.6 EGG17390.1 - 8.8e-42 142.5 1.1 1.1e-41 142.2 1.1 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 EGG17390.1 - 7.4e-07 29.0 0.2 1.6e-06 27.9 0.2 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain NOA36 PF06524.12 EGG17390.1 - 2.5 7.3 9.4 3.5 6.9 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein RCC1 PF00415.18 EGG17391.1 - 1.1e-36 125.2 0.8 3.5e-11 43.5 0.0 7.4 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG17391.1 - 6e-28 96.0 13.2 2e-08 33.8 0.1 6.6 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat NAM-associated PF14303.6 EGG17391.1 - 5.7 7.6 10.1 0.53 11.0 3.0 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain MFS_1 PF07690.16 EGG17392.1 - 9.9e-15 54.3 35.7 9.9e-15 54.3 35.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGG17392.1 - 5.7e-06 25.9 19.0 7.8e-06 25.4 19.0 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TMEM171 PF15471.6 EGG17392.1 - 0.55 9.2 5.5 1.4 7.8 5.5 1.7 1 0 0 1 1 1 0 Transmembrane protein family 171 Nop14 PF04147.12 EGG17392.1 - 6.2 4.9 23.6 10 4.2 23.6 1.2 1 0 0 1 1 1 0 Nop14-like family Ank_4 PF13637.6 EGG17393.1 - 0.0029 18.2 0.2 1.1e+02 3.5 0.1 6.0 5 1 1 6 6 6 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17393.1 - 0.024 15.1 0.3 1.4e+02 3.5 0.0 6.0 7 0 0 7 7 7 0 Ankyrin repeat DUF1053 PF06327.14 EGG17393.1 - 0.13 12.8 0.1 0.13 12.8 0.1 3.6 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1053) TFIIA PF03153.13 EGG17393.1 - 5.2 7.0 18.8 0.055 13.5 5.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ank_2 PF12796.7 EGG17395.1 - 5.7e-09 36.5 8.9 0.00035 21.1 0.1 5.2 2 2 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG17395.1 - 5.1e-06 26.6 4.5 1.3 9.5 0.1 7.2 6 1 2 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17395.1 - 9.1e-05 22.6 0.8 35 5.4 0.0 6.6 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 EGG17395.1 - 0.00018 22.0 11.8 0.004 17.7 0.0 5.7 7 1 1 8 8 8 3 Ankyrin repeats (many copies) MMR_HSR1 PF01926.23 EGG17396.1 - 1.1e-52 177.0 1.6 9.6e-26 90.1 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG17396.1 - 2.5e-26 92.0 0.3 6e-13 48.6 0.1 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 EGG17396.1 - 3e-15 56.3 0.2 1.5e-14 54.1 0.2 2.2 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal AIG1 PF04548.16 EGG17396.1 - 2.1e-14 53.4 18.2 1.2e-08 34.5 0.1 3.2 2 1 1 3 3 3 2 AIG1 family GTP_EFTU PF00009.27 EGG17396.1 - 1.1e-11 44.7 23.2 0.0003 20.4 0.1 5.8 3 1 1 4 4 4 3 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGG17396.1 - 1.7e-10 41.1 1.5 0.011 15.6 0.1 4.5 4 0 0 4 4 4 2 RsgA GTPase Ras PF00071.22 EGG17396.1 - 9.3e-10 38.3 2.9 0.00021 21.0 0.7 2.8 2 1 0 2 2 2 2 Ras family Arf PF00025.21 EGG17396.1 - 1.6e-09 37.4 3.0 5.1e-06 26.1 0.2 3.6 2 2 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 EGG17396.1 - 7.9e-09 35.8 3.9 0.0029 17.7 0.0 7.2 5 2 2 7 7 6 4 Dynamin family Roc PF08477.13 EGG17396.1 - 8.2e-08 32.5 1.5 4.1e-05 23.8 0.5 4.3 4 2 0 4 4 3 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGG17396.1 - 8.9e-08 31.8 4.2 0.00013 21.4 0.2 2.8 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EGG17396.1 - 0.0001 22.6 0.2 0.26 11.6 0.1 3.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EGG17396.1 - 0.00012 22.5 0.2 0.0044 17.4 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EGG17396.1 - 0.00035 20.2 4.1 0.78 9.3 0.1 4.5 3 2 1 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 EGG17396.1 - 0.00065 18.9 0.1 1.4 8.0 0.0 3.0 3 0 0 3 3 3 2 MCM P-loop domain AAA_33 PF13671.6 EGG17396.1 - 0.0024 18.1 1.4 0.22 11.7 0.1 3.8 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGG17396.1 - 0.0032 17.9 4.6 0.072 13.5 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain NTPase_1 PF03266.15 EGG17396.1 - 0.004 17.1 0.2 1.9 8.4 0.0 3.7 4 0 0 4 4 4 1 NTPase Ploopntkinase3 PF18751.1 EGG17396.1 - 0.008 16.1 0.0 3.7 7.4 0.0 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 MobB PF03205.14 EGG17396.1 - 0.025 14.5 0.1 9.2 6.2 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 EGG17396.1 - 0.063 13.0 0.0 10 6.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Glyco_hydro_30C PF17189.4 EGG17396.1 - 0.067 13.4 0.1 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain RNA_helicase PF00910.22 EGG17396.1 - 0.24 11.8 11.2 3.4 8.1 0.0 4.7 5 0 0 5 5 3 0 RNA helicase Nuc_deoxyri_tr2 PF15891.5 EGG17396.1 - 0.25 11.7 0.0 0.25 11.7 0.0 3.9 4 0 0 4 4 2 0 Nucleoside 2-deoxyribosyltransferase like AAA_18 PF13238.6 EGG17396.1 - 0.43 11.1 0.0 0.43 11.1 0.0 4.1 3 2 0 4 4 3 0 AAA domain BUD22 PF09073.10 EGG17396.1 - 0.7 9.2 46.8 0.13 11.6 43.3 1.5 2 0 0 2 2 1 0 BUD22 GCIP PF13324.6 EGG17396.1 - 2.9 7.4 25.3 1.4 8.5 12.0 2.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Peptidase_C48 PF02902.19 EGG17397.1 - 5.2e-43 147.4 0.6 5.2e-43 147.4 0.6 2.3 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain BING4CT PF08149.11 EGG17397.1 - 0.11 12.3 0.7 0.84 9.5 0.3 2.7 2 0 0 2 2 2 0 BING4CT (NUC141) domain SUIM_assoc PF16619.5 EGG17397.1 - 0.85 9.7 22.1 2.4 8.3 0.3 4.7 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 FAD_binding_3 PF01494.19 EGG17398.1 - 0.03 13.6 0.0 0.15 11.3 0.0 2.2 1 1 0 1 1 1 0 FAD binding domain RAWUL PF16207.5 EGG17398.1 - 0.068 13.8 0.0 0.21 12.3 0.0 1.9 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like GATA PF00320.27 EGG17399.1 - 4.3e-11 42.2 5.3 1e-10 41.0 5.3 1.7 1 0 0 1 1 1 1 GATA zinc finger PBP1_TM PF14812.6 EGG17399.1 - 0.32 11.4 8.2 10 6.6 0.1 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SAM_PNT PF02198.16 EGG17400.1 - 0.001 19.0 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain AAA_22 PF13401.6 EGG17400.1 - 0.047 14.0 0.0 0.44 10.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.15 EGG17400.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Amnionless PF14828.6 EGG17401.1 - 0.0068 15.3 0.2 0.16 10.8 0.0 2.2 2 0 0 2 2 2 2 Amnionless FeS_assembly_P PF01883.19 EGG17402.1 - 5.9e-07 29.6 1.1 9.6e-06 25.7 0.1 2.9 2 1 0 2 2 2 1 Iron-sulfur cluster assembly protein PQQ PF01011.21 EGG17402.1 - 0.019 14.9 1.2 1 9.4 0.5 2.8 2 0 0 2 2 2 0 PQQ enzyme repeat ChitinaseA_N PF08329.10 EGG17402.1 - 0.17 11.5 1.6 0.82 9.3 0.2 2.3 2 0 0 2 2 2 0 Chitinase A, N-terminal domain Amnionless PF14828.6 EGG17402.1 - 0.36 9.6 4.5 0.13 11.0 0.1 2.4 3 0 0 3 3 3 0 Amnionless Peroxin-13_N PF04088.13 EGG17402.1 - 0.64 10.3 4.6 0.27 11.5 0.5 2.5 3 0 0 3 3 3 0 Peroxin 13, N-terminal region Epimerase PF01370.21 EGG17403.1 - 2.8e-10 40.1 0.1 5.3e-08 32.6 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG17403.1 - 9.7e-08 31.8 1.3 0.00063 19.2 1.5 3.8 2 2 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGG17403.1 - 2.5e-07 30.8 0.8 4e-07 30.1 0.8 1.4 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGG17403.1 - 2.4e-06 26.8 1.5 0.00015 20.9 0.2 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EGG17403.1 - 0.00014 21.5 2.3 0.00025 20.7 2.3 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EGG17403.1 - 0.0023 17.4 0.5 0.0049 16.3 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EGG17403.1 - 0.006 15.7 0.2 0.01 15.0 0.2 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_2 PF03446.15 EGG17403.1 - 0.0061 16.7 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EGG17403.1 - 0.013 15.4 5.5 1.2 9.0 1.5 2.3 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 EGG17403.1 - 0.018 14.6 1.0 0.66 9.5 0.3 2.7 2 1 1 3 3 3 0 Enoyl-(Acyl carrier protein) reductase DXP_reductoisom PF02670.16 EGG17403.1 - 0.058 14.1 1.1 0.17 12.6 1.1 1.8 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TrkA_N PF02254.18 EGG17403.1 - 0.073 13.3 0.5 0.17 12.2 0.3 1.7 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.17 EGG17403.1 - 0.11 13.0 0.5 0.4 11.3 0.5 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MS_channel PF00924.18 EGG17404.1 - 9.3 5.7 5.7 2 7.9 1.6 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel BUD22 PF09073.10 EGG17405.1 - 1.3 8.3 20.3 1.8 7.8 20.3 1.3 1 0 0 1 1 1 0 BUD22 HATPase_c PF02518.26 EGG17406.1 - 6e-26 91.2 0.4 1.8e-25 89.6 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGG17406.1 - 9.8e-18 64.4 0.0 2.5e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGG17406.1 - 1e-14 54.3 0.0 3.8e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 EGG17406.1 - 1.2e-05 25.2 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain TH1 PF04858.13 EGG17407.1 - 6.7e-157 523.6 3.4 8.3e-157 523.3 3.4 1.0 1 0 0 1 1 1 1 TH1 protein DUF713 PF05218.14 EGG17407.1 - 0.4 10.4 4.9 0.19 11.4 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF713) Peptidase_C1 PF00112.23 EGG17408.1 - 5.5e-80 268.5 4.2 7e-80 268.2 4.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG17408.1 - 2.8e-12 46.9 3.3 5.3e-12 46.0 3.3 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGG17408.1 - 0.0075 15.1 3.0 0.5 9.1 0.6 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Plasmid_RAQPRD PF09686.10 EGG17409.1 - 0.12 12.6 0.8 5.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) F_actin_bund_C PF18060.1 EGG17410.1 - 5.3e-22 77.8 1.6 9.5e-22 76.9 1.6 1.4 1 0 0 1 1 1 1 F actin bundling C terminal EF-hand_5 PF13202.6 EGG17410.1 - 0.021 14.3 0.0 0.058 12.9 0.0 1.7 1 0 0 1 1 1 0 EF hand Dockerin_1 PF00404.18 EGG17410.1 - 0.13 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Dockerin type I domain ERM PF00769.19 EGG17410.1 - 0.38 10.5 3.7 0.76 9.5 3.7 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AbiJ_NTD4 PF18863.1 EGG17410.1 - 0.5 10.8 5.5 3.5 8.1 0.6 2.5 1 1 1 2 2 2 0 AbiJ N-terminal domain 4 ALG3 PF05208.13 EGG17411.1 - 5.3e-49 167.6 37.9 5.9e-49 167.4 33.3 2.6 2 1 0 2 2 2 1 ALG3 protein RNA_ligase PF09414.10 EGG17412.1 - 2.7e-18 66.8 0.1 4.3e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 RNA ligase RHD3 PF05879.12 EGG17413.1 - 4.8e-176 587.1 19.0 5.5e-176 586.9 19.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 EGG17413.1 - 4.9e-06 26.6 0.0 1.7e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGG17413.1 - 0.00055 20.0 0.0 0.0024 17.9 0.0 2.1 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 EGG17413.1 - 0.0044 17.3 0.0 0.0097 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGG17413.1 - 0.078 13.5 3.8 0.08 13.5 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_21 PF13304.6 EGG17413.1 - 0.28 10.9 0.0 0.28 10.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2722 PF10846.8 EGG17414.1 - 0.00017 20.7 1.6 0.00023 20.3 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Phage_cap_P2 PF05125.12 EGG17414.1 - 0.0025 16.9 0.8 0.0047 16.0 0.8 1.3 1 0 0 1 1 1 1 Phage major capsid protein, P2 family FHIPEP PF00771.20 EGG17414.1 - 0.19 10.2 0.6 0.33 9.4 0.6 1.3 1 0 0 1 1 1 0 FHIPEP family RRP14 PF15459.6 EGG17414.1 - 0.2 12.3 8.1 0.41 11.3 8.1 1.5 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Med3 PF11593.8 EGG17414.1 - 0.22 10.7 9.6 0.34 10.0 9.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FNIP PF05725.12 EGG17414.1 - 2.5 8.3 25.6 0.28 11.4 0.6 6.3 8 1 0 8 8 8 0 FNIP Repeat CTP_transf_like PF01467.26 EGG17415.1 - 0.028 14.6 0.5 0.34 11.1 0.1 2.5 2 0 0 2 2 2 0 Cytidylyltransferase-like Methyltransf_12 PF08242.12 EGG17415.1 - 0.46 11.3 1.9 1 10.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain FNIP PF05725.12 EGG17416.1 - 1.5e-10 41.1 42.9 0.022 14.9 0.1 10.5 10 1 1 11 11 11 5 FNIP Repeat LRR_8 PF13855.6 EGG17416.1 - 0.014 15.1 20.1 0.62 9.9 0.1 8.4 8 2 1 9 9 9 0 Leucine rich repeat CDC45 PF02724.14 EGG17416.1 - 7.5 4.7 16.1 0.66 8.2 9.2 2.2 3 0 0 3 3 3 0 CDC45-like protein TFIIA PF03153.13 EGG17416.1 - 8.5 6.3 26.2 0.019 15.0 13.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FNIP PF05725.12 EGG17417.1 - 8e-08 32.3 49.2 0.017 15.3 0.4 11.9 9 3 4 13 13 13 8 FNIP Repeat TMEM223 PF14640.6 EGG17417.1 - 0.014 15.5 0.5 0.63 10.2 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 223 CKS PF01111.19 EGG17418.1 - 0.012 15.9 0.7 6.6 7.1 0.0 3.5 3 0 0 3 3 3 0 Cyclin-dependent kinase regulatory subunit FNIP PF05725.12 EGG17418.1 - 0.033 14.4 27.2 19 5.5 0.0 8.0 5 2 3 8 8 8 0 FNIP Repeat PT PF04886.12 EGG17419.1 - 1e-05 24.9 3.1 1e-05 24.9 3.1 3.5 4 0 0 4 4 4 1 PT repeat Nop14 PF04147.12 EGG17419.1 - 0.11 10.6 12.0 0.16 10.2 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGG17419.1 - 0.52 8.5 5.1 0.7 8.1 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EGG17419.1 - 1.6 8.1 14.9 2.2 7.6 14.9 1.2 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 EGG17419.1 - 3.3 6.1 4.8 4.2 5.8 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CPSF100_C PF13299.6 EGG17419.1 - 6.6 6.9 8.0 16 5.7 8.0 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FNIP PF05725.12 EGG17420.1 - 5.1e-08 33.0 11.0 0.015 15.5 0.1 7.2 6 1 2 8 8 8 4 FNIP Repeat LRR_8 PF13855.6 EGG17420.1 - 0.021 14.6 5.0 0.76 9.6 0.0 4.8 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 EGG17420.1 - 1.4 9.4 20.0 13 6.4 0.1 7.7 6 3 3 9 9 9 0 Leucine Rich repeats (2 copies) Rap_GAP PF02145.15 EGG17421.1 - 1.3e-61 207.4 0.1 2.8e-61 206.3 0.1 1.6 1 0 0 1 1 1 1 Rap/ran-GAP FNIP PF05725.12 EGG17422.1 - 3e-09 36.9 20.7 0.0047 17.0 0.3 6.3 5 1 1 6 6 6 4 FNIP Repeat Peptidase_M1 PF01433.20 EGG17423.1 - 2.1e-45 155.0 0.1 3.9e-45 154.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EGG17423.1 - 8.8e-39 132.1 0.8 2.3e-38 130.7 0.8 1.8 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EGG17423.1 - 7.8e-23 81.6 0.3 4.5e-22 79.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Glyco_hydro_25 PF01183.20 EGG17423.1 - 0.039 14.1 0.1 0.17 12.0 0.1 2.2 2 1 0 2 2 2 0 Glycosyl hydrolases family 25 Mei5 PF10376.9 EGG17423.1 - 0.052 13.4 0.6 0.11 12.3 0.6 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein Peptidase_M48 PF01435.18 EGG17423.1 - 0.16 11.7 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M48 FNIP PF05725.12 EGG17424.1 - 0.23 11.7 34.6 0.23 11.7 1.5 7.0 5 4 0 5 5 5 0 FNIP Repeat LRR_8 PF13855.6 EGG17424.1 - 1 9.2 14.0 9.7 6.0 1.6 5.5 5 1 0 5 5 5 0 Leucine rich repeat FNIP PF05725.12 EGG17426.1 - 0.31 11.3 21.8 5.3 7.3 0.6 5.6 4 3 2 6 6 6 0 FNIP Repeat DUF3055 PF11256.8 EGG17427.1 - 0.003 17.8 1.7 0.21 11.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3055) FNIP PF05725.12 EGG17427.1 - 0.0061 16.7 10.5 0.66 10.2 0.1 6.2 5 2 0 5 5 5 2 FNIP Repeat DUF4571 PF15137.6 EGG17427.1 - 0.021 14.5 0.6 0.062 12.9 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) Melibiase_2 PF16499.5 EGG17428.1 - 1.5e-75 254.0 4.0 2.4e-75 253.4 4.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EGG17428.1 - 5.1e-21 74.5 0.6 1.4e-20 73.1 0.6 1.8 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 EGG17428.1 - 4.9e-06 26.7 0.0 9.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 EGG17428.1 - 5.8e-06 25.5 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Melibiase Glyco_hydro_30C PF17189.4 EGG17428.1 - 0.062 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain DUF3558 PF12079.8 EGG17428.1 - 0.16 11.9 0.4 0.28 11.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) zf-met2 PF12907.7 EGG17429.1 - 8.2e-16 57.9 2.8 1.5e-15 57.0 2.8 1.5 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 EGG17429.1 - 1.9e-07 31.9 11.2 3e-07 31.2 11.2 1.3 1 0 0 1 1 1 1 4F5 protein family Ribosomal_L34e PF01199.18 EGG17429.1 - 0.072 13.4 2.1 0.083 13.2 2.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L34e CemA PF03040.14 EGG17429.1 - 0.094 12.6 0.1 0.098 12.6 0.1 1.1 1 0 0 1 1 1 0 CemA family RRM_5 PF13893.6 EGG17430.1 - 5.2e-27 93.9 7.2 2.4e-20 72.4 0.2 3.9 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EGG17430.1 - 1.1e-12 47.5 0.2 0.00021 21.0 0.0 5.3 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TraQ PF09679.10 EGG17430.1 - 0.0083 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin chaperone (TraQ) RRM_8 PF11835.8 EGG17430.1 - 0.036 14.3 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 RRM-like domain RhoGEF PF00621.20 EGG17431.1 - 8.2e-22 78.3 8.8 1.4e-10 41.7 1.7 3.3 2 1 1 3 3 3 2 RhoGEF domain PH PF00169.29 EGG17431.1 - 0.00017 22.1 0.1 0.00044 20.7 0.1 1.7 1 0 0 1 1 1 1 PH domain CAF-1_p150 PF11600.8 EGG17431.1 - 0.056 13.1 44.8 0.16 11.6 44.8 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal EGF_2 PF07974.13 EGG17433.1 - 1e-14 54.6 116.0 9.6e-05 22.7 9.9 6.6 6 0 0 6 6 6 6 EGF-like domain DUF1198 PF06711.11 EGG17433.1 - 0.041 13.9 1.0 6.6 6.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) Phage_Mu_Gp45 PF06890.12 EGG17433.1 - 0.11 12.2 0.0 2.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Bacteriophage Mu Gp45 protein EGF PF00008.27 EGG17433.1 - 0.14 12.5 96.1 1.7 9.0 6.1 6.8 6 0 0 6 6 6 0 EGF-like domain LRR_8 PF13855.6 EGG17434.1 - 0.12 12.2 2.4 6 6.7 0.0 4.5 4 1 1 5 5 5 0 Leucine rich repeat EGF_2 PF07974.13 EGG17434.1 - 0.25 11.7 33.7 0.65 10.4 12.3 2.5 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 EGG17435.1 - 1.3e-05 25.4 33.5 0.00031 21.0 12.1 2.5 2 0 0 2 2 2 2 EGF-like domain LRR_4 PF12799.7 EGG17435.1 - 0.027 14.9 21.2 1.1 9.8 1.2 7.4 6 1 3 9 9 9 0 Leucine Rich repeats (2 copies) EGF PF00008.27 EGG17435.1 - 0.43 10.9 27.3 3.5 8.0 7.7 2.9 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 EGG17436.1 - 0.0065 16.8 9.4 0.0065 16.8 9.4 3.2 3 0 0 3 3 3 2 EGF-like domain EGF_Tenascin PF18720.1 EGG17436.1 - 0.02 14.9 26.8 0.58 10.3 8.4 2.9 2 0 0 2 2 2 0 Tenascin EGF domain EB PF01683.18 EGG17436.1 - 0.54 10.6 17.4 0.6 10.4 2.1 2.7 2 0 0 2 2 2 0 EB module I-EGF_1 PF18372.1 EGG17436.1 - 9.3 6.4 28.6 0.32 11.1 7.7 4.0 3 0 0 3 3 3 0 Integrin beta epidermal growth factor like domain 1 adh_short PF00106.25 EGG17437.1 - 9.8e-23 80.6 0.2 2.3e-22 79.4 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG17437.1 - 7.2e-14 51.9 0.0 1.3e-13 51.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG17437.1 - 3.7e-05 23.7 0.0 5.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGG17437.1 - 0.042 13.0 0.1 0.066 12.3 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 EGG17437.1 - 0.081 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Euplotes_phero PF05842.11 EGG17438.1 - 0.013 16.0 0.3 0.016 15.8 0.3 1.1 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein PRELI PF04707.14 EGG17439.1 - 2e-41 141.4 0.1 5e-41 140.1 0.0 1.6 2 0 0 2 2 2 1 PRELI-like family Phasin PF05597.11 EGG17439.1 - 2.3e-05 24.4 8.0 0.00046 20.2 1.6 2.2 1 1 1 2 2 2 2 Poly(hydroxyalcanoate) granule associated protein (phasin) Med28 PF11594.8 EGG17439.1 - 0.00027 21.0 3.0 0.0005 20.2 3.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 28 Apolipoprotein PF01442.18 EGG17439.1 - 0.0012 18.7 3.8 0.0019 18.1 3.8 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Histidinol_dh PF00815.20 EGG17439.1 - 0.021 13.9 4.6 0.028 13.4 3.9 1.5 2 0 0 2 2 2 0 Histidinol dehydrogenase ApoLp-III PF07464.11 EGG17439.1 - 0.022 14.9 4.2 0.04 14.0 3.9 1.6 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Chlorosome_CsmC PF11098.8 EGG17439.1 - 0.084 12.9 0.8 0.92 9.5 0.1 2.1 2 0 0 2 2 2 0 Chlorosome envelope protein C MCPsignal PF00015.21 EGG17439.1 - 0.085 12.7 4.9 0.24 11.2 5.1 1.6 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain IFT46_B_C PF12317.8 EGG17439.1 - 0.1 12.3 4.8 0.17 11.6 3.6 1.7 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Ribosomal_S20p PF01649.18 EGG17439.1 - 0.11 13.1 3.7 0.26 11.9 1.5 2.6 1 1 2 3 3 3 0 Ribosomal protein S20 DUF883 PF05957.13 EGG17439.1 - 0.14 12.8 3.9 2.6 8.7 3.9 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 EGG17439.1 - 0.17 12.2 2.4 0.45 10.8 1.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MIEAP PF16026.5 EGG17439.1 - 0.2 11.9 4.3 0.31 11.2 4.3 1.3 1 0 0 1 1 1 0 Mitochondria-eating protein YojJ PF10372.9 EGG17439.1 - 0.23 11.6 5.1 6.1 7.0 0.4 2.5 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus LMBR1 PF04791.16 EGG17439.1 - 0.24 10.2 3.5 0.29 10.0 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CPG4 PF15481.6 EGG17439.1 - 0.31 11.7 1.8 10 6.8 0.1 2.5 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 DUF87 PF01935.17 EGG17439.1 - 0.45 10.6 4.2 0.77 9.8 3.9 1.5 1 1 0 1 1 1 0 Helicase HerA, central domain DUF5446 PF17522.2 EGG17439.1 - 0.99 9.6 11.9 2.9 8.1 1.3 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5446) DUF1993 PF09351.10 EGG17439.1 - 0.99 9.5 4.0 5.2 7.2 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) ING PF12998.7 EGG17439.1 - 1.2 9.7 6.8 4.1 8.0 6.9 2.0 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding YtxH PF12732.7 EGG17439.1 - 1.4 9.5 8.7 31 5.2 3.0 2.6 1 1 1 2 2 2 0 YtxH-like protein TMPIT PF07851.13 EGG17439.1 - 1.7 7.8 5.9 1.2 8.3 4.3 1.5 1 1 0 1 1 1 0 TMPIT-like protein Prefoldin PF02996.17 EGG17439.1 - 2.7 7.9 9.5 3.2 7.7 1.3 2.4 1 1 1 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 EGG17439.1 - 3.7 7.7 6.2 14 5.9 5.6 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LRR_4 PF12799.7 EGG17440.1 - 0.0001 22.6 12.7 8.2 7.0 0.0 8.3 6 2 3 9 9 9 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGG17440.1 - 0.0038 17.1 0.4 0.0093 15.8 0.4 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 EGG17440.1 - 0.045 13.5 4.3 30 4.5 0.0 5.5 6 1 0 6 6 6 0 Leucine rich repeat FNIP PF05725.12 EGG17440.1 - 3.6 7.8 22.5 0.33 11.2 0.2 6.2 4 3 1 5 5 5 0 FNIP Repeat LRR_4 PF12799.7 EGG17441.1 - 0.00039 20.7 1.3 0.0059 17.0 0.5 2.6 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG17441.1 - 0.028 14.2 0.9 0.13 12.0 0.5 2.0 1 1 1 2 2 2 0 Leucine rich repeat FNIP PF05725.12 EGG17442.1 - 2.8e-10 40.2 45.2 0.00028 21.0 0.3 10.9 11 2 2 13 13 13 5 FNIP Repeat DUF5032 PF16435.5 EGG17442.1 - 0.0011 18.5 0.2 0.35 10.3 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5032) NERD PF08378.11 EGG17442.1 - 0.17 12.4 1.6 0.46 11.0 0.5 2.2 2 0 0 2 2 2 0 Nuclease-related domain LRR_9 PF14580.6 EGG17442.1 - 0.32 10.5 4.0 1 8.8 0.1 3.2 3 0 0 3 3 3 0 Leucine-rich repeat BSMAP PF12280.8 EGG17442.1 - 4.1 7.6 9.2 1.8 8.8 1.7 2.8 3 0 0 3 3 3 0 Brain specific membrane anchored protein FNIP PF05725.12 EGG17443.1 - 2.5e-08 34.0 13.8 5.7e-05 23.2 0.3 6.4 5 1 1 6 6 6 2 FNIP Repeat LRR_8 PF13855.6 EGG17443.1 - 0.02 14.6 2.8 0.64 9.8 0.2 3.5 3 0 0 3 3 3 0 Leucine rich repeat IL6 PF00489.17 EGG17443.1 - 0.027 14.1 0.2 0.06 12.9 0.2 1.5 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family FNIP PF05725.12 EGG17444.1 - 1.3e-08 34.8 33.0 0.0024 18.0 0.2 10.4 11 2 1 12 12 12 3 FNIP Repeat NERD PF08378.11 EGG17444.1 - 0.0079 16.6 0.1 8.2 6.9 0.0 2.6 2 0 0 2 2 2 2 Nuclease-related domain RecU PF03838.14 EGG17444.1 - 0.1 12.6 0.4 1.5 8.8 0.2 2.6 2 0 0 2 2 2 0 Recombination protein U FNIP PF05725.12 EGG17445.1 - 7.9e-08 32.3 19.5 7.1e-05 22.9 1.0 5.6 6 0 0 6 6 6 2 FNIP Repeat EGF_Tenascin PF18720.1 EGG17446.1 - 0.0038 17.2 10.0 0.009 16.0 10.0 1.7 1 0 0 1 1 1 1 Tenascin EGF domain CD34_antigen PF06365.12 EGG17446.1 - 0.071 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family AgrD PF05931.11 EGG17446.1 - 0.31 11.1 2.5 1 9.5 0.1 2.8 3 0 0 3 3 3 0 Staphylococcal AgrD protein EGF_2 PF07974.13 EGG17446.1 - 1.1 9.7 13.4 2.1 8.8 13.4 1.5 1 0 0 1 1 1 0 EGF-like domain FNIP PF05725.12 EGG17447.1 - 3.1e-09 36.8 0.0 0.58 10.4 0.0 5.9 4 1 1 5 5 5 3 FNIP Repeat LRR_4 PF12799.7 EGG17447.1 - 0.19 12.2 5.6 15 6.2 0.2 5.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) FNIP PF05725.12 EGG17449.1 - 0.23 11.7 21.2 7.1 6.9 0.0 7.6 8 2 0 8 8 8 0 FNIP Repeat FNIP PF05725.12 EGG17450.1 - 3.8e-06 27.0 75.1 0.15 12.3 0.5 16.4 16 3 1 17 17 17 9 FNIP Repeat DUF4118 PF13493.6 EGG17450.1 - 0.074 12.8 5.1 12 5.7 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) FNIP PF05725.12 EGG17452.1 - 3.2e-07 30.4 47.9 0.00037 20.6 0.6 10.9 10 4 3 13 13 13 5 FNIP Repeat LRR_5 PF13306.6 EGG17452.1 - 0.083 12.8 0.6 6.9 6.6 0.0 3.7 4 0 0 4 4 4 0 BspA type Leucine rich repeat region (6 copies) AMPKBI PF04739.15 EGG17452.1 - 0.44 10.9 7.1 27 5.1 0.0 4.8 4 1 0 4 4 4 0 5'-AMP-activated protein kinase beta subunit, interaction domain LRR_8 PF13855.6 EGG17452.1 - 1.9 8.3 38.1 1.1 9.0 1.4 8.5 7 2 2 9 9 9 0 Leucine rich repeat FNIP PF05725.12 EGG17453.1 - 0.12 12.6 0.3 0.12 12.6 0.3 6.6 6 2 0 6 6 6 0 FNIP Repeat FNIP PF05725.12 EGG17454.1 - 0.00025 21.2 14.2 0.24 11.6 0.5 5.9 5 1 1 6 6 6 3 FNIP Repeat DUF2722 PF10846.8 EGG17454.1 - 0.068 12.1 6.9 0.099 11.6 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 EGG17454.1 - 0.87 9.2 14.5 0.16 11.6 10.2 1.9 2 0 0 2 2 2 0 Spt20 family LRR_8 PF13855.6 EGG17454.1 - 1 9.1 8.6 2.1 8.2 0.2 4.2 4 1 0 4 4 4 0 Leucine rich repeat DUF2967 PF11179.8 EGG17454.1 - 4.1 5.4 6.0 6.1 4.8 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) FNIP PF05725.12 EGG17455.1 - 7.5e-09 35.6 65.7 0.00074 19.6 0.3 14.9 14 3 3 18 18 18 8 FNIP Repeat Secapin PF17521.2 EGG17455.1 - 2 8.3 4.7 4.5 7.1 0.1 3.6 4 0 0 4 4 4 0 Honey bee peptides Ribosom_S12_S23 PF00164.25 EGG17456.1 - 1.7e-48 162.9 0.7 3.5e-48 162.0 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S12/S23 HTH_3 PF01381.22 EGG17456.1 - 4.9e-14 52.1 1.1 1.1e-13 51.0 1.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EGG17456.1 - 0.00023 21.1 1.8 0.00037 20.5 0.5 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 EGG17456.1 - 0.0017 18.6 0.5 0.0033 17.7 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.6 EGG17456.1 - 0.0027 17.6 0.4 0.0059 16.5 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTHP PF11534.8 EGG17456.1 - 0.0036 17.7 0.0 0.94 9.9 0.0 2.4 2 0 0 2 2 2 1 Hexameric tyrosine-coordinated heme protein (HTHP) MBF1 PF08523.10 EGG17456.1 - 0.02 15.3 0.0 0.059 13.8 0.0 1.8 1 0 0 1 1 1 0 Multiprotein bridging factor 1 MqsA_antitoxin PF15731.5 EGG17456.1 - 0.031 14.4 0.1 0.056 13.6 0.1 1.4 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA tRNA-synt_2 PF00152.20 EGG17457.1 - 1.4e-78 264.1 0.0 2e-78 263.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGG17457.1 - 1.8e-10 40.6 0.0 3.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGG17457.1 - 8.7e-07 28.7 0.0 0.0078 15.7 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ints3 PF10189.9 EGG17458.1 - 3.2e-89 298.0 6.2 5.6e-88 294.0 0.0 3.2 3 0 0 3 3 3 2 Integrator complex subunit 3 Baculo_IE-1 PF05290.11 EGG17458.1 - 0.11 12.5 0.5 0.4 10.6 0.5 2.0 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Acyltransferase PF01553.21 EGG17459.1 - 1.2e-15 57.3 0.0 2.1e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase LRR_4 PF12799.7 EGG17460.1 - 4.2e-12 46.1 40.2 0.0016 18.8 0.8 7.6 4 1 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG17460.1 - 3.3e-11 42.8 31.7 5.3e-06 26.1 0.3 5.8 3 1 5 8 8 8 5 Leucine rich repeat LRR_6 PF13516.6 EGG17460.1 - 0.0015 18.4 35.3 0.33 11.1 0.1 10.0 10 0 0 10 10 10 2 Leucine Rich repeat FNIP PF05725.12 EGG17460.1 - 1.5 9.0 5.2 31 4.9 0.2 3.8 3 1 1 4 4 4 0 FNIP Repeat LRR_5 PF13306.6 EGG17460.1 - 1.6 8.7 5.2 33 4.4 0.2 3.1 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 EGG17460.1 - 4 6.9 17.9 0.33 10.5 0.9 3.8 2 2 1 3 3 3 0 Leucine-rich repeat Ribosomal_L1 PF00687.21 EGG17461.1 - 7.1e-26 91.2 4.6 7.1e-26 91.2 4.6 2.4 2 1 1 3 3 3 1 Ribosomal protein L1p/L10e family Phage_connect_1 PF05135.13 EGG17461.1 - 0.74 10.4 3.8 2.3 8.8 0.2 3.0 2 1 1 3 3 3 0 Phage gp6-like head-tail connector protein SWI-SNF_Ssr4 PF08549.10 EGG17461.1 - 3.2 6.3 25.4 4.2 5.9 25.4 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Beta-lactamase2 PF13354.6 EGG17462.1 - 1.8e-23 83.2 0.0 3.5e-22 79.0 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase enzyme family DsbB PF02600.16 EGG17462.1 - 0.082 13.3 0.0 0.53 10.7 0.0 2.2 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB BB_PF PF18063.1 EGG17463.1 - 7.4e-92 306.6 23.3 2.3e-50 171.1 6.5 3.2 2 2 0 2 2 2 2 Beta barrel Pore-forming domain FAM177 PF14774.6 EGG17464.1 - 8.2e-16 58.4 4.0 1.3e-15 57.8 4.0 1.3 1 0 0 1 1 1 1 FAM177 family Glyco_transf_15 PF01793.16 EGG17464.1 - 0.011 15.0 4.8 0.013 14.8 4.8 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase PPL5 PF18168.1 EGG17464.1 - 0.013 14.8 8.7 0.087 12.1 0.8 2.0 1 1 0 2 2 2 0 Prim-pol family 5 Spt20 PF12090.8 EGG17464.1 - 1.8 8.1 19.1 0.44 10.1 15.4 1.6 2 0 0 2 2 2 0 Spt20 family DUF612 PF04747.12 EGG17464.1 - 2.9 6.9 12.9 0.21 10.7 8.4 1.3 2 0 0 2 2 2 0 Protein of unknown function, DUF612 RNA_pol PF00940.19 EGG17465.1 - 2.8e-164 546.9 0.0 1.1e-163 544.9 0.0 2.1 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EGG17465.1 - 1.7e-41 142.8 1.8 1.1e-39 136.8 1.8 3.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Lectin_N PF03954.14 EGG17465.1 - 0.06 13.1 0.3 0.06 13.1 0.3 4.0 4 0 0 4 4 4 0 Hepatic lectin, N-terminal domain GRDP-like PF07173.12 EGG17465.1 - 7.3 7.2 12.0 0.96 10.1 0.4 3.2 3 0 0 3 3 3 0 Glycine-rich domain-containing protein-like Glyco_hydro_35 PF01301.19 EGG17465.1 - 8.8 5.8 11.5 0.49 10.0 5.7 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 CRIM PF16978.5 EGG17466.1 - 9.7e-06 25.8 0.1 0.011 15.8 0.0 3.3 2 0 0 2 2 2 2 SAPK-interacting protein 1 (Sin1), middle CRIM domain EGF_2 PF07974.13 EGG17467.1 - 2.3e-05 24.7 15.0 2.3e-05 24.7 15.0 4.1 5 0 0 5 5 5 1 EGF-like domain Utp14 PF04615.13 EGG17467.1 - 2.1 6.8 15.4 2.6 6.5 15.4 1.1 1 0 0 1 1 1 0 Utp14 protein SDA1 PF05285.12 EGG17467.1 - 8.4 5.7 16.3 12 5.2 16.3 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 EGG17467.1 - 8.6 5.0 18.6 18 4.0 18.6 1.5 1 0 0 1 1 1 0 Presenilin HSP20 PF00011.21 EGG17469.1 - 0.13 12.4 3.4 0.15 12.3 0.0 2.8 3 0 0 3 3 3 0 Hsp20/alpha crystallin family Oxysterol_BP PF01237.18 EGG17470.1 - 1.1e-108 363.4 0.9 1.1e-108 363.4 0.9 1.4 2 0 0 2 2 2 1 Oxysterol-binding protein RhoGAP PF00620.27 EGG17471.1 - 6.6e-35 120.2 0.2 1.5e-34 119.1 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EGG17471.1 - 4.2e-29 101.1 2.3 1.9e-21 76.5 0.4 3.1 2 0 0 2 2 2 2 PH domain F-box-like PF12937.7 EGG17471.1 - 1.8e-10 40.6 0.7 4.1e-10 39.4 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG17471.1 - 2.3e-07 30.5 0.9 7.7e-07 28.8 0.9 2.0 1 0 0 1 1 1 1 F-box domain PH_3 PF14593.6 EGG17471.1 - 5.7e-07 29.6 0.4 9.9e-06 25.6 0.0 3.0 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 EGG17471.1 - 1.1e-06 29.0 4.3 4e-05 24.0 0.1 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.6 EGG17471.1 - 0.00065 19.9 1.9 0.0025 18.0 0.1 2.8 4 0 0 4 4 4 1 Pleckstrin homology domain PGP_phosphatase PF09419.10 EGG17471.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase PH_17 PF18012.1 EGG17471.1 - 0.052 13.3 0.0 0.78 9.5 0.0 2.4 2 0 0 2 2 2 0 PH domain Abhydrolase_1 PF00561.20 EGG17472.1 - 6.5e-07 29.2 0.4 0.00067 19.4 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG17472.1 - 0.0019 17.5 0.0 0.0049 16.2 0.0 1.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGG17472.1 - 0.019 14.7 0.2 0.047 13.4 0.2 1.7 2 0 0 2 2 2 0 PGAP1-like protein WH2 PF02205.20 EGG17473.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.3 2 0 0 2 2 2 0 WH2 motif EGF_2 PF07974.13 EGG17474.1 - 0.084 13.3 12.9 0.19 12.1 12.9 1.6 1 0 0 1 1 1 0 EGF-like domain LRR_8 PF13855.6 EGG17474.1 - 0.087 12.6 3.1 0.32 10.8 1.6 2.7 2 0 0 2 2 2 0 Leucine rich repeat Defensin_2 PF01097.18 EGG17474.1 - 0.18 11.8 3.9 0.41 10.6 3.9 1.6 1 0 0 1 1 1 0 Arthropod defensin Laminin_EGF PF00053.24 EGG17474.1 - 1.1 9.5 7.9 2.8 8.1 7.9 1.7 1 0 0 1 1 1 0 Laminin EGF domain LRR_4 PF12799.7 EGG17474.1 - 4.8 7.7 13.7 7 7.2 2.0 5.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Actin PF00022.19 EGG17475.1 - 7.6e-150 499.0 0.0 2.5e-149 497.4 0.0 1.7 1 1 0 1 1 1 1 Actin GBP PF02263.19 EGG17476.1 - 2.6e-43 148.2 0.0 6.8e-43 146.8 0.0 1.7 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGG17476.1 - 3.6e-09 36.4 0.0 3.6e-09 36.4 0.0 2.6 2 1 1 3 3 3 1 Guanylate-binding protein, C-terminal domain Spore_III_AB PF09548.10 EGG17476.1 - 4.4 7.4 10.4 5.8 7.0 8.8 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Pkinase PF00069.25 EGG17478.1 - 1.7e-19 70.2 0.9 2.2e-10 40.4 0.0 2.8 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG17478.1 - 7.2e-06 25.5 0.1 8.2e-05 22.0 0.0 2.4 2 1 1 3 3 3 1 Protein tyrosine kinase TFIIA PF03153.13 EGG17478.1 - 4.2 7.3 17.4 5.3 6.9 17.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UCH PF00443.29 EGG17479.1 - 1.6e-74 250.7 3.7 2.9e-45 154.8 0.1 3.5 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGG17479.1 - 3.8e-22 78.7 0.1 3.8e-22 78.7 0.1 4.6 6 0 0 6 6 6 1 DUSP domain UCH_1 PF13423.6 EGG17479.1 - 9.5e-05 22.1 28.2 0.64 9.6 5.9 4.8 3 1 1 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase DUF4834 PF16118.5 EGG17479.1 - 0.0067 17.4 1.7 0.0067 17.4 1.7 3.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4834) DUF5470 PF17564.2 EGG17479.1 - 0.095 12.9 0.5 0.41 10.9 0.5 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5470) Androgen_recep PF02166.16 EGG17479.1 - 0.92 8.3 13.8 1.9 7.3 13.8 1.4 1 0 0 1 1 1 0 Androgen receptor ANAPC8 PF04049.13 EGG17479.1 - 4.6 7.3 10.1 0.24 11.4 3.2 2.4 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 RNA_pol_Rbc25 PF08292.12 EGG17479.1 - 4.6 7.5 8.3 11 6.3 0.4 2.8 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 TFIIA PF03153.13 EGG17479.1 - 7 6.5 26.9 0.25 11.3 14.6 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 EGG17480.1 - 9.2 4.8 46.3 12 4.4 46.3 1.1 1 0 0 1 1 1 0 Hamartin protein LRR_4 PF12799.7 EGG17481.1 - 0.0021 18.4 10.4 0.86 10.1 0.7 5.1 2 2 2 5 5 5 4 Leucine Rich repeats (2 copies) DUF3844 PF12955.7 EGG17483.1 - 0.013 15.7 19.8 0.19 11.9 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3844) TIG PF01833.24 EGG17483.1 - 0.4 10.8 18.4 0.22 11.6 4.2 4.3 3 2 0 3 3 3 0 IPT/TIG domain PLDc PF00614.22 EGG17484.1 - 3.2e-15 55.6 1.2 3.7e-08 33.2 0.2 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGG17484.1 - 1.3e-12 47.7 0.8 4.5e-06 26.6 0.1 3.6 3 0 0 3 3 3 2 PLD-like domain EF-hand_7 PF13499.6 EGG17484.1 - 2.9e-05 24.4 0.4 0.36 11.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGG17484.1 - 3.3e-05 23.5 0.3 0.39 10.8 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGG17484.1 - 4.3e-05 23.3 1.1 0.0095 15.8 0.1 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGG17484.1 - 7.7e-05 22.0 0.5 0.19 11.4 0.0 2.8 2 0 0 2 2 2 2 EF hand PH PF00169.29 EGG17484.1 - 0.013 16.0 0.4 0.046 14.2 0.1 2.2 2 0 0 2 2 2 0 PH domain EF-hand_5 PF13202.6 EGG17484.1 - 0.045 13.3 0.4 0.51 9.9 0.1 2.6 3 0 0 3 3 3 0 EF hand Calreticulin PF00262.18 EGG17485.1 - 2.6e-140 467.4 7.6 4.4e-140 466.7 7.6 1.4 1 0 0 1 1 1 1 Calreticulin family TIG PF01833.24 EGG17485.1 - 0.00067 19.7 2.4 0.00067 19.7 2.4 3.3 4 0 0 4 4 4 1 IPT/TIG domain EGF_2 PF07974.13 EGG17485.1 - 0.6 10.5 7.7 1.7 9.1 7.7 1.8 1 0 0 1 1 1 0 EGF-like domain Phosphodiest PF01663.22 EGG17486.1 - 2.3e-09 37.3 0.1 5.3e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase FAM176 PF14851.6 EGG17486.1 - 1.3 8.6 8.6 0.51 10.0 0.1 2.8 2 0 0 2 2 2 0 FAM176 family Secretin_N_2 PF07655.13 EGG17487.1 - 0.8 10.3 16.0 3.7 8.2 9.2 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Las1 PF04031.13 EGG17487.1 - 2.6 8.2 5.0 6.8 6.8 5.0 1.7 1 1 0 1 1 1 0 Las1-like DUF3698 PF12479.8 EGG17488.1 - 3.2 8.3 0.0 3.2 8.3 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3698) DUF3123 PF11321.8 EGG17488.1 - 7.1 7.3 11.3 16 6.2 1.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3123) HutD PF05962.11 EGG17489.1 - 2.2e-25 89.7 0.0 1.3e-23 83.9 0.0 2.4 2 0 0 2 2 2 2 HutD Pkinase_Tyr PF07714.17 EGG17490.1 - 1.1e-52 178.9 0.0 2.9e-52 177.5 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG17490.1 - 3.3e-49 167.6 0.0 1.3e-48 165.7 0.0 2.1 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 EGG17490.1 - 9.8e-16 58.1 0.1 8.5e-09 35.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17490.1 - 5.5e-11 42.8 0.1 2.4e-08 34.4 0.0 3.4 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG17490.1 - 1.3e-08 34.9 0.1 0.00035 20.8 0.1 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17490.1 - 4.6e-06 26.6 0.2 0.021 15.3 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EGG17490.1 - 0.00013 22.3 0.8 0.0019 18.5 0.1 3.1 2 1 0 2 2 2 1 Ankyrin repeat Kinase-like PF14531.6 EGG17490.1 - 0.0015 17.9 0.1 0.0072 15.7 0.1 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGG17490.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 EGG17492.1 - 3.6e-15 56.1 10.3 0.00017 22.3 0.1 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat Robl_LC7 PF03259.17 EGG17492.1 - 1.3e-07 31.3 0.0 3.1e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Roadblock/LC7 domain ANAPC4_WD40 PF12894.7 EGG17492.1 - 4.2e-06 27.0 2.0 6.6 7.1 0.0 5.0 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG17492.1 - 0.003 16.9 0.0 0.0086 15.4 0.0 1.8 1 0 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 EGG17492.1 - 0.012 14.3 0.0 0.071 11.7 0.0 2.1 1 1 0 2 2 2 0 Nucleoporin Nup120/160 LAMTOR5 PF16672.5 EGG17492.1 - 0.075 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 PQQ_3 PF13570.6 EGG17492.1 - 0.093 13.3 0.0 32 5.2 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain Arf PF00025.21 EGG17493.1 - 1.3e-30 106.1 0.1 1.6e-30 105.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGG17493.1 - 2.2e-08 33.9 0.0 2.5e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG17493.1 - 4.7e-08 33.3 0.0 6.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGG17493.1 - 9.3e-07 28.4 0.1 1.5e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGG17493.1 - 1.1e-06 28.1 0.3 1.4e-06 27.8 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG17493.1 - 0.0012 18.9 0.1 0.002 18.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGG17493.1 - 0.013 15.3 0.1 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EGG17493.1 - 0.02 14.6 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EGG17493.1 - 0.027 14.4 0.1 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Myosin_head PF00063.21 EGG17494.1 - 3.4e-47 161.1 0.5 4.6e-47 160.7 0.5 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) FcoT PF10862.8 EGG17494.1 - 0.011 15.4 0.6 0.018 14.7 0.6 1.3 1 0 0 1 1 1 0 FcoT-like thioesterase domain Senescence PF06911.12 EGG17494.1 - 0.19 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Senescence-associated protein Myosin_head PF00063.21 EGG17495.1 - 5.8e-52 176.9 10.0 1.2e-38 132.9 0.0 3.0 3 0 0 3 3 3 2 Myosin head (motor domain) AAA_16 PF13191.6 EGG17495.1 - 0.0019 18.6 0.0 0.0037 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG17495.1 - 0.023 15.0 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGG17495.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Pex14_N PF04695.13 EGG17496.1 - 0.43 11.2 9.4 1 10.0 9.4 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PBP1_TM PF14812.6 EGG17496.1 - 3.2 8.2 13.2 2.2 8.7 4.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4320 PF14208.6 EGG17497.1 - 0.0033 17.5 0.4 0.024 14.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4320) Abhydrolase_1 PF00561.20 EGG17497.1 - 0.0041 16.8 0.4 0.011 15.4 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG17497.1 - 0.0058 15.9 0.0 0.011 15.0 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG17497.1 - 0.039 14.5 0.0 0.054 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family SWIRM-assoc_2 PF16496.5 EGG17498.1 - 6.4e-59 199.9 23.2 6.4e-59 199.9 23.2 9.0 4 2 2 8 8 3 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 EGG17498.1 - 1.8e-17 63.5 0.1 8.9e-17 61.2 0.1 2.4 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EGG17498.1 - 1.1e-14 54.2 7.3 1.1e-14 54.2 7.3 3.5 3 0 0 3 3 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EGG17498.1 - 6.9e-09 35.8 0.2 4.7e-08 33.1 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain BRCT PF00533.26 EGG17498.1 - 0.00019 21.7 0.0 0.001 19.4 0.0 2.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain SDA1 PF05285.12 EGG17498.1 - 0.0025 17.3 28.4 0.0025 17.3 28.4 8.6 4 2 3 7 7 2 1 SDA1 PTCB-BRCT PF12738.7 EGG17498.1 - 0.0038 17.1 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 EGG17498.1 - 0.013 15.9 0.2 0.12 12.8 0.2 2.8 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain DUF3439 PF11921.8 EGG17498.1 - 0.015 15.3 1.1 0.015 15.3 1.1 9.4 8 2 1 9 9 8 0 Domain of unknown function (DUF3439) NiFe-hyd_HybE PF11939.8 EGG17498.1 - 0.23 11.3 3.1 0.13 12.1 0.3 2.0 2 0 0 2 2 2 0 [NiFe]-hydrogenase assembly, chaperone, HybE AT_hook PF02178.19 EGG17498.1 - 0.28 11.2 4.9 0.82 9.8 4.9 1.9 1 0 0 1 1 1 0 AT hook motif SNF2_N PF00176.23 EGG17499.1 - 2.1e-44 151.7 0.9 8.9e-44 149.6 0.0 2.4 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG17499.1 - 7.2e-17 61.7 0.1 1.6e-15 57.4 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG17499.1 - 1.8e-05 24.6 0.0 8.6e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EGG17499.1 - 0.00037 19.8 0.1 0.00037 19.8 0.1 3.2 4 0 0 4 4 4 1 ERCC3/RAD25/XPB C-terminal helicase AAA_34 PF13872.6 EGG17499.1 - 0.00038 19.5 0.1 0.0012 17.8 0.1 1.8 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 AAA_14 PF13173.6 EGG17499.1 - 0.0023 17.9 0.0 0.024 14.7 0.0 2.8 1 0 0 1 1 1 1 AAA domain DUF4476 PF14771.6 EGG17500.1 - 7.8e-14 51.8 0.6 1.6e-13 50.8 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) C2 PF00168.30 EGG17500.1 - 3.2e-11 43.4 0.2 8e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 C2 domain Mito_carr PF00153.27 EGG17501.1 - 2.7e-71 235.6 2.8 1.6e-25 88.8 0.0 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein ER_lumen_recept PF00810.18 EGG17501.1 - 1.4e-53 181.6 18.2 1.5e-53 181.6 11.4 2.3 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EGG17501.1 - 2 8.2 12.0 0.53 10.1 1.1 3.4 3 0 0 3 3 3 0 PQ loop repeat LUD_dom PF02589.15 EGG17502.1 - 0.0011 18.8 1.0 0.46 10.2 0.0 2.3 2 0 0 2 2 2 2 LUD domain TpcC PF12642.7 EGG17502.1 - 0.012 15.4 0.9 0.021 14.7 0.9 1.3 1 0 0 1 1 1 0 Conjugative transposon protein TcpC Op_neuropeptide PF08035.11 EGG17502.1 - 0.11 12.4 0.2 0.35 10.8 0.2 1.9 1 0 0 1 1 1 0 Opioids neuropeptide TPX2 PF06886.11 EGG17502.1 - 0.66 10.3 11.0 2 8.7 11.0 1.8 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Presenilin PF01080.17 EGG17502.1 - 0.82 8.4 4.0 20 3.8 5.8 2.1 2 0 0 2 2 2 0 Presenilin Pex26 PF07163.12 EGG17502.1 - 1.4 8.2 9.3 0.25 10.6 3.2 2.3 1 1 1 2 2 2 0 Pex26 protein Ank_2 PF12796.7 EGG17503.1 - 0.014 16.0 0.6 4.7 7.9 0.0 3.9 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Peptidase_M8 PF01457.16 EGG17504.1 - 3.5e-49 167.9 1.6 3.5e-49 167.9 1.6 2.4 1 1 1 2 2 2 1 Leishmanolysin OKR_DC_1_N PF03709.15 EGG17504.1 - 0.058 13.7 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Methyltransf_11 PF08241.12 EGG17505.1 - 4e-12 46.6 0.0 9.6e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG17505.1 - 1e-10 42.1 0.0 4.3e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG17505.1 - 1.7e-09 37.7 0.1 1.7e-09 37.7 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG17505.1 - 1e-07 32.6 0.1 1e-07 32.6 0.1 3.3 3 1 2 5 5 5 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG17505.1 - 1e-05 25.0 2.4 1e-05 25.0 0.6 1.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGG17505.1 - 0.0019 18.0 0.2 0.0058 16.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGG17505.1 - 0.0044 17.0 0.1 0.0044 17.0 0.1 3.3 2 1 0 2 2 2 1 Methyltransferase domain Bacillus_HBL PF05791.11 EGG17505.1 - 0.067 13.0 33.8 0.12 12.2 14.6 3.7 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF4407 PF14362.6 EGG17505.1 - 9.3 5.5 19.1 2.7 7.3 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Proteasome PF00227.26 EGG17506.1 - 3e-48 163.8 0.0 3.7e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGG17506.1 - 3.7e-11 42.5 0.2 6.9e-11 41.6 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Homeodomain PF00046.29 EGG17506.1 - 0.13 12.2 0.2 0.23 11.3 0.2 1.4 1 0 0 1 1 1 0 Homeodomain GpcrRhopsn4 PF10192.9 EGG17507.1 - 1e-48 166.0 30.6 1e-48 166.0 30.6 2.3 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Glyco_transf_22 PF03901.17 EGG17507.1 - 9.2e-48 163.5 32.0 9.2e-48 163.5 32.0 3.4 2 1 0 3 3 3 1 Alg9-like mannosyltransferase family Glyco_transf_8 PF01501.20 EGG17508.1 - 6e-07 29.3 0.4 6e-07 29.3 0.4 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGG17508.1 - 0.00018 21.0 0.4 0.00035 20.0 0.4 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative DUF4856 PF16148.5 EGG17508.1 - 0.0017 17.4 0.1 0.0025 16.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4856) O-antigen_lig PF13425.6 EGG17508.1 - 0.049 12.4 0.6 0.07 11.9 0.6 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein T2SSM PF04612.12 EGG17508.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF4407 PF14362.6 EGG17508.1 - 0.5 9.7 2.2 0.84 8.9 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WD40_3 PF15911.5 EGG17510.1 - 0.0041 17.1 0.8 4.1 7.5 0.1 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat Orthopox_35kD PF02250.15 EGG17510.1 - 0.023 14.4 0.3 3.5 7.3 0.1 2.1 2 0 0 2 2 2 0 35kD major secreted virus protein BNR_2 PF13088.6 EGG17510.1 - 0.04 13.2 0.2 0.89 8.8 0.0 2.0 2 0 0 2 2 2 0 BNR repeat-like domain DUF1522 PF07482.11 EGG17510.1 - 0.053 13.8 2.3 2.4 8.5 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) DUF2157 PF09925.9 EGG17510.1 - 0.087 12.6 0.4 0.16 11.7 0.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) SabA_adhesion PF18304.1 EGG17510.1 - 0.11 11.7 5.8 0.053 12.8 0.9 2.0 1 1 1 2 2 2 0 SabA N-terminal extracellular adhesion domain IP_trans PF02121.18 EGG17511.1 - 4.8e-111 370.2 0.1 5.4e-111 370.1 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Prenylcys_lyase PF07156.14 EGG17511.1 - 0.035 13.2 0.1 0.09 11.9 0.1 1.6 2 0 0 2 2 2 0 Prenylcysteine lyase Pyridoxal_deC PF00282.19 EGG17512.1 - 1.8e-23 82.9 0.0 4.1e-23 81.7 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGG17512.1 - 1.2e-08 34.4 0.0 1.6e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGG17512.1 - 3e-06 26.7 0.0 1.9e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II SepSecS PF05889.13 EGG17512.1 - 3.9e-05 22.5 0.0 0.00017 20.4 0.0 1.8 2 0 0 2 2 2 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DegT_DnrJ_EryC1 PF01041.17 EGG17512.1 - 0.00052 19.4 0.0 0.00084 18.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family FliE PF02049.18 EGG17513.1 - 0.36 11.0 3.8 0.44 10.7 0.7 2.5 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE eRF1_2 PF03464.15 EGG17514.1 - 1.3e-44 151.7 0.0 3.3e-44 150.4 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGG17514.1 - 2.1e-36 124.9 0.0 6.6e-36 123.2 0.0 1.9 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EGG17514.1 - 2.1e-16 60.1 0.0 4.4e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EGG17514.1 - 1.3e-09 38.5 0.1 3e-09 37.3 0.0 1.6 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EGG17514.1 - 2e-07 31.4 0.0 3.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF4512 PF14975.6 EGG17514.1 - 0.7 10.7 4.7 0.41 11.5 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) Amidinotransf PF02274.17 EGG17518.1 - 2.6e-17 62.9 0.0 2.5e-14 53.1 0.0 2.9 1 1 0 1 1 1 1 Amidinotransferase EcKinase PF02958.20 EGG17519.1 - 2.7e-11 43.4 1.2 2.4e-09 36.9 0.2 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 EGG17519.1 - 2.4e-06 27.7 0.0 4.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGG17519.1 - 4.5e-06 25.8 0.6 9.6e-06 24.7 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Actin PF00022.19 EGG17521.1 - 7.4e-40 136.8 0.0 1.3e-30 106.3 0.0 2.1 1 1 0 2 2 2 2 Actin FtsA PF14450.6 EGG17521.1 - 0.0041 17.5 0.6 0.0083 16.5 0.6 1.6 1 1 0 1 1 1 1 Cell division protein FtsA DPBB_1 PF03330.18 EGG17523.1 - 4.6e-06 26.8 4.3 1.2e-05 25.5 0.5 3.0 2 1 0 2 2 2 1 Lytic transglycolase I-EGF_1 PF18372.1 EGG17523.1 - 0.065 13.3 0.8 0.16 12.1 0.8 1.7 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Mu-like_Com PF10122.9 EGG17523.1 - 0.11 12.0 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com GST_N_2 PF13409.6 EGG17524.1 - 1.3e-10 41.4 0.0 2.9e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGG17524.1 - 4.2e-08 33.4 0.0 9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG17524.1 - 2.2e-07 31.0 0.0 3.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG17524.1 - 1.1e-05 25.5 0.1 1.9e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGG17524.1 - 1.8e-05 25.0 0.0 3.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGG17524.1 - 2.9e-05 24.0 0.0 5.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain KOW PF00467.29 EGG17525.1 - 2.1e-22 78.3 15.3 1.5e-05 24.8 0.7 7.1 7 0 0 7 7 7 5 KOW motif Spt5-NGN PF03439.13 EGG17525.1 - 5.9e-22 77.4 0.0 1.2e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF2187 PF09953.9 EGG17525.1 - 0.011 15.7 0.1 0.047 13.7 0.1 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) SH3_2 PF07653.17 EGG17525.1 - 0.026 14.2 0.1 0.19 11.5 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain Nucleoporin_FG PF13634.6 EGG17526.1 - 0.00043 21.1 23.3 0.00043 21.1 23.3 18.8 8 5 8 16 16 16 7 Nucleoporin FG repeat region MttA_Hcf106 PF02416.16 EGG17526.1 - 0.15 11.4 2.1 0.75 9.2 2.1 2.3 1 0 0 1 1 1 0 mttA/Hcf106 family zf-RanBP PF00641.18 EGG17526.1 - 1.9 7.9 22.7 3.8 6.9 7.1 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others E1_DerP2_DerF2 PF02221.15 EGG17527.1 - 7.5e-22 78.2 0.2 8.5e-22 78.0 0.2 1.1 1 0 0 1 1 1 1 ML domain DUF4625 PF15418.6 EGG17527.1 - 0.051 13.8 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) Gp5_C PF06715.12 EGG17527.1 - 0.15 12.3 0.9 0.38 11.0 0.9 1.7 1 0 0 1 1 1 0 Gp5 C-terminal repeat (3 copies) E1_DerP2_DerF2 PF02221.15 EGG17528.1 - 1.4e-17 64.4 0.0 2.1e-17 63.8 0.0 1.3 1 1 0 1 1 1 1 ML domain Mic1 PF07035.12 EGG17529.1 - 2.1e-46 157.5 1.8 4.9e-46 156.3 1.8 1.6 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like DUF3947 PF13135.6 EGG17529.1 - 0.018 15.2 0.4 0.066 13.4 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) F-box-like PF12937.7 EGG17530.1 - 0.013 15.3 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 F-box-like SR-25 PF10500.9 EGG17530.1 - 0.015 14.9 11.4 0.015 14.9 11.4 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Glyco_hydro_4C PF11975.8 EGG17530.1 - 0.025 14.6 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Orf78 PF06024.12 EGG17530.1 - 7.8 6.9 6.7 8 6.8 2.2 2.5 2 0 0 2 2 2 0 Orf78 (ac78) CobT PF06213.12 EGG17531.1 - 0.026 13.9 17.4 0.037 13.4 17.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2052 PF09747.9 EGG17531.1 - 0.11 12.6 12.1 0.14 12.3 12.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TFB6 PF17110.5 EGG17531.1 - 0.24 11.1 0.9 0.43 10.3 0.9 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH GAGA_bind PF06217.12 EGG17531.1 - 0.4 10.9 9.4 0.38 11.0 9.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family TFIIA PF03153.13 EGG17531.1 - 0.82 9.6 43.1 0.94 9.4 43.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 EGG17531.1 - 1.6 8.7 19.7 1.9 8.4 19.7 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 EGG17531.1 - 3.6 7.6 9.9 3.4 7.7 9.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 EGG17531.1 - 6 6.6 15.0 7.1 6.4 15.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 EGG17531.1 - 8.7 4.3 13.5 8.1 4.4 13.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HEAT PF02985.22 EGG17532.1 - 4.9e-07 29.5 2.5 0.034 14.4 0.1 4.7 4 0 0 4 4 4 3 HEAT repeat Cnd1 PF12717.7 EGG17532.1 - 0.00022 21.3 10.7 0.3 11.1 1.1 5.2 4 2 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGG17532.1 - 0.00049 20.4 0.5 0.28 11.6 0.1 3.8 4 0 0 4 4 4 1 HEAT repeats PPP4R2 PF09184.11 EGG17532.1 - 0.0053 16.4 18.0 0.0053 16.4 18.0 6.3 4 1 0 5 5 5 1 PPP4R2 Spt20 PF12090.8 EGG17532.1 - 0.0053 16.4 32.6 0.0053 16.4 32.6 5.3 3 2 1 4 4 4 1 Spt20 family DcuA_DcuB PF03605.14 EGG17532.1 - 3.5 6.4 5.9 0.53 9.1 0.7 2.2 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter Hydin_ADK PF17213.3 EGG17532.1 - 3.7 7.8 0.0 3.7 7.8 0.0 6.2 7 0 0 7 7 7 0 Hydin Adenylate kinase-like domain NPH3 PF03000.14 EGG17533.1 - 0.036 13.7 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 NPH3 family MSP7_C PF12948.7 EGG17534.1 - 1.2 9.7 23.6 0.43 11.3 0.5 4.2 3 1 1 4 4 4 0 MSP7-like protein C-terminal domain Telomere_reg-2 PF10193.9 EGG17534.1 - 4.6 7.7 6.6 7.2 7.1 0.1 3.7 3 1 1 4 4 4 0 Telomere length regulation protein UME PF08064.13 EGG17536.1 - 0.13 12.2 7.7 2.5 8.1 1.1 4.4 3 1 0 3 3 3 0 UME (NUC010) domain RhoGAP PF00620.27 EGG17537.1 - 1.4e-37 128.9 0.1 2.4e-37 128.1 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain ATG_C PF09333.11 EGG17537.1 - 6.7e-11 42.4 0.1 2.3e-10 40.7 0.1 1.9 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EGG17537.1 - 0.021 14.6 1.0 0.042 13.6 0.2 2.0 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Ribosomal_60s PF00428.19 EGG17538.1 - 5.7e-25 87.7 12.5 6.7e-25 87.5 12.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Hc1 PF07432.13 EGG17538.1 - 0.79 10.1 12.0 1.2 9.6 12.0 1.2 1 0 0 1 1 1 0 Histone H1-like protein Hc1 DNA_methylase PF00145.17 EGG17539.1 - 3.1e-33 115.5 0.5 2.1e-32 112.8 0.5 2.2 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase RPAP3_C PF13877.6 EGG17539.1 - 0.064 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 DUF4751 PF15942.5 EGG17541.1 - 0.049 13.6 0.1 0.072 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4751) RRM_1 PF00076.22 EGG17542.1 - 9.3e-26 89.5 2.2 1e-11 44.4 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG17542.1 - 5.1e-12 45.5 0.5 2.7e-05 23.7 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG17542.1 - 2.5e-05 24.1 0.1 0.26 11.2 0.1 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Coilin_N PF15862.5 EGG17542.1 - 0.0017 18.2 4.5 0.0024 17.7 4.5 1.3 1 0 0 1 1 1 1 Coilin N-terminus Limkain-b1 PF11608.8 EGG17542.1 - 0.002 18.2 0.8 0.19 11.8 0.2 2.5 2 0 0 2 2 2 1 Limkain b1 DUF4523 PF15023.6 EGG17542.1 - 0.01 15.7 0.9 0.029 14.2 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4523) RF-1 PF00472.20 EGG17542.1 - 0.02 14.8 5.5 0.46 10.4 3.8 2.5 3 0 0 3 3 3 0 RF-1 domain SET_assoc PF11767.8 EGG17542.1 - 0.024 14.3 0.1 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated VIT1 PF01988.19 EGG17542.1 - 0.13 12.1 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 VIT family Med19 PF10278.9 EGG17542.1 - 0.79 9.6 9.4 1.5 8.7 6.5 2.3 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Colicin-DNase PF12639.7 EGG17542.1 - 2.5 9.0 7.3 1.2 10.0 3.8 2.1 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin B_lectin PF01453.24 EGG17543.1 - 0.13 12.8 1.3 0.47 11.0 0.4 2.2 2 0 0 2 2 2 0 D-mannose binding lectin EGF_2 PF07974.13 EGG17543.1 - 0.49 10.8 13.5 1.1 9.7 13.5 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGG17543.1 - 0.51 11.1 6.8 1.4 9.7 6.8 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF Ribosomal_L5e PF17144.4 EGG17544.1 - 1.4e-81 272.3 0.9 2.2e-81 271.6 0.9 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EGG17544.1 - 1.7e-28 99.4 7.7 1.7e-28 99.4 7.7 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF3496 PF12001.8 EGG17544.1 - 2.3 8.7 7.5 0.44 10.9 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) MBOAT PF03062.19 EGG17545.1 - 3.9e-50 171.2 9.8 3.9e-50 171.2 9.8 1.9 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family BAR_3 PF16746.5 EGG17546.1 - 4.9e-72 242.5 11.5 7.9e-72 241.8 11.5 1.3 1 0 0 1 1 1 1 BAR domain of APPL family ArfGap PF01412.18 EGG17546.1 - 2.3e-38 130.9 3.1 5.1e-38 129.8 0.1 3.1 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.29 EGG17546.1 - 5.6e-13 49.3 0.1 1.4e-12 48.1 0.1 1.7 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.7 EGG17546.1 - 3.7e-12 46.7 2.6 4.4e-07 30.4 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17546.1 - 4.7e-11 43.0 0.2 0.00056 20.4 0.2 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG17546.1 - 7.3e-09 35.7 0.1 7.2e-07 29.4 0.0 3.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17546.1 - 7.6e-07 29.0 0.4 1.8 9.4 0.1 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EGG17546.1 - 6.6e-05 23.2 1.2 5.5 7.6 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat BAR PF03114.18 EGG17546.1 - 0.0001 22.0 6.2 0.00022 21.0 6.2 1.5 1 0 0 1 1 1 1 BAR domain PH_8 PF15409.6 EGG17546.1 - 0.00032 20.9 0.1 0.011 16.0 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EGG17546.1 - 0.00048 20.5 0.4 0.032 14.6 0.4 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain IMD PF08397.11 EGG17546.1 - 0.9 8.9 11.6 4.6 6.6 0.5 2.5 1 1 1 2 2 2 0 IRSp53/MIM homology domain adh_short PF00106.25 EGG17547.1 - 4.3e-41 140.5 0.0 6.1e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG17547.1 - 1.8e-26 93.2 0.0 2.5e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG17547.1 - 7.1e-06 26.0 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EGG17547.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Metallophos PF00149.28 EGG17548.1 - 1.1e-19 71.7 3.1 4.3e-19 69.8 3.2 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EGG17548.1 - 2.2e-19 69.8 3.7 2.2e-19 69.8 3.7 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 EGG17548.1 - 6.4e-14 52.6 0.3 2.8e-13 50.5 0.3 2.2 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 EGG17548.1 - 0.0035 17.5 0.0 0.012 15.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 EGG17548.1 - 0.074 13.6 0.1 0.16 12.5 0.1 1.5 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Ank_5 PF13857.6 EGG17549.1 - 9.7e-26 89.5 2.5 6.6e-12 45.4 0.1 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG17549.1 - 3.2e-25 88.5 3.1 1.9e-09 38.0 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17549.1 - 4.5e-24 84.5 0.7 1.5e-08 35.0 0.0 6.1 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17549.1 - 1.6e-21 74.1 1.8 6.9e-06 26.0 0.0 6.8 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 EGG17549.1 - 5.7e-21 74.0 8.7 3.9e-06 27.1 0.1 5.5 6 0 0 6 6 6 3 Ankyrin repeat V-ATPase_C PF03223.15 EGG17550.1 - 7e-117 390.9 7.7 8.2e-117 390.7 7.7 1.0 1 0 0 1 1 1 1 V-ATPase subunit C CtIP_N PF10482.9 EGG17550.1 - 0.054 13.5 0.3 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Baculo_PEP_C PF04513.12 EGG17550.1 - 3.7 7.6 10.9 25 4.9 10.9 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ketoacyl-synt PF00109.26 EGG17554.1 - 2.4e-80 269.8 0.0 5.1e-80 268.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG17554.1 - 6.8e-54 183.5 0.0 1.2e-53 182.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EGG17554.1 - 2e-40 138.6 0.3 1e-39 136.3 0.0 2.5 3 0 0 3 3 2 1 KR domain Ketoacyl-synt_C PF02801.22 EGG17554.1 - 1.4e-38 131.5 0.1 8.7e-37 125.7 0.0 3.5 4 0 0 4 4 3 1 Beta-ketoacyl synthase, C-terminal domain Chal_sti_synt_N PF00195.19 EGG17554.1 - 9.9e-38 129.8 0.0 2.5e-37 128.5 0.0 1.7 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain PS-DH PF14765.6 EGG17554.1 - 7.3e-36 123.9 0.0 1.2e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Chal_sti_synt_C PF02797.15 EGG17554.1 - 1.8e-20 73.5 0.0 5.2e-20 72.0 0.0 1.9 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain KAsynt_C_assoc PF16197.5 EGG17554.1 - 3.4e-18 66.1 0.1 1.4e-17 64.1 0.1 2.2 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EGG17554.1 - 7.1e-18 65.2 0.0 3.3e-17 63.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG17554.1 - 4.7e-12 46.1 0.0 1.3e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FAE1_CUT1_RppA PF08392.12 EGG17554.1 - 2.9e-10 39.9 0.1 6e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 EGG17554.1 - 9.7e-08 32.1 0.2 6.2e-07 29.5 0.0 2.5 3 0 0 3 3 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ADH_zinc_N_2 PF13602.6 EGG17554.1 - 1.7e-07 32.4 0.0 9.7e-07 29.9 0.0 2.4 3 0 0 3 3 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EGG17554.1 - 3.6e-07 29.9 0.0 4e-06 26.4 0.0 2.9 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 EGG17554.1 - 5e-07 30.0 0.0 1.2e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGG17554.1 - 6.8e-06 25.6 0.2 2.1e-05 24.0 0.2 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 EGG17554.1 - 7.2e-06 25.5 0.1 2.4e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGG17554.1 - 1.9e-05 25.3 0.0 8.6e-05 23.2 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG17554.1 - 7.6e-05 23.3 0.0 0.00036 21.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 EGG17554.1 - 8e-05 22.5 0.0 0.00021 21.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 EGG17554.1 - 9.4e-05 22.2 0.0 0.00042 20.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EGG17554.1 - 0.00012 21.8 0.1 0.00034 20.2 0.1 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III PF08545.10 EGG17554.1 - 0.005 16.7 1.7 0.038 13.8 0.0 3.1 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Coiled PF05710.12 EGG17554.1 - 0.51 11.2 6.8 3.1 8.7 0.2 3.5 2 0 0 2 2 2 0 Coiled coil NDUF_B7 PF05676.13 EGG17555.1 - 0.00023 20.8 2.9 0.00023 20.8 2.9 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) SUIM_assoc PF16619.5 EGG17555.1 - 1.2 9.2 15.0 2.3 8.3 15.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CHCH PF06747.13 EGG17555.1 - 2.2 8.5 11.9 1.3 9.2 0.2 3.3 4 0 0 4 4 4 0 CHCH domain Cmc1 PF08583.10 EGG17555.1 - 5.8 7.0 11.0 0.041 13.9 2.4 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like IPPT PF01715.17 EGG17556.1 - 1.7e-23 83.7 0.0 2.6e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 EGG17556.1 - 3.6e-06 26.5 0.0 5.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase Zeta_toxin PF06414.12 EGG17556.1 - 0.0001 21.6 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 EGG17556.1 - 0.035 14.5 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EGG17556.1 - 0.073 13.2 0.0 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 EGG17556.1 - 0.099 12.2 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain IstB_IS21 PF01695.17 EGG17556.1 - 0.2 11.4 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein HSBP1 PF06825.12 EGG17557.1 - 1.4e-24 85.7 7.6 1.9e-24 85.3 7.6 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF2130 PF09903.9 EGG17557.1 - 0.0079 15.5 3.4 0.0094 15.2 3.4 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2130) Prefoldin_2 PF01920.20 EGG17557.1 - 0.018 15.0 0.5 0.018 15.0 0.5 1.6 1 1 0 1 1 1 0 Prefoldin subunit XhlA PF10779.9 EGG17557.1 - 0.022 15.0 1.0 0.059 13.6 0.4 1.9 1 1 1 2 2 2 0 Haemolysin XhlA GAS PF13851.6 EGG17557.1 - 0.023 14.1 4.2 0.026 13.9 4.2 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PhoU PF01895.19 EGG17557.1 - 0.031 14.7 0.6 0.042 14.3 0.6 1.1 1 0 0 1 1 1 0 PhoU domain BLOC1_2 PF10046.9 EGG17557.1 - 0.035 14.4 2.7 0.063 13.6 1.5 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EGG17557.1 - 0.036 14.1 1.4 0.045 13.8 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EGG17557.1 - 0.037 14.4 1.6 0.079 13.4 0.8 1.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Cullin_Nedd8 PF10557.9 EGG17557.1 - 0.044 13.8 0.5 0.11 12.5 0.5 1.8 1 1 0 1 1 1 0 Cullin protein neddylation domain Fzo_mitofusin PF04799.13 EGG17557.1 - 0.061 12.9 3.6 0.069 12.7 3.6 1.1 1 0 0 1 1 1 0 fzo-like conserved region EST1 PF10374.9 EGG17557.1 - 0.074 13.7 3.1 0.12 13.1 3.1 1.4 1 1 0 1 1 1 0 Telomerase activating protein Est1 YvrJ PF12841.7 EGG17557.1 - 0.092 12.3 0.9 0.48 10.0 0.1 2.1 2 0 0 2 2 2 0 YvrJ protein family DUF935 PF06074.12 EGG17557.1 - 0.11 11.3 4.3 0.12 11.1 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DUF4675 PF15720.5 EGG17557.1 - 0.12 12.2 2.9 0.14 12.0 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4675) SPOUT_MTase_2 PF14419.6 EGG17557.1 - 0.18 11.2 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP DUF327 PF03885.13 EGG17557.1 - 0.19 11.7 5.8 0.041 13.8 2.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF327) DUF4094 PF13334.6 EGG17557.1 - 0.31 11.5 3.1 0.27 11.7 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) DUF4407 PF14362.6 EGG17557.1 - 0.7 9.2 3.7 0.79 9.0 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Allexi_40kDa PF05549.11 EGG17557.1 - 0.89 9.0 5.6 0.99 8.9 5.6 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein RRM_1 PF00076.22 EGG17558.1 - 2.8e-51 171.2 2.8 9.4e-15 54.2 0.4 5.8 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 EGG17558.1 - 0.0013 18.7 0.0 0.11 12.5 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 EGG17558.1 - 0.041 13.7 3.4 0.24 11.2 0.3 3.5 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain Peptidase_M28 PF04389.17 EGG17559.1 - 3.9e-22 78.9 0.0 5.7e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGG17559.1 - 1.9e-09 37.5 0.1 4.1e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PA PF02225.22 EGG17559.1 - 0.00059 19.8 2.0 0.00075 19.5 0.3 2.0 2 0 0 2 2 2 1 PA domain Synaptobrevin PF00957.21 EGG17559.1 - 0.029 14.1 0.8 0.069 13.0 0.8 1.6 1 0 0 1 1 1 0 Synaptobrevin ETRAMP PF09716.10 EGG17559.1 - 0.032 14.3 0.2 0.061 13.4 0.2 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3671 PF12420.8 EGG17559.1 - 0.16 12.1 0.2 0.28 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function RecU PF03838.14 EGG17559.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Recombination protein U Sigma_reg_N PF13800.6 EGG17559.1 - 0.17 12.2 0.3 0.53 10.6 0.3 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF3328 PF11807.8 EGG17559.1 - 0.22 11.3 0.9 0.46 10.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) TFIID_30kDa PF03540.13 EGG17560.1 - 1.6e-16 59.9 0.0 2.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit K_channel_TID PF07941.11 EGG17560.1 - 0.0036 17.7 0.8 0.0062 17.0 0.8 1.4 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain SLX9 PF15341.6 EGG17560.1 - 1.3 9.5 12.2 2.2 8.7 12.2 1.3 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 Carb_kinase PF01256.17 EGG17562.1 - 9.1e-49 166.1 0.0 1.8e-48 165.2 0.0 1.5 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 EGG17562.1 - 0.013 14.9 0.1 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Vma12 PF11712.8 EGG17563.1 - 1.6e-10 41.2 0.2 2.9e-10 40.4 0.0 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DEAD PF00270.29 EGG17564.1 - 4.6e-42 143.8 1.5 5.6e-42 143.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG17564.1 - 0.0041 17.5 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain VPS11_C PF12451.8 EGG17564.1 - 6.6 7.1 7.9 26 5.1 7.9 2.1 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal ketoacyl-synt PF00109.26 EGG17566.1 - 7.7e-09 35.5 0.0 8.1e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG17567.1 - 2.2e-47 162.1 0.0 3.5e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 EGG17567.1 - 1.8e-45 155.5 0.0 3.8e-45 154.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGG17567.1 - 1.6e-36 124.9 0.1 5e-36 123.3 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGG17567.1 - 3.2e-28 98.9 2.9 1.5e-27 96.6 0.0 3.1 4 0 0 4 4 4 1 KR domain PS-DH PF14765.6 EGG17567.1 - 4e-26 92.0 0.0 6.3e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGG17567.1 - 1.8e-15 57.4 0.1 7.2e-15 55.4 0.1 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 EGG17567.1 - 4.9e-07 29.6 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGG17567.1 - 1.1e-05 25.7 0.0 3.3e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGG17567.1 - 0.00026 20.4 0.0 0.00063 19.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Sacchrp_dh_NADP PF03435.18 EGG17567.1 - 0.0043 17.3 0.0 0.024 14.9 0.0 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain COX2_TM PF02790.15 EGG17568.1 - 0.082 13.1 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DUF3458 PF11940.8 EGG17568.1 - 0.14 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Ig-like fold Ank_2 PF12796.7 EGG17568.1 - 0.34 11.5 5.4 0.55 10.9 0.1 3.1 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) CLU PF13236.6 EGG17569.1 - 5.8e-62 209.4 0.0 1e-61 208.6 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria TOM20_plant PF06552.12 EGG17569.1 - 0.00019 21.2 0.2 0.00049 19.9 0.2 1.6 1 0 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 eIF3_p135 PF12807.7 EGG17569.1 - 0.00022 21.3 0.0 0.00022 21.3 0.0 2.9 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 HALZ PF02183.18 EGG17570.1 - 0.16 12.2 19.7 0.36 11.1 1.1 4.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper Prenyltransf PF01255.19 EGG17571.1 - 5.9e-70 235.3 0.1 5.9e-70 235.3 0.1 1.8 2 1 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Death PF00531.22 EGG17571.1 - 0.011 15.9 1.9 0.018 15.2 0.9 1.9 2 0 0 2 2 2 0 Death domain DUF3439 PF11921.8 EGG17571.1 - 0.56 10.2 5.4 1.2 9.1 4.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGG17571.1 - 0.7 9.9 10.7 1.1 9.3 10.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Lyase_1 PF00206.20 EGG17572.1 - 3.1e-48 164.8 0.0 4.4e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 EGG17572.1 - 6.7e-47 158.3 0.4 3.4e-46 156.1 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal AAA_22 PF13401.6 EGG17573.1 - 1.3e-05 25.4 0.0 4e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 EGG17573.1 - 0.00013 21.5 0.0 0.00049 19.5 0.0 1.9 1 1 0 1 1 1 1 Bacterial TniB protein AAA_14 PF13173.6 EGG17573.1 - 0.0013 18.8 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGG17573.1 - 0.0041 17.6 0.0 0.0068 16.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGG17573.1 - 0.009 15.9 0.1 0.58 10.0 0.0 2.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EGG17573.1 - 0.013 15.8 1.0 1.4 9.2 0.1 2.3 1 1 0 2 2 2 0 AAA ATPase domain Eno-Rase_FAD_bd PF07055.12 EGG17573.1 - 0.018 15.4 0.0 0.072 13.5 0.0 2.0 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Arc_PepC_II PF06847.11 EGG17574.1 - 1 9.9 3.2 51 4.5 0.3 3.4 3 1 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II AIRC PF00731.20 EGG17575.1 - 3.2e-61 205.3 0.9 6.6e-61 204.2 0.9 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EGG17575.1 - 2e-52 177.2 0.1 5e-52 175.9 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain SAICAR_synt PF01259.18 EGG17575.1 - 3e-49 167.9 0.0 4.9e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 SAICAR synthetase PurK_C PF17769.1 EGG17575.1 - 1.4e-13 50.2 0.9 3.4e-13 49.1 0.9 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 EGG17575.1 - 2.3e-05 24.0 0.0 5.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 EGG17575.1 - 0.0033 17.2 0.0 0.0083 15.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Dala_Dala_lig_C PF07478.13 EGG17575.1 - 0.023 14.2 0.1 0.12 11.9 0.0 2.2 2 1 0 2 2 2 0 D-ala D-ala ligase C-terminus F420_oxidored PF03807.17 EGG17575.1 - 0.047 14.3 0.0 0.83 10.3 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGG17575.1 - 0.092 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PALP PF00291.25 EGG17575.1 - 0.16 11.4 1.4 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Aconitase PF00330.20 EGG17576.1 - 5.9e-152 506.9 0.0 9.8e-152 506.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGG17576.1 - 1.6e-44 151.4 0.0 3.1e-44 150.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Fz PF01392.22 EGG17577.1 - 8.2e-05 23.2 9.8 0.00015 22.4 9.8 1.5 1 0 0 1 1 1 1 Fz domain Ependymin PF00811.18 EGG17577.1 - 0.00035 20.8 1.5 0.001 19.4 0.4 2.0 1 1 1 2 2 2 1 Ependymin VioE PF18234.1 EGG17577.1 - 0.026 14.7 0.1 0.052 13.7 0.1 1.4 1 1 0 1 1 1 0 Violacein biosynthetic enzyme VioE TrkH PF02386.16 EGG17578.1 - 1e-61 209.0 26.5 1e-58 199.1 22.1 2.7 2 0 0 2 2 2 2 Cation transport protein FAM176 PF14851.6 EGG17578.1 - 9.7 5.8 11.6 16 5.1 3.5 4.0 4 0 0 4 4 4 0 FAM176 family Profilin PF00235.19 EGG17580.1 - 0.00087 19.6 0.0 0.001 19.4 0.0 1.2 1 0 0 1 1 1 1 Profilin HSP70 PF00012.20 EGG17581.1 - 2.9e-90 303.2 15.9 2.9e-90 303.2 15.9 3.3 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EGG17581.1 - 0.0028 16.5 0.9 0.0053 15.6 0.1 1.9 2 1 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 EGG17581.1 - 0.0066 15.7 4.6 0.32 10.2 0.1 2.7 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Lectin_N PF03954.14 EGG17581.1 - 2.2 8.0 6.2 2.5 7.9 2.2 2.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 EGG17581.1 - 5.6 7.0 10.9 13 5.8 5.2 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) PP28 PF10252.9 EGG17582.1 - 3.6e-10 40.1 19.6 3.6e-10 40.1 19.6 3.0 2 2 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 Y_phosphatase PF00102.27 EGG17584.1 - 5.4e-80 268.3 1.2 6.8e-80 268.0 1.2 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGG17584.1 - 1.1e-06 28.4 0.2 4.2e-06 26.6 0.1 2.0 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGG17584.1 - 0.00024 21.1 0.0 0.0022 18.0 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EGG17584.1 - 0.00068 19.8 0.4 0.0032 17.6 0.0 2.2 2 1 0 2 2 2 1 Inositol hexakisphosphate RAP1 PF07218.11 EGG17584.1 - 0.0014 17.0 2.3 0.002 16.5 2.3 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) adh_short PF00106.25 EGG17585.1 - 5.7e-43 146.6 0.0 8.8e-41 139.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG17585.1 - 7.9e-27 94.3 0.0 1.3e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG17585.1 - 6.3e-13 49.0 0.0 1.1e-12 48.2 0.0 1.4 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EGG17585.1 - 0.00028 20.2 0.0 0.00056 19.3 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EGG17585.1 - 0.0037 16.8 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EGG17585.1 - 0.0058 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 EGG17585.1 - 0.011 14.8 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGG17585.1 - 0.037 13.9 0.0 9.4 6.1 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H-binding EGF_2 PF07974.13 EGG17587.1 - 0.00039 20.7 5.7 0.00039 20.7 5.7 1.9 2 0 0 2 2 2 1 EGF-like domain TMEM154 PF15102.6 EGG17587.1 - 1.6 8.6 4.4 0.47 10.3 0.8 1.9 2 0 0 2 2 2 0 TMEM154 protein family RYDR_ITPR PF01365.21 EGG17588.1 - 9.6e-35 119.8 11.7 1.1e-26 93.5 0.5 5.8 5 1 1 6 6 6 2 RIH domain RIH_assoc PF08454.11 EGG17588.1 - 4.2e-18 65.1 5.9 4.2e-18 65.1 5.9 5.1 5 0 0 5 5 5 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 EGG17588.1 - 4.1e-15 55.6 0.0 5.5e-14 51.9 0.0 2.5 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Ion_trans PF00520.31 EGG17588.1 - 5.6e-06 25.8 26.1 5.6e-06 25.8 26.1 2.5 3 0 0 3 3 3 1 Ion transport protein TolA_bind_tri PF16331.5 EGG17588.1 - 0.46 10.6 4.6 0.34 11.0 0.4 2.9 2 0 0 2 2 2 0 TolA binding protein trimerisation Peptidase_C1 PF00112.23 EGG17589.1 - 1.7e-61 208.1 7.8 2.1e-61 207.8 7.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 EGG17589.1 - 4.3e-12 45.7 0.3 8.7e-12 44.7 0.3 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 EGG17589.1 - 0.0012 17.7 2.2 0.44 9.3 0.5 2.1 2 0 0 2 2 2 2 Peptidase C1-like family EGF_2 PF07974.13 EGG17590.1 - 0.00013 22.3 15.7 0.00027 21.2 15.7 1.6 1 0 0 1 1 1 1 EGF-like domain DUF3844 PF12955.7 EGG17590.1 - 0.00081 19.5 1.7 0.0024 18.0 1.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EB PF01683.18 EGG17590.1 - 0.0078 16.5 1.1 0.017 15.4 1.1 1.5 1 0 0 1 1 1 1 EB module hEGF PF12661.7 EGG17590.1 - 0.013 16.1 10.8 0.036 14.7 10.8 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 EGG17590.1 - 0.016 15.3 3.3 0.041 13.9 3.3 1.7 1 0 0 1 1 1 0 Tenascin EGF domain I-EGF_1 PF18372.1 EGG17590.1 - 0.059 13.5 8.0 0.13 12.4 8.0 1.5 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 EGG17590.1 - 0.11 12.8 10.6 0.28 11.5 10.6 1.7 1 0 0 1 1 1 0 EGF-like domain Replicase PF03090.17 EGG17590.1 - 0.15 11.9 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Replicase family EGF_CA PF07645.15 EGG17590.1 - 0.16 12.2 10.3 0.41 10.9 10.3 1.7 1 0 0 1 1 1 0 Calcium-binding EGF domain RIC1 PF07064.13 EGG17591.1 - 3.7e-59 200.2 0.0 7.2e-59 199.2 0.0 1.4 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 EGG17591.1 - 0.0014 18.9 0.1 3.1 8.2 0.1 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Gelsolin PF00626.22 EGG17594.1 - 3.1e-47 158.3 0.0 7.3e-11 41.8 0.0 5.7 5 0 0 5 5 5 5 Gelsolin repeat PH PF00169.29 EGG17594.1 - 1.4e-18 67.3 3.1 1.5e-08 35.1 0.1 3.8 3 0 0 3 3 3 3 PH domain VHP PF02209.19 EGG17594.1 - 9.1e-12 44.8 0.1 2.3e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 Villin headpiece domain DUF1899 PF08953.11 EGG17594.1 - 1.2e-09 37.9 0.1 4.6e-09 36.0 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 EGG17594.1 - 1.8e-08 34.9 2.0 2.3e-05 25.1 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat PH_13 PF16652.5 EGG17594.1 - 5.8e-05 23.0 3.7 0.074 12.9 1.3 3.5 3 0 0 3 3 3 2 Pleckstrin homology domain PH_11 PF15413.6 EGG17594.1 - 0.00025 21.4 2.4 0.068 13.6 0.7 3.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 EGG17594.1 - 0.002 18.5 2.0 0.12 12.7 0.2 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain Tyrosinase PF00264.20 EGG17594.1 - 0.012 15.9 3.4 0.2 11.9 3.8 2.5 1 1 0 2 2 2 0 Common central domain of tyrosinase PAC4 PF16093.5 EGG17594.1 - 0.022 14.9 0.1 13 6.0 0.0 4.0 4 0 0 4 4 4 0 Proteasome assembly chaperone 4 PH_6 PF15406.6 EGG17594.1 - 0.1 12.9 0.3 23 5.3 0.0 3.3 3 0 0 3 3 3 0 Pleckstrin homology domain PP_kinase_N PF13089.6 EGG17594.1 - 1.1 9.6 4.1 3.9 7.8 3.7 2.2 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain Atg8 PF02991.16 EGG17595.1 - 1.2e-42 144.3 0.2 1.4e-42 144.1 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EGG17595.1 - 2.2e-07 31.2 0.0 2.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 CAP PF00188.26 EGG17597.1 - 1.5e-41 142.2 19.3 1.1e-17 65.0 2.1 4.0 4 0 0 4 4 4 3 Cysteine-rich secretory protein family NPR3 PF03666.13 EGG17597.1 - 0.055 12.3 4.6 0.092 11.5 4.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neugrin PF06413.11 EGG17597.1 - 2 8.3 8.6 4.8 7.1 8.6 1.6 1 0 0 1 1 1 0 Neugrin CAP PF00188.26 EGG17598.1 - 4.1e-15 56.7 0.1 5.2e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CPP1-like PF11833.8 EGG17599.1 - 1.1 8.8 4.9 1.5 8.4 3.5 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Colicin_V PF02674.16 EGG17599.1 - 7.5 6.5 20.3 0.33 10.9 11.2 3.3 3 1 1 4 4 4 0 Colicin V production protein Phage_holin_3_3 PF16083.5 EGG17600.1 - 0.0083 16.2 6.0 1 9.5 0.6 2.9 2 0 0 2 2 2 2 LydA holin phage, holin superfamily III YjcB PF15940.5 EGG17600.1 - 0.23 11.6 1.9 13 6.0 0.2 2.9 2 0 0 2 2 2 0 Family of unknown function SelP_N PF04592.14 EGG17600.1 - 1.4 8.2 14.8 0.073 12.5 3.0 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Spec3 PF15795.5 EGG17600.1 - 1.9 9.1 14.7 3.5 8.2 0.8 4.2 3 0 0 3 3 3 0 Ectodermal ciliogenesis protein Acyl-CoA_dh_1 PF00441.24 EGG17601.1 - 4.6e-46 156.7 1.1 7.4e-46 156.1 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGG17601.1 - 3.3e-28 98.6 0.1 9e-28 97.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGG17601.1 - 1.2e-26 92.8 0.0 2.1e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGG17601.1 - 2.8e-20 72.9 0.0 5.1e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EGG17601.1 - 0.02 14.5 0.2 0.062 13.0 0.2 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Ank_2 PF12796.7 EGG17602.1 - 2.7e-09 37.5 1.7 0.0018 18.8 0.0 3.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17602.1 - 2e-06 28.2 0.6 0.028 15.0 0.0 4.9 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17602.1 - 0.0002 21.5 0.0 1.2e+02 3.7 0.0 6.0 5 0 0 5 5 5 0 Ankyrin repeat SANT_DAMP1_like PF16282.5 EGG17603.1 - 1.8e-27 95.3 5.1 1.8e-27 95.3 5.1 2.6 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 EGG17603.1 - 8.9e-05 22.4 6.7 8.9e-05 22.4 6.7 3.6 2 1 1 3 3 3 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.31 EGG17603.1 - 0.0022 18.1 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG17603.1 - 0.0074 16.5 1.2 0.023 14.9 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain CPSase_L_D2 PF02786.17 EGG17604.1 - 5e-76 254.9 0.1 9e-76 254.0 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGG17604.1 - 1.8e-45 154.0 0.1 5.9e-45 152.3 0.1 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGG17604.1 - 3.6e-35 120.3 0.0 1.1e-34 118.7 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGG17604.1 - 2.9e-15 55.8 4.4 1.6e-14 53.5 1.8 3.2 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGG17604.1 - 8.4e-12 45.0 0.0 1.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGG17604.1 - 4.3e-11 42.7 0.2 1.3e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EGG17604.1 - 1.3e-05 24.9 2.3 0.001 18.9 0.1 2.9 2 1 1 3 3 3 1 Biotin-lipoyl like RnfC_N PF13375.6 EGG17604.1 - 5.1e-05 23.2 0.3 0.0004 20.3 0.1 2.5 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 EGG17604.1 - 6.8e-05 23.5 0.5 0.28 11.9 0.1 3.4 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 EGG17604.1 - 9.2e-05 22.5 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EGG17604.1 - 0.00072 19.4 0.0 0.0017 18.2 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.19 EGG17604.1 - 0.0093 15.9 0.1 0.025 14.5 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein RimK PF08443.11 EGG17604.1 - 0.013 15.2 0.0 0.057 13.0 0.0 2.0 1 1 0 1 1 1 0 RimK-like ATP-grasp domain NQRA PF05896.11 EGG17604.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_4 PF13535.6 EGG17604.1 - 0.074 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain CBS PF00571.28 EGG17605.1 - 1.8e-25 89.1 2.7 6.1e-08 33.0 0.2 4.3 4 0 0 4 4 4 4 CBS domain GCP_N_terminal PF17681.1 EGG17607.1 - 1.1e-61 209.2 0.1 3.3e-61 207.6 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF1474 PF07342.11 EGG17607.1 - 0.24 12.0 1.1 3.3 8.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) GCP_C_terminal PF04130.13 EGG17608.1 - 2.2e-45 155.5 10.8 2.4e-45 155.3 10.8 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal ATP-synt_D PF01813.17 EGG17608.1 - 0.077 12.8 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 ATP synthase subunit D WD40 PF00400.32 EGG17609.1 - 7.6e-06 26.6 4.6 1.6e-05 25.6 0.1 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat CRT10 PF08728.10 EGG17609.1 - 0.00047 18.5 17.1 0.0091 14.2 0.3 3.6 2 2 0 2 2 2 2 CRT10 ANAPC4_WD40 PF12894.7 EGG17609.1 - 0.0065 16.8 0.1 0.023 15.0 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PS_Dcarbxylase PF02666.15 EGG17610.1 - 1.7e-62 210.5 0.0 2.8e-62 209.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Ank_2 PF12796.7 EGG17610.1 - 8.8e-05 23.0 0.1 0.058 14.0 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG17610.1 - 0.027 15.0 0.1 41 5.2 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeat PRKCSH_1 PF13015.6 EGG17610.1 - 0.08 12.6 2.1 0.24 11.1 0.2 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein TruB_N PF01509.18 EGG17611.1 - 2.8 8.3 8.1 9.6 6.6 7.2 2.3 1 1 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) HAD_2 PF13419.6 EGG17612.1 - 6.8e-11 42.6 2.0 7.9e-11 42.4 0.2 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG17612.1 - 1.7e-07 31.7 0.1 3.6e-06 27.4 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGG17612.1 - 0.00012 22.1 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 EGG17612.1 - 0.031 14.1 0.0 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Acid Phosphatase Csm1_N PF18504.1 EGG17613.1 - 0.0043 17.4 0.6 0.018 15.4 0.6 2.0 1 0 0 1 1 1 1 Csm1 N-terminal domain DUF4472 PF14739.6 EGG17613.1 - 0.016 15.9 1.2 0.016 15.9 1.2 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4472) TSC22 PF01166.18 EGG17613.1 - 0.016 15.5 1.2 9.2 6.7 0.0 3.0 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 EGG17613.1 - 0.028 14.5 1.0 2.3 8.3 0.0 2.4 1 1 1 2 2 2 0 bZIP transcription factor DUF4621 PF15414.6 EGG17613.1 - 0.047 12.6 1.3 0.075 11.9 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) SseC PF04888.12 EGG17613.1 - 0.084 12.5 1.0 0.16 11.6 1.0 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ABC_tran_CTD PF16326.5 EGG17613.1 - 0.09 13.0 1.7 0.25 11.6 1.7 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain Sec2p PF06428.11 EGG17613.1 - 0.11 12.5 4.8 0.058 13.4 1.4 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Macoilin PF09726.9 EGG17613.1 - 0.71 8.4 17.9 1.6 7.2 17.9 1.4 1 1 0 1 1 1 0 Macoilin family RhoGEF PF00621.20 EGG17614.1 - 8.4e-37 127.2 8.8 1.9e-36 126.0 8.8 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 EGG17614.1 - 0.00086 19.8 1.9 0.0013 19.2 0.3 2.1 2 0 0 2 2 2 1 PH domain PH_5 PF15405.6 EGG17614.1 - 0.001 19.2 2.0 0.012 15.7 0.1 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_10 PF15411.6 EGG17614.1 - 0.013 15.7 0.1 0.045 14.0 0.1 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain MADF_DNA_bdg PF10545.9 EGG17614.1 - 0.048 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like IQ_SEC7_PH PF16453.5 EGG17614.1 - 0.056 13.4 0.6 0.15 12.0 0.6 1.8 1 0 0 1 1 1 0 PH domain DUF3720 PF12517.8 EGG17615.1 - 0.022 15.7 0.2 0.041 14.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) Dicty_CTDC PF00526.18 EGG17617.1 - 9.2e-28 95.8 304.4 4.4e-07 29.7 9.1 22.0 19 7 1 20 20 20 13 Dictyostelium (slime mold) repeat Vps51 PF08700.11 EGG17618.1 - 4.4e-26 90.8 2.9 8.6e-26 89.9 1.1 2.6 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 EGG17618.1 - 7.6e-15 55.2 2.8 7.6e-15 55.2 2.8 2.9 2 1 1 3 3 3 1 Exocyst complex component Sec5 Dor1 PF04124.12 EGG17618.1 - 1.5e-11 43.6 5.5 1.5e-11 43.6 5.5 2.8 3 0 0 3 3 3 1 Dor1-like family Vps54_N PF10475.9 EGG17618.1 - 4.9e-07 29.3 6.2 4.9e-07 29.3 6.2 2.0 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 EGG17618.1 - 6.3e-05 23.1 3.9 0.00089 19.4 0.4 2.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 GED PF02212.18 EGG17618.1 - 0.0015 18.7 0.7 2 8.7 0.3 3.3 2 0 0 2 2 2 2 Dynamin GTPase effector domain DUF2116 PF09889.9 EGG17618.1 - 0.032 14.2 0.4 0.3 11.1 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Exonuc_VII_S PF02609.16 EGG17618.1 - 0.035 14.2 0.2 0.22 11.6 0.1 2.5 2 0 0 2 2 2 0 Exonuclease VII small subunit COG5 PF10392.9 EGG17618.1 - 0.11 12.6 17.2 0.027 14.6 2.7 4.2 4 2 0 4 4 4 0 Golgi transport complex subunit 5 RPW8 PF05659.11 EGG17618.1 - 0.57 9.9 5.8 0.16 11.6 1.4 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Phage_connect_1 PF05135.13 EGG17618.1 - 0.81 10.2 7.8 2.2 8.9 2.1 4.0 4 0 0 4 4 4 0 Phage gp6-like head-tail connector protein UPF0184 PF03670.13 EGG17618.1 - 1.1 9.6 4.2 3.6 8.0 0.4 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) DUF4504 PF14953.6 EGG17619.1 - 6.4e-09 35.6 11.7 1.7e-07 30.9 9.6 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4504) Arf PF00025.21 EGG17620.1 - 5.3e-58 195.3 0.7 6.5e-58 195.0 0.7 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG17620.1 - 5.2e-13 49.3 0.0 7.5e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG17620.1 - 1.1e-11 44.6 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGG17620.1 - 2.4e-09 36.9 0.1 3.1e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGG17620.1 - 1.3e-05 24.5 0.2 0.0015 17.7 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EGG17620.1 - 3.2e-05 24.0 0.1 4.3e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGG17620.1 - 0.00021 20.7 0.1 0.00026 20.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EGG17620.1 - 0.017 15.4 0.1 0.027 14.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGG17620.1 - 0.028 14.0 0.2 0.16 11.6 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 EGG17620.1 - 0.034 14.2 0.1 0.061 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGG17620.1 - 0.13 12.8 0.1 0.18 12.3 0.1 1.4 1 1 0 1 1 1 0 ABC transporter SelK_SelG PF10961.8 EGG17621.1 - 0.0054 17.3 2.5 0.0072 16.9 2.5 1.2 1 0 0 1 1 1 1 Selenoprotein SelK_SelG GRP PF07172.11 EGG17621.1 - 0.075 13.7 11.9 0.088 13.5 11.9 1.2 1 0 0 1 1 1 0 Glycine rich protein family Cellulose_synt PF03552.14 EGG17622.1 - 0.52 8.7 2.5 0.76 8.2 2.5 1.2 1 0 0 1 1 1 0 Cellulose synthase Ribosomal_L17 PF01196.19 EGG17623.1 - 6.6e-29 100.7 0.4 6.6e-29 100.7 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 Rsd_AlgQ PF04353.13 EGG17625.1 - 0.0027 17.7 2.6 0.69 9.9 0.1 2.7 2 0 0 2 2 2 2 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF948 PF06103.11 EGG17625.1 - 0.0034 17.6 4.4 0.15 12.3 0.1 3.3 2 2 1 3 3 3 1 Bacterial protein of unknown function (DUF948) ING PF12998.7 EGG17625.1 - 0.019 15.6 7.1 0.73 10.5 0.6 2.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4381 PF14316.6 EGG17625.1 - 0.028 14.7 0.1 0.089 13.0 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) RSS_P20 PF11757.8 EGG17625.1 - 0.029 14.8 5.7 0.086 13.3 0.1 2.9 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain TMF_TATA_bd PF12325.8 EGG17625.1 - 0.059 13.6 5.2 0.5 10.6 0.1 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Bap31_Bap29_C PF18035.1 EGG17625.1 - 0.069 13.2 1.6 0.18 11.8 1.6 1.7 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Col_cuticle_N PF01484.17 EGG17625.1 - 0.1 12.6 0.1 1.2 9.2 0.0 2.9 2 1 1 3 3 3 0 Nematode cuticle collagen N-terminal domain Fib_alpha PF08702.10 EGG17625.1 - 0.44 10.7 10.8 11 6.2 0.1 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Dynamin_M PF01031.20 EGG17625.1 - 0.55 9.4 9.1 0.33 10.1 1.2 3.1 2 2 1 3 3 3 0 Dynamin central region Occludin_ELL PF07303.13 EGG17625.1 - 0.62 10.8 5.9 6.6 7.5 0.1 2.7 3 0 0 3 3 2 0 Occludin homology domain AI-2E_transport PF01594.16 EGG17625.1 - 0.7 9.0 5.0 2.2 7.3 0.2 2.4 2 0 0 2 2 2 0 AI-2E family transporter Syntaxin_2 PF14523.6 EGG17625.1 - 1.6 9.1 18.2 0.14 12.6 1.3 4.2 2 2 3 5 5 5 0 Syntaxin-like protein DUF848 PF05852.11 EGG17625.1 - 2.1 8.4 5.7 0.67 10.1 0.7 2.4 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) BLOC1_2 PF10046.9 EGG17625.1 - 3.5 8.0 12.1 1.5 9.1 0.6 3.9 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec34 PF04136.15 EGG17625.1 - 5.4 6.9 12.4 1.3 8.9 0.2 2.9 3 0 0 3 3 3 0 Sec34-like family GrpE PF01025.19 EGG17625.1 - 8.5 6.0 8.7 0.72 9.5 0.5 2.6 3 0 0 3 3 3 0 GrpE F-box PF00646.33 EGG17626.1 - 7.1e-07 29.0 0.1 1.5e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGG17626.1 - 6.2e-06 26.0 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like SpoIIIAH PF12685.7 EGG17626.1 - 0.004 17.0 4.5 0.0077 16.1 4.5 1.4 1 0 0 1 1 1 1 SpoIIIAH-like protein CCDC106 PF15794.5 EGG17626.1 - 0.0045 16.7 7.0 0.0075 16.0 7.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 Neur_chan_memb PF02932.16 EGG17626.1 - 0.0084 16.2 2.9 0.018 15.1 2.9 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region GUN4 PF05419.12 EGG17626.1 - 0.013 15.6 0.2 0.024 14.7 0.2 1.5 1 0 0 1 1 1 0 GUN4-like Peptidase_S77 PF03420.13 EGG17626.1 - 0.043 13.5 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Prohead core protein serine protease Zip PF02535.22 EGG17626.1 - 0.049 12.8 0.5 0.066 12.4 0.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MLANA PF14991.6 EGG17626.1 - 0.058 13.7 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein melan-A DUF2149 PF09919.9 EGG17626.1 - 0.13 12.6 0.1 0.36 11.1 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Shisa PF13908.6 EGG17626.1 - 0.38 11.0 6.3 0.68 10.1 6.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 EGG17626.1 - 5.3 8.1 7.9 16 6.6 7.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Imm7 PF15585.6 EGG17627.1 - 2.1 8.7 7.1 0.71 10.2 0.2 2.6 1 1 0 2 2 2 0 Immunity protein 7 NCE101 PF11654.8 EGG17627.1 - 2.9 7.7 7.0 5.4 6.8 2.0 2.6 1 1 1 2 2 2 0 Non-classical export protein 1 EF-hand_6 PF13405.6 EGG17628.1 - 5.4e-17 60.2 0.7 8.7e-07 28.4 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGG17628.1 - 9.8e-17 61.2 0.0 4.1e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGG17628.1 - 3.1e-15 54.5 2.5 1.5e-06 27.4 0.1 3.9 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.6 EGG17628.1 - 4.9e-11 41.6 0.8 0.00036 19.9 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGG17628.1 - 5.6e-10 38.9 2.1 0.0021 17.8 0.0 3.4 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 EGG17628.1 - 2.1e-05 24.7 0.0 0.11 12.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain DUF2666 PF10869.8 EGG17628.1 - 0.0074 16.5 0.0 1.6 8.9 0.1 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF2666) UPF0154 PF03672.13 EGG17628.1 - 0.017 15.1 0.0 3 8.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.9 EGG17628.1 - 0.14 12.5 0.0 21 5.4 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MMM1 PF10296.9 EGG17629.1 - 5.5e-06 25.7 0.6 1.5e-05 24.2 0.2 1.8 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 SMP_LBD PF17047.5 EGG17629.1 - 0.018 14.5 0.1 0.054 12.9 0.0 1.7 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain tRNA-synt_2b PF00587.25 EGG17630.1 - 1.2e-42 146.0 0.1 1.8e-42 145.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGG17630.1 - 5.4e-06 26.5 0.0 2e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain SpoU_methylase PF00588.19 EGG17633.1 - 7e-29 100.8 0.0 1.4e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family zf-ISL3 PF14690.6 EGG17633.1 - 0.082 13.6 0.4 0.22 12.2 0.4 1.8 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Ogr_Delta PF04606.12 EGG17633.1 - 0.46 10.5 7.7 6.6 6.8 0.2 3.5 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger M_domain PF12938.7 EGG17633.1 - 3.5 7.4 17.3 0.61 9.8 13.2 1.7 2 0 0 2 2 2 0 M domain of GW182 E_Pc_C PF06752.12 EGG17633.1 - 6 6.9 13.0 16 5.5 13.0 1.7 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus AA_permease_2 PF13520.6 EGG17635.1 - 1e-35 123.4 39.9 1.3e-35 123.0 39.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGG17635.1 - 1.7e-17 63.2 34.6 3.9e-17 62.0 32.8 2.4 1 1 0 1 1 1 1 Amino acid permease Ni_hydr_CYTB PF01292.20 EGG17635.1 - 0.3 10.7 0.0 0.3 10.7 0.0 3.4 2 2 0 2 2 2 0 Prokaryotic cytochrome b561 ECH_1 PF00378.20 EGG17636.1 - 1.1e-78 264.0 0.1 1.4e-78 263.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGG17636.1 - 8.2e-36 124.2 1.0 3.6e-35 122.1 1.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAC PF01849.18 EGG17637.1 - 2.6e-17 62.5 0.3 1.1e-16 60.5 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA_3 PF09288.10 EGG17637.1 - 0.012 15.4 0.1 0.027 14.3 0.1 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain MPDZ_u10 PF16667.5 EGG17637.1 - 1.3 10.0 4.9 1.2 10.1 2.6 1.9 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein Alba PF01918.21 EGG17638.1 - 1.7e-09 37.4 0.1 3e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Alba EnY2 PF10163.9 EGG17639.1 - 5.8e-31 106.7 0.9 7.2e-31 106.4 0.9 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF5066 PF16728.5 EGG17639.1 - 0.015 14.6 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) SAP PF02037.27 EGG17639.1 - 0.091 12.5 1.9 0.58 10.0 0.0 3.1 4 0 0 4 4 4 0 SAP domain Trans_reg_C PF00486.28 EGG17639.1 - 0.097 12.8 0.1 1 9.5 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal SRI PF08236.11 EGG17639.1 - 0.11 12.7 1.7 0.18 12.0 0.6 2.0 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain DUF4218 PF13960.6 EGG17639.1 - 0.11 12.1 0.1 0.87 9.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4218) DUF4470 PF14737.6 EGG17640.1 - 1.6e-05 25.0 0.0 3.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_12 PF13424.6 EGG17640.1 - 4.8e-05 23.6 0.7 0.0055 17.0 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG17640.1 - 0.0004 20.1 2.2 0.35 10.8 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG17640.1 - 0.00042 19.9 1.7 0.0005 19.7 0.3 1.9 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 EGG17640.1 - 0.0022 18.0 5.5 0.12 12.6 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG17640.1 - 0.0033 17.9 2.7 0.0041 17.6 0.6 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat PMBR PF09373.10 EGG17640.1 - 0.14 12.3 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat Catalase_C PF18011.1 EGG17640.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases TPR_7 PF13176.6 EGG17640.1 - 0.46 10.6 1.7 28 5.0 0.2 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat LIM PF00412.22 EGG17641.1 - 1.3e-13 50.9 9.8 1.5e-13 50.7 9.8 1.1 1 0 0 1 1 1 1 LIM domain zf-C3HC4_5 PF17121.5 EGG17641.1 - 0.26 11.2 6.3 0.15 12.0 3.0 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YacG PF03884.14 EGG17641.1 - 0.78 9.5 6.4 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Zn-ribbon_8 PF09723.10 EGG17641.1 - 2 8.6 8.4 12 6.2 4.7 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-B_box PF00643.24 EGG17641.1 - 2.9 8.1 12.2 3.7 7.8 8.1 2.5 2 1 1 3 3 3 0 B-box zinc finger Prok-RING_1 PF14446.6 EGG17641.1 - 3.9 7.5 15.2 11 6.0 3.9 3.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Nnf1 PF03980.14 EGG17642.1 - 3.5e-17 62.8 1.8 8.1e-17 61.6 1.8 1.7 1 0 0 1 1 1 1 Nnf1 DUF948 PF06103.11 EGG17642.1 - 0.19 12.0 1.3 1.2 9.5 1.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Holin_BhlA PF10960.8 EGG17642.1 - 0.24 11.4 5.4 0.19 11.7 2.7 2.1 2 0 0 2 2 2 0 BhlA holin family 6PF2K PF01591.18 EGG17643.1 - 1e-80 270.2 0.0 1.8e-80 269.5 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGG17643.1 - 1.3e-35 122.9 0.0 2e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sld5 PF05916.11 EGG17643.1 - 2.6e-07 31.1 5.8 6e-07 29.9 2.7 2.7 2 1 0 2 2 2 1 GINS complex protein AAA_33 PF13671.6 EGG17643.1 - 5.1e-05 23.5 0.0 0.00016 21.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AIP3 PF03915.13 EGG17643.1 - 0.0095 15.1 2.5 0.036 13.2 0.1 2.2 2 0 0 2 2 2 1 Actin interacting protein 3 PsbU PF06514.11 EGG17643.1 - 0.022 14.7 0.5 0.28 11.2 0.1 2.9 4 0 0 4 4 4 0 Photosystem II 12 kDa extrinsic protein (PsbU) DUF4750 PF15938.5 EGG17645.1 - 1.9e-13 49.8 0.8 2.2e-13 49.6 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) DEAD PF00270.29 EGG17646.1 - 5e-49 166.4 1.4 8.1e-49 165.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG17646.1 - 2.3e-32 111.6 0.1 4.4e-29 101.1 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGG17646.1 - 0.13 12.5 0.2 0.54 10.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain Zip PF02535.22 EGG17646.1 - 0.45 9.7 0.0 0.45 9.7 0.0 2.7 2 1 0 3 3 3 0 ZIP Zinc transporter MMS1_N PF10433.9 EGG17647.1 - 4.8e-158 526.8 0.0 1.3e-157 525.3 0.0 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGG17647.1 - 1.8e-88 296.9 0.6 2.3e-87 293.3 0.4 2.6 3 0 0 3 3 3 1 CPSF A subunit region XAP5 PF04921.14 EGG17648.1 - 0.073 12.9 0.6 0.11 12.3 0.6 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Proteasome PF00227.26 EGG17649.1 - 1.7e-48 164.6 0.3 1.9e-48 164.4 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit PhoLip_ATPase_N PF16209.5 EGG17651.1 - 5.6e-28 96.4 4.8 2.8e-27 94.2 4.8 2.3 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal PhoLip_ATPase_C PF16212.5 EGG17651.1 - 1.7e-24 87.0 2.9 1.7e-24 87.0 2.9 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 EGG17651.1 - 4.6e-13 49.1 0.0 6.5e-12 45.4 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGG17651.1 - 2.8e-10 40.9 0.8 2.1e-05 24.9 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGG17651.1 - 1.1e-09 38.0 0.0 3e-08 33.4 0.0 3.2 3 1 0 3 3 3 1 E1-E2 ATPase DUF4397 PF14344.6 EGG17651.1 - 1.7e-05 25.6 0.2 1.7e-05 25.6 0.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4397) Hydrolase_3 PF08282.12 EGG17651.1 - 0.021 14.6 0.0 0.021 14.6 0.0 3.3 5 0 0 5 5 5 0 haloacid dehalogenase-like hydrolase Terminase_3C PF17288.2 EGG17651.1 - 0.19 12.1 2.9 0.28 11.6 0.0 2.6 3 0 0 3 3 3 0 Terminase RNAseH like domain DUF4064 PF13273.6 EGG17651.1 - 2.9 8.2 6.3 11 6.4 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Phg_2220_C PF09524.10 EGG17652.1 - 0.018 15.1 0.1 0.055 13.5 0.1 1.9 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) DNA_pol_A_exo1 PF01612.20 EGG17652.1 - 0.048 13.4 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 3'-5' exonuclease Fusion_F0 PF13044.6 EGG17652.1 - 0.048 12.3 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus NTF2 PF02136.20 EGG17653.1 - 1.4e-15 57.9 0.1 1.7e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain MINDY_DUB PF04424.13 EGG17654.1 - 1.5e-27 95.9 0.1 4.6e-27 94.4 0.1 1.9 1 0 0 1 1 1 1 MINDY deubiquitinase cobW PF02492.19 EGG17655.1 - 2.7e-57 193.2 2.4 3.9e-57 192.7 2.4 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGG17655.1 - 2.5e-25 88.2 0.0 5.2e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EGG17655.1 - 0.00022 21.2 1.2 0.2 11.5 0.2 2.6 2 0 0 2 2 2 2 RsgA GTPase MobB PF03205.14 EGG17655.1 - 0.0017 18.3 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 EGG17655.1 - 0.0053 16.7 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 EGG17655.1 - 0.0096 15.0 1.0 0.016 14.2 1.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein TsaE PF02367.17 EGG17655.1 - 0.019 15.0 0.1 0.049 13.6 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 EGG17655.1 - 0.021 13.8 0.5 0.23 10.4 0.0 2.6 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EGG17655.1 - 0.045 14.1 0.1 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Cytomega_UL20A PF05984.12 EGG17655.1 - 0.21 11.9 4.0 0.74 10.1 4.0 1.9 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein FAM199X PF15814.5 EGG17655.1 - 0.93 8.5 7.4 1.4 7.9 7.4 1.2 1 0 0 1 1 1 0 Protein family FAM199X DUF3439 PF11921.8 EGG17655.1 - 6.8 6.7 8.6 13 5.8 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) UPF0020 PF01170.18 EGG17656.1 - 5e-13 49.2 0.0 4.8e-10 39.4 0.0 2.7 2 2 0 2 2 2 2 Putative RNA methylase family UPF0020 COG4 PF08318.12 EGG17656.1 - 0.011 14.8 1.0 0.076 12.1 0.0 2.3 3 0 0 3 3 3 0 COG4 transport protein TetR_C_8 PF14278.6 EGG17656.1 - 0.55 10.4 0.1 0.55 10.4 0.1 2.5 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region Acetyltransf_2 PF00797.17 EGG17657.1 - 1.7e-16 60.8 0.0 2.2e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Acetyltransf_2 PF00797.17 EGG17658.1 - 2.3e-31 109.4 0.1 3.1e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 N-acetyltransferase Fz PF01392.22 EGG17659.1 - 0.00019 22.0 3.3 0.00051 20.6 3.3 1.7 1 0 0 1 1 1 1 Fz domain DUF2649 PF10854.8 EGG17659.1 - 0.0085 16.4 5.9 0.0085 16.4 5.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2649) MARVEL PF01284.23 EGG17659.1 - 0.012 15.6 2.9 0.012 15.6 2.9 2.8 2 0 0 2 2 2 0 Membrane-associating domain DUF4231 PF14015.6 EGG17659.1 - 2 8.9 4.6 6.8 7.2 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Mito_carr PF00153.27 EGG17660.1 - 1.3e-68 227.0 1.5 4.5e-22 77.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Arf PF00025.21 EGG17661.1 - 1.4e-55 187.4 0.2 2.1e-55 186.9 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG17661.1 - 7.4e-13 48.8 0.1 1.5e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG17661.1 - 9.4e-10 38.3 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGG17661.1 - 7.5e-08 32.0 0.1 1.6e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGG17661.1 - 3.3e-07 29.8 1.6 0.00089 18.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EGG17661.1 - 6.4e-07 29.5 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGG17661.1 - 3.7e-05 23.2 0.5 0.00014 21.3 0.5 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MobB PF03205.14 EGG17661.1 - 0.0055 16.6 0.0 0.0086 16.0 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.27 EGG17661.1 - 0.064 12.8 0.2 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 EGG17661.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGG17661.1 - 0.18 12.0 0.2 0.37 11.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EGG17661.1 - 0.45 10.0 3.7 2.7 7.5 3.7 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B FNIP PF05725.12 EGG17662.1 - 0.14 12.4 6.2 4 7.7 0.1 4.0 4 0 0 4 4 4 0 FNIP Repeat CWC25 PF12542.8 EGG17663.1 - 4.6e-15 56.4 2.1 4.6e-15 56.4 2.1 5.0 4 2 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EGG17663.1 - 4.4e-13 49.2 14.4 4.4e-13 49.2 14.4 6.1 4 2 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Cnd1 PF12717.7 EGG17664.1 - 0.45 10.5 6.1 0.1 12.7 0.4 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CDC45 PF02724.14 EGG17665.1 - 0.085 11.1 3.9 0.11 10.8 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 EGG17665.1 - 0.18 11.0 6.8 0.18 11.0 6.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Dicty_CAR PF05462.11 EGG17666.1 - 1.7e-11 43.8 23.5 1.7e-11 43.8 23.5 1.7 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor PH PF00169.29 EGG17667.1 - 6.5e-13 49.1 0.6 6.5e-13 49.1 0.6 1.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EGG17667.1 - 0.00044 20.6 0.7 0.00044 20.6 0.7 3.0 1 1 1 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 EGG17667.1 - 0.0013 19.1 0.0 0.0037 17.6 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain Macoilin PF09726.9 EGG17667.1 - 0.054 12.0 11.6 0.057 12.0 11.6 1.1 1 0 0 1 1 1 0 Macoilin family Tmemb_cc2 PF10267.9 EGG17667.1 - 0.12 11.5 3.1 0.15 11.1 3.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SprA-related PF12118.8 EGG17667.1 - 0.48 9.5 20.0 0.65 9.1 20.0 1.1 1 0 0 1 1 1 0 SprA-related family SMYLE_N PF18615.1 EGG17667.1 - 0.74 9.3 6.6 0.88 9.1 6.6 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain FSA_C PF10479.9 EGG17667.1 - 0.92 7.6 12.8 1.1 7.3 12.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus ABC2_membrane_3 PF12698.7 EGG17668.1 - 4.4e-31 108.3 22.6 7.4e-31 107.5 22.6 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 EGG17668.1 - 7.9e-24 84.7 0.0 1.5e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGG17668.1 - 2.4e-06 27.6 0.8 0.0025 17.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 EGG17668.1 - 6.5e-05 22.4 13.9 6.5e-05 22.4 13.9 2.6 3 0 0 3 3 3 2 ABC-2 type transporter AAA_23 PF13476.6 EGG17668.1 - 0.0055 17.2 0.9 0.0055 17.2 0.9 2.3 2 1 0 2 2 2 1 AAA domain Orthopox_B11R PF07033.11 EGG17668.1 - 0.85 9.5 0.0 0.85 9.5 0.0 3.3 4 0 0 4 4 4 0 Orthopoxvirus B11R protein DUF4131 PF13567.6 EGG17668.1 - 1.6 8.4 3.8 5.7 6.6 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) EphA2_TM PF14575.6 EGG17669.1 - 0.13 13.2 0.1 0.86 10.5 0.1 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ETRAMP PF09716.10 EGG17669.1 - 0.46 10.6 5.2 0.44 10.6 2.4 2.4 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PQQ PF01011.21 EGG17670.1 - 0.007 16.2 0.6 0.5 10.4 0.0 3.6 3 0 0 3 3 3 1 PQQ enzyme repeat DUF4999 PF16390.5 EGG17671.1 - 0.58 10.4 3.7 0.21 11.9 1.2 1.5 1 1 1 2 2 2 0 Domain of unknown function Big_9 PF17963.1 EGG17673.1 - 7.1e-23 81.2 131.5 2.5e-10 41.0 2.3 13.5 14 1 0 14 14 14 8 Bacterial Ig domain Cadherin_4 PF17803.1 EGG17673.1 - 1.4e-09 38.5 107.5 0.028 15.0 0.4 12.5 12 1 0 12 12 12 8 Bacterial cadherin-like domain Cadherin_3 PF16184.5 EGG17673.1 - 6.1e-08 32.7 16.3 0.71 9.9 0.0 9.0 9 1 0 10 10 10 3 Cadherin-like Cadherin_5 PF17892.1 EGG17673.1 - 1.2e-06 28.4 29.9 3.1e-06 27.1 0.8 7.9 8 2 1 9 9 9 2 Cadherin-like domain VWA PF00092.28 EGG17673.1 - 0.00049 20.4 0.9 0.0014 18.9 0.9 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain PRP8_domainIV PF12134.8 EGG17673.1 - 0.11 12.1 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 PRP8 domain IV core Big_9 PF17963.1 EGG17674.1 - 3.9e-19 69.2 145.9 7.7e-10 39.4 17.0 14.0 14 1 0 14 14 14 7 Bacterial Ig domain Cadherin_4 PF17803.1 EGG17674.1 - 1.1e-10 42.0 107.7 6.7e-06 26.6 4.3 12.0 11 1 1 12 12 12 7 Bacterial cadherin-like domain Cadherin_5 PF17892.1 EGG17674.1 - 7.7e-09 35.4 5.3 7.7e-09 35.4 5.3 8.4 8 2 0 8 8 8 2 Cadherin-like domain VWA PF00092.28 EGG17674.1 - 7.8e-07 29.5 0.6 2.3e-06 28.0 0.6 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Cadherin_3 PF16184.5 EGG17674.1 - 0.00024 21.1 26.2 1.5 8.8 0.1 9.8 11 1 0 12 12 12 3 Cadherin-like DUF4595 PF15283.6 EGG17674.1 - 2.9 7.9 8.4 0.7 9.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4595) with porin-like fold Laminin_EGF PF00053.24 EGG17674.1 - 4.2 7.6 17.6 10 6.3 8.5 2.6 1 1 1 2 2 2 0 Laminin EGF domain Myosin_head PF00063.21 EGG17675.1 - 1.1e-200 668.4 15.6 1.6e-200 667.8 15.6 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGG17675.1 - 4.4e-31 108.0 3.6 6.5e-31 107.5 0.3 2.4 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 EGG17675.1 - 0.0001 21.8 0.3 0.0001 21.8 0.3 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif DUF3446 PF11928.8 EGG17675.1 - 0.034 14.5 7.4 0.082 13.2 7.4 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain ATP_bind_2 PF03668.15 EGG17675.1 - 0.075 12.3 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop ATPase protein family AAA_22 PF13401.6 EGG17675.1 - 0.075 13.3 0.1 0.45 10.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EGG17675.1 - 0.088 13.3 0.0 0.37 11.3 0.0 2.1 1 0 0 1 1 1 0 ABC transporter TrwB_AAD_bind PF10412.9 EGG17675.1 - 0.13 11.2 0.7 11 4.8 0.0 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activat PF00158.26 EGG17675.1 - 0.15 11.7 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain LMBR1 PF04791.16 EGG17676.1 - 5.3e-21 75.1 3.4 5.3e-21 75.1 3.4 2.5 2 1 1 3 3 3 2 LMBR1-like membrane protein DUF1980 PF09323.10 EGG17676.1 - 0.31 10.9 0.1 0.31 10.9 0.1 3.4 1 1 0 3 3 3 0 Domain of unknown function (DUF1980) Bunya_G1 PF03557.15 EGG17677.1 - 0.018 13.1 1.0 0.023 12.7 1.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 HSP70 PF00012.20 EGG17678.1 - 0.006 14.8 1.6 0.0064 14.7 1.6 1.0 1 0 0 1 1 1 1 Hsp70 protein Amidase PF01425.21 EGG17678.1 - 0.0088 15.0 0.2 0.0088 15.0 0.2 1.0 1 0 0 1 1 1 1 Amidase TetR_C_8 PF14278.6 EGG17678.1 - 0.0097 16.0 0.4 0.76 9.9 0.1 2.3 1 1 1 2 2 2 2 Transcriptional regulator C-terminal region PLC-beta_C PF08703.10 EGG17678.1 - 0.01 15.8 1.3 0.013 15.5 1.3 1.1 1 0 0 1 1 1 0 PLC-beta C terminal DUF3829 PF12889.7 EGG17678.1 - 0.022 14.2 3.2 0.027 14.0 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) ACP_PD PF04336.12 EGG17678.1 - 0.053 13.9 1.1 1.2 9.5 0.1 2.1 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase DUF1542 PF07564.11 EGG17678.1 - 0.054 13.6 4.0 0.096 12.8 1.5 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) Gelsolin PF00626.22 EGG17679.1 - 7.8e-14 51.3 0.0 8.6e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 Gelsolin repeat Ank_2 PF12796.7 EGG17679.1 - 0.00027 21.5 0.5 0.0016 19.0 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG17679.1 - 0.018 15.7 0.1 7.2 7.3 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17679.1 - 0.035 14.6 0.0 8.2 7.4 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat ABC_membrane PF00664.23 EGG17681.1 - 1.4e-127 425.0 13.7 1.9e-65 221.2 1.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGG17681.1 - 2.9e-67 225.4 9.1 8e-34 117.1 0.0 3.2 4 0 0 4 4 3 2 ABC transporter SMC_N PF02463.19 EGG17681.1 - 1e-13 51.3 0.0 1.8e-05 24.3 0.0 3.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EGG17681.1 - 8.5e-08 31.4 0.7 0.0016 17.3 0.1 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EGG17681.1 - 9e-05 22.4 1.7 0.21 11.5 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 EGG17681.1 - 0.00024 21.4 0.1 0.79 10.0 0.0 3.1 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EGG17681.1 - 0.00032 20.9 4.0 0.24 11.7 0.3 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGG17681.1 - 0.00048 19.8 1.6 0.91 9.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGG17681.1 - 0.0014 17.9 1.6 2.4 7.4 0.1 3.4 3 0 0 3 3 3 2 Zeta toxin DUF815 PF05673.13 EGG17681.1 - 0.0032 16.7 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) G-alpha PF00503.20 EGG17681.1 - 0.0045 16.2 0.0 0.2 10.8 0.0 2.4 2 1 0 2 2 2 1 G-protein alpha subunit Synapsin_N PF10581.9 EGG17681.1 - 0.0076 16.2 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 1 Synapsin N-terminal AAA_16 PF13191.6 EGG17681.1 - 0.0095 16.3 3.3 2.3 8.6 0.5 3.3 2 2 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EGG17681.1 - 0.013 15.1 0.0 3.8 7.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 EGG17681.1 - 0.016 14.8 0.6 2.3 7.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 EGG17681.1 - 0.044 14.0 0.5 13 6.0 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 EGG17681.1 - 0.21 11.6 1.7 39 4.2 0.0 3.9 3 1 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EGG17681.1 - 2.7 7.7 4.5 22 4.7 0.1 3.9 5 0 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system Pkinase PF00069.25 EGG17682.1 - 1.5e-78 263.8 0.6 2e-78 263.4 0.6 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG17682.1 - 8.2e-41 140.0 0.0 1.2e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG17682.1 - 1e-09 38.2 0.0 1.9e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGG17682.1 - 3.6e-06 26.2 0.9 5.2e-06 25.6 0.9 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGG17682.1 - 4.5e-05 22.4 0.0 8.2e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGG17682.1 - 0.00018 21.5 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGG17682.1 - 0.00032 20.4 0.3 0.00075 19.2 0.3 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGG17682.1 - 0.00034 20.0 0.1 0.00059 19.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGG17682.1 - 0.0007 19.2 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_C PF00433.24 EGG17682.1 - 0.0049 17.5 0.7 0.025 15.3 0.7 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain Ammonium_transp PF00909.21 EGG17683.1 - 1.1e-108 363.5 31.2 1.3e-108 363.3 31.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family EF-hand_1 PF00036.32 EGG17684.1 - 3.2e-13 48.2 13.9 0.00039 19.8 0.3 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGG17684.1 - 2.3e-12 45.8 12.0 0.0013 18.4 0.2 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGG17684.1 - 4.8e-12 46.1 8.3 4e-08 33.6 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGG17684.1 - 9.9e-05 22.1 3.1 0.25 11.2 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG17684.1 - 0.0003 20.1 13.9 0.015 14.7 0.2 4.1 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 EGG17684.1 - 0.0028 18.0 1.6 0.5 10.7 0.3 2.7 1 1 2 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 EGG17684.1 - 0.0053 16.7 3.0 0.82 9.6 0.1 2.8 1 1 2 3 3 3 2 Caleosin related protein DUF4411 PF14367.6 EGG17684.1 - 0.044 13.7 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Ras PF00071.22 EGG17685.1 - 1.8e-51 173.9 0.4 2.4e-51 173.6 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG17685.1 - 8.8e-33 113.1 0.1 1.8e-32 112.1 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG17685.1 - 5.9e-15 55.1 0.1 7.8e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG17685.1 - 6.8e-07 28.9 0.3 9.5e-07 28.4 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGG17685.1 - 2.3e-06 27.3 1.8 5.7e-06 26.0 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG17685.1 - 0.00052 20.1 0.0 0.00098 19.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGG17685.1 - 0.0019 17.7 0.1 0.0026 17.2 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit YwhD PF08741.10 EGG17685.1 - 0.02 14.6 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 YwhD family DUF1863 PF08937.11 EGG17685.1 - 0.052 13.9 0.2 0.1 12.9 0.2 1.6 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) BCDHK_Adom3 PF10436.9 EGG17685.1 - 0.06 13.2 1.5 0.11 12.3 1.5 1.6 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase NTPase_1 PF03266.15 EGG17685.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NTPase TerD PF02342.18 EGG17686.1 - 2.3e-69 232.7 0.0 2.9e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 TerD domain Pox_A30L_A26L PF06086.12 EGG17687.1 - 0.13 11.9 0.6 0.22 11.2 0.6 1.5 1 1 0 1 1 1 0 Orthopoxvirus A26L/A30L protein Ank_2 PF12796.7 EGG17688.1 - 2.2e-10 41.0 0.0 0.00027 21.5 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG17688.1 - 8.7e-06 25.7 0.2 28 5.7 0.0 6.4 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 EGG17688.1 - 0.00029 21.3 2.5 5.7 7.6 0.0 5.4 3 1 3 6 6 6 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG17688.1 - 0.019 15.3 0.0 17 5.9 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeats (many copies) HECW1_helix PF18436.1 EGG17688.1 - 0.11 12.6 0.8 10 6.3 0.0 3.6 3 0 0 3 3 3 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 AcetylCoA_hydro PF02550.15 EGG17689.1 - 1.7e-37 129.4 0.0 2.3e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EGG17689.1 - 9.1e-37 126.4 0.0 1.3e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.12 EGG17689.1 - 0.0023 16.9 0.2 0.0053 15.7 0.1 1.5 2 0 0 2 2 2 1 Citrate lyase, alpha subunit (CitF) DUF1794 PF08768.11 EGG17690.1 - 1.2e-37 129.2 0.0 2e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) CDC45 PF02724.14 EGG17692.1 - 0.0021 16.4 15.3 0.0021 16.4 15.3 2.0 3 0 0 3 3 3 1 CDC45-like protein Glyco_transf_49 PF13896.6 EGG17693.1 - 1.1e-48 166.3 7.5 4.7e-40 137.9 5.2 2.7 3 1 1 4 4 4 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 EGG17693.1 - 0.00049 19.9 0.0 0.0015 18.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 EGG17693.1 - 0.035 14.6 0.1 0.1 13.1 0.1 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 Menin PF05053.13 EGG17693.1 - 0.056 11.8 5.1 0.1 10.9 5.1 1.4 1 0 0 1 1 1 0 Menin dsDNA_bind PF01984.20 EGG17693.1 - 1.3 9.4 9.0 9.1 6.6 0.1 2.6 2 0 0 2 2 2 0 Double-stranded DNA-binding domain DUF4611 PF15387.6 EGG17693.1 - 2.2 8.5 5.6 2.7 8.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) YMF19 PF02326.15 EGG17693.1 - 4.9 8.0 8.9 0.33 11.8 0.5 3.0 3 0 0 3 3 3 0 Plant ATP synthase F0 Androgen_recep PF02166.16 EGG17693.1 - 5.6 5.7 6.0 8.4 5.1 6.0 1.1 1 0 0 1 1 1 0 Androgen receptor PIH1_CS PF18201.1 EGG17694.1 - 0.00019 21.8 0.1 0.00085 19.7 0.1 2.2 1 0 0 1 1 1 1 PIH1 CS-like domain Tho1_MOS11_C PF18592.1 EGG17694.1 - 0.044 13.6 9.8 0.053 13.3 1.0 2.8 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain WD40 PF00400.32 EGG17695.1 - 8.7e-16 58.0 8.4 0.00088 20.0 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 EGG17695.1 - 4e-06 26.4 2.5 0.00073 18.9 0.1 3.3 3 1 1 4 4 4 2 WD40-like domain ANAPC4_WD40 PF12894.7 EGG17695.1 - 0.00025 21.3 0.7 0.19 12.1 0.0 3.5 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4485 PF14846.6 EGG17695.1 - 0.42 10.7 5.1 0.12 12.4 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) BBS2_Mid PF14783.6 EGG17695.1 - 3.5 7.7 8.7 5.9 7.0 0.0 3.8 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Aminotran_1_2 PF00155.21 EGG17697.1 - 3.3e-80 270.0 0.0 3.8e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PhyH PF05721.13 EGG17698.1 - 2e-21 77.2 0.0 3.9e-21 76.3 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SLX9 PF15341.6 EGG17699.1 - 6.1e-17 62.3 18.3 6.1e-17 62.3 18.3 2.7 3 0 0 3 3 3 1 Ribosome biogenesis protein SLX9 DUF5409 PF17421.2 EGG17699.1 - 0.23 12.2 3.7 0.74 10.6 3.7 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5409) Med26 PF08711.11 EGG17700.1 - 0.00045 20.2 0.0 0.0014 18.6 0.0 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SWI-SNF_Ssr4 PF08549.10 EGG17700.1 - 1 7.9 38.3 1.7 7.2 38.3 1.4 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) E1-E2_ATPase PF00122.20 EGG17701.1 - 2.9e-49 167.0 3.9 2.9e-49 167.0 3.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGG17701.1 - 2.3e-39 135.8 0.0 4.4e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGG17701.1 - 4.3e-10 39.9 4.4 2.4e-09 37.5 0.5 3.1 3 0 0 3 3 3 1 Heavy-metal-associated domain PALP PF00291.25 EGG17701.1 - 0.11 11.9 0.0 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EGG17701.1 - 0.14 12.6 0.1 0.62 10.5 0.1 2.1 1 0 0 1 1 1 0 CBS domain HAD PF12710.7 EGG17701.1 - 0.22 11.9 0.0 0.43 11.0 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ATP_bind_3 PF01171.20 EGG17702.1 - 2e-18 66.8 0.0 6e-17 62.0 0.0 2.7 3 0 0 3 3 3 1 PP-loop family zn-ribbon_14 PF16503.5 EGG17702.1 - 2.3e-12 46.2 6.5 2.3e-12 46.2 6.5 3.3 4 0 0 4 4 4 1 Zinc-ribbon DUF2616 PF11077.8 EGG17702.1 - 0.066 12.9 0.5 0.066 12.9 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) DUF3439 PF11921.8 EGG17702.1 - 0.64 10.0 8.8 0.38 10.7 6.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CENP-B_dimeris PF09026.10 EGG17703.1 - 0.018 15.4 4.9 0.018 15.4 4.9 2.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain FAM209 PF15206.6 EGG17703.1 - 0.025 14.4 0.1 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 FAM209 family LRR_8 PF13855.6 EGG17703.1 - 0.032 14.0 2.1 0.6 9.9 0.4 3.5 3 1 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 EGG17703.1 - 0.83 9.9 6.4 13 6.2 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 EGG17703.1 - 1.4 9.4 8.0 4.8 7.7 1.4 4.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF4611 PF15387.6 EGG17703.1 - 7.5 6.8 10.7 0.26 11.5 4.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Clathrin_lg_ch PF01086.17 EGG17704.1 - 1.6e-14 54.5 20.1 2.6e-13 50.6 20.1 2.0 1 1 0 1 1 1 1 Clathrin light chain CRT10 PF08728.10 EGG17704.1 - 0.12 10.6 9.4 0.13 10.4 9.4 1.1 1 0 0 1 1 1 0 CRT10 PIN_2 PF10130.9 EGG17704.1 - 0.48 10.7 2.8 0.72 10.1 2.6 1.4 1 1 0 1 1 1 0 PIN domain BCAS2 PF05700.11 EGG17705.1 - 8.9e-58 195.4 12.9 8.9e-58 195.4 12.9 1.3 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF1289 PF06945.13 EGG17706.1 - 5.9e-18 64.4 3.0 9.7e-18 63.7 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) DUF5393 PF17371.2 EGG17706.1 - 0.0021 16.3 0.2 0.0025 16.0 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5393) PRP21_like_P PF12230.8 EGG17706.1 - 0.035 14.0 0.4 0.044 13.6 0.4 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-HC5HC2H PF13771.6 EGG17706.1 - 0.13 12.5 2.0 0.21 11.9 1.7 1.5 1 1 0 1 1 1 0 PHD-like zinc-binding domain SMC_N PF02463.19 EGG17708.1 - 4.9e-24 85.0 4.9 2.1e-23 82.9 4.8 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGG17708.1 - 1.3e-07 31.7 15.5 6.3e-05 22.9 1.4 4.0 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGG17708.1 - 1.1e-05 26.0 50.7 1.1e-05 26.0 50.7 6.6 3 2 2 5 5 5 1 AAA domain AAA_15 PF13175.6 EGG17708.1 - 1.8e-05 24.7 28.8 1.8e-05 24.7 28.8 4.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EGG17708.1 - 5.4e-05 22.9 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SHE3 PF17078.5 EGG17708.1 - 0.0023 17.7 27.9 0.0023 17.7 27.9 5.0 3 2 2 5 5 5 1 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 EGG17708.1 - 0.0034 16.3 28.6 0.0034 16.3 28.6 6.1 3 2 4 7 7 7 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EGG17708.1 - 0.0075 16.3 22.0 0.0075 16.3 22.0 7.1 4 2 3 7 7 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_25 PF13481.6 EGG17708.1 - 0.025 14.2 0.1 0.1 12.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EGG17708.1 - 0.044 13.4 0.0 0.044 13.4 0.0 4.4 4 1 1 5 5 5 0 AAA domain Endotoxin_N PF03945.14 EGG17709.1 - 6.7e-44 150.3 5.9 9.3e-44 149.8 5.9 1.2 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain IF4E PF01652.18 EGG17709.1 - 0.013 15.3 0.1 0.036 13.8 0.1 1.7 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E RICTOR_phospho PF14665.6 EGG17710.1 - 0.0095 16.2 1.5 0.045 14.1 0.1 2.2 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, phosphorylation-site Macoilin PF09726.9 EGG17711.1 - 0.48 8.9 10.7 2.6 6.5 0.6 2.3 2 0 0 2 2 2 0 Macoilin family OrfB_Zn_ribbon PF07282.11 EGG17712.1 - 9.9e-06 25.4 0.0 0.0064 16.4 0.0 3.1 2 0 0 2 2 2 2 Putative transposase DNA-binding domain DUF2992 PF11208.8 EGG17712.1 - 0.57 10.4 0.0 0.57 10.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Rho_N PF07498.12 EGG17712.1 - 0.85 9.6 2.3 5.2 7.1 0.2 2.9 3 0 0 3 3 3 0 Rho termination factor, N-terminal domain PhoLip_ATPase_C PF16212.5 EGG17717.1 - 9.5e-71 238.5 34.4 9.5e-71 238.5 34.4 3.1 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGG17717.1 - 3.9e-18 64.9 2.8 3.9e-18 64.9 2.8 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGG17717.1 - 1.4e-15 57.1 0.0 2.1e-12 47.0 0.0 2.9 2 0 0 2 2 2 2 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGG17717.1 - 1.3e-11 45.2 0.1 1.6e-05 25.3 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGG17717.1 - 2.1e-05 24.1 0.0 2.1e-05 24.1 0.0 3.2 2 2 1 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGG17717.1 - 0.00024 20.9 0.0 0.01 15.6 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Dmrt1 PF12374.8 EGG17717.1 - 3.9 8.0 9.1 26 5.3 4.9 3.0 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 FUN14 PF04930.15 EGG17718.1 - 5.1e-22 78.1 0.8 5.1e-22 78.1 0.8 2.0 2 1 0 2 2 2 1 FUN14 family CbtB PF09489.10 EGG17718.1 - 0.52 10.4 4.1 0.62 10.2 0.1 2.6 2 1 1 3 3 3 0 Probable cobalt transporter subunit (CbtB) DUF150 PF02576.17 EGG17719.1 - 0.012 16.0 1.3 0.36 11.3 0.1 2.6 2 0 0 2 2 2 0 RimP N-terminal domain DUF4611 PF15387.6 EGG17719.1 - 4.6 7.5 6.6 1.7 8.9 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pkinase PF00069.25 EGG17721.1 - 4.4e-65 219.7 0.8 3.6e-64 216.7 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG17721.1 - 7.3e-46 156.5 0.1 1.5e-45 155.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG17721.1 - 0.0013 18.7 0.0 0.0038 17.2 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGG17721.1 - 0.0052 16.2 0.1 0.0099 15.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGG17721.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.7 1 1 0 1 1 1 0 Kinase-like DUF2796 PF10986.8 EGG17721.1 - 3.5 7.6 24.7 0.021 14.8 15.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) NicO PF03824.16 EGG17721.1 - 6.5 6.0 5.5 10 5.4 5.5 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Innate_immun PF12782.7 EGG17721.1 - 8.6 5.8 20.2 15 4.9 20.2 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Homeodomain PF00046.29 EGG17724.1 - 1.5e-21 76.0 3.3 1.5e-11 44.0 0.0 2.7 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 EGG17724.1 - 4.6e-07 29.6 1.3 0.0014 18.5 0.2 3.1 2 0 0 2 2 2 2 Homeobox KN domain HTH_Tnp_ISL3 PF13542.6 EGG17724.1 - 0.0045 16.4 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_1 PF01527.20 EGG17724.1 - 0.12 12.7 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.6 EGG17724.1 - 0.16 11.8 0.0 1 9.2 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain TIMP PF00965.17 EGG17724.1 - 0.27 11.0 5.7 0.51 10.1 5.7 1.3 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase Det1 PF09737.9 EGG17725.1 - 5.6e-111 371.5 12.3 5.6e-111 371.5 12.3 3.6 2 2 0 2 2 2 1 De-etiolated protein 1 Det1 Mucin PF01456.17 EGG17725.1 - 0.46 10.5 63.7 0.91 9.5 36.7 3.5 3 0 0 3 3 3 0 Mucin-like glycoprotein Endotoxin_N PF03945.14 EGG17726.1 - 1.6e-42 145.7 6.5 2.3e-42 145.2 6.5 1.2 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain IF4E PF01652.18 EGG17726.1 - 0.0018 18.1 0.2 0.02 14.7 0.1 2.3 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E tRNA-synt_1e PF01406.19 EGG17726.1 - 0.0067 15.8 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain FAD_binding_4 PF01565.23 EGG17729.1 - 7.9e-23 80.7 0.3 1.3e-22 80.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGG17729.1 - 1.4e-17 63.5 2.7 4.3e-17 61.9 2.7 1.9 1 0 0 1 1 1 1 Berberine and berberine like WVELL PF14043.6 EGG17729.1 - 0.11 12.4 0.0 0.39 10.6 0.0 1.9 1 0 0 1 1 1 0 WVELL protein CBFD_NFYB_HMF PF00808.23 EGG17730.1 - 4e-16 59.0 0.0 7.3e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGG17730.1 - 3.2e-10 40.5 0.1 3.2e-10 40.5 0.1 2.9 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 DUF5453 PF17534.2 EGG17731.1 - 0.013 15.4 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) SIT PF15330.6 EGG17731.1 - 0.27 11.7 1.7 0.37 11.2 1.2 1.5 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Ank_2 PF12796.7 EGG17732.1 - 4e-09 36.9 1.8 0.008 16.7 0.0 4.3 3 2 3 6 6 6 3 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EGG17732.1 - 0.00019 21.3 1.2 0.12 12.3 0.0 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EGG17732.1 - 0.00063 20.0 1.6 3.8 8.4 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EGG17732.1 - 0.002 18.6 4.1 4.6 7.9 0.0 6.0 6 2 1 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG17732.1 - 0.12 12.7 0.1 12 6.3 0.0 3.8 2 2 1 3 3 3 0 Ankyrin repeats (many copies) Lactonase PF10282.9 EGG17733.1 - 1.4e-79 267.9 1.3 3.5e-79 266.5 1.1 1.7 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller IBR PF01485.21 EGG17733.1 - 3.5e-13 49.6 24.3 3.5e-10 40.0 5.5 4.0 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EGG17733.1 - 0.00021 21.6 12.1 0.00021 21.6 12.1 3.9 3 1 0 3 3 3 1 Ring finger domain Arylesterase PF01731.20 EGG17733.1 - 0.001 19.2 0.2 0.41 10.9 0.0 3.5 4 0 0 4 4 4 1 Arylesterase UPF0223 PF05256.12 EGG17733.1 - 0.0028 17.9 0.2 0.01 16.2 0.2 1.9 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0223) zf-RING_UBOX PF13445.6 EGG17733.1 - 0.013 15.5 10.5 0.013 15.5 10.5 3.5 4 0 0 4 4 4 0 RING-type zinc-finger zf-RING_11 PF17123.5 EGG17733.1 - 0.2 11.4 9.1 0.77 9.6 9.1 2.2 1 0 0 1 1 1 0 RING-like zinc finger Tir_receptor_C PF07489.11 EGG17733.1 - 0.3 11.0 10.6 0.67 9.9 10.6 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF3464 PF11947.8 EGG17733.1 - 3.9 7.2 6.5 14 5.4 6.5 1.9 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 LSM PF01423.22 EGG17734.1 - 1.2e-19 69.8 0.0 1.5e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGG17734.1 - 0.017 15.3 0.0 0.025 14.7 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 EGG17734.1 - 0.059 13.5 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Melibiase_2 PF16499.5 EGG17735.1 - 7.4e-104 346.9 3.9 1e-103 346.4 3.9 1.2 1 0 0 1 1 1 1 Alpha galactosidase A DUF393 PF04134.12 EGG17735.1 - 8.6e-26 91.5 0.1 3.7e-25 89.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF393 Melibiase_C PF17801.1 EGG17735.1 - 1.1e-14 54.2 0.0 3.9e-14 52.5 0.0 2.0 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 EGG17735.1 - 1.4e-06 28.4 0.0 3.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 EGG17735.1 - 1.7e-05 23.9 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Melibiase DDE_Tnp_1_7 PF13843.6 EGG17736.1 - 3.8e-27 95.5 2.7 3.8e-27 95.5 2.7 3.7 4 1 0 4 4 4 1 Transposase IS4 GPCR_chapero_1 PF11904.8 EGG17738.1 - 1.7e-52 178.8 1.8 3e-52 178.0 1.8 1.4 1 0 0 1 1 1 1 GPCR-chaperone Ank_4 PF13637.6 EGG17738.1 - 2.1e-06 28.2 0.0 5.1e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG17738.1 - 8e-06 26.4 0.0 4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG17738.1 - 7.4e-05 23.0 0.0 0.00025 21.3 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG17738.1 - 0.00056 20.2 0.1 0.16 12.6 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EGG17738.1 - 0.013 15.9 0.1 0.15 12.6 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat Rif1_N PF12231.8 EGG17739.1 - 1.1e-71 241.9 0.2 1.1e-71 241.9 0.2 1.8 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal CE2_N PF17996.1 EGG17740.1 - 6.2e-15 55.1 0.0 1.1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 EGG17740.1 - 3.4e-14 53.6 0.0 9.8e-14 52.1 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGG17740.1 - 1.3e-06 28.6 0.0 9e-06 25.8 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TFIIE-A_C PF11521.8 EGG17741.1 - 0.13 12.5 0.2 0.21 11.9 0.2 1.2 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha PCO_ADO PF07847.12 EGG17742.1 - 1.3e-26 93.3 4.7 9.5e-25 87.2 2.6 2.9 2 1 0 2 2 2 1 PCO_ADO UbiA PF01040.18 EGG17742.1 - 1.2e-17 64.1 10.5 1.6e-17 63.7 10.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF5325 PF17259.2 EGG17742.1 - 4.2 7.3 6.8 1 9.3 0.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5325) LCM PF04072.14 EGG17743.1 - 9.1e-35 120.3 0.1 5.4e-34 117.8 0.0 1.9 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Transglut_core PF01841.19 EGG17744.1 - 1.3e-11 44.9 0.0 2.8e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily LCM PF04072.14 EGG17745.1 - 1.3e-30 106.8 0.3 4.3e-29 101.8 0.0 2.7 1 1 1 2 2 2 1 Leucine carboxyl methyltransferase Scaffolding_pro PF11418.8 EGG17745.1 - 0.69 10.5 7.0 0.97 10.0 3.2 2.6 2 0 0 2 2 2 0 Phi29 scaffolding protein WH1 PF00568.23 EGG17749.1 - 1.9 8.5 4.6 0.79 9.7 0.4 2.5 4 0 0 4 4 4 0 WH1 domain HrpE PF06188.12 EGG17750.1 - 0.14 12.1 0.1 10 6.0 0.0 2.3 2 0 0 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E Clat_adaptor_s PF01217.20 EGG17751.1 - 1.2e-44 151.7 3.1 1.4e-44 151.5 3.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DHHC PF01529.20 EGG17752.1 - 5.3e-38 130.2 9.6 9.1e-38 129.4 9.6 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Rer1 PF03248.13 EGG17752.1 - 0.0012 18.7 0.2 0.0023 17.7 0.2 1.4 1 0 0 1 1 1 1 Rer1 family Nucleoside_tran PF01733.18 EGG17752.1 - 0.0082 15.6 1.4 0.013 14.9 1.4 1.3 1 0 0 1 1 1 1 Nucleoside transporter TAS2R PF05296.13 EGG17752.1 - 0.02 14.0 2.3 0.033 13.3 2.3 1.3 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) FAM176 PF14851.6 EGG17752.1 - 0.031 14.0 0.0 0.031 14.0 0.0 3.4 3 1 0 3 3 3 0 FAM176 family DUF4834 PF16118.5 EGG17752.1 - 0.039 14.9 0.4 0.039 14.9 0.4 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4834) Peptidase_M56 PF05569.11 EGG17752.1 - 0.061 12.5 1.8 0.073 12.2 1.1 1.4 1 1 0 1 1 1 0 BlaR1 peptidase M56 Peroxin-13_N PF04088.13 EGG17752.1 - 0.088 13.1 1.2 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Peroxin 13, N-terminal region CSG2 PF16965.5 EGG17752.1 - 1.9 7.4 10.5 0.089 11.7 1.8 2.2 1 1 1 2 2 2 0 Ceramide synthase regulator Stn1 PF10451.9 EGG17753.1 - 0.011 14.7 1.1 0.022 13.7 1.1 1.4 1 0 0 1 1 1 0 Telomere regulation protein Stn1 FlgI PF02119.16 EGG17753.1 - 0.023 13.6 0.1 0.057 12.3 0.1 1.6 1 0 0 1 1 1 0 Flagellar P-ring protein ProQ PF04352.13 EGG17753.1 - 0.099 12.5 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 ProQ/FINO family Sporozoite_P67 PF05642.11 EGG17753.1 - 2.5 6.1 14.0 0.023 12.8 3.0 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Mucin PF01456.17 EGG17753.1 - 4.4 7.3 18.1 6.6 6.7 2.8 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein NST1 PF13945.6 EGG17753.1 - 6.6 6.8 18.0 0.6 10.2 9.7 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator Connexin PF00029.19 EGG17755.1 - 0.0075 16.0 0.7 0.0075 16.0 0.7 3.7 2 1 0 2 2 2 1 Connexin Activator-TraM PF11657.8 EGG17755.1 - 1.1 9.1 5.4 2.3 8.1 5.4 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM Spore_YhcN_YlaJ PF09580.10 EGG17755.1 - 4.5 7.3 0.0 4.5 7.3 0.0 3.8 3 2 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Pur_ac_phosph_N PF16656.5 EGG17756.1 - 1.5e-19 70.4 0.8 4.8e-19 68.7 0.8 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DUF3430 PF11912.8 EGG17756.1 - 0.00044 20.4 5.0 0.00044 20.4 5.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3430) PAP2_3 PF14378.6 EGG17758.1 - 5.1e-14 52.4 7.5 5.1e-14 52.4 7.5 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EGG17758.1 - 1.8e-07 31.0 6.4 1.8e-07 31.0 6.4 2.2 2 0 0 2 2 2 1 PAP2 superfamily DUF1700 PF08006.11 EGG17758.1 - 0.14 11.7 2.3 0.29 10.6 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Glyco_hydro_3 PF00933.21 EGG17759.1 - 2.9e-65 220.8 0.0 3.9e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EGG17759.1 - 1.2e-45 156.0 0.0 2e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EGG17759.1 - 2e-13 50.2 0.1 3.6e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Histone PF00125.24 EGG17760.1 - 2.1e-17 63.7 8.9 2.6e-17 63.4 8.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGG17760.1 - 0.00032 20.9 0.3 0.00032 20.9 0.3 2.4 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 EGG17760.1 - 0.018 15.2 0.3 0.043 14.0 0.3 1.7 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF1180 PF06679.12 EGG17760.1 - 0.068 13.6 1.8 0.079 13.4 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CENP-S PF15630.6 EGG17760.1 - 0.09 13.2 0.3 0.21 12.0 0.3 1.6 1 0 0 1 1 1 0 CENP-S protein Mucin PF01456.17 EGG17760.1 - 8.1 6.4 13.9 14 5.7 13.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DLIC PF05783.11 EGG17761.1 - 9.8e-100 334.6 6.3 2e-98 330.3 6.3 2.0 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) MCPVI PF02993.14 EGG17761.1 - 0.0024 17.7 0.8 0.0047 16.8 0.8 1.4 1 0 0 1 1 1 1 Minor capsid protein VI Roc PF08477.13 EGG17761.1 - 0.0047 17.1 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF4481 PF14800.6 EGG17761.1 - 0.093 12.2 0.1 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) Lipase_3 PF01764.25 EGG17762.1 - 1.2e-20 73.8 1.8 2.3e-20 72.9 0.0 2.4 3 0 0 3 3 3 1 Lipase (class 3) Hydrolase_4 PF12146.8 EGG17762.1 - 1.1e-05 24.9 0.0 0.00071 18.9 0.0 2.6 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Esterase PF00756.20 EGG17762.1 - 0.0076 15.9 0.2 0.058 13.0 0.0 2.2 2 0 0 2 2 2 1 Putative esterase SUIM_assoc PF16619.5 EGG17762.1 - 0.023 14.7 15.9 0.027 14.5 10.7 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PGAP1 PF07819.13 EGG17762.1 - 0.026 14.3 5.4 0.08 12.6 0.0 3.2 3 0 0 3 3 3 0 PGAP1-like protein Androgen_recep PF02166.16 EGG17762.1 - 0.056 12.3 5.9 0.088 11.6 5.9 1.3 1 0 0 1 1 1 0 Androgen receptor Abhydrolase_6 PF12697.7 EGG17762.1 - 0.059 14.0 0.0 0.088 13.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1350 PF07082.11 EGG17762.1 - 0.062 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) Abhydrolase_1 PF00561.20 EGG17762.1 - 0.34 10.5 0.0 0.34 10.5 0.0 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF4770 PF15994.5 EGG17762.1 - 0.58 10.4 8.9 1.8 8.8 8.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) YceD PF02620.17 EGG17762.1 - 0.98 9.6 3.7 0.74 9.9 0.3 2.4 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD TFIIA PF03153.13 EGG17762.1 - 9.3 6.1 34.7 0.12 12.4 23.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rpb8 PF03870.15 EGG17763.1 - 7e-43 146.2 0.2 1.2e-42 145.4 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EGG17763.1 - 2.9e-05 24.1 0.0 0.0018 18.3 0.0 2.1 1 1 0 1 1 1 1 DNA-directed RNA polymerase, subunit G Hexapep PF00132.24 EGG17764.1 - 1.3e-12 46.9 3.3 4e-05 23.2 0.0 4.4 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Syntaxin_2 PF14523.6 EGG17764.1 - 9e-08 32.4 7.4 9e-08 32.4 7.4 2.4 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EGG17764.1 - 1.4e-05 25.0 0.8 2.8e-05 24.0 0.8 1.5 1 0 0 1 1 1 1 SNARE domain Hexapep_2 PF14602.6 EGG17764.1 - 9.6e-05 22.1 3.4 0.009 15.8 1.0 3.1 1 1 1 2 2 2 1 Hexapeptide repeat of succinyl-transferase LAP1C PF05609.12 EGG17764.1 - 0.11 11.6 6.4 0.015 14.5 2.1 1.6 1 1 1 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) CD34_antigen PF06365.12 EGG17764.1 - 0.11 12.0 3.6 0.27 10.8 3.6 1.6 1 0 0 1 1 1 0 CD34/Podocalyxin family Synaptobrevin PF00957.21 EGG17764.1 - 0.83 9.5 5.2 0.5 10.2 2.8 1.9 2 0 0 2 2 2 0 Synaptobrevin MFS_1 PF07690.16 EGG17765.1 - 9.1e-40 136.7 27.1 1.7e-35 122.6 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEMspv1-c74-12 PF11044.8 EGG17765.1 - 0.007 16.3 0.8 0.033 14.2 0.1 2.6 2 0 0 2 2 2 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein MFS_3 PF05977.13 EGG17765.1 - 0.2 10.0 9.1 0.6 8.4 2.0 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Acetyltransf_1 PF00583.25 EGG17766.1 - 1.2e-07 32.0 0.0 0.00046 20.4 0.0 3.8 3 1 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG17766.1 - 0.00015 22.1 0.0 0.0082 16.6 0.0 3.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG17766.1 - 0.001 19.0 0.2 0.06 13.3 0.0 3.4 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGG17766.1 - 0.004 16.7 0.4 0.063 12.7 0.0 2.8 2 1 1 3 3 3 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EGG17766.1 - 0.004 17.2 0.0 0.073 13.2 0.0 2.5 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EGG17766.1 - 0.036 14.1 0.0 0.095 12.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MPC PF03650.13 EGG17767.1 - 1.1e-20 73.8 0.9 1.2e-20 73.6 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MPC PF03650.13 EGG17768.1 - 3.6e-17 62.5 0.1 4.5e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Amino_oxidase PF01593.24 EGG17769.1 - 1.3e-21 77.5 0.1 5e-21 75.5 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGG17769.1 - 4.9e-17 61.9 0.6 9.2e-17 61.0 0.1 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG17769.1 - 1.5e-10 41.2 1.1 5.6e-08 32.8 0.6 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGG17769.1 - 5.9e-07 28.9 0.4 9e-07 28.3 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EGG17769.1 - 3.2e-06 27.6 0.5 2e-05 25.1 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGG17769.1 - 8.3e-05 22.0 0.9 0.00029 20.2 0.7 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGG17769.1 - 0.00041 19.8 1.3 0.00061 19.2 1.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG17769.1 - 0.00057 18.7 0.5 0.00083 18.2 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EGG17769.1 - 0.0024 17.1 0.4 0.0039 16.5 0.4 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EGG17769.1 - 0.0046 16.3 1.0 0.007 15.6 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EGG17769.1 - 0.0047 16.1 1.2 0.011 14.8 0.6 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGG17769.1 - 0.012 14.9 0.2 0.022 14.0 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EGG17769.1 - 0.012 14.1 0.0 0.017 13.6 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like MCRA PF06100.11 EGG17769.1 - 0.019 13.8 0.9 0.076 11.8 0.9 1.9 1 1 0 1 1 1 0 MCRA family AlaDh_PNT_C PF01262.21 EGG17769.1 - 0.02 14.2 0.2 0.03 13.6 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EGG17769.1 - 0.069 13.1 0.3 2 8.4 0.2 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EGG17769.1 - 0.094 12.6 0.7 0.16 11.8 0.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 EGG17769.1 - 0.18 10.6 0.4 0.32 9.8 0.4 1.4 1 0 0 1 1 1 0 Tryptophan halogenase CMAS PF02353.20 EGG17770.1 - 3.8e-87 292.0 0.1 4.9e-87 291.7 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EGG17770.1 - 1.6e-10 41.5 0.0 3.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG17770.1 - 2e-10 40.7 0.0 3.5e-10 40.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG17770.1 - 1e-09 38.9 0.0 2.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG17770.1 - 2.1e-07 30.9 0.0 3.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG17770.1 - 2.5e-07 31.3 0.0 5.9e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG17770.1 - 0.00083 18.9 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 EGG17770.1 - 0.0018 19.3 0.1 0.011 16.7 0.0 2.4 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGG17770.1 - 0.0041 16.4 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 EGG17770.1 - 0.0082 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 EGG17770.1 - 0.0092 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase DOT1 PF08123.13 EGG17770.1 - 0.01 15.4 0.0 0.037 13.6 0.0 1.9 2 0 0 2 2 2 0 Histone methylation protein DOT1 RrnaAD PF00398.20 EGG17770.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.15 EGG17770.1 - 0.013 15.1 0.0 0.037 13.7 0.0 1.8 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Spermine_synth PF01564.17 EGG17770.1 - 0.029 13.8 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Spermine/spermidine synthase domain Methyltransf_18 PF12847.7 EGG17770.1 - 0.048 13.6 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGG17770.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPK_catalytic PF04263.16 EGG17771.1 - 2.6e-30 105.0 0.0 3.9e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EGG17771.1 - 1.2e-16 60.1 3.1 2.3e-16 59.3 0.2 2.4 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain P53_TAD PF08563.11 EGG17771.1 - 4.5 6.9 5.7 0.42 10.2 0.6 1.9 2 0 0 2 2 2 0 P53 transactivation motif Glyco_hydro_47 PF01532.20 EGG17772.1 - 1.3e-132 442.9 5.4 1.6e-132 442.7 5.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 EGG17772.1 - 0.92 9.0 5.7 13 5.2 0.2 3.7 2 1 2 4 4 4 0 Glycosyl hydrolase family 76 PI3_PI4_kinase PF00454.27 EGG17773.1 - 5.5e-42 144.3 0.7 5e-30 105.1 0.4 2.7 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGG17773.1 - 6.3e-23 81.1 0.2 1.8e-22 79.6 0.2 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) SUIM_assoc PF16619.5 EGG17773.1 - 0.054 13.6 12.9 0.15 12.1 2.2 3.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF4805 PF16063.5 EGG17773.1 - 0.092 12.1 6.6 0.21 10.9 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) TFIIA PF03153.13 EGG17773.1 - 4 7.3 13.0 2.1 8.2 4.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nop PF01798.18 EGG17774.1 - 1.8e-65 220.7 0.2 1.8e-65 220.7 0.2 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EGG17774.1 - 8.1e-28 97.8 4.1 8.1e-28 97.8 4.1 2.4 2 0 0 2 2 2 1 Prp31 C terminal domain CDC45 PF02724.14 EGG17774.1 - 0.75 8.0 13.5 1.3 7.2 13.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2408 PF10303.9 EGG17774.1 - 0.95 10.0 8.8 1.8 9.2 7.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4484 PF14831.6 EGG17774.1 - 4 7.4 10.4 7.3 6.6 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Pox_Ag35 PF03286.14 EGG17774.1 - 5.7 6.7 19.1 0.91 9.3 12.2 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SWIM PF04434.17 EGG17775.1 - 5.2e-06 26.0 0.5 9.1e-06 25.2 0.5 1.3 1 0 0 1 1 1 1 SWIM zinc finger SRAP PF02586.14 EGG17776.1 - 1.9e-46 158.4 0.9 2.8e-46 157.8 0.0 1.7 2 0 0 2 2 2 1 SOS response associated peptidase (SRAP) Stevor PF17410.2 EGG17777.1 - 0.0058 16.2 1.1 0.0058 16.2 1.1 2.8 2 2 1 3 3 3 1 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 EGG17777.1 - 0.007 15.8 1.7 0.02 14.3 1.7 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 EGG17777.1 - 0.012 15.4 0.8 0.024 14.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 EGG17777.1 - 0.015 16.2 0.1 0.061 14.2 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Chlam_PMP PF02415.17 EGG17777.1 - 0.019 15.4 1.0 0.019 15.4 1.0 8.7 10 0 0 10 10 10 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Chordopox_A13L PF05961.11 EGG17777.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Adeno_E3_CR2 PF02439.15 EGG17777.1 - 0.061 13.1 3.7 0.19 11.5 3.7 1.9 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TNFR_16_TM PF18422.1 EGG17777.1 - 0.11 12.5 0.7 0.31 11.1 0.7 1.7 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF3951 PF13131.6 EGG17777.1 - 1.2 9.4 10.0 0.4 10.9 2.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) WD40 PF00400.32 EGG17778.1 - 1.3e-36 123.9 6.1 1.8e-06 28.6 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG17778.1 - 9.9e-17 61.0 0.0 0.13 12.6 0.0 5.9 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain CSTF1_dimer PF16699.5 EGG17778.1 - 3.2e-06 26.8 0.1 8.7e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Cleavage stimulation factor subunit 1, dimerisation domain Ge1_WD40 PF16529.5 EGG17778.1 - 5.2e-06 25.7 2.4 0.25 10.2 0.1 3.8 2 2 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EGG17778.1 - 1.9e-05 23.4 0.0 0.0023 16.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 EGG17778.1 - 0.00027 20.9 4.1 0.066 13.1 0.2 3.7 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A HPS3_N PF14761.6 EGG17778.1 - 0.017 14.6 0.1 4.3 6.8 0.0 2.8 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 Syntaxin_2 PF14523.6 EGG17779.1 - 1.7e-12 47.5 3.2 1.7e-12 47.5 3.2 3.4 3 1 0 3 3 3 1 Syntaxin-like protein SNARE PF05739.19 EGG17779.1 - 1.4e-05 25.0 0.2 3.7e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 SNARE domain PNISR PF15996.5 EGG17779.1 - 0.25 11.6 15.0 0.45 10.8 15.0 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DEAD PF00270.29 EGG17780.1 - 5.6e-16 58.8 0.2 2.4e-15 56.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGG17780.1 - 1.9e-11 44.2 0.0 1.9e-11 44.2 0.0 4.0 3 1 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGG17780.1 - 5.2e-06 26.8 0.0 5.2e-06 26.8 0.0 4.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain LRR_4 PF12799.7 EGG17781.1 - 0.46 11.0 4.2 15 6.2 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) PurL_C PF16904.5 EGG17782.1 - 2.8 8.3 6.3 27 5.1 0.1 2.6 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine synthase II C-terminus NOC3p PF07540.11 EGG17783.1 - 9.1e-24 83.7 0.5 9.1e-24 83.7 0.5 3.2 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 EGG17783.1 - 1.5e-19 70.7 0.1 1.5e-19 70.7 0.1 3.2 4 1 0 4 4 4 1 CBF/Mak21 family Tobravirus_2B PF05271.11 EGG17783.1 - 0.1 12.5 1.5 1.5 8.8 0.1 2.9 2 1 0 3 3 3 0 Tobravirus 2B protein DUF5093 PF17011.5 EGG17783.1 - 2.8 8.2 18.6 5.7 7.2 10.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) BTB_2 PF02214.22 EGG17784.1 - 2.2e-16 60.0 0.1 6.7e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Imm5 PF14423.6 EGG17784.1 - 0.075 13.3 0.1 0.075 13.3 0.1 1.8 2 0 0 2 2 2 0 Immunity protein Imm5 BTB PF00651.31 EGG17784.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain RNA_pol_Rpb2_5 PF04567.17 EGG17784.1 - 0.4 11.3 5.0 0.51 10.9 0.0 3.1 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 DUF5009 PF16401.5 EGG17785.1 - 8.6e-09 35.3 2.6 3.1e-08 33.4 1.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5009) EMP24_GP25L PF01105.24 EGG17785.1 - 0.11 12.5 0.1 0.66 9.9 0.1 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2721 PF11026.8 EGG17785.1 - 0.84 9.5 4.1 0.32 10.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Acyl_transf_3 PF01757.22 EGG17785.1 - 1.5 7.8 40.5 1.9e+02 0.9 41.6 2.8 1 1 0 1 1 1 0 Acyltransferase family DUF1774 PF08611.10 EGG17785.1 - 6.1 7.2 8.8 0.34 11.3 0.7 3.1 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) DUF5542 PF17696.1 EGG17785.1 - 6.6 6.9 6.4 1.5 9.0 0.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5542) Cation_ATPase_C PF00689.21 EGG17786.1 - 2e-45 154.7 4.9 2e-45 154.7 4.9 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGG17786.1 - 7e-37 126.7 0.4 7e-37 126.7 0.4 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGG17786.1 - 1.1e-22 79.9 0.0 2e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGG17786.1 - 1.1e-17 65.0 0.1 2.8e-17 63.7 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGG17786.1 - 2.9e-13 49.3 0.0 7.1e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG17786.1 - 0.0003 20.6 0.2 0.084 12.6 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Colicin_im PF03857.13 EGG17786.1 - 0.00056 19.9 0.4 0.0014 18.5 0.4 1.6 1 0 0 1 1 1 1 Colicin immunity protein DUF3792 PF12670.7 EGG17786.1 - 0.1 12.8 0.2 0.1 12.8 0.2 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3792) CLP1_P PF16575.5 EGG17787.1 - 1.2e-43 149.1 0.1 3.5e-43 147.6 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 EGG17787.1 - 0.028 13.7 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 EGG17787.1 - 0.46 10.6 2.4 0.76 9.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain RNA_pol_Rbc25 PF08292.12 EGG17787.1 - 0.52 10.5 4.3 4.1 7.6 0.1 3.0 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 PhoQ_Sensor PF08918.10 EGG17787.1 - 0.99 9.2 5.1 7.3 6.4 0.9 3.2 2 1 0 2 2 2 0 PhoQ Sensor CTU2 PF10288.9 EGG17788.1 - 4.2e-10 39.9 18.6 1.2e-09 38.4 18.6 1.8 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 EGG17788.1 - 0.0064 16.3 1.8 1.6 8.5 0.1 2.8 2 1 0 2 2 2 2 PP-loop family JAKMIP_CC3 PF16034.5 EGG17788.1 - 1.8 8.5 5.0 1.3 8.9 1.2 2.2 2 0 0 2 2 2 0 JAKMIP CC3 domain Sedlin_N PF04628.13 EGG17789.1 - 7.6e-46 155.5 3.3 2.4e-45 153.9 3.3 1.9 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Prefoldin PF02996.17 EGG17789.1 - 3.6e-22 78.5 2.3 3.6e-22 78.5 2.3 2.9 3 0 0 3 3 3 1 Prefoldin subunit Prefoldin_3 PF13758.6 EGG17789.1 - 5.7e-11 42.4 0.8 5.7e-11 42.4 0.8 3.4 3 2 0 3 3 3 1 Prefoldin subunit Sybindin PF04099.12 EGG17789.1 - 6.3e-09 35.9 1.1 3.1e-08 33.7 0.4 2.3 1 1 1 2 2 2 1 Sybindin-like family NPV_P10 PF05531.12 EGG17789.1 - 8.3 7.0 8.9 30 5.1 0.8 3.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SPX PF03105.19 EGG17790.1 - 0.066 13.1 0.1 0.066 13.1 0.1 2.8 2 2 0 2 2 2 0 SPX domain EMC3_TMCO1 PF01956.16 EGG17791.1 - 0.019 14.7 0.7 0.023 14.4 0.7 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like O-antigen_lig PF13425.6 EGG17791.1 - 0.21 10.3 4.3 0.26 10.0 4.3 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SPOUT_MTase PF02590.17 EGG17791.1 - 0.48 10.4 3.6 0.56 10.2 2.6 1.6 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase Ac76 PF05814.11 EGG17791.1 - 2 8.5 5.4 7.5 6.6 0.2 2.2 2 0 0 2 2 2 0 Orf76 (Ac76) Selenoprotein_S PF06936.11 EGG17791.1 - 7.2 6.4 13.1 0.79 9.5 8.7 1.7 1 1 1 2 2 2 0 Selenoprotein S (SelS) DUF2098 PF09871.9 EGG17791.1 - 7.8 6.9 8.4 1.5e+02 2.8 8.4 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Sde2_N_Ubi PF13019.6 EGG17792.1 - 5.8e-25 88.0 2.4 5.8e-25 88.0 2.4 3.5 4 2 0 4 4 4 1 Silencing defective 2 N-terminal ubiquitin domain RNA_GG_bind PF10258.9 EGG17792.1 - 6e-08 32.6 0.2 0.0019 18.2 0.1 2.9 2 0 0 2 2 2 2 PHAX RNA-binding domain DUF3953 PF13129.6 EGG17792.1 - 0.061 13.1 0.8 3.2 7.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) SET PF00856.28 EGG17793.1 - 1.1e-17 65.0 1.3 1.4e-17 64.6 0.1 1.9 2 1 0 2 2 2 1 SET domain SAF PF08666.12 EGG17793.1 - 0.032 14.9 0.0 0.48 11.1 0.0 2.3 2 0 0 2 2 2 0 SAF domain SRP68 PF16969.5 EGG17794.1 - 2.5e-93 314.0 25.1 2.8e-93 313.8 25.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 PrmC_N PF17827.1 EGG17794.1 - 0.38 11.4 3.1 33 5.2 0.0 3.6 4 0 0 4 4 4 0 PrmC N-terminal domain Methyltransf_4 PF02390.17 EGG17794.1 - 0.77 9.2 5.9 0.21 11.0 0.4 2.5 2 0 0 2 2 2 0 Putative methyltransferase zf-CCHC PF00098.23 EGG17795.1 - 8.3e-28 95.2 65.0 4.4e-06 26.5 1.7 7.3 4 1 3 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EGG17795.1 - 0.024 14.4 46.8 0.51 10.1 0.9 7.3 2 2 5 7 7 7 0 Zinc knuckle CENP-B_dimeris PF09026.10 EGG17795.1 - 3 8.3 14.9 0.12 12.8 7.3 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Metallophos PF00149.28 EGG17796.1 - 8.7e-13 49.2 0.7 1.8e-12 48.2 0.7 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FIBP PF05427.11 EGG17798.1 - 3.8e-51 174.5 0.0 5.5e-47 160.8 0.1 2.9 3 0 0 3 3 3 2 Acidic fibroblast growth factor binding (FIBP) DAG_kinase_N PF14513.6 EGG17798.1 - 3.1 8.0 12.4 1 9.6 1.7 2.8 2 1 0 2 2 2 0 Diacylglycerol kinase N-terminus Phosphatase PF15698.5 EGG17799.1 - 0.031 13.4 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphatase MFS_1_like PF12832.7 EGG17800.1 - 3.4e-67 227.0 13.4 6.9e-67 226.0 13.4 1.5 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EGG17800.1 - 2.9e-22 79.1 54.0 3.8e-15 55.7 24.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 EGG17800.1 - 1.7e-12 47.1 28.5 2.8e-07 29.9 11.5 2.3 2 0 0 2 2 2 2 Nucleoside H+ symporter DUF948 PF06103.11 EGG17800.1 - 0.45 10.8 4.0 24 5.3 0.1 4.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) LBP_BPI_CETP_C PF02886.17 EGG17801.1 - 8.6e-07 28.6 0.3 1.7e-06 27.7 0.3 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain NusG_II PF07009.11 EGG17801.1 - 0.071 13.3 2.0 3.4 7.9 0.1 2.4 2 0 0 2 2 2 0 NusG domain II Thg1C PF14413.6 EGG17801.1 - 0.14 12.4 0.3 0.23 11.6 0.3 1.3 1 0 0 1 1 1 0 Thg1 C terminal domain DENN PF02141.21 EGG17802.1 - 3e-43 147.9 2.9 1.1e-36 126.6 2.2 2.7 1 1 1 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 EGG17802.1 - 8.7e-14 52.0 0.1 4.9e-13 49.6 0.1 2.5 1 0 0 1 1 1 1 uDENN domain WD40 PF00400.32 EGG17803.1 - 2e-35 120.2 20.4 2.1e-07 31.5 0.5 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG17803.1 - 1.1e-20 73.7 3.6 0.00072 19.8 0.1 6.7 3 1 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 EGG17803.1 - 0.0046 16.6 0.4 0.084 12.4 0.2 2.8 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 EGG17803.1 - 0.014 15.3 0.1 21 5.2 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 EGG17803.1 - 0.032 14.0 0.0 0.032 14.0 0.0 1.9 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain DUF4073 PF13285.6 EGG17803.1 - 0.037 13.7 0.6 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) Sigma70_ner PF04546.13 EGG17803.1 - 0.054 13.4 8.2 0.11 12.4 8.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region G0-G1_switch_2 PF15103.6 EGG17803.1 - 0.11 12.9 2.2 0.4 11.1 2.2 1.9 1 0 0 1 1 1 0 G0/G1 switch protein 2 Merozoite_SPAM PF07133.11 EGG17803.1 - 2.6 8.0 34.4 0.23 11.5 26.1 2.7 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) PRP38_assoc PF12871.7 EGG17803.1 - 3 8.5 11.0 6.8 7.4 11.0 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term G8 PF10162.9 EGG17805.1 - 4.5e-29 101.0 1.0 1.1e-28 99.7 0.2 2.1 2 0 0 2 2 2 1 G8 domain Pkinase_Tyr PF07714.17 EGG17807.1 - 7.2e-68 228.7 0.0 9.2e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG17807.1 - 1.2e-55 188.8 0.0 1.6e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 EGG17807.1 - 3.3e-13 49.5 0.0 6.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 SH2 domain APH PF01636.23 EGG17807.1 - 0.00031 20.8 0.2 0.0015 18.5 0.0 2.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG17807.1 - 0.00032 19.8 0.0 0.00089 18.3 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Cbl_N2 PF02761.14 EGG17807.1 - 0.012 16.3 0.1 0.03 15.0 0.1 1.7 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain Pkinase_fungal PF17667.1 EGG17807.1 - 0.029 13.2 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 EGG17807.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Zn-ribbon_8 PF09723.10 EGG17808.1 - 0.056 13.6 11.5 5.5 7.2 0.6 4.5 4 0 0 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 EGG17808.1 - 0.091 12.7 21.7 0.049 13.6 4.0 3.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Ribosomal_L37ae PF01780.19 EGG17808.1 - 0.31 11.1 11.5 0.21 11.7 0.6 3.0 3 0 0 3 3 3 0 Ribosomal L37ae protein family OrfB_Zn_ribbon PF07282.11 EGG17808.1 - 0.98 9.4 22.3 0.45 10.5 2.6 3.8 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Mucin PF01456.17 EGG17808.1 - 8 6.5 43.9 0.71 9.9 24.5 3.5 3 0 0 3 3 3 0 Mucin-like glycoprotein AAA PF00004.29 EGG17809.1 - 2.8e-51 173.4 0.1 7e-36 123.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG17809.1 - 1.3e-14 53.7 0.0 4.3e-06 26.4 0.0 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_14 PF13173.6 EGG17809.1 - 1.6e-10 41.1 5.5 0.00021 21.3 0.0 4.4 3 1 1 4 4 3 2 AAA domain AAA_16 PF13191.6 EGG17809.1 - 4.6e-09 36.9 0.0 0.0002 21.8 0.0 3.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EGG17809.1 - 1.2e-08 35.3 0.4 0.012 15.9 0.0 4.8 3 2 1 4 4 4 2 AAA domain AAA_5 PF07728.14 EGG17809.1 - 5.3e-07 29.7 0.0 0.0034 17.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGG17809.1 - 1.4e-06 27.8 0.0 0.00034 19.9 0.1 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 EGG17809.1 - 1.4e-06 28.9 4.1 0.027 15.0 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_2 PF07724.14 EGG17809.1 - 2.2e-06 27.9 0.1 0.0012 19.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGG17809.1 - 2.9e-06 27.1 0.0 0.00039 20.2 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EGG17809.1 - 1.4e-05 25.6 2.1 0.0051 17.3 0.0 3.4 2 1 1 3 3 3 1 ABC transporter Rad17 PF03215.15 EGG17809.1 - 1.6e-05 24.9 0.2 0.0038 17.2 0.0 3.7 3 1 0 3 3 3 1 Rad17 P-loop domain NACHT PF05729.12 EGG17809.1 - 9.2e-05 22.4 0.3 5.8 6.8 0.2 3.8 2 1 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 EGG17809.1 - 0.00011 22.0 0.0 0.022 14.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.13 EGG17809.1 - 0.00012 21.3 0.0 0.027 13.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 EGG17809.1 - 0.00013 21.7 0.0 0.051 13.3 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_7 PF12775.7 EGG17809.1 - 0.00014 21.4 0.0 0.19 11.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 EGG17809.1 - 0.00025 21.4 0.5 0.56 10.6 0.0 3.6 3 1 0 3 3 2 1 RNA helicase Sigma54_activat PF00158.26 EGG17809.1 - 0.00026 20.7 0.0 0.15 11.7 0.0 3.4 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_17 PF13207.6 EGG17809.1 - 0.00034 21.1 0.6 1.5 9.3 0.0 3.4 2 1 0 2 2 2 2 AAA domain ATPase PF06745.13 EGG17809.1 - 0.00099 18.5 4.9 0.16 11.3 0.0 4.0 3 2 1 4 4 4 1 KaiC Mg_chelatase PF01078.21 EGG17809.1 - 0.0029 17.0 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 EGG17809.1 - 0.0048 16.8 3.2 1.8 8.4 0.2 2.9 3 1 0 3 3 2 2 Bacterial dnaA protein AAA_33 PF13671.6 EGG17809.1 - 0.0049 17.0 0.0 0.15 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGG17809.1 - 0.0053 16.5 0.3 0.21 11.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EGG17809.1 - 0.0054 16.6 0.4 1.3 8.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 EGG17809.1 - 0.0073 16.3 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EGG17809.1 - 0.012 14.9 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 EGG17809.1 - 0.017 14.2 0.1 2.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DAP3 PF10236.9 EGG17809.1 - 0.019 14.1 0.0 0.088 12.0 0.0 2.1 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.6 EGG17809.1 - 0.031 13.8 0.1 4.4 6.8 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 EGG17809.1 - 0.038 14.2 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EGG17809.1 - 0.06 13.0 0.1 3 7.4 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zot PF05707.12 EGG17809.1 - 0.065 12.9 0.6 2.8 7.5 0.1 3.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_30 PF13604.6 EGG17809.1 - 0.084 12.6 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGG17809.1 - 0.11 12.8 0.7 10 6.4 0.2 3.4 3 1 0 4 4 3 0 AAA domain Pkinase_Tyr PF07714.17 EGG17810.1 - 5.9e-52 176.5 0.2 1.2e-51 175.5 0.2 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG17810.1 - 1.2e-50 172.3 0.6 4.3e-50 170.5 0.1 2.3 2 0 0 2 2 2 1 Protein kinase domain RGS PF00615.19 EGG17810.1 - 1.5e-12 47.8 8.4 1.5e-12 47.8 8.4 3.1 3 0 0 3 3 3 1 Regulator of G protein signaling domain PPL5 PF18168.1 EGG17810.1 - 3.6 6.8 17.1 0.042 13.1 7.2 2.5 2 0 0 2 2 2 0 Prim-pol family 5 GBP PF02263.19 EGG17813.1 - 3.9e-48 164.0 0.0 3.9e-48 164.0 0.0 2.1 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGG17813.1 - 7.5e-07 28.8 19.4 1.5e-05 24.6 15.7 3.1 2 1 0 2 2 2 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 EGG17813.1 - 0.033 14.3 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGG17813.1 - 0.037 14.1 4.6 0.35 10.9 0.0 3.1 2 1 0 2 2 2 0 Dynamin family EGF_2 PF07974.13 EGG17814.1 - 0.04 14.3 12.1 0.1 13.0 12.1 1.7 1 0 0 1 1 1 0 EGF-like domain EB PF01683.18 EGG17814.1 - 0.11 12.8 5.2 0.28 11.5 5.2 1.7 1 0 0 1 1 1 0 EB module EB PF01683.18 EGG17815.1 - 0.021 15.1 4.7 0.051 13.9 4.7 1.6 1 0 0 1 1 1 0 EB module EGF_2 PF07974.13 EGG17815.1 - 0.051 14.0 10.7 0.14 12.6 10.7 1.7 1 0 0 1 1 1 0 EGF-like domain DUF3042 PF11240.8 EGG17815.1 - 0.99 9.5 2.7 2 8.5 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) LRR_8 PF13855.6 EGG17815.1 - 8.2 6.3 17.7 0.29 10.9 0.8 4.7 3 1 1 4 4 4 0 Leucine rich repeat EGF_2 PF07974.13 EGG17816.1 - 0.032 14.6 8.4 0.084 13.3 8.4 1.7 1 0 0 1 1 1 0 EGF-like domain LRR_8 PF13855.6 EGG17816.1 - 0.49 10.2 17.4 0.024 14.4 1.6 4.5 4 2 1 5 5 5 0 Leucine rich repeat EB PF01683.18 EGG17816.1 - 1.7 9.0 7.9 4 7.8 7.9 1.6 1 0 0 1 1 1 0 EB module EGF_2 PF07974.13 EGG17817.1 - 0.011 16.1 8.9 0.044 14.2 8.9 2.1 1 0 0 1 1 1 0 EGF-like domain EB PF01683.18 EGG17817.1 - 0.043 14.1 6.3 0.13 12.5 6.3 1.8 1 0 0 1 1 1 0 EB module Protocadherin PF08374.11 EGG17817.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protocadherin DDOST_48kD PF03345.14 EGG17818.1 - 3.5e-113 378.6 1.1 4e-113 378.4 1.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Beta-lactamase PF00144.24 EGG17819.1 - 2.3e-38 132.3 0.0 3.4e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase TOM13 PF08219.11 EGG17819.1 - 0.45 10.5 1.9 0.92 9.5 0.4 2.3 2 0 0 2 2 2 0 Outer membrane protein TOM13 Peptidase_C48 PF02902.19 EGG17821.1 - 2.1e-35 122.5 1.7 2.1e-35 122.5 1.7 2.2 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain EGF_2 PF07974.13 EGG17822.1 - 0.026 14.9 8.1 0.067 13.6 8.1 1.7 1 0 0 1 1 1 0 EGF-like domain DUF3042 PF11240.8 EGG17822.1 - 0.05 13.6 1.4 0.62 10.1 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) SHOCT PF09851.9 EGG17823.1 - 3.3e-08 33.0 1.3 5.9e-08 32.2 1.3 1.5 1 0 0 1 1 1 1 Short C-terminal domain DUF3439 PF11921.8 EGG17823.1 - 0.34 10.9 4.1 0.3 11.0 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) EFTUD2 PF16004.5 EGG17824.1 - 3.1e-30 105.3 12.3 5.2e-30 104.5 12.3 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus GTP_EFTU_D2 PF03144.25 EGG17824.1 - 6.2e-09 36.1 0.7 1.3e-08 35.1 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_C PF00679.24 EGG17825.1 - 1.6e-15 56.9 0.0 2.1e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G C-terminus CAP_N PF01213.19 EGG17826.1 - 0.0035 16.9 0.1 0.0035 16.9 0.1 2.0 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal LRR_4 PF12799.7 EGG17827.1 - 0.056 13.9 2.2 0.29 11.6 1.0 2.9 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) MBG_2 PF18676.1 EGG17828.1 - 0.079 13.6 3.3 0.14 12.8 3.3 1.4 1 0 0 1 1 1 0 MBG domain (YGX type) zf-trcl PF13451.6 EGG17829.1 - 1.8e-10 40.6 8.3 2.1e-05 24.3 1.3 2.4 2 0 0 2 2 2 2 Probable zinc-ribbon domain ABC2_membrane_3 PF12698.7 EGG17829.1 - 8.2 5.4 9.6 11 5.0 9.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein MMR_HSR1 PF01926.23 EGG17831.1 - 0.00053 20.0 0.0 0.00084 19.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase His_Phos_2 PF00328.22 EGG17832.1 - 1.3e-20 74.1 0.0 5e-15 55.7 0.0 2.7 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) LRR_4 PF12799.7 EGG17832.1 - 0.13 12.7 1.7 0.91 10.0 0.9 3.0 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) EF-hand_1 PF00036.32 EGG17837.1 - 3.1e-21 73.3 14.2 1.5e-06 27.3 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGG17837.1 - 3.5e-20 70.1 9.9 5.4e-06 25.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGG17837.1 - 1.5e-19 70.2 7.2 1.1e-12 48.2 0.5 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG17837.1 - 1.3e-16 59.3 11.7 3.5e-06 26.3 1.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGG17837.1 - 7.9e-14 51.2 11.0 0.0015 18.4 0.1 4.5 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGG17837.1 - 0.00013 22.2 2.7 0.051 13.9 0.1 3.3 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGG17837.1 - 0.011 16.0 0.4 5.1 7.5 0.0 3.4 3 1 0 3 3 3 0 EF-hand domain Caleosin PF05042.13 EGG17837.1 - 0.022 14.7 2.3 39 4.1 0.0 3.8 1 1 3 4 4 4 0 Caleosin related protein EF-hand_2 PF09068.11 EGG17837.1 - 0.023 14.8 0.1 0.18 11.9 0.1 2.1 2 0 0 2 2 2 0 EF hand DUF4296 PF14129.6 EGG17837.1 - 0.046 14.3 0.0 4.6 7.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) EF-hand_14 PF17959.1 EGG17837.1 - 0.13 12.6 1.3 14 6.1 0.1 2.8 3 0 0 3 3 3 0 EF-hand domain Phage_XkdX PF09693.10 EGG17837.1 - 1.4 9.0 3.8 14 5.8 0.2 2.8 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) tRNA-synt_1e PF01406.19 EGG17838.1 - 5.1e-104 347.8 3.4 1.3e-103 346.5 3.4 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGG17838.1 - 3e-12 46.0 8.2 1.6e-05 23.9 0.3 3.6 4 0 0 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGG17838.1 - 0.00017 20.0 0.1 0.002 16.5 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 EGG17838.1 - 0.0016 17.4 0.1 0.051 12.5 0.0 2.7 2 0 0 2 2 2 1 tRNA synthetases class I (K) APG9 PF04109.16 EGG17838.1 - 0.038 13.0 0.1 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Autophagy protein Apg9 DALR_2 PF09190.11 EGG17838.1 - 0.04 14.4 0.1 0.24 11.9 0.0 2.4 2 1 0 2 2 2 0 DALR domain DUF1853 PF08907.11 EGG17838.1 - 0.14 11.8 2.4 0.27 10.9 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1853) Fer4 PF00037.27 EGG17839.1 - 1.5e-14 53.1 16.4 1.6e-08 34.0 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGG17839.1 - 1.4e-12 48.0 9.4 2.3e-12 47.3 9.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGG17839.1 - 2.6e-11 44.3 5.5 3.8e-05 24.5 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EGG17839.1 - 5.1e-10 39.3 3.9 0.00013 22.0 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGG17839.1 - 7.3e-09 35.9 1.1 0.00049 20.5 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGG17839.1 - 9.9e-09 35.2 9.4 1.8e-08 34.4 9.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGG17839.1 - 3.3e-08 33.5 21.0 8.8e-06 25.7 12.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EGG17839.1 - 2.6e-07 30.4 17.8 0.00036 20.5 5.4 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EGG17839.1 - 1e-06 28.5 12.5 0.0025 17.8 2.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EGG17839.1 - 7.4e-06 26.1 11.7 0.00046 20.5 2.5 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EGG17839.1 - 0.00097 19.6 12.3 0.052 14.1 12.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 EGG17839.1 - 0.013 16.0 14.7 0.65 10.6 2.7 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 EGG17839.1 - 0.033 14.4 5.6 1.1 9.6 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 EGG17839.1 - 0.051 13.8 8.8 0.76 10.0 1.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EGG17839.1 - 0.17 12.9 16.3 0.32 12.0 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 EGG17839.1 - 0.46 10.6 6.0 2.3 8.4 0.8 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 EGG17839.1 - 0.85 10.5 11.8 2.2 9.2 1.7 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain RNB PF00773.19 EGG17840.1 - 7e-39 134.1 0.2 2.7e-38 132.1 0.0 1.8 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 EGG17840.1 - 5.9e-21 74.3 0.0 1.4e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EGG17840.1 - 1.2e-14 54.7 3.7 2.5e-14 53.7 3.7 1.5 1 0 0 1 1 1 1 PIN domain Rrp44_CSD1 PF17216.3 EGG17840.1 - 8.3e-09 35.3 0.0 2.4e-08 33.9 0.0 1.8 1 1 1 2 2 2 1 Rrp44-like cold shock domain CSD2 PF17876.1 EGG17840.1 - 6.1e-08 32.7 0.1 2.7e-06 27.5 0.0 3.0 3 0 0 3 3 3 1 Cold shock domain Lambda_tail_I PF06805.12 EGG17840.1 - 0.15 12.4 0.0 4 7.9 0.0 2.8 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly protein I RNB PF00773.19 EGG17841.1 - 4.8e-16 59.0 0.9 9.3e-16 58.1 0.9 1.4 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 EGG17841.1 - 4.5e-12 45.8 0.3 1.2e-11 44.4 0.3 1.7 1 0 0 1 1 1 1 S1 domain Dis3l2_C_term PF17877.1 EGG17841.1 - 0.00046 20.5 5.4 0.0025 18.1 4.3 2.5 1 1 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CDC45 PF02724.14 EGG17841.1 - 0.0036 15.7 2.1 0.0037 15.6 2.1 1.1 1 0 0 1 1 1 1 CDC45-like protein FAD-oxidase_C PF02913.19 EGG17842.1 - 1.6e-61 208.1 0.0 2.4e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGG17842.1 - 7.8e-38 129.3 0.0 1.9e-37 128.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain ANF_receptor PF01094.28 EGG17842.1 - 0.071 12.2 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Receptor family ligand binding region Synaptobrevin PF00957.21 EGG17843.1 - 4.8e-32 109.6 2.6 6.6e-32 109.2 2.6 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGG17843.1 - 1.9e-24 85.5 0.0 3.3e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Ferlin_C PF16165.5 EGG17843.1 - 0.043 13.8 0.2 0.043 13.8 0.2 1.5 2 0 0 2 2 2 0 Ferlin C-terminus TMEM154 PF15102.6 EGG17843.1 - 0.047 13.6 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Use1 PF09753.9 EGG17843.1 - 0.14 11.8 2.0 0.22 11.2 2.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 Tachystatin_B PF11478.8 EGG17844.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B Mpv17_PMP22 PF04117.12 EGG17846.1 - 3e-12 46.6 0.1 5.7e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Pex14_N PF04695.13 EGG17847.1 - 0.0077 16.9 2.3 0.018 15.7 2.3 1.6 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region GT87 PF09594.10 EGG17847.1 - 0.013 15.2 1.2 0.022 14.5 1.2 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 87 FPN1 PF06963.12 EGG17847.1 - 0.061 11.9 0.9 0.12 10.9 0.3 1.7 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Spt20 PF12090.8 EGG17847.1 - 0.076 12.6 15.7 0.14 11.7 15.7 1.3 1 0 0 1 1 1 0 Spt20 family DUF2967 PF11179.8 EGG17847.1 - 0.19 9.8 4.1 0.25 9.4 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF4834 PF16118.5 EGG17847.1 - 0.3 12.1 7.3 4.7 8.2 5.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Zip PF02535.22 EGG17847.1 - 0.39 9.9 0.0 0.39 9.9 0.0 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter DUF533 PF04391.12 EGG17847.1 - 0.44 10.1 7.1 5.7 6.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF533) DUF3314 PF11771.8 EGG17847.1 - 1.7 8.8 5.0 2.1 8.4 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3314) DivIC PF04977.15 EGG17847.1 - 2 8.2 11.9 18 5.2 7.1 3.2 3 0 0 3 3 3 0 Septum formation initiator RICTOR_phospho PF14665.6 EGG17849.1 - 0.0074 16.6 1.8 0.06 13.7 0.1 2.8 1 1 2 3 3 3 1 Rapamycin-insensitive companion of mTOR, phosphorylation-site Macoilin PF09726.9 EGG17850.1 - 0.8 8.2 11.4 2.8 6.4 3.9 2.3 2 0 0 2 2 2 0 Macoilin family OrfB_Zn_ribbon PF07282.11 EGG17851.1 - 2.3e-10 40.2 1.2 0.016 15.1 0.0 4.7 4 0 0 4 4 4 3 Putative transposase DNA-binding domain PX PF00787.24 EGG17852.1 - 1.1e-09 38.3 0.6 1.1e-09 38.3 0.6 2.8 2 1 1 3 3 3 1 PX domain DUF1702 PF08012.11 EGG17853.1 - 0.14 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) TRAP_alpha PF03896.16 EGG17854.1 - 0.00039 19.7 0.1 0.00075 18.8 0.1 1.4 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Pup PF05639.11 EGG17854.1 - 0.12 13.3 4.2 0.11 13.5 1.2 2.4 2 0 0 2 2 2 0 Pup-like protein Beach PF02138.18 EGG17855.1 - 1.7e-122 408.1 0.3 1.7e-122 408.1 0.3 2.6 3 0 0 3 3 3 1 Beige/BEACH domain DUF4704 PF15787.5 EGG17855.1 - 2.5e-32 112.2 9.4 1.1e-31 110.2 9.4 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 EGG17855.1 - 4.1e-13 49.3 0.0 4.1e-13 49.3 0.0 4.5 5 0 0 5 5 5 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EGG17856.1 - 3.4e-08 34.0 2.4 1.4e-05 25.8 0.4 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG17856.1 - 0.017 15.4 0.1 0.07 13.4 0.1 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3430 PF11912.8 EGG17857.1 - 9.1e-21 74.9 20.2 1e-20 74.7 20.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) MFS_1 PF07690.16 EGG17858.1 - 6.4e-22 78.0 9.3 6.1e-08 32.0 0.0 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_3 PF05977.13 EGG17858.1 - 2.5e-16 59.2 8.5 1.3e-10 40.3 0.2 3.1 2 1 1 3 3 3 3 Transmembrane secretion effector DUF3169 PF11368.8 EGG17858.1 - 0.0065 16.0 0.7 0.0065 16.0 0.7 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF3169) Cwf_Cwc_15 PF04889.12 EGG17858.1 - 0.0085 15.9 0.8 0.0085 15.9 0.8 2.3 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Nipped-B_C PF12830.7 EGG17858.1 - 0.022 14.7 1.6 0.15 12.0 1.6 2.3 1 1 0 1 1 1 0 Sister chromatid cohesion C-terminus DUF4149 PF13664.6 EGG17858.1 - 0.62 10.4 8.3 2.1 8.7 3.8 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4149) CobT PF06213.12 EGG17858.1 - 1.8 7.9 20.8 0.42 10.0 5.3 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Connexin PF00029.19 EGG17858.1 - 6 6.6 7.9 9.5 5.9 2.7 2.6 2 0 0 2 2 2 0 Connexin Pex14_N PF04695.13 EGG17858.1 - 6.5 7.4 15.2 2.8 8.6 0.0 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PH_2 PF08458.10 EGG17859.1 - 0.019 15.3 5.4 0.19 12.1 0.2 2.8 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Mcp5_PH PF12814.7 EGG17859.1 - 0.058 13.5 0.3 0.24 11.5 0.3 2.1 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EGG17859.1 - 0.23 12.0 7.0 3.5 8.2 7.0 2.9 1 1 0 1 1 1 0 PH domain Zip PF02535.22 EGG17859.1 - 8.8 5.4 8.8 0.25 10.5 1.7 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter ESCRT-II PF05871.12 EGG17860.1 - 4.4e-51 172.8 4.3 5.7e-51 172.5 4.3 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit CwfJ_C_1 PF04677.15 EGG17861.1 - 5.6e-28 97.3 0.4 1.9e-27 95.6 0.1 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EGG17861.1 - 1.2e-08 35.7 1.7 1.2e-08 35.7 1.7 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CPSF73-100_C PF11718.8 EGG17861.1 - 0.04 13.5 1.9 4.8 6.7 0.2 2.4 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Androgen_recep PF02166.16 EGG17861.1 - 1.7 7.4 5.7 2.8 6.7 5.7 1.2 1 0 0 1 1 1 0 Androgen receptor Pam16 PF03656.13 EGG17862.1 - 2.8e-16 59.7 0.1 3.2e-16 59.5 0.1 1.0 1 0 0 1 1 1 1 Pam16 Usp PF00582.26 EGG17863.1 - 9.1e-27 94.3 0.0 1e-26 94.1 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Citrate_ly_lig PF08218.11 EGG17863.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Citrate lyase ligase C-terminal domain ParA PF10609.9 EGG17864.1 - 3e-99 331.4 0.6 3.8e-99 331.1 0.6 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGG17864.1 - 6.7e-12 45.6 0.0 2e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGG17864.1 - 2e-06 27.9 0.3 2e-06 27.9 0.3 2.2 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 EGG17864.1 - 8.1e-06 25.5 0.4 0.043 13.3 0.0 2.4 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 EGG17864.1 - 1.3e-05 24.7 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EGG17864.1 - 0.01 15.0 1.6 0.19 10.8 0.1 3.0 2 1 1 3 3 3 0 Anion-transporting ATPase AAA_26 PF13500.6 EGG17864.1 - 0.13 12.1 2.1 0.88 9.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain YhhN PF07947.14 EGG17865.1 - 0.0067 16.0 23.2 0.0092 15.6 4.4 3.4 4 0 0 4 4 4 2 YhhN family DUF5383 PF17355.2 EGG17865.1 - 0.068 13.5 0.3 0.068 13.5 0.3 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5383) Sulfatase_C PF14707.6 EGG17865.1 - 0.1 13.4 0.4 0.21 12.3 0.4 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Gemini_mov PF01708.16 EGG17865.1 - 0.11 12.3 0.6 6 6.7 0.0 2.8 2 0 0 2 2 2 0 Geminivirus putative movement protein BB_PF PF18063.1 EGG17866.1 - 2.5e-52 177.5 0.5 3.1e-52 177.2 0.5 1.1 1 0 0 1 1 1 1 Beta barrel Pore-forming domain BB_PF PF18063.1 EGG17867.1 - 3.1e-54 183.7 1.1 3.5e-54 183.5 1.1 1.0 1 0 0 1 1 1 1 Beta barrel Pore-forming domain TAL_FSA PF00923.19 EGG17868.1 - 2.9e-93 312.4 0.7 3.3e-93 312.2 0.7 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase AAA PF00004.29 EGG17869.1 - 4.9e-12 46.4 0.3 2.5e-11 44.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGG17869.1 - 4e-07 30.1 4.5 6.5e-05 22.9 0.0 3.4 3 0 0 3 3 3 2 Rad17 P-loop domain RNA_helicase PF00910.22 EGG17869.1 - 3.3e-06 27.5 0.1 0.00014 22.2 0.0 3.4 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 EGG17869.1 - 5.2e-05 23.5 1.3 0.012 15.9 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGG17869.1 - 0.00011 22.3 0.0 0.00011 22.3 0.0 4.0 3 1 1 4 4 4 1 AAA domain RuvB_N PF05496.12 EGG17869.1 - 0.00012 21.8 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGG17869.1 - 0.0005 20.3 0.1 0.0014 18.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG17869.1 - 0.00087 19.7 0.0 0.0023 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGG17869.1 - 0.0023 18.5 0.0 0.0023 18.5 0.0 2.8 4 0 0 4 4 1 1 AAA domain Sigma54_activ_2 PF14532.6 EGG17869.1 - 0.0052 16.9 0.1 0.024 14.8 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain TsaE PF02367.17 EGG17869.1 - 0.0074 16.3 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EGG17869.1 - 0.0076 16.6 1.4 0.063 13.6 0.1 2.7 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 EGG17869.1 - 0.0092 15.7 0.4 0.21 11.3 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 EGG17869.1 - 0.018 15.0 0.0 0.053 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EGG17869.1 - 0.019 14.9 0.5 0.083 12.8 0.2 2.3 1 1 1 2 2 2 0 NTPase AAA_33 PF13671.6 EGG17869.1 - 0.02 15.0 0.2 0.063 13.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGG17869.1 - 0.045 13.6 0.0 0.045 13.6 0.0 3.5 5 0 0 5 5 4 0 RsgA GTPase AAA_3 PF07726.11 EGG17869.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EGG17869.1 - 0.07 13.6 4.8 0.074 13.5 0.1 3.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 EGG17869.1 - 0.27 11.1 5.3 0.13 12.1 0.6 2.6 2 1 1 3 3 3 0 NACHT domain YL1 PF05764.13 EGG17869.1 - 0.74 9.9 24.2 0.97 9.5 7.9 3.2 3 0 0 3 3 3 0 YL1 nuclear protein DUF4598 PF15370.6 EGG17869.1 - 1.8 9.1 22.5 0.23 11.9 2.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4598) Pterin_bind PF00809.22 EGG17870.1 - 3.2e-72 243.1 0.0 5.2e-72 242.5 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EGG17870.1 - 1.7e-36 125.1 0.0 3.1e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 EGG17870.1 - 5.1e-25 88.2 0.1 2.9e-24 85.7 0.0 2.1 2 0 0 2 2 2 1 Dihydroneopterin aldolase SVWC PF15430.6 EGG17871.1 - 0.00011 22.4 4.8 0.0004 20.6 4.9 1.7 1 1 1 2 2 2 2 Single domain von Willebrand factor type C SVWC PF15430.6 EGG17872.1 - 0.0042 17.3 2.3 0.0042 17.3 2.3 1.8 2 0 0 2 2 2 1 Single domain von Willebrand factor type C SVWC PF15430.6 EGG17873.1 - 0.00032 20.9 4.5 0.00037 20.7 4.5 1.1 1 0 0 1 1 1 1 Single domain von Willebrand factor type C LytB_WW PF18342.1 EGG17873.1 - 0.15 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Endo-beta-N-acetylglucosaminidase LytB WW domain LMBR1 PF04791.16 EGG17875.1 - 1.2e-127 427.0 24.2 1.2e-127 427.0 24.2 1.5 2 0 0 2 2 2 1 LMBR1-like membrane protein SGTA_dimer PF16546.5 EGG17877.1 - 0.048 13.4 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 Homodimerisation domain of SGTA TFIIA PF03153.13 EGG17877.1 - 0.13 12.3 16.1 0.15 12.0 16.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 EGG17877.1 - 1.3 8.0 26.4 2.2 7.2 26.4 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HTH_55 PF18622.1 EGG17878.1 - 3.7 7.9 11.6 1.1e+02 3.2 11.5 2.5 1 1 0 1 1 1 0 RctB helix turn helix domain LRR_4 PF12799.7 EGG17880.1 - 8.4e-30 102.3 39.1 1e-06 28.9 1.7 7.4 2 1 9 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG17880.1 - 1.7e-27 95.0 29.0 4.1e-07 29.7 2.4 5.8 2 1 5 7 7 7 7 Leucine rich repeat LRR_1 PF00560.33 EGG17880.1 - 3.7e-11 42.0 24.1 4.6 8.2 0.7 10.8 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.6 EGG17880.1 - 0.072 13.2 36.9 18 5.7 0.0 10.4 11 0 0 11 11 11 0 Leucine Rich repeat LRR_9 PF14580.6 EGG17880.1 - 0.089 12.3 17.2 0.76 9.3 4.3 3.1 1 1 3 4 4 4 0 Leucine-rich repeat Tropomyosin PF00261.20 EGG17881.1 - 0.021 14.2 32.9 0.048 13.0 32.9 1.5 1 0 0 1 1 1 0 Tropomyosin ERM PF00769.19 EGG17881.1 - 0.25 11.1 43.2 0.037 13.8 38.8 1.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family PreAtp-grasp PF18604.1 EGG17881.1 - 0.26 10.9 3.1 0.39 10.4 0.3 2.4 2 1 1 3 3 3 0 Pre ATP-grasp domain CENP-F_leu_zip PF10473.9 EGG17881.1 - 0.28 11.2 43.6 2.4 8.2 1.0 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EGG17881.1 - 0.8 8.5 43.9 0.067 12.1 15.9 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein CorA PF01544.18 EGG17881.1 - 1.1 8.5 21.8 0.044 13.1 9.4 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein GAS PF13851.6 EGG17881.1 - 1.3 8.3 40.9 0.91 8.8 15.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PhoU PF01895.19 EGG17881.1 - 5.1 7.6 13.0 4.1 7.9 0.7 3.4 2 1 1 3 3 3 0 PhoU domain ApoO PF09769.9 EGG17881.1 - 6 6.8 12.2 2.6 8.0 3.7 2.8 1 1 1 2 2 2 0 Apolipoprotein O ADIP PF11559.8 EGG17881.1 - 6.1 6.9 36.7 0.65 10.1 14.1 2.7 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 EGG17881.1 - 8.6 6.5 44.2 0.29 11.3 15.1 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) tRNA-synt_1g PF09334.11 EGG17882.1 - 6.2e-102 341.3 1.0 3.4e-101 338.8 1.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGG17882.1 - 1.9e-21 76.0 3.9 4.1e-09 35.3 1.2 4.1 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EGG17882.1 - 1.1e-09 38.0 0.1 0.0003 20.3 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EGG17882.1 - 0.0034 17.4 0.1 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA Mucin PF01456.17 EGG17882.1 - 2.7 8.0 19.0 5 7.1 19.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 EGG17882.1 - 5.5 5.1 20.4 9.9 4.2 20.4 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FSA_C PF10479.9 EGG17882.1 - 7.1 4.6 11.3 9.9 4.1 11.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Tetraspanin PF00335.20 EGG17883.1 - 1.2e-05 25.1 14.3 1.2e-05 25.1 14.3 1.9 1 1 1 2 2 2 1 Tetraspanin family Tweety PF04906.13 EGG17883.1 - 0.061 12.0 1.0 0.093 11.4 1.0 1.3 1 0 0 1 1 1 0 Tweety CD20 PF04103.15 EGG17883.1 - 0.55 10.3 11.2 0.84 9.7 11.2 1.4 1 1 0 1 1 1 0 CD20-like family DUF4728 PF15860.5 EGG17883.1 - 0.71 10.6 13.6 0.044 14.5 7.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) TssN PF17555.2 EGG17883.1 - 1.7 8.0 13.2 3.1 7.1 13.2 1.4 1 1 0 1 1 1 0 Type VI secretion system, TssN VPDSG-CTERM PF18205.1 EGG17883.1 - 2.9 7.8 7.7 0.28 11.0 2.0 2.3 2 0 0 2 2 2 0 VPDSG-CTERM motif MARVEL PF01284.23 EGG17883.1 - 4.5 7.3 15.2 6.3 6.8 15.2 1.2 1 0 0 1 1 1 0 Membrane-associating domain PalH PF08733.10 EGG17883.1 - 4.8 6.1 10.6 5.5 5.9 10.6 1.2 1 0 0 1 1 1 0 PalH/RIM21 Ank_4 PF13637.6 EGG17884.1 - 8.8e-09 35.7 4.3 1.2 9.8 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG17884.1 - 5.3e-07 30.1 2.8 0.17 12.5 0.8 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG17884.1 - 9e-05 22.6 0.9 15 6.6 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EGG17884.1 - 0.002 18.4 6.6 20 5.7 0.1 5.5 2 2 4 6 6 6 2 Ankyrin repeats (many copies) EF-hand_4 PF12763.7 EGG17885.1 - 2.4e-37 127.0 11.0 8.9e-14 51.3 0.0 5.2 3 1 2 5 5 5 3 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.6 EGG17885.1 - 3.1e-05 23.5 2.5 1.3 9.2 0.1 4.7 4 0 0 4 4 4 2 EF-hand domain HAP1_N PF04849.13 EGG17885.1 - 5.2e-05 22.6 16.6 5.2e-05 22.6 16.6 3.1 1 1 2 3 3 3 1 HAP1 N-terminal conserved region EF-hand_7 PF13499.6 EGG17885.1 - 0.00027 21.3 4.0 0.41 11.1 0.6 4.2 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 EGG17885.1 - 0.00054 19.3 11.5 0.28 10.8 0.0 5.0 5 0 0 5 5 5 3 EF hand Spc7 PF08317.11 EGG17885.1 - 0.021 13.7 43.9 0.046 12.6 24.0 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein EF-hand_8 PF13833.6 EGG17885.1 - 0.36 10.7 4.0 4.4 7.2 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain pair DUF1108 PF06531.11 EGG17888.1 - 0.18 12.1 3.1 5.8 7.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1108) SSP160 PF06933.11 EGG17888.1 - 1.7 6.8 12.4 2.5 6.2 12.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DivIC PF04977.15 EGG17888.1 - 7.2 6.5 8.2 8.7 6.2 0.1 2.9 2 0 0 2 2 2 0 Septum formation initiator F-box-like PF12937.7 EGG17890.1 - 0.0046 16.8 2.5 0.32 10.9 0.2 3.3 2 2 0 2 2 2 2 F-box-like V-ATPase_H_C PF11698.8 EGG17890.1 - 0.0079 16.3 7.4 0.096 12.8 4.0 2.9 2 1 0 2 2 2 2 V-ATPase subunit H ILEI PF15711.5 EGG17891.1 - 1.4e-66 220.9 15.0 8.2e-13 48.7 0.3 5.8 5 0 0 5 5 5 5 Interleukin-like EMT inducer Laminin_G_3 PF13385.6 EGG17891.1 - 8.7e-23 81.2 9.5 2.5e-13 50.5 0.7 3.9 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 EGG17891.1 - 5.5e-08 33.4 0.1 0.00012 22.6 0.1 3.2 3 0 0 3 3 3 2 Laminin G domain Laminin_G_1 PF00054.23 EGG17891.1 - 0.00014 22.1 0.0 0.036 14.3 0.0 2.5 2 0 0 2 2 2 2 Laminin G domain EGF_2 PF07974.13 EGG17893.1 - 0.0013 19.0 9.1 0.0031 17.8 9.1 1.6 1 0 0 1 1 1 1 EGF-like domain fn3 PF00041.21 EGG17893.1 - 0.048 14.0 2.9 6 7.3 0.0 4.4 4 0 0 4 4 4 0 Fibronectin type III domain Apo-VLDL-II PF05418.11 EGG17894.1 - 0.029 14.9 0.0 0.07 13.7 0.0 1.7 1 0 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) F-box-like PF12937.7 EGG17895.1 - 0.0024 17.8 3.0 0.82 9.6 0.1 4.7 3 2 0 3 3 3 2 F-box-like F-box PF00646.33 EGG17895.1 - 1.5 8.8 7.2 15 5.6 0.2 4.4 4 0 0 4 4 4 0 F-box domain DUF2149 PF09919.9 EGG17896.1 - 0.054 13.8 0.1 0.067 13.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) LMF1 PF06762.14 EGG17899.1 - 3.2e-117 392.4 22.2 1.3e-115 387.0 22.2 2.3 1 1 0 1 1 1 1 Lipase maturation factor PS_Dcarbxylase PF02666.15 EGG17901.1 - 6.6e-61 205.3 0.0 8e-61 205.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Melibiase_2 PF16499.5 EGG17902.1 - 1.7e-76 257.2 4.4 2.4e-76 256.6 4.4 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EGG17902.1 - 1.3e-20 73.2 0.1 1.3e-20 73.2 0.1 2.1 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EGG17902.1 - 0.00016 20.7 0.0 0.00033 19.7 0.0 1.4 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 EGG17902.1 - 0.00021 21.4 0.0 0.00041 20.5 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Glyco_hydro_30C PF17189.4 EGG17902.1 - 0.0091 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain YceG PF02618.16 EGG17903.1 - 0.00087 18.9 0.1 0.00087 18.9 0.1 2.2 2 1 0 2 2 2 1 YceG-like family RRM_1 PF00076.22 EGG17903.1 - 0.0029 17.4 0.0 0.007 16.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 EGG17903.1 - 0.081 11.2 11.6 0.083 11.2 11.6 1.2 1 0 0 1 1 1 0 CDC45-like protein PG_binding_3 PF09374.10 EGG17903.1 - 0.091 13.0 0.2 0.66 10.3 0.0 2.1 2 0 0 2 2 2 0 Predicted Peptidoglycan domain RRN3 PF05327.11 EGG17903.1 - 0.77 8.2 13.8 1.1 7.8 13.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.14 EGG17903.1 - 2.5 7.8 21.0 0.21 11.3 16.0 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF4637 PF15470.6 EGG17903.1 - 3.7 7.3 13.0 7.8 6.2 13.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2457 PF10446.9 EGG17903.1 - 4.8 6.2 25.2 7.6 5.6 25.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TatD_DNase PF01026.21 EGG17904.1 - 1.7e-60 204.6 0.0 2.1e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase CABIT PF12736.7 EGG17904.1 - 0.003 16.9 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Cell-cycle sustaining, positive selection, Beta_protein PF14350.6 EGG17904.1 - 0.054 12.9 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Beta protein PHA_gran_rgn PF09650.10 EGG17904.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) BK_channel_a PF03493.18 EGG17906.1 - 1.8e-21 76.1 0.0 6.3e-21 74.4 0.0 2.0 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 EGG17906.1 - 3.5e-17 62.5 18.9 6e-17 61.7 18.9 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGG17906.1 - 3.3e-11 43.0 4.3 9.4e-11 41.5 4.3 1.8 1 0 0 1 1 1 1 Ion channel DUF5605 PF18310.1 EGG17908.1 - 0.045 13.7 1.0 0.09 12.7 1.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5605) FNIP PF05725.12 EGG17909.1 - 9.5e-45 150.5 26.3 2.5e-09 37.1 0.4 9.5 5 3 5 10 10 10 10 FNIP Repeat Peptidase_C1 PF00112.23 EGG17910.1 - 1.3e-48 165.9 4.5 1.9e-48 165.4 4.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.26 EGG17910.1 - 2.6e-05 25.1 0.9 6.1e-05 23.9 0.9 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_C1_2 PF03051.15 EGG17910.1 - 0.008 15.0 0.9 1.1 8.0 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 EGG17911.1 - 2.4e-49 168.4 3.2 3.7e-49 167.8 3.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.26 EGG17911.1 - 4.4e-07 30.8 2.0 4.4e-07 30.8 2.0 2.2 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Peptidase_C1_2 PF03051.15 EGG17911.1 - 0.0011 17.8 0.6 0.046 12.5 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C39_2 PF13529.6 EGG17911.1 - 0.015 15.9 0.1 0.062 13.8 0.0 2.0 2 0 0 2 2 2 0 Peptidase_C39 like family Trypan_PARP PF05887.11 EGG17911.1 - 0.4 10.7 13.4 0.7 9.9 13.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mucin PF01456.17 EGG17911.1 - 1.4 8.9 28.1 6.3 6.8 26.7 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Inhibitor_I29 PF08246.12 EGG17912.1 - 1.4e-11 44.6 10.3 7.2e-11 42.4 10.3 2.0 1 1 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Methyltr_RsmB-F PF01189.17 EGG17913.1 - 1.3e-34 119.6 0.0 2.1e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EGG17913.1 - 2e-05 24.8 0.0 4.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PUA PF01472.20 EGG17913.1 - 2.3e-05 24.3 0.2 5e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 PUA domain Methyltransf_15 PF09445.10 EGG17913.1 - 3.9e-05 23.3 0.0 0.0032 17.1 0.0 2.4 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.6 EGG17913.1 - 0.00054 20.9 0.0 0.0074 17.3 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Macoilin PF09726.9 EGG17914.1 - 0.16 10.5 1.6 0.16 10.5 1.6 1.1 1 0 0 1 1 1 0 Macoilin family SSP160 PF06933.11 EGG17914.1 - 1.6 6.9 10.2 2 6.5 10.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SR-25 PF10500.9 EGG17914.1 - 1.7 8.2 13.3 2.4 7.7 13.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dcc1 PF09724.9 EGG17915.1 - 1.3e-75 254.8 3.2 1.5e-75 254.6 3.2 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 MeaB PF03308.16 EGG17916.1 - 3.8e-90 301.5 0.1 5.5e-90 301.0 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 EGG17916.1 - 5.4e-08 32.6 0.1 3.2e-07 30.1 0.1 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 EGG17916.1 - 0.00016 21.5 0.4 0.0068 16.2 0.0 2.5 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EGG17916.1 - 0.00075 19.3 0.0 0.0024 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG17916.1 - 0.0067 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EGG17916.1 - 0.0095 16.5 2.5 0.033 14.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGG17916.1 - 0.015 15.0 0.0 0.044 13.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGG17916.1 - 0.021 15.2 0.3 0.13 12.6 0.0 2.5 3 0 0 3 3 3 0 RNA helicase MMR_HSR1 PF01926.23 EGG17916.1 - 0.024 14.7 0.7 0.14 12.2 0.1 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase KAP_NTPase PF07693.14 EGG17916.1 - 0.028 13.7 0.0 0.055 12.7 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.27 EGG17916.1 - 0.034 14.6 0.3 0.11 13.0 0.1 1.9 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 EGG17916.1 - 0.053 14.1 1.1 0.16 12.5 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGG17916.1 - 0.061 13.7 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 EGG17916.1 - 0.067 13.1 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 EGG17916.1 - 0.068 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGG17916.1 - 0.094 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 EGG17916.1 - 0.096 12.7 0.2 6.8 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EGG17916.1 - 0.11 13.0 0.0 0.36 11.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGG17916.1 - 0.11 12.6 0.0 0.63 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EGG17917.1 - 8.6e-16 58.2 0.4 5.6e-15 55.6 0.0 2.6 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG17917.1 - 2.6e-08 33.6 0.1 5.8e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Ras family LRR_8 PF13855.6 EGG17917.1 - 5.2e-08 32.5 0.4 3.2e-07 30.0 0.5 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGG17917.1 - 1.4e-07 31.7 5.5 9.2e-07 29.1 3.0 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGG17917.1 - 0.00054 20.2 2.1 5.5 7.9 0.7 4.1 3 0 0 3 3 3 1 Leucine Rich Repeat Arf PF00025.21 EGG17917.1 - 0.00097 18.6 0.0 0.0023 17.4 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG17917.1 - 0.0028 17.0 0.0 0.0096 15.3 0.0 2.0 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Phi-29_GP4 PF05464.11 EGG17917.1 - 0.074 13.3 0.1 10 6.4 0.0 2.5 2 0 0 2 2 2 0 Phi-29-like late genes activator (early protein GP4) DUF4472 PF14739.6 EGG17917.1 - 0.12 13.1 0.1 0.32 11.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) AAA_23 PF13476.6 EGG17917.1 - 1.8 9.0 7.6 0.38 11.2 2.2 2.5 1 1 1 2 2 2 0 AAA domain CH PF00307.31 EGG17918.1 - 1e-21 77.1 0.0 1e-21 77.1 0.0 4.5 6 1 1 7 7 7 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGG17918.1 - 1.1e-05 25.2 0.0 3.3e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 CAMSAP CH domain Ras PF00071.22 EGG17920.1 - 0.0092 15.6 0.1 0.02 14.5 0.1 1.5 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 EGG17920.1 - 0.022 15.4 0.0 0.096 13.3 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) SMN PF06003.12 EGG17920.1 - 0.63 9.2 3.1 1.1 8.4 3.1 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Secretin_N_2 PF07655.13 EGG17920.1 - 1.3 9.6 17.7 1.3 9.6 9.4 2.8 2 0 0 2 2 2 0 Secretin N-terminal domain FYVE PF01363.21 EGG17921.1 - 1.3e-18 66.9 9.8 2.7e-18 65.9 9.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger Arrestin_N PF00339.29 EGG17921.1 - 3.9e-08 33.5 0.4 7.3e-06 26.1 0.4 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGG17921.1 - 0.0063 17.0 13.0 0.039 14.4 3.1 4.8 3 2 1 4 4 4 1 Arrestin (or S-antigen), C-terminal domain FYVE_2 PF02318.16 EGG17921.1 - 0.34 11.1 10.8 0.089 13.0 6.6 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_4 PF14570.6 EGG17921.1 - 2.7 7.9 7.1 6.9 6.6 0.0 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EGG17921.1 - 8.6 6.4 12.3 24 5.0 12.4 1.7 1 1 0 1 1 1 0 zinc-RING finger domain PRA1 PF03208.19 EGG17922.1 - 2.7e-27 95.2 3.5 3e-27 95.0 3.5 1.0 1 0 0 1 1 1 1 PRA1 family protein TMEM89 PF15098.6 EGG17922.1 - 0.11 12.7 2.5 0.93 9.7 0.2 2.4 2 1 1 3 3 3 0 TMEM89 protein family zf-UBR PF02207.20 EGG17925.1 - 1.4e-18 66.8 6.7 1.4e-18 66.8 6.7 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) GAGA_bind PF06217.12 EGG17925.1 - 9.3 6.4 11.2 2.9 8.1 0.5 2.7 2 0 0 2 2 2 0 GAGA binding protein-like family UbiA PF01040.18 EGG17926.1 - 7.7e-15 54.9 9.3 9.1e-15 54.6 9.3 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family UbiA PF01040.18 EGG17927.1 - 7e-24 84.5 7.5 1e-23 84.0 7.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3050 PF11251.8 EGG17927.1 - 0.11 12.1 0.2 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) Trehalase PF01204.18 EGG17928.1 - 1.9e-143 479.0 0.2 2.2e-143 478.8 0.2 1.0 1 0 0 1 1 1 1 Trehalase Pkinase_Tyr PF07714.17 EGG17929.1 - 8.3e-56 189.1 0.0 1.7e-55 188.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGG17929.1 - 2.6e-53 181.1 0.0 5e-53 180.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 EGG17929.1 - 0.0023 16.9 0.1 0.0023 16.9 0.1 2.2 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGG17929.1 - 0.0069 16.3 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG17929.1 - 0.052 12.9 0.0 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 Kinase-like PRMT5 PF05185.16 EGG17930.1 - 2.1e-69 232.8 0.0 3.4e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 EGG17930.1 - 7.1e-69 231.9 6.0 1e-68 231.4 6.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 EGG17930.1 - 1.2e-49 168.5 6.6 2.6e-49 167.5 6.6 1.6 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 EGG17930.1 - 0.00017 21.4 0.1 0.00052 19.8 0.1 1.7 1 1 0 1 1 1 1 Met-10+ like-protein DUF3439 PF11921.8 EGG17930.1 - 7.9 6.5 17.9 5 7.1 15.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HMGL-like PF00682.19 EGG17932.1 - 3.8e-60 203.7 0.0 5.8e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 HMGL-like Terminase_2 PF03592.16 EGG17932.1 - 0.12 12.9 0.3 0.26 11.8 0.3 1.5 1 0 0 1 1 1 0 Terminase small subunit SfsA PF03749.13 EGG17932.1 - 0.15 12.0 0.1 0.7 9.8 0.0 2.0 2 0 0 2 2 2 0 Sugar fermentation stimulation protein RE domain AAA PF00004.29 EGG17933.1 - 8.4e-43 146.0 0.0 1.5e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG17933.1 - 4.5e-10 39.2 0.9 9.6e-10 38.1 0.9 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGG17933.1 - 1.1e-07 32.4 0.0 0.00013 22.4 0.0 2.8 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 EGG17933.1 - 2.4e-07 30.9 0.1 3.5e-06 27.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGG17933.1 - 3.4e-06 26.9 0.0 8.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGG17933.1 - 5.1e-05 23.4 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 EGG17933.1 - 0.00013 21.9 0.0 0.00031 20.6 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EGG17933.1 - 0.00019 21.7 0.1 0.022 15.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGG17933.1 - 0.00096 19.5 0.0 0.0026 18.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 EGG17933.1 - 0.0014 19.2 0.1 0.0091 16.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 EGG17933.1 - 0.0021 17.2 0.0 0.0036 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EGG17933.1 - 0.0024 17.6 0.0 0.0061 16.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EGG17933.1 - 0.0026 17.0 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 EGG17933.1 - 0.003 17.1 0.0 0.007 15.9 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGG17933.1 - 0.005 16.2 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGG17933.1 - 0.0056 16.4 0.0 0.022 14.5 0.0 1.9 1 1 1 2 2 2 1 Sigma-54 interaction domain TsaE PF02367.17 EGG17933.1 - 0.0057 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EGG17933.1 - 0.0098 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 EGG17933.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 EGG17933.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGG17933.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGG17933.1 - 0.028 14.4 0.0 0.069 13.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 EGG17933.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGG17933.1 - 0.035 14.3 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGG17933.1 - 0.046 14.0 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGG17933.1 - 0.049 13.0 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 EGG17933.1 - 0.075 12.9 0.1 0.24 11.3 0.0 1.9 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 EGG17933.1 - 0.077 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 EGG17933.1 - 0.086 13.4 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 EGG17933.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGG17933.1 - 0.12 12.1 0.6 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 EGG17933.1 - 0.13 11.4 0.1 0.47 9.6 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase AAA_19 PF13245.6 EGG17933.1 - 0.16 12.3 0.0 0.37 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF1043 PF06295.12 EGG17933.1 - 0.22 11.5 3.0 0.41 10.7 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DCP1 PF06058.13 EGG17934.1 - 1.9e-10 40.7 0.8 1.2e-08 34.8 0.1 3.2 3 1 1 4 4 4 2 Dcp1-like decapping family DUF4407 PF14362.6 EGG17934.1 - 0.015 14.6 15.6 0.028 13.8 15.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Hamartin PF04388.12 EGG17934.1 - 0.39 9.3 31.0 0.49 9.0 31.0 1.1 1 0 0 1 1 1 0 Hamartin protein PIG-S PF10510.9 EGG17938.1 - 3.9e-103 346.0 17.1 1.7e-97 327.4 9.0 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein DNA_repr_REX1B PF14966.6 EGG17939.1 - 3.1e-27 95.1 3.3 3.8e-26 91.6 0.3 2.2 2 0 0 2 2 2 1 DNA repair REX1-B Ntox28 PF15605.6 EGG17939.1 - 0.00089 19.5 0.7 0.0017 18.5 0.7 1.5 1 0 0 1 1 1 1 Bacterial toxin 28 DHC_N2 PF08393.13 EGG17939.1 - 0.0035 16.5 3.7 0.035 13.2 0.5 2.2 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 2 Hit1_C PF18268.1 EGG17939.1 - 0.017 15.3 0.1 0.058 13.5 0.1 1.9 1 0 0 1 1 1 0 Hit1 C-terminal NPV_P10 PF05531.12 EGG17939.1 - 0.071 13.6 0.5 0.071 13.6 0.5 2.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ALS_ss_C PF10369.9 EGG17939.1 - 0.077 13.2 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Small subunit of acetolactate synthase MobC PF05713.11 EGG17939.1 - 0.46 11.0 2.9 1.7 9.1 0.1 3.0 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) FapA PF03961.13 EGG17939.1 - 0.58 8.7 7.7 0.31 9.6 3.5 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A PTPS PF01242.19 EGG17940.1 - 3.1e-28 98.2 0.2 3.7e-28 98.0 0.2 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Glyco_hydro_38N PF01074.22 EGG17941.1 - 1.7e-65 221.3 6.0 2.1e-65 221.0 5.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Kelch_5 PF13854.6 EGG17941.1 - 1.8e-26 91.7 9.7 1.4e-07 31.4 0.3 6.1 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 EGG17941.1 - 1.6e-25 88.4 3.9 2.5e-06 27.5 0.2 5.9 3 2 2 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EGG17941.1 - 7.7e-24 83.0 2.0 1.6e-07 30.7 0.7 5.3 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 EGG17941.1 - 7.7e-24 84.1 2.3 1.4e-21 76.8 0.0 4.0 3 1 1 4 4 4 1 BTB/POZ domain Kelch_3 PF13415.6 EGG17941.1 - 5.3e-23 80.8 11.3 4.2e-08 33.3 0.3 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EGG17941.1 - 2.3e-22 78.7 10.6 1.6e-07 31.2 0.9 6.2 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EGG17941.1 - 1.3e-16 59.9 2.6 7e-07 29.0 0.0 5.7 5 0 0 5 5 5 3 Kelch motif Alpha-mann_mid PF09261.11 EGG17941.1 - 1.4e-11 44.3 0.0 3.4e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 EGG17941.1 - 0.0019 18.3 0.3 0.0053 16.9 0.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro38C2 PF17677.1 EGG17941.1 - 0.0064 16.6 0.0 0.029 14.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain NES_C_h PF18208.1 EGG17941.1 - 0.044 14.0 0.5 0.74 10.1 0.1 2.7 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain tRNA-synt_1 PF00133.22 EGG17942.1 - 1.5e-216 720.3 0.1 2e-216 720.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGG17942.1 - 1.2e-23 83.8 0.0 2.9e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGG17942.1 - 3.4e-15 55.7 1.5 0.00035 19.4 0.1 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGG17942.1 - 0.00064 19.2 0.0 0.0016 17.8 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DNA_pol3_finger PF17657.1 EGG17943.1 - 0.00066 19.1 0.1 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 Bacterial DNA polymerase III alpha subunit finger domain Chal_sti_synt_C PF02797.15 EGG17943.1 - 0.0076 16.2 0.7 0.023 14.7 0.2 1.8 1 1 1 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain CC2-LZ PF16516.5 EGG17943.1 - 0.04 14.3 12.4 0.033 14.5 4.8 2.4 1 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1129 PF06570.11 EGG17943.1 - 0.55 9.7 3.8 17 4.8 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF3847 PF12958.7 EGG17943.1 - 2.5 8.3 8.6 1.9 8.7 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Goodbye PF17109.5 EGG17943.1 - 8.7 6.8 7.9 1 9.8 0.4 2.6 2 1 0 2 2 2 0 fungal STAND N-terminal Goodbye domain G8 PF10162.9 EGG17944.1 - 1.9e-23 82.8 0.8 9.2e-23 80.6 0.2 2.6 2 0 0 2 2 2 1 G8 domain TPR_2 PF07719.17 EGG17945.1 - 0.024 14.7 0.6 0.12 12.6 0.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGG17945.1 - 0.062 13.1 0.4 0.16 11.9 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG17946.1 - 0.075 13.2 0.9 0.17 12.1 0.9 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ATP13 PF12921.7 EGG17946.1 - 0.23 11.3 5.1 0.077 12.8 0.3 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase expression Peptidase_C34 PF05413.11 EGG17947.1 - 0.062 13.6 0.2 0.067 13.5 0.2 1.1 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase DEAD PF00270.29 EGG17948.1 - 4.3e-40 137.3 0.0 2e-39 135.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG17948.1 - 4.5e-33 113.9 0.0 1.7e-32 112.0 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG17948.1 - 6.1e-05 23.1 1.1 0.0037 17.3 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGG17948.1 - 0.073 12.3 0.1 0.073 12.3 0.1 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Pox_Ag35 PF03286.14 EGG17950.1 - 0.0061 16.4 1.8 0.01 15.6 1.8 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein HCO3_cotransp PF00955.21 EGG17950.1 - 0.068 12.0 9.2 0.11 11.3 9.2 1.2 1 0 0 1 1 1 0 HCO3- transporter family DUF4834 PF16118.5 EGG17950.1 - 0.085 13.8 3.0 0.22 12.5 3.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PRC2_HTH_1 PF18118.1 EGG17950.1 - 0.3 11.9 4.7 0.33 11.8 2.8 1.9 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Folate_carrier PF01770.18 EGG17950.1 - 0.6 8.8 3.6 0.84 8.3 3.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier Ashwin PF15323.6 EGG17950.1 - 4 7.4 10.1 15 5.5 8.4 2.2 2 0 0 2 2 2 0 Developmental protein SAM_2 PF07647.17 EGG17951.1 - 9.6e-06 25.6 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FlbT PF07378.11 EGG17951.1 - 0.0017 18.4 0.2 0.0031 17.6 0.2 1.5 1 0 0 1 1 1 1 Flagellar protein FlbT SAM_1 PF00536.30 EGG17951.1 - 0.0098 16.3 0.1 0.036 14.5 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 EGG17951.1 - 0.057 13.7 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PHD PF00628.29 EGG17952.1 - 1.9e-16 59.7 13.9 7.8e-09 35.3 4.2 2.6 1 1 1 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 EGG17952.1 - 0.0011 19.2 9.6 0.34 11.2 4.1 2.8 1 1 1 2 2 2 2 PHD-like zinc-binding domain C1_1 PF00130.22 EGG17952.1 - 0.0032 17.3 2.7 0.0032 17.3 2.7 2.1 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 EGG17952.1 - 0.091 12.9 9.4 0.19 11.9 3.6 2.6 1 1 1 2 2 2 0 PHD-zinc-finger like domain C1_2 PF03107.16 EGG17952.1 - 2.7 8.4 17.2 0.19 12.1 7.6 2.8 2 1 0 2 2 2 0 C1 domain DUF608 PF04685.13 EGG17953.1 - 4e-145 483.5 5.2 7.8e-145 482.6 5.2 1.5 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 EGG17953.1 - 7.9e-102 340.9 5.2 7.9e-102 340.9 5.2 2.7 3 0 0 3 3 3 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF3439 PF11921.8 EGG17953.1 - 1.7 8.7 9.1 5 7.1 9.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF885 PF05960.11 EGG17954.1 - 2e-69 235.6 0.0 7.2e-60 204.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF885) Oxidored_molyb PF00174.19 EGG17954.1 - 1.3e-57 194.2 0.0 2e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGG17954.1 - 8.2e-28 97.1 0.0 1.8e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain SPX PF03105.19 EGG17954.1 - 0.0011 18.9 2.9 0.0016 18.5 2.9 1.2 1 0 0 1 1 1 1 SPX domain Menin PF05053.13 EGG17954.1 - 0.0045 15.4 1.4 0.0067 14.8 1.4 1.1 1 0 0 1 1 1 1 Menin Macoilin PF09726.9 EGG17954.1 - 0.042 12.4 8.3 0.06 11.9 8.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF4050 PF13259.6 EGG17954.1 - 0.07 13.4 5.0 0.13 12.6 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Pacs-1 PF10254.9 EGG17954.1 - 0.14 11.1 2.5 0.23 10.4 2.5 1.3 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Cwf_Cwc_15 PF04889.12 EGG17954.1 - 0.19 11.4 5.3 0.29 10.8 5.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Apt1 PF10351.9 EGG17954.1 - 0.24 10.2 10.0 0.34 9.7 10.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.9 EGG17954.1 - 0.3 8.8 9.8 0.43 8.3 9.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3246 PF11596.8 EGG17954.1 - 0.76 9.2 14.0 1.2 8.5 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) RAP1 PF07218.11 EGG17954.1 - 1.2 7.3 11.8 2.3 6.4 11.8 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Miga PF10265.9 EGG17954.1 - 3.1 6.7 9.9 4.6 6.1 9.9 1.1 1 0 0 1 1 1 0 Mitoguardin SSP160 PF06933.11 EGG17954.1 - 4.4 5.4 16.9 6.5 4.8 16.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CLU PF13236.6 EGG17955.1 - 6.5e-53 179.8 0.0 1.9e-52 178.3 0.0 1.8 1 0 0 1 1 1 1 Clustered mitochondria SH2 PF00017.24 EGG17955.1 - 7.3e-11 42.0 0.2 4.2e-10 39.6 0.1 2.5 1 1 1 2 2 2 1 SH2 domain eIF3_p135 PF12807.7 EGG17955.1 - 2.1e-08 34.4 0.3 2.1e-08 34.4 0.3 4.4 5 0 0 5 5 5 1 Translation initiation factor eIF3 subunit 135 TPR_11 PF13414.6 EGG17955.1 - 0.00072 19.2 0.1 1.9 8.3 0.0 2.6 2 0 0 2 2 2 2 TPR repeat MIT PF04212.18 EGG17955.1 - 0.29 11.2 2.6 10 6.3 1.0 3.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.12 EGG17955.1 - 0.5 10.1 6.1 2 8.1 0.1 4.0 4 1 1 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 RGS PF00615.19 EGG17956.1 - 7e-24 84.4 1.1 3.8e-12 46.5 0.3 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain FAM199X PF15814.5 EGG17956.1 - 0.03 13.4 2.7 0.038 13.0 2.7 1.1 1 0 0 1 1 1 0 Protein family FAM199X Ashwin PF15323.6 EGG17956.1 - 0.1 12.6 8.4 0.15 12.0 8.4 1.2 1 0 0 1 1 1 0 Developmental protein CCDC106 PF15794.5 EGG17956.1 - 0.68 9.6 5.5 1 9.0 5.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Presenilin PF01080.17 EGG17956.1 - 1.7 7.3 3.2 1.9 7.2 3.2 1.1 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 EGG17956.1 - 2.8 6.2 7.1 3.5 5.9 7.1 1.1 1 0 0 1 1 1 0 Menin dNK PF01712.19 EGG17957.1 - 1.8e-40 139.0 0.4 1.8e-38 132.5 0.4 2.3 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_28 PF13521.6 EGG17957.1 - 0.00017 21.8 0.0 0.017 15.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGG17957.1 - 0.00032 20.4 0.0 0.0048 16.6 0.0 2.3 2 1 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.6 EGG17957.1 - 0.00035 21.1 1.9 0.0031 18.1 1.7 2.3 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EGG17957.1 - 0.0021 18.0 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGG17957.1 - 0.0051 17.0 0.0 0.0092 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGG17957.1 - 0.14 12.5 0.0 2.6 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 EGG17957.1 - 0.68 9.0 3.2 0.94 8.5 3.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein UCH PF00443.29 EGG17958.1 - 1.2e-18 67.6 18.2 1.2e-18 67.6 18.2 2.0 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGG17958.1 - 2.8e-13 50.0 3.7 2.2e-12 47.1 5.2 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein IMUP PF15761.5 EGG17958.1 - 0.0082 16.8 2.3 0.0082 16.8 2.3 2.5 2 0 0 2 2 2 1 Immortalisation up-regulated protein DUF3446 PF11928.8 EGG17958.1 - 0.013 15.8 11.9 0.053 13.8 6.3 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain PyrI PF01948.18 EGG17958.1 - 0.029 14.6 0.3 0.12 12.6 0.3 2.1 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain SR-25 PF10500.9 EGG17958.1 - 0.12 12.0 19.0 0.021 14.4 8.9 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-UBP_var PF17807.1 EGG17958.1 - 0.47 10.2 3.3 1.2 9.0 3.3 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger His_Phos_1 PF00300.22 EGG17959.1 - 1.4e-28 100.0 0.3 2.4e-28 99.2 0.3 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Shisa PF13908.6 EGG17960.1 - 1.3 9.2 5.7 3 8.1 5.7 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator GBP PF02263.19 EGG17961.1 - 2.7e-40 138.3 0.2 2.7e-40 138.3 0.2 2.4 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain PARP PF00644.20 EGG17961.1 - 1.7e-12 47.4 1.4 3e-11 43.3 0.0 2.9 2 1 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain BRCT PF00533.26 EGG17961.1 - 2e-12 47.3 0.1 9.4e-12 45.2 0.1 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WWE PF02825.20 EGG17961.1 - 4.3e-11 43.2 16.8 1.2e-07 32.2 0.2 4.5 4 0 0 4 4 4 3 WWE domain zf-CCHH PF10283.9 EGG17961.1 - 9.2e-10 38.3 5.4 1.9e-09 37.3 5.4 1.6 1 0 0 1 1 1 1 PBZ domain BRCT_2 PF16589.5 EGG17961.1 - 6.1e-06 26.6 1.7 3e-05 24.3 0.2 2.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGG17961.1 - 1.4e-05 24.9 1.1 3.6e-05 23.6 1.1 1.8 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 EGG17961.1 - 0.0043 17.3 0.1 0.012 15.8 0.1 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EGG17961.1 - 0.0062 16.6 0.1 0.036 14.2 0.1 2.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain MMR_HSR1 PF01926.23 EGG17961.1 - 0.0092 16.1 0.0 0.056 13.5 0.0 2.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SNF2_N PF00176.23 EGG17963.1 - 4.9e-69 232.7 0.1 8e-69 232.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG17963.1 - 5.9e-17 62.0 0.2 2.9e-16 59.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_6 PF14835.6 EGG17963.1 - 0.0023 17.7 2.1 0.0051 16.6 2.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 EGG17963.1 - 0.023 14.6 8.9 0.048 13.5 8.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG17963.1 - 0.52 10.2 8.5 1.2 9.1 8.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG17963.1 - 0.54 10.3 7.9 0.95 9.5 7.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGG17963.1 - 0.61 10.2 3.0 3.5 7.8 3.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGG17963.1 - 0.83 9.9 8.8 1.6 9.0 8.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DZR PF12773.7 EGG17963.1 - 1.3 9.1 3.4 7.3 6.7 3.4 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 EGG17963.1 - 1.5 8.7 5.9 2.6 8.0 5.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG17963.1 - 4.5 7.4 6.4 9.1 6.4 6.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger SPRY PF00622.28 EGG17964.1 - 6.4e-09 36.0 0.5 1.4e-08 34.8 0.2 1.7 2 0 0 2 2 2 1 SPRY domain PIG-X PF08320.12 EGG17965.1 - 8.8e-32 110.7 1.3 1.8e-30 106.5 1.3 2.3 1 1 0 1 1 1 1 PIG-X / PBN1 Pkinase_Tyr PF07714.17 EGG17966.1 - 1.6e-60 204.6 0.0 2.6e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG17966.1 - 1.4e-49 168.8 0.0 2.8e-49 167.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain ANAPC4_WD40 PF12894.7 EGG17966.1 - 5.2e-05 23.5 0.4 0.29 11.5 0.1 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_60s PF00428.19 EGG17967.1 - 2.1e-20 73.1 20.1 3.4e-20 72.4 20.1 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3682 PF12446.8 EGG17967.1 - 0.039 14.4 2.6 0.066 13.7 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) G-alpha PF00503.20 EGG17968.1 - 3.5e-101 338.9 0.5 4.5e-101 338.5 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGG17968.1 - 1.4e-16 60.4 0.6 1.1e-11 44.6 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG17968.1 - 6.3e-05 22.4 1.0 0.014 14.8 0.0 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGG17968.1 - 7e-05 23.0 0.3 0.28 11.4 0.1 2.7 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase CPT PF07931.12 EGG17968.1 - 0.025 14.4 0.0 0.067 13.0 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF3446 PF11928.8 EGG17969.1 - 0.027 14.8 22.9 0.14 12.5 3.8 3.5 3 0 0 3 3 3 0 Early growth response N-terminal domain TFIIA PF03153.13 EGG17969.1 - 7.3 6.5 49.9 0.26 11.2 36.2 2.9 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Coatomer_E PF04733.14 EGG17970.1 - 3.7e-78 262.9 12.4 3.7e-78 262.9 12.4 2.0 2 0 0 2 2 2 1 Coatomer epsilon subunit Pkinase PF00069.25 EGG17970.1 - 2e-42 145.4 0.1 2e-42 145.4 0.1 2.9 2 1 0 2 2 2 1 Protein kinase domain Ribonuc_2-5A PF06479.12 EGG17970.1 - 1.5e-38 131.8 0.3 1.5e-38 131.8 0.3 2.6 2 0 0 2 2 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EGG17970.1 - 1.2e-27 96.9 0.0 1.2e-27 96.9 0.0 2.0 2 0 0 2 2 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG17970.1 - 1.1e-06 28.2 0.0 1.1e-06 28.2 0.0 2.3 3 0 0 3 3 3 1 Kinase-like TPR_19 PF14559.6 EGG17970.1 - 1.3e-06 28.8 3.1 0.00047 20.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat PQQ_2 PF13360.6 EGG17970.1 - 3.9e-06 26.6 0.1 1.8e-05 24.4 0.1 2.0 1 1 1 2 2 2 1 PQQ-like domain TPR_12 PF13424.6 EGG17970.1 - 8.1e-05 22.8 4.7 0.015 15.6 0.1 4.6 5 1 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG17970.1 - 0.0016 18.6 11.6 0.021 15.0 0.1 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGG17970.1 - 0.0078 16.8 0.0 0.66 10.7 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG17970.1 - 0.014 15.4 9.2 2.4 8.5 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Glt_symporter PF03616.14 EGG17970.1 - 0.031 13.0 0.2 0.069 11.8 0.2 1.5 1 0 0 1 1 1 0 Sodium/glutamate symporter PQQ PF01011.21 EGG17970.1 - 0.033 14.1 0.3 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Kdo PF06293.14 EGG17970.1 - 0.035 13.5 2.6 0.35 10.2 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_1 PF00515.28 EGG17970.1 - 0.037 13.8 6.0 0.55 10.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PQQ_3 PF13570.6 EGG17970.1 - 0.13 12.8 0.1 7.4 7.2 0.0 3.3 4 0 0 4 4 4 0 PQQ-like domain Pex26 PF07163.12 EGG17970.1 - 1.7 7.9 9.3 11 5.2 0.2 2.7 2 0 0 2 2 2 0 Pex26 protein OATP PF03137.20 EGG17970.1 - 3.2 5.9 4.6 0.8 7.9 0.2 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cob_adeno_trans PF01923.18 EGG17971.1 - 1.3e-14 54.7 0.0 2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Cob_adeno_trans PF01923.18 EGG17972.1 - 4.1e-33 114.8 0.0 5.1e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase WD40 PF00400.32 EGG17974.1 - 1.8e-20 72.9 7.1 2.1e-05 25.2 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG17974.1 - 2.4e-07 31.0 0.1 0.69 10.2 0.0 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG17974.1 - 0.0029 16.6 0.5 1.9 7.4 0.0 3.6 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EGG17974.1 - 0.017 13.5 0.0 0.049 11.9 0.0 1.6 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz NUP214 PF16755.5 EGG17974.1 - 0.03 13.6 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 WD40_like PF17005.5 EGG17974.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain DUF5354 PF17305.2 EGG17974.1 - 0.088 13.0 0.2 0.25 11.6 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5354) Nup160 PF11715.8 EGG17974.1 - 0.34 9.5 2.9 6.9 5.2 0.1 2.7 1 1 2 3 3 3 0 Nucleoporin Nup120/160 DEAD PF00270.29 EGG17975.1 - 1.2e-39 135.9 0.3 2.9e-39 134.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG17975.1 - 2.2e-23 82.7 0.3 3.3e-22 78.9 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Microtub_bd PF16796.5 EGG17975.1 - 0.015 15.2 1.9 0.078 12.9 1.9 2.3 1 1 0 1 1 1 0 Microtubule binding Usher PF00577.20 EGG17975.1 - 0.045 12.6 0.1 0.045 12.6 0.1 2.2 2 0 0 2 2 2 0 Outer membrane usher protein DUF3246 PF11596.8 EGG17975.1 - 0.69 9.3 4.4 1.3 8.4 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) FAM176 PF14851.6 EGG17975.1 - 3 7.5 28.8 0.16 11.6 2.5 3.4 3 0 0 3 3 3 0 FAM176 family PPP4R2 PF09184.11 EGG17975.1 - 7.8 6.0 36.6 0.027 14.1 21.0 2.4 2 0 0 2 2 2 0 PPP4R2 RlaP PF10127.9 EGG17976.1 - 5.8e-33 114.5 1.0 2.4e-19 69.9 0.1 2.3 2 0 0 2 2 2 2 RNA repair pathway DNA polymerase beta family MRI PF15325.6 EGG17976.1 - 1.3 10.1 7.1 2.7 9.1 3.9 3.0 3 0 0 3 3 3 0 Modulator of retrovirus infection Cut8 PF08559.10 EGG17977.1 - 2e-38 132.4 11.8 2e-38 132.4 11.8 4.0 1 1 1 2 2 2 1 Cut8, nuclear proteasome tether protein BSP_II PF05432.11 EGG17978.1 - 0.00038 20.3 5.4 0.00039 20.2 5.4 1.0 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.10 EGG17978.1 - 0.00065 20.1 0.9 0.00085 19.7 0.9 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Myc_N PF01056.18 EGG17978.1 - 0.026 14.5 2.4 0.029 14.3 2.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Radial_spoke PF04712.12 EGG17978.1 - 0.048 12.6 4.9 0.055 12.4 4.9 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein DUF3377 PF11857.8 EGG17978.1 - 0.055 13.4 0.3 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF3169 PF11368.8 EGG17978.1 - 0.061 12.8 0.2 0.068 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) MscS_TM PF12794.7 EGG17978.1 - 0.15 10.9 1.7 0.19 10.6 1.7 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 GSK-3_bind PF05350.12 EGG17978.1 - 0.7 9.2 5.3 0.86 8.9 5.3 1.1 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding NOA36 PF06524.12 EGG17978.1 - 0.7 9.1 3.4 0.73 9.1 3.4 1.1 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.22 EGG17979.1 - 4e-29 100.2 0.0 3.3e-14 52.5 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrolase_6 PF13344.6 EGG17979.1 - 2.3e-21 75.8 0.1 1.1e-20 73.5 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGG17979.1 - 3.4e-15 55.9 0.0 7.4e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like RRM_7 PF16367.5 EGG17979.1 - 0.069 13.3 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif UFD1 PF03152.14 EGG17979.1 - 0.074 12.5 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 RRM_5 PF13893.6 EGG17979.1 - 0.075 12.6 0.0 1.1 8.9 0.0 2.5 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Drf_FH1 PF06346.12 EGG17979.1 - 0.81 9.4 41.3 1.3 8.7 41.3 1.2 1 0 0 1 1 1 0 Formin Homology Region 1 zf-CDGSH PF09360.10 EGG17980.1 - 2.3e-22 79.0 4.1 8.5e-11 41.9 0.1 2.4 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type MSL2-CXC PF16682.5 EGG17980.1 - 0.044 13.9 4.5 0.44 10.7 0.4 2.3 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 WD40 PF00400.32 EGG17981.1 - 4.3e-31 106.5 23.3 1.2e-05 25.9 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.12 EGG17981.1 - 1.3e-20 73.6 0.0 2.5e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 EGG17981.1 - 1.8e-09 37.8 5.0 2.5e-05 24.5 0.5 4.0 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG17981.1 - 1.7e-05 24.0 2.4 0.029 13.3 1.4 3.8 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGG17981.1 - 0.11 11.1 13.9 0.086 11.5 0.6 4.0 1 1 3 4 4 4 0 Nucleoporin Nup120/160 Myb_DNA-binding PF00249.31 EGG17982.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain ABC_tran PF00005.27 EGG17983.1 - 5.6e-23 82.0 0.0 5e-20 72.4 0.0 2.7 1 1 0 1 1 1 1 ABC transporter CBM49 PF09478.10 EGG17983.1 - 6.5e-16 58.4 0.8 1.6e-15 57.2 0.1 2.1 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 GSH-S_ATP PF02955.16 EGG17984.1 - 0.00035 20.0 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain CH PF00307.31 EGG17985.1 - 1.3e-30 105.8 16.5 1.2e-15 57.6 0.2 4.4 4 1 1 5 5 5 2 Calponin homology (CH) domain FAM76 PF16046.5 EGG17985.1 - 0.00065 19.2 7.3 0.00065 19.2 7.3 8.3 3 1 3 7 7 7 1 FAM76 protein CAMSAP_CH PF11971.8 EGG17985.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain DUF3460 PF11943.8 EGG17985.1 - 4.3 7.7 11.5 4.6 7.6 1.4 4.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3460) ABC_membrane PF00664.23 EGG17986.1 - 6.9e-52 176.8 11.1 6.9e-52 176.8 11.1 1.6 2 0 0 2 2 1 1 ABC transporter transmembrane region Dicty_spore_N PF04562.12 EGG17986.1 - 1.9e-46 157.5 68.9 2.9e-27 95.6 20.7 4.5 4 1 0 4 4 3 3 Dictyostelium spore coat protein, N terminus ABC_tran PF00005.27 EGG17986.1 - 5.7e-33 114.3 0.2 2.9e-32 112.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGG17986.1 - 8.7e-09 35.1 0.2 8.7e-09 35.1 0.2 1.5 2 0 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGG17986.1 - 0.011 16.0 0.1 0.065 13.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 EGG17986.1 - 0.013 15.3 0.0 0.057 13.2 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EGG17986.1 - 0.019 14.7 0.2 0.14 11.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGG17986.1 - 0.04 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EGG17986.1 - 0.042 14.3 0.5 0.72 10.3 0.7 2.6 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGG17986.1 - 0.05 13.2 0.0 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGG17986.1 - 0.095 12.6 0.9 0.24 11.3 0.0 2.2 2 0 0 2 2 1 0 RsgA GTPase Zeta_toxin PF06414.12 EGG17986.1 - 0.1 11.8 0.3 0.51 9.6 0.0 2.2 3 0 0 3 3 3 0 Zeta toxin AAA_18 PF13238.6 EGG17986.1 - 0.2 12.2 2.2 0.51 10.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.9 EGG17986.1 - 5.8 5.3 11.7 0.52 8.8 5.0 2.0 2 0 0 2 2 2 0 Macoilin family DAO PF01266.24 EGG17987.1 - 5.2e-43 148.0 0.0 6e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGG17987.1 - 1.7e-09 37.3 0.0 2.8e-05 23.4 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EGG17987.1 - 1.1e-08 34.2 0.5 0.0025 16.6 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 EGG17987.1 - 2.6e-08 33.4 0.3 5e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EGG17987.1 - 1.6e-06 27.6 5.1 4.5e-06 26.1 0.4 2.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG17987.1 - 4.4e-06 26.8 0.1 1.1e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGG17987.1 - 1.1e-05 24.9 0.1 2.7e-05 23.6 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EGG17987.1 - 1.5e-05 24.4 0.1 3.6e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EGG17987.1 - 0.00014 21.4 0.0 0.00039 19.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGG17987.1 - 0.00063 19.1 0.1 0.81 8.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 EGG17987.1 - 0.0015 17.2 0.3 0.052 12.1 0.1 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor Pyr_redox PF00070.27 EGG17987.1 - 0.0045 17.5 0.3 0.061 13.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EGG17987.1 - 0.016 15.1 1.3 0.018 14.9 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EGG17987.1 - 0.029 13.4 0.0 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein GMC_oxred_N PF00732.19 EGG17987.1 - 0.047 13.0 0.0 5.6 6.2 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Amino_oxidase PF01593.24 EGG17987.1 - 0.15 11.4 0.2 0.94 8.7 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase SpoVT_C PF15714.5 EGG17987.1 - 0.28 11.2 1.5 0.77 9.8 0.0 2.2 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor POP1 PF06978.11 EGG17988.1 - 6.6e-33 114.4 30.5 3.6e-20 72.8 3.6 3.8 3 1 1 4 4 4 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EGG17988.1 - 2.7e-26 91.7 0.1 2.7e-26 91.7 0.1 2.9 3 0 0 3 3 3 1 POPLD (NUC188) domain GCV_T PF01571.21 EGG17988.1 - 0.00058 19.3 0.0 0.11 11.8 0.0 2.9 3 0 0 3 3 3 1 Aminomethyltransferase folate-binding domain Barttin PF15462.6 EGG17988.1 - 0.02 14.7 0.1 0.048 13.4 0.1 1.6 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DUF4194 PF13835.6 EGG17988.1 - 0.91 9.2 4.8 5.5 6.7 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4194) YqfQ PF14181.6 EGG17988.1 - 1.9 8.7 6.0 3.4 7.8 4.6 2.2 2 0 0 2 2 2 0 YqfQ-like protein CHCH PF06747.13 EGG17989.1 - 8e-05 22.7 0.7 0.00012 22.1 0.7 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EGG17989.1 - 0.00011 22.1 0.2 0.00018 21.4 0.2 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MTCP1 PF08991.10 EGG17989.1 - 0.0098 16.1 0.7 0.015 15.5 0.7 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Cmc1 PF08583.10 EGG17989.1 - 0.068 13.2 1.1 0.13 12.3 1.1 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 EGG17989.1 - 0.087 12.6 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) SR-25 PF10500.9 EGG17990.1 - 0.15 11.7 14.6 0.14 11.8 13.2 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SUIM_assoc PF16619.5 EGG17990.1 - 5.9 7.0 13.6 0.37 10.9 1.7 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 RNA_pol_L_2 PF13656.6 EGG17991.1 - 2.6e-25 88.0 0.8 1.7e-24 85.4 0.1 2.9 4 0 0 4 4 4 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Dynamin_N PF00350.23 EGG17991.1 - 5.2e-05 23.4 0.1 5.2e-05 23.4 0.1 3.6 4 1 0 4 4 4 1 Dynamin family RNA_pol_L PF01193.24 EGG17991.1 - 0.00018 20.9 0.0 0.00075 18.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cyclin_N PF00134.23 EGG17994.1 - 2e-35 121.3 0.9 2.8e-34 117.6 0.2 2.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGG17994.1 - 3.8e-20 72.2 0.4 3.1e-19 69.2 0.0 2.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Zip PF02535.22 EGG17994.1 - 3.9 6.6 26.9 0.33 10.1 3.9 2.6 2 0 0 2 2 2 0 ZIP Zinc transporter SAP PF02037.27 EGG17996.1 - 4e-06 26.4 4.4 6.5e-06 25.8 0.2 2.6 2 1 0 2 2 2 1 SAP domain DUF3439 PF11921.8 EGG17996.1 - 0.33 10.9 9.7 0.87 9.6 9.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NPC1_N PF16414.5 EGG17997.1 - 0.037 13.6 0.1 0.037 13.6 0.1 1.0 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus ABC_membrane PF00664.23 EGG17998.1 - 3e-67 227.2 45.0 9.2e-38 130.4 15.2 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGG17998.1 - 3.5e-51 173.3 8.1 1.6e-28 99.9 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EGG17998.1 - 5.7e-08 32.5 7.5 0.011 15.2 1.0 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGG17998.1 - 2e-07 31.1 0.3 0.027 14.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG17998.1 - 1.2e-05 25.3 0.8 0.011 15.6 0.3 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGG17998.1 - 1.9e-05 25.1 0.1 0.12 12.7 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGG17998.1 - 3.5e-05 23.4 0.4 0.2 11.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 EGG17998.1 - 0.0013 18.3 0.6 0.78 9.2 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 EGG17998.1 - 0.0021 18.3 0.9 2.2 8.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain FKBP_N_2 PF18023.1 EGG17998.1 - 0.0033 17.5 0.5 0.0085 16.2 0.5 1.6 1 0 0 1 1 1 1 BDBT FKBP like N-terminal DUF815 PF05673.13 EGG17998.1 - 0.0046 16.1 0.3 1.5 7.9 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EGG17998.1 - 0.0072 15.6 0.5 1.1 8.5 0.2 2.5 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 EGG17998.1 - 0.0074 16.5 1.6 2.9 8.1 0.0 3.0 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 EGG17998.1 - 0.023 13.8 0.1 4.5 6.2 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 EGG17998.1 - 0.028 14.2 0.1 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain MTABC_N PF16185.5 EGG17998.1 - 0.029 13.9 9.0 0.13 11.8 9.0 2.2 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region RNA_helicase PF00910.22 EGG17998.1 - 0.034 14.5 0.1 8.9 6.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 EGG17998.1 - 0.037 14.0 0.2 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 EGG17998.1 - 0.043 12.8 1.3 5.6 5.9 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 EGG17998.1 - 0.046 13.8 11.5 0.39 10.8 0.3 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain TsaE PF02367.17 EGG17998.1 - 0.049 13.6 0.1 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGG17998.1 - 0.077 12.4 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 EGG17998.1 - 0.079 12.1 0.8 12 5.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 EGG17998.1 - 0.095 12.8 13.9 6.7 6.7 10.3 3.5 2 1 0 2 2 2 0 Dynamin family Sigma54_activat PF00158.26 EGG17998.1 - 0.1 12.3 0.1 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain PduV-EutP PF10662.9 EGG17998.1 - 0.11 12.2 0.2 3.8 7.3 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 EGG17998.1 - 0.13 11.8 0.1 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EGG17998.1 - 0.15 11.9 0.1 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 EGG17998.1 - 0.47 10.9 16.2 2.3 8.7 0.1 3.5 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EGG17998.1 - 0.91 10.1 4.1 13 6.3 0.1 3.0 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.6 EGG17998.1 - 2.1 8.1 9.0 0.86 9.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MGC-24 PF05283.11 EGG17998.1 - 7.3 7.0 6.4 0.6 10.5 0.1 2.3 3 0 0 3 3 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PfkB PF00294.24 EGG17999.1 - 3.3e-13 49.6 0.3 3.6e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Transposase_24 PF03004.14 EGG17999.1 - 0.0052 16.9 2.2 0.014 15.5 2.2 1.6 1 0 0 1 1 1 1 Plant transposase (Ptta/En/Spm family) ABC_membrane PF00664.23 EGG18000.1 - 1.3e-49 169.4 34.0 2.5e-30 106.1 11.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGG18000.1 - 2.1e-47 161.1 3.4 1e-27 97.3 0.0 2.9 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 EGG18000.1 - 2.6e-10 40.1 13.8 0.00099 18.6 0.3 4.6 3 2 0 5 5 5 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGG18000.1 - 1.7e-05 24.8 1.2 0.06 13.2 0.3 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGG18000.1 - 0.00056 19.6 4.6 0.12 12.2 0.9 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGG18000.1 - 0.0011 19.0 1.4 0.65 10.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGG18000.1 - 0.035 14.5 0.2 14 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 EGG18000.1 - 0.11 12.2 17.5 0.35 10.6 0.5 4.4 5 1 1 6 6 6 0 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 EGG18000.1 - 0.4 10.7 9.3 0.45 10.5 0.2 3.7 3 0 0 3 3 3 0 Dynamin family AAA_22 PF13401.6 EGG18000.1 - 1 9.7 2.7 11 6.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain KA1 PF02149.19 EGG18001.1 - 1.3e-17 63.3 0.1 2e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 DUF2052 PF09747.9 EGG18001.1 - 0.0013 18.9 0.7 0.0013 18.9 0.7 3.2 3 1 0 3 3 3 1 Coiled-coil domain containing protein (DUF2052) GXGXG PF01493.19 EGG18001.1 - 0.029 14.0 0.1 0.082 12.5 0.1 1.7 2 0 0 2 2 2 0 GXGXG motif Pkinase PF00069.25 EGG18002.1 - 4.3e-63 213.1 0.1 4.3e-63 213.1 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG18002.1 - 2e-39 135.5 0.0 3.4e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M16 PF00675.20 EGG18002.1 - 5.9e-25 88.0 0.0 1.6e-24 86.6 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGG18002.1 - 1.4e-08 35.0 0.0 4.2e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Peptidase M16 inactive domain RIO1 PF01163.22 EGG18002.1 - 1.4e-06 28.0 0.6 4e-05 23.3 0.2 2.5 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 EGG18002.1 - 0.00016 20.8 1.9 0.00016 20.8 1.9 2.6 2 1 1 3 3 3 1 Haspin like kinase domain APH PF01636.23 EGG18002.1 - 0.00019 21.4 0.0 0.0029 17.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG18002.1 - 0.0048 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG18002.1 - 0.0066 15.8 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Presenilin PF01080.17 EGG18003.1 - 2e-127 425.3 15.2 2.2e-83 280.2 12.8 2.3 2 1 1 3 3 3 2 Presenilin UPF0242 PF06785.11 EGG18003.1 - 9.7 6.2 16.1 4.2 7.4 0.3 3.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CBFD_NFYB_HMF PF00808.23 EGG18004.1 - 3.2e-16 59.3 0.4 5.4e-16 58.6 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SDA1 PF05285.12 EGG18004.1 - 0.0049 16.4 7.5 0.0049 16.4 7.5 2.1 2 0 0 2 2 2 1 SDA1 MIP-T3 PF10243.9 EGG18004.1 - 0.067 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH-like domain Acetyltransf_19 PF18015.1 EGG18008.1 - 0.0022 18.2 1.3 0.0026 18.0 1.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Kelch_1 PF01344.25 EGG18009.1 - 3.1e-42 141.9 10.7 3.5e-11 42.5 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EGG18009.1 - 9.4e-40 133.6 12.3 3.1e-10 40.0 0.0 6.6 4 1 2 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EGG18009.1 - 1.1e-32 111.5 5.6 2.8e-05 24.0 0.0 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGG18009.1 - 2e-32 109.9 7.2 6.9e-09 35.3 0.1 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EGG18009.1 - 3.1e-32 110.3 14.3 3.1e-09 36.7 0.1 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGG18009.1 - 1.1e-23 83.0 11.7 6.3e-08 32.7 0.1 7.8 7 0 0 7 7 7 4 Galactose oxidase, central domain F-box PF00646.33 EGG18009.1 - 1.3e-07 31.3 6.8 8.3e-06 25.5 0.3 3.2 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.7 EGG18009.1 - 1.2e-06 28.3 0.0 3.8e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EGG18009.1 - 0.001 18.9 0.0 0.0034 17.2 0.0 1.9 1 0 0 1 1 1 1 F-box YMF19 PF02326.15 EGG18009.1 - 0.0014 19.3 1.4 0.0014 19.3 1.4 4.7 3 1 1 4 4 4 1 Plant ATP synthase F0 DUF1631 PF07793.11 EGG18009.1 - 2.3 6.6 4.5 3.4 6.0 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) HGTP_anticodon PF03129.20 EGG18010.1 - 1.6e-23 82.7 0.2 3.4e-22 78.4 0.1 2.5 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGG18010.1 - 2e-09 37.7 0.0 6.6e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) SasG_E PF17041.5 EGG18010.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 E domain DPBB_1 PF03330.18 EGG18011.1 - 6e-06 26.5 2.9 6e-05 23.2 1.6 2.8 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 EGG18011.1 - 0.027 14.3 1.1 0.045 13.6 0.0 1.9 2 0 0 2 2 2 0 Barwin family Abhydrolase_6 PF12697.7 EGG18012.1 - 2.7e-16 60.8 0.2 3.2e-16 60.6 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EGG18012.1 - 1.1e-05 25.4 0.0 2.4e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_1 PF00561.20 EGG18012.1 - 8.4e-05 22.3 0.2 0.0011 18.7 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG18012.1 - 0.0056 16.0 0.1 0.12 11.6 0.0 2.6 2 1 1 3 3 3 1 Serine aminopeptidase, S33 VirJ PF06057.11 EGG18012.1 - 0.12 12.2 0.1 0.91 9.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) MIT PF04212.18 EGG18013.1 - 6.9e-27 93.3 9.3 3.7e-15 55.7 1.9 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain LIM PF00412.22 EGG18013.1 - 2.4e-08 34.1 0.4 6.1e-06 26.4 0.1 2.4 1 1 1 2 2 2 2 LIM domain Arrestin_C PF02752.22 EGG18013.1 - 0.00027 21.4 5.3 0.00051 20.5 0.0 3.0 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain MG2 PF01835.19 EGG18013.1 - 0.0034 17.8 0.8 0.019 15.4 0.0 2.3 2 0 0 2 2 2 1 MG2 domain SUIM_assoc PF16619.5 EGG18013.1 - 0.0068 16.4 5.3 0.019 15.0 5.3 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Pol_alpha_B_N PF08418.10 EGG18013.1 - 0.03 14.3 0.9 0.03 14.3 0.9 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal TPR_8 PF13181.6 EGG18013.1 - 0.93 9.9 7.5 5.5 7.5 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIIA PF03153.13 EGG18013.1 - 1.1 9.2 14.5 1.8 8.5 14.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_2 PF07719.17 EGG18013.1 - 8.6 6.8 7.6 2.8 8.3 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CCDC53 PF10152.9 EGG18014.1 - 2.5e-42 144.9 0.0 2.5e-42 144.9 0.0 3.4 2 2 0 2 2 2 1 Subunit CCDC53 of WASH complex SURF2 PF05477.11 EGG18014.1 - 7.7 6.1 8.5 13 5.4 8.5 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) ubiquitin PF00240.23 EGG18015.1 - 2.5e-20 72.0 0.2 4.5e-20 71.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EGG18015.1 - 9.3e-08 31.8 1.7 2.2e-07 30.7 0.1 2.6 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 EGG18015.1 - 2e-07 30.8 0.1 3.5e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 EGG18015.1 - 4.6e-05 23.3 43.2 0.0069 16.3 8.7 5.1 2 2 2 4 4 4 3 STI1 domain Ubiquitin_2 PF14560.6 EGG18015.1 - 0.00057 20.3 0.1 0.0017 18.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain LPD22 PF18834.1 EGG18015.1 - 0.011 15.9 3.4 1.6 9.0 0.0 2.9 3 0 0 3 3 2 0 Large polyvalent protein associated domain 22 CUE PF02845.16 EGG18015.1 - 0.012 15.3 1.1 0.034 13.9 0.0 2.4 2 0 0 2 2 2 0 CUE domain HOIP-UBA PF16678.5 EGG18015.1 - 0.021 14.8 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 HOIP UBA domain pair RsmJ PF04378.13 EGG18015.1 - 0.17 11.1 0.2 0.27 10.4 0.2 1.3 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ BSD PF03909.17 EGG18015.1 - 4.3 7.4 5.0 21 5.2 0.2 3.7 2 2 1 3 3 3 0 BSD domain Com_YlbF PF06133.11 EGG18015.1 - 5.7 7.6 10.8 1.2 9.8 0.4 3.3 2 2 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA GerD PF17898.1 EGG18015.1 - 6.2 6.8 20.5 1.1 9.2 5.7 3.7 2 1 2 4 4 4 0 Spore germination GerD central core domain HARP PF07443.13 EGG18016.1 - 0.089 12.5 0.1 2 8.1 0.1 2.5 2 0 0 2 2 2 0 HepA-related protein (HARP) VASt PF16016.5 EGG18017.1 - 5.2e-33 114.6 2.5 1.3e-32 113.3 2.5 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EGG18017.1 - 2.3e-18 66.1 2.2 4.4e-18 65.2 0.9 2.1 2 0 0 2 2 2 1 GRAM domain Pkinase PF00069.25 EGG18019.1 - 7.5e-71 238.6 0.0 1.9e-70 237.3 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG18019.1 - 1.7e-52 178.3 0.0 3.2e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGEF PF00621.20 EGG18019.1 - 7.7e-45 153.4 1.3 3.9e-44 151.1 1.3 2.4 1 0 0 1 1 1 1 RhoGEF domain Ion_trans PF00520.31 EGG18019.1 - 5.2e-07 29.1 13.8 1e-06 28.2 13.8 1.4 1 0 0 1 1 1 1 Ion transport protein Pkinase_fungal PF17667.1 EGG18019.1 - 1e-05 24.5 0.1 1e-05 24.5 0.1 4.2 4 1 1 5 5 5 1 Fungal protein kinase PH PF00169.29 EGG18019.1 - 0.00065 20.2 1.6 0.012 16.1 0.0 3.2 3 0 0 3 3 3 1 PH domain PBD PF00786.28 EGG18019.1 - 0.0053 17.1 2.5 0.0061 16.9 0.3 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 EGG18019.1 - 0.0067 15.8 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like AAA_25 PF13481.6 EGG18019.1 - 0.015 14.9 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain HEAT_EZ PF13513.6 EGG18020.1 - 1.6e-05 25.3 0.0 0.11 13.0 0.0 3.3 3 0 0 3 3 3 2 HEAT-like repeat Tti2 PF10521.9 EGG18020.1 - 2.5e-05 24.0 0.4 0.13 11.8 0.1 2.8 2 0 0 2 2 2 2 Tti2 family Vac14_Fab1_bd PF12755.7 EGG18020.1 - 5.1e-05 23.8 0.2 0.95 10.1 0.1 3.4 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGG18020.1 - 6.3e-05 22.9 0.5 0.035 14.4 0.1 3.1 2 0 0 2 2 2 1 HEAT repeat RRN3 PF05327.11 EGG18020.1 - 0.0031 16.2 17.7 0.22 10.0 0.0 3.3 3 0 0 3 3 3 2 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 EGG18020.1 - 0.0036 16.8 13.3 0.0064 16.0 13.3 1.3 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 EGG18020.1 - 0.0093 14.3 15.1 0.014 13.7 15.1 1.2 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 EGG18020.1 - 0.016 14.6 10.5 0.025 13.9 10.5 1.2 1 0 0 1 1 1 0 BUD22 HEAT_2 PF13646.6 EGG18020.1 - 0.027 14.9 0.0 18 5.8 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats DNA_pol_phi PF04931.13 EGG18020.1 - 0.027 12.6 21.4 0.06 11.5 21.4 1.6 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 EGG18020.1 - 0.095 11.9 11.8 0.075 12.2 9.8 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF3452 PF11934.8 EGG18020.1 - 0.13 11.8 4.0 0.19 11.3 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3452) YL1 PF05764.13 EGG18020.1 - 0.17 12.0 14.8 0.33 11.0 14.8 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 EGG18020.1 - 0.28 9.3 19.5 0.021 13.1 14.6 1.6 2 0 0 2 2 2 0 Nop14-like family FAM60A PF15396.6 EGG18020.1 - 1.5 8.8 6.1 3 7.8 6.1 1.5 1 0 0 1 1 1 0 Protein Family FAM60A DUF2457 PF10446.9 EGG18020.1 - 2.6 7.1 26.7 5.1 6.1 26.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LRR_8 PF13855.6 EGG18021.1 - 0.14 11.9 0.8 0.88 9.4 0.2 2.7 3 1 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 EGG18021.1 - 0.19 11.9 3.8 57 4.1 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat DUF3430 PF11912.8 EGG18022.1 - 0.00029 20.9 26.6 0.00029 20.9 26.6 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGG18022.1 - 0.69 10.2 6.7 0.31 11.3 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) FNIP PF05725.12 EGG18023.1 - 0.0021 18.2 18.4 0.076 13.2 0.5 5.4 4 2 1 5 5 5 3 FNIP Repeat LRR_1 PF00560.33 EGG18023.1 - 0.01 16.2 2.9 52 5.0 0.0 5.3 4 1 1 5 5 5 0 Leucine Rich Repeat CBM49 PF09478.10 EGG18024.1 - 2.7e-14 53.3 0.3 3.7e-14 52.8 0.3 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Myb_DNA-binding PF00249.31 EGG18025.1 - 2.6e-13 49.9 0.2 1.4e-05 25.2 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG18025.1 - 3.9e-05 23.8 3.6 0.0051 17.0 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain YfiO PF13525.6 EGG18025.1 - 0.0072 16.1 0.2 3.3 7.4 0.0 2.2 2 0 0 2 2 2 2 Outer membrane lipoprotein HTH_AsnC-type PF13404.6 EGG18025.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Beach PF02138.18 EGG18026.1 - 4.5e-118 393.6 0.1 1.2e-117 392.2 0.1 1.8 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EGG18026.1 - 1.2e-17 64.0 16.1 0.0052 17.6 1.8 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG18026.1 - 4.1e-13 49.4 0.3 0.045 14.1 0.0 5.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PH_BEACH PF14844.6 EGG18026.1 - 3.5e-11 43.1 4.2 1.3e-09 38.0 0.5 4.2 3 2 0 3 3 3 1 PH domain associated with Beige/BEACH WD40_like PF17005.5 EGG18026.1 - 7.3e-11 41.9 8.4 6.6e-08 32.2 0.6 2.4 2 0 0 2 2 2 2 WD40-like domain GRAM PF02893.20 EGG18026.1 - 4.7e-09 36.1 0.4 1.4e-06 28.2 0.2 2.8 2 0 0 2 2 2 2 GRAM domain bPH_3 PF14470.6 EGG18026.1 - 0.024 15.0 0.0 0.41 11.0 0.0 2.7 2 0 0 2 2 2 0 Bacterial PH domain BBS2_Mid PF14783.6 EGG18026.1 - 0.029 14.4 0.9 0.81 9.8 0.0 3.7 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region LRR_9 PF14580.6 EGG18027.1 - 6.1e-63 211.5 6.6 8.1e-63 211.1 6.6 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGG18027.1 - 4.1e-09 36.6 24.4 0.00013 22.2 6.2 4.9 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG18027.1 - 5.4e-06 26.1 5.6 5.4e-06 26.1 5.6 3.9 4 1 0 4 4 4 2 Leucine rich repeat UB2H PF14814.6 EGG18027.1 - 0.057 13.4 0.2 14 5.8 0.0 3.7 1 1 3 4 4 4 0 Bifunctional transglycosylase second domain GATase PF00117.28 EGG18028.1 - 1.5e-07 31.4 0.0 3.6e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I HTS PF04204.16 EGG18028.1 - 0.013 14.4 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Homoserine O-succinyltransferase DUF4064 PF13273.6 EGG18028.1 - 0.029 14.6 0.0 0.029 14.6 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Claudin_2 PF13903.6 EGG18028.1 - 4.4 7.0 10.8 12 5.6 0.2 2.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction La PF05383.17 EGG18030.1 - 9.5e-19 67.2 2.2 2.8e-18 65.7 2.2 1.9 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EGG18030.1 - 7.9e-14 51.2 0.4 3.4e-10 39.6 0.0 3.5 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTS_2-RNA PF01885.16 EGG18030.1 - 0.00043 20.4 0.3 0.00043 20.4 0.3 1.9 3 0 0 3 3 3 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RRM_3 PF08777.11 EGG18030.1 - 0.00049 20.1 6.3 0.1 12.7 2.2 3.3 3 1 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.6 EGG18030.1 - 0.064 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif YoaP PF14268.6 EGG18030.1 - 0.52 9.9 4.2 3.1 7.4 0.1 3.6 3 1 0 3 3 3 0 YoaP-like F-box PF00646.33 EGG18031.1 - 0.029 14.3 0.5 0.2 11.6 0.5 2.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EGG18031.1 - 0.53 10.2 5.0 0.19 11.7 1.0 2.3 2 0 0 2 2 2 0 F-box-like ATP-synt PF00231.19 EGG18032.1 - 2.5e-59 201.3 0.8 3.7e-59 200.7 0.8 1.2 1 0 0 1 1 1 1 ATP synthase Ank_2 PF12796.7 EGG18033.1 - 0.01 16.4 0.0 0.58 10.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) DUF2857 PF11198.8 EGG18033.1 - 0.057 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) DUF5589 PF17672.1 EGG18034.1 - 0.37 10.7 2.2 0.82 9.6 2.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5589) Ribosomal_L27 PF01016.19 EGG18035.1 - 1.9e-34 117.5 0.4 2.3e-34 117.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein LRR_8 PF13855.6 EGG18040.1 - 0.0037 17.0 2.5 0.03 14.1 0.3 3.3 3 1 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 EGG18040.1 - 0.22 11.7 8.7 9.3 6.6 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat DUF1645 PF07816.11 EGG18040.1 - 0.28 11.8 8.9 0.35 11.4 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Glft2_N PF17994.1 EGG18041.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Galactofuranosyltransferase 2 N-terminal DUF2647 PF10839.8 EGG18042.1 - 0.0084 16.1 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2647) CRAL_TRIO_2 PF13716.6 EGG18042.1 - 0.021 15.0 0.1 0.025 14.7 0.1 1.3 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain GP40 PF11025.8 EGG18042.1 - 0.058 13.2 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium DUF4667 PF15700.5 EGG18044.1 - 0.014 15.5 9.5 0.38 10.8 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Rol_Rep_N PF18106.1 EGG18044.1 - 0.017 15.4 0.0 10 6.5 0.0 3.0 2 0 0 2 2 2 0 Rolling Circle replication initiation protein N-terminal domain RL11D PF11088.8 EGG18044.1 - 0.33 11.3 4.0 18 5.7 0.3 3.0 2 0 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 DUF508 PF04370.12 EGG18044.1 - 4 7.2 12.5 16 5.2 6.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF508) RTBV_P12 PF06361.11 EGG18046.1 - 0.79 10.1 4.6 0.47 10.9 2.0 1.8 1 1 1 2 2 2 0 Rice tungro bacilliform virus P12 protein DUF3430 PF11912.8 EGG18049.1 - 1.3e-24 87.4 17.7 1.6e-24 87.2 17.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) CHAT PF12770.7 EGG18051.1 - 3.2e-37 128.5 0.0 2.3e-36 125.7 0.0 2.0 2 0 0 2 2 2 1 CHAT domain TPR_2 PF07719.17 EGG18051.1 - 0.00023 21.0 3.3 10 6.5 0.7 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF5133 PF17196.4 EGG18051.1 - 0.13 12.4 0.0 34 4.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) CBM_5_12_2 PF14600.6 EGG18051.1 - 0.15 12.0 3.1 5.1 7.1 0.4 2.8 2 0 0 2 2 2 0 Cellulose-binding domain TPR_8 PF13181.6 EGG18051.1 - 1.9 8.9 7.1 14 6.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat CHAT PF12770.7 EGG18052.1 - 2.4e-23 83.0 0.0 3.9e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 CHAT domain DUF2484 PF10658.9 EGG18055.1 - 0.49 10.7 9.5 0.31 11.4 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) CHAT PF12770.7 EGG18056.1 - 1e-48 166.2 0.0 2.3e-48 165.1 0.0 1.6 1 0 0 1 1 1 1 CHAT domain CENP-B_dimeris PF09026.10 EGG18056.1 - 0.72 10.3 4.1 3.1 8.3 3.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CHAT PF12770.7 EGG18057.1 - 2.8e-48 164.8 0.1 6.4e-48 163.6 0.0 1.6 2 0 0 2 2 2 1 CHAT domain DUF4746 PF15928.5 EGG18057.1 - 0.0032 17.0 2.8 0.0032 17.0 2.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4746) TPR_2 PF07719.17 EGG18057.1 - 0.082 13.1 2.7 26 5.3 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5421 PF17458.2 EGG18057.1 - 0.64 9.4 12.2 0.22 10.9 9.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5421) BUD22 PF09073.10 EGG18057.1 - 2 7.7 16.4 0.98 8.7 2.0 2.3 2 0 0 2 2 2 0 BUD22 SIR2 PF02146.17 EGG18058.1 - 1.8e-25 89.9 0.0 3.3e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Pkinase_Tyr PF07714.17 EGG18058.1 - 2.4e-09 36.8 0.1 3.9e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG18058.1 - 4.7e-09 36.0 0.2 7.1e-09 35.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Aa_trans PF01490.18 EGG18059.1 - 1.1e-09 37.5 31.5 1.8e-09 36.8 31.5 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGG18059.1 - 0.0014 17.7 16.9 0.0014 17.7 16.9 2.3 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family CBM49 PF09478.10 EGG18060.1 - 5e-13 49.2 0.2 1.4e-12 47.7 0.2 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Inhibitor_I29 PF08246.12 EGG18063.1 - 4.7e-09 36.5 0.0 9.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) EphA2_TM PF14575.6 EGG18063.1 - 0.039 14.8 0.1 0.34 11.8 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3896 PF13035.6 EGG18063.1 - 0.096 12.9 0.2 0.18 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) DUF4930 PF16284.5 EGG18063.1 - 0.13 12.2 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4930) Peptidase_C1 PF00112.23 EGG18064.1 - 4.8e-45 154.3 0.7 4.8e-45 154.3 0.7 1.5 2 0 0 2 2 2 1 Papain family cysteine protease CAP PF00188.26 EGG18064.1 - 2.3e-06 28.5 0.7 6.2e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Nucleo_P87 PF07267.11 EGG18064.1 - 0.058 12.2 2.9 0.069 12.0 2.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Trypan_PARP PF05887.11 EGG18064.1 - 0.069 13.1 9.0 0.11 12.4 9.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4106 PF13388.6 EGG18064.1 - 0.31 10.2 10.8 0.46 9.6 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) MGC-24 PF05283.11 EGG18064.1 - 5.9 7.3 8.8 14 6.1 8.8 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 EGG18064.1 - 9.1 6.3 26.5 17 5.4 26.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein CBM49 PF09478.10 EGG18065.1 - 1.8e-13 50.6 0.2 2.5e-13 50.1 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF4269 PF14091.6 EGG18066.1 - 0.027 14.7 1.0 0.074 13.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) MdcG PF10620.9 EGG18066.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG CCDC106 PF15794.5 EGG18066.1 - 4.7 6.9 9.0 2 8.0 1.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 CBM49 PF09478.10 EGG18067.1 - 1.8e-13 50.6 0.2 2.5e-13 50.1 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 BOP1NT PF08145.12 EGG18068.1 - 1.4e-91 307.0 7.5 1.4e-91 307.0 7.5 1.8 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 EGG18068.1 - 3.7e-22 78.2 8.5 1.5e-08 35.2 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG18068.1 - 5.5e-09 36.2 1.0 1.3e-05 25.4 0.1 4.1 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGG18068.1 - 0.0037 16.4 1.6 0.19 10.8 0.2 2.3 1 1 1 2 2 2 2 Coatomer WD associated region Vps16_N PF04841.13 EGG18068.1 - 0.0053 15.6 0.0 0.024 13.4 0.0 1.8 2 0 0 2 2 2 1 Vps16, N-terminal region DUF1513 PF07433.11 EGG18068.1 - 0.0087 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1513) Rav1p_C PF12234.8 EGG18068.1 - 0.011 14.2 0.0 0.018 13.5 0.0 1.3 1 0 0 1 1 1 0 RAVE protein 1 C terminal NHL PF01436.21 EGG18068.1 - 0.035 14.1 0.1 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 NHL repeat GCV_H PF01597.19 EGG18069.1 - 1.1e-06 28.6 0.0 2.6e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Glycine cleavage H-protein DUF2798 PF11391.8 EGG18070.1 - 0.2 11.7 1.8 1.8 8.7 1.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2798) G-alpha PF00503.20 EGG18071.1 - 4.6e-67 226.7 18.7 2.2e-41 142.2 4.8 2.8 2 1 1 3 3 3 2 G-protein alpha subunit Arf PF00025.21 EGG18071.1 - 1.8e-07 30.8 4.4 0.0016 17.9 0.3 3.6 3 1 0 3 3 3 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG18071.1 - 0.062 13.4 1.2 1.5 9.0 1.2 2.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase SWI-SNF_Ssr4 PF08549.10 EGG18071.1 - 9.2 4.8 11.8 0.057 12.0 3.2 1.6 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Dicty_CAD PF05720.12 EGG18072.1 - 2.8e-12 46.4 0.1 1.1e-11 44.5 0.1 2.2 1 0 0 1 1 1 1 Cell-cell adhesion domain PTEN_C2 PF10409.9 EGG18072.1 - 1.2e-08 34.8 2.4 1.2e-08 34.8 2.4 2.5 2 1 1 3 3 3 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 EGG18072.1 - 2.5e-06 27.4 0.0 2.5e-06 27.4 0.0 3.2 4 1 0 4 4 4 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EGG18072.1 - 0.0011 18.7 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 EGG18072.1 - 0.0016 18.6 0.0 0.0016 18.6 0.0 2.7 3 0 0 3 3 3 1 Inositol hexakisphosphate CMV_1a PF12467.8 EGG18072.1 - 0.014 15.7 5.7 0.029 14.7 5.7 1.5 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF3430 PF11912.8 EGG18073.1 - 2.6e-10 40.7 16.4 3.2e-10 40.4 16.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGG18073.1 - 0.019 15.1 9.5 0.44 10.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3586) TIG PF01833.24 EGG18076.1 - 0.01 15.9 1.2 0.01 15.9 1.2 5.1 5 0 0 5 5 5 0 IPT/TIG domain EGF_2 PF07974.13 EGG18076.1 - 0.03 14.7 13.1 0.057 13.8 13.1 1.5 1 0 0 1 1 1 0 EGF-like domain DUF3244 PF11589.8 EGG18076.1 - 0.14 12.3 9.1 0.14 12.2 5.5 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) MACPF PF01823.19 EGG18077.1 - 9.3e-24 84.7 0.7 9.3e-24 84.7 0.7 2.1 1 1 1 2 2 2 1 MAC/Perforin domain Nod1 PF17114.5 EGG18078.1 - 0.007 16.5 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Gef2-related medial cortical node protein Nod1 FAO_M PF16350.5 EGG18078.1 - 0.077 13.3 0.0 0.79 10.1 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase central domain MACPF PF01823.19 EGG18079.1 - 1.3e-17 64.6 2.7 3.8e-17 63.1 2.7 1.8 1 0 0 1 1 1 1 MAC/Perforin domain PA14 PF07691.12 EGG18079.1 - 4.1e-05 23.4 0.0 9.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 PA14 domain DNase_II PF03265.15 EGG18080.1 - 2.6e-10 40.1 7.1 0.00023 20.6 0.1 3.7 3 1 0 3 3 3 2 Deoxyribonuclease II Dicty_REP PF05086.12 EGG18080.1 - 0.03 12.3 14.8 0.041 11.9 14.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4746 PF15928.5 EGG18080.1 - 0.18 11.2 1.4 0.34 10.3 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF3439 PF11921.8 EGG18080.1 - 0.61 10.1 11.7 1.2 9.1 11.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGG18080.1 - 1.2 9.1 21.7 2.4 8.2 21.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Tir_receptor_C PF07489.11 EGG18080.1 - 2.2 8.2 16.4 3.8 7.4 16.4 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Amidohydro_1 PF01979.20 EGG18083.1 - 4e-67 227.0 0.0 5.3e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGG18083.1 - 1.2e-06 28.2 0.0 0.036 13.5 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family CH_2 PF06294.11 EGG18083.1 - 0.037 14.1 2.2 2.8 8.1 0.4 3.6 3 0 0 3 3 3 0 CH-like domain in sperm protein LIM PF00412.22 EGG18084.1 - 6.6e-12 45.5 4.1 1.2e-11 44.7 4.1 1.4 1 0 0 1 1 1 1 LIM domain FliC_SP PF12613.8 EGG18084.1 - 0.085 13.4 0.8 1.4 9.5 0.3 2.4 2 0 0 2 2 2 0 Flagellin structural protein Ribosomal_L22 PF00237.19 EGG18085.1 - 1.5e-16 60.5 0.0 1.5e-16 60.5 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e DUF4337 PF14235.6 EGG18085.1 - 0.0023 18.1 7.2 0.0023 18.1 7.2 3.5 2 2 1 3 3 3 1 Domain of unknown function (DUF4337) 5TM-5TMR_LYT PF07694.12 EGG18085.1 - 0.13 11.8 1.9 0.31 10.5 1.9 1.6 1 0 0 1 1 1 0 5TMR of 5TMR-LYT VIT1 PF01988.19 EGG18085.1 - 0.23 11.3 0.1 0.23 11.3 0.1 2.6 3 0 0 3 3 3 0 VIT family SANT_DAMP1_like PF16282.5 EGG18086.1 - 0.008 16.4 0.3 0.031 14.5 0.3 2.0 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Chalcone_2 PF16035.5 EGG18086.1 - 0.14 11.9 2.7 0.49 10.1 0.5 2.6 2 0 0 2 2 2 0 Chalcone isomerase like EFG_C PF00679.24 EGG18087.1 - 5.9e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 1 0 1 1 1 1 Elongation factor G C-terminus SAM_2 PF07647.17 EGG18088.1 - 2.4e-06 27.6 0.0 3.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGG18088.1 - 0.00027 21.3 0.0 0.00043 20.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FlbT PF07378.11 EGG18088.1 - 0.0066 16.5 0.2 0.0096 16.0 0.2 1.5 1 1 0 1 1 1 1 Flagellar protein FlbT SAM_Ste50p PF09235.10 EGG18088.1 - 0.013 15.7 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_PNT PF02198.16 EGG18088.1 - 0.023 14.7 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF3047 PF11249.8 EGG18088.1 - 0.028 13.8 0.6 0.034 13.6 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3047) SAM_PNT PF02198.16 EGG18089.1 - 1.6e-10 40.8 0.4 2.1e-10 40.4 0.4 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain DAP3 PF10236.9 EGG18090.1 - 1.9e-05 24.0 0.1 4.6e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EGG18090.1 - 0.095 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PrgU PF09627.10 EGG18091.1 - 0.004 17.1 0.5 0.004 17.1 0.5 2.5 2 1 0 2 2 2 1 PrgU-like protein Pox_A32 PF04665.12 EGG18093.1 - 7.5e-05 22.3 0.0 0.00042 19.9 0.0 1.9 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 EGG18093.1 - 0.0028 17.9 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG18093.1 - 0.0084 16.5 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EGG18093.1 - 0.0089 16.0 0.5 0.05 13.5 0.2 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_10 PF12846.7 EGG18093.1 - 0.013 14.5 0.2 0.083 11.8 0.0 1.9 1 1 0 2 2 2 0 AAA-like domain MobB PF03205.14 EGG18093.1 - 0.018 15.0 0.0 0.09 12.7 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 EGG18093.1 - 0.044 13.3 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 EGG18093.1 - 0.079 13.0 0.7 0.2 11.7 0.7 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 EGG18093.1 - 0.13 11.6 0.0 15 4.9 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family TFIIA PF03153.13 EGG18094.1 - 0.0024 17.9 29.4 0.0032 17.5 29.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit NAD_Gly3P_dh_N PF01210.23 EGG18094.1 - 0.038 14.0 0.0 0.038 14.0 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SOG2 PF10428.9 EGG18094.1 - 0.21 10.8 14.9 0.27 10.4 14.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2367 PF10164.9 EGG18094.1 - 0.8 10.2 3.0 2.2 8.8 3.0 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) FHIPEP PF00771.20 EGG18094.1 - 1.7 7.0 3.6 19 3.6 0.0 2.1 2 0 0 2 2 2 0 FHIPEP family DUF2981 PF11200.8 EGG18094.1 - 3.2 7.4 11.6 4.2 7.0 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Menin PF05053.13 EGG18094.1 - 4.3 5.6 14.5 5.2 5.3 14.5 1.1 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 EGG18094.1 - 5.5 5.6 21.1 8.6 5.0 21.1 1.2 1 0 0 1 1 1 0 Presenilin Presenilin PF01080.17 EGG18095.1 - 0.011 14.5 1.3 0.013 14.3 1.3 1.0 1 0 0 1 1 1 0 Presenilin AAR2 PF05282.11 EGG18095.1 - 0.38 10.1 4.7 0.42 10.0 4.7 1.0 1 0 0 1 1 1 0 AAR2 protein SPATA3 PF15662.5 EGG18095.1 - 0.38 11.4 9.4 0.46 11.1 9.4 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family ASD2 PF08687.11 EGG18095.1 - 0.51 9.9 1.2 0.53 9.8 1.2 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Med3 PF11593.8 EGG18095.1 - 6.9 5.8 16.2 8.4 5.5 16.2 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Alpha_GJ PF03229.13 EGG18095.1 - 7.2 7.2 12.5 12 6.4 12.5 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J MBOAT PF03062.19 EGG18096.1 - 4.8e-24 85.4 19.4 1e-23 84.3 19.4 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EGG18096.1 - 0.0009 19.5 8.4 0.0013 18.9 7.4 1.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Chordopox_A13L PF05961.11 EGG18096.1 - 0.0097 16.1 0.3 0.035 14.3 0.3 2.0 1 0 0 1 1 1 1 Chordopoxvirus A13L protein Apt1 PF10351.9 EGG18096.1 - 3.5 6.4 13.5 6.1 5.6 13.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIF_alpha PF05793.12 EGG18096.1 - 7.2 5.1 18.1 11 4.5 18.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Menin PF05053.13 EGG18096.1 - 8.8 4.5 8.9 13 4.0 8.9 1.2 1 0 0 1 1 1 0 Menin LIM PF00412.22 EGG18097.1 - 2.2e-31 107.8 35.3 2e-12 47.1 5.8 3.1 3 0 0 3 3 3 3 LIM domain DUF2256 PF10013.9 EGG18097.1 - 0.8 9.9 0.0 0.8 9.9 0.0 4.9 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF4730 PF15873.5 EGG18098.1 - 0.00024 21.3 0.2 0.0003 21.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4730) Asp PF00026.23 EGG18099.1 - 8.7e-113 376.9 2.2 1.2e-112 376.5 2.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG18099.1 - 1.2e-13 51.7 1.6 7.1e-12 45.9 1.6 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGG18099.1 - 6.2e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EGG18099.1 - 0.00019 22.0 0.0 0.089 13.5 0.0 3.9 3 1 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 EGG18099.1 - 0.082 13.5 0.0 0.46 11.1 0.0 2.3 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DNase_II PF03265.15 EGG18100.1 - 3.4e-37 128.5 1.9 3.7e-22 79.0 2.7 2.5 2 0 0 2 2 2 2 Deoxyribonuclease II TIG PF01833.24 EGG18100.1 - 2.8e-31 107.4 84.4 7.8e-08 32.3 3.5 12.1 10 1 1 11 11 11 7 IPT/TIG domain SdrD_B PF17210.3 EGG18100.1 - 2.8e-16 59.7 5.2 0.00011 22.4 1.3 4.4 4 0 0 4 4 4 3 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG18100.1 - 8.6e-05 22.7 0.7 0.032 14.5 0.1 3.9 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain MetallophosN PF16371.5 EGG18100.1 - 0.00011 22.4 2.9 0.0015 18.7 0.0 3.5 3 0 0 3 3 3 1 N terminal of Calcineurin-like phosphoesterase G_glu_transpept PF01019.21 EGG18100.1 - 0.097 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase TIG PF01833.24 EGG18101.1 - 1.7e-30 105.0 36.2 3.3e-09 36.7 0.3 9.1 9 0 0 9 9 9 6 IPT/TIG domain DNase_II PF03265.15 EGG18101.1 - 5.4e-22 78.5 4.5 4.3e-21 75.5 4.5 2.2 1 1 0 1 1 1 1 Deoxyribonuclease II SdrD_B PF17210.3 EGG18101.1 - 0.00014 22.0 0.3 0.0021 18.2 0.1 3.0 3 0 0 3 3 3 1 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG18101.1 - 0.032 14.5 0.1 0.2 12.0 0.0 2.5 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain DNase_II PF03265.15 EGG18102.1 - 6.2e-32 111.2 0.2 3.5e-19 69.2 1.2 2.7 1 1 0 2 2 2 2 Deoxyribonuclease II TIG PF01833.24 EGG18102.1 - 1.5e-21 76.3 80.0 3.5e-07 30.2 2.8 11.6 11 1 0 11 11 11 6 IPT/TIG domain SdrD_B PF17210.3 EGG18102.1 - 7.6e-16 58.3 9.4 0.00012 22.2 0.4 5.4 6 0 0 6 6 6 3 SdrD B-like domain MetallophosN PF16371.5 EGG18102.1 - 6.2e-08 32.8 3.8 0.00098 19.3 0.0 4.6 4 0 0 4 4 4 2 N terminal of Calcineurin-like phosphoesterase CarboxypepD_reg PF13620.6 EGG18102.1 - 0.00015 22.0 3.0 0.043 14.1 0.1 4.1 4 0 0 4 4 4 2 Carboxypeptidase regulatory-like domain G_glu_transpept PF01019.21 EGG18102.1 - 0.19 10.5 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase TIG PF01833.24 EGG18103.1 - 7.3e-29 99.7 37.7 3.3e-07 30.3 2.9 9.7 8 1 1 9 9 9 6 IPT/TIG domain DNase_II PF03265.15 EGG18103.1 - 1.1e-20 74.2 2.9 9.7e-20 71.1 2.9 2.2 1 1 0 1 1 1 1 Deoxyribonuclease II SdrD_B PF17210.3 EGG18103.1 - 0.0017 18.6 0.1 0.029 14.6 0.0 2.9 2 0 0 2 2 2 1 SdrD B-like domain TIG PF01833.24 EGG18104.1 - 1.1e-27 95.9 74.3 3.5e-07 30.2 2.8 13.1 11 0 0 11 11 11 6 IPT/TIG domain DNase_II PF03265.15 EGG18104.1 - 2.9e-27 95.8 0.1 2.1e-12 47.0 0.0 3.2 2 1 0 2 2 2 2 Deoxyribonuclease II SdrD_B PF17210.3 EGG18104.1 - 1.8e-15 57.1 10.7 7.3e-05 23.0 0.8 5.1 5 0 0 5 5 5 3 SdrD B-like domain MetallophosN PF16371.5 EGG18104.1 - 3.4e-06 27.2 4.8 0.0031 17.8 0.0 4.0 4 0 0 4 4 4 2 N terminal of Calcineurin-like phosphoesterase CarboxypepD_reg PF13620.6 EGG18104.1 - 0.0018 18.5 0.2 0.0018 18.5 0.2 5.3 6 0 0 6 6 6 1 Carboxypeptidase regulatory-like domain G_glu_transpept PF01019.21 EGG18104.1 - 0.11 11.3 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Neocarzinostat PF00960.18 EGG18104.1 - 3.1 7.8 11.0 11 6.1 0.1 4.7 4 1 0 4 4 4 0 Neocarzinostatin family DNase_II PF03265.15 EGG18105.1 - 1.8e-20 73.5 6.7 3.4e-20 72.6 3.5 2.4 2 1 0 2 2 2 1 Deoxyribonuclease II gp37_C PF12604.8 EGG18105.1 - 0.035 13.8 0.1 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Tail fibre protein gp37 C terminal TIG PF01833.24 EGG18106.1 - 5e-30 103.4 34.5 5.9e-08 32.7 2.6 8.8 8 0 0 8 8 8 7 IPT/TIG domain SdrD_B PF17210.3 EGG18106.1 - 0.00026 21.2 0.1 0.004 17.4 0.0 2.6 2 0 0 2 2 2 1 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG18106.1 - 0.027 14.7 0.3 0.33 11.2 0.0 2.7 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain ACOX PF01756.19 EGG18107.1 - 3.2e-21 75.7 0.1 6.1e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGG18107.1 - 4.4e-15 55.7 0.1 1.4e-14 54.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGG18107.1 - 0.00011 22.4 1.5 0.00096 19.4 0.1 2.9 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EGG18107.1 - 0.02 15.4 0.0 0.059 13.9 0.0 1.8 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal zf-C3HC4_2 PF13923.6 EGG18108.1 - 6.8e-07 29.0 11.3 6.8e-07 29.0 11.3 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG18108.1 - 1.1e-05 25.1 8.1 1.1e-05 25.1 8.1 4.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG18108.1 - 1.8e-05 24.9 11.2 1.8e-05 24.9 11.2 4.3 2 1 1 3 3 3 1 Ring finger domain zf-TRAF PF02176.18 EGG18108.1 - 3.5e-05 24.4 9.5 3.5e-05 24.4 9.5 3.8 3 1 1 4 4 4 2 TRAF-type zinc finger zf-C3HC4 PF00097.25 EGG18108.1 - 5.5e-05 23.0 11.0 5.5e-05 23.0 11.0 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EGG18108.1 - 0.00053 19.8 2.6 0.002 18.0 2.6 2.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 EGG18108.1 - 0.0073 16.3 7.9 0.0073 16.3 7.9 3.4 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGG18108.1 - 0.017 15.3 8.6 0.017 15.3 8.6 3.4 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING SelP_N PF04592.14 EGG18109.1 - 5.2 6.4 12.1 7.3 5.9 12.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ras PF00071.22 EGG18110.1 - 3.8e-20 72.1 0.0 6.4e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG18110.1 - 5.3e-11 42.8 1.5 7.1e-11 42.4 0.2 1.9 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG18110.1 - 2.5e-05 23.8 0.0 3.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EGG18110.1 - 0.0078 16.0 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation adh_short PF00106.25 EGG18112.1 - 1.6e-05 24.5 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase FAM199X PF15814.5 EGG18112.1 - 0.015 14.4 0.9 0.027 13.6 0.9 1.3 1 0 0 1 1 1 0 Protein family FAM199X ChitinaseA_N PF08329.10 EGG18112.1 - 0.08 12.6 1.2 0.18 11.5 0.2 2.2 2 0 0 2 2 2 0 Chitinase A, N-terminal domain DIL PF01843.19 EGG18113.1 - 1.6e-20 73.3 4.6 1.7e-20 73.2 1.4 2.9 2 0 0 2 2 2 1 DIL domain HMMR_N PF15905.5 EGG18113.1 - 0.00034 20.2 27.1 0.00034 20.2 27.1 7.9 1 1 6 7 7 7 5 Hyaluronan mediated motility receptor N-terminal Oxysterol_BP PF01237.18 EGG18114.1 - 1.5e-101 340.0 0.0 1.9e-101 339.6 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein C1_1 PF00130.22 EGG18115.1 - 0.22 11.4 1.8 0.43 10.5 1.8 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Mon1 PF03164.14 EGG18116.1 - 0.019 14.1 0.5 0.023 13.8 0.5 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 RST PF12174.8 EGG18116.1 - 0.076 12.9 0.7 0.17 11.8 0.1 1.9 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain RasGEF PF00617.19 EGG18119.1 - 3.3e-36 125.1 4.9 3.3e-36 125.1 4.9 2.7 2 1 0 2 2 2 1 RasGEF domain LRR_8 PF13855.6 EGG18119.1 - 6.5e-13 48.2 11.5 1.2e-06 28.1 0.8 3.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EGG18119.1 - 6e-10 39.2 5.3 7.4e-06 26.2 1.2 4.0 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGG18119.1 - 4.6e-06 26.2 1.9 1.3e-05 24.8 1.9 1.7 1 0 0 1 1 1 1 Leucine-rich repeat CUB PF00431.20 EGG18120.1 - 0.00037 20.8 0.0 0.00051 20.4 0.0 1.2 1 0 0 1 1 1 1 CUB domain zf-C2H2_6 PF13912.6 EGG18121.1 - 0.00068 19.6 3.2 0.0017 18.3 3.2 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-MIZ PF02891.20 EGG18121.1 - 0.0012 18.5 3.7 0.0036 17.0 3.7 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C2H2_4 PF13894.6 EGG18121.1 - 0.062 14.2 1.8 0.062 14.2 1.8 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger Ribosomal_S16 PF00886.19 EGG18121.1 - 0.16 12.0 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S16 DUF3043 PF11241.8 EGG18121.1 - 0.19 11.7 0.7 0.37 10.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) SDH_beta PF03315.15 EGG18121.1 - 7.8 6.9 9.9 0.98 9.8 0.2 2.5 3 0 0 3 3 3 0 Serine dehydratase beta chain NOD PF06816.13 EGG18122.1 - 0.13 11.9 0.2 0.38 10.4 0.1 1.9 2 0 0 2 2 2 0 NOTCH protein A_deaminase PF00962.22 EGG18123.1 - 7.3e-78 262.2 0.0 3.4e-66 223.8 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase pEK499_p136 PF18736.1 EGG18123.1 - 0.037 13.6 0.1 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 HEPN pEK499 p136 EGF_2 PF07974.13 EGG18124.1 - 0.00019 21.7 12.3 0.00049 20.4 12.3 1.7 1 0 0 1 1 1 1 EGF-like domain Shisa PF13908.6 EGG18124.1 - 0.0049 17.1 0.7 0.012 15.8 0.7 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TIG PF01833.24 EGG18124.1 - 0.011 15.8 2.4 0.011 15.8 2.4 5.6 6 0 0 6 6 6 0 IPT/TIG domain Podoplanin PF05808.11 EGG18124.1 - 0.042 14.0 0.1 0.042 14.0 0.1 1.8 2 0 0 2 2 2 0 Podoplanin LRR_4 PF12799.7 EGG18124.1 - 0.048 14.1 18.6 6.4 7.3 6.5 5.1 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG18124.1 - 6.1 6.7 23.5 3.3 7.5 7.8 5.1 5 2 1 6 6 6 0 Leucine rich repeat TIG PF01833.24 EGG18125.1 - 1.6e-05 24.9 3.3 1.6e-05 24.9 3.3 3.1 2 0 0 2 2 2 1 IPT/TIG domain EGF_2 PF07974.13 EGG18125.1 - 0.018 15.4 11.8 0.018 15.4 11.8 3.2 3 0 0 3 3 3 0 EGF-like domain DUF3081 PF11280.8 EGG18125.1 - 0.018 14.8 0.2 0.04 13.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) EGF PF00008.27 EGG18125.1 - 0.52 10.7 29.2 0.068 13.5 7.2 2.9 2 0 0 2 2 2 0 EGF-like domain DUF4367 PF14285.6 EGG18125.1 - 2.6 8.5 8.0 0.27 11.7 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) TIG PF01833.24 EGG18126.1 - 2.9e-06 27.3 3.7 2.9e-06 27.3 3.7 3.9 5 0 0 5 5 5 1 IPT/TIG domain BB_PF PF18063.1 EGG18128.1 - 1.5e-38 132.5 5.0 2e-32 112.5 0.9 2.1 1 1 1 2 2 2 2 Beta barrel Pore-forming domain BB_PF PF18063.1 EGG18129.1 - 1.2e-21 77.3 2.4 6.9e-10 38.9 1.5 2.7 2 1 0 2 2 2 2 Beta barrel Pore-forming domain ketoacyl-synt PF00109.26 EGG18130.1 - 2e-61 207.8 0.1 3.3e-61 207.1 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG18130.1 - 1.3e-47 162.8 0.0 1.9e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGG18130.1 - 4.2e-38 130.0 0.1 5.2e-37 126.5 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGG18130.1 - 9.9e-28 97.3 0.0 3.9e-27 95.3 0.0 2.0 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGG18130.1 - 8.3e-22 77.8 0.0 1.4e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGG18130.1 - 9.5e-17 61.5 0.4 5.7e-16 59.0 0.1 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGG18130.1 - 2.5e-10 41.5 0.0 2.5e-09 38.3 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGG18130.1 - 2.9e-09 37.0 0.0 1.3e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EGG18130.1 - 7.5e-08 32.6 0.0 2e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EGG18130.1 - 3.8e-06 26.7 0.0 1.1e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGG18130.1 - 0.00068 19.1 0.1 0.0026 17.2 0.1 1.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.25 EGG18130.1 - 0.0039 16.7 0.1 0.0097 15.4 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG18130.1 - 0.019 14.5 0.0 0.087 12.4 0.0 2.0 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase BofA PF07441.11 EGG18130.1 - 1.4 9.2 3.7 25 5.2 2.8 2.4 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA NeA_P2 PF12312.8 EGG18131.1 - 1.3 8.4 10.8 0.52 9.7 2.7 2.1 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein Rrn6 PF10214.9 EGG18131.1 - 2.7 6.3 12.1 3.9 5.8 12.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Presenilin PF01080.17 EGG18131.1 - 8.5 5.0 5.1 11 4.7 5.1 1.1 1 0 0 1 1 1 0 Presenilin AAR2 PF05282.11 EGG18133.1 - 2.9 7.2 6.8 1.8 7.9 1.2 2.1 2 0 0 2 2 2 0 AAR2 protein Snf7 PF03357.21 EGG18135.1 - 1.4 8.5 7.7 1.5 8.4 7.7 1.1 1 0 0 1 1 1 0 Snf7 Myc_N PF01056.18 EGG18135.1 - 2.4 8.0 4.8 2.6 7.9 4.8 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Pes-10 PF07149.11 EGG18135.1 - 5.1 6.0 8.2 5.4 6.0 8.2 1.0 1 0 0 1 1 1 0 Pes-10 BB_PF PF18063.1 EGG18136.1 - 1.2e-36 126.3 1.6 4.9e-36 124.3 1.6 1.7 1 1 0 1 1 1 1 Beta barrel Pore-forming domain BB_PF PF18063.1 EGG18137.1 - 9.8e-42 142.9 0.0 1.5e-41 142.3 0.0 1.3 1 1 0 1 1 1 1 Beta barrel Pore-forming domain DUF4217 PF13959.6 EGG18138.1 - 0.1 12.8 3.1 0.66 10.2 0.8 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4217) PBP1_TM PF14812.6 EGG18139.1 - 0.26 11.7 3.7 0.24 11.8 1.9 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.7 EGG18141.1 - 4.2e-22 78.5 9.2 9.5e-09 35.7 0.6 8.6 3 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18141.1 - 4.1e-16 59.1 4.7 7.1e-05 23.3 0.7 9.0 8 2 2 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18141.1 - 2.8e-13 48.7 5.5 0.5 11.1 0.1 11.6 12 1 1 13 13 13 2 Ankyrin repeat Ank_5 PF13857.6 EGG18141.1 - 1.2e-06 28.7 20.1 0.56 10.6 0.1 10.5 7 5 5 12 12 12 2 Ankyrin repeats (many copies) Ank PF00023.30 EGG18141.1 - 0.012 16.0 7.5 72 4.1 0.2 7.3 8 1 1 9 9 9 0 Ankyrin repeat Ank_2 PF12796.7 EGG18142.1 - 2.6e-13 50.3 7.9 0.0029 18.2 0.0 7.1 2 2 7 9 9 9 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18142.1 - 1.2e-12 48.1 6.5 0.018 15.6 0.0 9.2 8 2 1 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18142.1 - 7.9e-08 32.0 5.3 16 6.5 0.0 9.1 11 0 0 11 11 11 2 Ankyrin repeat Ank_5 PF13857.6 EGG18142.1 - 5.9e-06 26.5 0.2 1.2 9.6 0.0 6.4 5 1 1 6 6 6 1 Ankyrin repeats (many copies) ADH_zinc_N PF00107.26 EGG18142.1 - 0.16 12.0 0.0 5.2 7.1 0.1 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase F-box PF00646.33 EGG18142.1 - 0.85 9.6 4.6 3.9 7.5 4.6 2.1 1 1 0 1 1 1 0 F-box domain Myotub-related PF06602.14 EGG18143.1 - 4.3e-14 52.2 0.4 4.1e-06 26.0 0.1 2.6 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain DUF3439 PF11921.8 EGG18143.1 - 0.023 14.7 1.6 0.023 14.7 1.6 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3439) DUF2779 PF11074.8 EGG18146.1 - 0.016 15.7 2.7 0.28 11.7 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function(DUF2779) Orf78 PF06024.12 EGG18146.1 - 6.7 7.1 9.5 1.3 9.3 0.5 2.9 3 0 0 3 3 3 0 Orf78 (ac78) EGF_2 PF07974.13 EGG18148.1 - 0.00051 20.4 16.4 0.00051 20.4 16.4 2.1 2 0 0 2 2 2 1 EGF-like domain EB PF01683.18 EGG18148.1 - 0.0018 18.5 1.3 0.0056 16.9 1.3 1.8 1 0 0 1 1 1 1 EB module DUF3844 PF12955.7 EGG18148.1 - 0.0036 17.4 2.8 0.0036 17.4 2.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) hEGF PF12661.7 EGG18148.1 - 0.022 15.4 12.4 0.022 15.4 12.4 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 EGG18148.1 - 0.16 12.0 10.8 0.32 11.1 4.3 2.5 2 0 0 2 2 2 0 Tenascin EGF domain I-EGF_1 PF18372.1 EGG18148.1 - 0.19 11.8 13.2 0.034 14.2 8.8 2.0 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 EGG18148.1 - 0.8 10.1 15.8 0.098 13.0 11.0 2.0 2 0 0 2 2 2 0 EGF-like domain EGF_CA PF07645.15 EGG18148.1 - 3.4 8.0 15.8 0.42 10.9 10.7 2.1 2 0 0 2 2 2 0 Calcium-binding EGF domain Dynamin_N PF00350.23 EGG18151.1 - 6.4e-38 130.5 0.0 6.4e-38 130.5 0.0 2.5 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EGG18151.1 - 4.9e-05 23.4 0.0 0.00027 21.0 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase TFIIA PF03153.13 EGG18151.1 - 0.021 14.9 15.0 0.034 14.1 15.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATP-synt_E PF05680.12 EGG18151.1 - 0.89 9.9 6.9 5.3 7.5 2.3 2.8 2 0 0 2 2 2 0 ATP synthase E chain ZZ PF00569.17 EGG18152.1 - 6.4e-11 41.9 6.7 1.1e-10 41.1 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 EGG18152.1 - 5e-08 33.0 0.1 9.7e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG18152.1 - 0.00021 21.5 0.0 0.00053 20.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 EGG18152.1 - 0.0022 18.2 7.7 0.005 17.1 7.7 1.6 1 0 0 1 1 1 1 C1 domain DUF2039 PF10217.9 EGG18152.1 - 0.085 13.2 4.6 0.27 11.6 4.6 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zinc-ribbons_6 PF07191.12 EGG18152.1 - 0.19 11.7 5.1 0.38 10.8 5.1 1.5 1 0 0 1 1 1 0 zinc-ribbons CH PF00307.31 EGG18153.1 - 5.4e-16 58.7 0.2 1e-15 57.9 0.2 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 EGG18153.1 - 0.0073 16.4 0.1 0.018 15.2 0.1 1.7 1 0 0 1 1 1 1 CH-like domain in sperm protein DUF1725 PF08333.11 EGG18153.1 - 0.14 11.8 1.6 0.2 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) tRNA-Thr_ED PF08915.11 EGG18156.1 - 0.0083 16.2 0.3 0.025 14.7 0.3 1.8 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase SmAKAP PF15127.6 EGG18156.1 - 0.75 11.0 4.6 0.94 10.7 0.4 2.5 2 0 0 2 2 2 0 Small membrane A-kinase anchor protein ASXH PF13919.6 EGG18157.1 - 1.7e-08 34.6 0.8 1.7e-08 34.6 0.8 6.1 5 2 1 6 6 6 2 Asx homology domain Med6 PF04934.14 EGG18158.1 - 9.9e-44 148.4 0.8 9.9e-44 148.4 0.8 1.8 2 0 0 2 2 2 1 MED6 mediator sub complex component SUIM_assoc PF16619.5 EGG18158.1 - 0.00059 19.8 5.5 0.0011 18.9 5.5 1.6 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 eIF-3_zeta PF05091.12 EGG18158.1 - 0.0025 16.9 1.0 0.0037 16.3 1.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PSY3 PF16836.5 EGG18158.1 - 0.048 13.2 1.3 0.13 11.8 0.7 1.9 1 1 1 2 2 2 0 Shu complex component Psy3, DNA-binding description RPN6_C_helix PF18503.1 EGG18158.1 - 0.15 11.8 0.1 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain TFIIA PF03153.13 EGG18158.1 - 0.28 11.1 11.5 0.32 10.9 11.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Erf4 PF10256.9 EGG18160.1 - 0.0007 19.7 3.8 0.13 12.4 0.3 2.6 1 1 1 2 2 2 2 Golgin subfamily A member 7/ERF4 family DUF4793 PF16041.5 EGG18160.1 - 0.021 15.0 1.3 0.021 15.0 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4793) Sulfate_transp PF00916.20 EGG18160.1 - 0.028 13.2 2.5 0.035 12.9 2.5 1.1 1 0 0 1 1 1 0 Sulfate permease family Glucos_trans_II PF14264.6 EGG18160.1 - 0.048 13.0 4.8 0.06 12.7 4.8 1.2 1 0 0 1 1 1 0 Glucosyl transferase GtrII ER_lumen_recept PF00810.18 EGG18160.1 - 0.074 13.9 2.0 0.11 13.4 2.0 1.2 1 0 0 1 1 1 0 ER lumen protein retaining receptor Flp1_like PF16982.5 EGG18160.1 - 8.4 5.9 12.1 33 4.0 12.1 2.1 1 1 0 1 1 1 0 Putative Flagellin, Flp1-like, domain CBM49 PF09478.10 EGG18162.1 - 3.3e-13 49.7 0.2 4.5e-13 49.3 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Methyltransf_2 PF00891.18 EGG18163.1 - 2.1e-21 76.2 0.0 4.8e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGG18163.1 - 0.018 15.0 0.2 0.046 13.7 0.2 1.7 1 0 0 1 1 1 0 Dimerisation domain Coilin_N PF15862.5 EGG18163.1 - 1.1 9.1 0.0 1.1 9.1 0.0 11.0 4 2 4 9 9 9 0 Coilin N-terminus BcrAD_BadFG PF01869.20 EGG18164.1 - 3.5e-41 141.5 0.2 4e-41 141.3 0.2 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 EGG18164.1 - 1.5e-05 24.7 0.1 0.00017 21.1 0.0 2.1 2 0 0 2 2 2 1 ROK family DUF5643 PF18705.1 EGG18164.1 - 0.016 15.2 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5643) FGGY_N PF00370.21 EGG18164.1 - 0.044 13.3 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Hydant_A_N PF05378.13 EGG18164.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region EGF_2 PF07974.13 EGG18166.1 - 0.0023 18.2 5.8 0.0048 17.2 5.8 1.5 1 0 0 1 1 1 1 EGF-like domain AbrB_C PF18277.1 EGG18166.1 - 0.061 13.0 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 AbrB C-terminal domain fn3 PF00041.21 EGG18167.1 - 0.00068 19.9 8.2 0.22 11.9 0.1 4.3 3 1 1 4 4 4 2 Fibronectin type III domain SKG6 PF08693.10 EGG18167.1 - 0.01 15.2 5.0 0.02 14.3 5.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Tissue_fac PF01108.17 EGG18167.1 - 0.045 13.6 0.2 0.12 12.2 0.2 1.7 1 0 0 1 1 1 0 Tissue factor Collectrin PF16959.5 EGG18167.1 - 0.048 13.4 1.1 0.75 9.6 0.2 2.7 2 0 0 2 2 2 0 Renal amino acid transporter EGF_2 PF07974.13 EGG18168.1 - 0.004 17.5 7.2 0.011 16.1 7.2 1.8 1 0 0 1 1 1 1 EGF-like domain SKG6 PF08693.10 EGG18168.1 - 0.014 14.8 0.4 0.03 13.8 0.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RHIM PF12721.7 EGG18168.1 - 5.5 7.6 6.8 5.3 7.6 0.0 3.1 3 0 0 3 3 3 0 RIP homotypic interaction motif EGF_2 PF07974.13 EGG18169.1 - 0.01 16.2 7.2 0.03 14.7 7.2 1.8 1 0 0 1 1 1 0 EGF-like domain fn3 PF00041.21 EGG18169.1 - 1.1 9.7 10.9 7.8 6.9 0.0 5.0 4 1 1 5 5 5 0 Fibronectin type III domain EGF_2 PF07974.13 EGG18171.1 - 2.9e-05 24.3 24.1 0.0043 17.4 7.2 2.9 2 0 0 2 2 2 2 EGF-like domain fn3 PF00041.21 EGG18171.1 - 0.00067 20.0 22.5 0.11 12.9 0.1 7.2 8 0 0 8 8 8 2 Fibronectin type III domain Tissue_fac PF01108.17 EGG18171.1 - 0.0039 17.0 5.5 2.9 7.8 0.0 4.5 4 0 0 4 4 4 2 Tissue factor Collectrin PF16959.5 EGG18171.1 - 0.065 13.0 0.2 19 5.0 0.0 3.2 3 0 0 3 3 3 0 Renal amino acid transporter Tmemb_18A PF09771.9 EGG18171.1 - 0.31 11.4 1.1 1.1 9.7 1.1 1.8 1 0 0 1 1 1 0 Transmembrane protein 188 LRR_4 PF12799.7 EGG18172.1 - 0.00035 20.9 11.7 0.085 13.3 0.6 5.7 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG18172.1 - 0.03 14.1 1.8 25 4.8 0.3 4.3 4 1 1 5 5 5 0 Leucine rich repeat Peptidase_M6 PF05547.11 EGG18172.1 - 0.033 12.5 0.0 0.054 11.8 0.0 1.2 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 EGF_2 PF07974.13 EGG18173.1 - 0.00016 22.0 9.9 0.0005 20.4 9.9 1.9 1 0 0 1 1 1 1 EGF-like domain DUF3972 PF13118.6 EGG18174.1 - 1.5e-06 28.6 1.6 1.7e-06 28.4 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3972) CCDC144C PF14915.6 EGG18174.1 - 0.0014 17.8 1.5 0.0015 17.7 1.5 1.0 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region FliD_N PF02465.18 EGG18174.1 - 0.0033 18.1 1.6 0.0036 18.0 1.6 1.0 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus DUF496 PF04363.12 EGG18174.1 - 0.032 14.3 0.2 0.034 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF496) DUF2570 PF10828.8 EGG18174.1 - 0.035 13.9 7.3 0.04 13.7 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Hemerythrin PF01814.23 EGG18174.1 - 0.042 14.5 1.2 0.046 14.3 1.2 1.0 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Retrotrans_gag PF03732.17 EGG18174.1 - 0.082 13.2 1.7 0.085 13.1 1.7 1.0 1 0 0 1 1 1 0 Retrotransposon gag protein Med9 PF07544.13 EGG18174.1 - 0.29 11.3 7.2 3.7 7.7 1.7 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF485 PF04341.12 EGG18176.1 - 0.079 12.9 0.1 0.27 11.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Tissue_fac PF01108.17 EGG18176.1 - 0.1 12.5 1.6 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 Tissue factor EGF_2 PF07974.13 EGG18176.1 - 0.27 11.6 5.6 0.52 10.7 5.6 1.4 1 0 0 1 1 1 0 EGF-like domain Collectrin PF16959.5 EGG18176.1 - 0.5 10.1 3.2 2.7 7.7 3.3 2.4 1 1 0 1 1 1 0 Renal amino acid transporter Tissue_fac PF01108.17 EGG18177.1 - 7.8 6.4 8.3 0.3 10.9 0.2 2.9 3 0 0 3 3 3 0 Tissue factor PIH1 PF08190.12 EGG18178.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 PIH1 N-terminal domain TAN PF11640.8 EGG18179.1 - 0.02 15.0 0.2 0.02 15.0 0.2 2.3 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Vma12 PF11712.8 EGG18179.1 - 0.029 14.4 0.1 0.14 12.2 0.1 2.2 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Peptidase_S10 PF00450.22 EGG18180.1 - 9.2e-06 25.3 0.0 1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 EGG18181.1 - 9e-20 71.5 0.0 9.9e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase SpoIIIAH PF12685.7 EGG18185.1 - 0.035 13.9 4.5 0.042 13.7 4.5 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2149 PF09919.9 EGG18185.1 - 0.095 13.0 0.7 0.16 12.2 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) RIFIN PF02009.16 EGG18185.1 - 0.1 12.5 3.1 0.12 12.2 3.1 1.1 1 0 0 1 1 1 0 Rifin RIFIN PF02009.16 EGG18187.1 - 0.065 13.1 7.2 0.074 12.9 7.2 1.1 1 0 0 1 1 1 0 Rifin SpoIIIAH PF12685.7 EGG18187.1 - 0.089 12.6 7.0 0.11 12.3 7.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Rootletin PF15035.6 EGG18188.1 - 0.063 13.3 1.7 0.071 13.1 1.7 1.0 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4254 PF14063.6 EGG18188.1 - 0.07 12.9 0.1 0.15 11.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) USP7_ICP0_bdg PF12436.8 EGG18189.1 - 7.7e-62 208.7 0.3 2.2e-61 207.2 0.3 1.8 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EGG18189.1 - 2e-55 187.7 4.5 3.6e-54 183.6 0.4 3.3 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EGG18189.1 - 8.7e-54 182.7 1.9 8.7e-54 182.7 1.9 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG18189.1 - 2e-18 67.1 0.1 2e-18 67.1 0.1 4.0 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EGG18189.1 - 2.6e-12 46.9 0.6 2.6e-12 46.9 0.6 2.9 3 0 0 3 3 3 1 MATH domain Ubiquitin_2 PF14560.6 EGG18189.1 - 1.4e-05 25.4 0.0 0.00014 22.2 0.0 2.8 3 0 0 3 3 3 1 Ubiquitin-like domain ubiquitin PF00240.23 EGG18189.1 - 0.0029 17.3 3.7 0.56 10.0 0.0 4.3 5 0 0 5 5 5 1 Ubiquitin family Endonuc_subdom PF09062.10 EGG18189.1 - 1.1 10.1 4.8 7.3 7.5 0.2 2.9 2 0 0 2 2 2 0 PI-PfuI Endonuclease subdomain RasGEF PF00617.19 EGG18190.1 - 2.1e-59 200.7 1.1 3.4e-59 200.0 0.2 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGG18190.1 - 3.3e-24 85.1 1.3 3.3e-24 85.1 1.3 3.8 4 0 0 4 4 4 1 RasGEF N-terminal motif DEP PF00610.21 EGG18192.1 - 8.5e-39 131.5 0.6 2.2e-19 69.2 0.0 2.4 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF603 PF04645.12 EGG18192.1 - 0.0028 17.4 0.4 0.0062 16.3 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF603 Lung_7-TM_R PF06814.13 EGG18193.1 - 2.5e-11 43.4 13.1 2.5e-11 43.4 13.1 4.3 3 1 0 3 3 3 1 Lung seven transmembrane receptor DUF4587 PF15248.6 EGG18193.1 - 0.083 13.7 5.1 0.27 12.1 5.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) LapA_dom PF06305.11 EGG18193.1 - 3.3 7.6 19.8 0.56 10.1 0.1 5.1 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain LNS2 PF08235.13 EGG18194.1 - 6.6e-52 176.2 0.2 1.4e-51 175.2 0.2 1.5 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EGG18194.1 - 1.1e-38 131.3 0.0 3.1e-38 129.9 0.0 1.8 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 EGG18194.1 - 3.6e-23 81.6 0.1 1e-22 80.2 0.1 1.9 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain DUF948 PF06103.11 EGG18194.1 - 0.042 14.1 0.1 0.042 14.1 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) LNS2 PF08235.13 EGG18195.1 - 8.7e-44 149.7 0.1 1.3e-43 149.1 0.1 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Catalase_C PF18011.1 EGG18195.1 - 0.11 12.2 0.1 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 C-terminal domain found in long catalases DUF3439 PF11921.8 EGG18195.1 - 0.35 10.9 8.6 0.59 10.1 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Chordopox_A33R PF05966.12 EGG18196.1 - 0.014 14.7 0.5 0.015 14.5 0.5 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Pkinase PF00069.25 EGG18197.1 - 1.5e-65 221.2 0.2 2.9e-65 220.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG18197.1 - 1e-45 156.1 0.0 2e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG18197.1 - 1.6e-05 23.9 1.3 0.00058 18.7 0.0 2.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGG18197.1 - 0.00033 20.6 0.0 0.00097 19.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG18197.1 - 0.0079 15.5 0.0 0.02 14.2 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG18197.1 - 0.043 13.2 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Utp14 PF04615.13 EGG18197.1 - 0.55 8.7 21.3 1 7.9 21.3 1.3 1 0 0 1 1 1 0 Utp14 protein Med13_C PF06333.12 EGG18197.1 - 4.5 6.5 15.5 9.8 5.3 15.5 1.5 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain zf-RING_14 PF17978.1 EGG18198.1 - 0.0034 17.8 4.2 0.0062 16.9 4.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain NARP1 PF12569.8 EGG18198.1 - 0.045 12.6 9.0 0.066 12.1 9.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cys_rich_CWC PF14375.6 EGG18198.1 - 0.081 13.3 4.2 0.22 12.0 4.2 2.0 1 1 0 1 1 1 0 Cysteine-rich CWC POX PF07526.11 EGG18198.1 - 1 9.9 11.1 7.3 7.2 7.6 2.1 2 0 0 2 2 2 0 Associated with HOX P5-ATPase PF12409.8 EGG18198.1 - 1.6 8.8 6.5 6.1 7.0 0.1 2.1 2 0 0 2 2 2 0 P5-type ATPase cation transporter Presenilin PF01080.17 EGG18198.1 - 1.9 7.1 9.4 2.4 6.8 9.4 1.1 1 0 0 1 1 1 0 Presenilin Secretin_N_2 PF07655.13 EGG18198.1 - 3.7 8.1 20.0 0.43 11.1 6.5 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain FYDLN_acid PF09538.10 EGG18198.1 - 3.7 8.3 11.0 2.4 8.9 8.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Peroxin-13_N PF04088.13 EGG18198.1 - 7.5 6.8 7.3 9.2 6.5 4.8 1.9 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Methyltransf_11 PF08241.12 EGG18200.1 - 2.2e-16 60.3 0.0 3.8e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG18200.1 - 9.9e-14 51.8 0.0 1.9e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG18200.1 - 1.1e-08 35.0 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG18200.1 - 7.9e-07 29.8 0.0 1.5e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG18200.1 - 0.00022 21.1 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG18200.1 - 0.0016 17.9 0.0 0.0029 17.0 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EGG18200.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase DREV PF05219.12 EGG18200.1 - 0.036 13.2 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_15 PF09445.10 EGG18200.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase S_tail_recep_bd PF14928.6 EGG18200.1 - 0.076 13.6 0.1 0.13 12.9 0.1 1.4 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain MTS PF05175.14 EGG18200.1 - 0.09 12.3 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EGG18200.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase RRM_1 PF00076.22 EGG18201.1 - 8.2e-12 44.8 0.5 6.8e-07 29.0 0.1 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3439 PF11921.8 EGG18201.1 - 0.2 11.6 1.6 0.42 10.6 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4175 PF13779.6 EGG18201.1 - 0.24 9.3 6.2 0.43 8.4 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CSG2 PF16965.5 EGG18201.1 - 0.99 8.3 2.9 1.8 7.4 2.9 1.5 1 0 0 1 1 1 0 Ceramide synthase regulator RRM_1 PF00076.22 EGG18202.1 - 1e-20 73.3 0.0 1.4e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG18202.1 - 3.1e-05 23.7 0.0 6.2e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EGG18202.1 - 0.0014 18.3 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 EGG18202.1 - 0.0021 18.0 0.1 0.003 17.5 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EGG18202.1 - 0.012 15.8 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 EGG18202.1 - 0.029 14.4 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF948 PF06103.11 EGG18203.1 - 0.01 16.1 3.7 0.01 16.1 3.7 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 EGG18203.1 - 0.081 13.1 20.0 0.025 14.8 9.6 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 EGG18203.1 - 0.19 11.3 14.2 0.28 10.7 14.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_lysozyme2 PF18013.1 EGG18203.1 - 0.32 11.0 5.1 0.15 12.1 2.5 1.7 1 1 1 2 2 2 0 Phage tail lysozyme Tweety PF04906.13 EGG18203.1 - 1.6 7.3 4.8 0.45 9.1 0.6 1.9 1 1 1 2 2 2 0 Tweety ApoO PF09769.9 EGG18203.1 - 2.7 8.0 8.4 2.9 7.9 1.1 2.8 1 1 2 3 3 3 0 Apolipoprotein O Occludin_ELL PF07303.13 EGG18203.1 - 3 8.6 23.1 16 6.3 5.8 3.2 1 1 2 3 3 3 0 Occludin homology domain Golgin_A5 PF09787.9 EGG18203.1 - 3.2 7.1 26.6 0.41 10.1 14.7 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 STAT_alpha PF01017.20 EGG18203.1 - 3.8 7.4 22.1 1.7 8.5 10.2 2.1 1 1 1 2 2 2 0 STAT protein, all-alpha domain Lebercilin PF15619.6 EGG18203.1 - 7 6.3 32.3 6 6.5 7.7 2.8 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease KxDL PF10241.9 EGG18203.1 - 7.1 7.0 17.7 0.5 10.7 4.6 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein UPF0231 PF06062.11 EGG18203.1 - 7.5 6.9 14.1 4.8 7.5 2.5 2.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0231) Lectin_N PF03954.14 EGG18203.1 - 8.5 6.1 12.1 17 5.1 9.9 2.6 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 EGG18203.1 - 9.7 6.3 13.5 12 6.0 4.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) P2X_receptor PF00864.19 EGG18204.1 - 5.9e-27 94.7 0.1 6.1e-14 51.9 0.3 2.6 1 1 1 2 2 2 2 ATP P2X receptor XRN_N PF03159.18 EGG18205.1 - 6.8e-73 245.1 0.1 2.1e-72 243.4 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EGG18205.1 - 5.7e-58 196.9 11.1 1.8e-42 145.9 2.6 2.8 3 1 1 4 4 4 2 Xrn1 helical domain RRM_1 PF00076.22 EGG18205.1 - 1.3e-20 72.9 0.8 1.4e-09 37.6 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAP_C PF03943.13 EGG18205.1 - 0.037 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 TAP C-terminal domain zf-CCHC_3 PF13917.6 EGG18205.1 - 0.31 11.1 1.0 0.81 9.7 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle BRCT_2 PF16589.5 EGG18206.1 - 0.0002 21.7 0.1 0.00058 20.2 0.1 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain WWE PF02825.20 EGG18206.1 - 0.00025 21.6 0.5 0.0007 20.1 0.5 1.9 1 0 0 1 1 1 1 WWE domain MGC-24 PF05283.11 EGG18206.1 - 2 8.8 7.4 4.2 7.8 7.4 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Tmemb_14 PF03647.13 EGG18207.1 - 5e-24 84.9 13.9 6.1e-24 84.6 13.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C TssN PF17555.2 EGG18207.1 - 1.1 8.6 6.9 0.3 10.4 4.0 1.5 1 1 0 1 1 1 0 Type VI secretion system, TssN BTB_2 PF02214.22 EGG18208.1 - 1.8e-13 50.7 0.5 4.2e-13 49.5 0.5 1.6 1 0 0 1 1 1 1 BTB/POZ domain Exo_endo_phos PF03372.23 EGG18208.1 - 0.0022 17.5 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_60s PF00428.19 EGG18209.1 - 8.4e-22 77.6 13.1 9.7e-22 77.4 13.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF677 PF05055.12 EGG18209.1 - 0.65 8.8 7.6 0.93 8.3 7.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF677) AIM24 PF01987.17 EGG18210.1 - 5.5e-56 189.6 1.2 7.3e-56 189.2 1.2 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 VASt PF16016.5 EGG18212.1 - 1.3e-26 93.9 1.7 1.3e-26 93.9 1.7 1.9 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EGG18212.1 - 2.9e-18 65.8 0.1 8.1e-18 64.4 0.1 1.8 1 0 0 1 1 1 1 GRAM domain T2SSM PF04612.12 EGG18212.1 - 0.24 11.4 0.0 0.24 11.4 0.0 3.2 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein M DUF4746 PF15928.5 EGG18212.1 - 7.4 5.9 13.0 14 5.0 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ras PF00071.22 EGG18213.1 - 1.1e-60 204.0 0.3 1.2e-60 203.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG18213.1 - 5.4e-33 113.8 0.1 8.4e-33 113.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG18213.1 - 1.5e-13 50.6 0.0 1.9e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG18213.1 - 0.00026 20.4 0.0 0.00033 20.1 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EGG18213.1 - 0.00048 20.0 0.0 0.00064 19.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EGG18213.1 - 0.00057 20.0 0.0 0.00092 19.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG18213.1 - 0.00058 19.4 0.0 0.0011 18.6 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGG18213.1 - 0.0011 18.9 0.1 0.52 10.2 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase Arm PF00514.23 EGG18215.1 - 0.0058 16.6 0.0 2.9 8.1 0.0 2.9 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat zf-C3HC4 PF00097.25 EGG18216.1 - 2e-07 30.8 8.3 4.8e-07 29.5 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG18216.1 - 3.2e-07 30.1 9.9 5.6e-07 29.3 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG18216.1 - 3.4e-07 30.5 10.0 6.4e-07 29.6 10.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGG18216.1 - 2.7e-06 27.1 4.5 4.6e-06 26.4 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PWI PF01480.17 EGG18216.1 - 3.4e-06 27.3 0.1 1.3e-05 25.5 0.1 2.0 1 0 0 1 1 1 1 PWI domain zf-rbx1 PF12678.7 EGG18216.1 - 9.4e-05 22.6 6.4 0.00028 21.1 6.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGG18216.1 - 0.0012 18.9 7.6 0.0028 17.7 7.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG18216.1 - 0.012 15.5 7.5 0.025 14.5 7.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_9 PF14369.6 EGG18216.1 - 0.031 14.5 1.3 0.031 14.5 1.3 2.3 2 0 0 2 2 2 0 zinc-ribbon zf-RING_6 PF14835.6 EGG18216.1 - 0.073 13.0 2.2 0.13 12.1 2.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EGG18216.1 - 0.29 11.2 6.8 0.71 10.0 6.8 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGG18216.1 - 0.66 9.8 5.4 1.8 8.4 5.4 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Striatin PF08232.12 EGG18216.1 - 0.84 10.2 16.6 3.5 8.2 5.9 3.3 3 0 0 3 3 3 0 Striatin family Connexin PF00029.19 EGG18216.1 - 1.6 8.4 6.3 0.41 10.4 1.7 2.2 2 0 0 2 2 2 0 Connexin zf-C3HC4_4 PF15227.6 EGG18216.1 - 4.6 7.5 10.2 9.3 6.5 10.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pep1_7 PF17232.2 EGG18217.1 - 0.057 13.9 0.6 0.078 13.4 0.6 1.2 1 0 0 1 1 1 0 Elicitor peptide 1-7 G-alpha PF00503.20 EGG18218.1 - 7.5e-120 400.3 0.8 9.3e-120 400.0 0.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGG18218.1 - 1.5e-15 57.1 0.4 1e-11 44.6 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG18218.1 - 0.00057 19.3 0.2 0.3 10.4 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGG18218.1 - 0.0045 17.2 0.2 2.6 8.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase THDPS_N PF14790.6 EGG18218.1 - 0.062 13.1 0.1 0.19 11.5 0.1 1.8 1 1 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Ras PF00071.22 EGG18219.1 - 1.7e-52 177.3 0.0 1.1e-51 174.6 0.0 2.1 2 0 0 2 2 2 1 Ras family BTB PF00651.31 EGG18219.1 - 4.3e-36 123.5 0.5 6.1e-19 68.3 0.0 3.3 2 1 0 2 2 2 2 BTB/POZ domain Roc PF08477.13 EGG18219.1 - 1.3e-20 73.8 0.0 2.9e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG18219.1 - 4.6e-08 32.7 0.0 1.6e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family BACK PF07707.15 EGG18219.1 - 3.3e-05 23.9 0.0 0.0012 18.9 0.0 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch GTP_EFTU PF00009.27 EGG18219.1 - 0.031 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain BTB_3 PF16017.5 EGG18219.1 - 0.055 13.6 0.3 0.62 10.2 0.0 2.7 2 2 1 3 3 3 0 BTB/POZ domain U6-snRNA_bdg PF10596.9 EGG18219.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 U6-snRNA interacting domain of PrP8 LRR_4 PF12799.7 EGG18220.1 - 7.6e-35 118.4 40.8 8.2e-10 38.8 0.6 7.8 3 1 4 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG18220.1 - 8.6e-25 86.3 26.7 4.1e-11 42.5 2.1 5.0 1 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 EGG18220.1 - 2e-22 79.5 25.3 1.9e-08 34.0 1.7 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 EGG18220.1 - 9.9e-08 31.5 18.1 0.08 13.0 0.2 8.1 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 EGG18220.1 - 0.013 16.0 27.4 8.1 7.4 0.2 9.5 11 2 0 11 11 11 0 Leucine Rich Repeat Ribosomal_L6e PF01159.19 EGG18220.1 - 0.064 13.8 3.6 0.36 11.4 1.4 2.4 2 0 0 2 2 2 0 Ribosomal protein L6e FAM176 PF14851.6 EGG18220.1 - 2.1 8.0 8.8 3.8 7.2 8.8 1.3 1 0 0 1 1 1 0 FAM176 family DIL PF01843.19 EGG18220.1 - 2.6 8.4 6.3 1.1 9.6 0.9 2.7 2 1 1 3 3 3 0 DIL domain Pox_Ag35 PF03286.14 EGG18220.1 - 3.1 7.6 15.0 6.2 6.6 15.0 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4611 PF15387.6 EGG18220.1 - 7.7 6.8 15.9 19 5.5 15.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) BB_PF PF18063.1 EGG18221.1 - 6.2e-29 101.1 0.1 9.8e-29 100.4 0.1 1.3 1 0 0 1 1 1 1 Beta barrel Pore-forming domain PAP_assoc PF03828.19 EGG18221.1 - 0.099 12.9 0.1 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 Cid1 family poly A polymerase Ank_2 PF12796.7 EGG18222.1 - 9.9e-15 54.9 4.5 0.0021 18.6 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EGG18222.1 - 7.2e-08 32.3 15.3 0.008 16.1 0.0 5.2 5 1 0 5 5 5 3 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EGG18222.1 - 4.9e-07 29.5 0.8 12 6.9 0.0 8.8 9 0 0 9 9 9 1 Ankyrin repeat Ank_4 PF13637.6 EGG18222.1 - 3.3e-05 24.3 4.0 13 6.5 0.0 6.4 5 2 1 6 6 6 1 Ankyrin repeats (many copies) p450 PF00067.22 EGG18223.1 - 6.3e-82 275.8 0.0 8e-82 275.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1771 PF08590.10 EGG18224.1 - 3.7e-15 56.0 7.1 3.7e-15 56.0 7.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) KH_1 PF00013.29 EGG18224.1 - 3.9e-13 49.0 0.0 7.2e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 KH domain Smr PF01713.21 EGG18224.1 - 1.8e-06 28.2 0.0 5.3e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Smr domain T5orf172 PF10544.9 EGG18224.1 - 0.0055 17.2 0.4 0.041 14.4 0.0 2.5 3 0 0 3 3 3 1 T5orf172 domain CemA PF03040.14 EGG18224.1 - 0.0068 16.4 1.1 0.011 15.7 1.1 1.3 1 0 0 1 1 1 1 CemA family DUF4407 PF14362.6 EGG18224.1 - 0.5 9.7 19.2 0.011 15.1 12.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RRF PF01765.19 EGG18224.1 - 2.6 8.0 16.0 0.35 10.8 4.1 2.2 2 0 0 2 2 2 0 Ribosome recycling factor NLRC4_HD2 PF17776.1 EGG18224.1 - 3.4 8.2 6.4 0.4 11.2 0.3 2.2 2 0 0 2 2 2 0 NLRC4 helical domain HD2 Pkinase PF00069.25 EGG18225.1 - 1.9e-44 152.0 0.2 1.6e-31 109.7 0.0 5.0 5 1 0 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG18225.1 - 6.5e-23 81.3 0.1 1.5e-10 40.8 0.0 4.0 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EGG18225.1 - 2.2e-16 60.2 0.1 2.2e-16 60.2 0.1 3.1 3 0 0 3 3 3 1 RWD domain tRNA-synt_His PF13393.6 EGG18225.1 - 2.7e-16 59.8 0.1 1.5e-14 54.0 0.0 3.2 2 1 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.7 EGG18225.1 - 1.7e-13 50.7 0.0 1.7e-13 50.7 0.0 6.2 5 1 0 5 5 5 1 Anticodon binding domain of tRNAs HGTP_anticodon PF03129.20 EGG18225.1 - 2.9e-09 37.0 0.2 1.3e-07 31.7 0.0 2.8 2 0 0 2 2 2 1 Anticodon binding domain APH PF01636.23 EGG18225.1 - 0.049 13.6 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Copine PF07002.16 EGG18226.1 - 2.8e-67 226.3 0.0 3.8e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGG18226.1 - 3.4e-19 69.0 0.0 2.1e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGG18226.1 - 8.8e-07 29.2 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EGG18226.1 - 0.023 15.0 0.1 0.041 14.1 0.1 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain SET PF00856.28 EGG18227.1 - 2.2e-07 31.4 1.6 1.7e-06 28.6 0.0 2.6 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EGG18227.1 - 7.9e-05 23.4 0.3 0.00016 22.4 0.3 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding DUF4484 PF14831.6 EGG18227.1 - 0.23 11.5 3.4 0.38 10.7 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) MID_MedPIWI PF18296.1 EGG18227.1 - 0.43 10.3 9.5 0.74 9.6 9.5 1.3 1 0 0 1 1 1 0 MID domain of medPIWI LMBR1 PF04791.16 EGG18227.1 - 0.69 8.8 6.9 0.22 10.4 4.5 1.4 2 0 0 2 2 2 0 LMBR1-like membrane protein RP-C_C PF11800.8 EGG18227.1 - 1.9 8.5 6.8 3.5 7.7 6.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Menin PF05053.13 EGG18227.1 - 2.8 6.2 11.8 4.2 5.6 11.8 1.2 1 0 0 1 1 1 0 Menin Engrail_1_C_sig PF10525.9 EGG18228.1 - 0.4 9.9 1.5 0.95 8.7 1.5 1.7 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain Abhydrolase_1 PF00561.20 EGG18229.1 - 1.7e-16 60.6 0.3 1.1e-15 58.0 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG18229.1 - 1.3e-13 50.8 0.0 2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG18229.1 - 1.9e-12 48.3 0.0 2.5e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 EGG18229.1 - 0.0016 17.5 0.1 0.0079 15.3 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) FSH1 PF03959.13 EGG18229.1 - 0.078 12.6 0.1 24 4.5 0.2 2.9 2 1 1 3 3 3 0 Serine hydrolase (FSH1) SPACA9 PF15120.6 EGG18229.1 - 0.11 12.2 0.3 0.19 11.5 0.3 1.2 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 Lipase_3 PF01764.25 EGG18229.1 - 0.12 12.2 0.1 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Membr_traf_MHD PF10540.9 EGG18230.1 - 0.0005 20.3 9.0 0.0022 18.2 0.7 3.9 2 1 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain ABC2_membrane PF01061.24 EGG18231.1 - 2.2e-88 295.2 57.2 5.6e-49 166.4 21.7 3.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EGG18231.1 - 1.2e-41 142.5 0.2 4.9e-22 78.9 0.0 3.4 4 0 0 4 4 2 2 ABC transporter AAA_22 PF13401.6 EGG18231.1 - 1.8e-07 31.5 2.9 0.016 15.5 0.6 3.8 3 2 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 EGG18231.1 - 2e-07 31.0 0.3 0.0018 18.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGG18231.1 - 4.2e-07 30.5 0.9 0.029 14.8 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.6 EGG18231.1 - 3.6e-06 26.7 0.0 0.0064 16.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGG18231.1 - 1.5e-05 25.3 0.1 0.073 13.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 EGG18231.1 - 1.9e-05 24.0 0.0 0.081 12.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 EGG18231.1 - 2.2e-05 24.7 3.3 0.17 12.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 EGG18231.1 - 6.2e-05 23.4 2.1 0.01 16.2 0.7 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGG18231.1 - 8.3e-05 22.6 0.8 0.032 14.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 EGG18231.1 - 0.0001 22.0 1.2 0.0045 16.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 EGG18231.1 - 0.0001 22.3 9.4 0.025 14.5 0.3 4.0 5 0 0 5 5 3 2 Rad17 P-loop domain AAA_18 PF13238.6 EGG18231.1 - 0.00013 22.5 10.4 0.16 12.5 0.0 4.1 4 0 0 4 4 3 2 AAA domain AAA_21 PF13304.6 EGG18231.1 - 0.00017 21.5 0.0 0.89 9.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 EGG18231.1 - 0.00017 21.6 0.8 0.025 14.6 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EGG18231.1 - 0.00039 20.2 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 EGG18231.1 - 0.00045 19.9 0.7 0.00045 19.9 0.7 3.0 2 0 0 2 2 1 1 Plant PDR ABC transporter associated AAA_28 PF13521.6 EGG18231.1 - 0.00058 20.1 3.0 0.5 10.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EGG18231.1 - 0.00099 18.7 0.7 0.084 12.4 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region SMC_N PF02463.19 EGG18231.1 - 0.0014 18.1 9.1 0.0024 17.4 0.3 3.6 4 0 0 4 4 3 1 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 EGG18231.1 - 0.0014 18.6 1.5 0.18 11.7 0.0 2.9 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EGG18231.1 - 0.0019 18.2 0.8 0.34 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EGG18231.1 - 0.0021 18.1 0.1 1.6 8.8 0.1 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF815 PF05673.13 EGG18231.1 - 0.0026 17.0 0.3 0.53 9.4 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EGG18231.1 - 0.0035 17.1 0.1 2.9 7.6 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein PduV-EutP PF10662.9 EGG18231.1 - 0.013 15.3 1.5 0.86 9.3 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 EGG18231.1 - 0.014 15.5 0.3 4.1 7.4 0.0 3.4 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 EGG18231.1 - 0.014 15.7 0.2 0.54 10.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain PDR_CDR PF06422.12 EGG18231.1 - 0.016 15.1 0.1 0.016 15.1 0.1 3.4 4 0 0 4 4 2 0 CDR ABC transporter RuvB_N PF05496.12 EGG18231.1 - 0.017 14.9 0.4 0.71 9.6 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 EGG18231.1 - 0.02 14.5 2.6 2.1 7.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 EGG18231.1 - 0.022 14.5 0.1 0.25 11.0 0.1 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 EGG18231.1 - 0.022 13.8 0.8 0.14 11.2 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 EGG18231.1 - 0.024 14.3 0.2 10 5.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 EGG18231.1 - 0.031 14.5 4.0 2.6 8.3 0.0 3.6 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase Peptidase_M56 PF05569.11 EGG18231.1 - 0.057 12.6 3.9 0.11 11.7 0.2 2.7 3 0 0 3 3 3 0 BlaR1 peptidase M56 NB-ARC PF00931.22 EGG18231.1 - 0.1 11.8 2.4 5.5 6.1 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain DnaB_C PF03796.15 EGG18231.1 - 0.14 11.4 2.5 1 8.6 0.0 2.8 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 EGG18231.1 - 0.33 10.3 3.0 1.4 8.2 0.3 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 EGG18231.1 - 0.37 10.7 0.8 7.1 6.5 0.1 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 EGG18231.1 - 0.54 10.7 25.3 1.1 9.7 3.8 4.3 3 1 1 4 4 3 0 AAA domain SRP54 PF00448.22 EGG18231.1 - 0.62 9.7 3.5 9.8 5.7 0.3 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 EGG18231.1 - 1.2 9.6 3.6 21 5.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain ABC2_membrane PF01061.24 EGG18232.1 - 1.8e-83 279.1 56.8 3.3e-48 163.9 20.6 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGG18232.1 - 6.5e-42 143.3 12.4 5.5e-22 78.8 0.0 3.3 4 0 0 4 4 2 2 ABC transporter AAA_22 PF13401.6 EGG18232.1 - 2.1e-09 37.7 0.5 0.00035 20.9 0.1 3.2 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EGG18232.1 - 8.9e-09 36.0 6.3 5.6e-05 23.7 0.1 3.8 4 0 0 4 4 2 2 AAA domain RsgA_GTPase PF03193.16 EGG18232.1 - 1.4e-08 34.8 1.0 0.0029 17.5 0.0 3.2 2 1 1 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 EGG18232.1 - 2.2e-08 34.7 0.1 0.0081 16.6 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.6 EGG18232.1 - 3.1e-07 30.2 0.0 0.019 14.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGG18232.1 - 1.3e-06 28.7 0.0 0.057 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EGG18232.1 - 1.3e-06 28.5 2.2 0.2 11.4 0.0 4.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EGG18232.1 - 2.3e-06 27.9 0.3 0.0092 16.2 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGG18232.1 - 2.4e-06 27.2 0.5 0.0048 16.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGG18232.1 - 6.5e-06 26.5 0.0 0.17 12.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase ABC2_membrane_3 PF12698.7 EGG18232.1 - 1.2e-05 24.6 10.3 1.2e-05 24.6 10.3 4.3 4 1 0 4 4 3 1 ABC-2 family transporter protein AAA PF00004.29 EGG18232.1 - 1.7e-05 25.3 1.9 0.0052 17.2 0.8 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGG18232.1 - 5.7e-05 23.1 4.9 0.038 13.9 0.2 2.8 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_30 PF13604.6 EGG18232.1 - 6.1e-05 22.8 0.0 0.089 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGG18232.1 - 0.00012 22.1 0.3 0.073 13.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 EGG18232.1 - 0.0012 18.9 0.6 0.19 11.7 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EGG18232.1 - 0.0015 18.3 0.2 1.1 8.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 EGG18232.1 - 0.002 17.9 1.6 0.01 15.6 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Roc PF08477.13 EGG18232.1 - 0.0031 17.7 0.1 1 9.6 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 EGG18232.1 - 0.0031 16.7 0.0 1.1 8.4 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EGG18232.1 - 0.0043 17.0 2.5 0.59 10.1 0.2 3.4 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGG18232.1 - 0.0046 16.5 0.3 0.21 11.1 0.1 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region PDR_CDR PF06422.12 EGG18232.1 - 0.0062 16.4 1.1 6 6.8 0.5 3.2 2 0 0 2 2 2 0 CDR ABC transporter SMC_N PF02463.19 EGG18232.1 - 0.0064 15.9 1.1 0.0064 15.9 1.1 4.1 4 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 EGG18232.1 - 0.0065 15.7 0.2 1.1 8.4 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain PDR_assoc PF08370.11 EGG18232.1 - 0.01 15.5 1.1 0.37 10.6 0.0 3.2 2 0 0 2 2 2 0 Plant PDR ABC transporter associated IstB_IS21 PF01695.17 EGG18232.1 - 0.011 15.5 0.0 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.6 EGG18232.1 - 0.012 16.1 2.2 2 8.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 EGG18232.1 - 0.015 15.4 5.1 1.9 8.6 0.1 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase RuvB_N PF05496.12 EGG18232.1 - 0.018 14.8 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 EGG18232.1 - 0.022 14.4 6.4 0.39 10.3 0.4 3.0 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EGG18232.1 - 0.023 14.0 0.0 3.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.6 EGG18232.1 - 0.029 14.4 6.4 0.48 10.5 0.0 4.1 5 0 0 5 5 3 0 AAA domain ATP-synt_ab PF00006.25 EGG18232.1 - 0.035 13.8 0.0 0.73 9.4 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase3 PF18751.1 EGG18232.1 - 0.037 13.9 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 EGG18232.1 - 0.077 13.3 0.3 0.84 10.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGG18232.1 - 0.17 11.6 5.3 0.66 9.7 0.3 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 EGG18232.1 - 0.2 11.5 2.2 13 5.7 0.2 3.3 3 0 0 3 3 3 0 NTPase SRP54 PF00448.22 EGG18232.1 - 2.5 7.7 4.9 6 6.4 0.7 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Myosin_head PF00063.21 EGG18235.1 - 1.9e-283 941.8 3.5 1.9e-283 941.8 3.5 3.3 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 EGG18235.1 - 3.2e-67 227.3 349.3 1.4e-38 132.5 163.5 4.1 1 1 2 3 3 3 2 Myosin tail Myosin_N PF02736.19 EGG18235.1 - 1.4e-08 34.4 2.4 5.1e-08 32.6 2.4 2.1 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain BRE1 PF08647.11 EGG18235.1 - 0.00012 22.0 20.1 0.00012 22.0 20.1 17.0 4 3 13 17 17 17 2 BRE1 E3 ubiquitin ligase Filament PF00038.21 EGG18235.1 - 0.0038 16.9 23.1 0.0038 16.9 23.1 11.8 1 1 7 9 9 9 4 Intermediate filament protein IQ PF00612.27 EGG18235.1 - 0.0079 15.9 1.1 0.0079 15.9 1.1 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.6 EGG18235.1 - 0.28 11.4 0.0 0.28 11.4 0.0 5.6 4 2 2 7 7 7 0 AAA domain GST_C_3 PF14497.6 EGG18238.1 - 6.4e-12 45.5 0.0 8.2e-11 42.0 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG18238.1 - 3.5e-10 40.0 0.0 7.7e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG18238.1 - 5e-09 36.1 0.0 1.3e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pox_A32 PF04665.12 EGG18238.1 - 0.016 14.7 0.1 0.029 13.8 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein PrgU PF09627.10 EGG18240.1 - 0.001 19.0 5.4 0.0012 18.8 0.5 2.4 2 0 0 2 2 2 1 PrgU-like protein TPK_catalytic PF04263.16 EGG18240.1 - 0.046 13.8 0.5 0.12 12.4 0.5 1.7 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Tir_receptor_C PF07489.11 EGG18241.1 - 0.0072 16.3 1.9 0.011 15.7 1.9 1.2 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) C-terminus Post_transc_reg PF13797.6 EGG18241.1 - 0.18 11.7 0.2 0.71 9.8 0.0 2.0 2 0 0 2 2 2 0 Post-transcriptional regulator GST_C PF00043.25 EGG18242.1 - 0.00055 20.1 0.1 0.00065 19.9 0.1 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG18242.1 - 0.00058 20.0 0.0 0.00063 19.9 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG18242.1 - 0.0022 18.0 0.1 0.0026 17.7 0.1 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SET PF00856.28 EGG18244.1 - 4.6e-05 23.9 0.7 0.00012 22.5 0.0 2.0 2 0 0 2 2 2 1 SET domain zf-TRAF PF02176.18 EGG18247.1 - 0.18 12.5 5.7 0.91 10.3 0.6 2.5 2 0 0 2 2 2 0 TRAF-type zinc finger L_lac_phage_MSP PF06488.11 EGG18249.1 - 0.15 11.3 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Phage tail tube protein bZIP_1 PF00170.21 EGG18250.1 - 0.0019 18.2 22.2 0.13 12.4 0.4 4.8 3 1 1 4 4 4 2 bZIP transcription factor ADIP PF11559.8 EGG18250.1 - 0.014 15.5 10.1 0.014 15.5 10.1 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1192 PF06698.11 EGG18250.1 - 0.038 14.0 8.3 0.33 11.1 2.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TSC22 PF01166.18 EGG18250.1 - 0.062 13.6 15.1 1.2 9.4 0.4 4.1 4 0 0 4 4 4 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 EGG18250.1 - 0.094 12.6 13.1 9.3 6.2 0.1 4.7 4 1 0 4 4 4 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 EGG18250.1 - 0.18 11.6 35.8 0.26 11.1 2.6 4.6 1 1 4 5 5 5 0 Septum formation initiator JIP_LZII PF16471.5 EGG18250.1 - 0.2 11.9 27.0 2.7 8.3 1.0 4.6 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II TRPM_tetra PF16519.5 EGG18250.1 - 0.28 11.3 8.0 2.9 8.1 2.6 3.3 3 0 0 3 3 3 0 Tetramerisation domain of TRPM ZapB PF06005.12 EGG18250.1 - 0.43 11.1 37.4 0.15 12.5 6.7 4.6 1 1 2 3 3 3 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 EGG18250.1 - 1.1 9.4 39.5 54 3.9 6.3 4.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding VGPC1_C PF16799.5 EGG18250.1 - 1.1 9.3 8.6 1.2 9.1 0.1 3.1 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 ATP-synt_F6 PF05511.11 EGG18250.1 - 2.5 8.6 6.7 0.33 11.4 1.0 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 HOOK PF05622.12 EGG18250.1 - 3.5 5.6 35.1 0.91 7.6 23.1 2.3 1 1 1 2 2 2 0 HOOK protein DUF4407 PF14362.6 EGG18250.1 - 3.7 6.8 26.3 3.2 7.0 1.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 EGG18250.1 - 5.7 7.1 36.3 2.1 8.6 23.1 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) NRBF2 PF08961.10 EGG18250.1 - 6.6 6.3 24.4 1.8 8.1 5.3 2.9 1 1 0 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator DUF16 PF01519.16 EGG18250.1 - 8.1 7.0 33.8 7.5 7.1 5.3 3.7 1 1 1 3 3 3 0 Protein of unknown function DUF16 GST_N PF02798.20 EGG18253.1 - 6e-15 55.4 0.0 1.2e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGG18253.1 - 2e-14 53.7 0.0 3.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGG18253.1 - 5.1e-12 45.8 0.0 8.8e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG18253.1 - 2.4e-11 43.7 0.0 4.3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGG18253.1 - 5.2e-11 42.7 0.0 1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGG18253.1 - 2e-10 40.6 1.1 4.1e-10 39.5 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGG18253.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tubulin PF00091.25 EGG18254.1 - 2.2e-63 214.0 0.0 8.2e-63 212.2 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGG18254.1 - 2.7e-46 156.8 0.2 4.6e-46 156.1 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGG18254.1 - 0.00022 20.9 0.0 0.00062 19.5 0.0 1.8 1 0 0 1 1 1 1 Tubulin domain B9-C2 PF07162.11 EGG18255.1 - 0.097 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein zf-RVT PF13966.6 EGG18255.1 - 0.14 12.9 2.6 0.35 11.6 0.0 2.7 2 1 0 2 2 2 0 zinc-binding in reverse transcriptase Nup88 PF10168.9 EGG18257.1 - 0.048 11.5 0.1 0.049 11.5 0.1 1.0 1 0 0 1 1 1 0 Nuclear pore component Sacchrp_dh_C PF16653.5 EGG18260.1 - 7.4e-80 268.9 0.0 3.1e-79 266.8 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 EGG18260.1 - 2.1e-26 92.8 0.0 6.4e-26 91.3 0.0 1.9 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 EGG18260.1 - 3.1e-23 82.4 0.1 6e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 EGG18260.1 - 2.4e-09 36.8 0.0 9e-06 25.1 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EGG18260.1 - 4.5e-05 23.7 0.2 0.0001 22.6 0.2 1.6 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 EGG18260.1 - 0.0005 20.2 0.1 0.0012 18.9 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 EGG18260.1 - 0.0039 17.3 0.1 0.0071 16.5 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus UDPG_MGDP_dh_N PF03721.14 EGG18260.1 - 0.0065 16.1 0.2 0.013 15.1 0.2 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3Beta_HSD PF01073.19 EGG18260.1 - 0.017 14.1 0.3 0.04 12.9 0.3 1.6 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGG18260.1 - 0.023 14.6 0.1 0.05 13.5 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H-binding ThiF PF00899.21 EGG18260.1 - 0.074 12.4 0.0 0.64 9.3 0.0 2.4 2 1 1 3 3 3 0 ThiF family GFO_IDH_MocA PF01408.22 EGG18260.1 - 0.12 13.2 0.0 0.24 12.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold URO-D PF01208.17 EGG18261.1 - 5.6e-127 423.7 0.0 6.2e-127 423.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) MoaE PF02391.17 EGG18262.1 - 3.2e-21 75.7 0.0 3.9e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 MoaE protein tRNA-synt_2d PF01409.20 EGG18263.1 - 2.1e-51 174.7 3.1 5.2e-31 108.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EGG18263.1 - 1.2e-22 80.1 0.1 9.9e-22 77.2 0.0 2.5 3 0 0 3 3 3 1 Ferredoxin-fold anticodon binding domain Ank_2 PF12796.7 EGG18264.1 - 9.3e-17 61.4 16.5 1.3e-05 25.7 0.1 6.8 5 2 3 8 8 8 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18264.1 - 2.1e-14 53.6 11.7 0.0015 19.1 0.1 8.6 8 1 1 9 9 9 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18264.1 - 2.5e-07 30.9 6.1 0.11 12.8 0.0 6.6 5 2 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18264.1 - 0.00016 21.8 13.0 68 4.5 0.0 9.4 9 1 1 10 10 10 0 Ankyrin repeat GCK PF07802.11 EGG18265.1 - 2.4e-06 27.9 0.4 4.2e-06 27.1 0.3 1.5 1 1 1 2 2 2 1 GCK domain CHCH PF06747.13 EGG18265.1 - 0.08 13.1 1.8 0.13 12.4 1.8 1.4 1 0 0 1 1 1 0 CHCH domain DNA_pol_E_B PF04042.16 EGG18266.1 - 4.5e-45 153.6 1.5 6.1e-45 153.2 0.8 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 EGG18266.1 - 8.3e-06 26.0 0.3 0.00024 21.3 0.3 2.7 1 1 0 1 1 1 1 DNA polymerases epsilon N terminal TT_ORF1 PF02956.14 EGG18266.1 - 0.19 10.4 1.1 0.27 9.9 1.1 1.2 1 0 0 1 1 1 0 TT viral orf 1 MMgT PF10270.9 EGG18267.1 - 0.098 13.0 0.1 3.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Membrane magnesium transporter TPR_MLP1_2 PF07926.12 EGG18269.1 - 2.1e-30 105.4 18.5 2.1e-30 105.4 18.5 17.0 9 3 11 20 20 20 8 TPR/MLP1/MLP2-like protein Metallophos PF00149.28 EGG18270.1 - 1.2e-18 68.3 0.9 2.8e-18 67.2 0.3 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EGG18270.1 - 4e-16 59.6 0.2 3.1e-14 53.6 0.0 2.5 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EGG18270.1 - 6.5e-12 45.9 2.6 1.2e-11 45.0 0.1 2.6 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Adap_comp_sub PF00928.21 EGG18271.1 - 1.2e-19 70.7 0.2 2.3e-19 69.8 0.2 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family zf-NF-X1 PF01422.17 EGG18272.1 - 9e-12 44.8 205.5 3.9e-05 23.6 14.3 12.8 12 1 1 13 13 13 7 NF-X1 type zinc finger polyprenyl_synt PF00348.17 EGG18273.1 - 1.2e-58 198.2 0.0 1.4e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase NYN PF01936.18 EGG18273.1 - 0.014 15.9 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 0 NYN domain ExbD PF02472.16 EGG18274.1 - 0.00093 19.4 0.0 0.23 11.6 0.0 2.3 2 0 0 2 2 2 2 Biopolymer transport protein ExbD/TolR F-box PF00646.33 EGG18274.1 - 0.0029 17.4 0.2 0.0069 16.2 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGG18274.1 - 0.0039 17.0 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like Acyl_transf_3 PF01757.22 EGG18275.1 - 3.5e-17 62.5 33.8 3.5e-17 62.5 33.8 1.6 2 0 0 2 2 2 1 Acyltransferase family PHD PF00628.29 EGG18276.1 - 1.6e-13 50.3 28.2 2.2e-07 30.7 14.8 2.5 2 0 0 2 2 2 2 PHD-finger FHA PF00498.26 EGG18276.1 - 4.9e-09 36.4 1.1 8.8e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EGG18276.1 - 0.00012 22.4 0.0 0.00039 20.7 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PHD_2 PF13831.6 EGG18276.1 - 0.0026 17.3 15.4 0.22 11.1 1.3 2.6 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 EGG18276.1 - 0.015 15.6 15.1 0.082 13.2 2.0 3.1 2 0 0 2 2 2 0 PHD-like zinc-binding domain Caldesmon PF02029.15 EGG18276.1 - 0.022 13.6 64.5 0.015 14.1 6.5 3.1 3 0 0 3 3 3 0 Caldesmon zf-HC5HC2H_2 PF13832.6 EGG18276.1 - 1.2 9.4 10.3 5.8 7.1 1.1 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain TPR_8 PF13181.6 EGG18277.1 - 2.4e-05 24.2 2.5 0.13 12.5 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG18277.1 - 0.00021 21.9 0.1 0.0018 18.9 0.0 2.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG18277.1 - 0.00029 21.3 2.2 0.025 15.1 0.2 2.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG18277.1 - 0.00054 19.9 0.7 2.6 8.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG18277.1 - 0.002 17.9 0.8 4.7 7.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 EGG18277.1 - 0.0026 16.7 0.5 0.0042 16.1 0.5 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 Ca_bind_SSO6904 PF18249.1 EGG18277.1 - 0.051 13.9 0.3 0.31 11.4 0.3 2.4 1 1 0 1 1 1 0 Calcium binding protein SSO6904 Lactamase_B_2 PF12706.7 EGG18278.1 - 1.1e-20 74.1 0.0 3.7e-16 59.3 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EGG18278.1 - 1e-13 50.7 0.0 2.6e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 EGG18278.1 - 0.069 13.2 0.0 0.29 11.1 0.5 1.7 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Spt20 PF12090.8 EGG18278.1 - 0.11 12.1 42.0 0.0094 15.6 8.7 3.3 3 0 0 3 3 3 0 Spt20 family TFIIA PF03153.13 EGG18278.1 - 9.3 6.1 40.0 0.78 9.7 12.6 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit WRKY PF03106.15 EGG18279.1 - 1.1e-08 35.1 1.4 5.7e-08 32.9 1.4 2.3 1 0 0 1 1 1 1 WRKY DNA -binding domain INSC_LBD PF16748.5 EGG18279.1 - 0.04 13.4 0.0 0.09 12.2 0.0 1.6 1 0 0 1 1 1 0 Inscuteable LGN-binding domain DUF3439 PF11921.8 EGG18279.1 - 0.41 10.6 11.2 0.67 9.9 2.7 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Peptidase_C15 PF01470.17 EGG18280.1 - 4.2e-12 46.7 0.2 1.6e-08 35.0 0.0 2.1 1 1 1 2 2 2 2 Pyroglutamyl peptidase NRDE-2 PF08424.10 EGG18280.1 - 0.013 14.6 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference MRG PF05712.13 EGG18281.1 - 6e-31 107.3 0.9 1.8e-30 105.7 0.9 1.9 1 1 0 1 1 1 1 MRG Tudor-knot PF11717.8 EGG18281.1 - 7.8e-10 38.5 5.8 1.4e-09 37.7 5.8 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Sporozoite_P67 PF05642.11 EGG18281.1 - 0.032 12.3 3.6 0.039 12.1 3.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.9 EGG18281.1 - 0.036 12.6 0.3 0.03 12.9 0.3 1.1 1 0 0 1 1 1 0 Macoilin family Mucin PF01456.17 EGG18281.1 - 0.1 12.6 10.4 0.15 12.1 10.4 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 EGG18281.1 - 0.58 8.3 18.4 0.71 8.0 18.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Period_C PF12114.8 EGG18281.1 - 3.9 7.0 11.8 6.2 6.4 11.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SprA-related PF12118.8 EGG18281.1 - 6.1 5.9 11.6 8.6 5.4 11.6 1.1 1 0 0 1 1 1 0 SprA-related family CCDC106 PF15794.5 EGG18281.1 - 8.1 6.1 10.5 14 5.3 10.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 adh_short PF00106.25 EGG18282.1 - 1.4e-46 158.4 0.0 1.9e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG18282.1 - 7.9e-33 113.9 0.0 1.2e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG18282.1 - 2.6e-12 47.0 0.0 4.2e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG18282.1 - 2.7e-08 33.6 0.1 1.5e-07 31.2 0.0 2.2 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG18282.1 - 8.6e-06 25.4 0.3 5.7e-05 22.7 0.2 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGG18282.1 - 0.00032 19.9 0.0 0.0005 19.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Alpha-mann_mid PF09261.11 EGG18283.1 - 0.11 12.7 0.2 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 Alpha mannosidase middle domain Acyl_transf_3 PF01757.22 EGG18284.1 - 1.3e-21 77.1 40.5 2.5e-21 76.1 40.5 1.4 1 0 0 1 1 1 1 Acyltransferase family Tox-WTIP PF15654.6 EGG18284.1 - 0.17 12.3 0.1 1.8 9.0 0.0 2.5 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif OTU PF02338.19 EGG18285.1 - 5.7e-07 30.1 1.3 8.4e-07 29.5 0.1 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease MAGE_N PF12440.8 EGG18285.1 - 3 8.6 18.4 0.077 13.7 6.6 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Membralin PF09746.9 EGG18285.1 - 3.8 6.4 10.2 0.35 9.9 4.4 2.1 3 0 0 3 3 3 0 Tumour-associated protein Dicty_REP PF05086.12 EGG18285.1 - 7.6 4.4 30.5 3.8 5.4 15.2 2.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Gar1 PF04410.14 EGG18286.1 - 2.9e-28 98.6 10.3 1.3e-17 64.0 0.2 5.3 4 1 3 7 7 7 2 Gar1/Naf1 RNA binding region DUF4199 PF13858.6 EGG18286.1 - 8.3 6.8 5.8 46 4.4 5.8 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Hydrolase_4 PF12146.8 EGG18287.1 - 5.9e-61 205.8 0.0 7.3e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG18287.1 - 3.6e-10 39.9 0.2 7.4e-07 29.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGG18287.1 - 2e-08 34.3 0.3 0.01 15.6 0.1 2.8 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGG18287.1 - 7.5e-08 33.2 0.0 1.1e-07 32.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGG18287.1 - 0.0023 17.4 0.0 0.041 13.4 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EGG18287.1 - 0.045 13.3 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.13 EGG18287.1 - 0.063 12.9 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 EGG18287.1 - 0.1 12.2 0.0 7 6.1 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.25 EGG18288.1 - 3.3e-21 75.7 0.0 2.4e-20 72.9 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) CBM49 PF09478.10 EGG18288.1 - 3e-05 24.2 0.3 9.6e-05 22.6 0.3 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF2974 PF11187.8 EGG18288.1 - 0.00019 21.1 0.4 0.001 18.7 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EGG18288.1 - 0.15 12.6 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family SUIM_assoc PF16619.5 EGG18290.1 - 0.0053 16.8 1.8 0.0053 16.8 1.8 10.0 8 3 1 9 9 9 2 Unstructured region C-term to UIM in Ataxin3 AAA PF00004.29 EGG18291.1 - 7.7e-52 175.2 0.0 8.7e-37 126.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG18291.1 - 5.1e-10 40.0 0.0 0.00062 20.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGG18291.1 - 4.6e-09 36.7 0.2 0.0017 18.6 0.0 3.7 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.14 EGG18291.1 - 9.9e-09 35.3 0.0 0.0016 18.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGG18291.1 - 1.1e-07 32.2 0.0 0.0081 16.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGG18291.1 - 1.2e-07 32.3 0.1 0.0083 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EGG18291.1 - 1.8e-07 31.4 0.0 7.4e-05 22.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 EGG18291.1 - 2.2e-07 30.6 0.1 5e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGG18291.1 - 3.7e-07 30.0 0.0 0.02 14.6 0.1 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGG18291.1 - 9.2e-07 29.2 0.0 0.041 14.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 EGG18291.1 - 7.8e-06 25.4 0.7 0.011 15.1 0.2 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGG18291.1 - 1.5e-05 24.7 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 EGG18291.1 - 1.9e-05 24.7 0.0 0.05 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EGG18291.1 - 2.7e-05 24.7 0.1 0.29 11.7 0.1 2.7 2 0 0 2 2 2 2 ABC transporter AAA_7 PF12775.7 EGG18291.1 - 3.8e-05 23.3 0.1 0.031 13.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_3 PF07726.11 EGG18291.1 - 4e-05 23.5 0.0 0.22 11.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EGG18291.1 - 4.2e-05 23.4 0.0 0.21 11.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 EGG18291.1 - 5e-05 22.7 0.1 0.0042 16.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 EGG18291.1 - 5.4e-05 23.2 1.6 0.58 10.1 0.1 3.5 2 1 0 3 3 3 2 NACHT domain TIP49 PF06068.13 EGG18291.1 - 7.8e-05 22.0 0.0 0.067 12.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_28 PF13521.6 EGG18291.1 - 0.00011 22.5 0.0 0.49 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EGG18291.1 - 0.00012 22.0 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EGG18291.1 - 0.00024 20.5 0.2 0.087 12.2 0.0 2.8 2 0 0 2 2 2 1 KaiC AAA_24 PF13479.6 EGG18291.1 - 0.00032 20.5 0.2 0.63 9.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain CDC48_N PF02359.18 EGG18291.1 - 0.00041 20.5 0.0 0.0022 18.1 0.0 2.3 1 1 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_25 PF13481.6 EGG18291.1 - 0.00097 18.8 0.1 1.9 8.1 0.2 2.7 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 EGG18291.1 - 0.0011 18.2 0.2 0.85 8.7 0.2 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_11 PF13086.6 EGG18291.1 - 0.0033 17.3 0.1 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EGG18291.1 - 0.0069 16.8 0.1 0.77 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EGG18291.1 - 0.01 15.6 0.0 0.83 9.3 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 EGG18291.1 - 0.01 16.0 0.0 4.8 7.3 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF2075 PF09848.9 EGG18291.1 - 0.015 14.6 0.3 1.2 8.3 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.10 EGG18291.1 - 0.017 14.6 0.0 6.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 CPT PF07931.12 EGG18291.1 - 0.018 14.9 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 EGG18291.1 - 0.023 13.8 0.0 2.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 EGG18291.1 - 0.024 14.4 0.0 0.57 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGG18291.1 - 0.03 14.2 1.1 2.8 7.8 0.1 3.0 3 1 0 3 3 2 0 Rad17 P-loop domain DUF815 PF05673.13 EGG18291.1 - 0.032 13.4 0.2 0.46 9.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EGG18291.1 - 0.043 13.7 0.0 8.5 6.3 0.0 2.9 2 0 0 2 2 2 0 NTPase Torsin PF06309.11 EGG18291.1 - 0.063 13.4 0.0 6.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Torsin AAA_23 PF13476.6 EGG18291.1 - 0.082 13.4 1.4 0.71 10.3 0.0 2.7 2 1 0 3 3 2 0 AAA domain AAA_19 PF13245.6 EGG18291.1 - 0.087 13.2 0.4 1.6 9.1 0.2 2.5 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 EGG18291.1 - 0.088 12.9 0.1 2 8.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.16 EGG18291.1 - 0.098 12.1 0.0 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Cytidylate_kin PF02224.18 EGG18291.1 - 0.11 12.2 0.1 14 5.4 0.1 2.4 2 0 0 2 2 2 0 Cytidylate kinase TniB PF05621.11 EGG18291.1 - 0.12 11.7 0.1 12 5.3 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein AAA_29 PF13555.6 EGG18291.1 - 0.15 11.9 0.6 8.6 6.2 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 EGG18292.1 - 1.8e-51 174.0 0.0 8.7e-37 126.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG18292.1 - 6.5e-10 39.7 0.0 0.00074 19.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGG18292.1 - 6.5e-09 36.2 0.2 0.0017 18.6 0.0 3.6 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.14 EGG18292.1 - 1.1e-08 35.1 0.0 0.0016 18.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGG18292.1 - 4.5e-08 33.7 0.0 0.0083 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGG18292.1 - 1.1e-07 32.2 0.0 0.0081 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EGG18292.1 - 1.7e-07 31.5 0.0 7.3e-05 22.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 EGG18292.1 - 2e-07 30.7 0.1 5e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGG18292.1 - 4.3e-07 29.8 0.0 0.02 14.6 0.1 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGG18292.1 - 5.9e-07 29.8 0.0 0.037 14.4 0.0 3.2 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 EGG18292.1 - 6.5e-06 25.7 0.4 0.011 15.1 0.2 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGG18292.1 - 1.6e-05 24.7 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 EGG18292.1 - 1.8e-05 25.3 0.1 0.29 11.7 0.1 2.8 2 0 0 2 2 2 2 ABC transporter AAA_3 PF07726.11 EGG18292.1 - 3.3e-05 23.8 0.0 0.22 11.4 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EGG18292.1 - 3.5e-05 23.6 0.0 0.21 11.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EGG18292.1 - 3.5e-05 23.4 0.1 0.031 13.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 EGG18292.1 - 4.6e-05 22.8 0.2 0.0037 16.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin TIP49 PF06068.13 EGG18292.1 - 7e-05 22.2 0.0 0.067 12.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EGG18292.1 - 9.1e-05 22.5 0.0 0.24 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGG18292.1 - 9.5e-05 22.4 1.4 0.48 10.3 0.0 3.4 2 1 1 3 3 3 2 NACHT domain AAA_28 PF13521.6 EGG18292.1 - 0.0001 22.6 0.0 0.46 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EGG18292.1 - 0.00012 22.1 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE CDC48_N PF02359.18 EGG18292.1 - 0.00014 22.0 0.0 0.00075 19.6 0.0 2.3 1 1 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_24 PF13479.6 EGG18292.1 - 0.00027 20.7 0.0 0.63 9.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 EGG18292.1 - 0.00029 20.3 0.2 0.087 12.2 0.0 2.6 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 EGG18292.1 - 0.0011 18.6 0.1 1.9 8.1 0.2 2.6 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 EGG18292.1 - 0.0012 18.1 0.2 0.85 8.8 0.2 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_11 PF13086.6 EGG18292.1 - 0.0032 17.3 0.1 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EGG18292.1 - 0.0065 16.9 0.1 0.77 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EGG18292.1 - 0.0069 16.1 0.0 0.58 9.8 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 EGG18292.1 - 0.01 16.0 0.0 4.9 7.3 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Rad17 PF03215.15 EGG18292.1 - 0.014 15.4 0.3 2.2 8.1 0.0 3.1 3 0 0 3 3 2 0 Rad17 P-loop domain DUF2075 PF09848.9 EGG18292.1 - 0.014 14.7 0.2 1.2 8.3 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.12 EGG18292.1 - 0.018 14.9 0.1 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 EGG18292.1 - 0.018 14.5 0.0 6.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Parvo_NS1 PF01057.17 EGG18292.1 - 0.024 13.7 0.0 2.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 EGG18292.1 - 0.024 14.3 0.0 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGG18292.1 - 0.032 13.4 0.2 0.44 9.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 EGG18292.1 - 0.04 14.4 0.2 0.63 10.5 0.0 2.6 1 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGG18292.1 - 0.048 13.6 0.0 8.5 6.3 0.0 2.8 2 0 0 2 2 2 0 NTPase Torsin PF06309.11 EGG18292.1 - 0.057 13.5 0.0 6.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Torsin AAA_19 PF13245.6 EGG18292.1 - 0.087 13.2 0.3 1.6 9.1 0.2 2.5 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EGG18292.1 - 0.091 12.5 0.1 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase SKI PF01202.22 EGG18292.1 - 0.092 12.9 0.1 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.16 EGG18292.1 - 0.1 12.1 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein TniB PF05621.11 EGG18292.1 - 0.12 11.8 0.1 12 5.3 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein AAA_29 PF13555.6 EGG18292.1 - 0.14 11.9 0.6 8.6 6.2 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Glyco_hydro_15 PF00723.21 EGG18293.1 - 1.2e-15 57.3 0.0 1.2e-12 47.4 0.0 2.2 1 1 0 2 2 2 2 Glycosyl hydrolases family 15 SAP PF02037.27 EGG18294.1 - 0.00037 20.2 1.5 0.00052 19.7 0.6 1.7 2 0 0 2 2 2 1 SAP domain PHO4 PF01384.20 EGG18295.1 - 0.073 12.1 1.4 0.082 11.9 1.4 1.3 1 0 0 1 1 1 0 Phosphate transporter family Cation_ATPase_C PF00689.21 EGG18295.1 - 0.38 10.4 9.4 0.59 9.8 9.5 1.4 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus ABC_tran PF00005.27 EGG18296.1 - 1.1e-29 103.7 0.0 2.8e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGG18296.1 - 1e-12 47.9 27.6 1e-12 47.9 27.6 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGG18296.1 - 9.6e-09 35.5 0.0 9.9e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGG18296.1 - 0.00016 21.6 0.1 0.00048 20.1 0.1 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGG18296.1 - 0.02 15.3 0.0 0.045 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EGG18296.1 - 0.021 15.3 1.9 0.034 14.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGG18296.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 EGG18296.1 - 0.04 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4162 PF13732.6 EGG18296.1 - 0.043 14.5 0.0 0.12 13.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) SMC_N PF02463.19 EGG18296.1 - 0.051 13.0 0.4 9.5 5.6 0.2 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain TsaE PF02367.17 EGG18296.1 - 0.08 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EGG18296.1 - 0.098 12.9 0.0 0.32 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGG18296.1 - 0.12 12.4 0.4 0.4 10.8 0.1 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EGG18297.1 - 1.6e-28 99.9 0.0 3.6e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGG18297.1 - 2.3e-15 56.6 61.7 8e-15 54.8 61.7 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGG18297.1 - 1.2e-14 54.9 1.5 3.4e-10 40.2 0.0 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG18297.1 - 0.0012 18.4 1.3 0.068 12.6 0.1 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EGG18297.1 - 0.0025 17.8 1.3 0.0033 17.4 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain Tmemb_9 PF05434.11 EGG18297.1 - 0.051 13.5 0.3 0.17 11.8 0.3 1.8 1 0 0 1 1 1 0 TMEM9 Cnd1_N PF12922.7 EGG18297.1 - 0.065 13.1 0.4 0.18 11.7 0.2 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Secretin_N_2 PF07655.13 EGG18297.1 - 0.41 11.2 10.6 1.3 9.6 10.6 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain ABC2_membrane PF01061.24 EGG18297.1 - 1.7 8.0 39.3 0.21 11.0 27.7 2.7 3 1 0 3 3 3 0 ABC-2 type transporter SmpA_OmlA PF04355.13 EGG18298.1 - 0.0065 16.2 0.0 0.0092 15.8 0.0 1.2 1 0 0 1 1 1 1 SmpA / OmlA family WD40 PF00400.32 EGG18301.1 - 7.2e-16 58.3 27.8 6.1e-05 23.7 0.5 5.7 4 1 1 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG18301.1 - 1.6e-06 28.3 7.4 0.0016 18.7 0.5 3.4 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGG18301.1 - 0.00019 20.3 1.3 0.089 11.5 0.1 2.2 2 0 0 2 2 2 2 Nup133 N terminal like VCBS PF13517.6 EGG18301.1 - 0.13 12.8 0.2 39 4.9 0.0 2.9 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF1713 PF08213.11 EGG18302.1 - 3.3e-08 33.3 20.5 5e-08 32.7 20.5 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Nuf2 PF03800.14 EGG18303.1 - 3e-38 131.1 0.1 1.1e-37 129.2 0.1 2.1 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 EGG18303.1 - 5.5e-14 52.2 16.5 5.5e-14 52.2 16.5 3.7 2 1 1 4 4 4 2 Designed helical repeat protein 10 domain Atg14 PF10186.9 EGG18303.1 - 0.00068 18.8 9.9 0.00068 18.8 9.9 2.5 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EGG18303.1 - 0.0046 16.3 3.0 0.0046 16.3 3.0 3.6 1 1 3 4 4 4 1 TMPIT-like protein APG6_N PF17675.1 EGG18303.1 - 0.0073 16.8 7.0 0.0073 16.8 7.0 4.4 2 2 1 3 3 2 1 Apg6 coiled-coil region ATG16 PF08614.11 EGG18303.1 - 0.012 15.8 5.3 0.012 15.8 5.3 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 EGG18303.1 - 0.038 14.0 1.0 0.038 14.0 1.0 4.2 1 1 3 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 EGG18303.1 - 0.12 11.2 38.6 0.032 13.1 18.9 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like SlyX PF04102.12 EGG18303.1 - 0.16 12.6 17.5 0.8 10.4 2.5 4.2 2 2 2 4 4 4 0 SlyX YtxH PF12732.7 EGG18303.1 - 0.41 11.2 10.1 1.1e+03 0.2 10.1 3.3 1 1 0 1 1 1 0 YtxH-like protein DASH_Dad1 PF08649.10 EGG18303.1 - 0.56 10.4 7.3 0.84 9.9 1.6 3.5 2 1 1 3 3 3 0 DASH complex subunit Dad1 COX6B PF02297.17 EGG18303.1 - 0.98 9.7 4.8 1.4 9.2 0.3 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb Golgin_A5 PF09787.9 EGG18303.1 - 1.9 7.9 41.8 0.077 12.4 11.7 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 zf-C4pol PF14260.6 EGG18303.1 - 2.6 8.6 7.5 6.3 7.3 1.1 3.4 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta DUF3450 PF11932.8 EGG18303.1 - 4.4 6.5 31.5 0.18 11.1 3.6 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 EGG18303.1 - 5.2 5.9 39.9 0.21 10.4 9.9 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2703 PF10865.8 EGG18303.1 - 5.3 7.3 11.8 0.61 10.3 1.2 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF2703) Frizzled PF01534.17 EGG18305.1 - 2.3e-08 33.5 22.6 4.2e-08 32.6 22.6 1.4 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 EGG18305.1 - 1.4e-06 27.8 16.7 1.4e-06 27.8 16.7 1.7 2 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) Fz PF01392.22 EGG18305.1 - 8.7e-05 23.1 3.7 8.7e-05 23.1 3.7 1.7 2 0 0 2 2 2 1 Fz domain MS_channel PF00924.18 EGG18306.1 - 2.2e-26 92.7 1.3 2.2e-26 92.7 1.3 2.9 3 0 0 3 3 3 1 Mechanosensitive ion channel Tam41_Mmp37 PF09139.11 EGG18307.1 - 5.8e-100 334.9 4.7 9.2e-100 334.2 4.7 1.3 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial MFS_1 PF07690.16 EGG18308.1 - 4.3e-27 95.0 30.8 3.3e-23 82.2 6.8 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG18308.1 - 1.3e-14 54.0 1.1 1.3e-14 54.0 1.1 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EGG18308.1 - 0.00025 19.6 0.5 0.00046 18.7 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_32 PF13679.6 EGG18309.1 - 7.7e-25 87.7 12.4 4.3e-24 85.3 8.5 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG18309.1 - 3.4e-05 24.5 0.0 0.0001 23.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG18309.1 - 0.00022 20.8 0.2 0.00061 19.4 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 EGG18309.1 - 0.00035 20.4 0.1 0.0064 16.3 0.0 2.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EGG18309.1 - 0.00045 20.1 0.1 0.0012 18.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG18309.1 - 0.0007 19.4 1.6 0.0025 17.6 1.6 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EGG18309.1 - 0.0026 17.9 0.0 0.005 17.0 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 EGG18309.1 - 0.0053 17.5 5.7 0.023 15.4 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG18309.1 - 0.0062 17.2 0.1 0.026 15.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 EGG18309.1 - 0.012 15.2 0.4 0.028 14.0 0.4 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 EGG18309.1 - 0.017 15.0 0.8 0.042 13.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain FAM176 PF14851.6 EGG18309.1 - 0.23 11.1 11.4 0.076 12.7 4.2 2.3 2 0 0 2 2 2 0 FAM176 family ABC2_membrane_3 PF12698.7 EGG18309.1 - 0.47 9.5 6.0 4.2 6.4 0.7 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF647 PF04884.14 EGG18310.1 - 6.7e-97 323.8 0.1 8.7e-97 323.5 0.1 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis LtrA PF06772.11 EGG18310.1 - 0.099 11.8 0.2 0.15 11.3 0.2 1.2 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Autophagy_N PF03986.13 EGG18311.1 - 6e-42 142.8 2.6 6e-42 142.8 2.6 1.8 1 1 1 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EGG18311.1 - 1.2e-22 80.2 0.6 2.8e-22 79.1 0.6 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EGG18311.1 - 1.7e-13 49.8 3.9 3.2e-13 48.9 3.9 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal CRT-like PF08627.10 EGG18312.1 - 6.9e-159 528.2 22.6 8e-159 528.0 22.6 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 EGG18312.1 - 9.9e-07 28.6 3.5 9.9e-07 28.6 3.5 2.3 2 0 0 2 2 2 2 Solute carrier family 35 EamA PF00892.20 EGG18312.1 - 0.015 15.5 11.7 0.015 15.5 11.7 3.6 3 1 0 3 3 3 0 EamA-like transporter family DAGK_acc PF00609.19 EGG18313.1 - 1.2e-48 165.5 0.0 2.5e-48 164.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 EGG18313.1 - 3.3e-24 84.9 0.0 6.8e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 EGG18313.1 - 2.3e-11 43.4 20.0 1.7e-09 37.4 11.4 2.6 2 1 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) ScsC_N PF18312.1 EGG18313.1 - 0.031 14.1 0.1 0.054 13.3 0.1 1.4 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain C1_2 PF03107.16 EGG18313.1 - 0.43 10.9 13.3 0.18 12.2 7.8 2.4 2 0 0 2 2 2 0 C1 domain zf-RING_9 PF13901.6 EGG18313.1 - 6.8 6.6 14.0 2.4 8.1 7.7 2.2 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon EF-hand_6 PF13405.6 EGG18315.1 - 1.1e-07 31.2 0.4 1.1e-07 31.2 0.4 1.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGG18315.1 - 5e-07 28.8 1.7 5e-07 28.8 1.7 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EGG18315.1 - 3.2e-05 23.2 1.3 5.8e-05 22.4 1.3 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGG18315.1 - 6.1e-05 23.4 0.8 7.7e-05 23.1 0.8 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGG18315.1 - 0.0037 17.1 0.3 0.008 16.0 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain pair Dockerin_1 PF00404.18 EGG18315.1 - 0.068 13.4 0.0 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 Dockerin type I domain COMM_domain PF07258.14 EGG18316.1 - 2.9e-13 49.7 3.6 2.9e-13 49.7 3.6 5.2 6 1 0 6 6 6 1 COMM domain COMMD1_N PF17221.3 EGG18316.1 - 1.9e-06 28.1 0.9 1.9e-06 28.1 0.9 2.8 3 0 0 3 3 3 1 COMMD1 N-terminal domain Ank_2 PF12796.7 EGG18317.1 - 1.4e-11 44.8 0.0 0.005 17.4 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18317.1 - 6.2e-06 26.7 0.4 7.8 7.2 0.0 5.9 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18317.1 - 0.0003 21.0 0.0 22 6.0 0.0 6.0 5 0 0 5 5 5 1 Ankyrin repeat PCAF_N PF06466.11 EGG18317.1 - 0.04 13.5 1.8 0.42 10.2 0.1 2.5 2 0 0 2 2 2 0 PCAF (P300/CBP-associated factor) N-terminal domain Ank_5 PF13857.6 EGG18317.1 - 0.11 12.9 0.0 61 4.1 0.0 4.0 3 2 1 4 4 4 0 Ankyrin repeats (many copies) Hep_59 PF07052.11 EGG18317.1 - 0.11 13.2 0.3 0.3 11.9 0.1 1.7 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Ank_2 PF12796.7 EGG18318.1 - 2.1e-28 98.7 8.3 1.6e-08 35.0 0.0 7.6 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18318.1 - 4.9e-26 90.5 7.4 0.006 16.9 0.0 10.9 4 2 6 12 12 12 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG18318.1 - 1e-21 77.0 12.7 0.00036 21.0 0.0 9.4 5 2 5 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18318.1 - 3e-11 42.5 8.3 0.78 10.5 0.0 11.5 14 0 0 14 14 14 3 Ankyrin repeat DUF5049 PF16468.5 EGG18318.1 - 5.2e-06 26.3 5.3 1.4 8.8 0.0 7.0 4 2 3 7 7 7 2 Domain of unknown function (DUF5049) Ank PF00023.30 EGG18318.1 - 0.0022 18.4 0.1 1.3e+02 3.3 0.0 6.9 5 2 0 5 5 5 0 Ankyrin repeat AUX_IAA PF02309.16 EGG18319.1 - 3.2e-05 23.9 1.7 0.001 19.0 0.0 2.8 2 1 0 2 2 2 1 AUX/IAA family Spore_III_AF PF09581.10 EGG18319.1 - 0.35 10.9 8.2 2.1 8.4 8.2 2.1 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Prefoldin_2 PF01920.20 EGG18320.1 - 0.058 13.4 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 Prefoldin subunit PspB PF06667.12 EGG18320.1 - 0.15 12.1 0.3 0.38 10.8 0.3 1.6 1 0 0 1 1 1 0 Phage shock protein B PKcGMP_CC PF16808.5 EGG18320.1 - 0.51 10.2 2.5 0.97 9.3 2.5 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase EB PF01683.18 EGG18321.1 - 2.6 8.4 80.0 0.29 11.5 8.2 8.3 1 1 6 7 7 7 0 EB module Got1 PF04178.12 EGG18322.1 - 4.1e-30 104.5 20.6 6.7e-30 103.8 20.3 1.5 1 1 0 1 1 1 1 Got1/Sft2-like family DUF417 PF04224.12 EGG18322.1 - 0.099 12.2 5.8 0.57 9.7 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF417 COX4_pro_2 PF07835.12 EGG18322.1 - 2 8.6 7.1 1.8 8.7 1.2 2.7 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV Alg14 PF08660.11 EGG18323.1 - 1.2e-60 204.4 0.1 2.2e-60 203.6 0.1 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.16 EGG18323.1 - 5.5e-15 55.7 0.0 8.3e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain MFS_1 PF07690.16 EGG18324.1 - 3e-27 95.5 17.0 5.2e-27 94.7 16.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG18324.1 - 3.5e-07 29.5 2.8 3.5e-07 29.5 2.8 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 EGG18324.1 - 0.00015 20.4 15.5 0.0023 16.5 2.4 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein zf-LITAF-like PF10601.9 EGG18324.1 - 0.069 13.4 0.8 0.87 9.9 0.3 2.7 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain DUF2523 PF10734.9 EGG18324.1 - 2 9.0 5.6 3.1 8.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2523) LRR_8 PF13855.6 EGG18325.1 - 0.43 10.4 10.9 3.9 7.3 0.3 4.4 2 1 2 4 4 4 0 Leucine rich repeat Ank_2 PF12796.7 EGG18326.1 - 0.0061 17.1 0.1 0.26 11.9 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) PGM_PMM_I PF02878.16 EGG18327.1 - 4.4e-37 126.9 0.1 9.5e-37 125.8 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EGG18327.1 - 3.6e-22 78.9 0.0 8.3e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EGG18327.1 - 2.6e-14 53.4 0.0 5.8e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EGG18327.1 - 7.7e-07 29.2 0.0 2.4e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Na_Pi_cotrans PF02690.15 EGG18327.1 - 0.08 13.0 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 Na+/Pi-cotransporter bMG10 PF17973.1 EGG18328.1 - 1.5e-19 70.4 0.2 3.4e-19 69.3 0.2 1.7 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain A2M PF00207.22 EGG18328.1 - 3.4e-14 52.4 0.2 5e-11 42.3 0.0 3.9 3 0 0 3 3 3 1 Alpha-2-macroglobulin family MG2 PF01835.19 EGG18328.1 - 4.9e-06 26.9 0.0 3.3e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 MG2 domain A2M_BRD PF07703.14 EGG18328.1 - 0.00015 22.1 0.2 0.0016 18.8 0.2 2.9 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain DNA_ligase_aden PF01653.18 EGG18329.1 - 1.3e-61 208.4 4.2 7.9e-61 205.9 4.2 2.1 1 1 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 EGG18329.1 - 2.5e-27 94.6 1.2 7.1e-27 93.1 1.2 1.8 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 EGG18329.1 - 1.3e-13 50.8 0.0 5.5e-13 48.8 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif BRCT PF00533.26 EGG18329.1 - 1.2e-12 48.0 0.3 4.2e-12 46.3 0.3 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.6 EGG18329.1 - 8.5e-09 35.9 0.2 7.4e-05 23.3 0.1 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain Ras PF00071.22 EGG18332.1 - 4.9e-17 62.0 0.1 2.2e-16 59.9 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG18332.1 - 9.5e-08 32.3 0.7 1.1e-06 28.8 0.1 2.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 EGG18332.1 - 0.00041 20.9 0.1 0.0024 18.4 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) eRF1_1 PF03463.15 EGG18334.1 - 5.4e-45 152.5 3.5 1.1e-44 151.5 3.5 1.6 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 EGG18334.1 - 1.6e-26 93.2 0.1 3e-26 92.3 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGG18334.1 - 5.6e-24 84.8 0.0 1.3e-23 83.6 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 Arteri_GP4 PF02497.15 EGG18334.1 - 0.046 13.8 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Arterivirus glycoprotein LAGLIDADG_1 PF00961.19 EGG18335.1 - 1.1 10.3 6.1 3.8 8.5 0.0 3.1 3 0 0 3 3 3 0 LAGLIDADG endonuclease ILEI PF15711.5 EGG18336.1 - 8.8e-12 45.4 0.0 1.8e-11 44.3 0.0 1.5 2 0 0 2 2 2 1 Interleukin-like EMT inducer DUF1604 PF07713.13 EGG18338.1 - 1.1e-36 124.5 3.3 1.1e-36 124.5 3.3 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EGG18338.1 - 0.00014 21.6 0.2 0.00039 20.3 0.2 1.8 1 0 0 1 1 1 1 G-patch domain SR-25 PF10500.9 EGG18338.1 - 0.00085 19.0 31.8 0.00085 19.0 31.8 4.2 5 1 0 5 5 5 1 Nuclear RNA-splicing-associated protein UPF0730 PF15827.5 EGG18338.1 - 0.082 12.6 0.0 0.35 10.6 0.0 2.0 1 0 0 1 1 1 0 UPF0730 unknown protein family G-patch_2 PF12656.7 EGG18338.1 - 0.1 12.7 0.0 0.1 12.7 0.0 5.7 6 1 2 8 8 8 0 G-patch domain Mucin PF01456.17 EGG18338.1 - 0.31 11.0 17.0 2.2 8.2 7.6 2.8 2 0 0 2 2 2 0 Mucin-like glycoprotein MCM PF00493.23 EGG18339.1 - 2.1e-88 295.2 0.0 3.4e-88 294.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EGG18339.1 - 3e-26 91.6 1.0 1.3e-25 89.7 1.0 2.2 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 EGG18339.1 - 5e-25 87.8 0.4 8.3e-25 87.1 0.4 1.3 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 EGG18339.1 - 7.1e-10 38.6 0.0 5.1e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGG18339.1 - 1e-06 28.8 0.0 2.8e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGG18339.1 - 5.7e-06 26.2 0.0 3e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG18339.1 - 0.0012 19.3 0.4 0.0054 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 EGG18339.1 - 0.016 14.9 0.0 0.079 12.7 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Lon_2 PF13337.6 EGG18339.1 - 0.028 13.0 0.0 0.053 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease AAA PF00004.29 EGG18339.1 - 0.072 13.5 0.0 1.4 9.3 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EGG18339.1 - 0.082 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein tRNA_anti-codon PF01336.25 EGG18339.1 - 0.13 12.3 0.9 0.8 9.7 0.0 2.6 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain AAA_lid_2 PF17863.1 EGG18339.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA lid domain Pkinase_Tyr PF07714.17 EGG18340.1 - 4.4e-46 157.2 0.1 6.2e-46 156.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG18340.1 - 2e-44 151.9 0.1 2.8e-44 151.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 EGG18340.1 - 9.8e-09 35.2 0.5 2.7e-08 33.8 0.1 1.9 2 0 0 2 2 2 1 SH2 domain Kinase-like PF14531.6 EGG18340.1 - 0.0034 16.8 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Cbl_N3 PF02762.14 EGG18340.1 - 0.073 12.9 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain Fes1 PF08609.10 EGG18341.1 - 2.3e-09 38.0 0.3 1.3e-08 35.6 0.1 2.5 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 V-ATPase_H_C PF11698.8 EGG18341.1 - 5.4e-07 29.7 1.3 2.3e-05 24.5 0.1 2.6 3 0 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 EGG18341.1 - 1.5e-05 24.8 0.0 0.019 15.0 0.0 3.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGG18341.1 - 0.0045 17.3 0.0 0.24 11.8 0.0 3.5 3 1 2 5 5 5 1 HEAT repeats DUF465 PF04325.13 EGG18341.1 - 0.12 12.4 2.8 0.38 10.8 2.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF465) LRRFIP PF09738.9 EGG18341.1 - 0.72 9.3 4.5 0.49 9.8 0.7 2.0 2 0 0 2 2 2 0 LRRFIP family Mago-bind PF09282.10 EGG18342.1 - 1e-15 57.2 3.6 2.2e-15 56.2 0.8 2.4 2 0 0 2 2 2 1 Mago binding DUF3439 PF11921.8 EGG18342.1 - 0.3 11.1 11.8 0.67 9.9 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Hamartin PF04388.12 EGG18342.1 - 0.3 9.7 17.2 0.36 9.5 17.2 1.1 1 0 0 1 1 1 0 Hamartin protein Mucin PF01456.17 EGG18342.1 - 0.64 10.0 20.4 0.96 9.4 5.5 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Nop14 PF04147.12 EGG18342.1 - 1.7 6.7 30.1 0.29 9.3 18.9 2.1 2 0 0 2 2 2 0 Nop14-like family tRNA_U5-meth_tr PF05958.11 EGG18343.1 - 1.9e-21 76.5 0.1 3.7e-21 75.5 0.1 1.5 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Ank_2 PF12796.7 EGG18343.1 - 1.1e-13 51.6 4.1 0.00011 22.7 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18343.1 - 1.6e-09 37.8 0.7 0.067 13.5 0.0 6.2 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG18343.1 - 1e-07 32.4 9.2 0.036 14.7 0.1 6.2 6 1 0 6 6 5 3 Ankyrin repeats (many copies) Met_10 PF02475.16 EGG18343.1 - 1.9e-06 27.8 0.1 3.9e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.20 EGG18343.1 - 3.4e-06 26.3 0.0 5.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 EGG18343.1 - 4.5e-06 26.3 0.1 1.2e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ank_3 PF13606.6 EGG18343.1 - 2.1e-05 24.6 0.5 4.2 8.3 0.0 5.4 3 0 0 3 3 3 1 Ankyrin repeat Methyltransf_25 PF13649.6 EGG18343.1 - 0.00034 21.3 0.0 0.0026 18.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.13 EGG18343.1 - 0.0022 17.5 0.0 0.0069 15.9 0.0 1.8 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.20 EGG18343.1 - 0.003 16.9 0.0 0.16 11.3 0.0 2.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EGG18343.1 - 0.0032 17.2 0.2 0.022 14.5 0.0 2.1 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3447 PF11929.8 EGG18343.1 - 0.005 16.8 6.9 4 7.5 0.0 5.3 3 2 2 5 5 5 1 Domain of unknown function (DUF3447) Methyltransf_31 PF13847.6 EGG18343.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGG18343.1 - 0.13 12.1 0.2 0.72 9.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Ank PF00023.30 EGG18343.1 - 4.5 7.9 6.3 70 4.1 0.0 4.6 4 1 1 5 5 4 0 Ankyrin repeat BLOC1_2 PF10046.9 EGG18344.1 - 3.1e-33 113.9 5.9 3.1e-33 113.9 5.9 1.7 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DnaB_C PF03796.15 EGG18344.1 - 0.011 15.0 0.7 0.019 14.3 0.4 1.4 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain KASH_CCD PF14662.6 EGG18344.1 - 0.019 14.8 0.3 0.019 14.8 0.3 2.0 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH SKA1 PF07160.12 EGG18344.1 - 0.065 13.1 10.4 0.08 12.8 5.5 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Stimulus_sens_1 PF13756.6 EGG18344.1 - 0.097 13.3 0.2 0.18 12.4 0.2 1.4 1 0 0 1 1 1 0 Stimulus-sensing domain UPF0449 PF15136.6 EGG18344.1 - 0.22 12.0 6.1 0.31 11.5 0.6 2.6 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Med9 PF07544.13 EGG18344.1 - 0.3 11.2 5.5 0.28 11.3 0.2 3.0 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.12 EGG18344.1 - 0.4 10.7 4.7 0.13 12.3 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4559 PF15112.6 EGG18344.1 - 0.44 10.2 6.9 0.12 12.1 1.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) XhlA PF10779.9 EGG18344.1 - 0.45 10.7 2.9 1.4 9.2 2.9 1.8 1 0 0 1 1 1 0 Haemolysin XhlA HSBP1 PF06825.12 EGG18344.1 - 0.77 9.7 4.6 3.2 7.7 0.2 3.4 3 1 1 4 4 4 0 Heat shock factor binding protein 1 DUF948 PF06103.11 EGG18344.1 - 1.3 9.3 6.5 20 5.5 4.8 3.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Snapin_Pallidin PF14712.6 EGG18344.1 - 1.7 9.1 6.5 0.48 10.9 0.2 2.8 3 1 0 3 3 3 0 Snapin/Pallidin HECT_2 PF09814.9 EGG18344.1 - 2.3 7.0 6.1 0.95 8.2 1.3 1.9 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Prominin PF05478.11 EGG18344.1 - 4.2 5.2 9.7 1.6 6.6 1.4 2.0 1 1 2 3 3 3 0 Prominin PHP PF02811.19 EGG18345.1 - 0.055 13.8 0.2 0.1 12.9 0.2 1.6 1 1 0 1 1 1 0 PHP domain Cys_Met_Meta_PP PF01053.20 EGG18346.1 - 0.047 12.2 1.0 0.069 11.7 1.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PhosphMutase PF10143.9 EGG18347.1 - 8.3e-55 185.2 0.0 1.3e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 EGG18347.1 - 1.7e-24 86.6 0.0 2.2e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Ribosomal_L12 PF00542.19 EGG18347.1 - 0.061 13.7 0.5 0.15 12.4 0.5 1.6 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain Oxysterol_BP PF01237.18 EGG18348.1 - 4.2e-58 197.0 6.0 7.8e-56 189.5 6.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein HTH_40 PF14493.6 EGG18348.1 - 0.089 13.3 0.2 3.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain PIP5K PF01504.18 EGG18349.1 - 2.4e-23 82.7 40.1 4e-11 42.6 9.8 4.2 3 2 1 4 4 4 3 Phosphatidylinositol-4-phosphate 5-Kinase Ank_5 PF13857.6 EGG18351.1 - 1.9e-25 88.6 1.4 0.0019 18.4 0.0 8.1 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18351.1 - 4.5e-25 88.1 3.0 3.3e-07 30.8 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18351.1 - 2.3e-21 75.9 5.0 0.00016 22.1 0.1 6.3 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18351.1 - 5.7e-16 57.0 5.1 0.25 12.0 0.0 8.3 8 1 1 9 9 9 4 Ankyrin repeat DUF5049 PF16468.5 EGG18351.1 - 3.3e-09 36.5 5.3 0.49 10.3 0.0 6.0 2 2 4 6 6 6 3 Domain of unknown function (DUF5049) DUF249 PF03158.13 EGG18351.1 - 0.00052 19.8 1.2 0.26 11.0 0.2 2.7 1 1 1 2 2 2 2 Multigene family 530 protein Ank PF00023.30 EGG18351.1 - 0.00056 20.2 0.1 70 4.1 0.0 5.7 3 1 2 5 5 5 0 Ankyrin repeat Ndc80_HEC PF03801.13 EGG18351.1 - 0.023 14.4 0.1 0.29 10.7 0.1 2.7 2 1 2 4 4 4 0 HEC/Ndc80p family VWA_3_C PF18571.1 EGG18351.1 - 0.16 11.9 0.1 1.8 8.5 0.0 2.8 3 1 0 3 3 3 0 von Willebrand factor type A C-terminal domain Methyltr_RsmB-F PF01189.17 EGG18352.1 - 1.1e-22 80.7 2.2 2.1e-15 56.9 0.0 3.0 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EGG18352.1 - 0.0023 18.1 0.2 0.0085 16.2 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Enoyl_reductase PF12241.8 EGG18352.1 - 0.094 12.0 0.1 0.37 10.1 0.0 2.0 2 1 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region zf-CDGSH PF09360.10 EGG18354.1 - 2.7e-22 78.7 3.9 3e-11 43.4 0.2 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type MSL2-CXC PF16682.5 EGG18354.1 - 0.085 13.0 5.5 0.38 10.9 0.2 2.5 2 1 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 LRR_4 PF12799.7 EGG18355.1 - 0.0022 18.4 36.6 0.024 15.0 1.5 8.4 6 3 4 10 10 10 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG18355.1 - 2.1 8.1 18.6 7.2 6.5 0.6 5.8 5 1 0 5 5 5 0 Leucine rich repeat Pkinase_Tyr PF07714.17 EGG18356.1 - 2.6e-49 167.9 0.0 3.6e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG18356.1 - 5.1e-45 153.9 0.0 8e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 EGG18356.1 - 2.8e-30 105.6 0.0 9.6e-27 94.1 0.0 2.3 2 0 0 2 2 2 2 C-terminal of Roc, COR, domain Roc PF08477.13 EGG18356.1 - 4.6e-21 75.3 0.6 1.6e-15 57.4 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG18356.1 - 1.3e-08 34.6 0.0 9.9e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 Ras family Gtr1_RagA PF04670.12 EGG18356.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG18356.1 - 0.0063 16.6 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Kdo PF06293.14 EGG18356.1 - 0.037 13.4 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGEF PF00621.20 EGG18357.1 - 4.2e-14 53.2 4.9 5.2e-10 39.9 3.8 3.3 4 0 0 4 4 4 2 RhoGEF domain LRR_6 PF13516.6 EGG18357.1 - 3.2e-05 23.6 1.1 0.45 10.7 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeat PH_13 PF16652.5 EGG18357.1 - 0.00035 20.4 0.4 0.00035 20.4 0.4 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EGG18357.1 - 0.00041 20.8 0.3 0.0015 19.0 0.3 2.0 1 0 0 1 1 1 1 PH domain DNA_repr_REX1B PF14966.6 EGG18357.1 - 0.035 14.8 1.0 0.21 12.3 0.1 2.6 2 0 0 2 2 2 0 DNA repair REX1-B PseudoU_synth_2 PF00849.22 EGG18358.1 - 1.3e-14 54.6 0.1 1.6e-14 54.3 0.1 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase OrfB_Zn_ribbon PF07282.11 EGG18359.1 - 9.9e-06 25.4 0.0 0.0064 16.4 0.0 3.1 2 0 0 2 2 2 2 Putative transposase DNA-binding domain DUF2992 PF11208.8 EGG18359.1 - 0.57 10.4 0.0 0.57 10.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Rho_N PF07498.12 EGG18359.1 - 0.85 9.6 2.3 5.2 7.1 0.2 2.9 3 0 0 3 3 3 0 Rho termination factor, N-terminal domain RICTOR_phospho PF14665.6 EGG18361.1 - 0.02 15.2 1.2 0.11 12.8 0.1 2.3 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site DUF3439 PF11921.8 EGG18361.1 - 0.033 14.2 0.5 0.048 13.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-RING_2 PF13639.6 EGG18363.1 - 4.8e-09 36.4 8.3 4.8e-09 36.4 8.3 1.7 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 EGG18363.1 - 9.3e-08 32.2 4.9 3.7e-07 30.3 4.9 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EGG18363.1 - 1.2e-06 28.3 4.7 1.2e-06 28.3 4.7 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG18363.1 - 1.4e-06 28.2 4.3 1.7e-06 27.9 2.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG18363.1 - 2.5e-06 27.2 6.6 5.8e-06 26.1 6.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG18363.1 - 5.7e-06 26.1 5.5 1.2e-05 25.0 5.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGG18363.1 - 4.1e-05 23.3 7.4 4.1e-05 23.3 7.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG18363.1 - 5.2e-05 23.1 4.0 0.00013 21.9 4.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EGG18363.1 - 0.001 18.6 4.2 0.001 18.6 4.2 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EGG18363.1 - 0.0074 16.4 2.2 0.024 14.8 2.2 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGG18363.1 - 0.0091 16.0 3.0 0.029 14.4 3.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 EGG18363.1 - 0.37 11.1 6.0 0.75 10.1 6.0 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EGG18363.1 - 3.3 7.6 4.6 17 5.3 4.8 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PRP38_assoc PF12871.7 EGG18363.1 - 3.4 8.4 18.2 0.47 11.1 13.5 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-RING_11 PF17123.5 EGG18363.1 - 4.6 7.1 9.6 0.26 11.1 4.0 1.9 2 0 0 2 2 2 0 RING-like zinc finger RINGv PF12906.7 EGG18363.1 - 9.3 6.5 11.4 2.3 8.4 7.5 2.0 2 0 0 2 2 2 0 RING-variant domain DUF2054 PF10218.9 EGG18364.1 - 1.6e-33 115.6 22.1 4.3e-33 114.2 22.1 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) DHHA1 PF02272.19 EGG18364.1 - 1e-07 32.5 0.0 3.7e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.20 EGG18364.1 - 0.00015 22.0 7.3 0.00062 20.0 3.6 3.1 2 1 0 2 2 2 1 DHH family Complex1_LYR PF05347.15 EGG18365.1 - 0.002 18.2 1.5 0.0021 18.1 0.1 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) AMMECR1 PF01871.17 EGG18367.1 - 1.9e-48 164.3 0.0 2.2e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 BDHCT PF08072.11 EGG18367.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 BDHCT (NUC031) domain TFIIA_gamma_C PF02751.14 EGG18368.1 - 1.7e-23 82.4 0.7 2.6e-23 81.9 0.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 EGG18368.1 - 1.4e-21 76.2 0.5 1.9e-21 75.8 0.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain DHR-2 PF06920.13 EGG18369.1 - 3.4e-109 365.9 2.9 3.4e-109 365.9 2.9 1.7 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 EGG18369.1 - 2.4e-29 102.6 3.9 5e-28 98.2 1.9 3.0 2 1 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 EGG18369.1 - 3e-14 52.8 0.3 9.3e-14 51.1 0.3 1.8 1 0 0 1 1 1 1 DOCK N-terminus C2 PF00168.30 EGG18369.1 - 3.2e-05 24.1 0.3 0.0001 22.6 0.0 2.0 2 0 0 2 2 2 1 C2 domain SH3_2 PF07653.17 EGG18369.1 - 0.0023 17.6 0.3 3.7 7.3 0.0 2.8 2 1 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EGG18369.1 - 0.023 14.3 0.1 9.4 5.9 0.1 2.6 2 0 0 2 2 2 0 SH3 domain WH1 PF00568.23 EGG18370.1 - 3.9e-23 81.5 0.1 5.7e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 EGG18370.1 - 5.3e-19 68.3 0.1 1.1e-18 67.3 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain DCP1 PF06058.13 EGG18370.1 - 1e-05 25.4 0.1 1.5e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family WH2 PF02205.20 EGG18370.1 - 5.8e-05 22.8 0.1 5.8e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 WH2 motif RCC1 PF00415.18 EGG18371.1 - 1.1e-36 125.2 1.3 9.4e-11 42.2 0.0 6.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG18371.1 - 1.5e-27 94.8 11.4 1.1e-08 34.6 1.7 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Myb_DNA-binding PF00249.31 EGG18371.1 - 2e-20 72.7 0.5 1.4e-06 28.4 0.0 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG18371.1 - 3.2e-12 46.5 1.3 0.0014 18.8 0.0 4.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain YL1 PF05764.13 EGG18371.1 - 1.6 8.8 73.0 0.15 12.2 7.2 5.7 5 0 0 5 5 5 0 YL1 nuclear protein AA_permease_2 PF13520.6 EGG18372.1 - 6.5e-46 157.0 45.7 6.5e-46 157.0 45.7 1.5 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 EGG18372.1 - 1.7e-41 142.3 38.4 2.6e-41 141.7 38.4 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 EGG18372.1 - 2.5e-18 65.9 2.8 2.5e-18 65.9 2.8 4.7 7 0 0 7 7 7 1 C-terminus of AA_permease Spore_permease PF03845.13 EGG18372.1 - 0.00015 20.7 15.6 0.00015 20.7 15.6 3.1 3 1 0 3 3 3 1 Spore germination protein DUF2523 PF10734.9 EGG18372.1 - 0.023 15.3 4.3 0.93 10.1 0.1 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2523) DUF4535 PF15054.6 EGG18373.1 - 4.7e-16 58.2 0.0 5.1e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4535) ACOX PF01756.19 EGG18374.1 - 3.3e-46 157.1 0.0 7.9e-46 155.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EGG18374.1 - 2.3e-17 63.7 0.0 4.7e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EGG18374.1 - 2.3e-11 43.7 0.0 4.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGG18374.1 - 0.0028 17.9 0.0 0.0071 16.6 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGG18374.1 - 0.19 12.4 0.0 0.9 10.2 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Ras PF00071.22 EGG18375.1 - 7.7e-58 194.7 0.0 9.6e-58 194.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG18375.1 - 3.5e-21 75.6 0.0 8.6e-21 74.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG18375.1 - 1.1e-08 34.8 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG18375.1 - 1.2e-05 24.9 0.0 1.9e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGG18375.1 - 0.00041 20.3 0.0 0.57 10.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Syntaxin-18_N PF10496.9 EGG18375.1 - 0.024 14.9 1.8 0.054 13.7 1.8 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus AAA_25 PF13481.6 EGG18375.1 - 0.041 13.5 0.0 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGG18375.1 - 0.061 13.4 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG18375.1 - 0.14 11.7 0.0 0.38 10.3 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B WD40 PF00400.32 EGG18376.1 - 1.9e-17 63.3 4.5 0.00011 22.9 0.5 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG18376.1 - 1.1e-05 25.7 0.1 0.13 12.5 0.0 4.0 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Tox-MPTase2 PF15638.6 EGG18376.1 - 0.01 15.6 0.8 0.025 14.3 0.8 1.6 1 0 0 1 1 1 0 Metallopeptidase toxin 2 HSP90 PF00183.18 EGG18377.1 - 2e-225 749.6 31.3 2.7e-225 749.2 31.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGG18377.1 - 3.1e-14 53.4 0.1 7e-14 52.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGG18377.1 - 2.6e-07 30.6 0.1 2.6e-07 30.6 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FadR_C PF07840.12 EGG18377.1 - 0.011 15.7 1.2 4.4 7.2 0.0 3.0 2 0 0 2 2 2 0 FadR C-terminal domain LRR_6 PF13516.6 EGG18378.1 - 1.5e-09 37.1 48.0 0.055 13.5 1.8 12.3 14 0 0 14 14 14 8 Leucine Rich repeat Peptidase_C71 PF12386.8 EGG18379.1 - 0.066 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei CSD PF00313.22 EGG18381.1 - 0.029 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Ank_2 PF12796.7 EGG18382.1 - 3.1e-34 117.4 28.7 4.6e-08 33.5 0.3 6.8 1 1 9 10 10 10 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18382.1 - 1.2e-26 92.4 8.9 0.0016 18.7 0.0 11.8 4 3 8 12 12 12 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG18382.1 - 5.9e-26 90.5 9.3 4.6e-06 27.1 0.0 8.9 5 3 4 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18382.1 - 1.1e-13 49.9 8.3 4.3 8.2 0.0 11.8 11 2 2 13 13 13 1 Ankyrin repeat Ank PF00023.30 EGG18382.1 - 2.8e-05 24.3 3.3 22 5.7 0.0 8.3 6 3 2 8 8 8 0 Ankyrin repeat DUF5049 PF16468.5 EGG18382.1 - 0.00024 20.9 0.9 40 4.2 0.0 5.9 5 2 2 7 7 7 0 Domain of unknown function (DUF5049) DUF1619 PF07773.11 EGG18382.1 - 0.009 16.0 1.0 0.009 16.0 1.0 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF1619) DUF2790 PF10976.8 EGG18382.1 - 0.035 14.1 0.2 0.62 10.1 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2790) IBR PF01485.21 EGG18384.1 - 1.3e-06 28.5 34.3 0.00038 20.6 2.3 4.2 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 EGG18384.1 - 0.00046 20.1 8.2 0.00046 20.1 8.2 3.8 3 1 0 3 3 3 2 zinc-RING finger domain zf-RING_2 PF13639.6 EGG18384.1 - 0.00063 20.0 7.7 0.00063 20.0 7.7 4.0 3 2 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 EGG18384.1 - 0.0019 18.0 13.8 0.0044 16.9 6.8 3.8 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGG18384.1 - 0.023 14.5 9.6 0.023 14.5 9.6 4.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG18384.1 - 0.72 9.9 27.3 0.34 11.0 6.2 3.7 3 1 0 3 3 3 0 RING-type zinc-finger zf-B_box PF00643.24 EGG18384.1 - 5.3 7.3 27.3 4.1 7.6 9.7 4.2 3 1 0 3 3 3 0 B-box zinc finger FYVE_2 PF02318.16 EGG18384.1 - 6.8 6.9 30.1 0.95 9.7 8.5 3.4 1 1 2 3 3 3 0 FYVE-type zinc finger NmrA PF05368.13 EGG18385.1 - 2.2e-26 92.9 0.0 3.6e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DUF2487 PF10673.9 EGG18385.1 - 0.00029 20.9 0.0 0.0069 16.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) NAD_binding_10 PF13460.6 EGG18385.1 - 0.005 16.8 0.0 0.0075 16.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DUF836 PF05768.14 EGG18385.1 - 0.1 13.0 0.1 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) 3Beta_HSD PF01073.19 EGG18385.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SnoaL_2 PF12680.7 EGG18386.1 - 0.0018 18.9 0.0 0.0023 18.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain ArsA_ATPase PF02374.15 EGG18386.1 - 0.097 11.8 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase CENP-B_dimeris PF09026.10 EGG18387.1 - 0.059 13.8 2.5 0.058 13.8 2.5 1.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NmrA PF05368.13 EGG18388.1 - 1.5e-29 103.2 0.1 2.1e-29 102.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGG18388.1 - 2e-08 34.3 0.0 4.8e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGG18388.1 - 0.021 13.8 0.1 0.032 13.2 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_L2_C PF03947.18 EGG18390.1 - 7.7e-46 155.4 5.2 1.7e-45 154.3 5.2 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGG18390.1 - 3.3e-17 62.2 0.0 1.5e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain PARP PF00644.20 EGG18391.1 - 6.7e-68 228.1 0.0 6.7e-68 228.1 0.0 2.1 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGG18391.1 - 1.2e-42 145.2 2.3 2.7e-42 144.1 2.3 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EGG18391.1 - 8.8e-16 57.7 0.7 2.2e-15 56.5 0.7 1.7 1 0 0 1 1 1 1 WGR domain PADR1 PF08063.12 EGG18391.1 - 1.7e-15 56.5 1.3 1.7e-15 56.5 1.3 1.9 2 0 0 2 2 2 1 PADR1 (NUC008) domain zf-PARP PF00645.18 EGG18391.1 - 3.1e-12 47.2 0.3 1.5e-11 45.0 0.3 2.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region BRCT_2 PF16589.5 EGG18391.1 - 0.00012 22.4 1.5 0.0037 17.6 0.1 3.7 4 1 0 4 4 4 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG18391.1 - 0.00022 21.5 0.0 0.003 17.9 0.0 2.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain CDC45 PF02724.14 EGG18391.1 - 0.062 11.6 5.7 0.094 11.0 5.7 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF676 PF05057.14 EGG18392.1 - 1.4e-36 126.1 0.3 3.2e-36 124.9 0.3 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) VHP PF02209.19 EGG18392.1 - 1.4e-14 53.8 0.7 5.5e-14 51.9 0.7 2.1 1 0 0 1 1 1 1 Villin headpiece domain DUF3657 PF12394.8 EGG18392.1 - 6e-11 42.7 0.0 6e-11 42.7 0.0 3.6 3 0 0 3 3 3 1 Protein FAM135 PGAP1 PF07819.13 EGG18392.1 - 5.4e-05 23.0 0.3 0.00024 20.9 0.3 2.0 1 1 0 1 1 1 1 PGAP1-like protein MIP PF00230.20 EGG18393.1 - 6.6e-47 160.1 23.2 1.3e-45 155.9 23.2 2.0 1 1 0 1 1 1 1 Major intrinsic protein DUF2721 PF11026.8 EGG18393.1 - 0.016 15.1 0.0 0.016 15.1 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) Oxidored_q3 PF00499.20 EGG18393.1 - 4.7 6.9 10.8 21 4.8 8.1 2.7 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 CLTH PF10607.9 EGG18394.1 - 2.5e-35 121.5 3.0 3.8e-35 120.9 3.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGG18394.1 - 6.4e-10 38.6 3.4 6.7e-10 38.6 0.6 2.4 3 0 0 3 3 3 1 LisH Usg PF06233.12 EGG18394.1 - 0.076 13.2 0.0 0.38 10.9 0.0 2.2 3 0 0 3 3 3 0 Usg-like family Syntaxin-6_N PF09177.11 EGG18394.1 - 0.13 12.9 3.1 0.32 11.6 0.4 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4434 PF14488.6 EGG18394.1 - 0.34 10.9 2.5 0.28 11.2 0.3 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4434) EF-hand_1 PF00036.32 EGG18396.1 - 7.5e-19 65.8 0.5 3.3e-05 23.1 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGG18396.1 - 3.6e-17 62.6 0.2 2.5e-10 40.7 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGG18396.1 - 6.2e-17 60.0 1.2 4.4e-05 23.1 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EGG18396.1 - 5.5e-13 48.5 3.8 1.4e-05 24.8 0.2 3.4 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGG18396.1 - 7.8e-13 47.3 1.0 0.00029 20.2 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 EGG18396.1 - 4.6e-05 23.7 0.1 0.007 16.7 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 EGG18396.1 - 0.00028 20.8 0.0 0.0034 17.3 0.0 2.4 1 1 2 3 3 3 1 Caleosin related protein Dockerin_1 PF00404.18 EGG18396.1 - 0.46 10.7 4.2 0.68 10.2 0.6 2.7 2 2 1 3 3 3 0 Dockerin type I domain Mog1 PF04603.12 EGG18397.1 - 4.1e-42 143.8 0.2 5.3e-42 143.5 0.2 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein zf-C3HC4_3 PF13920.6 EGG18398.1 - 2.5e-09 36.8 15.4 4e-09 36.2 15.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG18398.1 - 6.2e-07 29.2 17.9 1e-06 28.4 17.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG18398.1 - 1.9e-05 24.4 14.2 5.9e-05 22.8 14.4 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGG18398.1 - 0.00011 22.4 18.1 0.00019 21.7 18.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGG18398.1 - 0.00028 20.7 18.6 0.00058 19.7 18.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FdhE PF04216.12 EGG18398.1 - 0.0015 18.5 7.7 0.0015 18.5 7.7 1.6 1 1 0 1 1 1 1 Protein involved in formate dehydrogenase formation zf-RING_5 PF14634.6 EGG18398.1 - 0.0021 18.0 15.3 0.0098 15.8 15.7 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGG18398.1 - 0.0097 16.2 12.6 0.022 15.0 12.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EGG18398.1 - 0.79 9.9 11.9 1.6 8.9 11.9 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 EGG18398.1 - 4.1 7.5 14.7 3.6 7.7 12.6 2.0 1 1 1 2 2 2 0 RING-type zinc-finger Ribosomal_L22 PF00237.19 EGG18399.1 - 3.8e-32 110.6 0.1 5.2e-32 110.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF5024 PF16427.5 EGG18400.1 - 0.022 15.1 0.1 0.16 12.3 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5024) Peptidase_M99_C PF17129.4 EGG18400.1 - 0.041 14.1 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of metallo-carboxypeptidase RhoGEF PF00621.20 EGG18402.1 - 6.9e-43 147.0 0.2 5.9e-38 130.9 0.0 2.7 2 0 0 2 2 2 2 RhoGEF domain PH_16 PF17838.1 EGG18402.1 - 0.0017 18.2 0.1 0.0048 16.7 0.1 1.8 1 0 0 1 1 1 1 PH domain DUF4131 PF13567.6 EGG18404.1 - 0.14 11.7 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PKD_channel PF08016.12 EGG18405.1 - 1.8e-07 30.2 6.2 1.8e-07 30.2 6.2 1.8 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 EGG18405.1 - 0.0012 18.2 15.5 0.0012 18.2 15.5 2.7 2 1 0 2 2 2 1 Ion transport protein AATF-Che1 PF13339.6 EGG18405.1 - 0.5 11.1 6.6 0.61 10.8 4.0 2.4 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor Zn_peptidase_2 PF04298.12 EGG18406.1 - 0.016 14.6 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase UQ_con PF00179.26 EGG18408.1 - 2.2e-49 166.7 0.1 2.4e-49 166.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGG18408.1 - 6.4e-05 22.7 0.0 0.00012 21.7 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGG18408.1 - 0.014 15.7 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain Calsarcin PF05556.11 EGG18408.1 - 0.075 12.6 0.1 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-binding protein (Calsarcin) UEV PF05743.13 EGG18408.1 - 0.078 12.8 0.2 0.12 12.2 0.2 1.5 1 1 0 1 1 1 0 UEV domain HTH_AraC PF00165.23 EGG18408.1 - 0.11 12.6 0.3 2.1 8.6 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family CLN5 PF15014.6 EGG18409.1 - 8.5e-18 65.1 6.5 1.4e-17 64.4 6.5 1.2 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 ATG27 PF09451.10 EGG18409.1 - 6e-14 52.5 0.0 1.2e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 EGG18409.1 - 3.6e-07 29.6 0.1 5.8e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor DUF2430 PF10353.9 EGG18409.1 - 0.031 14.7 1.3 9.5 6.7 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2430) Rav1p_C PF12234.8 EGG18410.1 - 1.7e-88 297.6 20.3 1e-74 252.2 3.6 4.9 3 2 1 5 5 5 2 RAVE protein 1 C terminal WD40 PF00400.32 EGG18410.1 - 9.9e-15 54.7 41.4 0.034 15.0 0.0 12.4 13 0 0 13 13 13 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG18410.1 - 6e-05 23.3 0.4 0.08 13.2 0.0 5.1 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Oxysterol_BP PF01237.18 EGG18411.1 - 2e-59 201.3 5.0 2.9e-59 200.8 5.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein TaqI_C PF12950.7 EGG18411.1 - 0.012 15.6 0.5 0.032 14.3 0.5 1.7 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Peptidase_M41 PF01434.18 EGG18412.1 - 3.8e-66 222.6 0.3 8.3e-66 221.5 0.3 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGG18412.1 - 8.1e-43 146.0 0.0 3e-42 144.2 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG18412.1 - 8.4e-13 47.9 0.1 2.2e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGG18412.1 - 3.4e-05 23.8 0.1 0.00023 21.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) BUD22 PF09073.10 EGG18412.1 - 5.8e-05 22.6 17.5 5.8e-05 22.6 17.5 1.5 2 0 0 2 2 2 1 BUD22 AAA_22 PF13401.6 EGG18412.1 - 0.00075 19.8 0.6 0.37 11.1 0.1 3.1 3 0 0 3 3 2 1 AAA domain FtsH_ext PF06480.15 EGG18412.1 - 0.001 19.4 1.1 0.005 17.2 0.1 2.7 3 0 0 3 3 2 1 FtsH Extracellular Serinc PF03348.15 EGG18412.1 - 0.0029 16.6 3.2 0.0054 15.7 3.2 1.4 1 0 0 1 1 1 1 Serine incorporator (Serinc) DDHD PF02862.17 EGG18412.1 - 0.004 17.4 8.4 0.004 17.4 8.4 2.0 2 0 0 2 2 2 1 DDHD domain AAA_33 PF13671.6 EGG18412.1 - 0.0045 17.2 0.1 0.02 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGG18412.1 - 0.0053 17.2 0.2 0.38 11.1 0.1 3.2 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EGG18412.1 - 0.0093 15.7 0.1 0.032 14.0 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGG18412.1 - 0.019 14.7 0.2 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGG18412.1 - 0.094 12.1 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CDC45 PF02724.14 EGG18412.1 - 0.14 10.4 18.0 0.22 9.7 18.0 1.3 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.16 EGG18412.1 - 0.29 10.5 23.2 0.59 9.4 23.2 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4337 PF14235.6 EGG18412.1 - 0.31 11.1 7.1 1 9.4 7.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Macoilin PF09726.9 EGG18412.1 - 0.51 8.8 18.2 0.85 8.1 18.2 1.3 1 0 0 1 1 1 0 Macoilin family PBP_sp32 PF07222.12 EGG18412.1 - 0.66 9.4 11.9 1.6 8.1 11.9 1.7 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CCDC71L PF15374.6 EGG18412.1 - 0.98 8.6 16.4 1.7 7.8 16.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L DUF1682 PF07946.14 EGG18412.1 - 1.2 8.3 20.4 2.2 7.4 20.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ALMT PF11744.8 EGG18412.1 - 1.4 7.7 24.3 2.6 6.8 24.3 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 EGG18412.1 - 1.4 8.9 8.9 3.7 7.5 8.9 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.16 EGG18412.1 - 1.8 7.4 13.2 3.8 6.3 13.2 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein PRK PF00485.18 EGG18413.1 - 7.8e-25 87.8 0.7 4.3e-24 85.3 0.7 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Acetyltransf_10 PF13673.7 EGG18413.1 - 7.8e-06 25.8 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG18413.1 - 4.7e-05 23.6 0.0 9.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AAA_33 PF13671.6 EGG18413.1 - 0.0009 19.4 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGG18413.1 - 0.0013 18.4 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGG18413.1 - 0.0022 17.2 0.1 0.0044 16.3 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain Acetyltransf_9 PF13527.7 EGG18413.1 - 0.0027 17.8 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG18413.1 - 0.0039 17.6 0.1 0.0091 16.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CbiA PF01656.23 EGG18413.1 - 0.013 15.6 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 EGG18413.1 - 0.03 14.9 0.0 0.092 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGG18413.1 - 0.031 14.2 0.2 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SURNod19 PF07712.12 EGG18413.1 - 0.032 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Stress up-regulated Nod 19 AAA PF00004.29 EGG18413.1 - 0.04 14.3 0.0 0.84 10.1 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EGG18413.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 EGG18413.1 - 0.058 12.7 0.0 0.17 11.1 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EGG18413.1 - 0.079 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EGG18413.1 - 0.1 12.5 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 EGG18413.1 - 0.12 12.3 0.4 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 NTPase NOA36 PF06524.12 EGG18413.1 - 9.1 5.5 15.7 14 4.9 15.7 1.2 1 0 0 1 1 1 0 NOA36 protein CASP_C PF08172.12 EGG18414.1 - 8e-65 218.7 20.6 8e-65 218.7 20.6 4.8 3 1 2 5 5 5 1 CASP C terminal Lebercilin PF15619.6 EGG18414.1 - 0.00048 19.8 18.0 0.00048 19.8 18.0 5.1 1 1 4 5 5 5 1 Ciliary protein causing Leber congenital amaurosis disease CENP-H PF05837.12 EGG18414.1 - 0.021 15.2 1.9 0.021 15.2 1.9 7.0 2 1 4 7 7 7 0 Centromere protein H (CENP-H) Filament PF00038.21 EGG18414.1 - 4.2 6.9 73.2 4.2 6.9 46.1 4.3 2 1 2 4 4 4 0 Intermediate filament protein RasGEF PF00617.19 EGG18415.1 - 2e-36 125.9 0.8 2e-36 125.9 0.8 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGG18415.1 - 9.9e-19 67.5 1.2 1.8e-18 66.7 0.1 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif LisH PF08513.11 EGG18415.1 - 0.0018 18.2 0.0 0.0055 16.6 0.0 1.9 1 0 0 1 1 1 1 LisH LisH_TPL PF17814.1 EGG18415.1 - 0.0098 15.5 1.6 0.024 14.3 0.2 2.6 2 0 0 2 2 2 1 LisH-like dimerisation domain GST_C_3 PF14497.6 EGG18416.1 - 2.1e-21 75.9 0.2 3.8e-21 75.1 0.1 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGG18416.1 - 9.2e-07 29.1 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG18416.1 - 8.5e-06 25.9 0.3 2.1e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG18416.1 - 3.8e-05 23.6 0.0 6.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGG18416.1 - 0.0028 18.0 0.0 0.0089 16.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain HEAT PF02985.22 EGG18417.1 - 3.3e-05 23.8 1.7 11 6.6 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EGG18417.1 - 0.0005 20.1 0.2 0.0005 20.1 0.2 6.1 5 2 3 8 8 8 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGG18417.1 - 0.0027 18.0 0.5 0.17 12.3 0.1 2.8 1 1 2 3 3 3 3 HEAT repeats Cohesin_HEAT PF12765.7 EGG18417.1 - 0.33 11.3 3.4 7.5 7.0 0.1 3.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion STATa_Ig PF18214.1 EGG18419.1 - 9.1e-46 154.8 4.1 1.3e-45 154.3 0.2 2.4 2 0 0 2 2 2 1 STATa Immunoglobulin-like domain EF-hand_12 PF17901.1 EGG18419.1 - 5.9e-43 145.2 1.6 5.9e-43 145.2 1.6 2.3 2 0 0 2 2 2 1 EF-hand fold domain Dict-STAT-coil PF09267.10 EGG18419.1 - 5.6e-42 142.7 13.5 5.6e-42 142.7 13.5 2.3 2 0 0 2 2 2 1 Dictyostelium STAT, coiled coil SH2 PF00017.24 EGG18419.1 - 2.9e-09 36.9 0.0 7.4e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.14 EGG18419.1 - 0.011 15.6 0.0 0.038 13.8 0.0 1.9 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain Dicty_REP PF05086.12 EGG18419.1 - 0.22 9.5 1.1 0.3 9.0 1.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ABC_tran PF00005.27 EGG18420.1 - 1e-28 100.5 0.2 1.4e-27 96.9 0.0 2.6 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 EGG18420.1 - 5.5e-16 58.6 36.2 5.5e-16 58.6 36.2 2.9 3 1 0 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGG18420.1 - 1.4e-10 41.4 0.1 1.7e-05 24.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG18420.1 - 0.00068 19.1 0.0 0.0047 16.4 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 EGG18420.1 - 0.00068 19.1 20.9 0.00068 19.1 20.9 2.5 3 0 0 3 3 3 1 ABC-2 type transporter AAA_23 PF13476.6 EGG18420.1 - 0.1 13.1 0.2 0.1 13.1 0.2 2.5 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 EGG18420.1 - 2 7.6 14.7 5.4 6.2 14.7 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein DPPIV_N PF00930.21 EGG18421.1 - 2.8e-68 230.3 15.0 3.7e-68 229.9 15.0 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EGG18421.1 - 1.8e-48 164.9 0.0 2.9e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGG18421.1 - 6.7e-09 35.7 0.0 1.3e-06 28.3 0.0 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 EGG18421.1 - 3.7e-06 26.8 0.6 0.00018 21.2 0.0 3.1 3 0 0 3 3 3 1 Putative esterase DUF2920 PF11144.8 EGG18421.1 - 0.0047 16.1 0.0 0.013 14.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) Abhydrolase_2 PF02230.16 EGG18421.1 - 0.014 15.2 0.1 0.053 13.3 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EGG18421.1 - 0.028 14.3 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 EGG18421.1 - 0.056 12.1 3.2 0.2 10.3 0.0 2.8 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) DUF3141 PF11339.8 EGG18421.1 - 0.06 11.8 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DLH PF01738.18 EGG18421.1 - 0.076 12.5 0.0 0.53 9.8 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EGG18421.1 - 0.11 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG18421.1 - 0.13 11.5 0.0 0.79 8.9 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AdoHcyase_NAD PF00670.21 EGG18421.1 - 0.17 12.0 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FlgD PF03963.14 EGG18422.1 - 0.016 15.5 1.2 0.022 15.0 1.2 1.4 1 1 0 1 1 1 0 Flagellar hook capping protein - N-terminal region RhoGAP PF00620.27 EGG18423.1 - 3.3e-22 79.0 0.0 1e-21 77.4 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EGG18423.1 - 2.2e-07 31.1 0.8 8.5e-07 29.2 0.6 2.2 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Roughex PF06020.11 EGG18423.1 - 0.21 10.7 9.8 0.35 9.9 9.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF4094 PF13334.6 EGG18423.1 - 0.9 10.0 0.0 0.9 10.0 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) Ank_2 PF12796.7 EGG18424.1 - 1.9e-29 102.1 12.6 8.7e-06 26.2 0.0 6.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18424.1 - 8.5e-29 99.6 13.8 4.8e-06 27.0 0.0 9.7 5 3 5 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18424.1 - 1.1e-26 92.6 10.2 8.9e-05 22.7 0.1 10.5 3 3 8 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18424.1 - 1.7e-21 74.0 11.4 0.11 13.1 0.0 12.6 13 0 0 13 13 12 4 Ankyrin repeat Ank PF00023.30 EGG18424.1 - 5.3e-08 33.0 1.0 7.4 7.2 0.0 8.1 5 3 1 6 6 6 1 Ankyrin repeat DUF5049 PF16468.5 EGG18424.1 - 8e-05 22.5 1.9 30 4.6 0.0 7.4 6 2 3 9 9 9 0 Domain of unknown function (DUF5049) FMO-like PF00743.19 EGG18424.1 - 0.00039 19.0 0.5 0.24 9.8 0.1 3.1 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like AhpC-TSA PF00578.21 EGG18424.1 - 0.00049 20.0 0.4 4.5 7.2 0.0 4.2 3 2 1 4 4 4 1 AhpC/TSA family HIGH_NTase1_ass PF16581.5 EGG18424.1 - 0.049 13.6 0.8 3.6 7.5 0.1 3.5 5 0 0 5 5 5 0 Cytidyltransferase-related C-terminal region SAM_DrpA PF18255.1 EGG18424.1 - 0.14 12.4 0.5 16 5.9 0.0 3.9 4 0 0 4 4 4 0 DNA processing protein A sterile alpha motif domain DUF5454 PF17535.2 EGG18424.1 - 2.3 7.6 6.8 0.58 9.5 1.1 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5454) PIG-L PF02585.17 EGG18425.1 - 4.7e-18 66.1 0.0 1e-17 65.0 0.0 1.6 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glucosamine_iso PF01182.20 EGG18425.1 - 2.1e-16 60.5 0.0 1.9e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SDA1 PF05285.12 EGG18426.1 - 0.28 10.6 25.2 0.29 10.5 25.2 1.0 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EGG18426.1 - 0.45 8.7 19.5 0.49 8.6 19.5 1.0 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 EGG18426.1 - 0.95 8.8 20.7 1.1 8.5 20.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 EGG18426.1 - 2.6 6.2 23.4 2.6 6.1 23.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EGG18426.1 - 4.5 5.3 29.2 6.1 4.8 29.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 EGG18426.1 - 6.4 6.0 22.7 6.3 6.0 22.7 1.0 1 0 0 1 1 1 0 BUD22 Na_trans_assoc PF06512.13 EGG18426.1 - 7.5 6.8 19.7 8.5 6.6 19.7 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2722 PF10846.8 EGG18426.1 - 7.7 5.3 13.5 11 4.9 13.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SWIM PF04434.17 EGG18427.1 - 0.0027 17.3 0.2 0.0057 16.3 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger CobT PF06213.12 EGG18427.1 - 0.021 14.2 18.6 0.021 14.2 18.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.9 EGG18427.1 - 0.068 12.3 32.7 0.085 12.0 32.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 EGG18427.1 - 0.28 9.3 25.7 0.3 9.3 25.7 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EGG18427.1 - 0.31 9.5 23.2 0.34 9.4 23.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Paf1 PF03985.13 EGG18427.1 - 0.37 9.7 18.8 0.46 9.4 18.8 1.1 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.12 EGG18427.1 - 0.42 10.0 25.2 0.45 9.9 25.2 1.1 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 EGG18427.1 - 0.82 10.0 19.2 1.1 9.5 19.2 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CNDH2_C PF16858.5 EGG18427.1 - 0.89 9.4 13.7 0.99 9.2 13.7 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 EGG18427.1 - 1.6 6.9 25.0 1.8 6.7 25.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 EGG18427.1 - 2 7.9 20.0 2.8 7.5 20.0 1.3 1 0 0 1 1 1 0 PPP4R2 CSRNP_N PF16019.5 EGG18427.1 - 2.4 8.0 6.8 4.8 7.0 6.8 1.6 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus TFIIA PF03153.13 EGG18427.1 - 4.2 7.3 25.1 4.8 7.1 25.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 EGG18427.1 - 8.1 5.1 11.9 8.9 5.0 11.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Astro_capsid_p PF12226.8 EGG18427.1 - 8.9 5.4 22.6 12 5.0 22.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein COPI_C PF06957.11 EGG18427.1 - 9.8 4.8 9.3 10 4.7 9.3 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus APH PF01636.23 EGG18428.1 - 4e-18 66.2 0.0 5.5e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGG18428.1 - 0.0045 16.4 0.2 0.042 13.2 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Spt5-NGN PF03439.13 EGG18428.1 - 0.066 13.1 0.0 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section Glyco_hydro_18 PF00704.28 EGG18429.1 - 1.3e-08 34.9 2.3 1.4e-08 34.8 1.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CaKB PF03185.15 EGG18429.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit SR-25 PF10500.9 EGG18430.1 - 0.00023 20.9 20.9 0.00023 20.9 20.9 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 EGG18430.1 - 0.021 15.7 11.5 0.021 15.7 11.5 1.7 2 0 0 2 2 2 0 Chorion family 2 CAF1-p150_C2 PF15539.6 EGG18430.1 - 0.033 13.6 4.8 0.043 13.3 4.8 1.1 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Zip PF02535.22 EGG18430.1 - 0.082 12.1 4.0 0.094 11.9 4.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RAP1 PF07218.11 EGG18430.1 - 0.15 10.3 15.3 0.17 10.1 15.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CCDC106 PF15794.5 EGG18430.1 - 0.86 9.3 18.1 0.027 14.2 12.0 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF1980 PF09323.10 EGG18430.1 - 1.4 8.8 7.7 0.046 13.6 1.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Miga PF10265.9 EGG18430.1 - 1.8 7.4 11.2 2 7.3 11.2 1.1 1 0 0 1 1 1 0 Mitoguardin DUF4834 PF16118.5 EGG18430.1 - 2.8 9.0 11.8 0.29 12.1 5.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) SSP160 PF06933.11 EGG18430.1 - 4.3 5.4 19.2 5.6 5.0 19.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Neur_chan_memb PF02932.16 EGG18430.1 - 8.2 6.4 9.0 5.4 7.0 7.7 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLU PF13236.6 EGG18431.1 - 2.7e-48 164.7 0.0 6.5e-48 163.5 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGG18431.1 - 7.1e-05 22.9 0.0 7.1e-05 22.9 0.0 2.7 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 DUF935 PF06074.12 EGG18431.1 - 0.089 11.5 0.0 0.19 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF935) CBM49 PF09478.10 EGG18432.1 - 1.8e-09 37.8 1.6 2.6e-09 37.2 1.6 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 GST_C_3 PF14497.6 EGG18433.1 - 2.3e-21 75.8 0.2 4.2e-21 75.0 0.1 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGG18433.1 - 1.7e-07 31.5 0.0 3.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG18433.1 - 4.2e-05 23.7 0.2 0.00011 22.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGG18433.1 - 0.00046 20.5 0.0 0.0058 17.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGG18433.1 - 0.00052 20.0 0.0 0.00089 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2264 PF10022.9 EGG18433.1 - 0.094 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Glyco_hydro_14 PF01373.17 EGG18434.1 - 7.5e-117 390.7 7.0 9.4e-117 390.3 7.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 CLASP_N PF12348.8 EGG18435.1 - 1.3e-40 139.4 1.1 2.8e-38 131.8 0.2 2.8 2 0 0 2 2 2 2 CLASP N terminal PIG-P PF08510.12 EGG18436.1 - 8.4e-34 116.1 7.2 2e-33 114.9 7.2 1.7 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EGG18436.1 - 0.023 15.0 10.7 0.047 14.0 10.7 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) HSBP1 PF06825.12 EGG18436.1 - 0.19 11.6 1.1 2.6 8.0 0.1 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Glyco_hydro_92N PF17678.1 EGG18437.1 - 0.0045 16.9 0.1 0.0065 16.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Uma2 PF05685.12 EGG18438.1 - 0.0002 20.9 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 Putative restriction endonuclease Vps53_N PF04100.12 EGG18438.1 - 0.17 10.8 1.9 0.51 9.2 1.0 1.9 2 0 0 2 2 2 0 Vps53-like, N-terminal Imm41 PF15592.6 EGG18439.1 - 0.035 14.4 0.4 0.035 14.4 0.4 3.0 3 0 0 3 3 3 0 Immunity protein 41 Glyco_hydro_92N PF17678.1 EGG18440.1 - 0.035 14.0 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 N-terminal domain DUF4144 PF13642.6 EGG18442.1 - 0.072 13.7 1.9 0.32 11.6 0.1 2.8 3 0 0 3 3 3 0 protein structure with unknown function Folliculin_C PF16692.5 EGG18444.1 - 2.9e-66 223.4 0.2 2.9e-66 223.4 0.2 1.7 2 0 0 2 2 2 1 Folliculin C-terminal domain Folliculin PF11704.8 EGG18444.1 - 1.3e-27 96.8 3.5 1.3e-27 96.8 0.0 2.2 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport RNA_pol_Rpb2_6 PF00562.28 EGG18445.1 - 1.3e-125 419.5 3.5 2.3e-122 408.9 0.8 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGG18445.1 - 2.8e-67 226.2 0.1 6.3e-67 225.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EGG18445.1 - 1.6e-48 164.9 0.0 3.9e-48 163.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EGG18445.1 - 7.9e-36 122.3 0.3 8.8e-35 119.0 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EGG18445.1 - 1e-25 89.7 0.1 2.4e-25 88.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EGG18445.1 - 8e-22 77.3 0.3 2.7e-21 75.6 0.3 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EGG18445.1 - 5.1e-18 65.4 3.4 1.5e-17 63.9 3.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Hint PF01079.20 EGG18445.1 - 9.8e-06 25.2 0.3 3.9e-05 23.3 0.4 2.0 2 0 0 2 2 2 1 Hint module Intein_splicing PF14890.6 EGG18445.1 - 1e-05 25.5 0.0 3.6e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Intein splicing domain Hom_end_hint PF05203.16 EGG18445.1 - 0.0053 16.7 0.2 0.013 15.4 0.2 1.7 1 0 0 1 1 1 1 Hom_end-associated Hint Peptidase_S26 PF10502.9 EGG18445.1 - 0.039 13.7 0.1 0.62 9.8 0.0 2.4 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 PT-HINT PF07591.11 EGG18445.1 - 0.14 12.4 0.1 0.33 11.2 0.1 1.6 1 0 0 1 1 1 0 Pretoxin HINT domain STN1_2 PF09170.10 EGG18445.1 - 1.7 8.8 7.0 0.87 9.8 0.7 3.1 2 1 1 3 3 3 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 SH3_9 PF14604.6 EGG18446.1 - 6.5e-15 54.7 0.1 1.4e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.23 EGG18446.1 - 3.2e-14 53.0 0.4 3.2e-14 53.0 0.4 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EGG18446.1 - 6.3e-13 48.1 0.2 1.2e-12 47.3 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG18446.1 - 2e-12 46.6 0.0 3.8e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain HR1 PF02185.16 EGG18446.1 - 1.7e-06 28.0 3.7 1.7e-06 28.0 3.7 3.0 2 0 0 2 2 2 1 Hr1 repeat GAS PF13851.6 EGG18446.1 - 0.0045 16.4 3.0 0.0045 16.4 3.0 2.5 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF4226 PF10774.9 EGG18446.1 - 0.85 9.9 10.1 0.032 14.5 1.9 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4226) FlaC_arch PF05377.11 EGG18446.1 - 5.4 7.5 8.0 29 5.2 0.5 3.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2951 PF11166.8 EGG18446.1 - 6.3 7.1 12.2 0.71 10.1 4.5 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2951) SR-25 PF10500.9 EGG18447.1 - 0.065 12.8 14.0 0.12 12.0 14.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Miga PF10265.9 EGG18447.1 - 7.1 5.5 11.2 0.16 10.9 4.4 1.5 2 0 0 2 2 2 0 Mitoguardin 2-oxoacid_dh PF00198.23 EGG18449.1 - 7.3e-73 244.9 0.1 7.3e-73 244.9 0.1 1.6 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 EGG18449.1 - 1.1e-11 44.9 0.0 2.9e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain CM_1 PF07736.11 EGG18449.1 - 0.037 14.4 0.4 0.082 13.3 0.4 1.5 1 0 0 1 1 1 0 Chorismate mutase type I COMM_domain PF07258.14 EGG18449.1 - 0.34 11.0 2.0 0.84 9.8 2.0 1.7 1 1 0 1 1 1 0 COMM domain DUF3439 PF11921.8 EGG18449.1 - 0.45 10.5 10.5 0.12 12.3 7.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Joubert PF15392.6 EGG18450.1 - 0.025 14.3 0.5 0.098 12.4 0.0 1.9 2 0 0 2 2 2 0 Joubert syndrome-associated DUF2428 PF10350.9 EGG18451.1 - 1e-80 271.0 0.0 4e-80 269.0 0.0 2.2 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EGG18451.1 - 0.0018 18.4 3.9 0.48 10.8 0.0 6.0 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 EGG18451.1 - 0.088 13.2 0.0 40 4.7 0.0 4.6 5 0 0 5 5 5 0 HEAT repeats HlyIII PF03006.20 EGG18452.1 - 5e-51 173.6 12.7 6.2e-51 173.3 12.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4064 PF13273.6 EGG18452.1 - 0.00075 19.7 0.8 0.054 13.8 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) DUF3452 PF11934.8 EGG18452.1 - 0.0088 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3452) DUF2956 PF11169.8 EGG18452.1 - 0.023 14.9 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Orf78 PF06024.12 EGG18452.1 - 0.18 12.1 1.4 0.3 11.4 0.3 1.9 2 0 0 2 2 2 0 Orf78 (ac78) CrgA PF06781.12 EGG18452.1 - 0.29 11.2 0.0 0.29 11.2 0.0 2.3 3 0 0 3 3 3 0 Cell division protein CrgA DUF1635 PF07795.11 EGG18453.1 - 0.96 9.3 6.5 0.42 10.4 3.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) EphA2_TM PF14575.6 EGG18453.1 - 2.2 9.2 3.9 27 5.8 0.4 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3149 PF11346.8 EGG18453.1 - 3.6 7.3 9.3 7.4 6.3 9.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) SAM_2 PF07647.17 EGG18454.1 - 1.2e-05 25.4 0.0 2.5e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGG18454.1 - 0.024 15.1 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 EGG18454.1 - 0.071 13.4 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Baculo_11_kDa PF06143.11 EGG18454.1 - 0.11 12.1 0.6 0.38 10.4 0.6 1.9 1 0 0 1 1 1 0 Baculovirus 11 kDa family FNIP PF05725.12 EGG18455.1 - 1e-14 54.4 21.3 0.0049 17.0 0.0 9.6 6 3 3 10 10 10 6 FNIP Repeat F-box-like PF12937.7 EGG18456.1 - 0.0013 18.5 0.2 0.0061 16.4 0.0 2.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EGG18456.1 - 0.029 14.2 0.0 0.074 13.0 0.0 1.8 1 1 0 1 1 1 0 F-box domain F-box_5 PF18511.1 EGG18456.1 - 0.1 12.2 0.4 0.24 11.0 0.4 1.6 1 0 0 1 1 1 0 F-box dUTPase PF00692.19 EGG18457.1 - 2.1e-13 50.1 0.1 5.1e-13 48.8 0.0 1.7 2 0 0 2 2 2 1 dUTPase LAGLIDADG_3 PF14528.6 EGG18457.1 - 0.048 14.0 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 LAGLIDADG-like domain MKT1_C PF12246.8 EGG18458.1 - 6.1e-49 166.4 1.7 8e-49 166.1 0.3 2.0 2 1 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EGG18458.1 - 5.1e-21 74.8 0.0 1.6e-20 73.2 0.0 2.0 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 EGG18458.1 - 2.6e-05 24.6 0.0 0.00081 19.8 0.0 2.7 2 0 0 2 2 2 1 XPG N-terminal domain DUF4769 PF15992.5 EGG18458.1 - 0.13 12.1 0.2 0.85 9.4 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4769) DUF2012 PF09430.10 EGG18459.1 - 1e-18 67.7 0.3 3e-18 66.1 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) JAB PF01398.21 EGG18459.1 - 4.7e-11 42.7 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CarbopepD_reg_2 PF13715.6 EGG18459.1 - 0.027 14.4 0.0 0.08 12.9 0.0 1.8 1 0 0 1 1 1 0 CarboxypepD_reg-like domain SdrD_B PF17210.3 EGG18459.1 - 0.044 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 SdrD B-like domain PH PF00169.29 EGG18460.1 - 5.8e-27 94.3 3.7 1.3e-12 48.1 0.3 2.7 2 0 0 2 2 2 2 PH domain Yop-YscD_cpl PF16697.5 EGG18460.1 - 4.8e-16 58.9 0.1 1.3e-15 57.4 0.1 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 EGG18460.1 - 8.5e-16 58.1 2.1 2e-15 56.9 2.1 1.7 1 0 0 1 1 1 1 FHA domain PH_8 PF15409.6 EGG18460.1 - 5.9e-07 29.7 2.3 0.021 15.1 0.9 3.5 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 EGG18460.1 - 2.8e-05 24.5 16.3 0.017 15.6 2.1 4.4 3 2 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 EGG18460.1 - 0.0011 19.4 4.8 4.1 7.8 0.3 4.5 3 2 0 3 3 3 2 Pleckstrin homology domain DUF3963 PF13124.6 EGG18461.1 - 0.0053 16.7 0.1 0.0071 16.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3963) Glutaredoxin PF00462.24 EGG18462.1 - 5.4e-19 68.2 0.0 4.8e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EGG18462.1 - 1.2e-15 57.4 1.5 1.4e-15 57.1 0.3 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 EGG18462.1 - 0.00015 22.0 1.4 0.00036 20.8 0.1 2.3 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGG18462.1 - 0.0011 19.4 0.3 0.033 14.6 0.1 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain DIM1 PF02966.16 EGG18462.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Mitosis protein DIM1 Phosducin PF02114.16 EGG18462.1 - 0.018 14.0 0.1 0.033 13.1 0.0 1.5 2 0 0 2 2 2 0 Phosducin Thioredoxin_3 PF13192.6 EGG18462.1 - 0.13 12.4 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Polyketide_cyc PF03364.20 EGG18463.1 - 7.8e-20 71.4 0.0 3.2e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EGG18463.1 - 0.001 19.4 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport FRG2 PF15315.6 EGG18463.1 - 0.0071 16.6 0.0 0.0095 16.2 0.0 1.1 1 0 0 1 1 1 1 Facioscapulohumeral muscular dystrophy candidate 2 PsiB PF06290.11 EGG18463.1 - 0.056 12.9 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) Baculo_VP91_N PF08475.10 EGG18463.1 - 0.21 11.3 5.4 0.58 9.8 2.3 2.1 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal Oxysterol_BP PF01237.18 EGG18464.1 - 4.6e-46 157.4 0.7 1.2e-40 139.6 0.0 2.2 2 0 0 2 2 2 2 Oxysterol-binding protein LRR_4 PF12799.7 EGG18465.1 - 0.022 15.2 14.7 3.8 8.1 0.3 6.2 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) RTX_C PF08339.10 EGG18465.1 - 0.12 12.4 0.4 0.43 10.6 0.1 1.9 1 1 0 1 1 1 0 RTX C-terminal domain CLU PF13236.6 EGG18466.1 - 2.2e-57 194.4 0.0 5.2e-57 193.2 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGG18466.1 - 0.0079 16.2 0.2 0.0079 16.2 0.2 3.5 3 1 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TFIIA PF03153.13 EGG18466.1 - 0.052 13.5 37.3 0.073 13.1 37.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM131_like PF12371.8 EGG18467.1 - 2.3e-12 47.0 5.8 3.7e-10 39.9 0.5 4.8 5 0 0 5 5 5 1 Transmembrane protein 131-like DUF1573 PF07610.11 EGG18467.1 - 5.5e-08 32.7 1.5 0.02 14.9 0.1 4.6 4 0 0 4 4 4 2 Protein of unknown function (DUF1573) TFIIA PF03153.13 EGG18467.1 - 2.6 7.9 34.4 0.33 10.9 26.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DAPDH_C PF16654.5 EGG18467.1 - 4.2 7.2 8.2 7.1 6.5 0.1 3.4 3 0 0 3 3 3 0 Diaminopimelic acid dehydrogenase C-terminal domain DUF3446 PF11928.8 EGG18467.1 - 4.9 7.5 37.5 0.18 12.1 0.8 4.7 4 0 0 4 4 4 0 Early growth response N-terminal domain RabGAP-TBC PF00566.18 EGG18469.1 - 1.6e-51 175.0 0.0 1.6e-51 175.0 0.0 2.4 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GRAM PF02893.20 EGG18469.1 - 2.1e-23 82.4 9.1 1.5e-13 50.6 0.3 3.1 3 0 0 3 3 3 2 GRAM domain bPH_2 PF03703.14 EGG18469.1 - 0.043 14.0 0.5 0.33 11.2 0.1 2.3 2 0 0 2 2 2 0 Bacterial PH domain DUF4739 PF15893.5 EGG18469.1 - 0.053 13.1 0.1 0.092 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4739) GIDA_assoc PF13932.6 EGG18469.1 - 0.29 11.3 3.1 0.75 9.9 3.1 1.6 1 0 0 1 1 1 0 GidA associated domain LRR_6 PF13516.6 EGG18471.1 - 1.8e-05 24.4 4.0 0.058 13.5 0.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeat IPK PF03770.16 EGG18473.1 - 3.9e-33 115.0 0.1 3.9e-33 115.0 0.1 2.0 2 1 0 2 2 2 1 Inositol polyphosphate kinase WD40 PF00400.32 EGG18473.1 - 1.9e-30 104.4 19.4 2.1e-05 25.2 1.0 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG18473.1 - 4.7e-09 36.4 1.4 0.016 15.5 0.0 5.1 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EGG18473.1 - 8.6e-06 25.6 0.6 0.00012 21.9 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGG18473.1 - 4.7e-05 23.2 3.1 0.015 15.2 0.1 2.7 2 0 0 2 2 2 2 F-box domain PQQ PF01011.21 EGG18473.1 - 0.00019 21.2 0.0 0.58 10.2 0.0 3.8 3 0 0 3 3 3 1 PQQ enzyme repeat RAB3GAP2_N PF14655.6 EGG18474.1 - 4.6e-138 461.0 0.4 4.6e-138 461.0 0.4 2.6 2 1 1 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.8 EGG18474.1 - 0.0014 18.3 7.7 0.0014 18.3 7.7 3.7 3 1 0 3 3 3 1 Spt20 family TFIIA PF03153.13 EGG18474.1 - 0.0018 18.4 15.3 0.0018 18.4 15.3 2.7 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF4050 PF13259.6 EGG18474.1 - 0.012 16.0 0.5 0.012 16.0 0.5 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4050) SurA_N_3 PF13624.6 EGG18474.1 - 0.022 14.5 0.5 0.022 14.5 0.5 3.3 3 0 0 3 3 3 0 SurA N-terminal domain PAP1 PF08601.10 EGG18474.1 - 0.18 11.5 23.4 7.8 6.1 21.4 2.9 2 1 0 3 3 3 0 Transcription factor PAP1 FYDLN_acid PF09538.10 EGG18474.1 - 4.7 7.9 26.8 1.1 10.0 18.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Synaptobrevin PF00957.21 EGG18476.1 - 0.067 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Synaptobrevin TIG PF01833.24 EGG18476.1 - 0.085 13.0 12.9 0.52 10.4 0.2 3.8 3 0 0 3 3 3 0 IPT/TIG domain Orn_Arg_deC_N PF02784.16 EGG18477.1 - 1.3e-79 267.0 0.0 2.1e-79 266.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGG18477.1 - 1e-17 64.2 0.0 1.6e-17 63.5 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DNApol_Exo PF18136.1 EGG18477.1 - 0.022 13.9 1.7 0.039 13.1 1.7 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain AP_endonuc_2 PF01261.24 EGG18477.1 - 0.031 13.7 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF5448 PF17526.2 EGG18477.1 - 0.05 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5448) YqfQ PF14181.6 EGG18477.1 - 9 6.5 6.7 84 3.3 7.5 1.9 1 1 1 2 2 2 0 YqfQ-like protein NAD_kinase PF01513.21 EGG18478.1 - 9.2e-57 192.4 0.1 1.5e-56 191.7 0.1 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EGG18478.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain HicA_toxin PF07927.12 EGG18478.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, HSD3 PF15244.6 EGG18478.1 - 4.3 6.7 16.7 6.4 6.2 16.7 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 DnaJ PF00226.31 EGG18479.1 - 5.5e-23 80.9 0.7 1e-22 80.0 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 EGG18479.1 - 1.6e-08 34.7 0.5 3.8e-08 33.5 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.17 EGG18479.1 - 0.0017 18.3 0.0 0.076 13.2 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat SR-25 PF10500.9 EGG18479.1 - 0.023 14.3 9.4 0.032 13.8 9.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_1 PF00515.28 EGG18479.1 - 0.066 13.1 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PAP1 PF08601.10 EGG18479.1 - 0.24 11.1 7.8 0.32 10.7 7.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 GTP_EFTU PF00009.27 EGG18480.1 - 1.4e-21 76.9 0.4 3e-21 75.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG18480.1 - 2.6e-07 30.7 0.0 5.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EGG18480.1 - 1e-06 29.0 0.2 5.3e-06 26.7 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 SRPRB PF09439.10 EGG18480.1 - 1e-05 25.1 0.2 0.0019 17.7 0.2 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DP PF08781.10 EGG18480.1 - 0.021 14.7 0.6 0.11 12.4 0.6 2.1 2 0 0 2 2 2 0 Transcription factor DP Gtr1_RagA PF04670.12 EGG18480.1 - 0.023 14.1 0.5 0.058 12.7 0.5 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region NTF2 PF02136.20 EGG18481.1 - 4.1e-23 82.2 2.1 7.2e-17 62.1 0.1 2.9 3 0 0 3 3 3 2 Nuclear transport factor 2 (NTF2) domain Glyoxalase PF00903.25 EGG18481.1 - 1.5e-22 80.1 2.2 1.3e-15 57.8 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGG18481.1 - 1.5e-11 44.5 0.2 3e-05 24.3 0.2 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGG18481.1 - 2.4e-08 34.3 0.2 0.00012 22.2 0.1 2.9 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EGG18481.1 - 0.00012 22.3 0.3 0.00053 20.2 0.2 2.1 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_6 PF18029.1 EGG18481.1 - 0.068 14.0 0.1 0.22 12.3 0.1 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain SPX PF03105.19 EGG18482.1 - 1 9.2 10.9 4.7 7.0 0.0 2.4 2 1 0 2 2 2 0 SPX domain ELO PF01151.18 EGG18483.1 - 8.8e-53 179.4 24.3 1.1e-52 179.1 24.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GATA PF00320.27 EGG18485.1 - 3.8e-14 52.0 3.6 8.6e-14 50.9 3.6 1.7 1 0 0 1 1 1 1 GATA zinc finger GATA PF00320.27 EGG18487.1 - 5.6e-16 57.9 4.3 1.3e-15 56.7 4.3 1.6 1 0 0 1 1 1 1 GATA zinc finger Peptidase_S49_N PF08496.10 EGG18487.1 - 0.23 11.5 5.9 0.41 10.7 1.8 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SlyX PF04102.12 EGG18487.1 - 9.2 7.0 18.4 1.3 9.7 9.9 3.2 3 0 0 3 3 3 0 SlyX Helicase_C PF00271.31 EGG18489.1 - 3.7e-31 107.7 0.0 6.1e-30 103.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG18489.1 - 7.2e-29 100.8 2.3 1.5e-28 99.8 2.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGG18489.1 - 9.2e-06 25.8 3.5 0.0011 19.0 5.7 2.6 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF4746 PF15928.5 EGG18489.1 - 0.007 15.8 13.2 0.011 15.1 13.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) Microtub_bd PF16796.5 EGG18489.1 - 0.027 14.4 1.0 0.34 10.9 0.1 2.8 2 0 0 2 2 2 0 Microtubule binding CSRNP_N PF16019.5 EGG18489.1 - 0.043 13.7 4.6 0.092 12.6 4.6 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus EGF_3 PF12947.7 EGG18489.1 - 0.057 13.6 8.6 0.19 12.0 8.6 1.8 1 0 0 1 1 1 0 EGF domain EGF_2 PF07974.13 EGG18489.1 - 0.23 11.9 13.9 0.56 10.6 13.9 1.7 1 0 0 1 1 1 0 EGF-like domain AAA_7 PF12775.7 EGG18489.1 - 0.39 10.2 5.8 1.1 8.7 0.0 3.0 3 0 0 3 3 3 0 P-loop containing dynein motor region HAUS6_N PF14661.6 EGG18489.1 - 3.4 7.2 7.4 5.9 6.4 7.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus EGF PF00008.27 EGG18489.1 - 5 7.5 10.1 10 6.5 10.1 1.6 1 0 0 1 1 1 0 EGF-like domain GRP PF07172.11 EGG18489.1 - 8.7 7.1 11.9 3.9 8.2 7.3 2.5 2 0 0 2 2 2 0 Glycine rich protein family PRKCSH PF07915.13 EGG18491.1 - 2.5e-11 44.4 0.7 2.5e-11 44.4 0.7 4.2 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EGG18491.1 - 0.0017 18.0 0.2 0.0072 16.0 0.1 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein CIMR PF00878.18 EGG18491.1 - 0.0025 17.9 0.2 0.0055 16.8 0.2 1.6 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat Macoilin PF09726.9 EGG18491.1 - 0.33 9.5 22.2 0.46 9.0 22.2 1.1 1 0 0 1 1 1 0 Macoilin family CDK2AP PF09806.9 EGG18491.1 - 0.39 10.7 22.7 0.18 11.9 8.6 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein FNIP PF05725.12 EGG18492.1 - 2e-36 123.9 20.5 8.2e-09 35.5 0.2 6.4 5 1 1 6 6 6 5 FNIP Repeat zf-ISL3 PF14690.6 EGG18493.1 - 0.053 14.2 0.3 0.096 13.4 0.3 1.5 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-Di19 PF05605.12 EGG18493.1 - 0.068 13.5 0.8 0.16 12.3 0.4 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Lipase_3 PF01764.25 EGG18494.1 - 1.8e-27 95.9 0.0 2.9e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) CBM49 PF09478.10 EGG18494.1 - 9.7e-06 25.8 0.2 3.5e-05 24.0 0.1 2.1 2 1 0 2 2 2 1 Carbohydrate binding domain CBM49 Abhydrolase_1 PF00561.20 EGG18494.1 - 0.0044 16.7 0.1 0.0086 15.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 EGG18494.1 - 0.012 15.2 0.1 0.63 9.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EGG18494.1 - 0.04 13.2 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG18494.1 - 0.041 14.5 0.1 0.078 13.6 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EGG18494.1 - 0.054 13.3 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EGG18494.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 EGG18494.1 - 0.21 11.0 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AbrB_C PF18277.1 EGG18495.1 - 0.066 12.9 1.7 0.23 11.1 0.1 2.3 2 0 0 2 2 2 0 AbrB C-terminal domain FNIP PF05725.12 EGG18496.1 - 0.0039 17.3 15.0 6 7.1 0.0 6.7 6 2 0 6 6 6 4 FNIP Repeat AlphaC_C PF17480.2 EGG18496.1 - 6.1 6.9 6.5 6.9 6.8 4.3 2.2 2 0 0 2 2 2 0 AlphaC C-terminal Ank_4 PF13637.6 EGG18497.1 - 3.1e-24 85.0 2.5 4.6e-08 33.4 0.0 6.0 4 2 0 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18497.1 - 5.8e-24 84.5 0.4 5e-06 27.0 0.1 4.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18497.1 - 1.7e-18 66.4 1.3 0.021 15.2 0.1 7.5 2 2 6 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18497.1 - 3.2e-14 51.6 0.1 2.7 8.8 0.0 9.2 6 3 3 9 9 9 2 Ankyrin repeat DUF3447 PF11929.8 EGG18497.1 - 0.00045 20.1 0.1 5.6 7.0 0.1 4.0 2 1 1 3 3 3 2 Domain of unknown function (DUF3447) Ank PF00023.30 EGG18497.1 - 0.12 12.9 1.0 1.8e+02 2.8 0.0 5.5 5 1 1 6 6 6 0 Ankyrin repeat PYRIN PF02758.16 EGG18497.1 - 0.13 12.5 0.0 3.8 7.7 0.0 3.2 2 1 1 3 3 3 0 PAAD/DAPIN/Pyrin domain vATP-synt_E PF01991.18 EGG18498.1 - 9.2e-69 230.8 11.5 1.3e-68 230.4 11.5 1.2 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit YfhO PF09586.10 EGG18498.1 - 0.18 10.0 0.7 0.2 9.9 0.7 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO F-box PF00646.33 EGG18499.1 - 0.0014 18.4 0.3 0.0029 17.4 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGG18499.1 - 0.002 18.0 0.2 0.0044 16.9 0.2 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 EGG18499.1 - 0.003 17.4 0.0 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like Mucin PF01456.17 EGG18499.1 - 0.0076 16.2 14.4 0.015 15.3 14.4 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein SDA1 PF05285.12 EGG18499.1 - 0.012 15.1 3.9 0.019 14.4 3.9 1.3 1 0 0 1 1 1 0 SDA1 Clathrin_H_link PF13838.6 EGG18499.1 - 0.04 13.8 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Clathrin-H-link DHDPS PF00701.22 EGG18499.1 - 0.044 12.5 0.1 0.095 11.4 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family PRANC PF09372.10 EGG18499.1 - 0.06 13.7 0.2 0.06 13.7 0.2 3.2 5 0 0 5 5 4 0 PRANC domain SSP160 PF06933.11 EGG18499.1 - 0.49 8.5 16.8 0.83 7.8 16.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Nop14 PF04147.12 EGG18499.1 - 0.51 8.5 11.3 1.2 7.3 11.3 1.5 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EGG18499.1 - 2.8 5.9 11.0 9 4.3 11.0 1.8 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 EGG18501.1 - 0.00011 22.9 0.0 0.17 12.8 0.1 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG18501.1 - 0.011 16.0 0.0 0.21 11.9 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Paramecium_SA PF01508.16 EGG18503.1 - 0.033 14.6 7.0 1.5 9.3 1.3 2.2 2 0 0 2 2 2 0 Paramecium surface antigen domain DIM PF08194.12 EGG18503.1 - 0.9 9.8 7.4 8.2 6.7 0.9 3.3 3 0 0 3 3 3 0 DIM protein TRM PF02005.16 EGG18504.1 - 7.1e-126 420.4 0.0 9.8e-126 419.9 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 EGG18504.1 - 0.053 12.9 0.8 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Lustrin_cystein PF14625.6 EGG18504.1 - 0.07 13.5 0.4 0.23 11.9 0.4 1.9 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain CLIP_SPH_mas PF18398.1 EGG18504.1 - 0.098 13.1 0.3 0.34 11.3 0.3 2.0 1 0 0 1 1 1 0 Clip-domain serine protease homolog masquerade zf-CCCH PF00642.24 EGG18504.1 - 0.3 11.0 5.0 0.059 13.3 0.8 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FXMRP1_C_core PF12235.8 EGG18504.1 - 5.8 7.6 8.3 2 9.1 2.0 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal PPTA PF01239.22 EGG18505.1 - 2.1e-12 46.3 27.1 0.00031 20.4 0.2 6.3 7 0 0 7 7 7 4 Protein prenyltransferase alpha subunit repeat FMN_red PF03358.15 EGG18506.1 - 4.6e-28 97.9 0.0 6.2e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGG18506.1 - 0.0001 22.1 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FNIP_M PF14637.6 EGG18507.1 - 6.9e-63 212.7 0.6 1.3e-62 211.7 0.6 1.5 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 EGG18507.1 - 1.1e-19 70.8 0.0 3.1e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 EGG18507.1 - 4.8e-11 43.9 0.7 4.8e-11 43.9 0.7 5.2 3 2 2 5 5 5 2 Folliculin-interacting protein N-terminus Longin_2 PF18639.1 EGG18507.1 - 0.021 14.7 0.0 0.078 12.8 0.0 1.9 1 0 0 1 1 1 0 Yeast longin domain DUF3892 PF13031.6 EGG18507.1 - 0.068 13.8 0.8 0.23 12.1 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) Ank_2 PF12796.7 EGG18508.1 - 0.00017 22.1 0.0 0.00022 21.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18508.1 - 0.00022 21.4 0.0 0.88 10.0 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG18508.1 - 0.012 16.2 0.0 0.021 15.4 0.0 1.4 1 1 0 1 1 1 0 Ankyrin repeats (many copies) ICEA PF05315.11 EGG18509.1 - 0.049 13.1 0.0 0.049 13.1 0.0 1.0 1 0 0 1 1 1 0 ICEA Protein AATase PF07247.12 EGG18510.1 - 5.5e-13 48.3 1.3 1e-12 47.4 1.3 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 EGG18510.1 - 4.7e-10 38.7 0.2 1.2e-08 34.1 0.1 2.2 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.16 EGG18510.1 - 0.055 13.2 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain CDC24_OB1 PF17246.2 EGG18510.1 - 0.057 13.5 0.1 0.22 11.7 0.1 2.0 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 1 Coiled PF05710.12 EGG18512.1 - 0.011 16.6 1.6 0.014 16.2 1.6 1.2 1 0 0 1 1 1 0 Coiled coil Ank_2 PF12796.7 EGG18513.1 - 6.3e-28 97.2 9.8 1.4e-05 25.6 0.0 7.5 3 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18513.1 - 2e-25 88.5 15.0 0.007 16.7 0.0 12.2 4 2 11 15 15 15 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG18513.1 - 3.3e-23 81.8 16.6 4.4e-05 24.0 0.8 10.5 5 2 7 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18513.1 - 6e-12 44.6 7.6 48 5.0 0.0 13.0 12 2 2 14 14 14 0 Ankyrin repeat DUF5049 PF16468.5 EGG18513.1 - 9.3e-09 35.1 0.1 0.53 10.2 0.0 6.3 5 1 1 6 6 6 2 Domain of unknown function (DUF5049) Ank PF00023.30 EGG18513.1 - 0.002 18.5 0.7 1.8e+02 2.8 0.0 7.2 7 3 0 7 7 7 0 Ankyrin repeat DUF3447 PF11929.8 EGG18513.1 - 0.064 13.2 15.1 2.4 8.2 0.1 5.9 4 1 4 8 8 8 0 Domain of unknown function (DUF3447) DUF1979 PF09322.10 EGG18513.1 - 0.17 11.8 0.0 2.1 8.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1979) Coiled PF05710.12 EGG18515.1 - 0.02 15.7 0.8 0.023 15.5 0.8 1.1 1 0 0 1 1 1 0 Coiled coil Ank_4 PF13637.6 EGG18516.1 - 3.6e-20 72.0 5.4 0.0005 20.6 0.0 7.0 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18516.1 - 5.9e-20 71.6 4.0 0.00017 22.1 0.0 5.7 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18516.1 - 2.2e-19 69.2 2.8 0.053 13.9 0.0 9.4 5 4 5 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18516.1 - 9.2e-08 31.8 4.8 70 4.5 0.0 10.1 11 2 2 13 13 13 0 Ankyrin repeat DUF5049 PF16468.5 EGG18516.1 - 0.0031 17.4 0.2 31 4.6 0.0 4.8 3 2 3 6 6 6 0 Domain of unknown function (DUF5049) Ank PF00023.30 EGG18516.1 - 0.023 15.2 0.2 1.2e+02 3.4 0.0 5.8 4 2 0 4 4 4 0 Ankyrin repeat DUF1979 PF09322.10 EGG18516.1 - 0.076 12.9 0.0 1.5 8.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1979) Coiled PF05710.12 EGG18518.1 - 0.0027 18.5 1.2 0.0031 18.3 1.2 1.1 1 0 0 1 1 1 1 Coiled coil HSP20 PF00011.21 EGG18519.1 - 2.8e-20 72.3 1.9 2.7e-13 49.9 0.3 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG18519.1 - 2.7e-05 23.6 0.1 0.0054 16.3 0.1 2.5 2 1 0 2 2 2 2 HSP20-like domain found in ArsA GvpH PF05455.11 EGG18519.1 - 0.0029 17.7 0.6 0.0087 16.1 0.0 2.0 2 0 0 2 2 2 1 GvpH Ribosomal_L20 PF00453.18 EGG18519.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L20 Apc15p PF05841.11 EGG18519.1 - 9.8 7.0 11.0 2.3 9.0 3.9 2.1 2 0 0 2 2 2 0 Apc15p protein HSP20 PF00011.21 EGG18520.1 - 0.00042 20.4 0.9 0.0011 19.0 0.0 2.2 3 0 0 3 3 3 1 Hsp20/alpha crystallin family ANAPC_CDC26 PF10471.9 EGG18520.1 - 0.013 16.3 7.3 0.013 16.3 7.3 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Roughex PF06020.11 EGG18520.1 - 0.063 12.4 6.1 0.11 11.6 6.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF4611 PF15387.6 EGG18520.1 - 0.33 11.2 5.5 0.14 12.4 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NINJA_B PF16136.5 EGG18520.1 - 2.1 8.7 6.6 0.18 12.2 1.3 1.9 2 0 0 2 2 2 0 Putative nuclear localisation signal Presenilin PF01080.17 EGG18520.1 - 9.5 4.9 7.4 1.5 7.5 2.6 1.9 2 0 0 2 2 2 0 Presenilin HSP20 PF00011.21 EGG18521.1 - 3.2e-20 72.2 4.1 1.1e-13 51.2 0.3 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG18521.1 - 8.8e-06 25.2 0.1 0.0046 16.5 0.2 2.7 2 1 1 3 3 3 2 HSP20-like domain found in ArsA GvpH PF05455.11 EGG18521.1 - 0.0087 16.1 1.4 0.012 15.7 0.0 1.9 2 0 0 2 2 2 1 GvpH FKBP26_C PF18046.1 EGG18521.1 - 0.15 12.2 1.6 11 6.2 0.2 2.3 2 0 0 2 2 2 0 FKBP26_C-terminal Methyltransf_16 PF10294.9 EGG18522.1 - 5.4e-22 78.3 0.0 1.2e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EGG18522.1 - 0.00012 21.6 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGG18522.1 - 0.00036 20.0 0.0 0.0006 19.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EGG18522.1 - 0.0023 17.7 0.0 0.0052 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG18522.1 - 0.0035 18.1 0.7 0.69 10.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG18522.1 - 0.013 16.2 0.0 0.029 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Mannosyl_trans2 PF04188.13 EGG18523.1 - 1.1e-77 262.2 35.2 3e-43 148.8 6.7 2.2 2 0 0 2 2 2 2 Mannosyltransferase (PIG-V) Ank_2 PF12796.7 EGG18523.1 - 2.6e-31 108.1 16.3 4.4e-08 33.6 0.0 10.3 6 3 4 11 11 11 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18523.1 - 3.7e-26 91.1 12.6 0.018 15.6 0.0 12.0 10 2 2 12 12 12 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18523.1 - 5.3e-19 68.0 14.2 0.28 11.6 0.0 13.2 8 2 8 16 16 15 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18523.1 - 2.2e-15 55.2 4.5 5.3 8.0 0.0 14.0 12 3 3 15 15 14 1 Ankyrin repeat DUF5049 PF16468.5 EGG18523.1 - 0.00047 20.0 0.8 51 3.9 0.0 6.9 7 1 1 8 8 8 0 Domain of unknown function (DUF5049) RsbU_N PF08673.10 EGG18523.1 - 0.0041 17.2 0.1 0.3 11.2 0.1 3.5 3 0 0 3 3 3 1 Phosphoserine phosphatase RsbU, N-terminal domain Ank PF00023.30 EGG18523.1 - 0.0092 16.4 0.7 1.8e+02 2.8 0.0 7.1 5 3 0 5 5 5 0 Ankyrin repeat Carbam_trans_N PF02543.15 EGG18523.1 - 0.012 15.3 0.0 1.5 8.4 0.0 2.7 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus DUF1957 PF09210.11 EGG18523.1 - 0.035 14.5 0.1 0.12 12.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) DUF733 PF05306.11 EGG18523.1 - 0.41 11.0 3.2 1.1 9.6 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF733) RasGAP PF00616.19 EGG18524.1 - 3.2e-50 170.7 5.5 3.2e-50 170.7 5.5 2.4 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGG18524.1 - 8.6e-18 64.8 7.5 8.6e-18 64.8 7.5 2.7 2 0 0 2 2 2 1 RasGAP C-terminus MCM_N PF14551.6 EGG18524.1 - 0.048 14.3 1.5 0.15 12.7 0.3 2.5 2 0 0 2 2 2 0 MCM N-terminal domain DAAD PF18752.1 EGG18526.1 - 2.9e-94 316.2 7.7 4.2e-94 315.7 7.7 1.2 1 0 0 1 1 1 1 Dictyosteliid AID/APOBEC-like Deaminase NAD1 PF18778.1 EGG18526.1 - 0.0039 17.3 0.5 0.025 14.7 0.1 2.2 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 EGG18526.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC3 PF18771.1 EGG18526.1 - 0.048 13.8 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 APOBEC3 PorA PF11271.8 EGG18526.1 - 0.1 11.9 0.4 0.2 10.9 0.4 1.4 1 0 0 1 1 1 0 Porin PorA DUF678 PF05077.12 EGG18526.1 - 0.12 12.6 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Ank_2 PF12796.7 EGG18527.1 - 1.1e-30 106.0 14.6 1.1e-07 32.4 0.2 7.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18527.1 - 2.8e-22 78.8 12.3 6e-05 23.5 0.0 9.3 7 3 3 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18527.1 - 4.4e-22 77.8 9.5 0.24 11.8 0.0 11.1 5 2 6 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18527.1 - 8.3e-15 53.4 9.5 4.8 8.1 0.0 13.0 14 0 0 14 14 14 2 Ankyrin repeat DUF5049 PF16468.5 EGG18527.1 - 3.1e-09 36.6 5.3 5.6 6.9 0.0 8.2 7 1 2 9 9 9 3 Domain of unknown function (DUF5049) Ank PF00023.30 EGG18527.1 - 0.0095 16.4 0.2 2.7e+02 2.3 0.0 6.7 8 2 0 8 8 8 0 Ankyrin repeat Peptidase_S48 PF03574.15 EGG18527.1 - 0.029 14.6 0.9 77 3.5 0.0 5.2 4 1 2 6 6 6 0 Peptidase family S48 TbpB_C PF17483.2 EGG18527.1 - 0.076 13.4 0.7 24 5.4 0.0 3.3 2 1 1 3 3 3 0 C-lobe handle domain of Tf-binding protein B DUF3447 PF11929.8 EGG18527.1 - 0.24 11.4 23.5 0.31 11.0 1.1 7.0 3 2 5 8 8 8 0 Domain of unknown function (DUF3447) Kelch_1 PF01344.25 EGG18529.1 - 1.5e-32 110.9 5.3 1.5e-09 37.3 0.2 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EGG18529.1 - 5.4e-31 105.9 8.1 1.1e-08 35.1 0.1 6.8 4 1 2 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGG18529.1 - 8.8e-24 83.3 10.1 1.1e-07 31.8 0.0 7.2 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EGG18529.1 - 5.2e-19 67.4 7.0 1.9e-05 24.4 0.0 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 EGG18529.1 - 2e-16 59.8 11.2 9.9e-06 25.7 0.0 6.6 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG18529.1 - 0.00066 19.6 0.3 0.00066 19.6 0.3 5.1 6 0 0 6 6 6 2 Kelch motif CENP-F_leu_zip PF10473.9 EGG18529.1 - 0.49 10.4 6.1 0.8 9.7 6.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KIND PF16474.5 EGG18530.1 - 0.0073 16.2 1.6 0.0079 16.1 1.6 1.0 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain CENP-B_dimeris PF09026.10 EGG18530.1 - 0.023 15.1 7.5 0.024 15.0 7.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 EGG18530.1 - 0.16 11.6 2.1 0.15 11.6 2.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting YL1 PF05764.13 EGG18530.1 - 0.18 11.9 3.2 0.16 12.0 3.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein PAC1 PF16094.5 EGG18530.1 - 0.33 10.1 1.9 0.37 9.9 1.9 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 DNA_pol_phi PF04931.13 EGG18530.1 - 1.2 7.1 8.3 1.1 7.3 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi LRR_6 PF13516.6 EGG18531.1 - 2.5e-05 23.9 37.6 0.1 12.7 0.0 9.4 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.7 EGG18531.1 - 2.7e-05 24.4 39.3 0.0038 17.6 1.0 8.4 8 1 0 8 8 8 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGG18531.1 - 0.036 14.0 0.3 0.11 12.5 0.3 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EGG18531.1 - 0.047 13.6 0.1 0.15 11.9 0.1 1.9 1 0 0 1 1 1 0 F-box domain LRR_1 PF00560.33 EGG18531.1 - 4.5 8.2 29.3 19 6.3 0.5 9.8 10 0 0 10 10 10 0 Leucine Rich Repeat DNA_pol_B_3 PF08408.10 EGG18532.1 - 0.16 12.2 3.1 0.17 12.1 1.6 1.9 2 0 0 2 2 2 0 DNA polymerase family B viral insert Thg1 PF04446.12 EGG18533.1 - 3.4e-50 169.2 0.5 4.7e-50 168.8 0.5 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EGG18533.1 - 4.4e-44 149.5 1.0 9.2e-44 148.5 1.0 1.5 1 1 0 1 1 1 1 Thg1 C terminal domain Mito_carr PF00153.27 EGG18534.1 - 1.3e-60 201.3 0.6 1.1e-19 70.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein VKOR PF07884.14 EGG18535.1 - 5.3e-20 71.9 15.4 9.7e-20 71.0 15.4 1.4 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Thioredoxin_2 PF13098.6 EGG18535.1 - 8.2e-05 23.0 0.5 0.0018 18.7 0.1 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain PI3K_C2 PF00792.24 EGG18535.1 - 0.019 14.9 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 LodA_C PF18417.1 EGG18535.1 - 0.045 13.5 1.4 0.069 12.9 1.4 1.3 1 0 0 1 1 1 0 L-lysine epsilon oxidase C-terminal domain Ank_4 PF13637.6 EGG18536.1 - 1.5e-30 105.2 7.6 8.7e-05 23.0 0.0 9.1 7 1 3 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18536.1 - 2e-30 104.4 4.4 0.0027 18.0 0.0 12.7 6 5 8 14 14 14 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18536.1 - 1e-28 99.7 11.4 6e-05 23.5 0.0 7.5 3 3 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG18536.1 - 2.5e-13 48.9 2.5 12 6.8 0.0 13.5 14 2 2 16 16 16 1 Ankyrin repeat Ank PF00023.30 EGG18536.1 - 1.7e-05 25.0 0.4 29 5.3 0.0 7.8 7 2 1 8 8 8 1 Ankyrin repeat RicinB_lectin_2 PF14200.6 EGG18537.1 - 0.0082 16.8 3.5 0.71 10.6 0.1 4.0 2 2 2 4 4 4 1 Ricin-type beta-trefoil lectin domain-like MIR PF02815.19 EGG18537.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 MIR domain UQ_con PF00179.26 EGG18538.1 - 4.8e-38 130.0 0.1 6.2e-38 129.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGG18538.1 - 0.09 13.1 4.1 0.083 13.2 1.2 2.2 1 1 1 2 2 2 0 RWD domain DNA_pol_phi PF04931.13 EGG18538.1 - 8.6 4.3 10.3 10 4.1 10.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_S10 PF00450.22 EGG18539.1 - 1.1e-109 367.6 1.8 1.4e-109 367.3 1.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Leg1 PF05612.12 EGG18540.1 - 2.8e-59 200.9 2.0 4.1e-59 200.4 2.0 1.1 1 0 0 1 1 1 1 Leg1 DSPc PF00782.20 EGG18541.1 - 2.9e-25 88.6 0.4 7.5e-25 87.3 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Nbl1_Borealin_N PF10444.9 EGG18541.1 - 1.5e-21 75.7 0.1 2.7e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Y_phosphatase2 PF03162.13 EGG18541.1 - 0.003 17.1 1.1 0.0047 16.5 0.1 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EGG18541.1 - 0.004 17.3 0.4 0.017 15.2 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EGG18541.1 - 0.016 14.8 0.9 0.025 14.1 0.0 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase CDKN3 PF05706.12 EGG18541.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Rhodanese PF00581.20 EGG18541.1 - 0.033 14.7 0.1 0.94 10.0 0.0 2.5 2 0 0 2 2 2 0 Rhodanese-like domain Y_phosphatase3 PF13350.6 EGG18541.1 - 0.11 12.5 0.1 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family E7 PF00527.18 EGG18541.1 - 0.12 12.5 2.0 0.71 10.1 0.2 2.4 2 0 0 2 2 2 0 E7 protein, Early protein Thioredoxin PF00085.20 EGG18542.1 - 8.3e-31 106.0 0.1 1.1e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGG18542.1 - 9.3e-05 22.7 0.0 0.00032 21.0 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 EGG18542.1 - 9.4e-05 21.9 0.3 0.00012 21.6 0.3 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 EGG18542.1 - 0.0001 22.3 1.4 0.028 14.3 0.1 1.9 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EGG18542.1 - 0.00029 21.3 0.1 0.00046 20.6 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EGG18542.1 - 0.0036 17.2 0.1 0.0069 16.3 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_4 PF13462.6 EGG18542.1 - 0.022 14.9 0.0 0.29 11.3 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin LRAT PF04970.13 EGG18542.1 - 0.067 13.5 1.3 0.083 13.2 0.1 1.8 3 0 0 3 3 3 0 Lecithin retinol acyltransferase Thioredoxin_7 PF13899.6 EGG18542.1 - 0.12 12.5 0.1 0.29 11.3 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like WD40 PF00400.32 EGG18543.1 - 3.1e-23 81.6 12.6 0.00018 22.2 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG18543.1 - 6.6e-07 29.6 0.0 4.9 7.5 0.0 5.3 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGG18543.1 - 0.00017 20.5 1.4 0.25 10.0 0.0 3.5 3 1 0 4 4 4 2 Nup133 N terminal like Ge1_WD40 PF16529.5 EGG18543.1 - 0.0011 18.0 0.0 0.28 10.1 0.0 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EGG18543.1 - 0.0054 15.8 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region PQQ PF01011.21 EGG18543.1 - 0.0086 16.0 2.8 0.12 12.3 0.5 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.6 EGG18543.1 - 0.058 13.9 3.0 0.49 10.9 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain Vma12 PF11712.8 EGG18544.1 - 0.055 13.5 0.7 0.057 13.5 0.7 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Gelsolin PF00626.22 EGG18545.1 - 8.7e-24 83.2 2.4 6.5e-08 32.4 0.0 7.2 6 1 0 6 6 6 6 Gelsolin repeat OTCace PF00185.24 EGG18545.1 - 1.7 8.7 5.4 0.37 10.8 1.0 2.1 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Beta-lactamase PF00144.24 EGG18547.1 - 5.1e-44 150.9 0.0 6.9e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 EGG18547.1 - 0.058 12.8 0.0 0.31 10.4 0.0 2.1 2 1 1 3 3 3 0 D-alanyl-D-alanine carboxypeptidase DUF3439 PF11921.8 EGG18548.1 - 0.028 14.4 3.6 0.051 13.5 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Cyclin PF08613.11 EGG18550.1 - 5.4e-33 114.6 0.1 5.4e-33 114.6 0.1 2.5 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGG18550.1 - 7.8e-12 45.0 0.0 1.7e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain F-box-like PF12937.7 EGG18551.1 - 0.0069 16.3 0.2 0.017 15.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like FNIP PF05725.12 EGG18551.1 - 0.24 11.6 24.3 1.4 9.1 0.5 6.9 6 2 0 6 6 6 0 FNIP Repeat F-box-like PF12937.7 EGG18552.1 - 0.026 14.4 0.1 0.059 13.3 0.1 1.6 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 EGG18553.1 - 0.059 13.3 0.3 0.14 12.1 0.3 1.6 1 0 0 1 1 1 0 F-box-like NGP1NT PF08153.12 EGG18554.1 - 2e-42 144.4 0.2 2e-42 144.4 0.2 2.6 2 1 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EGG18554.1 - 1.4e-16 60.5 2.3 5.9e-14 52.1 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG18554.1 - 8.7e-06 25.3 0.1 0.00025 20.6 0.1 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGG18554.1 - 0.0009 19.2 0.0 0.0039 17.1 0.0 2.1 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EGG18554.1 - 0.0034 16.9 0.1 0.79 9.2 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGG18554.1 - 0.019 15.2 0.1 13 6.1 0.0 3.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF1676 PF07898.13 EGG18555.1 - 3.2e-06 27.3 8.3 3.7e-06 27.1 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) CRA PF06589.11 EGG18555.1 - 0.018 15.1 3.2 0.021 14.9 3.2 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) EMC3_TMCO1 PF01956.16 EGG18555.1 - 0.2 11.3 17.1 0.26 11.0 17.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like zf-LITAF-like PF10601.9 EGG18555.1 - 0.23 11.8 3.8 8.5 6.7 0.6 2.2 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-RING_2 PF13639.6 EGG18556.1 - 8.1e-11 42.1 6.7 8.1e-11 42.1 6.7 2.4 2 0 0 2 2 2 1 Ring finger domain zinc_ribbon_9 PF14369.6 EGG18556.1 - 9.5e-09 35.4 3.4 9.5e-09 35.4 3.4 2.2 2 0 0 2 2 2 1 zinc-ribbon zf-RING_11 PF17123.5 EGG18556.1 - 6e-08 32.3 4.8 1e-07 31.6 3.2 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGG18556.1 - 5.2e-07 29.4 7.0 5.2e-07 29.4 7.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG18556.1 - 7.1e-05 22.6 6.5 7.1e-05 22.6 6.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGG18556.1 - 0.00013 22.2 9.2 0.00013 22.2 9.2 3.3 3 2 0 3 3 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EGG18556.1 - 0.00027 20.8 11.6 0.0011 18.7 3.6 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG18556.1 - 0.00031 20.6 3.5 0.00031 20.6 3.5 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGG18556.1 - 0.0011 18.9 0.9 0.0011 18.9 0.9 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGG18556.1 - 0.0019 18.2 6.4 0.0019 18.2 6.4 2.5 2 1 1 3 3 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGG18556.1 - 0.0049 16.7 4.1 0.0049 16.7 4.1 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EGG18556.1 - 0.021 14.5 3.4 0.021 14.5 3.4 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-FCS PF06467.14 EGG18556.1 - 0.047 13.6 1.4 3.4 7.7 0.4 2.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Prok-RING_1 PF14446.6 EGG18556.1 - 0.17 11.8 14.0 2.6 8.0 0.7 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 A2L_zn_ribbon PF08792.10 EGG18556.1 - 1.3 8.8 5.8 3.1 7.6 1.4 2.7 2 0 0 2 2 2 0 A2L zinc ribbon domain RPA43_OB PF17875.1 EGG18556.1 - 6.9 7.3 13.7 10 6.8 0.2 3.4 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I FAM176 PF14851.6 EGG18556.1 - 9 5.9 21.4 2.2 7.9 1.9 3.6 3 0 0 3 3 3 0 FAM176 family RhoGEF PF00621.20 EGG18557.1 - 2.2e-44 151.9 1.6 2.3e-44 151.8 0.2 1.8 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 EGG18557.1 - 8.4e-07 29.5 2.1 1.9e-06 28.3 0.7 2.4 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 EGG18557.1 - 0.0013 18.5 0.5 0.0034 17.2 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 EGG18557.1 - 0.0034 17.2 0.2 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 PH domain IQ PF00612.27 EGG18557.1 - 0.0074 16.0 0.7 0.017 14.9 0.7 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH_10 PF15411.6 EGG18557.1 - 0.089 13.1 1.8 2.9 8.2 1.8 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain Plasmodium_HRP PF05403.11 EGG18558.1 - 2.4e-12 47.1 45.3 5.9e-08 32.8 27.9 2.2 2 0 0 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) YjeF_N PF03853.15 EGG18559.1 - 4.1e-39 134.2 0.0 5e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Trypsin_2 PF13365.6 EGG18560.1 - 6.9e-33 114.7 2.1 4.8e-20 73.0 0.2 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain Trypsin PF00089.26 EGG18560.1 - 2.2e-10 40.7 0.2 7.4e-09 35.7 0.1 2.9 2 1 0 2 2 2 1 Trypsin Peptidase_S46 PF10459.9 EGG18560.1 - 0.0044 15.7 3.2 0.83 8.2 0.0 3.2 3 0 0 3 3 3 2 Peptidase S46 SPX PF03105.19 EGG18560.1 - 5.6 6.8 8.7 7.3 6.4 8.7 1.1 1 0 0 1 1 1 0 SPX domain T3RM_EcoP15I_C PF18273.1 EGG18561.1 - 0.03 14.6 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 Type III R-M EcoP15I C-terminal domain 5_nucleotid PF05761.14 EGG18562.1 - 7.2e-172 572.4 2.4 8.4e-172 572.2 2.4 1.0 1 0 0 1 1 1 1 5' nucleotidase family WD-3 PF09765.9 EGG18562.1 - 0.069 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 WD-repeat region TTL PF03133.15 EGG18564.1 - 1.3e-23 83.5 0.6 1.3e-23 83.5 0.6 2.3 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGG18564.1 - 1.7e-08 34.0 0.0 2.9e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGG18564.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Menin PF05053.13 EGG18564.1 - 0.051 11.9 0.9 0.072 11.4 0.9 1.1 1 0 0 1 1 1 0 Menin Phageshock_PspD PF09584.10 EGG18564.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) MCU PF04678.13 EGG18565.1 - 2.5e-46 158.0 0.0 4.3e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial calcium uniporter LRR_8 PF13855.6 EGG18566.1 - 1.7e-21 75.7 24.8 3.4e-07 29.9 8.5 4.1 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EGG18566.1 - 1.5e-18 66.5 38.5 1.8e-06 28.2 1.7 5.3 2 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGG18566.1 - 0.0013 19.0 28.4 1.9 9.3 0.5 8.5 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.6 EGG18566.1 - 0.0039 16.7 12.8 0.0071 15.9 6.5 2.5 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 EGG18566.1 - 0.35 11.0 0.1 0.35 11.0 0.1 7.7 8 0 0 8 8 8 0 Leucine Rich repeat GCIP PF13324.6 EGG18567.1 - 2.1e-42 145.5 21.1 9.5e-31 107.4 4.8 2.1 1 1 1 2 2 2 2 Grap2 and cyclin-D-interacting Nop14 PF04147.12 EGG18567.1 - 0.0013 17.0 21.5 0.0013 17.0 21.5 1.7 2 0 0 2 2 2 1 Nop14-like family BUD22 PF09073.10 EGG18567.1 - 0.0093 15.4 18.1 0.013 14.9 18.1 1.2 1 0 0 1 1 1 1 BUD22 CNDH2_C PF16858.5 EGG18567.1 - 0.022 14.7 14.3 0.031 14.2 14.3 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DDHD PF02862.17 EGG18567.1 - 0.054 13.6 1.6 0.073 13.2 1.6 1.3 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 EGG18567.1 - 0.057 12.4 3.0 0.081 11.9 3.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF5523 PF17661.1 EGG18567.1 - 0.064 12.9 18.0 0.098 12.3 18.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) SID-1_RNA_chan PF13965.6 EGG18567.1 - 0.13 10.6 1.4 0.14 10.6 1.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2201_N PF13203.6 EGG18567.1 - 0.14 11.7 3.6 6.3 6.3 4.7 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain CDC45 PF02724.14 EGG18567.1 - 0.16 10.2 16.2 0.22 9.8 16.2 1.2 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 EGG18567.1 - 0.33 11.1 7.8 0.58 10.3 7.8 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 EGG18567.1 - 0.63 8.7 6.5 0.86 8.3 6.5 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 EGG18567.1 - 0.89 8.5 8.2 1.6 7.7 8.2 1.4 1 0 0 1 1 1 0 Solute carrier family 12 RP-C_C PF11800.8 EGG18567.1 - 1.1 9.3 4.8 1.9 8.6 4.8 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region SDA1 PF05285.12 EGG18567.1 - 1.3 8.3 27.0 2 7.8 27.0 1.2 1 0 0 1 1 1 0 SDA1 Connexin PF00029.19 EGG18567.1 - 2 8.1 5.1 3.1 7.5 5.1 1.3 1 0 0 1 1 1 0 Connexin RNA_pol_Rpc4 PF05132.14 EGG18567.1 - 2.2 8.7 6.3 3.6 8.0 6.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPN2_C PF18004.1 EGG18567.1 - 2.4 8.0 15.1 4.7 7.1 15.1 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TFIIF_alpha PF05793.12 EGG18567.1 - 2.5 6.6 26.4 3.4 6.2 26.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM60A PF15396.6 EGG18567.1 - 3.1 7.8 8.1 5.1 7.0 8.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A ALMT PF11744.8 EGG18567.1 - 3.4 6.4 9.4 4.9 5.9 7.4 2.0 1 1 0 2 2 2 0 Aluminium activated malate transporter Hid1 PF12722.7 EGG18567.1 - 3.4 5.7 8.5 6.1 4.8 8.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2722 PF10846.8 EGG18567.1 - 5.5 5.8 15.6 8.4 5.2 15.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RNA_polI_A34 PF08208.11 EGG18567.1 - 7.4 6.6 16.8 14 5.7 16.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 ORC_WH_C PF18137.1 EGG18567.1 - 8.1 6.5 11.7 18 5.4 11.7 1.5 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal SspB PF04386.13 EGG18567.1 - 8.3 6.3 12.0 15 5.4 12.0 1.5 1 0 0 1 1 1 0 Stringent starvation protein B NPR3 PF03666.13 EGG18567.1 - 8.6 5.0 13.1 16 4.1 13.1 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Oxysterol_BP PF01237.18 EGG18568.1 - 2.6e-47 161.4 8.2 3.5e-44 151.2 8.2 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Auxin_repressed PF05564.12 EGG18568.1 - 0.0031 18.2 0.7 0.23 12.2 0.0 2.4 2 0 0 2 2 2 2 Dormancy/auxin associated protein Oxysterol_BP PF01237.18 EGG18569.1 - 1.1e-92 310.7 36.0 1.6e-45 155.6 11.3 4.4 3 2 1 4 4 4 3 Oxysterol-binding protein Phage_tube PF04985.14 EGG18569.1 - 0.0068 16.1 0.1 0.97 9.1 0.0 2.6 2 0 0 2 2 2 1 Phage tail tube protein FII AKNA PF12443.8 EGG18569.1 - 0.099 13.3 0.9 7.4 7.3 0.0 3.1 4 0 0 4 4 4 0 AT-hook-containing transcription factor DUF823 PF05689.11 EGG18569.1 - 0.1 12.4 2.9 0.26 11.0 0.3 2.3 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF823) DUF3703 PF12487.8 EGG18569.1 - 0.12 12.2 0.0 22 4.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3703) DUF2312 PF10073.9 EGG18569.1 - 0.14 11.8 7.2 1.8 8.3 0.6 3.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) O-antigen_lig PF13425.6 EGG18569.1 - 0.28 9.9 3.3 0.44 9.3 3.3 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Pkinase PF00069.25 EGG18570.1 - 5.9e-67 225.8 0.0 9.3e-67 225.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG18570.1 - 2e-49 168.2 0.0 3e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1241 PF06840.11 EGG18570.1 - 6.4e-07 29.1 0.1 1.6e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Kinase-like PF14531.6 EGG18570.1 - 1.7e-05 24.3 0.0 0.0044 16.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGG18570.1 - 9.6e-05 21.3 0.0 0.00018 20.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGG18570.1 - 0.026 13.5 0.1 1.2 8.0 0.1 2.2 1 1 0 1 1 1 0 Haspin like kinase domain TFIIF_alpha PF05793.12 EGG18570.1 - 0.34 9.4 3.5 0.5 8.9 3.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Uricase PF01014.18 EGG18571.1 - 1.3e-59 200.1 7.3 2.5e-34 118.4 2.2 2.2 2 0 0 2 2 2 2 Uricase FolB PF02152.18 EGG18571.1 - 0.0062 17.1 0.6 0.094 13.3 0.0 2.2 2 0 0 2 2 2 1 Dihydroneopterin aldolase WaaY PF06176.11 EGG18571.1 - 0.022 14.4 0.1 0.043 13.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUSP PF06337.12 EGG18572.1 - 4.4e-13 49.7 0.2 6.6e-13 49.1 0.2 1.3 1 0 0 1 1 1 1 DUSP domain KH_1 PF00013.29 EGG18572.1 - 0.16 11.8 0.2 1.4 8.8 0.1 2.1 2 0 0 2 2 2 0 KH domain PWI PF01480.17 EGG18573.1 - 3.5e-24 84.9 0.8 3.5e-24 84.9 0.8 1.8 2 0 0 2 2 2 1 PWI domain Ank_4 PF13637.6 EGG18575.1 - 1.4e-28 98.9 15.6 4.7e-05 23.8 0.2 8.3 7 2 2 9 9 9 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18575.1 - 7.1e-27 93.8 12.4 5.6e-07 30.1 0.1 7.4 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18575.1 - 5.7e-22 77.5 14.0 0.044 14.1 0.1 10.9 5 4 6 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18575.1 - 2.6e-20 70.3 8.8 1.3 9.9 0.0 12.6 11 1 2 13 13 13 3 Ankyrin repeat Ank PF00023.30 EGG18575.1 - 0.0004 20.7 3.5 18 6.0 0.1 7.1 5 3 1 6 6 6 1 Ankyrin repeat DUF5049 PF16468.5 EGG18575.1 - 0.0023 17.8 0.0 15 5.6 0.0 5.4 5 1 1 6 6 6 1 Domain of unknown function (DUF5049) DUF3447 PF11929.8 EGG18575.1 - 0.0065 16.4 14.1 0.55 10.2 0.4 5.9 2 2 3 5 5 5 1 Domain of unknown function (DUF3447) DUF249 PF03158.13 EGG18575.1 - 0.024 14.4 1.4 0.45 10.2 0.1 3.2 1 1 2 3 3 3 0 Multigene family 530 protein DUF3430 PF11912.8 EGG18575.1 - 0.073 13.1 1.2 0.093 12.8 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3430) DUF1400 PF07176.11 EGG18575.1 - 0.17 12.2 0.0 1.6 9.0 0.0 2.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) Ank_4 PF13637.6 EGG18576.1 - 1.7e-27 95.4 7.3 9.7e-06 26.0 0.0 7.8 5 1 5 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18576.1 - 1.4e-20 73.1 14.1 0.0086 16.4 0.0 10.5 7 3 4 12 12 12 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18576.1 - 5.5e-20 71.7 11.4 5.2e-05 23.8 0.1 6.0 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG18576.1 - 6e-13 47.7 4.7 4.9 8.0 0.0 10.6 13 1 1 14 14 14 4 Ankyrin repeat Ank PF00023.30 EGG18576.1 - 0.12 12.9 1.0 75 4.0 0.0 5.0 5 1 1 6 6 6 0 Ankyrin repeat SR-25 PF10500.9 EGG18577.1 - 0.018 14.6 16.7 0.028 14.0 16.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dicty_REP PF05086.12 EGG18577.1 - 0.064 11.2 6.0 0.085 10.8 6.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sec62 PF03839.16 EGG18577.1 - 0.081 12.4 3.8 0.19 11.2 3.8 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 AP3D1 PF06375.11 EGG18577.1 - 0.13 12.5 9.4 0.24 11.6 9.4 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Coilin_N PF15862.5 EGG18577.1 - 0.21 11.4 12.3 0.37 10.6 12.3 1.3 1 0 0 1 1 1 0 Coilin N-terminus LCD1 PF09798.9 EGG18577.1 - 0.27 9.7 4.3 0.4 9.1 4.3 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein RNA_pol_Rpc4 PF05132.14 EGG18577.1 - 0.82 10.1 5.7 1.3 9.4 5.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tim54 PF11711.8 EGG18577.1 - 1.2 7.9 7.5 0.86 8.3 5.2 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RNA_polI_A34 PF08208.11 EGG18577.1 - 2.6 8.1 17.5 4 7.5 17.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CCDC106 PF15794.5 EGG18577.1 - 3.2 7.4 12.3 5 6.8 12.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Presenilin PF01080.17 EGG18577.1 - 9.1 4.9 8.4 7.8 5.1 4.3 2.0 2 0 0 2 2 2 0 Presenilin MAP17 PF15807.5 EGG18577.1 - 9.7 6.4 6.8 18 5.6 6.8 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Ank_5 PF13857.6 EGG18578.1 - 6.8e-36 121.9 18.0 0.0065 16.8 0.0 11.9 4 2 8 12 12 12 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG18578.1 - 8.9e-33 112.3 18.1 7.8e-06 26.3 0.2 9.1 4 2 6 11 11 11 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18578.1 - 3.5e-32 110.8 14.2 1.5e-05 25.5 0.1 6.6 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG18578.1 - 8.7e-21 71.8 10.3 1.1 10.1 0.0 13.5 12 2 2 14 14 14 3 Ankyrin repeat Ank PF00023.30 EGG18578.1 - 0.0013 19.1 4.2 84 3.9 0.1 7.9 5 3 1 6 6 6 0 Ankyrin repeat PYRIN PF02758.16 EGG18578.1 - 0.0033 17.5 0.1 1.3 9.2 0.0 3.6 3 0 0 3 3 3 1 PAAD/DAPIN/Pyrin domain DUF2790 PF10976.8 EGG18578.1 - 0.081 12.9 0.1 16 5.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2790) Helicase_PWI PF18149.1 EGG18578.1 - 0.56 10.4 5.2 4.5 7.5 0.0 4.5 4 2 1 5 5 5 0 N-terminal helicase PWI domain SAM_2 PF07647.17 EGG18579.1 - 1.4e-05 25.1 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGG18579.1 - 0.00036 20.9 0.0 0.00057 20.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FlbT PF07378.11 EGG18579.1 - 0.0061 16.6 0.6 0.012 15.7 0.4 1.5 1 1 0 1 1 1 1 Flagellar protein FlbT SAM_Ste50p PF09235.10 EGG18579.1 - 0.029 14.6 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 Ste50p, sterile alpha motif DUF533 PF04391.12 EGG18580.1 - 0.065 12.8 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) HAD_2 PF13419.6 EGG18581.1 - 0.073 13.1 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Spore_YunB PF09560.10 EGG18582.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein YunB (Spo_YunB) FNIP PF05725.12 EGG18583.1 - 1.9e-12 47.1 2.4 0.011 15.9 0.1 5.5 4 1 1 5 5 5 3 FNIP Repeat CDC45 PF02724.14 EGG18583.1 - 0.72 8.1 15.9 0.95 7.7 15.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 EGG18583.1 - 1.1 9.2 14.7 2.3 8.1 14.7 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 EGG18583.1 - 9.2 4.3 26.9 13 3.8 26.9 1.2 1 0 0 1 1 1 0 Nop14-like family Ank_2 PF12796.7 EGG18584.1 - 3.8e-31 107.5 9.0 4.7e-07 30.3 0.2 7.1 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18584.1 - 1e-30 105.7 10.9 8.3e-08 32.6 0.1 8.9 6 3 3 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18584.1 - 1.3e-29 101.9 12.5 2.2e-05 24.6 0.1 11.7 5 4 7 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18584.1 - 1.2e-17 62.1 7.7 0.84 10.4 0.0 13.4 15 0 0 15 15 15 3 Ankyrin repeat Ank PF00023.30 EGG18584.1 - 5.7e-05 23.4 6.2 45 4.7 0.0 9.1 6 4 2 8 8 8 0 Ankyrin repeat Ank_4 PF13637.6 EGG18585.1 - 1.4e-31 108.4 11.6 4.1e-06 27.2 0.1 8.8 5 3 2 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18585.1 - 1.3e-24 86.6 16.0 3.2e-09 37.2 0.1 6.5 2 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18585.1 - 3.6e-24 84.5 6.5 0.023 15.0 0.1 9.8 5 3 5 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18585.1 - 3.5e-16 57.7 7.9 2.4 9.0 0.0 10.7 10 1 1 11 11 11 6 Ankyrin repeat Ank PF00023.30 EGG18585.1 - 6e-06 26.5 1.8 28 5.4 0.0 7.2 7 2 1 8 8 8 0 Ankyrin repeat DUF5049 PF16468.5 EGG18585.1 - 0.0039 17.0 0.2 3.2 7.7 0.0 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF5049) DUF1400 PF07176.11 EGG18585.1 - 0.084 13.2 0.2 5.8 7.2 0.0 3.4 3 1 1 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) DUF4834 PF16118.5 EGG18586.1 - 0.21 12.6 10.3 1.3 10.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4094 PF13334.6 EGG18586.1 - 0.23 11.9 4.3 2.9 8.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF2615 PF11027.8 EGG18586.1 - 0.38 10.9 0.1 0.38 10.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Adeno_E3_CR2 PF02439.15 EGG18586.1 - 1.3 8.8 7.9 1.5 8.7 6.5 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Ank_5 PF13857.6 EGG18587.1 - 2.1e-30 104.4 6.1 2.9e-06 27.4 0.1 11.2 2 2 9 11 11 11 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18587.1 - 3.1e-30 104.6 14.1 1.3e-05 25.7 0.1 6.5 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18587.1 - 4.3e-28 97.3 11.5 4.7e-05 23.8 0.0 9.3 5 3 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18587.1 - 2.3e-16 58.2 4.9 12 6.8 0.1 12.4 12 2 2 14 14 14 1 Ankyrin repeat DUF5049 PF16468.5 EGG18587.1 - 3e-06 27.0 5.8 0.75 9.7 0.0 7.4 4 2 4 8 8 8 1 Domain of unknown function (DUF5049) Ank PF00023.30 EGG18587.1 - 0.0015 18.9 0.3 1.4e+02 3.2 0.0 7.0 6 2 2 8 8 8 0 Ankyrin repeat YmaF PF12788.7 EGG18587.1 - 0.22 12.1 5.4 0.9 10.1 0.2 3.1 2 1 1 3 3 3 0 YmaF family Lantibiotic_a PF14867.6 EGG18587.1 - 0.6 9.9 3.0 1.8 8.3 0.1 2.7 2 0 0 2 2 2 0 Lantibiotic alpha LapA_dom PF06305.11 EGG18588.1 - 0.029 14.2 0.0 0.076 12.8 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Amnionless PF14828.6 EGG18588.1 - 0.3 9.9 4.2 0.95 8.2 1.0 2.8 3 0 0 3 3 3 0 Amnionless DUF4834 PF16118.5 EGG18588.1 - 1.2 10.1 4.0 57 4.8 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Ank_5 PF13857.6 EGG18590.1 - 1.9e-09 37.6 0.1 4.9e-05 23.5 0.0 4.4 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18590.1 - 1.3e-08 35.3 0.6 0.00021 21.8 0.0 3.4 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18590.1 - 5.8e-05 23.6 2.2 0.62 10.7 0.0 5.3 3 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18590.1 - 0.00014 22.0 0.2 0.099 13.3 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat CtsR_C PF17727.1 EGG18590.1 - 0.059 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain Ank PF00023.30 EGG18590.1 - 0.18 12.3 0.8 9.1 6.9 0.0 3.7 5 1 0 5 5 5 0 Ankyrin repeat Ank_2 PF12796.7 EGG18593.1 - 5.8e-31 106.9 8.1 1e-05 26.0 0.1 7.3 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18593.1 - 8.5e-29 99.6 13.8 7.1e-06 26.5 0.1 9.3 8 2 0 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18593.1 - 1.2e-23 82.8 11.5 0.03 14.7 0.0 11.1 4 2 9 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18593.1 - 6e-17 60.0 8.4 6.7 7.6 0.0 13.8 14 1 1 15 15 15 3 Ankyrin repeat DUF5049 PF16468.5 EGG18593.1 - 3.6e-05 23.6 0.3 32 4.5 0.0 7.3 7 2 2 9 9 9 0 Domain of unknown function (DUF5049) Ank PF00023.30 EGG18593.1 - 0.0038 17.6 3.7 3.3e+02 2.0 0.0 8.0 7 4 2 9 9 9 0 Ankyrin repeat Ndc80_HEC PF03801.13 EGG18593.1 - 0.02 14.5 0.1 0.13 11.8 0.1 2.4 2 0 0 2 2 2 0 HEC/Ndc80p family RNase_P_p30 PF01876.16 EGG18593.1 - 0.047 13.2 0.2 7.3 6.0 0.0 3.0 3 0 0 3 3 3 0 RNase P subunit p30 DUF3447 PF11929.8 EGG18593.1 - 0.11 12.4 10.8 6.3 6.8 0.2 6.3 3 1 1 6 6 6 0 Domain of unknown function (DUF3447) SKA1 PF07160.12 EGG18594.1 - 0.045 13.6 4.9 0.051 13.4 4.9 1.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DegQ PF08181.11 EGG18594.1 - 0.26 11.4 3.8 0.45 10.7 3.8 1.4 1 0 0 1 1 1 0 DegQ (SacQ) family Med24_N PF11277.8 EGG18595.1 - 2.2e-06 26.1 0.1 2.2e-06 26.1 0.1 3.6 2 1 0 3 3 3 2 Mediator complex subunit 24 N-terminal BUD22 PF09073.10 EGG18595.1 - 3.1 7.0 47.2 0.013 14.9 30.2 2.3 2 0 0 2 2 2 0 BUD22 VraX PF17412.2 EGG18596.1 - 0.002 17.8 0.4 0.0067 16.0 0.4 1.9 1 0 0 1 1 1 1 Family of unknown function HILPDA PF15220.6 EGG18596.1 - 0.047 13.8 0.2 14 5.9 0.0 3.1 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated SelK_SelG PF10961.8 EGG18596.1 - 0.076 13.6 3.7 6.6 7.4 0.0 3.9 5 0 0 5 5 5 0 Selenoprotein SelK_SelG ADH_N_2 PF16884.5 EGG18597.1 - 2.7e-33 114.1 0.0 6e-33 113.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EGG18597.1 - 2.6e-19 69.5 0.0 3.7e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGG18597.1 - 6.8e-08 33.6 0.0 1.3e-07 32.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 1-cysPrx_C PF10417.9 EGG18597.1 - 0.051 13.4 0.0 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin Metallophos PF00149.28 EGG18598.1 - 3.6e-13 50.5 0.6 6.2e-13 49.7 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ubiquitin PF00240.23 EGG18599.1 - 7.4e-18 64.1 0.4 1.7e-17 62.9 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGG18599.1 - 8.5e-09 35.1 0.7 1.9e-08 34.0 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGG18599.1 - 8e-05 23.0 0.1 0.00022 21.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGG18599.1 - 0.028 14.5 0.0 0.097 12.8 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like FSA_C PF10479.9 EGG18599.1 - 5.7 4.9 13.7 11 4.0 13.7 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 EGG18599.1 - 8.2 4.3 14.4 14 3.5 14.4 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UTP15_C PF09384.10 EGG18600.1 - 6.8e-25 87.5 0.9 1.2e-24 86.6 0.9 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EGG18600.1 - 1.2e-21 76.6 2.1 1e-06 29.3 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG18600.1 - 1.9e-09 37.7 0.2 0.03 14.6 0.0 4.8 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG18600.1 - 1.7e-05 24.3 0.6 0.26 10.6 0.0 3.3 3 2 1 4 4 4 2 WD40-like domain PQQ_3 PF13570.6 EGG18600.1 - 0.16 12.5 0.8 12 6.5 0.0 3.2 3 1 0 3 3 3 0 PQQ-like domain Esterase PF00756.20 EGG18601.1 - 2.1e-58 197.9 0.0 2.4e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EGG18601.1 - 2.1e-06 27.2 0.0 4.1e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EGG18601.1 - 0.0053 15.7 0.0 0.0074 15.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EGG18601.1 - 0.018 14.5 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGG18601.1 - 0.018 14.7 0.1 0.04 13.6 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EGG18601.1 - 0.029 14.1 0.0 0.089 12.5 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Chlorophyllase PF07224.11 EGG18601.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Lipase_3 PF01764.25 EGG18601.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) EF-hand_1 PF00036.32 EGG18602.1 - 3.4e-25 85.7 8.7 2.1e-07 30.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGG18602.1 - 2.1e-24 83.3 3.3 4e-06 26.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGG18602.1 - 1.2e-20 73.7 6.6 8.8e-10 38.9 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG18602.1 - 4.4e-20 70.2 8.2 1.6e-06 27.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGG18602.1 - 1.2e-14 53.9 7.1 0.019 14.8 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGG18602.1 - 9e-06 26.0 1.8 0.077 13.3 0.3 3.0 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGG18602.1 - 0.00022 21.1 4.2 0.24 11.4 0.2 3.2 2 2 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EGG18602.1 - 0.0028 17.5 3.2 0.07 13.0 0.1 3.5 4 0 0 4 4 4 1 EF hand RNase_II_C_S1 PF18614.1 EGG18602.1 - 0.038 13.9 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain HSP70 PF00012.20 EGG18602.1 - 0.077 11.2 0.1 0.13 10.5 0.1 1.3 1 0 0 1 1 1 0 Hsp70 protein S_100 PF01023.19 EGG18602.1 - 0.089 12.5 1.0 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain EF-hand_3 PF09069.11 EGG18602.1 - 0.17 12.3 0.2 18 5.8 0.1 2.3 2 0 0 2 2 2 0 EF-hand FliC PF12445.8 EGG18603.1 - 0.0076 16.6 0.5 0.0076 16.6 0.5 2.9 3 0 0 3 3 3 1 Flagellin protein Herpes_glycoH_C PF17488.2 EGG18603.1 - 2.3 8.0 7.8 0.4 10.5 1.8 2.6 2 1 1 3 3 3 0 Herpesvirus glycoprotein H C-terminal domain Ank_4 PF13637.6 EGG18605.1 - 1.8e-33 114.5 16.2 1.7e-07 31.7 0.1 8.5 6 3 5 11 11 11 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18605.1 - 6.9e-29 100.3 8.9 3.9e-06 27.4 0.1 5.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18605.1 - 1.8e-23 82.3 9.2 0.00048 20.4 0.1 9.3 4 3 6 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18605.1 - 3.9e-17 60.6 13.4 1.6 9.6 0.0 12.0 13 1 1 14 14 14 6 Ankyrin repeat Ank PF00023.30 EGG18605.1 - 1.1e-08 35.1 0.8 12 6.5 0.0 9.3 6 4 0 6 6 6 1 Ankyrin repeat DUF3447 PF11929.8 EGG18605.1 - 0.12 12.4 20.7 16 5.6 0.0 6.2 2 2 5 7 7 7 0 Domain of unknown function (DUF3447) FtsX PF02687.21 EGG18606.1 - 6e-11 42.7 24.7 1.1e-08 35.4 7.7 5.1 4 1 0 4 4 4 2 FtsX-like permease family FAM176 PF14851.6 EGG18606.1 - 1.6 8.4 0.0 1.6 8.4 0.0 3.1 4 0 0 4 4 4 0 FAM176 family Ank_2 PF12796.7 EGG18608.1 - 3.1e-34 117.4 8.2 5.2e-09 36.6 0.1 6.1 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18608.1 - 8.3e-33 112.3 7.9 1.8e-05 25.2 0.0 8.4 7 3 1 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18608.1 - 3.8e-31 106.8 8.8 0.0035 17.6 0.0 12.3 3 2 10 13 13 13 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18608.1 - 3e-18 64.0 7.3 5 8.0 0.0 11.9 13 2 2 15 15 15 4 Ankyrin repeat Ank PF00023.30 EGG18608.1 - 4e-07 30.2 1.0 36 5.0 0.0 7.9 7 1 2 9 9 9 0 Ankyrin repeat DUF5049 PF16468.5 EGG18608.1 - 0.00011 22.1 9.6 5.3 7.0 0.1 8.2 6 3 4 10 10 10 1 Domain of unknown function (DUF5049) DUF3447 PF11929.8 EGG18608.1 - 0.00025 20.9 5.2 2 8.5 0.2 4.8 3 1 2 5 5 5 2 Domain of unknown function (DUF3447) ribosomal_L24 PF17136.4 EGG18609.1 - 0.047 14.1 0.1 0.095 13.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 DUF4898 PF16239.5 EGG18609.1 - 0.45 10.5 8.8 3.1 7.8 0.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4898) CDC45 PF02724.14 EGG18610.1 - 0.14 10.4 16.0 0.18 10.1 16.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EGG18610.1 - 0.22 11.3 12.3 0.34 10.7 12.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2403 PF10290.9 EGG18610.1 - 0.24 11.9 0.7 0.56 10.7 0.7 1.5 1 0 0 1 1 1 0 Glycine-rich protein domain (DUF2403) Presenilin PF01080.17 EGG18610.1 - 0.38 9.5 8.3 0.61 8.8 8.3 1.3 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 EGG18610.1 - 3 7.2 24.0 4.2 6.7 24.0 1.1 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.7 EGG18610.1 - 5.7 4.9 11.7 8.1 4.4 11.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tub_N PF16322.5 EGG18610.1 - 9.1 6.6 18.4 14 6.1 18.4 1.2 1 0 0 1 1 1 0 Tubby N-terminal LAP1C PF05609.12 EGG18610.1 - 9.2 5.2 14.8 13 4.8 14.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ALMT PF11744.8 EGG18610.1 - 10 4.9 6.8 17 4.1 6.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter SdrD_B PF17210.3 EGG18612.1 - 1.1e-160 524.8 46.6 1.1e-18 67.5 0.3 16.6 16 0 0 16 16 16 15 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG18612.1 - 2.2e-49 165.6 44.4 4.4e-05 23.7 2.4 16.5 15 1 0 15 15 15 14 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EGG18612.1 - 2e-25 88.9 43.7 0.0071 16.7 0.0 15.5 15 1 0 15 15 15 9 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 EGG18612.1 - 8.1e-15 54.6 33.6 0.23 11.5 0.0 13.2 14 1 0 14 14 14 6 CarboxypepD_reg-like domain Dioxygenase_C PF00775.21 EGG18612.1 - 2.8e-05 23.6 3.6 3.4 7.1 0.0 6.3 7 0 0 7 7 7 2 Dioxygenase bMG3 PF11974.8 EGG18612.1 - 0.0047 16.9 0.0 8 6.5 0.0 5.8 8 0 0 8 8 8 1 Bacterial alpha-2-macroglobulin MG3 domain DDE_Tnp_IS240 PF13610.6 EGG18612.1 - 0.017 15.4 0.0 0.95 9.7 0.0 2.4 2 0 0 2 2 2 0 DDE domain COLFI PF01410.18 EGG18612.1 - 0.028 13.7 0.1 0.064 12.6 0.1 1.5 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain MetallophosN PF16371.5 EGG18612.1 - 0.083 13.2 24.3 3.3 8.0 0.3 9.2 10 0 0 10 10 10 0 N terminal of Calcineurin-like phosphoesterase EMI PF07546.13 EGG18613.1 - 0.33 11.8 5.0 0.59 10.9 5.0 1.3 1 0 0 1 1 1 0 EMI domain CBM_3 PF00942.18 EGG18615.1 - 0.032 14.7 0.1 0.044 14.2 0.1 1.3 1 0 0 1 1 1 0 Cellulose binding domain CD52 PF15116.6 EGG18615.1 - 6.5 6.9 10.3 5.3 7.2 7.5 2.0 2 0 0 2 2 2 0 CAMPATH-1 antigen DIOX_N PF14226.6 EGG18616.1 - 9e-36 123.2 0.0 1.3e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGG18616.1 - 1.7e-23 83.0 0.0 3.3e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4756 PF15948.5 EGG18617.1 - 0.0014 18.5 1.9 0.0035 17.2 1.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4756) Glycos_transf_2 PF00535.26 EGG18618.1 - 1e-24 87.3 0.0 2e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EGG18618.1 - 2e-13 50.5 1.4 6.2e-13 48.8 0.1 2.2 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 EGG18618.1 - 8e-11 42.3 0.0 2.4e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 EGG18618.1 - 5.5e-06 26.0 0.3 1.3e-05 24.8 0.3 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase BshC PF10079.9 EGG18618.1 - 0.076 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Ank_4 PF13637.6 EGG18619.1 - 2.4e-40 136.4 21.0 3.3e-05 24.3 0.1 13.2 11 3 2 13 13 13 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18619.1 - 4.3e-40 136.2 29.5 2.9e-06 27.8 0.0 10.7 2 2 9 11 11 11 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18619.1 - 3.7e-39 132.3 21.2 0.00024 21.3 0.2 15.1 9 4 8 17 17 17 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18619.1 - 5.6e-20 69.3 13.7 2.2 9.1 0.0 16.8 19 3 1 20 20 20 5 Ankyrin repeat DUF5049 PF16468.5 EGG18619.1 - 1.1e-06 28.4 1.9 8 6.4 0.0 9.1 8 3 3 11 11 11 1 Domain of unknown function (DUF5049) Ank PF00023.30 EGG18619.1 - 6.2e-06 26.4 4.5 15 6.3 0.0 9.7 11 2 1 12 12 12 1 Ankyrin repeat HIGH_NTase1_ass PF16581.5 EGG18619.1 - 0.02 14.9 0.2 4.7 7.1 0.0 4.8 5 2 1 6 6 6 0 Cytidyltransferase-related C-terminal region SOG2 PF10428.9 EGG18621.1 - 1.3 8.1 14.5 1.5 7.9 14.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SOG2 PF10428.9 EGG18624.1 - 2.6 7.1 17.1 3.2 6.9 17.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ank_2 PF12796.7 EGG18625.1 - 5.5e-23 81.3 6.5 1.3e-06 28.9 0.1 6.4 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18625.1 - 2e-21 76.0 5.7 7e-05 23.3 0.1 8.7 5 2 4 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18625.1 - 1.4e-20 73.1 3.1 0.029 14.7 0.0 10.3 3 3 7 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18625.1 - 1.4e-12 46.6 0.8 15 6.5 0.0 10.6 10 1 1 11 11 11 1 Ankyrin repeat Ank PF00023.30 EGG18625.1 - 0.0017 18.7 0.6 2.1e+02 2.6 0.0 6.6 7 0 0 7 7 7 0 Ankyrin repeat DUF3447 PF11929.8 EGG18625.1 - 0.052 13.5 11.1 0.93 9.5 0.0 6.0 2 1 0 5 5 5 0 Domain of unknown function (DUF3447) YebO PF13974.6 EGG18625.1 - 2.6 8.2 5.7 12 6.1 2.7 2.3 2 0 0 2 2 2 0 YebO-like protein SF3a60_bindingd PF12108.8 EGG18625.1 - 7.5 6.5 7.5 0.29 11.1 0.8 2.0 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Ank_2 PF12796.7 EGG18626.1 - 1.2e-33 115.5 9.1 9.4e-08 32.5 0.1 6.3 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18626.1 - 4.6e-32 110.0 5.7 0.00018 22.0 0.0 9.2 6 3 3 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18626.1 - 9.8e-28 95.9 14.8 0.0025 18.1 0.0 11.3 6 3 5 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18626.1 - 3.1e-15 54.8 1.8 4.8 8.1 0.1 11.5 11 1 1 12 12 12 2 Ankyrin repeat DUF5049 PF16468.5 EGG18626.1 - 1.9e-06 27.7 1.4 3.9 7.5 0.0 7.5 7 2 2 9 9 9 1 Domain of unknown function (DUF5049) Ank PF00023.30 EGG18626.1 - 0.0012 19.2 0.1 1.1e+02 3.5 0.0 6.6 6 3 0 6 6 6 0 Ankyrin repeat DUF249 PF03158.13 EGG18626.1 - 0.012 15.3 3.3 1.3 8.7 0.0 4.2 2 2 1 3 3 3 0 Multigene family 530 protein Ank_2 PF12796.7 EGG18627.1 - 0.00035 21.1 0.1 0.035 14.7 0.0 3.4 3 2 0 3 3 3 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EGG18627.1 - 0.0025 17.7 0.0 0.0025 17.7 0.0 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EGG18627.1 - 0.051 14.1 0.0 1.9e+02 3.1 0.0 4.6 5 0 0 5 5 5 0 Ankyrin repeat Sec8_exocyst PF04048.14 EGG18628.1 - 2.1e-18 66.6 2.2 3.2e-18 66.0 0.5 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Leptin PF02024.15 EGG18628.1 - 0.29 10.9 5.0 4.7 7.0 0.1 3.5 3 0 0 3 3 3 0 Leptin IZUMO PF15005.6 EGG18628.1 - 3.2 8.3 9.3 0.87 10.1 0.7 3.4 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Vac7 PF12751.7 EGG18629.1 - 0.0001 21.9 1.0 0.0001 21.9 1.0 2.0 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 Ubie_methyltran PF01209.18 EGG18630.1 - 2.9e-88 295.1 0.0 4.5e-88 294.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EGG18630.1 - 2.2e-14 53.8 0.0 2.9e-13 50.3 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG18630.1 - 1.5e-13 51.3 0.0 4.1e-12 46.6 0.0 2.9 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG18630.1 - 1.4e-07 31.5 0.1 1.2e-06 28.4 0.0 2.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG18630.1 - 8.6e-06 25.7 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG18630.1 - 6.4e-05 23.6 0.1 0.00083 20.1 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGG18630.1 - 0.00057 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase ADH_zinc_N PF00107.26 EGG18630.1 - 0.16 11.9 0.0 0.52 10.3 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MetW PF07021.12 EGG18630.1 - 0.18 11.4 0.0 5.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW FNIP PF05725.12 EGG18631.1 - 4.1e-31 106.9 27.3 2.3e-08 34.0 0.2 7.6 6 2 1 7 7 7 5 FNIP Repeat zf-PARP PF00645.18 EGG18631.1 - 2e-19 70.2 0.4 2e-19 70.2 0.4 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region UDG PF03167.19 EGG18631.1 - 4.7e-05 23.4 0.0 0.00014 21.9 0.0 1.7 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily FHA_2 PF17913.1 EGG18631.1 - 0.0012 19.0 0.0 0.038 14.2 0.0 2.5 2 0 0 2 2 2 1 FHA domain Utp14 PF04615.13 EGG18631.1 - 3.3 6.2 56.8 0.36 9.3 8.4 3.0 3 0 0 3 3 3 0 Utp14 protein Presenilin PF01080.17 EGG18631.1 - 5.4 5.7 34.3 0.87 8.3 1.0 3.1 3 0 0 3 3 3 0 Presenilin LRR_6 PF13516.6 EGG18632.1 - 0.01 15.8 1.7 6.4 7.1 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeat CholecysA-Rec_N PF09193.10 EGG18632.1 - 0.024 14.6 0.1 0.058 13.4 0.1 1.6 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal LRR_8 PF13855.6 EGG18632.1 - 0.031 14.0 1.6 0.031 14.0 1.6 2.8 2 2 1 3 3 3 0 Leucine rich repeat Methyltransf_25 PF13649.6 EGG18632.1 - 0.034 14.8 0.0 0.045 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGG18632.1 - 0.04 14.6 0.3 0.058 14.1 0.3 1.2 1 0 0 1 1 1 0 Methyltransferase domain HECW1_helix PF18436.1 EGG18632.1 - 0.06 13.5 0.4 1.8 8.7 0.0 2.8 1 1 1 3 3 3 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 Methyltransf_11 PF08241.12 EGG18632.1 - 0.084 13.5 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain LRR_4 PF12799.7 EGG18632.1 - 0.47 10.9 4.1 0.27 11.7 1.0 2.1 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 EGG18634.1 - 8e-19 68.0 2.2 1.4e-07 32.0 0.1 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18634.1 - 1.2e-18 67.3 1.9 2.4e-05 24.8 0.1 6.7 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18634.1 - 1.5e-16 60.3 0.4 0.019 15.3 0.0 8.6 4 2 6 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18634.1 - 1.2e-11 43.7 1.4 0.2 12.3 0.1 8.4 8 2 2 10 10 10 2 Ankyrin repeat DUF3447 PF11929.8 EGG18634.1 - 0.0024 17.8 3.6 0.041 13.8 0.1 3.8 3 2 1 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 EGG18634.1 - 0.026 15.0 0.3 2.1e+02 2.6 0.0 5.6 4 2 1 5 5 5 0 Ankyrin repeat HTH_22 PF13309.6 EGG18634.1 - 0.099 12.7 0.1 1.5 9.0 0.0 3.0 3 1 1 4 4 4 0 HTH domain Ank_4 PF13637.6 EGG18636.1 - 1.7e-17 63.5 1.8 2.9e-06 27.7 0.0 6.2 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18636.1 - 3.6e-13 49.9 1.2 7.8e-05 23.2 0.1 4.8 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG18636.1 - 8.4e-11 41.1 2.7 1.6 9.5 0.0 8.6 8 1 1 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 EGG18636.1 - 6.6e-09 35.9 7.6 1.2 9.6 0.0 8.0 5 3 4 9 9 9 3 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 EGG18637.1 - 3.9e-23 79.2 3.7 4.2e-05 22.8 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGG18637.1 - 4.1e-19 66.8 5.0 0.0012 18.6 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGG18637.1 - 2e-17 63.4 5.3 3.1e-08 34.0 1.1 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGG18637.1 - 7.1e-16 56.9 2.4 0.0016 17.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGG18637.1 - 3.9e-12 45.8 1.4 0.0074 16.1 0.2 4.1 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGG18637.1 - 1.3e-06 28.7 2.8 8.8e-05 22.8 1.4 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 EGG18637.1 - 0.00042 20.3 2.9 1.2 9.0 0.0 3.7 2 2 2 4 4 4 1 Caleosin related protein EF-hand_13 PF17958.1 EGG18637.1 - 0.011 15.6 0.1 0.097 12.5 0.0 2.4 2 2 1 3 3 3 0 EF-hand domain VAPB_antitox PF02697.14 EGG18637.1 - 0.063 14.1 2.9 0.18 12.6 0.3 2.4 1 1 1 2 2 2 0 Putative antitoxin Plk4_PB2 PF18409.1 EGG18637.1 - 0.095 13.4 0.9 14 6.5 0.0 2.2 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Dockerin_1 PF00404.18 EGG18637.1 - 0.23 11.7 3.1 1.9 8.7 1.0 2.7 1 1 0 2 2 2 0 Dockerin type I domain EF-hand_4 PF12763.7 EGG18637.1 - 0.25 11.3 3.5 4 7.4 0.7 2.1 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand BAAT_C PF08840.11 EGG18637.1 - 0.48 10.3 2.5 0.84 9.5 0.9 1.9 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal TetR PF13972.6 EGG18638.1 - 0.014 15.2 0.1 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial transcriptional repressor LKAAEAR PF15478.6 EGG18638.1 - 0.15 12.4 0.1 0.56 10.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function with LKAAEAR motif Ank_4 PF13637.6 EGG18639.1 - 2.8e-81 266.9 22.9 1.5e-06 28.6 0.1 19.9 10 6 9 20 20 20 19 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18639.1 - 2.5e-80 265.1 32.3 3.2e-09 37.2 0.8 15.4 7 4 6 15 15 15 12 Ankyrin repeats (3 copies) PARP PF00644.20 EGG18639.1 - 1.5e-60 204.1 0.6 1.5e-60 204.1 0.6 3.7 2 1 2 5 5 5 1 Poly(ADP-ribose) polymerase catalytic domain Ank_5 PF13857.6 EGG18639.1 - 3.2e-59 196.2 28.1 4.5e-05 23.6 0.0 19.1 14 6 7 21 21 21 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18639.1 - 2.6e-47 153.3 29.1 0.053 14.1 0.0 23.5 24 0 0 24 24 24 11 Ankyrin repeat Ank PF00023.30 EGG18639.1 - 5.4e-34 115.2 40.9 0.01 16.2 0.1 22.5 25 0 0 25 25 25 9 Ankyrin repeat PARP_reg PF02877.14 EGG18639.1 - 3.7e-33 114.5 2.1 3.7e-33 114.5 2.1 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EGG18639.1 - 1.6e-14 53.7 0.0 1.6e-14 53.7 0.0 2.7 3 0 0 3 3 3 1 WGR domain Laminin_EGF PF00053.24 EGG18641.1 - 1.6e-10 40.9 85.5 0.00049 20.2 15.5 5.6 3 2 2 5 5 5 4 Laminin EGF domain Y_Y_Y PF07495.13 EGG18641.1 - 0.084 12.8 29.3 6.6 6.8 0.1 11.3 13 0 0 13 13 13 0 Y_Y_Y domain Med21 PF11221.8 EGG18643.1 - 0.0018 18.5 0.3 0.0018 18.5 0.3 4.1 3 1 1 4 4 4 1 Subunit 21 of Mediator complex Cyclase_polyket PF04673.12 EGG18643.1 - 0.064 13.5 0.1 0.47 10.7 0.0 2.3 2 0 0 2 2 2 0 Polyketide synthesis cyclase Striatin PF08232.12 EGG18643.1 - 0.09 13.4 0.0 0.09 13.4 0.0 5.9 3 2 2 5 5 5 0 Striatin family DUF131 PF01998.17 EGG18643.1 - 0.2 11.3 0.8 0.77 9.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF131 DUF4813 PF16072.5 EGG18644.1 - 1.4 8.5 8.1 1.5 8.5 8.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) PARP PF00644.20 EGG18645.1 - 2.3e-23 82.8 0.1 2.3e-23 82.8 0.1 2.4 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 EGG18645.1 - 7.9e-14 52.0 10.7 8.5e-08 32.7 1.8 2.8 3 0 0 3 3 3 2 WWE domain FAM176 PF14851.6 EGG18645.1 - 0.78 9.4 2.6 1 9.0 0.5 2.3 2 0 0 2 2 2 0 FAM176 family THUMP PF02926.17 EGG18646.1 - 2e-12 47.4 0.4 3.8e-12 46.5 0.4 1.5 1 0 0 1 1 1 1 THUMP domain EF-hand_1 PF00036.32 EGG18647.1 - 2.6e-16 57.9 9.3 8.2e-07 28.1 0.4 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGG18647.1 - 3.2e-16 57.8 7.7 4.9e-06 26.0 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EGG18647.1 - 9.9e-13 48.4 5.0 1.5e-10 41.4 2.5 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGG18647.1 - 8e-11 41.6 6.0 4.3e-08 32.9 1.7 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG18647.1 - 1.5e-09 36.9 9.5 0.00013 21.3 0.3 3.1 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 EGG18647.1 - 0.0024 18.0 0.4 0.01 16.0 0.4 2.1 1 0 0 1 1 1 1 Dockerin type I domain EF-hand_9 PF14658.6 EGG18647.1 - 0.007 16.7 0.1 0.026 14.9 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 EGG18647.1 - 0.16 12.0 10.2 0.55 10.2 0.3 3.2 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand DUF702 PF05142.12 EGG18647.1 - 0.54 10.7 4.2 0.94 9.9 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF4834 PF16118.5 EGG18647.1 - 9 7.3 16.4 9.8 7.2 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) Phosphodiest PF01663.22 EGG18648.1 - 4.9e-13 49.4 0.6 8.8e-13 48.6 0.1 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EGG18648.1 - 3.8e-05 23.2 0.2 5.8e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EGG18648.1 - 0.00027 20.4 0.2 0.0005 19.6 0.2 1.5 1 0 0 1 1 1 1 Sulfatase Connexin PF00029.19 EGG18648.1 - 0.018 14.8 3.4 0.37 10.5 0.0 3.0 3 0 0 3 3 3 0 Connexin EMC3_TMCO1 PF01956.16 EGG18648.1 - 0.12 12.0 0.1 0.12 12.0 0.1 4.4 5 1 0 6 6 6 0 Integral membrane protein EMC3/TMCO1-like ODV-E18 PF10717.9 EGG18648.1 - 3.9 7.4 10.4 1.7 8.6 5.4 3.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 TMCO5 PF14992.6 EGG18648.1 - 5.6 6.5 8.4 1.9 8.0 0.2 3.0 3 0 0 3 3 3 0 TMCO5 family GFA PF04828.14 EGG18649.1 - 1.5e-07 31.7 1.5 2e-07 31.3 0.1 1.8 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme p450 PF00067.22 EGG18650.1 - 5.4e-60 203.4 0.5 6.8e-60 203.1 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1633 PF07794.11 EGG18650.1 - 0.13 10.4 0.0 4 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1633) 7TMR-DISM_7TM PF07695.11 EGG18651.1 - 0.0058 16.5 2.7 0.0058 16.5 2.7 2.8 2 1 0 2 2 2 1 7TM diverse intracellular signalling DUF5436 PF17504.2 EGG18651.1 - 0.021 15.1 1.0 0.021 15.1 1.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5436) DUF2306 PF10067.9 EGG18651.1 - 0.034 14.4 1.1 0.034 14.4 1.1 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) YajC PF02699.15 EGG18651.1 - 0.043 13.7 1.8 0.043 13.7 1.8 2.7 4 0 0 4 4 4 0 Preprotein translocase subunit SDH_sah PF01972.16 EGG18651.1 - 0.38 9.7 2.9 0.73 8.8 2.9 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase PulG PF11773.8 EGG18651.1 - 7.5 6.5 7.3 2.9 7.8 0.1 3.1 3 0 0 3 3 3 0 Type II secretory pathway pseudopilin TMEM154 PF15102.6 EGG18651.1 - 8 6.4 5.2 19 5.1 1.2 2.4 2 0 0 2 2 2 0 TMEM154 protein family Ank_2 PF12796.7 EGG18652.1 - 3.4e-18 66.0 6.0 3.8e-06 27.4 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18652.1 - 5.2e-14 52.4 2.2 0.0028 18.2 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18652.1 - 1.2e-09 38.2 6.4 0.046 14.1 0.1 6.1 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18652.1 - 3.4e-09 36.2 1.4 12 6.8 0.0 7.5 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 EGG18652.1 - 0.013 15.9 5.9 1e+02 3.6 0.1 6.2 5 1 2 7 7 7 0 Ankyrin repeat Ank_2 PF12796.7 EGG18654.1 - 1.1e-06 29.1 0.5 0.0012 19.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18654.1 - 0.0079 16.8 0.0 0.48 11.1 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) YLP PF02757.17 EGG18654.1 - 5.3 7.3 5.8 44 4.5 0.5 2.8 2 0 0 2 2 2 0 YLP motif Ank_2 PF12796.7 EGG18655.1 - 5.8e-37 126.2 15.4 1.6e-07 31.8 0.3 6.5 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18655.1 - 5.6e-36 122.5 13.7 7.1e-07 29.7 0.1 9.8 4 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18655.1 - 1.4e-29 101.7 15.5 0.00014 22.1 0.1 12.7 4 3 10 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18655.1 - 9.5e-22 74.8 11.4 0.61 10.8 0.0 13.9 13 1 1 14 14 14 4 Ankyrin repeat Ank PF00023.30 EGG18655.1 - 1.7e-06 28.2 6.6 6.7 7.3 0.0 9.8 7 3 2 9 9 9 1 Ankyrin repeat Spt20 PF12090.8 EGG18655.1 - 0.0016 18.1 17.8 0.0029 17.3 17.8 1.4 1 0 0 1 1 1 1 Spt20 family BSP_II PF05432.11 EGG18655.1 - 0.038 13.7 8.6 0.061 13.0 8.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM60A PF15396.6 EGG18655.1 - 0.11 12.5 6.3 0.2 11.7 6.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Tim54 PF11711.8 EGG18655.1 - 0.2 10.4 5.3 0.3 9.8 5.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sin_N PF04801.13 EGG18655.1 - 0.25 10.5 14.0 0.38 9.9 14.0 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Peptidase_S64 PF08192.11 EGG18655.1 - 0.75 8.2 16.1 1.1 7.7 16.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Tam41_Mmp37 PF09139.11 EGG18655.1 - 0.88 8.9 12.5 1.4 8.3 12.5 1.2 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial CLN3 PF02487.17 EGG18655.1 - 4.6 6.2 6.3 6.9 5.6 6.3 1.2 1 0 0 1 1 1 0 CLN3 protein HCO3_cotransp PF00955.21 EGG18655.1 - 4.7 5.9 5.6 7.1 5.3 5.6 1.2 1 0 0 1 1 1 0 HCO3- transporter family Zip PF02535.22 EGG18655.1 - 6 6.0 7.2 8.6 5.5 7.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_C1 PF00112.23 EGG18656.1 - 7.6e-74 248.5 1.5 1.3e-73 247.7 1.5 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG18656.1 - 1.7e-13 50.7 5.2 3.8e-13 49.7 5.2 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGG18656.1 - 0.01 14.7 0.3 2.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase C1-like family Membrane_bind PF14564.6 EGG18657.1 - 1.5e-35 122.0 0.1 3.3e-35 120.8 0.0 1.6 2 0 0 2 2 2 1 Membrane binding SpoIIE PF07228.12 EGG18658.1 - 5.2e-10 39.6 0.0 1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EGG18658.1 - 1.3e-07 31.5 2.0 0.006 16.2 0.0 3.2 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGG18658.1 - 6.4e-06 26.0 0.4 7.7e-05 22.4 0.4 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C TFIIA PF03153.13 EGG18658.1 - 3.1 7.7 23.5 4.8 7.1 23.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 EGG18659.1 - 0.022 15.7 4.7 0.022 15.7 4.7 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Mucin PF01456.17 EGG18659.1 - 0.27 11.2 21.9 0.18 11.8 12.6 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein 4_1_CTD PF05902.13 EGG18659.1 - 1.3 9.1 19.8 3.6 7.7 8.0 2.9 2 0 0 2 2 2 0 4.1 protein C-terminal domain (CTD) DUF3439 PF11921.8 EGG18659.1 - 1.8 8.6 14.7 2.8 7.9 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ank_5 PF13857.6 EGG18660.1 - 3.5e-29 100.5 20.4 0.0024 18.1 0.0 11.5 3 2 10 13 13 13 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG18660.1 - 8.6e-29 99.5 14.1 3e-05 24.5 0.0 8.7 5 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18660.1 - 7.9e-26 90.5 15.5 1.4e-05 25.6 0.1 6.8 2 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG18660.1 - 3.7e-13 48.4 11.8 13 6.8 0.0 13.1 14 1 1 15 15 15 1 Ankyrin repeat Ank PF00023.30 EGG18660.1 - 0.00041 20.7 12.1 20 5.8 0.5 9.6 5 4 1 6 6 6 1 Ankyrin repeat Ndc80_HEC PF03801.13 EGG18660.1 - 0.0023 17.6 0.0 3.6 7.2 0.0 3.4 2 1 1 3 3 3 2 HEC/Ndc80p family MATalpha_HMGbox PF04769.12 EGG18660.1 - 0.042 13.2 1.2 9.7 5.4 0.0 3.1 3 0 0 3 3 3 0 Mating-type protein MAT alpha 1 HMG-box Glutaredoxin2_C PF04399.13 EGG18660.1 - 0.072 12.9 0.0 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain TIG PF01833.24 EGG18661.1 - 1.6e-28 98.6 199.1 3.3e-08 33.5 3.7 20.6 19 2 2 21 21 21 15 IPT/TIG domain hEGF PF12661.7 EGG18661.1 - 0.015 15.9 4.5 0.057 14.1 4.5 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF YabP PF07873.11 EGG18661.1 - 0.046 13.5 4.6 7.9 6.4 0.1 5.2 5 0 0 5 5 5 0 YabP family EGF_2 PF07974.13 EGG18661.1 - 0.048 14.0 13.6 0.13 12.7 13.6 1.8 1 0 0 1 1 1 0 EGF-like domain I-EGF_1 PF18372.1 EGG18661.1 - 0.28 11.3 8.6 0.72 10.0 8.6 1.7 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 EABR PF12180.8 EGG18663.1 - 0.0042 16.7 0.2 0.59 9.8 0.1 2.7 2 0 0 2 2 2 2 TSG101 and ALIX binding domain of CEP55 LuxT_C PF18285.1 EGG18663.1 - 0.17 12.4 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain SAM_3 PF18016.1 EGG18664.1 - 3.9e-08 33.0 0.1 9.6e-08 31.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase PF00069.25 EGG18664.1 - 5.5e-06 25.9 0.1 2.6e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 EGG18664.1 - 3.1e-05 23.7 0.0 6.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGG18664.1 - 0.0003 20.8 0.1 0.00092 19.2 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family SAM_1 PF00536.30 EGG18664.1 - 0.0013 19.1 0.0 0.0026 18.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FTA2 PF13095.6 EGG18664.1 - 0.025 14.2 0.1 0.074 12.7 0.1 1.8 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SAM_2 PF07647.17 EGG18664.1 - 0.03 14.4 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 EGG18664.1 - 0.062 12.1 0.1 0.073 11.8 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ank_2 PF12796.7 EGG18665.1 - 1.9e-25 89.3 16.5 0.0002 21.9 0.7 7.0 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18665.1 - 3.4e-24 84.9 14.5 0.0031 18.1 0.0 8.7 3 1 8 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18665.1 - 1.3e-20 73.1 15.0 0.15 12.4 0.0 11.2 4 3 8 12 12 12 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18665.1 - 5.8e-14 50.8 7.5 9.1 7.2 0.0 11.8 11 0 0 11 11 11 1 Ankyrin repeat Connexin PF00029.19 EGG18665.1 - 0.0046 16.8 1.8 0.0061 16.3 0.2 2.0 2 0 0 2 2 2 1 Connexin DUF5049 PF16468.5 EGG18665.1 - 0.0083 16.0 0.5 1.4 8.8 0.0 4.6 6 1 1 7 7 7 1 Domain of unknown function (DUF5049) Spt20 PF12090.8 EGG18665.1 - 0.0089 15.7 3.9 0.017 14.8 3.9 1.3 1 0 0 1 1 1 1 Spt20 family Ank PF00023.30 EGG18665.1 - 0.039 14.4 8.5 2.1e+02 2.6 1.0 8.5 4 3 1 5 5 5 0 Ankyrin repeat DUF789 PF05623.12 EGG18665.1 - 0.061 13.0 0.2 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF789) HTH_22 PF13309.6 EGG18665.1 - 0.078 13.1 0.1 51 4.0 0.0 4.2 5 0 0 5 5 5 0 HTH domain DUF1003 PF06210.11 EGG18665.1 - 1.6 8.9 4.6 4.8 7.3 4.5 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1003) Ank_4 PF13637.6 EGG18666.1 - 2.1e-10 40.9 0.9 2.8e-06 27.8 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18666.1 - 2.3e-09 37.7 3.2 3.4e-06 27.5 0.6 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18666.1 - 3.9e-09 36.6 0.1 0.029 14.7 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18666.1 - 2.5e-05 24.3 0.4 6.8 7.6 0.0 4.6 5 1 1 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EGG18667.1 - 0.09 13.1 0.1 7.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) NAD_binding_4 PF07993.12 EGG18668.1 - 1.1e-55 188.6 0.0 1.7e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGG18668.1 - 3.2e-46 157.8 0.0 3.5e-44 151.1 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EGG18668.1 - 4.4e-09 36.6 0.2 9e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EGG18668.1 - 5.2e-07 29.4 0.0 9.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG18668.1 - 0.012 15.0 0.1 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Tnp_zf-ribbon_2 PF13842.6 EGG18668.1 - 0.15 12.9 6.8 0.43 11.4 6.5 1.9 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-P11 PF03854.14 EGG18668.1 - 1.8 8.3 7.2 4.5 7.0 7.2 1.7 1 0 0 1 1 1 0 P-11 zinc finger Zn-ribbon_8 PF09723.10 EGG18668.1 - 4.5 7.5 7.3 9.3 6.5 7.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Ank_2 PF12796.7 EGG18669.1 - 1.5e-10 41.5 0.3 5.3e-10 39.8 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18669.1 - 8.2e-10 39.0 0.7 2.9e-08 34.1 0.1 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) F-box-like PF12937.7 EGG18669.1 - 6.2e-09 35.6 0.0 1.7e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like Ank PF00023.30 EGG18669.1 - 5.4e-07 29.8 0.4 0.00017 21.9 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EGG18669.1 - 3.8e-05 23.7 0.6 0.84 10.4 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGG18669.1 - 4.1e-05 23.8 0.4 0.0015 18.8 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) F-box PF00646.33 EGG18669.1 - 6.7e-05 22.7 0.0 0.00021 21.1 0.0 1.9 1 0 0 1 1 1 1 F-box domain DUF3439 PF11921.8 EGG18669.1 - 0.8 9.7 20.4 1.8 8.6 0.5 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Ank_2 PF12796.7 EGG18670.1 - 7.2e-29 100.2 22.8 1.1e-07 32.3 1.7 7.3 3 2 6 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18670.1 - 5.7e-25 87.4 13.5 0.0074 16.9 0.0 10.2 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18670.1 - 9.6e-20 70.4 12.8 0.088 13.2 0.0 11.5 4 3 8 13 13 13 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18670.1 - 4.7e-12 45.0 16.4 5.1 8.0 0.0 12.0 10 1 2 12 12 12 2 Ankyrin repeat DUF5049 PF16468.5 EGG18670.1 - 4.5e-06 26.5 0.0 7 6.6 0.0 6.9 7 1 1 8 8 8 2 Domain of unknown function (DUF5049) Ank PF00023.30 EGG18670.1 - 0.00099 19.5 4.0 3.1e+02 2.1 0.0 8.6 3 2 1 4 4 4 0 Ankyrin repeat TRI12 PF06609.13 EGG18671.1 - 0.024 13.0 0.2 0.035 12.5 0.2 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DIM PF08194.12 EGG18671.1 - 0.096 12.9 0.2 0.2 11.9 0.2 1.5 1 0 0 1 1 1 0 DIM protein mRNA_cap_enzyme PF01331.19 EGG18672.1 - 2e-32 112.6 1.8 2e-32 112.6 1.8 2.1 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EGG18672.1 - 8.6e-09 36.0 0.0 8.6e-09 36.0 0.0 2.5 3 0 0 3 3 3 1 mRNA capping enzyme, C-terminal domain mRNA_triPase PF02940.15 EGG18672.1 - 5.8e-06 26.2 0.4 5.8e-06 26.2 0.4 3.3 3 0 0 3 3 3 1 mRNA capping enzyme, beta chain Pox_ATPase-GT PF10640.9 EGG18672.1 - 0.00084 18.3 0.3 0.0021 17.0 0.3 1.6 1 0 0 1 1 1 1 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase DNA_ligase_A_M PF01068.21 EGG18672.1 - 0.0012 18.5 0.5 0.11 12.1 0.0 2.8 1 1 1 2 2 2 1 ATP dependent DNA ligase domain MoaF PF10703.9 EGG18672.1 - 0.013 15.4 0.0 0.044 13.7 0.0 1.9 1 0 0 1 1 1 0 MoaF N-terminal domain Ank_2 PF12796.7 EGG18674.1 - 9.7e-29 99.8 16.5 2.2e-07 31.3 0.5 7.3 1 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18674.1 - 3.2e-26 91.0 17.5 0.0018 18.6 0.0 11.2 3 3 8 11 11 11 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG18674.1 - 5.5e-26 90.6 13.8 1.4e-05 25.5 0.1 9.8 6 3 5 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18674.1 - 4.3e-17 60.5 14.1 0.77 10.5 0.0 12.8 13 2 2 15 15 15 4 Ankyrin repeat Ank PF00023.30 EGG18674.1 - 7.1e-05 23.1 3.3 71 4.1 0.0 8.5 7 3 0 7 7 7 0 Ankyrin repeat Phage_int_SAM_1 PF02899.17 EGG18674.1 - 0.0026 18.0 0.2 1.4 9.3 0.1 4.6 3 3 3 6 6 6 1 Phage integrase, N-terminal SAM-like domain DUF5049 PF16468.5 EGG18674.1 - 0.0041 17.0 0.3 7.2 6.6 0.0 6.0 7 1 1 8 8 8 1 Domain of unknown function (DUF5049) YozE_SAM_like PF06855.12 EGG18674.1 - 1.5 9.0 4.3 51 4.1 0.0 4.9 4 1 1 5 5 5 0 YozE SAM-like fold Ank_2 PF12796.7 EGG18675.1 - 3.1e-30 104.6 12.7 8.1e-07 29.5 0.0 7.8 2 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18675.1 - 3.1e-25 88.2 8.5 0.00095 19.7 0.0 9.2 6 3 3 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18675.1 - 4.1e-21 74.7 15.1 0.012 16.0 0.0 11.0 4 3 8 12 12 12 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18675.1 - 7.7e-13 47.4 12.6 4.6 8.1 0.0 13.3 12 3 3 15 15 15 2 Ankyrin repeat Ank PF00023.30 EGG18675.1 - 0.0001 22.6 3.6 34 5.1 0.5 7.8 8 2 0 8 8 8 0 Ankyrin repeat DUF5049 PF16468.5 EGG18675.1 - 0.0028 17.5 6.9 47 4.0 0.0 8.3 4 3 6 10 10 10 0 Domain of unknown function (DUF5049) DUF3447 PF11929.8 EGG18675.1 - 0.0076 16.2 9.2 0.28 11.2 0.0 5.6 3 2 2 5 5 5 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EGG18676.1 - 2.3e-11 44.1 0.3 1.8e-05 25.3 0.0 3.2 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG18676.1 - 1.2e-07 31.4 2.4 7.7 7.4 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EGG18676.1 - 7.9e-07 29.2 1.0 0.13 12.6 0.1 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG18676.1 - 1.6e-06 28.6 0.6 0.0027 18.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18677.1 - 6.6e-21 74.1 7.8 0.00022 21.5 0.2 7.8 4 3 4 8 8 8 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18677.1 - 2.8e-20 72.7 8.6 2.5e-06 28.0 0.0 5.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18677.1 - 2.8e-19 69.2 5.5 3.5e-06 27.4 0.3 6.4 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18677.1 - 9.1e-14 50.2 1.8 0.83 10.4 0.0 8.4 7 1 1 8 8 8 2 Ankyrin repeat Ank PF00023.30 EGG18677.1 - 3.5e-07 30.4 0.6 0.6 10.7 0.0 6.1 2 2 2 4 4 4 1 Ankyrin repeat Linker_histone PF00538.19 EGG18677.1 - 0.12 12.8 0.2 2.9 8.3 0.0 3.1 3 0 0 3 3 3 0 linker histone H1 and H5 family Ank_2 PF12796.7 EGG18678.1 - 3.4e-09 37.2 4.4 1.5e-05 25.5 0.3 4.2 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18678.1 - 4.4e-08 33.2 2.2 0.0028 17.9 0.0 4.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG18678.1 - 8.3e-08 32.6 1.6 0.066 13.8 0.1 4.3 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18678.1 - 0.00074 19.8 2.4 99 4.0 0.0 5.9 6 0 0 6 6 6 0 Ankyrin repeat Ank PF00023.30 EGG18678.1 - 0.24 11.9 1.0 49 4.6 0.0 3.9 3 1 0 3 3 3 0 Ankyrin repeat CBM_20 PF00686.19 EGG18679.1 - 8.5e-15 54.4 1.7 1.6e-07 31.1 0.1 3.5 3 0 0 3 3 3 3 Starch binding domain Mito_carr PF00153.27 EGG18680.1 - 5.5e-75 247.4 0.1 5.7e-27 93.5 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EGG18680.1 - 2.1e-19 69.7 11.5 3.8e-08 33.7 0.8 4.4 3 1 2 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.32 EGG18680.1 - 2.7e-17 60.9 19.9 4e-05 22.9 0.1 5.8 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.6 EGG18680.1 - 2e-16 59.6 9.2 7.2e-06 25.8 0.7 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 EGG18680.1 - 7.2e-14 50.5 20.7 2.2e-05 24.0 0.2 5.8 7 0 0 7 7 7 4 EF-hand domain EF-hand_5 PF13202.6 EGG18680.1 - 1.1e-11 43.7 10.6 0.0011 18.3 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EGG18680.1 - 0.02 15.2 0.3 91 3.5 0.1 4.1 4 1 0 4 4 4 0 EF-hand domain EF-hand_11 PF08976.11 EGG18680.1 - 0.045 14.6 0.8 0.51 11.2 0.0 3.0 3 1 1 4 4 4 0 EF-hand domain EF-hand_4 PF12763.7 EGG18680.1 - 0.13 12.3 2.1 1 9.3 0.1 2.9 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF1548 PF07579.11 EGG18682.1 - 0.054 13.8 0.1 0.1 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) Tape_meas_lam_C PF09718.10 EGG18682.1 - 0.094 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Ank_2 PF12796.7 EGG18683.1 - 8.3e-17 61.6 0.4 1.5e-08 35.1 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18683.1 - 3.3e-15 55.9 5.7 5e-05 23.5 0.1 5.7 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG18683.1 - 5.1e-14 52.4 2.6 1.6e-06 28.5 0.1 3.8 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18683.1 - 3.3e-08 33.1 1.1 0.87 10.3 0.0 5.9 5 1 1 6 6 6 2 Ankyrin repeat Ank PF00023.30 EGG18683.1 - 0.028 14.8 0.0 77 4.0 0.0 4.9 2 2 2 4 4 4 0 Ankyrin repeat Ank_5 PF13857.6 EGG18684.1 - 7.6e-07 29.3 0.0 0.01 16.1 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18684.1 - 1.3e-06 28.9 0.2 5.4e-06 26.9 0.1 1.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18684.1 - 0.00013 22.4 0.8 0.00045 20.7 0.1 2.3 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18684.1 - 0.00023 21.3 0.6 6.1 7.8 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EGG18685.1 - 2.3e-27 95.4 11.5 1.6e-07 31.8 0.3 6.2 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18685.1 - 1.2e-25 89.5 3.4 2.4e-05 24.8 0.0 6.9 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18685.1 - 2.4e-20 72.3 9.2 0.069 13.5 0.1 10.1 3 2 6 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18685.1 - 4.1e-16 57.5 4.3 1.5 9.6 0.0 10.6 12 0 0 12 12 12 3 Ankyrin repeat Ank PF00023.30 EGG18685.1 - 0.0013 19.1 2.4 47 4.7 0.2 7.5 4 3 0 4 4 4 0 Ankyrin repeat Atg31 PF09795.9 EGG18688.1 - 0.011 15.8 1.3 0.014 15.4 1.3 1.1 1 0 0 1 1 1 0 Autophagy-related protein 31 HSP20 PF00011.21 EGG18689.1 - 2.1e-12 47.1 0.0 2.3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Ank_2 PF12796.7 EGG18691.1 - 1.9e-19 70.0 1.5 2.1e-06 28.2 0.0 4.5 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18691.1 - 2.4e-18 65.9 0.1 0.0083 16.4 0.0 8.0 2 2 6 9 9 9 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG18691.1 - 3e-16 59.6 0.0 0.0003 21.3 0.0 5.7 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18691.1 - 9.4e-13 47.1 0.0 0.53 11.0 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat DUF3447 PF11929.8 EGG18691.1 - 0.00013 21.9 4.8 0.35 10.9 0.4 3.6 1 1 3 4 4 4 3 Domain of unknown function (DUF3447) Ank PF00023.30 EGG18691.1 - 0.0095 16.4 0.1 58 4.4 0.0 5.4 4 2 1 5 5 5 0 Ankyrin repeat DUF5049 PF16468.5 EGG18691.1 - 0.48 10.4 2.4 18 5.3 0.0 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF5049) MRNIP PF15749.5 EGG18692.1 - 0.0089 16.7 3.9 0.013 16.3 3.9 1.2 1 0 0 1 1 1 1 MRN-interacting protein DUF3449 PF11931.8 EGG18692.1 - 0.021 14.6 4.1 0.035 13.9 4.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3449) SUIM_assoc PF16619.5 EGG18692.1 - 1.7 8.8 11.3 0.98 9.5 9.9 1.4 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ank_2 PF12796.7 EGG18693.1 - 4.2e-29 101.0 6.1 1.3e-06 28.9 0.1 6.1 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18693.1 - 1.1e-25 89.7 1.3 1.4e-05 25.5 0.0 7.6 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18693.1 - 1.5e-21 76.2 3.8 0.0069 16.7 0.0 9.1 4 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18693.1 - 2.4e-15 55.1 0.3 4.8 8.1 0.0 10.2 9 1 1 10 10 10 2 Ankyrin repeat Ank PF00023.30 EGG18693.1 - 3.2e-05 24.2 0.6 14 6.3 0.0 6.9 4 2 2 6 6 6 1 Ankyrin repeat CAP_N PF01213.19 EGG18693.1 - 0.0012 18.4 1.3 0.0018 17.8 1.3 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal SMN PF06003.12 EGG18693.1 - 0.034 13.4 1.9 0.057 12.7 1.9 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PRIMA1 PF16101.5 EGG18693.1 - 0.21 11.6 2.0 0.44 10.6 2.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 EGG18693.1 - 0.24 11.5 3.8 0.45 10.6 3.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator NST1 PF13945.6 EGG18693.1 - 0.29 11.2 6.2 0.57 10.3 6.2 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Ank_4 PF13637.6 EGG18694.1 - 1.5e-08 35.0 1.7 0.05 14.2 0.0 5.4 2 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18694.1 - 2.8e-08 33.8 0.3 1.4 9.3 0.1 5.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18694.1 - 1.1e-06 29.1 1.9 0.066 13.8 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG18694.1 - 0.52 11.0 5.3 1.1e+02 3.9 0.0 5.3 7 0 0 7 7 7 0 Ankyrin repeat ATP-synt_F6 PF05511.11 EGG18695.1 - 0.087 13.3 0.2 0.38 11.2 0.0 1.8 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 DUF2465 PF10239.9 EGG18695.1 - 0.1 11.8 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) Ank_2 PF12796.7 EGG18697.1 - 2.3e-37 127.5 14.3 2.8e-07 31.0 0.6 7.0 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18697.1 - 4.5e-37 126.0 8.8 1.2e-06 28.9 0.0 10.8 8 1 3 11 11 11 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18697.1 - 6.5e-29 99.6 10.7 0.00025 21.3 0.0 12.0 3 2 11 14 14 14 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18697.1 - 9.7e-21 71.7 7.4 3.2 8.6 0.0 13.4 15 1 1 16 16 13 4 Ankyrin repeat DUF5049 PF16468.5 EGG18697.1 - 1.4e-06 28.0 1.5 0.59 10.1 0.0 6.5 7 1 1 8 8 7 1 Domain of unknown function (DUF5049) Ank PF00023.30 EGG18697.1 - 0.0065 16.9 10.4 17 6.1 0.1 8.4 7 3 1 8 8 7 0 Ankyrin repeat Connexin PF00029.19 EGG18697.1 - 0.017 14.9 0.7 0.036 13.8 0.7 1.5 1 0 0 1 1 1 0 Connexin Spt20 PF12090.8 EGG18697.1 - 0.021 14.5 15.5 0.043 13.4 15.5 1.4 1 0 0 1 1 1 0 Spt20 family HTH_22 PF13309.6 EGG18697.1 - 0.03 14.4 0.1 3.8 7.7 0.0 4.1 4 1 1 5 5 4 0 HTH domain Pex14_N PF04695.13 EGG18697.1 - 0.047 14.4 7.7 0.083 13.5 7.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region G0-G1_switch_2 PF15103.6 EGG18697.1 - 0.054 13.9 1.8 0.1 13.0 1.8 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF4666 PF15697.5 EGG18697.1 - 0.07 13.8 1.7 0.2 12.3 1.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) DUF3987 PF13148.6 EGG18697.1 - 0.083 11.9 1.4 0.16 11.0 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4834 PF16118.5 EGG18697.1 - 0.12 13.3 5.1 0.28 12.1 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 EGG18697.1 - 0.2 10.6 11.2 0.29 10.0 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Dsh_C PF12316.8 EGG18697.1 - 1.8 8.9 4.7 3.2 8.1 4.7 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Roughex PF06020.11 EGG18697.1 - 3.2 6.7 9.4 5 6.1 9.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Ank_2 PF12796.7 EGG18698.1 - 1.1e-34 118.8 10.2 1.4e-06 28.7 0.0 7.2 1 1 8 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18698.1 - 3.2e-29 100.9 10.8 1.3e-05 25.6 0.0 9.9 7 2 4 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18698.1 - 2.5e-27 94.6 12.3 0.006 16.9 0.0 12.2 5 3 8 13 13 13 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18698.1 - 2.1e-19 67.6 6.6 2.3 9.0 0.0 13.4 15 0 0 15 15 14 3 Ankyrin repeat DUF5049 PF16468.5 EGG18698.1 - 8.1e-07 28.8 0.5 2.5 8.0 0.0 6.6 6 1 1 7 7 7 1 Domain of unknown function (DUF5049) Ank PF00023.30 EGG18698.1 - 1.7e-06 28.2 4.4 28 5.4 0.0 9.0 7 4 1 8 8 8 0 Ankyrin repeat DUF5099 PF17025.5 EGG18698.1 - 0.13 12.7 4.1 2.2 8.7 0.1 3.8 3 2 1 4 4 4 0 Domain of unknown function (DUF5099) APOBEC3 PF18771.1 EGG18698.1 - 0.17 12.0 5.6 1.3 9.2 0.0 3.7 3 1 1 4 4 4 0 APOBEC3 SapB_1 PF05184.15 EGG18698.1 - 0.51 10.4 3.7 1.7 8.7 0.1 4.1 5 0 0 5 5 5 0 Saposin-like type B, region 1 DUF4116 PF13475.6 EGG18698.1 - 0.98 9.2 3.3 7.8 6.3 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4116) APP_Cu_bd PF12924.7 EGG18698.1 - 1.8 9.4 4.4 14 6.5 0.1 4.3 4 0 0 4 4 4 0 Copper-binding of amyloid precursor, CuBD Ank_4 PF13637.6 EGG18699.1 - 3.6e-19 68.9 0.3 3.8e-06 27.3 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18699.1 - 1.4e-18 66.7 1.0 0.00012 22.3 0.1 6.5 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18699.1 - 8.8e-18 64.7 2.1 5.6e-07 30.1 0.2 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG18699.1 - 1e-09 37.8 2.9 2.9 8.7 0.0 7.4 8 1 1 9 9 9 2 Ankyrin repeat HIGH_NTase1_ass PF16581.5 EGG18699.1 - 0.041 13.9 0.5 0.4 10.6 0.0 2.5 1 1 2 3 3 3 0 Cytidyltransferase-related C-terminal region Phage_tail_X PF05489.12 EGG18699.1 - 0.049 13.3 0.1 3.3 7.4 0.0 3.1 3 0 0 3 3 3 0 Phage Tail Protein X Ank PF00023.30 EGG18699.1 - 0.075 13.5 0.0 95 3.7 0.0 4.5 3 1 0 3 3 3 0 Ankyrin repeat SapB_1 PF05184.15 EGG18699.1 - 0.16 12.0 2.0 6.9 6.8 0.0 4.0 5 0 0 5 5 5 0 Saposin-like type B, region 1 Ank_2 PF12796.7 EGG18700.1 - 1.6e-19 70.3 0.8 5.6e-08 33.3 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18700.1 - 1.8e-16 60.3 1.9 0.00059 20.4 0.0 5.9 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18700.1 - 3.1e-12 45.5 2.9 0.67 10.7 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EGG18700.1 - 3.9e-10 39.8 5.5 0.039 14.3 0.0 6.0 1 1 5 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EGG18700.1 - 2.2e-05 24.7 0.2 26 5.5 0.0 5.6 3 1 0 3 3 3 1 Ankyrin repeat DUF5049 PF16468.5 EGG18700.1 - 0.0036 17.2 0.0 11 6.1 0.0 3.8 2 1 2 4 4 4 1 Domain of unknown function (DUF5049) AalphaY_MDB PF04611.12 EGG18701.1 - 0.2 11.6 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Ank_2 PF12796.7 EGG18702.1 - 6.3e-28 97.2 13.1 2.2e-07 31.3 0.9 6.4 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18702.1 - 8e-26 90.1 11.8 3.5e-05 24.3 0.1 8.9 6 3 2 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18702.1 - 4.6e-25 87.3 13.4 0.00093 19.5 0.1 11.3 4 3 7 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18702.1 - 1.1e-13 50.0 10.4 2.8 8.8 0.1 11.7 13 1 0 13 13 13 3 Ankyrin repeat Ank PF00023.30 EGG18702.1 - 0.00079 19.8 5.0 58 4.4 0.1 7.5 6 2 1 7 7 7 0 Ankyrin repeat DUF5049 PF16468.5 EGG18702.1 - 0.00089 19.1 0.1 34 4.4 0.0 5.2 4 1 1 5 5 5 0 Domain of unknown function (DUF5049) DUF4371 PF14291.6 EGG18702.1 - 0.038 13.6 0.1 0.093 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) Glyco_hydro_18 PF00704.28 EGG18703.1 - 1.4e-21 77.6 0.1 2e-21 77.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FBA_3 PF08268.12 EGG18703.1 - 0.073 13.0 0.1 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 F-box associated domain RicinB_lectin_2 PF14200.6 EGG18704.1 - 1.9e-08 34.9 12.6 0.00019 22.1 0.3 4.3 1 1 5 6 6 6 4 Ricin-type beta-trefoil lectin domain-like Lipoprotein_11 PF03260.13 EGG18704.1 - 0.0001 21.8 1.7 0.0001 21.8 1.7 2.1 1 1 1 2 2 2 1 Lepidopteran low molecular weight (30 kD) lipoprotein DUF2255 PF10012.9 EGG18705.1 - 0.061 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) Ank_5 PF13857.6 EGG18706.1 - 1.2e-08 35.1 5.0 0.0045 17.3 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG18706.1 - 1.1e-06 29.1 0.0 0.00016 22.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18706.1 - 1.1e-05 25.9 0.1 8.8e-05 23.0 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG18706.1 - 4.5e-05 23.5 0.0 0.62 10.8 0.0 3.9 2 1 1 3 3 3 1 Ankyrin repeat Adaptin_N PF01602.20 EGG18708.1 - 2.5e-143 478.4 13.7 3e-143 478.1 13.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EGG18708.1 - 3.2e-24 85.4 0.8 3.2e-24 85.4 0.8 2.3 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 EGG18708.1 - 9e-13 48.6 7.4 2.6e-08 34.1 0.1 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGG18708.1 - 4.5e-06 26.5 0.8 2.9 8.4 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EGG18708.1 - 3.4e-05 24.1 0.3 1.8 9.0 0.0 4.2 4 0 0 4 4 4 2 HEAT repeats TIP120 PF08623.10 EGG18708.1 - 4.6e-05 23.2 2.9 1.3 8.8 0.2 3.5 3 0 0 3 3 3 2 TATA-binding protein interacting (TIP20) NPCBM_assoc PF10633.9 EGG18708.1 - 0.095 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase V-ATPase_H_C PF11698.8 EGG18708.1 - 0.32 11.1 3.0 8.4 6.5 0.0 4.1 3 1 1 4 4 4 0 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 EGG18708.1 - 0.39 11.3 3.9 23 5.7 0.1 3.8 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region DUF1631 PF07793.11 EGG18708.1 - 0.49 8.8 7.0 0.7 8.2 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Npa1 PF11707.8 EGG18708.1 - 0.96 8.7 5.8 1.1 8.6 0.0 3.4 3 1 1 5 5 5 0 Ribosome 60S biogenesis N-terminal Y_phosphatase2 PF03162.13 EGG18709.1 - 1.3e-57 194.0 0.0 1.4e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGG18709.1 - 0.0061 16.6 0.0 0.015 15.3 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGG18709.1 - 0.24 10.9 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Myb_DNA-binding PF00249.31 EGG18710.1 - 4.8e-10 39.5 0.1 1e-09 38.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG18710.1 - 4.3e-05 23.7 0.1 0.00015 22.0 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGG18710.1 - 0.01 15.7 0.1 0.01 15.7 0.1 2.0 2 0 0 2 2 2 0 Myb DNA-binding like Longin PF13774.6 EGG18711.1 - 2.2e-21 75.7 2.4 4.3e-21 74.7 2.4 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain MaoC_dehydratas PF01575.19 EGG18711.1 - 1.6e-17 63.3 0.0 3.1e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain Synaptobrevin PF00957.21 EGG18711.1 - 4.6e-14 52.0 0.0 1.4e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Synaptobrevin MaoC_dehydrat_N PF13452.6 EGG18711.1 - 0.033 14.3 0.0 0.39 10.8 0.0 2.2 1 1 1 2 2 2 0 N-terminal half of MaoC dehydratase 4HBT PF03061.22 EGG18711.1 - 0.095 13.1 0.0 0.34 11.3 0.0 1.9 1 1 0 1 1 1 0 Thioesterase superfamily Methyltransf_10 PF05971.12 EGG18712.1 - 1.3e-63 215.1 0.7 1.4e-61 208.5 0.7 2.3 1 1 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EGG18712.1 - 5.5e-06 26.0 0.0 2.6e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGG18712.1 - 9.9e-05 21.9 0.0 0.00021 20.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EGG18712.1 - 0.0023 17.9 0.0 0.0055 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG18712.1 - 0.16 12.7 0.0 1.9 9.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain L_lactis_RepB_C PF06430.12 EGG18712.1 - 0.84 9.6 4.7 1.9 8.5 0.0 3.2 2 0 0 2 2 2 0 Lactococcus lactis RepB C-terminus TPR_1 PF00515.28 EGG18713.1 - 4.1e-15 54.9 8.3 2.7e-06 27.0 0.5 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG18713.1 - 3.9e-14 51.5 3.7 0.00011 22.1 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGG18713.1 - 1.3e-07 31.8 0.6 0.00026 21.2 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-C3HC4 PF00097.25 EGG18713.1 - 3e-07 30.2 15.5 8.3e-07 28.8 15.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG18713.1 - 1.2e-06 28.2 15.6 2.5e-06 27.2 15.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_17 PF13431.6 EGG18713.1 - 2.1e-06 27.7 0.7 0.0039 17.5 0.2 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat zf-RING_5 PF14634.6 EGG18713.1 - 3.1e-06 27.0 14.4 9.1e-06 25.5 14.4 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGG18713.1 - 4.6e-06 26.4 10.9 1.1e-05 25.2 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.6 EGG18713.1 - 5.3e-06 26.2 5.6 0.0066 16.6 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG18713.1 - 2.1e-05 24.6 3.2 2.1e-05 24.6 3.2 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGG18713.1 - 4.7e-05 23.8 0.0 0.00054 20.4 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 EGG18713.1 - 5.4e-05 22.3 0.4 0.00013 21.1 0.4 1.7 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 zf-RING_UBOX PF13445.6 EGG18713.1 - 0.00012 22.0 13.0 0.00045 20.2 13.1 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGG18713.1 - 0.00024 21.3 15.7 0.00061 20.1 15.7 1.7 1 0 0 1 1 1 1 Ring finger domain TPR_11 PF13414.6 EGG18713.1 - 0.00052 19.7 13.1 0.022 14.4 1.9 4.1 2 1 2 4 4 4 2 TPR repeat TPR_16 PF13432.6 EGG18713.1 - 0.00092 19.8 0.0 0.67 10.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 EGG18713.1 - 0.0025 17.9 17.0 0.0057 16.8 17.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGG18713.1 - 0.0046 16.8 9.2 0.0091 15.9 9.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein TPR_9 PF13371.6 EGG18713.1 - 0.01 15.9 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5588 PF17826.1 EGG18713.1 - 0.014 14.3 0.4 0.026 13.4 0.4 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5588) Mucin PF01456.17 EGG18713.1 - 0.036 14.1 14.5 0.076 13.0 14.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Prok-RING_4 PF14447.6 EGG18713.1 - 0.057 13.3 17.0 4.8 7.1 17.9 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TPR_6 PF13174.6 EGG18713.1 - 0.089 13.5 3.9 2.1 9.2 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 EGG18713.1 - 0.64 9.9 13.4 3.2 7.6 13.6 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-C2H2_12 PF18112.1 EGG18713.1 - 0.87 10.1 8.4 2.4 8.7 0.6 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain XRN_N PF03159.18 EGG18714.1 - 3.6e-35 121.6 0.0 2.3e-17 63.2 0.0 3.2 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EGG18714.1 - 0.0011 18.0 2.5 0.14 11.1 0.0 3.0 2 1 1 3 3 3 2 Xrn1 helical domain NmrA PF05368.13 EGG18715.1 - 2.1e-51 174.7 1.8 2.6e-51 174.5 1.8 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGG18715.1 - 2.2e-16 60.3 0.3 4.2e-16 59.4 0.2 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EGG18715.1 - 4.6e-05 23.0 0.1 9.3e-05 22.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGG18715.1 - 5e-05 23.6 0.8 0.00094 19.4 0.3 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EGG18715.1 - 0.0076 16.7 0.2 0.015 15.7 0.2 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EGG18715.1 - 0.059 13.5 0.2 0.77 9.9 0.0 2.3 1 1 2 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Ank_2 PF12796.7 EGG18716.1 - 3.6e-12 46.7 14.4 9.8e-05 22.9 1.9 6.2 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG18716.1 - 1.2e-07 31.5 5.0 26 5.8 0.0 8.5 9 0 0 9 9 9 1 Ankyrin repeat Ank_4 PF13637.6 EGG18716.1 - 1.8e-07 31.6 9.0 1.1 10.0 0.1 8.1 7 2 1 8 8 8 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18716.1 - 0.00031 21.0 0.5 4.6 7.7 0.0 5.6 5 1 0 5 5 5 1 Ankyrin repeats (many copies) Phage_T7_Capsid PF05396.11 EGG18716.1 - 0.55 10.6 1.7 36 4.7 0.0 3.5 3 1 1 4 4 4 0 Phage T7 capsid assembly protein DUF3447 PF11929.8 EGG18716.1 - 1.1 9.2 20.0 1.7 8.6 0.5 6.3 6 1 1 7 7 7 0 Domain of unknown function (DUF3447) GYF_2 PF14237.6 EGG18717.1 - 1.4e-14 53.6 0.1 1.2e-13 50.7 0.1 2.3 2 0 0 2 2 2 1 GYF domain 2 DnaJ PF00226.31 EGG18717.1 - 1.4e-13 50.8 0.4 4.5e-13 49.1 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain V-ATPase_H_N PF03224.14 EGG18717.1 - 0.38 10.0 3.9 0.53 9.5 1.9 2.3 2 0 0 2 2 2 0 V-ATPase subunit H RPN5_C PF18098.1 EGG18717.1 - 7 6.8 6.7 29 4.9 0.3 3.8 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN5 C-terminal domain Ank_2 PF12796.7 EGG18718.1 - 4.8e-96 315.5 15.0 2.3e-20 73.0 0.2 7.9 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18718.1 - 2.1e-82 270.5 13.8 2.1e-12 47.3 0.1 10.4 3 2 6 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 EGG18718.1 - 7.7e-79 257.0 35.2 1e-06 28.9 0.1 15.3 15 0 0 15 15 15 14 Ankyrin repeat Ank_3 PF13606.6 EGG18718.1 - 1.1e-76 243.6 14.6 0.00012 22.3 0.1 14.8 15 0 0 15 15 15 14 Ankyrin repeat Sec7 PF01369.20 EGG18718.1 - 1.8e-71 239.6 0.5 2.9e-71 238.9 0.5 1.3 1 0 0 1 1 1 1 Sec7 domain Ank_5 PF13857.6 EGG18718.1 - 8.1e-71 233.2 18.0 1.4e-10 41.2 0.2 12.9 1 1 11 13 13 13 13 Ankyrin repeats (many copies) PH PF00169.29 EGG18718.1 - 2.2e-25 89.2 0.3 4.7e-25 88.1 0.3 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGG18718.1 - 3.3e-07 30.7 0.5 1.5e-06 28.6 0.5 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 EGG18718.1 - 0.014 15.7 0.2 3.7 7.9 0.0 3.4 2 1 1 3 3 3 0 Pleckstrin homology domain Man-6-P_recep PF02157.15 EGG18719.1 - 1.2e-09 37.7 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EGG18719.1 - 2.2e-09 37.6 0.1 3.2e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 Ribosomal_L31e PF01198.19 EGG18720.1 - 3.2e-30 104.2 2.2 4.3e-30 103.8 2.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L31e DNase_II PF03265.15 EGG18721.1 - 4.3e-24 85.4 5.3 6.9e-19 68.3 1.0 3.2 3 0 0 3 3 3 3 Deoxyribonuclease II DNase_II PF03265.15 EGG18722.1 - 5e-16 58.9 9.3 1.6e-10 40.8 0.2 3.4 3 1 0 3 3 3 2 Deoxyribonuclease II DNase_II PF03265.15 EGG18723.1 - 1.2e-20 74.1 5.1 1.9e-16 60.2 1.5 3.2 3 0 0 3 3 3 3 Deoxyribonuclease II p450 PF00067.22 EGG18724.1 - 1.9e-70 237.9 0.2 3.2e-70 237.2 0.2 1.3 1 0 0 1 1 1 1 Cytochrome P450 Ank_4 PF13637.6 EGG18724.1 - 3.5e-22 78.5 3.5 0.00012 22.6 0.2 7.4 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18724.1 - 7.3e-22 77.8 10.8 0.00047 20.7 0.0 6.6 3 1 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18724.1 - 3.4e-16 59.1 6.0 0.0029 17.9 0.0 10.2 4 3 7 11 11 11 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18724.1 - 2.8e-10 39.5 1.4 21 6.1 0.0 10.8 11 1 1 12 12 12 1 Ankyrin repeat Ocular_alb PF02101.15 EGG18724.1 - 0.079 11.9 1.6 0.43 9.4 0.1 2.6 3 0 0 3 3 3 0 Ocular albinism type 1 protein Pan3_PK PF18101.1 EGG18725.1 - 2.6e-60 202.4 0.1 2.6e-60 202.4 0.1 2.5 3 0 0 3 3 3 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EGG18725.1 - 5.7e-11 42.3 0.2 1.7e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG18725.1 - 0.00018 20.9 2.1 0.0019 17.5 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Vac7 PF12751.7 EGG18725.1 - 0.82 9.0 11.4 1.2 8.5 11.4 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 PAT1 PF09770.9 EGG18725.1 - 8.9 4.4 27.7 13 3.9 27.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gaa1 PF04114.14 EGG18726.1 - 1.6e-44 152.8 2.2 1.6e-44 152.8 2.2 2.5 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component Oxidored_q3 PF00499.20 EGG18726.1 - 4.6 6.9 9.6 3.9 7.2 0.0 4.1 4 0 0 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Ank_4 PF13637.6 EGG18727.1 - 1.3e-27 95.8 2.1 4.7e-06 27.1 0.0 7.9 5 2 0 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18727.1 - 1.5e-26 92.8 6.5 9.2e-09 35.8 0.1 6.0 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18727.1 - 6.6e-25 86.9 0.4 0.0075 16.6 0.0 10.3 5 3 7 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18727.1 - 3.9e-17 60.6 0.2 10 7.1 0.0 10.8 11 0 0 11 11 11 1 Ankyrin repeat DUF5049 PF16468.5 EGG18727.1 - 9.7e-06 25.4 2.6 2.2 8.2 0.1 5.9 4 2 3 7 7 7 2 Domain of unknown function (DUF5049) Ank PF00023.30 EGG18727.1 - 0.013 15.9 0.0 2.8e+02 2.2 0.0 6.3 3 3 1 4 4 4 0 Ankyrin repeat Tom37 PF10568.9 EGG18727.1 - 0.014 15.7 0.1 7.1 7.0 0.0 3.5 3 2 0 3 3 3 0 Outer mitochondrial membrane transport complex protein HIGH_NTase1_ass PF16581.5 EGG18727.1 - 0.05 13.6 0.3 6.9 6.6 0.0 3.4 2 2 0 4 4 4 0 Cytidyltransferase-related C-terminal region Telomerase_RBD PF12009.8 EGG18727.1 - 0.18 11.9 0.8 1.8 8.7 0.0 2.6 3 0 0 3 3 3 0 Telomerase ribonucleoprotein complex - RNA binding domain Kazal_2 PF07648.15 EGG18728.1 - 0.027 14.6 0.5 0.094 12.9 0.5 1.9 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain DUF1035 PF06281.12 EGG18728.1 - 0.25 11.4 3.2 1 9.4 3.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) Pyr_redox_2 PF07992.14 EGG18729.1 - 1.8e-51 175.1 1.4 2.2e-51 174.9 1.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG18729.1 - 5.6e-18 65.3 1.4 1.1e-16 61.2 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG18729.1 - 1.4e-17 64.0 0.3 2.3e-15 56.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGG18729.1 - 2.4e-06 27.2 0.5 0.0037 16.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGG18729.1 - 0.00051 19.4 0.1 0.0016 17.8 0.1 1.7 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 EGG18729.1 - 0.0016 17.6 0.1 1 8.5 0.0 3.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 EGG18729.1 - 0.0071 16.8 0.2 0.11 13.0 0.1 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 EGG18729.1 - 0.014 14.1 0.4 0.63 8.7 0.3 2.3 1 1 1 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 EGG18729.1 - 0.067 12.3 3.8 0.79 8.7 0.6 2.8 2 1 1 3 3 3 0 FAD binding domain SIS_2 PF13580.6 EGG18729.1 - 0.1 12.6 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 SIS domain ER PF01133.17 EGG18730.1 - 4.1e-28 97.3 1.2 1.5e-26 92.3 1.2 2.0 1 1 0 1 1 1 1 Enhancer of rudimentary Pro_isomerase PF00160.21 EGG18731.1 - 5.3e-47 160.0 0.1 6.1e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.29 EGG18732.1 - 8e-45 152.7 0.0 1.7e-44 151.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG18732.1 - 1.6e-30 105.7 4.1 1.2e-29 102.9 0.1 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG18732.1 - 1.9e-11 44.2 0.0 1.9e-11 44.2 0.0 3.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit BUD22 PF09073.10 EGG18732.1 - 0.00013 21.4 37.7 0.00013 21.4 37.7 2.1 2 0 0 2 2 2 1 BUD22 AAA_22 PF13401.6 EGG18732.1 - 0.0086 16.4 0.0 0.031 14.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG18732.1 - 0.047 14.0 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Citrate_bind PF16114.5 EGG18733.1 - 1.2e-81 272.5 0.0 1.7e-81 272.0 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EGG18733.1 - 4.3e-16 59.1 0.0 8.7e-16 58.1 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain Cyclin_N PF00134.23 EGG18734.1 - 7.5e-10 38.6 0.2 1.2e-09 38.0 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Glyco_transf_10 PF00852.19 EGG18737.1 - 1.8e-34 119.0 1.2 5.7e-34 117.4 1.2 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Laminin_G_3 PF13385.6 EGG18737.1 - 4.1e-23 82.2 0.2 4.1e-23 82.2 0.2 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Sialidase PF02973.16 EGG18737.1 - 1.2e-05 24.9 0.4 3.2e-05 23.5 0.4 1.7 1 0 0 1 1 1 1 Sialidase, N-terminal domain ARA70 PF12489.8 EGG18737.1 - 0.6 10.3 17.7 0.044 14.0 4.9 3.4 3 0 0 3 3 3 0 Nuclear coactivator Spt20 PF12090.8 EGG18737.1 - 0.84 9.2 21.6 0.087 12.4 14.5 2.2 2 0 0 2 2 2 0 Spt20 family DUF1387 PF07139.11 EGG18737.1 - 2.4 7.8 14.7 0.078 12.7 6.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) EBP PF05241.12 EGG18738.1 - 6.4e-43 146.3 9.4 7.5e-43 146.0 9.4 1.1 1 0 0 1 1 1 1 Emopamil binding protein DUF3278 PF11683.8 EGG18738.1 - 1.3 9.1 7.1 1.7 8.7 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) NIF3 PF01784.18 EGG18739.1 - 1.2e-65 221.6 0.0 1.6e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RloB PF13707.6 EGG18739.1 - 0.083 13.1 0.0 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 RloB-like protein SLS PF14611.6 EGG18739.1 - 0.7 9.7 5.3 1.9 8.2 0.5 2.7 2 1 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator MutS_V PF00488.21 EGG18740.1 - 8.7e-83 277.0 0.4 1.6e-82 276.1 0.4 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGG18740.1 - 2.4e-31 109.5 3.9 1.5e-30 106.9 1.3 2.6 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EGG18740.1 - 1.4e-13 50.9 4.7 2e-13 50.5 0.9 2.7 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 EGG18740.1 - 7.7e-11 42.4 1.7 3.1e-10 40.4 0.1 2.5 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.20 EGG18740.1 - 1.1e-06 28.8 0.1 0.0036 17.5 0.1 2.6 2 0 0 2 2 2 2 MutS domain I AAA_27 PF13514.6 EGG18740.1 - 0.017 14.7 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AF2331-like PF14556.6 EGG18740.1 - 0.053 14.1 0.1 0.41 11.3 0.1 2.6 2 0 0 2 2 2 0 AF2331-like Put_DNA-bind_N PF06971.13 EGG18740.1 - 0.061 13.3 0.1 0.61 10.1 0.1 2.6 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus RsbU_N PF08673.10 EGG18740.1 - 0.068 13.3 1.0 12 6.1 0.3 3.1 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain WD40 PF00400.32 EGG18741.1 - 1.9e-45 151.9 24.9 2.6e-07 31.2 1.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG18741.1 - 3.6e-16 59.2 2.3 0.01 16.1 0.0 6.2 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG18741.1 - 2.6e-06 26.6 3.0 0.24 10.3 0.1 4.0 1 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EGG18741.1 - 0.001 17.5 0.2 0.2 10.0 0.0 3.1 2 1 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 EGG18741.1 - 0.011 14.4 4.3 0.89 8.1 2.8 3.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EGG18741.1 - 0.049 13.7 0.6 1.6 8.8 0.1 3.2 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EGG18741.1 - 0.29 10.4 8.4 4.8 6.4 0.1 3.7 1 1 0 2 2 2 0 WD40-like domain Spt20 PF12090.8 EGG18741.1 - 2 8.0 12.1 3.3 7.3 12.1 1.2 1 0 0 1 1 1 0 Spt20 family Myosin_head PF00063.21 EGG18742.1 - 1.4e-271 902.6 9.0 1.9e-271 902.2 9.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGG18742.1 - 9.4e-40 136.3 5.3 2e-39 135.2 5.3 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 EGG18742.1 - 7.3e-09 34.7 4.4 0.00023 20.7 0.0 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_18 PF13238.6 EGG18742.1 - 0.04 14.5 0.1 0.21 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGG18742.1 - 0.051 13.8 0.0 0.29 11.4 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG18742.1 - 0.059 13.7 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 EGG18742.1 - 0.14 11.7 0.4 6.5 6.2 0.1 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Transket_pyr PF02779.24 EGG18743.1 - 3.6e-49 166.8 0.0 6.3e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EGG18743.1 - 1.1e-48 165.8 0.0 2e-48 164.9 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EGG18743.1 - 2.7e-48 163.5 0.0 5.1e-48 162.6 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Cas6_N PF17952.1 EGG18743.1 - 0.027 14.7 0.4 0.17 12.1 0.0 2.6 2 0 0 2 2 2 0 Cas6 N-terminal domain DUF2721 PF11026.8 EGG18743.1 - 0.071 13.0 3.1 0.17 11.8 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) TraG_N PF07916.11 EGG18743.1 - 1.7 7.4 6.2 0.71 8.7 3.1 1.8 2 0 0 2 2 2 0 TraG-like protein, N-terminal region ABC2_membrane PF01061.24 EGG18744.1 - 1.1e-87 292.8 63.6 2.2e-45 154.6 28.8 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGG18744.1 - 7.9e-38 130.1 0.8 5e-19 69.2 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 EGG18744.1 - 1.2e-27 95.6 9.1 5.6e-23 80.7 0.0 4.2 4 0 0 4 4 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 EGG18744.1 - 2.9e-08 33.2 15.3 2.9e-08 33.2 15.3 3.5 4 1 0 4 4 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGG18744.1 - 4.5e-07 29.9 0.3 0.0001 22.3 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_trans_N PF14510.6 EGG18744.1 - 6e-07 30.0 1.4 1.9e-06 28.4 1.4 1.9 1 1 0 1 1 1 1 ABC-transporter N-terminal AAA_29 PF13555.6 EGG18744.1 - 3.4e-06 26.7 0.2 0.0059 16.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGG18744.1 - 9.1e-05 22.4 0.5 0.4 10.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGG18744.1 - 0.0005 20.5 0.0 0.44 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGG18744.1 - 0.0028 17.9 0.2 0.79 10.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGG18744.1 - 0.0038 17.0 0.2 2.6 7.7 0.6 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGG18744.1 - 0.0045 16.6 0.1 0.012 15.2 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGG18744.1 - 0.0051 17.0 0.0 0.86 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGG18744.1 - 0.0093 15.3 0.0 2.4 7.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 EGG18744.1 - 0.023 15.3 2.1 0.72 10.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 EGG18744.1 - 0.026 14.6 0.1 13 5.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 EGG18744.1 - 0.033 13.8 0.1 0.77 9.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EGG18744.1 - 0.07 13.0 0.3 3.7 7.4 0.3 2.4 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 EGG18744.1 - 0.096 13.1 0.1 7.8 6.9 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGG18744.1 - 0.52 10.5 2.3 0.88 9.8 0.3 2.4 3 0 0 3 3 3 0 AAA domain SAM_decarbox PF01536.16 EGG18745.1 - 1.7e-101 339.8 0.0 2e-101 339.5 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Pkinase PF00069.25 EGG18746.1 - 8.6e-78 261.3 0.0 1.7e-77 260.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG18746.1 - 1.1e-36 126.4 0.0 1.7e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCHH PF10283.9 EGG18746.1 - 5.1e-13 48.8 2.3 1e-12 47.8 2.3 1.5 1 0 0 1 1 1 1 PBZ domain FHA PF00498.26 EGG18746.1 - 1.5e-12 47.6 0.2 4.2e-12 46.2 0.2 1.8 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 EGG18746.1 - 7.5e-10 38.5 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGG18746.1 - 2.5e-08 33.6 0.0 7e-08 32.1 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGG18746.1 - 0.00016 20.6 0.0 0.00016 20.6 0.0 3.0 3 1 0 3 3 3 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 EGG18746.1 - 0.00042 20.6 0.0 0.0014 18.9 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RIO1 PF01163.22 EGG18746.1 - 0.0044 16.6 0.4 0.01 15.4 0.4 1.6 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EGG18746.1 - 0.061 12.9 0.2 0.24 11.0 0.1 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Hid1 PF12722.7 EGG18747.1 - 1.5e-133 446.8 44.2 2.2e-131 439.6 44.2 3.1 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EGG18747.1 - 6.9e-130 434.4 20.5 8.9e-130 434.0 20.5 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF913 PF06025.12 EGG18747.1 - 0.00036 19.6 16.7 0.0071 15.4 10.2 2.7 2 1 0 2 2 2 2 Domain of Unknown Function (DUF913) DUF4770 PF15994.5 EGG18747.1 - 0.0004 20.7 1.4 0.0004 20.7 1.4 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4770) Spt20 PF12090.8 EGG18747.1 - 0.0028 17.3 20.3 0.0028 17.3 20.3 3.4 2 1 0 2 2 1 1 Spt20 family TFIIA PF03153.13 EGG18747.1 - 0.013 15.6 13.8 0.013 15.6 13.8 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 EGG18747.1 - 0.043 14.2 0.6 0.043 14.2 0.6 3.2 2 1 0 2 2 1 0 Enhancer of polycomb-like DUF2722 PF10846.8 EGG18747.1 - 0.16 10.9 42.2 0.72 8.7 11.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RP-C_C PF11800.8 EGG18747.1 - 0.33 11.0 16.6 0.53 10.3 6.8 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region Suf PF05843.14 EGG18747.1 - 0.4 10.6 25.7 0.34 10.9 5.0 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) MecA PF05389.12 EGG18747.1 - 0.44 10.2 9.3 1.7 8.2 0.6 2.6 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) ASD2 PF08687.11 EGG18747.1 - 0.45 10.0 18.8 1.2 8.6 1.3 2.3 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 MMR1 PF08505.10 EGG18747.1 - 0.6 10.3 31.0 0.34 11.2 6.3 2.5 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein SpoIIP PF07454.11 EGG18747.1 - 0.82 9.1 17.2 0.1 12.1 1.0 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Neur_chan_memb PF02932.16 EGG18747.1 - 0.86 9.6 10.6 3.1 7.8 0.6 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 EGG18747.1 - 1.1 7.9 23.2 0.31 9.8 2.5 2.5 2 0 0 2 2 2 0 Presenilin Tim54 PF11711.8 EGG18747.1 - 1.6 7.4 18.6 0.2 10.4 3.6 2.5 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 DUF572 PF04502.13 EGG18747.1 - 1.7 8.2 20.4 3.4 7.2 2.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) FAM60A PF15396.6 EGG18747.1 - 1.7 8.6 14.8 6.1 6.8 1.6 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Endostatin PF06482.11 EGG18747.1 - 2.1 7.7 18.4 2.8 7.3 6.8 2.3 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin NUSAP PF16006.5 EGG18747.1 - 5 6.8 23.8 0.033 14.0 10.7 2.2 2 0 0 2 2 2 0 Nucleolar and spindle-associated protein Ndc1_Nup PF09531.10 EGG18747.1 - 6.2 5.4 25.7 5.1 5.6 6.7 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup TCP PF03634.13 EGG18747.1 - 6.7 7.3 20.2 2.5 8.7 0.7 2.4 2 0 0 2 2 2 0 TCP family transcription factor DUF1387 PF07139.11 EGG18747.1 - 7 6.3 25.2 2.9 7.5 4.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) PAT1 PF09770.9 EGG18747.1 - 7.1 4.8 29.7 0.45 8.7 7.9 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Mito_carr PF00153.27 EGG18749.1 - 1.9e-70 232.9 2.9 6e-29 99.8 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein PBECR3 PF18812.1 EGG18749.1 - 0.022 14.7 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 DUF588 PF04535.12 EGG18749.1 - 0.073 12.8 0.2 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF588) Paf1 PF03985.13 EGG18750.1 - 1.1e-48 166.4 19.0 3.1e-30 105.5 2.5 2.7 2 1 0 2 2 2 2 Paf1 FHA PF00498.26 EGG18751.1 - 2.4e-19 69.5 0.1 5.4e-19 68.3 0.1 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGG18751.1 - 1e-08 35.4 0.0 2.5e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Ribosomal_L7Ae PF01248.26 EGG18752.1 - 2e-21 75.5 0.0 2.4e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 EGG18752.1 - 0.054 13.6 0.0 0.08 13.1 0.0 1.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ank_4 PF13637.6 EGG18753.1 - 4e-33 113.4 2.4 7.9e-14 51.8 0.1 4.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG18753.1 - 4.6e-30 104.1 2.4 1.3e-16 60.9 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG18753.1 - 9.4e-21 71.7 4.4 2.9e-06 27.2 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EGG18753.1 - 4e-20 71.3 1.4 2.6e-05 24.5 0.2 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EGG18753.1 - 1.8e-16 60.0 2.5 7.5e-11 42.1 0.2 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Arm PF00514.23 EGG18754.1 - 6.5e-23 80.0 33.4 0.028 14.5 0.2 16.2 17 0 0 17 17 17 7 Armadillo/beta-catenin-like repeat WW PF00397.26 EGG18754.1 - 1.2e-17 63.6 3.5 4.9e-10 39.3 0.2 2.5 2 0 0 2 2 2 2 WW domain FYVE PF01363.21 EGG18754.1 - 2.6e-15 56.3 10.9 9.7e-15 54.5 10.9 2.1 1 0 0 1 1 1 1 FYVE zinc finger HEAT_2 PF13646.6 EGG18754.1 - 9.3e-09 35.6 0.7 0.88 10.0 0.0 6.5 6 0 0 6 6 6 2 HEAT repeats HEAT PF02985.22 EGG18754.1 - 0.0021 18.2 3.0 11 6.6 0.0 6.7 6 0 0 6 6 6 1 HEAT repeat Atx10homo_assoc PF09759.9 EGG18754.1 - 0.0051 16.8 8.6 11 6.1 0.0 6.7 6 0 0 6 6 6 2 Spinocerebellar ataxia type 10 protein domain ILVD_EDD PF00920.21 EGG18754.1 - 0.057 12.0 0.1 0.64 8.6 0.0 2.6 4 0 0 4 4 4 0 Dehydratase family V-ATPase_H_C PF11698.8 EGG18754.1 - 0.064 13.4 0.0 0.064 13.4 0.0 9.0 9 2 2 11 11 11 0 V-ATPase subunit H HEAT_EZ PF13513.6 EGG18754.1 - 0.41 11.2 6.1 18 6.0 0.1 5.2 3 2 2 5 5 5 0 HEAT-like repeat CAF1 PF04857.20 EGG18755.1 - 4.9e-47 160.7 8.1 7.9e-47 160.0 8.1 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease zf-CCCH PF00642.24 EGG18755.1 - 3.3e-06 26.8 1.2 5.8e-06 26.1 1.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGG18755.1 - 0.00051 20.0 4.6 0.00098 19.1 4.6 1.5 1 0 0 1 1 1 1 Zinc finger domain Spy1 PF11357.8 EGG18756.1 - 4.1e-08 33.6 1.0 1.2e-05 25.6 1.0 2.5 1 1 0 1 1 1 1 Cell cycle regulatory protein Presenilin PF01080.17 EGG18756.1 - 0.14 10.9 5.1 0.16 10.7 5.1 1.2 1 0 0 1 1 1 0 Presenilin Sugar_transport PF06800.12 EGG18756.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Sugar transport protein Membralin PF09746.9 EGG18756.1 - 0.79 8.7 9.0 1.1 8.2 9.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein SLC12 PF03522.15 EGG18756.1 - 2.5 7.0 18.4 4.5 6.2 18.4 1.4 1 0 0 1 1 1 0 Solute carrier family 12 BCL_N PF04714.13 EGG18757.1 - 0.0026 17.8 1.8 0.007 16.4 1.8 1.7 1 0 0 1 1 1 1 BCL7, N-terminal conserver region DUF3439 PF11921.8 EGG18757.1 - 0.02 14.9 19.0 0.02 14.9 19.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3439) Androgen_recep PF02166.16 EGG18757.1 - 0.14 10.9 18.8 0.23 10.3 18.8 1.4 1 0 0 1 1 1 0 Androgen receptor DUF2207 PF09972.9 EGG18757.1 - 2.8 6.6 11.2 0.33 9.6 6.1 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MscS_TM PF12794.7 EGG18757.1 - 4.5 6.0 9.0 8.7 5.1 9.0 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Macoilin PF09726.9 EGG18757.1 - 5.2 5.5 33.9 7 5.1 33.9 1.3 1 0 0 1 1 1 0 Macoilin family NOA36 PF06524.12 EGG18757.1 - 5.5 6.2 18.4 3.2 7.0 10.0 2.2 2 0 0 2 2 2 0 NOA36 protein FYDLN_acid PF09538.10 EGG18757.1 - 5.6 7.7 25.5 2.5 8.8 6.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) RabGAP-TBC PF00566.18 EGG18758.1 - 1.5e-55 188.2 3.5 1.5e-55 188.2 3.5 3.4 4 0 0 4 4 4 1 Rab-GTPase-TBC domain 2OG-FeII_Oxy_5 PF13759.6 EGG18758.1 - 1.1 9.7 5.0 0.67 10.4 1.4 2.5 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase MIOX PF05153.15 EGG18759.1 - 3.6e-98 328.1 7.1 5.5e-71 239.1 0.1 2.4 1 1 1 2 2 2 2 Myo-inositol oxygenase GAT PF03127.14 EGG18759.1 - 1.1e-10 41.7 1.7 4.1e-10 39.8 0.5 2.5 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 EGG18759.1 - 4.2e-09 36.4 0.1 1.2e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 VHS domain PAT1 PF09770.9 EGG18759.1 - 0.026 12.8 38.2 0.055 11.7 38.2 1.6 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HD PF01966.22 EGG18759.1 - 0.24 11.6 0.0 0.69 10.1 0.0 1.7 1 0 0 1 1 1 0 HD domain Pkinase PF00069.25 EGG18760.1 - 1.7e-74 250.5 0.0 2.7e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG18760.1 - 1.6e-35 122.7 0.0 2.3e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGG18760.1 - 9.1e-07 29.5 0.7 9.1e-07 29.5 0.7 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGG18760.1 - 0.00015 21.2 0.0 0.0012 18.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGG18760.1 - 0.00069 18.5 5.4 0.0023 16.8 5.4 1.8 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGG18760.1 - 0.0025 17.5 3.3 0.24 11.0 0.0 2.8 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGG18760.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG18760.1 - 0.02 13.9 1.8 0.037 13.0 1.8 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EGG18760.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5523 PF17661.1 EGG18760.1 - 0.5 10.0 11.9 0.79 9.4 11.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF4699 PF15770.5 EGG18760.1 - 1.9 8.2 19.4 2.7 7.7 19.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) DUF3439 PF11921.8 EGG18760.1 - 2.2 8.3 8.6 6 6.9 8.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ndc1_Nup PF09531.10 EGG18760.1 - 4.9 5.7 8.1 6.2 5.4 8.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.16 EGG18761.1 - 7.7e-29 100.7 71.5 4.2e-20 72.0 45.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGG18761.1 - 5.4e-11 41.7 30.8 1.7e-09 36.8 27.7 3.5 2 1 0 2 2 2 1 MFS/sugar transport protein BT1 PF03092.16 EGG18761.1 - 1.2e-05 23.8 10.4 0.00071 17.9 1.6 2.9 3 0 0 3 3 3 2 BT1 family PUCC PF03209.15 EGG18761.1 - 1.7e-05 24.1 19.9 0.0013 17.8 6.3 2.8 2 1 0 2 2 2 2 PUCC protein DUF4834 PF16118.5 EGG18761.1 - 0.02 15.8 0.1 0.02 15.8 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) DUF4169 PF13770.6 EGG18761.1 - 0.1 12.9 1.6 0.16 12.3 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) Ribosomal_L30 PF00327.20 EGG18762.1 - 3.1e-12 46.2 0.0 6.7e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Polyoma_lg_T_C PF06431.11 EGG18762.1 - 0.12 11.2 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus WD40 PF00400.32 EGG18763.1 - 3.9e-49 163.6 25.2 5.1e-09 36.6 0.3 8.9 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG18763.1 - 3.3e-27 94.6 3.2 1.2e-05 25.5 0.0 7.4 3 2 4 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG18763.1 - 1.2e-07 31.4 0.1 0.11 11.7 0.0 3.5 3 1 0 3 3 3 3 WD40-like domain eIF2A PF08662.11 EGG18763.1 - 3.5e-07 30.3 2.6 0.0029 17.5 0.3 4.1 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A SR-25 PF10500.9 EGG18763.1 - 0.00026 20.7 19.6 0.00043 20.0 19.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein LisH PF08513.11 EGG18763.1 - 0.01 15.8 3.7 0.18 11.8 0.3 2.8 2 0 0 2 2 2 0 LisH HGTP_anticodon2 PF12745.7 EGG18763.1 - 0.047 13.2 6.9 0.093 12.2 6.9 1.4 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Endostatin PF06482.11 EGG18763.1 - 0.069 12.6 3.2 0.12 11.8 3.2 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SWI-SNF_Ssr4 PF08549.10 EGG18763.1 - 0.12 11.0 3.8 0.16 10.6 3.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF1497 PF07384.11 EGG18763.1 - 0.23 11.9 3.8 0.52 10.8 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) Macoilin PF09726.9 EGG18763.1 - 0.25 9.8 8.0 0.33 9.5 8.0 1.1 1 0 0 1 1 1 0 Macoilin family Coilin_N PF15862.5 EGG18763.1 - 1 9.2 11.8 1.9 8.3 11.8 1.4 1 0 0 1 1 1 0 Coilin N-terminus NPR3 PF03666.13 EGG18763.1 - 3.2 6.4 11.7 4.7 5.9 11.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.16 EGG18763.1 - 5.9 6.3 7.0 10 5.6 7.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 SAC3_GANP PF03399.16 EGG18764.1 - 2.5e-21 76.3 10.6 2.5e-21 76.3 10.6 3.7 3 1 0 3 3 3 1 SAC3/GANP family IPP-2 PF04979.14 EGG18765.1 - 4.8e-19 69.4 26.5 4.8e-19 69.4 26.5 3.1 2 2 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) FPRL1_inhibitor PF16104.5 EGG18766.1 - 0.055 13.6 1.3 0.25 11.5 0.4 2.2 1 1 1 2 2 2 0 Formyl peptide receptor-like 1 inhibitory protein RGS PF00615.19 EGG18767.1 - 5.7e-41 139.5 11.8 5.8e-17 62.1 0.2 4.8 5 0 0 5 5 5 3 Regulator of G protein signaling domain RGS-like PF09128.11 EGG18767.1 - 3.3e-05 23.7 7.2 0.042 13.6 0.0 3.6 4 0 0 4 4 4 2 Regulator of G protein signalling-like domain DUF4922 PF16269.5 EGG18767.1 - 0.11 12.3 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) MAT1 PF06391.13 EGG18768.1 - 8e-26 91.1 46.9 1.5e-25 90.2 42.6 2.1 1 1 1 2 2 2 1 CDK-activating kinase assembly factor MAT1 Neisseria_TspB PF05616.13 EGG18768.1 - 0.002 16.7 0.7 0.0031 16.1 0.7 1.2 1 0 0 1 1 1 1 Neisseria meningitidis TspB protein zf-C3HC4 PF00097.25 EGG18768.1 - 0.013 15.3 3.1 0.033 14.0 3.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG18768.1 - 0.017 14.9 3.2 0.03 14.2 3.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG18768.1 - 0.046 13.7 1.5 0.11 12.5 1.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger EF-hand_5 PF13202.6 EGG18768.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 EF hand zf-C3HC4_4 PF15227.6 EGG18768.1 - 0.15 12.2 3.6 0.34 11.1 3.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGG18768.1 - 0.31 11.0 3.8 0.61 10.1 3.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Ank_2 PF12796.7 EGG18769.1 - 0.029 15.0 0.7 0.77 10.4 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18769.1 - 0.13 12.6 0.0 52 4.3 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.25 EGG18770.1 - 2.2e-06 27.9 0.0 2.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG18770.1 - 0.0044 17.4 0.1 0.0054 17.1 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG18770.1 - 0.0052 16.7 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain WD40 PF00400.32 EGG18771.1 - 2.4e-24 85.1 26.6 2.6e-07 31.2 0.1 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Bromodomain PF00439.25 EGG18771.1 - 9.8e-16 57.6 0.3 3e-15 56.1 0.3 1.9 1 0 0 1 1 1 1 Bromodomain Auxin_resp PF06507.13 EGG18771.1 - 1.3e-06 28.5 0.0 4.3e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Auxin response factor ANAPC4_WD40 PF12894.7 EGG18771.1 - 5.4e-06 26.6 0.5 1.7 9.0 0.2 4.7 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG18771.1 - 0.03 13.3 0.4 5 6.0 0.0 3.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GPI2 PF06432.11 EGG18772.1 - 0.002 17.7 1.2 0.0024 17.4 1.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase TFIIA PF03153.13 EGG18772.1 - 0.018 15.1 14.4 0.021 14.8 14.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MCU PF04678.13 EGG18772.1 - 0.033 14.3 2.7 0.042 13.9 2.7 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter BAF1_ABF1 PF04684.13 EGG18772.1 - 0.039 13.0 22.4 0.05 12.7 22.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DC_STAMP PF07782.13 EGG18772.1 - 0.084 12.7 1.4 0.17 11.7 1.4 1.5 1 0 0 1 1 1 0 DC-STAMP-like protein SKG6 PF08693.10 EGG18772.1 - 0.97 8.9 3.8 3 7.3 3.8 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Androgen_recep PF02166.16 EGG18772.1 - 1.3 7.8 3.9 1.7 7.4 3.9 1.2 1 0 0 1 1 1 0 Androgen receptor Suf PF05843.14 EGG18772.1 - 1.3 9.0 11.4 1.7 8.6 11.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.8 EGG18772.1 - 1.5 7.7 18.3 2.4 7.0 18.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Prefoldin PF02996.17 EGG18773.1 - 7.2e-12 45.3 2.4 5e-08 32.9 0.1 2.4 2 0 0 2 2 2 2 Prefoldin subunit KH_8 PF17903.1 EGG18774.1 - 8.1e-29 99.5 0.1 2.8e-28 97.8 0.1 2.0 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EGG18774.1 - 0.0066 16.2 0.1 0.065 13.1 0.0 2.6 2 1 1 3 3 3 1 KH domain GNT-I PF03071.15 EGG18775.1 - 3.3e-08 32.7 2.7 5.9e-08 31.9 1.4 1.8 1 1 1 2 2 2 1 GNT-I family PhaC_N PF07167.13 EGG18776.1 - 0.17 11.5 0.0 0.17 11.5 0.0 1.0 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Acetyltransf_9 PF13527.7 EGG18777.1 - 3.9e-09 36.6 0.0 5.4e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG18777.1 - 1.2e-05 25.5 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Mn_catalase PF05067.12 EGG18777.1 - 0.011 14.7 0.0 0.026 13.5 0.0 1.6 1 1 0 1 1 1 0 Manganese containing catalase Acetyltransf_7 PF13508.7 EGG18777.1 - 0.049 14.1 0.0 0.094 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RabGAP-TBC PF00566.18 EGG18778.1 - 1.2e-16 61.0 0.2 1.2e-16 61.0 0.2 3.5 3 1 0 3 3 3 1 Rab-GTPase-TBC domain EF-hand_1 PF00036.32 EGG18778.1 - 1.1e-12 46.5 2.3 1.1e-05 24.6 0.2 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGG18778.1 - 4.7e-12 44.8 3.1 2.9e-05 23.7 0.2 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGG18778.1 - 4.3e-11 43.1 5.6 5.6e-05 23.5 1.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG18778.1 - 5.9e-09 35.0 2.5 0.0023 17.3 0.3 3.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGG18778.1 - 0.00038 20.2 7.3 0.46 10.4 0.1 3.7 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 EGG18778.1 - 0.018 15.3 0.0 0.051 13.9 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Caleosin PF05042.13 EGG18778.1 - 0.073 13.0 0.1 13 5.7 0.0 2.8 1 1 1 2 2 2 0 Caleosin related protein Plk4_PB1 PF18190.1 EGG18778.1 - 0.086 13.0 0.1 0.31 11.2 0.1 2.0 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 PI3Ka PF00613.20 EGG18779.1 - 6.2e-21 74.6 5.8 1.1e-19 70.5 1.6 3.1 2 1 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGG18779.1 - 2e-18 67.1 9.7 2e-18 67.1 9.7 3.3 2 2 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 EGG18779.1 - 8.2e-16 57.9 10.3 8.2e-16 57.9 10.3 2.0 2 0 0 2 2 2 1 FYVE zinc finger DUF4135 PF13575.6 EGG18779.1 - 0.00013 21.4 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Hydrolase_4 PF12146.8 EGG18780.1 - 4.8e-06 26.0 0.0 8.4e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG18780.1 - 0.00042 20.0 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG18780.1 - 0.0079 16.8 0.0 0.012 16.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGG18780.1 - 0.08 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein UQ_con PF00179.26 EGG18781.1 - 2.1e-53 179.7 0.1 2.4e-53 179.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nucleoporin_FG PF13634.6 EGG18782.1 - 6.7e-23 81.4 159.6 1.5e-09 38.6 33.0 6.1 2 2 4 6 6 6 5 Nucleoporin FG repeat region Baculo_PEP_C PF04513.12 EGG18782.1 - 0.0017 18.4 6.9 0.021 14.9 1.0 2.2 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 EGG18782.1 - 0.0048 17.2 2.8 0.0048 17.2 2.8 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF5082) RPW8 PF05659.11 EGG18782.1 - 0.0064 16.2 3.5 0.3 10.8 0.3 2.3 2 0 0 2 2 2 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 Vip3A_N PF12495.8 EGG18782.1 - 0.014 15.3 0.7 0.03 14.2 0.7 1.5 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Fzo_mitofusin PF04799.13 EGG18782.1 - 0.031 13.8 3.8 0.11 12.1 0.3 2.3 2 0 0 2 2 2 0 fzo-like conserved region NPV_P10 PF05531.12 EGG18782.1 - 0.07 13.6 4.9 0.11 13.0 1.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ALMT PF11744.8 EGG18782.1 - 0.072 11.9 3.5 0.11 11.3 3.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1664 PF07889.12 EGG18782.1 - 0.11 12.6 1.5 5.2 7.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 EGG18782.1 - 0.11 12.9 9.3 0.063 13.7 1.3 2.4 2 0 0 2 2 2 0 Syntaxin-like protein LPP PF04728.13 EGG18782.1 - 0.12 12.7 2.2 4.8 7.7 0.3 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Translin PF01997.16 EGG18782.1 - 0.35 10.8 5.4 0.71 9.8 1.3 2.1 2 0 0 2 2 2 0 Translin family OmpH PF03938.14 EGG18782.1 - 0.43 10.9 6.6 0.9 9.9 2.4 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Tup_N PF08581.10 EGG18782.1 - 0.62 10.4 7.1 0.08 13.3 0.6 2.6 3 0 0 3 3 3 0 Tup N-terminal GAT PF03127.14 EGG18782.1 - 0.69 10.3 7.1 8.5 6.8 0.2 2.7 2 1 0 2 2 2 0 GAT domain APG17 PF04108.12 EGG18782.1 - 0.79 8.8 12.5 1 8.4 2.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 Jnk-SapK_ap_N PF09744.9 EGG18782.1 - 1 9.6 7.1 13 5.9 2.4 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 YkyA PF10368.9 EGG18782.1 - 2 8.1 11.8 0.17 11.6 2.2 2.4 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein Snapin_Pallidin PF14712.6 EGG18782.1 - 2.1 8.9 8.7 0.29 11.6 0.8 2.5 2 1 0 2 2 2 0 Snapin/Pallidin BLOC1_2 PF10046.9 EGG18782.1 - 5.3 7.4 9.6 1.2 9.4 2.0 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PCRF PF03462.18 EGG18783.1 - 5.1e-54 183.1 2.5 8e-54 182.4 1.1 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EGG18783.1 - 1.3e-38 131.5 2.4 1.3e-38 131.5 2.4 2.7 3 0 0 3 3 3 1 RF-1 domain DUF3439 PF11921.8 EGG18783.1 - 1.2 9.1 6.2 0.53 10.3 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) EF-hand_1 PF00036.32 EGG18784.1 - 2.1e-23 80.0 8.0 5.9e-05 22.3 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGG18784.1 - 4.7e-19 66.6 8.5 0.00021 21.0 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGG18784.1 - 6.3e-18 65.0 12.1 1e-08 35.5 1.9 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGG18784.1 - 7.3e-14 50.5 5.1 0.00092 18.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGG18784.1 - 3.5e-12 46.0 1.7 0.00035 20.4 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGG18784.1 - 1.3e-05 25.4 2.4 0.01 16.2 0.2 3.1 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_13 PF17958.1 EGG18784.1 - 6.7e-05 22.6 0.1 0.39 10.5 0.0 3.1 3 1 0 3 3 3 2 EF-hand domain Caleosin PF05042.13 EGG18784.1 - 0.00052 20.0 2.6 0.17 11.8 2.6 2.9 1 1 0 1 1 1 1 Caleosin related protein EF-hand_9 PF14658.6 EGG18784.1 - 0.031 14.6 0.0 25 5.3 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.6 EGG18784.1 - 0.034 14.0 2.3 11 6.0 0.1 3.4 2 2 2 4 4 3 0 EF hand Sigma70_r1_1 PF03979.14 EGG18784.1 - 0.036 14.1 0.4 2.9 8.0 0.2 2.4 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Dockerin_1 PF00404.18 EGG18784.1 - 0.038 14.2 0.4 14 6.0 0.0 2.8 3 0 0 3 3 3 0 Dockerin type I domain DUF3644 PF12358.8 EGG18784.1 - 0.077 13.5 2.0 5.8 7.5 0.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3644) DUF1636 PF07845.11 EGG18784.1 - 0.11 13.0 0.0 11 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1636) DUF3970 PF13113.6 EGG18784.1 - 2.4 8.5 5.4 0.8 10.0 1.6 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3970) AMP-binding PF00501.28 EGG18785.1 - 1e-57 195.7 0.0 1.4e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGG18785.1 - 3.6e-52 177.1 0.0 5.3e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EGG18785.1 - 5e-05 23.6 0.1 0.00015 22.0 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Glu_dehyd_C PF16912.5 EGG18785.1 - 0.095 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DUF4615 PF15393.6 EGG18786.1 - 1.3e-07 32.3 2.7 1.3e-07 32.3 2.7 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4615) NARP1 PF12569.8 EGG18786.1 - 0.029 13.3 6.0 0.042 12.8 6.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 UPF0556 PF10572.9 EGG18787.1 - 4.6e-09 35.9 0.0 5.3e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 CBS PF00571.28 EGG18788.1 - 8e-22 77.4 5.3 2.1e-06 28.1 0.0 4.5 4 1 1 5 5 5 4 CBS domain SDP_N PF12278.8 EGG18788.1 - 0.0069 16.5 2.2 0.014 15.6 2.2 1.4 1 0 0 1 1 1 1 Sex determination protein N terminal LON_substr_bdg PF02190.16 EGG18788.1 - 0.022 14.7 1.1 4.9 7.0 0.2 2.4 2 0 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain PglZ PF08665.12 EGG18788.1 - 0.048 13.7 0.9 0.11 12.6 0.9 1.6 1 0 0 1 1 1 0 PglZ domain DUF4355 PF14265.6 EGG18788.1 - 0.061 13.6 1.7 0.087 13.1 0.6 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) Transglut_core PF01841.19 EGG18789.1 - 5.8e-13 49.3 0.0 1e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily VMR2 PF17055.5 EGG18789.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Viral matrix protein M2 Arf PF00025.21 EGG18791.1 - 1.9e-63 213.1 0.0 2.4e-40 137.9 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGG18791.1 - 2.8e-10 40.5 0.0 6.7e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGG18791.1 - 6e-10 38.8 0.8 2.1e-05 23.9 0.1 2.9 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGG18791.1 - 1.5e-07 31.1 0.1 2.8e-06 26.9 0.1 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGG18791.1 - 6.1e-06 25.9 0.0 1.7e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGG18791.1 - 0.029 14.4 0.0 0.54 10.4 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGG18791.1 - 0.14 11.5 0.0 0.73 9.1 0.0 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF3439 PF11921.8 EGG18792.1 - 0.048 13.6 5.5 0.22 11.5 5.5 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGG18792.1 - 0.084 11.1 4.0 0.13 10.4 4.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SDA1 PF05285.12 EGG18793.1 - 5.7e-57 193.7 146.4 1.5e-31 110.1 58.0 4.9 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 EGG18793.1 - 1.4e-20 73.3 0.2 2.9e-20 72.3 0.2 1.6 1 0 0 1 1 1 1 NUC130/3NT domain SAM_3 PF18016.1 EGG18794.1 - 0.13 12.0 0.1 0.61 9.9 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) RPN6_C_helix PF18503.1 EGG18794.1 - 0.41 10.4 2.1 11 5.8 0.3 2.6 2 0 0 2 2 2 0 26S proteasome subunit RPN6 C-terminal helix domain TP_methylase PF00590.20 EGG18795.1 - 3.2e-21 76.3 0.0 6.2e-21 75.3 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Cpn60_TCP1 PF00118.24 EGG18796.1 - 5.2e-151 503.6 6.0 5.9e-151 503.4 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PucR PF07905.11 EGG18796.1 - 0.00021 21.6 0.0 0.00043 20.6 0.0 1.5 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family DUF356 PF04009.12 EGG18796.1 - 0.022 15.0 0.0 0.37 11.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF356) PrpR_N PF06506.11 EGG18796.1 - 0.097 12.2 2.1 0.14 11.7 0.2 2.2 3 0 0 3 3 3 0 Propionate catabolism activator DUF956 PF06115.11 EGG18796.1 - 0.13 12.0 0.2 3.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF956) DUF4507 PF14964.6 EGG18797.1 - 0.0074 15.3 0.4 0.014 14.3 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4507) DUF3798 PF12683.7 EGG18797.1 - 0.031 13.7 0.1 0.058 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) TPR_1 PF00515.28 EGG18798.1 - 1.1e-17 63.0 1.2 1.8e-07 30.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 EGG18798.1 - 3.2e-16 58.9 1.2 3.2e-16 58.9 1.2 1.9 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_8 PF13181.6 EGG18798.1 - 6.9e-16 57.1 0.8 7.5e-07 28.9 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG18798.1 - 9.7e-16 56.6 0.5 1.6e-06 27.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGG18798.1 - 5.2e-11 42.1 4.9 0.0011 18.6 1.1 3.4 1 1 2 3 3 3 3 TPR repeat TPR_17 PF13431.6 EGG18798.1 - 2.1e-09 37.1 2.5 0.0017 18.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG18798.1 - 1.1e-08 35.5 0.1 6.6e-05 23.5 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG18798.1 - 9.4e-08 32.3 0.0 0.0025 18.5 0.0 3.7 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG18798.1 - 1.4e-05 24.8 0.1 0.065 13.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG18798.1 - 1.6e-05 25.2 0.7 0.024 15.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG18798.1 - 2.3e-05 24.8 1.5 0.0039 17.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 EGG18798.1 - 6.6e-05 23.0 1.7 0.0011 19.1 0.3 3.1 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_12 PF13424.6 EGG18798.1 - 0.00012 22.3 0.1 0.012 15.9 0.0 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TOM20_plant PF06552.12 EGG18798.1 - 0.00092 19.0 1.0 0.13 12.0 0.0 3.1 2 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 ANAPC5 PF12862.7 EGG18798.1 - 0.066 13.3 1.4 0.24 11.5 0.3 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_15 PF13429.6 EGG18798.1 - 0.09 12.0 0.3 1.8 7.7 0.1 2.1 1 1 0 2 2 2 0 Tetratricopeptide repeat GAIN_A PF18619.1 EGG18798.1 - 0.096 12.9 1.9 11 6.3 0.0 3.0 3 0 0 3 3 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A STI1 PF17830.1 EGG18798.1 - 0.23 11.4 20.1 0.74 9.8 17.3 2.9 2 1 0 2 2 1 0 STI1 domain ComX PF05952.12 EGG18798.1 - 0.24 11.3 4.4 0.56 10.2 3.2 2.2 1 1 1 2 2 2 0 Bacillus competence pheromone ComX TBP PF00352.21 EGG18799.1 - 4.9e-65 215.5 1.4 6.7e-32 109.3 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EGG18799.1 - 3.6e-05 23.8 0.0 0.083 13.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EGG18799.1 - 0.023 14.5 0.1 0.096 12.5 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Ecl1 PF12855.7 EGG18799.1 - 0.66 11.1 5.7 0.87 10.7 5.7 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins AAA PF00004.29 EGG18800.1 - 5.9e-98 324.4 0.0 6.4e-49 165.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG18800.1 - 8.2e-27 92.7 7.2 4e-13 48.9 0.5 3.4 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EGG18800.1 - 5.5e-21 74.5 0.2 1.7e-20 73.0 0.2 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EGG18800.1 - 1.2e-14 54.4 0.0 2.6e-06 27.3 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGG18800.1 - 4.9e-13 49.6 0.0 8.5e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGG18800.1 - 5.6e-13 49.6 0.4 0.00015 22.2 0.0 3.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EGG18800.1 - 4.1e-12 46.3 0.0 1.5e-06 28.2 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 EGG18800.1 - 1.2e-11 44.2 0.0 2.7e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 EGG18800.1 - 3.5e-11 43.4 0.0 1.3e-05 25.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGG18800.1 - 4.4e-10 40.0 0.3 0.0036 17.6 0.1 3.8 2 2 1 3 3 2 2 AAA domain AAA_14 PF13173.6 EGG18800.1 - 6.2e-09 36.0 0.0 0.00041 20.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EGG18800.1 - 5.1e-08 32.5 0.0 0.0023 17.2 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 EGG18800.1 - 9.4e-08 31.7 0.6 0.0097 15.3 0.1 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGG18800.1 - 1.1e-07 32.5 0.0 0.016 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGG18800.1 - 1.2e-07 32.1 0.0 0.0076 16.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 EGG18800.1 - 6.3e-07 29.5 0.1 0.056 13.3 0.1 3.5 3 1 1 4 4 3 2 ATPase domain predominantly from Archaea Vps4_C PF09336.10 EGG18800.1 - 8.3e-07 28.9 0.3 2.8e-05 24.0 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 EGG18800.1 - 1e-06 29.3 0.2 0.015 15.8 0.0 3.4 3 1 0 3 3 2 2 ABC transporter IstB_IS21 PF01695.17 EGG18800.1 - 1.2e-06 28.4 0.1 0.059 13.1 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 EGG18800.1 - 1.3e-06 28.1 0.6 0.96 9.0 0.0 3.5 2 2 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EGG18800.1 - 2e-06 27.8 0.0 0.0034 17.2 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EGG18800.1 - 8e-06 25.9 0.2 0.15 12.0 0.0 3.2 3 1 0 3 3 3 2 NACHT domain AAA_28 PF13521.6 EGG18800.1 - 8.7e-06 26.1 0.0 0.2 11.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain Bac_DnaA PF00308.18 EGG18800.1 - 9.5e-06 25.6 0.0 0.02 14.7 0.0 2.8 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_7 PF12775.7 EGG18800.1 - 9.6e-06 25.2 0.1 0.16 11.5 0.0 3.2 3 1 0 3 3 3 2 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EGG18800.1 - 1e-05 24.8 0.1 0.06 12.4 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 EGG18800.1 - 2.4e-05 24.8 0.0 0.2 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EGG18800.1 - 2.5e-05 23.7 0.0 0.087 12.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TsaE PF02367.17 EGG18800.1 - 3.6e-05 23.7 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EGG18800.1 - 3.9e-05 23.5 0.1 0.074 12.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain Rad17 PF03215.15 EGG18800.1 - 4e-05 23.6 0.0 0.4 10.6 0.0 2.7 2 1 0 2 2 2 2 Rad17 P-loop domain ATPase PF06745.13 EGG18800.1 - 4.8e-05 22.8 0.2 2.9 7.2 0.0 3.3 3 0 0 3 3 3 1 KaiC Sigma54_activat PF00158.26 EGG18800.1 - 5.2e-05 23.0 0.0 0.31 10.7 0.0 3.1 3 1 0 3 3 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 EGG18800.1 - 0.00013 21.3 0.1 0.47 9.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.6 EGG18800.1 - 0.00016 21.8 0.0 0.29 11.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 EGG18800.1 - 0.00055 19.2 0.0 0.45 9.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.11 EGG18800.1 - 0.00063 19.6 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EGG18800.1 - 0.0015 18.6 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cytidylate_kin2 PF13189.6 EGG18800.1 - 0.0042 17.2 0.0 0.39 10.8 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family PhoH PF02562.16 EGG18800.1 - 0.0049 16.3 0.3 1.6 8.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.6 EGG18800.1 - 0.0077 16.6 0.5 9 6.6 0.1 3.3 3 1 0 4 4 2 0 AAA domain KAP_NTPase PF07693.14 EGG18800.1 - 0.009 15.3 0.1 0.66 9.2 0.0 3.1 2 2 1 3 3 3 1 KAP family P-loop domain NTPase_1 PF03266.15 EGG18800.1 - 0.01 15.8 0.2 8.8 6.2 0.0 3.5 3 0 0 3 3 3 0 NTPase TniB PF05621.11 EGG18800.1 - 0.012 15.0 0.0 1.7 8.0 0.0 3.3 4 0 0 4 4 3 0 Bacterial TniB protein AAA_11 PF13086.6 EGG18800.1 - 0.014 15.2 0.0 5.8 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGG18800.1 - 0.018 14.8 0.0 6.2 6.6 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation SKI PF01202.22 EGG18800.1 - 0.019 15.1 0.0 6.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_23 PF13476.6 EGG18800.1 - 0.019 15.5 0.0 11 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EGG18800.1 - 0.038 13.2 0.0 8 5.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Adeno_IVa2 PF02456.15 EGG18800.1 - 0.04 12.7 0.1 5.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AFG1_ATPase PF03969.16 EGG18800.1 - 0.046 12.6 0.0 4.8 6.0 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Cytidylate_kin PF02224.18 EGG18800.1 - 0.072 12.8 0.0 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_30 PF13604.6 EGG18800.1 - 0.16 11.7 0.1 23 4.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rhomboid PF01694.22 EGG18801.1 - 5.4e-15 55.7 18.1 8.5e-15 55.1 7.2 2.5 2 1 1 3 3 3 2 Rhomboid family DUF1751 PF08551.10 EGG18801.1 - 0.48 11.0 14.1 0.39 11.3 6.2 2.8 1 1 2 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) AAA PF00004.29 EGG18802.1 - 1.4e-56 190.5 1.3 9.5e-45 152.3 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG18802.1 - 9.7e-08 32.6 2.8 0.025 15.0 0.0 4.4 4 1 1 5 5 4 1 AAA ATPase domain AAA_14 PF13173.6 EGG18802.1 - 1.2e-06 28.6 0.2 0.21 11.6 0.8 3.8 3 1 0 3 3 3 2 AAA domain TsaE PF02367.17 EGG18802.1 - 6.1e-06 26.2 0.5 0.11 12.5 0.0 3.4 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EGG18802.1 - 7.8e-06 25.7 0.0 0.00019 21.2 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGG18802.1 - 1e-05 25.5 1.4 0.067 13.2 0.1 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGG18802.1 - 1.4e-05 25.5 0.1 0.0084 16.5 0.0 3.4 2 1 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 EGG18802.1 - 2.2e-05 24.7 0.5 0.044 14.0 0.0 3.5 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.6 EGG18802.1 - 2.8e-05 24.3 0.0 0.45 10.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.14 EGG18802.1 - 3e-05 24.2 0.3 0.1 12.7 0.0 3.5 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EGG18802.1 - 3.1e-05 23.8 0.1 0.21 11.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_lid_3 PF17862.1 EGG18802.1 - 3.9e-05 23.4 0.0 0.33 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_7 PF12775.7 EGG18802.1 - 0.00021 20.8 0.0 0.11 12.0 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 EGG18802.1 - 0.00022 21.2 0.1 1 9.3 0.0 3.4 3 0 0 3 3 3 2 NACHT domain Parvo_NS1 PF01057.17 EGG18802.1 - 0.0004 19.6 0.0 0.0011 18.1 0.0 1.7 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 EGG18802.1 - 0.00046 20.7 4.5 0.067 13.7 0.0 3.6 4 0 0 4 4 3 1 AAA domain TIP49 PF06068.13 EGG18802.1 - 0.0014 17.9 0.1 0.023 13.9 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EGG18802.1 - 0.0017 18.1 0.0 0.009 15.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_3 PF07726.11 EGG18802.1 - 0.003 17.4 0.0 0.93 9.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGG18802.1 - 0.0042 16.8 0.0 1.1 9.0 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EGG18802.1 - 0.005 16.2 0.0 0.035 13.5 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGG18802.1 - 0.0071 16.6 0.0 0.87 9.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain ATPase PF06745.13 EGG18802.1 - 0.0073 15.7 0.6 0.018 14.4 0.0 1.9 2 0 0 2 2 1 1 KaiC Vps4_C PF09336.10 EGG18802.1 - 0.0095 15.9 0.2 0.03 14.3 0.2 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 EGG18802.1 - 0.02 14.5 0.0 0.074 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGG18802.1 - 0.024 14.5 0.2 9.9 6.0 0.1 2.7 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 EGG18802.1 - 0.034 14.6 1.0 2.2 8.7 0.0 3.4 4 0 0 4 4 3 0 AAA domain Ribosomal_S17e PF00833.18 EGG18803.1 - 4.2e-58 194.6 0.5 5.1e-58 194.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal S17 EGF_2 PF07974.13 EGG18804.1 - 2.6 8.5 45.8 0.23 11.9 17.6 2.9 3 0 0 3 3 3 0 EGF-like domain DUF3844 PF12955.7 EGG18804.1 - 5.5 7.2 18.6 0.26 11.4 0.9 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3844) EB PF01683.18 EGG18805.1 - 0.0017 18.6 4.7 0.0047 17.2 4.7 1.7 1 0 0 1 1 1 1 EB module DUF4505 PF14956.6 EGG18805.1 - 0.023 14.4 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) LRR_8 PF13855.6 EGG18805.1 - 0.07 12.9 12.3 2.2 8.1 4.4 4.8 2 2 2 4 4 4 0 Leucine rich repeat EGF_2 PF07974.13 EGG18805.1 - 1.7 9.1 14.0 4.6 7.7 14.0 1.8 1 0 0 1 1 1 0 EGF-like domain zf-B_box PF00643.24 EGG18806.1 - 0.007 16.5 6.2 0.023 14.8 6.2 1.9 1 0 0 1 1 1 1 B-box zinc finger p450 PF00067.22 EGG18807.1 - 3.3e-200 665.7 4.8 2.9e-74 250.5 0.8 3.0 3 0 0 3 3 3 3 Cytochrome P450 DUF2362 PF10154.9 EGG18807.1 - 4.1e-05 22.7 2.9 0.24 10.3 0.0 3.1 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2362) WIYLD PF10440.9 EGG18807.1 - 0.0039 17.0 1.1 2.4 8.0 0.0 3.5 3 0 0 3 3 3 1 Ubiquitin-binding WIYLD domain DUF413 PF04219.12 EGG18807.1 - 0.031 14.3 4.3 0.63 10.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF DUF4248 PF14053.6 EGG18807.1 - 0.16 12.0 0.0 1e+02 3.0 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) Peripla_BP_5 PF13433.6 EGG18807.1 - 0.22 10.5 1.5 13 4.7 0.1 2.9 3 0 0 3 3 3 0 Periplasmic binding protein domain DUF1882 PF08966.11 EGG18807.1 - 3.1 8.1 6.7 6.2 7.2 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1882) DUF2393 PF09624.10 EGG18808.1 - 0.11 12.5 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) FAD_binding_3 PF01494.19 EGG18809.1 - 1.2e-21 77.3 0.0 2.4e-21 76.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGG18809.1 - 3.6e-08 33.4 0.0 0.0004 20.1 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGG18809.1 - 1.5e-06 28.4 0.1 4.4e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG18809.1 - 0.0002 20.7 1.0 0.0087 15.3 0.1 1.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG18809.1 - 0.0009 18.6 0.0 0.075 12.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EGG18809.1 - 0.0026 17.1 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family FAD_binding_2 PF00890.24 EGG18809.1 - 0.009 15.1 0.8 0.023 13.8 0.2 1.8 1 1 1 2 2 2 1 FAD binding domain SE PF08491.10 EGG18809.1 - 0.011 14.8 0.0 0.23 10.5 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.18 EGG18809.1 - 0.019 14.9 0.4 0.055 13.3 0.2 2.0 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGG18809.1 - 0.026 15.1 0.2 0.071 13.7 0.2 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.22 EGG18809.1 - 0.064 12.3 2.6 0.19 10.7 2.6 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EGG18809.1 - 0.07 13.7 0.0 0.28 11.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGG18809.1 - 0.1 11.6 0.1 0.25 10.3 0.1 1.7 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 EGG18809.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RRM_1 PF00076.22 EGG18810.1 - 0.00044 20.0 0.2 0.053 13.3 0.1 3.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PBP1_TM PF14812.6 EGG18810.1 - 4.2 7.8 7.7 0.97 9.8 3.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_19 PF14559.6 EGG18811.1 - 2.2e-09 37.7 1.8 0.22 12.1 0.0 6.4 5 3 2 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG18811.1 - 1.4e-07 31.8 13.8 0.15 12.9 0.1 7.6 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG18811.1 - 5.2e-05 23.1 7.3 18 5.8 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGG18811.1 - 0.00067 19.9 3.6 0.052 14.0 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG18811.1 - 0.0044 17.0 14.0 0.45 10.7 0.2 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG18811.1 - 0.01 16.5 7.3 0.18 12.5 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat MIP PF00230.20 EGG18813.1 - 4.1e-50 170.6 10.1 5.1e-50 170.3 10.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF4603 PF15376.6 EGG18813.1 - 0.027 11.9 0.0 0.035 11.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Peptidase_U4 PF03419.13 EGG18813.1 - 0.91 8.8 11.5 0.18 11.1 4.5 2.2 1 1 1 2 2 2 0 Sporulation factor SpoIIGA DUF3043 PF11241.8 EGG18814.1 - 0.086 12.9 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF5032 PF16435.5 EGG18815.1 - 0.0051 16.4 1.9 0.0095 15.4 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5032) Macoilin PF09726.9 EGG18816.1 - 0.073 11.6 2.6 0.065 11.8 2.6 1.2 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 EGG18816.1 - 0.081 11.7 0.5 0.075 11.8 0.5 1.1 1 0 0 1 1 1 0 Presenilin Squash PF00299.18 EGG18818.1 - 0.16 12.0 0.7 0.47 10.5 0.2 1.9 2 0 0 2 2 2 0 Squash family serine protease inhibitor SCAMP PF04144.13 EGG18819.1 - 7.5e-29 101.2 12.7 1.1e-28 100.7 12.7 1.2 1 0 0 1 1 1 1 SCAMP family FNIP PF05725.12 EGG18819.1 - 6.6e-13 48.6 9.6 5.9e-07 29.5 0.4 5.7 3 2 3 6 6 6 5 FNIP Repeat ESSS PF10183.9 EGG18819.1 - 5.4 7.3 4.9 0.92 9.7 0.3 2.2 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Ank_2 PF12796.7 EGG18820.1 - 2.4e-10 40.8 1.2 1.4e-05 25.6 0.1 2.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG18820.1 - 5e-06 26.5 0.6 2.4 9.0 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EGG18820.1 - 0.00044 20.8 0.4 0.0037 17.8 0.1 2.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18820.1 - 0.0034 17.6 0.5 0.36 11.2 0.1 2.9 1 1 2 3 3 3 1 Ankyrin repeats (many copies) NARP1 PF12569.8 EGG18821.1 - 3.2e-135 452.0 9.6 3.2e-135 452.0 9.6 2.3 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EGG18821.1 - 3.7e-18 64.1 9.0 0.00043 20.2 0.0 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGG18821.1 - 9.3e-13 47.8 0.0 2.2 9.3 0.0 8.1 7 1 2 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG18821.1 - 2.2e-10 40.9 6.1 0.012 16.1 0.1 6.2 4 3 4 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGG18821.1 - 2.7e-09 36.7 5.2 7.9e-05 22.8 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG18821.1 - 4.1e-09 35.9 5.8 0.017 14.9 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG18821.1 - 1.3e-07 32.2 0.0 8.5 7.1 0.0 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG18821.1 - 6.4e-06 26.4 1.3 0.59 10.5 0.0 6.1 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG18821.1 - 6.9e-06 25.9 5.8 0.029 14.6 0.1 6.3 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGG18821.1 - 0.0001 21.9 2.7 3.4 7.4 0.0 6.6 6 1 1 7 7 7 1 TPR repeat Fis1_TPR_C PF14853.6 EGG18821.1 - 0.0018 18.3 0.3 0.56 10.3 0.0 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EGG18821.1 - 0.0069 17.0 3.3 18 6.2 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat DNA_photolyase PF00875.18 EGG18821.1 - 0.0078 16.2 0.2 0.28 11.2 0.0 2.8 2 0 0 2 2 2 1 DNA photolyase TPR_20 PF14561.6 EGG18821.1 - 0.012 15.9 1.3 3.2 8.1 0.0 3.9 4 1 0 4 4 3 0 Tetratricopeptide repeat PRCC PF10253.9 EGG18821.1 - 0.054 14.3 3.8 0.13 13.0 3.8 1.6 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting ANAPC3 PF12895.7 EGG18821.1 - 0.17 12.1 13.1 21 5.4 0.0 6.3 5 3 0 7 7 6 0 Anaphase-promoting complex, cyclosome, subunit 3 HNF-1_N PF04814.13 EGG18821.1 - 0.32 11.6 4.0 0.17 12.5 0.3 2.2 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus FAM150 PF15129.6 EGG18821.1 - 4.4 7.5 6.5 0.84 9.8 1.0 2.6 3 1 0 3 3 3 0 FAM150 family Sigma70_ner PF04546.13 EGG18822.1 - 3.2e-05 23.9 7.2 6.9e-05 22.8 7.2 1.6 1 0 0 1 1 1 1 Sigma-70, non-essential region BSP_II PF05432.11 EGG18822.1 - 0.00014 21.7 8.1 0.0019 18.0 8.3 2.1 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Mpp10 PF04006.12 EGG18822.1 - 0.00019 20.0 5.7 0.0003 19.4 5.7 1.3 1 0 0 1 1 1 1 Mpp10 protein SDA1 PF05285.12 EGG18822.1 - 0.0027 17.2 8.7 0.0027 17.2 8.7 1.4 2 0 0 2 2 1 1 SDA1 CobT PF06213.12 EGG18822.1 - 0.0081 15.6 9.5 0.014 14.8 9.5 1.4 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 EGG18822.1 - 0.0099 15.3 6.3 0.015 14.7 6.3 1.2 1 0 0 1 1 1 1 BUD22 RNA_pol_3_Rpc31 PF11705.8 EGG18822.1 - 0.012 15.9 14.6 0.024 14.9 14.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.18 EGG18822.1 - 0.022 14.7 3.9 0.046 13.6 3.9 1.5 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.14 EGG18822.1 - 0.068 11.5 8.3 0.12 10.6 8.3 1.4 1 0 0 1 1 1 0 CDC45-like protein DARPP-32 PF05395.12 EGG18822.1 - 0.076 13.2 8.0 0.43 10.8 6.2 2.2 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 TFIIA PF03153.13 EGG18822.1 - 0.094 12.7 6.6 0.15 12.0 6.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 EGG18822.1 - 0.096 10.9 15.1 0.14 10.3 15.1 1.2 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 EGG18822.1 - 0.097 12.7 9.1 0.026 14.6 5.3 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal PPP4R2 PF09184.11 EGG18822.1 - 0.14 11.7 15.9 0.28 10.7 15.9 1.5 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 EGG18822.1 - 0.18 9.8 26.7 0.085 11.0 23.3 1.9 2 0 0 2 2 2 0 DNA polymerase phi PTPRCAP PF15713.5 EGG18822.1 - 0.32 11.3 12.4 0.68 10.2 12.4 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated TRAP_alpha PF03896.16 EGG18822.1 - 0.6 9.3 9.1 0.22 10.7 6.4 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.14 EGG18822.1 - 0.64 9.8 9.9 2 8.2 9.9 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFB6 PF17110.5 EGG18822.1 - 0.94 9.2 6.9 0.44 10.3 3.7 2.0 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Spb1_C PF07780.12 EGG18822.1 - 1.4 8.5 8.1 3.2 7.4 8.1 1.5 1 0 0 1 1 1 0 Spb1 C-terminal domain DUF4746 PF15928.5 EGG18822.1 - 5.6 6.3 14.3 0.58 9.5 9.9 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4746) Paf1 PF03985.13 EGG18822.1 - 6.8 5.6 17.2 13 4.7 17.2 1.3 1 0 0 1 1 1 0 Paf1 PIGA PF08288.12 EGG18823.1 - 1.4e-43 147.4 1.9 2.2e-43 146.7 0.7 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 EGG18823.1 - 1.7e-27 96.1 0.0 2.7e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGG18823.1 - 1.7e-26 93.2 0.1 5e-26 91.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EGG18823.1 - 3.8e-22 79.2 0.1 6.3e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGG18823.1 - 9.6e-08 32.6 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EGG18823.1 - 1.9e-05 24.7 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 EGG18823.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.7 1 1 0 1 1 1 0 Starch synthase catalytic domain DEAD PF00270.29 EGG18826.1 - 1.5e-48 164.8 0.1 3e-48 163.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG18826.1 - 8.2e-28 97.0 0.3 1.1e-26 93.3 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG18826.1 - 0.00012 22.1 0.2 0.00041 20.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Nitroreductase PF00881.24 EGG18826.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.6 1 1 0 1 1 1 0 Nitroreductase family USP19_linker PF16602.5 EGG18826.1 - 0.57 10.7 4.7 0.24 12.0 1.2 2.1 2 0 0 2 2 2 0 Linker region of USP19 deubiquitinase DEAD PF00270.29 EGG18827.1 - 2.3e-45 154.5 2.8 3.2e-45 154.0 0.0 2.4 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG18827.1 - 5e-27 94.4 0.1 3.2e-26 91.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGG18827.1 - 1.4e-15 57.3 0.0 2.7e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGG18827.1 - 6.5e-07 29.5 0.0 6.5e-07 29.5 0.0 3.9 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit KaiA PF07688.12 EGG18828.1 - 0.011 15.8 0.1 0.054 13.6 0.1 2.1 2 0 0 2 2 2 0 KaiA C-terminal domain Viral_NABP PF05515.11 EGG18828.1 - 0.096 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral nucleic acid binding LRR_8 PF13855.6 EGG18829.1 - 1.4e-08 34.3 18.4 0.00056 19.6 4.0 4.3 4 0 0 4 4 4 3 Leucine rich repeat zf-CHC2 PF01807.20 EGG18829.1 - 0.0005 19.8 0.2 1.6 8.6 0.0 2.6 2 0 0 2 2 2 2 CHC2 zinc finger CorC_HlyC PF03471.17 EGG18829.1 - 0.0071 16.3 0.0 2.9 7.9 0.0 2.6 2 0 0 2 2 2 2 Transporter associated domain MRP-S25 PF13741.6 EGG18830.1 - 0.039 13.5 7.2 0.049 13.2 7.2 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 DUF4175 PF13779.6 EGG18830.1 - 0.23 9.3 2.0 0.26 9.1 2.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spt5_N PF11942.8 EGG18830.1 - 1.9 9.5 7.8 2.8 9.0 7.8 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal LRR_8 PF13855.6 EGG18831.1 - 0.0015 18.3 3.2 0.37 10.6 0.3 4.6 3 1 1 4 4 4 3 Leucine rich repeat FNIP PF05725.12 EGG18831.1 - 1 9.6 23.5 3.9 7.7 0.2 6.4 6 1 1 7 7 7 0 FNIP Repeat Sua5_yciO_yrdC PF01300.18 EGG18832.1 - 1.4e-45 155.0 0.0 3.1e-45 153.9 0.0 1.6 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EGG18832.1 - 1.7e-13 51.3 0.1 5.2e-12 46.5 0.0 2.7 2 1 0 2 2 2 1 Putative GTP-binding controlling metal-binding SSTK-IP PF15836.5 EGG18833.1 - 0.0006 19.9 2.4 0.00075 19.6 2.4 1.2 1 0 0 1 1 1 1 SSTK-interacting protein, TSSK6-activating co-chaperone protein RhoGAP PF00620.27 EGG18833.1 - 0.044 13.6 0.3 0.06 13.2 0.3 1.2 1 0 0 1 1 1 0 RhoGAP domain LIDHydrolase PF10230.9 EGG18834.1 - 3.4e-57 194.0 0.5 4.2e-57 193.7 0.5 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 EGG18834.1 - 7.6e-05 22.1 0.0 0.0001 21.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG18834.1 - 0.00023 20.9 0.1 0.0075 15.9 0.1 2.6 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EGG18834.1 - 0.0023 18.0 0.0 0.0052 16.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DUF1749 PF08538.10 EGG18834.1 - 0.031 13.4 0.0 0.078 12.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 EGG18834.1 - 0.098 12.1 0.0 0.29 10.6 0.0 1.8 2 1 1 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGG18834.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold ALG11_N PF15924.5 EGG18834.1 - 0.66 10.0 4.7 1.7 8.7 2.3 2.6 1 1 0 1 1 1 0 ALG11 mannosyltransferase N-terminus GRP PF07172.11 EGG18835.1 - 1.5 9.6 19.2 1.2 9.9 14.0 2.7 2 0 0 2 2 2 0 Glycine rich protein family Clathrin PF00637.20 EGG18836.1 - 2.4e-19 69.6 2.0 2.4e-19 69.6 2.0 2.2 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_2 PF10367.9 EGG18836.1 - 2.5e-07 31.1 1.1 5.6e-07 30.0 0.3 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 EGG18836.1 - 0.001 19.0 0.2 0.0032 17.5 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger Vps39_1 PF10366.9 EGG18836.1 - 0.0025 18.1 1.7 0.01 16.1 0.8 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 WD40 PF00400.32 EGG18836.1 - 0.0058 17.5 0.0 0.026 15.4 0.0 2.3 1 0 0 1 1 1 1 WD domain, G-beta repeat zf-rbx1 PF12678.7 EGG18836.1 - 0.33 11.3 4.2 0.11 12.7 0.6 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGG18836.1 - 0.73 9.8 6.2 0.08 12.9 0.9 2.2 2 0 0 2 2 2 0 zinc-RING finger domain UBX PF00789.20 EGG18837.1 - 1.3e-11 44.5 0.2 9.2e-11 41.8 0.2 2.4 1 1 0 1 1 1 1 UBX domain UPF0697 PF15117.6 EGG18837.1 - 2 8.5 7.0 0.8 9.8 1.9 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 Actin PF00022.19 EGG18838.1 - 1.1e-12 47.2 0.1 1.1e-12 47.2 0.1 1.0 1 0 0 1 1 1 1 Actin ALP_N PF17989.1 EGG18838.1 - 0.11 12.7 0.0 0.11 12.7 0.0 1.0 1 0 0 1 1 1 0 Actin like proteins N terminal domain Actin PF00022.19 EGG18839.1 - 3.4e-125 417.8 0.0 1.3e-124 415.9 0.0 1.7 1 1 0 1 1 1 1 Actin TRP PF06011.12 EGG18841.1 - 9.5e-05 21.3 30.7 0.0012 17.7 26.2 3.3 1 1 1 2 2 2 1 Transient receptor potential (TRP) ion channel EGF_2 PF07974.13 EGG18841.1 - 0.00041 20.7 64.5 0.0015 18.9 7.3 4.5 4 0 0 4 4 4 3 EGF-like domain PQQ_3 PF13570.6 EGG18841.1 - 0.6 10.7 3.9 12 6.5 0.1 3.0 2 0 0 2 2 2 0 PQQ-like domain Acyltransf_C PF16076.5 EGG18843.1 - 2.5e-18 66.0 0.0 4.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 EGG18843.1 - 1.6e-16 60.2 0.0 3.2e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Ank_2 PF12796.7 EGG18844.1 - 1.3e-21 76.9 0.2 2.3e-09 37.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18844.1 - 3.2e-17 62.6 0.1 1.5e-09 38.2 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG18844.1 - 7.8e-17 61.1 1.5 1.7e-12 47.3 0.1 4.7 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EGG18844.1 - 9.3e-17 60.7 0.8 1.1e-05 25.7 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EGG18844.1 - 2.7e-14 51.8 0.1 1.6e-05 24.9 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 EGG18844.1 - 5.1e-12 45.5 6.5 9.1e-12 44.7 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG18844.1 - 5.5e-05 22.9 7.3 0.00012 21.9 7.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGG18844.1 - 0.0039 17.1 7.6 0.0072 16.3 7.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGG18844.1 - 0.042 14.2 8.8 0.086 13.2 8.8 1.6 1 0 0 1 1 1 0 Ring finger domain Abhydrolase_1 PF00561.20 EGG18845.1 - 3.4e-09 36.7 0.1 5.9e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG18845.1 - 6.8e-08 33.4 0.0 7.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG18845.1 - 0.00011 21.6 0.1 0.00016 21.1 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 EGG18845.1 - 0.0035 16.6 0.1 0.0056 15.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) V-SNARE_C PF12352.8 EGG18846.1 - 2.4e-08 34.1 1.9 5e-08 33.1 1.9 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 EGG18846.1 - 0.00041 20.3 1.6 0.00059 19.8 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) PspA_IM30 PF04012.12 EGG18846.1 - 0.0048 16.5 1.0 0.0056 16.3 1.0 1.2 1 0 0 1 1 1 1 PspA/IM30 family RmuC PF02646.16 EGG18846.1 - 0.0059 15.8 0.6 0.0059 15.8 0.6 1.5 2 0 0 2 2 2 1 RmuC family Peptidase_C98 PF15499.6 EGG18846.1 - 0.021 14.3 0.3 0.023 14.2 0.3 1.2 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Sec20 PF03908.13 EGG18846.1 - 0.032 14.1 1.1 0.049 13.5 0.6 1.5 1 1 1 2 2 2 0 Sec20 SNARE PF05739.19 EGG18846.1 - 0.036 14.1 0.4 0.064 13.3 0.4 1.4 1 0 0 1 1 1 0 SNARE domain VGPC1_C PF16799.5 EGG18846.1 - 0.05 13.6 1.6 0.095 12.7 1.6 1.5 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF3772 PF12607.8 EGG18846.1 - 0.056 13.2 0.6 0.13 12.0 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) DUF1664 PF07889.12 EGG18846.1 - 0.53 10.3 3.7 1.2 9.2 3.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 EGG18846.1 - 0.91 8.8 6.7 2.5 7.3 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) XhlA PF10779.9 EGG18846.1 - 4.3 7.6 7.3 1.4 9.2 2.5 2.1 1 1 0 2 2 2 0 Haemolysin XhlA VIT1 PF01988.19 EGG18847.1 - 2.4e-42 145.2 4.5 4.3e-40 137.9 0.4 2.1 2 0 0 2 2 2 2 VIT family DUF2244 PF10003.9 EGG18847.1 - 0.7 9.6 0.0 0.7 9.6 0.0 2.5 2 1 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4064 PF13273.6 EGG18847.1 - 0.87 9.9 16.2 1.2 9.5 13.0 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Peptidase_C50 PF03568.17 EGG18848.1 - 9.5e-72 242.3 0.7 9.5e-72 242.3 0.7 4.9 4 2 0 5 5 5 1 Peptidase family C50 CHAT PF12770.7 EGG18848.1 - 0.00018 21.0 0.0 0.0009 18.7 0.0 2.1 1 1 0 1 1 1 1 CHAT domain TPR_2 PF07719.17 EGG18848.1 - 0.00035 20.5 3.4 11 6.4 0.1 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG18848.1 - 0.0022 18.2 3.1 6.2 7.2 0.1 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat Sigma70_ner PF04546.13 EGG18848.1 - 0.004 17.1 2.3 0.004 17.1 2.3 4.5 4 0 0 4 4 4 1 Sigma-70, non-essential region TPR_8 PF13181.6 EGG18848.1 - 0.11 12.8 6.3 15 6.1 0.3 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 EGG18849.1 - 3e-17 62.2 0.1 5.4e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hamartin PF04388.12 EGG18849.1 - 0.71 8.5 18.4 0.81 8.3 18.4 1.2 1 0 0 1 1 1 0 Hamartin protein GPHR_N PF12537.8 EGG18850.1 - 1.6e-10 40.9 0.8 4.9e-10 39.4 0.1 2.2 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal RICTOR_V PF14668.6 EGG18850.1 - 0.041 14.1 1.0 0.66 10.2 0.1 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Yip1 PF04893.17 EGG18851.1 - 2.3e-11 43.7 15.3 6.3e-11 42.3 15.3 1.7 1 1 0 1 1 1 1 Yip1 domain TMEM252 PF15664.5 EGG18851.1 - 0.4 10.4 3.6 1.1 9.0 3.6 1.8 1 0 0 1 1 1 0 Transmembrane protein 252 family Glyco_hydro_25 PF01183.20 EGG18852.1 - 3.3e-14 53.5 0.0 3.8e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 DUF1906 PF08924.11 EGG18852.1 - 1.9e-05 24.9 0.8 0.00013 22.1 0.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1906) DUF1610 PF07754.11 EGG18852.1 - 0.17 11.9 0.4 0.17 11.9 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) CHCH PF06747.13 EGG18852.1 - 0.21 11.8 1.0 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 CHCH domain zf-MYND PF01753.18 EGG18853.1 - 0.071 13.2 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 MYND finger Trypsin_2 PF13365.6 EGG18854.1 - 1.3e-05 26.1 0.0 2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGG18854.1 - 0.018 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Trypsin Trypsin_2 PF13365.6 EGG18855.1 - 9.5e-08 33.1 0.0 1.3e-07 32.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGG18855.1 - 0.046 13.5 0.1 0.088 12.6 0.1 1.6 1 1 0 1 1 1 0 Trypsin cobW PF02492.19 EGG18856.1 - 2e-49 167.6 0.1 1.7e-48 164.6 0.1 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGG18856.1 - 3.8e-11 42.8 0.0 6.1e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EGG18856.1 - 0.00013 21.9 1.8 0.085 12.8 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGG18856.1 - 0.027 14.7 0.0 0.91 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EGG18856.1 - 0.029 13.4 0.1 0.057 12.5 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PND PF17949.1 EGG18856.1 - 0.043 14.1 0.9 0.1 12.9 0.9 1.6 1 0 0 1 1 1 0 FANCM pseudonuclease domain AAA_29 PF13555.6 EGG18856.1 - 0.068 12.9 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG18856.1 - 0.08 13.3 0.2 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 EGG18856.1 - 0.092 12.8 0.0 0.38 10.9 0.0 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EGG18856.1 - 0.62 10.6 2.6 7.6 7.1 1.8 2.9 2 1 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 EGG18856.1 - 0.79 9.5 4.8 7.1 6.3 0.4 3.5 2 2 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 EGG18856.1 - 4 7.9 5.8 9.4 6.7 5.8 1.8 1 1 0 1 1 1 0 AAA domain NAC PF01849.18 EGG18857.1 - 6.8e-21 74.0 0.1 1.1e-20 73.3 0.1 1.3 1 0 0 1 1 1 1 NAC domain 2-oxoacid_dh PF00198.23 EGG18858.1 - 1.2e-82 276.9 0.2 4.8e-82 274.9 0.0 1.9 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGG18858.1 - 3.5e-20 71.6 0.1 7e-20 70.6 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EGG18858.1 - 1.3e-13 51.0 0.1 5.4e-13 49.0 0.1 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EGG18858.1 - 0.035 13.9 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like HlyD_D23 PF16576.5 EGG18858.1 - 0.046 12.9 0.2 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Ribosomal_60s PF00428.19 EGG18858.1 - 0.91 10.2 7.4 7.2 7.3 2.3 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_L9_N PF01281.19 EGG18859.1 - 1.2e-16 59.9 0.0 1.3e-15 56.6 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 EGG18859.1 - 2.4e-06 27.9 0.1 4.1e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Acetyltransf_1 PF00583.25 EGG18861.1 - 9.2e-05 22.7 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG18861.1 - 0.0012 19.2 0.0 0.0046 17.4 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGG18861.1 - 0.0034 17.4 0.0 0.0063 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG18861.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EGG18861.1 - 0.022 14.7 0.1 0.047 13.7 0.1 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Pkinase PF00069.25 EGG18861.1 - 0.047 13.0 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain TylF PF05711.11 EGG18861.1 - 0.16 11.2 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Proteasom_PSMB PF10508.9 EGG18862.1 - 1.6e-28 99.5 2.7 3.3e-15 55.6 0.0 3.1 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit KdgT PF03812.13 EGG18862.1 - 0.025 13.9 0.3 0.038 13.3 0.3 1.2 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease C4bp_oligo PF18453.1 EGG18862.1 - 0.03 14.5 0.5 0.48 10.7 0.0 2.8 3 0 0 3 3 3 0 Oligomerization domain of C4b-binding protein alpha PH PF00169.29 EGG18864.1 - 8.3e-21 74.5 3.1 1.7e-20 73.4 3.1 1.6 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 EGG18864.1 - 1.4e-07 31.6 0.7 2.9e-07 30.5 0.7 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGG18864.1 - 4.2e-05 23.9 4.3 4.2e-05 23.9 4.3 3.0 3 1 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.6 EGG18864.1 - 0.0011 19.3 0.2 0.0028 18.0 0.1 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 EGG18864.1 - 0.005 17.1 0.6 0.0095 16.2 0.6 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 EGG18864.1 - 0.0073 16.6 0.3 0.02 15.2 0.1 1.9 2 0 0 2 2 2 1 Plant pleckstrin homology-like region BCL_N PF04714.13 EGG18864.1 - 0.034 14.2 0.3 0.14 12.2 0.3 2.0 1 0 0 1 1 1 0 BCL7, N-terminal conserver region DUF4162 PF13732.6 EGG18864.1 - 0.096 13.4 0.9 32 5.3 0.3 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4162) Mcp5_PH PF12814.7 EGG18864.1 - 0.12 12.5 1.6 0.55 10.4 0.3 2.2 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology PAPS_reduct PF01507.19 EGG18865.1 - 4.2e-27 95.3 0.0 1.4e-21 77.3 0.0 2.7 2 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DUF2572 PF10833.8 EGG18865.1 - 0.45 10.3 1.9 0.69 9.6 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) PBP PF01161.20 EGG18866.1 - 1.4e-22 80.4 0.0 1.7e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein AAA PF00004.29 EGG18867.1 - 2.1e-14 54.1 0.0 4.3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG18867.1 - 1.6e-11 44.9 0.1 3e-10 40.8 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG18867.1 - 1.7e-10 41.3 0.0 3.1e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 EGG18867.1 - 6.4e-09 35.8 0.6 2.4e-08 34.0 0.6 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 EGG18867.1 - 3.2e-06 27.5 0.0 1.5e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EGG18867.1 - 0.00051 19.5 0.2 0.00089 18.7 0.2 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_18 PF13238.6 EGG18867.1 - 0.00081 19.9 0.4 0.0071 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EGG18867.1 - 0.0011 18.3 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 EGG18867.1 - 0.0025 17.8 1.9 0.0025 17.8 1.9 2.1 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EGG18867.1 - 0.0046 16.7 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EGG18867.1 - 0.0066 15.5 0.1 0.014 14.4 0.1 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EGG18867.1 - 0.01 15.8 0.1 0.027 14.4 0.1 1.7 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.6 EGG18867.1 - 0.018 14.8 0.5 0.018 14.8 0.5 2.8 2 2 0 2 2 1 0 AAA domain NB-ARC PF00931.22 EGG18867.1 - 0.021 14.0 0.1 0.041 13.1 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 EGG18867.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 EGG18867.1 - 0.026 13.8 0.0 0.026 13.8 0.0 1.9 2 0 0 2 2 1 0 KAP family P-loop domain Viral_helicase1 PF01443.18 EGG18867.1 - 0.027 14.2 3.7 1 9.1 0.1 2.8 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_32 PF13654.6 EGG18867.1 - 0.034 12.9 0.1 0.062 12.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGG18867.1 - 0.053 13.0 0.2 0.14 11.6 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_35 PF14516.6 EGG18867.1 - 0.053 12.3 0.7 0.1 11.4 0.1 1.6 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.17 EGG18867.1 - 0.091 12.5 0.0 0.36 10.6 0.0 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 EGG18867.1 - 0.22 11.5 1.1 0.66 10.0 0.1 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF773 PF05600.12 EGG18868.1 - 1.3e-125 420.1 20.9 2e-125 419.4 20.9 1.3 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 DUF4535 PF15054.6 EGG18868.1 - 0.0051 16.5 0.4 0.015 15.0 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4535) NTP_transf_6 PF06042.11 EGG18868.1 - 0.015 15.2 1.0 0.03 14.2 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyltransferase Sec8_exocyst PF04048.14 EGG18868.1 - 0.023 14.6 10.3 0.31 10.9 1.7 3.4 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain PspA_IM30 PF04012.12 EGG18868.1 - 0.035 13.7 6.0 0.021 14.4 2.1 2.0 2 0 0 2 2 2 0 PspA/IM30 family THOC7 PF05615.13 EGG18868.1 - 0.051 13.9 12.4 3.5 7.9 0.1 2.8 2 1 0 2 2 2 0 Tho complex subunit 7 TMF_TATA_bd PF12325.8 EGG18868.1 - 0.6 10.4 9.9 1.4 9.2 4.1 3.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding COMP PF11598.8 EGG18868.1 - 3.7 8.1 6.3 13 6.4 6.3 2.0 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein APG6_N PF17675.1 EGG18868.1 - 5.3 7.6 12.5 6.4 7.3 5.4 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF5339 PF17274.2 EGG18868.1 - 9.9 7.1 10.7 72 4.3 4.0 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5339) Ank_2 PF12796.7 EGG18869.1 - 2.7e-06 27.9 0.1 0.044 14.4 0.0 4.7 2 1 4 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG18869.1 - 0.00042 20.8 0.9 26 5.5 0.0 6.0 6 1 0 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18869.1 - 0.0036 17.7 1.4 28 5.7 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat DUF1084 PF06454.11 EGG18871.1 - 2.6e-12 46.7 11.5 3.8e-12 46.2 11.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) NPP PF08384.10 EGG18876.1 - 0.89 9.7 3.4 2.2 8.4 3.4 1.6 1 0 0 1 1 1 0 Pro-opiomelanocortin, N-terminal region VASt PF16016.5 EGG18877.1 - 8.9e-27 94.4 0.1 8.9e-27 94.4 0.1 2.4 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain TFIIA PF03153.13 EGG18877.1 - 2.8e-05 24.3 26.3 2.8e-05 24.3 26.3 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Coilin_N PF15862.5 EGG18877.1 - 0.0024 17.7 9.7 3.2 7.5 12.2 2.5 2 0 0 2 2 2 1 Coilin N-terminus Spt20 PF12090.8 EGG18877.1 - 0.0027 17.4 34.9 0.0027 17.4 34.9 2.4 2 0 0 2 2 2 1 Spt20 family Neur_chan_memb PF02932.16 EGG18877.1 - 0.017 15.2 2.7 0.031 14.3 2.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4643 PF15485.6 EGG18877.1 - 0.018 14.9 11.0 0.018 14.9 11.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4643) RR_TM4-6 PF06459.12 EGG18877.1 - 0.021 14.7 9.3 0.037 13.8 9.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1980 PF09323.10 EGG18877.1 - 0.047 13.6 4.4 0.084 12.8 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF913 PF06025.12 EGG18877.1 - 0.05 12.6 6.8 0.082 11.9 6.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) eIF-3_zeta PF05091.12 EGG18877.1 - 0.067 12.2 13.7 0.11 11.4 13.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 EGG18877.1 - 0.22 11.7 9.4 0.46 10.6 9.4 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CobT PF06213.12 EGG18877.1 - 0.27 10.6 15.8 0.41 10.0 15.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Rpp20 PF12328.8 EGG18877.1 - 0.31 11.0 15.8 1.5 8.8 15.8 2.1 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P SpoIIP PF07454.11 EGG18877.1 - 0.31 10.5 12.8 0.53 9.7 12.8 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4834 PF16118.5 EGG18877.1 - 0.32 12.0 12.9 0.87 10.6 12.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PTPRCAP PF15713.5 EGG18877.1 - 0.34 11.2 11.4 0.73 10.1 11.4 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF3408 PF11888.8 EGG18877.1 - 0.37 10.9 13.1 0.77 9.9 13.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Connexin PF00029.19 EGG18877.1 - 0.46 10.2 6.0 0.73 9.6 6.0 1.2 1 0 0 1 1 1 0 Connexin Pex14_N PF04695.13 EGG18877.1 - 0.72 10.5 36.1 0.12 13.0 20.8 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EIIBC-GUT_N PF03612.14 EGG18877.1 - 0.96 9.2 11.1 1.9 8.2 11.1 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CSG2 PF16965.5 EGG18877.1 - 1.4 7.8 6.8 2.6 6.9 6.8 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator DDHD PF02862.17 EGG18877.1 - 1.9 8.6 15.8 0.11 12.7 10.2 1.7 2 1 0 2 2 2 0 DDHD domain DUF4770 PF15994.5 EGG18877.1 - 2.1 8.6 16.5 5.1 7.3 16.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FAM176 PF14851.6 EGG18877.1 - 2.2 7.9 6.7 4.5 6.9 6.7 1.4 1 0 0 1 1 1 0 FAM176 family CLN3 PF02487.17 EGG18877.1 - 2.4 7.1 9.6 3.5 6.6 9.6 1.2 1 0 0 1 1 1 0 CLN3 protein OATP PF03137.20 EGG18877.1 - 2.5 6.3 8.7 3.6 5.8 8.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AIF_C PF14721.6 EGG18877.1 - 2.6 8.4 11.1 3.6 8.0 8.0 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF702 PF05142.12 EGG18877.1 - 2.9 8.4 14.0 7.7 7.0 14.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF702) ALMT PF11744.8 EGG18877.1 - 2.9 6.6 9.5 4.5 6.0 9.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM60A PF15396.6 EGG18877.1 - 3.1 7.7 10.9 6.5 6.7 10.9 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 EGG18877.1 - 3.3 6.4 15.8 5 5.8 15.8 1.2 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 EGG18877.1 - 3.7 7.3 12.6 6.6 6.5 12.6 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain BORG_CEP PF14957.6 EGG18877.1 - 4.1 8.6 13.5 0.11 13.7 6.1 2.1 2 1 0 2 2 2 0 Cdc42 effector CCDC53 PF10152.9 EGG18877.1 - 6.1 7.3 20.0 0.029 14.8 8.4 2.3 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex EOS1 PF12326.8 EGG18877.1 - 6.5 6.6 9.7 14 5.5 9.7 1.5 1 0 0 1 1 1 0 N-glycosylation protein DUF4175 PF13779.6 EGG18877.1 - 8.4 4.2 32.2 14 3.4 32.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Brix PF04427.18 EGG18879.1 - 2.9e-33 115.6 0.0 4e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF4128 PF13554.6 EGG18879.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function Rap_GAP PF02145.15 EGG18880.1 - 1.3e-28 99.8 0.0 2.5e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP RPN2_C PF18004.1 EGG18880.1 - 0.03 14.3 1.6 0.056 13.4 1.6 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SR-25 PF10500.9 EGG18880.1 - 0.31 10.6 5.3 0.56 9.8 5.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Auts2 PF15336.6 EGG18880.1 - 2.1 8.4 8.0 1.7 8.7 1.5 2.3 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein RhoGAP PF00620.27 EGG18881.1 - 2.8e-05 24.0 0.1 8.2e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain DENN PF02141.21 EGG18883.1 - 1.3e-33 116.5 3.0 2.9e-29 102.3 1.7 2.8 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 EGG18883.1 - 5.9e-06 26.9 1.9 2.7e-05 24.8 0.6 2.9 2 1 0 2 2 2 1 uDENN domain Avl9 PF09794.9 EGG18883.1 - 8.6e-05 21.4 4.9 0.00014 20.7 3.0 2.2 2 1 0 2 2 2 1 Transport protein Avl9 SPA PF08616.10 EGG18883.1 - 0.00013 21.9 0.7 0.00036 20.5 0.7 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis Abhydrolase_2 PF02230.16 EGG18884.1 - 8.5e-56 189.2 0.0 1e-55 188.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGG18884.1 - 1.5e-10 41.1 0.0 4.7e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EGG18884.1 - 2.8e-06 27.0 0.0 3.5e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EGG18884.1 - 1.8e-05 24.4 0.0 0.00098 18.6 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGG18884.1 - 3.9e-05 23.0 0.0 0.062 12.6 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Esterase PF00756.20 EGG18884.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.4 1 1 0 1 1 1 0 Putative esterase PAF-AH_p_II PF03403.13 EGG18884.1 - 0.023 13.2 0.0 0.78 8.2 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II ERAP1_C PF11838.8 EGG18884.1 - 0.062 12.8 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Abhydrolase_3 PF07859.13 EGG18884.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DIRP PF06584.13 EGG18885.1 - 1.3e-19 70.3 2.8 4e-19 68.8 2.8 1.9 1 0 0 1 1 1 1 DIRP Myb_DNA-binding PF00249.31 EGG18885.1 - 0.018 15.2 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain ABC_tran PF00005.27 EGG18886.1 - 1.1e-22 81.0 0.0 1.7e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EGG18886.1 - 9.5e-09 35.0 2.5 1.5e-08 34.3 2.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter SMC_N PF02463.19 EGG18886.1 - 0.00043 19.8 0.2 0.0011 18.5 0.2 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGG18886.1 - 0.00098 19.5 0.0 0.015 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EGG18886.1 - 0.0012 19.2 0.0 0.0032 17.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGG18886.1 - 0.0048 17.2 0.1 0.036 14.3 0.1 2.4 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGG18886.1 - 0.0082 16.5 0.1 0.13 12.7 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 EGG18886.1 - 0.01 15.8 0.2 0.029 14.3 0.1 1.9 1 1 1 2 2 2 0 Rad17 P-loop domain DUF815 PF05673.13 EGG18886.1 - 0.012 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EGG18886.1 - 0.024 14.1 0.0 0.049 13.2 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EGG18886.1 - 0.03 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGG18886.1 - 0.031 14.5 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGG18886.1 - 0.04 14.4 0.1 0.069 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGG18886.1 - 0.043 14.2 0.4 0.18 12.2 0.4 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGG18886.1 - 0.048 13.6 0.1 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EGG18886.1 - 0.052 14.1 0.0 0.097 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGG18886.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EGG18886.1 - 0.083 12.6 0.1 0.23 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGG18886.1 - 0.088 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EGG18886.1 - 0.11 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 EGG18886.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 EGG18886.1 - 0.2 11.6 0.5 0.69 9.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC2_membrane PF01061.24 EGG18887.1 - 4.2e-42 143.9 21.8 4.2e-42 143.9 21.8 4.0 3 1 2 5 5 3 1 ABC-2 type transporter ABC_tran PF00005.27 EGG18887.1 - 8.6e-25 87.9 0.0 1.4e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGG18887.1 - 1.6e-05 24.8 0.1 0.15 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGG18887.1 - 0.00036 20.5 0.0 0.00085 19.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGG18887.1 - 0.00091 18.9 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGG18887.1 - 0.0017 17.8 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EGG18887.1 - 0.0067 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain PDR_CDR PF06422.12 EGG18887.1 - 0.0077 16.1 0.3 0.0077 16.1 0.3 5.1 5 0 0 5 5 5 2 CDR ABC transporter AAA_16 PF13191.6 EGG18887.1 - 0.008 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG18887.1 - 0.021 15.1 0.1 0.058 13.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGG18887.1 - 0.032 14.8 0.0 0.13 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EGG18887.1 - 0.06 13.6 0.1 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EGG18887.1 - 0.07 13.0 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_33 PF13671.6 EGG18887.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGG18887.1 - 0.14 12.6 0.0 0.98 9.8 0.0 2.3 2 0 0 2 2 2 0 RNA helicase HCNGP PF07818.13 EGG18888.1 - 8.3e-28 96.9 2.1 3.9e-27 94.7 2.1 2.2 1 0 0 1 1 1 1 HCNGP-like protein MAGE PF01454.19 EGG18889.1 - 0.049 13.3 2.0 0.74 9.5 0.3 2.4 2 0 0 2 2 2 0 MAGE family DUF4061 PF13270.6 EGG18890.1 - 1.8e-23 82.6 3.0 2.1e-23 82.4 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) TraG-D_C PF12696.7 EGG18891.1 - 0.0074 16.3 1.8 0.012 15.6 1.8 1.3 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG FSA_C PF10479.9 EGG18891.1 - 0.022 12.9 5.4 0.024 12.8 5.4 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus B277 PF17623.2 EGG18891.1 - 0.091 11.8 2.3 0.11 11.6 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function Macoilin PF09726.9 EGG18891.1 - 0.47 9.0 3.5 0.46 9.0 3.5 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 EGG18891.1 - 5.7 5.1 6.0 6.8 4.8 6.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SSP160 PF06933.11 EGG18891.1 - 6 4.9 17.2 6.8 4.8 17.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SR-25 PF10500.9 EGG18891.1 - 9.7 5.7 15.0 14 5.2 15.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3825 PF12873.7 EGG18892.1 - 1.8e-62 211.0 0.0 3.5e-62 210.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) ANAPC_CDC26 PF10471.9 EGG18893.1 - 0.17 12.7 2.8 0.23 12.3 2.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Alpha_kinase PF02816.18 EGG18895.1 - 1.1e-62 211.4 0.1 1.1e-62 211.4 0.1 3.6 3 0 0 3 3 3 1 Alpha-kinase family ArfGap PF01412.18 EGG18895.1 - 1.9e-07 31.2 3.8 1.9e-07 31.2 3.8 4.4 2 1 2 4 4 4 1 Putative GTPase activating protein for Arf SHOCT PF09851.9 EGG18895.1 - 0.052 13.3 0.6 0.1 12.4 0.6 1.5 1 0 0 1 1 1 0 Short C-terminal domain PhnA_Zn_Ribbon PF08274.12 EGG18895.1 - 0.7 9.9 3.6 1.5 8.8 3.6 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Coiled PF05710.12 EGG18896.1 - 0.026 15.4 0.3 0.029 15.2 0.3 1.1 1 0 0 1 1 1 0 Coiled coil Pyr_redox_2 PF07992.14 EGG18897.1 - 1.9e-48 165.2 0.4 3.7e-48 164.3 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase JAB PF01398.21 EGG18897.1 - 6.8e-29 100.2 0.1 6.1e-28 97.2 0.0 2.5 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGG18897.1 - 6.3e-27 94.2 3.1 6.3e-27 94.2 3.1 2.1 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function AIF_C PF14721.6 EGG18897.1 - 2.5e-20 73.2 0.5 8.2e-15 55.3 0.0 4.3 3 2 1 4 4 4 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox PF00070.27 EGG18897.1 - 7.2e-07 29.7 0.0 7.2e-07 29.7 0.0 2.9 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGG18897.1 - 2.9e-05 23.6 0.0 4.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EGG18897.1 - 0.00033 20.7 2.0 0.26 11.3 0.0 3.9 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EGG18897.1 - 0.0084 16.5 0.4 0.19 12.2 0.0 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding HI0933_like PF03486.14 EGG18897.1 - 0.035 12.8 7.7 0.05 12.3 0.0 3.9 4 0 0 4 4 4 0 HI0933-like protein POM121 PF15229.6 EGG18897.1 - 0.29 10.7 10.7 0.64 9.6 10.7 1.6 1 0 0 1 1 1 0 POM121 family Band_3_cyto PF07565.13 EGG18897.1 - 1.1 9.0 5.9 0.31 10.8 1.0 2.3 3 0 0 3 3 3 0 Band 3 cytoplasmic domain ThiF PF00899.21 EGG18898.1 - 5.9e-26 91.3 0.3 1e-25 90.5 0.3 1.3 1 1 0 1 1 1 1 ThiF family RRM_1 PF00076.22 EGG18899.1 - 2.8e-42 142.4 1.0 1e-17 63.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG18899.1 - 2 8.3 4.5 21 5.1 0.0 3.8 4 1 0 4 4 4 0 Occluded RNA-recognition motif Solute_trans_a PF03619.16 EGG18900.1 - 1.1e-65 221.9 17.7 1.3e-65 221.5 17.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha ORC6 PF05460.13 EGG18901.1 - 0.37 10.0 16.5 0.54 9.5 16.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) JUPITER PF17054.5 EGG18901.1 - 0.98 8.8 6.3 1.7 8.0 6.3 1.4 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter SR-25 PF10500.9 EGG18901.1 - 1.3 8.6 24.7 0.8 9.3 21.1 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Codanin-1_C PF15296.6 EGG18901.1 - 7.3 6.7 8.0 17 5.5 8.0 1.5 1 0 0 1 1 1 0 Codanin-1 C-terminus PRP38 PF03371.15 EGG18904.1 - 1.7e-54 184.3 0.1 2.3e-54 183.9 0.1 1.2 1 0 0 1 1 1 1 PRP38 family PNISR PF15996.5 EGG18904.1 - 2 8.7 14.5 2.5 8.3 14.5 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CDC45 PF02724.14 EGG18904.1 - 3.5 5.8 28.7 4.9 5.3 28.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGG18904.1 - 8.4 4.5 37.7 10 4.2 37.7 1.1 1 0 0 1 1 1 0 Nop14-like family PH PF00169.29 EGG18905.1 - 1.9e-20 73.4 1.4 3.8e-20 72.4 1.4 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGG18905.1 - 7.7e-08 32.7 5.6 3.8e-07 30.5 5.6 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EGG18905.1 - 0.0053 17.0 1.1 0.0053 17.0 1.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 EGG18905.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.10 EGG18905.1 - 0.15 12.4 1.8 0.15 12.4 0.2 1.8 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_9 PF15410.6 EGG18905.1 - 0.17 12.3 1.5 2.5 8.5 1.5 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain GIDA PF01134.22 EGG18906.1 - 5.1e-153 509.8 0.0 8.6e-153 509.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EGG18906.1 - 1.2e-68 231.5 0.0 1.9e-68 230.8 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EGG18906.1 - 7.6e-05 22.2 0.9 0.00012 21.6 0.9 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EGG18906.1 - 0.0007 18.9 0.0 0.0085 15.4 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EGG18906.1 - 0.0017 17.6 5.6 0.044 13.0 5.6 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGG18906.1 - 0.0031 16.3 3.3 0.43 9.2 1.0 3.0 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 EGG18906.1 - 0.017 14.2 8.0 0.017 14.2 2.3 2.5 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_3 PF13738.6 EGG18906.1 - 0.19 11.0 1.1 4 6.6 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SMC_N PF02463.19 EGG18907.1 - 2e-52 177.8 46.5 6.9e-52 176.0 46.5 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGG18907.1 - 1.1e-17 64.4 0.1 4.3e-17 62.5 0.1 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EGG18907.1 - 1.5e-17 64.7 3.4 1.5e-17 64.7 3.4 7.6 2 2 4 6 6 2 1 AAA domain AAA_21 PF13304.6 EGG18907.1 - 8e-10 39.0 20.0 2.5e-05 24.3 0.2 4.0 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGG18907.1 - 9.1e-08 32.2 21.3 9.1e-08 32.2 21.3 5.3 2 2 1 4 4 3 1 AAA ATPase domain Spc7 PF08317.11 EGG18907.1 - 9.9e-07 27.9 13.0 9.9e-07 27.9 13.0 6.7 3 2 4 7 7 7 3 Spc7 kinetochore protein AAA_29 PF13555.6 EGG18907.1 - 2.6e-05 23.9 0.0 6.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Laminin_II PF06009.12 EGG18907.1 - 5.3e-05 23.3 3.4 5.3e-05 23.3 3.4 8.0 4 2 3 8 8 8 2 Laminin Domain II ABC_tran PF00005.27 EGG18907.1 - 0.00029 21.4 0.6 0.0038 17.7 0.1 6.7 4 2 0 4 4 2 2 ABC transporter DUF1664 PF07889.12 EGG18907.1 - 0.00077 19.5 2.9 0.00077 19.5 2.9 8.6 4 2 4 9 9 9 3 Protein of unknown function (DUF1664) DUF745 PF05335.13 EGG18907.1 - 0.0022 17.7 9.1 0.0022 17.7 9.1 6.5 2 2 5 7 7 5 1 Protein of unknown function (DUF745) TPR_MLP1_2 PF07926.12 EGG18907.1 - 0.0023 18.0 12.5 0.0023 18.0 12.5 7.6 4 3 3 7 7 6 1 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 EGG18907.1 - 0.0031 17.7 9.2 0.0031 17.7 9.2 10.1 5 3 5 11 11 9 2 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 EGG18907.1 - 0.0065 16.5 20.5 0.0065 16.5 20.5 7.6 4 2 4 8 8 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 EGG18907.1 - 0.0076 16.3 1.8 0.0076 16.3 1.8 8.9 5 2 3 9 9 6 1 BRE1 E3 ubiquitin ligase Cep57_CLD_2 PF14197.6 EGG18907.1 - 0.0087 16.1 6.7 0.0087 16.1 6.7 6.6 7 1 1 8 8 5 1 Centrosome localisation domain of PPC89 DUF3584 PF12128.8 EGG18907.1 - 0.021 12.4 98.9 0.0026 15.4 39.2 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF3584) FPRL1_inhibitor PF16104.5 EGG18907.1 - 8.7 6.5 11.7 3.6 7.8 1.8 3.9 2 1 1 3 3 3 0 Formyl peptide receptor-like 1 inhibitory protein SAM_2 PF07647.17 EGG18908.1 - 1.2e-07 31.8 0.1 0.00014 21.9 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 EGG18908.1 - 1.1e-05 25.6 0.2 0.16 12.2 0.1 2.7 2 0 0 2 2 2 2 Ste50p, sterile alpha motif SAM_1 PF00536.30 EGG18908.1 - 0.00062 20.2 0.2 0.015 15.7 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) AAA_16 PF13191.6 EGG18908.1 - 0.067 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 EGG18908.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 KaiC FSA_C PF10479.9 EGG18908.1 - 0.22 9.6 7.8 0.32 9.1 7.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Peptidase_C48 PF02902.19 EGG18909.1 - 1.3e-07 31.7 0.1 1.6e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.18 EGG18909.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.4 1 1 0 1 1 1 0 Adenovirus endoprotease Pox_A32 PF04665.12 EGG18912.1 - 5.6e-06 26.0 0.1 7.3e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_10 PF12846.7 EGG18912.1 - 0.0046 15.9 0.2 0.017 14.1 0.0 1.7 1 1 1 2 2 2 1 AAA-like domain zf-RVT PF13966.6 EGG18913.1 - 0.0048 17.6 0.0 0.018 15.7 0.0 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase BppL_N PF18338.1 EGG18913.1 - 0.015 15.1 0.1 0.066 13.0 0.0 2.1 2 0 0 2 2 2 0 Lower baseplate protein N-terminal domain ATE_C PF04377.15 EGG18915.1 - 3e-50 170.3 4.9 3e-50 170.3 4.9 1.9 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EGG18915.1 - 3.1e-24 85.2 2.6 7.5e-24 83.9 2.6 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DHR-2 PF06920.13 EGG18916.1 - 1.2e-143 479.6 17.2 1.2e-143 479.6 17.2 1.7 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 EGG18916.1 - 2.1e-28 99.5 6.7 2.7e-26 92.6 6.7 2.9 1 1 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins LRR_4 PF12799.7 EGG18918.1 - 0.015 15.7 15.3 11 6.6 0.1 6.3 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Nop14 PF04147.12 EGG18918.1 - 0.11 10.7 22.6 0.16 10.2 22.6 1.2 1 0 0 1 1 1 0 Nop14-like family LRR_4 PF12799.7 EGG18919.1 - 8.7e-06 26.0 14.1 0.029 14.8 0.7 5.6 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) Rho_N PF07498.12 EGG18919.1 - 0.0068 16.3 3.4 0.018 15.0 3.4 1.8 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain PBP1_TM PF14812.6 EGG18919.1 - 0.012 16.0 16.0 0.012 16.0 16.0 3.6 2 1 2 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WIYLD PF10440.9 EGG18919.1 - 0.025 14.4 0.1 13 5.7 0.0 3.0 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain SURF2 PF05477.11 EGG18919.1 - 0.066 12.9 21.5 0.13 12.0 21.5 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) LRR_8 PF13855.6 EGG18919.1 - 0.25 11.1 6.6 3.9 7.3 0.1 4.3 4 0 0 4 4 4 0 Leucine rich repeat BUD22 PF09073.10 EGG18919.1 - 0.8 9.0 23.4 1.9 7.7 23.4 1.5 1 0 0 1 1 1 0 BUD22 Colicin PF01024.19 EGG18919.1 - 1.8 8.4 6.7 59 3.5 3.2 3.3 3 0 0 3 3 3 0 Colicin pore forming domain DUF2992 PF11208.8 EGG18919.1 - 4.5 7.5 9.6 0.31 11.3 3.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2992) Cadherin_C_2 PF16492.5 EGG18920.1 - 0.058 14.1 0.1 0.085 13.6 0.1 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Leg1 PF05612.12 EGG18920.1 - 0.062 12.4 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Leg1 Ins134_P3_kin PF05770.11 EGG18922.1 - 1.8e-45 155.0 1.0 2.5e-45 154.5 1.0 1.2 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 EGG18922.1 - 0.00053 20.3 0.5 0.0032 17.8 0.1 2.6 3 1 0 3 3 3 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain 4HBT PF03061.22 EGG18923.1 - 5.4e-08 33.1 0.0 8.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily BTB PF00651.31 EGG18924.1 - 2.4e-14 53.5 4.6 3.1e-14 53.2 0.8 3.0 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 EGG18924.1 - 3.2e-09 36.8 5.6 8.7e-08 32.2 0.3 2.8 3 0 0 3 3 3 2 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 EGG18924.1 - 6.1e-06 26.4 0.1 6.1e-06 26.4 0.1 2.8 3 0 0 3 3 3 1 F5/8 type C domain Sad1_UNC PF07738.13 EGG18924.1 - 0.00044 20.3 0.2 0.0015 18.5 0.0 2.0 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Aldedh PF00171.22 EGG18925.1 - 9.2e-100 334.3 0.0 1.1e-99 334.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-3CxxC PF13695.6 EGG18925.1 - 0.13 12.7 0.3 0.61 10.6 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding domain VWA_3 PF13768.6 EGG18926.1 - 0.00024 21.1 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EGG18926.1 - 0.00065 20.0 0.1 0.073 13.3 0.1 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Erf4 PF10256.9 EGG18926.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family vWA-TerF-like PF10138.9 EGG18926.1 - 0.0063 16.6 0.1 0.12 12.4 0.1 2.1 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.6 EGG18926.1 - 0.0085 16.7 0.0 0.32 11.7 0.0 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.16 EGG18926.1 - 0.025 14.1 0.1 0.037 13.5 0.1 1.2 1 0 0 1 1 1 0 Copine DUF3449 PF11931.8 EGG18930.1 - 2.3e-62 210.1 5.9 2.3e-62 210.1 5.9 3.5 3 1 0 3 3 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EGG18930.1 - 3.1e-21 75.7 5.6 3.1e-21 75.7 5.6 2.7 3 0 0 3 3 3 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-met PF12874.7 EGG18930.1 - 1.3e-10 41.3 9.5 9.9e-09 35.3 1.8 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.8 EGG18930.1 - 1.1e-09 38.0 0.4 1.1e-09 38.0 0.4 2.2 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 EGG18930.1 - 1.1e-05 25.6 1.3 1.1e-05 25.6 1.3 3.3 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGG18930.1 - 1.5e-05 25.3 2.2 0.0073 16.6 0.3 2.9 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) BSP_II PF05432.11 EGG18930.1 - 0.011 15.4 12.5 0.011 15.4 12.5 2.6 3 0 0 3 3 2 0 Bone sialoprotein II (BSP-II) zf-C2H2_4 PF13894.6 EGG18930.1 - 0.023 15.5 6.3 2.6 9.1 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Autophagy_act_C PF03987.15 EGG18930.1 - 0.13 12.8 0.2 0.4 11.3 0.2 1.9 1 0 0 1 1 1 0 Autophagocytosis associated protein, active-site domain zf-C2H2_11 PF16622.5 EGG18930.1 - 0.13 12.0 0.3 0.41 10.5 0.3 1.8 1 0 0 1 1 1 0 zinc-finger C2H2-type Desulfoferrod_N PF06397.12 EGG18930.1 - 0.2 11.3 0.5 0.44 10.2 0.5 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain zf-C2H2 PF00096.26 EGG18930.1 - 1.3 9.6 9.8 0.38 11.3 0.9 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF2175 PF09943.9 EGG18930.1 - 4 7.8 8.0 6.1 7.2 0.2 4.0 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) QRPTase_C PF01729.19 EGG18932.1 - 1e-55 188.1 0.1 1.4e-55 187.7 0.1 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EGG18932.1 - 4.2e-17 62.0 0.0 1.1e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain zf-C2H2_jaz PF12171.8 EGG18933.1 - 5.5e-09 36.1 0.2 1.3e-08 34.8 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG18933.1 - 1.2e-06 28.7 0.3 2.1e-06 27.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 EGG18933.1 - 1.2e-05 25.2 15.6 0.0023 18.0 1.1 3.3 3 0 0 3 3 3 2 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2_2 PF12756.7 EGG18933.1 - 0.02 15.2 0.7 0.055 13.8 0.0 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EGG18933.1 - 0.096 13.6 0.2 0.18 12.7 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Cellulose_synt PF03552.14 EGG18933.1 - 2.6 6.4 24.1 0.85 8.0 9.8 2.1 1 1 1 2 2 2 0 Cellulose synthase DUF2868 PF11067.8 EGG18933.1 - 3.3 7.1 6.3 1.5 8.3 3.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) DUF4746 PF15928.5 EGG18933.1 - 3.3 7.0 36.9 1.5 8.2 17.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4746) Myc_N PF01056.18 EGG18933.1 - 3.7 7.3 24.2 0.2 11.5 3.6 2.2 2 0 0 2 2 2 0 Myc amino-terminal region G8 PF10162.9 EGG18934.1 - 9.6e-23 80.6 0.0 2.8e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 G8 domain ABC2_membrane PF01061.24 EGG18935.1 - 4.2e-37 127.6 25.4 4.2e-37 127.6 25.4 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGG18935.1 - 7.5e-27 94.5 0.0 1.7e-26 93.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGG18935.1 - 8.4e-07 29.1 0.7 0.022 14.6 0.2 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG18935.1 - 0.003 17.0 0.1 0.43 10.0 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EGG18935.1 - 0.0037 17.8 0.0 0.0069 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG18935.1 - 0.004 17.6 0.0 0.0074 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG18935.1 - 0.0045 17.3 0.1 0.033 14.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGG18935.1 - 0.01 15.5 0.2 0.022 14.5 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RecA PF00154.21 EGG18935.1 - 0.034 13.6 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_23 PF13476.6 EGG18935.1 - 0.047 14.2 0.1 0.1 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGG18935.1 - 0.047 13.6 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 EGG18935.1 - 0.048 12.7 0.2 0.078 12.0 0.2 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EGG18935.1 - 0.05 13.5 0.3 0.12 12.3 0.3 1.5 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 EGG18935.1 - 0.079 13.2 0.0 0.95 9.7 0.0 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PDR_CDR PF06422.12 EGG18935.1 - 0.088 12.7 0.4 0.59 10.1 0.0 2.7 3 0 0 3 3 3 0 CDR ABC transporter cobW PF02492.19 EGG18935.1 - 0.095 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EGG18935.1 - 0.15 12.5 0.0 0.86 10.0 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGG18935.1 - 0.18 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGG18935.1 - 0.22 11.8 0.1 0.35 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain SQHop_cyclase_C PF13243.6 EGG18936.1 - 1.4e-59 201.8 0.0 7e-52 176.5 0.0 2.7 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGG18936.1 - 1.2e-46 159.2 0.0 1.4e-40 139.2 0.0 4.2 3 1 3 6 6 5 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EGG18936.1 - 2.4e-40 136.0 1.6 1.7e-09 37.2 0.5 6.6 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Tweety PF04906.13 EGG18936.1 - 3.8e-07 29.1 5.0 6.1e-05 21.9 3.3 2.8 2 1 1 3 3 3 2 Tweety Pec_lyase PF09492.10 EGG18936.1 - 2.2e-05 24.0 0.0 0.13 11.5 0.0 3.9 3 1 0 4 4 4 2 Pectic acid lyase DUF2207 PF09972.9 EGG18936.1 - 0.00011 21.2 8.0 0.062 12.1 1.6 2.8 2 1 1 3 3 3 2 Predicted membrane protein (DUF2207) TED_complement PF07678.14 EGG18936.1 - 0.00046 19.3 0.0 6.6 5.7 0.0 4.2 2 1 2 4 4 4 2 A-macroglobulin TED domain MRNIP PF15749.5 EGG18937.1 - 3.6e-27 95.2 20.5 3.6e-27 95.2 20.5 4.1 4 1 0 4 4 4 1 MRN-interacting protein CTP_transf_1 PF01148.20 EGG18938.1 - 2.8e-65 220.7 23.1 4.2e-65 220.2 23.1 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family DUF755 PF05501.11 EGG18942.1 - 1.3 9.3 22.1 1.4 9.2 22.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) LYRIC PF15686.5 EGG18942.1 - 5 6.6 15.8 5 6.6 15.8 1.0 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF1741 PF08427.10 EGG18943.1 - 0.009 15.7 7.9 0.013 15.1 7.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) MTBP_C PF14920.6 EGG18943.1 - 0.015 15.1 10.0 0.023 14.4 10.0 1.2 1 0 0 1 1 1 0 MDM2-binding DUF5624 PF18538.1 EGG18943.1 - 0.38 10.9 4.3 0.63 10.1 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Exonuc_VII_L PF02601.15 EGG18943.1 - 0.48 9.9 10.5 0.59 9.7 10.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3139 PF11337.8 EGG18943.1 - 0.7 10.6 0.1 0.7 10.6 0.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF3139) LMBR1 PF04791.16 EGG18943.1 - 1.5 7.7 12.2 2 7.2 12.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CAP59_mtransfer PF11735.8 EGG18943.1 - 2.6 7.7 7.3 4.9 6.8 7.3 1.4 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Tweety PF04906.13 EGG18943.1 - 3.2 6.3 6.7 4.8 5.7 6.7 1.2 1 0 0 1 1 1 0 Tweety DUF4407 PF14362.6 EGG18943.1 - 6.5 6.0 13.3 9.9 5.4 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PDR_CDR PF06422.12 EGG18944.1 - 3.7e-06 26.7 0.0 8.9e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane PF01061.24 EGG18944.1 - 0.00058 19.3 0.3 0.00058 19.3 0.3 1.7 2 0 0 2 2 2 1 ABC-2 type transporter Wzz PF02706.15 EGG18944.1 - 0.0013 19.0 0.6 0.03 14.6 0.1 2.5 2 0 0 2 2 2 1 Chain length determinant protein C1_1 PF00130.22 EGG18944.1 - 0.32 10.9 6.5 0.64 9.9 6.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 EGG18944.1 - 6.4 6.4 9.9 0.12 11.9 2.8 1.7 2 0 0 2 2 2 0 PHD-finger DDE_Tnp_1_7 PF13843.6 EGG18945.1 - 1.4e-22 80.5 0.2 1.4e-20 73.9 0.0 2.4 2 0 0 2 2 2 1 Transposase IS4 Pex14_N PF04695.13 EGG18945.1 - 0.003 18.2 13.9 0.082 13.6 1.7 2.4 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region VESA1_N PF12785.7 EGG18945.1 - 0.026 13.5 10.8 0.049 12.6 10.1 1.7 1 1 1 2 2 2 0 Variant erythrocyte surface antigen-1 DUF2052 PF09747.9 EGG18945.1 - 0.029 14.5 19.3 0.038 14.1 18.1 1.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Apt1 PF10351.9 EGG18945.1 - 0.053 12.4 15.4 0.057 12.3 2.5 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain RNA12 PF10443.9 EGG18945.1 - 0.072 11.8 5.4 0.18 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA12 protein FAM176 PF14851.6 EGG18945.1 - 0.12 12.0 13.0 0.22 11.2 10.9 2.4 3 0 0 3 3 3 0 FAM176 family RED_N PF07808.13 EGG18945.1 - 0.14 11.7 10.5 0.25 10.9 10.5 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF3408 PF11888.8 EGG18945.1 - 0.19 11.8 15.9 1.7 8.8 13.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) CDC45 PF02724.14 EGG18945.1 - 0.19 10.0 11.7 0.32 9.3 11.7 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.6 EGG18945.1 - 0.47 10.7 9.2 1.8 8.9 9.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TAFII55_N PF04658.13 EGG18945.1 - 0.88 9.3 6.8 1.5 8.5 6.1 1.7 2 0 0 2 2 2 0 TAFII55 protein conserved region CCDC53 PF10152.9 EGG18945.1 - 0.91 9.9 11.6 3.6 8.0 7.9 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Tim54 PF11711.8 EGG18945.1 - 0.94 8.2 11.0 0.69 8.6 7.3 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF3306 PF11748.8 EGG18945.1 - 4.1 8.3 13.0 0.78 10.6 8.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) EBP50_C PF09007.11 EGG18945.1 - 5.3 8.0 21.5 3.6 8.6 6.4 2.4 2 0 0 2 2 2 0 EBP50, C-terminal Ycf66_N PF07444.11 EGG18947.1 - 0.015 15.4 1.8 0.21 11.8 0.1 2.3 1 1 1 2 2 2 0 Ycf66 protein N-terminus ABC_tran PF00005.27 EGG18950.1 - 1.3e-25 90.5 0.4 1.3e-24 87.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 EGG18950.1 - 1.3e-09 37.8 8.2 2.1e-09 37.1 8.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 EGG18950.1 - 4.3e-07 30.1 0.2 0.0069 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG18950.1 - 0.0024 17.3 0.0 0.13 11.7 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGG18950.1 - 0.0033 17.8 0.0 0.0055 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGG18950.1 - 0.0042 16.8 0.9 0.014 15.2 0.9 1.9 1 1 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 EGG18950.1 - 0.012 15.5 0.1 3.2 7.6 0.1 2.6 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 EGG18950.1 - 0.012 15.5 0.0 0.052 13.5 0.0 2.0 1 1 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGG18950.1 - 0.016 15.1 0.2 0.049 13.5 0.1 1.8 1 1 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EGG18950.1 - 0.034 14.7 0.0 0.069 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGG18950.1 - 0.042 14.1 0.1 0.15 12.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGG18950.1 - 0.1 13.1 0.5 0.1 13.1 0.5 2.6 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EGG18950.1 - 0.11 13.0 0.1 0.5 10.8 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGG18950.1 - 0.12 12.1 0.2 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGG18950.1 - 0.28 11.2 1.7 25 4.9 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain Zip PF02535.22 EGG18951.1 - 0.041 13.1 4.3 0.093 11.9 4.3 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter Phage_holin_3_6 PF07332.11 EGG18951.1 - 5.5 7.1 6.9 0.58 10.2 0.6 2.3 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III BRCT_2 PF16589.5 EGG18952.1 - 1.1e-07 32.1 0.1 2.7e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG18952.1 - 1.9e-05 24.9 0.1 5.1e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGG18952.1 - 0.00093 19.1 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain FRQ PF09421.10 EGG18952.1 - 0.013 13.6 1.5 0.018 13.1 1.5 1.1 1 0 0 1 1 1 0 Frequency clock protein UDPG_MGDP_dh_N PF03721.14 EGG18952.1 - 0.05 13.2 0.4 0.11 12.0 0.4 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gtr1_RagA PF04670.12 EGG18953.1 - 7.9e-71 238.1 4.9 1e-70 237.7 4.9 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EGG18953.1 - 3.7e-07 29.8 0.1 6.2e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG18953.1 - 1.6e-06 28.3 0.1 2.8e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGG18953.1 - 1.8e-05 24.3 0.1 2.8e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGG18953.1 - 2.5e-05 23.9 0.4 3.6e-05 23.4 0.4 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGG18953.1 - 0.00043 20.4 0.1 0.0021 18.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Stirrup PF09061.6 EGG18953.1 - 0.076 13.2 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Stirrup Solute_trans_a PF03619.16 EGG18954.1 - 8.3e-86 287.8 21.1 8.3e-86 287.8 21.1 2.3 2 1 1 3 3 3 1 Organic solute transporter Ostalpha Na_Ca_ex PF01699.24 EGG18954.1 - 2.5e-17 63.2 30.4 6e-13 49.0 13.0 4.2 4 0 0 4 4 4 2 Sodium/calcium exchanger protein GYF PF02213.16 EGG18955.1 - 1.9e-15 56.2 0.4 4.6e-15 55.0 0.4 1.7 1 0 0 1 1 1 1 GYF domain Lung_7-TM_R PF06814.13 EGG18956.1 - 0.0038 16.5 1.6 0.004 16.4 1.6 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor Ndc1_Nup PF09531.10 EGG18956.1 - 0.52 8.9 4.1 0.53 8.9 4.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ATP_synt_H PF05493.13 EGG18956.1 - 1.7 9.1 6.6 2.4 8.7 5.2 2.1 1 1 1 2 2 2 0 ATP synthase subunit H Myb_Cef PF11831.8 EGG18957.1 - 1e-27 97.2 33.2 1e-27 97.2 33.2 3.4 3 1 1 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EGG18957.1 - 1.3e-17 63.7 3.7 3.2e-09 36.8 0.4 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG18957.1 - 1.4e-14 54.1 3.8 1.4e-11 44.4 1.6 3.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain FPN1 PF06963.12 EGG18957.1 - 0.27 9.8 2.7 0.49 8.9 2.7 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF1515 PF07439.11 EGG18957.1 - 0.33 11.0 5.9 1.1 9.4 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) CobU PF02283.16 EGG18957.1 - 1.2 8.7 6.1 3.6 7.1 5.8 2.0 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase SANT_DAMP1_like PF16282.5 EGG18957.1 - 5.3 7.3 7.6 0.59 10.4 0.1 3.0 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Peptidase_M20 PF01546.28 EGG18958.1 - 1.5e-19 70.5 0.1 1.8e-19 70.2 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGG18958.1 - 5.7e-10 39.1 0.1 1e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain PigN PF04987.14 EGG18959.1 - 9.1e-124 413.8 39.6 9.1e-124 413.8 39.6 1.6 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EGG18959.1 - 2.4e-10 40.6 0.2 2.2e-07 30.8 0.2 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGG18959.1 - 3e-06 26.9 0.5 1.1e-05 25.1 0.1 2.1 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 EGG18959.1 - 0.03 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Zip PF02535.22 EGG18959.1 - 0.089 12.0 6.1 1 8.5 6.1 2.5 2 0 0 2 2 2 0 ZIP Zinc transporter Semialdhyde_dhC PF02774.18 EGG18960.1 - 1.9e-30 106.3 0.0 2.7e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EGG18960.1 - 3e-29 101.9 0.1 4.7e-29 101.3 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EGG18960.1 - 1.9e-05 24.8 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 EGG18960.1 - 0.00046 20.4 0.0 0.00077 19.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 EGG18960.1 - 0.0037 18.0 0.7 0.0065 17.2 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Gp_dh_C PF02800.20 EGG18960.1 - 0.005 16.4 0.1 0.04 13.5 0.0 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Ldh_1_N PF00056.23 EGG18960.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Ank_2 PF12796.7 EGG18961.1 - 3e-09 37.4 2.4 0.00026 21.5 0.2 4.5 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG18961.1 - 8.4e-05 22.8 0.1 12 6.3 0.0 4.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG18961.1 - 0.0013 19.0 0.2 9.9 7.1 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 EGG18961.1 - 0.0015 19.0 3.6 0.068 13.8 0.0 4.5 3 1 2 5 5 5 1 Ankyrin repeats (many copies) DUF2457 PF10446.9 EGG18961.1 - 5.8 5.9 18.2 8.2 5.4 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Amidohydro_2 PF04909.14 EGG18962.1 - 2.6e-61 207.9 0.0 3e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Acyl-CoA_dh_N PF02771.16 EGG18962.1 - 0.11 13.1 0.0 0.23 12.2 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Rho_N PF07498.12 EGG18964.1 - 7.8e-05 22.5 1.1 0.00012 21.9 1.1 1.3 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain DKNYY PF13644.6 EGG18964.1 - 0.085 13.6 0.3 0.1 13.4 0.3 1.1 1 0 0 1 1 1 0 DKNYY family LRR_4 PF12799.7 EGG18965.1 - 0.054 13.9 2.3 0.24 11.9 1.3 2.4 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) HSF_DNA-bind PF00447.17 EGG18966.1 - 5.3e-20 71.8 0.8 5.3e-20 71.8 0.8 3.6 2 2 0 2 2 1 1 HSF-type DNA-binding SdrD_B PF17210.3 EGG18966.1 - 4.3e-12 46.2 2.5 2e-08 34.5 0.3 4.8 5 1 0 5 5 4 2 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG18966.1 - 5.2e-11 42.7 0.9 5.2e-11 42.7 0.9 4.5 3 1 0 3 3 2 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 EGG18966.1 - 2.2e-06 27.6 0.6 2.2e-06 27.6 0.6 5.2 5 1 0 5 5 4 1 Bacterial Ig-like domain (group 1) CarbopepD_reg_2 PF13715.6 EGG18966.1 - 2.7e-05 24.1 0.1 2.7e-05 24.1 0.1 2.6 2 0 0 2 2 1 1 CarboxypepD_reg-like domain fn3_3 PF14686.6 EGG18966.1 - 0.0037 17.0 0.3 0.015 15.0 0.3 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II ZapB PF06005.12 EGG18966.1 - 0.01 16.2 2.1 0.01 16.2 2.1 2.8 2 1 0 2 2 1 0 Cell division protein ZapB phage_tail_N PF08400.10 EGG18966.1 - 0.019 15.0 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Prophage tail fibre N-terminal SpaA PF17802.1 EGG18966.1 - 0.024 15.0 11.0 0.55 10.6 0.2 3.6 3 1 0 3 3 3 0 Prealbumin-like fold domain DUF4198 PF10670.9 EGG18966.1 - 0.031 14.6 0.5 0.094 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4198) TFIIA PF03153.13 EGG18966.1 - 0.22 11.5 38.2 0.39 10.7 38.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EF-G-binding_N PF07299.11 EGG18966.1 - 0.95 10.0 7.8 0.64 10.6 5.3 2.1 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Hid1 PF12722.7 EGG18966.1 - 3.6 5.6 16.9 6 4.9 16.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 EGG18966.1 - 7.7 3.5 16.2 11 2.9 16.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PDZ_3 PF17815.1 EGG18967.1 - 4.2e-38 130.5 0.2 6.4e-38 129.9 0.2 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 EGG18967.1 - 5e-21 76.2 0.2 1.1e-20 75.0 0.0 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGG18967.1 - 7.5e-15 55.3 0.0 2.1e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Trypsin PDZ_2 PF13180.6 EGG18967.1 - 2.3e-07 31.0 0.1 6e-06 26.5 0.0 2.7 2 0 0 2 2 2 1 PDZ domain CCDC106 PF15794.5 EGG18967.1 - 8.1 6.1 7.6 13 5.4 7.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DARPP-32 PF05395.12 EGG18969.1 - 0.0071 16.6 0.2 0.0075 16.5 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 DUF1057 PF06342.12 EGG18969.1 - 0.049 12.7 2.1 0.056 12.5 2.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF2388 PF09498.10 EGG18969.1 - 0.12 12.3 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) Nucleoporin_N PF08801.11 EGG18970.1 - 2.5e-48 164.9 10.6 6.8e-48 163.5 10.6 1.8 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EGG18970.1 - 6.4e-11 41.7 20.5 6.4e-11 41.7 20.5 2.1 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF4660 PF15559.6 EGG18970.1 - 0.064 13.6 4.7 0.41 11.0 4.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) Peptidase_S49_N PF08496.10 EGG18970.1 - 3.6 7.6 7.6 11 6.1 7.6 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Phosphorylase PF00343.20 EGG18971.1 - 0 1045.0 0.2 0 1044.4 0.2 1.3 1 0 0 1 1 1 1 Carbohydrate phosphorylase Methyltransf_23 PF13489.6 EGG18971.1 - 1.5e-19 70.5 0.0 3e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG18971.1 - 0.024 15.3 0.0 0.083 13.6 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGG18971.1 - 0.08 12.7 0.1 6.2 6.6 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGG18971.1 - 0.44 11.3 5.1 8.1 7.3 0.0 3.5 2 1 0 2 2 2 0 Methyltransferase domain zf-Mss51 PF13824.6 EGG18971.1 - 0.46 10.6 2.7 1.5 9.0 2.7 2.0 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 EPL1 PF10513.9 EGG18971.1 - 1.8 8.9 20.0 1.2 9.5 3.2 3.3 3 0 0 3 3 3 0 Enhancer of polycomb-like Herpes_UL6 PF01763.16 EGG18972.1 - 0.0027 16.3 4.8 0.0029 16.2 4.8 1.0 1 0 0 1 1 1 1 Herpesvirus UL6 like DYW_deaminase PF14432.6 EGG18972.1 - 0.039 13.8 1.1 0.042 13.7 1.1 1.1 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases SR-25 PF10500.9 EGG18972.1 - 0.093 12.3 23.2 0.12 12.0 23.2 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Prominin PF05478.11 EGG18972.1 - 0.094 10.7 7.6 0.093 10.7 7.6 1.0 1 0 0 1 1 1 0 Prominin DUF3446 PF11928.8 EGG18972.1 - 0.1 12.9 17.7 0.15 12.3 17.7 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain CAP_N PF01213.19 EGG18972.1 - 0.29 10.6 8.2 0.3 10.5 8.2 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EBP50_C PF09007.11 EGG18972.1 - 0.88 10.6 10.5 1.1 10.3 10.5 1.1 1 0 0 1 1 1 0 EBP50, C-terminal SUZ PF12752.7 EGG18972.1 - 1.4 9.8 7.4 0.75 10.6 5.6 1.5 2 0 0 2 2 2 0 SUZ domain Corona_nucleoca PF00937.18 EGG18972.1 - 5 6.0 11.8 5 6.0 11.8 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein XhlA PF10779.9 EGG18972.1 - 6.3 7.1 7.0 5.5 7.3 3.7 2.0 1 1 2 3 3 3 0 Haemolysin XhlA SMYLE_N PF18615.1 EGG18972.1 - 6.8 6.1 11.1 7.2 6.1 11.1 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Cytidylate_kin PF02224.18 EGG18973.1 - 0.00024 20.9 1.3 0.031 14.0 0.0 2.9 2 1 1 3 3 3 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 EGG18973.1 - 0.0006 20.0 4.5 0.014 15.5 2.4 2.6 3 0 0 3 3 3 1 Cytidylate kinase-like family AAA_18 PF13238.6 EGG18973.1 - 0.0013 19.3 1.1 0.0072 16.9 0.3 2.5 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.10 EGG18973.1 - 0.0069 15.9 0.0 0.022 14.2 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 EGG18973.1 - 0.0076 16.7 0.0 0.046 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain CPT PF07931.12 EGG18973.1 - 0.022 14.6 0.8 2 8.2 0.0 2.7 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 EGG18973.1 - 0.027 14.9 0.1 0.1 13.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGG18973.1 - 0.059 12.5 0.0 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Carboxyl_trans PF01039.22 EGG18974.1 - 4.9e-191 635.7 0.3 5.9e-191 635.4 0.3 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain LRR_8 PF13855.6 EGG18975.1 - 4.2e-06 26.4 8.2 0.0057 16.4 0.5 5.0 4 0 0 4 4 4 3 Leucine rich repeat F-box-like PF12937.7 EGG18975.1 - 1.5e-05 24.8 0.4 0.00012 21.9 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGG18975.1 - 6.1e-05 22.8 2.3 0.00029 20.6 0.8 2.9 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 EGG18975.1 - 0.013 15.9 19.0 4.3 7.9 0.3 8.5 6 2 3 9 9 9 0 Leucine Rich repeats (2 copies) Homeobox_KN PF05920.11 EGG18976.1 - 5.3e-13 48.6 0.0 1.1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EGG18976.1 - 4.4e-11 42.5 0.5 4.4e-11 42.5 0.5 2.2 2 0 0 2 2 2 1 Homeodomain PBC PF03792.13 EGG18976.1 - 5.8e-05 22.9 1.2 5.8e-05 22.9 1.2 2.1 2 0 0 2 2 2 1 PBC domain Vac14_Fab1_bd PF12755.7 EGG18976.1 - 0.0038 17.8 0.5 0.0072 16.9 0.5 1.5 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region Menin PF05053.13 EGG18976.1 - 0.28 9.5 14.8 0.36 9.2 4.6 2.1 2 0 0 2 2 2 0 Menin SelK_SelG PF10961.8 EGG18976.1 - 2.7 8.7 4.3 17 6.1 0.7 2.5 2 0 0 2 2 2 0 Selenoprotein SelK_SelG 2Fe-2S_thioredx PF01257.19 EGG18977.1 - 5.7e-59 198.1 0.4 7.3e-59 197.8 0.4 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin MtrG PF04210.13 EGG18978.1 - 0.46 10.4 3.2 7.5 6.5 0.2 3.5 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G NTP_transf_2 PF01909.23 EGG18979.1 - 1.9e-06 28.1 0.0 5.8e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EGG18979.1 - 5.6e-06 26.5 0.1 2.4e-05 24.5 0.1 2.2 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 EGG18979.1 - 0.02 15.0 0.0 0.078 13.1 0.0 2.0 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase zf-SNAP50_C PF12251.8 EGG18980.1 - 7e-63 211.9 6.3 7e-63 211.9 6.3 1.7 2 0 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal GAIN_A PF18619.1 EGG18980.1 - 0.061 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A HMG_CoA_synt_N PF01154.17 EGG18981.1 - 1.8e-88 294.9 1.1 3.6e-88 294.0 1.1 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EGG18981.1 - 2.1e-82 276.9 3.4 3.2e-82 276.3 3.4 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF2072 PF09845.9 EGG18981.1 - 0.056 13.7 0.7 0.11 12.8 0.7 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF1084 PF06454.11 EGG18982.1 - 7.7e-10 38.6 5.4 1e-09 38.2 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Glyoxal_oxid_N PF07250.11 EGG18982.1 - 0.052 12.7 0.1 0.095 11.9 0.1 1.4 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus DUF2633 PF11119.8 EGG18982.1 - 1.5 8.8 0.0 1.5 8.8 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2633) TIM PF00121.18 EGG18983.1 - 8.2e-93 310.2 0.5 9.3e-93 310.1 0.5 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase LIM PF00412.22 EGG18984.1 - 4.3e-26 90.9 21.8 2.5e-13 50.0 7.5 2.1 2 0 0 2 2 2 2 LIM domain Mu-like_Com PF10122.9 EGG18984.1 - 0.061 12.8 4.8 8.2 6.0 0.0 3.4 3 0 0 3 3 3 0 Mu-like prophage protein Com zf-ACC PF17848.1 EGG18984.1 - 0.082 13.0 10.7 16 5.7 0.1 4.3 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zf-SNAP50_C PF12251.8 EGG18984.1 - 0.43 10.2 16.0 0.14 11.8 4.7 2.3 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal NMD3 PF04981.13 EGG18984.1 - 0.74 9.2 14.0 0.076 12.5 3.2 2.3 2 1 0 2 2 2 0 NMD3 family DUF2688 PF10892.8 EGG18984.1 - 1.1 8.8 0.0 1.1 8.8 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2688) SR1P PF13790.6 EGG18984.1 - 5.9 7.1 8.6 15 5.8 0.4 3.8 4 0 0 4 4 4 0 SR1 protein A_deamin PF02137.18 EGG18985.1 - 3.7e-76 256.7 0.8 9.4e-76 255.4 0.8 1.6 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain LSM PF01423.22 EGG18985.1 - 1.9e-17 62.7 0.0 4.3e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 LSM domain SH3-RhoG_link PF16609.5 EGG18987.1 - 0.11 12.1 10.7 0.11 12.1 10.7 1.1 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region polyprenyl_synt PF00348.17 EGG18988.1 - 1.9e-90 302.4 0.0 4.1e-90 301.3 0.0 1.6 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.25 EGG18988.1 - 2.7e-69 233.5 0.5 6.5e-69 232.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG18988.1 - 6.2e-54 183.0 0.4 5.8e-53 179.8 0.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase PBD PF00786.28 EGG18988.1 - 0.0017 18.7 0.2 0.013 15.9 0.2 2.7 1 0 0 1 1 1 1 P21-Rho-binding domain BUD22 PF09073.10 EGG18988.1 - 0.0021 17.5 20.9 0.0021 17.5 20.9 4.0 3 1 0 3 3 3 1 BUD22 Metallophos PF00149.28 EGG18989.1 - 6.8e-36 124.7 0.2 1e-35 124.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EGG18989.1 - 0.022 15.1 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 PPP5 TPR repeat region DUF5378 PF17349.2 EGG18989.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Sporozoite_P67 PF05642.11 EGG18989.1 - 1.4 6.9 7.3 2 6.4 7.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myb_DNA-binding PF00249.31 EGG18990.1 - 6.9e-19 67.8 6.5 1e-09 38.4 0.2 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain DnaJ PF00226.31 EGG18990.1 - 1.6e-18 66.6 0.1 6e-18 64.7 0.1 2.1 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-bind_6 PF13921.6 EGG18990.1 - 9e-10 38.7 6.5 1.5e-05 25.1 0.6 3.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain DUF5053 PF16476.5 EGG18990.1 - 0.032 13.9 0.9 0.87 9.3 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) Fcf2 PF08698.11 EGG18991.1 - 7.7e-15 55.1 3.9 9.3e-15 54.8 1.0 2.4 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing DUF4724 PF15852.5 EGG18991.1 - 0.022 15.2 3.3 0.029 14.8 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4724) SLAM PF06214.11 EGG18991.1 - 0.062 13.3 0.6 0.1 12.6 0.6 1.5 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein Alg14 PF08660.11 EGG18991.1 - 0.24 11.3 1.1 1.7 8.6 0.0 2.5 2 1 1 3 3 3 0 Oligosaccharide biosynthesis protein Alg14 like XRN1_D1 PF18332.1 EGG18991.1 - 0.66 9.7 7.2 0.061 13.1 1.1 1.9 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D1 domain FANCI_S2 PF14676.6 EGG18993.1 - 1.9e-31 109.6 0.3 2.2e-30 106.1 0.1 3.1 2 0 0 2 2 2 1 FANCI solenoid 2 FANCI_HD2 PF14680.6 EGG18993.1 - 4.4e-25 88.3 0.1 4.4e-25 88.3 0.1 4.2 3 1 0 3 3 3 1 FANCI helical domain 2 FANCI_S4 PF14678.6 EGG18993.1 - 1.9e-18 66.5 9.6 1.9e-18 66.5 9.6 3.7 3 0 0 3 3 3 1 FANCI solenoid 4 FANCI_S1 PF14675.6 EGG18993.1 - 1.4e-15 57.5 0.2 1.4e-15 57.5 0.2 4.2 4 1 0 4 4 4 1 FANCI solenoid 1 FANCI_HD1 PF14679.6 EGG18993.1 - 1.2e-06 28.4 3.3 0.0001 22.2 0.1 4.0 3 0 0 3 3 3 1 FANCI helical domain 1 CDC45 PF02724.14 EGG18993.1 - 0.0026 16.1 0.9 0.0026 16.1 0.9 4.3 5 0 0 5 5 5 1 CDC45-like protein 23S_rRNA_IVP PF05635.11 EGG18993.1 - 0.035 14.4 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein CdiI_2 PF18593.1 EGG18993.1 - 0.056 14.1 0.3 6.6 7.5 0.0 3.6 4 0 0 4 4 4 0 CdiI immunity protein PA26 PF04636.13 EGG18994.1 - 1.3 7.9 13.5 1.6 7.6 13.3 1.3 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) CCSAP PF15748.5 EGG18994.1 - 2.7 8.1 23.9 0.32 11.2 19.4 1.6 1 1 1 2 2 2 0 Centriole, cilia and spindle-associated Calcipressin PF04847.12 EGG18995.1 - 1.6e-09 37.8 0.1 1.6e-09 37.8 0.1 1.5 2 0 0 2 2 2 1 Calcipressin SNAPc19 PF15497.6 EGG18995.1 - 4.9 7.7 9.0 2.4 8.7 6.2 1.9 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 IQ PF00612.27 EGG18996.1 - 3.9e-10 38.6 2.4 0.00079 19.0 0.3 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Peptidase_C1 PF00112.23 EGG18997.1 - 8.1e-76 254.9 11.5 1.5e-62 211.6 2.1 2.2 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG18997.1 - 1e-11 45.1 5.0 1.8e-11 44.3 5.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGG18997.1 - 0.00092 18.1 4.2 0.28 9.9 1.3 2.1 2 0 0 2 2 2 2 Peptidase C1-like family BUD22 PF09073.10 EGG18999.1 - 0.14 11.5 23.7 0.16 11.2 23.7 1.1 1 0 0 1 1 1 0 BUD22 SOG2 PF10428.9 EGG18999.1 - 2.8 7.0 18.1 3.9 6.6 18.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RhoGAP PF00620.27 EGG19000.1 - 2e-35 121.9 0.7 3.3e-35 121.2 0.7 1.3 1 0 0 1 1 1 1 RhoGAP domain SKG6 PF08693.10 EGG19000.1 - 2.8e-05 23.4 3.4 7.1e-05 22.1 3.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 EGG19000.1 - 0.0031 17.4 2.0 0.023 14.6 0.1 2.6 2 0 0 2 2 2 1 TMEM154 protein family Plant_vir_prot PF01307.17 EGG19000.1 - 0.096 12.9 0.1 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Plant viral movement protein EphA2_TM PF14575.6 EGG19000.1 - 0.16 12.9 0.0 0.55 11.1 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SF3b1 PF08920.10 EGG19001.1 - 7.2e-33 113.6 12.9 1.2e-32 112.8 0.3 3.1 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT PF02985.22 EGG19001.1 - 3e-14 51.9 6.2 0.033 14.4 0.0 9.4 11 0 0 11 11 10 2 HEAT repeat HEAT_2 PF13646.6 EGG19001.1 - 9e-12 45.2 8.4 0.012 15.9 0.0 7.8 4 2 3 8 8 8 3 HEAT repeats Cnd1 PF12717.7 EGG19001.1 - 4.3e-11 43.1 1.3 0.22 11.6 0.0 6.1 5 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGG19001.1 - 1.6e-09 38.1 1.4 0.23 12.0 0.0 7.5 8 1 1 9 9 8 2 HEAT-like repeat DUF3385 PF11865.8 EGG19001.1 - 4.9e-05 23.3 1.3 4.3 7.2 0.1 5.3 3 1 1 5 5 5 2 Domain of unknown function (DUF3385) IFRD PF05004.13 EGG19001.1 - 6.9e-05 22.1 0.1 0.024 13.7 0.1 3.3 3 1 1 4 4 4 1 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 EGG19001.1 - 0.00012 22.6 1.5 7.5 7.2 0.0 5.2 5 0 0 5 5 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGG19001.1 - 0.00024 20.7 0.2 0.73 9.3 0.0 3.6 3 1 0 3 3 3 2 CLASP N terminal NUC173 PF08161.12 EGG19001.1 - 0.0078 15.9 0.4 3.5 7.2 0.0 4.6 3 1 1 4 4 4 1 NUC173 domain Dopey_N PF04118.14 EGG19001.1 - 0.015 14.4 1.2 16 4.5 0.0 4.0 3 1 0 4 4 4 0 Dopey, N-terminal Arm PF00514.23 EGG19001.1 - 0.021 14.9 1.8 26 5.1 0.0 4.7 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 EGG19001.1 - 0.024 14.9 0.0 0.34 11.2 0.0 3.0 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain RTP1_C1 PF10363.9 EGG19001.1 - 0.07 13.3 2.3 2 8.6 0.1 4.0 4 2 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 EGG19001.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central B56 PF01603.20 EGG19001.1 - 0.15 11.0 1.2 1.4 7.8 0.1 2.7 3 0 0 3 3 3 0 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.25 EGG19002.1 - 0.00011 21.7 1.6 0.0003 20.2 1.4 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19002.1 - 0.00025 20.4 0.2 0.00087 18.6 0.1 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase DUF4691 PF15762.5 EGG19002.1 - 0.008 16.4 0.6 0.015 15.5 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4691) Orf78 PF06024.12 EGG19002.1 - 0.053 13.8 1.7 0.079 13.3 0.2 2.0 2 0 0 2 2 2 0 Orf78 (ac78) Formyl_trans_N PF00551.19 EGG19003.1 - 5.2e-47 159.9 0.3 6e-47 159.7 0.3 1.0 1 0 0 1 1 1 1 Formyl transferase Flavoprotein PF02441.19 EGG19003.1 - 0.12 12.1 0.2 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Flavoprotein Flagellin_IN PF07196.13 EGG19003.1 - 0.39 10.9 3.0 4.5 7.6 0.9 2.5 2 0 0 2 2 2 0 Flagellin hook IN motif Mst1_SARAH PF11629.8 EGG19003.1 - 0.53 10.4 2.3 18 5.5 0.0 3.2 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 NDT80_PhoG PF05224.12 EGG19004.1 - 5.3e-21 75.7 0.4 5.3e-21 75.7 0.4 5.7 5 1 0 5 5 5 2 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.6 EGG19004.1 - 1.5e-13 50.9 1.1 3.4e-13 49.7 1.1 1.7 1 0 0 1 1 1 1 Chaperone of endosialidase MRF_C1 PF13887.6 EGG19004.1 - 2.4e-09 36.2 0.1 5.2e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 adh_short PF00106.25 EGG19005.1 - 7.1e-34 117.0 0.2 9.9e-34 116.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG19005.1 - 2.9e-28 99.0 0.2 4e-28 98.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG19005.1 - 2e-05 24.6 0.1 2.9e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGG19005.1 - 0.011 14.8 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CLU PF13236.6 EGG19006.1 - 7.4e-61 205.8 0.0 1.7e-60 204.6 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria LRR_6 PF13516.6 EGG19006.1 - 5.8e-08 32.2 15.4 0.55 10.4 0.0 9.9 10 0 0 10 10 10 2 Leucine Rich repeat eIF3_p135 PF12807.7 EGG19006.1 - 5.7e-07 29.7 4.0 6.6e-07 29.5 0.0 3.0 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 DUF4037 PF13228.6 EGG19006.1 - 0.13 13.1 0.0 0.36 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) SHMT PF00464.19 EGG19007.1 - 3.8e-178 592.1 0.0 6e-178 591.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydroxymethyltransferase RasGEF PF00617.19 EGG19007.1 - 1.1e-56 191.8 3.8 3.4e-56 190.2 0.2 2.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGG19007.1 - 7e-22 77.7 0.8 7e-22 77.7 0.8 2.4 3 0 0 3 3 3 1 RasGEF N-terminal motif DUF4264 PF14084.6 EGG19007.1 - 0.022 14.4 0.1 5.7 6.7 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) Beta_elim_lyase PF01212.21 EGG19007.1 - 0.025 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase LisH_TPL PF17814.1 EGG19007.1 - 5.4 6.8 5.0 0.78 9.4 0.5 2.0 2 0 0 2 2 2 0 LisH-like dimerisation domain VIT PF08487.10 EGG19008.1 - 1.2e-40 138.1 0.1 1.2e-40 138.1 0.1 2.8 3 0 0 3 3 2 1 Vault protein inter-alpha-trypsin domain PARP PF00644.20 EGG19008.1 - 1.7e-28 99.5 0.2 1.1e-27 96.9 0.2 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain 14-3-3 PF00244.20 EGG19008.1 - 4e-26 91.9 5.5 6.7e-26 91.2 2.5 2.5 2 0 0 2 2 2 1 14-3-3 protein VWA_3 PF13768.6 EGG19008.1 - 8.6e-22 77.7 0.0 2.5e-21 76.2 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EGG19008.1 - 3.9e-15 56.5 0.1 4e-14 53.3 0.0 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 EGG19008.1 - 2.8e-13 49.6 0.0 1.4e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 EGG19008.1 - 2.3e-07 31.4 0.0 1.1e-06 29.2 0.0 2.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_60s PF00428.19 EGG19008.1 - 8e-05 23.2 1.7 8e-05 23.2 1.7 6.3 7 0 0 7 7 5 1 60s Acidic ribosomal protein PARP_reg PF02877.14 EGG19008.1 - 0.0023 18.0 0.0 0.0023 18.0 0.0 2.9 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase, regulatory domain BRCT_2 PF16589.5 EGG19008.1 - 0.0088 16.4 2.7 0.0088 16.4 2.7 3.3 3 1 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG19008.1 - 0.025 15.0 0.2 0.12 12.7 0.1 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain FNIP PF05725.12 EGG19010.1 - 4.4e-05 23.6 37.4 0.02 15.0 0.4 8.7 9 1 1 10 10 10 5 FNIP Repeat GMC_oxred_N PF00732.19 EGG19011.1 - 9.3e-30 104.0 0.0 2.1e-29 102.9 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGG19011.1 - 6.7e-21 75.3 0.0 1.1e-20 74.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EGG19011.1 - 0.0032 17.1 0.0 0.027 14.1 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGG19011.1 - 0.027 14.7 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGG19011.1 - 0.088 12.0 0.0 9.1 5.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGG19011.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 EGG19011.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain FNIP PF05725.12 EGG19012.1 - 4e-05 23.7 0.8 4e-05 23.7 0.8 7.2 6 3 4 10 10 10 2 FNIP Repeat DUF5418 PF17439.2 EGG19012.1 - 0.02 15.0 0.5 0.043 13.9 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5418) F-box-like PF12937.7 EGG19012.1 - 0.03 14.2 0.2 0.075 12.9 0.2 1.7 1 0 0 1 1 1 0 F-box-like Stealth_CR2 PF11380.8 EGG19013.1 - 3.2e-40 136.7 0.6 6.5e-40 135.7 0.6 1.5 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 EGG19013.1 - 3.7e-15 55.6 0.1 8.9e-15 54.3 0.1 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 EGG19013.1 - 3.7e-13 48.9 0.0 7.5e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 EGG19013.1 - 2.8e-10 39.9 0.1 9e-10 38.3 0.1 1.9 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Kelch_1 PF01344.25 EGG19014.1 - 8.8e-20 70.0 6.6 1.8e-07 30.6 0.0 5.4 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 EGG19014.1 - 3.4e-18 65.2 13.7 1.5e-09 37.7 0.0 6.3 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.6 EGG19014.1 - 2.9e-16 59.2 15.3 1.2e-07 31.6 0.0 6.2 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EGG19014.1 - 4.2e-13 49.2 8.9 2.4e-08 34.1 0.0 6.9 6 1 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.15 EGG19014.1 - 8.8e-13 47.7 16.2 2.1e-06 27.5 0.1 6.6 7 0 0 7 7 7 3 Kelch motif Kelch_5 PF13854.6 EGG19014.1 - 1.8e-12 46.9 17.4 2.9e-05 23.9 0.0 6.0 7 0 0 7 7 7 3 Kelch motif F-box PF00646.33 EGG19014.1 - 0.011 15.6 1.7 0.028 14.3 1.7 1.7 1 0 0 1 1 1 0 F-box domain Sedlin_N PF04628.13 EGG19014.1 - 0.072 13.2 0.7 0.65 10.1 0.1 2.3 2 0 0 2 2 2 0 Sedlin, N-terminal conserved region Na_Ca_ex PF01699.24 EGG19015.1 - 1.9e-14 53.9 43.0 3e-08 33.8 13.9 3.9 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 EGG19015.1 - 7.5e-11 42.6 11.1 7.5e-11 42.6 11.1 5.1 5 0 0 5 5 5 1 Inner membrane component domain Bacteriocin_IIc PF10439.9 EGG19015.1 - 0.025 14.7 0.5 1.4 9.1 0.0 2.6 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide GST_C_3 PF14497.6 EGG19016.1 - 1.1e-21 76.9 0.3 1.5e-21 76.4 0.3 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGG19016.1 - 2.2e-10 40.7 0.0 5.3e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGG19016.1 - 1.2e-06 28.8 0.0 5.8e-06 26.6 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG19016.1 - 2.9e-06 27.4 0.1 4.3e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG19016.1 - 0.023 14.7 0.0 0.061 13.3 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ctr PF04145.15 EGG19017.1 - 8.3e-27 94.6 2.4 8.3e-27 94.6 2.4 2.3 2 0 0 2 2 2 1 Ctr copper transporter family DUF5009 PF16401.5 EGG19017.1 - 3.8e-05 23.3 4.2 0.00056 19.5 4.2 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5009) DUF1725 PF08333.11 EGG19017.1 - 0.14 11.9 0.5 0.33 10.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Methyltransf_11 PF08241.12 EGG19018.1 - 6e-14 52.5 0.0 2e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG19018.1 - 3.6e-09 37.2 0.0 1e-08 35.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG19018.1 - 5.2e-06 27.1 0.0 1.5e-05 25.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG19018.1 - 0.002 17.5 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGG19018.1 - 0.0036 17.1 0.0 0.0098 15.7 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Aminotran_5 PF00266.19 EGG19019.1 - 5.9e-88 295.3 0.0 7.1e-88 295.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGG19019.1 - 4.2e-10 39.4 0.0 5.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGG19019.1 - 6.1e-08 32.4 0.1 1e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EGG19019.1 - 8.2e-05 21.5 0.0 0.00014 20.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 EGG19019.1 - 0.0039 15.8 0.2 0.0058 15.2 0.2 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PIN_6 PF17146.4 EGG19020.1 - 5.5e-26 90.9 0.4 2.2e-25 88.9 0.4 2.2 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EGG19020.1 - 1.7e-22 79.3 1.9 4.4e-22 78.0 1.9 1.8 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Methyltransf_11 PF08241.12 EGG19020.1 - 5e-13 49.5 0.0 3.3e-12 46.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG19020.1 - 6.9e-11 42.7 0.0 7.6e-10 39.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG19020.1 - 5.5e-06 27.1 1.8 9.6e-06 26.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG19020.1 - 5.2e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG19020.1 - 9.9e-05 22.2 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain zf-ISL3 PF14690.6 EGG19020.1 - 0.085 13.5 0.1 0.28 11.9 0.1 1.9 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PRO8NT PF08082.11 EGG19020.1 - 0.14 12.1 3.5 0.39 10.7 3.5 1.7 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain DUF373 PF04123.13 EGG19021.1 - 0.28 10.6 4.7 0.47 9.8 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Dickkopf_N PF04706.12 EGG19022.1 - 0.0072 16.8 14.6 0.0072 16.8 14.6 7.2 2 2 4 6 6 6 2 Dickkopf N-terminal cysteine-rich region Ras PF00071.22 EGG19023.1 - 5.1e-56 188.7 1.5 6e-56 188.5 1.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG19023.1 - 1.8e-35 121.7 0.6 2.9e-35 121.1 0.6 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG19023.1 - 2e-21 76.2 0.6 2.3e-21 76.0 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG19023.1 - 2e-08 33.9 0.4 2.5e-08 33.6 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGG19023.1 - 9.6e-06 25.1 1.2 4e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGG19023.1 - 4.7e-05 23.0 0.5 0.0025 17.4 0.1 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG19023.1 - 8.9e-05 22.5 0.1 0.00014 21.9 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGG19023.1 - 0.00069 18.9 0.7 0.4 9.8 0.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit TniB PF05621.11 EGG19023.1 - 0.0023 17.4 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein RsgA_GTPase PF03193.16 EGG19023.1 - 0.0042 17.0 0.2 2.6 7.9 0.0 2.6 1 1 2 3 3 3 2 RsgA GTPase AAA PF00004.29 EGG19023.1 - 0.0096 16.3 0.0 0.031 14.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGG19023.1 - 0.01 15.6 0.1 0.022 14.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 EGG19023.1 - 0.021 14.6 0.1 0.085 12.6 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EGG19023.1 - 0.033 14.5 0.2 3 8.1 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 EGG19023.1 - 0.1 13.0 0.0 0.16 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Ribophorin_II PF05817.14 EGG19024.1 - 6.6e-97 325.6 9.7 7.7e-97 325.4 9.7 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Ribosomal_S15 PF00312.22 EGG19025.1 - 2.9e-11 43.4 4.3 1.5e-09 37.9 4.3 2.6 1 1 0 1 1 1 1 Ribosomal protein S15 SOGA PF11365.8 EGG19025.1 - 0.11 13.6 3.0 0.16 13.1 0.4 2.6 2 1 0 2 2 2 0 Protein SOGA FTCD_N PF07837.12 EGG19026.1 - 1.5e-66 223.5 0.0 2.6e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD PF02971.14 EGG19026.1 - 5.9e-58 195.0 0.0 1e-57 194.2 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase domain FTCD_C PF04961.12 EGG19026.1 - 1.7e-47 161.6 0.0 3.2e-47 160.6 0.0 1.5 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase PheRS_DBD2 PF18554.1 EGG19026.1 - 0.065 13.2 1.4 0.28 11.2 0.1 2.5 2 0 0 2 2 2 0 PheRS DNA binding domain 2 BBS2_Mid PF14783.6 EGG19027.1 - 0.0019 18.2 0.0 0.025 14.6 0.0 2.9 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region PPL5 PF18168.1 EGG19027.1 - 0.021 14.1 9.9 0.22 10.8 0.3 2.4 2 0 0 2 2 2 0 Prim-pol family 5 RNase_H2_suC PF08615.11 EGG19027.1 - 0.049 13.8 2.6 2.2 8.4 0.3 2.5 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) VCBS PF13517.6 EGG19027.1 - 0.074 13.6 0.0 0.38 11.4 0.0 2.3 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EIIBC-GUT_N PF03612.14 EGG19027.1 - 0.12 12.1 13.4 0.072 12.8 6.8 2.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus BBS1 PF14779.6 EGG19027.1 - 0.32 10.4 0.0 0.32 10.4 0.0 2.7 2 0 0 2 2 1 0 Ciliary BBSome complex subunit 1 Itfg2 PF15907.5 EGG19027.1 - 0.35 9.9 0.0 0.35 9.9 0.0 3.3 4 0 0 4 4 4 0 Integrin-alpha FG-GAP repeat-containing protein 2 Eapp_C PF10238.9 EGG19027.1 - 0.78 9.8 14.4 1.9 8.6 10.2 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein Tim54 PF11711.8 EGG19027.1 - 0.95 8.2 10.9 0.093 11.5 1.9 2.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Orf78 PF06024.12 EGG19027.1 - 1.1 9.6 8.4 0.91 9.9 2.9 2.9 2 0 0 2 2 2 0 Orf78 (ac78) PRP1_N PF06424.12 EGG19027.1 - 1.4 9.3 13.3 0.2 12.0 4.1 2.7 3 0 0 3 3 2 0 PRP1 splicing factor, N-terminal DUF2228 PF10228.9 EGG19027.1 - 3.9 7.2 11.6 0.37 10.5 0.5 2.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) Acetyltransf_2 PF00797.17 EGG19027.1 - 4.3 7.1 10.0 0.79 9.5 5.0 2.1 2 0 0 2 2 2 0 N-acetyltransferase DUF4746 PF15928.5 EGG19027.1 - 4.7 6.6 11.9 0.44 9.9 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DAG_kinase_N PF14513.6 EGG19027.1 - 7.3 6.8 19.6 0.12 12.5 4.7 3.3 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus AAA_11 PF13086.6 EGG19028.1 - 3.1e-18 66.5 0.3 6.5e-08 32.7 0.1 3.0 2 1 1 3 3 3 2 AAA domain AAA_12 PF13087.6 EGG19028.1 - 1.3e-15 57.6 0.0 1.3e-15 57.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGG19028.1 - 4.9e-11 42.7 0.0 1.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG19028.1 - 7.3e-10 39.3 0.1 9.5e-09 35.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EGG19028.1 - 1.3e-07 31.6 0.1 0.004 16.9 0.0 3.7 3 1 1 4 4 4 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EGG19028.1 - 9.5e-06 25.4 0.0 2.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DEAD PF00270.29 EGG19028.1 - 0.00038 20.3 0.1 0.026 14.3 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_RecD PF05127.14 EGG19028.1 - 0.0012 18.7 0.2 0.0082 16.0 0.0 2.4 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 EGG19028.1 - 0.0032 17.7 0.0 0.012 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EGG19028.1 - 0.012 15.1 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Anillin PF08174.11 EGG19028.1 - 0.033 14.6 1.2 0.14 12.6 1.2 2.1 1 0 0 1 1 1 0 Cell division protein anillin DDE_Tnp_1_6 PF13751.6 EGG19028.1 - 0.13 12.5 0.8 0.32 11.2 0.8 1.6 1 0 0 1 1 1 0 Transposase DDE domain Rieske PF00355.26 EGG19029.1 - 7.3e-14 51.5 0.0 1.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EGG19029.1 - 2.2e-10 40.8 0.4 4.5e-10 39.9 0.4 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rep_fac_C PF08542.11 EGG19030.1 - 1.7e-15 57.2 0.0 3e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EGG19030.1 - 3.9e-14 52.7 0.0 2.2e-12 47.0 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EGG19030.1 - 7.3e-14 52.3 0.0 1.3e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGG19030.1 - 1.8e-06 28.0 0.0 3.3e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EGG19030.1 - 0.00012 22.5 0.2 0.0019 18.6 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EGG19030.1 - 0.00015 21.2 0.0 0.002 17.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EGG19030.1 - 0.00021 21.1 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EGG19030.1 - 0.00022 21.0 0.0 0.00049 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGG19030.1 - 0.00031 20.6 0.0 0.00067 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGG19030.1 - 0.00032 21.0 0.1 0.031 14.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG19030.1 - 0.00054 19.7 0.1 0.0039 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EGG19030.1 - 0.001 19.1 0.0 0.0098 15.9 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG19030.1 - 0.0069 16.2 0.3 0.045 13.5 0.3 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_5 PF07728.14 EGG19030.1 - 0.009 16.0 0.1 0.046 13.7 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EGG19030.1 - 0.011 16.2 0.0 0.018 15.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 EGG19030.1 - 0.015 15.1 0.0 0.062 13.1 0.0 1.9 2 1 1 3 3 3 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 EGG19030.1 - 0.017 15.5 0.4 0.42 10.9 0.4 2.3 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EGG19030.1 - 0.019 14.2 0.2 0.16 11.1 0.2 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EGG19030.1 - 0.02 14.3 0.0 0.88 9.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_assoc_2 PF16193.5 EGG19030.1 - 0.021 15.1 0.0 0.055 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA C-terminal domain DUF815 PF05673.13 EGG19030.1 - 0.021 14.0 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Avl9 PF09794.9 EGG19032.1 - 9.4e-101 337.2 7.7 2.7e-100 335.7 7.7 1.9 1 1 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 EGG19032.1 - 1.2e-07 31.6 1.5 1.2e-07 31.6 1.5 3.6 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2347) DUF3446 PF11928.8 EGG19032.1 - 2 8.8 19.0 1 9.7 2.7 3.6 3 0 0 3 3 3 0 Early growth response N-terminal domain Secretin_N_2 PF07655.13 EGG19032.1 - 9.2 6.9 34.4 5 7.7 5.4 4.7 4 0 0 4 4 4 0 Secretin N-terminal domain Pribosyltran PF00156.27 EGG19033.1 - 4.7e-20 71.7 0.3 5.4e-20 71.5 0.3 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain EB PF01683.18 EGG19034.1 - 0.0078 16.5 9.9 0.0078 16.5 9.9 8.4 2 2 4 6 6 6 3 EB module Dickkopf_N PF04706.12 EGG19034.1 - 0.0097 16.4 16.8 0.021 15.3 5.9 6.5 5 1 1 6 6 6 3 Dickkopf N-terminal cysteine-rich region RIFIN PF02009.16 EGG19035.1 - 0.41 10.5 1.4 0.45 10.4 1.4 1.1 1 0 0 1 1 1 0 Rifin HhH-GPD PF00730.25 EGG19036.1 - 5.3e-18 65.4 0.0 1.7e-17 63.8 0.0 2.0 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 EGG19036.1 - 2.2e-10 40.5 0.0 0.0004 20.3 0.0 2.7 2 0 0 2 2 2 2 NUDIX domain HHH PF00633.23 EGG19036.1 - 2.2e-06 27.2 0.1 6.4e-06 25.8 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 EGG19036.1 - 0.61 10.5 2.5 1 9.8 2.5 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Tir_receptor_C PF07489.11 EGG19036.1 - 2.3 8.1 16.6 0.53 10.2 4.4 3.1 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) C-terminus DUF3316 PF11777.8 EGG19036.1 - 4.5 7.3 10.0 0.29 11.2 1.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3316) Mis12 PF05859.12 EGG19037.1 - 1e-18 67.7 0.7 1e-18 67.7 0.7 2.2 1 1 1 2 2 2 1 Mis12 protein Atg14 PF10186.9 EGG19037.1 - 7.3 5.6 24.6 0.17 11.0 17.9 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PseudoU_synth_2 PF00849.22 EGG19038.1 - 8e-28 97.5 2.1 2.1e-27 96.2 0.0 2.6 3 0 0 3 3 3 1 RNA pseudouridylate synthase Malic_M PF03949.15 EGG19038.1 - 0.1 11.8 0.2 0.19 11.0 0.2 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain ALMT PF11744.8 EGG19038.1 - 1.9 7.2 14.9 0.027 13.3 3.3 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter ASD2 PF08687.11 EGG19038.1 - 6.7 6.2 17.1 0.31 10.6 7.2 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Siva PF05458.12 EGG19040.1 - 0.014 15.1 17.8 0.022 14.4 17.8 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Pox_Ag35 PF03286.14 EGG19040.1 - 3.3 7.5 10.5 0.82 9.4 6.8 1.7 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Ctr PF04145.15 EGG19041.1 - 3.9e-31 108.7 0.5 6.4e-31 108.0 0.5 1.4 1 0 0 1 1 1 1 Ctr copper transporter family DUF2407_C PF13373.6 EGG19041.1 - 0.032 14.4 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF1869 PF08956.10 EGG19041.1 - 0.065 13.2 0.6 0.7 9.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) Gelsolin PF00626.22 EGG19042.1 - 7.7e-35 118.6 0.1 6e-11 42.1 0.1 5.9 5 0 0 5 5 5 5 Gelsolin repeat PBD PF00786.28 EGG19042.1 - 3.2e-19 69.0 3.3 1.3e-08 35.0 0.0 3.4 3 0 0 3 3 3 2 P21-Rho-binding domain PKD_channel PF08016.12 EGG19043.1 - 4.6e-50 170.5 14.9 4.6e-50 170.5 14.9 1.6 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 EGG19043.1 - 1.6e-10 40.6 25.0 1.6e-10 40.6 25.0 2.7 3 0 0 3 3 3 1 Ion transport protein YrbL-PhoP_reg PF10707.9 EGG19043.1 - 0.0083 15.7 1.0 0.024 14.1 0.6 2.0 1 1 1 2 2 2 1 PhoP regulatory network protein YrbL Pex14_N PF04695.13 EGG19043.1 - 0.79 10.4 7.6 0.53 10.9 0.5 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CemA PF03040.14 EGG19043.1 - 1.4 8.8 14.4 1.7 8.5 0.1 3.0 3 0 0 3 3 3 0 CemA family DUF3192 PF11399.8 EGG19043.1 - 5.6 7.0 8.1 4.1 7.4 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3192) DSPc PF00782.20 EGG19044.1 - 4.2e-21 75.2 0.0 5.4e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGG19044.1 - 1.8e-06 28.1 0.0 3.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 EGG19044.1 - 1.9e-05 24.4 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 EGG19044.1 - 0.00027 20.6 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EGG19044.1 - 0.00051 19.7 0.0 0.00078 19.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 EGG19044.1 - 0.00055 20.2 0.1 0.00086 19.6 0.1 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 EGG19044.1 - 0.05 13.6 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Myotub-related PF06602.14 EGG19045.1 - 2.7e-06 26.6 7.7 0.00049 19.1 0.0 4.0 4 0 0 4 4 4 2 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EGG19045.1 - 0.00034 20.7 0.1 0.002 18.2 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family MutL_C PF08676.11 EGG19046.1 - 4.9e-14 52.3 0.0 4.9e-14 52.3 0.0 2.7 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EGG19046.1 - 4.7e-10 39.4 0.7 4.7e-10 39.4 0.7 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGG19046.1 - 0.00013 22.4 0.1 0.00038 20.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIA PF03153.13 EGG19046.1 - 0.0016 18.5 13.2 0.0016 18.5 13.2 4.4 2 1 1 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF719 PF05334.13 EGG19046.1 - 0.013 15.7 5.3 0.013 15.7 5.3 4.9 6 0 0 6 6 6 0 Protein of unknown function (DUF719) MCU PF04678.13 EGG19046.1 - 0.073 13.2 2.4 0.19 11.8 2.4 1.7 1 0 0 1 1 1 0 Mitochondrial calcium uniporter MMR_HSR1 PF01926.23 EGG19047.1 - 2e-08 34.3 4.6 2.1e-08 34.2 1.8 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGG19047.1 - 1.9e-05 24.1 6.8 8.7e-05 21.9 3.8 2.9 2 1 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 EGG19047.1 - 0.00012 22.1 2.5 0.00019 21.4 0.3 2.5 2 0 0 2 2 2 1 RsgA GTPase Golgin_A5 PF09787.9 EGG19047.1 - 0.00081 18.9 1.5 0.00081 18.9 1.5 2.4 2 1 0 2 2 2 1 Golgin subfamily A member 5 Roc PF08477.13 EGG19047.1 - 0.0037 17.5 0.0 0.0037 17.5 0.0 2.7 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EGG19047.1 - 0.036 14.3 0.5 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Spermine_synt_N PF17284.2 EGG19047.1 - 0.039 13.9 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 Spermidine synthase tetramerisation domain ABC_tran PF00005.27 EGG19047.1 - 0.044 14.3 0.1 0.044 14.3 0.1 2.6 2 1 0 2 2 2 0 ABC transporter Ras PF00071.22 EGG19047.1 - 0.05 13.2 0.2 0.05 13.2 0.2 3.1 3 1 0 3 3 3 0 Ras family AAA_18 PF13238.6 EGG19047.1 - 0.075 13.6 1.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain TMCO5 PF14992.6 EGG19047.1 - 0.98 8.9 13.9 3.9 7.0 0.4 2.5 2 1 0 2 2 2 0 TMCO5 family AAA_23 PF13476.6 EGG19047.1 - 4.1 7.8 18.5 0.38 11.2 9.3 2.7 2 2 0 2 2 2 0 AAA domain DUF4164 PF13747.6 EGG19047.1 - 9.8 6.5 7.0 4.3 7.7 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Vault PF01505.18 EGG19048.1 - 3.9e-53 177.3 0.3 1.5e-11 44.3 0.0 4.6 4 0 0 4 4 4 4 Major Vault Protein repeat domain Vault_2 PF17794.1 EGG19048.1 - 1.4e-36 124.7 0.3 8.1e-27 93.4 0.1 3.1 3 0 0 3 3 3 2 Major Vault Protein repeat domain YL1 PF05764.13 EGG19048.1 - 0.0018 18.5 18.9 0.0028 17.8 18.9 1.3 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.12 EGG19048.1 - 0.019 14.4 20.8 0.029 13.8 20.8 1.2 1 0 0 1 1 1 0 SDA1 PCM1_C PF15717.5 EGG19048.1 - 0.025 13.3 15.3 0.035 12.8 15.3 1.2 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Presenilin PF01080.17 EGG19048.1 - 0.046 12.5 15.7 0.063 12.0 15.7 1.2 1 0 0 1 1 1 0 Presenilin CCSAP PF15748.5 EGG19048.1 - 0.076 13.2 13.6 0.12 12.5 13.6 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Pex14_N PF04695.13 EGG19048.1 - 0.17 12.5 15.3 0.32 11.7 15.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4045 PF13254.6 EGG19048.1 - 0.37 10.4 10.6 0.49 10.0 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Lin-8 PF03353.15 EGG19048.1 - 0.42 10.1 22.4 0.54 9.8 22.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Suf PF05843.14 EGG19048.1 - 0.75 9.7 12.2 1.1 9.1 12.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nop14 PF04147.12 EGG19048.1 - 0.78 7.9 29.9 1.1 7.4 29.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGG19048.1 - 0.9 7.8 27.8 1.4 7.1 27.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 EGG19048.1 - 1 8.1 15.1 1.6 7.4 15.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein OATP PF03137.20 EGG19048.1 - 1.1 7.4 2.5 1.7 6.9 2.5 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RR_TM4-6 PF06459.12 EGG19048.1 - 1.3 8.8 20.2 2.4 7.9 20.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.9 EGG19048.1 - 1.8 8.6 9.1 3.4 7.7 9.1 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family Nop53 PF07767.11 EGG19048.1 - 2.9 7.2 29.8 5.2 6.3 29.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FAM163 PF15069.6 EGG19048.1 - 5.8 7.3 5.8 13 6.2 5.8 1.6 1 0 0 1 1 1 0 FAM163 family Neur_chan_memb PF02932.16 EGG19048.1 - 8.2 6.4 9.8 17 5.4 9.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region 2-oxogl_dehyd_N PF16078.5 EGG19049.1 - 0.00015 21.3 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus FMO-like PF00743.19 EGG19050.1 - 3.2e-68 230.5 1.0 6.5e-68 229.4 1.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGG19050.1 - 2.2e-11 43.6 0.1 2e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGG19050.1 - 2.3e-08 33.6 0.1 4.5e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGG19050.1 - 1.5e-05 24.4 0.0 0.00066 19.0 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 EGG19050.1 - 0.00036 21.0 1.9 0.22 12.1 0.0 4.0 3 2 2 5 5 5 1 Ankyrin repeats (3 copies) DUF2140 PF09911.9 EGG19050.1 - 0.49 9.9 6.5 0.39 10.2 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) Ank_2 PF12796.7 EGG19051.1 - 3.5e-08 33.9 1.5 0.021 15.4 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19051.1 - 5.8e-07 29.9 0.0 1.4 9.6 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19051.1 - 0.013 15.8 0.0 12 6.4 0.0 4.5 5 0 0 5 5 5 0 Ankyrin repeats (many copies) SR-25 PF10500.9 EGG19051.1 - 0.057 13.0 3.5 0.094 12.3 3.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1117 PF06547.12 EGG19051.1 - 0.24 12.0 1.2 0.53 10.9 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1117) His_kinase PF06580.13 EGG19051.1 - 0.31 11.4 5.2 15 6.0 0.0 3.8 3 0 0 3 3 3 0 Histidine kinase DUF3447 PF11929.8 EGG19052.1 - 0.0003 20.7 0.8 0.0003 20.7 0.8 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EGG19052.1 - 0.007 16.9 0.0 0.025 15.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DUF4116 PF13475.6 EGG19052.1 - 0.078 12.7 0.4 23 4.8 0.1 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Podoplanin PF05808.11 EGG19053.1 - 0.0022 18.1 0.9 0.01 15.9 0.0 2.3 2 0 0 2 2 2 1 Podoplanin Glycophorin_A PF01102.18 EGG19053.1 - 0.007 16.6 0.0 0.031 14.5 0.0 2.2 1 0 0 1 1 1 1 Glycophorin A Adeno_E3_CR2 PF02439.15 EGG19053.1 - 0.0097 15.6 6.7 0.026 14.3 6.7 1.7 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Syndecan PF01034.20 EGG19053.1 - 0.032 14.2 5.5 0.11 12.4 4.8 2.1 2 0 0 2 2 2 0 Syndecan domain CBM49 PF09478.10 EGG19053.1 - 0.036 14.4 0.3 0.036 14.4 0.3 2.5 3 0 0 3 3 3 0 Carbohydrate binding domain CBM49 Chordopox_A13L PF05961.11 EGG19053.1 - 0.038 14.2 3.6 0.086 13.1 3.6 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein SKG6 PF08693.10 EGG19053.1 - 0.06 12.8 6.8 0.14 11.6 6.8 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 EGG19053.1 - 0.19 12.6 0.9 0.45 11.4 0.9 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gram_pos_anchor PF00746.21 EGG19053.1 - 0.74 9.8 2.3 1.3 9.1 0.1 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif FeoB_associated PF12669.7 EGG19053.1 - 0.91 10.0 5.2 2.9 8.4 5.2 1.9 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein TNFR_16_TM PF18422.1 EGG19053.1 - 1.1 9.3 5.6 3.7 7.6 5.6 1.9 1 1 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF4064 PF13273.6 EGG19054.1 - 0.00047 20.4 1.5 0.0048 17.2 0.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF4064) STN PF07660.14 EGG19054.1 - 1.3 8.8 5.5 4.5 7.2 0.5 2.7 3 0 0 3 3 3 0 Secretin and TonB N terminus short domain Claudin_3 PF06653.11 EGG19054.1 - 1.3 8.9 7.5 1.6 8.7 4.1 2.4 1 1 1 2 2 2 0 Tight junction protein, Claudin-like SHP PF03579.13 EGG19054.1 - 3.2 7.8 8.9 0.16 11.9 0.7 2.3 1 1 1 2 2 2 0 Small hydrophobic protein CENP-B_dimeris PF09026.10 EGG19055.1 - 0.00027 21.3 10.0 0.00027 21.3 10.0 2.4 3 0 0 3 3 3 1 Centromere protein B dimerisation domain RXT2_N PF08595.11 EGG19055.1 - 0.0094 16.0 2.2 0.0094 16.0 2.2 2.3 2 0 0 2 2 2 1 RXT2-like, N-terminal DcuC PF03606.15 EGG19055.1 - 0.067 11.6 0.0 0.095 11.1 0.0 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier FAE1_CUT1_RppA PF08392.12 EGG19055.1 - 0.078 12.3 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein CCDC142 PF14923.6 EGG19055.1 - 0.14 10.9 0.2 0.23 10.2 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil protein 142 EIIBC-GUT_N PF03612.14 EGG19055.1 - 0.42 10.3 3.1 0.24 11.1 0.4 1.9 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus FAM176 PF14851.6 EGG19055.1 - 0.63 9.7 8.8 0.031 13.9 2.5 2.0 2 1 1 3 3 3 0 FAM176 family Dynein_AAA_lid PF17852.1 EGG19055.1 - 0.81 9.8 2.8 15 5.7 0.1 2.8 3 0 0 3 3 3 0 Dynein heavy chain AAA lid domain MRNIP PF15749.5 EGG19055.1 - 1.2 9.9 6.8 0.33 11.7 1.5 2.3 2 0 0 2 2 2 0 MRN-interacting protein DUF2457 PF10446.9 EGG19055.1 - 2.4 7.2 14.1 4.5 6.3 14.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AIM3 PF17096.5 EGG19055.1 - 2.9 8.9 5.5 11 7.0 5.5 2.0 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 NOA36 PF06524.12 EGG19055.1 - 3.9 6.7 18.7 0.098 12.0 12.2 1.5 2 0 0 2 2 2 0 NOA36 protein CD20 PF04103.15 EGG19057.1 - 0.015 15.4 2.1 0.015 15.4 2.1 2.4 1 1 1 2 2 2 0 CD20-like family DUF3784 PF12650.7 EGG19057.1 - 0.032 14.4 0.2 0.032 14.4 0.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) DUF1218 PF06749.12 EGG19057.1 - 0.14 12.7 0.4 0.14 12.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Cation_ATPase_C PF00689.21 EGG19057.1 - 0.19 11.4 3.9 0.33 10.6 3.9 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Claudin_3 PF06653.11 EGG19057.1 - 0.52 10.2 9.1 0.091 12.7 5.5 1.5 2 0 0 2 2 2 0 Tight junction protein, Claudin-like FPN1 PF06963.12 EGG19058.1 - 2.5e-62 210.9 5.7 5.5e-31 107.6 0.2 2.1 2 0 0 2 2 2 2 Ferroportin1 (FPN1) MFS_1 PF07690.16 EGG19058.1 - 1.4e-10 40.7 6.0 8.2e-10 38.1 2.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily ISK_Channel PF02060.15 EGG19058.1 - 0.014 15.1 0.1 0.046 13.4 0.1 1.9 1 0 0 1 1 1 0 Slow voltage-gated potassium channel FAM76 PF16046.5 EGG19058.1 - 9.4 5.5 6.4 0.48 9.7 0.1 1.8 2 0 0 2 2 2 0 FAM76 protein FNIP PF05725.12 EGG19061.1 - 2.1e-06 27.8 44.9 0.067 13.4 0.2 11.8 11 3 3 14 14 14 6 FNIP Repeat Plectin PF00681.20 EGG19061.1 - 0.027 14.3 0.0 6.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Plectin repeat LRR_4 PF12799.7 EGG19061.1 - 0.097 13.1 48.3 2.4 8.7 2.7 13.7 11 5 3 14 14 14 0 Leucine Rich repeats (2 copies) F-box PF00646.33 EGG19061.1 - 2.1 8.4 6.3 2.1 8.3 3.3 2.8 2 0 0 2 2 2 0 F-box domain FNIP PF05725.12 EGG19062.1 - 0.46 10.7 19.5 1.4 9.2 0.1 6.1 6 1 0 6 6 6 0 FNIP Repeat SUIM_assoc PF16619.5 EGG19062.1 - 6.8 6.8 13.8 13 6.0 1.2 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FNIP PF05725.12 EGG19063.1 - 0.0051 17.0 25.7 17 5.7 0.7 9.0 7 2 1 8 8 8 4 FNIP Repeat LRR_4 PF12799.7 EGG19063.1 - 0.14 12.6 0.1 0.14 12.6 0.1 8.1 7 3 3 10 10 10 0 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 EGG19063.1 - 0.84 10.4 4.5 1.9 9.3 0.2 3.5 2 0 0 2 2 2 0 Leucine Rich Repeat FNIP PF05725.12 EGG19064.1 - 6.2e-06 26.3 0.5 0.23 11.7 1.1 5.1 4 1 0 4 4 4 2 FNIP Repeat LRR_4 PF12799.7 EGG19064.1 - 0.14 12.6 27.0 0.64 10.5 0.8 7.2 6 2 2 8 8 8 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG19064.1 - 1.4 8.7 20.0 0.86 9.4 0.6 5.4 4 1 0 5 5 5 0 Leucine rich repeat FNIP PF05725.12 EGG19065.1 - 2.2e-07 30.9 13.1 0.084 13.0 0.1 6.3 5 2 2 7 7 7 4 FNIP Repeat LRR_8 PF13855.6 EGG19065.1 - 0.00019 21.1 11.0 1.5 8.7 0.8 6.2 5 1 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.33 EGG19065.1 - 1.9 9.3 12.0 22 6.1 0.5 6.0 4 1 0 4 4 4 0 Leucine Rich Repeat FKBP_N_2 PF18023.1 EGG19066.1 - 0.044 13.9 0.8 0.14 12.3 0.8 1.8 1 0 0 1 1 1 0 BDBT FKBP like N-terminal AIG2_2 PF13772.6 EGG19066.1 - 0.11 12.9 0.0 0.44 11.0 0.0 2.1 1 0 0 1 1 1 0 AIG2-like family DUF643 PF04867.12 EGG19066.1 - 0.29 11.8 8.9 1.2 9.8 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF643) CM_2 PF01817.21 EGG19067.1 - 0.05 14.0 0.1 2 8.9 0.0 2.2 2 0 0 2 2 2 0 Chorismate mutase type II Ribosomal_S9 PF00380.19 EGG19068.1 - 1.3e-31 109.7 0.3 1.7e-31 109.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HEAT PF02985.22 EGG19070.1 - 9.3e-06 25.5 2.9 0.34 11.3 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 EGG19070.1 - 2.4e-05 24.4 4.9 0.0007 19.7 0.1 4.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGG19070.1 - 4.8e-05 23.9 3.9 0.00014 22.4 0.1 3.9 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EGG19070.1 - 0.00078 19.8 0.0 18 5.8 0.0 5.1 6 0 0 6 6 6 1 HEAT repeats Tti2 PF10521.9 EGG19070.1 - 0.00083 19.0 2.4 0.0011 18.5 0.2 2.3 2 0 0 2 2 2 1 Tti2 family UNC45-central PF11701.8 EGG19070.1 - 0.00093 19.2 0.4 0.015 15.2 0.1 3.2 2 2 1 3 3 3 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 EGG19070.1 - 0.0019 17.8 0.5 0.039 13.5 0.1 3.2 3 1 0 3 3 3 1 CLASP N terminal UPF0149 PF03695.13 EGG19070.1 - 0.082 13.2 0.1 0.37 11.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) Secretin_N_2 PF07655.13 EGG19070.1 - 0.37 11.4 5.7 1.1 9.8 4.1 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain HEAT_2 PF13646.6 EGG19072.1 - 8.3e-06 26.1 0.0 1.7 9.1 0.0 4.5 3 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EGG19072.1 - 9.9e-06 25.4 7.2 0.16 12.3 0.0 5.4 6 0 0 6 6 6 2 HEAT repeat Vac14_Fab1_bd PF12755.7 EGG19072.1 - 3.4e-05 24.4 6.9 0.0003 21.3 0.1 4.6 5 1 1 6 6 5 1 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 EGG19072.1 - 0.00029 20.5 6.5 0.019 14.5 0.2 4.2 3 2 0 4 4 4 2 Tti2 family Cnd1 PF12717.7 EGG19072.1 - 0.0012 18.9 5.6 0.004 17.2 1.0 3.9 3 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EGG19072.1 - 0.0034 17.6 0.2 0.55 10.4 0.0 4.0 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGG19072.1 - 0.0037 17.7 0.1 5.4 7.6 0.0 3.8 2 1 1 3 3 3 1 HEAT-like repeat IFRD PF05004.13 EGG19072.1 - 0.017 14.3 0.8 0.35 9.9 0.0 2.9 2 2 1 3 3 3 0 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.8 EGG19072.1 - 0.027 14.4 7.6 0.22 11.4 0.0 4.8 4 2 1 5 5 5 0 Domain of unknown function (DUF3385) RIH_assoc PF08454.11 EGG19072.1 - 0.066 13.1 6.6 0.22 11.4 0.0 4.2 3 2 0 3 3 3 0 RyR and IP3R Homology associated DUF1981 PF09324.10 EGG19072.1 - 0.081 12.8 1.2 2.4 8.1 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) YiiD_C PF09500.10 EGG19074.1 - 0.0054 16.6 0.1 0.036 13.9 0.0 2.2 2 0 0 2 2 2 1 Putative thioesterase (yiiD_Cterm) FAM167 PF11652.8 EGG19075.1 - 0.14 12.7 0.0 0.36 11.4 0.0 1.7 1 0 0 1 1 1 0 FAM167 Patatin PF01734.22 EGG19076.1 - 6.8e-22 78.7 4.9 9.4e-21 74.9 0.0 3.2 4 0 0 4 4 3 1 Patatin-like phospholipase AAA_22 PF13401.6 EGG19076.1 - 3.3e-08 33.9 0.3 0.0057 16.9 0.0 3.5 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EGG19076.1 - 6.7e-07 29.4 3.6 0.00075 19.6 0.5 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGG19076.1 - 4.4e-06 27.2 0.0 0.019 15.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 EGG19076.1 - 0.00016 21.2 0.1 0.23 10.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 EGG19076.1 - 0.00017 21.9 0.1 0.17 12.3 0.1 3.2 2 0 0 2 2 2 1 RNA helicase Roc PF08477.13 EGG19076.1 - 0.00021 21.5 0.1 0.012 15.8 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EGG19076.1 - 0.00097 18.4 0.0 1.7 7.7 0.0 2.8 2 0 0 2 2 2 2 NB-ARC domain RsgA_GTPase PF03193.16 EGG19076.1 - 0.0034 17.3 11.3 0.0083 16.0 0.0 4.0 5 1 0 5 5 3 2 RsgA GTPase Prok-RING_4 PF14447.6 EGG19076.1 - 0.0054 16.6 7.1 0.0054 16.6 7.1 2.8 3 0 0 3 3 1 1 Prokaryotic RING finger family 4 DUF2344 PF10105.9 EGG19076.1 - 0.0094 15.8 2.7 0.045 13.6 0.1 2.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2344) AAA_33 PF13671.6 EGG19076.1 - 0.014 15.6 0.6 4.7 7.4 0.3 3.1 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EGG19076.1 - 0.017 15.6 0.2 4.4 7.7 0.0 3.3 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EGG19076.1 - 0.018 14.5 0.0 0.63 9.4 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 EGG19076.1 - 0.018 14.8 0.1 7.7 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGG19076.1 - 0.02 15.4 0.0 0.02 15.4 0.0 3.9 4 1 0 4 4 2 0 ABC transporter NACHT PF05729.12 EGG19076.1 - 0.038 13.9 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.6 EGG19076.1 - 0.04 14.0 0.0 0.49 10.5 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EGG19076.1 - 0.1 12.5 11.1 2.6 7.9 0.0 4.2 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea TsaE PF02367.17 EGG19076.1 - 0.11 12.5 0.0 7.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NIBRIN_BRCT_II PF16508.5 EGG19076.1 - 0.12 12.7 1.4 4.2 7.7 0.0 3.4 3 0 0 3 3 3 0 Second BRCT domain on Nijmegen syndrome breakage protein ArsR PF09824.9 EGG19076.1 - 0.15 11.7 4.0 4.7 6.8 0.3 2.8 2 0 0 2 2 2 0 ArsR transcriptional regulator AAA_18 PF13238.6 EGG19076.1 - 0.87 10.1 17.2 2.8 8.5 0.0 4.4 3 1 0 3 3 3 0 AAA domain Neur_chan_memb PF02932.16 EGG19076.1 - 4.5 7.2 9.6 29 4.6 0.0 2.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-C2H2 PF00096.26 EGG19076.1 - 6.1 7.5 6.1 3.7 8.2 0.8 3.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type ELMO_CED12 PF04727.13 EGG19077.1 - 9.3e-11 42.1 11.7 1e-08 35.5 0.4 3.5 1 1 2 3 3 3 2 ELMO/CED-12 family Orthopox_A43R PF06517.11 EGG19077.1 - 0.22 11.3 5.5 0.87 9.4 2.0 2.4 2 0 0 2 2 2 0 Orthopoxvirus A43R protein Ank_2 PF12796.7 EGG19079.1 - 2e-05 25.1 0.0 0.00014 22.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG19079.1 - 7e-05 22.9 0.0 0.16 12.6 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EGG19079.1 - 0.0001 22.8 0.0 1.1 9.9 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EGG19079.1 - 0.037 14.0 0.0 0.19 11.7 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3447) ILEI PF15711.5 EGG19080.1 - 1.2e-44 150.7 2.7 6.2e-14 52.2 0.2 3.4 3 0 0 3 3 3 3 Interleukin-like EMT inducer AAA_lid_11 PF18198.1 EGG19081.1 - 4.3e-19 68.9 0.0 9.7e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 EGG19081.1 - 6.7e-18 65.0 9.9 1.2e-10 41.2 1.2 4.2 4 1 1 5 5 5 3 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 EGG19081.1 - 4.9e-07 29.9 0.1 2e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain DUF2408 PF10303.9 EGG19081.1 - 4.8 7.8 10.3 0.33 11.5 1.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2408) MMR_HSR1 PF01926.23 EGG19082.1 - 7.6e-11 42.1 0.0 0.00015 21.8 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 EGG19082.1 - 1.4e-06 28.5 0.0 0.011 15.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EGG19082.1 - 5.1e-06 27.1 0.8 0.029 14.9 0.0 3.2 3 0 0 3 3 2 2 ABC transporter AAA_29 PF13555.6 EGG19082.1 - 0.00022 20.9 0.1 0.073 12.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG19082.1 - 0.00032 21.1 0.0 0.36 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGG19082.1 - 0.00034 20.5 0.1 0.14 12.1 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 EGG19082.1 - 0.00083 18.6 0.0 0.56 9.4 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.6 EGG19082.1 - 0.0016 18.7 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EGG19082.1 - 0.0049 17.1 0.0 4.5 7.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGG19082.1 - 0.0078 16.8 2.3 6.8 7.3 0.1 4.2 4 0 0 4 4 4 1 AAA domain AAA_21 PF13304.6 EGG19082.1 - 0.0088 15.9 0.2 1.4 8.6 0.1 3.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 EGG19082.1 - 0.026 14.2 0.0 8.2 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGG19082.1 - 0.029 14.8 0.1 1.4 9.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGG19082.1 - 0.044 14.2 0.0 5.5 7.4 0.0 3.2 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 EGG19082.1 - 0.067 13.2 0.0 4 7.5 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 EGG19082.1 - 0.14 11.9 1.2 11 5.7 0.2 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EGG19082.1 - 0.16 12.0 3.9 0.69 9.9 0.0 3.5 3 0 0 3 3 3 0 Dynamin family AAA_7 PF12775.7 EGG19082.1 - 0.18 11.3 2.6 13 5.2 0.0 3.1 3 0 0 3 3 3 0 P-loop containing dynein motor region SWIRM-assoc_2 PF16496.5 EGG19082.1 - 0.88 8.4 14.0 1.7 7.5 14.0 1.5 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Prok-RING_4 PF14447.6 EGG19082.1 - 3.6 7.5 12.6 3 7.8 10.1 2.3 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 BUD22 PF09073.10 EGG19082.1 - 10 5.4 20.4 19 4.5 20.4 1.3 1 0 0 1 1 1 0 BUD22 UPRTase PF14681.6 EGG19083.1 - 1.6e-67 227.0 0.0 2.5e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 EGG19083.1 - 3.4e-55 186.9 0.1 4.9e-55 186.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGG19083.1 - 6.9e-06 26.6 0.0 1.7e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG19083.1 - 0.0021 18.2 0.0 0.0047 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EGG19083.1 - 0.011 15.5 0.1 0.86 9.3 0.0 2.3 1 1 1 2 2 2 0 Cytidylate kinase Pribosyltran PF00156.27 EGG19083.1 - 0.024 14.2 0.0 0.086 12.3 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosyl transferase domain Zeta_toxin PF06414.12 EGG19083.1 - 0.04 13.2 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 EGG19083.1 - 0.043 14.2 0.2 8.2 6.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain CoaE PF01121.20 EGG19083.1 - 0.083 12.6 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Dephospho-CoA kinase CPT PF07931.12 EGG19083.1 - 0.18 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Kin17_mid PF10357.9 EGG19084.1 - 2.3e-44 150.4 1.8 2.3e-44 150.4 1.8 2.8 2 1 1 3 3 2 1 Domain of Kin17 curved DNA-binding protein CBM_20 PF00686.19 EGG19084.1 - 5.8e-19 67.8 0.2 2.3e-18 65.9 0.0 2.1 2 0 0 2 2 1 1 Starch binding domain KN17_SH3 PF18131.1 EGG19084.1 - 1.6e-11 44.1 2.6 3.3e-11 43.1 2.6 1.6 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain zf-C3HC4_2 PF13923.6 EGG19084.1 - 5e-10 39.1 2.6 5e-10 39.1 2.6 2.4 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG19084.1 - 8.4e-09 35.3 5.2 8.4e-09 35.3 5.2 2.5 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG19084.1 - 1.8e-08 34.1 2.0 1.8e-08 34.1 2.0 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 EGG19084.1 - 1.6e-07 31.4 0.1 5.2e-07 29.7 0.1 1.9 1 0 0 1 1 1 1 U-box domain zf-RING_2 PF13639.6 EGG19084.1 - 3.3e-07 30.5 2.8 3.3e-07 30.5 2.8 3.0 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 EGG19084.1 - 2e-06 28.0 2.1 2e-06 28.0 2.1 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EGG19084.1 - 4.8e-06 26.3 1.6 4.8e-06 26.3 1.6 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG19084.1 - 8.3e-06 25.7 2.1 8.3e-06 25.7 2.1 3.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGG19084.1 - 0.00015 21.8 2.7 0.00015 21.8 2.7 2.3 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EGG19084.1 - 0.00034 20.4 2.6 0.00094 19.0 1.2 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 EGG19084.1 - 0.00047 19.9 2.7 0.00047 19.9 2.7 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 KOW PF00467.29 EGG19084.1 - 0.001 19.0 0.3 0.0084 16.0 0.0 2.4 2 0 0 2 2 2 1 KOW motif zf-met PF12874.7 EGG19084.1 - 0.0017 18.7 5.8 0.0047 17.3 5.8 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGG19084.1 - 0.0075 16.5 5.9 0.0075 16.5 5.9 2.0 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding GPI PF06560.11 EGG19084.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) PMSI1 PF15322.6 EGG19084.1 - 3 7.2 8.6 7.3 5.9 8.6 1.6 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative RhoGAP PF00620.27 EGG19085.1 - 1.5e-33 115.8 0.0 3.2e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Borrelia_P83 PF05262.11 EGG19085.1 - 0.029 12.9 10.1 0.043 12.3 10.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 EGG19085.1 - 0.037 13.4 1.7 1.9 7.8 3.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 EGG19085.1 - 0.059 13.2 12.1 0.098 12.5 12.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPL5 PF18168.1 EGG19085.1 - 0.071 12.4 6.1 0.13 11.5 6.1 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Rtf2 PF04641.12 EGG19085.1 - 0.13 11.6 15.9 0.22 10.8 15.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Eapp_C PF10238.9 EGG19085.1 - 0.32 11.0 4.9 0.66 10.0 4.9 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein CASP_C PF08172.12 EGG19085.1 - 0.35 10.2 11.2 0.67 9.2 10.1 1.9 2 0 0 2 2 2 0 CASP C terminal TFIIF_alpha PF05793.12 EGG19085.1 - 0.38 9.3 23.7 0.81 8.2 23.7 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SpoIIP PF07454.11 EGG19085.1 - 0.46 9.9 9.8 0.77 9.2 9.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 EGG19085.1 - 0.58 8.9 11.0 1.2 7.9 11.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RPN2_C PF18004.1 EGG19085.1 - 0.78 9.6 18.2 1.3 8.9 18.2 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CAF-1_p150 PF11600.8 EGG19085.1 - 0.93 9.2 34.7 1.5 8.5 34.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Vfa1 PF08432.10 EGG19085.1 - 1 9.7 19.7 2 8.7 19.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 EIIBC-GUT_N PF03612.14 EGG19085.1 - 2 8.1 5.6 3.4 7.4 5.6 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Zip PF02535.22 EGG19085.1 - 2.1 7.5 4.4 3.2 6.9 4.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NARP1 PF12569.8 EGG19085.1 - 2.2 7.1 19.1 3.2 6.6 19.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Afi1 PF07792.12 EGG19085.1 - 2.9 8.4 9.4 7.3 7.1 9.4 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TAF4 PF05236.14 EGG19085.1 - 3.1 7.5 19.4 8.1 6.1 19.4 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF755 PF05501.11 EGG19085.1 - 3.8 7.8 22.5 1.8 8.8 18.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) MCM_bind PF09739.9 EGG19085.1 - 9.5 4.5 11.7 15 3.9 11.7 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor ETRAMP PF09716.10 EGG19087.1 - 0.58 10.3 4.4 0.4 10.8 0.3 2.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) T2SSC PF11356.8 EGG19087.1 - 6.1 6.7 7.0 6.8 6.6 4.4 2.2 2 1 0 2 2 2 0 Type II secretion system protein C Tim54 PF11711.8 EGG19088.1 - 0.073 11.8 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PDDEXK_6 PF04720.12 EGG19088.1 - 0.16 11.9 1.0 0.24 11.3 1.0 1.3 1 0 0 1 1 1 0 PDDEXK-like family of unknown function BCS1_N PF08740.11 EGG19088.1 - 0.29 11.1 1.7 0.55 10.2 1.7 1.6 1 1 0 1 1 1 0 BCS1 N terminal DUF3245 PF11595.8 EGG19088.1 - 1.9 8.9 7.6 3.1 8.2 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Orf78 PF06024.12 EGG19088.1 - 2.4 8.5 8.6 1.2 9.4 6.4 1.6 2 0 0 2 2 2 0 Orf78 (ac78) DUF2076 PF09849.9 EGG19088.1 - 7.3 6.5 11.1 8.7 6.3 11.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Secretin_N_2 PF07655.13 EGG19090.1 - 0.0018 18.7 2.8 0.0025 18.3 2.8 1.3 1 0 0 1 1 1 1 Secretin N-terminal domain Corazonin PF17308.2 EGG19090.1 - 0.034 14.5 5.3 0.047 14.1 5.3 1.2 1 0 0 1 1 1 0 Pro-corazonin SelK_SelG PF10961.8 EGG19090.1 - 0.087 13.4 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Apis_Csd PF11671.8 EGG19090.1 - 0.1 12.6 5.8 0.13 12.2 5.8 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein Abhydrolase_6 PF12697.7 EGG19091.1 - 3.1e-07 31.2 0.0 4.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG19091.1 - 1.2e-05 25.1 0.5 2.4e-05 24.1 0.5 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF5640 PF18692.1 EGG19091.1 - 0.074 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5640) Ank_2 PF12796.7 EGG19092.1 - 0.00034 21.2 0.1 1.4 9.6 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19092.1 - 0.084 13.5 0.0 5.7 7.6 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) HA2 PF04408.23 EGG19093.1 - 8e-29 100.1 0.0 8e-29 100.1 0.0 4.6 5 0 0 5 5 5 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGG19093.1 - 2.2e-16 60.0 0.1 1.1e-15 57.7 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGG19093.1 - 7e-12 45.7 3.4 1.3e-10 41.5 0.0 3.7 4 0 0 4 4 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG19093.1 - 3.3e-06 27.0 0.7 1.5e-05 24.8 0.7 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGG19093.1 - 0.00038 20.7 3.2 0.00083 19.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 EGG19093.1 - 0.0033 16.8 2.2 0.76 9.1 0.0 3.3 4 0 0 4 4 4 2 FtsK/SpoIIIE family PhoH PF02562.16 EGG19093.1 - 0.0084 15.6 0.7 0.36 10.2 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.6 EGG19093.1 - 0.026 14.9 3.8 0.049 14.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EGG19093.1 - 0.034 13.9 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Clr2 PF10383.9 EGG19093.1 - 0.11 13.2 4.2 9.2 7.0 2.9 3.2 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 DUF3439 PF11921.8 EGG19093.1 - 0.78 9.7 4.1 1.9 8.5 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) ABC_tran PF00005.27 EGG19093.1 - 1.7 9.2 0.0 1.7 9.2 0.0 5.3 5 2 0 5 5 4 0 ABC transporter Dimer_Tnp_hAT PF05699.14 EGG19095.1 - 8.4e-06 25.5 0.3 2.3e-05 24.1 0.3 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Isochorismatase PF00857.20 EGG19096.1 - 3.5e-34 118.5 0.1 4.2e-34 118.2 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family ATG27 PF09451.10 EGG19097.1 - 0.14 12.0 11.4 0.094 12.6 4.1 2.6 3 0 0 3 3 3 0 Autophagy-related protein 27 FAM176 PF14851.6 EGG19098.1 - 0.045 13.4 6.3 0.7 9.5 2.3 2.2 2 0 0 2 2 2 0 FAM176 family Amino_oxidase PF01593.24 EGG19098.1 - 0.11 11.7 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase POX PF07526.11 EGG19098.1 - 0.22 12.1 6.9 0.38 11.3 5.7 1.8 2 0 0 2 2 2 0 Associated with HOX DUF4611 PF15387.6 EGG19098.1 - 0.23 11.7 8.7 7 6.9 4.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF719 PF05334.13 EGG19098.1 - 0.4 10.9 5.3 1.9 8.7 3.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF4834 PF16118.5 EGG19098.1 - 0.53 11.3 9.0 0.43 11.6 5.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Tim54 PF11711.8 EGG19098.1 - 0.66 8.7 8.4 0.96 8.2 4.7 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CSG2 PF16965.5 EGG19098.1 - 0.74 8.7 5.4 1.1 8.1 5.4 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator CobT PF06213.12 EGG19098.1 - 0.79 9.1 6.8 2 7.8 1.3 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT O-antigen_lig PF13425.6 EGG19098.1 - 1.1 8.0 6.4 1.1 8.0 6.4 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein AIF_C PF14721.6 EGG19098.1 - 1.3 9.4 7.9 0.12 12.7 2.8 1.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MRNIP PF15749.5 EGG19098.1 - 2 9.1 15.6 11 6.8 12.0 2.4 2 0 0 2 2 2 0 MRN-interacting protein Ureide_permease PF07168.11 EGG19098.1 - 2.5 6.7 6.1 3.9 6.1 6.1 1.3 1 0 0 1 1 1 0 Ureide permease FAM150 PF15129.6 EGG19098.1 - 3 8.0 6.7 6.9 6.8 4.3 2.2 2 0 0 2 2 2 0 FAM150 family CLN3 PF02487.17 EGG19098.1 - 3.9 6.4 4.8 6.2 5.8 4.8 1.3 1 0 0 1 1 1 0 CLN3 protein Connexin PF00029.19 EGG19098.1 - 5 6.8 6.0 2.1 8.0 3.3 1.6 2 0 0 2 2 2 0 Connexin RP-C_C PF11800.8 EGG19098.1 - 5.1 7.1 9.2 4.1 7.4 6.9 1.8 2 0 0 2 2 2 0 Replication protein C C-terminal region TFB6 PF17110.5 EGG19098.1 - 7.1 6.3 10.3 11 5.7 6.2 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Otopetrin PF03189.13 EGG19098.1 - 8.1 5.1 8.4 11 4.6 8.4 1.2 1 0 0 1 1 1 0 Otopetrin CAC1F_C PF16885.5 EGG19098.1 - 8.9 5.9 9.4 11 5.5 9.4 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term EIIBC-GUT_N PF03612.14 EGG19098.1 - 9.9 5.9 8.8 2.4 7.9 5.3 1.7 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus EGF_2 PF07974.13 EGG19100.1 - 6 7.3 45.3 0.061 13.7 12.2 4.5 4 0 0 4 4 4 0 EGF-like domain tRNA_bind PF01588.20 EGG19101.1 - 1.2e-29 102.3 0.2 3.2e-29 100.9 0.3 1.7 2 0 0 2 2 2 1 Putative tRNA binding domain DUF2431 PF10354.9 EGG19103.1 - 1.1e-17 64.8 0.0 1.1e-17 64.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) DUF2431 PF10354.9 EGG19104.1 - 1.4e-24 87.3 0.1 3.1e-24 86.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Glyco_hydro_9 PF00759.19 EGG19104.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 ketoacyl-synt PF00109.26 EGG19105.1 - 3.4e-63 213.6 0.1 5.9e-63 212.8 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG19105.1 - 7.8e-35 120.9 0.0 6.2e-27 94.9 0.0 2.4 1 1 1 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGG19105.1 - 6.6e-33 113.2 0.1 2.8e-32 111.2 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGG19105.1 - 2.9e-22 79.5 0.0 8e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGG19105.1 - 4.8e-21 75.3 0.0 8.1e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGG19105.1 - 2.4e-17 63.4 0.1 1.2e-16 61.1 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGG19105.1 - 4.7e-09 37.4 0.0 7.3e-08 33.5 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGG19105.1 - 9.1e-09 35.4 0.0 6.6e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EGG19105.1 - 2.7e-07 30.9 0.0 7e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EGG19105.1 - 7e-05 22.7 0.1 0.00021 21.1 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGG19105.1 - 0.00014 21.3 0.3 0.00059 19.3 0.3 1.9 1 1 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.10 EGG19106.1 - 1.5e-23 83.6 0.1 7.9e-23 81.3 0.0 2.3 2 0 0 2 2 2 1 KR domain ADH_zinc_N_2 PF13602.6 EGG19106.1 - 1.3e-10 42.4 0.0 1.2e-08 36.1 0.0 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGG19106.1 - 9.9e-08 32.0 0.0 6.2e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EGG19106.1 - 1.6e-06 28.4 0.0 4.6e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EGG19106.1 - 0.00012 21.9 0.1 0.00024 21.0 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RsgA_GTPase PF03193.16 EGG19106.1 - 0.032 14.1 0.0 0.55 10.1 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase ketoacyl-synt PF00109.26 EGG19107.1 - 1.7e-63 214.5 0.2 4.8e-63 213.1 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGG19107.1 - 6.7e-48 163.8 0.0 1.2e-47 163.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGG19107.1 - 8.6e-35 119.3 0.1 4e-34 117.2 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EGG19107.1 - 2.2e-24 86.3 0.0 3.5e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGG19107.1 - 1.9e-17 63.7 0.0 6e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EGG19107.1 - 2.2e-05 23.9 0.3 0.00011 21.7 0.3 2.0 1 1 0 1 1 1 1 Thiolase, N-terminal domain DUF4060 PF13269.6 EGG19107.1 - 0.12 12.4 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4060) DUF2431 PF10354.9 EGG19109.1 - 2.8e-18 66.8 0.0 4.4e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Toprim PF01751.22 EGG19109.1 - 0.18 12.0 1.4 0.98 9.7 0.1 2.4 2 2 0 2 2 2 0 Toprim domain DUF3439 PF11921.8 EGG19109.1 - 0.58 10.1 3.2 1 9.3 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ArfGap PF01412.18 EGG19110.1 - 8.2e-32 109.7 1.2 8.2e-32 109.7 1.2 4.1 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf Abhydrolase_1 PF00561.20 EGG19116.1 - 2.3e-05 24.2 0.1 3.7e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG19116.1 - 0.00014 22.5 0.0 0.00017 22.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG19116.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Glyco_hydro_25 PF01183.20 EGG19117.1 - 9e-09 35.8 3.5 1.4e-08 35.1 3.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 CDC73_C PF05179.14 EGG19118.1 - 0.048 13.4 0.1 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal GnHR_trans PF12369.8 EGG19118.1 - 0.14 13.0 0.0 0.31 11.9 0.0 1.5 1 0 0 1 1 1 0 Gonadotropin hormone receptor transmembrane region Nse4_C PF08743.10 EGG19119.1 - 0.041 14.1 0.2 0.17 12.1 0.2 2.1 1 0 0 1 1 1 0 Nse4 C-terminal Ank_2 PF12796.7 EGG19121.1 - 0.00025 21.6 0.1 3.1 8.4 0.0 4.3 4 1 1 5 5 5 1 Ankyrin repeats (3 copies) SUIM_assoc PF16619.5 EGG19121.1 - 0.0016 18.5 2.6 0.0056 16.7 2.6 2.0 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 PBP1_TM PF14812.6 EGG19121.1 - 0.0046 17.3 7.0 0.0046 17.3 7.0 2.1 2 1 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_4 PF13637.6 EGG19121.1 - 0.066 13.8 0.1 4.1 8.1 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19121.1 - 0.091 13.1 0.7 66 4.0 0.0 4.3 4 2 2 6 6 6 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG19122.1 - 1.7e-07 31.7 4.2 0.072 13.7 0.0 5.0 5 1 0 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19122.1 - 9.3e-06 26.1 0.9 0.5 11.0 0.0 5.1 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19122.1 - 0.001 19.3 0.0 11 6.5 0.0 5.0 4 1 1 5 5 5 1 Ankyrin repeats (many copies) DUF1041 PF06292.17 EGG19122.1 - 0.0061 17.0 8.0 0.48 10.8 0.0 4.6 4 0 0 4 4 4 2 Domain of Unknown Function (DUF1041) PBP1_TM PF14812.6 EGG19122.1 - 0.018 15.4 3.0 0.1 13.0 3.0 2.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NifQ PF04891.12 EGG19122.1 - 0.022 15.1 6.6 0.82 10.0 0.5 3.6 3 0 0 3 3 3 0 NifQ DUF3447 PF11929.8 EGG19122.1 - 0.11 12.4 17.3 0.37 10.8 0.2 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3447) FAM176 PF14851.6 EGG19122.1 - 0.12 12.1 6.4 0.42 10.3 6.4 1.9 1 0 0 1 1 1 0 FAM176 family DUF2682 PF10909.8 EGG19122.1 - 0.18 12.3 3.1 0.49 10.9 0.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2682) CENP-B_dimeris PF09026.10 EGG19122.1 - 1 9.8 6.4 3.3 8.2 6.4 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain EGF_2 PF07974.13 EGG19123.1 - 0.0087 16.4 10.1 0.032 14.6 10.1 2.1 1 0 0 1 1 1 1 EGF-like domain fn3 PF00041.21 EGG19123.1 - 0.02 15.2 7.3 0.66 10.4 0.1 4.5 4 1 0 4 4 4 0 Fibronectin type III domain Ank_2 PF12796.7 EGG19124.1 - 1.3e-06 28.9 2.4 0.0018 18.8 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19124.1 - 0.0047 17.5 2.1 1.6 9.4 0.0 5.0 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19124.1 - 0.035 14.4 1.6 15 6.1 0.0 4.7 3 2 1 4 4 4 0 Ankyrin repeats (many copies) OrfB_Zn_ribbon PF07282.11 EGG19128.1 - 3.5e-06 26.9 0.0 0.0023 17.8 0.0 3.1 2 0 0 2 2 2 2 Putative transposase DNA-binding domain DUF2992 PF11208.8 EGG19128.1 - 0.57 10.4 0.0 0.57 10.4 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Rho_N PF07498.12 EGG19128.1 - 3.5 7.6 5.3 5.5 7.0 0.3 3.4 4 0 0 4 4 4 0 Rho termination factor, N-terminal domain Ank_2 PF12796.7 EGG19129.1 - 0.022 15.3 0.1 0.057 14.0 0.0 1.7 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EGG19129.1 - 1.5 8.8 7.1 0.19 11.7 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) FNIP PF05725.12 EGG19131.1 - 0.00034 20.7 19.1 0.31 11.3 0.3 7.1 7 0 0 7 7 7 2 FNIP Repeat RE_LlaMI PF09562.10 EGG19131.1 - 0.034 13.7 0.5 0.053 13.1 0.5 1.2 1 0 0 1 1 1 0 LlaMI restriction endonuclease Ank_2 PF12796.7 EGG19132.1 - 7.3e-11 42.5 4.3 0.014 16.0 0.0 7.2 6 2 1 7 7 7 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19132.1 - 3.8e-07 30.5 5.9 0.043 14.4 0.0 7.7 7 3 3 10 10 10 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19132.1 - 8.4e-06 26.0 1.1 61 4.1 0.0 7.9 6 2 2 8 8 8 0 Ankyrin repeats (many copies) DUF1041 PF06292.17 EGG19132.1 - 0.0098 16.3 0.1 3.8 7.9 0.0 3.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) Transglycosylas PF06737.14 EGG19132.1 - 0.23 12.1 0.1 22 5.8 0.0 2.5 2 0 0 2 2 2 0 Transglycosylase-like domain PRP1_N PF06424.12 EGG19133.1 - 0.037 14.4 1.2 0.04 14.3 1.2 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal FYDLN_acid PF09538.10 EGG19133.1 - 6.3 7.5 9.1 86 3.9 9.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Ank_2 PF12796.7 EGG19134.1 - 1.5e-08 35.1 2.3 0.62 10.7 0.0 5.5 4 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG19134.1 - 0.042 14.4 0.0 1.9e+02 3.2 0.0 5.5 5 0 0 5 5 5 0 Ankyrin repeat Histone PF00125.24 EGG19135.1 - 3.3e-49 166.6 2.0 3.7e-49 166.4 2.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGG19135.1 - 1.6e-05 25.0 1.1 1.6e-05 25.0 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGG19135.1 - 0.00031 21.1 0.0 0.00049 20.4 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EGG19135.1 - 0.004 17.7 0.2 0.0048 17.5 0.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EGG19135.1 - 0.065 13.5 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGG19135.1 - 0.072 13.2 0.0 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit FNIP PF05725.12 EGG19136.1 - 9.6e-06 25.7 13.2 0.52 10.5 0.1 6.7 5 2 0 5 5 5 3 FNIP Repeat HigB-like_toxin PF05015.13 EGG19136.1 - 0.005 17.2 0.1 0.11 12.9 0.0 2.9 3 0 0 3 3 3 1 RelE-like toxin of type II toxin-antitoxin system HigB DUF5032 PF16435.5 EGG19137.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5032) FNIP PF05725.12 EGG19137.1 - 1.8 8.8 34.2 0.59 10.3 0.1 8.0 8 3 1 9 9 9 0 FNIP Repeat FNIP PF05725.12 EGG19138.1 - 1.5 9.1 21.2 0.3 11.3 0.6 6.3 5 2 3 8 8 8 0 FNIP Repeat FNIP PF05725.12 EGG19139.1 - 9.9e-05 22.4 20.6 0.13 12.5 0.1 7.3 5 2 1 6 6 6 4 FNIP Repeat FNIP PF05725.12 EGG19141.1 - 6.6e-07 29.4 7.1 1.8 8.8 0.0 7.5 4 3 1 6 6 6 3 FNIP Repeat PRORP PF16953.5 EGG19141.1 - 0.044 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein-only RNase P Rad4 PF03835.15 EGG19141.1 - 0.051 13.3 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain DUF960 PF06124.11 EGG19141.1 - 0.16 12.6 1.0 4.2 8.1 0.0 3.1 2 1 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) SUIM_assoc PF16619.5 EGG19142.1 - 0.0065 16.5 5.1 0.017 15.2 5.1 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 FNIP PF05725.12 EGG19142.1 - 0.032 14.4 43.8 0.24 11.6 1.0 7.9 5 2 1 7 7 7 0 FNIP Repeat Peptidase_C3 PF00548.20 EGG19142.1 - 0.12 12.3 1.6 0.44 10.4 0.4 2.3 2 0 0 2 2 2 0 3C cysteine protease (picornain 3C) LRR_5 PF13306.6 EGG19145.1 - 0.00026 21.0 1.8 0.00026 21.0 1.8 3.0 3 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 EGG19145.1 - 0.023 14.9 22.8 15 5.9 0.8 6.4 3 3 1 4 4 4 0 FNIP Repeat LRR_4 PF12799.7 EGG19145.1 - 4.2 7.9 29.3 1.9 9.0 0.1 6.9 5 3 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 EGG19146.1 - 0.13 12.7 26.5 0.88 10.1 0.0 9.5 8 4 2 10 10 10 0 Leucine Rich repeats (2 copies) FNIP PF05725.12 EGG19146.1 - 0.93 9.7 25.9 1.2 9.4 0.6 7.4 4 3 1 5 5 5 0 FNIP Repeat FNIP PF05725.12 EGG19147.1 - 2.7e-07 30.6 3.4 0.54 10.5 0.0 6.3 3 1 2 5 5 5 3 FNIP Repeat LRR_8 PF13855.6 EGG19148.1 - 0.013 15.3 0.5 0.013 15.3 0.5 4.9 5 1 1 6 6 6 0 Leucine rich repeat FNIP PF05725.12 EGG19148.1 - 0.075 13.2 0.2 0.075 13.2 0.2 5.7 7 0 0 7 7 7 0 FNIP Repeat FNIP PF05725.12 EGG19150.1 - 0.0018 18.4 19.9 2.9 8.1 1.2 6.7 7 1 0 7 7 7 4 FNIP Repeat DUF4768 PF15989.5 EGG19150.1 - 0.16 11.9 0.0 0.51 10.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4768) LRR_4 PF12799.7 EGG19152.1 - 3.8 8.1 9.9 3.7 8.1 0.1 3.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 EGG19153.1 - 0.016 15.6 18.4 0.5 10.9 0.3 7.2 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) FNIP PF05725.12 EGG19153.1 - 0.026 14.7 21.3 0.68 10.1 0.6 7.4 5 2 2 7 7 7 0 FNIP Repeat FNIP PF05725.12 EGG19155.1 - 0.013 15.6 17.9 0.13 12.4 2.2 5.8 4 1 1 5 5 5 0 FNIP Repeat F-box PF00646.33 EGG19156.1 - 0.011 15.6 2.5 0.036 14.0 2.5 1.9 1 0 0 1 1 1 0 F-box domain DivIVA PF05103.13 EGG19157.1 - 0.075 13.1 1.3 0.39 10.8 0.2 2.3 2 0 0 2 2 2 0 DivIVA protein DUF2779 PF11074.8 EGG19157.1 - 0.11 13.0 4.8 2.3 8.7 1.7 3.7 2 1 0 2 2 2 0 Domain of unknown function(DUF2779) CobA_CobO_BtuR PF02572.15 EGG19158.1 - 0.032 14.5 0.6 0.099 12.9 0.0 2.0 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Xpo1 PF08389.12 EGG19158.1 - 9.7 6.2 11.4 3 7.9 5.2 2.7 2 1 0 2 2 2 0 Exportin 1-like protein Ank_4 PF13637.6 EGG19159.1 - 0.0036 17.8 0.0 1.6 9.4 0.0 4.5 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19159.1 - 0.01 16.3 0.1 9.8 7.1 0.0 5.6 5 1 1 6 6 6 0 Ankyrin repeat Citrate_synt PF00285.21 EGG19160.1 - 3.7e-112 375.0 0.0 4.3e-112 374.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain MIEAP PF16026.5 EGG19162.1 - 0.0056 16.9 0.0 0.0056 16.9 0.0 3.2 2 1 1 3 3 3 1 Mitochondria-eating protein TSC22 PF01166.18 EGG19162.1 - 0.24 11.7 5.5 0.63 10.4 4.9 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family IFT20 PF14931.6 EGG19162.1 - 0.24 11.6 27.8 1.8 8.7 7.8 3.7 3 1 1 4 4 4 0 Intraflagellar transport complex B, subunit 20 Methyltransf_9 PF08003.11 EGG19162.1 - 0.35 9.7 4.9 0.35 9.7 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) bZIP_1 PF00170.21 EGG19162.1 - 0.97 9.6 8.3 0.41 10.8 3.8 2.5 1 1 1 2 2 2 0 bZIP transcription factor Fzo_mitofusin PF04799.13 EGG19162.1 - 3.6 7.1 13.5 0.47 10.0 6.2 2.6 1 1 1 2 2 2 0 fzo-like conserved region HSP70 PF00012.20 EGG19163.1 - 1.6e-05 23.3 0.0 3.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Hsp70 protein VWA_2 PF13519.6 EGG19163.1 - 0.0076 16.9 0.0 0.021 15.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain HSP70 PF00012.20 EGG19164.1 - 2.5e-11 42.5 0.2 3.9e-10 38.6 0.1 2.0 1 1 1 2 2 2 2 Hsp70 protein HSP70 PF00012.20 EGG19165.1 - 0.027 12.7 0.0 0.038 12.2 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Nop25 PF09805.9 EGG19167.1 - 0.00074 20.0 2.2 0.00074 20.0 2.2 2.8 3 0 0 3 3 3 1 Nucleolar protein 12 (25kDa) Dscam_C PF12355.8 EGG19168.1 - 1.6 9.7 5.6 0.33 11.9 0.9 2.0 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Ank_2 PF12796.7 EGG19169.1 - 1.8e-19 70.1 10.9 0.00074 20.1 0.1 7.4 4 1 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG19169.1 - 8.8e-16 56.4 8.3 0.72 10.6 0.0 11.1 11 0 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 EGG19169.1 - 1.6e-14 53.8 9.2 0.026 14.8 0.0 9.9 7 3 4 11 11 11 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG19169.1 - 1e-12 48.3 10.3 0.00011 22.7 0.0 7.9 7 2 1 9 9 9 3 Ankyrin repeats (many copies) DUF249 PF03158.13 EGG19169.1 - 2.8e-06 27.2 5.4 0.0048 16.6 0.1 3.5 3 1 0 3 3 3 2 Multigene family 530 protein Kelch_1 PF01344.25 EGG19170.1 - 8.4e-10 38.1 3.7 0.0025 17.3 0.0 4.8 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 EGG19170.1 - 6.3e-09 35.8 1.3 0.037 14.3 0.0 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 EGG19170.1 - 2.4e-08 33.8 10.9 1.1 9.3 0.0 6.0 6 1 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 EGG19170.1 - 3.2e-05 23.8 0.4 5 7.2 0.0 5.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.6 EGG19170.1 - 0.024 14.9 10.5 4.3 7.7 0.0 5.7 6 1 0 6 6 6 0 Galactose oxidase, central domain Tim54 PF11711.8 EGG19170.1 - 5.8 5.6 8.1 0.49 9.1 2.4 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 NST1 PF13945.6 EGG19170.1 - 9.5 6.3 23.6 1.7 8.7 4.5 2.9 3 0 0 3 3 3 0 Salt tolerance down-regulator CTP_transf_like PF01467.26 EGG19172.1 - 2.2e-08 34.4 0.0 8.3e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Cytidylyltransferase-like GNT-I PF03071.15 EGG19173.1 - 2.9e-83 280.0 6.6 3.1e-83 280.0 2.2 1.9 1 1 1 2 2 2 2 GNT-I family TMF_TATA_bd PF12325.8 EGG19173.1 - 0.0083 16.3 7.2 0.015 15.5 7.2 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding UPF0223 PF05256.12 EGG19173.1 - 0.027 14.8 2.2 0.065 13.6 2.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0223) FlxA PF14282.6 EGG19174.1 - 0.016 15.2 11.8 0.016 15.2 11.8 4.0 5 0 0 5 5 5 0 FlxA-like protein Sugarporin_N PF11471.8 EGG19174.1 - 0.048 13.6 0.5 0.093 12.7 0.5 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension UNC-79 PF14776.6 EGG19174.1 - 0.11 11.2 0.1 0.11 11.2 0.1 2.0 2 0 0 2 2 2 0 Cation-channel complex subunit UNC-79 PSI_PsaF PF02507.15 EGG19174.1 - 0.14 12.0 0.7 0.26 11.1 0.7 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III ABC_tran_CTD PF16326.5 EGG19174.1 - 0.19 12.0 2.8 0.39 11.0 2.8 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain FliJ PF02050.16 EGG19174.1 - 6.1 7.1 10.2 0.2 11.9 3.7 1.8 2 0 0 2 2 2 0 Flagellar FliJ protein ParA PF10609.9 EGG19175.1 - 7.6e-79 264.6 0.0 1e-78 264.2 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGG19175.1 - 1.4e-06 28.4 0.0 6.8e-06 26.2 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGG19175.1 - 5.8e-06 26.3 0.1 9.8e-05 22.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGG19175.1 - 0.00038 20.4 2.0 0.0047 16.8 0.3 2.7 2 1 0 2 2 2 1 RsgA GTPase ArsA_ATPase PF02374.15 EGG19175.1 - 0.0016 17.7 2.3 0.0037 16.5 0.2 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase MeaB PF03308.16 EGG19175.1 - 0.0063 15.5 0.1 0.012 14.6 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 EGG19175.1 - 0.0073 16.0 0.0 3.4 7.3 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein MipZ PF09140.11 EGG19175.1 - 0.0096 15.2 0.1 0.065 12.5 0.1 2.0 2 0 0 2 2 2 1 ATPase MipZ CBP_BcsQ PF06564.12 EGG19175.1 - 0.018 14.5 0.0 0.035 13.6 0.0 1.5 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 EGG19175.1 - 0.11 12.0 0.9 0.46 9.9 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 EGG19175.1 - 0.12 12.2 2.9 3.4 7.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Ribosomal_L7Ae PF01248.26 EGG19176.1 - 1e-21 76.5 0.7 1.9e-21 75.6 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rad52_Rad22 PF04098.15 EGG19177.1 - 2e-40 138.2 0.2 2e-40 138.2 0.2 1.4 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein Exo_endo_phos PF03372.23 EGG19178.1 - 1e-19 71.0 0.0 1.8e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_19 PF14559.6 EGG19178.1 - 8.6e-17 61.4 7.2 0.00059 20.3 0.1 7.0 6 1 2 8 8 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGG19178.1 - 5.4e-15 54.3 11.5 2.8e-06 27.1 0.0 9.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG19178.1 - 3.2e-12 45.6 11.9 0.00064 19.7 0.0 8.0 10 0 0 10 10 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG19178.1 - 3.1e-11 43.7 0.0 0.8 10.4 0.0 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG19178.1 - 2.2e-10 40.7 1.6 0.47 10.8 0.0 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG19178.1 - 5.6e-10 38.6 11.8 5.1e-05 22.9 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG19178.1 - 2.3e-09 37.3 1.2 0.45 11.5 0.7 7.6 6 2 2 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG19178.1 - 2.4e-09 37.3 12.0 0.0036 17.5 0.2 5.9 4 1 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGG19178.1 - 1.2e-08 35.0 12.5 0.27 12.0 0.0 8.2 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG19178.1 - 1.7e-07 31.2 0.3 20 5.9 0.0 7.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG19178.1 - 2.2e-06 27.3 10.4 0.075 13.1 0.1 6.2 7 1 1 8 8 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG19178.1 - 1.8e-05 24.3 0.0 1.6 8.4 0.2 5.1 5 0 0 5 5 5 1 TPR repeat TPR_20 PF14561.6 EGG19178.1 - 0.00012 22.4 1.6 1 9.7 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG19178.1 - 0.0004 20.5 0.1 0.21 11.7 1.3 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGG19178.1 - 0.0024 17.2 0.2 16 4.6 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG19178.1 - 0.003 17.6 0.8 0.038 14.1 0.2 3.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat FAT PF02259.23 EGG19178.1 - 0.048 12.9 0.1 0.14 11.3 0.1 1.8 1 0 0 1 1 1 0 FAT domain TPR_4 PF07721.14 EGG19178.1 - 0.073 13.7 1.1 57 4.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGG19178.1 - 0.17 11.8 1.0 62 3.7 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGG19178.1 - 0.24 11.8 3.1 2.5 8.5 0.0 3.0 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_3 PF07720.12 EGG19178.1 - 0.39 10.8 0.0 0.39 10.8 0.0 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat NARP1 PF12569.8 EGG19178.1 - 0.5 9.2 0.0 0.5 9.2 0.0 4.2 3 1 0 4 4 3 0 NMDA receptor-regulated protein 1 PI3K_1B_p101 PF10486.9 EGG19178.1 - 7.9 4.1 13.5 2.7 5.6 4.3 2.2 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF5600 PF18150.1 EGG19179.1 - 4e-11 43.4 0.1 7.9e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) DUF5600 PF18150.1 EGG19180.1 - 1.8e-41 141.1 0.3 5.1e-41 139.6 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 EGG19180.1 - 2.4e-21 75.6 0.0 7.8e-21 74.0 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 EGG19180.1 - 7.2e-14 52.2 0.0 1e-11 45.2 0.0 2.3 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 EGG19180.1 - 5.3e-13 48.6 0.1 1.2e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 EGG19180.1 - 3.7e-08 33.4 0.0 1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 EGG19180.1 - 6.5e-06 25.3 0.2 3.2e-05 23.2 0.1 2.4 2 0 0 2 2 2 1 EF hand Roc PF08477.13 EGG19180.1 - 0.00034 20.8 0.0 0.71 10.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 EGG19180.1 - 0.0079 16.0 0.1 0.047 13.6 0.1 2.4 1 0 0 1 1 1 1 EF-hand domain GTP_EFTU PF00009.27 EGG19180.1 - 0.016 14.8 0.0 0.087 12.3 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain EF-hand_5 PF13202.6 EGG19180.1 - 0.018 14.5 1.5 0.026 14.0 0.2 2.0 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 EGG19180.1 - 0.031 14.7 0.1 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair Ras PF00071.22 EGG19180.1 - 0.034 13.7 0.1 6.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Ras family Isochorismatase PF00857.20 EGG19180.1 - 0.054 13.7 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 Isochorismatase family EF-hand_8 PF13833.6 EGG19180.1 - 0.11 12.3 0.1 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair Gtr1_RagA PF04670.12 EGG19180.1 - 0.13 11.6 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_28 PF13521.6 EGG19180.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGG19180.1 - 0.17 11.9 0.1 0.44 10.5 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MID_MedPIWI PF18296.1 EGG19181.1 - 2.1e-26 93.3 3.7 2.1e-26 93.3 3.7 10.7 6 4 2 8 8 8 1 MID domain of medPIWI Med13_C PF06333.12 EGG19181.1 - 4.9e-24 85.2 2.5 4.9e-24 85.2 2.5 8.2 5 2 4 9 9 9 1 Mediator complex subunit 13 C-terminal domain ABC_tran PF00005.27 EGG19182.1 - 0.0007 20.1 0.5 0.0034 17.9 0.3 2.2 2 1 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 EGG19182.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 EGG19182.1 - 0.0014 17.9 1.2 0.0058 15.9 1.2 1.9 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGG19182.1 - 0.0053 16.8 0.1 0.016 15.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG19182.1 - 0.0056 16.6 0.1 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGG19182.1 - 0.0065 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGG19182.1 - 0.0087 15.9 0.4 0.03 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EGG19182.1 - 0.02 15.3 0.0 0.053 13.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG19182.1 - 0.034 14.5 0.0 0.19 12.1 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 EGG19182.1 - 0.051 14.1 0.1 0.051 14.1 0.1 3.6 4 0 0 4 4 4 0 AAA domain Dynamin_N PF00350.23 EGG19182.1 - 0.06 13.4 0.5 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 EGG19182.1 - 0.068 13.1 0.4 1.5 8.7 0.1 3.0 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.6 EGG19182.1 - 0.13 12.6 0.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 EGG19182.1 - 0.2 10.6 0.0 0.45 9.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) GBP PF02263.19 EGG19184.1 - 2.3e-34 118.8 0.1 2.6e-33 115.4 0.2 2.6 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EGG19184.1 - 3.7e-12 46.3 0.1 0.00047 20.2 0.0 3.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG19184.1 - 1.5e-06 28.2 0.1 0.16 11.9 0.0 3.7 4 0 0 4 4 4 2 RsgA GTPase ABC_tran PF00005.27 EGG19184.1 - 3.5e-06 27.6 0.4 0.018 15.6 0.0 3.0 3 0 0 3 3 2 2 ABC transporter TsaE PF02367.17 EGG19184.1 - 0.00048 20.1 0.0 0.42 10.6 0.0 3.3 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 EGG19184.1 - 0.00082 19.6 2.1 1.1 9.4 0.1 3.6 4 0 0 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGG19184.1 - 0.0037 17.0 0.1 1.4 8.7 0.0 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EGG19184.1 - 0.0081 16.7 0.0 0.3 11.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain KH_dom-like PF14714.6 EGG19184.1 - 0.0088 16.3 0.2 0.1 12.9 0.0 2.9 3 0 0 3 3 2 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal AAA_22 PF13401.6 EGG19184.1 - 0.03 14.6 0.1 3.8 7.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EGG19184.1 - 0.09 12.9 0.3 13 5.9 0.1 3.5 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EGG19184.1 - 0.092 13.2 0.7 9.5 6.7 0.3 3.2 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGG19184.1 - 0.15 12.4 0.0 23 5.3 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 EGG19184.1 - 0.86 10.0 4.1 7.5 7.0 0.0 4.0 5 0 0 5 5 3 0 RNA helicase Dynamin_N PF00350.23 EGG19184.1 - 0.96 9.5 4.6 5.1 7.1 0.0 3.5 4 0 0 4 4 3 0 Dynamin family DUF5344 PF17279.2 EGG19184.1 - 1.4 9.5 4.2 7.9 7.1 0.0 3.4 4 0 0 4 4 3 0 Family of unknown function (DUF5344) Patatin PF01734.22 EGG19185.1 - 2e-09 37.9 0.1 7.7e-07 29.5 0.1 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase zf-RING_5 PF14634.6 EGG19185.1 - 0.22 11.5 5.9 0.6 10.1 5.9 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EGG19185.1 - 1.4 8.9 6.6 3.6 7.5 6.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glycos_transf_4 PF00953.21 EGG19186.1 - 2e-32 112.4 13.5 6.1e-32 110.8 13.5 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 4 DUF3778 PF12620.8 EGG19187.1 - 0.69 9.5 0.0 0.69 9.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3778) Macoilin PF09726.9 EGG19187.1 - 3.7 6.0 15.5 4.4 5.8 15.5 1.1 1 0 0 1 1 1 0 Macoilin family DUF531 PF04407.12 EGG19188.1 - 0.085 12.9 0.1 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF531) Pox_I3 PF04661.12 EGG19188.1 - 1.7 7.7 10.2 1.7 7.7 0.1 3.3 3 0 0 3 3 3 0 Poxvirus I3 ssDNA-binding protein Aldedh PF00171.22 EGG19189.1 - 9.6e-130 433.2 0.1 1.1e-129 432.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.32 EGG19190.1 - 1.3e-12 47.9 17.7 0.00011 22.9 0.5 6.6 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG19190.1 - 3.3e-05 24.1 0.0 1.9 8.8 0.0 4.6 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGG19190.1 - 0.0077 16.7 0.3 67 4.2 0.0 4.2 5 0 0 5 5 5 0 PQQ-like domain FNIP PF05725.12 EGG19191.1 - 7.3e-07 29.3 11.2 0.084 13.1 0.3 6.5 5 1 1 6 6 6 3 FNIP Repeat Jnk-SapK_ap_N PF09744.9 EGG19191.1 - 0.014 15.7 4.4 0.03 14.6 4.4 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 EGG19191.1 - 0.064 13.3 2.4 0.13 12.4 2.4 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF496 PF04363.12 EGG19191.1 - 0.068 13.2 1.1 4.7 7.3 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF496) ADIP PF11559.8 EGG19191.1 - 0.14 12.2 5.2 0.29 11.2 5.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 EGG19191.1 - 0.37 11.2 5.1 6.8 7.1 0.6 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain BLOC1_2 PF10046.9 EGG19191.1 - 1.4 9.3 6.9 0.48 10.7 0.9 2.5 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3552 PF12072.8 EGG19191.1 - 1.6 8.1 5.4 0.33 10.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF1319 PF07028.11 EGG19191.1 - 3.9 7.7 6.4 7.5 6.8 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Endotoxin_N PF03945.14 EGG19193.1 - 0.0016 18.2 0.3 0.055 13.2 0.3 2.3 1 1 0 1 1 1 1 delta endotoxin, N-terminal domain DUF3179 PF11376.8 EGG19193.1 - 0.088 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3179) SurA_N_3 PF13624.6 EGG19193.1 - 0.24 11.2 3.2 0.13 12.1 0.5 2.0 2 1 0 2 2 2 0 SurA N-terminal domain DUF2680 PF10925.8 EGG19193.1 - 1.3 9.1 8.0 0.23 11.5 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) LRAT PF04970.13 EGG19194.1 - 0.032 14.5 2.7 0.45 10.8 2.7 2.4 1 1 0 1 1 1 0 Lecithin retinol acyltransferase Peptidase_C97 PF05903.14 EGG19194.1 - 0.07 13.0 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain DUF1068 PF06364.12 EGG19195.1 - 1.4 8.8 10.1 0.034 14.0 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) CSN8_PSD8_EIF3K PF10075.9 EGG19196.1 - 1.4e-30 106.1 0.1 7.7e-30 103.8 0.0 1.8 1 1 1 2 2 2 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 EGG19196.1 - 0.048 14.2 0.3 0.11 13.1 0.3 1.8 1 1 0 1 1 1 0 PCI domain GFA PF04828.14 EGG19197.1 - 2.6e-06 27.7 0.3 2.6e-06 27.7 0.3 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme FUR PF01475.19 EGG19197.1 - 0.17 12.0 0.8 0.29 11.3 0.8 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family zf-CSL PF05207.13 EGG19197.1 - 0.35 10.6 7.4 0.093 12.5 1.0 2.4 2 1 0 2 2 2 0 CSL zinc finger zf-4CXXC_R1 PF10497.9 EGG19198.1 - 9.9e-10 38.5 12.3 3.7e-09 36.7 12.3 1.9 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Sas10_Utp3 PF04000.15 EGG19199.1 - 2.8e-14 53.5 1.7 3.7e-14 53.1 0.1 2.0 1 1 1 2 2 2 1 Sas10/Utp3/C1D family DUF2513 PF10711.9 EGG19199.1 - 0.13 12.6 2.1 0.16 12.2 0.9 1.7 2 0 0 2 2 2 0 Hypothetical protein (DUF2513) Neur_chan_memb PF02932.16 EGG19199.1 - 0.78 9.7 3.9 0.96 9.5 3.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 EGG19199.1 - 2.1 7.5 3.6 2.8 7.1 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter WD40 PF00400.32 EGG19200.1 - 8.9e-58 190.9 8.8 4.3e-10 40.0 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG19200.1 - 3.3e-27 94.6 0.9 2.1e-06 27.9 0.0 6.2 1 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG19200.1 - 8e-12 45.4 0.5 2.2e-06 27.7 0.1 4.1 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGG19200.1 - 9.6e-07 28.4 0.1 0.0048 16.3 0.0 3.0 2 2 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 EGG19200.1 - 7.8e-06 25.1 0.5 0.71 8.8 0.0 4.0 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EGG19200.1 - 0.00011 20.9 0.0 0.0032 16.1 0.0 2.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain Frtz PF11768.8 EGG19200.1 - 0.00063 18.2 0.0 0.22 9.8 0.0 2.5 1 1 2 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Macoilin PF09726.9 EGG19200.1 - 0.0011 17.7 7.1 0.0015 17.2 7.1 1.2 1 0 0 1 1 1 1 Macoilin family PD40 PF07676.12 EGG19200.1 - 0.0014 18.6 1.0 3.4 7.7 0.1 4.0 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.6 EGG19200.1 - 0.0054 16.8 0.1 1.5 8.9 0.0 3.3 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region GIT_CC PF16559.5 EGG19200.1 - 0.076 12.9 2.5 0.18 11.7 2.5 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor IMUP PF15761.5 EGG19200.1 - 4.1 8.1 12.6 13 6.5 12.6 1.9 1 0 0 1 1 1 0 Immortalisation up-regulated protein Peptidase_M1 PF01433.20 EGG19201.1 - 2.9e-74 249.3 2.6 4.8e-74 248.6 2.6 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGG19201.1 - 2e-70 237.9 0.0 3.9e-70 236.9 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGG19201.1 - 4.2e-51 173.8 0.3 4.2e-51 173.8 0.3 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_M48 PF01435.18 EGG19201.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M48 BSP PF04450.12 EGG19201.1 - 0.25 11.1 1.6 0.76 9.5 0.0 2.4 3 0 0 3 3 3 0 Peptidase of plants and bacteria Gaa1 PF04114.14 EGG19202.1 - 3.2e-99 333.2 9.9 7.9e-99 331.9 9.9 1.6 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF1385 PF07136.11 EGG19202.1 - 0.0017 17.7 0.5 0.0037 16.6 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1385) FAM176 PF14851.6 EGG19202.1 - 0.015 14.9 1.2 0.2 11.3 0.0 2.6 3 0 0 3 3 3 0 FAM176 family Tho2 PF11262.8 EGG19202.1 - 0.058 12.6 0.0 0.058 12.6 0.0 2.6 3 0 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 OrsD PF12013.8 EGG19202.1 - 0.2 12.1 0.1 0.49 10.9 0.1 1.6 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF4589 PF15252.6 EGG19202.1 - 0.3 11.1 8.2 0.17 11.8 0.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4589) Peptidase_S49_N PF08496.10 EGG19202.1 - 0.82 9.7 6.9 5 7.2 1.4 2.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal GP41 PF00517.17 EGG19202.1 - 3.9 7.3 7.2 1e+02 2.7 0.2 3.0 2 1 1 3 3 3 0 Retroviral envelope protein Aminotran_5 PF00266.19 EGG19203.1 - 5.4e-39 134.2 0.0 1.4e-38 132.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Dicty_spore_N PF04562.12 EGG19203.1 - 5.9e-18 65.6 20.2 4e-17 63.0 20.2 2.4 1 1 0 1 1 1 1 Dictyostelium spore coat protein, N terminus PALP PF00291.25 EGG19203.1 - 0.026 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGG19203.1 - 0.091 12.1 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family SPX PF03105.19 EGG19203.1 - 0.41 10.5 10.9 0.6 10.0 10.9 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 EGG19203.1 - 0.76 8.6 14.0 1.1 8.1 14.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain UDPGP PF01704.18 EGG19204.1 - 1e-143 478.9 9.1 6.5e-75 252.3 1.1 2.1 2 0 0 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase FNIP PF05725.12 EGG19205.1 - 0.00021 21.4 21.3 0.14 12.4 0.1 6.8 8 0 0 8 8 8 3 FNIP Repeat FNIP PF05725.12 EGG19206.1 - 0.0055 16.9 21.6 15 5.8 0.0 7.7 6 2 0 6 6 6 4 FNIP Repeat PRORP PF16953.5 EGG19206.1 - 0.012 15.1 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein-only RNase P Mso1_Sec1_bdg PF14475.6 EGG19208.1 - 0.031 13.9 3.5 0.16 11.6 0.6 3.1 2 0 0 2 2 2 0 Sec1-binding region of Mso1 CDT1_C PF16679.5 EGG19208.1 - 0.13 12.7 2.8 0.66 10.4 2.2 2.5 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain TMEM208_SND2 PF05620.11 EGG19208.1 - 3.5 7.4 5.8 6.9 6.4 5.8 1.5 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 FNIP PF05725.12 EGG19209.1 - 0.00021 21.4 24.2 0.16 12.1 0.0 7.8 6 3 0 7 7 7 3 FNIP Repeat LuxC PF05893.14 EGG19209.1 - 0.12 11.4 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) FNIP PF05725.12 EGG19210.1 - 0.054 13.7 14.3 8.1 6.7 0.2 6.0 5 1 2 7 7 7 0 FNIP Repeat CAF1-p150_N PF15557.6 EGG19210.1 - 0.19 11.7 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to PCNA LRR_4 PF12799.7 EGG19210.1 - 0.44 11.1 19.6 10 6.7 0.2 7.0 6 2 1 7 7 7 0 Leucine Rich repeats (2 copies) FNIP PF05725.12 EGG19211.1 - 4.7 7.5 28.3 1.3 9.2 2.1 7.0 4 2 2 6 6 6 0 FNIP Repeat LRR_4 PF12799.7 EGG19211.1 - 7 7.2 28.2 4.8 7.8 1.6 7.1 5 2 4 9 9 9 0 Leucine Rich repeats (2 copies) fn3 PF00041.21 EGG19213.1 - 7.5e-12 45.4 26.9 0.0011 19.3 0.7 9.6 10 0 0 10 10 10 5 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 EGG19213.1 - 0.00038 21.0 41.3 1.1 9.8 0.7 9.7 6 2 1 9 9 9 6 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 EGG19213.1 - 0.39 11.1 15.2 18 5.8 0.1 6.5 6 0 0 6 6 6 0 Uncharacterised conserved protein (DUF2369) EGF_2 PF07974.13 EGG19213.1 - 1.4 9.4 15.6 0.24 11.8 11.0 2.2 2 0 0 2 2 2 0 EGF-like domain Cnd2 PF05786.14 EGG19215.1 - 2.3e-108 363.9 45.3 2.3e-108 363.9 45.3 4.2 2 2 2 4 4 4 1 Condensin complex subunit 2 DUF498 PF04430.14 EGG19216.1 - 2.1e-26 92.1 0.0 3.3e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Orf78 PF06024.12 EGG19216.1 - 0.007 16.7 1.6 0.015 15.6 0.1 2.2 2 0 0 2 2 2 1 Orf78 (ac78) WAP PF00095.21 EGG19216.1 - 0.53 10.7 14.5 1.6 9.2 14.5 1.8 1 1 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Peptidase_C10 PF01640.17 EGG19216.1 - 1.6 9.0 6.3 0.14 12.5 1.1 1.9 2 1 1 3 3 3 0 Peptidase C10 family PA14 PF07691.12 EGG19217.1 - 3.8e-07 30.0 0.4 1.7e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 PA14 domain Dicty_CTDC PF00526.18 EGG19217.1 - 0.00023 21.0 16.9 0.0013 18.6 7.8 12.7 14 0 0 14 14 14 6 Dictyostelium (slime mold) repeat Dicty_CTDC PF00526.18 EGG19218.1 - 3.2e-12 46.1 30.5 5.3e-08 32.6 9.1 12.6 13 0 0 13 13 13 5 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGG19218.1 - 6.2e-06 26.1 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF2613 PF11021.8 EGG19218.1 - 1.6 8.9 6.8 3.8 7.7 6.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF525 PF04379.14 EGG19219.1 - 2.1e-24 85.6 0.0 5.9e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 ApaG domain F-box-like PF12937.7 EGG19219.1 - 0.0041 17.0 0.5 0.0041 17.0 0.5 1.8 2 0 0 2 2 2 1 F-box-like Elongin_A PF06881.11 EGG19219.1 - 0.005 17.3 0.2 0.01 16.3 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A SUKH_6 PF14568.6 EGG19219.1 - 0.05 14.0 0.0 0.9 10.0 0.0 2.9 3 1 0 3 3 3 0 SMI1-KNR4 cell-wall F-box_4 PF15966.5 EGG19219.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 F-box DNA_pol_alpha_N PF12254.8 EGG19219.1 - 0.37 10.9 1.8 0.77 9.9 1.8 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal EGF_2 PF07974.13 EGG19220.1 - 1.9e-09 37.7 31.4 8.8e-06 26.0 10.5 3.2 2 0 0 2 2 2 2 EGF-like domain LRR19-TM PF15176.6 EGG19220.1 - 3.7e-06 26.9 0.1 0.062 13.3 0.0 2.6 2 0 0 2 2 2 2 Leucine-rich repeat family 19 TM domain hEGF PF12661.7 EGG19220.1 - 8e-06 26.3 26.9 0.0013 19.3 10.1 3.2 2 0 0 2 2 2 2 Human growth factor-like EGF EGF PF00008.27 EGG19220.1 - 0.00011 22.4 25.8 0.013 15.8 10.9 2.8 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGG19220.1 - 0.00015 21.7 17.9 0.0037 17.3 2.9 3.0 2 0 0 2 2 2 2 Tenascin EGF domain EB PF01683.18 EGG19220.1 - 0.00031 21.0 20.7 0.019 15.2 4.8 3.1 3 0 0 3 3 3 2 EB module DUF3844 PF12955.7 EGG19220.1 - 0.00045 20.3 14.0 0.14 12.3 4.6 3.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3844) I-EGF_1 PF18372.1 EGG19220.1 - 0.0081 16.2 21.8 0.054 13.6 7.2 2.8 2 0 0 2 2 2 2 Integrin beta epidermal growth factor like domain 1 Protocadherin PF08374.11 EGG19220.1 - 0.047 13.7 3.3 5.1 7.0 0.0 2.8 3 0 0 3 3 3 0 Protocadherin LRR_4 PF12799.7 EGG19220.1 - 0.052 14.0 42.2 8.2 7.0 4.9 12.0 9 2 3 12 12 12 0 Leucine Rich repeats (2 copies) DUF4479 PF14794.6 EGG19220.1 - 0.12 12.3 0.2 10 6.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) PSI_integrin PF17205.3 EGG19220.1 - 0.2 11.4 3.0 18 5.2 0.1 3.0 2 0 0 2 2 2 0 Integrin plexin domain LRR_9 PF14580.6 EGG19220.1 - 1.2 8.6 7.6 1 8.8 0.9 3.6 2 1 1 3 3 3 0 Leucine-rich repeat RXT2_N PF08595.11 EGG19221.1 - 0.0086 16.1 38.0 0.13 12.3 0.6 4.5 4 0 0 4 4 4 3 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 EGG19221.1 - 0.027 14.8 5.2 0.027 14.8 5.2 5.0 4 2 0 4 4 4 0 Centromere protein B dimerisation domain Ank_5 PF13857.6 EGG19222.1 - 1.5e-27 95.3 9.0 0.012 15.9 0.0 11.0 5 3 7 12 12 12 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG19222.1 - 2.3e-27 95.4 11.8 3.2e-06 27.6 0.1 6.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19222.1 - 1e-23 83.4 5.4 0.0017 18.9 0.0 8.5 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19222.1 - 7.4e-15 53.6 6.9 0.48 11.1 0.1 12.0 11 2 2 13 13 13 2 Ankyrin repeat Ank PF00023.30 EGG19222.1 - 8e-06 26.1 2.4 16 6.2 0.2 8.0 4 3 2 6 6 6 1 Ankyrin repeat DUF5049 PF16468.5 EGG19222.1 - 2.6e-05 24.0 2.8 8.4 6.4 0.0 6.8 5 2 2 7 7 7 2 Domain of unknown function (DUF5049) Clathrin PF00637.20 EGG19222.1 - 0.0099 15.8 3.2 1.8 8.5 1.3 2.8 2 0 0 2 2 2 2 Region in Clathrin and VPS XPG_I_2 PF12813.7 EGG19222.1 - 0.04 13.4 0.4 0.56 9.6 0.0 2.3 2 0 0 2 2 2 0 XPG domain containing Pinin_SDK_memA PF04696.13 EGG19224.1 - 2 8.5 9.6 4.6 7.3 9.6 1.7 1 1 0 1 1 1 0 pinin/SDK/memA/ protein conserved region PH_5 PF15405.6 EGG19225.1 - 4.6 7.3 9.5 3.7 7.7 1.6 2.8 2 0 0 2 2 2 0 Pleckstrin homology domain FNIP PF05725.12 EGG19226.1 - 3e-83 273.7 20.3 1.2e-14 54.1 0.0 9.7 5 1 3 10 10 10 9 FNIP Repeat RNA_lig_T4_1 PF09511.10 EGG19226.1 - 3.2e-39 135.1 0.0 8.6e-39 133.7 0.0 1.7 1 0 0 1 1 1 1 RNA ligase Pkinase PF00069.25 EGG19226.1 - 1.5e-11 44.2 10.8 3.6e-11 42.9 3.6 3.0 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19226.1 - 0.00054 19.3 0.2 0.00096 18.5 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM154 PF15102.6 EGG19227.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 TMEM154 protein family DUF4449 PF14613.6 EGG19229.1 - 2.3e-06 27.8 3.4 6.2e-06 26.4 3.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) LBP_BPI_CETP PF01273.25 EGG19229.1 - 0.0038 16.8 0.0 0.013 15.1 0.0 1.8 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain FNIP PF05725.12 EGG19230.1 - 3.6e-185 600.0 63.6 1.1e-15 57.5 0.6 17.6 9 4 2 18 18 18 15 FNIP Repeat Pkinase PF00069.25 EGG19230.1 - 1.3e-21 77.1 0.6 2.2e-21 76.4 0.6 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19230.1 - 2.9e-06 26.8 0.0 0.00041 19.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Motilin_assoc PF04643.12 EGG19230.1 - 0.00066 19.5 0.3 95 3.0 0.0 7.7 8 2 2 10 10 10 0 Motilin/ghrelin-associated peptide CPBP PF02517.16 EGG19230.1 - 0.014 15.7 7.5 23 5.5 0.1 6.5 4 3 2 6 6 6 0 CPBP intramembrane metalloprotease AbiJ_NTD5 PF18865.1 EGG19230.1 - 0.11 12.3 2.8 7.3 6.5 0.0 5.3 4 2 3 7 7 7 0 AbiJ N-terminal domain 5 DUF2207 PF09972.9 EGG19231.1 - 0.088 11.6 3.5 0.065 12.0 1.8 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5305 PF17231.2 EGG19231.1 - 0.12 11.7 2.1 0.16 11.4 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5305) Kinesin PF00225.23 EGG19232.1 - 3e-105 351.8 1.6 3e-105 351.8 1.6 3.6 4 1 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EGG19232.1 - 2.8e-23 82.5 0.0 2.8e-23 82.5 0.0 4.5 3 2 1 4 4 4 1 Microtubule binding BRCT_3 PF18428.1 EGG19233.1 - 1.1e-22 80.0 1.6 7e-22 77.4 0.2 2.9 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT PF00533.26 EGG19233.1 - 1.2e-11 44.8 0.8 1.4e-05 25.3 0.0 3.2 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGG19233.1 - 5.5e-10 39.5 0.2 0.00015 22.1 0.0 3.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EGG19233.1 - 0.33 10.8 0.0 0.33 10.8 0.0 4.6 5 2 0 5 5 5 0 Regulator of Ty1 transposition protein 107 BRCT domain Peptidase_C1 PF00112.23 EGG19234.1 - 4.2e-20 72.8 0.5 1e-19 71.5 0.5 1.5 1 1 0 1 1 1 1 Papain family cysteine protease PIF1 PF05970.14 EGG19237.1 - 4.6e-45 154.4 2.4 1.9e-33 116.2 1.5 3.0 2 1 1 3 3 2 2 PIF1-like helicase AAA_30 PF13604.6 EGG19237.1 - 4.1e-20 72.3 0.0 6.3e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG19237.1 - 3.1e-12 47.1 0.1 1.1e-11 45.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGG19237.1 - 3e-05 23.6 1.8 6.1e-05 22.6 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EGG19237.1 - 0.00031 21.0 0.3 0.0018 18.5 0.3 2.3 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EGG19237.1 - 0.00099 18.9 0.2 0.0031 17.3 0.2 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EGG19237.1 - 0.002 17.9 5.3 0.65 9.7 0.0 3.6 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EGG19237.1 - 0.0029 17.5 0.6 0.017 15.0 0.6 2.3 1 1 0 1 1 1 1 Helicase Mg_chelatase PF01078.21 EGG19237.1 - 0.008 15.6 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DEAD PF00270.29 EGG19237.1 - 0.0081 15.9 0.3 0.9 9.3 0.4 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.6 EGG19237.1 - 0.013 15.9 0.4 0.028 14.8 0.4 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EGG19237.1 - 0.017 15.5 0.1 0.036 14.5 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EGG19237.1 - 0.03 13.4 0.2 0.049 12.7 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 EGG19237.1 - 0.046 13.7 0.4 0.49 10.4 0.4 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 EGG19237.1 - 0.077 12.4 0.2 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein NTPase_1 PF03266.15 EGG19237.1 - 0.25 11.2 5.0 2.9 7.8 2.7 3.1 2 1 0 2 2 2 0 NTPase TPR_2 PF07719.17 EGG19238.1 - 2.5e-06 27.2 0.1 5.6e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG19238.1 - 3.8e-06 26.5 0.3 8.7e-06 25.3 0.3 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG19238.1 - 0.0016 18.7 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat EMC3_TMCO1 PF01956.16 EGG19239.1 - 1.3e-38 132.5 2.7 1.4e-38 132.3 2.7 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like MTP18 PF10558.9 EGG19239.1 - 0.013 15.5 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) MapZ_EC1 PF18041.1 EGG19239.1 - 0.038 14.2 3.8 0.56 10.5 0.3 2.1 1 1 1 2 2 2 0 MapZ extracellular domain 1 Synaptobrevin PF00957.21 EGG19239.1 - 2.7 7.8 6.1 0.21 11.4 0.7 2.0 2 0 0 2 2 2 0 Synaptobrevin AAA PF00004.29 EGG19240.1 - 3.7e-41 140.6 0.0 6.3e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG19240.1 - 1.8e-08 34.0 0.1 3.2e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EGG19240.1 - 3e-07 30.3 0.3 6.4e-07 29.2 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EGG19240.1 - 7.4e-06 26.3 0.2 0.0023 18.2 0.2 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGG19240.1 - 2.1e-05 23.8 0.0 4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 EGG19240.1 - 2.9e-05 24.3 0.0 6.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGG19240.1 - 6.2e-05 23.0 0.9 0.00051 20.0 0.3 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGG19240.1 - 0.00038 20.9 0.2 0.0026 18.2 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGG19240.1 - 0.00077 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EGG19240.1 - 0.0043 16.4 0.1 0.22 10.8 0.1 2.3 1 1 1 2 2 2 1 KaiC NB-ARC PF00931.22 EGG19240.1 - 0.0076 15.5 0.0 0.73 9.0 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain IstB_IS21 PF01695.17 EGG19240.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EGG19240.1 - 0.018 15.4 0.0 0.048 14.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 EGG19240.1 - 0.018 14.2 0.1 0.042 13.0 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 EGG19240.1 - 0.025 14.4 0.0 0.078 12.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGG19240.1 - 0.026 14.2 0.3 0.13 11.9 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 EGG19240.1 - 0.03 14.3 0.1 0.23 11.4 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AAA_33 PF13671.6 EGG19240.1 - 0.042 14.0 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGG19240.1 - 0.047 13.4 0.2 0.12 12.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EGG19240.1 - 0.05 13.1 0.1 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 EGG19240.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF1128 PF06569.11 EGG19240.1 - 0.073 13.1 0.1 0.84 9.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) Mg_chelatase PF01078.21 EGG19240.1 - 0.076 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EGG19240.1 - 0.084 12.4 0.7 1.1 8.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 EGG19240.1 - 0.085 12.9 0.1 0.64 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGG19240.1 - 0.09 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGG19240.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EGG19240.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGG19240.1 - 1.7 8.6 4.3 3.3 7.6 0.1 3.2 2 2 1 4 4 4 0 NTPase WD40 PF00400.32 EGG19241.1 - 1.2e-27 95.5 1.3 0.00013 22.7 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG19241.1 - 1.1e-12 48.1 0.2 9.8e-05 22.6 0.0 4.6 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG19241.1 - 3.9e-10 39.2 3.4 5.5e-05 22.3 0.1 3.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH_TPL PF17814.1 EGG19241.1 - 9e-08 31.6 0.6 2e-07 30.5 0.6 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Nup160 PF11715.8 EGG19241.1 - 4.3e-06 25.7 1.6 0.62 8.6 0.1 4.7 2 2 2 5 5 5 2 Nucleoporin Nup120/160 HTH_46 PF15977.5 EGG19241.1 - 0.00076 19.4 0.0 0.0026 17.8 0.0 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA binding PALB2_WD40 PF16756.5 EGG19241.1 - 0.062 12.2 1.2 7.9 5.3 0.1 3.2 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 EGG19241.1 - 0.091 12.5 0.4 6.7 6.4 0.0 3.2 3 0 0 3 3 3 0 TUP1-like enhancer of split Nucleoporin_N PF08801.11 EGG19241.1 - 0.093 11.5 2.1 4.2 6.0 0.0 3.3 2 2 0 2 2 2 0 Nup133 N terminal like WSD PF15613.6 EGG19243.1 - 0.02 15.3 3.1 0.02 15.3 3.1 2.0 1 1 1 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF3398 PF11878.8 EGG19243.1 - 0.04 14.4 1.1 0.04 14.4 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3398) DUF2944 PF11161.8 EGG19243.1 - 0.06 13.2 2.2 0.1 12.5 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) IF-2B PF01008.17 EGG19243.1 - 5.6 6.1 14.7 0.8 8.9 7.9 2.0 1 1 1 2 2 2 0 Initiation factor 2 subunit family AAA_7 PF12775.7 EGG19246.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MobB PF03205.14 EGG19246.1 - 0.027 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.15 EGG19246.1 - 0.083 12.9 0.1 0.083 12.9 0.1 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGG19246.1 - 0.12 12.7 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGG19246.1 - 0.14 12.5 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain FB_lectin PF07367.11 EGG19246.1 - 0.14 12.1 0.2 0.24 11.4 0.2 1.3 1 0 0 1 1 1 0 Fungal fruit body lectin CAP_GLY PF01302.25 EGG19247.1 - 2.3e-23 81.9 0.6 3.8e-23 81.3 0.6 1.3 1 0 0 1 1 1 1 CAP-Gly domain zf-C4H2 PF10146.9 EGG19247.1 - 0.27 11.5 27.7 0.035 14.4 19.2 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein Peptidase_M13 PF01431.21 EGG19247.1 - 0.51 9.9 8.0 0.65 9.6 0.7 2.3 2 0 0 2 2 2 0 Peptidase family M13 LMBR1 PF04791.16 EGG19247.1 - 0.85 8.4 14.9 1.1 8.0 14.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein WDCP PF15390.6 EGG19247.1 - 2.4 6.4 18.6 3.2 6.0 18.6 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family YtxH PF12732.7 EGG19247.1 - 2.7 8.6 8.0 4.6 7.8 0.2 3.0 1 1 1 2 2 2 0 YtxH-like protein DUF4407 PF14362.6 EGG19247.1 - 3 7.1 16.4 5 6.4 16.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EGG19247.1 - 3.3 6.5 36.0 16 4.2 35.7 2.2 1 1 0 1 1 1 0 Spc7 kinetochore protein ApoO PF09769.9 EGG19247.1 - 4.6 7.2 6.3 24 4.9 0.3 2.6 2 1 0 2 2 2 0 Apolipoprotein O DUF4200 PF13863.6 EGG19247.1 - 9.4 6.7 45.1 4 7.9 22.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 EGG19247.1 - 9.6 6.5 10.8 4.1e+03 -1.9 10.8 2.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CAP_GLY PF01302.25 EGG19248.1 - 9.9e-17 60.7 0.1 1.6e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain ALIX_LYPXL_bnd PF13949.6 EGG19248.1 - 0.0078 15.6 27.0 0.13 11.5 13.6 2.6 1 1 1 2 2 2 2 ALIX V-shaped domain binding to HIV DUF1664 PF07889.12 EGG19248.1 - 0.035 14.1 16.0 0.18 11.8 3.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 EGG19248.1 - 0.15 11.8 31.6 0.075 12.8 11.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Occludin_ELL PF07303.13 EGG19248.1 - 0.33 11.7 25.0 2 9.2 5.1 3.8 2 1 2 4 4 4 0 Occludin homology domain DUF3584 PF12128.8 EGG19248.1 - 0.53 7.7 25.3 0.72 7.3 25.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FAM184 PF15665.5 EGG19248.1 - 0.53 10.0 29.9 0.22 11.3 25.9 2.0 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Lebercilin PF15619.6 EGG19248.1 - 0.53 9.9 31.5 0.86 9.2 31.5 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 EGG19248.1 - 0.68 8.8 29.5 0.24 10.2 25.7 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EGG19248.1 - 0.96 9.5 30.7 0.91 9.6 22.8 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 EGG19248.1 - 2.4 8.6 30.4 0.46 10.9 25.3 2.0 1 1 1 2 2 2 0 Fez1 KxDL PF10241.9 EGG19248.1 - 2.4 8.5 27.4 0.2 11.9 10.7 4.0 1 1 3 4 4 4 0 Uncharacterized conserved protein HAUS-augmin3 PF14932.6 EGG19248.1 - 2.7 7.5 25.5 12 5.4 10.5 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 HMMR_C PF15908.5 EGG19248.1 - 2.8 8.2 23.5 3.6 7.8 3.8 3.6 1 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal THP2 PF09432.10 EGG19248.1 - 3.6 7.6 20.9 0.3 11.2 8.4 2.7 1 1 1 2 2 2 0 Tho complex subunit THP2 Exonuc_VII_L PF02601.15 EGG19248.1 - 4 6.9 26.3 0.23 11.0 13.0 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit NeuB PF03102.14 EGG19248.1 - 4.4 6.7 12.1 1.8 8.0 8.6 1.9 1 1 1 2 2 2 0 NeuB family DUF4337 PF14235.6 EGG19248.1 - 4.5 7.4 22.4 0.28 11.3 5.7 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4337) GAS PF13851.6 EGG19248.1 - 5.1 6.4 37.1 0.54 9.6 8.5 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.13 EGG19248.1 - 5.2 6.2 29.4 8.6 5.5 9.0 2.2 1 1 1 2 2 2 0 TMPIT-like protein PSI_PsaF PF02507.15 EGG19248.1 - 8.2 6.2 8.2 5 6.9 1.3 2.6 2 1 1 3 3 3 0 Photosystem I reaction centre subunit III Ank_2 PF12796.7 EGG19249.1 - 0.018 15.6 0.1 0.62 10.7 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) DUF1664 PF07889.12 EGG19251.1 - 0.0093 16.0 15.8 0.14 12.2 2.9 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) ALIX_LYPXL_bnd PF13949.6 EGG19251.1 - 0.01 15.2 28.2 0.19 11.0 12.5 2.8 1 1 2 3 3 3 0 ALIX V-shaped domain binding to HIV DUF4201 PF13870.6 EGG19251.1 - 0.12 12.1 33.2 0.029 14.1 12.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.12 EGG19251.1 - 1.8 8.6 29.7 1.6 8.8 21.3 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 EGG19251.1 - 2.6 7.5 25.7 0.21 11.1 13.0 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF4473 PF14747.6 EGG19251.1 - 2.6 8.6 12.0 1.7 9.3 1.8 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4473) Sec34 PF04136.15 EGG19251.1 - 5.1 7.0 25.1 15 5.5 7.5 3.6 2 1 1 3 3 3 0 Sec34-like family TMPIT PF07851.13 EGG19251.1 - 5.3 6.2 29.5 5.5 6.1 9.7 2.4 1 1 1 2 2 2 0 TMPIT-like protein Peptidase_S8 PF00082.22 EGG19252.1 - 3.4e-33 115.2 0.0 8.3e-33 113.9 0.0 1.6 1 1 0 1 1 1 1 Subtilase family GCOM2 PF15328.6 EGG19252.1 - 0.011 16.1 3.6 0.011 16.1 3.6 3.0 3 0 0 3 3 3 0 Putative GRINL1B complex locus protein 2 DUF4350 PF14258.6 EGG19252.1 - 0.053 14.0 0.0 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Frizzled PF01534.17 EGG19252.1 - 0.22 10.5 2.7 0.12 11.4 0.2 1.7 2 0 0 2 2 2 0 Frizzled/Smoothened family membrane region WBP-1 PF11669.8 EGG19252.1 - 0.44 11.2 2.3 1.5 9.5 0.1 2.8 2 1 0 2 2 2 0 WW domain-binding protein 1 CcmD PF04995.14 EGG19252.1 - 0.96 9.6 4.6 2.1 8.5 4.6 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) STE3 PF02076.15 EGG19252.1 - 1.3 8.1 12.4 1.5 7.9 0.3 3.0 3 0 0 3 3 3 0 Pheromone A receptor EphA2_TM PF14575.6 EGG19252.1 - 3.1 8.7 4.7 1.7 9.6 0.3 2.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Sugar_tr PF00083.24 EGG19253.1 - 1e-85 288.3 43.6 6.6e-85 285.7 43.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG19253.1 - 1.1e-31 110.0 44.4 2e-23 82.9 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGG19253.1 - 7.9e-06 24.6 5.7 7.9e-06 24.6 5.7 2.1 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EGG19253.1 - 1.7e-05 24.3 8.7 1.7e-05 24.3 8.7 2.9 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB Apq12 PF12716.7 EGG19253.1 - 2.7 8.0 10.4 0.27 11.2 2.7 3.3 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis DUF21 PF01595.20 EGG19253.1 - 3.9 7.2 16.0 1.5 8.5 7.1 2.7 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain AGT PF11440.8 EGG19255.1 - 0.0034 16.5 0.2 0.005 15.9 0.2 1.2 1 0 0 1 1 1 1 DNA alpha-glucosyltransferase ERGIC_N PF13850.6 EGG19255.1 - 0.036 14.4 0.1 0.29 11.5 0.1 2.3 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 EGG19257.1 - 4.8e-75 252.3 0.0 5.6e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19257.1 - 7.8e-40 136.8 0.0 9.6e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGG19257.1 - 9.6e-05 21.8 0.1 0.00013 21.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGG19257.1 - 0.026 14.1 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EGG19257.1 - 0.036 13.4 0.0 0.46 9.7 0.0 2.4 1 1 1 2 2 2 0 Kinase-like APH PF01636.23 EGG19257.1 - 0.086 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family IU_nuc_hydro PF01156.19 EGG19258.1 - 3.7e-78 263.2 0.5 5.1e-78 262.7 0.5 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CAP PF00188.26 EGG19258.1 - 3.8e-17 63.3 0.1 9.6e-17 62.0 0.1 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ins145_P3_rec PF08709.11 EGG19258.1 - 0.042 13.1 0.0 0.092 11.9 0.0 1.5 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor zf-C3HC4_3 PF13920.6 EGG19259.1 - 1.2e-07 31.5 14.0 2.3e-07 30.5 14.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG19259.1 - 0.0025 17.6 13.0 0.005 16.7 13.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGG19259.1 - 0.0086 16.4 17.2 0.022 15.1 17.2 1.7 1 0 0 1 1 1 1 Ring finger domain Leuk-A4-hydro_C PF09127.11 EGG19259.1 - 0.01 15.9 0.9 0.041 13.9 0.9 2.1 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal SPRY PF00622.28 EGG19259.1 - 0.077 13.1 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 SPRY domain zf-C3HC4 PF00097.25 EGG19259.1 - 2.1 8.3 18.2 6.8 6.6 18.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG19259.1 - 2.6 8.1 15.2 8.7 6.4 15.2 2.0 1 0 0 1 1 1 0 zinc-RING finger domain Clat_adaptor_s PF01217.20 EGG19260.1 - 2.7e-23 82.5 1.2 4.1e-18 65.7 0.4 2.0 1 1 1 2 2 2 2 Clathrin adaptor complex small chain FNIP PF05725.12 EGG19261.1 - 0.035 14.3 30.4 0.099 12.8 0.4 8.0 7 2 5 12 12 12 0 FNIP Repeat Ank_2 PF12796.7 EGG19262.1 - 0.00016 22.2 0.2 0.14 12.8 0.3 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19262.1 - 0.0016 19.0 1.5 13 6.5 0.0 4.7 3 2 1 4 4 4 2 Ankyrin repeats (many copies) S6PP_C PF08472.10 EGG19262.1 - 0.0017 18.2 1.2 0.0083 16.0 0.4 2.5 2 1 1 3 3 3 1 Sucrose-6-phosphate phosphohydrolase C-terminal GyrI-like PF06445.15 EGG19262.1 - 0.11 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 GyrI-like small molecule binding domain FNIP PF05725.12 EGG19263.1 - 2e-05 24.7 27.3 0.012 15.8 0.9 8.7 7 1 2 9 9 9 6 FNIP Repeat FNIP PF05725.12 EGG19264.1 - 2.6e-07 30.7 55.1 0.018 15.2 0.8 11.2 8 2 5 13 13 13 9 FNIP Repeat F-box-like PF12937.7 EGG19264.1 - 0.016 15.1 0.7 1.5 8.8 0.1 2.8 2 0 0 2 2 2 0 F-box-like DUF1374 PF07118.11 EGG19265.1 - 0.051 14.1 0.6 0.1 13.1 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) F-box-like PF12937.7 EGG19266.1 - 0.0034 17.2 0.0 0.0099 15.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF5640 PF18692.1 EGG19268.1 - 0.033 14.2 0.5 0.033 14.2 0.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5640) PEPCK_GTP PF00821.18 EGG19269.1 - 6.4e-176 584.5 0.2 8.4e-176 584.1 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 EGG19269.1 - 4.1e-105 350.2 0.0 5.4e-105 349.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain PEPCK_ATP PF01293.20 EGG19269.1 - 0.017 13.8 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Biotin_lipoyl_2 PF13533.6 EGG19269.1 - 0.12 12.3 0.6 1.8 8.5 0.6 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like Ank_2 PF12796.7 EGG19270.1 - 1.4e-21 76.8 0.4 6e-10 39.6 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGG19270.1 - 5.8e-20 70.8 0.1 5.8e-06 26.5 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EGG19270.1 - 1.5e-19 70.1 0.1 5.4e-08 33.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19270.1 - 1.1e-16 60.7 0.0 5.8e-08 32.9 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19270.1 - 2.2e-16 58.3 0.0 2.4e-05 24.4 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EGG19271.1 - 1.2e-32 112.3 4.4 6.5e-08 33.1 0.0 5.4 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19271.1 - 1.3e-32 111.7 6.7 1.3e-05 25.6 0.0 7.3 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19271.1 - 4.7e-30 103.2 10.9 1.8e-05 24.9 0.1 10.6 2 2 9 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19271.1 - 1.4e-15 55.8 4.5 0.93 10.3 0.0 8.9 9 1 1 10 10 10 5 Ankyrin repeat Ank PF00023.30 EGG19271.1 - 3.9e-10 39.7 0.6 6.7 7.3 0.1 8.3 3 2 6 9 9 9 2 Ankyrin repeat Ank_2 PF12796.7 EGG19273.1 - 5.1e-22 78.3 7.7 7.7e-05 23.2 0.2 6.6 1 1 8 9 9 9 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG19273.1 - 1.4e-20 73.1 4.3 0.0051 17.1 0.1 9.7 6 3 4 10 10 10 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG19273.1 - 5.3e-20 71.5 9.5 0.0014 19.2 0.0 8.3 5 3 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19273.1 - 1.4e-08 34.3 5.3 5.3 8.0 0.0 9.6 11 0 0 11 11 11 2 Ankyrin repeat Ank PF00023.30 EGG19273.1 - 0.0056 17.1 4.0 99 3.6 0.0 7.2 7 3 1 8 8 8 0 Ankyrin repeat DUF5049 PF16468.5 EGG19273.1 - 0.031 14.2 1.4 15 5.6 0.0 4.6 4 2 2 6 6 6 0 Domain of unknown function (DUF5049) YmaF PF12788.7 EGG19273.1 - 0.061 13.9 4.2 7.1 7.2 0.0 3.5 3 1 0 3 3 3 0 YmaF family DSPc PF00782.20 EGG19275.1 - 2.7e-28 98.4 1.4 3.4e-28 98.1 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG19275.1 - 0.00093 18.8 1.7 0.0011 18.6 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EGG19275.1 - 0.013 15.8 1.0 0.13 12.6 0.0 2.3 2 0 0 2 2 2 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 EGG19275.1 - 0.055 13.6 1.1 0.81 9.8 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate Aa_trans PF01490.18 EGG19277.1 - 9.2e-09 34.5 37.4 1.6e-08 33.7 37.4 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Colicin_K PF17500.2 EGG19277.1 - 0.03 14.9 0.3 0.03 14.9 0.3 4.1 3 2 1 5 5 5 0 Colicin-K DUF3099 PF11298.8 EGG19277.1 - 2.8 8.1 7.2 2.4 8.3 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) HlyIII PF03006.20 EGG19278.1 - 0.27 10.9 1.0 0.43 10.3 1.0 1.3 1 0 0 1 1 1 0 Haemolysin-III related FNIP PF05725.12 EGG19279.1 - 0.026 14.7 6.7 2.1 8.6 0.1 4.6 4 1 1 5 5 5 0 FNIP Repeat FNIP PF05725.12 EGG19283.1 - 1.6e-05 25.0 10.4 0.00049 20.2 4.3 3.2 2 1 1 3 3 3 3 FNIP Repeat DUF3623 PF12291.8 EGG19283.1 - 0.21 10.8 0.1 0.3 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) FNIP PF05725.12 EGG19285.1 - 2.3e-05 24.5 4.5 0.0026 17.9 0.5 6.4 4 2 3 7 7 7 5 FNIP Repeat FNIP PF05725.12 EGG19286.1 - 0.021 15.0 4.7 0.021 15.0 4.7 7.4 7 2 1 8 8 8 0 FNIP Repeat FNIP PF05725.12 EGG19287.1 - 0.022 14.9 21.1 0.34 11.1 0.8 7.2 6 2 1 7 7 7 0 FNIP Repeat FXa_inhibition PF14670.6 EGG19289.1 - 4.4e-158 513.2 412.2 2e-09 37.5 12.6 21.2 21 0 0 21 21 21 19 Coagulation Factor Xa inhibitory site cEGF PF12662.7 EGG19289.1 - 1.5e-116 379.7 204.6 9.5e-08 31.8 2.6 22.5 22 2 0 22 22 22 19 Complement Clr-like EGF-like EGF_CA PF07645.15 EGG19289.1 - 6.5e-91 298.3 351.6 5.4e-06 26.5 7.2 21.6 22 0 0 22 22 22 19 Calcium-binding EGF domain EGF_3 PF12947.7 EGG19289.1 - 2.9e-23 81.7 402.7 0.029 14.5 11.7 21.7 21 0 0 21 21 21 19 EGF domain EGF_2 PF07974.13 EGG19289.1 - 0.00014 22.1 13.3 0.00014 22.1 13.3 22.2 4 2 17 21 21 21 2 EGF-like domain Maf_N PF08383.11 EGG19289.1 - 0.066 13.0 8.8 1.4e+02 2.4 0.0 8.5 10 0 0 10 10 10 0 Maf N-terminal region FXa_inhibition PF14670.6 EGG19290.1 - 5.8e-26 90.5 73.5 4e-10 39.8 10.9 7.6 9 1 0 9 9 9 4 Coagulation Factor Xa inhibitory site cEGF PF12662.7 EGG19290.1 - 1.4e-14 53.6 63.9 1.4e-05 24.9 3.2 8.7 7 2 0 7 7 7 4 Complement Clr-like EGF-like EGF_CA PF07645.15 EGG19290.1 - 5e-13 49.0 60.9 1.9e-05 24.7 9.5 7.4 7 1 1 8 8 8 4 Calcium-binding EGF domain TIG PF01833.24 EGG19290.1 - 1.8e-05 24.7 4.6 1.8e-05 24.7 4.6 4.3 3 1 1 4 4 4 1 IPT/TIG domain EGF_2 PF07974.13 EGG19290.1 - 0.00058 20.2 12.2 0.00058 20.2 12.2 7.3 3 1 3 6 6 6 2 EGF-like domain DUF3042 PF11240.8 EGG19290.1 - 0.045 13.8 0.6 0.087 12.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Sec63 PF02889.16 EGG19291.1 - 6.2e-161 533.5 0.4 1.3e-83 280.1 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGG19291.1 - 9.7e-44 149.2 0.6 7.4e-24 84.5 0.2 4.5 4 0 0 4 4 4 3 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EGG19291.1 - 4.1e-37 126.7 4.5 3.9e-36 123.6 3.6 2.7 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 EGG19291.1 - 1.3e-17 64.3 2.4 5.1e-12 46.1 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGG19291.1 - 2.6e-12 47.1 0.6 3e-06 27.5 0.0 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 EGG19291.1 - 2.9e-06 27.1 1.2 0.0026 17.5 0.0 3.1 4 0 0 4 4 4 2 AAA domain Pox_I6 PF04595.13 EGG19292.1 - 0.091 11.7 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus I6-like family zf_Rg PF17915.1 EGG19294.1 - 0.14 11.6 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Reverse gyrase zinc finger PQ-loop PF04193.14 EGG19295.1 - 1.2e-08 34.5 5.4 2.2e-08 33.7 0.7 2.9 3 0 0 3 3 3 1 PQ loop repeat ThrE PF06738.12 EGG19295.1 - 0.0033 16.8 3.7 0.0059 16.0 3.7 1.4 1 0 0 1 1 1 1 Putative threonine/serine exporter SP24 PF16504.5 EGG19295.1 - 0.008 16.2 5.1 0.63 10.1 0.6 4.0 4 0 0 4 4 4 1 Putative virion membrane protein of plant and insect virus Peptidase_S8 PF00082.22 EGG19296.1 - 1.8e-20 73.4 1.3 1.8e-20 73.4 1.3 2.6 2 1 0 2 2 2 1 Subtilase family Cons_hypoth95 PF03602.15 EGG19296.1 - 0.11 12.2 2.4 0.17 11.5 1.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Cyclin_N PF00134.23 EGG19298.1 - 0.0011 18.7 0.8 0.0011 18.7 0.8 2.4 2 2 0 2 2 2 1 Cyclin, N-terminal domain DZR PF12773.7 EGG19298.1 - 0.0075 16.3 3.0 0.018 15.1 3.0 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 EGG19298.1 - 0.032 13.9 2.3 0.077 12.7 2.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EGG19298.1 - 0.17 11.3 1.2 0.45 10.0 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 EGG19298.1 - 0.49 10.6 4.3 1 9.6 2.8 2.2 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like BioY PF02632.14 EGG19299.1 - 1.5e-36 125.4 12.9 1.5e-36 125.4 12.9 1.5 2 0 0 2 2 2 1 BioY family DUF2407 PF10302.9 EGG19299.1 - 0.17 12.4 0.0 0.29 11.7 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Folate_carrier PF01770.18 EGG19300.1 - 0.0096 14.7 0.6 0.016 14.0 0.6 1.2 1 0 0 1 1 1 1 Reduced folate carrier MRNIP PF15749.5 EGG19300.1 - 0.29 11.9 8.0 5.5 7.8 3.5 2.5 2 0 0 2 2 2 0 MRN-interacting protein Secretin_N_2 PF07655.13 EGG19300.1 - 0.59 10.7 8.6 0.2 12.2 4.4 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain FNIP PF05725.12 EGG19301.1 - 1.6e-08 34.6 14.4 0.65 10.2 0.0 10.2 9 3 1 10 10 10 5 FNIP Repeat F-box-like PF12937.7 EGG19301.1 - 0.12 12.3 0.1 0.38 10.7 0.1 1.8 1 0 0 1 1 1 0 F-box-like zf-C3HC4_2 PF13923.6 EGG19302.1 - 3.2e-10 39.7 7.8 6.7e-10 38.6 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG19302.1 - 2.8e-09 36.7 8.3 8.3e-09 35.2 8.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG19302.1 - 6.2e-09 36.1 9.5 6.2e-09 36.1 9.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGG19302.1 - 1.9e-06 27.7 6.4 1.9e-06 27.7 6.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGG19302.1 - 5.1e-06 26.7 6.0 1.7e-05 25.0 6.0 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGG19302.1 - 7.4e-06 25.9 2.6 7.4e-06 25.9 2.6 2.6 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGG19302.1 - 0.00017 21.4 7.4 0.00017 21.4 7.4 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGG19302.1 - 0.0052 16.9 8.9 0.0052 16.9 8.9 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGG19302.1 - 0.0087 15.9 2.8 0.02 14.8 2.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EGG19302.1 - 0.014 15.3 7.4 0.014 15.3 7.4 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGG19302.1 - 0.042 13.9 1.9 0.093 12.8 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGG19302.1 - 0.1 12.4 6.2 0.33 10.8 6.2 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EGG19302.1 - 0.21 11.3 8.5 0.51 10.1 8.5 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 EGG19302.1 - 0.36 11.0 5.7 0.9 9.7 5.7 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Methyltransf_25 PF13649.6 EGG19303.1 - 5.5e-18 65.5 0.0 1.1e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG19303.1 - 6.5e-17 61.6 0.0 1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EGG19303.1 - 1.5e-16 60.8 0.0 1.2e-15 57.9 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG19303.1 - 1.4e-14 54.1 0.0 2.1e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG19303.1 - 1.3e-08 35.4 0.0 1.3e-07 32.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG19303.1 - 4e-08 33.3 0.0 7.1e-08 32.4 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_20 PF12147.8 EGG19303.1 - 1.6e-05 24.2 0.0 2.3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.9 EGG19303.1 - 8.3e-05 22.4 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_8 PF05148.15 EGG19303.1 - 0.00036 20.5 0.0 0.00052 19.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase PCMT PF01135.19 EGG19303.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EGG19303.1 - 0.0041 16.7 0.1 0.0068 16.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 EGG19303.1 - 0.0059 16.4 0.0 0.0081 15.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 EGG19303.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase TehB PF03848.14 EGG19303.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.12 EGG19303.1 - 0.016 14.3 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Cons_hypoth95 PF03602.15 EGG19303.1 - 0.055 13.1 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 DUF938 PF06080.12 EGG19303.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.13 EGG19303.1 - 0.078 12.4 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EGG19303.1 - 0.08 13.0 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ank_2 PF12796.7 EGG19304.1 - 2.6e-13 50.4 1.2 0.00063 20.3 0.0 4.3 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19304.1 - 6.9e-10 39.3 2.3 0.11 13.1 0.0 6.3 5 3 2 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19304.1 - 0.00025 21.3 0.0 78 3.8 0.0 5.7 5 2 1 6 6 6 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19304.1 - 0.00039 20.7 0.3 1.2e+02 3.8 0.0 6.9 9 0 0 9 9 9 0 Ankyrin repeat Ank PF00023.30 EGG19304.1 - 0.0097 16.3 0.0 9.5 6.9 0.0 4.1 4 1 1 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EGG19305.1 - 0.00048 20.4 0.1 0.032 14.6 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 EGG19305.1 - 0.0098 15.8 1.2 0.14 12.2 0.9 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EGG19305.1 - 0.03 14.9 0.0 0.43 11.2 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) GATA PF00320.27 EGG19307.1 - 3.3e-16 58.6 4.1 2.3e-15 55.9 4.1 2.7 1 0 0 1 1 1 1 GATA zinc finger Paired_CXXCH_1 PF09699.10 EGG19307.1 - 6.4 6.6 12.1 1.3 8.9 1.4 3.8 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) Ank_2 PF12796.7 EGG19308.1 - 2.7e-18 66.3 4.0 1.5e-05 25.5 0.0 3.9 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19308.1 - 9.3e-17 61.2 3.7 6.7e-05 23.4 0.0 5.1 4 2 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19308.1 - 9.2e-07 28.7 0.0 15 6.6 0.0 6.9 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 EGG19308.1 - 1.5e-06 28.4 6.4 5.8 7.4 0.0 6.8 3 2 4 7 7 7 2 Ankyrin repeats (many copies) DUF249 PF03158.13 EGG19308.1 - 0.075 12.7 2.0 0.18 11.5 0.1 2.3 2 1 0 2 2 2 0 Multigene family 530 protein Ank PF00023.30 EGG19308.1 - 0.22 12.0 0.6 1.4e+02 3.1 0.0 4.4 3 2 1 4 4 4 0 Ankyrin repeat CNOT1_HEAT PF16418.5 EGG19308.1 - 0.26 11.4 1.3 29 4.7 0.0 3.5 2 2 2 4 4 4 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Phage_lysozyme2 PF18013.1 EGG19308.1 - 0.51 10.3 4.7 2.6 8.0 4.7 2.3 1 1 0 1 1 1 0 Phage tail lysozyme FA_hydroxylase PF04116.13 EGG19309.1 - 4.5e-18 65.9 15.3 6.3e-18 65.4 15.3 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Sec20 PF03908.13 EGG19310.1 - 0.075 13.0 0.6 0.32 10.9 0.6 2.1 1 1 0 1 1 1 0 Sec20 gp45-slide_C PF09116.10 EGG19312.1 - 0.00011 22.3 9.2 1.9 8.6 0.1 6.5 7 0 0 7 7 7 3 gp45 sliding clamp, C terminal fn3 PF00041.21 EGG19312.1 - 0.055 13.8 0.1 0.055 13.8 0.1 13.9 14 0 0 14 14 14 0 Fibronectin type III domain SurA_N_3 PF13624.6 EGG19312.1 - 0.62 9.8 3.0 1.2 8.9 0.3 2.9 2 0 0 2 2 2 0 SurA N-terminal domain EGF_2 PF07974.13 EGG19313.1 - 0.00078 19.8 5.7 0.0019 18.5 5.7 1.7 1 0 0 1 1 1 1 EGF-like domain DUF3844 PF12955.7 EGG19313.1 - 0.0093 16.1 0.7 0.033 14.3 0.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF PF00008.27 EGG19313.1 - 0.037 14.3 3.0 0.14 12.5 3.0 2.0 1 0 0 1 1 1 0 EGF-like domain Glyco_hydro_30C PF17189.4 EGG19313.1 - 0.062 13.5 0.2 0.062 13.5 0.2 3.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain EB PF01683.18 EGG19313.1 - 0.11 12.8 3.6 0.32 11.3 3.6 1.7 1 0 0 1 1 1 0 EB module DUF4745 PF15923.5 EGG19313.1 - 0.12 12.4 5.1 2 8.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) EGF_Tenascin PF18720.1 EGG19313.1 - 0.23 11.5 4.3 0.55 10.4 4.3 1.6 1 0 0 1 1 1 0 Tenascin EGF domain hEGF PF12661.7 EGG19313.1 - 4 8.2 9.3 3.1 8.6 6.5 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF Toxin_2 PF00451.19 EGG19313.1 - 9.4 6.6 7.9 26 5.2 7.9 1.8 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 EGF_2 PF07974.13 EGG19314.1 - 0.0015 18.8 5.9 0.0039 17.5 5.9 1.7 1 0 0 1 1 1 1 EGF-like domain DUF3844 PF12955.7 EGG19314.1 - 0.0066 16.6 1.2 0.023 14.8 1.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) DUF2403 PF10290.9 EGG19314.1 - 0.011 16.2 0.2 3.9 8.0 0.1 3.1 2 0 0 2 2 2 0 Glycine-rich protein domain (DUF2403) LRR_8 PF13855.6 EGG19314.1 - 0.039 13.7 0.1 0.039 13.7 0.1 3.8 4 0 0 4 4 4 0 Leucine rich repeat EGF PF00008.27 EGG19314.1 - 0.068 13.5 2.6 0.19 12.1 2.6 1.7 1 0 0 1 1 1 0 EGF-like domain EB PF01683.18 EGG19314.1 - 0.14 12.4 3.3 0.36 11.2 3.3 1.6 1 0 0 1 1 1 0 EB module DUF5451 PF17532.2 EGG19314.1 - 0.16 12.2 0.7 4 7.7 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5451) EGF_Tenascin PF18720.1 EGG19314.1 - 0.5 10.5 6.1 1.2 9.2 6.1 1.7 1 0 0 1 1 1 0 Tenascin EGF domain hEGF PF12661.7 EGG19314.1 - 2.2 9.0 5.6 6.1 7.6 5.6 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF Glyco_hydro_38N PF01074.22 EGG19315.1 - 1.5e-74 250.9 0.5 3.1e-74 249.9 0.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 EGG19315.1 - 4.3e-14 52.4 0.0 8.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 EGG19315.1 - 2.4e-13 50.7 0.0 4.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro38C2 PF17677.1 EGG19315.1 - 2e-07 31.0 0.0 5.6e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain EB PF01683.18 EGG19316.1 - 0.021 15.1 13.7 0.021 15.1 13.7 5.6 3 2 1 5 5 5 0 EB module Med13_C PF06333.12 EGG19316.1 - 0.62 9.3 7.9 1 8.6 7.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain TMEM154 PF15102.6 EGG19316.1 - 1.3 8.9 5.1 2.4 8.1 5.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Peptidase_C12 PF01088.21 EGG19317.1 - 8.1e-62 208.7 0.1 8.1e-62 208.7 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pkinase PF00069.25 EGG19318.1 - 2.9e-66 223.5 0.0 4.1e-59 200.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19318.1 - 3.3e-49 167.5 0.0 3.6e-46 157.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG19318.1 - 6.1e-05 22.0 0.9 8.4e-05 21.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGG19318.1 - 6.6e-05 22.4 0.2 0.00029 20.3 0.0 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EGG19318.1 - 0.03 14.2 0.0 0.064 13.2 0.1 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG19318.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WH1 PF00568.23 EGG19319.1 - 2.2e-22 79.1 0.6 3.6e-22 78.4 0.6 1.3 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 EGG19319.1 - 8.7e-17 61.2 0.9 1.8e-16 60.2 0.1 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain WH2 PF02205.20 EGG19319.1 - 8.7e-07 28.6 0.5 1.6e-06 27.7 0.5 1.4 1 0 0 1 1 1 1 WH2 motif RCC1 PF00415.18 EGG19322.1 - 2.6e-86 284.1 25.8 3.8e-15 56.2 0.3 9.2 9 0 0 9 9 9 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG19322.1 - 1.7e-35 120.1 32.0 7.2e-09 35.2 0.7 8.3 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Clathrin PF00637.20 EGG19322.1 - 0.059 13.2 18.3 0.09 12.7 0.3 4.1 4 0 0 4 4 4 0 Region in Clathrin and VPS DNA_RNApol_7kD PF03604.13 EGG19323.1 - 1.6e-16 59.7 7.2 2.1e-16 59.3 7.2 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit MCM_OB PF17207.3 EGG19323.1 - 0.0056 16.5 0.5 0.0058 16.5 0.5 1.2 1 0 0 1 1 1 1 MCM OB domain zinc_ribbon_13 PF09855.9 EGG19323.1 - 0.0098 16.0 0.4 0.0098 16.0 0.4 1.9 1 1 1 2 2 2 1 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DZR PF12773.7 EGG19323.1 - 0.091 12.8 2.6 0.13 12.4 2.6 1.2 1 0 0 1 1 1 0 Double zinc ribbon Vps36-NZF-N PF16988.5 EGG19324.1 - 0.021 14.2 0.9 0.082 12.3 0.1 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF3972 PF13118.6 EGG19324.1 - 0.059 13.8 0.9 0.11 12.9 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) HEM4 PF02602.15 EGG19325.1 - 3.6e-22 78.9 0.0 1.3e-19 70.5 0.0 2.1 2 0 0 2 2 2 2 Uroporphyrinogen-III synthase HemD UbiA PF01040.18 EGG19325.1 - 1.6e-17 63.6 9.9 2.4e-17 63.1 9.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Apolipoprotein PF01442.18 EGG19326.1 - 0.0014 18.5 5.1 0.0028 17.5 5.1 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EGG19326.1 - 0.022 14.9 8.2 0.053 13.6 8.2 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Spore_SspJ PF09575.10 EGG19326.1 - 0.043 14.2 2.2 0.043 14.2 2.2 2.3 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) YtxH PF12732.7 EGG19326.1 - 0.05 14.1 12.7 70 4.1 12.5 3.1 1 1 0 1 1 1 0 YtxH-like protein SKA2 PF16740.5 EGG19326.1 - 0.052 13.3 3.0 0.29 10.9 0.3 2.4 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF948 PF06103.11 EGG19326.1 - 0.062 13.6 4.1 2.1 8.7 0.7 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3175 PF11373.8 EGG19326.1 - 0.12 12.5 0.4 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3175) DUF1664 PF07889.12 EGG19326.1 - 0.16 12.0 2.3 0.3 11.1 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) PIN_8 PF18476.1 EGG19326.1 - 0.17 11.7 4.0 0.19 11.5 2.8 1.7 1 1 1 2 2 2 0 PIN like domain AT_hook PF02178.19 EGG19326.1 - 0.19 11.7 4.9 0.71 9.9 4.9 2.0 1 0 0 1 1 1 0 AT hook motif DUF4854 PF16146.5 EGG19326.1 - 0.3 11.4 5.6 0.82 10.0 0.6 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4854) DUF2884 PF11101.8 EGG19326.1 - 0.32 10.5 6.0 0.94 8.9 6.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Muted PF14942.6 EGG19326.1 - 0.54 10.6 10.3 0.02 15.2 4.6 1.5 2 0 0 2 2 1 0 Organelle biogenesis, Muted-like protein DUF883 PF05957.13 EGG19326.1 - 0.76 10.4 9.8 2.3 8.9 0.5 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Tektin PF03148.14 EGG19326.1 - 4.8 5.8 9.4 0.35 9.6 0.1 2.5 2 1 1 3 3 3 0 Tektin family Med28 PF11594.8 EGG19327.1 - 0.076 13.1 0.1 0.093 12.8 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 28 LEA_4 PF02987.16 EGG19327.1 - 0.27 11.3 1.1 0.37 10.9 0.3 1.7 2 0 0 2 2 2 0 Late embryogenesis abundant protein Pex14_N PF04695.13 EGG19327.1 - 0.46 11.1 7.8 0.57 10.8 7.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Acetyltransf_3 PF13302.7 EGG19328.1 - 1.9e-20 73.9 0.0 2.3e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG19328.1 - 0.0011 19.2 0.1 0.0015 18.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGG19328.1 - 0.026 14.5 0.2 0.089 12.8 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein Ribosomal_L27A PF00828.19 EGG19329.1 - 7.6e-34 117.1 3.1 1.9e-33 115.8 0.7 2.1 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Hexapep PF00132.24 EGG19330.1 - 2.7e-12 45.9 23.6 3.8e-07 29.6 3.2 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) CDT1_C PF16679.5 EGG19330.1 - 0.19 12.2 0.0 0.32 11.5 0.0 1.3 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Hexapep_2 PF14602.6 EGG19330.1 - 2.5 7.9 20.9 1.9 8.3 0.3 3.7 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase MPLKIP PF15502.6 EGG19331.1 - 7.8e-05 22.8 14.2 0.0002 21.5 14.2 2.0 1 1 0 1 1 1 1 M-phase-specific PLK1-interacting protein SSP160 PF06933.11 EGG19331.1 - 0.35 9.0 6.8 0.44 8.7 6.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PI3K_P85_iSH2 PF16454.5 EGG19332.1 - 0.032 13.8 10.7 0.017 14.8 3.6 2.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SNARE PF05739.19 EGG19332.1 - 0.14 12.2 5.5 0.063 13.3 2.8 1.9 2 0 0 2 2 2 0 SNARE domain TMPIT PF07851.13 EGG19332.1 - 2 7.6 7.1 2.3 7.4 0.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein YojJ PF10372.9 EGG19332.1 - 2.2 8.5 5.2 15 5.8 0.1 3.3 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus CHD5 PF04420.14 EGG19332.1 - 3 7.7 6.7 21 5.0 1.3 2.7 3 0 0 3 3 3 0 CHD5-like protein T3SSipB PF16535.5 EGG19332.1 - 4.7 7.7 10.1 0.18 12.3 0.9 2.5 2 1 0 2 2 2 0 Type III cell invasion protein SipB Laminin_II PF06009.12 EGG19332.1 - 5.9 6.9 14.5 0.12 12.4 1.6 3.2 2 1 1 3 3 3 0 Laminin Domain II Ank_2 PF12796.7 EGG19333.1 - 2.9e-14 53.4 4.6 5.8e-05 23.6 0.0 6.0 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG19333.1 - 4.8e-10 39.5 0.1 0.39 11.1 0.0 6.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 EGG19333.1 - 5.6e-07 29.4 7.8 0.015 15.2 2.1 5.0 5 1 0 5 5 5 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EGG19333.1 - 1.2e-06 28.9 3.4 15 6.3 0.0 7.4 4 3 5 9 9 9 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19333.1 - 8.5e-05 22.7 2.4 15 6.6 0.0 7.6 8 1 1 9 9 9 1 Ankyrin repeat Gelsolin PF00626.22 EGG19334.1 - 6.1e-39 131.8 0.1 8.1e-07 28.9 0.0 7.7 5 0 0 5 5 5 5 Gelsolin repeat VHP PF02209.19 EGG19334.1 - 7.1e-12 45.2 0.5 2e-11 43.8 0.5 1.9 1 0 0 1 1 1 1 Villin headpiece domain RRM_1 PF00076.22 EGG19335.1 - 1.8e-16 59.7 0.0 2.6e-15 56.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 EGG19335.1 - 6.5e-10 39.7 0.1 7.9e-09 36.2 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 EGG19335.1 - 0.018 15.1 0.0 0.071 13.2 0.0 2.1 1 0 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 EGG19335.1 - 0.031 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif RCDG1 PF15725.5 EGG19335.1 - 0.049 14.1 0.2 0.049 14.1 0.2 4.9 4 1 1 5 5 5 0 Renal cancer differentiation gene 1 protein Cwf_Cwc_15 PF04889.12 EGG19336.1 - 0.00016 21.5 13.1 0.00016 21.5 13.1 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DUF2052 PF09747.9 EGG19336.1 - 1.2 9.3 18.4 0.15 12.2 11.9 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CLN3 PF02487.17 EGG19336.1 - 4.5 6.2 9.0 6.9 5.6 1.8 2.4 2 0 0 2 2 2 0 CLN3 protein Utp14 PF04615.13 EGG19336.1 - 5.5 5.4 26.6 0.04 12.5 11.4 2.1 2 0 0 2 2 2 0 Utp14 protein F-box-like PF12937.7 EGG19337.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like IF4E PF01652.18 EGG19338.1 - 3.9e-39 134.0 0.4 5.3e-39 133.6 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Arabinose_Isome PF02610.15 EGG19338.1 - 0.086 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 L-arabinose isomerase Connexin PF00029.19 EGG19339.1 - 0.22 11.3 4.0 0.23 11.2 4.0 1.0 1 0 0 1 1 1 0 Connexin Glutaredoxin PF00462.24 EGG19340.1 - 4.7e-18 65.2 0.2 6.7e-18 64.7 0.2 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 EGG19340.1 - 0.0057 17.1 1.4 0.047 14.1 1.4 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EGG19340.1 - 0.0078 16.2 0.5 0.017 15.2 0.5 1.6 1 1 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 EGG19340.1 - 0.019 15.4 0.7 0.06 13.8 0.7 1.9 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DHHC PF01529.20 EGG19341.1 - 5e-40 136.7 13.7 5e-40 136.7 13.7 2.9 3 0 0 3 3 3 1 DHHC palmitoyltransferase Coilin_N PF15862.5 EGG19341.1 - 0.00034 20.4 0.0 0.0005 19.9 0.0 1.3 1 0 0 1 1 1 1 Coilin N-terminus Peptidase_S49_N PF08496.10 EGG19341.1 - 0.0034 17.5 1.6 0.0034 17.5 1.6 1.7 2 0 0 2 2 2 1 Peptidase family S49 N-terminal Colicin_V PF02674.16 EGG19341.1 - 0.033 14.2 0.2 0.033 14.2 0.2 3.0 4 0 0 4 4 4 0 Colicin V production protein Zip PF02535.22 EGG19341.1 - 0.033 13.4 3.2 0.042 13.1 2.4 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter PspB PF06667.12 EGG19341.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.9 3 1 0 3 3 3 0 Phage shock protein B Transglut_core3 PF13471.6 EGG19341.1 - 0.16 11.8 0.2 0.59 10.0 0.1 1.8 2 0 0 2 2 2 0 Transglutaminase-like superfamily DUF2126 PF09899.9 EGG19341.1 - 0.4 8.7 2.3 0.56 8.2 2.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) EPL1 PF10513.9 EGG19341.1 - 0.66 10.3 12.4 1.1 9.6 12.4 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like eIF-4B PF06273.11 EGG19341.1 - 0.93 8.5 5.7 1.3 8.0 5.7 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF1272 PF06906.11 EGG19341.1 - 1.1 9.3 13.3 0.14 12.2 6.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) Presenilin PF01080.17 EGG19341.1 - 1.5 7.5 8.2 0.031 13.1 0.9 1.9 3 0 0 3 3 3 0 Presenilin ALMT PF11744.8 EGG19341.1 - 3.5 6.4 10.1 1.5 7.6 7.7 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter SDA1 PF05285.12 EGG19342.1 - 0.39 10.1 15.2 0.47 9.8 15.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EGG19342.1 - 0.56 8.4 10.9 0.62 8.3 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGG19342.1 - 0.57 8.3 17.7 0.66 8.1 17.7 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EGG19342.1 - 4 6.7 16.6 4.8 6.4 16.6 1.1 1 0 0 1 1 1 0 BUD22 zf_CCCH_4 PF18345.1 EGG19343.1 - 8.3e-25 86.1 53.9 3.8e-07 29.9 4.8 6.9 6 3 0 6 6 6 5 Zinc finger domain zf-CCCH PF00642.24 EGG19343.1 - 9.5e-22 76.4 48.3 1.3e-05 24.9 4.4 6.6 5 1 1 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGG19343.1 - 5.4e-13 49.6 53.4 0.0034 18.1 3.2 7.9 2 1 5 7 7 7 5 Torus domain zf-CCCH_2 PF14608.6 EGG19343.1 - 3.1e-11 43.3 60.7 0.0042 17.5 5.6 6.3 6 0 0 6 6 6 6 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EGG19343.1 - 3.1e-10 39.6 51.9 0.014 15.2 0.4 6.5 6 1 0 6 6 6 5 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EGG19343.1 - 1.9e-07 31.3 45.5 0.0063 16.7 1.1 6.8 6 1 1 7 7 7 5 Zinc-finger containing family eIF3_subunit PF08597.10 EGG19343.1 - 0.002 18.1 21.8 0.002 18.1 21.8 3.9 3 1 1 4 4 4 1 Translation initiation factor eIF3 subunit CLIP PF12032.8 EGG19343.1 - 1.7 9.0 15.7 8.5 6.7 0.2 5.9 6 0 0 6 6 6 0 Regulatory CLIP domain of proteinases DUF3844 PF12955.7 EGG19344.1 - 0.0031 17.6 1.5 0.013 15.6 1.5 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EAR PF07897.11 EGG19344.1 - 0.007 16.0 1.8 0.039 13.6 0.3 2.7 2 0 0 2 2 2 1 Ethylene-responsive binding factor-associated repression EGF_2 PF07974.13 EGG19344.1 - 0.0088 16.4 6.7 0.028 14.8 6.7 1.9 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 EGG19344.1 - 0.011 16.0 3.2 0.032 14.5 3.2 1.7 1 0 0 1 1 1 0 EB module DNMT1-RFD PF12047.8 EGG19344.1 - 0.09 12.8 2.6 0.099 12.7 0.9 1.9 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain EGF PF00008.27 EGG19344.1 - 2.3 8.6 6.4 7.1 7.0 6.4 1.8 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.24 EGG19345.1 - 3.2e-42 142.5 156.9 2.7e-12 46.6 1.1 14.0 13 1 0 13 13 13 10 IPT/TIG domain DNase_II PF03265.15 EGG19345.1 - 4.9e-26 91.8 0.0 1.4e-25 90.3 0.0 1.8 1 0 0 1 1 1 1 Deoxyribonuclease II ACI44 PF15270.6 EGG19345.1 - 0.19 12.0 2.7 0.72 10.1 2.7 2.1 1 0 0 1 1 1 0 Metallo-carboxypeptidase inhibitor TIG PF01833.24 EGG19346.1 - 1.3e-49 166.1 72.1 7.8e-11 41.9 3.6 9.7 9 1 0 9 9 9 8 IPT/TIG domain DNase_II PF03265.15 EGG19346.1 - 3.6e-39 134.9 0.0 1.2e-24 87.2 0.4 2.2 2 0 0 2 2 2 2 Deoxyribonuclease II TIG PF01833.24 EGG19347.1 - 9.9e-17 60.8 50.5 1.1e-07 31.9 6.7 9.2 7 1 1 8 8 8 5 IPT/TIG domain PsaD PF02531.16 EGG19347.1 - 0.033 13.7 0.0 0.19 11.3 0.0 2.2 3 0 0 3 3 3 0 PsaD DUF1966 PF09260.11 EGG19347.1 - 0.58 10.5 3.3 0.96 9.8 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1966) BTB_2 PF02214.22 EGG19348.1 - 1.6e-18 66.9 0.1 3.1e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 EGG19348.1 - 3e-17 63.2 0.2 5.9e-17 62.2 0.2 1.5 1 0 0 1 1 1 1 TLD DUF3860 PF12976.7 EGG19348.1 - 0.11 12.5 0.1 7.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) TLD PF07534.16 EGG19349.1 - 1.8e-16 60.6 4.5 3.5e-16 59.7 4.5 1.5 1 0 0 1 1 1 1 TLD BTB_2 PF02214.22 EGG19349.1 - 7.3e-15 55.1 0.0 1.6e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain TPR_MLP1_2 PF07926.12 EGG19349.1 - 0.024 14.7 1.8 0.035 14.1 1.8 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phg_2220_C PF09524.10 EGG19349.1 - 0.088 12.9 0.9 0.57 10.3 0.6 2.4 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Prefoldin PF02996.17 EGG19349.1 - 0.17 11.8 2.9 0.3 11.0 2.9 1.3 1 0 0 1 1 1 0 Prefoldin subunit Phage_GP20 PF06810.11 EGG19349.1 - 0.24 11.2 4.2 0.43 10.4 4.2 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 WD40_alt PF14077.6 EGG19349.1 - 0.88 9.5 4.3 0.93 9.4 2.6 1.9 1 1 0 1 1 1 0 Alternative WD40 repeat motif TIG PF01833.24 EGG19350.1 - 2.1e-57 191.1 125.2 1.5e-10 41.0 0.9 16.3 15 2 1 16 16 16 13 IPT/TIG domain DNase_II PF03265.15 EGG19350.1 - 4e-36 124.9 0.1 4.9e-23 81.9 0.9 2.5 2 0 0 2 2 2 2 Deoxyribonuclease II PsaD PF02531.16 EGG19350.1 - 0.11 12.0 0.0 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 PsaD DUF3844 PF12955.7 EGG19351.1 - 0.0017 18.5 2.7 0.0053 16.9 1.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) DNMT1-RFD PF12047.8 EGG19351.1 - 0.003 17.6 0.5 0.0062 16.6 0.5 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain EGF_2 PF07974.13 EGG19351.1 - 0.0037 17.6 7.4 0.0037 17.6 7.4 2.1 2 0 0 2 2 2 1 EGF-like domain LRR19-TM PF15176.6 EGG19351.1 - 0.0037 17.2 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain EGF_Tenascin PF18720.1 EGG19351.1 - 0.12 12.4 7.2 0.3 11.2 7.2 1.7 1 0 0 1 1 1 0 Tenascin EGF domain Sld5 PF05916.11 EGG19356.1 - 0.041 14.4 0.1 0.077 13.5 0.0 1.5 1 1 0 1 1 1 0 GINS complex protein PhoLip_ATPase_C PF16212.5 EGG19357.1 - 8.7e-67 225.5 27.0 8.7e-67 225.5 27.0 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGG19357.1 - 4.9e-20 71.0 10.4 6.3e-12 45.0 0.6 4.0 4 0 0 4 4 4 2 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGG19357.1 - 3.8e-13 50.2 0.1 5.3e-06 26.9 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG19357.1 - 1.5e-12 47.4 0.0 5.3e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGG19357.1 - 4e-11 42.8 1.1 6.7e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGG19357.1 - 0.0095 15.7 8.5 0.036 13.8 3.4 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase NapE PF06796.11 EGG19357.1 - 1.7 8.2 4.7 4.6 6.8 0.1 2.6 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE PseudoU_synth_2 PF00849.22 EGG19358.1 - 1.1e-13 51.5 0.0 1.1e-13 51.5 0.0 2.4 3 1 0 3 3 3 1 RNA pseudouridylate synthase S4 PF01479.25 EGG19358.1 - 8.1e-10 38.3 2.4 1.2e-09 37.7 0.1 2.5 3 0 0 3 3 3 1 S4 domain Pkinase_Tyr PF07714.17 EGG19360.1 - 3.1e-49 167.6 0.0 6e-49 166.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG19360.1 - 4.6e-48 163.9 0.7 1.1e-47 162.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain UBX PF00789.20 EGG19360.1 - 0.0014 18.8 0.0 0.0059 16.8 0.0 2.1 1 0 0 1 1 1 1 UBX domain Hpt PF01627.23 EGG19361.1 - 8.8e-09 35.5 0.1 1.6e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Hpt domain Maf_N PF08383.11 EGG19361.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Maf N-terminal region Lin-8 PF03353.15 EGG19361.1 - 0.052 13.1 13.7 0.069 12.7 13.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Utp14 PF04615.13 EGG19361.1 - 4.3 5.8 20.5 4.9 5.6 20.5 1.1 1 0 0 1 1 1 0 Utp14 protein SLC12 PF03522.15 EGG19361.1 - 9.6 5.1 15.1 15 4.5 15.1 1.4 1 0 0 1 1 1 0 Solute carrier family 12 SEC-C PF02810.15 EGG19362.1 - 1.3 9.0 12.0 0.63 10.0 3.7 2.4 2 0 0 2 2 2 0 SEC-C motif GvpD PF07088.11 EGG19363.1 - 0.0066 15.1 0.2 0.0067 15.1 0.2 1.0 1 0 0 1 1 1 1 GvpD gas vesicle protein RRM_1 PF00076.22 EGG19364.1 - 5.4e-15 55.0 0.3 2.1e-11 43.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG19364.1 - 0.0062 16.5 0.2 0.019 15.0 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EGG19364.1 - 0.0088 15.6 0.0 6.1 6.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GCP_C_terminal PF04130.13 EGG19365.1 - 8.4e-77 258.7 17.7 2.5e-76 257.1 13.6 2.9 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGG19365.1 - 2.2e-65 221.3 6.4 2.2e-65 221.3 6.4 3.0 3 2 0 3 3 3 1 Gamma tubulin complex component N-terminal CdhD PF03599.16 EGG19365.1 - 0.089 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit adh_short PF00106.25 EGG19366.1 - 5.5e-47 159.7 0.0 8.7e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG19366.1 - 6.5e-35 120.8 0.0 9.3e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG19366.1 - 1.2e-14 54.6 0.0 1.5e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG19366.1 - 7.9e-08 32.1 0.2 3e-07 30.2 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGG19366.1 - 9.5e-06 25.6 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGG19366.1 - 2.6e-05 23.5 0.0 3.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGG19366.1 - 0.00063 18.9 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGG19366.1 - 0.0011 18.4 0.2 0.004 16.6 0.2 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EGG19366.1 - 0.0013 19.0 0.1 0.0029 17.9 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EGG19366.1 - 0.0052 15.8 0.1 0.0099 14.9 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGG19366.1 - 0.0076 15.4 0.2 0.2 10.8 0.2 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EGG19367.1 - 3.4e-48 163.7 0.2 8.8e-48 162.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG19367.1 - 8.6e-36 123.7 0.0 1.5e-35 122.8 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG19367.1 - 2.5e-14 53.6 0.0 3.2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG19367.1 - 6.5e-08 32.3 0.1 2.4e-07 30.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGG19367.1 - 6.2e-06 26.2 0.0 8.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGG19367.1 - 1e-05 24.8 0.0 1.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGG19367.1 - 4.7e-05 22.6 0.0 9e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGG19367.1 - 0.00019 21.0 0.1 0.0007 19.1 0.1 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EGG19367.1 - 0.0018 18.5 0.0 0.0046 17.2 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EGG19367.1 - 0.003 16.6 0.1 0.0047 16.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGG19367.1 - 0.013 14.7 0.1 0.26 10.4 0.1 2.3 1 1 0 1 1 1 0 Male sterility protein DUF1776 PF08643.10 EGG19367.1 - 0.036 13.4 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TrkA_N PF02254.18 EGG19367.1 - 0.12 12.7 0.3 0.47 10.7 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain Cofilin_ADF PF00241.20 EGG19368.1 - 1.6e-37 128.0 0.1 1.2e-21 76.8 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Autoind_bind PF03472.15 EGG19368.1 - 0.17 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Autoinducer binding domain BolA PF01722.18 EGG19369.1 - 2.9e-12 46.7 0.0 8e-12 45.3 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein INTS2 PF14750.6 EGG19370.1 - 1.4e-97 327.5 34.6 9.7e-86 288.3 29.1 3.2 2 1 0 2 2 2 2 Integrator complex subunit 2 Herpes_LMP1 PF05297.11 EGG19370.1 - 0.12 11.5 3.7 0.24 10.6 3.7 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) MOZART1 PF12554.8 EGG19370.1 - 0.15 11.9 3.2 0.8 9.5 0.1 3.3 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF4611 PF15387.6 EGG19370.1 - 0.33 11.2 3.3 0.85 9.9 1.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 EGG19370.1 - 0.37 11.2 4.0 1.2 9.5 4.0 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CBFD_NFYB_HMF PF00808.23 EGG19371.1 - 2.7e-15 56.4 1.1 5e-15 55.5 1.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGG19371.1 - 1.3e-08 35.3 0.3 1.3e-08 35.3 0.3 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EGG19371.1 - 0.022 14.9 0.2 0.06 13.5 0.1 1.8 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) CENP-X PF09415.10 EGG19371.1 - 0.18 12.1 0.1 0.35 11.2 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Dicty_spore_N PF04562.12 EGG19373.1 - 6.7e-13 49.3 10.4 6.7e-13 49.3 10.4 3.8 2 1 2 4 4 4 1 Dictyostelium spore coat protein, N terminus Sigma_reg_C PF13791.6 EGG19373.1 - 0.37 11.0 3.4 0.67 10.2 3.4 1.4 1 0 0 1 1 1 0 Sigma factor regulator C-terminal PAP_central PF04928.17 EGG19374.1 - 1e-110 368.6 0.0 1.4e-110 368.1 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EGG19374.1 - 7.5e-29 100.5 1.7 7.8e-19 67.9 0.0 2.8 2 1 1 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EGG19374.1 - 1.4e-07 31.7 0.0 3.3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 EGG19374.1 - 0.011 15.5 0.1 0.035 13.9 0.1 1.8 1 1 0 1 1 1 0 Nrap protein PAP/OAS-like domain CYYR1 PF10873.8 EGG19374.1 - 0.16 12.4 6.8 0.53 10.7 6.8 1.8 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 NPR3 PF03666.13 EGG19374.1 - 1.1 7.9 4.5 2 7.1 4.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ExbD PF02472.16 EGG19374.1 - 5.8 7.1 9.4 0.087 13.0 0.9 2.2 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR ColG_sub PF18496.1 EGG19375.1 - 0.035 14.2 0.2 0.13 12.4 0.2 1.9 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain tRNA-synt_1 PF00133.22 EGG19377.1 - 3.1e-202 673.1 0.1 3.1e-202 673.1 0.1 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGG19377.1 - 7.8e-37 126.6 0.3 7.8e-37 126.6 0.3 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGG19377.1 - 3.6e-15 55.6 0.2 2e-07 30.1 0.0 4.2 3 1 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGG19377.1 - 1.5e-05 24.6 0.0 1.5e-05 24.6 0.0 3.5 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EGG19377.1 - 0.0071 15.7 0.0 0.0071 15.7 0.0 3.0 4 0 0 4 4 4 1 tRNA synthetases class I (C) catalytic domain Tim54 PF11711.8 EGG19377.1 - 1.1 8.0 11.3 1.7 7.3 11.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.10 EGG19377.1 - 4 7.7 20.0 11 6.4 20.0 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ras PF00071.22 EGG19380.1 - 2.2e-44 150.9 0.1 2.6e-44 150.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG19380.1 - 1.3e-28 99.6 0.1 1.8e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG19380.1 - 6.3e-10 38.8 0.1 7.3e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG19380.1 - 3.6e-06 26.5 0.0 4.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EGG19380.1 - 0.00055 19.7 0.1 0.0062 16.3 0.0 2.2 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EGG19380.1 - 0.00065 19.3 0.4 0.069 12.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG19380.1 - 0.0025 17.9 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 EGG19380.1 - 0.0033 17.0 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 EGG19380.1 - 0.0033 16.8 0.1 0.045 13.2 0.1 2.2 1 1 1 2 2 2 1 Bacterial TniB protein ATP_bind_1 PF03029.17 EGG19380.1 - 0.0062 16.3 0.0 0.77 9.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 EGG19380.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGG19380.1 - 0.028 14.3 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 EGG19380.1 - 0.056 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EGG19380.1 - 0.059 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EGG19380.1 - 0.066 12.9 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EGG19380.1 - 0.071 12.3 0.0 7.4 5.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit SRP54 PF00448.22 EGG19380.1 - 0.086 12.5 0.0 5.1 6.7 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA PF00004.29 EGG19380.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGG19380.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 EGG19380.1 - 0.25 10.1 0.1 0.4 9.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain P3A PF08727.11 EGG19380.1 - 6.5 6.2 5.9 1.2 8.5 0.0 2.5 2 1 1 3 3 3 0 Poliovirus 3A protein like Dynein_light PF01221.18 EGG19381.1 - 2.8e-09 37.2 3.0 3e-09 37.1 3.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 MMgT PF10270.9 EGG19382.1 - 2.4e-12 47.1 0.6 2.8e-12 46.9 0.6 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter SieB PF14163.6 EGG19382.1 - 0.22 11.0 2.0 9.8 5.7 0.1 2.0 2 0 0 2 2 2 0 Super-infection exclusion protein B ADK PF00406.22 EGG19383.1 - 7.7e-58 194.9 0.0 1.1e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGG19383.1 - 3e-24 86.0 0.0 5.6e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EGG19383.1 - 2.5e-16 59.4 0.0 5.8e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 EGG19383.1 - 0.0011 19.2 0.0 1.1 9.5 0.0 2.3 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 EGG19383.1 - 0.0048 17.1 0.0 0.0098 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGG19383.1 - 0.0068 16.2 0.0 0.015 15.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGG19383.1 - 0.071 13.7 0.0 0.18 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGG19383.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Otopetrin PF03189.13 EGG19384.1 - 1.8e-07 30.4 1.4 0.0073 15.2 0.0 4.0 3 1 0 3 3 3 1 Otopetrin Lactamase_B PF00753.27 EGG19385.1 - 2e-10 41.0 1.3 3.5e-10 40.2 1.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 EGG19385.1 - 6.9e-09 35.6 0.0 1.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 EGG19385.1 - 1.9e-08 34.0 0.6 3.3e-08 33.3 0.6 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF4523 PF15023.6 EGG19385.1 - 0.094 12.5 0.7 0.18 11.6 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) DUF3430 PF11912.8 EGG19386.1 - 2.6e-22 79.9 68.1 1.1e-13 51.7 28.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGG19386.1 - 0.00011 22.4 11.3 0.22 11.8 1.8 4.8 3 1 1 4 4 4 3 Protein of unknown function (DUF3586) EF-hand_1 PF00036.32 EGG19387.1 - 0.083 12.5 1.9 0.35 10.5 1.9 2.2 1 0 0 1 1 1 0 EF hand SUIM_assoc PF16619.5 EGG19388.1 - 0.036 14.1 3.5 0.072 13.2 3.5 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 F-box PF00646.33 EGG19388.1 - 0.21 11.5 2.0 0.25 11.3 0.2 2.1 2 0 0 2 2 2 0 F-box domain Frizzled PF01534.17 EGG19389.1 - 3.8e-12 45.9 16.4 6.2e-12 45.2 16.4 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 EGG19389.1 - 1.2e-06 28.0 11.7 1.2e-06 28.0 11.7 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) MscS_TM PF12794.7 EGG19389.1 - 0.012 14.5 0.4 0.028 13.3 0.2 1.7 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4834 PF16118.5 EGG19389.1 - 0.072 14.1 7.9 0.088 13.8 4.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2975 PF11188.8 EGG19389.1 - 0.31 10.9 9.7 1.7 8.6 1.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) Apis_Csd PF11671.8 EGG19389.1 - 1.4 8.9 7.9 2.9 7.9 7.9 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein COesterase PF00135.28 EGG19390.1 - 2.6e-14 53.0 0.1 7.5e-14 51.5 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG19390.1 - 1.3e-12 48.1 0.1 1.9e-12 47.5 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG19390.1 - 3.1e-07 30.1 0.1 2.9e-06 26.9 0.1 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Lipase PF00151.19 EGG19390.1 - 0.00092 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipase Say1_Mug180 PF10340.9 EGG19390.1 - 0.0011 17.9 0.3 0.0025 16.7 0.2 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EGG19390.1 - 0.0015 17.9 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 EGG19390.1 - 0.0028 16.2 0.1 0.0061 15.1 0.0 1.5 1 1 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EGG19390.1 - 0.0038 16.2 0.0 0.0052 15.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.9 EGG19390.1 - 0.0039 16.7 0.0 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 EGG19390.1 - 0.0077 16.9 0.0 0.012 16.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EGG19390.1 - 0.029 14.2 0.1 6.7 6.5 0.1 2.1 1 1 0 2 2 2 0 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 EGG19390.1 - 0.06 13.1 0.0 2 8.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 EGG19390.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Phage_Mu_Gp45 PF06890.12 EGG19391.1 - 0.15 11.8 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein PP2C PF00481.21 EGG19392.1 - 5.8e-55 186.7 0.0 5.8e-55 186.7 0.0 2.4 3 0 0 3 3 3 1 Protein phosphatase 2C LRR_8 PF13855.6 EGG19392.1 - 3.5e-41 138.8 44.9 5e-08 32.6 0.3 9.2 7 2 2 9 9 9 6 Leucine rich repeat LRR_4 PF12799.7 EGG19392.1 - 2.5e-31 107.2 53.1 2.7e-06 27.6 1.5 13.0 8 5 6 14 14 13 11 Leucine Rich repeats (2 copies) PP2C_2 PF13672.6 EGG19392.1 - 0.00042 20.0 0.0 0.001 18.7 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.6 EGG19392.1 - 0.00061 19.3 15.1 0.75 9.3 1.7 6.0 3 2 3 6 6 6 2 Leucine-rich repeat MFS_1 PF07690.16 EGG19392.1 - 0.011 14.7 24.2 0.054 12.4 12.8 2.6 1 1 1 2 2 2 0 Major Facilitator Superfamily CitMHS PF03600.16 EGG19392.1 - 0.019 14.2 3.0 0.27 10.4 0.2 2.2 1 1 1 2 2 2 0 Citrate transporter LRR_6 PF13516.6 EGG19392.1 - 1.7 8.9 46.1 1.3 9.2 0.2 11.0 13 0 0 13 13 13 0 Leucine Rich repeat DUF1774 PF08611.10 EGG19392.1 - 4.6 7.6 6.8 2.2 8.6 3.3 2.4 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) Endosulfine PF04667.17 EGG19393.1 - 1.3e-12 47.7 0.8 1.4e-12 47.6 0.8 1.1 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Proteasome PF00227.26 EGG19394.1 - 4.9e-57 192.5 1.0 7.1e-57 192.0 1.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGG19394.1 - 4.3e-14 51.9 0.1 8e-14 51.0 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Peptidase_C71 PF12386.8 EGG19394.1 - 0.078 12.6 1.1 0.13 11.9 1.1 1.3 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei HORMA PF02301.18 EGG19396.1 - 8.9e-08 32.0 9.4 8.9e-08 32.0 9.4 3.2 1 1 2 4 4 4 1 HORMA domain Acyltransferase PF01553.21 EGG19397.1 - 1.8e-22 79.4 0.0 2.7e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EGG19397.1 - 1.7e-13 50.5 0.0 3.9e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus 7tm_7 PF08395.12 EGG19397.1 - 0.015 14.5 5.5 0.039 13.2 0.9 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF1129 PF06570.11 EGG19397.1 - 0.18 11.3 5.4 0.15 11.6 2.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) WD40 PF00400.32 EGG19398.1 - 6.5e-25 86.9 14.9 5.1e-05 24.0 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG19398.1 - 4.3e-16 59.0 0.0 0.0078 16.5 0.1 5.5 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG19398.1 - 5.6e-05 22.3 0.4 0.33 9.9 0.3 3.1 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4805 PF16063.5 EGG19398.1 - 0.0039 16.6 8.8 0.0039 16.6 8.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4805) Proteasome_A_N PF10584.9 EGG19398.1 - 0.016 14.8 0.8 29 4.5 0.1 4.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 EGG19398.1 - 0.33 11.0 5.9 13 5.9 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Dapper PF15268.6 EGG19398.1 - 0.37 9.6 24.8 0.6 8.9 9.8 2.1 2 0 0 2 2 2 0 Dapper Prothymosin PF03247.14 EGG19398.1 - 0.42 11.1 39.5 2.4 8.6 17.3 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family TLP-20 PF06088.11 EGG19398.1 - 1.2 9.0 23.2 1.2 9.0 6.2 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SID-1_RNA_chan PF13965.6 EGG19398.1 - 1.5 7.2 12.8 0.59 8.5 2.1 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DDHD PF02862.17 EGG19398.1 - 2.1 8.5 20.6 0.52 10.4 2.3 2.3 2 0 0 2 2 2 0 DDHD domain CAC1F_C PF16885.5 EGG19398.1 - 4.4 6.9 17.8 3.9 7.1 3.9 2.2 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term Ank_2 PF12796.7 EGG19399.1 - 5.7e-14 52.5 6.8 2.9e-06 27.8 0.0 4.7 4 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19399.1 - 1.3e-11 44.8 0.1 0.012 16.2 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19399.1 - 0.00021 21.5 0.5 14 6.1 0.0 6.3 5 2 2 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19399.1 - 0.00044 20.5 4.1 25 5.9 0.0 7.7 9 0 0 9 9 9 1 Ankyrin repeat Pneumo_att_G PF05539.11 EGG19399.1 - 0.032 13.8 2.2 0.056 13.0 2.2 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF3439 PF11921.8 EGG19399.1 - 0.28 11.2 3.5 0.61 10.1 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) BLUF PF04940.12 EGG19400.1 - 0.089 12.9 0.4 0.23 11.6 0.1 1.9 2 0 0 2 2 2 0 Sensors of blue-light using FAD RII_binding_1 PF10522.9 EGG19400.1 - 0.99 9.8 3.6 1.5 9.3 0.4 2.9 2 1 0 2 2 2 0 RII binding domain Dicty_spore_N PF04562.12 EGG19402.1 - 1.1e-49 167.8 50.2 1.7e-26 93.1 22.5 5.6 4 2 2 6 6 6 2 Dictyostelium spore coat protein, N terminus FOLN PF09289.10 EGG19402.1 - 0.017 15.3 3.3 0.017 15.3 3.3 5.6 5 0 0 5 5 5 0 Follistatin/Osteonectin-like EGF domain Nipped-B_C PF12830.7 EGG19403.1 - 7.8e-28 97.7 2.4 5.3e-20 72.2 0.1 5.8 5 1 1 6 6 6 2 Sister chromatid cohesion C-terminus HEAT_2 PF13646.6 EGG19403.1 - 6.1e-07 29.7 0.0 0.016 15.6 0.0 3.5 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 EGG19403.1 - 1.4e-06 28.4 0.1 1.4e-06 28.4 0.1 8.0 5 2 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 EGG19403.1 - 3.8e-06 27.1 0.6 3.8e-06 27.1 0.6 3.4 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion PHD PF00628.29 EGG19403.1 - 9.3e-05 22.2 11.7 0.00023 21.0 11.7 1.7 1 0 0 1 1 1 1 PHD-finger HEAT PF02985.22 EGG19403.1 - 0.00014 21.8 0.0 14 6.2 0.0 6.0 5 0 0 5 5 5 1 HEAT repeat YL1 PF05764.13 EGG19403.1 - 0.00047 20.4 10.5 0.00047 20.4 10.5 4.1 4 0 0 4 4 4 1 YL1 nuclear protein RTP1_C1 PF10363.9 EGG19403.1 - 0.037 14.2 5.8 2.8 8.2 0.0 4.5 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 BssS PF13991.6 EGG19403.1 - 0.059 13.4 1.1 1.3 9.1 0.3 2.9 2 0 0 2 2 2 0 BssS protein family FYVE_2 PF02318.16 EGG19403.1 - 0.63 10.3 12.2 0.029 14.6 3.5 3.0 2 0 0 2 2 2 0 FYVE-type zinc finger PHD_2 PF13831.6 EGG19403.1 - 4 7.1 6.1 8.1 6.1 6.1 1.6 1 0 0 1 1 1 0 PHD-finger Pyr_redox_2 PF07992.14 EGG19404.1 - 4.1e-47 160.8 0.0 5.2e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG19404.1 - 7.1e-09 36.1 0.0 4.6e-07 30.3 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG19404.1 - 0.02 15.1 0.0 1.3 9.3 0.0 3.0 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain PCB_OB PF17092.5 EGG19404.1 - 0.033 15.0 0.0 0.066 14.0 0.0 1.5 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain GMC_oxred_C PF05199.13 EGG19404.1 - 0.045 14.3 0.0 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Macoilin PF09726.9 EGG19404.1 - 9.8 4.6 10.3 15 3.9 10.3 1.2 1 0 0 1 1 1 0 Macoilin family RabGAP-TBC PF00566.18 EGG19405.1 - 6.3e-38 130.6 7.0 7.8e-38 130.3 7.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LAGLIDADG_1 PF00961.19 EGG19405.1 - 0.52 11.3 6.9 1.3 10.1 6.9 1.6 1 0 0 1 1 1 0 LAGLIDADG endonuclease KLRAQ PF10205.9 EGG19407.1 - 3.1e-26 91.5 10.5 3.1e-26 91.5 10.5 6.6 5 2 3 8 8 8 1 Predicted coiled-coil domain-containing protein TTKRSYEDQ PF10212.9 EGG19407.1 - 5.6e-09 35.5 11.4 5.6e-09 35.5 11.4 3.6 3 1 0 3 3 3 1 Predicted coiled-coil domain-containing protein DUF1515 PF07439.11 EGG19407.1 - 0.0015 18.5 0.5 0.0015 18.5 0.5 4.5 6 0 0 6 6 6 1 Protein of unknown function (DUF1515) PIN_8 PF18476.1 EGG19407.1 - 0.0085 16.0 5.3 0.0085 16.0 5.3 6.0 3 2 1 6 6 6 1 PIN like domain zinc_ribbon_5 PF13719.6 EGG19407.1 - 0.021 14.6 0.9 0.052 13.3 0.9 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Mito_carr PF00153.27 EGG19408.1 - 1.1e-45 153.5 5.5 3.3e-21 75.0 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGG19408.1 - 0.0043 16.2 3.9 0.076 12.2 0.0 3.0 1 1 1 3 3 3 1 Gammaproteobacterial serine protease RE_HpaII PF09561.10 EGG19408.1 - 0.046 13.1 0.1 0.089 12.2 0.1 1.4 1 0 0 1 1 1 0 HpaII restriction endonuclease UPF0154 PF03672.13 EGG19408.1 - 0.51 10.4 3.7 0.43 10.6 0.3 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) SNARE_assoc PF09335.11 EGG19409.1 - 1.7e-16 60.8 0.9 1.7e-16 60.8 0.9 1.8 1 1 1 2 2 2 1 SNARE associated Golgi protein CAC1F_C PF16885.5 EGG19409.1 - 0.00028 20.7 0.2 0.00028 20.7 0.2 1.1 1 0 0 1 1 1 1 Voltage-gated calcium channel subunit alpha, C-term Orf78 PF06024.12 EGG19409.1 - 0.0092 16.3 2.0 0.0092 16.3 2.0 3.5 1 1 2 3 3 3 1 Orf78 (ac78) LAP1C PF05609.12 EGG19409.1 - 0.043 12.9 16.6 0.058 12.5 16.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) AvrRpt-cleavage PF05627.11 EGG19409.1 - 0.13 11.6 0.9 0.39 10.1 0.9 1.8 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr WD40 PF00400.32 EGG19410.1 - 1.1e-24 86.2 17.7 2.4e-06 28.2 0.5 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat HEAT PF02985.22 EGG19410.1 - 1.2e-16 59.4 0.2 0.011 15.9 0.0 9.2 9 0 0 9 9 8 4 HEAT repeat ANAPC4_WD40 PF12894.7 EGG19410.1 - 2.4e-16 59.8 0.4 6.6e-06 26.3 0.0 5.0 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain HEAT_EZ PF13513.6 EGG19410.1 - 7.9e-14 51.8 0.5 0.46 11.0 0.0 9.6 8 1 2 10 10 10 4 HEAT-like repeat HEAT_2 PF13646.6 EGG19410.1 - 1.3e-13 51.1 0.0 0.0075 16.6 0.0 6.3 4 1 2 6 6 6 2 HEAT repeats Cnd1 PF12717.7 EGG19410.1 - 1.4e-10 41.5 2.0 1.4e-05 25.2 0.0 5.6 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Importin_rep_4 PF18808.1 EGG19410.1 - 5.3e-09 36.3 7.0 6.5e-09 36.0 0.3 3.7 4 0 0 4 4 3 1 Importin repeat Vac14_Fab1_bd PF12755.7 EGG19410.1 - 5.9e-08 33.2 0.0 0.0017 18.9 0.0 6.0 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Ge1_WD40 PF16529.5 EGG19410.1 - 2.6e-07 29.9 0.4 0.0025 16.8 0.0 2.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CLASP_N PF12348.8 EGG19410.1 - 3.4e-05 23.5 0.6 6 6.4 0.0 5.5 5 1 1 6 6 6 1 CLASP N terminal RIX1 PF08167.12 EGG19410.1 - 4e-05 23.4 0.3 0.0015 18.4 0.0 3.2 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis WD40_like PF17005.5 EGG19410.1 - 4.5e-05 22.9 0.4 0.088 12.1 0.0 3.2 3 0 0 3 3 3 2 WD40-like domain B56 PF01603.20 EGG19410.1 - 0.0019 17.3 0.0 0.016 14.2 0.0 2.5 2 0 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) OSCP PF00213.18 EGG19410.1 - 0.012 15.8 0.1 0.75 9.9 0.0 3.4 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit ERAP1_C PF11838.8 EGG19410.1 - 0.017 14.7 0.1 8 5.9 0.0 3.1 3 0 0 3 3 3 0 ERAP1-like C-terminal domain Sigma_reg_C PF13791.6 EGG19410.1 - 0.019 15.2 0.3 0.053 13.7 0.3 1.8 1 0 0 1 1 1 0 Sigma factor regulator C-terminal ParcG PF10274.9 EGG19410.1 - 0.028 14.6 0.1 0.51 10.4 0.0 3.2 4 0 0 4 4 3 0 Parkin co-regulated protein Peptidase_M22 PF00814.25 EGG19411.1 - 1.3e-78 264.5 0.0 9.1e-68 228.9 0.1 2.1 2 0 0 2 2 2 2 Glycoprotease family Kinetochor_Ybp2 PF08568.10 EGG19411.1 - 0.0048 15.4 2.7 0.0072 14.9 2.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin FGGY_C PF02782.16 EGG19411.1 - 0.022 14.5 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Dodecin PF07311.12 EGG19411.1 - 0.04 14.2 0.3 0.12 12.6 0.1 1.9 2 0 0 2 2 1 0 Dodecin DUF4985 PF16373.5 EGG19411.1 - 0.094 13.2 1.3 8.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function SMYLE_N PF18615.1 EGG19411.1 - 0.27 10.8 3.3 0.57 9.7 3.3 1.5 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Inhibitor_I71 PF12628.7 EGG19411.1 - 0.4 10.5 9.1 4.1 7.2 1.1 2.5 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor MEIOC PF15189.6 EGG19411.1 - 1 8.9 4.9 0.32 10.6 0.5 2.1 1 1 1 2 2 2 0 Meiosis-specific coiled-coil domain-containing protein MEIOC NPR1_interact PF15699.5 EGG19411.1 - 1.6 9.4 12.0 2.7 8.7 1.2 2.4 2 0 0 2 2 2 0 NPR1 interacting Tau95_N PF17682.1 EGG19411.1 - 1.8 8.8 7.4 0.18 12.0 0.3 2.5 3 0 0 3 3 3 0 Tau95 Triple barrel domain Presenilin PF01080.17 EGG19411.1 - 3 6.5 8.1 4.7 5.9 8.1 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 EGG19411.1 - 3.5 8.6 10.4 3.9 8.5 0.8 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) Ras PF00071.22 EGG19412.1 - 1e-49 168.2 0.0 1.3e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG19412.1 - 4.3e-31 107.6 0.0 6.7e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG19412.1 - 2.3e-12 46.7 0.0 2.9e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG19412.1 - 4.5e-05 23.5 0.0 7.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGG19412.1 - 0.00017 20.9 1.2 0.46 9.6 0.0 3.0 2 1 1 3 3 3 2 G-protein alpha subunit GTP_EFTU PF00009.27 EGG19412.1 - 0.00034 20.2 0.0 0.0013 18.3 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 EGG19412.1 - 0.00057 20.2 0.1 0.0081 16.5 0.1 2.2 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 EGG19412.1 - 0.0014 18.0 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGG19412.1 - 0.016 15.1 0.0 0.96 9.3 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EGG19412.1 - 0.05 13.3 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGG19412.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EGG19412.1 - 0.11 12.8 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.12 EGG19412.1 - 0.12 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.6 EGG19412.1 - 0.13 12.4 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain ArgoMid PF16487.5 EGG19412.1 - 0.13 12.5 0.1 0.32 11.3 0.1 1.6 1 1 0 1 1 1 0 Mid domain of argonaute NTPase_1 PF03266.15 EGG19412.1 - 0.15 12.0 0.2 0.23 11.4 0.2 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 EGG19412.1 - 0.15 12.0 0.1 0.24 11.3 0.1 1.2 1 0 0 1 1 1 0 NACHT domain Med14 PF08638.11 EGG19413.1 - 6.2e-58 195.4 0.2 6.2e-58 195.4 0.2 2.0 2 0 0 2 2 2 1 Mediator complex subunit MED14 Activator-TraM PF11657.8 EGG19413.1 - 0.059 13.2 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Transcriptional activator TraM WYL_2 PF10902.8 EGG19413.1 - 0.71 10.3 3.7 1.7 9.1 0.0 3.3 4 0 0 4 4 4 0 WYL_2, Sm-like SH3 beta-barrel fold NMD3 PF04981.13 EGG19414.1 - 1.1e-78 264.0 7.6 1.1e-78 264.0 7.6 1.7 2 0 0 2 2 2 1 NMD3 family Cwf_Cwc_15 PF04889.12 EGG19414.1 - 0.0069 16.1 16.2 0.012 15.4 16.2 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF1289 PF06945.13 EGG19414.1 - 0.74 9.7 5.3 4.2 7.3 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) CNDH2_C PF16858.5 EGG19415.1 - 1.5e-43 149.8 0.0 1.5e-43 149.8 0.0 4.1 3 1 1 4 4 4 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 EGG19415.1 - 1.3e-38 131.6 0.7 1.3e-38 131.6 0.7 3.7 5 0 0 5 5 5 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Rad21_Rec8_N PF04825.13 EGG19415.1 - 0.066 13.4 0.1 0.23 11.6 0.1 2.0 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein OTU PF02338.19 EGG19416.1 - 2.2e-11 44.3 0.6 6.6e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease Actin PF00022.19 EGG19417.1 - 6.3e-119 397.2 0.0 1.5e-118 395.9 0.0 1.6 1 1 0 1 1 1 1 Actin Ist1 PF03398.14 EGG19417.1 - 2.1e-41 141.6 0.8 3.4e-41 140.9 0.8 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Filamin PF00630.19 EGG19417.1 - 2.3e-41 140.8 2.7 9.6e-21 74.5 0.5 3.0 2 0 0 2 2 2 2 Filamin/ABP280 repeat Cation_ATPase_C PF00689.21 EGG19417.1 - 1.1e-37 129.6 8.6 1.1e-37 129.6 8.6 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGG19417.1 - 8.8e-35 119.9 4.7 1.3e-34 119.3 0.0 3.2 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGG19417.1 - 1e-13 52.1 5.0 9.5e-13 48.9 5.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGG19417.1 - 1.7e-07 31.3 3.0 6.5e-05 22.8 1.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG19417.1 - 1.9e-07 31.1 0.0 6.6e-06 26.1 0.0 2.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Invasin_D3 PF09134.10 EGG19417.1 - 7.4e-06 26.2 1.6 0.027 14.8 0.0 3.1 3 0 0 3 3 3 2 Invasin, domain 3 Phage_holin_2_3 PF16080.5 EGG19417.1 - 0.079 12.7 0.5 0.24 11.2 0.5 1.8 1 0 0 1 1 1 0 Bacteriophage holin family HP1 Neurexophilin PF06312.12 EGG19417.1 - 0.45 9.9 2.9 12 5.3 0.1 2.4 1 1 0 2 2 2 0 Neurexophilin DUF5011 PF16403.5 EGG19417.1 - 0.71 10.0 4.3 0.67 10.1 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) DEAD PF00270.29 EGG19418.1 - 1.4e-47 161.8 0.7 3.4e-47 160.5 0.7 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG19418.1 - 8.3e-22 77.6 0.1 6.9e-21 74.7 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGG19418.1 - 3.2e-15 56.1 0.1 1.8e-14 53.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 EGG19418.1 - 0.0028 17.9 0.5 0.22 11.8 0.0 3.6 4 0 0 4 4 4 1 AAA domain Transket_pyr PF02779.24 EGG19419.1 - 1.8e-44 151.5 0.0 3.3e-44 150.7 0.0 1.4 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGG19419.1 - 2e-33 114.9 0.0 3.1e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain EF-hand_6 PF13405.6 EGG19421.1 - 0.00012 21.7 0.3 0.00074 19.2 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EGG19421.1 - 0.00042 19.7 0.5 0.0012 18.2 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EGG19421.1 - 0.014 14.9 0.1 0.046 13.2 0.0 1.9 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 EGG19421.1 - 0.062 13.8 0.1 0.062 13.8 0.1 3.0 3 1 0 3 3 3 0 EF-hand domain pair Presenilin PF01080.17 EGG19421.1 - 0.41 9.4 2.2 0.55 8.9 2.2 1.3 1 0 0 1 1 1 0 Presenilin EIIBC-GUT_N PF03612.14 EGG19421.1 - 4.6 6.9 5.9 29 4.3 3.7 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Cytomega_UL84 PF06284.11 EGG19421.1 - 6.1 5.2 8.0 8.7 4.7 8.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Tctex-1 PF03645.13 EGG19422.1 - 1.8e-10 41.0 0.9 2.1e-10 40.7 0.9 1.1 1 0 0 1 1 1 1 Tctex-1 family RE_TdeIII PF09520.10 EGG19422.1 - 0.019 14.7 0.2 0.021 14.5 0.2 1.0 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII NOT2_3_5 PF04153.18 EGG19423.1 - 6.8e-28 97.4 0.8 6.8e-28 97.4 0.8 2.8 3 0 0 3 3 1 1 NOT2 / NOT3 / NOT5 family PEHE PF15275.6 EGG19423.1 - 0.0022 18.6 10.8 0.0022 18.6 10.8 2.7 2 1 0 2 2 1 1 PEHE domain Spt20 PF12090.8 EGG19423.1 - 0.0022 17.6 38.7 0.0022 17.6 38.7 2.5 3 0 0 3 3 2 1 Spt20 family Connexin PF00029.19 EGG19423.1 - 0.0061 16.4 2.6 0.011 15.5 2.6 1.4 1 0 0 1 1 1 1 Connexin RNA_pol_Rpc4 PF05132.14 EGG19423.1 - 0.027 14.9 14.7 0.043 14.2 5.3 2.5 2 1 0 2 2 2 0 RNA polymerase III RPC4 eIF-3_zeta PF05091.12 EGG19423.1 - 0.04 12.9 15.7 0.06 12.3 15.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MCM_bind PF09739.9 EGG19423.1 - 0.25 9.7 15.5 0.45 8.9 15.5 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SID-1_RNA_chan PF13965.6 EGG19423.1 - 0.27 9.6 1.9 0.46 8.8 1.9 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EOS1 PF12326.8 EGG19423.1 - 0.37 10.7 7.0 0.27 11.2 2.1 2.1 2 0 0 2 2 2 0 N-glycosylation protein EIF4E-T PF10477.9 EGG19423.1 - 0.38 9.5 30.5 0.14 11.0 22.2 2.0 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E PcfK PF14058.6 EGG19423.1 - 0.4 11.0 14.7 0.81 10.0 14.7 1.4 1 0 0 1 1 1 0 PcfK-like protein Afi1 PF07792.12 EGG19423.1 - 0.44 11.0 14.6 0.51 10.8 10.7 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TFIIA PF03153.13 EGG19423.1 - 0.67 9.9 55.8 0.16 11.9 37.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 EGG19423.1 - 0.83 9.7 23.2 0.023 14.7 15.2 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Peroxin-13_N PF04088.13 EGG19423.1 - 0.94 9.8 6.4 2.6 8.3 6.4 1.7 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF4638 PF15472.6 EGG19423.1 - 1.3 8.7 9.4 2.3 7.9 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) SpoIIP PF07454.11 EGG19423.1 - 1.7 8.1 17.9 0.071 12.6 11.9 1.6 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) EMC3_TMCO1 PF01956.16 EGG19423.1 - 2 8.1 9.0 3.5 7.3 9.0 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like NARP1 PF12569.8 EGG19423.1 - 2.2 7.1 11.5 3.7 6.3 11.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDRGK PF09756.9 EGG19423.1 - 2.3 7.8 18.0 2 7.9 16.9 1.4 2 0 0 2 2 1 0 DDRGK domain Peptidase_S49_N PF08496.10 EGG19423.1 - 2.9 7.9 10.0 6.1 6.9 10.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Neur_chan_memb PF02932.16 EGG19423.1 - 3.1 7.8 15.0 0.43 10.6 8.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Paf1 PF03985.13 EGG19423.1 - 3.7 6.4 18.0 6 5.8 18.0 1.2 1 0 0 1 1 1 0 Paf1 CPSF100_C PF13299.6 EGG19423.1 - 4.8 7.3 18.5 1.3 9.2 13.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4175 PF13779.6 EGG19423.1 - 5 4.9 35.2 7.9 4.3 35.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Serinc PF03348.15 EGG19423.1 - 5 5.9 10.9 0.43 9.5 4.9 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF4770 PF15994.5 EGG19423.1 - 5.1 7.3 16.7 9.9 6.4 16.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FAM60A PF15396.6 EGG19423.1 - 5.1 7.0 12.3 1.3 9.0 7.2 2.1 2 0 0 2 2 2 0 Protein Family FAM60A MPM1 PF17234.2 EGG19423.1 - 7.9 6.7 19.6 0.97 9.7 14.1 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Tim54 PF11711.8 EGG19423.1 - 8.2 5.1 17.7 0.42 9.3 12.0 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 BRF1 PF07741.13 EGG19423.1 - 8.7 6.8 14.2 0.37 11.2 8.1 1.8 2 0 0 2 2 1 0 Brf1-like TBP-binding domain Mon2_C PF16206.5 EGG19426.1 - 4.1e-69 233.6 6.8 2e-46 158.6 0.6 3.1 2 1 0 2 2 2 2 C-terminal region of Mon2 protein DCB PF16213.5 EGG19426.1 - 1.8e-53 180.9 8.0 1.8e-53 180.9 8.0 4.8 5 1 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EGG19426.1 - 2.2e-37 128.4 0.3 2.2e-37 128.4 0.3 4.7 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGG19426.1 - 1.3e-06 28.1 14.7 2.8e-06 27.1 0.2 6.1 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) PI_PP_C PF18365.1 EGG19426.1 - 0.018 15.0 0.1 0.27 11.2 0.1 3.1 2 0 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain NgoMIV_restric PF09015.10 EGG19426.1 - 0.018 14.2 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 NgoMIV restriction enzyme DUF3232 PF11554.8 EGG19426.1 - 0.12 12.8 0.2 21 5.5 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3232) ATP-synt_ab PF00006.25 EGG19428.1 - 3.6e-62 209.8 0.0 6.3e-62 209.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGG19428.1 - 1.4e-17 64.0 1.2 6.4e-16 58.6 1.2 2.6 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain SecA_SW PF07516.13 EGG19428.1 - 0.0031 17.6 2.3 0.0037 17.4 1.0 1.7 2 0 0 2 2 2 1 SecA Wing and Scaffold domain NB-ARC PF00931.22 EGG19428.1 - 0.004 16.4 0.9 0.011 15.0 0.2 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 EGG19428.1 - 0.034 14.5 0.7 0.16 12.3 0.2 2.3 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 EGG19428.1 - 0.036 14.0 0.1 0.099 12.6 0.1 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EGG19428.1 - 0.038 14.4 0.1 0.54 10.7 0.0 2.8 4 0 0 4 4 2 0 RNA helicase AAA PF00004.29 EGG19428.1 - 0.049 14.1 0.0 0.25 11.8 0.0 2.3 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EGG19428.1 - 0.09 12.7 0.3 0.25 11.2 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EGG19428.1 - 0.14 12.6 0.4 0.71 10.4 0.1 2.3 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 EGG19428.1 - 0.15 12.4 0.5 0.52 10.6 0.2 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EGG19428.1 - 0.21 10.9 1.9 0.2 11.0 0.2 1.9 2 0 0 2 2 2 0 KaiC DUF2884 PF11101.8 EGG19428.1 - 0.42 10.1 4.7 0.12 11.8 1.2 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) TrwB_AAD_bind PF10412.9 EGG19428.1 - 0.66 8.8 2.9 0.95 8.3 0.1 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SNF2_N PF00176.23 EGG19429.1 - 1e-54 185.6 0.0 1.8e-54 184.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG19429.1 - 1.2e-16 61.0 0.0 1.2e-15 57.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG19429.1 - 2.3e-10 40.8 0.0 2.3e-10 40.8 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF2439 PF10382.9 EGG19429.1 - 3.5e-05 24.0 0.5 3.5e-05 24.0 0.5 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2439) RWD PF05773.22 EGG19430.1 - 2.9e-17 63.0 0.0 6.4e-13 49.0 0.0 2.5 1 1 1 2 2 2 2 RWD domain DFRP_C PF16543.5 EGG19430.1 - 3.4e-08 33.8 2.1 3.4e-08 33.8 2.1 2.3 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 SURF1 PF02104.15 EGG19431.1 - 3.6e-34 118.5 0.0 4.3e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 SURF1 family BRCA-2_OB1 PF09103.10 EGG19432.1 - 2.9e-38 130.6 0.0 9e-38 129.0 0.0 1.9 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 EGG19432.1 - 3.5e-16 59.4 0.1 2.6e-15 56.6 0.1 2.4 2 0 0 2 2 2 1 BRCA2, helical Archease PF01951.16 EGG19433.1 - 3.1e-33 114.9 2.0 6.8e-33 113.8 1.1 1.8 2 0 0 2 2 2 1 Archease protein family (MTH1598/TM1083) CRM1_repeat PF18777.1 EGG19434.1 - 0.066 12.7 0.2 0.18 11.3 0.2 1.7 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat HscB_4_cys PF18256.1 EGG19434.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif UPF0261 PF06792.11 EGG19435.1 - 0.046 12.6 0.6 4.2 6.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0261) Romo1 PF10247.9 EGG19436.1 - 0.015 15.7 0.4 0.034 14.5 0.4 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 UIM PF02809.20 EGG19436.1 - 0.062 13.2 1.0 0.16 11.9 1.0 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Spore_YhaL PF14147.6 EGG19436.1 - 9.2 6.0 6.1 3 7.6 0.2 3.4 2 0 0 2 2 2 0 Sporulation protein YhaL RNase_PH PF01138.21 EGG19437.1 - 5e-26 91.8 0.1 1.3e-25 90.4 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGG19437.1 - 6.8e-11 42.1 0.0 1.6e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 ESP PF16590.5 EGG19437.1 - 0.054 13.8 0.2 0.054 13.8 0.2 1.9 2 0 0 2 2 2 0 Exocrine gland-secreting peptide NPR2 PF06218.11 EGG19438.1 - 6.6e-93 311.9 17.1 2.3e-78 263.9 16.5 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 DDHD PF02862.17 EGG19438.1 - 0.00012 22.4 3.4 0.00015 22.0 3.4 1.3 1 0 0 1 1 1 1 DDHD domain NPR3 PF03666.13 EGG19438.1 - 0.00046 19.1 30.9 0.011 14.6 0.0 4.4 2 1 2 4 4 3 2 Nitrogen Permease regulator of amino acid transport activity 3 DUF702 PF05142.12 EGG19438.1 - 0.012 16.1 10.6 0.018 15.5 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) TFIIA PF03153.13 EGG19438.1 - 0.013 15.5 41.4 0.018 15.0 41.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 EGG19438.1 - 0.02 13.9 18.0 0.028 13.4 18.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 EGG19438.1 - 0.021 15.0 12.2 0.033 14.4 12.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Membralin PF09746.9 EGG19438.1 - 0.047 12.7 12.8 0.067 12.2 12.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein Afi1 PF07792.12 EGG19438.1 - 0.072 13.6 23.0 6 7.4 23.0 2.9 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking ABC2_membrane_2 PF12679.7 EGG19438.1 - 0.19 11.0 1.1 0.23 10.7 1.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein EPL1 PF10513.9 EGG19438.1 - 0.2 12.1 14.9 0.44 10.9 14.9 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like SLC12 PF03522.15 EGG19438.1 - 0.21 10.6 20.8 0.29 10.1 20.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Med13_C PF06333.12 EGG19438.1 - 0.22 10.7 17.5 0.31 10.3 17.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Pet20 PF08692.10 EGG19438.1 - 0.32 11.7 7.6 2.1 9.1 7.6 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 DUF778 PF05608.12 EGG19438.1 - 0.36 11.2 5.8 0.51 10.7 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) TERB2 PF15101.6 EGG19438.1 - 0.39 10.8 23.3 0.75 9.8 23.3 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 EGG19438.1 - 0.45 9.2 19.1 0.69 8.6 19.1 1.2 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 EGG19438.1 - 0.53 10.0 15.6 0.85 9.4 15.6 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MMR1 PF08505.10 EGG19438.1 - 0.76 10.0 24.2 1.1 9.4 24.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Gti1_Pac2 PF09729.9 EGG19438.1 - 0.8 9.8 13.7 1.3 9.1 13.7 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4175 PF13779.6 EGG19438.1 - 0.94 7.3 42.4 1.2 7.0 42.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Exonuc_VII_L PF02601.15 EGG19438.1 - 0.96 8.9 23.0 1.6 8.3 23.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Velvet PF11754.8 EGG19438.1 - 1.2 9.1 17.1 1.7 8.5 17.1 1.2 1 0 0 1 1 1 0 Velvet factor Neur_chan_memb PF02932.16 EGG19438.1 - 1.2 9.1 12.4 1.8 8.5 12.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GREB1 PF15782.5 EGG19438.1 - 1.3 6.1 19.6 1.6 5.7 19.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ALMT PF11744.8 EGG19438.1 - 1.3 7.8 19.1 1.8 7.3 19.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter XRN_M PF17846.1 EGG19438.1 - 1.7 7.5 12.3 2.7 6.8 10.5 2.0 2 0 0 2 2 2 0 Xrn1 helical domain PA26 PF04636.13 EGG19438.1 - 1.8 7.4 17.2 2.6 6.9 17.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ABC2_membrane_3 PF12698.7 EGG19438.1 - 1.8 7.6 17.2 2.9 6.9 17.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Phage_GPO PF05929.11 EGG19438.1 - 1.9 8.0 18.3 3.1 7.3 18.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Pex14_N PF04695.13 EGG19438.1 - 2.1 9.0 27.1 4.4 8.0 27.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF617 PF04759.13 EGG19438.1 - 2.7 8.0 6.4 4.5 7.3 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF617 CobT PF06213.12 EGG19438.1 - 2.9 7.2 19.5 4.1 6.7 19.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MMU163 PF17119.5 EGG19438.1 - 3.2 6.8 9.7 4.7 6.3 9.7 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Ndc1_Nup PF09531.10 EGG19438.1 - 3.3 6.3 18.2 4.7 5.8 18.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1387 PF07139.11 EGG19438.1 - 3.3 7.3 21.1 4.9 6.8 21.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Mcm10 PF09332.11 EGG19438.1 - 3.4 7.0 21.2 4.8 6.5 21.2 1.2 1 0 0 1 1 1 0 Mcm10 replication factor DUF935 PF06074.12 EGG19438.1 - 3.8 6.1 17.1 5.2 5.7 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Suf PF05843.14 EGG19438.1 - 4.6 7.1 20.5 8.7 6.2 20.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Lin-8 PF03353.15 EGG19438.1 - 6.1 6.3 23.4 9 5.8 23.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 EGG19438.1 - 6.7 4.9 34.7 9.1 4.4 34.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mucin PF01456.17 EGG19438.1 - 6.8 6.7 7.3 12 5.9 7.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein LMBR1 PF04791.16 EGG19438.1 - 7.9 5.3 12.3 11 4.8 12.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CSRNP_N PF16019.5 EGG19438.1 - 8.2 6.3 18.5 13 5.6 18.5 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Zip PF02535.22 EGG19438.1 - 9.6 5.3 6.7 13 4.8 6.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SAP PF02037.27 EGG19439.1 - 0.00015 21.5 0.0 0.003 17.3 0.0 2.5 2 0 0 2 2 2 1 SAP domain PCI PF01399.27 EGG19440.1 - 1.4e-09 38.4 1.0 2.2e-09 37.8 1.0 1.4 1 0 0 1 1 1 1 PCI domain Thioredoxin PF00085.20 EGG19441.1 - 1.1e-10 41.4 0.0 1.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 EGG19441.1 - 8.8e-05 21.6 0.5 0.00011 21.3 0.5 1.1 1 0 0 1 1 1 1 Phosducin EF-1_beta_acid PF10587.9 EGG19441.1 - 0.011 16.1 3.9 0.011 16.1 3.9 2.0 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Thioredoxin_2 PF13098.6 EGG19441.1 - 0.026 15.0 0.0 0.054 14.0 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain SF3A2 PF16835.5 EGG19442.1 - 1.5e-35 121.5 0.0 3.2e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EGG19442.1 - 4.9e-06 26.7 1.6 4.9e-06 26.7 1.6 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EGG19442.1 - 0.00011 22.2 1.3 0.00016 21.6 0.7 1.6 1 1 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Dicty_CTDC PF00526.18 EGG19444.1 - 1.2e-103 338.5 673.8 3.9e-10 39.4 8.8 38.6 34 7 5 39 39 39 29 Dictyostelium (slime mold) repeat SH3_9 PF14604.6 EGG19445.1 - 2.1e-12 46.7 0.4 4.6e-12 45.6 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGG19445.1 - 2.6e-12 46.1 0.1 2.6e-12 46.1 0.1 2.5 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EGG19445.1 - 4.7e-10 39.0 0.1 9e-10 38.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain NAT PF04768.13 EGG19446.1 - 5.3e-35 120.6 0.0 1.9e-34 118.8 0.0 2.0 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 EGG19446.1 - 4.1e-07 29.9 0.0 8.7e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Amino acid kinase family Zip PF02535.22 EGG19446.1 - 0.0018 17.6 0.2 0.0018 17.6 0.2 2.8 2 2 0 2 2 1 1 ZIP Zinc transporter DUF4484 PF14831.6 EGG19446.1 - 0.0056 16.8 1.1 0.023 14.7 1.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Acetyltransf_1 PF00583.25 EGG19446.1 - 0.01 16.0 0.0 0.058 13.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG19446.1 - 0.046 13.7 0.0 0.61 10.0 0.0 2.3 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain EphA2_TM PF14575.6 EGG19446.1 - 0.28 12.1 1.1 1.1 10.2 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Serinc PF03348.15 EGG19446.1 - 0.68 8.8 3.4 0.39 9.6 0.9 1.7 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF3402 PF11882.8 EGG19446.1 - 0.74 8.8 11.7 0.048 12.8 5.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) PigN PF04987.14 EGG19446.1 - 0.86 8.4 4.2 0.25 10.2 0.6 1.8 2 0 0 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) Connexin PF00029.19 EGG19446.1 - 0.92 9.2 4.0 1 9.1 1.5 2.2 2 1 0 2 2 2 0 Connexin ABC2_membrane_3 PF12698.7 EGG19447.1 - 7.7e-53 179.8 45.4 1.9e-26 93.0 21.7 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 EGG19447.1 - 9.4e-52 175.2 0.8 8.5e-26 91.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EGG19447.1 - 2.4e-13 50.6 2.1 8.8e-06 25.7 0.0 4.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system GATase_7 PF13537.6 EGG19447.1 - 6.2e-09 35.8 0.0 3.9e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGG19447.1 - 3.6e-08 33.7 0.0 1.3e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EGG19447.1 - 5.5e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SMC_N PF02463.19 EGG19447.1 - 6.6e-05 22.5 0.0 0.61 9.5 0.0 3.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGG19447.1 - 0.0012 19.0 0.2 1.3 9.4 0.0 3.7 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 EGG19447.1 - 0.0013 18.4 0.6 0.97 9.0 0.1 2.6 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain ABC2_membrane PF01061.24 EGG19447.1 - 0.0023 17.4 26.9 0.0045 16.4 9.4 3.0 2 1 0 2 2 2 2 ABC-2 type transporter AAA_29 PF13555.6 EGG19447.1 - 0.003 17.3 2.0 0.33 10.7 0.2 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EGG19447.1 - 0.23 11.1 0.2 11 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGG19447.1 - 0.65 9.9 5.9 0.5 10.3 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase AAA_23 PF13476.6 EGG19447.1 - 3.2 8.2 9.5 3.1 8.3 0.1 2.9 3 0 0 3 3 2 0 AAA domain Zw10 PF06248.13 EGG19448.1 - 5.8e-37 127.5 23.8 5.3e-25 88.0 13.2 2.9 1 1 1 2 2 2 2 Centromere/kinetochore Zw10 Myc-LZ PF02344.15 EGG19448.1 - 1.4 9.1 11.7 0.059 13.5 2.7 3.1 3 0 0 3 3 3 0 Myc leucine zipper domain Vps26 PF03643.15 EGG19449.1 - 9e-128 425.0 6.0 1.1e-127 424.8 6.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EGG19449.1 - 5.8e-05 23.2 0.9 0.051 13.6 0.1 3.1 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain tRNA-synt_2 PF00152.20 EGG19450.1 - 1.7e-97 326.3 0.0 2.5e-97 325.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGG19450.1 - 5.4e-10 39.1 0.1 1.7e-09 37.5 0.1 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain GAD PF02938.14 EGG19450.1 - 2.7e-05 24.3 0.0 4.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.20 EGG19450.1 - 0.0088 15.5 0.1 0.091 12.2 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) UPF0560 PF10577.9 EGG19451.1 - 3.4 6.1 20.2 4.7 5.6 20.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 IMUP PF15761.5 EGG19451.1 - 6.8 7.4 11.0 5.9 7.6 9.4 1.7 1 1 1 2 2 2 0 Immortalisation up-regulated protein Gln-synt_C PF00120.24 EGG19452.1 - 2e-92 309.9 0.0 2.4e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 EGG19452.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain Hat1_N PF10394.9 EGG19453.1 - 1.8e-29 103.1 7.0 1.8e-29 103.1 7.0 2.8 2 1 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus DUF1645 PF07816.11 EGG19453.1 - 0.00017 22.2 5.0 0.00032 21.3 5.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) Acetyltransf_1 PF00583.25 EGG19453.1 - 0.00022 21.5 0.0 0.00051 20.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 EGG19453.1 - 0.00075 19.2 0.1 0.0026 17.5 0.1 1.9 1 0 0 1 1 1 1 MOZ/SAS family SR-25 PF10500.9 EGG19453.1 - 0.0049 16.5 18.8 0.0049 16.5 18.8 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Acetyltransf_10 PF13673.7 EGG19453.1 - 0.028 14.3 0.1 0.096 12.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Med15 PF09606.10 EGG19453.1 - 0.036 12.8 5.9 0.05 12.3 5.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Acetyltransf_7 PF13508.7 EGG19453.1 - 0.077 13.4 0.2 0.22 12.0 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3446 PF11928.8 EGG19453.1 - 0.092 13.1 16.0 0.23 11.8 16.0 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain Presenilin PF01080.17 EGG19453.1 - 0.95 8.2 5.6 1.6 7.4 5.6 1.2 1 0 0 1 1 1 0 Presenilin SWIM PF04434.17 EGG19454.1 - 5.7e-06 25.9 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 SWIM zinc finger DNA_pol_phi PF04931.13 EGG19454.1 - 0.0007 17.8 16.7 0.00082 17.6 16.7 1.1 1 0 0 1 1 1 1 DNA polymerase phi DUF2457 PF10446.9 EGG19454.1 - 0.0035 16.6 21.2 0.0041 16.3 21.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) PPP4R2 PF09184.11 EGG19454.1 - 0.0061 16.2 9.8 0.0068 16.0 9.8 1.2 1 0 0 1 1 1 1 PPP4R2 Cwf_Cwc_15 PF04889.12 EGG19454.1 - 0.012 15.4 17.8 0.015 15.0 17.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 EGG19454.1 - 0.019 14.4 7.5 0.019 14.3 7.5 1.1 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.11 EGG19454.1 - 0.019 15.0 9.4 0.026 14.6 9.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 EGG19454.1 - 0.028 14.8 24.4 0.062 13.7 24.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 EGG19454.1 - 0.029 12.6 14.9 0.034 12.4 14.9 1.0 1 0 0 1 1 1 0 Nop14-like family SpoIIIAH PF12685.7 EGG19454.1 - 0.15 11.8 6.4 0.21 11.4 6.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein TFB6 PF17110.5 EGG19454.1 - 0.16 11.7 5.3 0.2 11.4 5.3 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Sigma70_ner PF04546.13 EGG19454.1 - 0.17 11.8 13.2 0.23 11.3 13.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RNA_pol_3_Rpc31 PF11705.8 EGG19454.1 - 0.24 11.6 19.9 0.31 11.3 19.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 EGG19454.1 - 0.37 10.2 15.1 0.45 9.9 15.1 1.1 1 0 0 1 1 1 0 SDA1 Astro_capsid_p PF12226.8 EGG19454.1 - 0.52 9.4 15.6 0.72 8.9 15.6 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CobT PF06213.12 EGG19454.1 - 0.56 9.6 13.9 0.72 9.2 13.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Dicty_REP PF05086.12 EGG19454.1 - 0.92 7.4 11.3 1.1 7.1 11.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RPA43_OB PF17875.1 EGG19454.1 - 1.3 9.7 3.9 2.1 9.0 3.9 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DUF2722 PF10846.8 EGG19454.1 - 1.3 7.8 7.1 1.6 7.6 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF3295 PF11702.8 EGG19454.1 - 2.2 7.5 12.1 2.5 7.3 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Sporozoite_P67 PF05642.11 EGG19454.1 - 2.4 6.1 11.6 2.9 5.9 11.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.11 EGG19454.1 - 2.7 6.4 14.7 3 6.3 14.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.13 EGG19454.1 - 8 6.3 14.8 7.9 6.4 14.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C1 PF00112.23 EGG19455.1 - 1.1e-60 205.4 17.7 1e-58 199.0 12.1 2.1 1 1 1 2 2 2 2 Papain family cysteine protease Ribonuclease_3 PF00636.26 EGG19456.1 - 3.6e-37 127.2 4.5 1e-17 64.7 0.1 4.6 3 2 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGG19456.1 - 1.4e-32 112.6 0.1 3.3e-15 56.4 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease-III-like dsrm PF00035.26 EGG19456.1 - 3.2e-08 34.2 0.1 3.2e-08 34.2 0.1 2.2 2 0 0 2 2 2 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EGG19456.1 - 3.9e-05 23.8 0.0 0.00016 21.9 0.0 2.1 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 Gal11_ABD1 PF18535.1 EGG19456.1 - 0.04 14.0 0.7 2.9 8.0 0.7 2.9 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) FAM76 PF16046.5 EGG19456.1 - 4.4 6.6 12.8 0.015 14.6 2.9 1.9 2 0 0 2 2 2 0 FAM76 protein Mucin PF01456.17 EGG19457.1 - 0.028 14.4 9.3 0.063 13.3 9.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 EGG19457.1 - 0.05 11.8 6.0 0.071 11.3 6.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 EGG19457.1 - 0.12 12.4 5.7 0.23 11.5 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PBP1_TM PF14812.6 EGG19458.1 - 0.019 15.3 2.6 0.019 15.3 2.6 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PI3K_1B_p101 PF10486.9 EGG19458.1 - 0.03 12.1 6.1 0.037 11.8 6.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Cwf_Cwc_15 PF04889.12 EGG19458.1 - 0.054 13.2 15.8 0.085 12.6 15.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.9 EGG19458.1 - 0.16 10.5 7.9 0.18 10.3 7.9 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 EGG19458.1 - 0.23 10.2 7.3 0.32 9.7 7.3 1.2 1 0 0 1 1 1 0 Presenilin Trypan_PARP PF05887.11 EGG19458.1 - 0.31 11.0 4.3 3.1 7.8 0.3 2.3 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) ALMT PF11744.8 EGG19458.1 - 0.39 9.5 3.7 0.53 9.1 3.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter BUD22 PF09073.10 EGG19458.1 - 0.46 9.8 17.5 0.63 9.3 17.5 1.1 1 0 0 1 1 1 0 BUD22 TLP-20 PF06088.11 EGG19458.1 - 0.5 10.2 17.2 2.3 8.1 7.4 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) MAPKK1_Int PF08923.10 EGG19459.1 - 1.1e-21 76.8 0.9 1.3e-21 76.6 0.9 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Robl_LC7 PF03259.17 EGG19459.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Roadblock/LC7 domain RWP-RK PF02042.15 EGG19461.1 - 6e-23 80.6 0.0 1.2e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain CBF PF03914.17 EGG19462.1 - 0.012 15.7 0.2 0.022 14.8 0.2 1.5 1 0 0 1 1 1 0 CBF/Mak21 family POTRA_1 PF08478.10 EGG19462.1 - 0.52 10.6 4.3 3.7 7.9 0.4 2.9 1 1 0 2 2 2 0 POTRA domain, FtsQ-type Aldose_epim PF01263.20 EGG19463.1 - 1.4e-45 155.9 0.3 1.6e-45 155.7 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase ABC2_membrane PF01061.24 EGG19464.1 - 1.1e-85 286.4 62.4 4.6e-44 150.3 25.3 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGG19464.1 - 2.5e-38 131.7 0.0 4.9e-19 69.2 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ICMT PF04140.14 EGG19464.1 - 4.7e-28 97.4 0.0 2.1e-27 95.3 0.0 2.2 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PDR_CDR PF06422.12 EGG19464.1 - 2.3e-13 49.9 2.7 2.3e-13 49.9 2.7 4.8 4 1 0 4 4 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 EGG19464.1 - 6.6e-09 35.3 58.8 3.1e-08 33.1 15.8 3.6 3 1 0 3 3 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 EGG19464.1 - 6.8e-09 36.2 0.2 1.9e-08 34.8 0.2 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal PEMT PF04191.13 EGG19464.1 - 8.1e-08 32.6 0.5 7e-07 29.6 0.5 2.8 1 1 0 1 1 1 1 Phospholipid methyltransferase AAA_21 PF13304.6 EGG19464.1 - 3.8e-07 30.2 0.0 0.0031 17.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGG19464.1 - 2.9e-05 24.0 0.1 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGG19464.1 - 7.3e-05 22.4 0.2 0.014 15.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG19464.1 - 0.002 18.6 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EGG19464.1 - 0.0023 17.7 0.2 2.2 7.9 0.6 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGG19464.1 - 0.0032 17.8 0.1 0.86 10.0 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_25 PF13481.6 EGG19464.1 - 0.004 16.7 0.0 0.009 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGG19464.1 - 0.0044 17.3 0.1 0.62 10.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EGG19464.1 - 0.026 14.9 0.3 6.6 7.2 0.1 3.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EGG19464.1 - 0.029 13.7 0.0 0.98 8.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 EGG19464.1 - 0.07 13.0 0.5 7.4 6.4 0.0 3.1 3 0 0 3 3 3 0 NTPase cobW PF02492.19 EGG19464.1 - 0.077 12.6 0.8 0.35 10.5 0.3 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EGG19464.1 - 0.08 13.4 0.1 0.08 13.4 0.1 3.4 4 0 0 4 4 3 0 AAA domain MMR_HSR1 PF01926.23 EGG19464.1 - 0.084 13.0 0.6 4.2 7.5 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EGG19464.1 - 0.085 13.0 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGG19464.1 - 0.18 12.3 0.0 1 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EGG19464.1 - 0.23 10.5 0.0 0.4 9.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC2_membrane_2 PF12679.7 EGG19464.1 - 0.27 10.5 11.4 1.4 8.1 3.5 2.9 3 0 0 3 3 3 0 ABC-2 family transporter protein DarT PF14487.6 EGG19465.1 - 6.6e-27 94.7 1.3 8.3e-27 94.3 1.3 1.1 1 0 0 1 1 1 1 ssDNA thymidine ADP-ribosyltransferase, DarT Peptidase_M76 PF09768.9 EGG19466.1 - 1.9e-50 171.0 5.2 3.1e-50 170.3 5.2 1.3 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EGG19466.1 - 0.012 15.5 0.2 0.031 14.1 0.2 1.7 1 0 0 1 1 1 0 SprT-like family DUF1002 PF06207.11 EGG19466.1 - 7 6.1 13.3 12 5.4 13.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) zf-CCCH PF00642.24 EGG19467.1 - 1.3e-16 60.0 21.3 3.5e-05 23.6 1.7 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGG19467.1 - 6.8e-16 57.7 27.8 1.1e-06 28.4 3.4 3.4 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH_4 PF18044.1 EGG19467.1 - 2.3e-09 36.8 20.3 2.7e-05 23.8 0.2 3.5 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 EGG19467.1 - 5.3e-09 36.7 24.9 0.00098 19.8 1.1 4.1 1 1 3 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 EGG19467.1 - 2.8e-07 30.7 2.8 2.8e-07 30.7 2.8 2.8 1 1 2 3 3 3 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGG19467.1 - 0.00016 22.0 28.2 0.0022 18.4 5.7 3.5 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger Flg_bb_rod PF00460.20 EGG19467.1 - 0.98 9.4 8.3 3 7.9 0.7 2.6 2 0 0 2 2 2 0 Flagella basal body rod protein Keratin_2_head PF16208.5 EGG19467.1 - 1.9 8.6 28.5 2.8 8.0 28.5 1.2 1 0 0 1 1 1 0 Keratin type II head Activator_LAG-3 PF11498.8 EGG19467.1 - 6 5.7 18.9 8.1 5.3 18.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 API5 PF05918.11 EGG19467.1 - 8.5 5.1 12.3 12 4.5 12.3 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) BCNT PF07572.12 EGG19469.1 - 1.1e-18 67.1 3.0 1.1e-18 67.1 3.0 2.1 2 1 0 2 2 2 1 Bucentaur or craniofacial development RRN3 PF05327.11 EGG19469.1 - 0.83 8.1 19.1 1.2 7.6 19.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GREB1 PF15782.5 EGG19469.1 - 3.4 4.6 22.4 3.8 4.5 22.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peptidase_S64 PF08192.11 EGG19469.1 - 5.3 5.4 24.2 5.8 5.3 24.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 FA_desaturase PF00487.24 EGG19470.1 - 4.7e-19 69.2 36.8 9.5e-16 58.4 20.5 3.5 2 1 0 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 EGG19470.1 - 2.1e-12 47.0 0.0 1.5e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain YibE_F PF07907.11 EGG19470.1 - 0.0064 16.0 1.0 0.0064 16.0 1.0 2.6 3 0 0 3 3 3 2 YibE/F-like protein DUF3337 PF11816.8 EGG19471.1 - 0.079 12.8 0.1 0.079 12.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Ceramidase_alk PF04734.13 EGG19472.1 - 8.2e-216 717.5 0.0 9.8e-216 717.3 0.0 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EGG19472.1 - 3e-52 176.9 0.8 5.4e-52 176.0 0.8 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Tetraspanin PF00335.20 EGG19473.1 - 0.14 11.9 9.9 0.48 10.1 9.6 1.7 1 1 1 2 2 2 0 Tetraspanin family Wzy_C PF04932.15 EGG19473.1 - 9.6 5.8 12.3 62 3.2 12.3 2.1 1 1 0 1 1 1 0 O-Antigen ligase Ank_4 PF13637.6 EGG19474.1 - 0.17 12.5 0.5 0.82 10.3 0.1 2.4 2 2 1 3 3 3 0 Ankyrin repeats (many copies) RRM_1 PF00076.22 EGG19476.1 - 1e-18 66.9 0.1 5e-09 35.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R3H PF01424.22 EGG19476.1 - 9.9e-11 41.5 0.0 2.6e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 R3H domain Limkain-b1 PF11608.8 EGG19476.1 - 2e-05 24.5 0.0 0.074 13.1 0.0 2.8 2 0 0 2 2 2 2 Limkain b1 DbpA PF03880.15 EGG19476.1 - 0.018 15.0 0.0 4.2 7.4 0.0 2.7 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_3 PF08777.11 EGG19476.1 - 0.16 12.0 0.1 14 5.8 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 EGG19476.1 - 0.19 11.8 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DIL PF01843.19 EGG19477.1 - 3.8e-24 85.0 1.0 1.1e-23 83.5 1.0 1.9 1 0 0 1 1 1 1 DIL domain NT-C2 PF10358.9 EGG19477.1 - 1.2e-21 76.9 8.7 2.6e-21 75.9 8.7 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SlyX PF04102.12 EGG19477.1 - 0.61 10.8 19.1 4 8.1 3.4 4.0 1 1 2 3 3 3 0 SlyX Secretin_N_2 PF07655.13 EGG19478.1 - 0.55 10.8 12.0 0.55 10.8 12.0 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain Menin PF05053.13 EGG19478.1 - 2.7 6.2 10.5 2.9 6.1 10.5 1.0 1 0 0 1 1 1 0 Menin RICTOR_N PF14664.6 EGG19479.1 - 1.2e-92 310.8 3.9 1.8e-92 310.3 3.9 1.2 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term vATP-synt_E PF01991.18 EGG19479.1 - 0.063 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit RasGEF_N_2 PF14663.6 EGG19480.1 - 1.3e-32 112.4 0.0 2.4e-31 108.3 0.0 2.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 EGG19480.1 - 3.5e-32 110.3 0.0 8.6e-27 92.9 0.1 3.7 3 0 0 3 3 3 3 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 EGG19480.1 - 6.6e-30 103.2 0.5 1.5e-26 92.4 0.1 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.6 EGG19480.1 - 3.1e-06 27.5 0.0 0.14 12.5 0.0 3.3 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 EGG19480.1 - 0.00018 21.5 0.6 29 5.3 0.1 4.9 4 0 0 4 4 4 0 HEAT repeat HEAT_PBS PF03130.16 EGG19480.1 - 0.035 14.8 0.0 0.81 10.5 0.0 3.1 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Adaptin_N PF01602.20 EGG19480.1 - 0.043 12.4 0.1 0.096 11.2 0.0 1.5 2 0 0 2 2 2 0 Adaptin N terminal region Proteasom_PSMB PF10508.9 EGG19480.1 - 0.082 11.4 0.0 3.1 6.2 0.0 2.8 1 1 2 3 3 3 0 Proteasome non-ATPase 26S subunit Q_salvage PF10343.9 EGG19481.1 - 1.1e-34 120.3 0.4 2.8e-34 119.0 0.0 1.8 2 0 0 2 2 2 1 Potential Queuosine, Q, salvage protein family Podoplanin PF05808.11 EGG19482.1 - 0.0051 16.9 0.2 0.01 16.0 0.2 1.4 1 0 0 1 1 1 1 Podoplanin EGF_2 PF07974.13 EGG19482.1 - 0.0098 16.2 8.1 0.0098 16.2 8.1 2.4 2 0 0 2 2 2 1 EGF-like domain T3SS_needle_F PF09392.10 EGG19482.1 - 0.1 12.8 2.5 0.25 11.6 2.5 1.6 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF MpPF26 PF07666.11 EGG19482.1 - 0.14 12.3 2.1 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 M penetrans paralogue family 26 AhpC-TSA PF00578.21 EGG19483.1 - 2.3e-38 130.9 0.1 3.9e-38 130.2 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 EGG19483.1 - 6.3e-18 64.9 0.0 8.6e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGG19483.1 - 1.4e-10 40.8 0.0 2.3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EGG19483.1 - 0.028 14.3 0.1 0.058 13.3 0.1 1.5 1 0 0 1 1 1 0 SCO1/SenC CAF1A PF12253.8 EGG19484.1 - 0.015 15.4 2.3 0.027 14.6 2.3 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A PRIMA1 PF16101.5 EGG19485.1 - 0.017 15.2 0.8 0.025 14.6 0.8 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SUIM_assoc PF16619.5 EGG19485.1 - 1.3 9.2 10.2 0.64 10.1 4.7 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Mito_fiss_reg PF05308.11 EGG19485.1 - 1.4 9.0 8.6 2.2 8.3 8.6 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator LRR_8 PF13855.6 EGG19487.1 - 0.0098 15.6 5.2 0.025 14.3 0.2 3.7 2 1 1 3 3 3 1 Leucine rich repeat SR-25 PF10500.9 EGG19487.1 - 0.42 10.2 3.1 0.76 9.3 3.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein hEGF PF12661.7 EGG19487.1 - 0.59 10.8 11.2 2 9.2 11.2 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.13 EGG19487.1 - 0.64 10.4 13.7 1.5 9.2 13.7 1.6 1 0 0 1 1 1 0 EGF-like domain AAA_23 PF13476.6 EGG19489.1 - 4.3e-19 69.8 49.3 4.3e-19 69.8 49.3 8.5 1 1 3 4 4 1 1 AAA domain AAA_21 PF13304.6 EGG19489.1 - 1.1e-09 38.6 12.2 1.6e-05 24.9 0.0 4.3 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG19489.1 - 1.4e-07 31.2 0.0 1.4e-07 31.2 0.0 3.9 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGG19489.1 - 0.00031 20.9 0.0 0.00097 19.3 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 EGG19489.1 - 0.005 15.6 0.0 0.005 15.6 0.0 7.2 2 1 4 6 6 5 2 AAA domain ABC_tran PF00005.27 EGG19489.1 - 0.011 16.3 0.0 0.011 16.3 0.0 8.4 2 1 2 4 4 2 0 ABC transporter AAA_29 PF13555.6 EGG19489.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EGG19489.1 - 0.11 12.1 125.8 0.018 14.7 27.7 6.2 1 1 3 4 4 2 0 AAA ATPase domain AAA_16 PF13191.6 EGG19489.1 - 0.17 12.3 0.0 0.17 12.3 0.0 5.0 2 1 2 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 EGG19489.1 - 2.6 8.3 0.0 2.6 8.3 0.0 4.7 5 1 2 7 7 7 0 AAA domain DUF4107 PF13389.6 EGG19489.1 - 5.7 7.1 7.3 5 7.3 1.8 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) G-alpha PF00503.20 EGG19490.1 - 3e-94 316.1 16.1 3.8e-94 315.8 16.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGG19490.1 - 1e-10 41.3 0.6 1.9e-07 30.7 0.0 2.8 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG19490.1 - 1.2e-05 24.8 1.0 0.0013 18.1 0.0 2.6 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Ras PF00071.22 EGG19490.1 - 0.011 15.3 0.2 0.53 9.9 0.1 2.6 2 0 0 2 2 2 0 Ras family MMR_HSR1 PF01926.23 EGG19490.1 - 0.015 15.3 0.2 2.8 8.1 0.0 3.0 3 1 0 3 3 3 0 50S ribosome-binding GTPase Roc PF08477.13 EGG19490.1 - 0.022 15.0 3.1 2.9 8.1 0.1 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGG19490.1 - 0.025 14.1 0.0 7 6.1 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 EGG19490.1 - 0.038 13.7 0.1 0.091 12.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 EGG19490.1 - 0.05 13.0 0.4 2.1 7.8 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF3638 PF12340.8 EGG19491.1 - 7.7e-66 221.7 0.1 1.8e-65 220.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EGG19491.1 - 4.2e-15 54.8 0.0 9.2e-15 53.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF4175 PF13779.6 EGG19491.1 - 0.36 8.7 2.7 0.67 7.8 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) zf-MIZ PF02891.20 EGG19492.1 - 3.3e-19 68.4 4.3 6.7e-19 67.4 4.3 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EGG19492.1 - 1.7e-06 27.8 1.2 3.9e-06 26.6 1.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit MRNIP PF15749.5 EGG19492.1 - 0.026 15.2 1.2 0.026 15.2 1.2 5.0 3 2 1 4 4 4 0 MRN-interacting protein LRR_8 PF13855.6 EGG19493.1 - 0.0018 18.0 0.1 3.1 7.6 0.2 3.9 3 0 0 3 3 3 2 Leucine rich repeat TIG PF01833.24 EGG19493.1 - 0.0049 16.9 6.1 0.0049 16.9 6.1 4.6 4 0 0 4 4 4 1 IPT/TIG domain LRR_8 PF13855.6 EGG19494.1 - 7.9e-05 22.3 6.8 0.005 16.6 0.0 4.9 5 0 0 5 5 5 1 Leucine rich repeat hEGF PF12661.7 EGG19494.1 - 0.03 14.9 12.2 0.11 13.1 12.2 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF LRR_1 PF00560.33 EGG19494.1 - 0.24 12.1 2.7 2e+02 3.2 0.1 5.7 5 1 0 5 5 5 0 Leucine Rich Repeat DUF2970 PF11174.8 EGG19494.1 - 0.54 10.1 2.3 1.1 9.2 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) EGF_2 PF07974.13 EGG19494.1 - 0.86 10.0 15.6 2.2 8.8 15.6 1.7 1 0 0 1 1 1 0 EGF-like domain Methyltrn_RNA_3 PF02598.17 EGG19495.1 - 3.6e-65 220.3 0.9 3.6e-65 220.3 0.9 1.9 2 0 0 2 2 2 1 Putative RNA methyltransferase Cyclin PF08613.11 EGG19497.1 - 3.1e-11 43.9 0.3 0.0045 17.4 0.0 3.6 2 1 1 3 3 3 2 Cyclin Di19_C PF14571.6 EGG19497.1 - 4.6 7.8 11.1 1.9e+02 2.6 11.1 2.5 1 1 0 1 1 1 0 Stress-induced protein Di19, C-terminal Lung_7-TM_R PF06814.13 EGG19498.1 - 9.8e-50 169.5 11.1 1.4e-49 168.9 11.1 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 EGG19498.1 - 1.1e-05 25.0 16.2 1.1e-05 25.0 16.2 1.8 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain DUF3638 PF12340.8 EGG19502.1 - 1.7e-32 112.6 0.1 6.2e-32 110.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EGG19502.1 - 8.7e-17 60.2 0.6 2.1e-16 59.0 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) DUF3638 PF12340.8 EGG19503.1 - 1.1e-17 64.2 0.1 2.2e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) HIP1_clath_bdg PF16515.5 EGG19503.1 - 0.13 12.9 0.8 0.53 10.9 0.8 2.0 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3638 PF12340.8 EGG19504.1 - 1.8e-68 230.2 0.2 4.1e-68 229.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EGG19504.1 - 2.2e-16 58.9 0.1 5e-16 57.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) GlcNAc-1_reg PF18440.1 EGG19504.1 - 0.062 13.5 0.0 0.37 11.0 0.0 2.4 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain DUF3645 PF12359.8 EGG19505.1 - 1.1e-17 63.0 0.1 2.5e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF3638 PF12340.8 EGG19506.1 - 6.4e-37 127.1 0.2 2.6e-36 125.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3638 PF12340.8 EGG19507.1 - 2.9e-66 223.0 0.0 7.1e-66 221.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EGG19507.1 - 1.1e-16 59.9 0.4 7.1e-16 57.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) DUF3679 PF12438.8 EGG19507.1 - 0.0098 15.6 0.1 0.023 14.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3679) IreB PF06135.12 EGG19507.1 - 0.052 13.7 0.0 0.28 11.4 0.0 2.4 1 0 0 1 1 1 0 IreB regulatory phosphoprotein GCR1_C PF12550.8 EGG19507.1 - 0.087 13.2 0.3 16 5.9 0.0 3.5 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Rubis-subs-bind PF09273.11 EGG19507.1 - 7.6 7.2 6.7 7.1 7.3 0.1 3.5 4 0 0 4 4 4 0 Rubisco LSMT substrate-binding LIN52 PF10044.9 EGG19507.1 - 7.9 7.3 6.4 7.2 7.4 0.2 3.9 4 0 0 4 4 4 0 Retinal tissue protein SID-1_RNA_chan PF13965.6 EGG19509.1 - 1.3e-82 278.2 32.2 1.5e-82 278.0 32.2 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Rep_fac-A_C PF08646.10 EGG19510.1 - 0.018 14.8 0.1 0.018 14.8 0.1 2.8 3 0 0 3 3 3 0 Replication factor-A C terminal domain MecA PF05389.12 EGG19510.1 - 0.4 10.3 7.6 0.26 10.9 1.5 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Orf78 PF06024.12 EGG19510.1 - 3.2 8.1 10.0 4.3 7.7 2.8 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Secretin_N_2 PF07655.13 EGG19510.1 - 3.7 8.2 14.3 8.2 7.1 7.3 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Apis_Csd PF11671.8 EGG19510.1 - 7 6.7 17.8 0.63 10.1 11.0 2.3 2 0 0 2 2 2 0 Complementary sex determiner protein Pkinase_Tyr PF07714.17 EGG19511.1 - 1.4e-45 155.6 0.0 2.5e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG19511.1 - 3.2e-43 148.0 0.8 5.5e-43 147.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 EGG19511.1 - 4.8e-36 122.3 47.0 1.3e-10 40.8 5.5 9.7 4 2 5 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 EGG19511.1 - 5.3e-19 68.0 91.7 7.7e-05 23.0 0.1 13.4 13 0 0 13 13 13 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGG19511.1 - 8.1e-06 25.5 17.6 0.0017 17.9 3.1 4.6 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 EGG19511.1 - 0.032 14.7 41.3 2.5 9.0 0.3 12.6 10 1 0 10 10 10 0 Leucine Rich Repeat SUIM_assoc PF16619.5 EGG19511.1 - 0.085 12.9 9.9 0.012 15.7 2.8 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 EGF_2 PF07974.13 EGG19511.1 - 0.18 12.2 27.1 2.1 8.8 7.1 2.7 2 0 0 2 2 2 0 EGF-like domain DUF853 PF05872.12 EGG19511.1 - 2.5 6.6 5.0 4.3 5.8 5.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Pkinase PF00069.25 EGG19512.1 - 4e-26 92.0 0.0 1.4e-25 90.1 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19512.1 - 4e-25 88.6 0.0 9.3e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 EGG19512.1 - 4.5e-24 84.8 10.8 8.8e-13 48.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19512.1 - 9.3e-24 83.5 4.0 3e-05 24.5 0.0 5.7 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19512.1 - 6.1e-20 71.0 0.9 8.2e-06 26.0 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EGG19512.1 - 1.9e-18 66.0 0.2 0.00026 21.3 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EGG19512.1 - 4.5e-17 60.4 0.6 0.00011 22.3 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat SAM_1 PF00536.30 EGG19512.1 - 3e-10 40.4 0.3 6.7e-10 39.3 0.3 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGG19512.1 - 1.6e-06 28.1 0.3 3.1e-06 27.2 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) APH PF01636.23 EGG19512.1 - 0.047 13.6 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tub_N PF16322.5 EGG19512.1 - 1.5 9.2 25.9 0.11 12.8 19.6 2.3 3 0 0 3 3 3 0 Tubby N-terminal TFIIF_alpha PF05793.12 EGG19512.1 - 7.6 5.0 23.9 14 4.1 23.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ceramidase PF05875.12 EGG19513.1 - 1.8e-59 201.3 9.2 2.3e-59 201.0 9.2 1.1 1 0 0 1 1 1 1 Ceramidase DUF1764 PF08576.10 EGG19514.1 - 3.8 8.5 12.9 5.5 8.0 12.9 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) GEMIN8 PF15348.6 EGG19514.1 - 7.3 6.8 11.1 8.2 6.7 11.1 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DDE_Tnp_1_7 PF13843.6 EGG19515.1 - 5.5e-27 95.0 3.4 5.5e-27 95.0 3.4 3.6 3 1 0 3 3 3 1 Transposase IS4 Apt1 PF10351.9 EGG19515.1 - 0.0015 17.4 9.6 0.0026 16.7 9.6 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain Macoilin PF09726.9 EGG19515.1 - 0.29 9.6 14.8 0.63 8.5 14.8 1.5 1 0 0 1 1 1 0 Macoilin family CHASE3 PF05227.13 EGG19515.1 - 0.6 10.0 2.4 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 CHASE3 domain Herpes_capsid PF06112.11 EGG19515.1 - 4.2 7.4 21.6 15 5.6 21.6 2.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF2475 PF10629.9 EGG19515.1 - 4.6 7.5 6.6 26 5.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2475) Tir_receptor_C PF07489.11 EGG19516.1 - 0.012 15.6 6.2 0.027 14.5 6.2 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus LRR_4 PF12799.7 EGG19516.1 - 0.059 13.8 19.1 3 8.4 0.0 6.7 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) CDC45 PF02724.14 EGG19516.1 - 9 4.4 17.0 13 3.9 17.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1242 PF06842.12 EGG19517.1 - 0.24 11.2 1.4 18 5.2 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) Thymidylate_kin PF02223.17 EGG19517.1 - 0.43 10.2 3.9 5.3 6.7 0.1 2.9 3 1 0 3 3 3 0 Thymidylate kinase LRR_4 PF12799.7 EGG19517.1 - 2.6 8.6 40.6 13 6.4 0.6 9.6 7 2 1 8 8 8 0 Leucine Rich repeats (2 copies) TFIIS_M PF07500.14 EGG19518.1 - 1.7e-18 67.1 0.1 9.9e-18 64.7 0.1 2.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 EGG19518.1 - 3.1e-08 33.4 9.4 6.6e-08 32.3 9.4 1.6 1 0 0 1 1 1 1 PHD-finger DUF2106 PF09879.9 EGG19519.1 - 0.56 9.7 4.1 0.8 9.2 4.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) Meiotic_rec114 PF03525.14 EGG19520.1 - 0.002 17.2 1.5 0.0027 16.7 1.5 1.2 1 0 0 1 1 1 1 Meiotic recombination protein rec114 DUF3303 PF11746.8 EGG19520.1 - 0.013 15.8 0.2 0.022 15.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3303) DUF3378 PF11858.8 EGG19520.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) 23ISL PF16620.5 EGG19520.1 - 0.19 11.9 4.2 0.33 11.1 4.2 1.4 1 1 0 1 1 1 0 Unstructured linker between I-set domains 2 and 3 on MYLCK RNA_polI_A14 PF08203.11 EGG19520.1 - 0.26 12.0 4.5 0.85 10.4 3.8 2.0 1 1 1 2 2 2 0 Yeast RNA polymerase I subunit RPA14 AAA_23 PF13476.6 EGG19521.1 - 4.2 7.8 15.0 25 5.3 16.3 1.4 1 1 0 1 1 1 0 AAA domain INSIG PF07281.12 EGG19522.1 - 0.0085 15.8 0.7 0.01 15.5 0.7 1.3 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) HRG PF16954.5 EGG19522.1 - 0.01 16.2 3.4 2 8.9 3.4 2.9 1 1 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Nop PF01798.18 EGG19523.1 - 4e-18 65.7 0.2 5e-18 65.4 0.2 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin DUF999 PF06198.11 EGG19523.1 - 0.0091 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF999) Glyco_transf_10 PF00852.19 EGG19524.1 - 4.7e-36 124.1 1.3 8.8e-36 123.3 1.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Laminin_G_3 PF13385.6 EGG19524.1 - 5.2e-14 52.7 0.0 8.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Glyco_tran_10_N PF17039.5 EGG19524.1 - 0.0082 16.6 0.0 0.03 14.8 0.0 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal UPF0552 PF10574.9 EGG19525.1 - 9.5e-28 97.1 0.9 1.4e-27 96.5 0.9 1.3 1 1 0 1 1 1 1 Arp2/3-interacting proteins Arpin ANAPC4_WD40 PF12894.7 EGG19526.1 - 5.1e-17 62.0 1.5 2.3e-05 24.6 0.0 4.7 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG19526.1 - 7.1e-13 48.8 7.8 6.9e-06 26.7 0.5 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40_like PF17005.5 EGG19526.1 - 8.5e-09 35.1 2.4 3.2e-05 23.4 0.0 3.1 3 0 0 3 3 3 2 WD40-like domain Nha1_C PF08619.10 EGG19526.1 - 0.0032 16.7 0.5 0.0032 16.7 0.5 1.8 2 0 0 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus PALB2_WD40 PF16756.5 EGG19526.1 - 0.0072 15.3 0.2 0.014 14.4 0.2 1.4 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Med13_C PF06333.12 EGG19526.1 - 0.17 11.2 10.7 0.014 14.7 4.6 2.1 3 0 0 3 3 3 0 Mediator complex subunit 13 C-terminal domain HalX PF08663.10 EGG19526.1 - 0.36 11.2 4.4 0.68 10.3 4.4 1.4 1 0 0 1 1 1 0 HalX domain DUF3638 PF12340.8 EGG19527.1 - 2.5e-67 226.5 0.0 6e-67 225.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EGG19527.1 - 1.7e-16 59.3 0.1 3.4e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) YyzF PF14116.6 EGG19527.1 - 0.097 12.7 0.0 25 5.0 0.0 3.0 2 0 0 2 2 2 0 YyzF-like protein Trypan_PARP PF05887.11 EGG19530.1 - 0.00014 21.8 5.4 0.00024 21.1 5.4 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Pex14_N PF04695.13 EGG19530.1 - 0.0018 19.0 6.6 0.0027 18.4 6.6 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.10 EGG19530.1 - 0.087 11.5 10.5 0.17 10.5 10.1 1.6 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF2076 PF09849.9 EGG19530.1 - 0.8 9.7 15.0 1.5 8.8 13.5 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TFIIA PF03153.13 EGG19530.1 - 3.3 7.6 13.5 5.1 7.0 13.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 EGG19530.1 - 7.1 7.0 9.7 14 6.1 9.7 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Ank_2 PF12796.7 EGG19531.1 - 7.8e-05 23.2 0.2 1.1 10.0 0.0 4.2 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19531.1 - 0.00011 22.7 0.2 0.15 12.6 0.0 4.6 3 1 0 3 3 3 1 Ankyrin repeats (many copies) SET PF00856.28 EGG19531.1 - 0.0076 16.7 0.2 0.018 15.5 0.2 1.6 1 0 0 1 1 1 1 SET domain Ank_3 PF13606.6 EGG19531.1 - 0.062 13.9 2.5 33 5.5 0.0 5.4 5 1 1 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 EGG19532.1 - 7.6e-10 39.2 5.3 4 8.1 0.0 8.4 7 2 1 8 8 8 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG19532.1 - 0.0049 17.3 0.4 4.8e+02 1.9 0.0 8.3 9 1 1 10 10 10 0 Ankyrin repeat XPC-binding PF09280.11 EGG19534.1 - 0.14 11.9 0.6 0.53 10.1 0.1 2.3 2 0 0 2 2 2 0 XPC-binding domain Ank_2 PF12796.7 EGG19536.1 - 0.041 14.5 0.2 10 6.8 0.0 3.3 1 1 2 3 3 3 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19536.1 - 0.042 14.4 0.1 15 6.3 0.0 4.2 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG19537.1 - 3.8e-07 30.5 0.0 2.5 8.8 0.0 7.4 7 0 0 7 7 7 2 Ankyrin repeats (many copies) TEA PF01285.18 EGG19537.1 - 0.02 15.0 0.3 0.093 12.8 0.1 2.3 2 0 0 2 2 2 0 TEA/ATTS domain tRNA-synt_2d PF01409.20 EGG19540.1 - 4.5e-82 275.2 0.0 8.6e-82 274.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EGG19540.1 - 3.7e-10 39.9 0.2 7.2e-10 39.0 0.2 1.5 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EGG19540.1 - 5.1e-05 22.8 0.0 0.0014 18.1 0.0 2.4 3 0 0 3 3 3 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EGG19540.1 - 0.0002 20.6 0.2 0.00085 18.5 0.0 2.1 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD1 PF18552.1 EGG19540.1 - 0.00023 20.9 0.0 0.00067 19.4 0.0 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 1 DUF3290 PF11694.8 EGG19542.1 - 3.9 7.4 8.5 0.19 11.7 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF2207 PF09972.9 EGG19543.1 - 0.035 12.9 0.1 0.044 12.5 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PG_binding_1 PF01471.18 EGG19544.1 - 3.1e-08 33.7 0.0 7.6e-06 26.1 0.0 2.8 2 0 0 2 2 2 2 Putative peptidoglycan binding domain ATG27 PF09451.10 EGG19546.1 - 3.3e-28 99.3 0.2 4.6e-28 98.8 0.2 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 EGG19546.1 - 1.4e-10 40.7 0.9 1.9e-08 33.7 0.4 2.0 2 0 0 2 2 2 2 Mannose-6-phosphate receptor PRKCSH_1 PF13015.6 EGG19546.1 - 0.0087 15.8 1.6 0.01 15.5 0.4 1.6 1 1 1 2 2 2 1 Glucosidase II beta subunit-like protein Lectin_C PF00059.21 EGG19547.1 - 1.1e-09 39.0 12.6 0.00021 22.0 0.1 4.2 3 0 0 3 3 3 2 Lectin C-type domain TIG PF01833.24 EGG19547.1 - 5.6e-08 32.8 31.8 0.04 14.0 0.3 6.7 6 0 0 6 6 6 5 IPT/TIG domain EGF_2 PF07974.13 EGG19547.1 - 0.02 15.2 8.9 0.058 13.8 8.9 1.8 1 0 0 1 1 1 0 EGF-like domain GCD14 PF08704.10 EGG19547.1 - 1.8 8.2 6.6 3.5 7.2 6.6 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MGC-24 PF05283.11 EGG19548.1 - 0.25 11.8 4.0 0.33 11.4 4.0 1.3 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin ERM PF00769.19 EGG19549.1 - 0.0026 17.6 3.0 0.0026 17.6 3.0 1.6 2 0 0 2 2 2 1 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 EGG19549.1 - 0.0041 17.7 3.4 0.0041 17.7 3.4 2.2 2 0 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1609 PF07753.11 EGG19549.1 - 0.0088 15.6 1.9 0.0089 15.6 0.2 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1609) DUF5101 PF17031.5 EGG19549.1 - 0.011 15.8 4.1 0.011 15.8 4.1 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF5101) FapA PF03961.13 EGG19549.1 - 0.013 14.1 3.2 0.013 14.2 3.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ATG16 PF08614.11 EGG19549.1 - 0.025 14.8 6.1 0.043 14.0 6.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 EGG19549.1 - 0.057 13.5 5.3 0.13 12.3 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 EGG19549.1 - 0.096 12.1 7.8 0.019 14.4 2.8 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 SlyX PF04102.12 EGG19549.1 - 0.11 13.1 0.7 0.11 13.1 0.7 3.1 2 1 1 3 3 3 0 SlyX YabA PF06156.13 EGG19549.1 - 0.27 11.9 4.7 0.13 13.0 1.6 2.0 2 1 0 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 EGG19549.1 - 0.48 9.3 11.1 0.027 13.4 5.8 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2802 PF10975.8 EGG19549.1 - 0.54 10.4 9.7 1.9 8.6 2.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) bZIP_1 PF00170.21 EGG19549.1 - 0.66 10.1 7.0 0.27 11.3 0.4 2.4 1 1 1 2 2 2 0 bZIP transcription factor AAA_13 PF13166.6 EGG19549.1 - 0.93 8.1 8.3 3.6 6.1 8.5 1.7 1 1 1 2 2 2 0 AAA domain PRKG1_interact PF15898.5 EGG19549.1 - 1.2 10.1 12.7 0.42 11.5 0.3 2.9 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF1465 PF07323.12 EGG19549.1 - 1.8 8.4 6.8 0.09 12.6 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) FAM76 PF16046.5 EGG19549.1 - 2.3 7.5 7.3 3.3 7.0 7.3 1.1 1 0 0 1 1 1 0 FAM76 protein TMF_TATA_bd PF12325.8 EGG19549.1 - 2.6 8.3 12.5 0.14 12.4 6.8 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.6 EGG19549.1 - 6.9 7.1 15.7 1.3 9.4 10.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) BAR PF03114.18 EGG19550.1 - 7.3e-17 61.8 17.3 8.7e-17 61.6 17.3 1.0 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EGG19550.1 - 2.4e-11 43.8 13.1 3e-11 43.5 13.1 1.1 1 0 0 1 1 1 1 BAR domain of APPL family HALZ PF02183.18 EGG19550.1 - 0.0036 17.5 5.3 0.0041 17.3 1.7 2.8 2 1 0 2 2 2 1 Homeobox associated leucine zipper Sec34 PF04136.15 EGG19550.1 - 0.021 14.7 8.9 0.084 12.7 3.2 2.4 2 1 0 2 2 2 0 Sec34-like family BAR_2 PF10455.9 EGG19550.1 - 0.037 13.2 16.1 0.057 12.5 16.1 1.4 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking FAS_I_H PF18314.1 EGG19550.1 - 0.045 13.4 3.4 0.91 9.1 0.1 2.5 2 0 0 2 2 2 0 Fatty acid synthase type I helical domain Med30 PF11315.8 EGG19550.1 - 0.073 13.3 11.5 0.32 11.2 3.4 2.8 1 1 2 3 3 3 0 Mediator complex subunit 30 Tup_N PF08581.10 EGG19550.1 - 0.99 9.8 8.2 4.5 7.6 2.0 3.2 2 1 1 3 3 3 0 Tup N-terminal KELK PF15796.5 EGG19550.1 - 1.6 9.3 19.3 0.25 11.8 1.4 3.6 3 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMF_TATA_bd PF12325.8 EGG19550.1 - 2.1 8.6 13.5 0.33 11.2 7.6 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Pyr_redox PF00070.27 EGG19550.1 - 2.4 8.8 5.2 2 9.0 0.5 3.0 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Seryl_tRNA_N PF02403.22 EGG19550.1 - 2.8 8.2 15.0 5.9 7.2 8.7 3.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CDP-OH_P_transf PF01066.21 EGG19551.1 - 1.1e-07 32.5 0.2 1.1e-07 32.5 0.2 3.8 3 1 0 3 3 3 2 CDP-alcohol phosphatidyltransferase ATG_C PF09333.11 EGG19552.1 - 2.2e-16 60.0 0.3 1.3e-07 31.8 0.2 2.8 2 0 0 2 2 2 2 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EGG19552.1 - 2.8e-06 27.2 8.2 0.003 17.4 0.3 2.9 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal zf-B_box PF00643.24 EGG19552.1 - 0.0018 18.4 5.8 0.0033 17.5 5.8 1.4 1 0 0 1 1 1 1 B-box zinc finger CDC27 PF09507.10 EGG19552.1 - 1.4 8.3 37.6 0.047 13.1 18.8 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 EGG19552.1 - 8.2 4.6 27.8 1.1 7.5 6.9 2.1 2 0 0 2 2 2 0 CDC45-like protein DNA_topoisoIV PF00521.20 EGG19554.1 - 2.4e-110 369.3 12.4 1.4e-85 287.8 0.0 2.4 1 1 1 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EGG19554.1 - 2e-47 160.7 2.7 2e-47 160.7 2.7 2.7 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EGG19554.1 - 4.2e-21 75.2 0.1 4.2e-21 75.2 0.1 2.2 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 EGG19554.1 - 3.9e-13 49.9 0.0 9.7e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EGG19554.1 - 4.3e-07 30.1 0.0 1.9e-06 28.0 0.0 2.2 1 0 0 1 1 1 1 Toprim domain Pox_Ag35 PF03286.14 EGG19554.1 - 0.00067 19.5 19.4 0.00067 19.5 19.4 5.5 4 1 1 5 5 5 1 Pox virus Ag35 surface protein DUF3394 PF11874.8 EGG19554.1 - 0.0025 17.5 1.2 0.11 12.2 0.0 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3394) ABC_tran PF00005.27 EGG19555.1 - 0.0015 19.0 0.0 0.0044 17.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGG19555.1 - 0.0064 16.4 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGG19555.1 - 0.013 15.9 0.0 0.12 12.7 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 EGG19555.1 - 0.023 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-C3HC PF07967.13 EGG19555.1 - 0.069 13.2 5.7 0.23 11.5 5.7 1.9 1 0 0 1 1 1 0 C3HC zinc finger-like AAA_22 PF13401.6 EGG19555.1 - 0.069 13.4 0.0 0.26 11.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGG19555.1 - 0.082 13.0 0.1 0.36 10.9 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGG19555.1 - 0.14 12.5 1.6 2.7 8.4 0.0 3.7 3 0 0 3 3 3 0 RNA helicase AAA_21 PF13304.6 EGG19555.1 - 1.1 9.0 5.2 2.6 7.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system zf-C3HC4_2 PF13923.6 EGG19555.1 - 5.5 6.9 23.5 0.15 12.0 8.5 3.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3642 PF12182.8 EGG19556.1 - 0.2 11.9 2.3 0.52 10.6 2.3 1.6 1 0 0 1 1 1 0 Bacterial lipoprotein p450 PF00067.22 EGG19557.1 - 1.2e-84 284.7 0.0 1.3e-84 284.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF973 PF06157.11 EGG19558.1 - 0.11 11.5 0.1 0.23 10.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF4148 PF13663.6 EGG19558.1 - 0.17 12.1 0.2 0.34 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) DcpS_C PF11969.8 EGG19559.1 - 1.3e-23 83.6 2.1 2e-23 83.1 2.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EGG19559.1 - 1.5e-12 48.1 1.0 2.9e-12 47.2 1.0 1.4 1 0 0 1 1 1 1 HIT domain DUF5083 PF16890.5 EGG19559.1 - 0.016 14.9 0.0 0.05 13.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) GalP_UDP_tr_C PF02744.17 EGG19559.1 - 0.04 13.7 0.1 0.057 13.1 0.1 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Hid1 PF12722.7 EGG19560.1 - 4.4 5.3 13.5 5.3 5.0 13.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOBP PF15279.6 EGG19560.1 - 9.9 6.7 8.6 13 6.3 8.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein APC_15aa PF05972.11 EGG19561.1 - 0.022 15.0 0.3 4.9 7.6 0.2 2.9 2 0 0 2 2 2 0 APC 15 residue motif DUF4834 PF16118.5 EGG19561.1 - 0.2 12.7 4.6 0.47 11.4 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SOCS_box PF07525.16 EGG19561.1 - 4.2 7.8 8.6 26 5.3 0.0 4.7 5 0 0 5 5 5 0 SOCS box Menin PF05053.13 EGG19561.1 - 5.1 5.3 8.8 7.7 4.7 8.8 1.2 1 0 0 1 1 1 0 Menin DUF4834 PF16118.5 EGG19562.1 - 0.061 14.3 4.6 0.14 13.1 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Menin PF05053.13 EGG19562.1 - 0.82 7.9 8.2 1.1 7.5 8.2 1.1 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.13 EGG19562.1 - 6.8 7.3 20.3 0.73 10.4 15.6 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain WD40 PF00400.32 EGG19563.1 - 0.0018 19.1 1.8 0.45 11.5 0.2 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Adeno_E3_CR1 PF02440.15 EGG19563.1 - 0.1 12.4 0.4 0.52 10.1 0.1 2.1 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 MACPF PF01823.19 EGG19564.1 - 3.8e-20 72.9 1.7 3.8e-20 72.9 1.7 2.1 2 0 0 2 2 2 1 MAC/Perforin domain MACPF PF01823.19 EGG19565.1 - 2.9e-22 79.8 1.5 2.9e-22 79.8 1.5 2.6 2 1 1 3 3 3 1 MAC/Perforin domain Menin PF05053.13 EGG19566.1 - 1.3 7.3 10.1 2.1 6.6 10.1 1.3 1 0 0 1 1 1 0 Menin Mito_carr PF00153.27 EGG19567.1 - 3.4e-58 193.6 0.8 2.1e-20 72.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RAP1 PF07218.11 EGG19567.1 - 0.022 13.1 0.0 0.03 12.6 0.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Serine_protease PF18405.1 EGG19567.1 - 0.069 12.3 2.2 7.8 5.6 0.0 3.5 2 1 3 5 5 5 0 Gammaproteobacterial serine protease Proteasome PF00227.26 EGG19568.1 - 3.9e-26 91.7 0.1 4.1e-26 91.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Exonuc_VII_S PF02609.16 EGG19568.1 - 0.056 13.5 0.1 0.091 12.8 0.1 1.3 1 0 0 1 1 1 0 Exonuclease VII small subunit LRR_4 PF12799.7 EGG19569.1 - 0.072 13.5 28.6 0.64 10.5 2.0 6.5 5 1 2 7 7 7 0 Leucine Rich repeats (2 copies) DUF2866 PF11065.8 EGG19569.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) ISP1_C PF18161.1 EGG19569.1 - 1.7 8.6 4.2 5.8 7.0 0.1 3.3 4 0 0 4 4 4 0 ISP1 C-terminal START PF01852.19 EGG19570.1 - 0.0021 17.5 0.1 0.0036 16.7 0.1 1.3 1 0 0 1 1 1 1 START domain WD40 PF00400.32 EGG19571.1 - 1.7e-16 60.3 8.3 0.00032 21.4 0.0 6.6 6 1 1 7 7 7 3 WD domain, G-beta repeat Nup160 PF11715.8 EGG19571.1 - 0.0002 20.2 4.8 0.016 13.9 0.0 3.1 2 1 0 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGG19571.1 - 0.0047 17.2 0.2 1.1 9.6 0.0 4.1 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BSD PF03909.17 EGG19572.1 - 1.9e-06 27.8 0.0 5.7e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 EGG19572.1 - 1.8 8.5 13.7 2.4 8.1 13.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MGC-24 PF05283.11 EGG19572.1 - 2.7 8.4 14.6 2.8 8.4 12.0 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FoP_duplication PF13865.6 EGG19572.1 - 3.5 8.3 7.8 0.43 11.2 1.4 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 MOR2-PAG1_C PF14225.6 EGG19574.1 - 6.7e-13 49.1 2.1 1.9e-12 47.6 2.1 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal RGS PF00615.19 EGG19574.1 - 9.1e-06 25.9 0.2 7.1e-05 23.1 0.0 2.7 3 0 0 3 3 3 1 Regulator of G protein signaling domain TFIIA PF03153.13 EGG19574.1 - 0.45 10.5 47.1 0.2 11.6 11.7 3.7 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Itfg2 PF15907.5 EGG19574.1 - 7.9 5.4 9.0 0.93 8.5 2.0 2.7 3 0 0 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 HEAT_2 PF13646.6 EGG19575.1 - 1.6e-05 25.2 0.1 0.098 13.1 0.0 4.2 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 EGG19575.1 - 0.00016 21.6 0.2 6.1 7.4 0.0 6.3 6 0 0 6 6 6 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EGG19575.1 - 0.00046 20.7 2.5 0.092 13.4 0.1 3.6 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 EGG19575.1 - 0.0088 15.3 0.3 0.0088 15.3 0.3 3.8 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain UBA_e1_thiolCys PF10585.9 EGG19575.1 - 0.085 12.8 1.2 6.1 6.7 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-activating enzyme active site Rit1_C PF17184.4 EGG19575.1 - 0.095 12.1 1.6 0.37 10.2 0.1 2.4 2 0 0 2 2 2 0 Rit1 N-terminal domain Cnd1 PF12717.7 EGG19575.1 - 0.1 12.7 13.9 0.28 11.2 0.5 5.1 4 1 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 HsdM_N PF12161.8 EGG19575.1 - 2.4 8.8 12.4 2.4 8.8 0.1 4.7 4 2 0 4 4 4 0 HsdM N-terminal domain Synaphin PF05835.12 EGG19575.1 - 10 6.4 11.7 12 6.2 3.7 2.9 2 0 0 2 2 2 0 Synaphin protein ATG16 PF08614.11 EGG19576.1 - 0.0032 17.7 13.4 0.0054 17.0 13.4 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EGG19576.1 - 0.14 11.0 17.7 0.24 10.2 17.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein SSP160 PF06933.11 EGG19576.1 - 0.23 9.7 1.3 0.38 8.9 1.2 1.4 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 AAA_23 PF13476.6 EGG19576.1 - 3.5 8.1 20.0 2.1 8.8 17.6 1.8 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.19 EGG19576.1 - 4.3 5.1 14.3 4.8 5.0 14.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 EGG19576.1 - 5.6 6.8 16.7 0.76 9.6 12.3 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Ank_4 PF13637.6 EGG19577.1 - 2.3e-26 91.8 10.2 1.4e-07 31.9 0.0 8.0 5 3 2 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG19577.1 - 1.5e-25 89.5 6.2 1.3e-08 35.2 0.3 5.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG19577.1 - 9.9e-24 83.1 4.9 0.0007 19.8 0.0 9.7 3 2 7 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19577.1 - 6.8e-16 56.8 3.1 2.5 8.9 0.0 11.3 11 1 1 12 12 12 3 Ankyrin repeat DUF3447 PF11929.8 EGG19577.1 - 7.5e-06 25.8 1.7 0.017 15.1 0.0 5.2 3 2 2 5 5 5 2 Domain of unknown function (DUF3447) DUF5049 PF16468.5 EGG19577.1 - 0.0045 16.8 0.4 22 5.0 0.0 5.3 4 1 1 5 5 5 1 Domain of unknown function (DUF5049) SMK-1 PF04802.15 EGG19577.1 - 0.028 14.3 0.6 0.2 11.5 0.0 2.7 3 1 0 3 3 3 0 Component of IIS longevity pathway SMK-1 Ank PF00023.30 EGG19577.1 - 0.068 13.7 0.1 2.9e+02 2.1 0.0 6.2 5 3 0 5 5 5 0 Ankyrin repeat Fibrillarin PF01269.17 EGG19581.1 - 2.5e-100 334.2 0.2 3e-100 334.0 0.2 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EGG19581.1 - 0.0038 16.9 0.0 0.006 16.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 EGG19581.1 - 0.055 13.6 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Carla_C4 PF01623.17 EGG19581.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Na_Ca_ex PF01699.24 EGG19582.1 - 5.7e-17 62.1 33.4 2e-08 34.3 9.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DctQ PF04290.12 EGG19582.1 - 0.019 14.9 0.0 0.019 14.9 0.0 3.0 3 1 1 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF872 PF05915.12 EGG19582.1 - 0.61 10.3 5.2 1.5 9.1 0.0 3.3 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Menin PF05053.13 EGG19582.1 - 0.75 8.1 8.1 1.1 7.6 8.1 1.1 1 0 0 1 1 1 0 Menin GGDEF PF00990.21 EGG19584.1 - 1.9e-27 96.0 0.4 2.3e-27 95.7 0.4 1.1 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Guanylate_cyc PF00211.20 EGG19584.1 - 0.003 17.2 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ank_2 PF12796.7 EGG19586.1 - 2.1e-44 150.0 8.3 5e-11 43.1 0.1 5.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19586.1 - 7.6e-42 141.2 5.3 9.5e-06 26.1 0.0 6.2 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19586.1 - 9.8e-29 96.2 0.0 0.12 13.1 0.0 9.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 EGG19586.1 - 9.3e-26 89.6 6.1 0.027 14.8 0.0 9.6 1 1 9 10 10 10 9 Ankyrin repeats (many copies) DUF5049 PF16468.5 EGG19586.1 - 2.8e-20 72.0 6.1 0.98 9.4 0.0 9.7 2 2 8 10 10 10 7 Domain of unknown function (DUF5049) Ank PF00023.30 EGG19586.1 - 1.1e-13 51.0 0.1 6.3 7.4 0.0 8.9 6 2 2 8 8 8 2 Ankyrin repeat DUF3892 PF13031.6 EGG19586.1 - 9.1e-06 26.2 8.1 1.8 9.2 0.1 4.6 1 1 3 4 4 4 3 Protein of unknown function (DUF3892) DUF5511 PF17630.2 EGG19586.1 - 0.00015 21.9 4.7 7.7 6.8 0.1 5.6 1 1 5 6 6 6 1 Family of unknown function (DUF5511) DUF5099 PF17025.5 EGG19586.1 - 0.068 13.6 0.0 1.4e+02 3.0 0.0 4.1 1 1 3 5 5 5 0 Domain of unknown function (DUF5099) Nucleopor_Nup85 PF07575.13 EGG19586.1 - 0.099 11.2 1.9 14 4.1 0.0 4.1 1 1 4 6 6 6 0 Nup85 Nucleoporin DUF4519 PF15012.6 EGG19588.1 - 0.24 11.6 2.5 0.49 10.6 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) SH3_9 PF14604.6 EGG19589.1 - 7e-08 32.2 0.1 1.1e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGG19589.1 - 1e-07 31.5 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGG19589.1 - 1.8e-07 30.6 0.2 3.2e-07 29.8 0.2 1.5 1 0 0 1 1 1 1 SH3 domain zinc_ribbon_2 PF13240.6 EGG19589.1 - 0.00095 18.8 4.3 0.0024 17.5 4.3 1.7 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EGG19589.1 - 0.0059 16.6 2.3 0.012 15.6 2.3 1.4 1 0 0 1 1 1 1 Double zinc ribbon SOG2 PF10428.9 EGG19589.1 - 0.39 9.9 31.5 0.54 9.4 31.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein zf-C3HC4_3 PF13920.6 EGG19589.1 - 0.46 10.4 2.1 0.69 9.8 2.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_4 PF13717.6 EGG19589.1 - 4 7.4 5.6 0.22 11.4 0.4 1.6 2 0 0 2 2 2 0 zinc-ribbon domain Phosphodiest PF01663.22 EGG19590.1 - 1.1e-72 245.6 0.8 3.2e-37 128.9 0.0 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGG19590.1 - 6.6e-05 22.4 0.1 0.0033 16.9 0.1 2.2 2 0 0 2 2 2 1 Sulfatase DUF229 PF02995.17 EGG19590.1 - 0.0007 18.3 0.1 0.00094 17.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 EGG19590.1 - 0.001 18.5 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 EGG19590.1 - 0.15 12.2 0.3 0.76 9.8 0.5 1.9 2 0 0 2 2 2 0 PglZ domain DUF1501 PF07394.12 EGG19590.1 - 0.21 10.6 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Ribosomal_L44 PF00935.19 EGG19591.1 - 1e-30 106.0 15.5 1e-30 106.0 15.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L44 Tetraspanin PF00335.20 EGG19592.1 - 1.4e-28 100.2 6.8 1.9e-28 99.7 6.8 1.2 1 0 0 1 1 1 1 Tetraspanin family STE3 PF02076.15 EGG19592.1 - 0.026 13.7 2.8 0.056 12.7 2.8 1.5 1 0 0 1 1 1 0 Pheromone A receptor MARVEL PF01284.23 EGG19592.1 - 0.24 11.4 8.7 0.32 11.0 4.4 2.3 2 0 0 2 2 2 0 Membrane-associating domain DUF4131 PF13567.6 EGG19592.1 - 1.4 8.6 7.7 0.5 10.0 3.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) MFS_1 PF07690.16 EGG19592.1 - 1.8 7.4 14.1 0.11 11.4 6.7 2.0 2 0 0 2 2 2 0 Major Facilitator Superfamily EMP70 PF02990.16 EGG19592.1 - 2.4 6.7 11.5 0.1 11.3 5.8 1.5 2 0 0 2 2 2 0 Endomembrane protein 70 zf-C2HC5 PF06221.13 EGG19593.1 - 4e-12 45.9 8.9 4e-12 45.9 8.9 2.2 3 0 0 3 3 3 1 Putative zinc finger motif, C2HC5-type NAGidase PF07555.13 EGG19593.1 - 1.7e-11 44.0 0.5 3.8e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 beta-N-acetylglucosaminidase Sugar_transport PF06800.12 EGG19593.1 - 0.042 13.2 0.4 0.085 12.2 0.4 1.4 1 0 0 1 1 1 0 Sugar transport protein LRR19-TM PF15176.6 EGG19593.1 - 0.16 12.0 1.2 8.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain SKG6 PF08693.10 EGG19593.1 - 0.25 10.8 1.4 0.59 9.6 1.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain T6SS_VipA PF05591.12 EGG19593.1 - 0.26 11.1 2.5 0.47 10.2 0.1 2.4 2 0 0 2 2 2 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 SOG2 PF10428.9 EGG19593.1 - 1.1 8.4 12.5 0.098 11.8 3.2 2.4 2 0 0 2 2 2 0 RAM signalling pathway protein DUF4834 PF16118.5 EGG19594.1 - 0.14 13.1 5.0 0.33 11.9 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Menin PF05053.13 EGG19594.1 - 0.17 10.2 7.2 0.25 9.6 7.2 1.2 1 0 0 1 1 1 0 Menin DDE_1 PF03184.19 EGG19595.1 - 1e-08 35.1 0.4 2.2e-08 33.9 0.4 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease LRR_8 PF13855.6 EGG19595.1 - 0.00034 20.3 0.3 0.038 13.8 0.1 3.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EGG19595.1 - 0.051 14.0 4.7 22 5.6 0.1 5.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Tir_receptor_C PF07489.11 EGG19595.1 - 0.22 11.5 3.3 0.38 10.7 3.3 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus EGF_2 PF07974.13 EGG19596.1 - 0.91 9.9 30.2 0.83 10.1 10.3 2.6 2 0 0 2 2 2 0 EGF-like domain PAP2 PF01569.21 EGG19597.1 - 0.00077 19.2 8.8 0.0016 18.2 2.2 2.8 1 1 1 2 2 2 1 PAP2 superfamily Wzy_C PF04932.15 EGG19597.1 - 7.4 6.2 10.5 60 3.2 10.6 2.0 1 1 0 1 1 1 0 O-Antigen ligase CPBP PF02517.16 EGG19597.1 - 7.9 6.9 9.3 1.2 9.5 1.1 2.3 1 1 1 2 2 2 0 CPBP intramembrane metalloprotease PHR PF08005.12 EGG19598.1 - 6.4e-12 46.4 1.7 2.8e-11 44.3 0.0 3.2 2 0 0 2 2 2 1 PHR domain zf-RING_2 PF13639.6 EGG19598.1 - 5.2e-08 33.1 4.8 5.2e-08 33.1 4.8 4.4 4 0 0 4 4 4 1 Ring finger domain ANAPC10 PF03256.16 EGG19598.1 - 5e-05 23.0 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) zf-A20 PF01754.16 EGG19599.1 - 7.4e-08 32.2 6.1 7.4e-08 32.2 6.1 2.6 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 EGG19599.1 - 3.1e-06 27.2 6.6 3.1e-06 27.2 6.6 1.8 2 0 0 2 2 2 1 AN1-like Zinc finger DUF3439 PF11921.8 EGG19599.1 - 0.0068 16.4 13.3 0.0068 16.4 13.3 4.2 3 1 1 4 4 4 2 Domain of unknown function (DUF3439) Epimerase PF01370.21 EGG19600.1 - 8.5e-25 87.6 0.1 1.1e-24 87.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG19600.1 - 5.5e-15 55.1 0.1 7.2e-15 54.7 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGG19600.1 - 5.3e-14 52.4 0.1 6.2e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGG19600.1 - 2.9e-12 46.3 0.1 1.4e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EGG19600.1 - 2.6e-09 37.2 0.0 5.6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGG19600.1 - 8e-08 32.1 0.1 3.5e-06 26.8 0.2 2.2 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 EGG19600.1 - 5.7e-05 22.4 1.8 0.00015 21.0 1.8 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGG19600.1 - 0.0043 16.2 0.2 0.0068 15.6 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pecanex_C PF05041.15 EGG19600.1 - 0.034 13.7 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Pecanex protein (C-terminus) adh_short PF00106.25 EGG19600.1 - 0.038 13.5 0.0 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Lysyl_oxidase PF01186.17 EGG19601.1 - 0.12 12.0 0.3 0.21 11.2 0.0 1.5 2 0 0 2 2 2 0 Lysyl oxidase Cnd3 PF12719.7 EGG19602.1 - 2.1e-12 46.9 3.6 3.4e-11 42.9 3.5 3.1 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 EGG19602.1 - 2.1e-05 24.4 0.1 0.76 10.2 0.0 5.6 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 EGG19602.1 - 0.0053 17.1 0.0 12 6.3 0.0 3.8 3 1 1 4 4 4 3 HEAT repeats DUF3439 PF11921.8 EGG19602.1 - 0.61 10.1 4.4 2.2 8.3 4.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sel1 PF08238.12 EGG19604.1 - 3.3e-09 37.1 1.0 0.0096 16.6 0.0 4.8 4 1 0 4 4 4 2 Sel1 repeat TPR_2 PF07719.17 EGG19604.1 - 9.1e-05 22.3 2.1 0.14 12.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG19604.1 - 0.00041 20.2 0.0 0.04 13.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG19604.1 - 0.00089 19.4 3.5 0.0012 19.0 0.2 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EGG19604.1 - 0.0027 17.4 4.5 2.2 8.2 0.8 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG19604.1 - 0.0035 17.4 12.9 0.88 9.9 0.5 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG19604.1 - 0.0045 17.5 0.1 8.8 7.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG19604.1 - 0.024 15.1 0.0 0.047 14.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2203 PF09969.9 EGG19608.1 - 0.0043 17.8 1.3 7.3 7.3 0.1 3.3 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2203) Ribonuc_red_2_N PF08471.10 EGG19608.1 - 0.028 14.6 0.3 15 5.8 0.0 2.7 2 0 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase zf-C2H2_4 PF13894.6 EGG19608.1 - 0.035 14.9 5.7 5.1 8.2 0.5 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Pex26 PF07163.12 EGG19608.1 - 0.087 12.1 0.4 16 4.7 0.0 2.5 2 0 0 2 2 2 0 Pex26 protein Rad50_zn_hook PF04423.14 EGG19608.1 - 0.12 12.2 4.3 8.1 6.4 0.3 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 EGG19608.1 - 0.31 10.9 4.6 12 5.8 0.4 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF4834 PF16118.5 EGG19608.1 - 0.37 11.8 23.6 0.34 11.9 4.2 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) Prothymosin PF03247.14 EGG19608.1 - 1.1 9.8 36.2 4.8 7.7 13.8 2.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family CobT PF06213.12 EGG19608.1 - 1.9 7.8 6.5 9.7 5.5 0.5 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT FSIP1 PF15554.6 EGG19608.1 - 3.3 6.7 25.1 3.9 6.5 8.3 2.2 2 0 0 2 2 2 0 FSIP1 family zf_C2H2_10 PF18414.1 EGG19608.1 - 4.3 7.0 11.2 12 5.6 2.0 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger Menin PF05053.13 EGG19608.1 - 8.5 4.6 23.9 3.6 5.8 7.1 2.1 2 0 0 2 2 2 0 Menin Secretin_N_2 PF07655.13 EGG19608.1 - 9.6 6.8 43.8 2.5 8.7 14.7 3.4 3 0 0 3 3 3 0 Secretin N-terminal domain FTH PF01827.27 EGG19609.1 - 0.036 13.9 0.2 0.063 13.1 0.2 1.4 1 0 0 1 1 1 0 FTH domain FNIP PF05725.12 EGG19610.1 - 0.0008 19.5 31.3 0.61 10.3 0.1 8.4 7 2 3 10 10 10 6 FNIP Repeat SOCS_box PF07525.16 EGG19610.1 - 0.0066 16.8 5.1 7.7 7.0 0.0 5.1 4 1 0 4 4 4 2 SOCS box SAP130_C PF16014.5 EGG19611.1 - 5.6 5.9 10.3 6 5.8 10.3 1.0 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Clostridium_P47 PF06597.11 EGG19611.1 - 7.5 5.2 14.2 7.6 5.1 14.2 1.2 1 0 0 1 1 1 0 Clostridium P-47 protein EMG1 PF03587.14 EGG19612.1 - 0.087 12.5 0.1 0.23 11.1 0.1 1.8 1 1 0 1 1 1 0 EMG1/NEP1 methyltransferase ELFV_dehydrog PF00208.21 EGG19619.1 - 5.6e-54 183.4 0.0 8.9e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EGG19619.1 - 3.9e-22 77.8 0.2 7.7e-14 50.3 0.1 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EGG19619.1 - 0.049 13.5 0.0 0.23 11.3 0.0 2.1 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain EcoEI_R_C PF08463.10 EGG19619.1 - 0.13 12.4 1.2 2.5 8.2 0.1 2.6 2 0 0 2 2 2 0 EcoEI R protein C-terminal RRM_1 PF00076.22 EGG19620.1 - 1.6e-16 59.9 0.3 2.5e-16 59.3 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGG19620.1 - 3.7e-12 45.7 13.7 5.7e-07 29.3 3.7 2.4 2 0 0 2 2 2 2 Zinc knuckle Limkain-b1 PF11608.8 EGG19620.1 - 0.0021 18.1 0.1 0.0046 17.0 0.1 1.5 1 0 0 1 1 1 1 Limkain b1 zf-CCHC_4 PF14392.6 EGG19620.1 - 0.014 15.1 6.3 0.57 10.0 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGG19620.1 - 0.042 13.8 3.6 2.8 8.0 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle RRM_5 PF13893.6 EGG19620.1 - 0.099 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaJ_CXXCXGXG PF00684.19 EGG19620.1 - 0.28 11.6 7.2 7.6 7.0 7.3 2.4 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC_5 PF14787.6 EGG19620.1 - 0.35 10.6 12.2 2.5 7.9 3.3 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EGG19620.1 - 0.84 9.5 6.8 0.62 9.9 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 EGG19620.1 - 4.3 7.7 6.0 1.5 9.2 1.0 2.3 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G tRNA_SAD PF07973.14 EGG19621.1 - 0.026 14.6 0.1 1.8 8.7 0.1 2.8 2 0 0 2 2 2 0 Threonyl and Alanyl tRNA synthetase second additional domain Dicty_CAR PF05462.11 EGG19622.1 - 2.5e-126 420.9 31.6 4.1e-126 420.2 31.6 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 EGG19622.1 - 6e-07 29.0 28.5 6e-07 29.0 28.5 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) FNIP PF05725.12 EGG19623.1 - 8.9e-37 125.0 18.3 1.4e-13 50.7 0.5 4.8 4 1 0 4 4 4 4 FNIP Repeat Pkinase PF00069.25 EGG19623.1 - 1.3e-14 54.2 0.2 9.4e-07 28.5 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19623.1 - 0.0072 15.6 0.1 0.06 12.6 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase MAP65_ASE1 PF03999.12 EGG19624.1 - 6e-36 124.3 14.2 6e-36 124.3 14.2 3.1 1 1 2 3 3 3 1 Microtubule associated protein (MAP65/ASE1 family) CtIP_N PF10482.9 EGG19624.1 - 0.7 10.0 9.3 1.1 9.3 4.3 2.8 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DBR1 PF05011.13 EGG19625.1 - 1.4e-20 74.1 0.7 1.4e-20 74.1 0.7 1.6 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Menin PF05053.13 EGG19625.1 - 0.0091 14.4 1.7 0.013 13.9 1.7 1.2 1 0 0 1 1 1 1 Menin Metallophos_2 PF12850.7 EGG19625.1 - 0.046 13.9 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF16 PF01519.16 EGG19626.1 - 0.012 16.1 24.7 0.46 11.0 5.9 3.7 1 1 3 4 4 4 0 Protein of unknown function DUF16 CLZ PF16526.5 EGG19626.1 - 0.017 15.4 1.1 0.06 13.7 1.1 2.0 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CdiI_N PF18228.1 EGG19626.1 - 0.026 14.3 7.0 1.8 8.4 0.2 3.9 4 0 0 4 4 4 0 CdiI N-terminal domain DUF5395 PF17373.2 EGG19626.1 - 0.11 13.2 1.6 34 5.2 0.0 3.5 2 1 1 3 3 3 0 Family of unknown function (DUF5395) SWIRM-assoc_1 PF16495.5 EGG19626.1 - 0.12 12.3 5.5 1.3 9.0 0.2 3.6 2 2 2 4 4 4 0 SWIRM-associated region 1 UPF0242 PF06785.11 EGG19626.1 - 0.12 12.4 17.2 5.6 7.0 0.2 3.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 EGG19626.1 - 0.33 11.6 17.3 0.38 11.4 1.9 4.0 2 1 3 5 5 5 0 SlyX FAM76 PF16046.5 EGG19626.1 - 0.47 9.8 15.4 6.9 5.9 15.4 2.1 1 1 0 1 1 1 0 FAM76 protein TMF_DNA_bd PF12329.8 EGG19626.1 - 0.66 10.0 13.2 7.4 6.7 0.1 3.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc29 PF17082.5 EGG19626.1 - 0.82 9.5 6.6 0.68 9.7 3.4 2.1 1 1 1 2 2 2 0 Spindle Pole Component 29 Cupin_2 PF07883.11 EGG19627.1 - 1.4e-05 24.7 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain 3-HAO PF06052.12 EGG19627.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Cupin_3 PF05899.12 EGG19627.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Hemerythrin PF01814.23 EGG19628.1 - 2.3e-08 34.7 0.7 1.9e-07 31.8 0.7 2.0 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Imm6 PF14434.6 EGG19628.1 - 0.05 13.5 0.1 0.088 12.7 0.1 1.4 1 0 0 1 1 1 0 Immunity protein Imm6 DUF1966 PF09260.11 EGG19630.1 - 0.12 12.7 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) SdrD_B PF17210.3 EGG19631.1 - 0 3333.7 275.2 3.4e-23 82.0 0.8 59.9 59 1 0 59 59 59 59 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG19631.1 - 0 1374.6 169.6 1.1e-09 38.4 0.2 60.8 59 2 0 59 59 59 57 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EGG19631.1 - 3.8e-178 578.3 139.5 0.00025 21.3 0.1 55.5 56 1 1 57 57 56 46 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 EGG19631.1 - 3.8e-150 488.3 100.6 0.0018 18.3 0.3 55.4 57 0 0 57 57 55 36 CarboxypepD_reg-like domain bMG3 PF11974.8 EGG19631.1 - 1.8e-119 390.9 11.4 0.0043 17.1 0.0 48.3 51 0 0 51 51 50 24 Bacterial alpha-2-macroglobulin MG3 domain Big_1 PF02369.16 EGG19631.1 - 7e-91 298.2 202.3 0.0093 15.9 1.7 52.8 56 0 0 56 56 54 30 Bacterial Ig-like domain (group 1) DUF2012 PF09430.10 EGG19631.1 - 7.6e-77 255.4 27.7 0.1 12.7 0.0 45.3 50 0 0 50 50 48 9 Protein of unknown function (DUF2012) MetallophosN PF16371.5 EGG19631.1 - 1e-67 224.3 140.9 0.0062 16.8 0.3 50.1 51 0 0 51 51 51 18 N terminal of Calcineurin-like phosphoesterase Big_6 PF17936.1 EGG19631.1 - 4.3e-20 71.8 62.3 6.6 7.1 0.1 30.4 35 0 0 35 35 32 3 Bacterial Ig domain MG4 PF17789.1 EGG19631.1 - 3e-19 69.0 62.5 10 6.4 0.0 32.6 37 0 0 37 37 32 0 Macroglobulin domain MG4 DUF2606 PF10794.9 EGG19631.1 - 7.4e-19 67.8 4.1 2.7 7.7 0.0 19.7 23 0 0 23 23 21 2 Protein of unknown function (DUF2606) Dioxygenase_C PF00775.21 EGG19631.1 - 1.8e-18 66.6 61.0 4 6.8 0.0 34.5 43 0 0 43 43 41 2 Dioxygenase TTR-52 PF01060.23 EGG19631.1 - 7.6e-17 61.8 35.8 12 6.7 0.0 28.2 38 0 0 38 38 29 0 Transthyretin-like family Y_Y_Y PF07495.13 EGG19631.1 - 1.7e-14 53.5 64.0 6 6.9 0.0 31.6 39 0 0 39 39 35 1 Y_Y_Y domain Invasin_D3 PF09134.10 EGG19631.1 - 5.1e-07 29.9 122.8 3.9 7.9 0.0 35.1 42 0 0 42 42 41 3 Invasin, domain 3 EMP24_GP25L PF01105.24 EGG19631.1 - 1.3e-06 28.5 32.2 4.1 7.3 0.0 19.9 24 3 4 28 28 25 1 emp24/gp25L/p24 family/GOLD phage_tail_N PF08400.10 EGG19631.1 - 8.9e-05 22.5 72.9 0.17 11.9 0.0 28.2 39 0 0 39 39 34 1 Prophage tail fibre N-terminal DUF4295 PF14128.6 EGG19631.1 - 0.0082 15.9 5.7 84 3.1 0.0 9.3 12 0 0 12 12 11 0 Domain of unknown function (DUF4295) DUF229 PF02995.17 EGG19631.1 - 0.05 12.2 0.0 44 2.5 0.0 4.7 7 0 0 7 7 7 0 Protein of unknown function (DUF229) DUF824 PF05688.11 EGG19631.1 - 0.086 12.7 25.0 0.76 9.7 0.0 14.3 21 0 0 21 21 17 0 Salmonella repeat of unknown function (DUF824) EF-hand_1 PF00036.32 EGG19631.1 - 0.092 12.3 1.4 8.5 6.2 0.1 5.1 3 0 0 3 3 3 0 EF hand DUF188 PF02639.14 EGG19631.1 - 0.25 11.0 0.7 23 4.6 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized BCR, YaiI/YqxD family COG1671 UbiA PF01040.18 EGG19632.1 - 7.1e-15 55.0 8.1 8.7e-15 54.7 8.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RhoGAP PF00620.27 EGG19633.1 - 1.5e-41 141.7 0.2 1.5e-41 141.7 0.2 3.7 4 1 1 5 5 5 1 RhoGAP domain Oxysterol_BP PF01237.18 EGG19635.1 - 4.8e-50 170.5 11.2 1.2e-47 162.5 11.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF1084 PF06454.11 EGG19636.1 - 9.4e-13 48.2 15.4 1.2e-12 47.8 15.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) RNA_pol_Rpb1_5 PF04998.17 EGG19637.1 - 4.1e-89 298.5 6.0 4.1e-89 298.5 6.0 2.5 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGG19637.1 - 1.5e-62 210.7 0.0 3e-62 209.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGG19637.1 - 5.1e-33 114.2 0.0 1.4e-32 112.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EGG19637.1 - 6.6e-32 111.1 0.3 6.6e-32 111.1 0.3 2.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EGG19637.1 - 1.8e-21 76.1 0.0 1.8e-21 76.1 0.0 3.4 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.12 EGG19637.1 - 1.9 6.6 54.3 0.081 11.1 46.0 2.3 2 0 0 2 2 2 0 Nop14-like family TFIIIC_delta PF12657.7 EGG19638.1 - 0.0017 18.3 1.7 0.019 14.9 0.0 2.9 2 1 1 3 3 3 1 Transcription factor IIIC subunit delta N-term Topoisom_bac PF01131.20 EGG19640.1 - 2e-97 326.9 0.0 3.7e-97 325.9 0.0 1.5 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EGG19640.1 - 9.1e-18 64.4 0.0 1.9e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain RNA_POL_M_15KD PF02150.16 EGG19640.1 - 3.2 7.7 10.6 0.47 10.4 4.0 2.8 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Cnn_1N PF07989.11 EGG19641.1 - 3.3e-06 27.2 2.3 3.3e-06 27.2 2.3 13.7 2 1 9 11 11 11 2 Centrosomin N-terminal motif 1 DUF5082 PF16888.5 EGG19641.1 - 5.9e-05 23.3 36.7 0.00021 21.6 20.0 9.7 4 3 5 9 9 9 2 Domain of unknown function (DUF5082) DUF3584 PF12128.8 EGG19641.1 - 0.0003 18.5 90.3 0.0003 18.5 90.3 3.6 1 1 2 3 3 3 1 Protein of unknown function (DUF3584) ERM PF00769.19 EGG19641.1 - 0.0011 18.8 38.9 0.0011 18.8 38.9 7.1 1 1 4 5 5 5 2 Ezrin/radixin/moesin family Fib_alpha PF08702.10 EGG19641.1 - 0.0061 16.7 9.8 0.0061 16.7 9.8 9.3 3 2 5 9 9 9 2 Fibrinogen alpha/beta chain family DDT PF02791.17 EGG19642.1 - 2.3e-05 24.6 0.0 5.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EGG19642.1 - 0.0022 17.5 0.1 0.0059 16.1 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WSD PF15613.6 EGG19642.1 - 0.081 13.4 0.1 0.081 13.4 0.1 3.0 2 1 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif SdrD_B PF17210.3 EGG19643.1 - 3.1e-52 175.5 55.6 1.4e-08 34.9 0.3 13.2 14 0 0 14 14 13 10 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG19643.1 - 7e-45 151.2 31.6 2.9e-11 43.5 0.5 8.7 8 0 0 8 8 8 4 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EGG19643.1 - 7.3e-20 70.8 4.3 0.00027 20.9 0.0 4.8 4 0 0 4 4 4 4 CarboxypepD_reg-like domain SpaA PF17802.1 EGG19643.1 - 2.2e-17 63.1 29.0 0.0071 16.7 0.0 9.0 9 0 0 9 9 8 6 Prealbumin-like fold domain DUF4198 PF10670.9 EGG19643.1 - 4.3e-13 50.1 0.0 0.035 14.5 0.0 5.4 5 0 0 5 5 5 4 Domain of unknown function (DUF4198) Big_1 PF02369.16 EGG19643.1 - 1.4e-10 41.0 44.3 5.1e-06 26.4 0.4 8.2 9 0 0 9 9 9 4 Bacterial Ig-like domain (group 1) Dioxygenase_C PF00775.21 EGG19643.1 - 5.2e-08 32.5 7.6 0.87 9.0 0.0 6.8 5 4 1 6 6 6 4 Dioxygenase Invasin_D3 PF09134.10 EGG19643.1 - 1.5e-06 28.4 3.8 0.0024 18.2 0.4 5.3 4 0 0 4 4 4 1 Invasin, domain 3 DUF2012 PF09430.10 EGG19643.1 - 2.2e-06 27.8 0.1 0.86 9.7 0.0 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF2012) fn3_3 PF14686.6 EGG19643.1 - 8.8e-06 25.4 17.2 1.1 9.0 0.3 5.5 5 0 0 5 5 5 4 Polysaccharide lyase family 4, domain II NAD_binding_8 PF13450.6 EGG19643.1 - 5e-05 23.4 0.0 5.4 7.3 0.0 5.2 6 0 0 6 6 6 1 NAD(P)-binding Rossmann-like domain TTR-52 PF01060.23 EGG19643.1 - 0.00011 22.8 1.1 12 6.6 0.0 7.1 8 0 0 8 8 8 0 Transthyretin-like family PrmA PF06325.13 EGG19643.1 - 0.0073 15.7 0.4 1.4 8.2 0.0 3.4 4 0 0 4 4 4 1 Ribosomal protein L11 methyltransferase (PrmA) Y_Y_Y PF07495.13 EGG19643.1 - 0.14 12.2 22.0 0.78 9.7 0.1 6.2 6 1 1 7 7 7 0 Y_Y_Y domain EF-hand_1 PF00036.32 EGG19643.1 - 0.81 9.4 2.6 8.5 6.2 0.3 3.3 2 0 0 2 2 2 0 EF hand BNIP3 PF06553.12 EGG19643.1 - 1 9.0 5.3 8.4 6.0 0.1 3.7 4 0 0 4 4 4 0 BNIP3 NAD_binding_5 PF07994.12 EGG19644.1 - 4.4e-143 476.5 0.0 5.8e-143 476.1 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EGG19644.1 - 1.5e-47 160.3 0.3 3.5e-47 159.2 0.3 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF5052 PF16475.5 EGG19644.1 - 0.029 14.0 2.5 0.034 13.8 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5052) Pro_isomerase PF00160.21 EGG19645.1 - 2e-68 229.6 0.9 2.4e-45 154.6 0.2 2.0 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S19e PF01090.19 EGG19646.1 - 1.6e-52 176.8 0.0 1.8e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L21e PF01157.18 EGG19647.1 - 1.1e-42 143.9 2.0 1.5e-42 143.5 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e DUF4690 PF15756.5 EGG19648.1 - 0.034 14.8 0.7 0.12 13.0 0.0 2.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Caldesmon PF02029.15 EGG19649.1 - 0.02 13.7 13.3 0.026 13.3 13.3 1.1 1 0 0 1 1 1 0 Caldesmon Asp-B-Hydro_N PF05279.11 EGG19649.1 - 0.28 11.2 15.1 0.44 10.6 15.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ndc1_Nup PF09531.10 EGG19649.1 - 0.82 8.3 5.9 1.1 7.9 5.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_L5_C PF00673.21 EGG19651.1 - 5.4e-21 74.6 0.0 7.7e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGG19651.1 - 3.8e-20 72.0 0.0 8.6e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 Rogdi_lz PF10259.9 EGG19652.1 - 1.7e-12 47.4 14.3 2.5e-08 33.7 9.7 3.3 2 1 0 2 2 2 2 Rogdi leucine zipper containing protein Presenilin PF01080.17 EGG19652.1 - 4 6.1 25.0 0.094 11.5 14.6 2.2 2 0 0 2 2 2 0 Presenilin ALMT PF11744.8 EGG19652.1 - 6.3 5.5 16.2 0.63 8.8 10.4 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter DDHD PF02862.17 EGG19652.1 - 6.7 6.8 19.9 2.3 8.3 12.9 2.5 2 0 0 2 2 2 0 DDHD domain MOSC_N PF03476.16 EGG19654.1 - 2.5e-29 101.6 0.1 2.6e-28 98.3 0.0 2.3 2 1 1 3 3 3 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EGG19654.1 - 1.8e-19 70.1 0.0 3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 MOSC domain Med7 PF05983.11 EGG19655.1 - 7.5e-55 186.0 0.2 7.5e-55 186.0 0.2 2.5 3 0 0 3 3 3 1 MED7 protein ThylakoidFormat PF11264.8 EGG19655.1 - 0.029 14.1 0.5 0.029 14.1 0.5 1.7 1 1 0 2 2 2 0 Thylakoid formation protein ParE-like_toxin PF15781.5 EGG19655.1 - 0.059 13.3 0.2 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 ParE-like toxin of type II bacterial toxin-antitoxin system SPC25 PF06703.11 EGG19655.1 - 0.066 13.0 2.2 1.3 8.8 0.0 2.3 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CCDC53 PF10152.9 EGG19655.1 - 0.15 12.4 9.4 0.1 13.0 7.1 1.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Suf PF05843.14 EGG19655.1 - 0.43 10.5 9.9 0.66 9.9 9.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) YlbD_coat PF14071.6 EGG19655.1 - 0.66 10.2 7.9 0.98 9.7 1.9 2.4 2 0 0 2 2 2 0 Putative coat protein RP-C_C PF11800.8 EGG19655.1 - 1.4 9.0 5.8 2.2 8.3 5.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Hydin_ADK PF17213.3 EGG19655.1 - 4.1 7.6 6.3 4 7.7 3.2 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain PPTA PF01239.22 EGG19656.1 - 9.4e-39 130.1 21.2 1.9e-08 33.7 0.0 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_1 PF00515.28 EGG19657.1 - 2.1e-30 103.3 10.5 4.6e-05 23.1 0.3 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGG19657.1 - 1.5e-25 87.2 6.2 0.00015 21.6 0.0 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGG19657.1 - 1.1e-17 62.6 9.2 0.00013 21.8 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGG19657.1 - 2.6e-12 46.9 6.9 0.00034 20.8 0.2 4.8 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGG19657.1 - 7.6e-12 44.7 3.2 2.4 8.7 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGG19657.1 - 2.3e-10 40.8 0.1 0.0065 17.0 0.0 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG19657.1 - 5.7e-10 39.7 0.0 2.5e-05 24.8 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG19657.1 - 6e-10 39.1 6.2 0.005 17.4 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG19657.1 - 1.6e-08 34.7 0.0 1 10.4 0.0 5.0 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 EGG19657.1 - 3.5e-07 29.7 0.1 0.0029 16.9 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG19657.1 - 4.3e-06 26.4 0.4 0.12 12.5 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG19657.1 - 4.1e-05 23.7 3.9 0.0028 17.8 0.7 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGG19657.1 - 4.9e-05 23.4 0.0 0.09 12.9 0.0 3.9 1 1 4 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGG19657.1 - 0.00079 19.1 7.9 0.91 9.3 0.1 5.2 2 1 3 5 5 5 1 TPR repeat TPR_MalT PF17874.1 EGG19657.1 - 0.11 11.9 0.1 2.8 7.2 0.3 2.2 1 1 0 2 2 2 0 MalT-like TPR region RasGEF PF00617.19 EGG19659.1 - 5.4e-55 186.3 0.0 1.8e-54 184.6 0.0 2.0 1 0 0 1 1 1 1 RasGEF domain FERM_f0 PF16511.5 EGG19659.1 - 2.2e-10 40.7 0.8 1.7e-05 25.0 0.0 4.1 3 0 0 3 3 3 2 N-terminal or F0 domain of Talin-head FERM DDE_Tnp_4 PF13359.6 EGG19659.1 - 4.3e-09 36.2 0.5 2.4e-08 33.8 0.0 2.6 2 0 0 2 2 2 1 DDE superfamily endonuclease RasGEF_N PF00618.20 EGG19659.1 - 0.0001 22.5 0.4 0.0001 22.5 0.4 5.2 6 0 0 6 6 6 1 RasGEF N-terminal motif RA PF00788.23 EGG19659.1 - 0.0085 16.7 0.2 0.37 11.4 0.0 3.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain YukD PF08817.10 EGG19659.1 - 0.042 14.5 0.0 7.3 7.4 0.0 2.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD FERM_N PF09379.10 EGG19659.1 - 0.058 13.4 0.3 9 6.3 0.0 2.8 2 0 0 2 2 2 0 FERM N-terminal domain PQ-loop PF04193.14 EGG19660.1 - 4e-26 90.5 10.6 3.5e-15 55.5 4.6 3.0 4 0 0 4 4 4 2 PQ loop repeat Polysacc_synt_C PF14667.6 EGG19660.1 - 0.002 18.2 16.3 0.0036 17.4 6.6 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis C-terminal domain DUF4131 PF13567.6 EGG19660.1 - 0.37 10.4 1.7 0.84 9.3 1.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1282 PF06930.12 EGG19660.1 - 1 9.1 10.2 4.7 6.9 10.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) MtN3_slv PF03083.16 EGG19660.1 - 8.2 6.5 16.0 4.8 7.3 2.0 3.5 3 2 0 3 3 3 0 Sugar efflux transporter for intercellular exchange UDG PF03167.19 EGG19662.1 - 9.3e-07 29.0 4.4 0.0021 18.0 0.0 2.9 2 1 1 3 3 3 2 Uracil DNA glycosylase superfamily DHR-2 PF06920.13 EGG19663.1 - 4.7e-63 213.6 3.6 6.1e-63 213.2 3.6 1.0 1 0 0 1 1 1 1 Dock homology region 2 Plk4_PB1 PF18190.1 EGG19663.1 - 0.087 13.0 0.2 2.9 8.1 0.1 2.5 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 MRP-63 PF14978.6 EGG19663.1 - 0.47 11.1 3.2 4.3 8.0 0.2 3.3 2 2 0 2 2 2 0 Mitochondrial ribosome protein 63 DUF16 PF01519.16 EGG19663.1 - 1.2 9.7 4.5 6 7.4 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 DOCK_N PF16172.5 EGG19664.1 - 3.5e-46 157.8 3.2 7.7e-36 123.8 0.1 2.7 3 0 0 3 3 3 2 DOCK N-terminus DOCK-C2 PF14429.6 EGG19664.1 - 1e-31 110.3 0.0 3.2e-31 108.7 0.0 1.9 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 EGG19664.1 - 0.00044 20.1 0.1 0.0058 16.5 0.1 2.4 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGG19664.1 - 0.0057 16.2 0.0 2.2 8.0 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGG19664.1 - 0.11 12.1 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain DUF5502 PF17606.2 EGG19664.1 - 0.16 12.7 0.4 4.6 8.0 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5502) VKG_Carbox PF05090.14 EGG19666.1 - 1.7e-11 43.6 24.0 1.7e-11 43.6 24.0 1.7 2 0 0 2 2 2 1 Vitamin K-dependent gamma-carboxylase PPR_3 PF13812.6 EGG19667.1 - 4.9e-06 26.5 0.3 1.9e-05 24.7 0.2 2.1 1 1 1 2 2 2 1 Pentatricopeptide repeat domain TipAS PF07739.13 EGG19667.1 - 0.11 13.0 1.5 3.3 8.3 0.5 2.5 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain Peptidase_U32 PF01136.19 EGG19667.1 - 0.18 10.9 3.4 0.25 10.5 0.1 2.3 1 1 1 2 2 2 0 Peptidase family U32 Far-17a_AIG1 PF04750.14 EGG19667.1 - 0.29 10.4 1.2 0.31 10.3 0.1 1.6 2 0 0 2 2 2 0 FAR-17a/AIG1-like protein IlvC PF01450.19 EGG19667.1 - 1.6 9.0 6.2 0.47 10.7 2.2 2.2 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain EGF_2 PF07974.13 EGG19668.1 - 6e-05 23.3 12.9 0.00015 22.1 12.9 1.7 1 0 0 1 1 1 1 EGF-like domain LRR_8 PF13855.6 EGG19668.1 - 0.00012 21.8 5.4 0.023 14.5 0.4 4.7 4 1 0 4 4 4 2 Leucine rich repeat DUF3844 PF12955.7 EGG19668.1 - 0.0002 21.5 2.6 0.0019 18.3 0.2 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) EB PF01683.18 EGG19668.1 - 0.0027 18.0 3.3 0.0068 16.7 3.3 1.6 1 0 0 1 1 1 1 EB module EGF PF00008.27 EGG19668.1 - 0.011 16.0 5.5 0.029 14.7 5.5 1.7 1 0 0 1 1 1 0 EGF-like domain I-EGF_1 PF18372.1 EGG19668.1 - 0.026 14.6 9.1 0.059 13.5 9.1 1.6 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 G8 PF10162.9 EGG19668.1 - 0.034 14.2 0.1 0.13 12.4 0.1 2.0 1 0 0 1 1 1 0 G8 domain hEGF PF12661.7 EGG19668.1 - 0.49 11.1 12.2 0.11 13.1 8.0 2.3 2 0 0 2 2 1 0 Human growth factor-like EGF GLEYA PF10528.9 EGG19668.1 - 0.5 10.8 7.0 7.6 7.0 0.1 3.6 3 0 0 3 3 3 0 GLEYA domain EGF_Tenascin PF18720.1 EGG19668.1 - 1.2 9.3 8.1 3.1 7.9 8.1 1.7 1 0 0 1 1 1 0 Tenascin EGF domain LRR_4 PF12799.7 EGG19668.1 - 6.3 7.4 31.1 0.23 11.9 2.1 7.2 7 3 3 10 10 9 0 Leucine Rich repeats (2 copies) RapA_C PF12137.8 EGG19672.1 - 0.096 11.7 0.5 0.14 11.1 0.5 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Fis1_TPR_N PF14852.6 EGG19672.1 - 0.48 10.2 4.4 3.2 7.5 0.1 2.9 3 0 0 3 3 3 0 Fis1 N-terminal tetratricopeptide repeat DnaB_2 PF07261.11 EGG19673.1 - 0.015 15.0 0.2 0.068 12.9 0.0 2.1 2 0 0 2 2 2 0 Replication initiation and membrane attachment DUF3553 PF12073.8 EGG19676.1 - 0.018 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) VPR PF00522.18 EGG19677.1 - 0.26 11.3 1.6 1.1 9.4 0.5 2.0 1 1 1 2 2 2 0 VPR/VPX protein ATP-synt_F PF01990.17 EGG19679.1 - 0.0092 16.3 0.0 0.032 14.5 0.0 1.9 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Endotoxin_N PF03945.14 EGG19681.1 - 3.9e-45 154.3 4.1 6.4e-45 153.6 4.1 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain CDC45 PF02724.14 EGG19682.1 - 0.047 12.0 41.5 0.21 9.8 27.3 2.1 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 EGG19682.1 - 0.071 12.5 44.1 0.34 10.3 28.4 2.2 2 0 0 2 2 2 0 SDA1 DUF2052 PF09747.9 EGG19682.1 - 0.073 13.2 36.5 0.45 10.6 19.7 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 EGG19682.1 - 0.17 10.0 47.5 0.41 8.8 30.5 2.1 2 0 0 2 2 2 0 Nop14-like family PTPRCAP PF15713.5 EGG19682.1 - 3.2 8.1 32.8 4 7.7 5.6 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Spt5_N PF11942.8 EGG19682.1 - 4 8.5 35.3 11 7.1 6.1 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal YL1 PF05764.13 EGG19682.1 - 7.7 6.6 64.3 2.9 7.9 44.5 2.6 1 1 1 2 2 2 0 YL1 nuclear protein Histone_H2A_C PF16211.5 EGG19683.1 - 1.2e-13 50.5 0.6 3.6e-13 49.0 0.6 1.9 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGG19683.1 - 1.6e-11 44.7 0.2 2.3e-11 44.2 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGG19683.1 - 1.2e-05 25.4 0.0 2.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ank_2 PF12796.7 EGG19684.1 - 0.0072 16.9 0.0 0.022 15.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG19684.1 - 0.013 16.0 0.0 12 6.8 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeat DUF3447 PF11929.8 EGG19684.1 - 0.018 15.0 0.8 0.2 11.6 0.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3447) TIG PF01833.24 EGG19687.1 - 1.1e-15 57.4 56.6 6.5e-08 32.5 8.3 8.7 9 0 0 9 9 9 6 IPT/TIG domain EGF_2 PF07974.13 EGG19687.1 - 0.0058 17.0 15.0 0.013 15.9 15.0 1.6 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 EGG19687.1 - 2.9 8.3 11.2 6.8 7.1 11.2 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGG19687.1 - 6.5 7.6 9.1 19 6.1 9.1 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF Thiolase_N PF00108.23 EGG19688.1 - 6.1e-85 284.7 0.1 1.2e-84 283.8 0.1 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGG19688.1 - 3.1e-42 143.1 0.6 6.9e-42 142.0 0.6 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGG19688.1 - 7.4e-05 22.4 0.2 0.00058 19.5 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGG19688.1 - 0.12 12.2 0.3 1 9.2 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PseudoU_synth_1 PF01416.20 EGG19689.1 - 2.2e-14 53.8 0.0 4.1e-11 43.3 0.0 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase DUF3669 PF12417.8 EGG19689.1 - 0.38 11.0 2.2 1.6 9.0 0.1 2.7 2 0 0 2 2 2 0 Zinc finger protein Solute_trans_a PF03619.16 EGG19690.1 - 3.1e-66 223.6 27.4 3.7e-34 118.5 11.0 2.2 1 1 1 2 2 2 2 Organic solute transporter Ostalpha Rho_N PF07498.12 EGG19692.1 - 0.0017 18.2 0.6 0.0033 17.3 0.6 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain UvrB PF12344.8 EGG19692.1 - 0.22 11.4 4.2 6.6 6.7 0.4 3.0 2 0 0 2 2 2 0 Ultra-violet resistance protein B N1221 PF07923.13 EGG19694.1 - 0.013 14.7 2.6 0.025 13.8 2.6 1.4 1 0 0 1 1 1 0 N1221-like protein GTP_EFTU PF00009.27 EGG19695.1 - 9.7e-61 204.7 0.0 1.5e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGG19695.1 - 9.9e-36 122.2 0.0 2.5e-35 120.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EGG19695.1 - 2.4e-32 110.9 0.0 6.8e-32 109.4 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EGG19695.1 - 2.2e-25 88.5 0.0 4.6e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGG19695.1 - 5e-10 39.6 0.0 1.5e-09 38.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGG19695.1 - 6.4e-07 29.3 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EGG19695.1 - 0.001 19.1 0.1 0.0023 18.0 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.5 EGG19695.1 - 0.0046 17.4 0.1 0.39 11.2 0.0 3.2 3 0 0 3 3 3 1 Avirulence AvrPtoB, BAK1-binding domain AIG1 PF04548.16 EGG19695.1 - 0.0069 15.7 0.0 0.069 12.5 0.0 2.1 2 0 0 2 2 2 1 AIG1 family DUF442 PF04273.13 EGG19695.1 - 0.039 14.0 0.0 17 5.5 0.0 3.1 3 0 0 3 3 3 0 Putative phosphatase (DUF442) AglB_L1 PF18079.1 EGG19695.1 - 0.04 14.2 0.9 2.2 8.7 0.0 2.6 2 0 0 2 2 2 0 Archaeal glycosylation protein B long peripheral domain PPP4R2 PF09184.11 EGG19696.1 - 0.032 13.8 0.1 0.076 12.6 0.0 1.6 2 0 0 2 2 2 0 PPP4R2 Chordopox_L2 PF05803.12 EGG19696.1 - 0.16 11.8 3.1 0.19 11.6 0.2 2.6 2 0 0 2 2 2 0 Chordopoxvirus L2 protein Glyco_hydro_7 PF00840.20 EGG19697.1 - 1.4e-200 666.6 8.4 1.6e-200 666.4 8.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Gly-zipper_YMGG PF13441.6 EGG19698.1 - 0.00015 21.5 4.6 0.0072 16.0 1.4 2.6 3 0 0 3 3 3 2 YMGG-like Gly-zipper Tim17 PF02466.19 EGG19698.1 - 0.00035 20.9 0.9 0.00072 19.9 0.8 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.6 EGG19698.1 - 2.6 8.1 14.7 1.2 9.2 7.3 2.4 2 0 0 2 2 2 0 Glycine zipper Chromo PF00385.24 EGG19699.1 - 3.9e-16 58.7 3.3 1.7e-15 56.6 3.3 2.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CDC27 PF09507.10 EGG19699.1 - 0.00071 19.1 53.3 0.00071 19.1 53.3 4.2 1 1 2 3 3 3 1 DNA polymerase subunit Cdc27 Rft-1 PF04506.13 EGG19700.1 - 3.3e-100 336.2 28.6 4.4e-100 335.9 28.6 1.1 1 0 0 1 1 1 1 Rft protein SHS2_Rpb7-N PF03876.17 EGG19700.1 - 2.8e-13 50.0 0.0 6.2e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EGG19700.1 - 3.1e-11 43.5 0.0 7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain TMEM223 PF14640.6 EGG19700.1 - 0.013 15.7 0.1 0.06 13.5 0.1 2.2 1 0 0 1 1 1 0 Transmembrane protein 223 RNA_pol_Rbc25 PF08292.12 EGG19700.1 - 0.022 15.0 0.1 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 WSC PF01822.19 EGG19701.1 - 5.7e-20 71.3 25.9 9.9e-17 60.9 10.1 4.4 4 0 0 4 4 4 2 WSC domain CAP PF00188.26 EGG19701.1 - 8e-16 59.0 0.1 8e-16 59.0 0.1 3.5 3 0 0 3 3 3 1 Cysteine-rich secretory protein family Ion_trans PF00520.31 EGG19701.1 - 6.9e-07 28.7 16.6 2.8e-05 23.5 14.9 2.6 2 0 0 2 2 2 2 Ion transport protein MarC PF01914.17 EGG19701.1 - 0.1 12.0 1.9 0.18 11.2 1.9 1.3 1 0 0 1 1 1 0 MarC family integral membrane protein zf-C2HC5 PF06221.13 EGG19704.1 - 0.14 12.2 2.7 0.54 10.3 2.7 2.1 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type SOSSC PF15925.5 EGG19704.1 - 0.17 13.2 0.9 0.47 11.8 0.2 2.1 2 0 0 2 2 2 0 SOSS complex subunit C Laminin_EGF PF00053.24 EGG19704.1 - 0.75 10.0 16.4 1.7 8.8 2.5 2.7 2 1 0 2 2 2 0 Laminin EGF domain PBP3 PF18056.1 EGG19707.1 - 0.071 13.2 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 Penicillin Binding Protein 3 Domain Arm PF00514.23 EGG19708.1 - 0.00023 21.1 0.1 0.00051 20.0 0.1 1.6 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat TRP PF06011.12 EGG19708.1 - 0.0041 15.9 5.6 0.0084 14.9 5.6 1.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel HMA PF00403.26 EGG19708.1 - 0.099 13.1 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Heavy-metal-associated domain BUD22 PF09073.10 EGG19708.1 - 0.19 11.0 9.4 0.36 10.1 9.4 1.4 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 EGG19708.1 - 3.7 6.8 14.8 6.1 6.1 14.8 1.3 1 0 0 1 1 1 0 NOA36 protein PsiF_repeat PF07769.14 EGG19709.1 - 0.14 12.0 1.2 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 psiF repeat Pkinase PF00069.25 EGG19711.1 - 5.9e-71 238.9 0.0 1.6e-70 237.5 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19711.1 - 1e-48 165.9 0.0 2.3e-48 164.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Cornichon PF03311.14 EGG19711.1 - 3.6e-34 117.7 18.5 6.2e-34 116.9 18.5 1.4 1 0 0 1 1 1 1 Cornichon protein PBD PF00786.28 EGG19711.1 - 7.3e-16 58.3 0.7 4.1e-15 55.9 0.7 2.4 1 0 0 1 1 1 1 P21-Rho-binding domain Haspin_kinase PF12330.8 EGG19711.1 - 0.0011 17.9 0.3 0.0011 17.9 0.3 2.7 2 1 0 2 2 2 1 Haspin like kinase domain Ank_2 PF12796.7 EGG19712.1 - 7.1e-47 157.9 41.0 1.7e-09 38.1 0.4 7.4 2 2 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19712.1 - 1.3e-30 105.3 16.4 2.2e-06 28.1 0.0 10.1 5 3 6 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19712.1 - 2.5e-25 88.2 14.4 0.0024 18.2 0.0 12.5 4 2 10 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19712.1 - 1.1e-18 65.4 12.1 0.95 10.2 0.0 13.4 14 2 2 16 16 16 5 Ankyrin repeat DUF5049 PF16468.5 EGG19712.1 - 3.2e-09 36.5 12.2 3.1 7.7 0.0 9.1 3 2 6 9 9 9 4 Domain of unknown function (DUF5049) Ank PF00023.30 EGG19712.1 - 8.8e-07 29.1 5.5 12 6.5 0.0 9.1 4 3 4 8 8 8 1 Ankyrin repeat DUF4113 PF13438.6 EGG19712.1 - 0.001 19.1 0.1 9 6.5 0.0 5.3 5 1 2 7 7 7 1 Domain of unknown function (DUF4113) F-box-like PF12937.7 EGG19712.1 - 0.0026 17.6 0.0 0.0069 16.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like FNIP PF05725.12 EGG19712.1 - 0.028 14.6 17.9 0.59 10.3 0.1 6.2 6 2 0 6 6 6 0 FNIP Repeat SR-25 PF10500.9 EGG19712.1 - 1.6 8.3 6.8 2.6 7.6 6.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3818 PF12825.7 EGG19714.1 - 7.6e-18 64.6 1.4 7.6e-18 64.6 1.4 3.9 2 1 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EGG19714.1 - 1.1 9.2 5.3 1.4 8.9 0.5 3.0 1 1 1 2 2 2 0 PX-associated DUF3439 PF11921.8 EGG19714.1 - 7.1 6.6 17.8 5.3 7.0 1.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Sec1 PF00995.23 EGG19715.1 - 1.8e-118 397.3 11.5 2e-118 397.1 11.5 1.0 1 0 0 1 1 1 1 Sec1 family HTH_Tnp_Tc5 PF03221.16 EGG19716.1 - 1.3e-12 47.5 0.2 2.8e-12 46.5 0.2 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.6 EGG19716.1 - 0.024 14.7 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Mif2_N PF15624.6 EGG19716.1 - 0.029 15.1 0.8 0.029 15.1 0.8 2.5 1 1 1 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal SMC_N PF02463.19 EGG19718.1 - 0.029 13.8 1.5 1.3 8.4 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Phage_CI_C PF16452.5 EGG19718.1 - 0.081 13.2 0.1 0.31 11.4 0.1 2.0 1 1 1 2 2 2 0 Bacteriophage CI repressor C-terminal domain Malt_amylase_C PF16657.5 EGG19719.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.6 1 1 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Pox_D5 PF03288.16 EGG19720.1 - 0.00024 21.5 1.6 0.00082 19.8 0.3 2.6 2 0 0 2 2 2 1 Poxvirus D5 protein-like VirE PF05272.11 EGG19720.1 - 0.0051 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Virulence-associated protein E AAA_16 PF13191.6 EGG19720.1 - 0.026 14.9 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 EGG19720.1 - 0.038 13.3 0.1 0.081 12.2 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 EGG19720.1 - 0.066 12.4 0.1 0.15 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 EGG19720.1 - 0.067 13.7 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 EGG19720.1 - 0.071 13.1 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGG19720.1 - 0.088 13.2 0.6 0.79 10.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase rve PF00665.26 EGG19721.1 - 3.9e-11 43.2 0.0 7.7e-11 42.2 0.0 1.5 1 1 1 2 2 2 1 Integrase core domain Chromo PF00385.24 EGG19721.1 - 0.00016 21.5 3.3 0.0004 20.2 3.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CoaE PF01121.20 EGG19721.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase DUF5442 PF17514.2 EGG19721.1 - 0.13 12.5 1.1 2.8 8.2 0.1 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5442) DUF2098 PF09871.9 EGG19721.1 - 0.38 11.1 1.9 2.6 8.5 0.7 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) PUA_2 PF14306.6 EGG19723.1 - 0.038 13.7 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 PUA-like domain AlgF PF11182.8 EGG19723.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF ParB PF08775.10 EGG19723.1 - 0.12 12.8 1.0 0.26 11.8 1.0 1.5 1 0 0 1 1 1 0 ParB family RTX_C PF08339.10 EGG19724.1 - 0.0047 17.0 0.7 0.0096 16.0 0.0 1.8 1 1 1 2 2 2 1 RTX C-terminal domain Ndr PF03096.14 EGG19724.1 - 0.046 12.4 0.3 0.07 11.8 0.3 1.2 1 0 0 1 1 1 0 Ndr family Phasin PF05597.11 EGG19724.1 - 0.059 13.4 6.6 0.6 10.1 2.6 2.2 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Peptidase_C5 PF00770.18 EGG19725.1 - 0.0093 15.6 0.0 0.026 14.2 0.0 1.8 1 0 0 1 1 1 1 Adenovirus endoprotease ELMO_CED12 PF04727.13 EGG19727.1 - 6e-40 137.2 0.1 1.3e-39 136.2 0.1 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family BppL_N PF18338.1 EGG19727.1 - 0.004 16.9 0.1 0.019 14.7 0.1 2.2 1 0 0 1 1 1 1 Lower baseplate protein N-terminal domain ATPase_2 PF01637.18 EGG19727.1 - 0.022 14.6 0.7 0.052 13.5 0.7 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGG19727.1 - 0.054 13.8 0.1 0.23 11.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain NST1 PF13945.6 EGG19727.1 - 0.11 12.6 1.2 0.23 11.5 1.2 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Ank_2 PF12796.7 EGG19728.1 - 1.8e-32 111.7 16.9 6.6e-08 33.0 0.0 7.9 2 1 7 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19728.1 - 2e-32 111.2 15.9 2e-05 25.0 0.2 11.0 8 3 2 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19728.1 - 3.1e-31 107.0 16.6 0.001 19.3 0.0 13.1 4 4 9 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19728.1 - 2.6e-18 64.2 15.6 3 8.7 0.0 14.3 14 1 1 15 15 15 4 Ankyrin repeat Ank PF00023.30 EGG19728.1 - 3.3e-07 30.4 6.2 20 5.8 0.0 9.4 8 3 0 8 8 8 1 Ankyrin repeat DUF5049 PF16468.5 EGG19728.1 - 2e-05 24.4 0.0 4.5 7.2 0.0 6.9 7 2 2 9 9 9 1 Domain of unknown function (DUF5049) DUF2462 PF09495.10 EGG19728.1 - 0.052 14.3 1.2 0.13 13.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) SUIM_assoc PF16619.5 EGG19728.1 - 2.8 8.1 8.2 7.3 6.7 8.2 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Amastin PF07344.11 EGG19729.1 - 0.0039 17.1 1.8 0.0058 16.5 1.8 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 EGG19731.1 - 0.032 14.1 2.4 0.05 13.5 2.2 1.5 1 1 0 1 1 1 0 Amastin surface glycoprotein Pex24p PF06398.11 EGG19731.1 - 3.9 6.4 6.1 5.3 5.9 5.5 1.5 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF4231 PF14015.6 EGG19731.1 - 5.1 7.6 5.3 8.2 7.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF3360 PF11840.8 EGG19732.1 - 0.00054 18.8 0.3 0.00076 18.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3360) Amastin PF07344.11 EGG19732.1 - 0.0017 18.2 3.3 0.0024 17.7 2.9 1.6 1 1 0 1 1 1 1 Amastin surface glycoprotein DUF1624 PF07786.12 EGG19732.1 - 0.4 10.2 10.2 0.034 13.7 5.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1624) DUF2070 PF09843.9 EGG19732.1 - 0.6 8.3 6.3 0.69 8.1 6.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Tmemb_cc2 PF10267.9 EGG19732.1 - 0.96 8.5 1.7 1.2 8.2 1.7 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Ank_4 PF13637.6 EGG19733.1 - 2.7e-32 110.7 15.9 4.8e-05 23.8 0.0 10.2 7 3 4 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19733.1 - 7.6e-28 96.2 15.0 0.0003 21.0 0.1 11.9 4 2 10 14 14 14 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG19733.1 - 5.3e-26 91.0 17.4 8.6e-06 26.3 0.5 7.7 1 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG19733.1 - 4.6e-10 38.8 13.9 12 6.9 0.0 13.4 14 2 2 16 16 16 1 Ankyrin repeat DUF5049 PF16468.5 EGG19733.1 - 6.5e-08 32.3 0.1 5.5 7.0 0.0 7.3 6 1 1 7 7 7 2 Domain of unknown function (DUF5049) Tetraspanin PF00335.20 EGG19733.1 - 0.96 9.1 3.7 2.9 7.5 3.7 1.8 1 0 0 1 1 1 0 Tetraspanin family S_4TM PF18159.1 EGG19734.1 - 0.14 11.4 0.2 0.24 10.7 0.1 1.5 1 1 0 1 1 1 0 SMODS-associating 4TM effector domain DUF3392 PF11872.8 EGG19734.1 - 0.31 11.3 3.6 0.39 11.0 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) Amastin PF07344.11 EGG19734.1 - 0.46 10.3 11.1 2 8.2 10.0 2.4 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF2721 PF11026.8 EGG19734.1 - 0.49 10.3 5.2 0.68 9.8 1.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) zf-C3Hc3H PF13891.6 EGG19736.1 - 3.6e-08 33.6 5.8 7.2e-08 32.7 5.8 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain zf-primase PF09329.11 EGG19736.1 - 0.00074 19.3 0.8 0.00074 19.3 0.8 1.9 2 0 0 2 2 2 1 Primase zinc finger zf-TRM13_CCCH PF11722.8 EGG19736.1 - 0.54 10.1 7.0 5.6 6.8 2.3 2.6 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein EMC3_TMCO1 PF01956.16 EGG19737.1 - 1.2e-48 165.1 3.1 1.2e-48 165.1 3.1 1.7 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like FtsH_ext PF06480.15 EGG19737.1 - 0.093 13.1 1.2 2.4 8.5 0.1 2.5 2 1 0 2 2 2 0 FtsH Extracellular CENP-B_dimeris PF09026.10 EGG19738.1 - 0.14 12.6 7.7 0.061 13.7 5.2 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EGG19738.1 - 0.62 9.3 6.9 0.87 8.8 6.9 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 EGG19738.1 - 2.6 7.8 10.2 6.3 6.5 10.2 1.6 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Ank_5 PF13857.6 EGG19739.1 - 2.2e-30 104.3 2.9 0.0014 18.9 0.0 11.4 2 1 10 12 12 12 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG19739.1 - 5.2e-29 100.7 1.4 1.6e-08 35.0 0.0 7.0 2 1 7 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19739.1 - 1.5e-28 98.8 7.9 0.00034 21.1 0.0 9.9 7 4 4 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19739.1 - 3.9e-16 57.5 0.1 9.1 7.2 0.0 12.1 12 1 1 13 13 13 2 Ankyrin repeat DUF5049 PF16468.5 EGG19739.1 - 2e-07 30.8 1.7 0.78 9.7 0.1 7.8 7 3 4 11 11 11 2 Domain of unknown function (DUF5049) rve_3 PF13683.6 EGG19739.1 - 0.0014 18.4 0.7 0.0033 17.2 0.7 1.6 1 0 0 1 1 1 1 Integrase core domain Ank PF00023.30 EGG19739.1 - 0.0098 16.3 0.1 2.7e+02 2.3 0.0 6.6 6 3 0 6 6 6 0 Ankyrin repeat Ndc80_HEC PF03801.13 EGG19739.1 - 0.013 15.2 0.0 9.7 5.8 0.0 4.2 3 1 0 3 3 3 0 HEC/Ndc80p family Ank_2 PF12796.7 EGG19740.1 - 6.6e-15 55.5 7.0 0.0001 22.8 0.8 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19740.1 - 1.2e-12 48.0 6.1 0.0023 18.5 0.1 6.5 2 2 5 8 8 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19740.1 - 1.9e-12 47.1 4.0 0.35 11.2 0.0 7.3 3 1 4 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19740.1 - 1.6e-07 31.0 6.5 5 8.0 0.0 8.6 10 1 1 11 11 11 1 Ankyrin repeat DUF5049 PF16468.5 EGG19740.1 - 0.0013 18.6 0.1 3.3 7.7 0.0 4.9 6 0 0 6 6 6 1 Domain of unknown function (DUF5049) Tom37 PF10568.9 EGG19740.1 - 0.0059 16.9 0.7 0.18 12.1 0.0 3.2 3 1 0 4 4 4 1 Outer mitochondrial membrane transport complex protein WW_1 PF18507.1 EGG19740.1 - 0.072 12.8 0.3 0.19 11.4 0.3 1.7 1 0 0 1 1 1 0 WW domain Ank_4 PF13637.6 EGG19741.1 - 6.8e-11 42.5 1.5 7.2e-07 29.6 0.0 3.2 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19741.1 - 3.6e-10 39.9 1.6 0.00056 20.2 0.1 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG19741.1 - 2.8e-08 34.2 2.7 5.7e-05 23.6 0.4 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG19741.1 - 3.3e-07 30.1 0.4 3.4 8.5 0.0 5.1 5 1 1 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 EGG19742.1 - 1e-34 118.9 12.4 4.5e-09 36.8 0.3 5.7 2 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG19742.1 - 2.8e-30 104.0 8.8 0.00023 21.4 0.0 11.5 3 3 9 12 12 12 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG19742.1 - 5.6e-30 103.3 14.9 0.00014 22.4 0.0 9.1 4 2 6 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19742.1 - 6.3e-18 63.0 8.6 3.3 8.6 0.0 13.5 12 2 2 14 14 14 3 Ankyrin repeat Ank PF00023.30 EGG19742.1 - 5.3e-07 29.8 5.4 33 5.1 0.0 9.8 2 2 7 9 9 9 0 Ankyrin repeat DUF5049 PF16468.5 EGG19742.1 - 5.5e-05 23.0 1.0 42 4.1 0.0 7.4 4 3 4 8 8 8 0 Domain of unknown function (DUF5049) Lipoprotein_Ltp PF07553.11 EGG19742.1 - 0.054 13.7 0.0 0.51 10.6 0.0 2.7 2 1 1 3 3 3 0 Host cell surface-exposed lipoprotein HEAT_2 PF13646.6 EGG19743.1 - 0.00011 22.5 0.0 0.01 16.2 0.0 3.6 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 EGG19743.1 - 0.00046 20.2 2.5 0.84 10.1 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat IBN_N PF03810.19 EGG19743.1 - 0.0057 16.5 0.4 0.017 15.0 0.4 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Orf78 PF06024.12 EGG19745.1 - 4.1 7.7 7.3 14 6.1 0.3 3.4 3 0 0 3 3 3 0 Orf78 (ac78) DUF2090 PF09863.9 EGG19746.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) DUF5582 PF17819.1 EGG19746.1 - 0.12 12.8 1.9 17 5.8 0.0 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5582) Ank_5 PF13857.6 EGG19747.1 - 1.6e-25 88.8 18.9 0.00042 20.6 0.3 10.7 4 3 7 11 11 11 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG19747.1 - 2.8e-24 85.1 14.4 0.0004 20.9 0.2 8.8 6 3 4 10 10 10 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG19747.1 - 5.2e-24 84.6 20.1 3e-08 34.1 0.3 7.2 1 1 7 8 8 8 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG19747.1 - 9.9e-11 40.9 13.6 33 5.5 0.0 13.1 13 2 2 15 15 15 0 Ankyrin repeat DUF5049 PF16468.5 EGG19747.1 - 0.0004 20.2 2.8 39 4.3 0.0 6.6 5 2 4 9 9 9 0 Domain of unknown function (DUF5049) Ndc80_HEC PF03801.13 EGG19747.1 - 0.007 16.0 0.6 0.22 11.2 0.1 3.2 2 2 0 2 2 2 1 HEC/Ndc80p family Ank PF00023.30 EGG19747.1 - 0.0082 16.6 6.0 58 4.4 0.1 7.5 5 2 1 6 6 6 0 Ankyrin repeat Bin3 PF06859.12 EGG19747.1 - 0.054 14.1 0.2 1.4 9.6 0.1 3.4 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) APP_Cu_bd PF12924.7 EGG19747.1 - 2.9 8.7 8.0 37 5.2 0.2 5.4 6 0 0 6 6 6 0 Copper-binding of amyloid precursor, CuBD DUF3446 PF11928.8 EGG19748.1 - 0.035 14.4 18.2 0.047 14.0 6.9 3.7 3 0 0 3 3 3 0 Early growth response N-terminal domain DUF2681 PF10883.8 EGG19748.1 - 0.089 13.2 13.8 0.29 11.6 13.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Sec62 PF03839.16 EGG19748.1 - 0.46 10.0 5.2 1 8.8 5.2 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 CobT PF06213.12 EGG19748.1 - 1.1 8.7 10.7 1.8 7.9 10.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.6 EGG19748.1 - 1.6 8.4 5.0 4.5 6.9 5.0 1.7 1 0 0 1 1 1 0 FAM176 family Pet20 PF08692.10 EGG19748.1 - 2.2 9.0 15.6 0.11 13.2 6.4 2.7 2 1 0 2 2 2 0 Mitochondrial protein Pet20 SR-25 PF10500.9 EGG19748.1 - 3 7.4 24.1 0.048 13.3 16.6 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DivIC PF04977.15 EGG19748.1 - 5.6 6.8 14.6 3.4 7.5 12.1 1.9 2 0 0 2 2 2 0 Septum formation initiator Androgen_recep PF02166.16 EGG19748.1 - 5.7 5.7 21.5 0.16 10.8 15.2 1.7 2 0 0 2 2 2 0 Androgen receptor DUF4175 PF13779.6 EGG19748.1 - 6.3 4.6 15.5 9.2 4.0 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) NEMP PF10225.9 EGG19748.1 - 6.8 6.3 7.6 9.4 5.8 7.6 1.2 1 0 0 1 1 1 0 NEMP family TERB2 PF15101.6 EGG19748.1 - 8 6.4 19.0 0.45 10.5 12.9 1.9 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DDE_Tnp_4 PF13359.6 EGG19749.1 - 2.6e-24 85.7 0.0 4.7e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 EGG19749.1 - 1.7e-09 37.3 0.2 3e-09 36.5 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGG19749.1 - 0.0009 18.9 0.0 0.0009 18.9 0.0 2.2 2 2 0 2 2 2 1 Transposase DDE domain Presenilin PF01080.17 EGG19749.1 - 0.093 11.5 4.2 0.13 11.0 4.2 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 EGG19749.1 - 0.095 12.5 8.4 0.15 11.9 8.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 EGG19749.1 - 0.18 10.7 3.3 0.27 10.2 3.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 EGG19749.1 - 0.46 9.6 1.9 0.6 9.3 1.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 EGG19749.1 - 0.98 7.6 12.1 1.7 6.8 12.1 1.3 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 EGG19749.1 - 1.8 8.7 6.1 3.1 8.0 6.1 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal HEPN_Swt1 PF18731.1 EGG19749.1 - 2 8.8 4.2 20 5.6 0.3 3.0 3 0 0 3 3 3 0 Swt1-like HEPN FNIP PF05725.12 EGG19751.1 - 1.8e-89 293.7 36.2 4.9e-16 58.6 0.2 10.2 6 3 5 12 12 12 11 FNIP Repeat Pkinase PF00069.25 EGG19751.1 - 6.1e-24 84.8 2.8 1.1e-23 83.9 2.8 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19751.1 - 4.3e-09 36.0 0.1 3.8e-08 32.9 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EGG19751.1 - 0.00059 19.5 0.4 0.0013 18.3 0.4 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 EGG19751.1 - 0.031 13.6 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Thx PF17070.5 EGG19751.1 - 0.32 11.1 2.3 0.73 10.0 2.3 1.5 1 0 0 1 1 1 0 30S ribosomal protein Thx NPH3 PF03000.14 EGG19753.1 - 0.0018 18.0 0.7 0.0043 16.7 0.7 1.7 1 0 0 1 1 1 1 NPH3 family GHD PF17834.1 EGG19754.1 - 0.16 12.0 2.0 0.3 11.2 0.5 2.3 1 1 1 2 2 2 0 Beta-sandwich domain in beta galactosidase VPS13 PF16908.5 EGG19755.1 - 8.9e-65 218.8 1.8 8.9e-65 218.8 1.8 3.8 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 EGG19755.1 - 1.1e-46 159.2 29.0 7.6e-28 97.5 0.6 7.4 7 0 0 7 7 7 4 Repeating coiled region of VPS13 Chorein_N PF12624.7 EGG19755.1 - 1.5e-38 131.5 0.5 1.5e-38 131.5 0.5 4.9 5 0 0 5 5 5 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 EGG19755.1 - 3.2e-31 108.5 7.1 3.3e-30 105.2 0.1 3.8 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EGG19755.1 - 1.4e-29 103.4 4.9 1.4e-29 103.4 4.9 4.6 5 0 0 5 5 5 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 EGG19755.1 - 1.5e-09 38.1 0.0 4.2e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Apt1 PF10351.9 EGG19755.1 - 8.5e-05 21.6 0.0 8.5e-05 21.6 0.0 7.8 8 2 0 9 9 9 4 Golgi-body localisation protein domain Tim17 PF02466.19 EGG19756.1 - 6.6e-11 42.6 4.0 1.2e-10 41.7 4.0 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family GST_C_2 PF13410.6 EGG19756.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SKG6 PF08693.10 EGG19758.1 - 0.03 13.7 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1682 PF07946.14 EGG19759.1 - 6.3e-81 272.1 8.0 7.7e-81 271.8 8.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) CDC45 PF02724.14 EGG19759.1 - 0.66 8.2 7.9 25 3.0 0.0 2.0 2 0 0 2 2 2 0 CDC45-like protein CLN3 PF02487.17 EGG19759.1 - 1 8.4 6.4 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 CLN3 protein Presenilin PF01080.17 EGG19759.1 - 5.3 5.7 7.6 80 1.8 7.5 2.1 2 0 0 2 2 2 0 Presenilin DUF3149 PF11346.8 EGG19759.1 - 6.7 6.4 8.1 0.19 11.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) PGM_PMM_I PF02878.16 EGG19760.1 - 1.8e-30 105.4 0.1 1.8e-29 102.2 0.0 2.6 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EGG19760.1 - 4.9e-22 78.5 0.1 1e-21 77.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EGG19760.1 - 9.4e-19 67.7 0.0 2.9e-18 66.1 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EGG19760.1 - 1e-07 32.0 0.0 2.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain CinA_KH PF18146.1 EGG19760.1 - 0.17 12.1 1.0 0.35 11.0 1.0 1.5 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain PhoLip_ATPase_C PF16212.5 EGG19761.1 - 2e-44 152.2 15.6 2e-44 152.2 15.6 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGG19761.1 - 7.1e-17 60.9 9.2 7.1e-17 60.9 9.2 2.8 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGG19761.1 - 2.8e-12 47.4 0.1 0.00098 19.5 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG19761.1 - 4.7e-11 42.6 0.0 3.8e-09 36.5 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGG19761.1 - 2.8e-09 36.7 0.0 8.2e-09 35.2 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGG19761.1 - 0.0014 18.4 0.0 0.0014 18.4 0.0 3.0 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.17 EGG19762.1 - 3e-47 161.1 0.0 4.8e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG19762.1 - 2.2e-45 155.1 0.0 4.2e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 EGG19762.1 - 5.7e-26 90.8 0.0 1.3e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain Ank_2 PF12796.7 EGG19762.1 - 1.4e-16 60.9 0.2 9e-11 42.2 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19762.1 - 6.7e-12 45.7 0.0 6.8e-05 23.3 0.0 3.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG19762.1 - 7.2e-10 38.9 0.0 6.1e-05 23.2 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Haspin_kinase PF12330.8 EGG19762.1 - 6.5e-09 35.2 0.5 1e-07 31.3 0.5 2.4 1 1 0 1 1 1 1 Haspin like kinase domain Ank_3 PF13606.6 EGG19762.1 - 5e-08 32.6 0.0 0.00096 19.4 0.0 4.2 4 0 0 4 4 3 2 Ankyrin repeat Ank PF00023.30 EGG19762.1 - 3.2e-07 30.5 0.0 0.03 14.8 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat SAM_1 PF00536.30 EGG19762.1 - 4.9e-07 30.1 0.5 1.3e-06 28.7 0.5 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGG19762.1 - 3.2e-06 27.2 0.3 8e-06 25.9 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 EGG19762.1 - 0.049 12.4 0.0 0.09 11.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGG19762.1 - 0.19 11.6 0.1 0.39 10.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mob1_phocein PF03637.17 EGG19763.1 - 6.5e-35 120.6 3.0 9.3e-35 120.1 3.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family AAA_35 PF14516.6 EGG19764.1 - 0.00028 19.8 0.0 0.00061 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain phiKZ_IP PF12699.7 EGG19765.1 - 0.044 12.9 0.1 0.084 12.0 0.1 1.4 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Nop14 PF04147.12 EGG19766.1 - 0.043 12.1 16.7 0.043 12.0 16.7 1.0 1 0 0 1 1 1 0 Nop14-like family EIIBC-GUT_N PF03612.14 EGG19766.1 - 0.12 12.1 2.2 0.13 12.0 2.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TRAP_alpha PF03896.16 EGG19766.1 - 0.62 9.2 10.3 0.69 9.1 10.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 EGG19766.1 - 5.4 5.2 14.7 5.7 5.1 14.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DDE_Tnp_1_7 PF13843.6 EGG19767.1 - 1.4e-28 100.2 1.5 2e-28 99.7 0.1 2.0 2 0 0 2 2 2 1 Transposase IS4 AAA_7 PF12775.7 EGG19768.1 - 0.066 12.7 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_35 PF14516.6 EGG19768.1 - 0.094 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ATPase_2 PF01637.18 EGG19768.1 - 0.1 12.5 0.6 0.25 11.2 0.2 1.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea MobB PF03205.14 EGG19768.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_S14 PF00253.21 EGG19769.1 - 2.5e-13 49.6 1.6 4.5e-13 48.7 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ank_5 PF13857.6 EGG19769.1 - 0.059 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Pkinase PF00069.25 EGG19770.1 - 2.1e-69 233.8 0.0 2.8e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19770.1 - 3.6e-27 95.3 0.0 8.3e-27 94.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG19770.1 - 4.2e-06 26.3 0.0 9.6e-06 25.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG19770.1 - 0.0041 16.5 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG19770.1 - 0.0067 16.4 0.0 0.035 14.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGG19770.1 - 0.029 13.9 0.5 0.085 12.4 0.5 1.9 1 1 0 1 1 1 0 Choline/ethanolamine kinase Menin PF05053.13 EGG19770.1 - 0.22 9.8 6.5 0.4 9.0 6.5 1.4 1 0 0 1 1 1 0 Menin Tmemb_185A PF10269.9 EGG19771.1 - 8.1e-54 182.9 23.1 1.4e-53 182.2 23.1 1.4 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DnaJ PF00226.31 EGG19771.1 - 4.5e-26 90.8 2.0 6.8e-26 90.2 2.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1980 PF09323.10 EGG19771.1 - 7.4 6.4 11.4 1.9 8.4 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PA14 PF07691.12 EGG19772.1 - 1.7e-06 27.9 0.0 3.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGG19772.1 - 2.1e-05 24.3 18.6 3.1e-05 23.8 3.9 16.0 15 1 0 15 15 15 8 Dictyostelium (slime mold) repeat FNIP PF05725.12 EGG19773.1 - 5.1e-187 605.9 39.2 1.1e-16 60.7 0.1 14.7 7 2 5 16 16 16 16 FNIP Repeat Pkinase PF00069.25 EGG19773.1 - 1.5e-22 80.2 0.4 3.9e-22 78.9 0.4 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19773.1 - 3.3e-06 26.6 0.0 0.001 18.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Filament PF00038.21 EGG19774.1 - 0.0034 17.0 55.6 0.0034 17.0 55.6 12.6 2 2 9 11 11 11 6 Intermediate filament protein DUF3450 PF11932.8 EGG19774.1 - 0.0046 16.3 7.3 0.0046 16.3 7.3 20.7 1 1 22 24 24 24 3 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 EGG19774.1 - 0.0073 16.1 2.6 0.0073 16.1 2.6 20.5 2 2 15 20 20 20 4 Phage minor structural protein GP20 Pkinase PF00069.25 EGG19775.1 - 6.2e-68 229.0 0.0 7.4e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19775.1 - 9.6e-32 110.3 0.0 1.6e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG19775.1 - 0.01 14.8 0.0 0.02 13.9 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EGG19775.1 - 0.021 14.2 0.1 0.1 12.0 0.1 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGG19775.1 - 0.21 10.9 0.1 1.8 7.8 0.0 2.3 1 1 1 2 2 2 0 Kinase-like FNIP PF05725.12 EGG19776.1 - 1.4e-66 220.4 9.6 3e-16 59.3 0.0 6.1 6 0 0 6 6 6 5 FNIP Repeat DUF1496 PF07383.12 EGG19776.1 - 0.032 13.8 0.1 0.072 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1496) Phage_min_tail PF05939.13 EGG19776.1 - 0.036 14.4 0.1 40 4.6 0.1 4.6 4 2 2 6 6 6 0 Phage minor tail protein FNIP PF05725.12 EGG19777.1 - 4.2e-13 49.2 1.2 0.0012 19.0 0.1 3.5 3 0 0 3 3 3 3 FNIP Repeat Methyltransf_23 PF13489.6 EGG19778.1 - 2.4e-15 56.8 0.0 3.9e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG19778.1 - 5e-15 56.1 0.3 1.1e-13 51.7 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG19778.1 - 5.6e-12 46.2 0.1 1.1e-11 45.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG19778.1 - 5.9e-10 39.1 0.0 9.3e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG19778.1 - 1.2e-09 38.7 0.1 2.1e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG19778.1 - 0.00015 21.4 0.0 0.0003 20.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 EGG19778.1 - 0.00027 20.5 0.0 0.95 8.9 0.0 2.5 2 1 0 3 3 3 2 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 EGG19778.1 - 0.00078 18.9 0.0 0.0037 16.7 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 EGG19778.1 - 0.0012 18.2 0.0 0.0025 17.2 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 EGG19778.1 - 0.0017 17.9 0.0 0.0033 17.0 0.0 1.5 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TPMT PF05724.11 EGG19778.1 - 0.0056 16.4 0.1 0.012 15.3 0.1 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NNMT_PNMT_TEMT PF01234.17 EGG19778.1 - 0.006 15.8 0.6 0.49 9.5 0.0 2.1 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family DUF3419 PF11899.8 EGG19778.1 - 0.0066 15.7 0.4 0.027 13.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.6 EGG19778.1 - 0.0069 17.4 0.0 0.017 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGG19778.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase zf-HIT PF04438.16 EGG19780.1 - 3.4e-05 23.6 6.6 7.5e-05 22.5 6.6 1.5 1 0 0 1 1 1 1 HIT zinc finger Ank_3 PF13606.6 EGG19780.1 - 0.068 13.8 0.2 4e+02 2.2 0.0 5.3 5 0 0 5 5 5 0 Ankyrin repeat zf-MYND PF01753.18 EGG19780.1 - 3.3 7.9 7.4 6.8 6.9 7.4 1.5 1 0 0 1 1 1 0 MYND finger DUF2704 PF10866.8 EGG19781.1 - 1.4 8.7 8.2 0.2 11.5 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2704) DUF1388 PF07142.12 EGG19782.1 - 0.045 13.7 5.8 0.12 12.4 2.3 2.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) Cyclin_N PF00134.23 EGG19783.1 - 1e-05 25.3 1.5 1.3e-05 25.0 0.2 2.0 2 1 0 2 2 2 1 Cyclin, N-terminal domain CobT_C PF11775.8 EGG19783.1 - 0.0095 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT VWA domain Cyclin PF08613.11 EGG19783.1 - 0.023 15.1 0.1 0.023 15.1 0.1 2.2 3 1 0 3 3 3 0 Cyclin DUF368 PF04018.13 EGG19783.1 - 0.17 11.4 2.1 7.5 6.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF368) Response_reg PF00072.24 EGG19784.1 - 1.4e-22 79.9 0.0 2.3e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Cwf_Cwc_15 PF04889.12 EGG19784.1 - 0.00088 19.1 7.2 0.00088 19.1 7.2 1.9 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Aldo_ket_red PF00248.21 EGG19785.1 - 1.4e-52 178.8 0.0 1.5e-50 172.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sec3_C PF09763.9 EGG19786.1 - 2.3e-135 452.7 26.2 2.3e-135 452.7 26.2 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec3 CCDC-167 PF15188.6 EGG19786.1 - 0.036 14.4 0.1 0.12 12.8 0.1 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 HBM PF16591.5 EGG19786.1 - 0.045 13.2 0.4 0.16 11.3 0.2 2.0 1 1 1 2 2 2 0 Helical bimodular sensor domain DUF4276 PF14103.6 EGG19786.1 - 0.23 11.7 1.9 1.3 9.2 0.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4276) Peptidase_U49 PF10463.9 EGG19786.1 - 0.24 11.1 4.7 0.16 11.7 0.1 2.7 3 0 0 3 3 3 0 Peptidase U49 Hist_deacetyl PF00850.19 EGG19787.1 - 1.4e-65 221.8 0.5 2e-65 221.3 0.5 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MORN PF02493.20 EGG19788.1 - 8.5e-24 82.0 68.8 4.3e-07 29.5 0.2 12.2 13 1 0 13 13 13 7 MORN repeat KASH_CCD PF14662.6 EGG19788.1 - 0.14 12.0 4.4 0.22 11.3 4.4 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH SM-ATX PF14438.6 EGG19788.1 - 0.67 10.1 4.2 9.3 6.5 0.3 3.3 3 1 0 3 3 3 0 Ataxin 2 SM domain Nup35_RRM PF05172.13 EGG19789.1 - 6.5e-09 35.7 0.0 2.3e-08 33.9 0.0 2.0 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif EII-GUT PF03608.13 EGG19789.1 - 0.095 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor DUF3666 PF12408.8 EGG19791.1 - 0.01 15.0 0.0 0.031 13.5 0.0 1.8 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase OxoGdeHyase_C PF16870.5 EGG19791.1 - 0.031 14.0 0.5 0.031 14.0 0.5 2.2 3 0 0 3 3 3 0 2-oxoglutarate dehydrogenase C-terminal fn3 PF00041.21 EGG19793.1 - 2e-11 44.1 5.7 0.00065 20.0 0.4 3.8 4 0 0 4 4 4 3 Fibronectin type III domain EGF_2 PF07974.13 EGG19793.1 - 0.0068 16.8 12.4 0.0068 16.8 12.4 3.3 5 0 0 5 5 5 1 EGF-like domain I-EGF_1 PF18372.1 EGG19793.1 - 0.067 13.3 7.4 0.19 11.8 7.4 1.8 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Pur_ac_phosph_N PF16656.5 EGG19793.1 - 1.7 9.3 8.0 1.9 9.1 0.8 3.9 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Glycophorin_A PF01102.18 EGG19794.1 - 0.2 11.9 1.9 0.24 11.7 0.8 1.6 1 1 0 1 1 1 0 Glycophorin A DUF3302 PF11742.8 EGG19794.1 - 0.38 10.9 6.3 0.6 10.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) DUF2417 PF10329.9 EGG19794.1 - 1.4 8.3 11.6 0.5 9.8 8.2 2.0 1 1 2 3 3 3 0 Region of unknown function (DUF2417) EMP70 PF02990.16 EGG19796.1 - 7.2e-201 668.4 8.1 1.1e-200 667.8 8.1 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 DUF1480 PF07351.13 EGG19796.1 - 0.17 12.2 0.2 21 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1480) AIG1 PF04548.16 EGG19797.1 - 4.2e-10 39.3 0.1 5.7e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EGG19797.1 - 8.8e-09 35.5 0.2 6.1e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGG19797.1 - 2.7e-06 27.5 0.0 4.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EGG19797.1 - 8.5e-05 22.0 0.0 0.00017 21.0 0.0 1.6 1 1 0 1 1 1 1 Septin G-alpha PF00503.20 EGG19797.1 - 0.00044 19.5 1.2 0.057 12.6 0.7 2.8 1 1 2 3 3 3 1 G-protein alpha subunit AAA_29 PF13555.6 EGG19797.1 - 0.00051 19.7 0.0 0.0027 17.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EGG19797.1 - 0.00097 19.7 0.0 0.01 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGG19797.1 - 0.001 19.6 0.0 0.0017 18.9 0.0 1.6 1 1 0 1 1 1 1 ABC transporter ATP_bind_1 PF03029.17 EGG19797.1 - 0.0032 17.3 0.3 0.24 11.1 0.0 2.7 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EGG19797.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 EGG19797.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 EGG19797.1 - 0.014 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 EGG19797.1 - 0.017 14.5 0.1 0.044 13.1 0.1 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 EGG19797.1 - 0.047 13.8 0.2 0.33 11.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain SopA PF13981.6 EGG19797.1 - 0.053 13.9 0.1 0.13 12.7 0.1 1.6 1 1 0 1 1 1 0 SopA-like central domain AAA_15 PF13175.6 EGG19797.1 - 0.071 12.8 0.3 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 EGG19797.1 - 0.074 13.3 0.0 0.24 11.6 0.0 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EGG19797.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.5 2 0 0 2 2 1 0 AAA domain Guanylate_kin PF00625.21 EGG19797.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase AAA_21 PF13304.6 EGG19797.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGG19797.1 - 0.12 12.7 0.0 0.31 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGG19797.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Dzip-like_N PF13815.6 EGG19798.1 - 0.18 11.8 0.3 0.18 11.8 0.3 2.1 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal FNIP PF05725.12 EGG19799.1 - 2.9e-138 449.8 19.9 1.2e-16 60.6 0.2 11.3 10 1 1 11 11 11 11 FNIP Repeat Pkinase PF00069.25 EGG19799.1 - 2.5e-20 73.0 1.6 7.1e-20 71.5 1.6 1.7 1 1 0 1 1 1 1 Protein kinase domain Phage_min_tail PF05939.13 EGG19799.1 - 6.4e-09 36.2 1.4 21 5.5 0.0 9.1 3 2 5 9 9 9 2 Phage minor tail protein Pkinase_Tyr PF07714.17 EGG19799.1 - 8.3e-06 25.3 0.0 0.0024 17.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Amidase02_C PF12123.8 EGG19800.1 - 0.045 13.4 0.9 0.077 12.7 0.1 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DNA_pol3_finger PF17657.1 EGG19801.1 - 0.0065 15.8 0.3 0.011 15.1 0.3 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain DUF2798 PF11391.8 EGG19801.1 - 0.14 12.2 0.2 0.36 10.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) Cadherin_C PF01049.17 EGG19801.1 - 0.19 12.0 0.6 0.4 11.0 0.6 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic region YjbE PF11106.8 EGG19801.1 - 7.9 6.8 11.7 14 6.0 11.7 1.4 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Glutaredoxin PF00462.24 EGG19802.1 - 0.001 19.3 0.0 0.002 18.3 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin DLH PF01738.18 EGG19803.1 - 1.4e-36 126.1 0.0 1.8e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EGG19803.1 - 1.4e-06 28.3 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EGG19803.1 - 0.0022 17.7 0.1 0.005 16.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 EGG19803.1 - 0.0054 16.7 0.1 0.015 15.2 0.1 1.6 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase PF07224.11 EGG19803.1 - 0.027 13.5 0.0 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase Peptidase_S9 PF00326.21 EGG19803.1 - 0.036 13.5 1.9 0.046 13.2 0.2 2.0 2 1 1 3 3 3 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGG19803.1 - 0.039 13.2 0.2 1.7 7.8 0.0 2.3 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DUF2048 PF09752.9 EGG19803.1 - 0.13 11.3 0.3 6.1 5.8 0.0 2.1 1 1 1 2 2 2 0 Abhydrolase domain containing 18 RNB PF00773.19 EGG19804.1 - 1.1e-58 199.2 0.6 2.1e-57 194.9 0.6 2.6 1 1 0 1 1 1 1 RNB domain Peptidase_S49_N PF08496.10 EGG19804.1 - 2.4 8.2 5.2 0.43 10.6 0.9 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Porph_ging PF09697.10 EGG19804.1 - 9.2 6.9 5.9 13 6.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (Porph_ging) Ank_2 PF12796.7 EGG19805.1 - 3.8e-27 94.7 8.1 7.7e-10 39.2 0.4 4.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EGG19805.1 - 1.6e-25 88.3 10.3 0.00013 22.2 0.1 7.8 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 EGG19805.1 - 1.4e-23 80.4 5.9 0.00015 21.9 0.3 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EGG19805.1 - 2.3e-23 81.9 8.7 3.1e-09 36.9 0.2 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG19805.1 - 1.1e-22 80.1 5.3 2.9e-06 27.7 0.1 6.6 4 2 4 8 8 7 5 Ankyrin repeats (many copies) TPR_2 PF07719.17 EGG19805.1 - 1.1e-11 43.8 2.7 0.0089 16.1 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGG19805.1 - 3.4e-11 42.5 2.7 0.02 14.7 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGG19805.1 - 6.3e-06 26.4 0.8 0.0053 17.0 0.5 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG19805.1 - 0.00013 21.9 2.4 0.22 11.8 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG19805.1 - 0.00054 20.2 1.9 0.0021 18.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG19805.1 - 0.00058 20.0 0.4 0.0034 17.6 0.4 2.4 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 EGG19805.1 - 0.0014 18.7 1.0 0.13 12.3 0.7 3.4 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 EGG19805.1 - 0.0023 17.6 0.8 0.16 11.7 0.1 2.6 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 EGG19805.1 - 0.0039 17.8 1.6 1.1 10.0 0.7 3.0 1 1 2 3 3 3 1 Tetratricopeptide repeat NYD-SP12_N PF15015.6 EGG19805.1 - 0.014 13.8 0.0 0.024 13.0 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal TPR_14 PF13428.6 EGG19805.1 - 0.031 15.1 0.4 0.96 10.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DMA PF03474.14 EGG19805.1 - 0.033 13.8 0.1 9.6 5.9 0.0 2.6 2 0 0 2 2 2 0 DMRTA motif TPR_9 PF13371.6 EGG19805.1 - 0.054 13.6 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGG19805.1 - 0.34 10.8 5.7 3 7.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SHMT PF00464.19 EGG19806.1 - 2.1e-178 593.0 0.0 2.6e-178 592.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EGG19806.1 - 0.0019 17.6 0.0 0.014 14.7 0.0 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGG19806.1 - 0.0033 16.8 0.1 0.0062 15.9 0.1 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGG19806.1 - 0.022 13.9 0.0 0.11 11.7 0.0 2.1 1 1 0 1 1 1 0 Aminotransferase class I and II Neur PF00064.18 EGG19806.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Neuraminidase DUF5317 PF17248.2 EGG19807.1 - 1.3 9.0 6.4 3.3 7.7 2.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5317) DUF4407 PF14362.6 EGG19807.1 - 1.4 8.2 7.4 0.059 12.7 1.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) BTB_2 PF02214.22 EGG19808.1 - 4.2e-16 59.1 0.2 6.7e-16 58.4 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 EGG19808.1 - 2.5e-10 40.7 0.0 5.6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 TLD Endotoxin_N PF03945.14 EGG19809.1 - 0.00092 19.0 0.2 0.035 13.8 0.2 2.4 1 1 0 1 1 1 1 delta endotoxin, N-terminal domain Antigen_C PF16364.5 EGG19809.1 - 0.072 13.5 0.1 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Cell surface antigen C-terminus SurA_N_3 PF13624.6 EGG19809.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 SurA N-terminal domain DUF1497 PF07384.11 EGG19809.1 - 9.7 6.7 12.0 2.4 8.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1497) FNIP PF05725.12 EGG19810.1 - 2.1e-87 287.0 44.6 4.8e-16 58.6 0.1 9.6 6 2 4 11 11 11 10 FNIP Repeat Pkinase PF00069.25 EGG19810.1 - 3.3e-09 36.5 0.0 6.7e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19810.1 - 0.0083 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RasGAP PF00616.19 EGG19811.1 - 3.1e-33 115.2 0.0 3.4e-29 102.1 0.0 3.3 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EGG19811.1 - 5.1e-18 65.6 0.2 2.2e-17 63.5 0.2 2.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RE_EcoO109I PF14511.6 EGG19811.1 - 0.0069 16.0 0.3 0.7 9.4 0.0 3.0 3 0 0 3 3 3 1 Type II restriction endonuclease EcoO109I DUF764 PF05561.11 EGG19811.1 - 0.017 14.9 1.7 0.032 14.0 0.4 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF764) Cnd1 PF12717.7 EGG19811.1 - 0.16 12.0 4.7 0.66 10.0 0.6 4.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 FNIP PF05725.12 EGG19813.1 - 4.5e-155 503.7 38.4 7e-15 54.9 0.3 15.1 10 3 6 16 16 16 16 FNIP Repeat Pkinase PF00069.25 EGG19813.1 - 6.1e-21 75.0 1.4 1.2e-20 74.0 1.4 1.4 1 0 0 1 1 1 1 Protein kinase domain Phage_min_tail PF05939.13 EGG19813.1 - 6e-05 23.4 18.5 18 5.8 0.1 11.0 3 3 10 13 13 13 1 Phage minor tail protein Pkinase_Tyr PF07714.17 EGG19813.1 - 0.00015 21.1 0.0 0.018 14.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase AbiJ_NTD5 PF18865.1 EGG19813.1 - 0.019 14.8 0.7 18 5.2 0.0 5.8 5 2 3 8 8 8 0 AbiJ N-terminal domain 5 DUF4358 PF14270.6 EGG19813.1 - 0.082 13.2 6.4 0.54 10.6 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Kinase-like PF14531.6 EGG19813.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4448 PF14610.6 EGG19814.1 - 0.017 14.9 0.3 0.056 13.2 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 EGG19814.1 - 0.024 14.1 2.4 0.1 12.0 2.4 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4690 PF15756.5 EGG19815.1 - 0.00093 19.8 1.1 0.0036 17.9 0.1 2.5 2 0 0 2 2 2 1 Small Novel Rich in Cartilage Adeno_E3_CR2 PF02439.15 EGG19815.1 - 0.0099 15.6 6.4 0.032 14.0 6.4 1.9 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EGG19815.1 - 0.023 14.8 1.6 0.023 14.8 1.6 2.0 2 0 0 2 2 2 0 Podoplanin TNFR_16_TM PF18422.1 EGG19815.1 - 0.05 13.6 1.2 0.13 12.2 1.2 1.7 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain CENP-C_C PF11699.8 EGG19815.1 - 0.11 12.8 0.7 0.47 10.7 0.2 2.3 2 0 0 2 2 2 0 Mif2/CENP-C like SKG6 PF08693.10 EGG19815.1 - 0.63 9.5 6.2 2.2 7.8 6.2 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 EGG19815.1 - 0.64 10.0 4.5 1.7 8.6 4.5 1.7 1 0 0 1 1 1 0 Syndecan domain FeoB_associated PF12669.7 EGG19815.1 - 1.2 9.6 4.9 4.9 7.6 4.9 2.0 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Chordopox_A13L PF05961.11 EGG19815.1 - 1.4 9.2 3.9 3.6 7.9 3.9 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Adeno_E3_CR2 PF02439.15 EGG19816.1 - 6.3e-06 25.8 16.2 0.0019 17.9 2.4 2.7 2 0 0 2 2 2 2 Adenovirus E3 region protein CR2 DUF4690 PF15756.5 EGG19816.1 - 7.9e-06 26.4 2.1 0.19 12.4 0.7 2.9 2 0 0 2 2 2 2 Small Novel Rich in Cartilage TNFR_16_TM PF18422.1 EGG19816.1 - 0.001 19.0 6.9 0.21 11.6 0.8 2.6 2 0 0 2 2 2 2 Tumor necrosis factor receptor member 16 trans-membrane domain EphA2_TM PF14575.6 EGG19816.1 - 0.0012 19.7 4.5 1.1 10.2 0.1 2.7 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EGG19816.1 - 0.0051 16.7 11.8 0.11 12.4 1.1 2.5 2 0 0 2 2 2 2 Syndecan domain DUF4448 PF14610.6 EGG19816.1 - 0.01 15.6 0.5 2.3 7.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Yip1 PF04893.17 EGG19816.1 - 0.015 15.0 0.3 1.9 8.2 0.3 2.9 2 0 0 2 2 2 0 Yip1 domain PMP1_2 PF08114.11 EGG19816.1 - 0.041 13.6 10.7 0.2 11.4 1.3 2.8 2 0 0 2 2 2 0 ATPase proteolipid family Orf78 PF06024.12 EGG19816.1 - 0.045 14.1 0.2 13 6.2 0.0 2.8 2 0 0 2 2 2 0 Orf78 (ac78) Podoplanin PF05808.11 EGG19816.1 - 0.046 13.8 13.3 0.078 13.1 0.2 3.3 3 0 0 3 3 3 0 Podoplanin Protocadherin PF08374.11 EGG19816.1 - 0.047 13.7 2.6 1.5 8.8 0.1 2.6 2 0 0 2 2 2 0 Protocadherin Glycophorin_A PF01102.18 EGG19816.1 - 0.057 13.7 0.5 17 5.7 0.4 3.1 2 0 0 2 2 2 0 Glycophorin A DUF3290 PF11694.8 EGG19816.1 - 0.11 12.5 9.9 0.45 10.5 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) FeoB_associated PF12669.7 EGG19816.1 - 0.12 12.8 16.2 0.82 10.1 3.6 2.7 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Stevor PF17410.2 EGG19816.1 - 0.23 11.0 6.0 1.3 8.5 0.3 3.1 3 0 0 3 3 2 0 Subtelomeric Variable Open Reading frame Chordopox_A13L PF05961.11 EGG19816.1 - 0.36 11.1 13.1 3.6 7.9 3.6 2.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Insulin_TMD PF17870.1 EGG19816.1 - 0.44 10.6 10.5 4.7 7.4 1.8 2.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment CaM_bdg_C0 PF10562.9 EGG19816.1 - 0.69 10.0 7.4 9.9 6.3 3.1 2.3 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Chlam_PMP PF02415.17 EGG19816.1 - 0.83 10.3 0.0 0.65 10.6 7.1 13.7 15 3 0 15 15 11 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat SKG6 PF08693.10 EGG19816.1 - 1.5 8.3 24.8 0.28 10.6 2.4 3.4 3 0 0 3 3 3 0 Transmembrane alpha-helix domain DUF4307 PF14155.6 EGG19816.1 - 1.8 8.4 5.7 17 5.3 0.4 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Chlam_PMP PF02415.17 EGG19817.1 - 0.0094 16.4 0.1 0.0094 16.4 0.1 7.3 7 0 0 7 7 7 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Podoplanin PF05808.11 EGG19817.1 - 0.021 15.0 0.7 0.059 13.5 0.7 1.7 1 0 0 1 1 1 0 Podoplanin DUF4690 PF15756.5 EGG19817.1 - 0.1 13.2 0.2 0.5 11.0 0.1 2.3 2 0 0 2 2 2 0 Small Novel Rich in Cartilage FNIP PF05725.12 EGG19818.1 - 1.7e-183 594.7 41.3 2.6e-16 59.5 0.2 14.8 11 1 1 15 15 15 14 FNIP Repeat Phage_min_tail PF05939.13 EGG19818.1 - 9.9e-10 38.8 11.1 69 3.9 0.0 13.1 4 3 9 14 14 14 0 Phage minor tail protein AbiJ_NTD5 PF18865.1 EGG19818.1 - 0.025 14.4 3.8 1.4e+02 2.4 0.0 6.9 7 3 3 10 10 10 0 AbiJ N-terminal domain 5 Ank_4 PF13637.6 EGG19819.1 - 6.1e-28 96.8 7.7 1e-05 26.0 0.0 7.8 6 1 1 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG19819.1 - 1.2e-22 80.2 10.8 2.2e-05 24.9 0.3 5.4 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Pkinase PF00069.25 EGG19819.1 - 1.5e-19 70.4 1.4 4.2e-19 68.9 0.3 2.2 2 1 0 2 2 2 1 Protein kinase domain Ank_5 PF13857.6 EGG19819.1 - 7.1e-15 54.9 9.4 0.13 12.6 0.1 8.2 1 1 7 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19819.1 - 9.9e-11 40.9 6.5 6.6 7.7 0.0 10.8 11 1 1 12 12 12 1 Ankyrin repeat Pkinase_Tyr PF07714.17 EGG19819.1 - 2.1e-07 30.5 0.1 7.3e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase FNIP PF05725.12 EGG19819.1 - 0.00013 22.1 6.2 0.044 13.9 0.2 2.7 2 0 0 2 2 2 2 FNIP Repeat Kinase-like PF14531.6 EGG19819.1 - 0.15 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Ank PF00023.30 EGG19819.1 - 0.22 12.0 0.9 1.7e+02 2.9 0.0 5.3 6 2 2 8 8 8 0 Ankyrin repeat Ank_2 PF12796.7 EGG19820.1 - 4.2e-12 46.5 0.9 0.0013 19.2 0.0 5.3 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG19820.1 - 2.8e-11 43.7 0.5 0.12 13.0 0.0 7.0 6 1 2 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19820.1 - 9.3e-10 37.9 0.1 6.3 7.7 0.0 8.0 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 EGG19820.1 - 7.5e-07 29.3 0.1 5.6 7.4 0.2 6.3 3 2 3 6 6 6 3 Ankyrin repeats (many copies) WWE PF02825.20 EGG19821.1 - 8.2e-12 45.5 2.1 2.2e-11 44.2 2.1 1.8 1 0 0 1 1 1 1 WWE domain EF-hand_1 PF00036.32 EGG19821.1 - 4.5e-08 32.1 0.6 5.1e-05 22.5 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGG19821.1 - 7.9e-08 32.6 0.0 2e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGG19821.1 - 2.5e-07 30.1 0.1 0.032 14.2 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGG19821.1 - 2.2e-05 24.2 0.0 0.00031 20.5 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGG19821.1 - 0.0051 16.2 0.0 0.21 11.1 0.1 2.5 2 0 0 2 2 2 1 EF hand YL1 PF05764.13 EGG19821.1 - 0.012 15.7 1.9 0.012 15.7 1.9 2.2 2 0 0 2 2 1 0 YL1 nuclear protein SPARC_Ca_bdg PF10591.9 EGG19821.1 - 0.052 13.9 0.1 0.28 11.5 0.0 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGG19821.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain MGC-24 PF05283.11 EGG19821.1 - 0.37 11.2 25.3 1.8 9.0 1.8 2.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 EGG19821.1 - 0.59 10.1 47.6 1.3 9.1 6.6 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein CCDC106 PF15794.5 EGG19821.1 - 1.6 8.4 21.5 1.6 8.4 4.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Pex14_N PF04695.13 EGG19821.1 - 2.1 9.0 16.5 0.44 11.2 0.7 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.14 EGG19821.1 - 2.6 6.2 14.1 0.72 8.1 4.3 2.1 2 0 0 2 2 2 0 CDC45-like protein Dicty_REP PF05086.12 EGG19821.1 - 6.3 4.6 22.7 0.94 7.4 10.3 2.2 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.10 EGG19821.1 - 9.7 4.7 12.0 10 4.6 0.4 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Membrane_bind PF14564.6 EGG19822.1 - 1.8e-40 137.8 0.0 2.5e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Membrane binding Crystall_3 PF08964.10 EGG19822.1 - 6.2e-25 87.2 0.1 9.5e-25 86.6 0.1 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall PF00030.19 EGG19822.1 - 1.7e-05 24.9 0.1 3.2e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 Beta/Gamma crystallin AAA_2 PF07724.14 EGG19823.1 - 6.9e-59 198.8 0.0 3.5e-54 183.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGG19823.1 - 5.7e-36 122.6 0.9 5.7e-36 122.6 0.9 2.8 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 EGG19823.1 - 2.1e-28 99.4 0.0 2.4e-14 53.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGG19823.1 - 5.6e-25 87.2 2.0 2.6e-24 85.1 0.1 3.1 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 EGG19823.1 - 2.9e-20 72.1 7.0 1.8e-10 40.8 0.7 2.9 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 EGG19823.1 - 3.2e-18 66.0 1.0 1.1e-11 44.9 0.0 3.6 4 1 0 4 4 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGG19823.1 - 5.6e-12 45.7 0.1 1.4e-06 28.1 0.0 3.6 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 EGG19823.1 - 6.1e-10 39.7 12.5 5.2e-06 27.0 0.1 5.6 5 3 2 7 7 6 2 AAA ATPase domain AAA_22 PF13401.6 EGG19823.1 - 1.1e-09 38.7 1.1 0.01 16.1 0.0 5.3 4 2 0 4 4 3 2 AAA domain IstB_IS21 PF01695.17 EGG19823.1 - 1.1e-09 38.2 0.1 0.00051 19.8 0.0 3.5 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 EGG19823.1 - 1.1e-07 31.9 0.0 0.019 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 EGG19823.1 - 1.7e-06 27.6 0.1 0.0034 16.8 0.0 3.8 3 1 0 3 3 2 1 Bacterial TniB protein AAA_7 PF12775.7 EGG19823.1 - 3e-06 26.9 0.0 0.014 14.9 0.0 3.2 4 0 0 4 4 3 2 P-loop containing dynein motor region RuvB_N PF05496.12 EGG19823.1 - 1e-05 25.3 2.3 0.14 11.9 0.0 4.6 4 1 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGG19823.1 - 1.2e-05 25.9 0.1 0.16 12.5 0.0 3.7 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 EGG19823.1 - 2.6e-05 24.2 0.0 0.2 11.6 0.0 3.5 3 0 0 3 3 3 2 NACHT domain TsaE PF02367.17 EGG19823.1 - 2.7e-05 24.2 0.1 2.7 8.0 0.0 3.8 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EGG19823.1 - 4.3e-05 23.4 0.0 0.026 14.4 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGG19823.1 - 4.3e-05 23.8 0.0 0.67 10.4 0.0 3.6 3 0 0 3 3 3 2 RNA helicase AAA_23 PF13476.6 EGG19823.1 - 8.9e-05 23.1 13.9 0.022 15.2 0.0 4.1 2 2 0 2 2 1 1 AAA domain Roc PF08477.13 EGG19823.1 - 9.7e-05 22.6 0.0 0.29 11.3 0.0 3.2 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EGG19823.1 - 0.00011 22.2 1.8 1.4 8.8 0.0 4.4 4 1 1 5 5 4 1 RsgA GTPase ATPase_2 PF01637.18 EGG19823.1 - 0.00015 21.8 6.3 0.87 9.5 0.0 4.6 3 3 2 6 6 5 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EGG19823.1 - 0.00038 20.7 0.1 5 7.3 0.0 3.9 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 EGG19823.1 - 0.00038 19.9 0.0 0.91 8.9 0.0 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EGG19823.1 - 0.00042 20.8 3.7 0.85 10.1 0.0 4.7 3 2 1 4 4 4 1 ABC transporter AAA_33 PF13671.6 EGG19823.1 - 0.00052 20.2 0.0 0.8 9.9 0.0 3.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGG19823.1 - 0.00061 19.1 0.1 0.13 11.5 0.0 3.2 3 0 0 3 3 2 1 Zeta toxin AAA_25 PF13481.6 EGG19823.1 - 0.00097 18.8 1.1 0.13 11.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EGG19823.1 - 0.001 18.8 0.0 0.79 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EGG19823.1 - 0.0012 18.1 1.4 1.7 7.8 0.0 3.2 4 1 0 4 4 3 2 Protein of unknown function (DUF815) DNA_pol3_delta2 PF13177.6 EGG19823.1 - 0.0028 17.5 0.0 0.067 13.0 0.0 2.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit ResIII PF04851.15 EGG19823.1 - 0.0072 16.3 0.0 0.61 10.1 0.0 3.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EGG19823.1 - 0.0091 15.5 0.0 1.7 8.1 0.0 3.4 3 0 0 3 3 3 1 PhoH-like protein AAA_19 PF13245.6 EGG19823.1 - 0.013 15.9 1.5 0.54 10.6 0.1 3.8 3 2 1 4 4 4 0 AAA domain AAA_30 PF13604.6 EGG19823.1 - 0.015 15.0 3.6 6.5 6.4 0.0 4.4 3 2 1 4 4 4 0 AAA domain AAA_29 PF13555.6 EGG19823.1 - 0.019 14.7 0.0 11 5.8 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain T2SSE PF00437.20 EGG19823.1 - 0.022 13.8 0.0 0.088 11.9 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Torsin PF06309.11 EGG19823.1 - 0.023 14.8 0.1 1.5 8.9 0.0 3.3 4 0 0 4 4 3 0 Torsin ArsA_ATPase PF02374.15 EGG19823.1 - 0.025 13.8 0.3 7.8 5.6 0.1 3.0 3 0 0 3 3 3 0 Anion-transporting ATPase SRP54 PF00448.22 EGG19823.1 - 0.029 14.0 0.3 6.6 6.3 0.0 3.6 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain TPR_14 PF13428.6 EGG19823.1 - 0.051 14.4 1.0 20 6.3 0.0 4.4 3 0 0 3 3 2 0 Tetratricopeptide repeat Bac_DnaA PF00308.18 EGG19823.1 - 0.073 12.9 5.2 3.1 7.6 0.0 4.0 5 0 0 5 5 3 0 Bacterial dnaA protein DUF87 PF01935.17 EGG19823.1 - 0.086 12.9 9.1 1.4 8.9 0.0 4.0 4 1 0 4 4 3 0 Helicase HerA, central domain Apt1 PF10351.9 EGG19823.1 - 0.089 11.6 4.5 0.19 10.6 4.5 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain AAA_8 PF12780.7 EGG19823.1 - 0.13 11.6 0.1 18 4.5 0.1 2.8 2 1 0 2 2 2 0 P-loop containing dynein motor region D4 EMP24_GP25L PF01105.24 EGG19823.1 - 0.8 9.6 3.3 1.9 8.4 3.3 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FTA4 PF13093.6 EGG19823.1 - 0.99 9.3 11.7 2.8 7.8 11.2 1.8 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FA_desaturase PF00487.24 EGG19825.1 - 2.1e-20 73.6 21.4 2.1e-20 73.6 21.4 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EGG19825.1 - 0.00089 18.7 0.2 0.0019 17.7 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) PTPA PF03095.15 EGG19826.1 - 2e-111 372.2 0.0 2.4e-111 372.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Bombinin PF05298.11 EGG19828.1 - 0.082 12.6 1.0 0.19 11.4 1.0 1.5 1 0 0 1 1 1 0 Bombinin CobT PF06213.12 EGG19828.1 - 1.3 8.3 13.6 3.4 7.0 7.0 2.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SARAF PF06682.12 EGG19828.1 - 2.6 7.6 13.9 2.7 7.5 6.9 2.3 1 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis GvpL_GvpF PF06386.11 EGG19828.1 - 3.2 7.6 11.0 0.37 10.7 0.2 2.9 3 0 0 3 3 3 0 Gas vesicle synthesis protein GvpL/GvpF Eapp_C PF10238.9 EGG19828.1 - 3.5 7.7 17.1 1.7 8.7 5.2 2.7 3 0 0 3 3 3 0 E2F-associated phosphoprotein TFB6 PF17110.5 EGG19828.1 - 4.9 6.9 8.7 11 5.8 1.8 2.4 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH TRAP_alpha PF03896.16 EGG19828.1 - 5.3 6.2 12.7 1.3 8.2 1.4 2.5 2 1 1 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit Connexin PF00029.19 EGG19828.1 - 7.7 6.2 15.3 9.4 5.9 5.8 2.4 2 0 0 2 2 2 0 Connexin CPBP PF02517.16 EGG19829.1 - 4.6e-05 23.7 9.9 4.6e-05 23.7 9.9 3.1 2 1 1 3 3 3 1 CPBP intramembrane metalloprotease DUF3430 PF11912.8 EGG19830.1 - 9.8e-18 65.0 22.9 9.8e-18 65.0 22.9 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3430) YfaZ PF07437.11 EGG19830.1 - 0.018 14.7 0.1 0.04 13.6 0.1 1.5 1 0 0 1 1 1 0 YfaZ precursor ELMO_CED12 PF04727.13 EGG19830.1 - 0.27 11.3 5.4 0.058 13.5 1.5 2.0 2 1 0 2 2 2 0 ELMO/CED-12 family CSG2 PF16965.5 EGG19831.1 - 0.097 11.6 1.1 0.12 11.4 1.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator PNK3P PF08645.11 EGG19832.1 - 9.9e-46 155.4 0.0 1.7e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EGG19832.1 - 3.4e-18 66.2 0.0 1.8e-15 57.4 0.0 2.9 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGG19832.1 - 5.6e-06 26.0 0.4 0.021 14.3 0.0 2.5 2 0 0 2 2 2 2 Chromatin associated protein KTI12 Rho_N PF07498.12 EGG19832.1 - 6.8e-05 22.7 0.7 0.00026 20.8 0.7 2.0 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain Zeta_toxin PF06414.12 EGG19832.1 - 0.0011 18.3 0.0 0.36 10.1 0.0 2.4 1 1 1 2 2 2 2 Zeta toxin SAP PF02037.27 EGG19832.1 - 0.012 15.3 0.2 0.031 14.0 0.2 1.7 1 0 0 1 1 1 0 SAP domain BUD22 PF09073.10 EGG19832.1 - 0.013 14.9 26.1 0.018 14.4 26.1 1.1 1 0 0 1 1 1 0 BUD22 Hydrolase_like PF13242.6 EGG19832.1 - 0.07 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like MRP-S31 PF15433.6 EGG19832.1 - 0.074 12.7 11.4 0.12 12.0 11.4 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 TPP_enzyme_C PF02775.21 EGG19832.1 - 0.077 12.8 0.1 7.3 6.4 0.0 2.8 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF2486 PF10667.9 EGG19832.1 - 0.18 12.0 15.4 0.28 11.4 15.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Tub_N PF16322.5 EGG19832.1 - 0.19 12.1 24.6 0.36 11.2 24.6 1.4 1 0 0 1 1 1 0 Tubby N-terminal SDA1 PF05285.12 EGG19832.1 - 0.94 8.8 24.1 1.5 8.2 24.1 1.2 1 0 0 1 1 1 0 SDA1 Plasmodium_Vir PF05795.11 EGG19832.1 - 1.9 7.8 11.2 3.5 7.0 11.2 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4551 PF15087.6 EGG19832.1 - 3.8 6.2 15.7 5.3 5.8 15.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Mitofilin PF09731.9 EGG19832.1 - 7.3 5.3 24.7 10 4.8 24.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Cyclin_N PF00134.23 EGG19834.1 - 1.1e-19 70.4 0.9 2.1e-16 59.8 0.4 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGG19834.1 - 7.2e-08 32.5 3.1 5.1e-06 26.6 0.0 3.4 3 0 0 3 3 3 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 EGG19834.1 - 0.049 14.0 0.1 0.17 12.2 0.1 2.0 1 1 0 1 1 1 0 Cyclin C-terminal domain Helicase_C_2 PF13307.6 EGG19835.1 - 6.2e-60 202.3 1.3 1.4e-59 201.1 0.0 2.4 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 EGG19835.1 - 7.7e-44 149.4 0.1 7.7e-44 149.4 0.1 2.2 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 EGG19835.1 - 5.7e-06 26.4 7.6 0.011 15.7 0.0 3.7 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG19835.1 - 8e-05 22.5 0.4 0.04 13.7 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Vac_Fusion PF02346.16 EGG19835.1 - 0.023 14.3 0.1 0.09 12.4 0.1 2.1 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 GATase_4 PF13230.6 EGG19836.1 - 1.4e-13 50.4 0.0 1.2e-12 47.4 0.0 2.0 2 1 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EGG19836.1 - 2.7e-11 43.8 0.0 4.6e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain FNIP PF05725.12 EGG19837.1 - 9.4e-281 906.0 92.2 5.4e-15 55.3 0.0 28.5 21 4 7 30 30 30 29 FNIP Repeat Pkinase PF00069.25 EGG19837.1 - 2.2e-79 266.6 24.3 8.8e-26 90.8 1.3 5.3 5 0 0 5 5 5 5 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19837.1 - 5.9e-27 94.6 4.3 1.4e-09 37.6 0.1 5.7 5 1 0 5 5 5 3 Protein tyrosine kinase Phage_min_tail PF05939.13 EGG19837.1 - 2.2e-14 53.8 10.1 21 5.6 0.0 17.1 9 5 12 22 22 22 1 Phage minor tail protein PLD_C PF12357.8 EGG19837.1 - 0.00046 20.0 0.3 1.6 8.7 0.0 3.2 3 0 0 3 3 3 2 Phospholipase D C terminal DUF1241 PF06840.11 EGG19837.1 - 0.0026 17.4 0.0 18 5.0 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1241) ECH_2 PF16113.5 EGG19837.1 - 0.13 11.7 0.2 60 3.0 0.0 3.6 4 0 0 4 4 4 0 Enoyl-CoA hydratase/isomerase ERCC3_RAD25_C PF16203.5 EGG19837.1 - 2.6 7.2 11.4 0.66 9.1 0.1 3.8 4 0 0 4 4 4 0 ERCC3/RAD25/XPB C-terminal helicase Cyclin PF08613.11 EGG19840.1 - 4e-16 59.8 0.6 4e-16 59.8 0.6 1.9 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGG19840.1 - 0.033 13.9 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain V_ATPase_I PF01496.19 EGG19842.1 - 0.028 12.4 0.8 0.05 11.5 0.2 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family CD20 PF04103.15 EGG19842.1 - 0.046 13.8 11.5 0.39 10.8 8.6 3.0 2 1 0 2 2 2 0 CD20-like family FtsK_4TM PF13491.6 EGG19842.1 - 0.083 12.6 5.2 1.1 8.9 2.9 2.1 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE VanW PF04294.13 EGG19842.1 - 0.16 11.6 1.1 0.26 10.9 0.1 1.9 2 0 0 2 2 2 0 VanW like protein Wzy_C PF04932.15 EGG19842.1 - 0.17 11.5 6.4 0.11 12.1 1.2 2.6 1 1 1 2 2 2 0 O-Antigen ligase Tmemb_9 PF05434.11 EGG19842.1 - 0.71 9.8 14.6 1.2 9.0 0.1 3.3 2 1 1 3 3 3 0 TMEM9 S_4TM PF18159.1 EGG19842.1 - 0.89 8.8 6.1 1.1 8.5 2.6 2.4 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain DUF4834 PF16118.5 EGG19842.1 - 1.5 9.8 0.0 1.5 9.8 0.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) EDS1_EP PF18117.1 EGG19843.1 - 0.028 14.9 2.4 0.074 13.5 2.0 2.0 1 1 1 2 2 2 0 Enhanced disease susceptibility 1 protein EP domain SDA1 PF05285.12 EGG19843.1 - 0.038 13.4 8.6 0.055 12.9 8.6 1.3 1 0 0 1 1 1 0 SDA1 PBP1_TM PF14812.6 EGG19843.1 - 3.6 8.0 8.3 8.1 6.9 8.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FYVE_2 PF02318.16 EGG19844.1 - 0.0024 18.1 3.9 0.0056 16.9 3.9 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 EGG19844.1 - 0.0033 17.5 4.7 0.0092 16.1 4.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger C1_1 PF00130.22 EGG19844.1 - 0.25 11.3 9.6 0.033 14.1 5.4 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Retrotran_gag_2 PF14223.6 EGG19844.1 - 2.1 8.0 7.1 2.3 7.9 1.0 2.7 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type FNIP PF05725.12 EGG19845.1 - 1.9e-77 255.2 20.4 4.6e-15 55.5 0.0 8.4 7 2 4 11 11 11 9 FNIP Repeat Pkinase PF00069.25 EGG19845.1 - 2e-22 79.8 1.7 3.7e-22 79.0 1.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19845.1 - 1e-06 28.3 0.0 0.00053 19.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Phage_min_tail PF05939.13 EGG19845.1 - 0.00076 19.8 1.6 19 5.7 0.0 5.4 3 1 3 6 6 6 2 Phage minor tail protein DUF1769 PF08588.10 EGG19845.1 - 0.0012 19.0 0.1 4.9 7.4 0.0 5.2 6 0 0 6 6 6 1 Protein of unknown function (DUF1769) DUF1731 PF08338.11 EGG19845.1 - 0.094 12.6 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) LMSTEN PF07988.12 EGG19845.1 - 0.12 11.9 1.1 0.28 10.7 1.1 1.6 1 0 0 1 1 1 0 LMSTEN motif Glyco_hydro_39 PF01229.17 EGG19846.1 - 3.1e-103 346.0 3.0 2.2e-102 343.2 3.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 ABC_tran PF00005.27 EGG19847.1 - 2.9e-40 138.0 6.8 9e-21 74.8 0.0 3.7 4 0 0 4 4 2 2 ABC transporter FNIP PF05725.12 EGG19847.1 - 6.7e-21 74.2 23.1 1.7e-08 34.5 0.1 7.0 4 1 2 7 7 7 6 FNIP Repeat ABC_tran_Xtn PF12848.7 EGG19847.1 - 2e-18 66.2 7.6 2e-18 66.2 7.6 6.0 6 1 0 6 6 3 1 ABC transporter NB-ARC PF00931.22 EGG19847.1 - 5.1e-05 22.6 0.3 0.068 12.3 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain MMR_HSR1 PF01926.23 EGG19847.1 - 0.00017 21.7 3.0 0.014 15.5 0.0 3.5 4 0 0 4 4 4 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EGG19847.1 - 0.00027 20.9 17.0 0.14 12.0 0.3 5.4 5 1 0 6 6 6 3 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 EGG19847.1 - 0.00044 20.6 0.0 0.23 11.9 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.6 EGG19847.1 - 0.0012 19.2 0.0 0.3 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EGG19847.1 - 0.0019 17.9 0.6 0.16 11.8 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG19847.1 - 0.0036 17.2 9.0 0.18 11.7 0.0 3.5 4 0 0 4 4 3 2 RsgA GTPase AAA_22 PF13401.6 EGG19847.1 - 0.0041 17.4 0.0 2.2 8.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 EGG19847.1 - 0.0048 17.1 0.1 1.3 9.3 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EGG19847.1 - 0.0053 16.7 0.0 5 7.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_7 PF12775.7 EGG19847.1 - 0.0067 16.0 0.1 1.7 8.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 EGG19847.1 - 0.0072 16.5 0.0 4.3 7.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGG19847.1 - 0.021 14.9 0.0 0.94 9.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGG19847.1 - 0.035 14.5 0.0 14 6.1 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EGG19847.1 - 0.32 11.1 0.0 0.32 11.1 0.0 4.7 5 0 0 5 5 5 0 Helicase HerA, central domain AAA_23 PF13476.6 EGG19847.1 - 3.8 7.9 0.0 3.8 7.9 0.0 6.1 5 1 1 6 6 4 0 AAA domain Cpn60_TCP1 PF00118.24 EGG19848.1 - 4.7e-90 302.6 0.8 2e-47 161.9 0.2 2.2 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Luteo_Vpg PF01659.16 EGG19848.1 - 0.055 13.8 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein FNIP PF05725.12 EGG19849.1 - 2.9e-44 149.0 16.6 2.6e-15 56.3 0.1 5.6 3 2 2 5 5 5 5 FNIP Repeat Pkinase PF00069.25 EGG19849.1 - 0.0029 17.0 2.5 0.03 13.7 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain adh_short PF00106.25 EGG19850.1 - 7.6e-52 175.6 0.1 1e-51 175.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG19850.1 - 1.3e-35 123.1 0.0 1.6e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG19850.1 - 6.8e-07 29.4 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGG19850.1 - 9.9e-06 25.6 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EGG19850.1 - 0.00031 20.2 0.1 0.01 15.3 0.1 2.2 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EGG19850.1 - 0.0011 18.6 0.1 0.002 17.7 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EGG19850.1 - 0.0054 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGG19850.1 - 0.081 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF3337 PF11816.8 EGG19850.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) ABC_membrane PF00664.23 EGG19851.1 - 1e-129 432.0 17.8 3.5e-67 227.0 5.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGG19851.1 - 1.8e-68 229.3 0.1 3.3e-33 115.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGG19851.1 - 7.4e-13 48.4 1.2 1.9e-05 24.2 0.1 4.0 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EGG19851.1 - 1.2e-07 30.9 0.2 0.0033 16.3 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 EGG19851.1 - 1.2e-06 28.8 0.0 0.016 15.5 0.0 2.9 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGG19851.1 - 9e-06 25.3 0.4 0.11 12.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG19851.1 - 0.00012 22.1 0.0 0.53 10.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF815 PF05673.13 EGG19851.1 - 0.0013 17.9 0.0 0.82 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_16 PF13191.6 EGG19851.1 - 0.0021 18.5 0.2 2.9 8.3 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EGG19851.1 - 0.0024 18.3 1.4 1.1 9.7 0.0 3.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGG19851.1 - 0.003 17.1 0.0 2 7.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 EGG19851.1 - 0.0035 17.5 3.7 6.2 7.1 0.2 4.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EGG19851.1 - 0.0045 16.7 0.0 0.63 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGG19851.1 - 0.0059 15.9 0.1 3.3 6.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_15 PF13175.6 EGG19851.1 - 0.023 14.4 0.2 5 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 EGG19851.1 - 0.033 14.0 0.2 9.6 5.9 0.1 3.4 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 EGG19851.1 - 0.042 14.1 0.3 8.7 6.6 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EGG19851.1 - 0.055 13.2 0.3 12 5.5 0.0 3.0 2 2 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGG19851.1 - 0.076 12.6 0.1 2 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGG19851.1 - 0.087 12.8 0.6 22 5.1 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 EGG19851.1 - 0.15 11.2 0.0 2.4 7.3 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit CDC45 PF02724.14 EGG19851.1 - 0.17 10.1 0.8 0.31 9.3 0.8 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF4133 PF13571.6 EGG19851.1 - 3.3 8.1 8.8 0.22 11.9 0.5 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4133) Ank_2 PF12796.7 EGG19852.1 - 2.6e-12 47.1 6.4 0.17 12.5 0.0 6.0 3 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG19852.1 - 3.7e-06 26.8 2.2 80 4.3 0.0 7.5 8 0 0 8 8 8 2 Ankyrin repeat PAP_assoc PF03828.19 EGG19854.1 - 6.8e-23 80.7 7.8 2.8e-11 43.4 0.9 2.9 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGG19854.1 - 0.00011 22.4 16.8 0.0033 17.7 0.1 5.9 6 0 0 6 6 6 2 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.11 EGG19854.1 - 0.016 15.4 0.0 3.6 7.9 0.0 3.1 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain Polbeta PF18765.1 EGG19854.1 - 0.45 10.6 10.6 0.43 10.7 0.1 4.8 5 0 0 5 5 5 0 Polymerase beta, Nucleotidyltransferase PI31_Prot_N PF11566.8 EGG19854.1 - 1.1 9.0 6.9 0.42 10.4 1.3 3.2 2 0 0 2 2 2 0 PI31 proteasome regulator N-terminal DUF3858 PF12970.7 EGG19854.1 - 8.1 6.5 10.6 2.4 8.2 0.4 3.4 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3858) AAA_12 PF13087.6 EGG19855.1 - 7.1e-56 189.0 0.7 7.1e-56 189.0 0.7 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EGG19855.1 - 1.2e-49 169.5 3.8 1.1e-23 84.4 0.1 3.7 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 EGG19855.1 - 1.1e-13 51.8 0.0 2.7e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG19855.1 - 2.2e-13 50.4 0.0 5.1e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain PAP_assoc PF03828.19 EGG19855.1 - 2.5e-11 43.6 2.1 4.9e-11 42.7 0.7 2.4 2 0 0 2 2 2 1 Cid1 family poly A polymerase Viral_helicase1 PF01443.18 EGG19855.1 - 4.9e-08 33.0 0.4 0.28 10.9 0.0 4.6 5 0 0 5 5 5 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGG19855.1 - 9.4e-05 22.7 0.2 0.00039 20.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 EGG19855.1 - 0.00014 21.9 0.0 0.0016 18.5 0.0 2.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NTP_transf_2 PF01909.23 EGG19855.1 - 0.0002 21.6 0.3 0.0034 17.6 0.1 3.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain PhoH PF02562.16 EGG19855.1 - 0.0002 20.9 0.0 0.0015 18.0 0.0 2.1 1 1 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.21 EGG19855.1 - 0.0025 17.4 0.0 0.0025 17.4 0.0 3.8 3 2 1 4 4 4 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 EGG19855.1 - 0.0048 17.3 0.1 0.03 14.8 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGG19855.1 - 0.009 15.6 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG19855.1 - 0.0097 16.3 0.0 0.04 14.3 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGG19855.1 - 0.034 14.7 0.1 0.46 11.0 0.0 3.1 3 1 0 3 3 2 0 AAA domain T2SSE PF00437.20 EGG19855.1 - 0.036 13.1 0.1 0.088 11.8 0.1 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Polbeta PF18765.1 EGG19855.1 - 0.042 13.9 0.9 0.24 11.5 0.1 2.8 2 0 0 2 2 1 0 Polymerase beta, Nucleotidyltransferase AAA_5 PF07728.14 EGG19855.1 - 0.045 13.8 0.0 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 EGG19855.1 - 0.052 12.8 0.7 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 EGG19855.1 - 0.12 12.1 0.0 0.38 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvrD_C_2 PF13538.6 EGG19855.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DEAD PF00270.29 EGG19855.1 - 0.21 11.3 2.0 1.9 8.2 0.1 2.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase Laminin_EGF PF00053.24 EGG19856.1 - 2.5e-05 24.3 19.2 0.011 15.9 3.1 3.3 3 0 0 3 3 3 2 Laminin EGF domain DUF5050 PF16472.5 EGG19856.1 - 0.024 13.9 3.1 0.24 10.6 3.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5050) EGF_2 PF07974.13 EGG19856.1 - 2.1 8.8 15.6 11 6.5 1.6 3.2 2 0 0 2 2 2 0 EGF-like domain Dimer_Tnp_hAT PF05699.14 EGG19857.1 - 9.1e-16 57.4 0.5 1.2e-15 57.0 0.5 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C6H2 PF15801.5 EGG19857.1 - 0.098 13.0 1.3 0.098 13.0 1.3 2.2 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding FNIP PF05725.12 EGG19858.1 - 4.7e-199 644.4 51.2 7.1e-16 58.1 0.1 16.5 6 4 6 17 17 17 17 FNIP Repeat Pkinase PF00069.25 EGG19858.1 - 1.3e-20 73.9 1.2 2.7e-20 72.9 1.2 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19858.1 - 4.2e-06 26.2 0.0 0.00033 20.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase DUF1731 PF08338.11 EGG19858.1 - 0.082 12.8 0.1 6 6.8 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1731) baeRF_family10 PF18854.1 EGG19858.1 - 0.086 13.1 0.0 2.1e+02 2.1 0.0 5.2 5 1 1 7 7 7 0 Bacterial archaeo-eukaryotic release factor family 10 AAA_12 PF13087.6 EGG19861.1 - 3.2e-57 193.4 0.2 9.1e-57 191.9 0.2 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGG19861.1 - 1.1e-46 159.7 0.1 1.3e-23 84.1 0.0 5.2 4 2 1 5 5 5 2 AAA domain PAP_assoc PF03828.19 EGG19861.1 - 4.1e-13 49.3 0.4 1.2e-12 47.8 0.4 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase AAA_30 PF13604.6 EGG19861.1 - 6.7e-12 45.5 0.0 1.6e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG19861.1 - 1.5e-10 41.6 0.0 4.8e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGG19861.1 - 1.2e-06 28.4 0.0 0.57 9.9 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EGG19861.1 - 0.0033 16.9 0.1 1.6 8.1 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein Polbeta PF18765.1 EGG19861.1 - 0.0049 16.9 0.2 0.12 12.5 0.0 3.0 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase AAA_22 PF13401.6 EGG19861.1 - 0.0082 16.4 0.0 0.044 14.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain NTP_transf_2 PF01909.23 EGG19861.1 - 0.018 15.3 0.0 0.069 13.4 0.0 2.0 1 0 0 1 1 1 0 Nucleotidyltransferase domain ResIII PF04851.15 EGG19861.1 - 0.019 15.0 0.1 0.15 12.1 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EGG19861.1 - 0.019 14.5 0.0 0.056 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGG19861.1 - 0.026 14.9 0.3 0.34 11.3 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EGG19861.1 - 0.045 12.8 0.0 1 8.3 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 EGG19861.1 - 0.052 13.9 0.2 0.21 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain KcnmB2_inactiv PF09303.10 EGG19861.1 - 0.073 12.9 0.9 8.6 6.3 0.1 2.7 2 0 0 2 2 2 0 KCNMB2, ball and chain domain ABC_tran PF00005.27 EGG19861.1 - 0.081 13.4 0.0 0.44 11.0 0.0 2.4 1 0 0 1 1 1 0 ABC transporter MADF_DNA_bdg PF10545.9 EGG19861.1 - 0.21 11.9 1.9 0.53 10.6 0.1 2.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4611 PF15387.6 EGG19861.1 - 1.1 9.5 7.4 4.1 7.7 7.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zinc_ribbon_12 PF11331.8 EGG19862.1 - 0.95 9.3 3.8 6.1 6.7 3.8 2.3 1 1 0 1 1 1 0 Probable zinc-ribbon domain Dicty_REP PF05086.12 EGG19863.1 - 0.64 7.9 11.2 0.7 7.8 11.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Spt20 PF12090.8 EGG19863.1 - 1 8.9 32.6 1.1 8.8 32.6 1.0 1 0 0 1 1 1 0 Spt20 family DUF775 PF05603.12 EGG19863.1 - 1.5 8.3 13.1 1.6 8.2 13.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF775) EIIBC-GUT_N PF03612.14 EGG19863.1 - 1.8 8.3 8.9 1.8 8.3 8.9 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Orf78 PF06024.12 EGG19863.1 - 1.8 8.9 6.0 1.9 8.8 6.0 1.0 1 0 0 1 1 1 0 Orf78 (ac78) DUF2722 PF10846.8 EGG19863.1 - 2 7.3 26.2 2 7.3 26.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF3464 PF11947.8 EGG19863.1 - 2.1 8.1 8.6 2.1 8.1 8.6 1.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 FlaG PF03646.15 EGG19863.1 - 2.6 8.2 15.5 2.9 8.1 15.5 1.1 1 0 0 1 1 1 0 FlaG protein DUF4834 PF16118.5 EGG19863.1 - 2.7 9.0 12.4 2.9 8.9 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 EGG19863.1 - 3.6 6.2 10.0 3.9 6.1 10.0 1.0 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 EGG19863.1 - 3.9 8.1 18.7 3.8 8.1 18.7 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DivIC PF04977.15 EGG19863.1 - 4.5 7.1 16.8 5.1 6.9 16.8 1.1 1 0 0 1 1 1 0 Septum formation initiator Renin_r PF07850.14 EGG19863.1 - 5 7.8 5.7 5.4 7.7 5.7 1.1 1 0 0 1 1 1 0 Renin receptor-like protein Conotoxin PF02950.17 EGG19863.1 - 5.1 8.2 8.4 5.9 8.0 8.4 1.1 1 0 0 1 1 1 0 Conotoxin Med15 PF09606.10 EGG19863.1 - 5.7 5.5 25.1 5.3 5.6 25.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.14 EGG19863.1 - 7.9 6.4 15.9 7.9 6.4 15.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ORC6 PF05460.13 EGG19864.1 - 0.00013 21.4 20.5 0.00026 20.4 0.0 3.3 2 1 0 3 3 3 1 Origin recognition complex subunit 6 (ORC6) SKG6 PF08693.10 EGG19864.1 - 0.016 14.6 2.9 0.03 13.8 2.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CDC24_OB1 PF17246.2 EGG19865.1 - 3.1e-09 37.0 0.2 3.3e-09 36.9 0.2 1.0 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 TLD PF07534.16 EGG19866.1 - 4.1e-18 65.9 2.2 7.8e-18 65.0 2.2 1.4 1 0 0 1 1 1 1 TLD BTB_2 PF02214.22 EGG19866.1 - 7.3e-08 32.7 1.2 5.6e-07 29.8 0.0 2.8 2 1 1 3 3 3 1 BTB/POZ domain Spc24 PF08286.11 EGG19866.1 - 0.039 14.2 0.9 0.039 14.2 0.9 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2443 PF10398.9 EGG19866.1 - 0.053 13.6 0.8 0.15 12.2 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) DUF4140 PF13600.6 EGG19866.1 - 0.08 13.4 0.8 0.16 12.4 0.8 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1657 PF07870.11 EGG19866.1 - 0.16 11.9 1.6 0.72 9.8 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) DUF4472 PF14739.6 EGG19866.1 - 0.21 12.3 5.0 1 10.1 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) TTR-52 PF01060.23 EGG19867.1 - 0.047 14.4 0.1 0.25 12.1 0.0 2.3 2 0 0 2 2 2 0 Transthyretin-like family Ank_3 PF13606.6 EGG19867.1 - 0.051 14.2 0.4 1.9e+02 3.2 0.0 4.2 3 0 0 3 3 3 0 Ankyrin repeat FokI_N PF02981.15 EGG19867.1 - 0.053 13.7 0.1 0.19 11.9 0.1 2.0 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain ASH PF15780.5 EGG19867.1 - 0.073 13.3 1.3 0.19 11.9 0.2 2.4 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1398 PF07166.11 EGG19867.1 - 1.4 8.9 5.2 1 9.5 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1398) DUF913 PF06025.12 EGG19867.1 - 8.4 5.3 10.5 9.6 5.1 6.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) COX6B PF02297.17 EGG19868.1 - 4.1e-14 52.6 6.1 6e-14 52.0 6.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 EGG19868.1 - 0.00024 21.1 6.7 0.00053 20.0 6.7 1.6 1 0 0 1 1 1 1 CHCH domain MoaC PF01967.21 EGG19869.1 - 1.5e-49 167.6 1.9 1.8e-49 167.3 1.9 1.1 1 0 0 1 1 1 1 MoaC family DUF4840 PF16128.5 EGG19869.1 - 0.00097 19.2 0.1 0.0013 18.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4840) PH_4 PF15404.6 EGG19870.1 - 0.16 11.8 8.2 0.4 10.4 8.2 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain CDC45 PF02724.14 EGG19870.1 - 8.9 4.5 12.7 13 3.9 12.5 1.4 1 1 0 1 1 1 0 CDC45-like protein Mob_synth_C PF06463.13 EGG19871.1 - 1.7e-39 134.7 0.0 3.3e-39 133.7 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EGG19871.1 - 8.1e-30 104.4 0.1 2.4e-29 102.8 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 EGG19871.1 - 4.8e-09 36.6 0.0 1.3e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EGG19871.1 - 1.4e-05 25.2 0.0 4.5e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain AhpC-TSA PF00578.21 EGG19871.1 - 0.057 13.3 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 AhpC/TSA family CDC24_OB3 PF17244.2 EGG19872.1 - 4.8e-43 147.5 0.5 1.6e-42 145.7 0.5 2.0 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 3 CDC24_OB1 PF17246.2 EGG19872.1 - 5e-23 81.5 4.4 5e-23 81.5 4.4 2.6 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 1 NST1 PF13945.6 EGG19872.1 - 0.28 11.3 3.6 0.64 10.1 0.7 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF3439 PF11921.8 EGG19872.1 - 2.3 8.2 10.4 6.4 6.8 10.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Rtt106 PF08512.12 EGG19873.1 - 1.4e-26 92.8 0.2 6.6e-24 84.2 0.1 2.8 2 1 1 3 3 3 2 Histone chaperone Rttp106-like POB3_N PF17292.2 EGG19873.1 - 3.9e-26 91.3 1.2 2.1e-22 79.3 0.1 3.5 3 1 0 3 3 3 2 POB3-like N-terminal PH domain SSrecog PF03531.14 EGG19873.1 - 9.2e-20 70.3 1.4 1.8e-18 66.2 0.3 2.8 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) GAPES3 PF17154.4 EGG19873.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Rrp44_CSD1 PF17216.3 EGG19873.1 - 0.5 10.1 3.7 1.1 9.0 3.7 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain NOA36 PF06524.12 EGG19873.1 - 1.7 7.9 10.2 3.4 6.9 10.2 1.5 1 0 0 1 1 1 0 NOA36 protein NKAP PF15692.5 EGG19873.1 - 2.6 8.8 12.3 6.5 7.6 12.3 1.7 1 0 0 1 1 1 0 NF-kappa-B-activating protein BUD22 PF09073.10 EGG19873.1 - 4.9 6.4 21.8 0.05 12.9 14.1 1.5 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.14 EGG19873.1 - 6.9 4.8 13.3 11 4.2 13.3 1.3 1 0 0 1 1 1 0 CDC45-like protein PPR_2 PF13041.6 EGG19875.1 - 4.1e-07 30.1 0.4 5.6 7.2 0.0 5.0 5 0 0 5 5 5 3 PPR repeat family PPR PF01535.20 EGG19875.1 - 0.00017 21.6 1.9 5.5 7.5 0.0 5.4 6 0 0 6 6 6 2 PPR repeat TPR_14 PF13428.6 EGG19875.1 - 0.0028 18.4 0.6 0.59 11.1 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat FAM220 PF15487.6 EGG19875.1 - 3.3 7.2 12.7 7 6.2 12.7 1.5 1 0 0 1 1 1 0 FAM220 family SPX PF03105.19 EGG19875.1 - 5.7 6.7 22.7 5.9 6.7 19.9 2.0 2 0 0 2 2 2 0 SPX domain His_Phos_1 PF00300.22 EGG19876.1 - 6.8e-32 110.7 0.0 1.9e-26 93.0 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) FNIP PF05725.12 EGG19877.1 - 6.5e-121 394.3 20.4 1.5e-15 57.1 0.2 9.7 8 1 1 9 9 9 9 FNIP Repeat Phage_min_tail PF05939.13 EGG19877.1 - 6.6e-06 26.5 5.3 33 4.9 0.0 9.0 4 3 7 11 11 11 1 Phage minor tail protein AbiJ_NTD5 PF18865.1 EGG19877.1 - 0.0005 19.8 0.5 26 4.7 0.0 6.4 8 1 2 10 10 10 1 AbiJ N-terminal domain 5 DUF1769 PF08588.10 EGG19877.1 - 0.00075 19.7 7.1 8.2 6.7 0.1 7.0 6 3 3 9 9 9 1 Protein of unknown function (DUF1769) CPBP PF02517.16 EGG19877.1 - 0.0073 16.7 0.4 3.2 8.2 0.1 4.5 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease FNIP PF05725.12 EGG19878.1 - 4.2e-14 52.4 6.3 5.6e-10 39.2 1.2 3.0 2 1 0 2 2 2 2 FNIP Repeat Pkinase PF00069.25 EGG19878.1 - 4e-06 26.4 0.0 7.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Biopterin_H PF00351.21 EGG19879.1 - 6.1e-166 551.4 0.0 7.4e-166 551.2 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 EGG19879.1 - 8.2e-07 28.7 0.0 2.1e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 ACT domain ACT_4 PF13291.6 EGG19879.1 - 0.0027 18.3 0.1 0.013 16.1 0.0 2.1 2 0 0 2 2 2 1 ACT domain GRAS PF03514.14 EGG19879.1 - 0.19 10.6 0.0 2.9 6.7 0.0 2.1 2 0 0 2 2 2 0 GRAS domain family RhoGAP PF00620.27 EGG19880.1 - 9e-39 132.7 0.1 9e-39 132.7 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 EGG19880.1 - 3e-23 82.3 2.7 1.2e-21 77.2 0.7 2.6 2 1 0 2 2 2 1 PH domain BAR_3 PF16746.5 EGG19880.1 - 2.6e-06 27.3 1.8 2.6e-06 27.3 1.8 2.4 1 1 1 2 2 2 1 BAR domain of APPL family PH_11 PF15413.6 EGG19880.1 - 0.0092 16.4 3.4 0.0092 16.4 3.4 3.1 3 1 0 3 3 3 1 Pleckstrin homology domain ALMT PF11744.8 EGG19880.1 - 0.13 11.0 9.7 0.23 10.2 9.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter F_actin_cap_B PF01115.17 EGG19882.1 - 1.2e-105 352.4 0.0 1.4e-105 352.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 EGG19882.1 - 0.015 14.8 0.2 0.032 13.7 0.2 1.8 1 1 0 1 1 1 0 F-actin capping protein alpha subunit SR-25 PF10500.9 EGG19883.1 - 0.0052 16.4 32.4 0.0052 16.4 32.4 3.1 1 1 2 3 3 3 2 Nuclear RNA-splicing-associated protein S1 PF00575.23 EGG19883.1 - 0.022 15.1 0.3 0.022 15.1 0.3 2.4 2 0 0 2 2 2 0 S1 RNA binding domain ATP-synt_S1 PF05827.12 EGG19884.1 - 1.1e-06 28.5 0.1 3.4e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) PGG PF13962.6 EGG19884.1 - 0.042 13.7 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function zf-C3HC4_2 PF13923.6 EGG19885.1 - 7.1e-11 41.8 10.3 1.2e-10 41.1 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG19885.1 - 1.9e-09 37.7 9.5 3.4e-09 36.9 9.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG19885.1 - 2.7e-09 36.9 3.2 2.7e-09 36.9 3.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG19885.1 - 5.1e-09 35.9 9.7 8.1e-09 35.3 9.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGG19885.1 - 9.4e-09 35.0 10.3 1.6e-08 34.3 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG19885.1 - 2.2e-08 33.8 8.8 3.2e-08 33.3 8.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG19885.1 - 6.1e-07 29.2 8.2 4.9e-06 26.3 7.9 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGG19885.1 - 3.9e-06 26.9 6.1 1.4e-05 25.2 6.4 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGG19885.1 - 7.3e-05 23.0 7.6 7.3e-05 23.0 7.6 2.1 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 EGG19885.1 - 0.001 18.9 8.6 0.0025 17.6 8.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EGG19885.1 - 0.0035 17.1 7.1 0.0091 15.8 7.1 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain YL1 PF05764.13 EGG19885.1 - 0.012 15.7 14.4 0.21 11.7 6.5 2.2 2 0 0 2 2 2 0 YL1 nuclear protein zf-RING_6 PF14835.6 EGG19885.1 - 0.013 15.4 2.9 0.025 14.4 2.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zinc-ribbons_6 PF07191.12 EGG19885.1 - 0.04 13.9 7.1 0.077 13.0 7.1 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-Di19 PF05605.12 EGG19885.1 - 0.17 12.2 7.6 4.7 7.6 7.4 2.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding BUD22 PF09073.10 EGG19885.1 - 0.19 11.1 19.1 0.055 12.8 1.2 2.1 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 EGG19885.1 - 0.22 10.9 20.0 0.52 9.7 3.9 2.2 2 0 0 2 2 2 0 SDA1 zf-P11 PF03854.14 EGG19885.1 - 0.3 10.8 4.9 0.62 9.8 4.9 1.5 1 0 0 1 1 1 0 P-11 zinc finger Rad50_zn_hook PF04423.14 EGG19885.1 - 0.4 10.5 3.7 0.63 9.9 0.0 2.6 3 0 0 3 3 2 0 Rad50 zinc hook motif zf-piccolo PF05715.13 EGG19885.1 - 0.58 10.3 7.7 4.2 7.6 2.7 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger DZR PF12773.7 EGG19885.1 - 0.61 10.1 7.8 1.5 8.9 7.8 1.6 1 1 0 1 1 1 0 Double zinc ribbon Utp14 PF04615.13 EGG19885.1 - 3.6 6.1 11.1 2.3 6.7 0.9 2.3 2 0 0 2 2 2 0 Utp14 protein DUF4637 PF15470.6 EGG19885.1 - 4 7.1 14.7 0.24 11.1 2.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) CPSF100_C PF13299.6 EGG19885.1 - 4.2 7.5 5.2 4.3 7.5 0.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal LegC3_N PF18654.1 EGG19885.1 - 5.8 6.1 6.7 2.4 7.3 0.2 2.3 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain RMI2 PF16100.5 EGG19886.1 - 1.2e-08 34.8 1.4 5.3e-05 23.0 0.0 2.8 2 1 1 3 3 3 2 RecQ-mediated genome instability protein 2 tRNA_anti-codon PF01336.25 EGG19886.1 - 0.012 15.6 0.6 0.12 12.3 0.0 2.7 3 1 0 3 3 3 0 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EGG19886.1 - 0.094 12.9 0.1 2.6 8.3 0.1 2.5 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain Neur_chan_memb PF02932.16 EGG19886.1 - 0.99 9.4 6.8 1.5 8.8 6.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop14 PF04147.12 EGG19886.1 - 2.9 6.0 38.3 3.7 5.6 38.3 1.1 1 0 0 1 1 1 0 Nop14-like family Band_7 PF01145.25 EGG19887.1 - 0.044 13.8 0.3 0.094 12.7 0.1 1.5 2 0 0 2 2 2 0 SPFH domain / Band 7 family Myotub-related PF06602.14 EGG19888.1 - 1.8e-121 405.3 0.3 3.8e-121 404.3 0.3 1.5 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EGG19888.1 - 0.00074 19.6 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EGG19888.1 - 0.0019 18.0 0.0 0.006 16.4 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG19888.1 - 0.017 14.7 0.0 0.017 14.7 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DUF1970 PF09301.10 EGG19888.1 - 0.41 10.9 2.2 1.2 9.4 2.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) SR-25 PF10500.9 EGG19888.1 - 5.6 6.5 62.2 0.015 14.9 11.3 4.3 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein TMEM237 PF15383.6 EGG19888.1 - 6.5 5.8 7.0 3.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Transmembrane protein 237 BTB_2 PF02214.22 EGG19890.1 - 1e-20 73.9 0.1 2.1e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 EGG19890.1 - 6e-17 62.2 0.2 1.4e-16 61.0 0.2 1.6 1 0 0 1 1 1 1 TLD BTB_2 PF02214.22 EGG19891.1 - 2.4e-20 72.7 0.1 5.1e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 EGG19891.1 - 1.7e-19 70.5 2.3 3.3e-19 69.5 2.3 1.5 1 0 0 1 1 1 1 TLD BTB_2 PF02214.22 EGG19892.1 - 2.1e-19 69.7 0.0 5.2e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 EGG19892.1 - 2.4e-06 27.8 0.1 3e-05 24.3 0.1 2.4 1 1 1 2 2 2 1 TLD BTB_2 PF02214.22 EGG19893.1 - 1.7e-19 70.0 0.1 6.7e-19 68.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain TLD PF07534.16 EGG19893.1 - 2e-15 57.2 0.3 5e-14 52.7 0.1 2.4 1 1 1 2 2 2 1 TLD Complex1_51K PF01512.17 EGG19894.1 - 7.6e-48 162.2 0.0 1.1e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EGG19894.1 - 3.8e-30 103.8 0.0 7.9e-30 102.8 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EGG19894.1 - 3.4e-08 33.2 0.0 8.9e-08 31.9 0.0 1.8 1 0 0 1 1 1 1 SLBB domain FA_desaturase PF00487.24 EGG19896.1 - 6e-37 127.9 10.5 2e-36 126.1 10.0 1.9 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 EGG19896.1 - 4.7e-24 84.3 0.3 1.7e-23 82.5 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.6 EGG19896.1 - 0.019 15.1 0.3 0.041 14.0 0.3 1.5 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Dicty_CAR PF05462.11 EGG19897.1 - 8.9e-112 373.1 15.6 8.9e-112 373.1 15.6 1.5 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Frizzled PF01534.17 EGG19897.1 - 9.1e-06 24.9 4.3 1.3e-05 24.4 4.3 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 EGG19897.1 - 7.9e-05 22.1 6.8 0.00012 21.5 6.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) BLM_N PF16202.5 EGG19897.1 - 0.024 13.8 1.1 0.031 13.4 1.1 1.1 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein Ocular_alb PF02101.15 EGG19897.1 - 0.043 12.7 5.2 0.061 12.2 5.2 1.1 1 0 0 1 1 1 0 Ocular albinism type 1 protein Git3 PF11710.8 EGG19897.1 - 5.8 6.6 15.8 0.059 13.1 5.6 2.2 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Ku_PK_bind PF08785.11 EGG19898.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Ku C terminal domain like ASH PF15780.5 EGG19899.1 - 2.7e-22 78.8 0.0 3.6e-09 36.7 0.0 4.8 4 0 0 4 4 4 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EGG19899.1 - 0.0019 18.3 0.0 0.065 13.4 0.0 2.7 2 0 0 2 2 2 1 Flagellar-associated PapD-like FNIP PF05725.12 EGG19900.1 - 5.2e-22 77.8 10.3 4e-11 42.9 0.1 5.1 3 2 2 5 5 5 4 FNIP Repeat FAM91_C PF14648.6 EGG19901.1 - 1.2e-151 505.4 3.5 1.6e-151 505.0 3.5 1.2 1 0 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.6 EGG19901.1 - 3.1e-109 365.0 1.3 6.2e-109 364.0 1.3 1.5 1 0 0 1 1 1 1 FAM91 N-terminus Kelch_1 PF01344.25 EGG19902.1 - 5.8e-38 128.2 18.3 5.6e-09 35.4 0.4 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EGG19902.1 - 5.1e-35 118.6 20.7 3.9e-09 36.5 0.9 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EGG19902.1 - 2.4e-34 116.8 23.0 3.6e-08 33.2 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGG19902.1 - 9.6e-34 115.0 8.4 2.4e-07 30.9 0.1 7.4 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_4 PF13418.6 EGG19902.1 - 1.4e-22 79.4 12.4 3e-05 23.9 1.2 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 EGG19902.1 - 7e-19 67.0 25.0 3.9e-06 26.6 0.1 6.6 5 1 1 6 6 6 6 Kelch motif F-box-like PF12937.7 EGG19902.1 - 4.9e-11 42.3 0.5 1.4e-10 40.9 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG19902.1 - 6.5e-11 41.8 0.7 1.6e-10 40.6 0.7 1.7 1 0 0 1 1 1 1 F-box domain RAG2 PF03089.14 EGG19902.1 - 0.0063 15.5 1.7 0.03 13.3 0.0 2.9 3 1 0 4 4 4 1 Recombination activating protein 2 F-box_4 PF15966.5 EGG19902.1 - 0.029 14.3 0.0 0.029 14.3 0.0 2.4 2 1 0 2 2 2 0 F-box PIP49_N PF14875.6 EGG19902.1 - 0.047 13.6 0.4 0.047 13.6 0.4 2.2 2 1 0 2 2 2 0 N-term cysteine-rich ER, FAM69 SUIM_assoc PF16619.5 EGG19902.1 - 1.5 9.0 10.4 0.41 10.7 4.4 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Dus PF01207.17 EGG19907.1 - 2.3e-48 164.9 0.6 3.8e-48 164.2 0.5 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) EGF_2 PF07974.13 EGG19908.1 - 0.00032 21.0 28.2 0.094 13.1 9.9 2.7 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 EGG19908.1 - 0.033 14.8 24.5 0.74 10.5 9.0 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF PDZ PF00595.24 EGG19908.1 - 0.18 12.1 0.1 41 4.6 0.0 2.6 2 0 0 2 2 2 0 PDZ domain DUF3042 PF11240.8 EGG19908.1 - 0.26 11.3 6.5 0.28 11.2 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF3844 PF12955.7 EGG19908.1 - 1.6 8.9 15.0 6.9 6.9 4.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) Metallothio_5 PF02067.15 EGG19908.1 - 6 7.1 25.3 6.4 7.0 7.8 2.7 2 0 0 2 2 2 0 Metallothionein family 5 Pribosyltran_N PF13793.6 EGG19909.1 - 9e-39 132.0 0.1 2.6e-38 130.5 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGG19909.1 - 1.1e-31 110.4 1.5 9.2e-31 107.3 0.7 2.2 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGG19909.1 - 3.3e-06 26.7 0.6 1.1e-05 25.0 0.6 1.9 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Longin_2 PF18639.1 EGG19909.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Yeast longin domain Fer2_BFD PF04324.15 EGG19909.1 - 0.12 12.7 0.7 0.4 11.1 0.0 2.2 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Sod_Cu PF00080.20 EGG19910.1 - 2.4e-49 167.2 10.1 2.4e-31 108.8 2.1 2.1 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) DUF4470 PF14737.6 EGG19911.1 - 2e-07 31.1 0.1 1.3e-05 25.3 0.0 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 EGG19911.1 - 2e-05 24.2 0.0 0.00012 21.7 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 EGG19911.1 - 0.00041 20.1 0.4 0.01 15.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG19911.1 - 0.00043 20.2 0.0 0.022 14.8 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG19911.1 - 0.00061 20.0 0.0 0.83 10.0 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG19911.1 - 0.0026 17.9 0.8 0.68 10.3 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG19911.1 - 0.01 16.3 0.0 0.03 14.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG19911.1 - 0.078 13.0 0.1 11 6.3 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG19911.1 - 0.12 12.6 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 HOASN PF14515.6 EGG19911.1 - 0.15 12.4 0.1 0.41 11.1 0.1 1.7 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices PBD PF00786.28 EGG19911.1 - 0.21 12.0 0.7 1 9.8 0.7 2.1 1 0 0 1 1 1 0 P21-Rho-binding domain RNA_helicase PF00910.22 EGG19912.1 - 0.032 14.6 0.1 0.12 12.8 0.1 2.0 1 0 0 1 1 1 0 RNA helicase Hep_59 PF07052.11 EGG19914.1 - 0.012 16.4 0.9 0.019 15.7 0.9 1.3 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 SR-25 PF10500.9 EGG19914.1 - 0.69 9.5 4.7 1.1 8.9 4.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 EGG19914.1 - 0.78 10.3 2.9 1.2 9.7 2.9 1.2 1 0 0 1 1 1 0 Dehydrin UPF0240 PF06784.11 EGG19915.1 - 0.1 12.7 0.1 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) Mito_fiss_reg PF05308.11 EGG19915.1 - 0.65 10.0 5.9 1.2 9.2 5.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DC_STAMP PF07782.13 EGG19916.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 DC-STAMP-like protein Pkinase PF00069.25 EGG19917.1 - 3.3e-59 200.4 0.0 7.8e-59 199.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG19917.1 - 1.9e-53 181.4 0.0 4.3e-53 180.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGG19917.1 - 0.0049 16.2 0.1 0.0079 15.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGG19917.1 - 0.0095 14.8 4.2 0.01 14.7 0.0 2.5 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGG19917.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pyridoxal_deC PF00282.19 EGG19918.1 - 4.7e-11 42.0 0.0 1.1e-05 24.4 0.0 2.1 1 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain RasGAP PF00616.19 EGG19919.1 - 3.3e-36 125.0 0.8 3.3e-36 125.0 0.8 5.1 3 2 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 EGG19919.1 - 8e-33 112.9 1.3 4.4e-16 59.0 0.0 3.6 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGG19919.1 - 0.016 15.1 0.1 0.064 13.1 0.1 2.1 1 0 0 1 1 1 0 CAMSAP CH domain Cyto_heme_lyase PF01265.17 EGG19920.1 - 3e-59 201.0 10.0 1.6e-58 198.6 10.0 1.8 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase tRNA_bind PF01588.20 EGG19921.1 - 5e-19 68.2 0.0 4.1e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 Putative tRNA binding domain OsmC PF02566.19 EGG19922.1 - 4e-14 52.9 0.2 6e-14 52.3 0.2 1.3 1 0 0 1 1 1 1 OsmC-like protein Peptidase_M74 PF03411.13 EGG19925.1 - 0.1 12.1 2.2 5 6.6 0.4 2.0 1 1 1 2 2 2 0 Penicillin-insensitive murein endopeptidase GATA PF00320.27 EGG19926.1 - 4.5e-13 48.6 6.9 9.2e-13 47.6 6.9 1.5 1 0 0 1 1 1 1 GATA zinc finger Sen15 PF09631.10 EGG19927.1 - 6.6e-14 52.0 2.4 2.4e-07 31.0 0.3 2.6 2 1 0 2 2 2 2 Sen15 protein FtsH_ext PF06480.15 EGG19927.1 - 2.5 8.5 9.1 0.16 12.3 3.1 2.1 2 2 0 2 2 2 0 FtsH Extracellular Glyco_hydro_31 PF01055.26 EGG19928.1 - 6.4e-142 473.8 7.6 8.4e-142 473.4 7.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGG19928.1 - 3.5e-23 81.7 0.6 2.4e-22 79.0 0.0 2.9 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 EGG19928.1 - 1e-08 35.3 0.3 3.2e-08 33.7 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Ank_4 PF13637.6 EGG19929.1 - 5.7e-20 71.4 1.2 5.4e-10 39.6 0.0 3.1 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG19929.1 - 3.8e-19 69.1 5.8 1e-10 42.0 1.1 3.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG19929.1 - 1.6e-16 60.1 1.9 3.2e-10 40.0 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGG19929.1 - 6.8e-15 54.8 9.4 2.3e-05 24.6 0.4 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EGG19929.1 - 1e-10 40.8 1.4 0.044 14.3 0.0 4.8 3 1 0 3 3 3 3 Ankyrin repeat F-box PF00646.33 EGG19929.1 - 0.031 14.2 0.1 0.1 12.5 0.1 2.0 1 0 0 1 1 1 0 F-box domain DNA_pol3_beta_2 PF02767.16 EGG19929.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain Pro_isomerase PF00160.21 EGG19930.1 - 1.4e-47 161.9 0.1 1.4e-47 161.9 0.1 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 EGG19930.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Mucin PF01456.17 EGG19930.1 - 0.77 9.8 8.3 1.4 8.9 8.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.9 EGG19930.1 - 8.3 4.8 35.1 1.4 7.4 13.0 2.1 2 0 0 2 2 2 0 Macoilin family Lysine_decarbox PF03641.14 EGG19932.1 - 1.1e-27 96.7 0.0 2.6e-27 95.5 0.0 1.6 1 1 1 2 2 2 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EGG19932.1 - 3.4e-13 49.5 0.0 3.8e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 SLOG cluster4 family ubiquitin PF00240.23 EGG19933.1 - 7.7e-08 32.0 0.1 1.5e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 EGG19933.1 - 0.00031 20.8 0.0 0.00086 19.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGG19933.1 - 0.006 17.1 0.4 0.006 17.1 0.4 2.9 3 1 0 3 3 3 1 DUF2407 ubiquitin-like domain OAD_gamma PF04277.13 EGG19933.1 - 0.11 13.1 0.4 15 6.3 0.0 3.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Rad60-SLD PF11976.8 EGG19933.1 - 0.33 10.8 3.3 0.37 10.7 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Orf78 PF06024.12 EGG19933.1 - 3.4 8.0 0.0 3.4 8.0 0.0 5.6 6 0 0 6 6 6 0 Orf78 (ac78) FNIP PF05725.12 EGG19937.1 - 0.0031 17.6 4.7 4.8 7.4 0.0 5.5 6 0 0 6 6 6 2 FNIP Repeat LRR_8 PF13855.6 EGG19937.1 - 0.054 13.3 2.9 4.3 7.2 1.5 3.8 3 0 0 3 3 3 0 Leucine rich repeat Torus PF16131.5 EGG19938.1 - 9.3e-29 100.3 0.5 9.3e-29 100.3 0.5 3.1 2 1 0 2 2 2 1 Torus domain RRM_1 PF00076.22 EGG19938.1 - 3.5e-06 26.8 0.0 7.2e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EGG19938.1 - 0.00083 19.3 1.0 0.0015 18.5 1.0 1.5 1 0 0 1 1 1 1 Zinc finger domain FSA_C PF10479.9 EGG19938.1 - 0.4 8.8 7.4 0.55 8.3 7.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus zf-CCCH_4 PF18044.1 EGG19938.1 - 0.65 9.9 3.2 1.1 9.1 3.2 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger SieB PF14163.6 EGG19938.1 - 0.65 9.5 7.3 0.66 9.5 1.1 2.6 2 1 0 2 2 2 0 Super-infection exclusion protein B MID_MedPIWI PF18296.1 EGG19938.1 - 5 6.8 20.3 12 5.6 20.3 1.6 1 0 0 1 1 1 0 MID domain of medPIWI LRR_6 PF13516.6 EGG19939.1 - 0.00064 19.6 10.8 12 6.3 0.0 7.8 8 0 0 8 8 8 3 Leucine Rich repeat G-alpha PF00503.20 EGG19940.1 - 1.3e-91 307.4 6.4 1.7e-91 307.1 6.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGG19940.1 - 5.7e-14 51.9 0.2 5.1e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGG19940.1 - 0.00017 21.8 1.0 0.61 10.3 0.0 3.0 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGG19940.1 - 0.00043 19.7 0.5 0.1 11.9 0.1 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG19940.1 - 0.017 15.2 1.1 3 7.9 0.0 2.7 3 1 0 3 3 3 0 50S ribosome-binding GTPase Tubulin PF00091.25 EGG19941.1 - 6.6e-46 157.0 0.2 3.3e-45 154.7 0.0 2.1 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGG19941.1 - 2.5e-08 34.1 0.2 8.1e-08 32.5 0.2 1.9 2 1 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGG19941.1 - 0.019 15.3 0.3 0.077 13.3 0.0 2.3 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain CLU PF13236.6 EGG19942.1 - 6.4e-50 170.0 0.0 1.3e-49 169.1 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria Ras PF00071.22 EGG19942.1 - 7.2e-33 113.5 0.1 1.6e-31 109.1 0.1 2.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG19942.1 - 5.9e-17 62.0 0.2 5.9e-17 62.0 0.2 3.0 2 1 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG19942.1 - 2.3e-09 37.0 0.0 5.9e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family eIF3_p135 PF12807.7 EGG19942.1 - 0.00023 21.2 0.1 0.00023 21.2 0.1 2.9 3 0 0 3 3 2 1 Translation initiation factor eIF3 subunit 135 TPR_2 PF07719.17 EGG19942.1 - 0.0011 18.9 2.2 0.031 14.4 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG19942.1 - 0.0048 17.4 0.2 0.073 13.6 0.0 3.0 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG19942.1 - 0.0065 16.6 0.3 0.036 14.3 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG19942.1 - 0.0078 16.0 0.0 0.044 13.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Rsd_AlgQ PF04353.13 EGG19942.1 - 0.043 13.8 0.3 0.13 12.2 0.3 1.8 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TPR_17 PF13431.6 EGG19942.1 - 0.057 13.8 6.4 6 7.5 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGG19942.1 - 0.12 13.0 0.0 0.12 13.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG19942.1 - 0.15 13.0 0.1 1.1 10.2 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat AAA_22 PF13401.6 EGG19942.1 - 0.27 11.5 1.1 0.72 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain PTPLA PF04387.14 EGG19943.1 - 3.7e-47 160.1 14.0 3.7e-47 160.1 14.0 1.6 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA SMN PF06003.12 EGG19944.1 - 2.3e-06 27.1 1.0 2.9e-06 26.7 0.2 1.6 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 EGG19944.1 - 8.6e-06 25.8 0.0 2.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 EGG19944.1 - 0.0023 18.4 0.0 0.0064 16.9 0.0 1.7 1 0 0 1 1 1 1 Agenet domain RMI2 PF16100.5 EGG19944.1 - 0.053 13.3 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 zf-RING_9 PF13901.6 EGG19945.1 - 8.4e-59 199.0 10.0 8.4e-59 199.0 10.0 2.5 3 0 0 3 3 3 1 Putative zinc-RING and/or ribbon RUN PF02759.19 EGG19945.1 - 4.1e-15 55.9 1.0 4.1e-15 55.9 1.0 3.1 4 0 0 4 4 4 1 RUN domain CLU PF13236.6 EGG19946.1 - 9.8e-53 179.2 0.0 1.7e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGG19946.1 - 4.8e-06 26.7 0.1 1.5e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EGG19946.1 - 0.0094 16.2 0.1 0.035 14.4 0.1 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG19946.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGG19946.1 - 0.12 12.2 0.2 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.6 EGG19946.1 - 1.7 8.4 13.2 2.3 8.1 5.9 3.6 2 1 1 3 3 3 0 Leucine rich repeat Cofilin_ADF PF00241.20 EGG19947.1 - 7e-37 125.9 0.1 9.4e-37 125.5 0.1 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RRM_1 PF00076.22 EGG19948.1 - 1.2e-15 57.1 0.9 2.9e-08 33.4 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGG19948.1 - 0.47 10.5 0.0 0.47 10.5 0.0 4.1 5 0 0 5 5 5 0 RNA binding motif ANTH PF07651.16 EGG19949.1 - 3.4e-46 157.5 0.7 5e-46 156.9 0.7 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 EGG19949.1 - 1.9e-05 24.7 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 ENTH domain PPR_long PF17177.4 EGG19950.1 - 0.049 13.0 0.7 11 5.3 0.0 3.1 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EGG19950.1 - 0.071 13.2 1.5 0.54 10.4 1.2 2.7 3 0 0 3 3 3 0 Pentatricopeptide repeat domain DnaT PF17948.1 EGG19950.1 - 0.094 12.4 0.4 0.29 10.8 0.4 1.8 1 0 0 1 1 1 0 DnaT DNA-binding domain DUF2400 PF09674.10 EGG19950.1 - 0.18 11.8 2.5 0.38 10.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) PPR_2 PF13041.6 EGG19950.1 - 0.32 11.2 3.3 2.4 8.4 0.0 3.7 4 1 1 5 5 5 0 PPR repeat family Dna2 PF08696.11 EGG19950.1 - 0.48 10.2 5.8 6.5 6.5 0.1 2.6 2 0 0 2 2 2 0 DNA replication factor Dna2 SDA1 PF05285.12 EGG19951.1 - 5.5e-05 22.7 26.4 6.9e-05 22.4 26.4 1.1 1 0 0 1 1 1 1 SDA1 Cwf_Cwc_15 PF04889.12 EGG19951.1 - 0.0039 16.9 25.1 0.0067 16.2 25.1 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 EGG19951.1 - 0.0043 16.4 32.3 0.0056 16.1 32.3 1.1 1 0 0 1 1 1 1 BUD22 SAP PF02037.27 EGG19951.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 SAP domain Nop14 PF04147.12 EGG19951.1 - 0.02 13.1 32.2 0.028 12.7 32.2 1.1 1 0 0 1 1 1 0 Nop14-like family Calici_coat_C PF08435.11 EGG19951.1 - 0.023 14.2 2.0 0.035 13.6 2.0 1.3 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal DUF913 PF06025.12 EGG19951.1 - 0.061 12.3 6.5 0.092 11.7 6.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spore_coat_CotO PF14153.6 EGG19951.1 - 0.09 12.7 25.1 0.14 12.1 25.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.17 EGG19951.1 - 0.11 11.2 11.7 0.14 10.9 11.7 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EGG19951.1 - 0.18 9.9 13.3 0.21 9.7 13.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mitofilin PF09731.9 EGG19951.1 - 0.19 10.6 23.2 0.25 10.1 23.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SAPS PF04499.15 EGG19951.1 - 0.66 8.7 15.1 0.81 8.4 15.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4045 PF13254.6 EGG19951.1 - 1.5 8.4 13.6 1.9 8.1 13.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Zip PF02535.22 EGG19951.1 - 2.3 7.3 10.7 2.9 7.0 10.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 EGG19951.1 - 4 6.8 21.3 2.5e+02 0.9 21.3 2.1 1 1 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CDC27 PF09507.10 EGG19951.1 - 4.9 6.4 31.6 6.9 5.9 31.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDRGK PF09756.9 EGG19951.1 - 7.6 6.1 37.9 13 5.3 37.9 1.4 1 0 0 1 1 1 0 DDRGK domain DNA_pol_phi PF04931.13 EGG19952.1 - 0.0072 14.5 8.3 0.0074 14.5 8.3 1.1 1 0 0 1 1 1 1 DNA polymerase phi RXT2_N PF08595.11 EGG19952.1 - 0.013 15.6 3.7 0.021 14.9 3.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 EGG19952.1 - 0.018 14.7 2.8 0.024 14.3 2.8 1.2 1 0 0 1 1 1 0 FAM176 family DUF4746 PF15928.5 EGG19952.1 - 0.041 13.3 3.6 0.05 13.0 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Sporozoite_P67 PF05642.11 EGG19952.1 - 0.053 11.6 5.7 0.063 11.4 5.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GOLD_2 PF13897.6 EGG19952.1 - 0.24 11.9 2.6 0.36 11.3 2.6 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Ank_2 PF12796.7 EGG19953.1 - 2.9e-34 117.5 6.8 2.7e-06 27.9 0.1 7.0 3 3 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG19953.1 - 9.8e-29 99.0 11.8 0.00015 22.0 0.0 12.4 7 2 7 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19953.1 - 3.3e-22 76.2 7.8 3.6 8.5 0.0 13.7 13 1 1 14 14 14 5 Ankyrin repeat Ank_4 PF13637.6 EGG19953.1 - 1.2e-21 76.7 7.8 0.0013 19.3 0.0 9.3 3 3 9 12 12 12 7 Ankyrin repeats (many copies) Ank PF00023.30 EGG19953.1 - 0.0006 20.1 1.4 36 5.1 0.0 7.4 9 1 0 9 9 9 0 Ankyrin repeat DUF3447 PF11929.8 EGG19953.1 - 0.0011 18.9 26.3 0.18 11.8 1.2 7.2 4 2 3 8 8 8 2 Domain of unknown function (DUF3447) DUF5049 PF16468.5 EGG19953.1 - 0.055 13.4 0.0 54 3.8 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF5049) Myb_DNA-binding PF00249.31 EGG19954.1 - 6.8e-56 186.2 36.2 1.3e-15 57.3 0.6 5.8 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG19954.1 - 2.2e-48 162.3 19.1 1.2e-12 47.9 0.3 6.3 1 1 4 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 EGG19954.1 - 3e-09 36.9 17.5 0.022 14.8 0.0 6.5 6 1 1 7 7 7 4 SLIDE Rap1_C PF11626.8 EGG19954.1 - 0.0029 17.7 8.2 2.9 8.1 0.2 4.5 2 1 1 3 3 3 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain Cas_Csy4 PF09618.10 EGG19954.1 - 3.3 7.8 8.0 12 6.0 3.7 2.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) Myb_DNA-bind_5 PF13873.6 EGG19954.1 - 4.3 7.5 17.1 9.3 6.4 0.4 6.1 5 1 0 5 5 5 0 Myb/SANT-like DNA-binding domain Steroid_dh PF02544.16 EGG19955.1 - 9.6e-28 97.1 7.6 9.6e-28 97.1 7.6 2.2 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EGG19955.1 - 0.0052 17.2 0.3 0.0052 17.2 0.3 2.5 3 0 0 3 3 3 1 Phospholipid methyltransferase PrgI PF12666.7 EGG19955.1 - 0.28 11.9 11.1 7 7.4 0.3 3.4 3 0 0 3 3 3 0 PrgI family protein UDPGP PF01704.18 EGG19956.1 - 1.1e-187 623.8 1.5 1.4e-187 623.5 1.5 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase LRR_6 PF13516.6 EGG19957.1 - 8.8e-18 62.8 32.6 0.00033 20.5 1.5 8.8 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 EGG19957.1 - 1.3e-07 31.2 8.0 16 6.5 0.0 7.7 7 0 0 7 7 7 1 Leucine Rich Repeat Carm_PH PF17888.1 EGG19957.1 - 0.0004 20.7 0.1 0.0018 18.6 0.0 2.1 2 0 0 2 2 2 1 Carmil pleckstrin homology domain FTH PF01827.27 EGG19957.1 - 0.0086 15.9 0.4 0.33 10.7 0.0 2.6 2 0 0 2 2 2 1 FTH domain LRR_4 PF12799.7 EGG19957.1 - 0.011 16.1 23.5 0.16 12.5 2.3 6.5 4 2 3 7 7 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG19957.1 - 0.099 12.4 17.9 1.1 9.1 0.9 5.5 6 1 1 7 7 7 0 Leucine rich repeat Peroxin-13_N PF04088.13 EGG19960.1 - 8.2e-24 84.5 1.8 8.2e-24 84.5 1.8 3.3 4 1 0 4 4 4 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 EGG19960.1 - 2.6e-14 52.5 0.0 5.1e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG19960.1 - 1.1e-12 47.4 0.1 2.8e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGG19960.1 - 1.3e-11 44.2 0.1 2.7e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain FlaF PF07309.11 EGG19960.1 - 0.047 13.7 0.3 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF Prok-RING_4 PF14447.6 EGG19960.1 - 1.6 8.7 4.0 5.4 7.0 3.9 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 CTK3 PF12243.8 EGG19961.1 - 5.8e-12 45.7 0.9 5.8e-12 45.7 0.9 2.6 3 0 0 3 3 3 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 EGG19961.1 - 0.0002 22.1 4.9 0.00042 21.1 0.2 3.4 3 0 0 3 3 3 1 RNA polymerase II-binding domain. zf-CCCH_6 PF18585.1 EGG19961.1 - 0.42 10.5 1.3 2.5 8.0 0.0 2.9 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Ribosomal_L7Ae PF01248.26 EGG19962.1 - 5.6e-27 93.3 0.1 7.4e-27 92.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EGG19962.1 - 0.0022 18.1 0.2 0.0025 17.9 0.2 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EGG19962.1 - 0.0088 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain WD40 PF00400.32 EGG19964.1 - 5e-17 62.0 4.3 0.45 11.5 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG19964.1 - 2.7e-10 40.4 0.0 3.7e-05 23.9 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG19964.1 - 5.8e-07 29.1 3.7 5.8e-06 25.9 1.9 2.3 1 1 1 2 2 2 1 WD40-like domain PQQ_3 PF13570.6 EGG19964.1 - 3.9e-05 24.0 0.2 4.7 7.8 0.0 4.1 5 0 0 5 5 5 1 PQQ-like domain Ge1_WD40 PF16529.5 EGG19964.1 - 0.0027 16.7 0.2 2.2 7.2 0.0 3.9 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGG19964.1 - 0.0086 16.0 0.0 0.46 10.3 0.0 2.7 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 EGG19964.1 - 0.024 14.5 0.5 3.3 7.8 0.1 2.8 3 0 0 3 3 3 0 PQQ enzyme repeat SDA1 PF05285.12 EGG19964.1 - 0.12 11.8 45.0 0.19 11.2 45.0 1.3 1 0 0 1 1 1 0 SDA1 Peptidase_S30 PF01577.16 EGG19964.1 - 0.56 9.8 7.4 0.92 9.1 7.4 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease BUD22 PF09073.10 EGG19964.1 - 6.4 6.0 44.9 9.9 5.4 44.9 1.2 1 0 0 1 1 1 0 BUD22 AAA_25 PF13481.6 EGG19965.1 - 4e-07 29.8 0.0 1.2e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.11 EGG19965.1 - 0.0011 18.3 0.0 0.022 14.0 0.0 2.3 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 EGG19965.1 - 0.022 14.1 1.0 0.94 8.8 0.0 2.5 1 1 0 2 2 2 0 KaiC AAA_24 PF13479.6 EGG19965.1 - 0.062 13.0 3.7 0.2 11.3 2.1 2.6 2 1 0 2 2 2 0 AAA domain DUF2615 PF11027.8 EGG19965.1 - 1.3 9.2 5.0 1.3 9.2 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Secretin_N_2 PF07655.13 EGG19965.1 - 1.6 9.4 13.9 18 6.0 9.8 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain MAPEG PF01124.18 EGG19966.1 - 0.00093 19.1 0.2 0.0012 18.8 0.2 1.2 1 0 0 1 1 1 1 MAPEG family DUF4834 PF16118.5 EGG19967.1 - 0.0003 21.7 1.4 0.0003 21.7 1.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) Shisa PF13908.6 EGG19967.1 - 0.0039 17.5 3.3 0.0039 17.5 3.3 2.8 3 0 0 3 3 3 1 Wnt and FGF inhibitory regulator SARAF PF06682.12 EGG19967.1 - 0.0043 16.8 0.6 0.0087 15.7 0.6 1.4 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF3139 PF11337.8 EGG19967.1 - 0.013 16.2 4.3 2 9.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) SCIMP PF15050.6 EGG19967.1 - 0.035 14.6 0.2 0.28 11.6 0.2 2.4 2 0 0 2 2 2 0 SCIMP protein Ctr PF04145.15 EGG19967.1 - 0.19 12.4 0.5 0.68 10.6 0.3 1.9 2 0 0 2 2 2 0 Ctr copper transporter family DUF4446 PF14584.6 EGG19967.1 - 0.2 11.7 1.2 0.47 10.4 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF5359 PF17313.2 EGG19967.1 - 0.99 9.4 3.2 2.7 8.0 3.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5359) EphA2_TM PF14575.6 EGG19967.1 - 1.1 10.2 8.0 9.1 7.2 4.9 2.7 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain WD40 PF00400.32 EGG19968.1 - 2.2e-34 116.9 7.2 8.2e-09 36.0 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG19968.1 - 1.4e-13 51.0 0.1 0.00018 21.7 0.0 5.4 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG19968.1 - 0.0077 15.2 0.1 0.61 9.0 0.0 3.6 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EGG19968.1 - 0.019 14.3 0.4 0.33 10.2 0.1 2.4 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal FlaC_arch PF05377.11 EGG19968.1 - 0.032 14.6 0.0 0.09 13.2 0.0 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 EGG19968.1 - 0.032 14.3 0.3 0.066 13.3 0.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor Macoilin PF09726.9 EGG19968.1 - 0.085 11.4 5.8 0.12 10.9 5.8 1.2 1 0 0 1 1 1 0 Macoilin family Tmemb_cc2 PF10267.9 EGG19968.1 - 0.19 10.9 6.0 0.27 10.3 6.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF812 PF05667.11 EGG19968.1 - 0.21 10.4 3.2 0.27 10.0 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ATG16 PF08614.11 EGG19968.1 - 0.22 11.7 4.7 0.36 11.0 4.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Prominin PF05478.11 EGG19968.1 - 0.57 8.1 3.4 0.94 7.3 3.4 1.2 1 0 0 1 1 1 0 Prominin Fib_alpha PF08702.10 EGG19968.1 - 0.71 10.1 3.9 1.7 8.8 3.9 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FPP PF05911.11 EGG19968.1 - 2.9 6.0 6.2 0.75 7.9 3.0 1.5 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil HNF-1_N PF04814.13 EGG19968.1 - 7.4 7.1 11.7 2.2 8.8 8.2 1.9 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus NAD_binding_10 PF13460.6 EGG19969.1 - 5.6e-09 36.1 0.0 9.1e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGG19969.1 - 4.6e-07 29.6 0.0 7.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EGG19969.1 - 4e-06 26.5 0.0 0.00063 19.3 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG19969.1 - 4.2e-06 26.0 0.1 4.3e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGG19969.1 - 0.00017 20.8 0.0 0.00026 20.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGG19969.1 - 0.0016 17.6 0.1 0.003 16.8 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 EGG19969.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.20 EGG19969.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 EGG19969.1 - 0.074 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EGG19969.1 - 0.084 12.2 0.1 0.34 10.3 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase WD40 PF00400.32 EGG19970.1 - 6.8e-16 58.4 6.4 1.7e-05 25.5 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG19970.1 - 1.9e-11 44.1 0.0 0.0097 16.2 0.0 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DUF3439 PF11921.8 EGG19970.1 - 0.012 15.6 10.9 0.035 14.1 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) WD40_like PF17005.5 EGG19970.1 - 0.02 14.2 5.2 1 8.6 0.0 3.7 4 0 0 4 4 4 0 WD40-like domain SNF2_N PF00176.23 EGG19971.1 - 9.1e-37 126.6 0.0 2.5e-36 125.2 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Ribosomal_S21e PF01249.18 EGG19971.1 - 4.4e-36 122.8 0.0 1e-35 121.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S21e Helicase_C PF00271.31 EGG19971.1 - 3.9e-11 43.3 0.0 2.2e-10 40.9 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGG19971.1 - 0.37 11.1 5.1 0.84 9.9 0.0 3.9 5 1 0 5 5 5 0 AAA domain Pyr_redox_2 PF07992.14 EGG19972.1 - 4.3e-09 36.0 0.0 4.8e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF3164 PF11363.8 EGG19972.1 - 0.015 14.9 0.4 0.02 14.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3164) Exog_C PF18026.1 EGG19972.1 - 0.017 15.2 0.2 0.031 14.3 0.2 1.4 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain DUF604 PF04646.12 EGG19972.1 - 0.038 13.4 0.2 0.062 12.7 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF604 DUF1890 PF09001.11 EGG19972.1 - 0.038 14.4 0.4 0.043 14.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) Pyr_redox PF00070.27 EGG19972.1 - 0.055 14.0 0.1 0.093 13.3 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGG19972.1 - 0.17 11.4 0.8 0.33 10.5 0.6 1.6 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG19973.1 - 3.4e-12 46.2 0.0 5.6e-11 42.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 EGG19973.1 - 7.8e-07 28.9 0.9 0.00011 22.0 0.0 2.8 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 EGG19973.1 - 0.00069 19.0 0.3 0.0017 17.7 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGG19973.1 - 0.048 13.0 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Ank_2 PF12796.7 EGG19974.1 - 5e-31 107.1 2.4 2e-06 28.3 0.1 7.2 5 2 2 7 7 7 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG19974.1 - 1.9e-24 85.4 9.2 0.0025 18.1 0.0 13.0 8 3 6 14 14 14 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG19974.1 - 2.4e-22 79.0 8.6 0.00038 20.9 0.1 10.6 8 4 2 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19974.1 - 5.5e-19 66.3 7.4 6.3 7.7 0.0 13.5 14 0 0 14 14 14 4 Ankyrin repeat DUF3447 PF11929.8 EGG19974.1 - 1.3e-05 25.0 21.1 0.072 13.1 0.5 7.3 5 2 2 7 7 7 3 Domain of unknown function (DUF3447) Rieske PF00355.26 EGG19974.1 - 0.0097 15.8 0.0 6.4 6.8 0.0 2.4 2 0 0 2 2 2 2 Rieske [2Fe-2S] domain Ank PF00023.30 EGG19974.1 - 0.11 13.0 4.9 2e+02 2.7 0.0 7.4 8 1 1 9 9 9 0 Ankyrin repeat Ank_2 PF12796.7 EGG19975.1 - 2.3e-29 101.8 14.0 1.5e-06 28.7 0.1 5.8 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG19975.1 - 7.1e-28 96.3 4.8 0.00015 22.0 0.1 10.7 3 2 8 11 11 11 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG19975.1 - 8.5e-24 83.6 2.8 5e-05 23.8 0.0 8.4 4 3 5 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG19975.1 - 2.8e-21 73.3 1.3 2.6 8.9 0.0 12.2 13 0 0 13 13 13 4 Ankyrin repeat DUF3447 PF11929.8 EGG19975.1 - 2.4e-07 30.6 12.0 0.1 12.6 1.2 5.3 3 2 1 4 4 4 3 Domain of unknown function (DUF3447) Ank PF00023.30 EGG19975.1 - 0.00086 19.6 1.3 34 5.1 0.0 7.3 8 1 0 8 8 8 0 Ankyrin repeat RNase_P_p30 PF01876.16 EGG19975.1 - 0.019 14.4 0.1 0.89 9.0 0.0 2.6 2 1 0 2 2 2 0 RNase P subunit p30 BTHB PF18410.1 EGG19975.1 - 0.05 13.4 2.0 1.4 8.8 0.0 4.2 6 0 0 6 6 6 0 Basic tilted helix bundle domain PPE PF00823.19 EGG19975.1 - 0.4 10.8 1.4 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 PPE family DSPc PF00782.20 EGG19976.1 - 7.1e-32 110.0 0.1 1.4e-31 109.1 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG19976.1 - 0.00015 21.4 0.0 0.00034 20.3 0.0 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGG19976.1 - 0.0011 18.9 0.2 0.003 17.6 0.1 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family RAG1_imp_bd PF12560.8 EGG19976.1 - 0.026 14.1 0.1 0.05 13.1 0.1 1.4 1 0 0 1 1 1 0 RAG1 importin binding Rod_C PF10493.9 EGG19976.1 - 0.063 11.7 0.3 0.095 11.1 0.3 1.2 1 0 0 1 1 1 0 Rough deal protein C-terminal region TSNAXIP1_N PF15739.5 EGG19976.1 - 0.56 10.6 4.9 12 6.3 0.0 2.3 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus zf-AN1 PF01428.16 EGG19976.1 - 4.2 7.6 7.4 1.6 9.0 1.0 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger WD40 PF00400.32 EGG19977.1 - 5e-25 87.3 19.3 9.3e-06 26.3 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat F-box-like PF12937.7 EGG19977.1 - 2.8e-06 27.1 0.0 6.2e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like BBS2_Mid PF14783.6 EGG19977.1 - 0.00014 21.9 0.1 1.5 8.9 0.0 4.1 4 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 EGG19977.1 - 0.00073 18.3 15.8 0.0072 15.0 1.1 4.9 3 1 2 5 5 5 3 Nucleoporin Nup120/160 F-box PF00646.33 EGG19977.1 - 0.0012 18.7 1.8 0.51 10.3 0.2 2.7 2 0 0 2 2 2 2 F-box domain F-box-like_2 PF13013.6 EGG19977.1 - 0.026 14.5 0.1 0.07 13.1 0.1 1.7 1 1 0 1 1 1 0 F-box-like domain RasGEF PF00617.19 EGG19978.1 - 4.1e-44 150.9 0.3 1.6e-43 148.9 0.3 2.1 1 0 0 1 1 1 1 RasGEF domain GRAM PF02893.20 EGG19978.1 - 5.5e-13 48.8 4.3 1e-12 48.0 2.3 2.4 2 0 0 2 2 2 1 GRAM domain RhoGAP PF00620.27 EGG19978.1 - 9.8e-07 28.7 1.8 4e-06 26.7 1.8 2.2 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.20 EGG19978.1 - 0.0039 17.4 0.6 0.0039 17.4 0.6 6.1 6 2 0 6 6 6 1 RasGEF N-terminal motif Methyltransf_25 PF13649.6 EGG19979.1 - 1.6e-07 31.9 0.0 3.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG19979.1 - 0.00062 20.4 0.0 0.0014 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG19979.1 - 0.00096 19.0 0.0 0.0025 17.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Macoilin PF09726.9 EGG19979.1 - 0.038 12.6 12.3 0.047 12.3 12.3 1.1 1 0 0 1 1 1 0 Macoilin family Mucin PF01456.17 EGG19979.1 - 0.066 13.2 15.3 0.11 12.5 15.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Methyltransf_12 PF08242.12 EGG19979.1 - 0.18 12.6 2.6 1.6 9.5 0.0 3.2 3 1 0 3 3 3 0 Methyltransferase domain Peptidase_S64 PF08192.11 EGG19979.1 - 0.34 9.4 14.6 0.43 9.0 14.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Methyltransf_31 PF13847.6 EGG19979.1 - 0.51 10.1 2.6 0.99 9.2 0.1 2.4 2 1 0 2 2 2 0 Methyltransferase domain zf-UBR PF02207.20 EGG19980.1 - 6.3e-12 45.5 10.0 6.3e-12 45.5 10.0 3.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-C3HC4_2 PF13923.6 EGG19980.1 - 0.00023 20.9 2.1 0.00023 20.9 2.1 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SUB1_ProdP9 PF18213.1 EGG19980.1 - 0.058 13.3 1.5 0.25 11.2 0.1 2.9 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 Cation_ATPase_C PF00689.21 EGG19981.1 - 6.6e-40 136.8 7.7 6.6e-40 136.8 7.7 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGG19981.1 - 2.4e-32 111.9 6.4 2.4e-32 111.9 6.4 3.4 3 1 1 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGG19981.1 - 3.7e-18 65.4 0.0 1e-17 64.0 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGG19981.1 - 7.4e-15 55.8 0.0 4.8e-14 53.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGG19981.1 - 3.6e-13 49.0 0.0 1.4e-12 47.1 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Wzy_C PF04932.15 EGG19981.1 - 0.013 15.1 2.0 0.27 10.9 0.2 3.1 3 0 0 3 3 3 0 O-Antigen ligase JTB PF05439.12 EGG19981.1 - 0.42 10.7 4.1 0.53 10.3 0.8 2.8 2 0 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) Phage_holin_3_6 PF07332.11 EGG19981.1 - 0.62 10.1 9.1 0.29 11.2 0.6 3.0 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III TrbC PF04956.13 EGG19981.1 - 2.9 8.2 14.3 2 8.7 0.5 4.5 4 1 1 5 5 4 0 TrbC/VIRB2 family DUF1514 PF07438.11 EGG19981.1 - 3.1 7.7 8.0 1.9 8.4 1.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1514) Vfa1 PF08432.10 EGG19981.1 - 7.2 6.9 33.9 2.5 8.4 16.0 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PAT1 PF09770.9 EGG19982.1 - 1.1e-05 24.0 2.3 1.1e-05 24.0 2.3 4.2 2 2 1 3 3 3 1 Topoisomerase II-associated protein PAT1 Synaptobrevin PF00957.21 EGG19983.1 - 2.1e-12 46.7 2.1 3.7e-12 45.9 2.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGG19983.1 - 0.0024 17.9 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain T3SS_ATPase_C PF18269.1 EGG19983.1 - 0.058 13.3 0.7 0.15 11.9 0.2 2.1 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain SE PF08491.10 EGG19984.1 - 3.3e-87 292.0 0.0 4.7e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EGG19984.1 - 7.2e-20 71.5 0.0 9e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGG19984.1 - 7.6e-10 38.9 0.1 4.3e-05 23.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 EGG19984.1 - 3.6e-07 29.6 0.5 7e-07 28.7 0.5 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 EGG19984.1 - 3.3e-05 23.2 0.6 0.00055 19.2 0.2 2.2 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 EGG19984.1 - 0.00015 20.8 2.1 0.095 11.5 0.0 2.5 2 1 1 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.24 EGG19984.1 - 0.00031 20.0 1.6 0.0032 16.6 0.8 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EGG19984.1 - 0.00069 20.1 2.4 0.0035 17.9 0.4 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGG19984.1 - 0.00094 18.5 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG19984.1 - 0.0043 17.2 0.3 0.0094 16.2 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 EGG19984.1 - 0.0044 17.1 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 EGG19984.1 - 0.0057 16.8 0.2 0.025 14.7 0.2 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 EGG19984.1 - 0.0085 16.3 0.4 0.02 15.2 0.1 1.7 2 0 0 2 2 1 1 TrkA-N domain 3HCDH_N PF02737.18 EGG19984.1 - 0.009 15.9 0.4 0.021 14.7 0.4 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EGG19984.1 - 0.013 14.9 2.3 0.035 13.5 2.3 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGG19984.1 - 0.026 13.8 0.3 0.042 13.1 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGG19984.1 - 0.027 13.2 0.2 0.043 12.5 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 EGG19984.1 - 0.027 14.1 0.1 0.067 12.8 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EGG19984.1 - 0.034 14.6 0.0 0.16 12.4 0.0 2.1 3 0 0 3 3 2 0 Putative NAD(P)-binding F420_oxidored PF03807.17 EGG19984.1 - 0.098 13.2 0.1 0.33 11.6 0.1 2.0 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 EGG19984.1 - 0.1 12.2 0.2 0.21 11.1 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EGG19984.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 EGG19984.1 - 0.11 11.7 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EGG19984.1 - 0.12 11.4 0.6 0.41 9.6 0.3 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 EGG19984.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Med13_C PF06333.12 EGG19985.1 - 0.13 11.5 3.5 0.2 10.9 3.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DUF3539 PF12058.8 EGG19985.1 - 0.63 10.2 3.4 0.47 10.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3539) CCSAP PF15748.5 EGG19985.1 - 1.6 8.8 9.9 2.6 8.1 9.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated BUD22 PF09073.10 EGG19985.1 - 1.8 7.8 17.7 2.4 7.4 17.7 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EGG19985.1 - 1.8 7.9 21.3 2.4 7.5 21.3 1.1 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.10 EGG19985.1 - 2.8 8.2 16.3 5.4 7.3 16.3 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RPN2_C PF18004.1 EGG19985.1 - 6.1 6.7 17.0 12 5.7 17.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 EGG19985.1 - 9.4 4.4 22.7 14 3.8 22.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 EGG19985.1 - 9.9 5.9 11.4 23 4.7 11.4 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RTA1 PF04479.13 EGG19987.1 - 9.5e-52 175.6 7.1 1.4e-51 175.1 7.1 1.2 1 0 0 1 1 1 1 RTA1 like protein UPF0542 PF15086.6 EGG19987.1 - 0.32 11.0 2.3 3.6 7.6 0.2 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DUF4173 PF13777.6 EGG19987.1 - 0.5 9.8 8.1 0.073 12.5 1.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4173) Pox_A14 PF05767.12 EGG19987.1 - 2.7 8.2 8.8 0.44 10.7 0.8 2.8 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 SKG6 PF08693.10 EGG19988.1 - 0.22 11.0 2.9 0.44 10.0 2.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SCP2 PF02036.17 EGG19989.1 - 1.2e-50 170.2 3.8 2.2e-25 89.1 0.3 2.1 2 0 0 2 2 2 2 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EGG19989.1 - 6.3e-12 45.9 0.4 5e-05 23.6 0.1 2.2 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal PHA_gran_rgn PF09650.10 EGG19989.1 - 0.04 14.2 0.1 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) tRNA_anti-codon PF01336.25 EGG19989.1 - 0.11 12.5 0.3 10 6.2 0.0 2.4 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain RsfS PF02410.15 EGG19990.1 - 2.4e-18 66.4 0.0 1e-17 64.4 0.0 2.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation SPG48 PF14764.6 EGG19991.1 - 9.3e-33 113.2 2.3 5e-32 110.8 2.3 2.4 1 0 0 1 1 1 1 AP-5 complex subunit, vesicle trafficking Eapp_C PF10238.9 EGG19992.1 - 2.5e-48 164.0 10.9 2.5e-48 164.0 10.9 2.0 2 0 0 2 2 2 1 E2F-associated phosphoprotein C1_4 PF07975.12 EGG19992.1 - 0.16 12.2 5.0 0.21 11.9 1.2 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain IBR PF01485.21 EGG19992.1 - 6.7 7.0 10.9 0.43 10.8 1.2 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Thy1 PF02511.15 EGG19993.1 - 1.7e-51 174.7 0.2 2.5e-51 174.2 0.2 1.1 1 0 0 1 1 1 1 Thymidylate synthase complementing protein Serinc PF03348.15 EGG19994.1 - 5.9e-114 381.3 17.3 2.4e-113 379.3 17.3 1.6 1 1 0 1 1 1 1 Serine incorporator (Serinc) DUF3185 PF11381.8 EGG19994.1 - 0.00074 19.5 0.7 0.0089 16.0 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3185) UPF0370 PF13980.6 EGG19994.1 - 0.28 11.3 3.6 6.3 6.9 0.0 3.3 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0370) PPTA PF01239.22 EGG19994.1 - 0.61 9.9 3.8 1.6 8.6 0.1 2.6 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat MRAP PF15183.6 EGG19994.1 - 1.3 9.0 5.9 1.7 8.6 0.1 3.2 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family DUF4231 PF14015.6 EGG19994.1 - 9.2 6.8 11.0 4.5 7.8 0.2 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF4231) Complex1_LYR PF05347.15 EGG19995.1 - 7.5e-11 41.9 2.3 1.6e-10 40.9 2.3 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGG19995.1 - 0.0018 19.0 2.5 0.0025 18.5 2.5 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Zn_ribbon_SprT PF17283.2 EGG19996.1 - 0.29 11.1 3.7 13 5.8 0.3 3.5 3 0 0 3 3 3 0 SprT-like zinc ribbon domain GHMP_kinases_N PF00288.26 EGG19997.1 - 0.048 13.9 0.8 0.24 11.6 0.8 2.2 1 0 0 1 1 1 0 GHMP kinases N terminal domain MbeD_MobD PF04899.12 EGG19998.1 - 0.094 12.9 13.1 0.2 11.8 0.1 4.7 4 1 1 5 5 5 0 MbeD/MobD like DUF948 PF06103.11 EGG19998.1 - 1.5 9.1 8.9 1.8 8.9 0.9 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) LIM PF00412.22 EGG19999.1 - 3.4e-12 46.4 6.5 5.1e-12 45.8 6.5 1.3 1 0 0 1 1 1 1 LIM domain DUF737 PF05300.11 EGG19999.1 - 0.097 13.0 9.7 0.15 12.4 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) C1_1 PF00130.22 EGG19999.1 - 1.2 9.1 7.2 2.4 8.1 2.5 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CDC73_C PF05179.14 EGG20000.1 - 5.6e-47 159.3 3.6 5.6e-47 159.3 3.6 1.8 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 EGG20000.1 - 9.5e-26 90.8 2.9 3.7e-25 88.8 2.9 1.9 1 1 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal Selenoprotein_S PF06936.11 EGG20000.1 - 0.0011 18.8 3.5 0.0023 17.8 3.5 1.5 1 0 0 1 1 1 1 Selenoprotein S (SelS) Chorion_2 PF03964.15 EGG20000.1 - 0.0055 17.5 3.7 0.01 16.7 3.7 1.4 1 0 0 1 1 1 1 Chorion family 2 SR-25 PF10500.9 EGG20000.1 - 0.022 14.4 17.8 0.048 13.3 17.8 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PIEZO PF15917.5 EGG20000.1 - 0.032 13.7 2.5 0.058 12.9 2.5 1.5 1 0 0 1 1 1 0 Piezo FAM76 PF16046.5 EGG20000.1 - 0.59 9.4 7.7 0.98 8.7 7.7 1.3 1 0 0 1 1 1 0 FAM76 protein CCDC106 PF15794.5 EGG20000.1 - 0.81 9.4 11.3 1.7 8.3 11.3 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4718 PF15842.5 EGG20000.1 - 0.94 9.2 11.9 0.089 12.6 7.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) GREB1 PF15782.5 EGG20000.1 - 1.1 6.3 13.1 1.4 6.0 13.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FNIP PF05725.12 EGG20001.1 - 2.9e-161 523.5 59.8 3.7e-17 62.2 0.3 15.3 8 3 7 17 17 17 16 FNIP Repeat Pkinase PF00069.25 EGG20001.1 - 5.2e-16 58.8 0.0 8.7e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Phage_min_tail PF05939.13 EGG20001.1 - 1.8e-05 25.1 6.5 59 4.1 0.0 9.2 3 3 8 12 12 12 0 Phage minor tail protein Pkinase_Tyr PF07714.17 EGG20001.1 - 0.0023 17.3 0.0 0.29 10.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase AbiJ_NTD5 PF18865.1 EGG20001.1 - 0.17 11.7 1.5 70 3.3 0.0 4.9 3 2 0 4 4 4 0 AbiJ N-terminal domain 5 LRR_11 PF18831.1 EGG20001.1 - 1.8 8.2 37.3 5.3 6.7 0.0 11.9 13 0 0 13 13 13 0 Leucine-rich repeat zf-RING_2 PF13639.6 EGG20002.1 - 4.7e-10 39.6 2.9 9.8e-10 38.6 2.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG20002.1 - 1.4e-08 34.6 0.3 6.4e-08 32.5 0.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGG20002.1 - 3.6e-08 33.6 2.9 1.3e-07 31.8 2.9 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGG20002.1 - 1.9e-07 30.8 2.9 5e-07 29.5 2.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG20002.1 - 1.7e-06 27.8 1.3 3.5e-06 26.8 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG20002.1 - 1.8e-06 27.8 3.1 3.4e-06 26.9 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGG20002.1 - 6.2e-06 26.0 4.1 1.6e-05 24.7 4.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG20002.1 - 0.00017 21.4 3.5 0.00042 20.1 3.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGG20002.1 - 0.0017 18.4 0.6 0.0046 17.0 0.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EGG20002.1 - 0.0028 17.4 2.6 0.011 15.4 2.6 2.1 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 EGG20002.1 - 0.0032 17.6 2.1 0.012 15.8 2.1 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EGG20002.1 - 0.067 13.0 3.2 0.055 13.3 1.0 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 EGG20002.1 - 0.13 11.9 1.0 0.64 9.7 0.4 2.2 2 0 0 2 2 2 0 P-11 zinc finger HEAT PF02985.22 EGG20003.1 - 0.005 17.0 0.1 9.8 6.7 0.1 4.1 3 0 0 3 3 3 2 HEAT repeat SlyX PF04102.12 EGG20003.1 - 0.092 13.4 0.1 0.092 13.4 0.1 3.8 4 0 0 4 4 4 0 SlyX TFIIA PF03153.13 EGG20003.1 - 1.1 9.1 26.5 0.31 11.0 15.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3430 PF11912.8 EGG20004.1 - 1.6e-06 28.3 10.9 2e-06 28.0 10.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Pkinase PF00069.25 EGG20005.1 - 5.6e-66 222.6 0.1 7.3e-66 222.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20005.1 - 3e-19 69.3 0.0 4.7e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG20005.1 - 7e-08 32.7 0.0 1.1e-06 28.7 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGG20005.1 - 0.007 15.2 0.1 0.013 14.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 EGG20005.1 - 0.031 13.9 0.4 0.061 12.9 0.4 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EGG20005.1 - 0.055 12.8 0.3 0.093 12.1 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_U4 PF03419.13 EGG20006.1 - 0.0042 16.4 0.3 0.0051 16.2 0.3 1.1 1 0 0 1 1 1 1 Sporulation factor SpoIIGA SPC25 PF06703.11 EGG20006.1 - 0.016 15.0 2.6 0.024 14.4 2.6 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2721 PF11026.8 EGG20006.1 - 0.019 14.9 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF5345 PF17280.2 EGG20006.1 - 0.046 13.7 0.3 0.077 13.0 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Mito_carr PF00153.27 EGG20007.1 - 4.2e-70 231.8 1.0 6.4e-26 90.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4211 PF13926.6 EGG20008.1 - 2.1e-26 92.7 3.1 2.1e-26 92.7 3.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) Ribosomal_L10 PF00466.20 EGG20010.1 - 8.9e-17 61.1 0.1 1.3e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 EGG20010.1 - 8.8e-16 57.7 0.0 1.3e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P InvH PF04741.12 EGG20010.1 - 0.022 14.7 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 InvH outer membrane lipoprotein DUF4252 PF14060.6 EGG20010.1 - 0.097 12.6 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) Skp1 PF01466.19 EGG20011.1 - 9.2e-30 102.5 1.5 9.2e-30 102.5 1.5 1.9 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EGG20011.1 - 4.5e-28 97.2 1.4 7.6e-28 96.5 0.7 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Vac14_Fab1_bd PF12755.7 EGG20012.1 - 0.0004 20.9 0.3 3.2 8.4 0.0 3.9 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGG20012.1 - 0.00042 20.4 12.3 0.32 11.0 0.6 4.3 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGG20012.1 - 0.0014 19.1 0.0 0.93 10.1 0.0 3.1 2 0 0 2 2 2 2 HEAT-like repeat HEAT PF02985.22 EGG20012.1 - 0.018 15.2 0.1 34 5.1 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat DUF5123 PF17161.4 EGG20012.1 - 0.68 11.0 6.2 0.22 12.6 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5123) POX PF07526.11 EGG20012.1 - 1.7 9.2 4.7 2.9 8.5 3.4 2.1 1 1 1 2 2 2 0 Associated with HOX DUF410 PF04190.13 EGG20013.1 - 0.034 14.0 3.0 0.036 13.9 1.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF410) Mon1 PF03164.14 EGG20014.1 - 5.3e-10 38.9 3.7 6.6e-10 38.6 2.7 1.5 2 0 0 2 2 2 1 Trafficking protein Mon1 PG_binding_1 PF01471.18 EGG20014.1 - 1.3e-05 25.3 0.0 2.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Rac1 PF09632.10 EGG20014.1 - 0.036 13.2 0.4 0.066 12.4 0.1 1.5 2 0 0 2 2 2 0 Rac1-binding domain Yuri_gagarin PF15934.5 EGG20014.1 - 0.041 13.7 1.0 0.084 12.7 1.0 1.5 1 0 0 1 1 1 0 Yuri gagarin Stk19 PF10494.9 EGG20016.1 - 4.4e-13 49.5 0.3 8e-13 48.6 0.3 1.3 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF4423 PF14394.6 EGG20016.1 - 0.14 11.8 0.0 0.14 11.8 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4423) Mucin PF01456.17 EGG20016.1 - 0.57 10.2 12.1 0.19 11.7 6.4 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.8 EGG20016.1 - 2.4 8.2 8.9 2.8 7.9 5.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ank_2 PF12796.7 EGG20017.1 - 7.1e-28 97.0 14.2 6.8e-09 36.2 0.3 6.6 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG20017.1 - 1.7e-23 82.7 18.4 4.1e-05 24.0 0.3 9.7 7 4 2 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG20017.1 - 1.3e-16 60.4 14.0 0.0069 16.7 0.1 10.7 6 4 5 11 11 11 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG20017.1 - 2.7e-16 58.0 16.2 0.17 12.5 0.0 12.9 12 1 2 14 14 14 4 Ankyrin repeat Ank PF00023.30 EGG20017.1 - 0.00036 20.8 9.2 38 5.0 0.0 7.5 7 0 0 7 7 7 0 Ankyrin repeat RPA43_OB PF17875.1 EGG20018.1 - 0.0056 17.3 2.2 0.0064 17.1 2.2 1.0 1 0 0 1 1 1 1 RPA43 OB domain in RNA Pol I EIIBC-GUT_N PF03612.14 EGG20018.1 - 0.045 13.5 4.1 0.048 13.4 4.1 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4834 PF16118.5 EGG20018.1 - 0.083 13.9 5.6 0.084 13.8 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 EGG20018.1 - 0.084 12.5 20.1 0.089 12.4 20.1 1.0 1 0 0 1 1 1 0 Spt20 family Peptidase_S49_N PF08496.10 EGG20018.1 - 0.089 12.9 4.3 0.091 12.8 4.3 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal adh_short_C2 PF13561.6 EGG20018.1 - 0.1 12.2 0.0 0.1 12.1 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF5349 PF17298.2 EGG20018.1 - 0.32 10.7 12.6 0.33 10.7 12.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF4199 PF13858.6 EGG20018.1 - 0.34 11.3 5.5 0.37 11.2 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) ATP-synt_E PF05680.12 EGG20018.1 - 0.41 11.0 5.9 0.5 10.7 5.9 1.1 1 0 0 1 1 1 0 ATP synthase E chain Presenilin PF01080.17 EGG20018.1 - 2.3 6.9 5.2 2.4 6.8 5.2 1.0 1 0 0 1 1 1 0 Presenilin Med3 PF11593.8 EGG20018.1 - 3.8 6.6 15.9 3.8 6.6 15.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 EGG20018.1 - 4.4 7.2 17.4 4.7 7.1 17.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5421 PF17458.2 EGG20018.1 - 5.4 6.3 13.5 5.4 6.3 13.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5421) MscS_TM PF12794.7 EGG20018.1 - 6.8 5.4 5.4 7.9 5.2 5.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 TIG PF01833.24 EGG20020.1 - 1.4e-42 143.6 86.0 1.2e-11 44.5 3.5 12.8 13 0 0 13 13 13 10 IPT/TIG domain DNase_II PF03265.15 EGG20020.1 - 1.1e-26 93.9 5.1 1.1e-16 61.1 0.2 3.1 3 0 0 3 3 3 2 Deoxyribonuclease II TIG PF01833.24 EGG20021.1 - 2.2e-42 143.0 50.8 1e-11 44.7 2.2 9.6 8 0 0 8 8 8 6 IPT/TIG domain DNase_II PF03265.15 EGG20021.1 - 5.5e-22 78.5 2.5 5.5e-22 78.5 2.5 2.6 2 1 0 2 2 2 1 Deoxyribonuclease II RabGAP-TBC PF00566.18 EGG20022.1 - 2.3e-21 76.5 8.2 5.3e-14 52.4 0.7 6.1 6 1 0 6 6 6 2 Rab-GTPase-TBC domain Dimerisation2 PF16864.5 EGG20022.1 - 0.23 11.5 1.4 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Dimerisation domain VPS9 PF02204.18 EGG20023.1 - 4.5e-28 97.5 0.1 1.7e-27 95.7 0.1 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.24 EGG20023.1 - 2.3e-17 63.0 5.8 6.3e-17 61.6 1.1 3.9 4 0 0 4 4 4 1 PX domain Ras PF00071.22 EGG20023.1 - 1.7e-07 30.9 0.0 4.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Ras family DUF5601 PF18151.1 EGG20023.1 - 0.0017 18.6 0.9 0.0089 16.3 0.9 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) Roc PF08477.13 EGG20023.1 - 0.017 15.3 0.0 0.081 13.1 0.0 2.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DMA PF03474.14 EGG20023.1 - 0.023 14.3 0.0 0.066 12.8 0.0 1.8 1 0 0 1 1 1 0 DMRTA motif eIF-5a PF01287.20 EGG20024.1 - 2.2e-15 56.5 0.3 3e-15 56.1 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold LolA_2 PF16584.5 EGG20024.1 - 0.011 15.6 0.0 3.6 7.4 0.0 2.1 1 1 1 2 2 2 0 Outer membrane lipoprotein carrier protein LolA Vps16_C PF04840.12 EGG20026.1 - 1.9e-83 280.2 1.2 2.6e-83 279.7 1.2 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 EGG20026.1 - 5.5e-73 246.1 0.0 7.2e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Pro_isomerase PF00160.21 EGG20027.1 - 1.2e-42 145.9 0.0 3.5e-42 144.4 0.0 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MLD PF11647.8 EGG20027.1 - 0.04 14.2 0.0 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 Membrane Localization Domain XAP5 PF04921.14 EGG20027.1 - 0.19 11.5 13.3 0.09 12.6 10.9 1.6 1 1 0 1 1 1 0 XAP5, circadian clock regulator Ebola_NP PF05505.12 EGG20027.1 - 0.4 8.9 14.1 0.14 10.4 11.2 1.4 1 1 0 1 1 1 0 Ebola nucleoprotein DUF4551 PF15087.6 EGG20027.1 - 1 8.1 9.1 1.3 7.7 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PCI PF01399.27 EGG20028.1 - 7.4e-25 87.5 1.0 7.4e-25 87.5 1.0 2.8 2 1 1 3 3 3 1 PCI domain TPR_7 PF13176.6 EGG20028.1 - 0.0087 16.0 0.0 59 4.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4486 PF14858.6 EGG20028.1 - 0.029 12.9 4.7 0.012 14.1 1.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4486) TPR_8 PF13181.6 EGG20028.1 - 0.041 14.1 6.3 31 5.1 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGG20028.1 - 0.17 11.7 3.1 4.2 7.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG20028.1 - 0.23 11.6 1.7 28 5.1 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat DpnI_C PF17726.1 EGG20028.1 - 1.9 8.7 6.8 0.59 10.3 0.1 3.1 4 0 0 4 4 4 0 Dam-replacing HTH domain Cystatin PF00031.21 EGG20029.1 - 3.4e-09 36.9 0.5 3.9e-09 36.7 0.5 1.1 1 0 0 1 1 1 1 Cystatin domain Dimer_Tnp_hAT PF05699.14 EGG20030.1 - 7.5e-11 41.7 1.2 1.6e-10 40.6 0.1 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region EAP30 PF04157.16 EGG20030.1 - 4.5 6.5 8.5 7.8 5.7 4.8 2.4 2 0 0 2 2 2 0 EAP30/Vps36 family Pkinase_Tyr PF07714.17 EGG20032.1 - 2.4e-91 305.6 0.0 8.3e-58 195.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EGG20032.1 - 2.7e-85 286.0 0.0 2.7e-55 187.6 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain FHA PF00498.26 EGG20032.1 - 3.7e-05 24.0 0.4 0.00035 20.9 0.4 2.7 1 1 0 1 1 1 1 FHA domain FHA_2 PF17913.1 EGG20032.1 - 0.0045 17.2 0.0 0.023 14.9 0.0 2.2 2 0 0 2 2 2 1 FHA domain Forkhead PF00250.18 EGG20032.1 - 0.015 15.5 2.3 0.038 14.2 2.3 1.7 1 0 0 1 1 1 0 Forkhead domain Eaf7 PF07904.13 EGG20032.1 - 0.23 11.8 3.4 0.81 10.1 3.4 1.9 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 DUF3439 PF11921.8 EGG20032.1 - 1.1 9.3 5.4 3.3 7.7 5.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Histone PF00125.24 EGG20033.1 - 2.1e-14 54.0 0.5 6.3e-07 29.8 0.1 2.1 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGG20033.1 - 3.2e-06 27.3 0.4 0.019 15.2 0.0 2.2 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 EGG20033.1 - 1.8e-05 24.8 0.6 0.22 11.6 0.1 2.3 2 0 0 2 2 2 2 hTAFII28-like protein conserved region TAF PF02969.17 EGG20033.1 - 0.00028 21.0 0.2 0.026 14.7 0.2 2.2 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 EGG20033.1 - 0.00045 20.3 0.4 0.14 12.3 0.0 2.3 2 1 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 EGG20033.1 - 0.055 13.5 0.0 9.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Pkinase PF00069.25 EGG20034.1 - 5.1e-25 88.3 0.0 5.7e-22 78.3 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20034.1 - 2.9e-17 62.8 0.1 7.3e-13 48.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EGG20034.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGG20034.1 - 0.03 13.1 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pex24p PF06398.11 EGG20034.1 - 0.032 13.2 4.9 0.048 12.6 4.9 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PHD PF00628.29 EGG20037.1 - 3.7e-14 52.3 25.8 5.9e-09 35.7 12.5 2.6 2 0 0 2 2 2 2 PHD-finger Myb_DNA-bind_6 PF13921.6 EGG20037.1 - 6.9e-05 23.0 0.0 0.0004 20.6 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGG20037.1 - 0.00076 19.6 0.0 0.0082 16.3 0.0 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain PHD_4 PF16866.5 EGG20037.1 - 0.0091 16.1 8.4 0.0091 16.1 8.4 3.3 1 1 1 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 EGG20037.1 - 0.96 9.4 14.8 6.7 6.7 0.5 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 EGG20038.1 - 0.00014 21.7 13.3 0.00014 21.7 13.3 4.6 5 0 0 5 5 5 1 PHD-finger EVE PF01878.18 EGG20038.1 - 0.00065 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 EVE domain C1_1 PF00130.22 EGG20038.1 - 0.0038 17.1 5.8 0.0038 17.1 5.8 3.4 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Dicty_CTDC PF00526.18 EGG20038.1 - 0.007 16.2 5.9 0.007 16.2 5.9 6.4 7 0 0 7 7 7 2 Dictyostelium (slime mold) repeat Cwf_Cwc_15 PF04889.12 EGG20038.1 - 0.99 9.1 11.5 1.8 8.3 11.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EGG20038.1 - 1.5 6.9 9.9 2.6 6.2 9.9 1.2 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 EGG20038.1 - 2 8.2 12.2 0.035 14.0 5.1 1.5 2 0 0 2 2 2 0 Myc amino-terminal region Paramyxo_ncap PF00973.19 EGG20038.1 - 5.6 5.8 6.1 9.1 5.1 6.1 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CENP-B_dimeris PF09026.10 EGG20038.1 - 5.9 7.3 12.5 1.8 9.0 6.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pkinase PF00069.25 EGG20039.1 - 2.1e-63 214.2 1.0 1.9e-39 135.6 0.3 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20039.1 - 5.5e-30 104.5 0.0 3e-22 79.2 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase PH PF00169.29 EGG20039.1 - 4.3e-18 65.8 2.8 1e-17 64.5 0.0 3.2 3 0 0 3 3 3 1 PH domain PX PF00787.24 EGG20039.1 - 2.2e-17 63.0 1.2 7.2e-17 61.4 1.2 1.9 1 0 0 1 1 1 1 PX domain DUF4470 PF14737.6 EGG20039.1 - 1.6e-09 37.8 0.0 4.6e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) PH_8 PF15409.6 EGG20039.1 - 8e-05 22.9 0.0 0.00024 21.3 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain TPR_12 PF13424.6 EGG20039.1 - 9.8e-05 22.6 0.1 0.006 16.8 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG20039.1 - 0.0024 17.6 1.2 1 9.3 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat PH_9 PF15410.6 EGG20039.1 - 0.0026 18.1 0.2 0.23 11.8 0.2 3.2 1 1 0 1 1 1 1 Pleckstrin homology domain TPR_2 PF07719.17 EGG20039.1 - 0.0029 17.6 0.3 2.6 8.4 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Kinase-like PF14531.6 EGG20039.1 - 0.0042 16.4 0.0 0.81 8.9 0.0 2.6 2 0 0 2 2 2 1 Kinase-like PH_11 PF15413.6 EGG20039.1 - 0.0065 16.9 7.1 0.0074 16.7 1.0 3.5 2 1 0 2 2 2 1 Pleckstrin homology domain TPR_11 PF13414.6 EGG20039.1 - 0.0088 15.7 1.1 0.27 10.9 0.8 2.5 2 0 0 2 2 2 1 TPR repeat APH PF01636.23 EGG20039.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ANAPC3 PF12895.7 EGG20039.1 - 0.013 15.7 0.2 0.038 14.2 0.2 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGG20039.1 - 0.043 14.3 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Kdo PF06293.14 EGG20039.1 - 0.048 13.0 0.0 0.15 11.4 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_8 PF13181.6 EGG20039.1 - 0.052 13.8 1.4 6.7 7.2 0.4 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG20039.1 - 0.17 12.0 1.2 18 5.6 0.0 3.2 2 1 1 3 3 2 0 Tetratricopeptide repeat Peptidase_C1 PF00112.23 EGG20044.1 - 3.9e-63 213.4 0.7 6.3e-63 212.8 0.7 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG20044.1 - 6.3e-12 45.8 1.9 1.2e-11 44.9 1.9 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGG20044.1 - 0.00043 19.2 0.1 0.027 13.3 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family DUF3446 PF11928.8 EGG20044.1 - 0.27 11.5 22.4 3 8.2 14.0 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain P_C PF06640.11 EGG20044.1 - 4.6 7.3 6.2 3.2 7.8 0.1 2.2 2 0 0 2 2 2 0 P protein C-terminus Sortilin-Vps10 PF15902.5 EGG20045.1 - 4.9e-68 230.0 0.4 6.7e-68 229.5 0.4 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EGG20045.1 - 1.2e-19 71.3 0.0 1.8e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EGG20045.1 - 4.6e-06 25.8 22.1 0.28 11.3 0.3 7.7 7 0 0 7 7 7 3 BNR/Asp-box repeat BNR_6 PF15899.5 EGG20045.1 - 0.0075 16.2 1.4 0.52 10.5 0.0 4.0 4 0 0 4 4 4 1 BNR-Asp box repeat QCR10 PF09796.9 EGG20045.1 - 0.061 13.4 0.2 0.19 11.8 0.2 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) CbtA PF09490.10 EGG20046.1 - 0.0085 15.9 0.2 0.013 15.3 0.2 1.2 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) SARAF PF06682.12 EGG20046.1 - 0.048 13.3 0.5 0.098 12.3 0.0 1.7 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis GCV_T PF01571.21 EGG20047.1 - 2e-86 289.5 0.2 2.5e-86 289.2 0.2 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EGG20047.1 - 2.1e-16 59.6 0.3 3.9e-16 58.7 0.3 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 EGG20047.1 - 0.00036 20.7 0.0 0.00079 19.6 0.0 1.6 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family DUF3659 PF12396.8 EGG20047.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) G8 PF10162.9 EGG20047.1 - 0.12 12.4 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 G8 domain adh_short PF00106.25 EGG20048.1 - 6.7e-38 130.1 0.1 8.3e-38 129.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG20048.1 - 1.8e-21 76.7 0.0 2.3e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG20048.1 - 5.5e-10 39.4 0.1 7.8e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 KR domain EIIBC-GUT_N PF03612.14 EGG20048.1 - 0.017 14.8 0.4 0.033 13.9 0.1 1.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Epimerase PF01370.21 EGG20048.1 - 0.034 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SprT-like PF10263.9 EGG20049.1 - 1.4e-11 44.2 0.1 5.7e-11 42.3 0.1 2.0 1 0 0 1 1 1 1 SprT-like family GDPD PF03009.17 EGG20050.1 - 1.1e-54 185.9 0.0 8.6e-54 183.0 0.0 2.5 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EGG20050.1 - 2.8e-33 114.4 5.0 3.7e-12 46.7 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG20050.1 - 1.6e-31 108.3 1.9 6e-07 29.9 0.0 6.7 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG20050.1 - 3.8e-24 82.1 1.6 0.0051 17.2 0.0 8.2 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 EGG20050.1 - 3.6e-20 71.4 6.0 0.0019 18.5 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EGG20050.1 - 4.7e-18 65.0 3.9 2.3e-05 24.6 0.0 7.3 2 1 6 8 8 8 5 Ankyrin repeats (many copies) CBM_20 PF00686.19 EGG20050.1 - 3.1e-14 52.6 0.1 8.4e-14 51.3 0.1 1.7 1 0 0 1 1 1 1 Starch binding domain SPX PF03105.19 EGG20050.1 - 1.5e-07 31.7 0.2 1.5e-07 31.7 0.2 4.7 3 1 2 5 5 5 2 SPX domain Plectin PF00681.20 EGG20050.1 - 0.036 13.9 0.1 0.54 10.2 0.0 2.4 2 0 0 2 2 2 0 Plectin repeat DUF2520 PF10728.9 EGG20050.1 - 0.18 11.6 0.1 0.63 9.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) SUIM_assoc PF16619.5 EGG20050.1 - 3.7 7.7 10.6 0.29 11.2 1.9 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PH_12 PF16457.5 EGG20050.1 - 8 7.0 9.1 0.7 10.4 0.5 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain Rab3-GTPase_cat PF13890.6 EGG20051.1 - 2.9e-47 160.3 0.1 8.1e-47 158.9 0.1 1.8 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit SUIM_assoc PF16619.5 EGG20051.1 - 2.9 8.0 11.3 9 6.5 0.6 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pyr_redox_2 PF07992.14 EGG20052.1 - 1.4e-17 63.9 0.1 2e-11 43.7 0.0 2.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG20052.1 - 0.0025 17.8 0.0 0.39 10.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EGG20052.1 - 0.0072 15.2 0.0 0.015 14.1 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 EGG20052.1 - 0.011 16.0 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG20052.1 - 0.011 15.3 0.0 0.043 13.4 0.0 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase Lactamase_B PF00753.27 EGG20053.1 - 6.7e-15 55.6 0.1 1e-14 55.0 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily UPF0051 PF01458.17 EGG20053.1 - 0.006 16.3 2.6 0.012 15.3 2.6 1.5 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Lactamase_B_2 PF12706.7 EGG20053.1 - 0.025 14.1 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain OTU PF02338.19 EGG20054.1 - 2.9e-18 66.6 0.1 6e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGG20054.1 - 0.00044 19.8 10.3 0.011 15.2 0.2 3.2 3 0 0 3 3 3 2 Peptidase C65 Otubain SR-25 PF10500.9 EGG20054.1 - 7.2 6.1 37.8 2.8 7.5 15.0 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DFF40 PF09230.10 EGG20055.1 - 0.00016 21.4 1.5 0.00027 20.7 1.5 1.3 1 0 0 1 1 1 1 DNA fragmentation factor 40 kDa DUF4701 PF15773.5 EGG20055.1 - 0.015 14.4 1.9 0.021 13.8 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4701) zf-CCHH PF10283.9 EGG20056.1 - 6 6.9 15.6 2.4 8.2 1.5 3.8 3 0 0 3 3 3 0 PBZ domain zf-CCCH_2 PF14608.6 EGG20057.1 - 0.041 14.4 0.3 0.041 14.4 0.3 9.5 11 0 0 11 11 11 0 RNA-binding, Nab2-type zinc finger Dickkopf_N PF04706.12 EGG20058.1 - 0.0015 19.0 3.0 0.0015 19.0 3.0 7.1 4 3 2 6 6 6 4 Dickkopf N-terminal cysteine-rich region EB PF01683.18 EGG20058.1 - 0.022 15.1 13.7 0.022 15.1 13.7 7.2 1 1 3 4 4 4 0 EB module Dickkopf_N PF04706.12 EGG20059.1 - 0.0028 18.1 1.9 0.0028 18.1 1.9 7.3 4 3 2 6 6 6 2 Dickkopf N-terminal cysteine-rich region MobB PF03205.14 EGG20060.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 EGG20060.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_35 PF14516.6 EGG20060.1 - 0.025 13.4 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_7 PF12775.7 EGG20060.1 - 0.034 13.7 0.1 0.046 13.2 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 EGG20060.1 - 0.049 13.6 0.1 0.069 13.2 0.1 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 EGG20060.1 - 0.1 12.5 0.1 0.14 12.0 0.1 1.3 1 1 0 1 1 1 0 NTPase DNA_pol_B_N PF18094.1 EGG20061.1 - 0.11 13.1 0.5 0.79 10.3 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase beta N-terminal domain Activator_LAG-3 PF11498.8 EGG20061.1 - 0.42 9.5 16.1 0.58 9.1 16.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TsaE PF02367.17 EGG20062.1 - 0.0055 16.7 0.0 0.0088 16.1 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EGG20062.1 - 0.0086 16.5 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain VirE PF05272.11 EGG20062.1 - 0.0097 15.7 0.4 0.08 12.7 0.1 2.2 1 1 1 2 2 2 1 Virulence-associated protein E AAA_23 PF13476.6 EGG20062.1 - 0.015 15.8 1.1 0.021 15.3 0.2 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGG20062.1 - 0.015 15.8 0.0 0.026 15.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.13 EGG20062.1 - 0.025 13.7 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EGG20062.1 - 0.072 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 EGG20062.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase RHSP PF07999.11 EGG20063.1 - 0.0036 16.2 0.1 0.017 13.9 0.1 2.0 1 1 0 1 1 1 1 Retrotransposon hot spot protein PrgU PF09627.10 EGG20063.1 - 0.0047 16.9 0.8 0.014 15.4 0.8 1.8 1 0 0 1 1 1 1 PrgU-like protein AAA_16 PF13191.6 EGG20063.1 - 0.032 14.6 1.8 0.21 12.0 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EGG20063.1 - 0.13 12.6 1.0 1.2 9.4 0.0 3.0 3 1 1 4 4 4 0 AAA domain ATPase PF06745.13 EGG20063.1 - 0.31 10.3 0.0 0.31 10.3 0.0 3.6 4 1 1 5 5 5 0 KaiC DUF3439 PF11921.8 EGG20063.1 - 3 7.8 11.7 7.1 6.6 11.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SAM_2 PF07647.17 EGG20065.1 - 7.5e-07 29.2 0.0 9.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGG20065.1 - 0.00057 20.3 0.0 0.0009 19.6 0.0 1.4 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 EGG20065.1 - 0.02 15.1 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_PNT PF02198.16 EGG20065.1 - 0.023 14.6 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF3047 PF11249.8 EGG20065.1 - 0.036 13.5 0.1 0.046 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) FlbT PF07378.11 EGG20065.1 - 0.11 12.6 0.1 0.16 12.0 0.1 1.5 1 1 0 1 1 1 0 Flagellar protein FlbT SAM_PNT PF02198.16 EGG20067.1 - 1.3e-06 28.2 0.1 2.8e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain DUF2124 PF09897.9 EGG20067.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) MADF_DNA_bdg PF10545.9 EGG20067.1 - 0.2 12.0 2.9 0.82 10.0 0.6 2.7 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Y_phosphatase2 PF03162.13 EGG20068.1 - 2.3e-61 206.2 0.0 3e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGG20068.1 - 5.6e-07 29.8 0.0 8.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EGG20068.1 - 0.00025 20.8 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG20068.1 - 0.0061 16.2 0.0 0.0093 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LIM PF00412.22 EGG20069.1 - 9.6e-08 32.1 8.6 1.9e-07 31.2 8.6 1.5 1 0 0 1 1 1 1 LIM domain TPR_1 PF00515.28 EGG20070.1 - 8.1e-08 31.8 0.6 0.0026 17.5 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG20070.1 - 3.4e-07 29.9 0.4 0.03 14.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 EGG20070.1 - 0.00015 21.7 0.9 0.24 11.5 0.2 2.8 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain p25-alpha PF05517.12 EGG20070.1 - 0.013 15.7 1.7 0.013 15.7 1.7 2.3 2 1 0 2 2 2 0 p25-alpha Rtt102p PF09510.10 EGG20070.1 - 0.019 15.2 4.6 0.019 15.2 4.6 2.4 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein TPR_12 PF13424.6 EGG20070.1 - 0.022 15.0 0.3 18 5.7 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EGG20070.1 - 0.043 13.2 3.9 1.5 8.1 0.1 2.2 1 1 1 2 2 2 0 Coatomer epsilon subunit TPR_8 PF13181.6 EGG20070.1 - 0.061 13.6 1.1 37 4.9 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Tubulin_C PF03953.17 EGG20071.1 - 6.1e-42 142.8 3.2 5.6e-38 129.9 1.2 2.5 2 0 0 2 2 2 2 Tubulin C-terminal domain Tubulin PF00091.25 EGG20071.1 - 5e-15 56.2 0.3 2.4e-12 47.5 0.0 2.7 2 1 1 3 3 3 2 Tubulin/FtsZ family, GTPase domain HeH PF12949.7 EGG20071.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain Pet191_N PF10203.9 EGG20072.1 - 0.29 11.5 15.9 0.56 10.5 0.2 3.3 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 SOG2 PF10428.9 EGG20072.1 - 0.75 8.9 30.8 1.1 8.4 30.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4551 PF15087.6 EGG20072.1 - 6.1 5.6 12.9 8.2 5.1 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Peptidase_S64 PF08192.11 EGG20072.1 - 6.2 5.2 15.4 8.2 4.8 15.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Folliculin PF11704.8 EGG20073.1 - 0.00066 19.6 2.7 0.00066 19.6 2.7 5.1 5 2 0 5 5 5 1 Vesicle coat protein involved in Golgi to plasma membrane transport MerC PF03203.14 EGG20074.1 - 0.0056 17.1 0.2 0.54 10.7 0.1 2.6 1 1 0 2 2 2 1 MerC mercury resistance protein YajC PF02699.15 EGG20074.1 - 0.012 15.5 0.2 4.2 7.3 0.2 2.6 2 0 0 2 2 2 0 Preprotein translocase subunit DUF2615 PF11027.8 EGG20074.1 - 0.099 12.8 0.4 17 5.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) Ycf70 PF17382.2 EGG20074.1 - 0.94 9.9 0.0 0.94 9.9 0.0 2.6 2 2 0 2 2 2 0 Uncharacterized Ycf70-like FKBP_C PF00254.28 EGG20075.1 - 2.1e-07 31.1 0.0 1.4e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 EGG20075.1 - 0.00015 21.4 0.3 0.032 14.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG20075.1 - 0.00053 19.9 0.9 1.3 9.3 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG20075.1 - 0.011 16.0 0.2 0.26 11.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Epimerase PF01370.21 EGG20076.1 - 5e-25 88.3 0.0 3e-24 85.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG20076.1 - 2.5e-19 69.9 0.0 1.2e-08 34.8 0.0 2.6 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGG20076.1 - 7e-14 51.5 0.0 6.7e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGG20076.1 - 3.6e-13 49.3 0.1 1.2e-11 44.2 0.1 2.7 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EGG20076.1 - 1.3e-06 27.8 0.0 3e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGG20076.1 - 8.4e-06 25.8 0.0 0.064 13.1 0.0 2.3 2 0 0 2 2 2 2 NAD(P)H-binding RmlD_sub_bind PF04321.17 EGG20076.1 - 2.1e-05 23.8 0.0 0.073 12.2 0.1 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain KR PF08659.10 EGG20076.1 - 0.00069 19.6 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Sporozoite_P67 PF05642.11 EGG20076.1 - 0.002 16.3 2.7 0.0024 16.0 2.7 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF4611 PF15387.6 EGG20076.1 - 0.012 15.8 1.7 0.023 14.9 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NmrA PF05368.13 EGG20076.1 - 0.016 14.8 0.0 0.033 13.7 0.0 1.7 1 0 0 1 1 1 0 NmrA-like family Mem_trans PF03547.18 EGG20076.1 - 0.021 13.2 0.0 0.021 13.2 0.0 1.2 1 0 0 1 1 1 0 Membrane transport protein adh_short PF00106.25 EGG20076.1 - 0.052 13.0 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Macoilin PF09726.9 EGG20076.1 - 0.055 12.0 1.4 0.066 11.8 1.4 1.1 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 EGG20076.1 - 0.087 11.1 5.4 0.12 10.7 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 EGG20076.1 - 0.094 11.6 5.2 0.13 11.1 5.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SDA1 PF05285.12 EGG20076.1 - 0.12 11.8 6.3 0.19 11.1 6.3 1.3 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 EGG20076.1 - 0.37 10.4 4.5 0.71 9.5 4.5 1.4 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 EGG20076.1 - 0.45 8.7 8.0 0.59 8.3 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family PNISR PF15996.5 EGG20076.1 - 0.66 10.2 5.3 1.2 9.4 5.3 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF4614 PF15391.6 EGG20076.1 - 0.83 9.6 10.8 1.3 9.0 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) BUD22 PF09073.10 EGG20076.1 - 1 8.7 14.2 1.6 8.0 14.2 1.2 1 0 0 1 1 1 0 BUD22 Tub_N PF16322.5 EGG20076.1 - 1.1 9.6 12.7 2 8.8 12.7 1.3 1 0 0 1 1 1 0 Tubby N-terminal CobT PF06213.12 EGG20076.1 - 1.2 8.5 6.6 1.6 8.0 6.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT AF-4 PF05110.13 EGG20076.1 - 2.7 6.0 15.2 3.8 5.5 15.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DNA_pol_phi PF04931.13 EGG20076.1 - 4.4 5.3 10.8 6.3 4.8 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EGG20076.1 - 4.8 6.4 8.3 7.8 5.7 8.3 1.3 1 0 0 1 1 1 0 NOA36 protein SIR2 PF02146.17 EGG20077.1 - 7.6e-51 172.5 0.0 2.8e-50 170.7 0.0 2.0 2 0 0 2 2 2 1 Sir2 family zf-UBP PF02148.19 EGG20077.1 - 0.0051 17.1 15.3 0.011 16.1 12.1 2.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein AhpC-TSA PF00578.21 EGG20078.1 - 4.8e-37 126.6 0.1 5.9e-37 126.4 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGG20078.1 - 3e-21 75.7 0.0 3.6e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EGG20078.1 - 0.0047 17.0 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme SCO1-SenC PF02630.14 EGG20078.1 - 0.031 14.2 0.3 0.056 13.3 0.3 1.5 1 1 0 1 1 1 0 SCO1/SenC EF-hand_7 PF13499.6 EGG20079.1 - 2.9e-19 69.3 28.8 4.4e-08 33.5 1.6 3.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGG20079.1 - 2.7e-17 61.1 14.9 9.1e-05 22.1 0.0 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 EGG20079.1 - 5.3e-17 60.0 16.7 1.6e-05 24.1 0.0 5.2 5 1 0 5 5 5 4 EF hand EF-hand_5 PF13202.6 EGG20079.1 - 2.5e-13 48.8 15.6 0.00011 21.5 0.0 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 EGG20079.1 - 3.2e-08 33.3 12.4 0.029 14.2 0.0 4.6 4 1 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGG20079.1 - 0.00057 20.2 2.8 0.56 10.5 0.5 3.6 2 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGG20079.1 - 0.0073 16.2 3.3 2.6 8.1 0.0 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EGG20079.1 - 0.025 14.8 1.1 1.6 9.0 0.0 3.0 3 0 0 3 3 3 0 Dockerin type I domain DUF3127 PF11325.8 EGG20079.1 - 0.029 14.6 0.1 0.059 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) EF-hand_10 PF14788.6 EGG20079.1 - 0.061 13.2 5.2 4 7.4 0.1 3.4 3 0 0 3 3 3 0 EF hand EF-hand_11 PF08976.11 EGG20079.1 - 0.18 12.7 0.5 8 7.4 0.1 2.7 1 1 1 2 2 2 0 EF-hand domain TraB PF01963.17 EGG20080.1 - 3e-08 33.9 1.4 8.8e-08 32.4 1.4 1.9 1 1 0 1 1 1 1 TraB family DUF4422 PF14393.6 EGG20080.1 - 0.061 13.2 0.3 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4422) VCBS PF13517.6 EGG20081.1 - 2.2e-31 108.2 26.2 8e-12 45.6 4.4 5.2 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UnbV_ASPIC PF07593.12 EGG20081.1 - 8.6e-14 51.3 0.0 1.6e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 ASPIC and UnbV FG-GAP PF01839.23 EGG20081.1 - 1.3e-07 31.6 26.0 0.22 11.7 0.6 7.3 7 0 0 7 7 7 5 FG-GAP repeat DEAD_2 PF06733.15 EGG20082.1 - 3.1e-53 180.0 0.5 3.1e-53 180.0 0.5 1.9 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 EGG20082.1 - 8.1e-47 159.6 0.0 1.9e-46 158.4 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 EGG20082.1 - 9.2e-32 110.3 0.0 7.2e-28 97.6 0.0 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 EGG20082.1 - 5.6e-06 26.5 0.5 0.00029 20.9 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG20082.1 - 0.003 17.4 0.0 0.49 10.1 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGG20082.1 - 0.038 14.3 0.0 5.4 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain TMEMspv1-c74-12 PF11044.8 EGG20083.1 - 0.0078 16.2 0.3 0.12 12.4 0.0 2.7 2 0 0 2 2 2 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein DDE_Tnp_1_assoc PF13808.6 EGG20083.1 - 0.07 13.2 0.0 0.56 10.3 0.0 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-associated GEN1_C PF18380.1 EGG20083.1 - 0.73 10.8 8.3 0.16 12.9 4.5 1.9 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Sporozoite_P67 PF05642.11 EGG20083.1 - 2.9 5.9 6.7 5.6 4.9 6.7 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.11 EGG20083.1 - 4.6 5.7 17.0 0.0095 14.5 4.2 2.6 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 EGG20083.1 - 5.5 6.6 9.6 16 5.1 9.6 1.8 1 0 0 1 1 1 0 FAM176 family BUD22 PF09073.10 EGG20083.1 - 7.4 5.8 13.1 0.043 13.2 4.3 1.7 2 0 0 2 2 2 0 BUD22 tRNA_int_endo PF01974.17 EGG20084.1 - 8.2e-17 61.1 0.0 1.8e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain CDC45 PF02724.14 EGG20084.1 - 0.034 12.5 6.8 0.04 12.2 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Mem_trans PF03547.18 EGG20084.1 - 0.093 11.1 0.7 0.14 10.5 0.7 1.2 1 0 0 1 1 1 0 Membrane transport protein CAF1 PF04857.20 EGG20084.1 - 0.21 10.7 7.6 0.28 10.3 7.6 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease Presenilin PF01080.17 EGG20084.1 - 0.6 8.8 7.1 0.75 8.5 7.1 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EGG20085.1 - 1.3e-49 169.2 11.7 1.6e-49 169.0 11.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 EGG20086.1 - 7.2e-48 163.5 14.9 7.2e-48 163.5 14.9 1.3 2 0 0 2 2 2 1 ZIP Zinc transporter ASF1_hist_chap PF04729.13 EGG20087.1 - 7.8e-66 220.8 0.1 8.7e-66 220.6 0.1 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone NICE-3 PF07406.11 EGG20089.1 - 0.00085 19.4 0.1 0.00085 19.4 0.1 2.1 2 0 0 2 2 2 1 NICE-3 protein TPP1 PF10341.9 EGG20090.1 - 0.00023 21.1 0.2 0.0025 17.8 0.0 2.9 2 0 0 2 2 2 1 Shelterin complex subunit, TPP1/ACD Glycos_transf_1 PF00534.20 EGG20091.1 - 0.0038 16.8 0.2 0.21 11.1 0.0 2.7 1 1 2 3 3 3 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGG20091.1 - 0.17 12.3 0.0 0.77 10.2 0.0 2.3 1 1 0 1 1 1 0 Glycosyl transferases group 1 Ribosomal_L32p PF01783.23 EGG20092.1 - 3e-09 37.0 8.7 3.7e-09 36.7 7.9 1.6 1 1 1 2 2 2 1 Ribosomal L32p protein family DUF4410 PF14366.6 EGG20092.1 - 0.073 13.0 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) DUF2039 PF10217.9 EGG20092.1 - 0.077 13.3 1.6 0.081 13.3 0.5 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Hydant_A_N PF05378.13 EGG20093.1 - 0.12 12.1 1.3 0.2 11.3 1.3 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Ribosomal_S9 PF00380.19 EGG20093.1 - 0.2 12.2 0.2 0.42 11.1 0.2 1.6 1 0 0 1 1 1 0 Ribosomal protein S9/S16 DENN PF02141.21 EGG20095.1 - 1.3e-47 162.2 9.0 1.5e-37 129.4 0.9 3.8 3 0 0 3 3 3 2 DENN (AEX-3) domain LRR_8 PF13855.6 EGG20095.1 - 3e-18 65.3 16.8 2.9e-10 39.8 0.7 3.7 3 0 0 3 3 3 3 Leucine rich repeat DUF2340 PF10209.9 EGG20095.1 - 3.6e-17 62.9 3.2 6e-08 33.2 0.2 3.3 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2340) uDENN PF03456.18 EGG20095.1 - 6.5e-11 42.8 1.3 3.3e-10 40.6 1.3 2.4 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 EGG20095.1 - 3.1e-07 30.3 3.3 1.6e-06 28.0 3.3 2.4 1 0 0 1 1 1 1 dDENN domain LRR_4 PF12799.7 EGG20095.1 - 7.4e-07 29.4 30.1 0.0078 16.6 1.4 5.7 3 1 1 6 6 6 4 Leucine Rich repeats (2 copies) SPA PF08616.10 EGG20095.1 - 0.00021 21.2 1.9 0.0029 17.5 0.5 2.7 2 0 0 2 2 2 1 Stabilization of polarity axis LRR_9 PF14580.6 EGG20095.1 - 0.0056 16.2 0.5 0.0056 16.2 0.5 2.4 1 1 2 3 3 3 1 Leucine-rich repeat SKG6 PF08693.10 EGG20096.1 - 0.0041 16.5 2.0 0.0041 16.5 2.0 2.4 2 0 0 2 2 2 1 Transmembrane alpha-helix domain EGF_2 PF07974.13 EGG20096.1 - 0.016 15.5 12.7 0.048 14.0 12.7 1.8 1 0 0 1 1 1 0 EGF-like domain AMP-binding PF00501.28 EGG20097.1 - 1.1e-108 363.6 0.0 1.4e-108 363.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG20097.1 - 0.0079 17.2 0.0 0.022 15.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ThiF PF00899.21 EGG20098.1 - 6.4e-65 218.9 0.1 9.2e-65 218.4 0.1 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EGG20098.1 - 1.4e-23 82.8 0.4 2.2e-23 82.2 0.4 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.9 EGG20098.1 - 0.021 14.7 0.9 0.84 9.5 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 EGG20098.1 - 0.024 14.7 0.2 0.071 13.2 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 EGG20098.1 - 0.058 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Xin PF08043.12 EGG20098.1 - 0.13 11.9 0.9 0.31 10.7 0.9 1.6 1 0 0 1 1 1 0 Xin repeat Claudin_2 PF13903.6 EGG20099.1 - 3.1e-05 23.8 0.2 5.3e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Erf4 PF10256.9 EGG20099.1 - 0.00012 22.2 0.1 0.00046 20.3 0.1 2.0 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3267 PF11667.8 EGG20099.1 - 0.019 15.2 1.0 0.031 14.6 1.0 1.4 1 0 0 1 1 1 0 Putative zincin peptidase DUF2207 PF09972.9 EGG20099.1 - 0.049 12.4 0.6 0.068 11.9 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4448 PF14610.6 EGG20099.1 - 0.062 13.1 2.7 5 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) MS_channel PF00924.18 EGG20099.1 - 1.4 8.5 5.4 2.3 7.7 5.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel GN3L_Grn1 PF08701.11 EGG20100.1 - 4.7e-21 74.7 13.8 4.7e-21 74.7 13.8 3.9 3 1 0 4 4 4 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EGG20100.1 - 6.9e-16 58.4 6.5 1.1e-14 54.5 0.2 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG20100.1 - 4.8e-11 42.4 1.4 3.1e-08 33.3 0.2 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGG20100.1 - 1.3e-06 28.4 2.3 0.00024 21.0 0.9 3.1 2 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGG20100.1 - 0.021 15.2 0.0 0.021 15.2 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 EGG20100.1 - 0.6 10.7 0.0 0.6 10.7 0.0 3.2 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EGG20100.1 - 5.4 7.0 18.7 4 7.5 0.1 5.2 3 2 1 4 4 4 0 Dynamin family DLIC PF05783.11 EGG20101.1 - 0.0025 16.7 7.3 0.0025 16.7 7.3 2.1 2 1 1 3 3 3 1 Dynein light intermediate chain (DLIC) Dehydrin PF00257.19 EGG20101.1 - 0.012 16.2 4.3 0.012 16.2 4.3 3.8 3 1 0 4 4 4 0 Dehydrin Chalcone_3 PF16036.5 EGG20101.1 - 0.013 15.6 0.0 0.013 15.6 0.0 3.0 3 0 0 3 3 3 0 Chalcone isomerase-like Zip PF02535.22 EGG20101.1 - 2.3 7.3 5.4 4.5 6.4 5.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Sacchrp_dh_C PF16653.5 EGG20102.1 - 7e-81 272.2 0.0 9.8e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EGG20102.1 - 5.8e-22 78.3 0.0 1.1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGG20102.1 - 0.0031 17.4 0.0 0.011 15.6 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding HMG-CoA_red PF00368.18 EGG20103.1 - 2.7e-145 484.0 2.7 3.9e-145 483.5 2.7 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase DUF966 PF06136.13 EGG20103.1 - 0.57 9.8 9.1 0.86 9.3 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.9 EGG20103.1 - 1.2 7.6 9.7 1.6 7.2 9.7 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 EGG20103.1 - 3.3 7.2 11.1 4.5 6.7 11.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 EGG20103.1 - 5.5 5.9 9.7 8.4 5.3 9.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 tRNA-synt_2b PF00587.25 EGG20105.1 - 9.6e-39 133.2 0.1 1.6e-38 132.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGG20105.1 - 3.5e-17 62.6 5.2 8.5e-17 61.3 5.2 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain MCC-bdg_PDZ PF10506.9 EGG20105.1 - 0.12 12.4 0.2 0.3 11.1 0.2 1.7 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome bZIP_1 PF00170.21 EGG20105.1 - 0.16 12.1 1.1 1.4 9.1 0.2 2.4 2 0 0 2 2 2 0 bZIP transcription factor Cnn_1N PF07989.11 EGG20105.1 - 0.22 11.7 3.6 0.28 11.4 1.0 2.4 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 EGG20105.1 - 2.1 8.8 5.4 0.72 10.3 0.1 2.8 3 0 0 3 3 3 0 Cell division protein ZapB DivIC PF04977.15 EGG20105.1 - 9.3 6.1 9.7 7.2 6.5 3.4 2.8 1 1 1 2 2 2 0 Septum formation initiator PARP PF00644.20 EGG20107.1 - 1.1e-32 113.2 0.2 7.7e-31 107.2 0.2 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGG20107.1 - 4.8e-18 65.6 1.7 1.1e-17 64.4 1.7 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain BRCT_2 PF16589.5 EGG20107.1 - 4.5e-09 36.6 0.4 1.1e-08 35.3 0.4 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG20107.1 - 6.1e-09 36.1 0.5 2e-08 34.5 0.5 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ank_2 PF12796.7 EGG20107.1 - 3.3e-08 34.0 0.0 2.9e-07 31.0 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG20107.1 - 1.3e-07 31.8 0.3 3.1e-06 27.3 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) WGR PF05406.15 EGG20107.1 - 2e-07 31.0 0.0 5e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 WGR domain Ank_4 PF13637.6 EGG20107.1 - 4.8e-07 30.2 0.0 1.9e-06 28.3 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG20107.1 - 1.6e-05 24.9 0.1 0.00061 20.0 0.0 3.1 3 0 0 3 3 2 1 Ankyrin repeat Ank PF00023.30 EGG20107.1 - 0.0001 22.5 0.0 0.00055 20.3 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeat PTCB-BRCT PF12738.7 EGG20107.1 - 0.046 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 twin BRCT domain LIG3_BRCT PF16759.5 EGG20107.1 - 0.14 12.4 0.4 0.29 11.4 0.4 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain DUF4461 PF14688.6 EGG20108.1 - 7.9e-26 91.6 4.4 1.9e-25 90.4 0.2 3.4 4 1 0 4 4 4 1 Domain of unknown function (DUF4461) DUF4460 PF14687.6 EGG20108.1 - 9.6e-26 90.0 4.4 9.6e-26 90.0 4.4 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4460) Orthopox_A5L PF06193.11 EGG20108.1 - 0.13 11.7 3.9 0.32 10.4 3.9 1.6 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Gal4_dimer PF03902.13 EGG20108.1 - 1.8 8.8 10.1 25 5.1 5.7 3.7 2 1 0 2 2 2 0 Gal4-like dimerisation domain adh_short PF00106.25 EGG20110.1 - 1.4e-37 129.1 1.1 1.6e-37 128.8 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG20110.1 - 8e-28 97.6 0.2 1e-27 97.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG20110.1 - 9e-11 42.0 0.2 1.3e-10 41.5 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGG20110.1 - 7.7e-07 28.8 0.0 1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EGG20110.1 - 0.0011 18.6 0.3 0.056 13.0 0.3 2.1 2 0 0 2 2 2 1 NmrA-like family Eno-Rase_NADH_b PF12242.8 EGG20110.1 - 0.018 14.8 0.2 0.05 13.4 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 EGG20110.1 - 0.049 13.1 0.4 0.15 11.5 0.4 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TMEM151 PF14857.6 EGG20111.1 - 6.3e-16 58.3 6.0 9.1e-16 57.8 6.0 1.2 1 0 0 1 1 1 1 TMEM151 family TMEM151 PF14857.6 EGG20112.1 - 4e-17 62.3 2.5 5.1e-17 61.9 2.5 1.1 1 0 0 1 1 1 1 TMEM151 family Ank_2 PF12796.7 EGG20113.1 - 0.031 14.9 0.5 0.94 10.1 0.6 3.4 3 1 1 4 4 4 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG20113.1 - 2.6 8.9 6.9 19 6.2 0.3 5.6 6 0 0 6 6 6 0 Ankyrin repeat zf-C3H1 PF10650.9 EGG20114.1 - 3.6e-09 36.2 1.5 6.2e-09 35.4 1.5 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Peptidase_M13_N PF05649.13 EGG20115.1 - 0.00079 19.2 1.3 0.00091 19.0 1.3 1.0 1 0 0 1 1 1 1 Peptidase family M13 Complex1_LYR_2 PF13233.6 EGG20115.1 - 0.17 12.6 0.3 0.26 12.0 0.3 1.5 1 1 0 1 1 1 0 Complex1_LYR-like Kelch_1 PF01344.25 EGG20116.1 - 6.9e-31 105.6 13.6 1.9e-10 40.2 0.2 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EGG20116.1 - 4e-29 100.4 24.1 1.1e-07 31.7 0.2 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG20116.1 - 1.6e-28 98.2 16.8 3e-05 23.9 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EGG20116.1 - 3.1e-24 84.4 23.2 5.8e-07 29.6 0.4 6.5 3 2 3 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGG20116.1 - 1.3e-22 79.6 17.1 2.1e-06 27.9 0.0 7.1 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EGG20116.1 - 1.7e-22 78.4 19.2 2.9e-06 27.0 1.4 7.8 7 1 0 7 7 7 5 Kelch motif F-box PF00646.33 EGG20116.1 - 1.6e-06 27.8 0.1 3.4e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGG20116.1 - 4e-06 26.6 0.1 1e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like RAG2 PF03089.14 EGG20116.1 - 0.035 13.1 0.1 1 8.2 0.0 2.7 3 0 0 3 3 3 0 Recombination activating protein 2 WW PF00397.26 EGG20116.1 - 0.09 12.9 2.5 0.6 10.2 2.5 2.5 1 0 0 1 1 1 0 WW domain Pkinase PF00069.25 EGG20118.1 - 3e-73 246.4 0.0 4.8e-73 245.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20118.1 - 1.5e-37 129.3 0.0 3e-37 128.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 EGG20118.1 - 0.00065 19.4 0.2 0.0014 18.3 0.2 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGG20118.1 - 0.011 15.6 0.0 0.1 12.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG20118.1 - 0.049 13.0 0.1 0.074 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3439 PF11921.8 EGG20118.1 - 0.45 10.5 7.3 0.89 9.5 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FAM220 PF15487.6 EGG20118.1 - 0.78 9.3 10.7 1.7 8.2 10.7 1.5 1 0 0 1 1 1 0 FAM220 family IMUP PF15761.5 EGG20118.1 - 4.3 8.1 9.4 7.6 7.3 9.4 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein IATP PF04568.12 EGG20120.1 - 1.9e-06 28.2 0.9 1.9e-06 28.2 0.9 1.8 1 1 1 2 2 2 1 Mitochondrial ATPase inhibitor, IATP FlxA PF14282.6 EGG20120.1 - 0.02 14.8 2.2 0.02 14.8 2.2 2.1 1 1 1 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 EGG20120.1 - 0.028 14.6 7.8 0.036 14.3 7.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FapA PF03961.13 EGG20120.1 - 0.048 12.3 9.2 0.051 12.2 9.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A AOC_like PF18678.1 EGG20120.1 - 0.06 13.0 0.2 0.081 12.5 0.2 1.1 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain AKNA PF12443.8 EGG20120.1 - 0.11 13.2 6.7 0.38 11.4 6.7 1.9 1 1 0 1 1 1 0 AT-hook-containing transcription factor ADIP PF11559.8 EGG20120.1 - 0.18 11.9 11.2 0.22 11.6 11.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 EGG20120.1 - 0.25 10.2 13.0 0.3 9.9 13.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Med9 PF07544.13 EGG20120.1 - 0.32 11.1 9.7 0.86 9.7 9.3 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF724 PF05266.14 EGG20120.1 - 0.33 10.8 11.2 0.38 10.6 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Snf7 PF03357.21 EGG20120.1 - 0.37 10.4 14.7 0.42 10.2 2.9 2.1 2 0 0 2 2 2 0 Snf7 Fzo_mitofusin PF04799.13 EGG20120.1 - 0.69 9.4 6.6 1.2 8.6 6.6 1.4 1 1 0 1 1 1 0 fzo-like conserved region DUF4140 PF13600.6 EGG20120.1 - 0.94 10.0 8.5 42 4.7 8.5 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 EGG20120.1 - 2 8.4 8.9 3.5 7.7 8.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 EGG20120.1 - 8 6.3 15.6 0.069 12.9 2.2 2.5 1 1 1 2 2 2 0 Septum formation initiator eIF-1a PF01176.19 EGG20121.1 - 1.4e-09 37.6 0.1 3.6e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 DHHC PF01529.20 EGG20122.1 - 4.8e-09 36.4 31.8 6.7e-09 36.0 14.7 2.4 2 0 0 2 2 2 2 DHHC palmitoyltransferase FYVE PF01363.21 EGG20122.1 - 0.13 12.4 11.7 0.22 11.7 11.7 1.3 1 0 0 1 1 1 0 FYVE zinc finger 7tm_2 PF00002.24 EGG20123.1 - 4.8e-05 22.8 8.7 9e-05 21.9 8.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ras PF00071.22 EGG20125.1 - 1.6e-65 219.7 0.1 2e-65 219.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG20125.1 - 2.7e-35 121.2 0.0 4.6e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG20125.1 - 5.8e-15 55.2 0.1 7e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG20125.1 - 7.6e-06 25.6 0.1 3.9e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGG20125.1 - 3.9e-05 23.1 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG20125.1 - 8.9e-05 22.5 0.0 0.00032 20.8 0.0 1.8 1 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG20125.1 - 0.00049 20.1 0.2 0.24 11.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGG20125.1 - 0.0075 15.7 0.0 0.02 14.3 0.0 1.5 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit DUF3963 PF13124.6 EGG20125.1 - 0.0084 16.1 0.2 0.019 14.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3963) MCM PF00493.23 EGG20125.1 - 0.024 13.7 0.0 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 EGG20125.1 - 0.037 13.8 0.3 0.1 12.3 0.3 1.8 1 1 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG20125.1 - 0.07 13.5 0.0 0.095 13.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EGG20125.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DNA_ligase_A_M PF01068.21 EGG20126.1 - 8.4e-63 211.7 0.0 1.8e-62 210.6 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGG20126.1 - 4.2e-42 144.4 1.5 8.6e-42 143.4 0.0 2.2 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGG20126.1 - 5e-25 88.0 0.0 1.9e-24 86.1 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 EGG20126.1 - 0.011 15.7 0.1 0.39 10.8 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain RXLR PF16810.5 EGG20126.1 - 7 7.1 17.8 10 6.5 8.0 2.6 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity TSC22 PF01166.18 EGG20127.1 - 0.0094 16.2 1.2 0.0094 16.2 1.2 8.4 8 1 1 9 9 9 3 TSC-22/dip/bun family TPR_MLP1_2 PF07926.12 EGG20127.1 - 0.013 15.6 28.3 0.013 15.6 28.3 8.5 3 1 5 8 8 8 0 TPR/MLP1/MLP2-like protein EF-hand_7 PF13499.6 EGG20129.1 - 3.6e-14 53.0 3.9 3.8e-08 33.7 0.3 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EGG20129.1 - 2.1e-11 42.5 10.7 0.0065 15.9 1.0 4.5 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGG20129.1 - 1e-09 37.5 8.3 0.24 11.4 0.1 4.5 4 1 0 4 4 4 4 EF-hand domain Knl1_RWD_C PF18210.1 EGG20129.1 - 0.0058 17.1 0.2 0.013 15.9 0.1 1.6 2 0 0 2 2 2 1 Knl1 RWD C-terminal domain EF-hand_8 PF13833.6 EGG20129.1 - 0.012 15.5 5.3 0.61 10.0 1.0 3.5 3 1 1 4 4 4 0 EF-hand domain pair XFP_C PF09363.10 EGG20129.1 - 0.08 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 XFP C-terminal domain N6_N4_Mtase PF01555.18 EGG20130.1 - 0.02 14.6 0.1 0.02 14.6 0.1 3.3 2 1 1 3 3 3 0 DNA methylase DDE_Tnp_1_7 PF13843.6 EGG20131.1 - 3.2e-27 95.8 3.6 3.2e-27 95.8 3.6 3.1 2 1 0 2 2 2 1 Transposase IS4 RNA_pol_Rpb4 PF03874.16 EGG20131.1 - 8.3e-10 39.1 0.3 8.3e-10 39.1 0.3 4.0 3 1 1 4 4 4 1 RNA polymerase Rpb4 Apt1 PF10351.9 EGG20131.1 - 5.3e-06 25.6 5.6 5.3e-06 25.6 5.6 2.2 1 1 1 2 2 2 1 Golgi-body localisation protein domain PHD_2 PF13831.6 EGG20131.1 - 0.05 13.2 1.4 0.13 11.9 1.4 1.6 1 0 0 1 1 1 0 PHD-finger Pex14_N PF04695.13 EGG20131.1 - 0.058 14.1 20.4 0.17 12.5 4.6 2.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BUD22 PF09073.10 EGG20131.1 - 0.061 12.7 31.9 0.094 12.0 31.9 1.2 1 0 0 1 1 1 0 BUD22 PTEN_C2 PF10409.9 EGG20132.1 - 7.5e-22 77.5 0.1 7.5e-22 77.5 0.1 2.3 2 1 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein PH PF00169.29 EGG20132.1 - 1.6e-21 76.7 0.0 5.9e-21 75.0 0.0 2.0 1 0 0 1 1 1 1 PH domain Y_phosphatase PF00102.27 EGG20132.1 - 2.8e-07 30.3 1.0 3e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PH_11 PF15413.6 EGG20132.1 - 6.3e-06 26.6 1.4 6.3e-06 26.6 1.4 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain DSPc PF00782.20 EGG20132.1 - 1.5e-05 24.8 7.6 1.7e-05 24.6 0.0 2.8 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain PH_8 PF15409.6 EGG20132.1 - 7.2e-05 23.0 0.1 0.00023 21.4 0.1 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain Y_phosphatase3 PF13350.6 EGG20132.1 - 0.00014 21.9 0.0 0.00036 20.6 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 EGG20132.1 - 0.0013 18.4 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 EGG20132.1 - 0.0034 17.5 0.2 0.016 15.3 0.0 2.2 2 0 0 2 2 2 1 Inositol hexakisphosphate PH_3 PF14593.6 EGG20132.1 - 0.011 15.8 1.0 0.025 14.7 0.0 2.1 3 0 0 3 3 3 0 PH domain Menin PF05053.13 EGG20132.1 - 2.1 6.6 8.4 4 5.7 8.4 1.4 1 0 0 1 1 1 0 Menin APG5 PF04106.12 EGG20133.1 - 5.2e-54 183.3 0.0 6.5e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Pkinase PF00069.25 EGG20134.1 - 5.4e-77 258.7 0.0 2.1e-76 256.8 0.0 2.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20134.1 - 1.1e-31 110.1 0.0 2.4e-31 109.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGG20134.1 - 2.5e-13 50.1 0.1 8.2e-13 48.5 0.1 2.0 1 0 0 1 1 1 1 FHA domain BUD22 PF09073.10 EGG20134.1 - 0.00071 19.0 20.2 0.00071 19.0 20.2 1.6 2 0 0 2 2 2 1 BUD22 Yop-YscD_cpl PF16697.5 EGG20134.1 - 0.001 19.3 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EGG20134.1 - 0.015 14.7 0.0 0.049 13.0 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Isy1 PF06246.12 EGG20134.1 - 5.5 6.5 32.2 0.012 15.1 3.1 2.3 1 1 1 2 2 2 0 Isy1-like splicing family TAF4 PF05236.14 EGG20135.1 - 4.8e-30 105.3 14.6 4.8e-30 105.3 14.6 3.7 3 1 1 4 4 4 1 Transcription initiation factor TFIID component TAF4 family AvrM_N PF18247.1 EGG20135.1 - 0.0015 18.4 1.4 0.003 17.5 0.0 2.2 2 0 0 2 2 2 1 Flax-rust effector AvrM N-terminal domain TFIID_30kDa PF03540.13 EGG20135.1 - 0.081 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit LXG PF04740.12 EGG20136.1 - 0.0016 18.2 2.3 0.0016 18.2 2.3 3.3 1 1 2 3 3 3 1 LXG domain of WXG superfamily PI_PP_I PF18363.1 EGG20136.1 - 0.018 15.2 4.1 1.6 8.9 0.1 3.5 2 1 3 5 5 5 0 Phosphoinositide phosphatase insertion domain VIT PF08487.10 EGG20136.1 - 0.24 11.6 5.0 1.3 9.2 0.2 3.4 3 0 0 3 3 3 0 Vault protein inter-alpha-trypsin domain DASH_Dad3 PF08656.10 EGG20136.1 - 0.41 10.8 10.6 0.75 9.9 0.8 3.6 3 1 0 3 3 3 0 DASH complex subunit Dad3 YojJ PF10372.9 EGG20136.1 - 3 8.0 9.2 2.9 8.0 2.6 2.9 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF2935 PF11155.8 EGG20136.1 - 3.2 8.1 11.9 11 6.3 4.6 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) HAD_2 PF13419.6 EGG20137.1 - 1.9e-09 37.8 0.0 0.00045 20.4 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGG20137.1 - 0.00047 20.2 0.0 0.00082 19.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGG20137.1 - 0.01 16.1 0.0 0.57 10.4 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 EGG20137.1 - 0.017 14.9 1.2 0.093 12.4 1.2 2.0 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase PIF1 PF05970.14 EGG20138.1 - 1.6e-48 165.7 5.2 5.8e-47 160.6 2.4 3.4 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 EGG20138.1 - 1.7e-17 63.8 0.0 1.8e-16 60.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain Cauli_VI PF01693.16 EGG20138.1 - 7.7e-15 54.9 0.8 6.3e-14 52.0 0.1 2.5 2 0 0 2 2 2 1 Caulimovirus viroplasmin AAA_19 PF13245.6 EGG20138.1 - 5.3e-14 52.8 0.0 2.1e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGG20138.1 - 0.00012 22.3 0.0 0.00044 20.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF572 PF04502.13 EGG20139.1 - 2.3e-75 254.3 20.7 5e-75 253.2 20.7 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF572) ATP-synt_ab PF00006.25 EGG20139.1 - 6.4e-68 228.6 0.0 9.8e-68 228.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGG20139.1 - 7e-10 39.3 0.2 1.6e-09 38.1 0.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3752 PF12572.8 EGG20139.1 - 0.069 13.7 7.6 0.17 12.4 7.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DUF2206 PF09971.9 EGG20139.1 - 0.2 10.3 0.8 0.4 9.4 0.8 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) RNA_pol_N PF01194.17 EGG20139.1 - 1.3 9.4 2.8 2.6 8.4 0.2 2.8 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit WD40 PF00400.32 EGG20140.1 - 4.9e-45 150.6 30.7 0.00011 22.9 0.5 11.9 12 0 0 12 12 12 9 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGG20140.1 - 0.00022 20.3 8.3 0.029 13.3 0.0 4.9 4 2 0 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 EGG20140.1 - 0.027 14.5 3.7 29 4.8 0.0 5.8 8 0 0 8 8 8 0 Ciliary BBSome complex subunit 2, middle region Copine PF07002.16 EGG20141.1 - 5.6e-67 225.4 0.0 8e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGG20141.1 - 8.2e-18 64.6 0.1 1.3e-08 35.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGG20141.1 - 2.1e-05 24.7 0.0 6.8e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 vWA found in TerF C terminus COesterase PF00135.28 EGG20142.1 - 1.7e-118 396.7 0.0 6.7e-118 394.8 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG20142.1 - 2.5e-11 43.8 0.1 5.2e-11 42.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG20142.1 - 0.00047 19.7 0.0 0.00095 18.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGG20142.1 - 0.011 16.3 0.5 0.019 15.6 0.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Epimerase PF01370.21 EGG20143.1 - 1.4e-12 47.6 0.0 1.2e-11 44.6 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1731 PF08338.11 EGG20143.1 - 1.8e-09 37.3 0.0 3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) RmlD_sub_bind PF04321.17 EGG20143.1 - 8.3e-07 28.4 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGG20143.1 - 5.7e-06 25.9 0.0 0.0002 20.9 0.0 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EGG20143.1 - 3.2e-05 23.6 0.0 4.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EGG20143.1 - 0.0052 15.8 0.0 0.0072 15.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGG20143.1 - 0.024 14.6 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_4 PF07993.12 EGG20143.1 - 0.03 13.5 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein KR PF08659.10 EGG20143.1 - 0.063 13.2 0.0 0.53 10.2 0.0 2.0 1 1 1 2 2 2 0 KR domain adh_short PF00106.25 EGG20143.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EGG20143.1 - 0.16 11.1 0.0 3.3 6.7 0.1 2.2 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein SET PF00856.28 EGG20144.1 - 2e-10 41.3 1.0 1.1e-09 38.9 1.0 2.1 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGG20144.1 - 0.00017 21.6 9.7 0.00017 21.6 9.7 2.7 3 0 0 3 3 3 1 MYND finger CAF1A PF12253.8 EGG20145.1 - 7.6e-23 80.5 8.8 7.6e-23 80.5 8.8 7.0 3 2 1 4 4 4 1 Chromatin assembly factor 1 subunit A Caldesmon PF02029.15 EGG20145.1 - 0.0026 16.6 74.2 0.0026 16.6 74.2 3.1 2 1 1 3 3 3 1 Caldesmon SGT1 PF07093.11 EGG20146.1 - 1.4e-118 396.9 40.1 9.9e-118 394.1 40.1 1.9 1 1 0 1 1 1 1 SGT1 protein PTPA PF03095.15 EGG20146.1 - 0.001 18.6 3.8 0.002 17.7 3.8 1.5 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Methyltranf_PUA PF13636.6 EGG20146.1 - 0.097 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF TFIIA PF03153.13 EGG20146.1 - 1 9.3 44.8 0.018 15.0 31.1 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Methyltransf_23 PF13489.6 EGG20147.1 - 3.7e-13 49.6 0.1 6.9e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG20147.1 - 5e-11 43.1 0.0 1.9e-10 41.3 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG20147.1 - 2.2e-09 38.0 6.3 1.4e-07 32.1 6.3 3.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG20147.1 - 1.1e-08 35.0 0.0 5.1e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG20147.1 - 3.5e-08 34.0 0.0 1.2e-07 32.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF3340 PF11818.8 EGG20147.1 - 0.48 10.6 0.1 0.48 10.6 0.1 2.9 2 1 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) DUF4551 PF15087.6 EGG20147.1 - 2.5 6.9 11.6 0.067 12.0 4.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4551) NUDIX PF00293.28 EGG20148.1 - 3.1e-09 37.0 0.0 6.9e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain Peptidase_S49_N PF08496.10 EGG20148.1 - 1.6 8.8 4.4 0.45 10.6 0.5 2.1 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Arm PF00514.23 EGG20149.1 - 1.4e-64 212.4 2.4 8.4e-12 44.7 0.0 10.0 10 0 0 10 10 10 7 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGG20149.1 - 3.1e-15 56.3 0.5 8.5e-10 38.9 0.1 6.0 6 1 0 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 EGG20149.1 - 2.3e-14 53.5 1.6 9.4e-08 32.3 0.0 6.2 2 1 4 6 6 6 2 HEAT repeats HEAT PF02985.22 EGG20149.1 - 3.9e-08 32.9 0.1 0.0012 18.9 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat RICTOR_V PF14668.6 EGG20149.1 - 4.3e-05 23.7 5.4 1.4 9.2 0.0 6.0 5 1 2 7 7 7 2 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 EGG20149.1 - 7.2e-05 22.5 0.3 0.46 10.0 0.0 4.2 4 1 1 5 5 5 2 Nucleolar pre-ribosomal-associated protein 1 V-ATPase_H_C PF11698.8 EGG20149.1 - 0.00015 21.8 0.1 1.9 8.6 0.0 3.8 4 0 0 4 4 4 2 V-ATPase subunit H HEAT_PBS PF03130.16 EGG20149.1 - 0.0034 17.9 2.5 2.5 9.0 0.0 5.0 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat Rcd1 PF04078.13 EGG20149.1 - 0.0052 16.1 0.6 1.8 7.8 0.0 3.3 4 0 0 4 4 4 1 Cell differentiation family, Rcd1-like CTNNBL PF08216.11 EGG20149.1 - 0.026 14.7 0.5 26 5.0 0.0 3.6 3 1 0 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear IBB PF01749.20 EGG20149.1 - 0.051 14.0 0.3 0.19 12.2 0.1 2.2 2 0 0 2 2 2 0 Importin beta binding domain YukD PF08817.10 EGG20149.1 - 0.11 13.2 0.1 8.1 7.2 0.0 3.4 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD UCH PF00443.29 EGG20150.1 - 3.2e-46 157.9 11.0 3.2e-46 157.9 11.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG20150.1 - 2.2e-16 60.4 22.5 2.2e-16 60.4 22.5 3.0 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGG20150.1 - 5.8e-15 55.4 15.2 5.8e-15 55.4 15.2 3.5 2 1 1 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Corazonin PF17308.2 EGG20150.1 - 0.038 14.4 25.0 0.57 10.6 1.2 4.6 4 0 0 4 4 4 0 Pro-corazonin Met_synt_B12 PF02965.17 EGG20151.1 - 1.9e-119 398.1 0.0 3.2e-119 397.4 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 EGG20151.1 - 2.7e-74 250.3 0.0 6.8e-74 249.1 0.0 1.7 2 0 0 2 2 2 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 EGG20151.1 - 3.7e-40 138.1 0.9 2.5e-29 102.7 0.1 3.0 2 1 1 3 3 3 2 Pterin binding enzyme B12-binding_2 PF02607.17 EGG20151.1 - 7.6e-25 87.2 0.2 3.7e-24 85.0 0.1 2.4 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 EGG20151.1 - 3.5e-18 65.8 1.0 1.4e-17 63.9 0.4 2.3 2 0 0 2 2 2 1 B12 binding domain OKR_DC_1_N PF03709.15 EGG20151.1 - 0.11 12.7 0.2 6.5 7.1 0.1 2.8 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain Inositol_P PF00459.25 EGG20152.1 - 2.5e-68 230.5 0.1 3.2e-68 230.2 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF4054 PF13262.6 EGG20152.1 - 0.028 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Actin PF00022.19 EGG20153.1 - 6.2e-99 331.4 0.0 1.3e-98 330.3 0.0 1.5 1 1 0 1 1 1 1 Actin Sulf_transp PF04143.14 EGG20154.1 - 4.1e-59 200.7 20.2 5.1e-59 200.4 20.2 1.1 1 0 0 1 1 1 1 Sulphur transport 2OG-FeII_Oxy_2 PF13532.6 EGG20155.1 - 1.4e-25 90.6 0.1 1.4e-25 90.6 0.1 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ThiS PF02597.20 EGG20155.1 - 0.2 12.3 3.8 5 7.8 5.7 2.3 2 0 0 2 2 2 0 ThiS family DUF445 PF04286.12 EGG20155.1 - 1.3 8.8 16.0 2 8.1 16.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) LMBR1 PF04791.16 EGG20155.1 - 8.2 5.2 5.9 11 4.8 5.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 EGG20155.1 - 9.4 4.9 7.9 11 4.7 7.9 1.1 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 EGG20155.1 - 9.6 6.5 24.1 20 5.5 24.1 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Homoserine_dh PF00742.19 EGG20157.1 - 4.3e-50 170.0 0.1 1.3e-49 168.4 0.1 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase AA_kinase PF00696.28 EGG20157.1 - 1e-36 126.8 0.0 1.9e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family NAD_binding_3 PF03447.16 EGG20157.1 - 1.3e-16 61.3 0.0 3.4e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT_7 PF13840.6 EGG20157.1 - 1.1e-11 44.4 3.9 5.6e-09 35.7 0.4 3.0 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EGG20157.1 - 1.5e-10 40.6 0.4 3.5e-08 33.1 0.1 2.8 2 0 0 2 2 2 1 ACT domain GFO_IDH_MocA PF01408.22 EGG20157.1 - 0.024 15.5 0.0 0.097 13.5 0.0 2.2 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 EGG20157.1 - 0.093 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PCMT PF01135.19 EGG20159.1 - 9.1e-74 247.7 0.0 1.3e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EGG20159.1 - 8.7e-06 26.4 0.0 1.7e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG20159.1 - 8.8e-06 25.6 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EGG20159.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.12 EGG20159.1 - 0.0016 19.1 0.0 0.0042 17.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG20159.1 - 0.0025 17.7 0.0 0.0064 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG20159.1 - 0.0027 17.1 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EGG20159.1 - 0.0029 17.6 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG20159.1 - 0.0039 16.7 0.0 0.0085 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EGG20159.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGG20159.1 - 0.024 14.1 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EGG20159.1 - 0.035 14.2 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 EGG20159.1 - 0.093 13.8 0.0 0.26 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 EGG20159.1 - 0.14 11.3 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 Fibrillarin Ras PF00071.22 EGG20160.1 - 2.6e-49 166.9 0.0 3.1e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG20160.1 - 1.3e-22 80.3 0.0 1.9e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG20160.1 - 4.9e-07 29.4 0.0 6.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family p450 PF00067.22 EGG20161.1 - 4.8e-173 576.2 0.0 2.5e-86 290.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 EGG20162.1 - 2.2e-95 320.1 0.0 2.4e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nudix_hydro PF18290.1 EGG20163.1 - 1.1e-27 95.8 0.0 2.2e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 EGG20163.1 - 1.8e-21 76.6 0.0 3.4e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain V-set_2 PF15910.5 EGG20163.1 - 0.2 11.8 2.9 0.58 10.3 2.8 1.8 2 0 0 2 2 2 0 ICOS V-set domain zf-CCHC PF00098.23 EGG20164.1 - 0.00059 19.8 1.2 0.0011 19.0 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGG20164.1 - 0.097 12.4 1.3 0.21 11.4 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle RPAP2_Rtr1 PF04181.13 EGG20165.1 - 1e-21 77.0 0.7 1e-21 77.0 0.7 1.8 2 0 0 2 2 2 1 Rtr1/RPAP2 family TFIIB PF00382.19 EGG20166.1 - 2e-25 88.6 0.0 6.2e-15 55.0 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EGG20166.1 - 7.5e-10 39.1 10.3 7.5e-10 39.1 10.3 5.6 3 1 1 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EGG20166.1 - 0.00073 19.0 2.7 0.0037 16.7 2.7 2.3 1 0 0 1 1 1 1 TFIIB zinc-binding Ribosomal_L32e PF01655.18 EGG20167.1 - 3.7e-45 152.8 0.2 4.4e-45 152.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 YEATS PF03366.16 EGG20168.1 - 5.5e-27 93.6 1.6 1.1e-26 92.6 0.3 2.2 2 0 0 2 2 2 1 YEATS family Atrophin-1 PF03154.15 EGG20168.1 - 0.00028 19.3 6.5 0.00028 19.3 6.5 5.1 5 1 0 5 5 5 2 Atrophin-1 family SSP160 PF06933.11 EGG20169.1 - 0.0028 15.9 5.5 0.0028 15.9 5.5 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF4064 PF13273.6 EGG20169.1 - 0.032 14.5 3.3 0.039 14.2 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) MGC-24 PF05283.11 EGG20169.1 - 0.22 12.0 5.5 0.25 11.8 5.5 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4148 PF13663.6 EGG20169.1 - 0.51 10.6 7.4 1.3 9.3 7.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) Exo_endo_phos PF03372.23 EGG20171.1 - 7.6e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3439 PF11921.8 EGG20171.1 - 0.38 10.7 4.7 0.72 9.8 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ashwin PF15323.6 EGG20171.1 - 6.2 6.8 14.6 8.7 6.3 14.6 1.2 1 0 0 1 1 1 0 Developmental protein Exo_endo_phos PF03372.23 EGG20172.1 - 0.0055 16.3 0.0 0.0074 15.8 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FNIP PF05725.12 EGG20173.1 - 2.3e-36 123.7 27.1 3.8e-11 43.0 0.5 7.3 5 3 3 8 8 8 8 FNIP Repeat GATA PF00320.27 EGG20174.1 - 6.3e-09 35.3 3.6 1.4e-08 34.1 3.6 1.7 1 0 0 1 1 1 1 GATA zinc finger GATA PF00320.27 EGG20175.1 - 8.1e-12 44.6 3.8 1.2e-11 43.9 3.8 1.3 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EGG20175.1 - 0.015 14.8 1.6 0.031 13.8 1.6 1.5 1 1 0 1 1 1 0 TFIIB zinc-binding zf-RRN7 PF11781.8 EGG20175.1 - 0.12 12.1 0.8 0.2 11.4 0.8 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 AT_hook PF02178.19 EGG20175.1 - 0.14 12.1 2.0 0.39 10.7 2.0 1.8 1 0 0 1 1 1 0 AT hook motif G8 PF10162.9 EGG20176.1 - 0.023 14.8 6.1 0.034 14.2 0.1 3.6 2 1 2 4 4 4 0 G8 domain Man-6-P_recep PF02157.15 EGG20176.1 - 0.072 12.2 0.4 0.12 11.4 0.4 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate receptor PRELI PF04707.14 EGG20176.1 - 1.1 9.0 5.4 0.24 11.2 1.2 2.0 2 0 0 2 2 2 0 PRELI-like family GATA PF00320.27 EGG20177.1 - 7.2e-10 38.3 3.8 2.1e-09 36.8 3.8 1.9 1 0 0 1 1 1 1 GATA zinc finger zf-like PF04071.12 EGG20177.1 - 0.25 11.3 0.8 0.63 10.0 0.8 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain RRM_1 PF00076.22 EGG20178.1 - 3e-22 78.2 5.2 4.2e-12 45.7 0.2 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG20178.1 - 0.057 13.4 0.6 0.38 10.8 0.1 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Hep_59 PF07052.11 EGG20179.1 - 1.3e-22 80.5 11.6 1.3e-22 80.5 11.6 4.1 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF4871 PF16167.5 EGG20179.1 - 0.085 12.9 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4871) DEAD PF00270.29 EGG20180.1 - 7.3e-43 146.4 1.4 8.6e-43 146.1 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG20180.1 - 1.2e-22 80.3 0.0 1.4e-21 76.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGG20180.1 - 2.8e-18 65.9 0.0 6.2e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) GATA PF00320.27 EGG20180.1 - 4.7e-10 38.9 4.5 1.1e-09 37.8 4.5 1.7 1 0 0 1 1 1 1 GATA zinc finger AAA_22 PF13401.6 EGG20180.1 - 0.00081 19.7 0.0 0.0042 17.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain NAM-associated PF14303.6 EGG20180.1 - 0.45 11.2 0.0 0.45 11.2 0.0 6.9 4 3 3 7 7 7 0 No apical meristem-associated C-terminal domain VSP PF03302.13 EGG20181.1 - 0.052 12.4 0.2 0.085 11.7 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein FtsK_SpoIIIE_N PF12538.8 EGG20181.1 - 0.068 13.4 0.1 0.37 11.0 0.1 2.3 1 0 0 1 1 1 0 DNA transporter TIG PF01833.24 EGG20182.1 - 2.1e-22 79.0 45.4 4.4e-06 26.7 2.7 7.0 6 1 0 6 6 6 5 IPT/TIG domain Rad51 PF08423.11 EGG20183.1 - 5.6e-42 143.8 0.0 1.2e-41 142.7 0.0 1.5 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EGG20183.1 - 7.5e-11 42.0 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EGG20183.1 - 2.9e-08 33.4 0.2 5e-08 32.6 0.2 1.5 1 1 0 1 1 1 1 KaiC RecA PF00154.21 EGG20183.1 - 4.1e-07 29.8 1.0 0.00054 19.5 0.1 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein DnaB_C PF03796.15 EGG20183.1 - 1.3e-06 27.9 0.1 2.4e-06 27.1 0.1 1.4 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 EGG20183.1 - 7.8e-05 22.5 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG20183.1 - 0.00097 19.7 0.0 0.0024 18.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG20183.1 - 0.02 15.0 0.0 0.054 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGG20183.1 - 0.052 13.3 0.1 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 EGG20183.1 - 0.12 12.8 0.1 0.7 10.3 0.2 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PAXNEB PF05625.11 EGG20183.1 - 0.15 11.1 0.1 15 4.6 0.1 2.1 2 0 0 2 2 2 0 PAXNEB protein SMC_Nse1 PF07574.13 EGG20184.1 - 2.8e-23 82.8 0.6 9.6e-17 61.5 0.2 2.1 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING_2 PF13639.6 EGG20184.1 - 0.0014 18.9 16.2 0.0024 18.2 16.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGG20184.1 - 0.07 13.4 13.2 0.15 12.4 13.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Imm39 PF15568.6 EGG20184.1 - 0.15 12.2 0.1 0.38 10.9 0.1 1.7 1 1 0 1 1 1 0 Immunity protein 39 zf-RING_9 PF13901.6 EGG20184.1 - 0.37 10.7 16.1 0.42 10.6 12.3 2.1 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon zf-RING-like PF08746.11 EGG20184.1 - 0.82 10.0 14.3 1.6 9.1 14.3 1.5 1 1 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 EGG20184.1 - 3.2 7.4 12.0 5.4 6.7 12.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Synaptobrevin PF00957.21 EGG20185.1 - 4.9e-28 96.8 6.5 5.3e-28 96.6 6.5 1.0 1 0 0 1 1 1 1 Synaptobrevin LMBR1 PF04791.16 EGG20185.1 - 0.0019 17.2 1.2 0.0019 17.2 1.2 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein RIFIN PF02009.16 EGG20185.1 - 0.0024 17.8 3.6 0.0025 17.8 3.6 1.0 1 0 0 1 1 1 1 Rifin DUF2721 PF11026.8 EGG20185.1 - 0.0065 16.3 0.1 0.0075 16.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Orf78 PF06024.12 EGG20185.1 - 0.0066 16.7 1.1 0.0079 16.5 1.1 1.2 1 0 0 1 1 1 1 Orf78 (ac78) DUF4199 PF13858.6 EGG20185.1 - 0.0074 16.7 0.7 0.0083 16.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) UPF0258 PF06789.12 EGG20185.1 - 0.0089 16.2 6.2 0.011 15.9 6.2 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0258) TMEM154 PF15102.6 EGG20185.1 - 0.011 15.7 1.1 0.012 15.5 1.1 1.1 1 0 0 1 1 1 0 TMEM154 protein family Ferlin_C PF16165.5 EGG20185.1 - 0.015 15.3 0.3 0.017 15.1 0.3 1.2 1 0 0 1 1 1 0 Ferlin C-terminus EVI2A PF05399.11 EGG20185.1 - 0.021 14.4 0.7 0.022 14.3 0.7 1.0 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) LRRC37AB_C PF14914.6 EGG20185.1 - 0.035 14.0 2.3 0.041 13.8 2.3 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain MCU PF04678.13 EGG20185.1 - 0.085 12.9 0.5 0.093 12.8 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF2207 PF09972.9 EGG20185.1 - 0.095 11.4 0.1 0.094 11.5 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NPV_P10 PF05531.12 EGG20185.1 - 0.097 13.2 3.0 0.36 11.3 3.0 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CAF1C_H4-bd PF12265.8 EGG20186.1 - 3.4e-19 68.9 1.3 1.5e-18 66.8 0.2 2.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGG20186.1 - 3.1e-12 46.8 23.0 6.6e-06 26.8 0.2 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG20186.1 - 1.4e-07 31.7 0.5 0.016 15.5 0.1 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG20186.1 - 1.8e-05 24.7 0.7 9.8e-05 22.3 0.7 2.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A TIG PF01833.24 EGG20187.1 - 1.4e-15 57.1 45.1 3.3e-05 23.9 3.7 7.3 6 1 2 8 8 8 6 IPT/TIG domain DUF4448 PF14610.6 EGG20187.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 EGG20187.1 - 0.84 9.1 3.8 2.4 7.7 3.8 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FGGY_C PF02782.16 EGG20188.1 - 5.7e-64 215.5 0.6 1.2e-63 214.5 0.6 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGG20188.1 - 1.3e-62 211.5 0.1 5.6e-61 206.2 0.1 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Porphobil_deam PF01379.20 EGG20189.1 - 5e-78 261.3 0.0 6.1e-78 261.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EGG20189.1 - 3.9e-20 72.0 0.2 6.9e-20 71.2 0.2 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain RhoGAP PF00620.27 EGG20190.1 - 3.2e-36 124.4 0.0 7.1e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain C2 PF00168.30 EGG20190.1 - 2.4e-22 79.2 0.0 4.8e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain PH PF00169.29 EGG20190.1 - 2.6e-10 40.8 1.2 2e-09 37.9 0.1 2.6 3 0 0 3 3 3 1 PH domain PH_3 PF14593.6 EGG20190.1 - 3.4e-08 33.5 0.3 1.4e-06 28.3 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 EGG20190.1 - 0.027 14.8 0.1 0.19 12.1 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.6 EGG20190.1 - 0.068 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain DUF2857 PF11198.8 EGG20190.1 - 0.095 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) Pkinase PF00069.25 EGG20191.1 - 1.6e-42 145.7 0.1 1.1e-41 142.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20191.1 - 1.2e-28 100.1 0.1 3.3e-28 98.7 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 EGG20191.1 - 0.0025 17.5 0.3 0.74 9.4 0.0 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 2OG-FeII_Oxy_3 PF13640.6 EGG20192.1 - 1.2e-12 48.6 0.1 3e-12 47.3 0.1 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 EGG20192.1 - 3e-05 23.3 0.0 3.5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Poxvirus C4/C10 protein bZIP_1 PF00170.21 EGG20193.1 - 1.6e-08 34.5 7.2 1.6e-08 34.5 7.2 2.6 2 1 1 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 EGG20193.1 - 0.002 18.2 4.9 0.002 18.2 4.9 3.2 2 1 1 3 3 3 2 Basic region leucine zipper SOG2 PF10428.9 EGG20193.1 - 0.19 10.9 21.7 0.23 10.6 21.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TMF_DNA_bd PF12329.8 EGG20193.1 - 1.5 8.9 17.5 0.036 14.1 7.7 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_Maf PF03131.17 EGG20193.1 - 3.1 8.4 15.6 0.086 13.4 3.2 2.8 2 1 1 3 3 3 0 bZIP Maf transcription factor Suf PF05843.14 EGG20193.1 - 4.8 7.1 13.4 3.6 7.5 11.3 1.7 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) DLH PF01738.18 EGG20194.1 - 2e-29 102.7 0.0 2.4e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EGG20194.1 - 0.002 17.8 0.1 0.0033 17.1 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG20194.1 - 0.011 15.0 0.1 0.11 11.8 0.0 2.3 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG20194.1 - 0.016 15.8 0.6 0.039 14.5 0.5 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2048 PF09752.9 EGG20194.1 - 0.021 13.9 0.1 0.04 13.0 0.1 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 SAT PF16073.5 EGG20194.1 - 0.021 14.5 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis BAAT_C PF08840.11 EGG20194.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EGG20194.1 - 0.12 11.9 1.4 2.4 7.6 0.3 2.3 3 0 0 3 3 3 0 Prolyl oligopeptidase family Chlorophyllase PF07224.11 EGG20194.1 - 0.12 11.3 0.1 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase RRM_1 PF00076.22 EGG20195.1 - 6.2e-55 182.9 0.7 5.6e-20 70.9 0.2 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG20195.1 - 7.9e-09 35.2 0.1 0.24 11.0 0.0 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EGG20195.1 - 6.8e-08 32.7 0.2 0.0025 18.0 0.0 3.3 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_7 PF16367.5 EGG20195.1 - 9.9e-07 28.8 0.5 0.14 12.3 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 EGG20195.1 - 0.00034 20.6 0.0 2.5 8.2 0.0 3.7 3 1 0 3 3 3 1 RNA binding domain RRM_3 PF08777.11 EGG20195.1 - 0.0011 18.9 0.0 0.094 12.8 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif PHM7_cyt PF14703.6 EGG20195.1 - 0.0017 18.6 4.4 0.33 11.2 0.1 4.4 4 1 1 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 EGG20195.1 - 0.0041 16.9 0.0 0.89 9.5 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGG20195.1 - 0.097 12.7 0.0 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif C2 PF00168.30 EGG20197.1 - 6.3e-20 71.4 0.5 1.1e-19 70.6 0.5 1.5 1 0 0 1 1 1 1 C2 domain IBR PF01485.21 EGG20197.1 - 7.3e-10 38.9 5.3 7.3e-10 38.9 5.3 7.2 4 3 0 4 4 4 1 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EGG20197.1 - 1.9e-06 28.1 6.3 1.9e-06 28.1 6.3 6.5 5 3 0 5 5 5 2 Ring finger domain zf-RING_5 PF14634.6 EGG20197.1 - 3.2e-05 23.8 5.3 3.2e-05 23.8 5.3 7.3 6 3 1 7 7 7 2 zinc-RING finger domain zf-RING_11 PF17123.5 EGG20197.1 - 0.00014 21.5 4.8 0.00014 21.5 4.8 4.2 4 0 0 4 4 4 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGG20197.1 - 0.00018 21.4 1.5 0.00018 21.4 1.5 7.3 9 0 0 9 9 9 2 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG20197.1 - 0.00063 19.6 2.5 0.00063 19.6 2.5 7.1 7 3 1 8 8 8 2 Zinc finger, C3HC4 type (RING finger) PQQ_2 PF13360.6 EGG20199.1 - 0.032 13.8 0.0 0.076 12.6 0.0 1.7 1 0 0 1 1 1 0 PQQ-like domain Laminin_EGF PF00053.24 EGG20199.1 - 3 8.1 25.1 62 3.9 25.1 2.6 1 1 0 1 1 1 0 Laminin EGF domain Ribosomal_L13e PF01294.18 EGG20200.1 - 4.9e-64 215.5 5.4 6.3e-64 215.1 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e RNA_pol_N PF01194.17 EGG20201.1 - 4.4e-33 113.4 0.4 5.2e-33 113.1 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Corona_5a PF06336.11 EGG20201.1 - 0.0059 16.6 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 Coronavirus 5a protein Chordopox_RPO7 PF05864.12 EGG20201.1 - 0.0087 16.3 0.3 0.013 15.7 0.3 1.3 1 1 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Ocnus PF05005.15 EGG20202.1 - 0.013 15.6 0.2 0.025 14.7 0.2 1.4 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) DUF4602 PF15375.6 EGG20202.1 - 0.72 10.2 10.8 1.6 9.1 10.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4602) Lectin_leg-like PF03388.13 EGG20203.1 - 2e-54 184.4 0.0 5.6e-54 182.9 0.0 1.8 1 0 0 1 1 1 1 Legume-like lectin family MMPL PF03176.15 EGG20203.1 - 3.9 6.3 12.3 5.2 5.9 11.5 1.6 1 1 0 1 1 1 0 MMPL family Peptidase_M50 PF02163.22 EGG20204.1 - 0.11 11.7 7.6 0.8 8.9 2.6 3.0 1 1 1 3 3 3 0 Peptidase family M50 DUF5643 PF18705.1 EGG20205.1 - 5.9 6.9 9.1 5.6 7.0 0.4 3.8 4 0 0 4 4 4 0 Family of unknown function (DUF5643) G6PD_C PF02781.16 EGG20206.1 - 5.3e-99 331.1 0.0 1.1e-98 330.0 0.0 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EGG20206.1 - 3.1e-54 184.3 0.0 4.6e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ank_2 PF12796.7 EGG20207.1 - 0.0017 18.9 0.1 0.0099 16.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG20207.1 - 0.055 14.1 0.6 2.6 8.8 0.0 3.5 3 1 1 4 4 4 0 Ankyrin repeats (many copies) CHORD PF04968.12 EGG20208.1 - 1.2e-46 157.3 19.4 1.5e-23 83.3 5.2 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.16 EGG20208.1 - 1.7e-13 51.4 1.7 1.7e-13 51.4 1.7 1.9 2 0 0 2 2 2 1 CS domain BTK PF00779.19 EGG20208.1 - 0.061 13.2 6.9 0.66 9.8 1.7 3.0 2 0 0 2 2 2 0 BTK motif Atg8 PF02991.16 EGG20209.1 - 6.8e-33 113.0 0.0 8.4e-33 112.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EGG20209.1 - 1.2e-05 25.6 0.0 1.7e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 FNIP PF05725.12 EGG20210.1 - 5.6e-05 23.2 35.4 0.003 17.7 0.2 9.4 7 2 0 7 7 7 3 FNIP Repeat APG6_N PF17675.1 EGG20210.1 - 0.00051 20.6 60.3 0.016 15.7 13.4 3.7 3 0 0 3 3 3 3 Apg6 coiled-coil region WXG100 PF06013.12 EGG20210.1 - 0.012 15.8 5.6 1.5 9.1 0.2 3.1 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Img2 PF05046.14 EGG20210.1 - 2 8.7 4.7 3.8 7.9 1.3 2.9 2 1 1 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) DUF948 PF06103.11 EGG20210.1 - 3.8 7.8 7.3 1.9 8.8 0.3 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FNIP PF05725.12 EGG20212.1 - 1.1e-14 54.2 21.3 4.7e-05 23.5 0.0 8.0 6 2 2 8 8 8 5 FNIP Repeat LRR_4 PF12799.7 EGG20212.1 - 5 7.7 17.3 56 4.4 1.3 7.4 6 2 2 8 8 8 0 Leucine Rich repeats (2 copies) Ras PF00071.22 EGG20213.1 - 1.6e-28 99.3 0.2 7.9e-28 97.1 0.0 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGG20213.1 - 4.8e-08 33.2 0.0 2e-07 31.3 0.0 2.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase STATa_Ig PF18214.1 EGG20213.1 - 1.4e-07 31.5 0.7 3.7e-07 30.2 0.1 2.1 2 0 0 2 2 2 1 STATa Immunoglobulin-like domain Arf PF00025.21 EGG20213.1 - 0.0022 17.5 0.0 0.0067 15.9 0.0 1.9 1 0 0 1 1 1 1 ADP-ribosylation factor family Pex2_Pex12 PF04757.14 EGG20214.1 - 8e-41 140.1 5.1 1.2e-40 139.5 5.1 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 EGG20214.1 - 1.3e-06 28.2 4.9 2.3e-06 27.3 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG20214.1 - 2.3e-05 24.3 7.2 4.4e-05 23.4 7.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG20214.1 - 3.8e-05 23.4 4.2 6.8e-05 22.6 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG20214.1 - 8e-05 22.4 3.8 0.00014 21.7 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG20214.1 - 0.00052 20.3 5.0 0.00093 19.5 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGG20214.1 - 0.0013 18.6 4.2 0.0025 17.7 4.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGG20214.1 - 0.031 14.4 8.4 0.059 13.5 8.4 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGG20214.1 - 0.13 12.6 1.0 0.28 11.5 1.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Tim17 PF02466.19 EGG20214.1 - 0.15 12.5 0.5 0.34 11.3 0.5 1.6 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Prok-RING_4 PF14447.6 EGG20214.1 - 0.3 11.0 6.7 2.2 8.2 7.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FAD_binding_3 PF01494.19 EGG20215.1 - 3e-29 102.4 0.0 4.4e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 EGG20215.1 - 0.00071 18.7 0.0 0.0015 17.7 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.27 EGG20215.1 - 0.0029 18.1 1.4 0.011 16.2 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGG20215.1 - 0.0071 15.6 1.4 0.091 12.0 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG20215.1 - 0.074 12.3 3.2 1.1 8.5 0.0 2.9 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGG20215.1 - 0.082 11.7 1.7 0.38 9.5 0.1 2.5 3 1 0 3 3 3 0 Tryptophan halogenase VIT1 PF01988.19 EGG20216.1 - 0.56 10.0 2.6 4.2 7.2 2.6 2.3 1 1 0 1 1 1 0 VIT family SNAP PF14938.6 EGG20217.1 - 1.4e-20 73.9 17.7 1.8e-20 73.5 17.7 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 EGG20217.1 - 0.0018 17.7 3.7 0.0031 16.9 1.1 2.4 1 1 1 3 3 3 1 MalT-like TPR region TPR_14 PF13428.6 EGG20217.1 - 0.0098 16.6 3.5 12 7.0 0.3 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat EF-hand_like PF09279.11 EGG20217.1 - 0.011 16.2 0.9 0.042 14.3 0.2 2.4 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like TPR_12 PF13424.6 EGG20217.1 - 0.015 15.6 6.5 0.017 15.4 0.8 2.9 1 1 1 3 3 3 0 Tetratricopeptide repeat YfdX PF10938.8 EGG20217.1 - 0.54 10.2 6.7 0.31 11.0 0.5 2.8 3 0 0 3 3 3 0 YfdX protein DUF357 PF04010.13 EGG20217.1 - 0.73 9.9 3.0 2.4 8.3 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF357) UbiA PF01040.18 EGG20218.1 - 6e-15 55.2 20.5 1e-14 54.4 20.5 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3446 PF11928.8 EGG20218.1 - 0.02 15.2 2.8 0.02 15.2 2.8 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Maelstrom PF13017.6 EGG20218.1 - 0.098 12.3 0.4 0.33 10.6 0.1 1.9 2 0 0 2 2 2 0 piRNA pathway germ-plasm component ESSS PF10183.9 EGG20218.1 - 0.24 11.6 0.8 5.4 7.3 0.0 2.7 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FNIP PF05725.12 EGG20219.1 - 0.00084 19.5 16.9 11 6.2 0.3 7.3 5 2 1 6 6 6 4 FNIP Repeat TMEM151 PF14857.6 EGG20220.1 - 1.3e-05 24.4 1.6 0.00099 18.1 1.6 2.2 1 1 0 1 1 1 1 TMEM151 family SKG6 PF08693.10 EGG20221.1 - 0.0022 17.4 0.8 0.0041 16.5 0.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EGF_2 PF07974.13 EGG20221.1 - 0.014 15.8 33.1 0.024 15.0 13.5 3.0 3 0 0 3 3 3 0 EGF-like domain Macro PF01661.21 EGG20222.1 - 6.5e-25 87.5 0.2 9e-25 87.0 0.2 1.2 1 0 0 1 1 1 1 Macro domain Zn_Tnp_IS91 PF14319.6 EGG20223.1 - 0.0048 16.9 1.0 0.0048 16.9 1.0 1.8 1 1 1 2 2 2 1 Transposase zinc-binding domain PI-PLC-Y PF00387.19 EGG20224.1 - 7.3e-33 113.3 0.0 1.8e-32 112.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PI-PLC-X PF00388.19 EGG20224.1 - 5.7e-32 110.3 3.2 9e-17 61.0 0.1 2.7 1 1 1 2 2 2 2 Phosphatidylinositol-specific phospholipase C, X domain C2 PF00168.30 EGG20224.1 - 3.3e-18 65.9 0.0 1e-17 64.3 0.0 1.9 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 EGG20224.1 - 1.6e-08 34.9 0.2 5.5e-08 33.2 0.2 2.0 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.6 EGG20224.1 - 0.0091 16.4 1.1 0.07 13.6 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EGG20224.1 - 0.036 13.9 0.1 0.1 12.4 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 EGG20224.1 - 0.2 11.3 2.5 0.31 10.7 0.4 2.6 2 0 0 2 2 2 0 EF hand PI-PLC-X PF00388.19 EGG20225.1 - 1.4e-56 190.1 0.2 3.5e-56 188.8 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGG20225.1 - 7.5e-33 113.3 0.0 7.5e-33 113.3 0.0 2.6 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGG20225.1 - 4.8e-19 68.6 0.4 9e-18 64.5 0.0 2.9 3 0 0 3 3 3 1 C2 domain EF-hand_like PF09279.11 EGG20225.1 - 2.4e-05 24.7 0.8 2.4e-05 24.7 0.8 2.3 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.6 EGG20225.1 - 0.00034 21.0 0.1 0.0092 16.4 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair PH_12 PF16457.5 EGG20225.1 - 0.0052 17.3 0.2 0.0052 17.3 0.2 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain EF-hand_1 PF00036.32 EGG20225.1 - 0.0089 15.5 1.1 0.031 13.8 0.1 2.5 2 0 0 2 2 2 1 EF hand GDPD PF03009.17 EGG20225.1 - 0.009 15.8 0.1 0.026 14.3 0.1 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_8 PF13833.6 EGG20225.1 - 0.022 14.6 0.0 0.06 13.2 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair DUF1729 PF08354.10 EGG20225.1 - 0.11 11.4 0.2 2.2 7.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1729) EF-hand_6 PF13405.6 EGG20225.1 - 0.17 11.9 0.6 5.2 7.3 0.2 3.4 2 1 1 3 3 3 0 EF-hand domain FAD_binding_1 PF00667.20 EGG20226.1 - 7.8e-43 146.6 0.0 1.2e-42 146.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGG20226.1 - 1.9e-27 96.3 0.0 3.2e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGG20226.1 - 7.4e-11 42.7 0.0 1.3e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain COX7C PF02935.16 EGG20227.1 - 0.19 12.0 2.4 0.4 11.0 2.4 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Rap_GAP PF02145.15 EGG20228.1 - 1.6e-50 171.3 0.0 5.5e-50 169.5 0.0 2.0 1 0 0 1 1 1 1 Rap/ran-GAP UpxZ PF06603.11 EGG20228.1 - 0.12 12.6 0.3 0.66 10.3 0.1 2.4 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists EGF_2 PF07974.13 EGG20230.1 - 3.1e-06 27.4 15.0 6.9e-06 26.3 15.0 1.6 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG20230.1 - 0.00026 21.0 12.0 0.0008 19.4 12.0 1.9 1 0 0 1 1 1 1 Tenascin EGF domain EGF PF00008.27 EGG20230.1 - 0.0012 19.1 8.1 0.0038 17.5 8.1 1.9 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 EGG20230.1 - 0.51 11.0 10.3 0.17 12.5 6.6 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF Laminin_EGF PF00053.24 EGG20230.1 - 0.6 10.3 11.3 1.4 9.1 11.3 1.6 1 0 0 1 1 1 0 Laminin EGF domain EGF_alliinase PF04863.13 EGG20230.1 - 1.1 9.7 9.2 3.4 8.2 9.2 1.8 1 1 0 1 1 1 0 Alliinase EGF-like domain DUF3978 PF13123.6 EGG20230.1 - 1.4 8.7 7.2 0.49 10.1 3.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3978) Asp_protease PF09668.10 EGG20231.1 - 5.4e-54 181.3 0.5 9.4e-54 180.5 0.5 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGG20231.1 - 3.5e-20 72.4 0.1 6.4e-20 71.5 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGG20231.1 - 1.2e-08 35.4 0.1 2.3e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease UBA_4 PF14555.6 EGG20231.1 - 2.3e-05 24.1 0.0 5.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain RVP_2 PF08284.11 EGG20231.1 - 0.00018 21.3 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 EGG20231.1 - 0.0014 18.9 0.0 0.0035 17.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease EBP50_C PF09007.11 EGG20231.1 - 0.3 12.1 3.4 0.59 11.1 3.4 1.4 1 0 0 1 1 1 0 EBP50, C-terminal Elongin_A PF06881.11 EGG20232.1 - 3.3e-19 69.4 2.1 5.2e-19 68.7 2.1 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A SRP-alpha_N PF04086.13 EGG20232.1 - 0.015 15.3 7.5 0.019 14.9 7.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Herpes_capsid PF06112.11 EGG20232.1 - 0.018 15.1 10.6 0.026 14.6 10.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Dynamin_M PF01031.20 EGG20232.1 - 0.021 14.1 0.3 0.029 13.6 0.3 1.2 1 0 0 1 1 1 0 Dynamin central region AF-4 PF05110.13 EGG20232.1 - 0.029 12.5 18.8 0.038 12.1 18.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ELL PF10390.9 EGG20232.1 - 0.032 13.7 5.5 0.051 13.1 5.5 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Macoilin PF09726.9 EGG20232.1 - 0.042 12.4 10.9 0.049 12.2 10.9 1.1 1 0 0 1 1 1 0 Macoilin family ATP11 PF06644.11 EGG20232.1 - 0.053 13.3 4.7 0.073 12.8 4.7 1.2 1 0 0 1 1 1 0 ATP11 protein CCDC24 PF15669.5 EGG20232.1 - 0.2 11.5 5.3 0.27 11.1 5.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family RAP1 PF07218.11 EGG20232.1 - 1.9 6.6 15.3 2.5 6.3 15.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 EGG20232.1 - 4.6 6.8 31.4 13 5.3 31.4 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TMA7 PF09072.10 EGG20233.1 - 1e-24 87.1 19.9 1.5e-24 86.5 19.9 1.3 1 0 0 1 1 1 1 Translation machinery associated TMA7 Nucleoporin_FG PF13634.6 EGG20234.1 - 3.1e-19 69.6 284.6 1.7e-09 38.4 26.9 17.0 13 4 3 16 16 16 10 Nucleoporin FG repeat region Cuticle_3 PF11018.8 EGG20234.1 - 2.3e-05 24.7 1.6 0.00042 20.6 0.6 6.7 5 1 2 7 7 7 3 Pupal cuticle protein C1 CDC45 PF02724.14 EGG20234.1 - 0.00096 17.6 10.3 0.00096 17.6 10.3 8.6 5 2 2 7 7 7 1 CDC45-like protein zf-RanBP PF00641.18 EGG20234.1 - 0.0036 16.6 54.7 0.091 12.1 8.0 4.5 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others Pho88 PF10032.9 EGG20235.1 - 1.6e-35 122.0 0.0 2.6e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Phosphate transport (Pho88) EBV-NA3 PF05009.12 EGG20235.1 - 0.0049 16.4 0.2 0.0079 15.8 0.2 1.3 1 0 0 1 1 1 1 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Oxidored_q3 PF00499.20 EGG20235.1 - 0.057 13.1 0.1 7.3 6.3 0.4 2.2 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 USP19_linker PF16602.5 EGG20235.1 - 0.13 12.9 2.3 0.24 11.9 2.3 1.4 1 0 0 1 1 1 0 Linker region of USP19 deubiquitinase FAM176 PF14851.6 EGG20235.1 - 0.19 11.4 0.3 2.4 7.8 0.0 2.0 2 0 0 2 2 2 0 FAM176 family RPN6_N PF18055.1 EGG20236.1 - 4.2e-24 85.2 2.5 3.4e-23 82.2 0.4 3.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EGG20236.1 - 2.1e-17 63.5 1.1 1.1e-16 61.2 0.3 2.7 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 EGG20236.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain Pet191_N PF10203.9 EGG20237.1 - 1.6e-22 79.6 6.9 2.1e-22 79.2 6.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EGG20237.1 - 0.084 12.9 7.9 0.34 10.9 2.5 2.7 2 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DRAT PF07357.11 EGG20237.1 - 0.17 11.1 0.2 0.18 10.9 0.2 1.1 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) Cullin_Nedd8 PF10557.9 EGG20237.1 - 0.17 11.9 1.5 1.3 9.1 0.3 2.5 2 1 0 2 2 2 0 Cullin protein neddylation domain CHCH PF06747.13 EGG20237.1 - 7.7 6.8 11.8 0.52 10.5 5.1 2.1 2 0 0 2 2 2 0 CHCH domain BTB_2 PF02214.22 EGG20238.1 - 6.8e-57 189.8 9.6 1.2e-17 64.0 0.2 4.6 4 0 0 4 4 4 4 BTB/POZ domain TLD PF07534.16 EGG20238.1 - 1.6e-55 187.2 18.4 4.5e-21 75.5 3.4 3.7 3 0 0 3 3 3 3 TLD Fib_alpha PF08702.10 EGG20238.1 - 1.3e-05 25.5 12.7 0.29 11.3 0.5 4.4 4 0 0 4 4 4 2 Fibrinogen alpha/beta chain family DUF2634 PF10934.8 EGG20238.1 - 0.0017 18.4 16.2 1.9 8.7 0.7 5.1 4 1 1 5 5 5 2 Protein of unknown function (DUF2634) Ycf54 PF10674.9 EGG20238.1 - 0.0024 18.1 0.4 7.6 6.9 0.0 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF2488) Prefoldin_2 PF01920.20 EGG20238.1 - 0.0035 17.3 18.5 1.6 8.7 1.2 4.5 4 0 0 4 4 4 3 Prefoldin subunit DASH_Dam1 PF08653.10 EGG20238.1 - 0.012 15.4 5.8 20 5.1 0.0 4.5 4 0 0 4 4 4 0 DASH complex subunit Dam1 Tox-ODYAM1 PF15642.6 EGG20238.1 - 0.096 11.6 7.5 1.4 7.8 0.3 2.7 3 0 0 3 3 3 0 Toxin in Odyssella and Amoebophilus DUF3467 PF11950.8 EGG20238.1 - 0.1 12.8 0.2 31 4.8 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) DUF4140 PF13600.6 EGG20238.1 - 0.21 12.1 13.2 8.4 6.9 0.4 4.3 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) ITAM_Cys-rich PF10538.9 EGG20238.1 - 0.25 11.1 0.3 1.6e+02 2.2 0.0 3.5 3 0 0 3 3 3 0 Immunoreceptor tyrosine-based activation motif TPR_MLP1_2 PF07926.12 EGG20238.1 - 1.1 9.3 19.6 1.2 9.3 1.0 4.2 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein Prefoldin PF02996.17 EGG20238.1 - 1.3 9.0 17.7 7.2 6.6 0.0 4.7 5 0 0 5 5 5 0 Prefoldin subunit DUF5082 PF16888.5 EGG20238.1 - 2.8 8.2 21.0 7.9 6.8 0.2 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) DegQ PF08181.11 EGG20238.1 - 4.7 7.4 21.0 8.3 6.6 0.4 4.9 4 0 0 4 4 4 0 DegQ (SacQ) family DUF2383 PF09537.10 EGG20238.1 - 6.2 7.2 13.2 24 5.3 0.2 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF2383) BTB_2 PF02214.22 EGG20239.1 - 5.1e-08 33.2 0.1 9.5e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain LSM14 PF12701.7 EGG20241.1 - 3e-25 88.1 0.1 7.4e-25 86.8 0.1 1.7 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 EGG20241.1 - 3.4e-08 33.5 0.1 9.6e-08 32.1 0.1 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 EGG20241.1 - 4.2e-08 34.0 5.5 4.2e-08 34.0 5.5 4.3 3 1 2 5 5 5 1 FDF domain Med12 PF09497.10 EGG20242.1 - 6.7e-16 58.3 0.1 1.7e-15 57.0 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 EGG20242.1 - 1.5e-06 27.4 3.8 1.5e-06 27.4 3.8 4.8 4 1 0 4 4 4 1 Eukaryotic Mediator 12 subunit domain TFIIA PF03153.13 EGG20242.1 - 0.00059 19.9 35.7 0.00059 19.9 35.7 5.6 5 2 0 5 5 5 1 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 EGG20242.1 - 8.5 5.5 6.4 21 4.2 6.4 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter SapB_2 PF03489.17 EGG20243.1 - 3e-16 59.2 15.8 5.8e-08 32.7 3.6 3.4 3 0 0 3 3 3 2 Saposin-like type B, region 2 SapB_1 PF05184.15 EGG20243.1 - 4e-11 42.7 6.2 2.3e-08 33.9 0.3 4.0 3 0 0 3 3 3 2 Saposin-like type B, region 1 PLAC9 PF15205.6 EGG20243.1 - 0.24 11.8 1.4 0.7 10.3 1.4 1.8 1 0 0 1 1 1 0 Placenta-specific protein 9 Salp15 PF12115.8 EGG20243.1 - 1.6 9.2 11.1 22 5.5 6.2 2.6 2 1 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation SAC3 PF12209.8 EGG20243.1 - 3.7 7.8 5.9 1.8 8.8 0.4 2.9 4 0 0 4 4 4 0 Leucine permease transcriptional regulator helical domain MRP-S34 PF16053.5 EGG20244.1 - 1e-08 34.9 0.1 1.4e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 BSD PF03909.17 EGG20245.1 - 7.5e-07 29.1 1.7 7.5e-07 29.1 1.7 2.2 2 0 0 2 2 2 1 BSD domain IBR PF01485.21 EGG20245.1 - 6e-06 26.4 11.0 6e-06 26.4 11.0 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EGG20245.1 - 0.00016 21.5 5.8 0.00016 21.5 5.8 4.7 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG20245.1 - 0.00064 19.5 6.9 0.00064 19.5 6.9 5.0 3 2 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG20245.1 - 0.0022 17.8 6.1 0.0022 17.8 6.1 4.5 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG20245.1 - 0.0025 17.8 6.8 0.0025 17.8 6.8 4.0 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGG20245.1 - 0.015 15.6 8.8 0.015 15.6 8.8 4.1 4 0 0 4 4 4 0 Ring finger domain NeA_P2 PF12312.8 EGG20245.1 - 2.7 7.4 10.9 0.15 11.5 0.2 2.3 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein Snf7 PF03357.21 EGG20246.1 - 3.5e-28 98.3 16.4 3.5e-28 98.3 16.4 1.4 1 1 0 1 1 1 1 Snf7 Menin PF05053.13 EGG20249.1 - 0.29 9.5 1.0 0.44 8.8 1.0 1.2 1 0 0 1 1 1 0 Menin Paramecium_SA PF01508.16 EGG20250.1 - 0.0022 18.3 19.2 0.16 12.4 10.8 2.8 1 1 0 2 2 2 2 Paramecium surface antigen domain Trypan_glycop_C PF10659.9 EGG20250.1 - 3.5 8.1 16.1 8.3 6.8 0.3 3.0 2 1 0 3 3 3 0 Trypanosome variant surface glycoprotein C-terminal domain Paramecium_SA PF01508.16 EGG20251.1 - 6.5e-05 23.3 20.0 0.00018 21.9 10.1 2.2 1 1 1 2 2 2 2 Paramecium surface antigen domain PSI PF01437.25 EGG20251.1 - 0.0028 18.2 21.0 0.14 12.7 0.9 3.1 1 1 2 3 3 3 3 Plexin repeat XRN_N PF03159.18 EGG20252.1 - 7.7e-47 159.8 0.1 7.7e-47 159.8 0.1 2.8 2 1 1 3 3 3 1 XRN 5'-3' exonuclease N-terminus XPG_I_2 PF12813.7 EGG20252.1 - 0.26 10.7 0.0 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 XPG domain containing TFIIA PF03153.13 EGG20252.1 - 0.83 9.6 51.4 2.6 8.0 7.6 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LRR_4 PF12799.7 EGG20255.1 - 0.002 18.5 26.9 2.3 8.8 0.0 9.1 6 3 5 11 11 11 4 Leucine Rich repeats (2 copies) FNIP PF05725.12 EGG20255.1 - 0.007 16.5 26.5 0.97 9.7 5.8 7.2 7 2 1 8 8 8 4 FNIP Repeat PhyH PF05721.13 EGG20256.1 - 2.3e-48 165.2 0.0 2.7e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CRPA PF05745.11 EGG20257.1 - 3.1 7.8 9.3 4.3 7.3 0.7 2.8 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) LicD PF04991.13 EGG20258.1 - 0.038 14.1 0.4 0.047 13.8 0.4 1.1 1 0 0 1 1 1 0 LicD family INCENP_ARK-bind PF03941.15 EGG20259.1 - 4.2e-10 39.4 2.9 4.2e-10 39.4 2.9 3.4 4 1 0 4 4 4 1 Inner centromere protein, ARK binding region Cyt_bd_oxida_I PF01654.17 EGG20259.1 - 0.2 10.2 0.8 0.32 9.6 0.8 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I Kelch_4 PF13418.6 EGG20260.1 - 7.1e-39 131.6 4.7 2.9e-08 33.6 0.3 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGG20260.1 - 4.8e-34 116.0 7.8 1.4e-06 28.4 0.1 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG20260.1 - 9.5e-31 105.3 0.9 1.2e-05 25.1 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EGG20260.1 - 7.6e-22 76.8 9.1 1.4e-05 25.2 0.3 5.7 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EGG20260.1 - 2.6e-21 74.9 7.6 1.9e-06 27.4 0.6 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGG20260.1 - 1.3e-13 50.3 9.4 0.0081 16.1 0.2 6.2 6 0 0 6 6 6 4 Kelch motif zf-C3HC4_3 PF13920.6 EGG20260.1 - 0.00022 21.0 2.4 0.00046 20.0 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Borrelia_orfA PF02414.15 EGG20260.1 - 0.0012 18.6 19.2 0.0012 18.6 19.2 2.0 1 1 1 2 2 2 1 Borrelia ORF-A SPX PF03105.19 EGG20260.1 - 9.5 6.0 33.8 14 5.4 33.8 1.2 1 0 0 1 1 1 0 SPX domain Epimerase PF01370.21 EGG20261.1 - 9.2e-08 31.8 0.0 0.00094 18.7 0.0 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EGG20261.1 - 0.00019 21.4 0.3 0.00056 19.8 0.3 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EGG20261.1 - 0.00037 20.6 0.1 0.00054 20.0 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 EGG20261.1 - 0.0006 20.0 0.0 0.00099 19.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGG20261.1 - 0.0012 19.4 0.1 0.0026 18.3 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.6 EGG20261.1 - 0.0055 16.0 0.0 0.0067 15.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG20261.1 - 0.0056 17.2 0.1 0.015 15.8 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase DFP PF04127.15 EGG20261.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Sacchrp_dh_NADP PF03435.18 EGG20261.1 - 0.015 15.6 0.1 0.03 14.6 0.1 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 EGG20261.1 - 0.046 13.1 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EGG20261.1 - 0.053 12.8 0.1 0.079 12.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EGG20261.1 - 0.088 12.4 0.0 0.21 11.1 0.0 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EGG20261.1 - 0.092 12.7 0.1 0.17 11.9 0.1 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EGG20261.1 - 0.14 11.8 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF5494 PF17598.2 EGG20262.1 - 0.057 13.5 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5494) DNase_II PF03265.15 EGG20263.1 - 1.1e-76 258.2 9.7 1.3e-76 258.0 9.7 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II Cadherin-like PF12733.7 EGG20264.1 - 6.9 7.3 9.6 17 6.0 5.7 3.6 2 1 0 2 2 2 0 Cadherin-like beta sandwich domain CBM49 PF09478.10 EGG20265.1 - 0.00055 20.2 5.0 0.35 11.2 0.7 2.6 2 0 0 2 2 2 2 Carbohydrate binding domain CBM49 TAXi_C PF14541.6 EGG20265.1 - 0.0036 17.1 0.0 0.0084 15.9 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Response_reg PF00072.24 EGG20266.1 - 3.2e-20 72.3 1.2 4.1e-20 72.0 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain Asp PF00026.23 EGG20266.1 - 2.6e-09 37.0 0.5 2.2e-08 33.9 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGG20266.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal SUIM_assoc PF16619.5 EGG20266.1 - 5.6 7.1 16.7 0.13 12.4 8.1 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 C1_2 PF03107.16 EGG20267.1 - 0.001 19.4 8.8 0.0021 18.3 8.8 1.6 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 EGG20267.1 - 0.0061 16.4 5.7 0.011 15.6 5.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 EGG20267.1 - 0.0065 16.4 2.9 0.014 15.3 2.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Zf_RING PF16744.5 EGG20267.1 - 0.21 11.7 1.6 0.46 10.6 1.6 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-HIT PF04438.16 EGG20267.1 - 0.29 11.0 3.6 0.66 9.9 3.6 1.6 1 0 0 1 1 1 0 HIT zinc finger PHD PF00628.29 EGG20267.1 - 0.3 11.0 4.7 0.64 10.0 4.7 1.6 1 0 0 1 1 1 0 PHD-finger Cpn60_TCP1 PF00118.24 EGG20268.1 - 1.2e-21 76.9 5.3 2.9e-13 49.3 0.8 2.5 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Fis1_TPR_C PF14853.6 EGG20268.1 - 0.12 12.4 1.3 0.63 10.1 0.4 2.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF3522 PF12036.8 EGG20269.1 - 2.3e-46 158.5 4.2 2.9e-46 158.1 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF2721 PF11026.8 EGG20269.1 - 0.25 11.2 2.4 0.59 10.0 0.0 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2721) HlyIII PF03006.20 EGG20269.1 - 0.96 9.1 14.4 28 4.3 14.4 2.9 1 1 0 1 1 1 0 Haemolysin-III related Lipase_3 PF01764.25 EGG20270.1 - 8.1e-32 110.0 0.0 1.3e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EGG20270.1 - 0.00031 20.4 0.3 0.0013 18.4 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EGG20270.1 - 0.0028 18.3 0.0 0.0037 17.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EGG20270.1 - 0.0037 17.1 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG20270.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGG20270.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein fn3 PF00041.21 EGG20271.1 - 9.1e-07 29.1 81.5 0.058 13.7 0.5 14.2 13 1 1 14 14 14 7 Fibronectin type III domain Tissue_fac PF01108.17 EGG20271.1 - 2.5e-05 24.1 31.9 0.43 10.4 1.2 9.0 8 1 0 8 8 8 3 Tissue factor DUF2369 PF10179.9 EGG20271.1 - 0.00022 21.5 5.1 0.0043 17.4 0.3 8.3 10 1 0 10 10 10 2 Uncharacterised conserved protein (DUF2369) IL17R_fnIII_D2 PF16578.5 EGG20271.1 - 0.0049 17.4 3.2 1.8 9.2 0.2 4.2 3 0 0 3 3 3 2 Interleukin 17 receptor D PhoD_N PF16655.5 EGG20271.1 - 0.077 13.5 0.8 29 5.3 0.1 4.2 4 0 0 4 4 4 0 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 EGG20272.1 - 0.00091 19.5 37.3 0.015 15.6 1.3 7.6 7 0 0 7 7 7 4 Fibronectin type III domain DUF2369 PF10179.9 EGG20272.1 - 0.0039 17.5 1.1 0.0039 17.5 1.1 4.1 5 0 0 5 5 5 1 Uncharacterised conserved protein (DUF2369) Tissue_fac PF01108.17 EGG20272.1 - 0.031 14.1 12.3 2.4 8.0 0.9 4.9 4 0 0 4 4 4 0 Tissue factor DUF4811 PF16069.5 EGG20274.1 - 0.051 13.4 1.4 0.13 12.1 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) TIG PF01833.24 EGG20275.1 - 4e-51 171.0 152.4 5e-06 26.5 4.2 17.3 16 2 2 18 18 18 15 IPT/TIG domain EGF_2 PF07974.13 EGG20275.1 - 7.5e-05 23.0 15.6 0.00015 22.0 15.6 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG20275.1 - 0.0015 18.5 13.6 0.0055 16.7 13.6 2.1 1 0 0 1 1 1 1 Tenascin EGF domain EGF PF00008.27 EGG20275.1 - 0.01 16.1 8.4 0.024 14.9 8.4 1.7 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 EGG20275.1 - 1.9 8.7 11.2 3.9 7.7 11.2 1.5 1 0 0 1 1 1 0 Laminin EGF domain EGF_alliinase PF04863.13 EGG20275.1 - 2.5 8.6 7.3 5.6 7.4 7.3 1.6 1 0 0 1 1 1 0 Alliinase EGF-like domain DSL PF01414.19 EGG20275.1 - 4.2 7.7 7.7 11 6.4 7.7 1.7 1 0 0 1 1 1 0 Delta serrate ligand hEGF PF12661.7 EGG20275.1 - 5.2 7.8 12.2 1.4 9.6 8.2 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF KdpC PF02669.15 EGG20276.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Spt20 PF12090.8 EGG20276.1 - 0.6 9.7 7.0 4.1 6.9 2.3 2.3 2 0 0 2 2 2 0 Spt20 family TIG PF01833.24 EGG20278.1 - 5.8e-42 141.7 209.2 1.2e-05 25.3 2.3 22.5 17 3 5 22 22 22 17 IPT/TIG domain EGF_2 PF07974.13 EGG20278.1 - 0.00011 22.5 15.6 0.00023 21.5 15.6 1.6 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG20278.1 - 0.0022 18.0 13.6 0.0083 16.2 13.6 2.1 1 0 0 1 1 1 1 Tenascin EGF domain EGF PF00008.27 EGG20278.1 - 0.016 15.5 8.4 0.037 14.4 8.4 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGG20278.1 - 0.64 10.7 8.2 2.2 9.1 8.2 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_alliinase PF04863.13 EGG20278.1 - 2.7 8.5 7.3 8.4 6.9 7.3 1.9 1 0 0 1 1 1 0 Alliinase EGF-like domain Laminin_EGF PF00053.24 EGG20278.1 - 2.8 8.2 11.2 5.9 7.1 11.2 1.5 1 0 0 1 1 1 0 Laminin EGF domain Nop52 PF05997.12 EGG20279.1 - 3.3e-41 141.4 0.4 1.2e-40 139.7 0.4 2.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 NPH3 PF03000.14 EGG20279.1 - 0.0025 17.5 0.1 0.005 16.5 0.1 1.5 1 0 0 1 1 1 1 NPH3 family MIF4G_like_2 PF09090.11 EGG20279.1 - 0.0097 15.4 0.9 0.0097 15.4 0.9 2.7 2 1 0 2 2 2 1 MIF4G like HXXSHH PF07586.11 EGG20279.1 - 0.072 12.7 0.2 0.2 11.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Inhibitor_I29 PF08246.12 EGG20281.1 - 1.2e-11 44.8 0.0 1.2e-11 44.8 0.0 2.4 2 1 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) MgtC PF02308.16 EGG20281.1 - 0.022 15.1 0.5 0.033 14.5 0.5 1.2 1 0 0 1 1 1 0 MgtC family LapA_dom PF06305.11 EGG20281.1 - 0.45 10.4 2.2 0.64 9.9 0.8 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain VWA_N PF08399.11 EGG20281.1 - 0.46 11.0 4.7 0.29 11.6 1.0 2.2 2 0 0 2 2 2 0 VWA N-terminal DUF3042 PF11240.8 EGG20281.1 - 8.8 6.4 6.7 4 7.6 3.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3042) Peptidase_C1 PF00112.23 EGG20282.1 - 4e-50 170.9 3.5 6e-50 170.3 3.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.26 EGG20282.1 - 3e-09 37.8 0.3 7e-09 36.6 0.3 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_C1_2 PF03051.15 EGG20282.1 - 0.0003 19.7 0.6 0.21 10.4 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Mito_carr PF00153.27 EGG20284.1 - 1.5e-66 220.4 8.0 5.3e-25 87.2 0.6 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.16 EGG20284.1 - 0.0068 16.3 1.9 1.6 8.7 0.0 3.7 3 1 1 4 4 4 1 UcrQ family Glyco_hydro2_C5 PF18565.1 EGG20284.1 - 0.048 13.5 0.2 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Glycoside hydrolase family 2 C-terminal domain 5 ThrE_2 PF12821.7 EGG20284.1 - 0.25 11.5 3.7 3 8.0 0.4 2.8 3 0 0 3 3 3 0 Threonine/Serine exporter, ThrE FYVE PF01363.21 EGG20285.1 - 1e-17 64.0 13.5 1e-17 64.0 13.5 1.9 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 EGG20285.1 - 2.9e-12 47.0 9.8 2.1e-09 37.8 0.1 4.0 4 1 0 4 4 4 2 PH domain PH_11 PF15413.6 EGG20285.1 - 0.0002 21.7 2.8 0.0002 21.7 2.8 4.2 2 2 1 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.6 EGG20285.1 - 0.00088 19.5 0.0 0.91 9.8 0.0 3.2 3 0 0 3 3 3 2 Pleckstrin homology domain Reo_sigmaC_M PF17750.1 EGG20285.1 - 0.026 14.4 1.5 0.038 13.9 0.0 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein triple beta spiral Tim54 PF11711.8 EGG20285.1 - 0.49 9.1 6.0 0.069 11.9 1.5 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 IBR PF01485.21 EGG20285.1 - 2.8 8.2 13.9 0.83 9.9 9.6 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 EGG20285.1 - 3.1 8.1 16.6 0.049 13.8 8.6 2.0 2 1 0 2 2 2 0 FYVE-type zinc finger EF1_GNE PF00736.19 EGG20287.1 - 8.8e-25 86.7 2.1 1.9e-24 85.6 2.1 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_3 PF14497.6 EGG20287.1 - 0.047 13.9 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGG20287.1 - 0.062 13.1 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EGF_2 PF07974.13 EGG20288.1 - 0.00038 20.8 12.6 0.0011 19.3 12.6 1.8 1 0 0 1 1 1 1 EGF-like domain LRR19-TM PF15176.6 EGG20288.1 - 0.031 14.3 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain CD34_antigen PF06365.12 EGG20288.1 - 0.043 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family EGF_3 PF12947.7 EGG20288.1 - 0.2 11.9 4.6 0.85 9.9 4.6 2.1 1 0 0 1 1 1 0 EGF domain NupH_GANP PF16768.5 EGG20288.1 - 1.5 8.4 10.4 0.1 12.3 1.6 2.8 3 0 0 3 3 3 0 Nucleoporin homology of Germinal-centre associated nuclear protein TIG PF01833.24 EGG20289.1 - 3.4e-20 71.9 166.3 0.00017 21.6 4.8 18.7 16 3 3 19 19 19 12 IPT/TIG domain EGF_2 PF07974.13 EGG20289.1 - 0.00012 22.4 15.6 0.00028 21.2 15.6 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG20289.1 - 0.0038 17.2 13.6 0.01 15.9 13.6 1.8 1 0 0 1 1 1 1 Tenascin EGF domain EGF PF00008.27 EGG20289.1 - 0.012 15.9 8.4 0.045 14.1 8.4 2.1 1 0 0 1 1 1 0 EGF-like domain CoA_trans PF01144.23 EGG20289.1 - 0.11 11.8 0.3 0.24 10.8 0.3 1.5 1 0 0 1 1 1 0 Coenzyme A transferase Qn_am_d_aIII PF09099.10 EGG20289.1 - 0.28 11.6 2.0 3.2 8.2 0.1 2.9 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III hEGF PF12661.7 EGG20289.1 - 0.42 11.3 8.2 2.6 8.8 8.2 2.6 1 0 0 1 1 1 0 Human growth factor-like EGF Laminin_EGF PF00053.24 EGG20289.1 - 2.6 8.3 11.2 7.2 6.8 11.2 1.8 1 0 0 1 1 1 0 Laminin EGF domain EGF_alliinase PF04863.13 EGG20289.1 - 3.3 8.2 7.8 10 6.6 7.3 2.1 2 0 0 2 2 2 0 Alliinase EGF-like domain TIG PF01833.24 EGG20290.1 - 3.3e-40 136.1 135.1 4.9e-07 29.7 0.5 15.0 15 0 0 15 15 15 13 IPT/TIG domain EGF_2 PF07974.13 EGG20290.1 - 0.00016 22.0 15.6 0.00016 22.0 15.6 1.7 2 0 0 2 2 2 1 EGF-like domain EGF_Tenascin PF18720.1 EGG20290.1 - 0.0058 16.7 13.6 0.0058 16.7 13.6 2.3 2 0 0 2 2 2 1 Tenascin EGF domain EGF PF00008.27 EGG20290.1 - 0.011 16.0 8.4 0.026 14.8 8.4 1.6 1 0 0 1 1 1 0 EGF-like domain vWF_A PF12450.8 EGG20290.1 - 0.04 13.9 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor hEGF PF12661.7 EGG20290.1 - 0.43 11.3 8.2 1.5 9.6 8.2 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF Laminin_EGF PF00053.24 EGG20290.1 - 2.1 8.6 11.2 4.1 7.6 11.2 1.4 1 0 0 1 1 1 0 Laminin EGF domain EGF_alliinase PF04863.13 EGG20290.1 - 2.4 8.6 7.3 5.9 7.4 7.3 1.7 1 0 0 1 1 1 0 Alliinase EGF-like domain 7TMR-DISM_7TM PF07695.11 EGG20291.1 - 0.0035 17.3 13.7 0.0035 17.3 13.7 2.2 1 1 0 2 2 2 1 7TM diverse intracellular signalling AbrB PF05145.12 EGG20291.1 - 0.012 14.6 1.7 0.023 13.7 1.7 1.5 1 0 0 1 1 1 0 Transition state regulatory protein AbrB Peptidase_M66 PF10462.9 EGG20292.1 - 1.8e-90 303.0 0.9 3e-90 302.3 0.7 1.4 2 0 0 2 2 2 1 Peptidase M66 Reprolysin_3 PF13582.6 EGG20292.1 - 0.0069 16.9 0.1 0.018 15.6 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EGG20292.1 - 0.053 13.2 0.7 0.14 11.8 0.7 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 EGG20292.1 - 0.073 11.7 0.2 0.12 11.0 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase family DNA_pol_E_B PF04042.16 EGG20294.1 - 9.9e-28 96.9 3.0 9.9e-28 96.9 3.0 1.9 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Myb_DNA-binding PF00249.31 EGG20296.1 - 5.1e-07 29.8 0.0 2.5e-06 27.6 0.0 2.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Membrane_bind PF14564.6 EGG20297.1 - 7.8e-30 103.5 5.8 1.8e-29 102.4 0.0 3.6 4 0 0 4 4 4 1 Membrane binding Crystall_3 PF08964.10 EGG20297.1 - 3.5e-22 78.4 0.3 9.8e-22 76.9 0.3 1.8 1 0 0 1 1 1 1 Beta/Gamma crystallin TIG PF01833.24 EGG20297.1 - 4e-09 36.4 16.4 0.0094 16.0 2.2 5.0 4 0 0 4 4 4 3 IPT/TIG domain Lectin_C PF00059.21 EGG20297.1 - 0.00033 21.4 1.6 0.0068 17.1 0.2 3.2 3 0 0 3 3 3 1 Lectin C-type domain Crystall PF00030.19 EGG20297.1 - 0.00087 19.5 0.1 0.0022 18.2 0.1 1.7 1 0 0 1 1 1 1 Beta/Gamma crystallin EGF_2 PF07974.13 EGG20297.1 - 0.0016 18.7 9.8 0.0052 17.1 9.8 1.9 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 EGG20297.1 - 1 9.7 10.3 3 8.2 10.3 1.8 1 0 0 1 1 1 0 EGF-like domain RTP1_C1 PF10363.9 EGG20298.1 - 1.6e-05 25.1 0.9 7.3e-05 22.9 0.2 2.7 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EGG20298.1 - 3.3e-05 23.8 0.1 1.4 9.3 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EGG20298.1 - 0.032 14.6 0.0 2.8 8.4 0.0 2.9 2 0 0 2 2 2 0 HEAT repeats Tom22 PF04281.13 EGG20298.1 - 0.53 10.1 6.3 0.074 12.8 0.6 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Asp_protease PF09668.10 EGG20299.1 - 3e-54 182.1 0.4 5.1e-54 181.3 0.4 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGG20299.1 - 1e-20 74.0 0.1 2.1e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGG20299.1 - 4.1e-09 37.0 0.1 7.7e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 EGG20299.1 - 1.1e-06 28.3 0.8 3e-06 26.9 0.8 1.8 1 0 0 1 1 1 1 Ubiquitin family UBA_4 PF14555.6 EGG20299.1 - 1.3e-05 24.9 0.0 4.6e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 UBA-like domain RVP_2 PF08284.11 EGG20299.1 - 5.4e-05 23.0 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 EGG20299.1 - 0.0005 20.3 1.0 0.0011 19.2 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease RPA_interact_M PF14767.6 EGG20299.1 - 0.012 16.2 0.4 0.036 14.6 0.4 1.9 1 0 0 1 1 1 0 Replication protein A interacting middle UBA PF00627.31 EGG20299.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 UBA/TS-N domain Rad60-SLD PF11976.8 EGG20299.1 - 0.12 12.3 1.1 0.26 11.1 1.1 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CCDC53 PF10152.9 EGG20299.1 - 0.51 10.8 7.6 3.9 7.9 1.3 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Pex14_N PF04695.13 EGG20299.1 - 0.57 10.8 17.8 0.78 10.4 4.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 EGG20299.1 - 1.4 8.8 20.5 0.06 13.3 8.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EGG20299.1 - 1.6 7.3 9.4 1.7 7.3 1.1 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Androgen_recep PF02166.16 EGG20299.1 - 9 5.0 11.0 17 4.1 11.0 1.4 1 0 0 1 1 1 0 Androgen receptor TIG PF01833.24 EGG20300.1 - 3.9e-42 142.2 167.2 3.6e-08 33.4 4.4 17.5 17 1 0 17 17 17 14 IPT/TIG domain EGF_2 PF07974.13 EGG20300.1 - 9.5e-05 22.7 15.6 0.0002 21.7 15.6 1.6 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG20300.1 - 0.0026 17.8 13.6 0.0072 16.4 13.6 1.8 1 0 0 1 1 1 1 Tenascin EGF domain EGF PF00008.27 EGG20300.1 - 0.015 15.6 8.4 0.032 14.5 8.4 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGG20300.1 - 0.69 10.6 8.2 1.9 9.3 8.2 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF Laminin_EGF PF00053.24 EGG20300.1 - 2.5 8.3 11.2 5.1 7.3 11.2 1.5 1 0 0 1 1 1 0 Laminin EGF domain EGF_alliinase PF04863.13 EGG20300.1 - 3.4 8.2 7.3 7.3 7.1 7.3 1.5 1 0 0 1 1 1 0 Alliinase EGF-like domain TMEM154 PF15102.6 EGG20300.1 - 4.4 7.2 9.6 26 4.7 9.6 2.3 1 0 0 1 1 1 0 TMEM154 protein family SieB PF14163.6 EGG20301.1 - 0.064 12.8 0.9 0.072 12.6 0.1 1.5 2 0 0 2 2 2 0 Super-infection exclusion protein B TFCD_C PF12612.8 EGG20301.1 - 0.14 12.0 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal ABC2_membrane_3 PF12698.7 EGG20301.1 - 1.2 8.2 3.7 1.5 7.9 3.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DSPc PF00782.20 EGG20302.1 - 3.1e-27 95.0 0.0 3.1e-27 95.0 0.0 3.4 4 0 0 4 4 4 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 EGG20302.1 - 4e-05 23.4 0.1 0.0044 16.9 0.1 5.0 4 1 0 4 4 4 3 Gelsolin repeat Allexi_40kDa PF05549.11 EGG20303.1 - 0.037 13.5 1.3 0.04 13.4 1.3 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein F-box-like PF12937.7 EGG20304.1 - 7.9e-10 38.5 0.1 2e-09 37.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like GAS2 PF02187.17 EGG20304.1 - 0.00012 22.1 0.1 0.00057 19.9 0.1 2.3 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain F-box PF00646.33 EGG20304.1 - 0.0013 18.6 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain RRM_1 PF00076.22 EGG20305.1 - 1.6e-86 284.1 4.1 6e-21 74.0 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EGG20305.1 - 5e-20 71.5 0.3 1.4e-19 70.1 0.2 1.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EGG20305.1 - 3.2e-11 42.9 0.6 0.0072 15.9 0.0 4.3 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 EGG20305.1 - 4.8e-10 39.3 0.2 0.0012 18.8 0.1 4.0 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EGG20305.1 - 6.9e-08 32.3 0.0 0.1 12.5 0.0 4.6 4 1 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGG20305.1 - 2e-07 30.9 0.0 0.24 11.4 0.0 4.1 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGG20305.1 - 3.1e-05 23.9 1.3 5.5 7.1 0.1 4.5 3 1 1 4 4 4 1 RNA binding motif RRM_7 PF16367.5 EGG20305.1 - 0.00014 21.9 0.1 8.7 6.5 0.0 4.8 4 1 0 4 4 4 1 RNA recognition motif OB_RNB PF08206.11 EGG20305.1 - 0.0013 18.3 1.2 1 9.1 0.1 3.3 3 0 0 3 3 3 1 Ribonuclease B OB domain SET_assoc PF11767.8 EGG20305.1 - 0.0033 17.0 0.2 0.71 9.6 0.0 3.7 3 1 1 4 4 4 1 Histone lysine methyltransferase SET associated DUF4523 PF15023.6 EGG20305.1 - 0.12 12.2 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) LLC1 PF14945.6 EGG20305.1 - 0.15 12.6 0.1 0.56 10.8 0.1 2.0 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Coiled PF05710.12 EGG20306.1 - 0.018 15.9 2.6 0.02 15.7 2.6 1.1 1 0 0 1 1 1 0 Coiled coil DUF5407 PF17401.2 EGG20306.1 - 0.067 13.5 0.2 0.088 13.1 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5407) Nkap_C PF06047.11 EGG20307.1 - 1.1e-47 160.4 1.3 1.1e-47 160.4 1.3 2.6 2 1 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain eIF3_N PF09440.10 EGG20308.1 - 9e-17 61.8 2.3 4.3e-15 56.3 2.3 2.7 1 1 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EGG20308.1 - 1.3e-12 48.2 1.3 2.6e-12 47.1 0.5 2.0 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 EGG20308.1 - 0.0006 19.7 0.3 0.043 13.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG20308.1 - 0.0034 17.9 0.0 0.014 16.0 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF3050 PF11251.8 EGG20308.1 - 0.0084 15.8 0.4 0.024 14.3 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) TPR_8 PF13181.6 EGG20308.1 - 0.094 13.0 0.6 0.51 10.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Mucin PF01456.17 EGG20308.1 - 1.2 9.2 40.3 0.56 10.2 15.7 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Sporozoite_P67 PF05642.11 EGG20308.1 - 2.7 6.0 14.2 0.96 7.4 3.4 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Pex14_N PF04695.13 EGG20308.1 - 5.5 7.6 14.5 2.7 8.6 3.7 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SCP-1 PF05483.12 EGG20308.1 - 8.4 4.3 10.1 0.13 10.2 0.7 2.0 2 0 0 2 2 2 0 Synaptonemal complex protein 1 (SCP-1) AAA_22 PF13401.6 EGG20309.1 - 0.00022 21.5 0.1 0.00083 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EGG20309.1 - 0.00039 20.4 0.0 0.00039 20.4 0.0 3.4 4 1 0 4 4 4 1 ATPase domain predominantly from Archaea DNA_pol3_theta PF06440.11 EGG20309.1 - 0.006 16.2 0.1 0.006 16.2 0.1 2.3 3 0 0 3 3 3 1 DNA polymerase III, theta subunit AAA_18 PF13238.6 EGG20309.1 - 0.02 15.5 2.3 0.043 14.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EGG20309.1 - 0.04 14.3 0.3 0.37 11.2 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG20309.1 - 0.086 13.2 0.1 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain PSDC PF12588.8 EGG20309.1 - 0.11 12.5 1.5 3 7.8 0.2 2.8 2 0 0 2 2 2 0 Phophatidylserine decarboxylase NACHT PF05729.12 EGG20309.1 - 0.12 12.3 0.3 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EGG20309.1 - 0.16 12.5 5.0 0.26 11.8 0.0 3.3 4 0 0 4 4 4 0 ABC transporter RsgA_GTPase PF03193.16 EGG20309.1 - 0.43 10.5 3.7 6.1 6.7 0.0 3.8 4 0 0 4 4 4 0 RsgA GTPase DUF349 PF03993.12 EGG20309.1 - 2.4 8.5 6.4 0.91 9.9 2.5 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) AAA_11 PF13086.6 EGG20309.1 - 6.4 6.5 9.5 11 5.7 0.8 3.2 3 0 0 3 3 3 0 AAA domain LRR_4 PF12799.7 EGG20312.1 - 1.4e-26 92.1 44.8 1.8e-06 28.2 0.2 6.7 4 1 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG20312.1 - 3.8e-23 81.0 22.1 3.3e-07 30.0 0.2 5.0 3 1 1 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 EGG20312.1 - 6.9e-23 81.0 17.1 1.8e-12 47.1 1.8 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EGG20312.1 - 0.00017 21.4 25.3 6.6 7.1 0.1 8.8 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 EGG20312.1 - 1.8 9.4 18.8 17 6.4 0.2 7.5 8 1 0 8 8 8 0 Leucine Rich Repeat Lzipper-MIP1 PF14389.6 EGG20313.1 - 0.0034 17.7 1.1 0.0034 17.7 1.1 2.0 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Glyco_hydro_18 PF00704.28 EGG20314.1 - 1.2e-11 44.9 3.1 1.5e-11 44.6 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FAM60A PF15396.6 EGG20315.1 - 0.79 9.7 7.0 1 9.3 6.3 1.4 1 1 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 EGG20315.1 - 2 7.1 4.8 2.5 6.8 4.8 1.2 1 0 0 1 1 1 0 Presenilin TT_ORF1 PF02956.14 EGG20315.1 - 2.2 6.8 19.2 2.8 6.5 19.2 1.1 1 0 0 1 1 1 0 TT viral orf 1 DUF3112 PF11309.8 EGG20315.1 - 5.1 6.5 6.8 6.2 6.2 6.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) DUF4175 PF13779.6 EGG20315.1 - 8.5 4.1 7.7 10 3.9 7.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) V-ATPase_H_N PF03224.14 EGG20317.1 - 1.2e-62 212.1 0.2 2.3e-62 211.1 0.2 1.4 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EGG20317.1 - 4.3e-42 142.9 5.9 7.5e-42 142.1 3.6 2.4 2 0 0 2 2 2 1 V-ATPase subunit H Arm_2 PF04826.13 EGG20317.1 - 0.013 15.0 1.7 0.034 13.6 0.1 2.2 2 0 0 2 2 2 0 Armadillo-like Nrap_D5 PF17406.2 EGG20317.1 - 0.013 15.2 0.1 0.031 14.1 0.1 1.6 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 HEAT_2 PF13646.6 EGG20317.1 - 0.13 12.6 0.0 0.6 10.5 0.0 2.1 1 0 0 1 1 1 0 HEAT repeats p450 PF00067.22 EGG20318.1 - 2.2e-51 175.1 0.6 3e-51 174.6 0.6 1.1 1 0 0 1 1 1 1 Cytochrome P450 P16-Arc PF04699.14 EGG20318.1 - 4.6 7.7 5.7 0.7 10.4 0.4 2.4 3 1 0 3 3 3 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Ribonuclease_T2 PF00445.18 EGG20320.1 - 7.2e-47 160.0 3.9 9.3e-47 159.6 3.9 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family RVT_1 PF00078.27 EGG20321.1 - 3.6e-31 108.4 0.4 6.1e-31 107.7 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EGG20321.1 - 2.3e-16 59.6 0.0 5.8e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 EGG20321.1 - 4e-11 43.1 0.0 1.2e-10 41.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 EGG20321.1 - 4.6e-11 42.9 0.0 2e-10 40.8 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein RT_RNaseH PF17917.1 EGG20321.1 - 2.3e-08 34.3 0.0 6.2e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 EGG20321.1 - 6.4e-06 26.0 0.1 1.3e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Nup188 PF10487.9 EGG20321.1 - 0.051 11.5 0.0 0.081 10.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 zf-RVT PF13966.6 EGG20322.1 - 0.0024 18.5 0.0 0.008 16.9 0.0 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Ank_2 PF12796.7 EGG20323.1 - 0.07 13.7 0.1 0.18 12.4 0.1 1.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Xpo1 PF08389.12 EGG20324.1 - 4.9e-16 59.1 4.9 4.9e-16 59.1 4.9 5.0 4 2 0 4 4 4 2 Exportin 1-like protein TetR_C_35 PF18556.1 EGG20324.1 - 0.053 13.7 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Bacterial Tetracyclin repressor, C-terminal domain CRM1_repeat PF18777.1 EGG20324.1 - 0.29 10.7 1.7 17 5.0 0.5 2.7 2 0 0 2 2 2 0 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EGG20324.1 - 0.73 9.8 11.8 0.054 13.4 1.0 3.8 4 0 0 4 4 4 0 Importin-beta N-terminal domain DUF802 PF05650.11 EGG20324.1 - 1.2 9.6 3.8 2.8 8.5 3.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF802) Big_11 PF18200.1 EGG20325.1 - 0.25 11.3 3.7 4.8 7.2 0.2 3.9 3 0 0 3 3 3 0 Bacterial Ig-like domain Cofilin_ADF PF00241.20 EGG20327.1 - 1.3e-15 57.2 0.0 3.6e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 EGG20327.1 - 1.1e-11 44.2 0.2 2.6e-11 43.0 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGG20327.1 - 3.9e-07 29.8 0.2 1.3e-06 28.1 0.2 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGG20327.1 - 1.6e-05 24.5 0.0 4.4e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Phage_holin_3_6 PF07332.11 EGG20327.1 - 0.22 11.6 0.4 1.4 9.0 0.1 2.4 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1906 PF08924.11 EGG20328.1 - 0.055 13.6 0.3 0.079 13.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) DsbB PF02600.16 EGG20328.1 - 0.098 13.1 0.0 1.6 9.1 0.0 2.1 2 1 0 2 2 2 0 Disulfide bond formation protein DsbB Ank_5 PF13857.6 EGG20329.1 - 1.8e-06 28.1 0.4 0.46 10.9 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG20329.1 - 5.4e-05 23.7 3.7 0.028 15.0 0.0 3.8 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG20329.1 - 0.017 15.7 0.1 3.8 8.2 0.0 3.5 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG20329.1 - 0.026 15.0 0.2 1.5e+02 3.5 0.0 4.4 3 0 0 3 3 3 0 Ankyrin repeat DUF4119 PF13494.6 EGG20329.1 - 0.95 9.6 5.0 4.8 7.4 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) Ank_2 PF12796.7 EGG20331.1 - 0.0016 19.0 0.2 0.78 10.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG20331.1 - 0.017 15.6 0.1 4.9 8.1 0.0 3.9 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 EGG20331.1 - 0.073 13.4 0.2 1.3 9.4 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DUSP PF06337.12 EGG20331.1 - 0.097 13.3 1.1 1 10.0 0.6 2.8 2 0 0 2 2 2 0 DUSP domain Mito_carr PF00153.27 EGG20332.1 - 2.2e-51 171.7 6.6 5.6e-20 71.1 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein ydhR PF08803.11 EGG20332.1 - 7e-34 115.6 0.0 2e-33 114.1 0.0 1.8 1 0 0 1 1 1 1 Putative mono-oxygenase ydhR SUIM_assoc PF16619.5 EGG20332.1 - 0.035 14.2 0.3 0.035 14.2 0.3 3.5 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF789 PF05623.12 EGG20332.1 - 0.035 13.8 0.1 0.035 13.8 0.1 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF789) Spt20 PF12090.8 EGG20332.1 - 0.075 12.6 0.1 0.075 12.6 0.1 3.4 3 0 0 3 3 3 0 Spt20 family DUF2681 PF10883.8 EGG20332.1 - 9.2 6.8 19.2 9.4 6.7 9.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) PP2C PF00481.21 EGG20333.1 - 1e-49 169.5 0.0 5.7e-36 124.5 0.0 3.4 2 1 0 2 2 2 2 Protein phosphatase 2C FA_hydroxylase PF04116.13 EGG20334.1 - 9.4e-19 68.1 17.7 9.4e-19 68.1 17.7 3.6 3 1 1 4 4 3 1 Fatty acid hydroxylase superfamily Membralin PF09746.9 EGG20334.1 - 1.8e-06 27.3 3.1 1.8e-06 27.3 3.1 2.9 2 1 0 2 2 2 1 Tumour-associated protein RPA43_OB PF17875.1 EGG20334.1 - 0.0013 19.3 0.7 0.0027 18.3 0.1 1.8 2 0 0 2 2 1 1 RPA43 OB domain in RNA Pol I SDA1 PF05285.12 EGG20334.1 - 0.0019 17.7 3.1 0.0027 17.2 3.1 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 EGG20334.1 - 0.0097 14.2 6.0 0.013 13.7 6.0 1.1 1 0 0 1 1 1 1 Nop14-like family EOS1 PF12326.8 EGG20334.1 - 0.018 15.0 0.1 0.057 13.3 0.0 1.8 2 0 0 2 2 2 0 N-glycosylation protein Pex24p PF06398.11 EGG20334.1 - 0.018 14.0 0.4 0.063 12.3 0.3 2.0 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin FAM176 PF14851.6 EGG20334.1 - 0.043 13.5 3.3 0.11 12.1 3.3 1.7 1 0 0 1 1 1 0 FAM176 family FAM60A PF15396.6 EGG20334.1 - 0.055 13.5 1.7 0.092 12.7 1.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A E7 PF00527.18 EGG20334.1 - 0.18 12.1 4.2 0.76 10.0 4.0 2.2 2 0 0 2 2 2 0 E7 protein, Early protein EIIBC-GUT_N PF03612.14 EGG20334.1 - 0.19 11.5 3.7 0.32 10.7 3.7 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CPSF100_C PF13299.6 EGG20334.1 - 0.29 11.3 3.9 0.63 10.2 3.9 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PBP1_TM PF14812.6 EGG20334.1 - 0.39 11.1 3.6 0.98 9.8 3.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PI3K_1B_p101 PF10486.9 EGG20334.1 - 0.61 7.8 3.6 0.89 7.3 3.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sigma70_ner PF04546.13 EGG20334.1 - 0.77 9.6 12.3 1.3 8.8 12.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Cnd2 PF05786.14 EGG20334.1 - 2.1 6.9 7.5 3.1 6.4 7.5 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF3464 PF11947.8 EGG20334.1 - 2.3 8.0 4.4 2 8.1 0.5 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Roughex PF06020.11 EGG20334.1 - 2.4 7.2 8.0 3.9 6.5 8.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein RXT2_N PF08595.11 EGG20334.1 - 3.3 7.7 10.5 2.3 8.3 8.3 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 EGG20334.1 - 6.7 7.2 12.1 2 8.8 8.3 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SR-25 PF10500.9 EGG20335.1 - 8e-05 22.4 68.3 0.024 14.2 9.8 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein AAA_16 PF13191.6 EGG20336.1 - 2.4e-07 31.3 0.0 0.036 14.4 0.0 4.6 4 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EGG20336.1 - 1.3e-05 25.5 2.6 4.9 7.4 0.0 5.0 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 EGG20336.1 - 0.00089 19.7 8.6 2.6 8.5 0.0 5.7 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGG20336.1 - 0.0036 16.9 8.7 5.8 6.4 0.1 5.1 5 1 0 5 5 5 3 P-loop containing dynein motor region AAA_29 PF13555.6 EGG20336.1 - 0.055 13.2 1.3 1.2 9.0 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain T2SSE PF00437.20 EGG20336.1 - 0.13 11.3 1.0 19 4.2 0.0 3.2 3 0 0 3 3 3 0 Type II/IV secretion system protein SR-25 PF10500.9 EGG20336.1 - 5.7 6.5 21.7 0.012 15.3 10.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sox_N PF12444.8 EGG20336.1 - 9.8 7.4 8.1 43 5.3 8.1 2.1 1 0 0 1 1 1 0 Sox developmental protein N terminal Aldedh PF00171.22 EGG20337.1 - 4.9e-165 549.5 0.0 6.2e-165 549.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ank_2 PF12796.7 EGG20337.1 - 8.2e-17 61.6 4.5 1.9e-06 28.4 0.7 4.7 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG20337.1 - 1.5e-14 54.1 8.6 0.0014 19.2 0.0 7.2 5 2 3 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG20337.1 - 9.5e-11 41.0 2.6 1.5 9.6 0.0 7.8 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 EGG20337.1 - 5.8e-08 32.9 7.0 2.7 8.4 0.1 6.7 2 2 3 6 6 6 4 Ankyrin repeats (many copies) DUF1487 PF07368.11 EGG20337.1 - 0.0031 17.0 0.0 0.0077 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) Ank PF00023.30 EGG20337.1 - 0.019 15.4 0.9 71 4.1 0.0 5.1 4 1 1 5 5 5 0 Ankyrin repeat Acetyltransf_1 PF00583.25 EGG20338.1 - 7.1e-13 48.8 0.1 9.5e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG20338.1 - 4.8e-11 42.9 0.2 8.2e-11 42.2 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG20338.1 - 4.3e-09 36.4 0.1 6e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RRG8 PF17068.5 EGG20338.1 - 0.013 15.0 0.1 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial AstA PF04958.12 EGG20338.1 - 0.19 10.3 0.1 0.28 9.7 0.1 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Epimerase PF01370.21 EGG20339.1 - 9.4e-26 90.7 0.1 1.2e-25 90.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGG20339.1 - 4.5e-15 56.0 0.1 1e-14 54.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGG20339.1 - 2e-14 53.7 0.0 2.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGG20339.1 - 8.8e-14 51.2 0.2 4.7e-13 48.8 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGG20339.1 - 3.8e-10 39.3 0.2 7.1e-10 38.5 0.2 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EGG20339.1 - 0.00036 20.1 1.1 0.00062 19.4 1.1 1.4 1 0 0 1 1 1 1 NmrA-like family DnaB PF00772.21 EGG20339.1 - 0.0024 17.9 0.1 0.36 10.9 0.0 2.4 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain Polysacc_synt_2 PF02719.15 EGG20339.1 - 0.0065 15.6 0.2 0.0094 15.1 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGG20339.1 - 0.0073 15.5 1.5 0.093 11.9 1.5 2.5 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EGG20339.1 - 0.065 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 KR domain PX PF00787.24 EGG20340.1 - 2.4e-18 66.2 2.6 3.4e-18 65.7 2.6 1.2 1 0 0 1 1 1 1 PX domain AAA_22 PF13401.6 EGG20341.1 - 2.3e-07 31.2 0.6 4.4 7.6 0.0 5.2 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.6 EGG20341.1 - 4.5e-06 27.2 3.9 0.031 14.6 0.0 5.6 7 0 0 7 7 7 1 AAA ATPase domain AAA_7 PF12775.7 EGG20341.1 - 0.00059 19.4 7.9 4.9 6.6 0.0 5.6 5 1 0 5 5 5 3 P-loop containing dynein motor region AAA_29 PF13555.6 EGG20341.1 - 0.093 12.5 1.4 2.3 8.0 0.0 3.4 4 0 0 4 4 4 0 P-loop containing region of AAA domain AAA PF00004.29 EGG20341.1 - 0.099 13.1 10.3 11 6.5 0.0 5.3 5 0 0 5 5 5 0 ATPase family associated with various cellular activities (AAA) SET PF00856.28 EGG20341.1 - 0.36 11.2 9.3 0.11 12.8 0.3 3.4 2 0 0 2 2 2 0 SET domain DDHD PF02862.17 EGG20341.1 - 5.7 7.0 14.6 25 4.9 0.5 3.2 2 0 0 2 2 2 0 DDHD domain Ank_2 PF12796.7 EGG20342.1 - 5.7e-15 55.7 8.3 5.6e-07 30.1 0.1 5.2 3 2 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG20342.1 - 3.8e-09 36.0 7.9 1.4 9.7 0.0 8.0 8 1 1 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 EGG20342.1 - 2.5e-08 34.0 3.3 1.3 9.5 0.0 6.9 7 1 1 8 8 8 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG20342.1 - 2.6e-07 31.0 6.2 0.0034 17.9 0.0 7.0 5 2 1 6 6 6 1 Ankyrin repeats (many copies) DUF1294 PF06961.13 EGG20343.1 - 1.1e-19 70.4 0.6 1.1e-19 70.4 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1294) DUF3482 PF11981.8 EGG20343.1 - 0.0014 18.1 1.2 0.0018 17.7 0.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3482) Macoilin PF09726.9 EGG20343.1 - 0.01 14.5 15.8 0.01 14.4 15.8 1.1 1 0 0 1 1 1 1 Macoilin family ALMT PF11744.8 EGG20343.1 - 1.1 8.0 15.7 1.4 7.7 15.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Band_3_cyto PF07565.13 EGG20343.1 - 3.6 7.3 11.6 5.2 6.8 11.6 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain GGDEF PF00990.21 EGG20344.1 - 8.8e-36 123.1 0.8 1.5e-35 122.3 0.8 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Guanylate_cyc PF00211.20 EGG20344.1 - 0.0025 17.5 0.1 0.0046 16.6 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain WWE PF02825.20 EGG20344.1 - 0.97 10.1 2.8 4.3 8.0 0.1 3.2 3 0 0 3 3 3 0 WWE domain DDE_1 PF03184.19 EGG20345.1 - 1.9e-09 37.4 2.6 2e-09 37.3 0.8 2.0 2 1 0 2 2 2 1 DDE superfamily endonuclease GAPES2 PF17156.4 EGG20348.1 - 0.044 13.5 0.3 0.047 13.5 0.3 1.1 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain GGDEF PF00990.21 EGG20349.1 - 1.2e-35 122.7 0.6 2e-35 121.9 0.6 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Guanylate_cyc PF00211.20 EGG20349.1 - 0.0025 17.4 0.1 0.0044 16.7 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Arv1 PF04161.13 EGG20350.1 - 1.8e-52 178.6 5.5 4.6e-52 177.2 5.5 1.8 1 0 0 1 1 1 1 Arv1-like family Ank_2 PF12796.7 EGG20350.1 - 0.0056 17.2 0.2 0.11 13.1 0.1 3.1 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) DZR PF12773.7 EGG20350.1 - 0.11 12.6 0.2 0.24 11.5 0.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon Glutaredoxin PF00462.24 EGG20351.1 - 3.4e-18 65.6 0.0 5e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 EGG20351.1 - 0.095 12.9 0.1 0.52 10.5 0.0 2.0 1 1 1 2 2 2 0 SH3-binding, glutamic acid-rich protein OPT PF03169.15 EGG20352.1 - 7.5e-113 378.3 33.7 2.4e-109 366.7 26.1 2.2 2 0 0 2 2 2 2 OPT oligopeptide transporter protein DUF3093 PF11292.8 EGG20352.1 - 0.013 15.8 1.3 0.013 15.8 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) PsaM PF07465.13 EGG20352.1 - 0.091 12.5 6.2 0.026 14.2 2.3 2.2 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) Pkinase_Tyr PF07714.17 EGG20354.1 - 3e-42 144.7 0.0 1e-41 143.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGG20354.1 - 1.3e-38 132.9 0.0 6.1e-38 130.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Arm PF00514.23 EGG20354.1 - 4.5e-14 51.9 6.4 0.053 13.6 0.0 8.0 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat LRR_4 PF12799.7 EGG20354.1 - 4.3e-06 27.0 30.6 0.00092 19.6 5.6 6.4 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG20354.1 - 5.9e-06 25.9 27.3 0.013 15.2 4.7 5.5 3 1 2 5 5 5 3 Leucine rich repeat Kinase-like PF14531.6 EGG20354.1 - 0.00042 19.7 0.1 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like DUF913 PF06025.12 EGG20354.1 - 0.24 10.3 13.1 0.089 11.8 0.3 4.1 4 0 0 4 4 4 0 Domain of Unknown Function (DUF913) T3SchapCesA PF11439.8 EGG20354.1 - 0.26 11.4 2.9 0.25 11.5 0.4 2.3 2 1 0 2 2 2 0 Type III secretion system filament chaperone CesA LRR_6 PF13516.6 EGG20354.1 - 0.67 10.2 9.1 7.2 6.9 1.3 4.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 EGG20354.1 - 0.76 10.6 16.1 16 6.5 0.4 6.5 6 0 0 6 6 6 0 Leucine Rich Repeat PalH PF08733.10 EGG20356.1 - 0.28 10.2 1.3 0.57 9.1 1.3 1.4 1 0 0 1 1 1 0 PalH/RIM21 TFIIA PF03153.13 EGG20356.1 - 1.8 8.5 28.8 2.6 8.0 28.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kelch_6 PF13964.6 EGG20357.1 - 3e-38 128.9 13.3 3.8e-08 33.3 0.4 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EGG20357.1 - 1.1e-33 114.7 12.6 7e-08 32.3 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGG20357.1 - 8.7e-31 105.7 17.9 3.1e-08 33.5 0.3 6.6 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGG20357.1 - 1.3e-28 98.7 23.3 1.3e-09 38.1 0.0 6.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EGG20357.1 - 5.1e-28 96.4 12.4 1.2e-07 31.2 0.1 6.1 6 1 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGG20357.1 - 2.4e-25 87.5 14.5 2e-06 27.6 0.2 6.3 6 0 0 6 6 6 5 Kelch motif SAM_2 PF07647.17 EGG20357.1 - 5.8e-13 48.7 0.2 1.2e-12 47.7 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGG20357.1 - 4.1e-12 46.4 0.1 8e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Fz PF01392.22 EGG20358.1 - 6.4e-05 23.5 2.6 0.00016 22.3 2.6 1.7 1 0 0 1 1 1 1 Fz domain ECSCR PF15820.5 EGG20358.1 - 0.045 13.6 0.3 17 5.3 0.0 3.8 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator MPM1 PF17234.2 EGG20359.1 - 0.0001 22.6 3.5 0.0001 22.6 3.5 3.1 3 1 0 3 3 3 1 Mitochondrial peculiar membrane protein 1 PRIMA1 PF16101.5 EGG20359.1 - 0.0017 18.4 2.6 0.0049 16.9 2.6 1.8 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 SOG2 PF10428.9 EGG20359.1 - 8.7 5.4 22.3 6.8 5.8 21.0 1.3 1 1 0 1 1 1 0 RAM signalling pathway protein FNIP PF05725.12 EGG20360.1 - 0.37 11.0 13.3 0.87 9.8 0.5 5.8 4 3 0 4 4 4 0 FNIP Repeat Brix PF04427.18 EGG20361.1 - 1.4e-27 97.1 1.9 1.4e-27 97.1 1.9 1.5 2 0 0 2 2 2 1 Brix domain DUF2415 PF10313.9 EGG20361.1 - 0.013 15.4 0.0 0.037 13.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Mgr1 PF08602.10 EGG20361.1 - 0.044 12.6 0.7 0.064 12.1 0.7 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit WD40 PF00400.32 EGG20362.1 - 1.7e-24 85.6 6.0 0.00021 22.0 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.14 EGG20362.1 - 9.6e-21 73.9 7.1 1.8e-20 73.0 7.1 1.5 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 EGG20362.1 - 2.3e-05 24.6 0.1 0.63 10.4 0.0 4.2 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGG20362.1 - 0.00045 20.2 0.1 1.1 9.3 0.0 3.6 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Nebulin PF00880.18 EGG20362.1 - 0.51 10.3 2.6 1.6 8.7 2.6 1.8 1 0 0 1 1 1 0 Nebulin repeat DnaJ PF00226.31 EGG20363.1 - 1.3e-17 63.7 0.1 2.2e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3439 PF11921.8 EGG20364.1 - 8.3 6.4 10.8 0.54 10.2 4.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Vps52 PF04129.12 EGG20365.1 - 4.7e-94 315.9 13.9 1.1e-93 314.7 13.9 1.6 1 0 0 1 1 1 1 Vps52 / Sac2 family TPR_2 PF07719.17 EGG20365.1 - 8.4e-21 72.4 13.3 1.1e-06 28.3 1.0 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGG20365.1 - 1.4e-20 72.2 12.8 5.4e-08 32.3 0.8 7.7 8 0 0 8 8 7 5 Tetratricopeptide repeat DnaJ PF00226.31 EGG20365.1 - 2.2e-20 72.5 2.8 2.2e-20 72.5 2.8 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.6 EGG20365.1 - 4.5e-16 58.2 10.1 0.0012 18.5 0.0 6.9 5 2 2 7 7 7 4 TPR repeat TPR_16 PF13432.6 EGG20365.1 - 5.4e-16 59.0 0.0 0.043 14.5 0.2 5.8 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGG20365.1 - 6.1e-16 58.7 4.7 2.7e-05 24.6 0.0 6.4 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGG20365.1 - 1.2e-13 50.6 0.8 0.00063 20.3 0.0 6.3 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG20365.1 - 1.4e-09 37.4 12.7 0.13 12.6 0.2 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGG20365.1 - 4.2e-09 36.4 0.0 0.0017 18.5 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG20365.1 - 1e-07 31.9 8.9 0.0043 17.3 0.2 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG20365.1 - 1.1e-07 32.0 4.5 0.021 15.0 0.0 5.2 3 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGG20365.1 - 0.00014 22.1 6.5 0.46 10.8 0.4 4.7 4 2 1 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGG20365.1 - 0.00019 20.8 0.4 5.6 6.1 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG20365.1 - 0.00057 20.4 9.5 0.084 13.6 0.4 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGG20365.1 - 0.0013 19.0 10.9 0.015 15.7 0.2 5.5 4 2 2 6 6 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG20365.1 - 0.0024 17.9 1.4 2.9 8.0 0.1 3.9 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EGG20365.1 - 0.0048 16.8 1.5 3.2 8.0 0.2 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGG20365.1 - 0.026 15.0 0.5 19 5.7 0.0 3.7 2 1 1 3 3 2 0 Alkyl sulfatase dimerisation DUF3856 PF12968.7 EGG20365.1 - 0.057 13.5 1.0 59 3.7 0.0 4.3 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) DUF357 PF04010.13 EGG20365.1 - 1.9 8.7 3.8 3.8 7.7 0.7 3.2 4 0 0 4 4 2 0 Protein of unknown function (DUF357) TPR_1 PF00515.28 EGG20366.1 - 5.1e-23 79.9 15.4 4.6e-08 32.5 0.8 8.5 9 0 0 9 9 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGG20366.1 - 1e-21 75.2 14.7 9.2e-07 28.5 1.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat DnaJ PF00226.31 EGG20366.1 - 1.9e-20 72.7 2.8 1.9e-20 72.7 2.8 2.8 3 0 0 3 3 2 1 DnaJ domain TPR_16 PF13432.6 EGG20366.1 - 1.7e-19 70.1 0.1 0.0028 18.3 0.0 6.0 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGG20366.1 - 4.1e-18 65.6 6.1 0.012 16.1 0.0 6.6 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGG20366.1 - 1.1e-17 63.5 9.4 0.001 18.7 0.0 7.5 5 2 2 7 7 7 4 TPR repeat TPR_14 PF13428.6 EGG20366.1 - 1.3e-14 53.6 1.1 0.00044 20.8 0.0 6.0 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG20366.1 - 9e-11 41.1 12.9 0.11 12.8 0.2 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGG20366.1 - 8.7e-10 38.3 9.5 0.0036 17.6 0.2 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGG20366.1 - 2.3e-09 37.3 0.0 0.0013 18.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG20366.1 - 4.4e-08 33.2 6.1 0.0018 18.5 0.0 4.8 2 2 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Ank_2 PF12796.7 EGG20366.1 - 5.7e-07 30.0 1.0 1 10.0 0.0 5.2 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) TPR_12 PF13424.6 EGG20366.1 - 1.7e-05 25.0 6.1 0.4 11.0 0.3 5.3 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGG20366.1 - 2.7e-05 23.5 0.7 2.8 7.1 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG20366.1 - 4.2e-05 23.9 11.1 0.072 13.8 0.4 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGG20366.1 - 0.00026 21.2 11.0 0.0085 16.4 0.2 5.1 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG20366.1 - 0.00079 19.3 1.1 2.7 8.2 0.2 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat Ank_4 PF13637.6 EGG20366.1 - 0.00095 19.7 0.5 1.8 9.2 0.0 4.9 6 0 0 6 6 4 1 Ankyrin repeats (many copies) Fis1_TPR_C PF14853.6 EGG20366.1 - 0.0015 18.6 1.7 2.5 8.2 0.1 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat DUF3447 PF11929.8 EGG20366.1 - 0.021 14.8 18.0 3.2 7.8 0.0 6.7 4 2 2 6 6 6 0 Domain of unknown function (DUF3447) Alkyl_sulf_dimr PF14863.6 EGG20366.1 - 0.022 15.2 0.8 18 5.7 0.1 3.8 2 1 1 3 3 2 0 Alkyl sulfatase dimerisation DUF3856 PF12968.7 EGG20366.1 - 0.035 14.2 0.9 47 4.0 0.0 4.5 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) BTAD PF03704.17 EGG20366.1 - 0.044 14.2 0.1 7.9 6.9 0.0 3.2 3 1 1 4 4 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 EGG20366.1 - 0.41 10.6 1.4 25 4.9 0.2 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF357 PF04010.13 EGG20366.1 - 4 7.6 5.0 3.3 7.8 0.7 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF357) DUF3447 PF11929.8 EGG20367.1 - 0.0092 15.9 19.8 2.4 8.2 0.1 7.1 4 3 2 6 6 6 2 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EGG20367.1 - 0.011 16.3 0.2 17 6.1 0.0 5.0 5 0 0 5 5 5 0 Ankyrin repeats (many copies) SUIM_assoc PF16619.5 EGG20367.1 - 0.02 15.0 5.7 0.39 10.8 4.6 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Chlam_vir PF05475.11 EGG20367.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Pgp3 C-terminal domain Serpentine_r_xa PF03383.15 EGG20368.1 - 0.12 12.4 8.2 0.92 9.5 5.0 2.4 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa DUF2975 PF11188.8 EGG20368.1 - 1.7 8.5 10.0 0.39 10.6 1.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF1279 PF06916.13 EGG20369.1 - 2.8e-18 66.2 0.2 6.2e-18 65.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Thg1C PF14413.6 EGG20369.1 - 0.012 15.8 4.3 0.019 15.1 4.3 1.4 1 0 0 1 1 1 0 Thg1 C terminal domain EIIBC-GUT_N PF03612.14 EGG20369.1 - 0.1 12.3 0.4 0.15 11.8 0.4 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ATP-sulfurylase PF01747.17 EGG20370.1 - 1e-84 283.3 0.0 1.4e-84 282.9 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EGG20370.1 - 1.4e-61 207.0 0.0 2.2e-61 206.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EGG20370.1 - 1.2e-47 161.5 0.0 1.8e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 PUA-like domain AAA_29 PF13555.6 EGG20370.1 - 0.00023 20.8 0.0 0.00047 19.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EGG20370.1 - 0.0013 19.3 0.0 0.0024 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EGG20370.1 - 0.0026 17.8 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EGG20370.1 - 0.0051 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG20370.1 - 0.0057 17.0 0.1 0.01 16.2 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EGG20370.1 - 0.0068 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 EGG20370.1 - 0.012 15.0 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MeaB PF03308.16 EGG20370.1 - 0.024 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 EGG20370.1 - 0.038 14.3 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGG20370.1 - 0.059 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 EGG20370.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 EGG20370.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGG20370.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 EGG20370.1 - 0.16 11.4 0.1 0.51 9.7 0.0 1.8 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase CPT PF07931.12 EGG20370.1 - 0.17 11.7 0.0 3.4 7.5 0.1 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 EGG20370.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGG20370.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CLP1_P PF16575.5 EGG20370.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF4834 PF16118.5 EGG20372.1 - 0.023 15.6 1.6 0.023 15.6 1.6 4.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4834) DUF3899 PF13038.6 EGG20372.1 - 0.054 14.0 0.1 0.054 14.0 0.1 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF3899) DUF5305 PF17231.2 EGG20372.1 - 0.064 12.6 0.2 0.064 12.6 0.2 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5305) DUF4064 PF13273.6 EGG20372.1 - 0.82 10.0 2.9 4.1 7.7 2.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) MAD PF05557.13 EGG20372.1 - 0.84 7.9 35.3 0.65 8.3 10.8 2.2 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF4449 PF14613.6 EGG20372.1 - 2.5 8.2 26.0 4.2 7.5 7.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Mcm10 PF09332.11 EGG20372.1 - 4 6.8 27.2 0.56 9.6 13.4 2.1 2 0 0 2 2 2 0 Mcm10 replication factor LMBR1 PF04791.16 EGG20372.1 - 5.7 5.7 13.5 8.1 5.2 13.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein UMP1 PF05348.11 EGG20373.1 - 2.5e-21 76.1 0.1 3e-21 75.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 RRM_1 PF00076.22 EGG20374.1 - 2.6e-36 123.2 3.8 5.6e-20 70.9 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG20374.1 - 8.1e-07 29.1 0.3 0.0016 18.5 0.0 3.0 2 2 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 EGG20374.1 - 2.5e-06 27.1 0.0 3.5e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EGG20374.1 - 0.00015 22.0 0.3 1.7 8.8 0.0 3.1 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter PAP1 PF08601.10 EGG20374.1 - 0.0032 17.3 8.5 0.004 16.9 8.5 1.2 1 0 0 1 1 1 1 Transcription factor PAP1 OB_RNB PF08206.11 EGG20374.1 - 0.0051 16.5 0.0 3.8 7.3 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_occluded PF16842.5 EGG20374.1 - 0.01 15.7 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif DbpA PF03880.15 EGG20374.1 - 0.013 15.5 0.4 0.052 13.6 0.0 2.0 2 0 0 2 2 2 0 DbpA RNA binding domain DUF1866 PF08952.11 EGG20374.1 - 0.054 13.3 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) CSD PF00313.22 EGG20374.1 - 0.13 12.1 0.2 20 5.1 0.1 2.5 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain SR-25 PF10500.9 EGG20374.1 - 0.76 9.3 18.5 0.99 9.0 17.0 1.8 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein SPX PF03105.19 EGG20374.1 - 2.6 7.9 16.2 3.5 7.4 16.2 1.1 1 0 0 1 1 1 0 SPX domain GDI PF00996.18 EGG20375.1 - 7.5e-53 179.6 3.9 2.5e-37 128.4 0.6 3.1 2 1 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EGG20375.1 - 0.035 14.3 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CENP-B_dimeris PF09026.10 EGG20375.1 - 0.43 11.0 0.1 0.43 11.0 0.1 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Rhomboid_N PF12122.8 EGG20375.1 - 1.2 9.3 3.8 17 5.6 0.1 2.6 2 0 0 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease HEPN_AbiU2 PF18734.1 EGG20375.1 - 1.9 8.0 7.7 4.9 6.6 1.9 2.4 2 0 0 2 2 2 0 AbiU2 Connexin PF00029.19 EGG20375.1 - 2.3 7.9 6.7 10 5.8 1.5 2.5 2 0 0 2 2 2 0 Connexin E1_dh PF00676.20 EGG20376.1 - 2.6e-99 331.9 0.2 3.2e-99 331.7 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EGG20376.1 - 0.00067 18.9 0.0 0.0056 15.9 0.0 2.4 3 0 0 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase EF-G-binding_N PF07299.11 EGG20376.1 - 0.075 13.6 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal TPP_enzyme_C PF02775.21 EGG20376.1 - 0.13 12.0 0.6 0.73 9.6 0.1 2.3 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain eIF-5a PF01287.20 EGG20377.1 - 7.4e-17 61.2 0.3 1.1e-16 60.6 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold WD40 PF00400.32 EGG20378.1 - 9.8e-15 54.7 14.2 4.9e-05 24.0 0.2 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG20378.1 - 0.0002 21.6 0.0 4.4 7.7 0.0 4.7 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG20378.1 - 0.011 14.8 0.1 0.049 12.6 0.0 2.1 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EGG20378.1 - 0.064 11.6 0.1 0.84 7.9 0.0 2.3 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_B558a PF05038.13 EGG20378.1 - 0.77 9.3 6.2 0.37 10.3 0.3 2.7 3 0 0 3 3 3 0 Cytochrome Cytochrome b558 alpha-subunit Ebola_NP PF05505.12 EGG20378.1 - 1.1 7.5 13.3 1.9 6.7 13.3 1.4 1 0 0 1 1 1 0 Ebola nucleoprotein Tom22 PF04281.13 EGG20378.1 - 9.8 6.0 17.2 6.1 6.6 4.2 2.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 COMM_domain PF07258.14 EGG20379.1 - 7.9e-18 64.3 1.5 2.8e-17 62.6 0.6 1.9 2 0 0 2 2 2 1 COMM domain tRNA-synt_2c PF01411.19 EGG20380.1 - 1.4e-170 568.5 0.0 2.2e-170 567.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EGG20380.1 - 2.1e-17 63.0 0.7 4.5e-17 61.9 0.7 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EGG20380.1 - 0.0066 16.9 12.7 0.016 15.6 0.5 3.9 4 0 0 4 4 4 2 DHHA1 domain Nucleoporin2 PF04096.14 EGG20380.1 - 0.23 11.6 2.2 0.58 10.3 2.2 1.6 1 0 0 1 1 1 0 Nucleoporin autopeptidase EGF_2 PF07974.13 EGG20381.1 - 0.0069 16.7 11.3 0.013 15.8 11.3 1.5 1 0 0 1 1 1 1 EGF-like domain LapA_dom PF06305.11 EGG20381.1 - 0.038 13.8 0.2 0.096 12.5 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain GNVR PF13807.6 EGG20381.1 - 0.16 11.9 0.0 8.7 6.3 0.0 2.7 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase EGF_Tenascin PF18720.1 EGG20381.1 - 0.84 9.8 11.8 1.8 8.7 11.8 1.6 1 0 0 1 1 1 0 Tenascin EGF domain hEGF PF12661.7 EGG20381.1 - 2.1 9.1 5.2 6.9 7.5 5.2 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF Ammonium_transp PF00909.21 EGG20382.1 - 4e-55 187.1 18.1 6.9e-55 186.3 18.1 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family 7tm_3 PF00003.22 EGG20382.1 - 0.0013 18.5 4.4 0.016 14.9 4.4 2.3 1 1 1 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR CobT PF06213.12 EGG20382.1 - 0.14 11.5 5.5 0.21 10.9 5.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 EGG20382.1 - 7.4 4.7 8.5 10 4.2 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SET PF00856.28 EGG20383.1 - 4.3e-16 59.8 0.1 4.2e-09 37.0 0.0 2.7 2 0 0 2 2 2 2 SET domain TPR_1 PF00515.28 EGG20383.1 - 9.2e-16 56.9 14.0 0.0008 19.1 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGG20383.1 - 2e-12 46.2 10.2 0.0025 17.8 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGG20383.1 - 1.2e-08 34.4 2.8 0.074 13.1 0.0 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG20383.1 - 1.6e-06 28.3 7.8 0.04 14.2 0.1 5.1 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG20383.1 - 4e-06 26.4 10.2 0.0025 17.4 0.0 5.8 5 1 0 5 5 5 1 TPR repeat TPR_8 PF13181.6 EGG20383.1 - 1.9e-05 24.5 13.1 0.75 10.2 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG20383.1 - 0.00014 21.9 0.6 0.0056 16.7 0.2 2.8 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EGG20383.1 - 0.00039 20.2 1.2 0.54 10.2 0.0 5.1 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG20383.1 - 0.0015 19.2 0.0 0.051 14.2 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG20383.1 - 0.0035 17.6 2.6 25 5.5 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGG20383.1 - 0.0035 17.8 0.4 0.13 12.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG20383.1 - 0.0076 16.4 0.0 0.91 9.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG20383.1 - 0.027 15.3 0.0 25 6.0 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Papo_T_antigen PF02380.15 EGG20383.1 - 0.029 14.5 1.6 2.1 8.5 0.6 2.8 2 0 0 2 2 2 0 T-antigen specific domain Gp58 PF07902.11 EGG20383.1 - 0.18 10.1 0.4 9.5 4.4 0.0 2.2 2 0 0 2 2 2 0 gp58-like protein SAF PF08666.12 EGG20383.1 - 0.22 12.2 0.0 71 4.1 0.0 3.6 4 0 0 4 4 4 0 SAF domain DHHC PF01529.20 EGG20384.1 - 0.00018 21.6 3.5 0.00018 21.6 3.5 2.9 2 1 1 3 3 3 2 DHHC palmitoyltransferase DUF1748 PF08520.10 EGG20385.1 - 0.027 14.4 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) zf-RING_11 PF17123.5 EGG20386.1 - 0.024 14.4 0.0 7.1 6.5 0.0 2.7 2 0 0 2 2 2 0 RING-like zinc finger SR-25 PF10500.9 EGG20386.1 - 1 8.9 4.7 2.4 7.7 4.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ILEI PF15711.5 EGG20387.1 - 4.5e-44 148.9 6.8 2.8e-09 37.3 0.1 5.4 5 0 0 5 5 5 5 Interleukin-like EMT inducer SR-25 PF10500.9 EGG20387.1 - 6.5 6.3 11.3 12 5.4 11.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ILEI PF15711.5 EGG20388.1 - 7.5e-40 135.3 5.4 4.2e-14 52.8 0.0 4.7 4 0 0 4 4 4 4 Interleukin-like EMT inducer Peptidase_C14 PF00656.22 EGG20388.1 - 3.6e-07 30.4 0.0 6.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Tim44 PF04280.15 EGG20389.1 - 8.5e-11 42.2 0.6 1.7e-10 41.1 0.6 1.5 1 1 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 EGG20389.1 - 6.6e-07 28.6 0.3 1e-06 28.0 0.3 1.3 1 0 0 1 1 1 1 MBA1-like protein TLD PF07534.16 EGG20390.1 - 1e-14 54.9 0.4 1.4e-14 54.5 0.4 1.2 1 0 0 1 1 1 1 TLD CBM49 PF09478.10 EGG20391.1 - 1.5e-11 44.5 0.2 3.2e-11 43.4 0.2 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 dCMP_cyt_deam_1 PF00383.23 EGG20391.1 - 2.9e-11 43.1 0.3 4.8e-11 42.4 0.3 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGG20391.1 - 1.2e-09 38.1 0.1 1.8e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase CBM_2 PF00553.19 EGG20391.1 - 0.062 13.6 0.4 3 8.2 0.0 2.5 2 0 0 2 2 2 0 Cellulose binding domain Bd3614-deam PF14439.6 EGG20391.1 - 0.21 11.7 0.1 6.4 6.9 0.1 2.3 1 1 1 2 2 2 0 Bd3614-like deaminase MFS_1 PF07690.16 EGG20392.1 - 3.7e-26 91.9 28.3 5.2e-14 51.9 17.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGG20392.1 - 2e-18 66.2 20.8 3.6e-18 65.3 20.9 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein PUCC PF03209.15 EGG20392.1 - 1.8e-13 50.3 6.1 9e-10 38.1 0.0 2.0 2 0 0 2 2 2 2 PUCC protein BT1 PF03092.16 EGG20392.1 - 0.00083 17.7 2.4 0.0018 16.6 0.1 2.4 3 0 0 3 3 3 1 BT1 family Tim44 PF04280.15 EGG20393.1 - 4.7e-10 39.8 0.0 9.7e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Tim44-like domain Cypo_polyhedrin PF05865.11 EGG20393.1 - 0.022 14.2 0.3 0.036 13.5 0.3 1.3 1 0 0 1 1 1 0 Cypovirus polyhedrin protein CCDC53 PF10152.9 EGG20393.1 - 0.74 10.2 6.7 1.6 9.2 6.7 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PAF PF15715.5 EGG20393.1 - 1.1 9.8 12.7 1.8 9.1 12.7 1.3 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Roughex PF06020.11 EGG20393.1 - 2.6 7.0 10.0 0.84 8.7 6.8 1.6 1 1 1 2 2 2 0 Drosophila roughex protein COX6C PF02937.15 EGG20393.1 - 7.7 6.7 5.8 19 5.5 5.8 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Neur_chan_memb PF02932.16 EGG20393.1 - 9.9 6.1 6.0 14 5.6 6.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FKBP_C PF00254.28 EGG20394.1 - 2.1e-15 56.8 0.0 5.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2726 PF10881.8 EGG20394.1 - 0.0049 16.7 0.5 0.011 15.6 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2726) DUF4101 PF13355.6 EGG20394.1 - 0.49 10.8 4.7 1.3 9.5 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4101) TPR_2 PF07719.17 EGG20394.1 - 1.6 9.1 7.6 59 4.1 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat NDUF_C2 PF06374.11 EGG20394.1 - 4.2 7.6 7.4 0.39 10.9 0.6 2.8 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) TEX19 PF15553.6 EGG20394.1 - 6.9 6.6 6.8 2.1 8.3 1.0 2.5 2 1 0 2 2 2 0 Testis-expressed protein 19 GBP PF02263.19 EGG20395.1 - 2.7e-51 174.3 0.2 5.1e-51 173.4 0.2 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGG20395.1 - 3.2e-06 26.8 23.2 8.5e-05 22.1 0.0 2.7 2 1 0 2 2 2 1 Guanylate-binding protein, C-terminal domain Tropomyosin PF00261.20 EGG20395.1 - 0.0049 16.3 19.5 0.011 15.2 19.5 1.5 1 0 0 1 1 1 1 Tropomyosin Baculo_PEP_C PF04513.12 EGG20395.1 - 0.0076 16.3 6.0 0.0076 16.3 6.0 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 EGG20395.1 - 0.067 12.7 7.9 0.14 11.7 7.9 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 EGG20395.1 - 0.21 9.0 15.8 0.3 8.6 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ALMT PF11744.8 EGG20395.1 - 0.4 9.5 11.7 0.64 8.8 11.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Atg14 PF10186.9 EGG20395.1 - 0.43 9.6 10.4 0.71 8.9 10.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DDHD PF02862.17 EGG20395.1 - 1.2 9.2 4.7 3.2 7.9 4.7 1.7 1 0 0 1 1 1 0 DDHD domain LMBR1 PF04791.16 EGG20395.1 - 1.2 8.0 5.2 1.9 7.3 5.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein LUC7 PF03194.15 EGG20395.1 - 4.2 6.9 16.5 8.4 6.0 16.5 1.4 1 0 0 1 1 1 0 LUC7 N_terminus DUF2937 PF11157.8 EGG20395.1 - 6.5 6.4 6.6 1.3e+02 2.2 6.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) HemX PF04375.14 EGG20395.1 - 8.3 5.6 15.9 15 4.8 15.9 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase FOXP-CC PF16159.5 EGG20395.1 - 8.4 7.1 10.2 1.1 10.0 2.0 3.0 1 1 0 2 2 2 0 FOXP coiled-coil domain RNB PF00773.19 EGG20396.1 - 7.1e-78 262.2 0.0 7.1e-78 262.2 0.0 2.9 4 1 0 4 4 4 1 RNB domain OB_Dis3 PF17849.1 EGG20396.1 - 2.1e-16 59.7 0.0 6e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 EGG20396.1 - 1.3e-08 34.7 0.7 1.3e-08 34.7 0.7 3.7 4 0 0 4 4 4 2 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EGG20396.1 - 0.00016 21.5 0.2 0.00016 21.5 0.2 2.5 2 0 0 2 2 2 1 S1 domain CSD2 PF17876.1 EGG20396.1 - 0.0099 16.0 0.2 0.33 11.2 0.0 3.1 2 1 0 2 2 2 1 Cold shock domain Dis3l2_C_term PF17877.1 EGG20396.1 - 0.087 13.2 0.1 0.087 13.2 0.1 3.7 3 1 1 4 4 4 0 DIS3-like exonuclease 2 C terminal AbfS_sensor PF18225.1 EGG20396.1 - 0.15 12.0 0.7 52 3.9 0.1 3.5 3 0 0 3 3 3 0 Sensor histidine kinase (AbfS) sensor domain rve PF00665.26 EGG20397.1 - 1.5e-07 31.7 0.0 2.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Ntox15 PF15604.6 EGG20397.1 - 0.13 12.4 0.3 0.4 10.8 0.2 1.8 1 1 1 2 2 2 0 Novel toxin 15 Inhibitor_I36 PF03995.13 EGG20399.1 - 3.8e-08 33.1 0.6 3.8e-08 33.1 0.6 1.4 2 0 0 2 2 2 1 Peptidase inhibitor family I36 Ceramidse_alk_C PF17048.5 EGG20399.1 - 0.0034 17.3 0.1 0.004 17.1 0.1 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Crystall PF00030.19 EGG20399.1 - 0.029 14.6 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 Beta/Gamma crystallin Pyr_redox_2 PF07992.14 EGG20400.1 - 1.6e-10 40.7 0.1 7.6e-09 35.2 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG20400.1 - 1.4e-05 24.5 0.6 0.68 9.1 0.0 4.2 3 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGG20400.1 - 0.00059 19.1 0.0 0.13 11.5 0.0 2.4 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 EGG20400.1 - 0.0037 17.3 0.0 0.042 13.8 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGG20400.1 - 0.0043 17.2 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EGG20400.1 - 0.006 17.0 0.0 0.66 10.4 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EGG20400.1 - 0.011 14.8 0.0 0.11 11.5 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein PhnA PF03831.14 EGG20400.1 - 0.018 14.9 1.0 9 6.3 0.0 3.0 3 0 0 3 3 3 0 PhnA domain DUF4756 PF15948.5 EGG20400.1 - 0.065 13.1 0.9 0.1 12.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4756) NAD_binding_1 PF00175.21 EGG20401.1 - 2.3e-14 53.9 0.0 4.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGG20401.1 - 1.7e-08 34.7 0.0 3.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 EGG20401.1 - 1.1e-05 26.0 0.1 4.6e-05 23.9 0.0 2.2 3 0 0 3 3 3 1 Globin NAD_binding_6 PF08030.12 EGG20401.1 - 0.00082 19.5 0.0 1 9.4 0.1 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Nop53 PF07767.11 EGG20402.1 - 1.1e-10 41.5 27.3 1.1e-10 41.5 27.3 2.3 2 1 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) CENP-B_dimeris PF09026.10 EGG20403.1 - 0.038 14.4 1.8 1.3 9.4 0.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain F-box-like PF12937.7 EGG20403.1 - 0.11 12.4 0.1 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 F-box-like FAM176 PF14851.6 EGG20403.1 - 1.3 8.6 8.6 1.3 8.7 2.7 2.2 2 0 0 2 2 2 0 FAM176 family DUF4611 PF15387.6 EGG20403.1 - 2.1 8.6 14.3 1.3 9.2 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) IF4E PF01652.18 EGG20404.1 - 2.6e-12 46.8 0.2 3.8e-12 46.3 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Arabinose_Isome PF02610.15 EGG20404.1 - 0.0059 15.9 0.0 0.0075 15.5 0.0 1.2 1 0 0 1 1 1 1 L-arabinose isomerase 2-oxoacid_dh PF00198.23 EGG20405.1 - 3.3e-82 275.4 0.2 4.3e-82 275.1 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGG20405.1 - 3.2e-21 75.0 2.2 6.6e-21 73.9 2.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGG20405.1 - 0.013 15.3 5.9 0.81 9.6 0.2 3.0 2 1 1 3 3 3 0 Biotin-lipoyl like PYNP_C PF07831.13 EGG20405.1 - 0.027 14.1 0.3 0.56 9.9 0.1 2.5 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain GCV_H PF01597.19 EGG20405.1 - 0.087 12.7 0.2 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein eIF3_subunit PF08597.10 EGG20405.1 - 0.89 9.4 10.0 1.4 8.8 10.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF3306 PF11748.8 EGG20405.1 - 1 10.2 6.5 1.8 9.5 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Mucin PF01456.17 EGG20405.1 - 5.6 7.0 8.1 0.28 11.2 2.2 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Formyl_trans_N PF00551.19 EGG20408.1 - 0.033 13.9 0.6 0.057 13.2 0.6 1.3 1 0 0 1 1 1 0 Formyl transferase Sir1 PF11603.8 EGG20408.1 - 0.042 14.3 2.3 0.042 14.3 2.3 2.9 2 2 1 3 3 3 0 Regulatory protein Sir1 cwf18 PF08315.12 EGG20410.1 - 5.7e-13 49.7 42.2 3.7e-09 37.4 36.3 3.0 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor SAP PF02037.27 EGG20410.1 - 0.038 13.8 1.9 0.12 12.2 0.3 2.6 2 0 0 2 2 2 0 SAP domain DUF3439 PF11921.8 EGG20410.1 - 0.17 11.8 1.1 0.32 10.9 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RHH_1 PF01402.21 EGG20410.1 - 0.99 9.4 0.0 0.99 9.4 0.0 3.0 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family MID_MedPIWI PF18296.1 EGG20410.1 - 7.1 6.3 19.4 3 7.6 11.9 2.3 2 0 0 2 2 2 0 MID domain of medPIWI Ammonium_transp PF00909.21 EGG20411.1 - 4e-49 167.4 14.7 1.8e-36 125.7 6.3 2.0 1 1 1 2 2 2 2 Ammonium Transporter Family Arm PF00514.23 EGG20412.1 - 1.4e-05 25.0 0.0 0.061 13.4 0.0 4.6 5 1 0 5 5 5 2 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 EGG20412.1 - 0.027 14.4 0.1 0.17 11.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) DUF1981 PF09324.10 EGG20412.1 - 0.066 13.1 0.0 1.3 9.0 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) Peptidase_S28 PF05577.12 EGG20413.1 - 5.2e-83 279.3 5.4 8e-83 278.6 5.4 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Zip PF02535.22 EGG20414.1 - 4.9e-37 127.9 6.0 4.9e-37 127.9 6.0 2.9 2 1 1 3 3 3 1 ZIP Zinc transporter DUF3464 PF11947.8 EGG20414.1 - 0.00079 19.2 0.1 0.65 9.8 0.3 3.4 3 0 0 3 3 3 1 Photosynthesis affected mutant 68 Presenilin PF01080.17 EGG20414.1 - 0.063 12.0 0.0 0.063 12.0 0.0 2.9 3 1 1 4 4 4 0 Presenilin Velvet PF11754.8 EGG20414.1 - 0.099 12.6 3.7 0.043 13.8 1.0 1.7 3 0 0 3 3 3 0 Velvet factor DUF5413 PF17434.2 EGG20414.1 - 0.24 11.7 0.1 0.24 11.7 0.1 3.8 4 1 0 4 4 4 0 Family of unknown function (DUF5413) E1-E2_ATPase PF00122.20 EGG20414.1 - 0.33 10.4 0.0 0.33 10.4 0.0 2.3 2 0 0 2 2 2 0 E1-E2 ATPase BaxI_1 PF12811.7 EGG20414.1 - 1.5 8.3 8.4 5.8 6.4 0.0 3.1 2 1 0 2 2 2 0 Bax inhibitor 1 like Pep1_7 PF17232.2 EGG20414.1 - 3.5 8.2 12.8 1.1 9.8 0.1 2.9 2 0 0 2 2 2 0 Elicitor peptide 1-7 Ribosomal_60s PF00428.19 EGG20414.1 - 4.2 8.0 5.3 21 5.8 0.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Dicty_REP PF05086.12 EGG20414.1 - 4.3 5.2 7.9 9.8 4.0 7.9 1.5 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peroxin-3 PF04882.12 EGG20414.1 - 5.1 6.0 8.1 0.047 12.7 0.5 1.5 2 0 0 2 2 1 0 Peroxin-3 Actin PF00022.19 EGG20415.1 - 6.8e-89 298.3 0.0 1.1e-87 294.4 0.0 2.1 1 1 0 1 1 1 1 Actin N-SET PF11764.8 EGG20415.1 - 0.00089 19.4 1.3 0.0015 18.6 1.3 1.3 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N Sigma70_ner PF04546.13 EGG20415.1 - 0.0081 16.1 1.5 0.062 13.2 2.9 1.7 2 0 0 2 2 2 1 Sigma-70, non-essential region Acetate_kinase PF00871.17 EGG20415.1 - 0.093 11.4 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 Acetokinase family Spore_coat_CotO PF14153.6 EGG20415.1 - 0.098 12.6 7.2 0.18 11.7 7.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO CPSF100_C PF13299.6 EGG20415.1 - 0.64 10.2 3.4 2 8.6 3.4 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FAM176 PF14851.6 EGG20415.1 - 1.6 8.4 5.1 2.9 7.6 5.1 1.3 1 0 0 1 1 1 0 FAM176 family MA3 PF02847.17 EGG20416.1 - 2.4e-24 85.5 1.6 8.9e-24 83.7 1.6 2.1 1 0 0 1 1 1 1 MA3 domain FAP PF07174.11 EGG20416.1 - 1.1 8.7 16.0 1.7 8.0 16.0 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) UCH PF00443.29 EGG20417.1 - 6.3e-75 252.0 1.7 6.3e-75 252.0 1.7 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RhoGEF PF00621.20 EGG20417.1 - 1.2e-32 113.7 1.6 4.2e-32 111.8 0.5 2.6 3 0 0 3 3 3 1 RhoGEF domain DUSP PF06337.12 EGG20417.1 - 6.1e-14 52.4 0.4 6.1e-14 52.4 0.4 4.3 4 0 0 4 4 4 1 DUSP domain Ubiquitin_3 PF14836.6 EGG20417.1 - 3.7e-07 30.0 0.0 1.1e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EGG20417.1 - 0.0032 17.2 0.4 3.2 7.6 0.1 3.2 3 0 0 3 3 3 2 Ubiquitin family ThiS PF02597.20 EGG20417.1 - 0.02 15.5 0.0 0.18 12.5 0.0 2.7 2 0 0 2 2 2 0 ThiS family TBK1_ULD PF18396.1 EGG20417.1 - 0.055 13.4 0.8 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGG20417.1 - 0.096 12.5 0.0 0.6 9.9 0.1 2.2 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain INTS5_C PF14838.6 EGG20418.1 - 4.8e-15 55.3 35.4 4.2e-14 52.1 0.2 3.4 3 1 1 4 4 4 2 Integrator complex subunit 5 C-terminus Mucin PF01456.17 EGG20418.1 - 3.9 7.5 12.6 0.092 12.7 5.4 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Abhydrolase_1 PF00561.20 EGG20420.1 - 8.7e-14 51.8 0.2 1.3e-09 38.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG20420.1 - 7.5e-07 28.6 0.0 1.8e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 SAM_2 PF07647.17 EGG20420.1 - 0.00036 20.6 0.0 0.00076 19.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Abhydrolase_6 PF12697.7 EGG20420.1 - 0.0035 18.0 0.0 0.0062 17.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 EGG20420.1 - 0.0039 16.5 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Cutinase PF01083.22 EGG20420.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Cutinase Viral_Beta_CD PF04530.12 EGG20420.1 - 0.01 16.1 0.2 0.027 14.7 0.2 1.7 1 0 0 1 1 1 0 Viral Beta C/D like family FlbT PF07378.11 EGG20420.1 - 0.023 14.8 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein FlbT Lipase_3 PF01764.25 EGG20420.1 - 0.033 14.0 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) SAM_Ste50p PF09235.10 EGG20420.1 - 0.068 13.4 0.1 0.25 11.6 0.1 2.0 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_1 PF00536.30 EGG20420.1 - 0.069 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CAP_GLY PF01302.25 EGG20422.1 - 5.5e-19 67.9 0.7 8.5e-19 67.3 0.7 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 EGG20422.1 - 1.4e-11 44.0 20.2 0.0003 20.5 0.1 5.2 4 1 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EGG20422.1 - 1.9e-11 44.0 34.5 0.00017 21.9 2.4 6.6 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGG20422.1 - 0.00018 21.0 11.3 0.029 13.9 2.2 3.6 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EGG20422.1 - 0.18 12.5 15.3 21 6.2 0.1 6.0 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EGG20422.1 - 1.2 9.3 24.5 8.5 6.7 2.2 6.6 8 0 0 8 8 8 0 Leucine Rich repeat Ras PF00071.22 EGG20423.1 - 8.3e-60 201.1 0.0 9.6e-60 200.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG20423.1 - 1.1e-20 74.0 0.0 1.5e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG20423.1 - 2.7e-09 36.7 0.0 3.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG20423.1 - 4.4e-06 26.4 0.2 3e-05 23.6 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG20423.1 - 8.4e-05 22.6 0.0 0.00013 22.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG20423.1 - 9.2e-05 22.4 0.2 0.39 10.6 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase ATP_bind_1 PF03029.17 EGG20423.1 - 0.0073 16.1 0.9 0.084 12.6 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EGG20423.1 - 0.033 13.7 0.1 0.16 11.5 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 EGG20423.1 - 0.039 13.2 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Septin ParA PF10609.9 EGG20423.1 - 0.2 11.0 0.3 0.78 9.1 0.1 1.8 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase Ac76 PF05814.11 EGG20424.1 - 1.6 8.8 5.8 6.7 6.8 1.5 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) OTU PF02338.19 EGG20425.1 - 8.2e-07 29.6 0.0 1e-05 26.0 0.0 2.2 2 0 0 2 2 2 1 OTU-like cysteine protease TBK1_ULD PF18396.1 EGG20425.1 - 0.0091 15.9 0.0 0.024 14.5 0.0 1.7 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain HNH PF01844.23 EGG20425.1 - 0.031 14.5 0.1 0.077 13.2 0.1 1.6 1 0 0 1 1 1 0 HNH endonuclease UN_NPL4 PF11543.8 EGG20425.1 - 0.034 14.6 0.5 0.74 10.3 0.0 2.4 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 zf-UBP PF02148.19 EGG20425.1 - 0.051 13.9 0.2 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein ubiquitin PF00240.23 EGG20425.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin family Glyco_hydro_9 PF00759.19 EGG20426.1 - 3.8e-100 336.2 9.9 6e-100 335.6 9.8 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 Mucin PF01456.17 EGG20426.1 - 8.6 6.4 47.8 3.6 7.6 1.0 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein BB_PF PF18063.1 EGG20427.1 - 1.1e-19 70.9 5.0 1.4e-19 70.5 5.0 1.1 1 0 0 1 1 1 1 Beta barrel Pore-forming domain eIF2_C PF09173.11 EGG20428.1 - 1.8e-34 117.9 1.2 2.8e-34 117.2 0.2 1.9 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EGG20428.1 - 2.3e-22 79.5 1.8 2.7e-21 76.0 1.8 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGG20428.1 - 6e-11 42.6 0.2 6e-11 42.6 0.2 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EGG20428.1 - 0.0035 17.3 0.3 0.055 13.4 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EGG20428.1 - 0.0042 17.2 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EGG20428.1 - 0.023 14.7 0.2 0.05 13.6 0.2 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DPBB_1 PF03330.18 EGG20430.1 - 9.7e-13 48.2 0.3 5.4e-11 42.6 0.2 2.7 2 1 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 EGG20430.1 - 0.095 12.7 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Pollen allergen TIG PF01833.24 EGG20431.1 - 2.6e-12 46.6 50.4 0.00083 19.4 5.1 7.3 7 0 0 7 7 7 6 IPT/TIG domain EGF_2 PF07974.13 EGG20431.1 - 0.001 19.4 15.0 0.0023 18.3 15.0 1.7 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 EGG20431.1 - 0.07 13.3 12.2 0.17 12.1 12.2 1.6 1 0 0 1 1 1 0 Laminin EGF domain ubiquitin PF00240.23 EGG20432.1 - 9.6e-06 25.3 0.1 1.5e-05 24.7 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGG20432.1 - 0.00012 21.8 0.2 0.00086 19.1 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGG20432.1 - 0.0013 19.1 0.0 0.0017 18.8 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain DUF5517 PF17639.2 EGG20432.1 - 0.062 13.6 0.1 0.076 13.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5517) TOBE_2 PF08402.10 EGG20432.1 - 0.14 12.3 0.0 0.91 9.7 0.0 2.0 2 0 0 2 2 2 0 TOBE domain Aminotran_5 PF00266.19 EGG20433.1 - 4.1e-10 39.2 0.0 1.6e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Skp1_POZ PF03931.15 EGG20434.1 - 4.3e-07 30.0 0.0 9.2e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 EGG20434.1 - 0.0036 17.5 0.1 0.0047 17.1 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain ssDBP_DBD PF18361.1 EGG20434.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain Mob1_phocein PF03637.17 EGG20435.1 - 1.7e-56 190.9 0.1 2e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family DUF1744 PF08490.12 EGG20436.1 - 9.8e-125 416.2 0.7 1.9e-124 415.3 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EGG20436.1 - 3.9e-71 239.9 5.1 3.9e-71 239.9 5.1 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EGG20436.1 - 1.8e-17 63.2 9.1 4.2e-13 48.8 2.2 4.3 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EGG20436.1 - 2.1e-09 37.4 0.1 8.2e-09 35.5 0.1 2.0 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EGG20436.1 - 8.1e-06 25.9 0.2 8.2e-05 22.7 0.1 2.9 3 0 0 3 3 3 1 RNase_H superfamily Cytochrome_C7 PF14522.6 EGG20436.1 - 0.023 14.7 3.0 0.13 12.3 3.0 2.4 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c NAPRTase_C PF17956.1 EGG20436.1 - 0.028 14.8 0.1 0.2 12.1 0.1 2.6 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain GBP PF02263.19 EGG20437.1 - 2e-58 197.7 6.7 3.6e-46 157.5 0.0 4.3 5 0 0 5 5 5 3 Guanylate-binding protein, N-terminal domain ATG27 PF09451.10 EGG20437.1 - 3.5e-17 63.2 0.1 9.9e-17 61.7 0.1 1.8 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 EGG20437.1 - 9.9e-10 37.9 0.4 9.9e-10 37.9 0.4 2.0 2 0 0 2 2 2 1 Mannose-6-phosphate receptor GBP_C PF02841.14 EGG20437.1 - 7e-05 22.4 13.1 0.0094 15.4 0.0 2.3 2 0 0 2 2 2 2 Guanylate-binding protein, C-terminal domain CIMR PF00878.18 EGG20437.1 - 0.054 13.6 0.3 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat Arc_C PF18162.1 EGG20437.1 - 0.11 12.4 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 Arc C-lobe GCP_C_terminal PF04130.13 EGG20437.1 - 0.13 11.7 3.1 0.25 10.8 2.2 1.9 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal UPF0242 PF06785.11 EGG20437.1 - 0.71 9.9 10.4 1.5 8.9 10.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SAP PF02037.27 EGG20438.1 - 1.2e-09 37.7 2.2 2.4e-09 36.7 2.2 1.6 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 EGG20438.1 - 5.3e-05 23.4 5.9 5.3e-05 23.4 5.9 4.7 3 1 1 5 5 5 1 RNSP1-SAP18 binding (RSB) motif SOG2 PF10428.9 EGG20438.1 - 0.0025 17.1 14.7 0.0025 17.1 14.7 2.6 2 1 0 2 2 2 1 RAM signalling pathway protein RRM_1 PF00076.22 EGG20438.1 - 0.021 14.6 0.1 0.091 12.6 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HeH PF12949.7 EGG20438.1 - 0.025 14.3 0.7 0.05 13.3 0.0 1.9 2 0 0 2 2 2 0 HeH/LEM domain SDA1 PF05285.12 EGG20438.1 - 1.5 8.1 45.7 1.7 8.0 6.7 2.5 2 0 0 2 2 2 0 SDA1 Myb_DNA-binding PF00249.31 EGG20439.1 - 9.9e-08 32.1 0.1 3.7e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain PapG_N PF03627.13 EGG20440.1 - 0.035 13.8 0.0 0.083 12.5 0.0 1.6 1 0 0 1 1 1 0 PapG carbohydrate binding domain Cullin_Nedd8 PF10557.9 EGG20440.1 - 0.11 12.6 0.4 59 3.8 0.0 4.0 4 0 0 4 4 4 0 Cullin protein neddylation domain DUF2151 PF10221.9 EGG20441.1 - 9e-09 34.5 14.5 3.9e-06 25.8 2.1 2.6 2 1 0 2 2 2 2 Cell cycle and development regulator Spt20 PF12090.8 EGG20441.1 - 0.0053 16.4 17.9 0.0053 16.4 17.9 3.5 3 1 0 3 3 3 1 Spt20 family CENP-X PF09415.10 EGG20442.1 - 4.5e-16 58.9 1.3 5.6e-16 58.6 1.3 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X NUDIX PF00293.28 EGG20445.1 - 1.9e-08 34.4 0.0 2.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Trs65 PF12735.7 EGG20446.1 - 0.00092 18.7 12.6 0.00092 18.7 12.6 4.8 2 2 0 2 2 2 1 TRAPP trafficking subunit Trs65 Syntaxin-6_N PF09177.11 EGG20446.1 - 2.9 8.5 6.3 3 8.5 0.0 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Sin_N PF04801.13 EGG20447.1 - 2.6e-85 287.2 10.5 7.6e-83 279.1 9.5 3.2 2 1 0 2 2 2 2 Sin-like protein conserved region Ras PF00071.22 EGG20448.1 - 7e-56 188.3 0.1 8.5e-56 188.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG20448.1 - 2.2e-33 115.0 0.1 3.9e-33 114.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG20448.1 - 1.8e-13 50.3 0.1 2.2e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG20448.1 - 0.0046 16.5 0.0 0.0061 16.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGG20448.1 - 0.0056 16.1 0.1 0.0086 15.5 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGG20448.1 - 0.016 15.1 0.3 1.3 8.9 0.1 2.4 2 1 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 EGG20448.1 - 0.021 14.9 0.5 0.03 14.4 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 EGG20448.1 - 0.071 13.0 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 NTPase IMS PF00817.20 EGG20449.1 - 5.1e-38 130.4 0.0 7.9e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family LRR_4 PF12799.7 EGG20450.1 - 0.044 14.2 0.0 4.2 7.9 0.0 2.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF3439 PF11921.8 EGG20451.1 - 0.094 12.7 4.4 0.15 12.1 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGG20451.1 - 2.2 6.4 8.8 2.6 6.1 8.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mem_trans PF03547.18 EGG20453.1 - 0.025 13.0 0.5 0.024 13.1 0.5 1.2 1 0 0 1 1 1 0 Membrane transport protein Rho_N PF07498.12 EGG20453.1 - 0.048 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain LRR_4 PF12799.7 EGG20454.1 - 0.061 13.8 16.6 19 5.9 2.0 6.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) FAM60A PF15396.6 EGG20454.1 - 0.092 12.7 11.2 0.23 11.5 11.2 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Rho_N PF07498.12 EGG20455.1 - 0.0026 17.7 6.3 0.0053 16.7 6.3 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain NusG_add PF18298.1 EGG20460.1 - 0.14 12.4 1.4 30 4.9 0.0 3.3 3 0 0 3 3 3 0 NusG additional domain PIEZO PF15917.5 EGG20460.1 - 0.49 9.8 17.3 0.14 11.7 5.1 2.6 2 0 0 2 2 2 0 Piezo SURF6 PF04935.12 EGG20460.1 - 0.84 9.4 30.1 1.7 8.4 11.3 2.5 2 0 0 2 2 2 0 Surfeit locus protein 6 Utp14 PF04615.13 EGG20460.1 - 5 5.6 46.2 0.7 8.4 19.0 2.1 2 0 0 2 2 2 0 Utp14 protein WD40 PF00400.32 EGG20463.1 - 2.2e-06 28.3 16.5 0.073 14.0 0.2 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG20463.1 - 0.00086 19.6 0.1 1.2 9.5 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SAM_3 PF18016.1 EGG20463.1 - 0.094 12.5 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DSPc PF00782.20 EGG20464.1 - 8.4e-32 109.8 0.0 1.2e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG20464.1 - 0.0026 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EGG20464.1 - 0.045 14.1 0.1 0.33 11.3 0.0 2.2 3 0 0 3 3 3 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 EGG20464.1 - 0.069 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DENN PF02141.21 EGG20466.1 - 1e-27 97.3 0.3 1e-27 97.3 0.3 2.8 4 0 0 4 4 4 1 DENN (AEX-3) domain uDENN PF03456.18 EGG20466.1 - 4e-06 27.5 3.6 3.2e-05 24.6 2.7 3.1 2 1 0 2 2 2 1 uDENN domain Secretin_N_2 PF07655.13 EGG20466.1 - 0.0067 16.9 10.4 0.0067 16.9 10.4 4.1 4 0 0 4 4 4 1 Secretin N-terminal domain PPDFL PF15060.6 EGG20466.1 - 0.18 12.3 2.2 0.35 11.4 0.3 2.4 2 0 0 2 2 2 0 Differentiation and proliferation regulator C2 PF00168.30 EGG20467.1 - 4.1e-22 78.4 1.6 7.4e-22 77.6 0.0 2.2 3 0 0 3 3 3 1 C2 domain PH PF00169.29 EGG20467.1 - 2.1e-12 47.5 0.5 2.1e-12 47.5 0.5 1.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EGG20467.1 - 4.4e-06 27.1 2.9 0.0007 20.0 2.9 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EGG20467.1 - 1.9e-05 24.7 0.1 3.7e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGG20467.1 - 0.019 15.2 0.2 0.039 14.2 0.2 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain HCO3_cotransp PF00955.21 EGG20468.1 - 0.042 12.7 0.4 0.074 11.9 0.4 1.4 1 0 0 1 1 1 0 HCO3- transporter family UPF0128 PF03673.13 EGG20468.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) Orf78 PF06024.12 EGG20468.1 - 0.14 12.4 2.0 0.18 12.1 0.5 2.0 2 0 0 2 2 2 0 Orf78 (ac78) HSP20 PF00011.21 EGG20469.1 - 7.7e-11 42.0 0.8 1.2e-10 41.4 0.8 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG20469.1 - 2e-05 24.0 0.0 3.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 EGG20469.1 - 0.0072 16.4 0.6 1.4 9.1 0.1 2.3 2 0 0 2 2 2 2 FKBP26_C-terminal CS PF04969.16 EGG20469.1 - 0.055 14.5 0.9 0.12 13.5 0.9 1.6 1 0 0 1 1 1 0 CS domain Peptidase_M22 PF00814.25 EGG20470.1 - 1.2e-80 271.1 0.0 1.5e-80 270.8 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Cry1Ac_D5 PF17997.1 EGG20470.1 - 0.11 12.3 0.1 15 5.4 0.0 2.2 2 0 0 2 2 2 0 Insecticidal delta-endotoxin CryIA(c) domain 5 zf-CHCC PF10276.9 EGG20471.1 - 6.3e-18 64.6 2.5 8.4e-18 64.1 2.5 1.2 1 0 0 1 1 1 1 Zinc-finger domain zf_C2H2_6 PF18450.1 EGG20471.1 - 0.12 12.1 0.6 0.2 11.4 0.6 1.4 1 0 0 1 1 1 0 Zinc Finger domain DUF448 PF04296.13 EGG20471.1 - 0.12 12.2 0.0 0.39 10.6 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF448) Pro_isomerase PF00160.21 EGG20472.1 - 7e-55 185.6 0.0 7.9e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med10 PF09748.9 EGG20473.1 - 6.9e-19 68.0 3.3 2.8e-18 66.1 2.1 2.2 1 1 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex AAA_22 PF13401.6 EGG20473.1 - 0.026 14.8 0.5 0.055 13.7 0.5 1.6 1 0 0 1 1 1 0 AAA domain UCH PF00443.29 EGG20473.1 - 1.2 8.6 6.5 2.2 7.7 6.5 1.5 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase RecG_N PF17190.4 EGG20473.1 - 1.9 9.3 8.5 0.19 12.5 1.6 2.4 2 1 0 2 2 2 0 RecG N-terminal helical domain PWWP PF00855.17 EGG20474.1 - 3.2e-10 40.3 0.1 2.4e-09 37.5 0.1 2.7 1 0 0 1 1 1 1 PWWP domain ELL PF10390.9 EGG20474.1 - 7.4e-09 35.5 3.1 2.3e-08 33.9 3.1 1.9 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL RGS PF00615.19 EGG20475.1 - 3.8e-29 101.4 2.7 4.6e-29 101.1 2.7 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain GAPES1 PF17155.4 EGG20475.1 - 0.0083 15.5 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 Gammaproteobacterial periplasmic sensor domain SapB_2 PF03489.17 EGG20476.1 - 8.3e-08 32.2 0.5 8.3e-08 32.2 0.5 3.4 4 0 0 4 4 4 1 Saposin-like type B, region 2 SapB_1 PF05184.15 EGG20476.1 - 7.7e-07 29.0 3.2 0.0003 20.7 0.0 3.9 4 0 0 4 4 4 2 Saposin-like type B, region 1 FAM199X PF15814.5 EGG20476.1 - 4.4 6.3 22.3 8.8 5.3 22.3 1.6 1 1 0 1 1 1 0 Protein family FAM199X Cullin PF00888.22 EGG20477.1 - 1.8e-151 505.8 31.0 4.1e-146 488.2 27.3 2.1 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 EGG20477.1 - 6.2e-26 90.2 2.6 1.2e-25 89.3 0.6 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain Pkinase PF00069.25 EGG20478.1 - 2.2e-43 148.5 0.0 6.2e-36 124.1 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20478.1 - 3.3e-16 59.4 0.0 2.7e-12 46.5 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGG20478.1 - 0.0042 17.0 0.0 0.007 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGG20478.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGG20478.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Ald_Xan_dh_C2 PF02738.18 EGG20479.1 - 1.7e-196 653.9 0.1 2.6e-196 653.3 0.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EGG20479.1 - 1.1e-41 142.4 0.0 2.7e-41 141.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EGG20479.1 - 8.9e-34 115.8 0.0 2.2e-33 114.5 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 EGG20479.1 - 3.6e-31 107.8 0.2 8.5e-31 106.6 0.2 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 EGG20479.1 - 6.3e-28 96.6 0.2 1.6e-27 95.3 0.2 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EGG20479.1 - 8.8e-08 32.0 1.6 1.2e-07 31.5 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 EGG20479.1 - 0.16 11.8 2.1 0.34 10.7 1.1 2.1 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Ank_2 PF12796.7 EGG20480.1 - 3.6e-26 91.6 27.8 6.4e-09 36.3 0.3 7.1 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG20480.1 - 1.1e-23 83.2 16.5 0.0001 22.8 0.0 9.4 8 1 2 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG20480.1 - 1e-13 50.1 15.0 2.4 9.0 0.0 12.7 13 1 1 14 14 14 3 Ankyrin repeat SUZ PF12752.7 EGG20480.1 - 1.9e-13 50.9 1.9 1.9e-13 50.9 1.9 3.6 4 0 0 4 4 4 1 SUZ domain Ank_5 PF13857.6 EGG20480.1 - 6.6e-10 39.1 41.0 0.013 15.8 0.0 13.3 6 3 8 14 14 14 4 Ankyrin repeats (many copies) SR-25 PF10500.9 EGG20480.1 - 0.0009 18.9 0.3 0.0009 18.9 0.3 2.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF5049 PF16468.5 EGG20480.1 - 0.0014 18.5 0.1 7.5 6.5 0.0 5.1 5 1 0 5 5 5 1 Domain of unknown function (DUF5049) SUIM_assoc PF16619.5 EGG20480.1 - 1.2 9.3 17.0 1.6 8.9 9.5 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Fib_alpha PF08702.10 EGG20481.1 - 0.023 14.9 2.8 0.036 14.2 2.8 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SPX PF03105.19 EGG20481.1 - 3.3 7.5 9.2 4.1 7.2 9.2 1.3 1 0 0 1 1 1 0 SPX domain Muted PF14942.6 EGG20482.1 - 3.7e-15 56.6 11.0 4.5e-15 56.3 11.0 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein Herpes_U59 PF04529.12 EGG20482.1 - 0.011 14.8 0.3 0.013 14.6 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus U59 protein EXOSC1 PF10447.9 EGG20482.1 - 0.03 14.9 1.4 0.042 14.4 1.3 1.4 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Sec2p PF06428.11 EGG20482.1 - 0.066 13.2 6.2 0.036 14.0 3.4 1.9 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF3813 PF12758.7 EGG20482.1 - 0.19 12.1 6.0 1.3 9.4 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3813) Ras PF00071.22 EGG20483.1 - 1.6e-59 200.1 0.1 1.8e-59 199.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG20483.1 - 2.4e-33 114.9 0.0 4.1e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG20483.1 - 8.7e-13 48.1 0.0 1.1e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG20483.1 - 3.5e-05 23.8 0.1 7.8e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG20483.1 - 0.00017 21.2 0.1 0.0066 16.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGG20483.1 - 0.0013 18.1 0.0 0.0028 17.0 0.0 1.5 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGG20483.1 - 0.0014 18.6 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 EGG20483.1 - 0.0027 17.4 0.1 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EGG20483.1 - 0.0084 15.6 0.0 0.022 14.2 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Septin PF00735.18 EGG20483.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin DNA_pol_A_exo1 PF01612.20 EGG20484.1 - 1.9e-25 89.6 0.6 5.9e-25 88.0 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease Tctex-1 PF03645.13 EGG20484.1 - 0.094 13.0 1.5 0.21 11.9 1.5 1.6 1 0 0 1 1 1 0 Tctex-1 family Complex1_LYR PF05347.15 EGG20485.1 - 4.1e-12 46.0 0.2 4.1e-12 46.0 0.2 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGG20485.1 - 0.0014 19.3 0.8 0.0033 18.1 0.8 1.7 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EGG20485.1 - 0.0025 18.4 0.0 0.0037 17.8 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF1505 PF07403.11 EGG20487.1 - 0.0055 16.9 6.3 0.0055 16.9 6.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1505) TPPK_C PF12555.8 EGG20487.1 - 1.3 9.2 7.5 13 6.0 3.7 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Isochorismatase PF00857.20 EGG20488.1 - 8.1e-30 104.3 0.0 2.8e-29 102.5 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family Ninjurin PF04923.12 EGG20489.1 - 0.052 13.5 0.9 0.078 12.9 0.9 1.4 1 0 0 1 1 1 0 Ninjurin VanW PF04294.13 EGG20489.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 VanW like protein Tn7_Tnp_TnsA_C PF08721.11 EGG20489.1 - 0.18 12.5 1.5 0.2 12.3 0.1 1.8 2 0 0 2 2 2 0 TnsA endonuclease C terminal Ank_4 PF13637.6 EGG20490.1 - 1.1e-15 57.8 0.0 1.7e-10 41.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG20490.1 - 1.1e-11 45.1 0.0 4e-05 24.1 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG20490.1 - 1.9e-07 31.2 0.0 0.00074 19.8 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGG20490.1 - 2.1e-06 27.9 0.0 0.0089 16.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGG20490.1 - 1.5e-05 25.0 0.0 0.15 12.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Cpn60_TCP1 PF00118.24 EGG20491.1 - 9.7e-152 506.0 18.2 1.1e-151 505.8 18.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 EGG20492.1 - 3e-37 128.0 0.0 6.7e-37 126.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG20492.1 - 1.5e-09 37.5 0.0 3.7e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EGG20492.1 - 1.6e-06 28.0 0.0 1e-05 25.4 0.0 2.4 3 0 0 3 3 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EGG20492.1 - 4.3e-05 23.3 0.0 8.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain SR-25 PF10500.9 EGG20492.1 - 0.0011 18.6 22.8 0.0011 18.6 22.8 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein AAA_5 PF07728.14 EGG20492.1 - 0.0012 18.8 0.3 0.0072 16.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGG20492.1 - 0.004 17.4 0.4 0.093 13.0 0.4 2.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EGG20492.1 - 0.0045 16.2 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EGG20492.1 - 0.0096 16.1 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EGG20492.1 - 0.035 13.5 0.1 0.077 12.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGG20492.1 - 0.036 13.6 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 EGG20492.1 - 0.037 14.4 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG20492.1 - 0.047 14.1 1.1 0.34 11.3 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 EGG20492.1 - 0.099 12.4 0.1 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 EGG20492.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGG20492.1 - 0.23 12.0 3.5 0.48 11.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain Chorion_2 PF03964.15 EGG20492.1 - 0.96 10.3 13.1 0.29 12.0 9.6 2.0 2 0 0 2 2 1 0 Chorion family 2 BUD22 PF09073.10 EGG20492.1 - 5.8 6.1 22.7 0.074 12.4 14.7 1.8 2 0 0 2 2 2 0 BUD22 GATA PF00320.27 EGG20493.1 - 1.3e-14 53.5 4.0 1.3e-14 53.5 4.0 2.0 2 0 0 2 2 2 1 GATA zinc finger Presenilin PF01080.17 EGG20494.1 - 0.55 8.9 6.7 0.68 8.6 6.7 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 EGG20494.1 - 1.2 7.6 10.9 1.6 7.2 10.9 1.1 1 0 0 1 1 1 0 Macoilin family FAM76 PF16046.5 EGG20494.1 - 8.4 5.7 10.1 11 5.2 10.1 1.1 1 0 0 1 1 1 0 FAM76 protein UCH PF00443.29 EGG20495.1 - 3.9e-45 154.4 0.3 5.6e-45 153.8 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG20495.1 - 1e-19 71.3 0.1 1.4e-19 70.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGG20495.1 - 4.7e-12 45.5 0.0 1.3e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 EGG20495.1 - 0.00063 19.3 0.2 0.018 14.5 0.1 3.1 4 0 0 4 4 4 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Nmad4 PF18756.1 EGG20495.1 - 0.038 14.3 0.2 0.2 12.0 0.3 2.2 2 0 0 2 2 2 0 Nucleotide modification associated domain 4 Rad60-SLD PF11976.8 EGG20495.1 - 0.1 12.4 0.1 0.28 11.0 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Abhydrolase_2 PF02230.16 EGG20496.1 - 3.1e-38 131.8 0.1 3.6e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EGG20496.1 - 8.1e-05 22.0 0.4 0.76 9.0 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EGG20496.1 - 0.0011 18.7 0.0 0.0021 17.7 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EGG20496.1 - 0.0092 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.9 EGG20496.1 - 0.017 14.6 0.0 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 EGG20496.1 - 0.019 15.6 0.0 0.25 11.9 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGG20496.1 - 0.026 14.0 0.5 4.3 6.7 0.0 2.9 2 1 1 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGG20496.1 - 0.066 13.1 0.0 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Myosin_TH1 PF06017.13 EGG20497.1 - 3e-25 89.0 7.6 1.6e-23 83.4 4.9 2.5 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding DUF4506 PF14958.6 EGG20498.1 - 2.5e-08 33.6 0.1 2.5e-08 33.6 0.1 2.1 3 0 0 3 3 2 1 Domain of unknown function (DUF4506) SR-25 PF10500.9 EGG20498.1 - 1.9e-05 24.4 11.6 1.9e-05 24.4 11.6 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 EGG20498.1 - 0.0016 18.9 37.4 0.046 14.3 11.6 2.7 2 0 0 2 2 2 2 Secretin N-terminal domain Pex14_N PF04695.13 EGG20498.1 - 0.0039 17.8 15.1 0.35 11.5 12.1 2.3 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region SPX PF03105.19 EGG20498.1 - 0.033 14.1 17.4 0.087 12.7 17.5 1.8 1 1 0 1 1 1 0 SPX domain AF-4 PF05110.13 EGG20498.1 - 0.085 10.9 23.4 0.0035 15.5 16.4 1.8 2 0 0 2 2 2 0 AF-4 proto-oncoprotein TCP PF03634.13 EGG20498.1 - 0.78 10.3 16.9 1.8 9.1 7.2 2.5 2 0 0 2 2 2 0 TCP family transcription factor SMYLE_N PF18615.1 EGG20498.1 - 1 8.9 9.4 1.1 8.8 5.5 2.1 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Presenilin PF01080.17 EGG20498.1 - 2.4 6.8 10.6 7.2 5.3 0.2 2.2 2 0 0 2 2 2 0 Presenilin Striatin PF08232.12 EGG20498.1 - 2.6 8.6 13.0 8.8 6.9 0.1 2.8 3 0 0 3 3 3 0 Striatin family CCSAP PF15748.5 EGG20498.1 - 3.2 7.8 12.8 1.1 9.3 6.9 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated CSG2 PF16965.5 EGG20498.1 - 3.8 6.4 8.9 1.7 7.5 1.2 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator Chorion_2 PF03964.15 EGG20498.1 - 5.1 8.0 12.1 0.3 11.9 6.6 1.8 2 0 0 2 2 1 0 Chorion family 2 DUF4614 PF15391.6 EGG20498.1 - 6 6.8 21.3 1.4 8.8 14.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) POX PF07526.11 EGG20498.1 - 9.3 6.8 14.5 9.4 6.8 3.5 3.1 3 0 0 3 3 3 0 Associated with HOX CXCXC PF03128.14 EGG20500.1 - 1.2 9.8 13.5 0.051 14.0 3.1 4.0 3 0 0 3 3 3 0 CXCXC repeat AAA_2 PF07724.14 EGG20501.1 - 9.2e-06 25.9 1.5 1.3e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGG20501.1 - 0.0016 18.8 0.1 0.0073 16.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGG20501.1 - 0.003 17.6 0.0 0.013 15.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG20501.1 - 0.0052 17.2 0.3 0.48 10.8 0.3 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG20501.1 - 0.0082 16.4 3.6 0.053 13.8 0.2 3.3 2 1 0 2 2 2 1 AAA domain Torsin PF06309.11 EGG20501.1 - 0.016 15.3 0.1 0.096 12.8 0.1 2.4 2 1 0 2 2 2 0 Torsin AAA_18 PF13238.6 EGG20501.1 - 0.022 15.3 0.3 0.095 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGG20501.1 - 0.027 14.5 0.6 0.5 10.4 0.1 2.9 2 2 0 2 2 2 0 AAA domain (dynein-related subfamily) DBI_PRT PF02277.17 EGG20501.1 - 0.031 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase AAA_24 PF13479.6 EGG20501.1 - 0.11 12.2 0.0 0.11 12.2 0.0 2.8 4 0 0 4 4 4 0 AAA domain zf-TRAF_2 PF15965.5 EGG20501.1 - 0.13 12.8 0.5 0.64 10.5 0.3 2.0 2 0 0 2 2 2 0 TRAF-like zinc-finger Fungal_trans PF04082.18 EGG20502.1 - 0.15 11.1 8.5 0.22 10.5 0.2 3.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain HSP70 PF00012.20 EGG20505.1 - 6.6e-132 440.7 1.9 7.6e-132 440.5 0.2 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGG20505.1 - 3.9e-13 48.9 0.1 2.1e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein BLOC1S3 PF15753.5 EGG20505.1 - 2.1 8.4 7.4 2.5 8.2 3.9 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 LIM PF00412.22 EGG20506.1 - 1.2e-24 86.3 31.8 9.3e-09 35.4 5.2 3.4 3 0 0 3 3 3 3 LIM domain C1_1 PF00130.22 EGG20506.1 - 0.00011 22.0 22.9 0.31 11.0 2.2 3.5 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) CMV_US PF08001.11 EGG20506.1 - 0.051 12.9 2.7 0.052 12.8 0.1 2.2 3 0 0 3 3 3 0 CMV US PHF5 PF03660.14 EGG20506.1 - 0.1 12.8 19.3 2.8 8.2 1.7 3.4 3 0 0 3 3 3 0 PHF5-like protein DUF3716 PF12511.8 EGG20506.1 - 0.14 12.2 21.7 0.47 10.5 1.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3716) TNFR_c6 PF00020.18 EGG20506.1 - 0.31 11.5 24.3 5.5 7.5 0.7 6.2 6 0 0 6 6 6 0 TNFR/NGFR cysteine-rich region XAF1_C PF18608.1 EGG20506.1 - 0.4 10.3 7.4 5.2 6.7 0.9 3.6 3 0 0 3 3 3 0 XIAP-associated factor 1 C-terminal domain MTHFR_C PF12225.8 EGG20506.1 - 1.2 8.8 27.7 0.23 11.1 0.4 5.1 4 3 2 6 6 6 0 Methylene-tetrahydrofolate reductase C terminal SAND PF01342.21 EGG20506.1 - 4.8 7.0 10.6 8.8 6.1 0.3 3.6 3 0 0 3 3 3 0 SAND domain Sulfotransfer_1 PF00685.27 EGG20507.1 - 7.8e-20 71.5 1.1 6.9e-19 68.3 1.1 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGG20507.1 - 6.5e-19 69.2 0.3 1.1e-05 25.9 0.0 3.5 2 1 1 3 3 3 3 Sulfotransferase family Sulfotransfer_2 PF03567.14 EGG20507.1 - 0.026 14.4 0.1 0.069 13.0 0.1 1.9 2 0 0 2 2 2 0 Sulfotransferase family SlyX PF04102.12 EGG20507.1 - 0.13 12.8 0.4 0.3 11.7 0.4 1.6 1 0 0 1 1 1 0 SlyX Proteasome PF00227.26 EGG20508.1 - 1.9e-48 164.5 0.3 2.4e-48 164.2 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_S5 PF00333.20 EGG20509.1 - 7e-30 102.8 1.8 1.2e-29 102.1 1.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGG20509.1 - 8e-15 54.1 0.1 1.7e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FNIP PF05725.12 EGG20510.1 - 0.0037 17.4 10.8 0.015 15.4 2.9 9.7 7 2 2 10 10 10 2 FNIP Repeat LRR_5 PF13306.6 EGG20510.1 - 0.21 11.5 0.1 0.21 11.5 0.1 4.6 4 2 1 5 5 5 0 BspA type Leucine rich repeat region (6 copies) Androgen_recep PF02166.16 EGG20510.1 - 4.7 6.0 5.6 6.4 5.5 5.6 1.1 1 0 0 1 1 1 0 Androgen receptor SUIM_assoc PF16619.5 EGG20510.1 - 7.6 6.7 13.5 21 5.2 13.5 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RCC1 PF00415.18 EGG20512.1 - 8.3e-25 87.2 4.5 8.2e-09 36.0 0.0 7.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG20512.1 - 5.8e-22 76.9 12.6 7e-06 25.7 0.0 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EGG20512.1 - 2.7e-16 59.8 3.8 2.3e-09 37.5 0.1 4.1 3 0 0 3 3 3 3 BTB/POZ domain zf-C2H2_jaz PF12171.8 EGG20514.1 - 3.2e-05 24.1 3.6 3.2e-05 24.1 3.6 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG20514.1 - 0.00067 20.0 3.1 0.0016 18.7 3.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Ribosomal_60s PF00428.19 EGG20514.1 - 0.039 14.5 4.6 0.039 14.5 4.6 4.0 4 0 0 4 4 4 0 60s Acidic ribosomal protein RRM_1 PF00076.22 EGG20516.1 - 9e-17 60.7 1.8 2.7e-09 36.7 0.1 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG20516.1 - 0.23 11.5 0.8 5.7 7.0 0.1 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGG20516.1 - 0.41 10.7 4.7 1.7 8.7 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif Glyco_hydro_38N PF01074.22 EGG20517.1 - 5.7e-95 318.0 3.3 1.1e-94 317.1 3.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGG20517.1 - 2.7e-32 112.6 0.2 4.4e-32 111.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGG20517.1 - 3.5e-20 72.0 0.0 8.9e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EGG20517.1 - 0.00088 19.3 0.1 0.0033 17.5 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 EGG20517.1 - 0.0067 15.7 0.1 0.078 12.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 BRCT_2 PF16589.5 EGG20518.1 - 1.7e-09 37.9 1.2 9.2e-09 35.6 0.3 2.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG20518.1 - 7e-09 36.0 0.7 6.8e-08 32.8 0.2 2.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGG20518.1 - 0.0036 17.2 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain RRM_1 PF00076.22 EGG20518.1 - 0.022 14.6 0.0 0.077 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IES5 PF17335.2 EGG20520.1 - 0.055 13.7 0.2 0.12 12.7 0.1 1.6 2 0 0 2 2 2 0 Ino80 complex subunit 5 LIM PF00412.22 EGG20521.1 - 5.3e-59 196.3 51.7 5.4e-15 55.4 1.7 5.2 5 0 0 5 5 5 5 LIM domain RNA_pol_3_Rpc31 PF11705.8 EGG20521.1 - 0.54 10.5 8.6 0.87 9.8 8.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 zf-B_box PF00643.24 EGG20522.1 - 3.3e-08 33.5 7.8 7.6e-08 32.4 7.8 1.6 1 0 0 1 1 1 1 B-box zinc finger Kelch_6 PF13964.6 EGG20522.1 - 8e-05 22.8 0.5 0.0061 16.8 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 EGG20522.1 - 0.0029 17.2 1.2 0.028 14.0 0.1 3.0 4 0 0 4 4 4 1 Kelch motif RRM_1 PF00076.22 EGG20522.1 - 0.016 15.0 0.1 0.17 11.7 0.1 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5305 PF17231.2 EGG20523.1 - 0.0097 15.3 0.3 0.015 14.7 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Collectrin PF16959.5 EGG20523.1 - 0.066 13.0 0.3 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Renal amino acid transporter CrgA PF06781.12 EGG20523.1 - 0.069 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Cell division protein CrgA EGF_2 PF07974.13 EGG20524.1 - 3.1e-06 27.5 33.8 0.0017 18.7 15.4 2.6 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 EGG20524.1 - 7.7e-06 26.3 25.2 0.016 15.8 6.9 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF EGF PF00008.27 EGG20524.1 - 0.00015 22.0 31.5 0.0086 16.4 8.4 3.0 3 0 0 3 3 3 2 EGF-like domain Laminin_EGF PF00053.24 EGG20524.1 - 0.008 16.3 21.2 0.36 11.0 7.6 2.5 1 1 1 2 2 2 2 Laminin EGF domain cEGF PF12662.7 EGG20524.1 - 0.15 12.0 9.5 2.7 8.0 0.9 3.3 2 0 0 2 2 2 0 Complement Clr-like EGF-like Rhodanese PF00581.20 EGG20525.1 - 2.8e-12 47.1 0.0 4.3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Menin PF05053.13 EGG20525.1 - 0.04 12.3 1.9 0.04 12.3 1.9 1.1 1 0 0 1 1 1 0 Menin Peptidase_C12 PF01088.21 EGG20526.1 - 2.2e-71 239.9 0.0 3.8e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EGG20526.1 - 9.5e-18 63.8 3.4 9.5e-18 63.8 3.4 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases PilS PF08805.11 EGG20526.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 PilS N terminal VWA PF00092.28 EGG20527.1 - 7.7e-12 45.8 0.0 8.7e-11 42.4 0.0 3.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGG20527.1 - 2.4e-10 41.0 0.9 4.1e-09 37.0 0.1 3.6 3 0 0 3 3 3 1 von Willebrand factor type A domain Med25_VWA PF11265.8 EGG20527.1 - 0.042 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A F-box-like PF12937.7 EGG20527.1 - 0.081 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 F-box-like DUF4508 PF14969.6 EGG20527.1 - 0.15 12.4 10.0 8.3 6.7 0.2 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4508) DUF3439 PF11921.8 EGG20527.1 - 0.72 9.8 13.9 3.3 7.7 13.9 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.25 EGG20528.1 - 2e-71 240.5 0.0 2e-71 240.5 0.0 3.6 6 0 0 6 6 6 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20528.1 - 6.6e-49 166.5 0.0 4.1e-48 163.9 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Cullin_binding PF03556.15 EGG20529.1 - 1.7e-31 109.1 0.9 1.7e-31 109.1 0.9 2.8 2 1 1 3 3 3 1 Cullin binding UBA_4 PF14555.6 EGG20529.1 - 1.2e-11 44.2 0.0 2.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain S-methyl_trans PF02574.16 EGG20529.1 - 0.17 11.7 0.0 0.23 11.2 0.0 1.5 1 1 0 1 1 1 0 Homocysteine S-methyltransferase rve_2 PF13333.6 EGG20529.1 - 0.29 11.4 1.7 4.2 7.6 0.3 3.0 2 1 1 3 3 3 0 Integrase core domain EF-hand_6 PF13405.6 EGG20529.1 - 0.6 10.2 3.0 4.8 7.4 0.3 3.0 3 0 0 3 3 3 0 EF-hand domain HSP20 PF00011.21 EGG20530.1 - 3.8e-19 68.7 0.0 4.3e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG20530.1 - 1e-05 25.0 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Pkinase PF00069.25 EGG20531.1 - 3.1e-35 121.8 0.0 7.5e-34 117.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20531.1 - 4.1e-25 88.5 0.0 7e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGG20531.1 - 0.00035 20.0 0.0 0.051 12.9 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGG20531.1 - 0.0018 17.6 0.0 0.0076 15.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGG20531.1 - 0.003 16.4 1.2 0.0073 15.1 0.2 1.8 1 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGG20531.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3887 PF13026.6 EGG20531.1 - 0.15 12.9 0.1 0.28 12.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3887) SR-25 PF10500.9 EGG20531.1 - 2.8 7.5 6.0 5.5 6.5 6.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Patatin PF01734.22 EGG20532.1 - 4.4e-22 79.3 0.0 6.4e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase Reovirus_L2 PF06016.11 EGG20532.1 - 0.069 10.3 0.0 0.094 9.9 0.0 1.1 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) DUF3446 PF11928.8 EGG20533.1 - 6.8 7.1 26.7 0.23 11.8 6.8 3.7 4 0 0 4 4 4 0 Early growth response N-terminal domain CBF PF03914.17 EGG20534.1 - 1.1e-33 116.7 2.6 1.1e-33 116.7 2.6 3.9 4 2 0 4 4 4 1 CBF/Mak21 family LRR_8 PF13855.6 EGG20534.1 - 1.1e-08 34.7 10.8 0.00037 20.2 0.8 5.0 3 1 1 4 4 4 2 Leucine rich repeat F-box PF00646.33 EGG20534.1 - 0.03 14.2 0.7 0.27 11.2 0.1 2.9 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.7 EGG20534.1 - 0.11 13.0 22.3 0.15 12.5 0.9 7.2 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) Exo_endo_phos PF03372.23 EGG20535.1 - 0.00012 21.7 0.1 0.00034 20.2 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CAP_N PF01213.19 EGG20535.1 - 0.95 8.9 8.7 0.17 11.3 0.6 2.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal SUIM_assoc PF16619.5 EGG20535.1 - 9.1 6.4 16.0 0.2 11.7 0.2 3.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 STD1 PF17235.2 EGG20536.1 - 0.013 15.2 0.5 0.02 14.6 0.5 1.3 1 0 0 1 1 1 0 STD1/MTH1 Oxysterol_BP PF01237.18 EGG20537.1 - 6.3e-80 268.8 8.8 7.9e-78 261.9 8.8 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF4124 PF13511.6 EGG20537.1 - 6.8 7.1 7.0 16 5.9 7.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) ERCC4 PF02732.15 EGG20538.1 - 4.8e-17 62.6 5.9 1.3e-16 61.2 0.0 3.0 3 0 0 3 3 3 1 ERCC4 domain 5_3_exonuc PF01367.20 EGG20538.1 - 0.0028 18.2 0.4 1.1 9.9 0.0 3.0 2 0 0 2 2 2 2 5'-3' exonuclease, C-terminal SAM fold SWIM PF04434.17 EGG20538.1 - 0.0031 17.1 0.5 0.0064 16.1 0.5 1.4 1 0 0 1 1 1 1 SWIM zinc finger HHH PF00633.23 EGG20538.1 - 0.025 14.5 0.3 0.21 11.5 0.1 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Levi_coat PF01819.17 EGG20539.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Levivirus coat protein GATA PF00320.27 EGG20540.1 - 2.7e-06 26.9 6.3 2.7e-06 26.9 6.3 2.6 2 1 1 3 3 3 1 GATA zinc finger DZR PF12773.7 EGG20540.1 - 3.1 7.9 11.0 4.5e+02 1.0 10.5 3.0 1 1 0 1 1 1 0 Double zinc ribbon zf-HIT PF04438.16 EGG20540.1 - 4.6 7.2 7.5 3.2 7.7 0.7 2.8 2 0 0 2 2 2 0 HIT zinc finger PHD PF00628.29 EGG20540.1 - 6 6.8 14.7 0.13 12.2 5.5 2.6 1 1 0 2 2 2 0 PHD-finger PMSR PF01625.21 EGG20541.1 - 2.4e-60 203.1 2.7 4.4e-60 202.3 2.7 1.4 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Ras PF00071.22 EGG20541.1 - 2.1e-45 154.3 0.2 3.8e-45 153.4 0.2 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG20541.1 - 2.7e-15 56.6 0.0 6.6e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG20541.1 - 1.9e-06 27.4 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Fz PF01392.22 EGG20541.1 - 2.3e-06 28.2 2.7 5.7e-06 26.9 2.7 1.7 1 0 0 1 1 1 1 Fz domain MMR_HSR1 PF01926.23 EGG20541.1 - 0.00096 19.2 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG20541.1 - 0.011 15.2 0.1 0.023 14.2 0.1 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF1129 PF06570.11 EGG20541.1 - 0.08 12.4 0.3 0.2 11.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Methyltransf_11 PF08241.12 EGG20543.1 - 3e-17 63.1 0.0 1.6e-15 57.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG20543.1 - 1.8e-15 57.4 0.0 3.5e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EGG20543.1 - 6.3e-15 55.4 0.0 8.6e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG20543.1 - 2e-13 50.4 0.0 1.2e-06 28.4 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGG20543.1 - 5.1e-13 49.6 0.0 2.6e-12 47.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG20543.1 - 1.9e-07 30.7 0.0 8.2e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family MetW PF07021.12 EGG20543.1 - 0.0056 16.3 0.1 0.17 11.4 0.0 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW DUF3446 PF11928.8 EGG20543.1 - 0.01 16.1 9.4 0.019 15.3 9.4 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain CMAS PF02353.20 EGG20543.1 - 0.013 14.8 0.0 0.086 12.1 0.0 2.1 3 0 0 3 3 3 0 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 EGG20543.1 - 0.018 13.7 0.0 0.043 12.4 0.0 1.5 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PAP1 PF08601.10 EGG20543.1 - 0.032 14.0 1.6 0.042 13.6 1.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 SR-25 PF10500.9 EGG20543.1 - 0.15 11.6 8.2 0.22 11.1 8.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF5470 PF17564.2 EGG20543.1 - 0.17 12.1 3.9 0.38 11.0 3.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5470) TPMT PF05724.11 EGG20543.1 - 0.19 11.3 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Herpes_pp85 PF04637.12 EGG20543.1 - 5.3 5.3 6.6 7.6 4.8 6.6 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Erg28 PF03694.13 EGG20544.1 - 2.5e-30 105.1 5.5 2.9e-30 104.9 5.5 1.0 1 0 0 1 1 1 1 Erg28 like protein Polyketide_cyc PF03364.20 EGG20544.1 - 0.1 12.8 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport LSM PF01423.22 EGG20545.1 - 1.9e-06 27.5 5.6 3.5e-06 26.6 0.3 2.5 2 1 0 2 2 2 1 LSM domain SDA1 PF05285.12 EGG20545.1 - 2.3e-05 24.0 10.1 2.5e-05 23.9 10.1 1.3 1 0 0 1 1 1 1 SDA1 BSP_II PF05432.11 EGG20545.1 - 0.0039 16.9 16.6 0.0058 16.4 16.6 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 EGG20545.1 - 0.0084 14.5 7.0 0.0089 14.4 7.0 1.2 1 0 0 1 1 1 1 CDC45-like protein RNA_pol_Rpc4 PF05132.14 EGG20545.1 - 0.019 15.4 2.1 0.033 14.6 2.1 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 EGG20545.1 - 0.035 14.3 5.6 0.059 13.6 5.6 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ICA69 PF04629.14 EGG20545.1 - 0.052 13.9 10.0 0.068 13.5 10.0 1.3 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain PI3K_1B_p101 PF10486.9 EGG20545.1 - 0.052 11.3 8.1 0.07 10.9 8.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DDHD PF02862.17 EGG20545.1 - 0.098 12.8 1.6 0.11 12.7 1.6 1.3 1 0 0 1 1 1 0 DDHD domain NOA36 PF06524.12 EGG20545.1 - 0.16 11.2 11.1 0.26 10.6 11.1 1.4 1 0 0 1 1 1 0 NOA36 protein DUF740 PF05340.12 EGG20545.1 - 0.21 10.3 7.2 0.23 10.1 6.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF740) DUF913 PF06025.12 EGG20545.1 - 0.28 10.1 5.8 0.39 9.6 5.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 EGG20545.1 - 0.3 10.8 6.4 0.54 10.0 6.4 1.3 1 0 0 1 1 1 0 Connexin DUF4484 PF14831.6 EGG20545.1 - 0.37 10.8 9.7 0.6 10.1 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) PIEZO PF15917.5 EGG20545.1 - 0.45 9.9 8.0 0.94 8.9 8.0 1.5 1 0 0 1 1 1 0 Piezo ALMT PF11744.8 EGG20545.1 - 0.7 8.7 6.6 1 8.1 6.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Roughex PF06020.11 EGG20545.1 - 0.75 8.8 10.7 1 8.4 10.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Nucleoside_tran PF01733.18 EGG20545.1 - 1.1 8.6 4.4 1.7 8.0 4.4 1.3 1 0 0 1 1 1 0 Nucleoside transporter Presenilin PF01080.17 EGG20545.1 - 1.2 7.9 9.2 1.8 7.3 9.2 1.2 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 EGG20545.1 - 1.3 7.4 3.6 1.3 7.3 3.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TRAP_alpha PF03896.16 EGG20545.1 - 1.4 8.1 13.0 2 7.5 13.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Otopetrin PF03189.13 EGG20545.1 - 1.6 7.5 3.3 1.8 7.3 3.3 1.1 1 0 0 1 1 1 0 Otopetrin Cellulose_synt PF03552.14 EGG20545.1 - 1.7 7.1 4.5 3.4 6.0 4.5 1.5 2 0 0 2 2 2 0 Cellulose synthase DNA_pol_phi PF04931.13 EGG20545.1 - 1.8 6.6 21.6 2.2 6.3 21.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_U57 PF05582.12 EGG20545.1 - 1.9 7.7 9.9 1.5 8.0 8.4 1.5 1 1 0 2 2 2 0 YabG peptidase U57 DUF4820 PF16091.5 EGG20545.1 - 2.1 7.7 9.2 3.5 6.9 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CAC1F_C PF16885.5 EGG20545.1 - 3 7.4 11.4 1 9.0 7.1 1.8 1 1 1 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term CobT PF06213.12 EGG20545.1 - 5.1 6.4 22.5 7.3 5.9 21.7 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT CLN3 PF02487.17 EGG20545.1 - 6.5 5.7 7.4 9.3 5.2 7.4 1.2 1 0 0 1 1 1 0 CLN3 protein Ureide_permease PF07168.11 EGG20545.1 - 8.1 5.1 8.1 12 4.5 8.1 1.2 1 0 0 1 1 1 0 Ureide permease FAM60A PF15396.6 EGG20545.1 - 8.9 6.2 8.2 1.6 8.7 4.9 1.4 2 0 0 2 2 1 0 Protein Family FAM60A RhoGEF PF00621.20 EGG20546.1 - 3.9e-37 128.3 9.7 3.9e-37 128.3 9.7 3.5 2 1 1 3 3 3 1 RhoGEF domain PH PF00169.29 EGG20546.1 - 5.3e-05 23.7 0.7 0.00022 21.7 0.1 2.4 2 0 0 2 2 2 1 PH domain DNA_pol_E_B PF04042.16 EGG20547.1 - 2.2e-34 118.7 0.3 3.7e-34 117.9 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EGG20547.1 - 4.3e-31 107.7 0.0 7.8e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DUF3144 PF11342.8 EGG20547.1 - 0.12 12.7 0.9 0.2 12.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) BB_PF PF18063.1 EGG20550.1 - 6.3e-56 189.2 7.5 7.2e-56 189.0 7.5 1.0 1 0 0 1 1 1 1 Beta barrel Pore-forming domain BB_PF PF18063.1 EGG20551.1 - 0.00019 21.1 0.0 0.00022 20.9 0.0 1.1 1 0 0 1 1 1 1 Beta barrel Pore-forming domain Pilin PF00114.19 EGG20552.1 - 0.071 14.0 0.4 0.18 12.8 0.2 1.9 1 1 0 2 2 2 0 Pilin (bacterial filament) Patatin PF01734.22 EGG20553.1 - 8.1e-15 55.5 0.0 1.4e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Rhodanese PF00581.20 EGG20553.1 - 0.0018 18.8 0.2 0.055 14.0 0.2 2.8 1 1 0 1 1 1 1 Rhodanese-like domain FNIP PF05725.12 EGG20554.1 - 2.2e-05 24.5 18.6 3 8.1 0.0 7.8 7 2 0 7 7 7 5 FNIP Repeat TPT PF03151.16 EGG20555.1 - 1.1e-22 80.8 18.3 1.3e-22 80.5 18.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGG20555.1 - 1.4e-06 28.5 16.8 1.4e-06 28.5 16.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGG20555.1 - 2.5e-05 23.6 21.6 0.00019 20.8 21.5 2.0 1 1 0 1 1 1 1 UAA transporter family EVI2A PF05399.11 EGG20555.1 - 0.043 13.4 0.7 0.078 12.6 0.7 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Adeno_E1B_55K_N PF04623.12 EGG20555.1 - 0.94 10.2 5.2 1.8 9.3 5.2 1.4 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus ESSS PF10183.9 EGG20555.1 - 1.2 9.3 7.7 8.1 6.7 0.6 3.1 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ubiquitin PF00240.23 EGG20556.1 - 4.3e-34 116.1 0.4 7.1e-34 115.4 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EGG20556.1 - 2.1e-22 79.0 3.1 4.8e-22 77.8 3.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EGG20556.1 - 9.5e-16 57.4 0.4 1.6e-15 56.7 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGG20556.1 - 4.6e-05 23.8 0.1 0.00019 21.8 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGG20556.1 - 0.0031 17.6 0.2 0.0077 16.3 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGG20556.1 - 0.004 17.5 1.0 0.012 16.0 0.0 1.9 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGG20556.1 - 0.01 15.7 0.1 0.022 14.7 0.1 1.6 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EGG20556.1 - 0.025 15.1 0.2 0.032 14.8 0.2 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGG20556.1 - 0.04 14.0 0.7 9.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Zn-ribbon_8 PF09723.10 EGG20556.1 - 0.097 12.8 0.6 0.18 11.9 0.6 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 EGG20556.1 - 0.17 12.0 2.4 1.2 9.3 2.8 1.9 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 EGG20556.1 - 0.36 10.6 4.5 8.5 6.2 0.5 3.0 3 0 0 3 3 3 0 zinc-ribbon domain TPD PF14811.6 EGG20558.1 - 2.7e-46 156.8 0.4 5e-46 155.9 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif Zip PF02535.22 EGG20558.1 - 0.023 13.9 1.9 0.028 13.6 1.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter AAR2 PF05282.11 EGG20558.1 - 0.034 13.6 2.9 0.051 13.0 2.9 1.4 1 0 0 1 1 1 0 AAR2 protein Macoilin PF09726.9 EGG20558.1 - 0.17 10.4 8.9 0.18 10.3 8.9 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 EGG20558.1 - 0.22 10.3 8.6 0.28 9.9 8.6 1.1 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 EGG20558.1 - 0.31 10.8 7.7 0.62 9.8 7.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Gti1_Pac2 PF09729.9 EGG20558.1 - 0.33 11.0 9.2 0.55 10.3 9.2 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family NPR3 PF03666.13 EGG20558.1 - 1.7 7.4 14.1 3.5 6.3 14.1 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4820 PF16091.5 EGG20558.1 - 1.9 7.8 3.9 2.5 7.4 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) ALMT PF11744.8 EGG20558.1 - 2.1 7.1 6.6 3 6.6 6.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CSG2 PF16965.5 EGG20558.1 - 2.4 7.0 4.8 3.7 6.4 4.8 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Tim54 PF11711.8 EGG20558.1 - 5.6 5.6 7.6 7.8 5.2 7.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SF3b10 PF07189.11 EGG20559.1 - 2.6e-35 120.4 0.0 3e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) BTB_2 PF02214.22 EGG20560.1 - 2.5e-23 82.2 0.0 5.3e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 EGG20560.1 - 2e-12 47.1 0.0 4.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Fis1_TPR_C PF14853.6 EGG20560.1 - 3.2e-07 30.3 0.2 6.2e-07 29.4 0.2 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 EGG20560.1 - 0.0041 17.8 0.5 0.014 16.1 0.0 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG20560.1 - 0.015 15.8 0.1 0.035 14.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ERCC4 PF02732.15 EGG20561.1 - 3.8e-17 62.9 0.0 3.8e-17 62.9 0.0 3.6 5 0 0 5 5 5 1 ERCC4 domain HHH_8 PF14716.6 EGG20561.1 - 7.6e-09 35.8 0.0 1.5e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain zf-RING_2 PF13639.6 EGG20562.1 - 1.5e-10 41.2 10.3 2.6e-10 40.5 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGG20562.1 - 4.7e-08 32.6 10.8 8.4e-08 31.8 10.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EGG20562.1 - 3.8e-07 30.3 6.9 1.6e-06 28.3 6.9 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGG20562.1 - 4.7e-05 23.1 10.2 8.8e-05 22.3 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG20562.1 - 0.00037 20.3 12.1 0.00083 19.2 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGG20562.1 - 0.015 15.3 2.9 0.015 15.3 2.9 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ribosomal_60s PF00428.19 EGG20562.1 - 0.015 15.8 0.1 0.015 15.8 0.1 1.8 2 0 0 2 2 1 0 60s Acidic ribosomal protein zf-RING_UBOX PF13445.6 EGG20562.1 - 0.026 14.5 10.0 0.061 13.4 10.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGG20562.1 - 0.074 12.9 8.6 0.12 12.2 8.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG20562.1 - 0.11 12.5 9.3 0.21 11.5 9.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EGG20562.1 - 0.15 11.7 7.5 0.28 10.9 7.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EGG20562.1 - 6.2 7.0 9.8 16 5.7 9.8 1.7 1 0 0 1 1 1 0 RING-variant domain Stealth_CR4 PF17103.5 EGG20563.1 - 0.12 12.3 0.2 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 Papilloma_E5A PF05776.12 EGG20564.1 - 1.3 9.4 5.0 0.6 10.5 1.7 2.1 2 0 0 2 2 2 0 Papillomavirus E5A protein SKG6 PF08693.10 EGG20565.1 - 0.046 13.1 1.4 0.1 12.0 1.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EGF_2 PF07974.13 EGG20565.1 - 0.056 13.8 10.2 0.13 12.6 10.2 1.6 1 0 0 1 1 1 0 EGF-like domain Trp_oprn_chp PF09534.10 EGG20565.1 - 0.27 11.0 0.1 0.45 10.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pept_tRNA_hydro PF01195.19 EGG20567.1 - 1.1e-40 139.4 0.3 5.8e-40 137.0 0.3 2.1 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF5523 PF17661.1 EGG20567.1 - 0.0012 18.6 7.3 0.0012 18.6 7.3 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5523) Connexin PF00029.19 EGG20567.1 - 0.0049 16.7 5.1 0.0049 16.7 5.1 1.9 2 0 0 2 2 2 1 Connexin CobT PF06213.12 EGG20567.1 - 0.031 13.7 8.3 0.062 12.7 8.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NST1 PF13945.6 EGG20567.1 - 0.036 14.2 27.6 0.04 14.0 10.2 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator U79_P34 PF03064.16 EGG20567.1 - 0.042 13.2 12.1 0.078 12.3 12.1 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Presenilin PF01080.17 EGG20567.1 - 0.22 10.2 13.1 0.25 10.1 2.6 2.1 2 0 0 2 2 2 0 Presenilin TAF4 PF05236.14 EGG20567.1 - 0.55 9.9 15.1 0.19 11.4 7.3 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family FAM76 PF16046.5 EGG20567.1 - 0.59 9.4 16.7 0.23 10.8 3.8 2.1 2 0 0 2 2 2 0 FAM76 protein Macoilin PF09726.9 EGG20567.1 - 0.94 8.0 20.2 1.3 7.5 20.2 1.1 1 0 0 1 1 1 0 Macoilin family Mucin PF01456.17 EGG20567.1 - 1.3 9.0 18.9 2.7 8.0 18.9 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein CPSF100_C PF13299.6 EGG20567.1 - 9.2 6.4 17.7 1.2 9.3 6.9 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF383 PF04063.14 EGG20568.1 - 6.6e-37 127.0 1.7 3.6e-36 124.6 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EGG20568.1 - 2.8e-18 65.5 0.6 9.2e-18 63.8 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF384) RasGEF_N_2 PF14663.6 EGG20568.1 - 0.00013 22.4 2.0 0.00066 20.1 0.4 2.8 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_2 PF13646.6 EGG20568.1 - 0.0032 17.8 0.2 3.2 8.2 0.1 3.2 2 1 0 2 2 2 2 HEAT repeats Cnd1 PF12717.7 EGG20568.1 - 0.016 15.2 1.8 0.025 14.6 0.5 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EGG20568.1 - 0.12 12.6 1.9 0.17 12.1 0.3 2.1 2 2 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 AAR2 PF05282.11 EGG20569.1 - 2e-82 277.4 18.7 4.1e-82 276.4 7.0 2.5 1 1 2 3 3 3 2 AAR2 protein DUF4770 PF15994.5 EGG20569.1 - 0.52 10.5 13.7 0.95 9.7 2.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4770) DUF3439 PF11921.8 EGG20569.1 - 0.71 9.9 3.5 1.4 8.9 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.11 EGG20569.1 - 1.2 9.1 7.8 2.6 7.9 7.8 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus UPF0767 PF15990.5 EGG20569.1 - 2 8.6 7.8 0.74 10.0 0.2 3.3 3 0 0 3 3 3 0 UPF0767 family FAD_oxidored PF12831.7 EGG20569.1 - 2.6 7.3 5.7 2.8 7.2 1.0 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase PH PF00169.29 EGG20570.1 - 6.1e-12 46.0 2.3 7.1e-12 45.8 0.3 2.2 3 0 0 3 3 3 1 PH domain PH_8 PF15409.6 EGG20570.1 - 0.0009 19.5 2.1 0.0037 17.5 2.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain SUIM_assoc PF16619.5 EGG20570.1 - 0.61 10.2 11.5 1.8 8.7 11.5 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PH_13 PF16652.5 EGG20570.1 - 0.66 9.8 5.9 0.16 11.8 2.1 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 EGG20570.1 - 2 8.9 11.0 3.2 8.2 6.4 3.4 2 2 0 2 2 2 0 Pleckstrin homology domain DUF2206 PF09971.9 EGG20571.1 - 0.0054 15.5 0.1 0.006 15.4 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2206) ENOD93 PF03386.14 EGG20571.1 - 0.044 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein DUF846 PF05832.12 EGG20572.1 - 1.6e-47 161.1 12.5 2.2e-47 160.6 12.5 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) COX14 PF14880.6 EGG20572.1 - 0.49 10.3 4.9 0.77 9.6 0.1 2.9 3 1 1 4 4 4 0 Cytochrome oxidase c assembly DSPc PF00782.20 EGG20573.1 - 2.5e-08 33.8 0.0 4.4e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG20573.1 - 2e-06 27.6 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EGG20573.1 - 0.00011 22.0 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 EGG20573.1 - 0.00059 20.0 0.0 0.00095 19.3 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate DHHC PF01529.20 EGG20574.1 - 5.1e-05 23.4 27.5 0.0016 18.5 7.0 3.4 2 1 1 3 3 3 2 DHHC palmitoyltransferase EMC3_TMCO1 PF01956.16 EGG20574.1 - 0.005 16.6 0.6 0.012 15.3 0.1 1.8 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like UPF0515 PF15135.6 EGG20574.1 - 0.024 14.0 1.4 0.043 13.2 1.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Tmemb_55A PF09788.9 EGG20574.1 - 0.034 13.2 0.5 0.034 13.2 0.5 2.3 3 0 0 3 3 3 0 Transmembrane protein 55A Oleosin PF01277.17 EGG20574.1 - 0.084 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Oleosin Menin PF05053.13 EGG20574.1 - 2.4 6.4 8.8 0.3 9.4 1.9 2.0 2 0 0 2 2 2 0 Menin DrsE_2 PF13686.6 EGG20575.1 - 0.098 12.5 4.3 0.13 12.2 3.5 1.7 1 1 1 2 2 2 0 DsrE/DsrF/DrsH-like family CDC45 PF02724.14 EGG20576.1 - 0.00081 17.8 8.5 0.00081 17.8 8.5 2.0 2 0 0 2 2 2 1 CDC45-like protein YL1 PF05764.13 EGG20576.1 - 0.0077 16.4 13.2 0.0077 16.4 13.2 1.7 2 0 0 2 2 2 1 YL1 nuclear protein FAM176 PF14851.6 EGG20576.1 - 0.014 15.1 1.2 0.014 15.1 1.2 2.4 2 0 0 2 2 2 0 FAM176 family SopA PF13981.6 EGG20576.1 - 0.02 15.3 0.8 0.047 14.1 0.1 2.0 2 0 0 2 2 2 0 SopA-like central domain DUF3784 PF12650.7 EGG20576.1 - 0.066 13.4 0.5 0.066 13.4 0.5 4.8 3 1 3 6 6 6 0 Domain of unknown function (DUF3784) Tmemb_185A PF10269.9 EGG20576.1 - 0.38 10.4 33.0 0.059 13.1 11.9 3.2 2 1 1 3 3 3 0 Transmembrane Fragile-X-F protein TRAP_alpha PF03896.16 EGG20576.1 - 0.54 9.4 4.4 1.4 8.0 4.4 1.7 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PI3K_1B_p101 PF10486.9 EGG20576.1 - 0.61 7.8 4.6 1 7.0 4.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pex14_N PF04695.13 EGG20576.1 - 1 10.0 4.4 15 6.2 1.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.11 EGG20576.1 - 1.5 6.8 12.6 2.6 6.0 12.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4611 PF15387.6 EGG20576.1 - 1.7 8.9 18.7 6.6 7.0 18.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 EGG20576.1 - 1.9 8.1 26.6 0.17 11.6 19.3 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EGG20576.1 - 2.4 6.1 28.6 0.039 12.1 17.1 2.2 2 0 0 2 2 2 0 DNA polymerase phi Pox_RNA_Pol_19 PF05320.12 EGG20576.1 - 10 6.1 21.1 1.7 8.6 0.3 2.5 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit TIG PF01833.24 EGG20579.1 - 3.9e-09 36.5 4.8 0.0006 19.8 0.4 2.4 2 0 0 2 2 2 2 IPT/TIG domain Inhibitor_I29 PF08246.12 EGG20581.1 - 2.8e-13 50.1 0.1 2.8e-13 50.1 0.1 2.3 2 1 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) TraT PF05818.12 EGG20581.1 - 0.086 12.5 1.0 0.12 12.0 1.0 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein BTRD1 PF17660.1 EGG20581.1 - 0.38 10.6 1.5 0.48 10.3 0.3 1.8 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 Peptidase_C1 PF00112.23 EGG20582.1 - 1.5e-49 169.1 0.2 2.2e-49 168.5 0.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.26 EGG20582.1 - 1.8e-08 35.2 2.8 3.7e-08 34.3 2.8 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Na_trans_assoc PF06512.13 EGG20583.1 - 0.0087 16.4 10.3 0.012 15.9 10.3 1.3 1 0 0 1 1 1 1 Sodium ion transport-associated SDA1 PF05285.12 EGG20583.1 - 0.51 9.7 25.8 0.77 9.1 25.8 1.3 1 0 0 1 1 1 0 SDA1 NPR3 PF03666.13 EGG20583.1 - 7.2 5.3 8.9 9.7 4.9 8.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 EGG20583.1 - 9.1 4.9 7.9 14 4.3 7.9 1.3 1 0 0 1 1 1 0 Presenilin ELO PF01151.18 EGG20584.1 - 1.6e-65 221.1 23.7 1.9e-65 220.9 23.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Malectin PF11721.8 EGG20585.1 - 0.032 14.3 0.0 0.12 12.4 0.0 2.0 1 0 0 1 1 1 0 Malectin domain FLgD_tudor PF13861.6 EGG20585.1 - 0.049 13.9 0.0 18 5.6 0.0 3.6 2 1 0 2 2 2 0 FlgD Tudor-like domain Bactofilin PF04519.13 EGG20585.1 - 2.5 8.4 5.9 11 6.4 0.1 4.2 3 1 1 4 4 4 0 Polymer-forming cytoskeletal Pentapeptide PF00805.22 EGG20586.1 - 1.1e-41 140.0 31.5 1.6e-14 53.2 5.0 4.1 2 2 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EGG20586.1 - 3e-24 85.0 1.4 1e-13 51.2 0.5 2.4 2 1 0 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EGG20586.1 - 3.7e-23 81.4 1.3 2e-09 37.5 2.0 4.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) DNA_ligase_OB PF03120.16 EGG20586.1 - 0.17 11.8 0.1 26 4.8 0.0 3.3 1 1 0 2 2 2 0 NAD-dependent DNA ligase OB-fold domain Aurora-A_bind PF09041.10 EGG20586.1 - 0.31 11.1 3.5 5.7 7.1 0.1 3.1 2 1 1 3 3 3 0 Aurora-A binding Acyltransferase PF01553.21 EGG20588.1 - 4e-17 62.1 0.2 1.6e-16 60.2 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase SRP40_C PF05022.12 EGG20589.1 - 5.7e-10 39.9 0.2 5.7e-10 39.9 0.2 3.7 3 2 0 3 3 3 1 SRP40, C-terminal domain Complex1_LYR PF05347.15 EGG20590.1 - 0.0012 18.8 0.1 0.0019 18.2 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Zn_clus PF00172.18 EGG20591.1 - 0.00017 21.6 10.9 0.00042 20.4 10.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EGG20592.1 - 9.8e-45 153.0 0.0 1.2e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20592.1 - 1.2e-22 80.5 0.0 1.4e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG20592.1 - 1e-06 28.9 0.0 0.0014 18.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG20592.1 - 5.9e-06 25.8 0.0 0.00016 21.1 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 EGG20592.1 - 0.0087 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Presenilin PF01080.17 EGG20593.1 - 1.9e-107 359.5 20.6 1.9e-107 359.5 20.6 2.7 2 1 0 2 2 2 1 Presenilin Pex14_N PF04695.13 EGG20593.1 - 1.2 9.7 0.0 1.2 9.7 0.0 3.7 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mur_ligase_M PF08245.12 EGG20594.1 - 6.7e-06 26.2 0.1 6.7e-06 26.2 0.1 3.9 2 2 2 4 4 4 1 Mur ligase middle domain DUF521 PF04412.13 EGG20594.1 - 0.051 12.3 0.0 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF521) DUF1029 PF06269.12 EGG20594.1 - 0.064 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1029) Tox-ODYAM1 PF15642.6 EGG20594.1 - 3.4 6.6 10.4 5.8 5.8 10.4 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF805 PF05656.14 EGG20596.1 - 0.72 10.3 4.8 4.3 7.8 4.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF1189 PF06691.11 EGG20596.1 - 1.6 8.2 6.7 4.2 6.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) Ribosomal_L35Ae PF01247.18 EGG20597.1 - 3.5e-37 126.4 1.4 5e-37 126.0 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae DUF2080 PF09853.9 EGG20597.1 - 0.0025 17.5 3.5 0.0063 16.2 0.1 2.8 3 0 0 3 3 3 1 Putative transposon-encoded protein (DUF2080) RimM PF01782.18 EGG20597.1 - 0.0077 16.4 0.0 3.3 8.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain TTRAP PF14203.6 EGG20597.1 - 0.13 12.3 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein Pkinase PF00069.25 EGG20598.1 - 1.1e-67 228.2 0.2 1.1e-67 228.2 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20598.1 - 1.7e-42 145.5 0.0 3.4e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG20598.1 - 1.2e-05 24.8 0.0 1.2e-05 24.8 0.0 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EGG20598.1 - 0.0029 17.6 0.2 0.0029 17.6 0.2 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGG20598.1 - 0.0057 15.8 0.1 0.029 13.4 0.0 2.1 2 0 0 2 2 2 1 Seadornavirus VP7 DUF4667 PF15700.5 EGG20598.1 - 0.05 13.7 7.2 0.082 13.0 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) DUF3552 PF12072.8 EGG20598.1 - 1.8 7.9 23.7 0.1 12.0 18.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) GPHR_N PF12537.8 EGG20598.1 - 2.8 8.1 5.4 13 5.9 0.1 3.2 2 1 1 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal FAM76 PF16046.5 EGG20598.1 - 3.3 7.0 10.2 0.5 9.7 5.4 2.0 2 0 0 2 2 2 0 FAM76 protein Exonuc_VII_L PF02601.15 EGG20598.1 - 3.7 7.0 11.7 6 6.3 11.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Histone PF00125.24 EGG20599.1 - 7.4e-47 159.0 3.9 8.3e-47 158.8 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGG20599.1 - 8.5e-06 25.8 0.2 1.6e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGG20599.1 - 0.00012 22.4 0.1 0.00018 21.8 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EGG20599.1 - 0.00029 21.4 0.7 0.00034 21.2 0.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain HisKA PF00512.25 EGG20599.1 - 0.01 15.8 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain TFIID-31kDa PF02291.15 EGG20599.1 - 0.016 15.2 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF1664 PF07889.12 EGG20600.1 - 0.057 13.5 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2076 PF09849.9 EGG20600.1 - 0.095 12.7 0.4 0.29 11.1 0.4 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FlaC_arch PF05377.11 EGG20600.1 - 0.1 13.0 3.6 0.49 10.8 0.8 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) SIKE PF05769.11 EGG20600.1 - 0.13 12.2 9.5 0.14 12.0 0.2 2.7 2 1 1 3 3 3 0 SIKE family TSC22 PF01166.18 EGG20600.1 - 0.51 10.7 7.9 0.064 13.6 3.3 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family SKA1 PF07160.12 EGG20600.1 - 1.4 8.7 8.3 4.9 6.9 8.3 2.0 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 RsgA_GTPase PF03193.16 EGG20601.1 - 0.00099 19.1 0.0 0.39 10.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase TMF_TATA_bd PF12325.8 EGG20602.1 - 0.019 15.2 4.4 0.042 14.1 3.6 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding VASP_tetra PF08776.11 EGG20602.1 - 0.24 11.0 10.0 0.49 10.0 1.9 2.6 2 0 0 2 2 2 0 VASP tetramerisation domain NEMO PF11577.8 EGG20602.1 - 0.84 9.7 7.8 0.18 11.8 3.4 2.1 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Qua1 PF16274.5 EGG20602.1 - 0.93 9.4 7.7 0.25 11.2 2.0 2.5 2 1 0 2 2 2 0 Qua1 domain DUF2205 PF10224.9 EGG20602.1 - 2.9 7.9 9.7 0.38 10.8 5.2 1.8 2 1 0 2 2 2 0 Short coiled-coil protein DUF349 PF03993.12 EGG20602.1 - 4.7 7.6 7.0 1.6 9.1 4.3 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) CorA PF01544.18 EGG20602.1 - 5.7 6.2 6.5 1.8 7.8 2.0 2.1 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Septin PF00735.18 EGG20603.1 - 0.0039 16.5 0.5 0.0076 15.6 0.5 1.4 1 0 0 1 1 1 1 Septin NB-ARC PF00931.22 EGG20603.1 - 0.0064 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RsgA_GTPase PF03193.16 EGG20603.1 - 0.0079 16.1 0.9 1.9 8.4 0.0 3.2 4 0 0 4 4 4 1 RsgA GTPase Sigma54_activat PF00158.26 EGG20603.1 - 0.0094 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 EGG20603.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGG20603.1 - 0.018 15.0 0.0 0.075 12.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 EGG20603.1 - 0.026 14.4 0.3 0.095 12.6 0.1 2.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 EGG20603.1 - 0.029 14.1 0.1 0.078 12.7 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EGG20603.1 - 0.037 13.8 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGG20603.1 - 0.12 12.9 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EGG20603.1 - 0.13 12.6 0.0 0.42 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGG20603.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EGG20603.1 - 0.21 12.0 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain EGF_2 PF07974.13 EGG20605.1 - 0.0062 16.9 12.8 0.0062 16.9 12.8 1.9 2 0 0 2 2 2 1 EGF-like domain EutH PF04346.12 EGG20605.1 - 0.019 14.2 0.1 0.031 13.4 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH HEAT PF02985.22 EGG20606.1 - 3.9e-06 26.7 0.1 0.016 15.4 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 EGG20606.1 - 0.0001 22.4 5.6 0.011 15.7 0.1 4.0 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGG20606.1 - 0.00044 20.8 3.3 0.0019 18.8 0.1 3.5 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGG20606.1 - 0.023 15.2 0.0 0.81 10.3 0.0 3.4 5 0 0 5 5 5 0 HEAT-like repeat EGF_2 PF07974.13 EGG20607.1 - 0.00051 20.4 16.0 0.0018 18.6 16.0 2.0 1 0 0 1 1 1 1 EGF-like domain AcetylCoA_hyd_C PF13336.6 EGG20607.1 - 0.035 14.0 0.4 0.09 12.7 0.4 1.6 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain fn3 PF00041.21 EGG20607.1 - 0.035 14.4 0.4 0.035 14.4 0.4 6.7 8 0 0 8 8 8 0 Fibronectin type III domain FIN1 PF17300.2 EGG20607.1 - 0.18 11.3 1.3 0.3 10.6 1.3 1.3 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 EGF PF00008.27 EGG20607.1 - 0.32 11.3 15.4 0.087 13.1 11.1 2.5 2 0 0 2 2 2 0 EGF-like domain Vac14_Fab1_bd PF12755.7 EGG20608.1 - 1e-08 35.7 7.8 6.8e-08 33.0 0.4 5.3 4 1 1 5 5 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGG20608.1 - 1.4e-06 28.0 1.6 0.069 13.4 0.1 5.9 6 0 0 6 6 5 1 HEAT repeat HEAT_2 PF13646.6 EGG20608.1 - 0.00018 21.8 0.0 1.2 9.5 0.0 4.7 3 0 0 3 3 3 1 HEAT repeats TIP120 PF08623.10 EGG20608.1 - 0.00027 20.7 1.4 0.0025 17.6 0.6 3.2 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) DUF4303 PF14136.6 EGG20608.1 - 0.005 16.6 0.3 0.075 12.8 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4303) Cnd1 PF12717.7 EGG20608.1 - 0.012 15.7 7.3 0.014 15.4 0.9 4.7 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 UCH PF00443.29 EGG20608.1 - 0.015 14.8 2.7 5.5 6.4 0.9 3.7 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF3452 PF11934.8 EGG20608.1 - 0.025 14.2 7.6 1.7 8.2 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) HEAT_EZ PF13513.6 EGG20608.1 - 0.17 12.4 0.1 12 6.6 0.0 3.8 3 0 0 3 3 2 0 HEAT-like repeat DUF996 PF06195.13 EGG20608.1 - 0.6 10.4 7.3 2.5 8.4 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF996) CLASP_N PF12348.8 EGG20608.1 - 2.1 7.9 9.4 0.23 11.0 0.7 3.7 4 1 1 5 5 5 0 CLASP N terminal PRC2_HTH_1 PF18118.1 EGG20608.1 - 3.6 8.5 6.3 4.6 8.1 1.0 2.9 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Antiterm PF03589.13 EGG20608.1 - 4.8 7.6 8.5 5.4 7.4 0.7 4.6 4 0 0 4 4 3 0 Antitermination protein 14-3-3 PF00244.20 EGG20608.1 - 6.8 6.1 14.6 0.07 12.6 0.2 3.7 4 0 0 4 4 4 0 14-3-3 protein HEAT PF02985.22 EGG20610.1 - 0.00035 20.6 0.1 0.016 15.5 0.2 3.2 3 0 0 3 3 3 1 HEAT repeat NDC10_II PF16787.5 EGG20610.1 - 0.0013 17.8 0.0 0.0026 16.9 0.0 1.5 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Importin_rep_4 PF18808.1 EGG20610.1 - 0.025 14.8 0.1 0.025 14.8 0.1 3.0 4 0 0 4 4 4 0 Importin repeat Tti2 PF10521.9 EGG20610.1 - 0.04 13.5 2.4 6.1 6.3 0.2 2.8 3 0 0 3 3 3 0 Tti2 family Vac14_Fab1_bd PF12755.7 EGG20610.1 - 0.042 14.4 1.1 0.15 12.7 0.2 2.4 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region Memo PF01875.17 EGG20610.1 - 0.11 11.6 0.2 0.32 10.1 0.0 1.7 2 0 0 2 2 2 0 Memo-like protein Vac14_Fab1_bd PF12755.7 EGG20611.1 - 3.2e-07 30.8 5.3 4.4e-07 30.4 0.1 4.0 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGG20611.1 - 6.5e-06 26.3 5.1 0.00057 20.0 1.5 4.4 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGG20611.1 - 0.00064 19.3 1.3 0.0041 16.7 1.4 2.3 2 1 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 EGG20611.1 - 0.00076 19.5 2.0 0.094 13.0 0.1 4.8 5 0 0 5 5 5 1 HEAT repeat DUF3730 PF12530.8 EGG20611.1 - 0.001 18.7 1.7 0.0028 17.2 0.3 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3730) RIX1 PF08167.12 EGG20611.1 - 0.0037 17.0 2.5 0.46 10.2 0.1 3.6 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis Tti2 PF10521.9 EGG20611.1 - 0.0037 16.8 8.1 0.25 10.8 0.1 4.1 4 0 0 4 4 4 2 Tti2 family HEAT_2 PF13646.6 EGG20611.1 - 0.044 14.2 0.0 1.4 9.3 0.0 3.4 4 1 1 5 5 5 0 HEAT repeats DUF5584 PF17822.1 EGG20611.1 - 0.085 12.3 2.4 1.6 8.1 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5584) HEAT PF02985.22 EGG20612.1 - 1.3e-05 25.0 0.1 0.23 11.8 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat RIX1 PF08167.12 EGG20612.1 - 5.7e-05 22.9 5.9 0.015 15.0 0.8 5.2 4 2 1 5 5 5 2 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 EGG20612.1 - 0.0044 17.5 0.0 0.032 14.7 0.0 2.6 3 0 0 3 3 3 1 HEAT-like repeat BUD22 PF09073.10 EGG20612.1 - 0.036 13.4 7.0 0.057 12.8 7.0 1.3 1 0 0 1 1 1 0 BUD22 Vac14_Fab1_bd PF12755.7 EGG20612.1 - 0.23 12.1 4.6 0.99 10.0 0.3 3.9 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region DUF1676 PF07898.13 EGG20612.1 - 0.27 11.3 4.6 2 8.4 2.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) V-ATPase_H_C PF11698.8 EGG20612.1 - 0.64 10.2 6.9 2 8.5 0.0 4.2 4 1 0 4 4 4 0 V-ATPase subunit H GOLD_2 PF13897.6 EGG20612.1 - 3.4 8.2 4.9 2 8.9 1.9 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Merozoite_SPAM PF07133.11 EGG20613.1 - 6.8e-05 22.9 22.4 6.8e-05 22.9 22.4 3.0 3 0 0 3 3 3 1 Merozoite surface protein (SPAM) DUF3385 PF11865.8 EGG20613.1 - 0.00022 21.1 9.1 0.17 11.8 0.4 5.3 4 2 2 6 6 6 2 Domain of unknown function (DUF3385) Nop14 PF04147.12 EGG20613.1 - 0.004 15.5 15.0 0.011 14.0 15.0 1.8 1 0 0 1 1 1 1 Nop14-like family CobT PF06213.12 EGG20613.1 - 0.0049 16.3 10.5 0.0082 15.6 10.5 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT HEAT PF02985.22 EGG20613.1 - 0.0098 16.1 2.9 0.037 14.3 0.1 3.5 4 0 0 4 4 2 1 HEAT repeat ZIP4_domain PF18292.1 EGG20613.1 - 0.032 14.1 0.0 0.14 12.1 0.0 2.1 1 1 1 2 2 2 0 Zinc transporter ZIP4 domain Vac14_Fab1_bd PF12755.7 EGG20613.1 - 0.063 13.9 2.9 0.18 12.4 0.1 3.3 4 0 0 4 4 3 0 Vacuolar 14 Fab1-binding region TRAP_alpha PF03896.16 EGG20613.1 - 0.13 11.5 10.4 0.29 10.3 10.4 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PTPRCAP PF15713.5 EGG20613.1 - 0.18 12.1 14.3 0.46 10.8 14.3 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Usp PF00582.26 EGG20613.1 - 0.3 11.6 2.2 0.6 10.6 2.2 1.4 1 0 0 1 1 1 0 Universal stress protein family DUF913 PF06025.12 EGG20613.1 - 0.59 9.1 4.7 0.72 8.8 2.0 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) PI3K_1B_p101 PF10486.9 EGG20613.1 - 0.6 7.8 8.0 1 7.1 8.0 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Tti2 PF10521.9 EGG20613.1 - 0.7 9.4 7.7 10 5.5 0.1 4.8 4 1 1 5 5 5 0 Tti2 family Cnd1 PF12717.7 EGG20613.1 - 0.99 9.4 4.0 1.5 8.9 0.1 3.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 CPSF100_C PF13299.6 EGG20613.1 - 1 9.5 8.8 0.13 12.4 3.7 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal MscS_TM PF12794.7 EGG20613.1 - 2 7.2 4.2 0.82 8.5 0.9 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Tim54 PF11711.8 EGG20613.1 - 2 7.1 10.6 0.013 14.3 2.2 1.5 2 0 0 2 2 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_C37 PF05416.12 EGG20613.1 - 2.8 6.4 4.9 4.4 5.7 4.9 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DNApol_Exo PF18136.1 EGG20613.1 - 4.5 6.3 10.5 5.9 5.9 4.0 2.4 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain FAM176 PF14851.6 EGG20613.1 - 6 6.5 14.5 0.4 10.3 8.8 1.9 2 0 0 2 2 2 0 FAM176 family Vac14_Fab1_bd PF12755.7 EGG20614.1 - 4.4e-08 33.6 0.0 9.3e-07 29.4 0.0 3.1 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGG20614.1 - 1e-06 28.9 0.1 0.00024 21.2 0.0 4.0 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGG20614.1 - 2.1e-06 27.5 0.3 18 5.9 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 EGG20614.1 - 0.0025 18.3 0.0 23 5.6 0.0 4.6 5 0 0 5 5 5 1 HEAT-like repeat CLASP_N PF12348.8 EGG20614.1 - 0.0025 17.4 2.0 0.43 10.1 0.0 3.3 3 1 1 4 4 4 2 CLASP N terminal Tti2 PF10521.9 EGG20614.1 - 5 6.6 7.2 0.4 10.2 0.2 2.7 4 0 0 4 4 4 0 Tti2 family Vac14_Fab1_bd PF12755.7 EGG20615.1 - 0.016 15.8 0.0 0.072 13.7 0.0 2.1 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF2321 PF10083.9 EGG20615.1 - 0.16 11.6 0.0 0.52 9.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Vac14_Fab1_bd PF12755.7 EGG20616.1 - 1.9e-10 41.2 0.7 7.2e-09 36.1 0.1 3.6 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 EGG20616.1 - 0.0036 16.9 8.6 0.16 11.5 0.2 5.3 4 1 1 5 5 5 1 Tti2 family HEAT PF02985.22 EGG20616.1 - 0.0074 16.5 5.4 1.1 9.7 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat DUF3730 PF12530.8 EGG20616.1 - 0.023 14.3 0.1 0.11 12.1 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) HEAT_2 PF13646.6 EGG20616.1 - 0.031 14.7 0.0 1.6 9.2 0.0 3.3 4 0 0 4 4 4 0 HEAT repeats GlutR_dimer PF00745.20 EGG20616.1 - 0.032 14.7 0.1 0.5 10.8 0.1 3.2 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain RIX1 PF08167.12 EGG20616.1 - 0.043 13.6 0.1 1.7 8.3 0.0 2.9 1 1 1 2 2 2 0 rRNA processing/ribosome biogenesis DUF4441 PF14536.6 EGG20617.1 - 0.12 12.5 8.5 1.6 8.9 0.8 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4441) Thioredoxin_8 PF13905.6 EGG20617.1 - 1.5 9.2 4.1 2.8 8.3 1.1 2.4 1 1 1 2 2 2 0 Thioredoxin-like ANAPC15 PF15243.6 EGG20617.1 - 7.4 7.1 18.3 17 5.9 17.6 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 Vac14_Fab1_bd PF12755.7 EGG20618.1 - 2e-10 41.2 7.4 0.00088 19.8 0.2 6.8 6 1 0 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGG20618.1 - 5.8e-06 26.1 11.4 0.0022 18.1 0.2 5.5 5 0 0 5 5 5 2 HEAT repeat RIX1 PF08167.12 EGG20618.1 - 0.00045 20.0 9.5 0.18 11.5 1.3 5.4 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 EGG20618.1 - 0.00095 19.6 2.2 11 6.7 0.0 5.2 6 0 0 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 EGG20618.1 - 0.0024 18.2 0.0 30 5.1 0.0 4.4 3 0 0 3 3 3 0 HEAT repeats Ipi1_N PF12333.8 EGG20618.1 - 0.0086 16.7 2.7 0.28 11.8 0.2 4.2 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation IFRD PF05004.13 EGG20618.1 - 0.024 13.8 4.0 0.016 14.4 0.5 2.6 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) DUF3452 PF11934.8 EGG20618.1 - 0.17 11.4 3.3 0.89 9.1 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) CENP-B_dimeris PF09026.10 EGG20618.1 - 0.59 10.6 17.3 1 9.8 3.9 3.8 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF4637 PF15470.6 EGG20618.1 - 1.1 9.0 6.5 0.55 9.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) UCR_14kD PF02271.16 EGG20619.1 - 0.092 12.7 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF1281 PF06924.11 EGG20619.1 - 0.097 12.2 0.2 0.12 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF3452 PF11934.8 EGG20620.1 - 0.03 13.9 0.1 0.061 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF3298 PF11738.8 EGG20620.1 - 4.9 8.3 6.1 1.9 9.6 1.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3298) Tti2 PF10521.9 EGG20621.1 - 6.6e-08 32.4 4.9 0.0002 21.0 0.3 4.1 3 1 0 3 3 3 2 Tti2 family Vac14_Fab1_bd PF12755.7 EGG20621.1 - 9.9e-08 32.5 0.2 0.0035 17.9 0.0 3.9 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGG20621.1 - 7.6e-05 22.6 0.5 0.49 10.8 0.1 5.8 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 EGG20621.1 - 0.00028 21.2 0.0 3.7 8.0 0.0 4.3 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 EGG20621.1 - 0.022 15.2 1.5 1.7 9.2 0.1 4.0 5 0 0 5 5 5 0 HEAT-like repeat RTP1_C1 PF10363.9 EGG20621.1 - 0.13 12.5 1.3 17 5.7 0.1 3.4 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 EGG20624.1 - 0.00063 20.3 0.2 0.0063 17.1 0.1 2.9 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGG20624.1 - 0.015 15.5 0.4 0.17 12.2 0.1 2.9 3 0 0 3 3 3 0 HEAT repeat DNA_pol_phi PF04931.13 EGG20624.1 - 7.5 4.5 12.9 6.8 4.7 0.2 2.4 2 0 0 2 2 2 0 DNA polymerase phi HEAT PF02985.22 EGG20625.1 - 9.7e-12 44.1 8.3 0.051 13.9 0.0 11.2 13 0 0 13 13 13 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EGG20625.1 - 3.6e-06 27.5 7.6 0.02 15.5 0.4 5.6 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGG20625.1 - 3.4e-05 23.9 17.5 0.039 14.0 0.3 8.2 6 2 2 8 8 8 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EGG20625.1 - 0.27 11.4 2.3 10 6.4 0.0 4.8 4 1 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3452 PF11934.8 EGG20626.1 - 0.0045 16.5 0.1 0.0095 15.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3452) DUF4023 PF13215.6 EGG20626.1 - 0.0079 16.2 3.1 0.74 9.9 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4023) Cnd1 PF12717.7 EGG20627.1 - 5.3e-11 42.8 3.1 1e-09 38.6 1.2 3.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGG20627.1 - 3.7e-09 37.1 0.1 6.5e-05 23.5 0.6 3.4 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGG20627.1 - 7.9e-09 35.0 3.3 0.24 11.8 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 EGG20627.1 - 8.6e-08 32.5 0.0 0.028 14.8 0.0 3.9 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EGG20627.1 - 1e-07 32.3 0.0 0.036 14.6 0.0 3.3 3 0 0 3 3 3 2 HEAT-like repeat CLASP_N PF12348.8 EGG20627.1 - 0.045 13.3 5.5 0.48 10.0 0.9 3.3 3 1 0 3 3 3 0 CLASP N terminal HEAT PF02985.22 EGG20628.1 - 7e-14 50.8 6.0 0.0023 18.0 0.1 10.1 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.7 EGG20628.1 - 1.4e-10 41.6 10.7 0.00032 21.2 0.3 5.7 4 0 0 4 4 4 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGG20628.1 - 1.5e-06 28.6 0.1 0.073 13.6 0.0 4.8 6 0 0 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 EGG20628.1 - 1.6e-06 28.4 0.0 5.6 7.4 0.0 5.6 4 1 0 4 4 4 3 HEAT repeats Cnd1 PF12717.7 EGG20628.1 - 2.4e-06 27.7 0.9 2.4e-06 27.7 0.9 6.7 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 EGG20628.1 - 0.022 14.3 19.6 0.38 10.2 0.7 8.6 9 1 0 9 9 9 0 Tti2 family RTP1_C1 PF10363.9 EGG20628.1 - 0.034 14.3 1.6 14 5.9 0.1 4.9 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4358 PF14270.6 EGG20628.1 - 0.11 12.8 13.9 0.031 14.6 1.3 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4358) DUF3452 PF11934.8 EGG20628.1 - 0.59 9.7 18.9 0.7 9.4 0.2 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF3452) PQ-loop PF04193.14 EGG20629.1 - 7.9e-17 60.8 8.5 1.4e-15 56.8 1.1 3.6 4 0 0 4 4 4 2 PQ loop repeat EGF_2 PF07974.13 EGG20629.1 - 0.011 16.1 13.0 0.022 15.1 13.0 1.6 1 0 0 1 1 1 0 EGF-like domain Podoplanin PF05808.11 EGG20629.1 - 0.083 13.0 0.2 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 Podoplanin HEAT PF02985.22 EGG20630.1 - 2.7e-10 39.6 0.4 0.0091 16.2 0.1 5.1 4 0 0 4 4 4 2 HEAT repeat Vac14_Fab1_bd PF12755.7 EGG20630.1 - 6.8e-10 39.4 0.8 8.3e-05 23.1 0.2 4.9 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGG20630.1 - 7.8e-07 29.5 0.0 0.047 14.2 0.0 4.1 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 EGG20630.1 - 8.3e-07 29.3 0.0 0.047 14.1 0.0 3.9 5 1 0 5 5 5 2 HEAT repeats Tti2 PF10521.9 EGG20630.1 - 0.00025 20.7 12.7 0.081 12.4 0.2 5.0 4 2 0 4 4 4 2 Tti2 family DUF1543 PF07566.12 EGG20630.1 - 0.041 13.6 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) DNA_alkylation PF08713.11 EGG20630.1 - 0.1 12.3 0.1 0.37 10.5 0.1 2.0 1 0 0 1 1 1 0 DNA alkylation repair enzyme Ipi1_N PF12333.8 EGG20630.1 - 1.5 9.5 4.3 11 6.7 0.2 4.1 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 EGG20631.1 - 3.4e-05 23.7 5.3 0.12 12.7 0.1 5.5 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EGG20631.1 - 0.00022 21.3 7.7 0.00046 20.3 1.9 3.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 EGG20631.1 - 0.0011 18.6 1.3 0.38 10.2 0.2 3.3 2 0 0 2 2 2 2 Tti2 family HEAT_2 PF13646.6 EGG20631.1 - 0.0014 18.9 0.0 0.62 10.5 0.0 3.9 4 0 0 4 4 4 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EGG20631.1 - 0.0047 17.5 1.4 0.23 12.1 0.4 3.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGG20631.1 - 0.024 15.2 0.1 0.46 11.0 0.0 3.1 3 0 0 3 3 3 0 HEAT-like repeat Methylase_S PF01420.19 EGG20631.1 - 0.028 14.6 0.5 0.028 14.6 0.5 2.6 2 0 0 2 2 2 0 Type I restriction modification DNA specificity domain RIH_assoc PF08454.11 EGG20631.1 - 1 9.2 13.0 0.18 11.7 0.1 5.0 4 1 2 6 6 6 0 RyR and IP3R Homology associated HEAT PF02985.22 EGG20633.1 - 3.7e-07 29.8 1.4 0.028 14.7 0.0 6.9 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 EGG20633.1 - 2.1e-05 24.8 0.0 0.0015 18.8 0.0 3.8 4 0 0 4 4 4 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EGG20633.1 - 0.00038 21.0 1.3 0.0069 17.0 0.2 3.8 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EGG20633.1 - 0.45 10.7 3.9 7.4 6.8 1.0 4.1 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF2321 PF10083.9 EGG20633.1 - 0.95 9.1 3.9 16 5.1 0.3 3.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2321) Importin_rep_5 PF18816.1 EGG20633.1 - 6.2 7.2 6.6 46 4.4 0.1 4.0 4 0 0 4 4 4 0 Importin repeat HEAT PF02985.22 EGG20634.1 - 6.8e-12 44.6 4.7 0.018 15.2 0.2 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 EGG20634.1 - 1.2e-06 28.8 0.1 0.097 13.1 0.1 4.2 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EGG20634.1 - 0.00017 22.0 0.9 2.9 8.5 0.0 6.0 6 0 0 6 6 6 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGG20634.1 - 0.0018 18.8 16.8 0.25 12.0 0.1 6.6 8 0 0 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGG20634.1 - 0.011 15.8 23.7 0.39 10.8 0.0 6.4 7 2 2 9 9 9 0 non-SMC mitotic condensation complex subunit 1 CPL PF08144.11 EGG20634.1 - 0.11 12.9 1.4 1.3 9.4 0.3 3.4 2 1 0 2 2 2 0 CPL (NUC119) domain RTP1_C1 PF10363.9 EGG20634.1 - 0.79 9.9 7.8 3 8.1 0.1 5.0 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 EGG20635.1 - 0.00022 21.3 3.5 0.0037 17.3 0.4 3.2 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGG20635.1 - 0.0012 18.9 2.0 3.7 8.1 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat Vac14_Fab1_bd PF12755.7 EGG20635.1 - 0.0044 17.6 0.3 0.019 15.5 0.1 2.2 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGG20636.1 - 2.2e-09 36.8 7.8 0.052 13.8 0.1 7.5 7 0 0 7 7 6 2 HEAT repeat Tti2 PF10521.9 EGG20636.1 - 6.6e-05 22.6 9.1 0.0029 17.2 0.1 4.5 5 0 0 5 5 5 2 Tti2 family HEAT_EZ PF13513.6 EGG20636.1 - 8.2e-05 23.0 2.6 50 4.5 0.0 7.1 8 0 0 8 8 8 0 HEAT-like repeat CLASP_N PF12348.8 EGG20636.1 - 0.0001 22.0 9.6 0.054 13.1 0.0 4.8 3 1 1 4 4 4 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 EGG20636.1 - 0.00061 20.3 2.5 1.9 9.1 0.1 4.9 5 0 0 5 5 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EGG20636.1 - 0.0034 17.7 0.0 15 6.0 0.0 5.0 6 0 0 6 6 5 0 HEAT repeats IBN_N PF03810.19 EGG20636.1 - 0.0038 17.1 1.2 0.67 9.9 0.0 4.8 4 0 0 4 4 3 1 Importin-beta N-terminal domain RRN3 PF05327.11 EGG20636.1 - 0.012 14.2 8.9 0.0067 15.0 6.5 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Cnd1 PF12717.7 EGG20636.1 - 0.012 15.7 26.4 0.33 11.0 0.6 7.7 7 3 2 9 9 9 0 non-SMC mitotic condensation complex subunit 1 SpoIIP PF07454.11 EGG20636.1 - 0.27 10.7 2.5 0.61 9.5 2.5 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) BUD22 PF09073.10 EGG20636.1 - 0.85 8.9 9.3 1.4 8.2 9.3 1.2 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 EGG20636.1 - 0.89 9.4 17.2 0.22 11.4 12.6 2.4 3 0 0 3 3 3 0 Sigma-70, non-essential region TRAP_alpha PF03896.16 EGG20636.1 - 2.9 7.0 8.2 5.3 6.2 8.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.10 EGG20636.1 - 3.4 8.1 28.0 1.5 9.2 24.5 2.4 2 0 0 2 2 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 EGG20636.1 - 3.5 7.3 8.8 8.6 6.0 8.8 1.6 1 0 0 1 1 1 0 FAM176 family FANCI_S2 PF14676.6 EGG20637.1 - 0.00039 20.7 0.1 0.00045 20.6 0.1 1.1 1 0 0 1 1 1 1 FANCI solenoid 2 V-ATPase_H_N PF03224.14 EGG20637.1 - 0.015 14.6 0.5 0.041 13.2 0.5 1.5 1 1 0 1 1 1 0 V-ATPase subunit H HEAT PF02985.22 EGG20639.1 - 1.2e-07 31.4 0.1 1 9.8 0.1 5.4 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 EGG20639.1 - 3.7e-07 30.5 0.0 0.16 12.5 0.0 4.9 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 EGG20639.1 - 7.4e-06 26.1 13.2 0.032 14.3 0.3 6.6 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGG20639.1 - 2.4e-05 24.8 6.6 1.2 9.7 0.1 5.7 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 EGG20639.1 - 0.048 13.2 9.9 1.1 8.7 0.1 5.7 6 0 0 6 6 6 0 Tti2 family CARD_2 PF16739.5 EGG20639.1 - 0.1 12.6 0.1 0.74 9.8 0.0 2.6 2 0 0 2 2 2 0 Caspase recruitment domain PPP5 PF08321.12 EGG20639.1 - 0.17 12.2 1.8 0.87 9.9 0.2 3.1 3 0 0 3 3 3 0 PPP5 TPR repeat region BP28CT PF08146.12 EGG20639.1 - 0.3 10.9 6.1 3.8 7.3 0.1 4.7 4 1 0 4 4 4 0 BP28CT (NUC211) domain CRM1_repeat_3 PF18787.1 EGG20639.1 - 0.38 10.9 1.7 3.2 7.9 0.2 3.0 2 0 0 2 2 2 0 CRM1 / Exportin repeat 3 RIX1 PF08167.12 EGG20639.1 - 3.2 7.4 10.2 17 5.1 0.0 5.6 6 0 0 6 6 6 0 rRNA processing/ribosome biogenesis HEAT PF02985.22 EGG20640.1 - 9.8e-11 41.0 4.4 0.11 12.8 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EGG20640.1 - 3.7e-09 37.1 1.0 0.002 18.7 0.2 5.1 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGG20640.1 - 8e-06 26.2 0.1 3.2 8.3 0.0 4.7 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 EGG20640.1 - 1.2e-05 25.6 0.0 2.4 8.6 0.0 5.2 5 1 2 7 7 7 2 HEAT repeats Cnd1 PF12717.7 EGG20640.1 - 1.8e-05 24.8 10.1 0.055 13.5 0.1 5.5 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EGG20640.1 - 0.0012 19.0 1.9 2.8 8.1 0.0 4.3 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 EGG20640.1 - 0.0081 15.3 0.5 0.66 9.0 0.0 3.4 3 0 0 3 3 3 1 Interferon-related developmental regulator (IFRD) Cohesin_HEAT PF12765.7 EGG20640.1 - 0.036 14.4 0.0 0.22 11.9 0.0 2.5 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion PhoLip_ATPase_C PF16212.5 EGG20641.1 - 2.3 7.9 33.4 0.32 10.7 21.4 2.3 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal FNIP PF05725.12 EGG20642.1 - 2.6e-52 174.7 16.6 8.2e-12 45.1 0.1 8.4 4 2 3 8 8 8 8 FNIP Repeat DUF1769 PF08588.10 EGG20642.1 - 0.0025 18.0 5.0 15 5.9 0.1 5.8 4 2 2 6 6 6 2 Protein of unknown function (DUF1769) FNIP PF05725.12 EGG20643.1 - 3.2e-37 126.4 34.2 6.7e-09 35.8 0.1 8.4 3 2 8 11 11 11 11 FNIP Repeat DUF1769 PF08588.10 EGG20643.1 - 0.027 14.7 0.4 6.8 7.0 0.0 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF1769) RhoGAP PF00620.27 EGG20645.1 - 2.9e-35 121.3 0.0 4.2e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Reg_prop PF07494.11 EGG20645.1 - 0.0046 17.0 0.1 3.5 8.2 0.0 3.8 3 0 0 3 3 3 1 Two component regulator propeller WD40 PF00400.32 EGG20645.1 - 0.015 16.1 4.3 24 6.0 0.0 5.1 5 0 0 5 5 5 0 WD domain, G-beta repeat PQQ_3 PF13570.6 EGG20645.1 - 0.078 13.5 0.1 2 9.0 0.0 3.3 5 0 0 5 5 5 0 PQQ-like domain NPR3 PF03666.13 EGG20646.1 - 0.0017 17.2 1.2 0.0017 17.2 1.2 2.1 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Pet100 PF09803.9 EGG20646.1 - 0.016 15.7 1.9 0.016 15.7 1.9 2.0 2 0 0 2 2 2 0 Pet100 DUF2189 PF09955.9 EGG20646.1 - 0.031 14.5 1.8 1.8 8.8 0.4 2.8 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2189) U1snRNP70_N PF12220.8 EGG20646.1 - 0.033 14.8 0.5 0.033 14.8 0.5 2.8 2 1 0 2 2 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Renin_r PF07850.14 EGG20646.1 - 0.04 14.5 6.3 1.3 9.6 0.0 2.9 2 1 0 2 2 2 0 Renin receptor-like protein CLN3 PF02487.17 EGG20646.1 - 0.12 11.4 4.2 2.2 7.2 2.4 2.3 2 0 0 2 2 2 0 CLN3 protein DUF3464 PF11947.8 EGG20646.1 - 0.16 11.7 0.1 0.16 11.7 0.1 3.1 2 1 0 2 2 1 0 Photosynthesis affected mutant 68 LAP1C PF05609.12 EGG20646.1 - 0.16 11.0 13.1 0.38 9.8 0.5 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Peroxin-13_N PF04088.13 EGG20646.1 - 0.17 12.1 5.2 14 6.0 0.0 2.8 2 1 0 2 2 2 0 Peroxin 13, N-terminal region FAM60A PF15396.6 EGG20646.1 - 0.6 10.1 8.5 0.9 9.5 1.7 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Plasmodium_Vir PF05795.11 EGG20646.1 - 0.72 9.2 12.5 0.12 11.7 6.6 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein MSC PF09402.10 EGG20646.1 - 1.5 8.2 7.9 2.7 7.4 2.5 2.3 2 1 0 2 2 2 0 Man1-Src1p-C-terminal domain CNDH2_C PF16858.5 EGG20646.1 - 9 6.1 16.2 4.6 7.0 2.9 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Neur_chan_memb PF02932.16 EGG20646.1 - 9.7 6.2 7.6 97 2.9 6.7 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region HHH_2 PF12826.7 EGG20647.1 - 0.00061 19.8 0.0 0.0015 18.6 0.0 1.6 1 1 0 1 1 1 1 Helix-hairpin-helix motif Clathrin PF00637.20 EGG20648.1 - 1.2e-197 647.7 47.5 4.5e-32 110.9 0.5 8.6 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EGG20648.1 - 1.1e-27 95.0 2.2 1.6e-06 28.2 0.3 5.0 5 0 0 5 5 4 4 Clathrin propeller repeat Clathrin_H_link PF13838.6 EGG20648.1 - 7.2e-27 93.1 3.6 7.8e-27 93.0 0.4 2.9 4 0 0 4 4 4 1 Clathrin-H-link Clathrin-link PF09268.10 EGG20648.1 - 9.3e-11 40.9 0.1 3.3e-10 39.1 0.1 2.1 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_7 PF13176.6 EGG20648.1 - 1.5e-06 27.8 3.3 0.78 9.9 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EGG20648.1 - 9e-06 25.0 2.1 0.16 11.0 0.0 3.9 4 0 0 4 4 4 2 Coatomer WD associated region TPR_1 PF00515.28 EGG20648.1 - 6.7e-05 22.5 9.6 0.25 11.2 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG20648.1 - 0.00027 20.9 9.0 0.75 10.2 0.0 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG20648.1 - 0.00033 20.6 11.9 0.51 10.6 0.1 7.5 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG20648.1 - 0.00074 19.8 1.5 7.5 6.9 0.1 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG20648.1 - 0.016 16.0 10.9 50 5.1 0.4 8.4 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG20648.1 - 3.8 8.3 5.8 77 4.2 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Tom37 PF10568.9 EGG20648.1 - 4.5 7.6 5.5 4.5 7.6 0.6 3.3 3 0 0 3 3 3 0 Outer mitochondrial membrane transport complex protein Clathrin_propel PF01394.20 EGG20649.1 - 5.6e-11 42.2 0.1 1.5e-06 28.2 0.1 2.3 2 1 0 2 2 2 2 Clathrin propeller repeat LVIVD PF08309.11 EGG20649.1 - 0.064 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 LVIVD repeat ubiquitin PF00240.23 EGG20650.1 - 8.6e-12 44.6 0.6 1.1e-11 44.4 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGG20650.1 - 1.4e-06 28.1 1.0 1.6e-06 27.8 1.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGG20650.1 - 0.00032 21.2 0.0 0.00034 21.1 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGG20650.1 - 0.0026 17.9 0.1 0.0037 17.4 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TmoB PF06234.12 EGG20650.1 - 0.048 13.7 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) DUF4460 PF14687.6 EGG20651.1 - 1.3e-06 28.4 2.2 1.3e-06 28.4 2.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4460) Voltage_CLC PF00654.20 EGG20653.1 - 0.0021 17.4 0.0 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel Cas_CXXC_CXXC PF09706.10 EGG20653.1 - 0.052 13.8 0.2 0.075 13.3 0.2 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) Voltage_CLC PF00654.20 EGG20654.1 - 4.5e-91 305.7 22.9 4.5e-91 305.7 22.9 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel XhlA PF10779.9 EGG20654.1 - 0.014 15.6 2.3 0.039 14.2 0.1 2.8 2 0 0 2 2 2 0 Haemolysin XhlA TAT_signal PF10518.9 EGG20654.1 - 0.84 9.6 5.8 0.17 11.8 0.4 2.3 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence DUF373 PF04123.13 EGG20654.1 - 1.3 8.4 18.5 1.8 7.9 10.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF373) CBS PF00571.28 EGG20655.1 - 5.9e-07 29.8 0.1 1.1e-05 25.8 0.0 2.3 2 0 0 2 2 2 1 CBS domain IN_DBD_C PF00552.21 EGG20656.1 - 0.0021 17.3 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Integrase DNA binding domain B_lectin PF01453.24 EGG20656.1 - 0.0057 17.2 0.0 0.0095 16.5 0.0 1.5 1 1 0 1 1 1 1 D-mannose binding lectin RNA_lig_T4_1 PF09511.10 EGG20656.1 - 0.087 12.7 0.0 0.087 12.7 0.0 1.3 1 1 0 1 1 1 0 RNA ligase LRR_8 PF13855.6 EGG20657.1 - 9e-05 22.2 19.4 0.18 11.6 0.0 8.8 10 0 0 10 10 10 3 Leucine rich repeat PDZ PF00595.24 EGG20657.1 - 0.0036 17.6 0.0 3.9 7.9 0.0 2.6 2 0 0 2 2 2 2 PDZ domain IRK_N PF08466.10 EGG20657.1 - 0.017 15.2 3.0 6.6 7.0 0.2 3.4 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal HlyD_2 PF12700.7 EGG20657.1 - 0.037 12.8 7.5 1 8.0 0.9 2.3 2 0 0 2 2 2 0 HlyD family secretion protein Polyhedrin PF00738.18 EGG20657.1 - 0.046 13.1 0.2 7.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Polyhedrin EGF_2 PF07974.13 EGG20657.1 - 0.054 13.9 67.4 0.26 11.7 8.2 4.8 4 0 0 4 4 4 0 EGF-like domain BTB_2 PF02214.22 EGG20657.1 - 0.12 12.8 0.1 30 5.0 0.0 3.1 2 0 0 2 2 2 0 BTB/POZ domain Glucosamine_iso PF01182.20 EGG20658.1 - 1e-42 146.6 0.0 1.2e-42 146.4 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CarboxypepD_reg PF13620.6 EGG20659.1 - 5.1e-49 164.5 10.1 4.5e-08 33.3 0.0 10.3 10 0 0 10 10 10 8 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 EGG20659.1 - 2.9e-23 82.2 17.4 6.5e-05 23.1 0.0 9.3 10 0 0 10 10 10 6 SdrD B-like domain CarbopepD_reg_2 PF13715.6 EGG20659.1 - 3.3e-20 71.9 19.4 3.8e-07 30.0 0.3 9.7 9 0 0 9 9 9 5 CarboxypepD_reg-like domain DUF2012 PF09430.10 EGG20659.1 - 4.2e-17 62.4 1.4 0.16 12.1 0.0 8.8 6 2 2 8 8 8 3 Protein of unknown function (DUF2012) SpaA PF17802.1 EGG20659.1 - 2.8e-10 40.4 6.4 0.077 13.3 0.0 7.5 6 2 2 8 8 8 2 Prealbumin-like fold domain DUF2846 PF11008.8 EGG20659.1 - 1.2e-08 34.8 2.2 4.9e-05 23.3 0.1 6.0 8 0 0 8 8 7 1 Protein of unknown function (DUF2846) fn3_3 PF14686.6 EGG20659.1 - 1.7e-05 24.5 0.3 0.69 9.7 0.0 5.1 5 0 0 5 5 5 1 Polysaccharide lyase family 4, domain II phage_tail_N PF08400.10 EGG20659.1 - 0.00012 22.1 0.1 3.4 7.7 0.0 3.9 3 0 0 3 3 3 1 Prophage tail fibre N-terminal bMG3 PF11974.8 EGG20659.1 - 0.00013 22.0 0.4 0.27 11.3 0.0 3.8 3 0 0 3 3 3 1 Bacterial alpha-2-macroglobulin MG3 domain Y_Y_Y PF07495.13 EGG20659.1 - 0.00021 21.2 0.8 3.3 7.7 0.0 4.8 4 0 0 4 4 4 1 Y_Y_Y domain fn3 PF00041.21 EGG20659.1 - 0.00076 19.8 3.8 0.088 13.2 0.0 5.1 5 0 0 5 5 5 1 Fibronectin type III domain Wzt_C PF14524.6 EGG20659.1 - 0.022 14.8 0.5 4.8 7.2 0.0 3.4 4 0 0 4 4 3 0 Wzt C-terminal domain HepII_C PF18675.1 EGG20659.1 - 0.025 14.6 0.1 0.92 9.6 0.0 3.6 3 0 0 3 3 3 0 Heparinase II C-terminal domain MetallophosN PF16371.5 EGG20659.1 - 0.047 14.0 6.2 0.89 9.9 0.2 5.0 6 0 0 6 6 6 0 N terminal of Calcineurin-like phosphoesterase CppA_N PF14506.6 EGG20659.1 - 0.082 13.0 0.1 0.92 9.6 0.0 2.5 2 0 0 2 2 2 0 CppA N-terminal CS PF04969.16 EGG20659.1 - 0.25 12.4 3.2 14 6.8 0.2 4.4 3 0 0 3 3 3 0 CS domain MaoC_dehydratas PF01575.19 EGG20660.1 - 3.7e-30 104.0 0.0 7.3e-29 99.8 0.0 2.1 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EGG20660.1 - 4.4e-07 30.1 0.0 0.00011 22.4 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Trypsin_2 PF13365.6 EGG20661.1 - 0.00049 21.0 0.0 0.00079 20.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain ABC1 PF03109.16 EGG20662.1 - 4e-31 107.6 0.0 7.3e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family EGF_2 PF07974.13 EGG20663.1 - 0.038 14.4 12.4 0.095 13.1 12.4 1.8 1 0 0 1 1 1 0 EGF-like domain LRR_8 PF13855.6 EGG20663.1 - 0.11 12.3 6.8 0.79 9.5 0.3 3.4 3 0 0 3 3 3 0 Leucine rich repeat DUF3844 PF12955.7 EGG20663.1 - 5.3 7.2 8.6 22 5.3 8.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3844) dCMP_cyt_deam_1 PF00383.23 EGG20664.1 - 1.2e-19 70.1 5.0 1.5e-18 66.5 5.0 2.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGG20664.1 - 1.9e-18 66.5 12.3 5.1e-10 39.3 0.1 2.9 1 1 1 3 3 3 2 MafB19-like deaminase RWD PF05773.22 EGG20664.1 - 0.0098 16.2 0.1 0.026 14.8 0.1 1.7 1 0 0 1 1 1 1 RWD domain SNAD4 PF18750.1 EGG20664.1 - 0.81 9.8 8.1 0.25 11.5 0.5 2.7 2 1 1 3 3 3 0 Secreted Novel AID/APOBEC-like Deaminase 4 DUF3439 PF11921.8 EGG20664.1 - 1 9.3 17.0 4 7.4 10.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Bd3614-deam PF14439.6 EGG20664.1 - 2.2 8.3 19.6 0.52 10.4 4.0 2.6 1 1 1 2 2 2 0 Bd3614-like deaminase ATP11 PF06644.11 EGG20664.1 - 7.7 6.2 12.4 18 5.0 0.3 3.0 3 0 0 3 3 3 0 ATP11 protein CBS PF00571.28 EGG20665.1 - 2.2e-25 88.8 2.6 1.7e-14 54.0 1.4 2.5 2 0 0 2 2 2 2 CBS domain DisA_N PF02457.16 EGG20665.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding FNIP PF05725.12 EGG20666.1 - 0.45 10.7 14.4 2.1 8.6 0.0 5.4 5 2 0 5 5 5 0 FNIP Repeat Macoilin PF09726.9 EGG20667.1 - 0.07 11.7 34.9 0.086 11.4 34.9 1.2 1 0 0 1 1 1 0 Macoilin family Borrelia_P83 PF05262.11 EGG20667.1 - 0.26 9.7 57.0 0.34 9.4 57.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Mitofilin PF09731.9 EGG20667.1 - 0.77 8.5 44.8 1.1 8.0 44.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LAP1C PF05609.12 EGG20667.1 - 1.4 7.9 33.8 1.9 7.5 33.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF936 PF06075.12 EGG20667.1 - 5.9 5.7 41.9 8 5.2 41.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF3402 PF11882.8 EGG20668.1 - 2e-48 165.6 25.1 1.1e-32 113.7 5.9 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF3402) N1221 PF07923.13 EGG20668.1 - 1.4e-22 80.2 2.4 1.4e-22 80.2 2.4 2.0 2 0 0 2 2 2 1 N1221-like protein DUF3242 PF11586.8 EGG20669.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) VIT1 PF01988.19 EGG20669.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 VIT family DUF1569 PF07606.11 EGG20669.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) 1-cysPrx_C PF10417.9 EGG20671.1 - 0.086 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin Kelch_1 PF01344.25 EGG20672.1 - 7.7e-32 108.6 7.3 3.1e-14 52.3 0.7 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 EGG20672.1 - 2.9e-23 81.3 0.7 3.5e-09 36.6 0.2 4.8 2 1 2 4 4 4 4 Kelch motif Kelch_2 PF07646.15 EGG20672.1 - 1.9e-12 46.6 0.6 0.0052 16.7 0.1 5.1 4 1 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EGG20672.1 - 2.3e-10 40.3 0.2 0.00023 21.1 0.0 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG20672.1 - 1.4e-09 37.7 3.6 1.2e-06 28.4 0.0 3.6 4 0 0 4 4 4 2 Kelch motif BTB_2 PF02214.22 EGG20672.1 - 3.6e-08 33.7 0.0 1.5e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 EGG20672.1 - 5.5e-06 26.5 5.2 1.3 9.3 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain BTB_3 PF16017.5 EGG20672.1 - 0.035 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 BTB/POZ domain Kelch_5 PF13854.6 EGG20673.1 - 0.031 14.3 0.4 0.098 12.7 0.1 2.0 2 0 0 2 2 2 0 Kelch motif RhoGEF PF00621.20 EGG20674.1 - 7.2e-42 143.7 1.9 2.6e-41 141.8 1.9 2.0 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 EGG20674.1 - 0.00065 19.7 0.4 0.0031 17.5 0.4 2.1 1 0 0 1 1 1 1 PH domain IQ PF00612.27 EGG20674.1 - 0.0012 18.5 1.6 0.0027 17.4 1.6 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH_13 PF16652.5 EGG20674.1 - 0.0031 17.3 1.7 0.0088 15.9 1.7 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_10 PF15411.6 EGG20674.1 - 0.004 17.4 0.3 0.004 17.4 0.3 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain RNA_pol_Rpb1_3 PF04983.18 EGG20674.1 - 0.036 14.0 0.0 0.16 11.9 0.0 2.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 DUF1664 PF07889.12 EGG20674.1 - 0.12 12.4 1.5 0.27 11.3 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PH PF00169.29 EGG20674.1 - 0.16 12.5 4.4 1.1 9.9 4.4 2.3 1 1 0 1 1 1 0 PH domain CCDC53 PF10152.9 EGG20674.1 - 1.8 8.9 10.4 0.16 12.4 2.5 2.9 3 1 0 3 3 3 0 Subunit CCDC53 of WASH complex PT PF04886.12 EGG20675.1 - 0.042 13.4 0.6 0.064 12.8 0.6 1.3 1 0 0 1 1 1 0 PT repeat HpcH_HpaI PF03328.14 EGG20677.1 - 4.9e-44 150.1 0.4 1.1e-43 148.9 0.4 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EGG20677.1 - 5.3e-16 58.7 0.2 1.3e-11 44.3 0.2 2.2 1 1 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold AIG1 PF04548.16 EGG20678.1 - 9.9e-09 34.8 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 EGG20678.1 - 1.2e-06 28.6 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGG20678.1 - 0.00031 20.2 0.1 0.00057 19.3 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Sigma54_activat PF00158.26 EGG20678.1 - 0.00036 20.3 0.0 0.0006 19.6 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 EGG20678.1 - 0.0021 17.6 0.1 0.0038 16.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 EGG20678.1 - 0.0028 18.2 0.6 0.0063 17.0 0.2 1.7 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EGG20678.1 - 0.0028 17.6 0.0 0.0065 16.4 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 EGG20678.1 - 0.0033 16.8 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.6 EGG20678.1 - 0.016 14.9 0.1 0.033 13.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EGG20678.1 - 0.019 14.1 0.4 0.073 12.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain T2SSE PF00437.20 EGG20678.1 - 0.02 13.9 0.1 0.034 13.2 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Septin PF00735.18 EGG20678.1 - 0.025 13.9 0.2 0.088 12.1 0.2 1.9 1 1 0 1 1 1 0 Septin Alba PF01918.21 EGG20678.1 - 0.026 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Alba AAA_23 PF13476.6 EGG20678.1 - 0.038 14.5 1.6 0.064 13.8 0.4 1.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGG20678.1 - 0.05 13.7 0.1 0.099 12.7 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 EGG20678.1 - 0.093 12.4 0.1 0.55 9.9 0.0 1.9 1 1 1 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 EGG20678.1 - 0.2 11.9 0.2 0.4 11.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 EGG20678.1 - 0.26 10.4 1.4 0.54 9.4 1.4 1.9 1 1 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.6 EGG20678.1 - 0.55 10.8 2.3 0.95 10.0 1.9 1.8 1 1 1 2 2 2 0 AAA domain FNIP PF05725.12 EGG20679.1 - 2.2e-211 683.9 95.6 4.7e-16 58.7 0.8 12.2 3 1 16 19 19 19 19 FNIP Repeat Pkinase PF00069.25 EGG20679.1 - 7.2e-18 64.9 0.4 1.7e-17 63.7 0.3 1.6 1 1 1 2 2 2 1 Protein kinase domain Phage_min_tail PF05939.13 EGG20679.1 - 1.2e-09 38.5 11.0 9.7 6.6 0.0 10.9 5 4 7 12 12 12 1 Phage minor tail protein Pkinase_Tyr PF07714.17 EGG20679.1 - 0.0028 17.0 0.0 0.41 9.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DUF5536 PF17688.1 EGG20679.1 - 1.7 8.5 3.7 57 3.5 0.0 3.9 4 0 0 4 4 4 0 Family of unknown function (DUF5536) RdRP PF05183.12 EGG20680.1 - 9.4e-132 440.6 0.0 1.8e-131 439.7 0.0 1.5 1 0 0 1 1 1 1 RNA dependent RNA polymerase Helicase_C PF00271.31 EGG20680.1 - 3.4e-19 69.2 0.3 1.2e-18 67.5 0.3 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG20680.1 - 8.7e-12 45.4 0.0 5.1e-11 42.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG20680.1 - 4.9e-09 36.2 0.0 1.9e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Spidroin_N PF16763.5 EGG20680.1 - 0.064 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term Nop16 PF09420.10 EGG20681.1 - 1.6e-09 38.1 7.5 1e-07 32.2 0.2 4.3 4 1 0 5 5 5 2 Ribosome biogenesis protein Nop16 Mucin PF01456.17 EGG20681.1 - 0.053 13.5 23.1 0.12 12.4 23.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein TetR_C_21 PF17926.1 EGG20681.1 - 1.6 8.9 6.7 3.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF2252 PF10009.9 EGG20681.1 - 5.9 5.8 8.5 10 5.1 8.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) WD40 PF00400.32 EGG20682.1 - 1.3e-16 60.6 8.4 7.3e-06 26.6 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG20682.1 - 3.6e-10 40.0 0.0 0.01 16.1 0.0 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_Mx1 PF15890.5 EGG20682.1 - 0.0019 17.7 0.0 1 8.8 0.0 2.1 2 0 0 2 2 2 2 Putative zinc-binding metallo-peptidase Ge1_WD40 PF16529.5 EGG20682.1 - 0.0056 15.7 0.0 0.19 10.7 0.0 2.4 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EGG20682.1 - 0.0058 15.0 0.0 0.053 11.8 0.0 1.9 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Methyltransf_13 PF08421.11 EGG20682.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative zinc binding domain Actin PF00022.19 EGG20683.1 - 6.6e-95 318.1 0.0 8.8e-94 314.4 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGG20683.1 - 8.9e-06 24.7 0.0 2.3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 EGG20683.1 - 0.013 14.6 0.0 3 6.8 0.0 2.3 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Copine PF07002.16 EGG20684.1 - 7e-55 185.8 0.0 1e-54 185.3 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGG20684.1 - 5e-25 87.8 0.1 3.4e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGG20684.1 - 8.4e-05 22.8 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF3993 PF13158.6 EGG20684.1 - 0.058 13.6 0.0 16 5.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) TFIIA PF03153.13 EGG20686.1 - 0.0025 17.9 12.2 0.0025 17.9 12.2 6.3 5 1 1 7 7 7 2 Transcription factor IIA, alpha/beta subunit AAA_16 PF13191.6 EGG20686.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Nup54 PF13874.6 EGG20687.1 - 4.5e-27 94.9 2.1 4.5e-27 94.9 2.1 2.7 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 EGG20687.1 - 0.00028 21.7 31.8 0.00028 21.7 31.8 3.4 1 1 2 3 3 3 2 Nucleoporin FG repeat region AvrM_N PF18247.1 EGG20687.1 - 0.17 11.9 0.2 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Flax-rust effector AvrM N-terminal domain FapA PF03961.13 EGG20688.1 - 0.017 13.8 2.5 0.023 13.3 2.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A RNB PF00773.19 EGG20689.1 - 6.1e-21 75.1 1.2 1.7e-19 70.3 1.2 2.3 1 1 0 1 1 1 1 RNB domain RNB PF00773.19 EGG20690.1 - 1.9e-15 57.0 0.8 2.9e-15 56.4 0.1 1.6 2 0 0 2 2 2 1 RNB domain DUF4164 PF13747.6 EGG20690.1 - 0.14 12.4 0.0 1.8 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TLD PF07534.16 EGG20691.1 - 2.8e-40 137.7 1.9 1.1e-39 135.8 1.9 2.2 1 0 0 1 1 1 1 TLD Ank_2 PF12796.7 EGG20691.1 - 2.7e-38 130.4 12.3 1.2e-08 35.5 0.1 6.8 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG20691.1 - 1.1e-30 105.5 13.5 7.4e-07 29.6 0.0 10.3 7 2 5 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG20691.1 - 2.3e-25 88.3 12.0 0.00036 20.8 0.1 11.6 7 3 5 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG20691.1 - 2.8e-24 82.5 5.9 0.4 11.4 0.1 14.7 15 1 1 16 16 16 4 Ankyrin repeat LysM PF01476.20 EGG20691.1 - 3.1e-06 27.1 0.0 9.8e-06 25.5 0.0 2.0 1 0 0 1 1 1 1 LysM domain Ank PF00023.30 EGG20691.1 - 1.8e-05 25.0 9.0 21 5.8 0.1 8.9 7 2 1 8 8 8 1 Ankyrin repeat GRAM PF02893.20 EGG20691.1 - 0.011 15.6 0.1 0.14 12.1 0.0 2.5 2 0 0 2 2 2 0 GRAM domain tRNA-synt_His PF13393.6 EGG20692.1 - 7.5e-48 163.4 0.0 1.3e-47 162.6 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EGG20692.1 - 4.3e-15 55.6 2.2 9.3e-15 54.6 2.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EGG20692.1 - 1.6e-06 27.9 1.8 1.6e-06 27.9 1.8 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 EGG20692.1 - 6.5e-05 23.0 0.0 0.00046 20.2 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 EGG20692.1 - 0.00015 21.0 0.1 0.0013 17.9 0.1 2.3 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) UPF0239 PF06783.11 EGG20692.1 - 0.32 11.2 4.5 0.77 10.0 4.5 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) ExbD PF02472.16 EGG20692.1 - 0.96 9.6 6.9 3.4 7.8 0.2 3.0 2 1 1 3 3 3 0 Biopolymer transport protein ExbD/TolR MMS1_N PF10433.9 EGG20693.1 - 3.8e-37 128.1 19.1 4.3e-36 124.6 12.6 3.9 2 2 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGG20693.1 - 2.6e-18 66.4 0.2 7.7e-18 64.9 0.2 1.8 1 0 0 1 1 1 1 CPSF A subunit region Cofilin_ADF PF00241.20 EGG20696.1 - 1.7e-58 195.7 0.0 3.5e-20 72.0 0.0 3.1 3 0 0 3 3 3 3 Cofilin/tropomyosin-type actin-binding protein AAA_6 PF12774.7 EGG20698.1 - 5.3e-136 452.9 0.0 1.4e-134 448.2 0.0 3.5 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EGG20698.1 - 4.4e-119 398.7 18.6 4.4e-119 398.7 18.6 4.3 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EGG20698.1 - 7.1e-110 367.8 6.0 7.1e-110 367.8 6.0 6.5 7 1 0 7 7 6 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EGG20698.1 - 3.7e-73 245.3 0.0 3.7e-73 245.3 0.0 5.0 5 0 0 5 5 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 EGG20698.1 - 2.2e-71 240.2 0.0 2.9e-70 236.6 0.0 3.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGG20698.1 - 4.3e-48 164.1 4.6 1e-47 162.9 2.4 3.0 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EGG20698.1 - 4.7e-43 146.8 0.0 6.5e-36 123.5 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 EGG20698.1 - 5e-41 140.9 15.2 1e-40 139.8 15.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EGG20698.1 - 7.6e-39 133.1 0.0 3e-38 131.2 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGG20698.1 - 8.7e-34 116.5 0.0 2.4e-13 50.3 0.0 6.1 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EGG20698.1 - 1.5e-27 96.0 0.0 2.1e-26 92.3 0.0 3.2 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGG20698.1 - 3e-18 66.1 0.0 2e-17 63.5 0.0 2.6 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EGG20698.1 - 5.9e-13 49.3 0.6 0.0017 18.7 0.0 6.5 6 0 0 6 6 5 3 AAA domain AAA PF00004.29 EGG20698.1 - 5.8e-11 42.9 0.0 0.032 14.7 0.0 4.7 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGG20698.1 - 5e-09 36.4 0.1 0.18 12.0 0.0 5.2 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 EGG20698.1 - 6.2e-08 33.2 0.0 2.2 8.6 0.0 6.9 6 0 0 6 6 6 1 AAA ATPase domain AAA_lid_1 PF17857.1 EGG20698.1 - 2.2e-07 31.0 4.0 2.9e-06 27.4 0.0 3.6 3 0 0 3 3 3 1 AAA+ lid domain AAA_18 PF13238.6 EGG20698.1 - 3.2e-05 24.5 2.0 1.6 9.3 0.0 5.4 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 EGG20698.1 - 7.1e-05 22.6 0.0 2.3 7.9 0.0 4.0 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 EGG20698.1 - 0.00057 19.0 0.0 0.062 12.4 0.0 3.0 3 0 0 3 3 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 EGG20698.1 - 0.00072 19.9 0.1 0.12 12.7 0.0 3.7 4 0 0 4 4 3 1 AAA domain IstB_IS21 PF01695.17 EGG20698.1 - 0.0015 18.3 1.0 0.62 9.8 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_29 PF13555.6 EGG20698.1 - 0.0025 17.5 0.0 4.8 7.0 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EGG20698.1 - 0.0054 16.1 3.1 1.1 8.6 0.0 3.7 5 0 0 5 5 3 1 Magnesium chelatase, subunit ChlI PurL_C PF16904.5 EGG20698.1 - 0.035 14.4 0.0 0.22 11.9 0.0 2.4 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine synthase II C-terminus AAA_25 PF13481.6 EGG20698.1 - 0.045 13.3 0.0 0.29 10.7 0.0 2.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGG20698.1 - 0.053 13.2 0.1 18 5.0 0.0 4.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EGG20698.1 - 0.064 13.7 0.2 1.4e+02 2.9 0.0 4.6 5 0 0 5 5 3 0 RNA helicase ILEI PF15711.5 EGG20700.1 - 2.9e-70 232.8 10.7 6e-14 52.3 0.2 5.4 5 0 0 5 5 5 5 Interleukin-like EMT inducer Chal_sti_synt_C PF02797.15 EGG20700.1 - 0.1 12.6 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain Pkinase PF00069.25 EGG20701.1 - 1.5e-65 221.2 0.0 2e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20701.1 - 2.2e-32 112.4 0.0 5.8e-32 111.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG20701.1 - 0.0003 20.2 0.0 0.0083 15.5 0.0 2.2 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EGG20701.1 - 0.001 18.7 0.2 0.0022 17.6 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Inhibitor_I71 PF12628.7 EGG20701.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Ank_3 PF13606.6 EGG20702.1 - 0.0093 16.4 0.0 3.1 8.7 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EGG20702.1 - 0.031 14.9 0.0 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG20702.1 - 0.032 14.8 0.0 11 6.7 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) ELMO_CED12 PF04727.13 EGG20703.1 - 1.1e-28 100.5 0.4 3.4e-28 99.0 0.4 1.8 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 EGG20703.1 - 3.7e-07 30.2 1.2 3.7e-07 30.2 1.2 2.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3361) ubiquitin PF00240.23 EGG20704.1 - 1.2e-06 28.2 1.4 0.0024 17.6 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.8 EGG20704.1 - 0.0058 16.4 0.2 0.3 11.0 0.0 3.0 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Chorein_N PF12624.7 EGG20705.1 - 7.4e-23 80.9 8.1 1.2e-20 73.8 5.0 3.2 1 1 1 2 2 2 2 N-terminal region of Chorein or VPS13 HEAT PF02985.22 EGG20706.1 - 6.5e-07 29.1 2.2 1.3 9.5 0.0 6.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EGG20706.1 - 0.0062 16.9 0.0 0.99 9.8 0.0 3.9 4 0 0 4 4 4 1 HEAT repeats TAF6_C PF07571.13 EGG20706.1 - 0.021 15.1 6.2 10 6.5 0.0 5.7 6 1 1 7 7 7 0 TAF6 C-terminal HEAT repeat domain Cnd1 PF12717.7 EGG20706.1 - 0.15 12.1 0.0 0.15 12.1 0.0 6.7 6 1 1 7 7 7 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGG20706.1 - 0.4 10.2 18.4 0.2 11.2 0.1 4.8 5 0 0 5 5 5 0 CLASP N terminal AAA_18 PF13238.6 EGG20707.1 - 9.3e-10 39.2 0.1 2.2e-09 38.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EGG20707.1 - 3.8e-08 33.6 0.2 4.2e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Shikimate kinase APS_kinase PF01583.20 EGG20707.1 - 1.9e-06 27.8 0.9 0.023 14.6 0.2 2.3 1 1 1 2 2 2 2 Adenylylsulphate kinase dNK PF01712.19 EGG20707.1 - 0.00013 21.9 0.6 0.67 9.8 0.0 2.7 2 1 0 2 2 2 2 Deoxynucleoside kinase AAA_33 PF13671.6 EGG20707.1 - 0.00061 20.0 0.0 0.0015 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGG20707.1 - 0.0014 18.2 0.3 0.48 10.0 0.2 2.7 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.27 EGG20707.1 - 0.0028 18.2 0.2 0.0051 17.3 0.2 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGG20707.1 - 0.0033 17.8 0.1 0.0057 17.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Ploopntkinase1 PF18748.1 EGG20707.1 - 0.0092 15.5 0.0 2.9 7.4 0.0 2.2 2 0 0 2 2 2 2 P-loop Nucleotide Kinase1 DUF87 PF01935.17 EGG20707.1 - 0.012 15.7 0.5 0.025 14.7 0.5 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain DNA_pol3_delta2 PF13177.6 EGG20707.1 - 0.015 15.1 0.4 0.2 11.4 0.4 2.3 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_29 PF13555.6 EGG20707.1 - 0.016 14.9 0.4 0.032 14.0 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EGG20707.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGG20707.1 - 0.021 14.8 0.0 0.039 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGG20707.1 - 0.032 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.10 EGG20707.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.6 EGG20707.1 - 0.059 13.6 0.0 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EGG20707.1 - 0.077 12.7 2.6 0.64 9.7 0.2 2.4 2 1 0 2 2 2 0 Cytidylate kinase RsgA_GTPase PF03193.16 EGG20707.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase Peptidase_C15 PF01470.17 EGG20707.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Pyroglutamyl peptidase Zeta_toxin PF06414.12 EGG20707.1 - 0.14 11.5 0.2 0.42 9.9 0.2 1.8 2 0 0 2 2 2 0 Zeta toxin COPI_assoc PF08507.10 EGG20708.1 - 6.2e-15 55.4 9.6 7.7e-15 55.1 9.6 1.1 1 0 0 1 1 1 1 COPI associated protein DUF4345 PF14248.6 EGG20708.1 - 0.84 9.6 13.3 0.16 11.9 9.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) LapA_dom PF06305.11 EGG20708.1 - 0.92 9.4 7.5 1.4 8.8 0.1 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Dicty_CAR PF05462.11 EGG20709.1 - 1.7e-13 50.4 16.8 2.3e-13 50.0 16.8 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 EGG20709.1 - 3.1e-10 39.7 18.7 6.8e-10 38.6 18.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 EGG20709.1 - 3.7e-05 22.9 19.6 0.017 14.2 13.4 2.3 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region 7tm_1 PF00001.21 EGG20709.1 - 0.091 12.1 19.7 0.25 10.6 19.7 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SSP160 PF06933.11 EGG20709.1 - 1.7 6.8 11.7 2.3 6.3 11.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TMEM154 PF15102.6 EGG20709.1 - 9.5 6.1 8.7 27 4.6 0.2 2.3 2 0 0 2 2 2 0 TMEM154 protein family DUF1084 PF06454.11 EGG20710.1 - 2.4e-60 204.2 17.9 3.3e-60 203.8 17.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF2339 PF10101.9 EGG20710.1 - 0.022 13.4 0.7 0.031 12.9 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Holin_SPP1 PF04688.13 EGG20710.1 - 0.072 13.3 0.1 0.072 13.3 0.1 3.2 3 0 0 3 3 3 0 SPP1 phage holin adh_short PF00106.25 EGG20711.1 - 8.8e-18 64.5 0.0 1.8e-10 40.6 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG20711.1 - 2.9e-12 46.7 0.0 3.1e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase EGF_2 PF07974.13 EGG20712.1 - 0.00013 22.3 35.7 0.02 15.3 16.4 2.8 2 0 0 2 2 2 2 EGF-like domain DUF3844 PF12955.7 EGG20712.1 - 0.42 10.8 15.4 1.9 8.7 2.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3844) EGF_2 PF07974.13 EGG20713.1 - 3.4e-07 30.5 33.2 8e-05 22.9 13.8 2.7 2 0 0 2 2 2 2 EGF-like domain DUF2967 PF11179.8 EGG20713.1 - 0.0041 15.3 0.1 0.0074 14.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2967) hEGF PF12661.7 EGG20713.1 - 0.0087 16.7 24.5 0.056 14.1 9.4 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF Pollen_Ole_e_I PF01190.17 EGG20713.1 - 0.019 15.3 0.4 0.16 12.4 0.0 2.7 3 0 0 3 3 3 0 Pollen proteins Ole e I like TIG PF01833.24 EGG20713.1 - 0.034 14.2 16.3 0.14 12.3 0.1 4.6 5 0 0 5 5 5 0 IPT/TIG domain DUF3844 PF12955.7 EGG20713.1 - 0.46 10.6 17.6 4.3 7.5 2.2 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3844) Patatin PF01734.22 EGG20714.1 - 2.8e-14 53.8 0.0 3.2e-13 50.3 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase DUF16 PF01519.16 EGG20714.1 - 8.1 7.0 13.7 0.11 13.0 5.1 2.3 3 0 0 3 3 3 0 Protein of unknown function DUF16 DUF3244 PF11589.8 EGG20715.1 - 2.5 8.2 12.2 5.3 7.2 1.3 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3244) Pox_LP_H2 PF03356.15 EGG20717.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral late protein H2 Acetyltransf_1 PF00583.25 EGG20718.1 - 1.5e-12 47.8 0.0 1.9e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG20718.1 - 1.5e-08 34.9 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG20718.1 - 3.2e-08 33.6 0.0 3.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG20718.1 - 8.3e-08 32.1 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGG20718.1 - 0.00039 20.5 0.1 0.001 19.2 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain SPOR PF05036.13 EGG20718.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 2 0 0 2 2 2 0 Sporulation related domain Acetyltransf_4 PF13420.7 EGG20718.1 - 0.026 14.6 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nop10p PF04135.12 EGG20719.1 - 0.083 12.9 1.2 0.085 12.9 1.2 1.2 1 1 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family MIT_C PF16565.5 EGG20720.1 - 4.6e-50 169.3 1.5 7.1e-50 168.7 1.5 1.3 1 0 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT MIT PF04212.18 EGG20720.1 - 3.7e-18 65.4 0.4 5.6e-18 64.8 0.4 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Use1 PF09753.9 EGG20720.1 - 0.03 14.0 0.1 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 NAD_binding_10 PF13460.6 EGG20721.1 - 6.7e-10 39.2 0.0 8e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGG20721.1 - 1.4e-05 24.4 0.1 0.00014 21.2 0.0 2.3 1 1 1 3 3 3 1 Male sterility protein Semialdhyde_dh PF01118.24 EGG20721.1 - 9.1e-05 22.9 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain HIM1 PF08732.10 EGG20721.1 - 0.022 14.3 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 HIM1 Epimerase PF01370.21 EGG20721.1 - 0.085 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG20721.1 - 0.12 11.3 0.2 0.24 10.4 0.2 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EGG20721.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.5 2 0 0 2 2 2 0 KR domain zinc_ribbon_12 PF11331.8 EGG20722.1 - 0.036 13.9 0.1 0.069 13.0 0.1 1.5 1 0 0 1 1 1 0 Probable zinc-ribbon domain RB_B PF01857.20 EGG20722.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Mito_carr PF00153.27 EGG20723.1 - 1.2e-48 163.0 7.1 3.8e-19 68.4 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 EGG20723.1 - 0.01 15.9 0.5 0.03 14.4 0.5 1.8 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Dickkopf_N PF04706.12 EGG20724.1 - 0.0082 16.6 10.3 0.0082 16.6 10.3 17.2 15 5 3 18 18 18 7 Dickkopf N-terminal cysteine-rich region EB PF01683.18 EGG20724.1 - 0.013 15.7 9.2 0.013 15.7 9.2 21.1 7 5 13 20 20 20 0 EB module Adeno_E4 PF05385.11 EGG20724.1 - 2.3 8.4 5.4 25 5.0 0.1 3.5 4 0 0 4 4 4 0 Mastadenovirus early E4 13 kDa protein ketoacyl-synt PF00109.26 EGG20725.1 - 5.3 6.5 5.1 8.2 5.9 0.1 2.4 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain EB PF01683.18 EGG20726.1 - 0.0096 16.2 9.5 0.0096 16.2 9.5 17.8 7 5 8 15 15 15 7 EB module Aminotran_4 PF01063.19 EGG20728.1 - 1.3e-33 116.8 0.0 1.6e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV zf-Tim10_DDP PF02953.15 EGG20729.1 - 1.7e-10 40.4 2.5 1.7e-10 40.4 2.5 1.5 2 0 0 2 2 2 1 Tim10/DDP family zinc finger DUF2116 PF09889.9 EGG20729.1 - 0.013 15.5 3.6 0.041 13.9 0.3 2.3 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ank_4 PF13637.6 EGG20731.1 - 3.4e-16 59.4 5.7 1e-08 35.5 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGG20731.1 - 2.4e-15 56.2 0.9 2.1e-05 24.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EGG20731.1 - 3.3e-15 56.4 0.7 1.9e-10 41.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG20731.1 - 5.1e-12 45.8 0.3 9.1e-08 32.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG20731.1 - 2.8e-08 33.4 0.4 0.014 15.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat DUF2129 PF09902.9 EGG20731.1 - 0.16 12.1 1.4 0.26 11.4 0.6 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) MFS_1 PF07690.16 EGG20733.1 - 5.6e-30 104.5 6.1 5.6e-30 104.5 6.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG20733.1 - 6.8e-09 35.1 15.1 1.2e-08 34.2 15.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter WD40 PF00400.32 EGG20734.1 - 1.5e-49 164.9 12.8 2.6e-09 37.5 0.0 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EGG20734.1 - 1.7e-42 144.7 2.6 5.6e-42 143.1 3.0 1.7 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EGG20734.1 - 2.8e-14 53.2 0.0 0.0051 17.1 0.0 4.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EGG20734.1 - 1.2e-05 25.1 0.1 3.3e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 EGG20734.1 - 2.6e-05 23.4 0.1 0.2 10.6 0.0 3.8 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH_2 PF16045.5 EGG20734.1 - 0.00011 21.1 0.1 0.0022 17.0 0.0 2.4 2 0 0 2 2 2 1 LisH Frtz PF11768.8 EGG20734.1 - 0.0014 17.1 0.0 0.002 16.5 0.0 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 EGG20734.1 - 0.0031 16.1 0.0 0.0052 15.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain WD40_like PF17005.5 EGG20734.1 - 0.0035 16.7 0.0 0.21 10.9 0.0 3.1 3 1 0 3 3 3 1 WD40-like domain Mucin PF01456.17 EGG20734.1 - 0.0087 16.1 6.4 0.0087 16.1 6.4 5.3 3 1 1 4 4 4 1 Mucin-like glycoprotein AKAP7_NLS PF10469.9 EGG20735.1 - 5.6e-34 117.8 0.0 7.2e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 EGG20735.1 - 0.00031 20.7 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 EGG20735.1 - 0.0044 17.2 0.0 2.8 8.2 0.0 2.4 2 1 0 2 2 2 2 LigT like Phosphoesterase Abhydrolase_6 PF12697.7 EGG20736.1 - 0.00012 22.8 0.0 0.0002 22.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG20736.1 - 0.0024 17.6 0.1 0.0044 16.7 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGG20736.1 - 0.064 13.0 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase N_BRCA1_IG PF16158.5 EGG20737.1 - 6.5e-30 103.9 0.0 1.4e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 EGG20737.1 - 1.6e-15 56.8 0.0 2.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 PB1 domain ZZ PF00569.17 EGG20737.1 - 1.7e-09 37.3 3.7 3.1e-09 36.5 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 EGG20737.1 - 0.24 11.7 4.7 0.45 10.9 4.7 1.4 1 0 0 1 1 1 0 C1 domain Ala_racemase_N PF01168.20 EGG20739.1 - 4e-18 65.9 0.0 5.2e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.20 EGG20742.1 - 1.7e-115 386.6 8.0 1.7e-115 386.6 8.0 1.7 2 0 0 2 2 2 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EGG20742.1 - 4.1e-28 97.8 0.0 4.1e-28 97.8 0.0 2.7 3 0 0 3 3 3 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EGG20742.1 - 2.9e-15 56.6 0.1 2.9e-15 56.6 0.1 3.6 4 0 0 4 4 4 1 Adaptin C-terminal domain Cnd1 PF12717.7 EGG20742.1 - 5.4e-05 23.3 13.8 0.00015 21.9 0.0 3.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGG20742.1 - 0.0027 18.0 0.4 0.19 12.1 0.0 3.3 3 0 0 3 3 3 1 HEAT repeats TFIIA PF03153.13 EGG20742.1 - 0.67 9.9 25.9 1.2 9.1 25.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 EGG20742.1 - 1.1 8.2 33.7 2 7.3 33.7 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EIF4E-T PF10477.9 EGG20742.1 - 1.9 7.2 16.0 2.9 6.6 16.0 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Gcn1_N PF12074.8 EGG20743.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal VWA_2 PF13519.6 EGG20744.1 - 0.082 13.6 0.1 1.2 9.8 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain BLM10_N PF16547.5 EGG20745.1 - 0.12 12.6 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal PKcGMP_CC PF16808.5 EGG20745.1 - 0.86 9.5 5.1 1.3 9.0 0.2 2.2 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pkinase PF00069.25 EGG20746.1 - 9.6e-36 123.5 3.2 9.6e-36 123.5 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20746.1 - 1.6e-20 73.5 1.0 3e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 EGG20746.1 - 2e-16 60.3 0.2 2e-16 60.3 0.2 2.6 2 0 0 2 2 2 1 Ribonuclease 2-5A DUF4551 PF15087.6 EGG20746.1 - 0.0092 14.9 13.8 0.014 14.3 13.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4551) RIO1 PF01163.22 EGG20746.1 - 0.0097 15.5 0.2 0.0097 15.5 0.2 2.6 2 1 0 2 2 1 1 RIO1 family Kdo PF06293.14 EGG20746.1 - 0.017 14.5 0.1 0.053 12.9 0.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PEX11 PF05648.14 EGG20746.1 - 0.16 11.4 3.4 0.47 9.9 3.4 1.9 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) BSP_II PF05432.11 EGG20746.1 - 0.16 11.6 25.2 0.27 10.9 25.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) APH PF01636.23 EGG20746.1 - 0.18 11.7 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family G6B PF15096.6 EGG20746.1 - 0.21 11.3 0.3 0.49 10.2 0.3 1.5 1 0 0 1 1 1 0 G6B family U79_P34 PF03064.16 EGG20746.1 - 3 7.1 16.6 9.4 5.5 16.6 1.8 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Peptidase_C1 PF00112.23 EGG20747.1 - 1.3e-62 211.8 5.2 1.8e-62 211.3 4.2 1.6 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG20747.1 - 4.3e-11 43.1 4.1 9.2e-11 42.0 4.1 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGG20747.1 - 0.0017 17.2 2.2 0.13 11.0 0.1 2.3 2 1 0 2 2 2 2 Peptidase C1-like family DUF3446 PF11928.8 EGG20747.1 - 1.6 9.1 32.4 1.6 9.1 17.5 3.0 3 0 0 3 3 3 0 Early growth response N-terminal domain SapB_2 PF03489.17 EGG20750.1 - 1.5e-09 37.8 1.5 3.9e-09 36.5 1.5 1.8 1 0 0 1 1 1 1 Saposin-like type B, region 2 DUF908 PF06012.12 EGG20750.1 - 0.002 17.6 1.5 0.0022 17.5 1.5 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) SapB_1 PF05184.15 EGG20750.1 - 0.14 12.2 10.3 0.05 13.6 5.1 2.5 2 1 0 2 2 2 0 Saposin-like type B, region 1 Mucin PF01456.17 EGG20750.1 - 1.5 8.8 38.1 3.4 7.7 38.1 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 EGG20750.1 - 8.2 4.4 14.7 9.5 4.2 14.7 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Hist_deacetyl PF00850.19 EGG20751.1 - 5.4e-82 275.7 0.1 5.4e-82 275.7 0.1 1.5 2 0 0 2 2 2 1 Histone deacetylase domain DUF5613 PF18467.1 EGG20751.1 - 0.052 14.0 0.7 0.13 12.7 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5613) DUF4834 PF16118.5 EGG20752.1 - 0.11 13.5 1.5 0.25 12.3 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) O-antigen_lig PF13425.6 EGG20752.1 - 0.78 8.5 6.0 1.1 7.9 6.0 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF2615 PF11027.8 EGG20752.1 - 7.6 6.7 7.8 1.5 9.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Myb_DNA-binding PF00249.31 EGG20753.1 - 1.4e-06 28.4 0.1 8.1e-05 22.7 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain CHDCT2 PF08074.11 EGG20753.1 - 0.03 14.5 0.0 0.097 12.8 0.0 1.8 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Dicty_REP PF05086.12 EGG20753.1 - 3.8 5.4 7.3 6.6 4.6 7.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CBS PF00571.28 EGG20754.1 - 2.8e-30 104.5 5.1 5.9e-11 42.6 0.7 4.9 4 0 0 4 4 4 4 CBS domain Cyclin_N PF00134.23 EGG20754.1 - 1.1e-16 60.7 0.7 3.3e-15 56.0 1.1 2.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGG20754.1 - 0.018 15.1 0.1 3.3 7.8 0.0 2.8 2 1 0 2 2 2 0 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 EGG20754.1 - 0.066 13.6 0.0 0.32 11.4 0.0 2.3 1 1 0 1 1 1 0 Cyclin C-terminal domain PALP PF00291.25 EGG20756.1 - 2e-50 171.9 0.1 3.2e-50 171.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C3HC4_3 PF13920.6 EGG20756.1 - 1.3e-12 47.4 13.2 2.1e-12 46.7 13.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG20756.1 - 4.7e-08 32.8 13.5 8.4e-08 32.0 13.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGG20756.1 - 0.0012 18.8 11.7 0.0024 17.8 11.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF812 PF05667.11 EGG20756.1 - 0.63 8.8 51.7 0.78 8.5 36.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Peptidase_S64 PF08192.11 EGG20756.1 - 6.1 5.2 37.0 9.9 4.5 37.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 zf-RING_UBOX PF13445.6 EGG20756.1 - 6.4 6.9 12.1 1.3e+02 2.7 13.1 2.5 1 1 1 2 2 2 0 RING-type zinc-finger 6PF2K PF01591.18 EGG20757.1 - 3.9e-68 229.1 0.2 5.7e-68 228.5 0.2 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGG20757.1 - 8.6e-32 110.4 0.1 2.1e-31 109.2 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGG20757.1 - 0.00013 22.1 0.0 0.0003 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AIP3 PF03915.13 EGG20757.1 - 0.00034 19.8 0.1 0.00062 19.0 0.1 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 KTI12 PF08433.10 EGG20757.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EGG20757.1 - 0.088 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 EGG20757.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Mg_chelatase PF01078.21 EGG20757.1 - 0.15 11.4 0.1 0.65 9.4 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 EGG20757.1 - 0.18 12.2 0.0 0.57 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.7 EGG20759.1 - 1.3e-07 32.4 0.0 1.6e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG20759.1 - 7.3e-05 22.5 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Aminotran_1_2 PF00155.21 EGG20760.1 - 9.5e-42 143.4 0.0 1.1e-41 143.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGG20760.1 - 0.0011 17.6 0.0 0.0017 17.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Guanylate_kin PF00625.21 EGG20760.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase LIM PF00412.22 EGG20761.1 - 4.5e-58 193.3 38.3 5e-15 55.5 3.5 4.2 4 0 0 4 4 4 4 LIM domain ACR_tran PF00873.19 EGG20761.1 - 0.17 9.5 2.2 0.23 9.0 2.2 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family zf-C2H2_6 PF13912.6 EGG20761.1 - 3.8 7.6 16.2 0.22 11.6 2.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger BRCT_2 PF16589.5 EGG20762.1 - 1.5e-12 47.8 0.0 3.4e-08 33.8 0.0 3.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG20762.1 - 2.1e-06 28.0 0.3 0.003 17.9 0.0 3.9 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain AT_hook PF02178.19 EGG20762.1 - 0.0053 16.5 0.4 0.058 13.3 0.4 3.0 1 0 0 1 1 1 1 AT hook motif ATP-synt_C PF00137.21 EGG20763.1 - 1.3e-31 108.7 27.7 3.6e-16 59.2 7.4 2.3 2 0 0 2 2 2 2 ATP synthase subunit C ATP-synt_C PF00137.21 EGG20764.1 - 1.1e-27 96.2 35.8 6.4e-18 64.9 16.3 2.4 2 0 0 2 2 2 2 ATP synthase subunit C MutS_V PF00488.21 EGG20765.1 - 2.9e-71 239.4 0.0 5.6e-71 238.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 EGG20765.1 - 3e-30 104.7 0.2 8.1e-30 103.4 0.2 1.8 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 EGG20765.1 - 3.1e-28 99.3 1.0 3.1e-28 99.3 1.0 2.6 3 1 0 3 3 3 1 MutS domain III MutS_II PF05188.17 EGG20765.1 - 1.6e-11 44.6 2.0 2.3e-11 44.2 0.8 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EGG20765.1 - 1.4e-05 25.3 0.6 4.4e-05 23.8 0.6 1.9 1 0 0 1 1 1 1 MutS family domain IV 6PF2K PF01591.18 EGG20765.1 - 0.0024 17.2 0.3 0.11 11.8 0.0 2.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Pro_isomerase PF00160.21 EGG20766.1 - 9.9e-52 175.4 0.2 3.4e-51 173.7 0.4 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SQS_PSY PF00494.19 EGG20766.1 - 5.4e-41 140.8 0.0 7.9e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase TPR_1 PF00515.28 EGG20766.1 - 1.6e-12 46.7 10.5 3.5e-06 26.6 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG20766.1 - 3.2e-11 42.4 6.4 0.004 17.2 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGG20766.1 - 6.7e-08 32.7 2.0 2.7e-06 27.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG20766.1 - 1.8e-07 30.8 5.2 0.012 15.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG20766.1 - 1.1e-06 28.2 11.8 0.0049 16.5 2.6 4.0 3 1 1 4 4 4 3 TPR repeat TPR_9 PF13371.6 EGG20766.1 - 0.00017 21.6 0.8 0.00044 20.3 0.3 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG20766.1 - 0.00073 20.0 9.6 0.005 17.3 1.3 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG20766.1 - 0.00082 20.0 1.0 0.21 12.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG20766.1 - 0.00098 19.0 1.4 4.3 7.6 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG20766.1 - 0.0024 18.5 0.4 0.3 12.0 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG20766.1 - 0.0048 17.4 1.4 16 6.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.9 EGG20766.1 - 0.027 14.2 1.9 0.05 13.3 1.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC3 PF12895.7 EGG20766.1 - 0.039 14.2 2.8 3.7 7.8 0.9 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGG20766.1 - 0.06 13.7 3.2 0.19 12.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG20766.1 - 0.092 12.8 1.1 3 8.0 0.1 3.1 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 EGG20766.1 - 0.27 11.6 4.5 0.17 12.2 1.7 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4564 PF15169.6 EGG20767.1 - 0.053 13.2 0.6 0.7 9.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4564) 4HBT PF03061.22 EGG20768.1 - 3.9e-10 40.0 0.2 8.9e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily Pico_P2B PF01552.17 EGG20768.1 - 0.28 11.3 3.3 1.2 9.4 3.1 2.2 1 1 1 2 2 2 0 Picornavirus 2B protein UbiA PF01040.18 EGG20769.1 - 5.3e-19 68.5 5.7 6e-19 68.3 5.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Mem_trans PF03547.18 EGG20769.1 - 0.023 13.1 1.4 0.041 12.3 1.4 1.4 1 0 0 1 1 1 0 Membrane transport protein Vac14_Fab1_bd PF12755.7 EGG20770.1 - 1.1e-05 25.9 1.9 0.0017 18.9 0.1 4.0 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGG20770.1 - 0.00019 21.4 3.5 0.31 11.4 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 EGG20770.1 - 0.00023 21.5 0.0 1 9.8 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats SR-25 PF10500.9 EGG20770.1 - 0.0012 18.5 12.6 0.011 15.4 13.6 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Cnd1 PF12717.7 EGG20770.1 - 0.0032 17.5 0.5 0.0032 17.5 0.5 4.2 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 SMK-1 PF04802.15 EGG20770.1 - 0.006 16.4 0.2 0.045 13.6 0.0 2.6 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 HEAT_EZ PF13513.6 EGG20770.1 - 0.029 14.9 0.1 25 5.5 0.2 4.1 4 0 0 4 4 4 0 HEAT-like repeat Phage_C PF12025.8 EGG20770.1 - 0.055 13.3 0.1 0.28 11.1 0.2 2.2 2 0 0 2 2 2 0 Phage protein C DUF4629 PF15442.6 EGG20770.1 - 0.059 13.6 5.0 0.15 12.2 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) IMUP PF15761.5 EGG20770.1 - 0.96 10.2 8.2 1.9 9.2 8.2 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF5470 PF17564.2 EGG20770.1 - 2.7 8.3 8.0 11 6.2 5.6 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5470) SPC22 PF04573.12 EGG20771.1 - 2.7e-35 121.4 3.2 2.9e-35 121.3 3.2 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Response_reg PF00072.24 EGG20772.1 - 6.2e-30 103.6 0.5 7.3e-23 80.9 0.0 3.3 3 0 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.26 EGG20772.1 - 1.1e-28 100.0 0.2 2.6e-28 98.7 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG20772.1 - 5.4e-07 29.5 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGG20772.1 - 0.00024 20.9 0.0 0.00088 19.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1664 PF07889.12 EGG20772.1 - 0.012 15.7 0.8 0.03 14.4 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HATPase_c_2 PF13581.6 EGG20772.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain zf-RING_6 PF14835.6 EGG20773.1 - 7.6e-09 35.3 5.2 1.8e-08 34.1 5.2 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 EGG20773.1 - 4.3e-08 32.9 17.0 4.3e-08 32.9 17.0 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG20773.1 - 1.8e-06 27.8 10.9 1.8e-06 27.8 10.9 2.8 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGG20773.1 - 4.2e-06 26.5 16.4 8.4e-06 25.6 12.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG20773.1 - 2.4e-05 24.1 16.9 2.4e-05 24.1 16.9 3.5 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG20773.1 - 2.9e-05 24.3 15.6 2.9e-05 24.3 15.6 3.1 3 0 0 3 3 3 1 Ring finger domain SAP PF02037.27 EGG20773.1 - 9.2e-05 22.1 0.4 0.00017 21.3 0.4 1.5 1 0 0 1 1 1 1 SAP domain zf-RING_5 PF14634.6 EGG20773.1 - 0.00018 21.4 19.4 0.00023 21.1 15.5 2.7 2 0 0 2 2 2 1 zinc-RING finger domain DUF4484 PF14831.6 EGG20773.1 - 0.041 13.9 11.8 0.082 12.9 11.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Mucin PF01456.17 EGG20773.1 - 0.079 13.0 11.9 0.16 12.0 11.9 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein MCM2_N PF12619.8 EGG20773.1 - 0.47 10.7 9.4 0.17 12.2 2.2 2.4 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 zf-ANAPC11 PF12861.7 EGG20773.1 - 1.5 8.9 12.2 0.27 11.3 7.8 2.0 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGG20773.1 - 1.6 9.0 24.9 0.06 13.5 16.8 2.8 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGG20773.1 - 3.2 8.1 17.2 0.22 11.9 10.6 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain AAA PF00004.29 EGG20774.1 - 1.8e-38 132.0 0.0 1.2e-26 93.7 0.0 3.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EGG20774.1 - 7.7e-28 96.7 3.9 2.1e-27 95.3 3.9 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal UFD1 PF03152.14 EGG20774.1 - 9.6e-08 31.7 0.2 1.3e-06 28.0 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin fusion degradation protein UFD1 AAA_lid_3 PF17862.1 EGG20774.1 - 2.2e-07 30.6 0.3 4.4e-06 26.4 0.1 2.4 2 0 0 2 2 2 1 AAA+ lid domain PEX-2N PF09263.10 EGG20774.1 - 3.2e-06 27.4 0.1 1.3e-05 25.4 0.1 2.2 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 EGG20774.1 - 1e-05 26.0 0.1 0.014 15.8 0.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EGG20774.1 - 0.0021 17.8 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGG20774.1 - 0.0079 15.6 0.0 0.031 13.7 0.0 2.0 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Molydop_binding PF01568.21 EGG20774.1 - 0.013 15.5 0.9 0.059 13.4 0.0 2.4 3 0 0 3 3 2 0 Molydopterin dinucleotide binding domain NACHT PF05729.12 EGG20774.1 - 0.03 14.2 0.3 0.86 9.5 0.4 2.8 2 1 0 2 2 1 0 NACHT domain Sigma54_activat PF00158.26 EGG20774.1 - 0.033 13.9 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 EGG20774.1 - 0.043 13.6 0.2 0.099 12.4 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CDC48_N PF02359.18 EGG20774.1 - 0.049 13.8 0.5 0.53 10.5 0.0 3.0 4 0 0 4 4 3 0 Cell division protein 48 (CDC48), N-terminal domain AAA_33 PF13671.6 EGG20774.1 - 0.05 13.8 0.6 2.9 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Rho_RNA_bind PF07497.12 EGG20774.1 - 0.084 12.8 0.0 0.39 10.6 0.0 2.1 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain AAA_22 PF13401.6 EGG20774.1 - 0.086 13.1 0.1 2.5 8.4 0.1 3.3 2 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EGG20774.1 - 0.39 11.3 4.7 0.94 10.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGG20774.1 - 0.58 10.7 0.0 0.58 10.7 0.0 4.1 4 1 0 4 4 3 0 ABC transporter PAS_2 PF08446.11 EGG20774.1 - 3.2 8.5 8.0 4 8.1 0.2 3.7 4 0 0 4 4 3 0 PAS fold DUF4470 PF14737.6 EGG20776.1 - 2.9e-08 33.8 0.0 1.3e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) TPR_12 PF13424.6 EGG20776.1 - 1.8e-07 31.3 0.0 0.00046 20.4 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG20776.1 - 1.9e-07 30.7 0.2 0.00022 20.9 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.6 EGG20776.1 - 1.5e-06 28.6 0.0 7.5e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG20776.1 - 4.5e-06 26.4 0.3 0.12 12.6 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG20776.1 - 5.5e-06 26.2 3.7 0.058 13.6 0.9 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG20776.1 - 1.8e-05 24.4 0.0 0.36 11.0 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG20776.1 - 1.8e-05 24.3 2.4 0.083 12.7 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG20776.1 - 0.00014 22.0 1.1 0.00032 20.8 0.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EGG20776.1 - 0.051 13.6 0.5 0.87 9.7 0.4 2.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 EGG20776.1 - 0.16 12.1 0.4 12 6.0 0.4 2.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) Bact_lectin PF18483.1 EGG20777.1 - 1.4e-22 80.7 2.6 1.8e-22 80.3 2.6 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EGG20777.1 - 3e-20 72.8 0.1 4.1e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 Legume lectin domain Lectin_leg-like PF03388.13 EGG20777.1 - 5.2e-08 32.5 1.4 3.6e-07 29.8 1.4 2.0 1 1 0 1 1 1 1 Legume-like lectin family Androgen_recep PF02166.16 EGG20778.1 - 0.096 11.5 1.1 0.13 11.1 1.1 1.1 1 0 0 1 1 1 0 Androgen receptor NTP_transf_2 PF01909.23 EGG20779.1 - 9.8e-09 35.4 1.5 1.7e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EGG20779.1 - 1.9e-07 31.2 0.0 1.9e-07 31.2 0.0 4.5 4 0 0 4 4 4 1 Cid1 family poly A polymerase Polbeta PF18765.1 EGG20779.1 - 0.011 15.8 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DNA_pol_A_exo1 PF01612.20 EGG20780.1 - 5.4e-17 62.1 0.0 1.9e-16 60.3 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease Ank_2 PF12796.7 EGG20781.1 - 0.0032 18.0 0.1 13 6.4 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG20781.1 - 0.022 15.3 0.0 65 4.3 0.0 4.5 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Thioredoxin PF00085.20 EGG20782.1 - 8.8e-26 89.9 0.0 2.6e-25 88.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin UBX PF00789.20 EGG20782.1 - 1.8e-17 63.3 0.0 4.1e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain ZZ PF00569.17 EGG20782.1 - 2.1e-10 40.2 9.7 4.4e-10 39.2 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Thioredoxin_8 PF13905.6 EGG20782.1 - 1.8e-06 28.2 1.2 1.6e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like UBA PF00627.31 EGG20782.1 - 1.5e-05 24.8 0.0 3.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain AhpC-TSA PF00578.21 EGG20782.1 - 0.00013 21.9 0.0 0.00041 20.3 0.0 1.8 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 EGG20782.1 - 0.00054 20.4 2.6 0.0026 18.2 0.1 3.0 2 1 0 2 2 2 1 Thioredoxin-like domain C1_2 PF03107.16 EGG20782.1 - 0.0013 19.0 5.6 0.0029 17.9 5.6 1.5 1 0 0 1 1 1 1 C1 domain Redoxin PF08534.10 EGG20782.1 - 0.0028 17.4 0.5 0.0066 16.2 0.0 1.8 2 0 0 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 EGG20782.1 - 0.0034 17.5 0.0 0.0098 16.1 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Macoilin PF09726.9 EGG20782.1 - 0.0063 15.1 12.4 0.0077 14.9 12.4 1.1 1 0 0 1 1 1 1 Macoilin family OST3_OST6 PF04756.13 EGG20782.1 - 0.015 14.7 0.1 0.031 13.6 0.1 1.5 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Reo_P9 PF06043.11 EGG20782.1 - 0.036 13.5 0.7 0.068 12.6 0.7 1.3 1 0 0 1 1 1 0 Reovirus P9-like family Asp-B-Hydro_N PF05279.11 EGG20782.1 - 3 7.9 17.1 5.9 6.9 17.1 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LRR_8 PF13855.6 EGG20783.1 - 0.034 13.9 0.7 2.2 8.1 0.3 3.6 2 0 0 2 2 2 0 Leucine rich repeat EGF_2 PF07974.13 EGG20783.1 - 0.082 13.3 7.3 0.19 12.1 7.3 1.6 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.24 EGG20783.1 - 3.7 7.7 20.1 0.095 12.8 0.6 4.6 4 1 0 4 4 4 0 IPT/TIG domain Tweety PF04906.13 EGG20784.1 - 4.6e-05 22.3 0.6 0.00031 19.6 0.1 2.3 2 0 0 2 2 2 1 Tweety Oxidored_q2 PF00420.24 EGG20784.1 - 0.41 10.3 6.5 1.2 8.8 1.5 3.2 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 4HB_MCP_1 PF12729.7 EGG20784.1 - 1 8.9 3.8 2.9 7.4 0.1 2.9 2 1 1 3 3 3 0 Four helix bundle sensory module for signal transduction TLD PF07534.16 EGG20785.1 - 1.5e-32 112.8 4.8 1.5e-32 112.8 4.8 4.4 5 0 0 5 5 5 1 TLD WD40 PF00400.32 EGG20785.1 - 1.1e-11 45.1 12.7 0.00099 19.9 1.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat LysM PF01476.20 EGG20785.1 - 1.9e-05 24.7 0.0 6.1e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 LysM domain ANAPC4_WD40 PF12894.7 EGG20785.1 - 5.6e-05 23.4 0.3 0.0031 17.8 0.2 3.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RWD PF05773.22 EGG20785.1 - 0.0031 17.8 0.2 0.0094 16.2 0.2 1.8 1 0 0 1 1 1 1 RWD domain DUF1951 PF09188.10 EGG20785.1 - 0.0097 15.9 0.9 0.0097 15.9 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1951) ADK PF00406.22 EGG20786.1 - 1.5e-10 41.3 1.6 1.3e-09 38.3 1.4 2.3 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGG20786.1 - 8.6e-10 39.2 0.0 3e-09 37.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG20786.1 - 0.0033 18.0 0.0 0.0084 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIG PF01833.24 EGG20787.1 - 5.6e-33 112.9 81.2 1.2e-06 28.5 2.8 11.6 10 2 1 11 11 11 9 IPT/TIG domain EGF_2 PF07974.13 EGG20787.1 - 0.0016 18.7 15.6 0.0042 17.4 15.6 1.8 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 EGG20787.1 - 0.26 11.6 11.4 0.73 10.2 11.4 1.8 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGG20787.1 - 0.36 11.5 7.7 1.5 9.6 7.7 2.2 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_CA PF07645.15 EGG20787.1 - 1.8 8.8 10.6 4.9 7.4 10.6 1.7 1 0 0 1 1 1 0 Calcium-binding EGF domain EGF_Tenascin PF18720.1 EGG20787.1 - 7.3 6.8 9.0 19 5.4 9.0 1.8 1 0 0 1 1 1 0 Tenascin EGF domain PDCD2_C PF04194.13 EGG20788.1 - 2.6e-32 112.3 4.0 6.6e-32 111.0 4.0 1.7 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 EGG20788.1 - 7.7e-10 38.7 16.3 1.2e-07 31.7 13.6 3.5 2 1 0 2 2 2 2 MYND finger FNIP PF05725.12 EGG20790.1 - 2.6e-12 46.7 28.2 9e-05 22.6 0.1 9.1 6 3 2 8 8 8 5 FNIP Repeat F-box-like PF12937.7 EGG20790.1 - 0.0077 16.1 0.6 0.027 14.4 0.1 2.3 2 0 0 2 2 2 1 F-box-like DDE_Tnp_4 PF13359.6 EGG20791.1 - 4.9e-24 84.8 0.0 1e-23 83.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 EGG20791.1 - 2.5e-09 36.7 0.2 5e-09 35.7 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGG20791.1 - 0.00037 20.2 0.2 0.0018 18.0 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain RR_TM4-6 PF06459.12 EGG20791.1 - 0.11 12.3 8.1 0.24 11.2 8.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 EGG20791.1 - 0.13 11.2 3.5 0.55 9.2 3.4 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EGG20791.1 - 0.16 10.7 4.2 0.25 10.1 4.2 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EGG20791.1 - 0.67 9.1 1.5 0.97 8.6 1.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 EGG20791.1 - 1.9 6.7 12.0 3.2 5.9 12.0 1.3 1 0 0 1 1 1 0 CDC45-like protein FNIP PF05725.12 EGG20792.1 - 8.2e-10 38.7 31.2 0.00025 21.1 0.4 8.7 7 2 1 9 9 9 4 FNIP Repeat LRR_8 PF13855.6 EGG20792.1 - 0.024 14.4 3.9 0.25 11.2 0.3 3.6 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.7 EGG20792.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EGG20792.1 - 0.043 13.7 0.1 0.16 11.9 0.1 1.9 1 0 0 1 1 1 0 F-box domain Apc13p PF05839.11 EGG20793.1 - 4.8e-05 23.5 0.9 0.00076 19.6 0.9 2.0 1 1 0 1 1 1 1 Apc13p protein CorA PF01544.18 EGG20794.1 - 1.4e-58 198.6 5.7 3.4e-58 197.3 5.7 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Stn1_C PF12659.7 EGG20794.1 - 0.8 9.7 6.0 0.88 9.5 0.2 3.4 3 1 1 4 4 4 0 Telomere capping C-terminal wHTH RRM_1 PF00076.22 EGG20795.1 - 2e-42 142.8 2.3 2.2e-13 49.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG20795.1 - 2e-06 27.8 0.9 0.21 11.8 0.0 3.7 3 1 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 EGG20795.1 - 0.011 15.9 1.2 0.26 11.5 0.0 2.8 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter SLAM PF06214.11 EGG20795.1 - 0.049 13.6 0.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein PhetRS_B1 PF18262.1 EGG20795.1 - 0.061 13.6 0.0 2.1 8.6 0.0 3.0 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain Mucin PF01456.17 EGG20795.1 - 0.63 10.0 18.2 0.52 10.3 14.3 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein SO_alpha_A3 PF17806.1 EGG20795.1 - 0.65 10.4 2.8 4 7.8 0.1 3.1 3 0 0 3 3 3 0 Sarcosine oxidase A3 domain Nup35_RRM PF05172.13 EGG20795.1 - 0.73 9.8 5.6 1.5 8.8 0.5 3.2 2 2 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ribosomal_L3 PF00297.22 EGG20796.1 - 1.4e-13 50.6 8.3 4e-13 49.1 1.8 2.7 1 1 1 3 3 3 2 Ribosomal protein L3 DUF202 PF02656.15 EGG20797.1 - 1.9e-07 31.4 6.0 3.3e-07 30.6 6.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Cwf_Cwc_15 PF04889.12 EGG20797.1 - 0.0047 16.7 28.4 0.0047 16.7 28.4 2.9 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein MCM3AP_GANP PF16769.5 EGG20797.1 - 0.1 10.8 11.8 0.2 9.9 11.8 1.3 1 0 0 1 1 1 0 MCM3AP domain of GANP DUF1084 PF06454.11 EGG20797.1 - 0.14 11.6 1.0 0.2 11.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) Glycogen_syn PF05693.13 EGG20798.1 - 7.7e-121 404.7 0.2 1.3e-120 403.9 0.2 1.3 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 EGG20798.1 - 0.00031 20.3 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGG20798.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Menin PF05053.13 EGG20798.1 - 9.1 4.5 8.3 13 4.0 8.3 1.2 1 0 0 1 1 1 0 Menin Glycogen_syn PF05693.13 EGG20800.1 - 2.1e-15 56.4 0.0 2.4e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase tRNA-synt_2b PF00587.25 EGG20801.1 - 1.8e-21 76.9 0.1 2.8e-21 76.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) fn3 PF00041.21 EGG20801.1 - 4.3e-10 39.8 20.0 0.011 16.0 1.0 6.8 6 1 0 6 6 6 4 Fibronectin type III domain EGF_2 PF07974.13 EGG20801.1 - 0.0039 17.5 11.5 0.017 15.5 11.5 2.3 1 0 0 1 1 1 1 EGF-like domain Seryl_tRNA_N PF02403.22 EGG20801.1 - 0.0049 17.1 0.8 0.01 16.1 0.8 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Imm5 PF14423.6 EGG20801.1 - 0.034 14.4 3.3 0.073 13.3 3.3 1.5 1 0 0 1 1 1 0 Immunity protein Imm5 DUF2369 PF10179.9 EGG20801.1 - 4.3 7.8 9.3 2.8 8.4 0.5 3.8 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) EGF PF00008.27 EGG20801.1 - 6.6 7.1 14.1 0.98 9.8 7.2 3.0 2 0 0 2 2 2 0 EGF-like domain DUF1084 PF06454.11 EGG20802.1 - 2.8e-06 26.9 26.1 5.9e-06 25.9 26.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Oxidored_q2 PF00420.24 EGG20802.1 - 0.042 13.5 2.4 0.14 11.8 2.4 1.9 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ribonuc_red_sm PF00268.21 EGG20803.1 - 1.2e-122 408.7 2.5 1.5e-122 408.5 2.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 EGG20803.1 - 0.083 13.7 0.3 3.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4744) Peptidase_C97 PF05903.14 EGG20805.1 - 1.1e-29 103.2 0.0 2.6e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4611 PF15387.6 EGG20805.1 - 0.01 16.1 6.4 0.022 15.0 6.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) SVIP PF15811.5 EGG20805.1 - 0.47 10.9 6.1 1.1 9.7 6.1 1.6 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Chromo_2 PF18704.1 EGG20805.1 - 0.64 10.3 3.9 1.3 9.3 3.9 1.5 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 PBP_sp32 PF07222.12 EGG20805.1 - 1.5 8.3 6.5 2.3 7.6 6.5 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 NOA36 PF06524.12 EGG20805.1 - 3.4 6.9 8.2 5.3 6.3 8.2 1.2 1 0 0 1 1 1 0 NOA36 protein Alpha-amylase PF00128.24 EGG20806.1 - 3.6e-80 270.0 0.0 1.2e-79 268.3 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, catalytic domain BLM10_mid PF16507.5 EGG20806.1 - 5.4e-46 157.3 10.0 1e-44 153.1 10.0 2.7 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EGG20806.1 - 2.2e-26 91.6 0.3 6.9e-25 86.8 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) Malt_amylase_C PF16657.5 EGG20806.1 - 7.4e-09 35.6 0.0 3.8e-06 26.9 0.0 2.8 2 0 0 2 2 2 2 Maltogenic Amylase, C-terminal domain CLASP_N PF12348.8 EGG20806.1 - 4.2e-05 23.2 0.9 0.015 14.9 1.5 3.4 1 1 1 2 2 2 1 CLASP N terminal U3snoRNP10 PF12397.8 EGG20806.1 - 0.00035 20.9 1.0 1.3 9.4 0.4 5.0 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 ATF7IP_BD PF16788.5 EGG20806.1 - 0.019 15.1 13.0 0.05 13.7 13.0 1.8 1 0 0 1 1 1 0 ATF-interacting protein binding domain SapB_1 PF05184.15 EGG20807.1 - 6.9e-20 70.7 4.8 2.5e-11 43.4 0.0 3.7 4 0 0 4 4 4 2 Saposin-like type B, region 1 SapB_2 PF03489.17 EGG20807.1 - 8.9e-17 60.9 8.6 5.9e-09 35.9 1.6 3.0 2 0 0 2 2 2 2 Saposin-like type B, region 2 TPP_enzyme_N PF02776.18 EGG20809.1 - 2.1e-37 128.4 0.0 5.1e-36 123.9 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGG20809.1 - 1.6e-27 95.9 0.0 2.6e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EGG20809.1 - 1.7e-20 73.4 0.0 3.4e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 EGG20809.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Guanylate_cyc PF00211.20 EGG20810.1 - 9.1e-54 181.8 0.0 1.2e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DAHP_snth_FXD PF18152.1 EGG20810.1 - 0.11 12.3 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain MHYT PF03707.16 EGG20811.1 - 2.7e-33 113.9 21.0 4.7e-14 52.3 1.1 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat Calpain_III PF01067.22 EGG20811.1 - 0.013 15.7 3.5 0.81 9.9 0.1 2.6 2 0 0 2 2 2 0 Calpain large subunit, domain III STAC2_u1 PF16664.5 EGG20811.1 - 0.083 13.3 1.3 0.2 12.1 1.3 1.7 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 LSM PF01423.22 EGG20812.1 - 5.1e-16 58.1 0.3 9.9e-16 57.2 0.3 1.4 1 0 0 1 1 1 1 LSM domain Pro_isomerase PF00160.21 EGG20813.1 - 9.5e-10 39.0 0.0 1.5e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WASH-7_N PF14745.6 EGG20814.1 - 3e-192 640.2 7.4 4.5e-192 639.6 7.4 1.3 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.6 EGG20814.1 - 1.3e-150 501.3 6.4 2.7e-150 500.2 6.4 1.6 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.6 EGG20814.1 - 3.3e-62 209.3 4.2 9.2e-62 207.8 4.2 1.8 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal Gag_MA PF01140.19 EGG20816.1 - 0.03 14.0 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Matrix protein (MA), p15 PI3Ka PF00613.20 EGG20817.1 - 2.5e-47 160.7 3.9 5.3e-47 159.6 3.9 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGG20817.1 - 8.4e-46 156.8 0.1 4.9e-45 154.3 0.1 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EGG20817.1 - 1.8e-10 40.9 0.1 4.4e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 EGG20817.1 - 1.5e-07 31.5 1.4 4.2e-07 30.1 1.4 1.8 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 EGG20817.1 - 0.00068 19.1 0.0 0.0021 17.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4135) RWP-RK PF02042.15 EGG20818.1 - 8.7e-06 25.6 0.2 1.7e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 RWP-RK domain WD40 PF00400.32 EGG20819.1 - 1.5e-18 66.8 6.7 2e-06 28.4 0.6 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG20819.1 - 4.2e-08 33.4 0.1 0.071 13.4 0.1 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG20819.1 - 0.0017 18.2 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGG20819.1 - 0.029 13.7 0.4 11 5.2 0.0 3.1 4 0 0 4 4 4 0 WD40-like domain PD40 PF07676.12 EGG20819.1 - 0.12 12.4 0.0 31 4.7 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DEP PF00610.21 EGG20821.1 - 1.4e-15 57.1 0.1 2.9e-06 27.2 0.0 3.3 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Roc PF08477.13 EGG20822.1 - 3e-08 33.9 0.0 4.4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase HNH PF01844.23 EGG20822.1 - 4.7 7.5 6.6 0.4 10.9 1.7 1.7 2 0 0 2 2 2 0 HNH endonuclease Pkinase_Tyr PF07714.17 EGG20823.1 - 4.2e-48 163.9 0.0 5.7e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG20823.1 - 2.6e-41 141.7 0.0 4e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 EGG20823.1 - 0.00028 20.8 0.0 0.0012 18.7 0.0 2.0 3 0 0 3 3 3 1 C-terminal of Roc, COR, domain Pox_I6 PF04595.13 EGG20823.1 - 0.0042 16.1 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 Poxvirus I6-like family Sgf11 PF08209.11 EGG20824.1 - 2e-09 36.8 1.5 3.5e-09 36.0 1.5 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Med3 PF11593.8 EGG20824.1 - 0.0002 20.7 18.2 0.0002 20.7 18.2 7.1 2 1 3 6 6 6 1 Mediator complex subunit 3 fungal zf-C2HC_2 PF13913.6 EGG20824.1 - 0.0011 18.8 0.8 0.0018 18.1 0.8 1.4 1 0 0 1 1 1 1 zinc-finger of a C2HC-type ANAPC4_WD40 PF12894.7 EGG20826.1 - 3.9e-08 33.5 0.4 0.0058 16.9 0.0 5.2 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG20826.1 - 0.0053 17.6 9.1 16 6.6 0.1 5.6 7 0 0 7 7 7 2 WD domain, G-beta repeat IKI3 PF04762.12 EGG20826.1 - 0.11 10.5 0.1 9.3 4.1 0.1 2.1 1 1 1 2 2 2 0 IKI3 family Gmad1 PF10647.9 EGG20826.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain EGF_2 PF07974.13 EGG20827.1 - 0.004 17.5 10.5 0.0095 16.3 10.5 1.6 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 EGG20827.1 - 0.012 15.9 8.4 0.035 14.4 8.4 1.8 1 0 0 1 1 1 0 EB module hEGF PF12661.7 EGG20827.1 - 0.044 14.4 8.0 0.18 12.5 8.0 2.2 1 0 0 1 1 1 0 Human growth factor-like EGF EB PF01683.18 EGG20828.1 - 0.00044 20.5 3.2 0.0012 19.1 3.2 1.7 1 0 0 1 1 1 1 EB module EGF_2 PF07974.13 EGG20828.1 - 0.012 16.0 10.5 0.026 14.9 10.5 1.6 1 0 0 1 1 1 0 EGF-like domain DUF3042 PF11240.8 EGG20828.1 - 0.16 12.0 3.0 0.34 11.0 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) hEGF PF12661.7 EGG20828.1 - 2.2 9.0 12.1 1.4 9.6 9.2 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF Metallothio_5 PF02067.15 EGG20828.1 - 5.7 7.1 8.6 14 5.9 8.6 1.6 1 0 0 1 1 1 0 Metallothionein family 5 DUF730 PF05325.11 EGG20829.1 - 0.034 14.2 0.5 0.039 14.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF730) EGF_2 PF07974.13 EGG20830.1 - 0.00016 22.0 28.8 0.02 15.3 10.5 2.6 2 0 0 2 2 2 2 EGF-like domain LapA_dom PF06305.11 EGG20830.1 - 0.001 18.8 0.9 0.45 10.4 0.1 2.7 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain CD34_antigen PF06365.12 EGG20830.1 - 0.0078 15.8 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 1 CD34/Podocalyxin family Protocadherin PF08374.11 EGG20830.1 - 0.01 15.8 0.2 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Protocadherin AHD PF17793.1 EGG20830.1 - 0.014 15.2 0.1 11 5.9 0.0 3.0 2 0 0 2 2 2 0 ANC1 homology domain (AHD) hEGF PF12661.7 EGG20830.1 - 0.023 15.3 23.6 0.38 11.5 8.0 3.4 2 0 0 2 2 2 0 Human growth factor-like EGF Insulin_TMD PF17870.1 EGG20830.1 - 0.026 14.6 1.2 5.2 7.2 0.1 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment FUSC_2 PF13515.6 EGG20830.1 - 0.13 12.4 0.6 18 5.4 0.1 2.8 2 0 0 2 2 2 0 Fusaric acid resistance protein-like EphA2_TM PF14575.6 EGG20830.1 - 0.14 13.0 2.5 8.5 7.3 0.2 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3042 PF11240.8 EGG20830.1 - 0.55 10.3 9.7 1.3 9.1 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Bacteriocin_II PF01721.18 EGG20830.1 - 0.7 10.1 4.4 19 5.5 0.3 3.1 2 0 0 2 2 2 0 Class II bacteriocin DUF3844 PF12955.7 EGG20830.1 - 1.6 8.9 14.2 7.2 6.8 3.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) PSI_integrin PF17205.3 EGG20830.1 - 4.9 7.0 9.7 7.2 6.4 0.1 3.7 4 0 0 4 4 4 0 Integrin plexin domain EB PF01683.18 EGG20831.1 - 0.0035 17.6 4.8 0.0084 16.4 4.8 1.6 1 0 0 1 1 1 1 EB module EGF_2 PF07974.13 EGG20831.1 - 0.042 14.2 8.2 0.09 13.2 8.2 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EGG20831.1 - 1.4 9.0 6.3 3.5 7.8 6.3 1.6 1 0 0 1 1 1 0 Tenascin EGF domain EGF_2 PF07974.13 EGG20832.1 - 0.0061 16.9 10.5 0.013 15.9 10.5 1.5 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 EGG20832.1 - 0.027 14.7 9.0 0.068 13.5 9.0 1.6 1 0 0 1 1 1 0 EB module hEGF PF12661.7 EGG20832.1 - 0.077 13.7 8.0 0.24 12.1 8.0 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF DUF3042 PF11240.8 EGG20832.1 - 4.3 7.5 5.8 12 6.1 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Ank_4 PF13637.6 EGG20833.1 - 8.1e-12 45.4 4.1 0.0017 18.9 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG20833.1 - 5.7e-11 42.9 5.9 0.00018 22.0 0.2 4.0 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG20833.1 - 6e-09 36.0 3.3 0.022 15.1 0.0 6.0 3 2 4 7 7 7 2 Ankyrin repeats (many copies) DUF5049 PF16468.5 EGG20833.1 - 0.00015 21.6 0.2 0.3 11.0 0.1 4.3 3 1 1 4 4 4 1 Domain of unknown function (DUF5049) Ank_3 PF13606.6 EGG20833.1 - 0.057 14.0 4.2 3.5e+02 2.3 0.0 6.3 5 2 2 7 7 7 0 Ankyrin repeat Nfu_N PF08712.11 EGG20834.1 - 6.5e-30 103.0 1.1 3.7e-28 97.4 0.0 2.5 2 0 0 2 2 2 2 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EGG20834.1 - 2.5e-24 85.2 0.0 4.2e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain E1_DerP2_DerF2 PF02221.15 EGG20835.1 - 5.3e-25 88.4 0.3 6e-25 88.2 0.3 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EGG20835.1 - 4.9e-06 27.0 0.4 9.1e-06 26.1 0.4 1.4 1 1 0 1 1 1 1 ML-like domain DUF4625 PF15418.6 EGG20835.1 - 0.0026 18.0 0.0 0.0047 17.2 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4625) Arrestin_N PF00339.29 EGG20835.1 - 0.018 15.1 0.0 0.065 13.3 0.0 1.8 1 1 1 2 2 2 0 Arrestin (or S-antigen), N-terminal domain DUF4832 PF16116.5 EGG20835.1 - 0.13 12.1 0.0 0.75 9.6 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4832) DUF2808 PF10989.8 EGG20835.1 - 0.17 11.8 0.6 9.1 6.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) Coq4 PF05019.13 EGG20836.1 - 3.6e-84 281.5 0.0 4.8e-84 281.1 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Fer4_6 PF12837.7 EGG20838.1 - 0.11 12.7 1.2 0.24 11.5 1.2 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain RasGEF PF00617.19 EGG20840.1 - 5e-49 166.9 1.3 8.8e-49 166.1 1.3 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGG20840.1 - 3.1e-11 43.5 0.0 3.1e-11 43.5 0.0 2.9 2 1 0 2 2 2 1 RasGEF N-terminal motif cNMP_binding PF00027.29 EGG20840.1 - 2.2e-05 24.4 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Tae4 PF14113.6 EGG20840.1 - 0.0072 16.5 0.0 0.047 13.9 0.0 2.2 2 0 0 2 2 2 1 Type VI secretion system (T6SS), amidase effector protein 4 DUF4834 PF16118.5 EGG20842.1 - 0.0012 19.8 0.9 0.004 18.1 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) DUF3332 PF11810.8 EGG20842.1 - 0.027 14.1 0.2 0.045 13.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) HemY_N PF07219.13 EGG20842.1 - 0.28 11.4 0.1 0.28 11.4 0.1 1.7 2 0 0 2 2 2 0 HemY protein N-terminus SPT16 PF08644.11 EGG20843.1 - 4e-50 169.9 0.8 4e-50 169.9 0.8 3.9 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EGG20843.1 - 2.2e-44 151.1 2.2 2.2e-44 151.1 2.2 2.7 2 1 1 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EGG20843.1 - 5.8e-29 101.3 0.0 9.1e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EGG20843.1 - 2.1e-13 50.5 3.3 4e-13 49.6 0.3 2.5 2 0 0 2 2 2 1 Histone chaperone Rttp106-like RhoGEF PF00621.20 EGG20844.1 - 2e-45 155.3 4.8 5.5e-45 153.8 4.8 1.8 1 0 0 1 1 1 1 RhoGEF domain Aa_trans PF01490.18 EGG20844.1 - 7e-14 51.3 31.6 1.6e-13 50.2 31.6 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein CH PF00307.31 EGG20844.1 - 3.6e-10 40.0 0.0 2.1e-09 37.5 0.0 2.4 1 0 0 1 1 1 1 Calponin homology (CH) domain PX PF00787.24 EGG20844.1 - 5.8e-10 39.2 1.1 5.8e-10 39.2 1.1 2.2 2 0 0 2 2 2 1 PX domain CH_2 PF06294.11 EGG20844.1 - 0.068 13.3 0.0 0.33 11.1 0.0 2.3 1 0 0 1 1 1 0 CH-like domain in sperm protein LRR_6 PF13516.6 EGG20845.1 - 0.021 14.8 6.3 15 5.9 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.7 EGG20845.1 - 2.6 8.6 25.1 0.61 10.6 0.2 5.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) cNMP_binding PF00027.29 EGG20846.1 - 1.2e-34 118.3 0.0 2.1e-17 63.0 0.0 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Lactamase_B_2 PF12706.7 EGG20846.1 - 3.6e-09 36.4 0.0 6.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGG20846.1 - 2.1e-05 24.6 0.0 3.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EGG20846.1 - 0.01 15.7 0.2 0.045 13.6 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase superfamily domain SUIM_assoc PF16619.5 EGG20846.1 - 0.088 12.9 6.3 0.24 11.5 6.3 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ICEA PF05315.11 EGG20847.1 - 0.076 12.5 0.8 0.14 11.6 0.8 1.6 1 1 0 1 1 1 0 ICEA Protein FtsJ PF01728.19 EGG20849.1 - 9.9e-11 42.1 0.0 1.8e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase CHMI PF02962.15 EGG20849.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 5-carboxymethyl-2-hydroxymuconate isomerase Sad1_UNC PF07738.13 EGG20850.1 - 2.7e-32 111.6 0.5 2.7e-32 111.6 0.5 1.8 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal DUF4231 PF14015.6 EGG20850.1 - 0.0087 16.5 0.2 0.022 15.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4231) Syndecan PF01034.20 EGG20851.1 - 0.013 15.4 0.0 0.039 13.9 0.0 1.7 1 0 0 1 1 1 0 Syndecan domain Med13_C PF06333.12 EGG20852.1 - 2.4 7.3 14.3 0.43 9.8 7.4 2.1 1 1 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain FliE PF02049.18 EGG20854.1 - 0.17 12.1 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE DNA_pol_phi PF04931.13 EGG20855.1 - 4.1 5.4 47.5 3.9 5.5 47.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi RelA_SpoT PF04607.17 EGG20857.1 - 1.2e-28 99.8 0.1 2.7e-28 98.6 0.1 1.6 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins FA_desaturase PF00487.24 EGG20857.1 - 0.004 17.0 1.3 0.0065 16.3 1.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyclophil_like2 PF18050.1 EGG20857.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Cyclophilin-like family ATG7_N PF16420.5 EGG20858.1 - 6.4e-88 295.3 0.1 1.3e-87 294.3 0.3 1.4 2 0 0 2 2 2 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EGG20858.1 - 2.7e-40 138.3 0.0 3.9e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EGG20858.1 - 0.078 13.0 0.0 3 7.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EGG20858.1 - 0.13 11.9 0.0 0.79 9.4 0.0 2.0 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA zf-CCCH PF00642.24 EGG20859.1 - 2.3e-14 52.9 14.1 8.1e-10 38.4 5.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGG20859.1 - 2.8e-08 33.4 7.1 2.3e-06 27.2 2.4 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGG20859.1 - 3e-07 30.3 11.1 0.00043 20.2 5.7 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 EGG20859.1 - 0.88 10.1 4.4 0.24 12.0 0.7 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger NYD-SP28_assoc PF14775.6 EGG20860.1 - 0.087 12.9 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain Ribosomal_L37e PF01907.19 EGG20861.1 - 3.8e-26 91.0 10.3 6.6e-26 90.2 10.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.18 EGG20861.1 - 0.009 16.1 0.3 0.013 15.5 0.3 1.3 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 EGG20861.1 - 0.039 14.0 1.3 0.075 13.1 1.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 EGG20861.1 - 0.14 12.2 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NAP PF00956.18 EGG20862.1 - 1.5e-14 53.8 29.0 3e-12 46.3 28.3 4.1 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Phi-29_GP4 PF05464.11 EGG20862.1 - 0.12 12.7 0.2 0.2 11.9 0.2 1.3 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Amelin PF05111.12 EGG20862.1 - 0.52 9.4 10.0 0.69 9.0 10.0 1.1 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) Ndc1_Nup PF09531.10 EGG20862.1 - 2.4 6.7 8.1 2.6 6.6 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC1 PF03109.16 EGG20863.1 - 4.1e-34 117.3 0.0 1.1e-33 115.9 0.0 1.8 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EGG20863.1 - 0.0045 16.4 0.2 0.011 15.2 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain MecA PF05389.12 EGG20863.1 - 0.037 13.7 3.9 0.12 12.0 3.9 1.8 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) NOA36 PF06524.12 EGG20863.1 - 0.23 10.7 1.6 0.43 9.9 1.6 1.3 1 0 0 1 1 1 0 NOA36 protein Di19_C PF14571.6 EGG20863.1 - 0.36 11.4 5.5 1.2 9.7 5.5 2.0 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal HAD_2 PF13419.6 EGG20864.1 - 0.047 13.8 0.3 0.081 13.0 0.3 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase LIM PF00412.22 EGG20865.1 - 2.4e-23 82.1 66.9 8.9e-08 32.2 10.9 5.6 5 0 0 5 5 5 4 LIM domain PTEN_C2 PF10409.9 EGG20865.1 - 1.8e-22 79.6 1.0 1.8e-22 79.6 1.0 2.2 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 EGG20865.1 - 5e-08 32.8 1.3 1.9e-07 31.0 0.0 2.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG20865.1 - 0.0015 18.2 0.0 0.0015 18.2 0.0 2.4 3 0 0 3 3 3 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGG20865.1 - 0.0048 16.9 0.1 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EGG20865.1 - 0.016 15.3 0.0 0.016 15.3 0.0 2.4 3 0 0 3 3 3 0 Inositol hexakisphosphate PH_5 PF15405.6 EGG20865.1 - 1.2 9.2 6.8 0.66 10.1 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain HalOD2 PF18547.1 EGG20865.1 - 2.3 8.2 6.5 0.48 10.4 1.0 2.9 3 0 0 3 3 3 0 Halobacterial output domain 2 Ndc1_Nup PF09531.10 EGG20865.1 - 5.4 5.6 10.5 0.13 11.0 4.2 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Mito_carr PF00153.27 EGG20866.1 - 8.9e-59 195.4 1.6 1.4e-18 66.6 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DHHC PF01529.20 EGG20866.1 - 7.6e-36 123.2 4.1 7.6e-36 123.2 4.1 2.8 3 0 0 3 3 3 1 DHHC palmitoyltransferase FtsX PF02687.21 EGG20866.1 - 0.07 13.6 4.3 0.3 11.6 4.3 2.1 1 0 0 1 1 1 0 FtsX-like permease family LRAT PF04970.13 EGG20867.1 - 0.00095 19.5 0.9 0.018 15.4 0.9 2.1 1 1 0 1 1 1 1 Lecithin retinol acyltransferase BB_PF PF18063.1 EGG20869.1 - 5.8e-43 146.9 0.0 7.7e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Beta barrel Pore-forming domain TrmO PF01980.16 EGG20870.1 - 8.6e-37 126.0 0.4 9.3e-24 83.9 0.1 2.6 2 0 0 2 2 2 2 tRNA-methyltransferase O CDC45 PF02724.14 EGG20870.1 - 0.0025 16.2 16.1 0.0053 15.1 16.1 1.4 1 0 0 1 1 1 1 CDC45-like protein TrmO_C PF18389.1 EGG20870.1 - 0.0034 17.5 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 TrmO C-terminal domain Zip PF02535.22 EGG20870.1 - 0.008 15.4 0.6 0.013 14.7 0.6 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter CDC27 PF09507.10 EGG20870.1 - 0.3 10.5 19.4 0.52 9.6 19.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sporozoite_P67 PF05642.11 EGG20870.1 - 0.48 8.4 14.7 0.016 13.4 8.6 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen 2OG-FeII_Oxy_2 PF13532.6 EGG20871.1 - 8.1e-41 140.4 0.0 2.3e-39 135.7 0.0 2.7 2 1 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily HSP90 PF00183.18 EGG20872.1 - 2.8e-177 590.7 22.9 3.8e-177 590.3 22.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 EGG20872.1 - 1.8e-10 40.8 0.2 5.7e-10 39.2 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGG20872.1 - 1.2e-09 38.6 0.2 2.3e-09 37.7 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Spore_coat_CotO PF14153.6 EGG20872.1 - 1 9.3 14.8 0.82 9.6 12.0 2.2 2 0 0 2 2 2 0 Spore coat protein CotO CobT PF06213.12 EGG20872.1 - 6.7 6.0 10.9 15 4.9 10.9 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 EGG20872.1 - 9.6 5.4 7.8 17 4.6 7.8 1.3 1 0 0 1 1 1 0 NOA36 protein Aminotran_5 PF00266.19 EGG20873.1 - 9.9e-42 143.2 0.0 1.2e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V TPR_5 PF12688.7 EGG20873.1 - 0.07 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetratrico peptide repeat VPS9 PF02204.18 EGG20874.1 - 5.1e-11 42.7 0.0 1.7e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Glycos_transf_1 PF00534.20 EGG20875.1 - 3.3e-07 30.0 0.0 3.7e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGG20875.1 - 4.2e-05 24.0 0.0 0.00062 20.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGG20875.1 - 0.0091 16.0 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGG20875.1 - 0.014 15.9 0.0 0.019 15.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain zf-C3HC4_3 PF13920.6 EGG20876.1 - 0.004 17.0 10.0 0.004 17.0 10.0 4.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) HNF-1_N PF04814.13 EGG20876.1 - 0.0042 17.7 9.1 0.0042 17.7 9.1 4.8 3 2 2 5 5 5 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus zf-C2HE PF16278.5 EGG20876.1 - 0.019 15.4 0.6 0.019 15.4 0.6 3.7 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger GCP_N_terminal PF17681.1 EGG20877.1 - 0.027 14.1 0.1 0.062 12.9 0.1 1.6 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal Ank_2 PF12796.7 EGG20879.1 - 5.8e-36 122.9 10.7 9e-08 32.6 0.1 6.4 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG20879.1 - 3.5e-32 110.0 13.5 0.0014 18.8 0.1 11.1 4 4 7 11 11 11 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG20879.1 - 1.2e-30 105.5 7.9 4.3e-05 24.0 0.0 9.5 6 4 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG20879.1 - 2.8e-20 70.2 0.6 0.033 14.7 0.0 12.9 11 3 3 14 14 14 2 Ankyrin repeat Ank PF00023.30 EGG20879.1 - 2.8e-05 24.4 5.3 5.4 7.6 0.0 8.5 7 5 2 9 9 9 1 Ankyrin repeat Linker_histone PF00538.19 EGG20879.1 - 0.0099 16.2 0.5 1.9 8.9 0.0 4.5 5 0 0 5 5 5 1 linker histone H1 and H5 family DUF1843 PF08898.10 EGG20879.1 - 0.029 14.9 0.0 27 5.4 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) Ank_2 PF12796.7 EGG20880.1 - 6.2e-42 142.1 6.6 1.4e-06 28.8 0.1 8.6 4 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG20880.1 - 1.9e-35 120.8 10.9 0.001 19.6 0.0 14.5 9 3 4 14 14 14 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG20880.1 - 1.5e-22 79.3 7.7 1.1 9.6 0.0 15.3 6 4 10 17 17 17 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG20880.1 - 1.2e-18 65.2 5.6 1.5 9.6 0.0 15.2 18 0 0 18 18 18 3 Ankyrin repeat DUF5049 PF16468.5 EGG20880.1 - 1.6e-06 27.9 1.5 7 6.6 0.0 7.1 7 1 1 8 8 8 2 Domain of unknown function (DUF5049) Ank PF00023.30 EGG20880.1 - 0.00065 20.0 10.1 1.5 9.4 0.0 9.5 9 3 1 10 10 10 1 Ankyrin repeat DUF249 PF03158.13 EGG20880.1 - 0.092 12.5 0.2 2.2 8.0 0.0 3.1 3 1 1 4 4 4 0 Multigene family 530 protein AAA_16 PF13191.6 EGG20881.1 - 0.00059 20.3 0.1 0.0077 16.6 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EGG20881.1 - 0.00083 19.4 0.0 0.0023 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGG20881.1 - 0.0045 16.1 0.0 0.0083 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGG20881.1 - 0.0068 16.7 0.0 0.025 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGG20881.1 - 0.017 14.6 1.1 0.029 13.9 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region NAD_binding_1 PF00175.21 EGG20881.1 - 0.79 10.4 3.3 3.6 8.3 1.1 2.7 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain YecM PF06185.12 EGG20883.1 - 1.7e-54 184.2 0.3 2e-54 184.0 0.3 1.0 1 0 0 1 1 1 1 YecM protein Ribosomal_S28e PF01200.18 EGG20886.1 - 7.5e-23 80.3 0.4 9.9e-23 79.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Mito_carr PF00153.27 EGG20887.1 - 1.5e-77 255.6 1.6 2.3e-24 85.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EGG20887.1 - 9e-12 43.7 3.6 6.5e-06 25.3 1.7 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGG20887.1 - 1e-11 45.1 4.3 1.8e-11 44.3 4.3 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGG20887.1 - 2.8e-09 36.2 3.5 1.3e-05 24.7 1.9 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGG20887.1 - 3.2e-06 26.4 1.3 2.5e-05 23.5 0.8 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGG20887.1 - 3.8e-06 26.6 4.5 0.0079 16.0 0.4 2.4 1 1 1 2 2 2 2 EF-hand domain pair VPS13 PF16908.5 EGG20887.1 - 0.0036 17.1 0.1 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal SPARC_Ca_bdg PF10591.9 EGG20887.1 - 0.0042 17.4 1.1 0.0065 16.8 1.1 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 EGG20887.1 - 0.021 13.4 0.2 0.028 13.0 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Caleosin PF05042.13 EGG20887.1 - 0.064 13.2 0.3 0.2 11.6 0.2 1.9 1 1 0 1 1 1 0 Caleosin related protein EF-hand_14 PF17959.1 EGG20887.1 - 0.075 13.4 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 EF-hand domain Serine_protease PF18405.1 EGG20887.1 - 0.14 11.3 0.5 5.7 6.0 0.0 2.9 4 0 0 4 4 4 0 Gammaproteobacterial serine protease SNF2_N PF00176.23 EGG20888.1 - 5.2e-48 163.6 0.6 1.1e-47 162.5 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG20888.1 - 9.4e-13 48.5 0.0 3.8e-12 46.5 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG20888.1 - 6.1e-11 42.6 0.6 6.1e-11 42.6 0.6 5.2 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit SAM_1 PF00536.30 EGG20888.1 - 0.00053 20.4 0.1 0.00053 20.4 0.1 2.3 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGG20888.1 - 0.11 12.7 0.1 0.11 12.7 0.1 3.0 2 1 1 3 3 3 0 SAM domain (Sterile alpha motif) DUF3015 PF11220.8 EGG20889.1 - 0.013 15.3 1.0 0.013 15.3 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) PLD_C PF12357.8 EGG20889.1 - 0.11 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Phospholipase D C terminal PPR_2 PF13041.6 EGG20890.1 - 1.7e-09 37.7 4.5 0.014 15.6 0.2 5.7 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.6 EGG20890.1 - 5.3e-08 32.8 6.5 0.41 10.8 0.0 6.0 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 EGG20890.1 - 8.9e-07 28.8 3.7 6.1 7.3 0.0 6.9 8 0 0 8 8 8 3 PPR repeat PPR_long PF17177.4 EGG20890.1 - 0.035 13.5 0.0 17 4.7 0.0 3.3 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 EGG20890.1 - 0.037 13.1 0.5 0.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway EF-hand_6 PF13405.6 EGG20892.1 - 4.7e-21 72.9 6.7 1.1e-05 25.0 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EGG20892.1 - 4.2e-20 69.7 10.1 1.9e-05 23.9 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGG20892.1 - 5.4e-19 68.4 4.8 5.9e-11 42.7 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGG20892.1 - 3.9e-12 45.8 7.1 0.00024 20.9 0.1 4.2 2 1 3 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 EGG20892.1 - 2.2e-10 39.5 7.7 0.00065 19.1 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 EGG20892.1 - 1.5e-06 28.0 1.9 0.08 12.9 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGG20892.1 - 0.00028 21.2 1.6 0.18 12.1 0.2 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGG20892.1 - 0.00038 20.7 0.0 0.017 15.5 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain EF-hand_10 PF14788.6 EGG20892.1 - 0.002 18.0 8.0 0.32 10.9 0.0 3.9 4 1 0 4 4 4 2 EF hand Caleosin PF05042.13 EGG20892.1 - 0.018 15.0 3.1 2.8 7.8 0.0 3.3 2 2 1 3 3 3 0 Caleosin related protein DUF4050 PF13259.6 EGG20893.1 - 0.00016 22.1 0.1 0.00024 21.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) Dicty_REP PF05086.12 EGG20894.1 - 0.3 9.0 4.0 0.23 9.4 4.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 EGG20894.1 - 0.37 8.9 5.2 0.36 8.9 5.2 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sporozoite_P67 PF05642.11 EGG20894.1 - 1.1 7.2 5.0 1.1 7.2 5.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 EGG20894.1 - 2.7 8.0 15.9 2.9 7.9 15.9 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Pet100 PF09803.9 EGG20895.1 - 1.7e-08 34.9 0.1 1.7e-08 34.9 0.1 2.0 2 1 0 2 2 2 1 Pet100 Tmemb_9 PF05434.11 EGG20896.1 - 0.0092 15.9 1.3 0.018 14.9 1.3 1.5 1 0 0 1 1 1 1 TMEM9 EF-G-binding_N PF07299.11 EGG20896.1 - 5 7.7 12.2 0.59 10.7 1.8 3.2 4 0 0 4 4 4 0 Elongation factor G-binding protein, N-terminal Vinculin PF01044.19 EGG20897.1 - 7.2e-44 150.3 43.0 2.7e-24 85.5 15.5 3.1 1 1 2 3 3 3 3 Vinculin family DUF4363 PF14276.6 EGG20897.1 - 0.012 15.7 10.9 1.9 8.6 0.4 6.2 6 2 3 9 9 9 0 Domain of unknown function (DUF4363) Mito_morph_reg PF14972.6 EGG20897.1 - 0.2 11.3 3.0 3.1 7.4 0.3 3.0 3 0 0 3 3 3 0 Mitochondrial morphogenesis regulator P53_C PF11619.8 EGG20897.1 - 0.22 11.6 12.8 6.8 6.8 0.2 5.1 4 1 1 5 5 5 0 Transcription factor P53 - C terminal domain Iron_permease PF04120.12 EGG20897.1 - 0.3 10.9 2.9 4.7 7.0 0.1 3.2 3 0 0 3 3 3 0 Low affinity iron permease Syntaxin-6_N PF09177.11 EGG20897.1 - 0.34 11.5 17.2 0.75 10.4 0.6 5.3 6 1 0 6 6 4 0 Syntaxin 6, N-terminal CLTH PF10607.9 EGG20897.1 - 0.42 10.5 2.5 12 5.8 2.4 3.2 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain GLE1 PF07817.13 EGG20897.1 - 0.48 9.6 9.8 0.15 11.2 3.7 2.9 2 1 0 2 2 2 0 GLE1-like protein PilJ PF13675.6 EGG20897.1 - 0.49 10.4 6.8 1.6 8.8 0.6 3.7 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term 4HB_MCP_1 PF12729.7 EGG20897.1 - 1.2 8.7 14.9 0.15 11.6 2.3 4.1 4 0 0 4 4 4 0 Four helix bundle sensory module for signal transduction Peptidase_M75 PF09375.10 EGG20897.1 - 3 7.2 25.4 0.9 9.0 8.2 4.8 3 1 0 3 3 3 0 Imelysin Prominin PF05478.11 EGG20897.1 - 3.7 5.4 17.2 0.29 9.1 5.1 2.5 2 0 0 2 2 2 0 Prominin Hrs_helical PF12210.8 EGG20897.1 - 4.4 7.9 15.0 2.6 8.7 0.6 3.8 3 1 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF5636 PF18686.1 EGG20897.1 - 5.5 7.1 6.6 21 5.2 0.2 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5636) Syntaxin_2 PF14523.6 EGG20897.1 - 5.5 7.4 26.6 2.4 8.6 3.0 5.9 4 2 3 8 8 8 0 Syntaxin-like protein Pup PF05639.11 EGG20897.1 - 7.6 7.5 9.6 15 6.6 0.3 4.1 3 0 0 3 3 3 0 Pup-like protein MIR PF02815.19 EGG20898.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 MIR domain HA2 PF04408.23 EGG20899.1 - 5.3e-24 84.6 0.0 5.3e-24 84.6 0.0 3.9 2 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGG20899.1 - 8.8e-22 77.3 0.2 2.6e-21 75.8 0.2 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGG20899.1 - 2.2e-13 50.5 0.0 7.5e-13 48.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGG20899.1 - 2.3e-05 24.7 0.0 8.1e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EGG20899.1 - 2.4e-05 24.2 0.0 6.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EGG20899.1 - 0.00067 19.4 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGG20899.1 - 0.0039 16.3 0.0 0.011 14.8 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EGG20899.1 - 0.011 16.1 0.0 0.034 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGG20899.1 - 0.43 11.1 0.0 0.43 11.1 0.0 4.0 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 EGG20899.1 - 1.3 9.5 0.0 1.3 9.5 0.0 4.2 2 1 1 3 3 3 0 AAA domain HA2 PF04408.23 EGG20900.1 - 2.2e-20 72.9 0.0 2.2e-20 72.9 0.0 4.2 3 1 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGG20900.1 - 1.3e-14 54.3 0.6 3e-14 53.1 0.0 2.0 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGG20900.1 - 2.5e-13 50.3 0.0 7.8e-13 48.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LRR_6 PF13516.6 EGG20900.1 - 2.8e-11 42.5 12.7 0.00018 21.3 0.1 5.1 5 0 0 5 5 5 3 Leucine Rich repeat DEAD PF00270.29 EGG20900.1 - 1.5e-07 31.4 0.1 4.6e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGG20900.1 - 3.1e-05 24.3 0.0 0.00013 22.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG20900.1 - 0.00081 19.7 0.1 0.0036 17.6 0.1 2.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG20900.1 - 0.0051 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGG20900.1 - 0.068 13.7 1.7 0.18 12.3 0.0 2.7 2 0 0 2 2 2 0 ABC transporter Pox_A32 PF04665.12 EGG20900.1 - 0.069 12.6 0.3 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein T2SSE PF00437.20 EGG20900.1 - 0.07 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.14 EGG20900.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.6 EGG20900.1 - 1.7 8.6 7.6 1.6 8.7 0.7 3.9 3 1 0 3 3 3 0 AAA domain HTH_Tnp_IS630 PF01710.16 EGG20900.1 - 8.1 6.5 10.4 0.43 10.6 2.8 2.6 2 0 0 2 2 2 0 Transposase Ribosomal_S19 PF00203.21 EGG20901.1 - 7.4e-29 99.5 2.2 1e-28 99.0 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TPR_2 PF07719.17 EGG20902.1 - 3.4e-11 42.4 5.9 0.0092 16.0 0.3 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG20902.1 - 5.2e-08 33.3 10.9 0.0007 20.0 0.0 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG20902.1 - 8.2e-08 32.5 0.5 3.3 8.8 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG20902.1 - 5e-07 29.4 5.9 0.0066 16.6 0.3 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG20902.1 - 2.5e-06 28.0 0.1 0.13 12.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG20902.1 - 3.4e-06 27.2 9.8 0.00062 20.0 0.2 4.3 3 2 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG20902.1 - 1.1e-05 25.3 0.0 0.1 12.7 0.0 3.0 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 EGG20902.1 - 1.3e-05 24.8 17.9 0.0097 15.7 1.2 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat MIT PF04212.18 EGG20902.1 - 0.00025 21.1 9.2 0.42 10.7 0.5 4.9 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 EGG20902.1 - 0.012 15.8 5.8 6.6 7.0 1.5 3.7 3 1 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 S_100 PF01023.19 EGG20902.1 - 0.029 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain TPR_6 PF13174.6 EGG20902.1 - 0.029 15.0 0.1 1.1e+02 3.8 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat NARP1 PF12569.8 EGG20902.1 - 0.029 13.3 5.1 0.84 8.5 0.1 3.9 3 1 1 5 5 5 0 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 EGG20902.1 - 0.048 13.7 1.2 2.9 8.1 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGG20902.1 - 0.05 12.8 1.3 0.25 10.5 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGG20902.1 - 0.081 13.4 0.0 7.5 7.0 0.1 2.6 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation H_lectin PF09458.10 EGG20902.1 - 0.085 13.1 1.9 0.19 11.9 1.9 1.6 1 0 0 1 1 1 0 H-type lectin domain DUF1993 PF09351.10 EGG20902.1 - 0.12 12.5 0.9 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) DUF4164 PF13747.6 EGG20902.1 - 0.15 12.4 0.3 0.73 10.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) CHASE3 PF05227.13 EGG20902.1 - 0.53 10.2 3.2 5.4 6.9 0.7 3.2 3 1 0 3 3 3 0 CHASE3 domain TPR_11 PF13414.6 EGG20902.1 - 2.3 8.0 16.7 1.3 8.8 0.4 4.8 6 1 0 6 6 6 0 TPR repeat Peptidase_C1 PF00112.23 EGG20903.1 - 4.5e-53 180.5 5.1 5.5e-53 180.3 5.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Ribosomal_L6e PF01159.19 EGG20904.1 - 6.4e-35 120.1 6.4 6.4e-35 120.1 6.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L6e ROS_MUCR PF05443.11 EGG20904.1 - 0.19 11.8 3.0 0.53 10.3 0.2 2.2 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein DUF2838 PF10998.8 EGG20905.1 - 2.6e-10 40.5 0.2 2.6e-10 40.5 0.2 3.2 3 1 1 4 4 4 2 Protein of unknown function (DUF2838) MFMR_assoc PF16596.5 EGG20905.1 - 0.022 15.2 12.3 0.022 15.2 12.3 1.9 2 0 0 2 2 2 0 Disordered region downstream of MFMR Menin PF05053.13 EGG20905.1 - 2.1 6.6 4.9 3.2 6.0 4.9 1.3 1 0 0 1 1 1 0 Menin CLPTM1 PF05602.12 EGG20906.1 - 2.3e-134 448.7 8.6 2.3e-134 448.7 8.6 1.9 2 0 0 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EGG20906.1 - 0.0004 20.1 1.5 0.32 10.8 0.3 2.7 2 0 0 2 2 2 2 PQ loop repeat PIEZO PF15917.5 EGG20906.1 - 1.6 8.1 8.7 5.9 6.3 8.2 2.1 2 0 0 2 2 2 0 Piezo Rho_N PF07498.12 EGG20910.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain RRM_1 PF00076.22 EGG20912.1 - 0.0067 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pentapeptide_4 PF13599.6 EGG20913.1 - 0.08 13.1 0.2 1.5 9.1 0.0 2.6 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) LRR_1 PF00560.33 EGG20913.1 - 0.15 12.7 1.2 2.2 9.2 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 EGG20913.1 - 3.6 7.9 8.9 0.49 10.6 0.6 3.5 4 0 0 4 4 4 0 Leucine Rich repeat TATR PF03430.13 EGG20914.1 - 1.3 7.3 7.4 1.6 7.0 7.4 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator BES1_N PF05687.13 EGG20914.1 - 3.6 7.9 10.7 4.4 7.7 10.7 1.2 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal PAP1 PF08601.10 EGG20914.1 - 5.2 6.7 15.1 5.8 6.5 15.1 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 RGCC PF15151.6 EGG20914.1 - 6.3 7.0 11.1 7.7 6.7 11.1 1.1 1 0 0 1 1 1 0 Response gene to complement 32 protein family FAM199X PF15814.5 EGG20914.1 - 8.7 5.3 13.5 9.7 5.1 13.5 1.1 1 0 0 1 1 1 0 Protein family FAM199X ADH_zinc_N PF00107.26 EGG20915.1 - 1.6e-29 102.5 0.1 2.5e-29 101.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGG20915.1 - 2.8e-19 70.5 0.0 5.5e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG20915.1 - 5.5e-08 32.7 0.0 1.6e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EGG20915.1 - 0.038 13.9 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DUF4170 PF13773.6 EGG20916.1 - 0.061 13.5 0.1 0.98 9.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4170) RhoGEF PF00621.20 EGG20917.1 - 4.4e-38 131.3 1.9 4.4e-38 131.3 1.9 2.9 2 1 1 3 3 3 1 RhoGEF domain IQ PF00612.27 EGG20917.1 - 0.0023 17.6 2.0 0.007 16.1 2.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif I_LWEQ PF01608.17 EGG20917.1 - 0.95 9.7 11.9 0.59 10.4 6.8 3.0 1 1 1 2 2 2 0 I/LWEQ domain Mob1_phocein PF03637.17 EGG20918.1 - 2.8e-79 265.0 0.1 3.3e-79 264.8 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family RRM_1 PF00076.22 EGG20919.1 - 1.9e-17 62.8 0.0 3.2e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGG20919.1 - 0.00045 20.2 0.0 0.00082 19.4 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif FtsX PF02687.21 EGG20920.1 - 8.4e-15 55.0 23.0 1.1e-08 35.4 4.9 7.0 7 1 0 7 7 7 2 FtsX-like permease family Peptidase_C16 PF01831.17 EGG20920.1 - 0.0072 16.1 0.1 0.015 15.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase C16 family TPR_1 PF00515.28 EGG20921.1 - 2.4e-48 160.1 32.4 8.4e-09 34.9 0.1 10.4 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 EGG20921.1 - 3.9e-40 132.7 25.9 6.1e-07 29.1 0.1 10.2 9 1 0 9 9 9 7 Tetratricopeptide repeat STI1 PF17830.1 EGG20921.1 - 7e-34 115.5 2.1 1.7e-16 59.9 0.0 2.6 2 0 0 2 2 2 2 STI1 domain TPR_12 PF13424.6 EGG20921.1 - 2.5e-25 88.6 5.8 1.6e-05 25.1 0.1 6.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGG20921.1 - 6e-22 78.0 0.4 3.3e-08 34.0 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGG20921.1 - 6.6e-22 76.9 19.8 2e-08 33.8 0.0 7.0 6 2 1 7 7 7 4 TPR repeat TPR_8 PF13181.6 EGG20921.1 - 7.5e-22 75.7 26.5 0.00063 19.8 0.2 9.3 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGG20921.1 - 4.3e-17 61.3 0.2 0.17 12.8 0.0 8.4 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG20921.1 - 2e-15 57.0 14.3 0.00035 21.0 0.8 6.7 5 2 1 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGG20921.1 - 3.7e-13 48.5 6.4 0.055 13.5 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGG20921.1 - 3.3e-12 45.9 14.9 0.0026 18.0 0.0 7.0 8 0 0 8 8 6 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG20921.1 - 1.5e-10 41.0 11.1 0.0018 18.3 0.1 5.8 6 0 0 6 6 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EGG20921.1 - 6.1e-10 38.7 10.4 0.32 10.9 0.1 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGG20921.1 - 2.2e-06 27.7 0.0 0.096 12.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG20921.1 - 3.9e-05 23.8 16.0 0.0097 16.1 1.7 4.3 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGG20921.1 - 0.00025 21.5 14.1 1.7 9.4 0.0 6.7 9 0 0 9 9 5 2 Tetratricopeptide repeat DUF5113 PF17140.4 EGG20921.1 - 0.00056 19.8 4.8 1.9 8.2 0.3 4.0 3 1 1 4 4 4 2 Domain of unknown function (DUF5113) TPR_15 PF13429.6 EGG20921.1 - 0.013 14.8 4.3 2.4 7.3 0.1 4.2 3 2 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EGG20921.1 - 0.027 14.5 1.2 0.027 14.5 1.2 6.4 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 EGG20921.1 - 0.029 14.8 1.3 32 4.9 0.1 4.1 2 1 1 4 4 4 0 Bacterial transcriptional activator domain SHNi-TPR PF10516.9 EGG20921.1 - 0.056 12.9 2.0 8.4 5.9 0.0 4.1 4 0 0 4 4 4 0 SHNi-TPR DUF4919 PF16266.5 EGG20921.1 - 0.063 13.2 1.3 0.45 10.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) PPR_2 PF13041.6 EGG20921.1 - 0.1 12.8 0.9 20 5.5 0.0 3.8 3 0 0 3 3 3 0 PPR repeat family SPO22 PF08631.10 EGG20921.1 - 0.15 11.5 9.0 9.1 5.7 0.2 4.0 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like SMBP PF16785.5 EGG20921.1 - 0.23 11.7 4.1 1.8 8.8 0.2 3.4 3 0 0 3 3 3 0 Small metal-binding protein Sel1 PF08238.12 EGG20921.1 - 1.7 9.4 4.6 79 4.1 0.1 4.4 4 0 0 4 4 3 0 Sel1 repeat NSF PF02071.20 EGG20921.1 - 2 9.5 11.0 32 5.9 0.2 4.6 4 0 0 4 4 3 0 Aromatic-di-Alanine (AdAR) repeat PPR PF01535.20 EGG20921.1 - 2.2 8.7 8.9 13 6.3 0.1 5.4 7 0 0 7 7 6 0 PPR repeat DKCLD PF08068.12 EGG20922.1 - 1.3e-33 114.8 0.1 2.9e-32 110.5 0.2 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain PUA PF01472.20 EGG20922.1 - 9e-23 80.0 0.9 1.8e-22 79.1 0.9 1.6 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 EGG20922.1 - 4.3e-21 74.8 0.5 8.8e-21 73.8 0.5 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EGG20922.1 - 2.8e-18 66.7 0.5 2.8e-18 66.7 0.5 4.0 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 EGG20922.1 - 0.0011 19.2 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain Menin PF05053.13 EGG20922.1 - 0.037 12.4 22.3 0.049 12.0 22.3 1.2 1 0 0 1 1 1 0 Menin CDC27 PF09507.10 EGG20922.1 - 0.13 11.7 54.8 0.17 11.2 54.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Snf7 PF03357.21 EGG20924.1 - 9.8e-42 142.5 30.4 1.2e-41 142.2 30.4 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 EGG20924.1 - 0.0034 17.3 9.2 0.0044 17.0 9.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway GCH_III PF05165.12 EGG20924.1 - 0.043 13.1 3.6 2 7.6 0.8 2.1 1 1 1 2 2 2 0 GTP cyclohydrolase III Hemagglutinin PF00509.18 EGG20924.1 - 1.4 7.2 7.8 0.054 11.9 2.2 1.5 2 0 0 2 2 2 0 Haemagglutinin RhoGAP PF00620.27 EGG20925.1 - 4.2e-05 23.4 0.4 0.00014 21.7 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain DUF2753 PF10952.8 EGG20925.1 - 0.055 13.6 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) MJ1316 PF04457.12 EGG20926.1 - 2.1e-13 50.8 3.4 4.5e-13 49.7 2.0 2.2 1 1 1 2 2 2 1 MJ1316 RNA cyclic group end recognition domain EFTUD2 PF16004.5 EGG20926.1 - 0.25 11.9 13.5 0.082 13.5 10.4 1.8 2 1 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus YABBY PF04690.13 EGG20926.1 - 0.85 10.2 3.9 1.5 9.4 3.9 1.5 1 0 0 1 1 1 0 YABBY protein Eaf7 PF07904.13 EGG20926.1 - 3 8.2 0.0 3 8.2 0.0 2.9 2 1 0 2 2 2 0 Chromatin modification-related protein EAF7 VMA21 PF09446.10 EGG20927.1 - 1.9e-15 56.7 6.7 2.7e-15 56.2 6.7 1.2 1 0 0 1 1 1 1 VMA21-like domain EVI2A PF05399.11 EGG20927.1 - 0.023 14.3 9.2 0.031 13.9 8.8 1.4 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Yip1 PF04893.17 EGG20927.1 - 0.026 14.2 0.4 0.036 13.8 0.4 1.1 1 0 0 1 1 1 0 Yip1 domain Tom5 PF10642.9 EGG20927.1 - 0.064 13.3 0.0 0.064 13.3 0.0 2.1 2 1 1 3 3 3 0 Mitochondrial import receptor subunit or translocase ORC6 PF05460.13 EGG20927.1 - 0.23 10.7 18.0 0.29 10.4 18.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Membralin PF09746.9 EGG20927.1 - 0.93 8.5 3.7 1.1 8.2 3.7 1.2 1 0 0 1 1 1 0 Tumour-associated protein GREB1 PF15782.5 EGG20927.1 - 1.4 5.9 14.1 1.6 5.8 14.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Orf78 PF06024.12 EGG20927.1 - 1.5 9.1 7.1 1.6e+02 2.7 7.0 2.5 1 1 0 1 1 1 0 Orf78 (ac78) DUF966 PF06136.13 EGG20927.1 - 2.5 7.7 16.9 3.1 7.4 16.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) ALMT PF11744.8 EGG20927.1 - 4.4 6.0 9.4 5.6 5.7 9.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter LMBR1 PF04791.16 EGG20927.1 - 4.5 6.1 8.7 5.3 5.8 8.7 1.2 1 1 0 1 1 1 0 LMBR1-like membrane protein SLC12 PF03522.15 EGG20927.1 - 4.6 6.2 11.3 5.4 5.9 11.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4407 PF14362.6 EGG20927.1 - 6 6.1 10.3 0.51 9.6 4.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PAP1 PF08601.10 EGG20927.1 - 7 6.3 20.1 8 6.1 20.1 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Dicty_REP PF05086.12 EGG20927.1 - 7.6 4.4 18.8 8.7 4.2 18.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF5521 PF17659.1 EGG20927.1 - 8.4 4.1 10.0 9.5 3.9 10.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) RasGEF PF00617.19 EGG20928.1 - 2.8e-51 174.2 0.6 2.8e-51 174.2 0.6 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGG20928.1 - 6.7e-16 58.4 4.1 6.7e-16 58.4 4.1 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif WH1 PF00568.23 EGG20928.1 - 0.00019 21.3 1.3 0.00044 20.2 0.2 2.2 2 0 0 2 2 2 1 WH1 domain VHS PF00790.19 EGG20928.1 - 0.29 11.0 4.2 1.2 9.0 0.1 3.2 3 0 0 3 3 3 0 VHS domain TPR_2 PF07719.17 EGG20930.1 - 1.4e-17 62.3 0.9 0.00037 20.4 0.1 5.7 6 1 1 7 7 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGG20930.1 - 1.8e-13 49.6 0.1 8.6e-05 22.2 0.2 4.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG20930.1 - 1.7e-12 47.0 5.5 0.0041 17.8 0.1 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG20930.1 - 1.4e-11 44.8 0.6 1.4e-05 25.6 0.0 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG20930.1 - 7.8e-10 38.2 3.5 0.0013 18.8 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG20930.1 - 4.2e-08 32.7 1.6 0.18 11.9 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG20930.1 - 6.9e-08 32.0 0.0 0.002 17.8 0.0 3.7 2 1 1 3 3 3 3 TPR repeat TPR_12 PF13424.6 EGG20930.1 - 7.1e-08 32.6 7.1 0.029 14.6 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGG20930.1 - 1.5e-06 28.2 0.1 9.7e-05 22.4 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG20930.1 - 6.3e-05 23.1 0.1 0.04 14.3 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG20930.1 - 0.00028 21.3 0.1 0.025 15.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGG20930.1 - 0.00059 19.6 5.8 0.057 13.3 0.2 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGG20930.1 - 0.0016 17.7 0.8 0.086 12.0 0.1 2.8 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG20930.1 - 0.0042 17.3 2.7 0.9 9.8 0.1 3.8 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EGG20930.1 - 0.008 15.6 0.0 1.5 8.1 0.0 2.6 2 0 0 2 2 2 1 MalT-like TPR region RPN7 PF10602.9 EGG20930.1 - 0.015 15.0 0.7 9.6 5.9 0.0 3.9 5 0 0 5 5 5 0 26S proteasome subunit RPN7 2H-phosphodiest PF08975.10 EGG20930.1 - 0.024 14.6 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) TPR_6 PF13174.6 EGG20930.1 - 0.96 10.2 4.2 59 4.6 0.4 4.4 4 1 0 4 4 3 0 Tetratricopeptide repeat AAA_5 PF07728.14 EGG20931.1 - 4e-114 376.7 0.0 7.9e-22 77.7 0.0 9.8 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EGG20931.1 - 3.2e-57 191.3 8.4 5.9e-23 81.1 0.1 6.8 7 0 0 7 7 5 4 Midasin AAA lid domain AAA_lid_5 PF17865.1 EGG20931.1 - 9e-31 106.1 0.0 4.8e-30 103.8 0.0 2.5 2 0 0 2 2 1 1 Midasin AAA lid domain AAA_3 PF07726.11 EGG20931.1 - 2.9e-26 91.9 0.0 4.4e-10 39.5 0.0 6.6 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EGG20931.1 - 6.6e-23 81.6 0.5 0.00024 21.5 0.0 8.3 7 1 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGG20931.1 - 9.8e-22 77.3 8.4 2.3e-06 27.3 0.3 6.5 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA_16 PF13191.6 EGG20931.1 - 1.2e-21 77.8 9.8 5.2e-06 27.0 0.8 8.1 6 2 0 6 6 6 4 AAA ATPase domain Dynein_heavy PF03028.15 EGG20931.1 - 3.4e-21 75.6 0.0 0.0021 18.1 0.0 8.8 8 0 0 8 8 8 4 Dynein heavy chain region D6 P-loop domain AAA_14 PF13173.6 EGG20931.1 - 2.5e-15 56.7 1.2 0.002 18.2 0.0 8.3 7 0 0 7 7 7 3 AAA domain AAA_22 PF13401.6 EGG20931.1 - 3.5e-13 50.0 14.1 0.006 16.9 0.3 9.4 9 1 0 9 9 8 3 AAA domain Sigma54_activat PF00158.26 EGG20931.1 - 6e-13 48.8 0.0 0.0034 17.1 0.0 5.4 5 0 0 5 5 5 3 Sigma-54 interaction domain AAA_6 PF12774.7 EGG20931.1 - 6.9e-13 48.3 0.0 0.075 12.0 0.0 7.8 8 1 0 8 8 8 2 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 EGG20931.1 - 6.7e-12 45.5 2.5 0.026 14.5 0.0 5.7 5 0 0 5 5 5 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGG20931.1 - 1.6e-10 41.3 0.8 0.88 9.7 0.0 6.2 6 0 0 6 6 5 3 AAA domain Zeta_toxin PF06414.12 EGG20931.1 - 1e-09 38.0 0.6 0.019 14.2 0.0 5.1 4 0 0 4 4 4 2 Zeta toxin Sigma54_activ_2 PF14532.6 EGG20931.1 - 2.2e-09 37.6 0.1 0.001 19.2 0.0 4.3 4 0 0 4 4 3 2 Sigma-54 interaction domain AAA_30 PF13604.6 EGG20931.1 - 1.6e-08 34.5 0.3 0.099 12.4 0.0 6.5 6 0 0 6 6 6 2 AAA domain NACHT PF05729.12 EGG20931.1 - 2.3e-08 34.1 1.4 0.37 10.7 0.0 5.9 5 0 0 5 5 5 2 NACHT domain AAA_18 PF13238.6 EGG20931.1 - 2.4e-08 34.6 9.8 2.1 8.9 0.0 7.5 6 0 0 6 6 4 4 AAA domain T2SSE PF00437.20 EGG20931.1 - 3.3e-08 32.9 8.0 0.019 14.0 0.0 6.1 6 0 0 6 6 6 2 Type II/IV secretion system protein RNA_helicase PF00910.22 EGG20931.1 - 1.2e-06 28.8 6.9 0.54 10.7 0.0 6.9 7 0 0 7 7 5 1 RNA helicase RuvB_N PF05496.12 EGG20931.1 - 1.3e-06 28.3 1.3 1.8 8.3 0.0 6.1 5 0 0 5 5 5 2 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 EGG20931.1 - 1.6e-06 28.1 5.7 0.61 10.0 0.4 5.9 5 0 0 5 5 5 2 RsgA GTPase IstB_IS21 PF01695.17 EGG20931.1 - 5.8e-06 26.2 0.7 1.6 8.4 0.0 4.7 5 0 0 5 5 4 1 IstB-like ATP binding protein AAA_29 PF13555.6 EGG20931.1 - 1.5e-05 24.6 3.0 3.4 7.5 0.0 5.5 5 0 0 5 5 5 1 P-loop containing region of AAA domain AAA_28 PF13521.6 EGG20931.1 - 2.7e-05 24.4 14.5 0.66 10.2 0.1 6.3 6 0 0 6 6 5 2 AAA domain cobW PF02492.19 EGG20931.1 - 6.3e-05 22.6 2.2 2.5 7.7 0.1 4.5 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EGG20931.1 - 7.2e-05 22.6 2.9 4 7.2 0.1 5.3 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EGG20931.1 - 0.00063 19.8 0.1 14 5.8 0.0 5.0 4 0 0 4 4 4 0 50S ribosome-binding GTPase AAA_25 PF13481.6 EGG20931.1 - 0.0014 18.2 0.6 12 5.4 0.0 5.3 6 0 0 6 6 5 0 AAA domain VWA_2 PF13519.6 EGG20931.1 - 0.002 18.7 3.1 0.01 16.5 0.0 3.8 4 0 0 4 4 2 1 von Willebrand factor type A domain Roc PF08477.13 EGG20931.1 - 0.003 17.8 5.4 35 4.7 0.1 6.5 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 EGG20931.1 - 0.0037 17.6 6.3 1.3 9.3 0.3 5.5 5 1 0 5 5 4 1 AAA domain ABC_tran PF00005.27 EGG20931.1 - 0.0037 17.8 0.3 0.0037 17.8 0.3 9.3 10 1 0 10 10 5 1 ABC transporter SRP54 PF00448.22 EGG20931.1 - 0.0066 16.1 3.0 7.6 6.1 0.1 5.3 6 0 0 6 6 6 0 SRP54-type protein, GTPase domain IPT PF01745.16 EGG20931.1 - 0.008 15.6 0.5 14 5.0 0.0 4.0 4 0 0 4 4 4 0 Isopentenyl transferase Viral_helicase1 PF01443.18 EGG20931.1 - 0.0098 15.7 0.0 6.5 6.4 0.0 4.4 4 0 0 4 4 3 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 EGG20931.1 - 0.02 14.6 0.3 19 4.9 0.0 4.6 4 0 0 4 4 3 0 Cytidylate kinase NTPase_1 PF03266.15 EGG20931.1 - 0.021 14.8 5.6 6.3 6.7 0.2 4.4 4 0 0 4 4 4 0 NTPase CPT PF07931.12 EGG20931.1 - 0.14 12.0 1.9 4.9 7.0 0.0 4.4 5 1 0 5 5 4 0 Chloramphenicol phosphotransferase-like protein UQ_con PF00179.26 EGG20932.1 - 1.9e-52 176.6 0.0 2.8e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGG20932.1 - 0.0011 18.6 0.1 0.0023 17.7 0.0 1.5 2 0 0 2 2 2 1 Prokaryotic E2 family B MucBP_2 PF17965.1 EGG20932.1 - 0.1 13.2 0.9 0.24 12.0 0.9 1.6 1 1 0 1 1 1 0 Mucin binding domain RWD PF05773.22 EGG20932.1 - 0.13 12.6 0.1 0.13 12.6 0.1 1.8 2 1 0 2 2 2 0 RWD domain DUF4160 PF13711.6 EGG20935.1 - 0.075 13.4 0.3 0.21 11.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) VPS13_C PF16909.5 EGG20936.1 - 3.4e-55 186.6 6.5 3.2e-54 183.4 1.5 5.8 6 0 0 6 6 6 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 EGG20936.1 - 2.2e-32 112.8 3.2 2.2e-32 112.8 3.2 7.0 6 2 1 7 7 7 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EGG20936.1 - 6.7e-30 103.6 0.3 6.7e-30 103.6 0.3 5.1 3 1 0 3 3 2 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 EGG20936.1 - 1.1e-29 103.6 3.6 1.1e-29 103.6 3.6 5.6 5 1 0 5 5 5 2 SHR-binding domain of vacuolar-sorting associated protein 13 HA2 PF04408.23 EGG20936.1 - 1.2e-21 77.1 0.0 1.2e-21 77.1 0.0 4.1 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGG20936.1 - 1.4e-16 60.6 0.0 5.5e-16 58.7 0.0 2.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGG20936.1 - 5.9e-16 58.8 0.0 4.1e-15 56.1 0.0 2.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ATG_C PF09333.11 EGG20936.1 - 6.1e-09 36.1 0.1 3.6e-08 33.6 0.1 2.4 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DEAD PF00270.29 EGG20936.1 - 4.9e-07 29.7 3.8 1.7e-06 27.9 0.1 3.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGG20936.1 - 0.0013 19.0 0.0 0.0049 17.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain bPH_3 PF14470.6 EGG20936.1 - 0.0069 16.7 0.1 0.062 13.7 0.1 2.8 1 0 0 1 1 1 1 Bacterial PH domain DUF3112 PF11309.8 EGG20936.1 - 3.8 6.9 5.9 2.7 7.4 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) RRM_1 PF00076.22 EGG20937.1 - 4.2e-12 45.7 0.4 9.3e-07 28.6 0.2 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IL13 PF03487.13 EGG20937.1 - 0.077 12.8 0.3 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Interleukin-13 DDE_Tnp_4 PF13359.6 EGG20938.1 - 4e-25 88.3 0.0 4.7e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGG20938.1 - 5.7e-05 22.9 0.0 0.00012 21.7 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain WSS_VP PF12175.8 EGG20938.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP DUF4834 PF16118.5 EGG20939.1 - 0.11 13.4 2.5 1.3 10.0 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF913 PF06025.12 EGG20939.1 - 0.49 9.3 5.6 2.8 6.8 5.3 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EGG20939.1 - 5.3 5.7 10.3 8.4 5.0 10.3 1.3 1 0 0 1 1 1 0 Presenilin PBP1_TM PF14812.6 EGG20939.1 - 8.2 6.9 16.5 18 5.8 16.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_25 PF01183.20 EGG20940.1 - 5.9e-05 23.3 2.1 8.4e-05 22.8 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 CBS PF00571.28 EGG20941.1 - 9.9e-15 54.7 3.0 6.7e-05 23.2 0.1 4.6 4 0 0 4 4 4 3 CBS domain HEPN_RES_NTD1 PF18870.1 EGG20941.1 - 0.078 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 PPI_Ypi1 PF07491.11 EGG20942.1 - 1.5e-22 79.2 7.6 1.5e-22 79.2 7.6 1.9 2 1 0 2 2 2 1 Protein phosphatase inhibitor Tir_receptor_C PF07489.11 EGG20942.1 - 0.19 11.7 4.3 0.22 11.5 4.3 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Ras PF00071.22 EGG20943.1 - 7.5e-50 168.7 1.1 7.5e-50 168.7 1.1 1.5 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGG20943.1 - 1.7e-23 83.1 0.1 3.2e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG20943.1 - 3.6e-08 33.1 1.2 4.5e-08 32.8 0.2 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG20943.1 - 3.2e-05 23.5 0.1 4.1e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Nic96 PF04097.14 EGG20946.1 - 2.7e-67 227.6 5.7 2.1e-66 224.7 3.0 2.6 2 1 0 2 2 2 1 Nup93/Nic96 COX14 PF14880.6 EGG20947.1 - 6.9e-07 29.0 0.4 6.9e-07 29.0 0.4 1.8 1 1 1 2 2 2 1 Cytochrome oxidase c assembly Peptidase_M20 PF01546.28 EGG20948.1 - 9.1e-35 120.2 0.0 1.3e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGG20948.1 - 1.5e-16 60.2 0.0 2.7e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGG20948.1 - 0.00052 19.8 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 EGG20948.1 - 0.0016 17.5 0.1 0.041 12.9 0.0 2.2 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Phosphoesterase PF04185.14 EGG20949.1 - 7.2e-88 295.2 1.8 1.1e-87 294.5 1.8 1.2 1 0 0 1 1 1 1 Phosphoesterase family Myticin-prepro PF10690.9 EGG20949.1 - 0.02 15.1 0.3 0.049 13.9 0.3 1.6 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel YL1 PF05764.13 EGG20950.1 - 0.79 9.8 13.4 0.86 9.7 13.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 EGG20950.1 - 0.99 7.6 14.9 1 7.6 14.9 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EGG20950.1 - 2.9 7.2 15.7 3 7.2 15.7 1.1 1 0 0 1 1 1 0 SDA1 AAA_18 PF13238.6 EGG20952.1 - 3.8e-27 95.4 0.2 5.8e-27 94.8 0.0 1.4 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 EGG20952.1 - 1e-09 38.9 0.3 4.2e-09 36.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EGG20952.1 - 1.9e-06 28.3 0.0 3.9e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGG20952.1 - 3.3e-06 27.4 0.5 9.1e-06 26.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG20952.1 - 1.1e-05 25.7 0.9 0.00027 21.1 0.9 2.6 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EGG20952.1 - 8.4e-05 22.7 0.3 0.00017 21.8 0.3 1.5 1 1 0 1 1 1 1 Shikimate kinase NTPase_1 PF03266.15 EGG20952.1 - 9.5e-05 22.4 0.0 0.00019 21.4 0.0 1.5 1 1 0 1 1 1 1 NTPase AAA_16 PF13191.6 EGG20952.1 - 0.00018 21.9 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ADK PF00406.22 EGG20952.1 - 0.0002 21.5 2.6 0.0018 18.4 0.0 2.7 1 1 1 2 2 2 1 Adenylate kinase RNA_helicase PF00910.22 EGG20952.1 - 0.00022 21.5 0.2 0.00052 20.4 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA_24 PF13479.6 EGG20952.1 - 0.00037 20.3 0.4 0.0038 17.0 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 EGG20952.1 - 0.0004 20.7 0.1 0.0012 19.2 0.0 1.8 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 EGG20952.1 - 0.00066 19.2 0.4 0.0018 17.8 0.0 1.8 1 1 1 2 2 2 1 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 EGG20952.1 - 0.00068 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 EGG20952.1 - 0.0016 18.2 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EGG20952.1 - 0.0021 18.0 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.14 EGG20952.1 - 0.0022 18.0 0.0 0.0045 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 EGG20952.1 - 0.0023 17.3 0.3 0.0045 16.4 0.0 1.6 2 0 0 2 2 2 1 KaiC ResIII PF04851.15 EGG20952.1 - 0.0025 17.8 0.5 0.0086 16.1 0.5 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit dNK PF01712.19 EGG20952.1 - 0.0028 17.6 6.7 0.36 10.7 0.1 2.1 1 1 0 2 2 2 2 Deoxynucleoside kinase TsaE PF02367.17 EGG20952.1 - 0.0036 17.3 0.3 0.009 16.0 0.0 1.8 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EGG20952.1 - 0.0038 17.6 0.8 0.0061 16.9 0.8 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 EGG20952.1 - 0.0044 17.2 0.1 0.0081 16.3 0.1 1.8 1 1 0 1 1 1 1 Cytidylate kinase-like family Hydin_ADK PF17213.3 EGG20952.1 - 0.005 17.2 0.8 0.013 15.8 0.8 1.8 1 1 0 1 1 1 1 Hydin Adenylate kinase-like domain Rad17 PF03215.15 EGG20952.1 - 0.0056 16.6 0.2 0.059 13.3 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain HECA PF15353.6 EGG20952.1 - 0.007 16.6 0.1 0.013 15.7 0.1 1.4 1 0 0 1 1 1 1 Headcase protein family homologue T2SSE PF00437.20 EGG20952.1 - 0.0097 15.0 0.2 0.0097 15.0 0.2 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Parvo_NS1 PF01057.17 EGG20952.1 - 0.01 15.0 0.0 0.032 13.3 0.0 1.8 2 1 0 2 2 2 0 Parvovirus non-structural protein NS1 TIP49 PF06068.13 EGG20952.1 - 0.01 15.1 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Thymidylate_kin PF02223.17 EGG20952.1 - 0.015 14.9 2.0 2.2 7.9 0.1 2.1 2 0 0 2 2 2 0 Thymidylate kinase Mg_chelatase PF01078.21 EGG20952.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 EGG20952.1 - 0.021 14.8 0.0 0.029 14.3 0.0 1.4 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 EGG20952.1 - 0.021 14.6 0.5 0.044 13.5 0.3 1.5 1 1 1 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EGG20952.1 - 0.021 14.6 0.0 0.071 12.8 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_29 PF13555.6 EGG20952.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 EGG20952.1 - 0.022 13.8 0.3 0.25 10.4 0.0 2.3 2 1 0 2 2 2 0 MCM P-loop domain Sigma54_activat PF00158.26 EGG20952.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 EGG20952.1 - 0.027 14.5 1.2 0.072 13.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain CoaE PF01121.20 EGG20952.1 - 0.029 14.0 1.1 0.24 11.1 0.1 2.3 2 2 0 2 2 2 0 Dephospho-CoA kinase MobB PF03205.14 EGG20952.1 - 0.03 14.2 0.2 0.079 12.9 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 EGG20952.1 - 0.031 13.8 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 EGG20952.1 - 0.031 14.1 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EGG20952.1 - 0.04 13.2 0.1 0.095 12.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EGG20952.1 - 0.05 12.9 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family UvrD-helicase PF00580.21 EGG20952.1 - 0.06 12.9 4.7 0.32 10.4 0.1 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain cobW PF02492.19 EGG20952.1 - 0.064 12.8 0.6 0.14 11.8 0.6 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 EGG20952.1 - 0.072 12.6 0.5 0.1 12.2 0.0 1.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Mur_ligase_M PF08245.12 EGG20952.1 - 0.077 13.0 0.1 4.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Mur ligase middle domain AAA_23 PF13476.6 EGG20952.1 - 0.082 13.4 6.6 0.19 12.2 6.6 1.6 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 EGG20952.1 - 0.083 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EGG20952.1 - 0.1 13.1 2.0 0.26 11.8 2.0 2.0 1 1 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 EGG20952.1 - 0.1 12.5 0.2 0.27 11.1 0.0 1.8 2 1 0 2 2 1 0 Adenylylsulphate kinase Viral_helicase1 PF01443.18 EGG20952.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EGG20952.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Alk_phosphatase PF00245.20 EGG20953.1 - 7e-87 292.1 5.7 1.6e-86 290.8 5.7 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EGG20953.1 - 9.5e-06 25.2 0.2 2e-05 24.1 0.1 1.5 2 0 0 2 2 2 1 Metalloenzyme superfamily PalH PF08733.10 EGG20953.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 PalH/RIM21 RabGAP-TBC PF00566.18 EGG20954.1 - 3.2e-45 154.4 0.1 3.2e-45 154.4 0.1 2.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 EGG20954.1 - 6.8e-41 138.8 0.0 1.4e-10 41.6 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG20954.1 - 2.9e-27 94.7 1.2 2.4e-06 28.0 0.1 7.5 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 EGG20954.1 - 3.3e-25 87.4 2.3 0.0047 17.3 0.0 8.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EGG20954.1 - 5.9e-21 74.3 0.0 0.00012 22.3 0.0 5.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG20954.1 - 2.9e-18 64.0 0.1 0.22 12.2 0.0 9.2 9 0 0 9 9 9 5 Ankyrin repeat LANC_like PF05147.13 EGG20954.1 - 0.042 12.4 2.2 0.39 9.2 0.0 2.3 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein PC4 PF02229.16 EGG20956.1 - 3e-12 46.0 0.0 4.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) PBP1_TM PF14812.6 EGG20956.1 - 0.13 12.6 8.2 0.24 11.8 8.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 EGG20956.1 - 2.2 7.5 8.4 3.1 7.1 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 EGG20956.1 - 9.3 5.9 7.8 14 5.3 7.8 1.3 1 0 0 1 1 1 0 FAM176 family zf-C3HC4_3 PF13920.6 EGG20957.1 - 1.3e-11 44.2 11.1 2.1e-11 43.5 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG20957.1 - 3e-06 27.0 10.7 6e-06 26.0 10.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGG20957.1 - 0.0037 17.6 12.4 0.0077 16.5 12.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGG20957.1 - 0.01 15.8 12.7 0.019 14.9 12.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EGG20957.1 - 0.42 10.5 11.3 1.2 9.1 11.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 EGG20957.1 - 0.43 11.1 6.6 1.4 9.4 6.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 EGG20957.1 - 1 9.2 12.3 2.4 8.1 12.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Macoilin PF09726.9 EGG20957.1 - 2 6.9 51.9 2.7 6.4 51.9 1.1 1 0 0 1 1 1 0 Macoilin family zf-P11 PF03854.14 EGG20957.1 - 3.4 7.4 7.6 6.6 6.5 7.6 1.5 1 0 0 1 1 1 0 P-11 zinc finger CENP-F_leu_zip PF10473.9 EGG20957.1 - 5.3 7.1 54.6 0.027 14.5 22.6 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.8 EGG20957.1 - 6.3 6.4 28.7 1 9.0 10.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) zf-C3HC4_4 PF15227.6 EGG20957.1 - 7.1 6.9 10.3 7.6 6.8 6.0 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING AAA_25 PF13481.6 EGG20958.1 - 1.3e-08 34.7 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 EGG20958.1 - 1.7e-07 31.5 0.0 7.7e-07 29.5 0.0 2.2 1 0 0 1 1 1 1 Toprim-like ATPase PF06745.13 EGG20958.1 - 3.3e-05 23.4 0.0 5.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.15 EGG20958.1 - 7.5e-05 22.2 0.0 0.00016 21.1 0.0 1.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Toprim_4 PF13662.6 EGG20958.1 - 0.00028 21.3 0.0 0.00091 19.7 0.0 1.9 1 0 0 1 1 1 1 Toprim domain AAA_22 PF13401.6 EGG20958.1 - 0.00046 20.5 0.1 0.0016 18.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGG20958.1 - 0.0021 17.8 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 EGG20958.1 - 0.0056 17.1 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EGG20958.1 - 0.06 13.3 0.3 0.16 11.9 0.3 1.8 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 EGG20958.1 - 0.085 12.9 0.6 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Toprim_3 PF13362.6 EGG20958.1 - 0.098 13.0 0.0 0.33 11.3 0.0 2.0 1 0 0 1 1 1 0 Toprim domain AAA_lid_7 PF17867.1 EGG20958.1 - 0.21 11.8 0.6 3.6 7.8 0.0 2.8 3 0 0 3 3 3 0 Midasin AAA lid domain MRI PF15325.6 EGG20958.1 - 0.22 12.6 3.6 0.3 12.2 1.9 2.2 2 0 0 2 2 1 0 Modulator of retrovirus infection Neur_chan_memb PF02932.16 EGG20959.1 - 0.61 10.1 4.5 1.1 9.3 4.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Y_phosphatase PF00102.27 EGG20960.1 - 2.6e-76 256.3 1.9 3.4e-76 255.9 1.9 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGG20960.1 - 3.7e-07 30.0 0.0 9.4e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGG20960.1 - 0.0002 21.5 0.1 0.0014 18.8 0.0 2.4 2 1 1 3 3 3 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGG20960.1 - 0.00033 20.7 0.0 0.00046 20.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Blt1 PF12754.7 EGG20961.1 - 0.09 13.1 0.7 0.15 12.3 0.7 1.4 1 1 0 1 1 1 0 Blt1 N-terminal domain PSS PF03034.15 EGG20962.1 - 3.2e-111 371.5 11.8 4.6e-111 371.0 11.8 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase VPS13 PF16908.5 EGG20963.1 - 1.2e-64 218.4 24.5 8.2e-64 215.6 3.2 5.7 6 0 0 6 6 6 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EGG20963.1 - 1.2e-58 197.9 16.4 1.6e-55 187.6 0.4 5.0 4 0 0 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 EGG20963.1 - 1.1e-51 175.5 27.2 1.3e-49 168.8 4.3 6.5 7 1 0 7 7 7 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 EGG20963.1 - 6.2e-51 173.3 9.6 1.4e-47 162.3 0.2 3.4 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 EGG20963.1 - 5.6e-39 132.9 3.4 2.6e-38 130.7 1.1 3.3 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EGG20963.1 - 3.3e-11 43.4 0.0 1.1e-09 38.6 0.1 2.7 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Pkinase PF00069.25 EGG20965.1 - 0.0022 17.4 0.0 0.0056 16.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain rve PF00665.26 EGG20965.1 - 0.049 13.8 0.1 1.8 8.8 0.0 2.5 3 0 0 3 3 3 0 Integrase core domain FTA2 PF13095.6 EGG20965.1 - 0.056 13.1 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Babuvirus_MP PF07234.11 EGG20966.1 - 6.4 7.0 6.1 0.9 9.7 2.3 1.6 2 0 0 2 2 2 0 Movement and RNA silencing protein Adeno_E3B PF03376.14 EGG20967.1 - 0.68 10.2 5.0 1.2 9.4 5.0 1.4 1 0 0 1 1 1 0 Adenovirus E3B protein Wzy_C PF04932.15 EGG20967.1 - 3.4 7.3 6.3 4.3 7.0 6.2 1.3 1 1 0 1 1 1 0 O-Antigen ligase O-antigen_lig PF13425.6 EGG20968.1 - 0.0027 16.6 3.8 0.004 16.0 3.8 1.3 1 0 0 1 1 1 1 O-antigen ligase like membrane protein Erf4 PF10256.9 EGG20968.1 - 0.0037 17.4 0.3 0.016 15.3 0.2 2.1 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family AA_permease PF00324.21 EGG20968.1 - 0.0081 14.8 0.6 0.011 14.4 0.6 1.1 1 0 0 1 1 1 1 Amino acid permease Wzy_C PF04932.15 EGG20968.1 - 0.019 14.6 3.9 0.033 13.8 3.9 1.5 1 1 0 1 1 1 0 O-Antigen ligase S_4TM PF18159.1 EGG20968.1 - 0.034 13.5 3.3 0.027 13.8 1.0 1.8 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain TNFR_16_TM PF18422.1 EGG20968.1 - 0.034 14.1 0.8 0.034 14.1 0.8 2.1 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain TMCCDC2 PF15844.5 EGG20968.1 - 0.042 13.8 1.5 0.076 12.9 1.5 1.4 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 Ferlin_C PF16165.5 EGG20968.1 - 0.32 10.9 5.7 5.3 7.0 0.6 2.5 2 0 0 2 2 2 0 Ferlin C-terminus Xin PF08043.12 EGG20968.1 - 3 7.6 4.0 1.4 8.7 1.2 2.1 2 0 0 2 2 2 0 Xin repeat ASFV_J13L PF05568.11 EGG20968.1 - 8 6.2 10.4 0.54 10.0 1.2 2.8 1 1 2 3 3 3 0 African swine fever virus J13L protein DUF2207 PF09972.9 EGG20969.1 - 0.0089 14.8 0.3 0.012 14.5 0.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) YhhN PF07947.14 EGG20969.1 - 0.026 14.1 1.6 0.039 13.6 1.6 1.2 1 0 0 1 1 1 0 YhhN family DUF4131 PF13567.6 EGG20969.1 - 0.043 13.5 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RseC_MucC PF04246.12 EGG20969.1 - 0.12 12.4 1.7 0.19 11.7 1.7 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF4191 PF13829.6 EGG20969.1 - 0.14 11.5 0.8 0.19 11.0 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF3040 PF11239.8 EGG20969.1 - 0.82 10.0 4.0 1.4 9.3 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) SLAC1 PF03595.17 EGG20969.1 - 2.9 7.1 8.0 5.9 6.1 8.0 1.4 1 1 0 1 1 1 0 Voltage-dependent anion channel EphA2_TM PF14575.6 EGG20969.1 - 4.1 8.3 5.3 1.3 9.9 0.2 2.4 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pyr_redox_2 PF07992.14 EGG20970.1 - 6.2e-69 232.5 2.3 8e-69 232.1 2.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGG20970.1 - 1.7e-33 115.2 0.4 5.5e-33 113.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGG20970.1 - 1.5e-21 76.8 4.7 5.9e-20 71.6 0.3 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG20970.1 - 2.2e-17 63.3 2.1 1.6e-16 60.5 2.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGG20970.1 - 1e-05 25.1 1.3 5.1e-05 22.8 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG20970.1 - 9.3e-05 21.3 2.3 0.36 9.5 0.0 3.2 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.24 EGG20970.1 - 0.00029 20.5 3.6 0.035 13.7 0.3 3.3 4 1 0 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.22 EGG20970.1 - 0.001 18.2 6.5 0.0026 16.9 2.8 2.7 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EGG20970.1 - 0.0041 16.4 2.0 1.5 8.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 EGG20970.1 - 0.0083 15.3 3.7 0.074 12.1 0.4 2.5 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EGG20970.1 - 0.016 14.5 1.1 1.3 8.3 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EGG20970.1 - 0.024 13.9 0.8 0.73 9.1 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EGG20970.1 - 0.047 12.9 0.2 0.16 11.2 0.1 1.9 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.6 EGG20970.1 - 0.063 12.4 0.0 0.2 10.7 0.0 1.7 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGG20970.1 - 0.12 12.7 5.7 0.076 13.3 2.5 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.6 EGG20970.1 - 0.13 12.8 0.3 0.41 11.2 0.1 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Inj_translocase PF16928.5 EGG20970.1 - 2.8 7.3 5.1 5.5 6.4 5.1 1.4 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Pkinase PF00069.25 EGG20971.1 - 4.6e-77 258.9 0.0 5.2e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG20971.1 - 4.7e-34 117.9 0.0 5.9e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG20971.1 - 8.3e-08 31.6 0.0 2e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGG20971.1 - 0.00082 19.4 0.0 0.019 14.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG20971.1 - 0.0037 16.6 0.2 0.021 14.1 0.1 2.1 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EGG20971.1 - 0.0046 16.1 0.0 0.0073 15.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EGG20971.1 - 0.0083 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGG20971.1 - 0.049 13.2 0.3 0.35 10.5 0.1 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TIP41 PF04176.13 EGG20972.1 - 9.2e-63 210.8 0.4 1.3e-62 210.3 0.4 1.2 1 0 0 1 1 1 1 TIP41-like family ACT PF01842.25 EGG20972.1 - 0.085 12.7 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 ACT domain SBDS_C PF09377.10 EGG20973.1 - 6.9e-34 116.3 2.7 1.8e-33 115.0 0.5 2.0 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 EGG20973.1 - 2.2e-31 107.8 1.4 4.3e-31 106.8 1.4 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Aminotran_5 PF00266.19 EGG20974.1 - 2.5e-32 112.2 0.0 3.8e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.17 EGG20974.1 - 7.2e-28 97.2 0.0 1.9e-27 95.9 0.0 1.7 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EGG20974.1 - 1.9e-20 72.9 0.0 3.9e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain CWC25 PF12542.8 EGG20974.1 - 0.095 13.6 0.2 0.095 13.6 0.2 2.8 3 0 0 3 3 3 0 Pre-mRNA splicing factor DUF2681 PF10883.8 EGG20974.1 - 0.91 10.0 8.5 15 6.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ESM4 PF15952.5 EGG20974.1 - 5.9 7.3 13.9 2.1 8.8 5.3 2.4 2 0 0 2 2 2 0 Enhancer of split M4 family Mcl1_mid PF12341.8 EGG20975.1 - 1.1e-71 241.7 2.0 6e-71 239.2 0.1 2.3 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EGG20975.1 - 1.6e-21 76.2 8.2 5.6e-08 33.3 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG20975.1 - 3.7e-13 49.6 0.2 0.018 15.3 0.0 6.5 5 1 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG20975.1 - 0.00022 20.3 0.1 0.11 11.5 0.0 2.9 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BUD22 PF09073.10 EGG20975.1 - 10 5.4 37.1 9.4 5.4 27.0 2.2 2 0 0 2 2 2 0 BUD22 Ank_3 PF13606.6 EGG20976.1 - 0.0091 16.4 18.6 25 5.9 0.0 11.6 16 0 0 16 16 16 1 Ankyrin repeat Se-cys_synth_N PF12390.8 EGG20976.1 - 0.13 12.6 0.2 75 3.7 0.0 3.3 3 0 0 3 3 3 0 Selenocysteine synthase N terminal Lipoprotein_10 PF03202.13 EGG20976.1 - 0.34 11.4 26.9 0.6 10.6 0.2 6.4 6 0 0 6 6 6 0 Putative mycoplasma lipoprotein, C-terminal region S_100 PF01023.19 EGG20976.1 - 0.93 9.2 4.9 54 3.6 0.1 3.9 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain EFP_N PF08207.12 EGG20976.1 - 4.8 7.3 5.0 53 4.0 0.1 3.1 3 0 0 3 3 3 0 Elongation factor P (EF-P) KOW-like domain JAB PF01398.21 EGG20977.1 - 5.5e-35 119.9 1.5 2.9e-34 117.6 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGG20977.1 - 9.1e-09 35.7 1.4 1.9e-08 34.7 1.4 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EGG20977.1 - 2.3e-08 33.8 0.0 1.1e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EGG20977.1 - 0.084 12.9 5.5 3.5 7.6 5.4 2.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) Clr2 PF10383.9 EGG20977.1 - 0.17 12.7 1.2 0.74 10.6 0.3 2.3 2 1 0 2 2 2 0 Transcription-silencing protein Clr2 Ank_2 PF12796.7 EGG20978.1 - 7e-13 49.0 0.1 1.4e-07 31.9 0.1 4.5 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG20978.1 - 2.6e-08 34.3 1.0 0.025 15.2 0.0 6.0 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG20978.1 - 4.4e-06 26.9 1.8 3.7 8.0 0.0 6.3 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG20978.1 - 1.8e-05 24.7 7.0 4.6 8.1 0.0 7.0 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 EGG20978.1 - 0.021 15.3 2.2 1.4 9.5 0.1 4.5 5 0 0 5 5 5 0 Ankyrin repeat CLU PF13236.6 EGG20979.1 - 7.5e-85 284.2 0.0 2.4e-84 282.6 0.0 2.0 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGG20979.1 - 1.9e-44 151.8 0.5 1.9e-44 151.8 0.5 3.7 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EGG20979.1 - 1.4e-24 86.1 2.8 9.5e-11 41.8 0.3 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGG20979.1 - 4e-21 74.2 1.6 1.1e-07 31.5 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat CLU_N PF15044.6 EGG20979.1 - 5.3e-14 52.3 0.1 2.4e-13 50.3 0.1 2.2 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_2 PF07719.17 EGG20979.1 - 3.8e-07 29.7 9.6 0.061 13.5 0.8 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG20979.1 - 2.3e-06 27.2 8.9 0.093 12.6 1.4 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG20979.1 - 0.00082 19.2 4.1 9.6 6.5 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat Rad60-SLD PF11976.8 EGG20979.1 - 0.0027 17.5 1.0 0.07 13.0 0.2 3.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TPR_8 PF13181.6 EGG20979.1 - 0.0065 16.6 6.4 3 8.3 0.7 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG20979.1 - 0.014 16.0 0.1 4.3 8.1 0.0 3.7 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1281 PF06924.11 EGG20979.1 - 0.037 13.6 0.2 0.091 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) TPR_14 PF13428.6 EGG20979.1 - 0.17 12.8 0.5 32 5.7 0.1 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat NIF PF03031.18 EGG20980.1 - 9.6e-26 90.4 1.7 9.6e-26 90.4 1.7 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EGG20980.1 - 7.3e-08 32.7 1.5 1.2e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGG20980.1 - 0.00013 21.8 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Biotin_lipoyl PF00364.22 EGG20980.1 - 0.0063 16.3 0.0 0.059 13.2 0.0 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Chordopox_RPO7 PF05864.12 EGG20980.1 - 0.049 13.9 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Cript PF10235.9 EGG20980.1 - 0.07 13.7 0.4 0.35 11.5 0.4 2.2 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT BORCS7 PF16088.5 EGG20981.1 - 8.5e-25 87.0 0.8 1.1e-24 86.6 0.8 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 BLOC1_2 PF10046.9 EGG20981.1 - 0.021 15.1 0.6 0.033 14.5 0.6 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HpaB_N PF11794.8 EGG20981.1 - 0.091 12.4 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Antigen_C PF16364.5 EGG20981.1 - 0.13 12.7 0.4 0.28 11.6 0.1 1.6 2 0 0 2 2 2 0 Cell surface antigen C-terminus DnaJ PF00226.31 EGG20982.1 - 6.6e-19 67.8 4.2 6.6e-19 67.8 4.2 1.8 2 0 0 2 2 2 1 DnaJ domain zf-CSL PF05207.13 EGG20982.1 - 2.4e-05 24.0 0.3 4.4e-05 23.1 0.3 1.5 1 0 0 1 1 1 1 CSL zinc finger ComP_DUS PF16732.5 EGG20982.1 - 0.13 13.2 0.9 0.27 12.1 0.9 1.6 1 0 0 1 1 1 0 Type IV minor pilin ComP, DNA uptake sequence receptor LRR_6 PF13516.6 EGG20983.1 - 1.1e-11 43.8 30.9 0.0065 16.4 0.1 8.8 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 EGG20983.1 - 0.0038 17.6 1.7 0.0038 17.6 1.7 6.5 5 3 1 6 6 6 3 Leucine Rich repeats (2 copies) ARID PF01388.21 EGG20983.1 - 0.1 13.3 0.3 0.62 10.8 0.1 2.2 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain Peptidase_U32_C PF16325.5 EGG20984.1 - 0.11 12.8 1.2 0.21 11.9 1.2 1.5 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain DUF3677 PF12432.8 EGG20985.1 - 0.0002 21.6 2.1 0.00032 21.0 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3677) TatD_DNase PF01026.21 EGG20986.1 - 8.7e-60 202.2 0.0 1.1e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 EGG20986.1 - 0.026 14.3 0.0 0.089 12.6 0.0 2.0 2 1 0 2 2 2 0 Amidohydrolase COMM_domain PF07258.14 EGG20987.1 - 4.1e-10 39.6 0.3 3.1e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 COMM domain eIF-1a PF01176.19 EGG20988.1 - 1.6e-18 66.2 0.0 3.6e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 SRP_TPR_like PF17004.5 EGG20988.1 - 1.5e-17 63.7 23.3 2.7e-17 62.9 5.0 4.6 2 2 2 4 4 4 2 Putative TPR-like repeat ANAPC3 PF12895.7 EGG20988.1 - 1.1e-14 54.4 26.6 0.0003 21.0 1.2 7.8 3 2 5 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGG20988.1 - 3.1e-14 53.2 17.2 0.0088 16.5 0.0 9.3 6 2 5 11 11 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG20988.1 - 5.6e-13 47.9 21.6 0.022 14.9 0.1 10.4 10 1 1 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGG20988.1 - 2.6e-11 42.8 29.6 0.005 16.6 0.2 9.0 10 0 0 10 10 9 4 Tetratricopeptide repeat SRP72 PF08492.12 EGG20988.1 - 7.5e-10 39.1 7.1 7.5e-10 39.1 7.1 3.2 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_14 PF13428.6 EGG20988.1 - 1.5e-09 37.9 0.6 8 7.6 0.0 8.2 7 2 2 9 9 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG20988.1 - 3.1e-07 29.9 7.3 0.7 10.1 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG20988.1 - 1.7e-06 28.3 16.7 0.67 10.7 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG20988.1 - 2.7e-06 27.9 2.0 3.8 8.2 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG20988.1 - 1.4e-05 25.3 15.4 2.4 8.5 0.1 8.3 7 3 1 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGG20988.1 - 0.00038 19.9 3.1 0.0088 15.4 3.2 3.0 2 1 1 3 3 3 1 MalT-like TPR region TPR_8 PF13181.6 EGG20988.1 - 0.00055 19.9 34.8 0.4 11.0 0.6 9.0 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGG20988.1 - 0.0012 18.9 0.0 8.3 6.6 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SR-25 PF10500.9 EGG20988.1 - 0.0081 15.8 12.8 0.0081 15.8 12.8 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein PG_binding_2 PF08823.11 EGG20988.1 - 0.036 14.4 0.6 15 6.0 0.2 3.2 2 0 0 2 2 2 0 Putative peptidoglycan binding domain FSA_C PF10479.9 EGG20988.1 - 0.12 10.5 8.4 0.21 9.7 8.4 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Alkyl_sulf_dimr PF14863.6 EGG20988.1 - 0.37 11.2 0.1 0.37 11.2 0.1 4.3 4 2 0 4 4 4 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 EGG20988.1 - 0.39 10.8 5.1 58 3.9 0.1 4.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Ndc1_Nup PF09531.10 EGG20988.1 - 0.5 9.0 9.6 0.069 11.8 5.2 1.7 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup TPR_11 PF13414.6 EGG20988.1 - 3.7 7.3 24.3 5.9 6.7 0.2 6.2 6 0 0 6 6 6 0 TPR repeat TPR_17 PF13431.6 EGG20988.1 - 4.9 7.8 9.9 47 4.7 0.0 5.9 8 0 0 8 8 5 0 Tetratricopeptide repeat A_thal_3526 PF09713.10 EGG20989.1 - 2.6e-20 72.4 0.5 7e-20 71.0 0.5 1.7 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) TMEM151 PF14857.6 EGG20989.1 - 0.15 10.9 2.0 0.82 8.5 0.1 2.1 2 0 0 2 2 2 0 TMEM151 family RNase_P_Rpp14 PF01900.19 EGG20990.1 - 3.3e-10 40.1 0.0 5.2e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Rpp14/Pop5 family Cwf_Cwc_15 PF04889.12 EGG20990.1 - 0.0057 16.4 18.0 0.0078 16.0 18.0 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 EGG20990.1 - 0.0091 16.3 9.7 0.013 15.8 9.7 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RD3 PF14473.6 EGG20990.1 - 0.0099 15.7 1.9 3.1 7.7 0.8 2.3 2 0 0 2 2 2 2 RD3 protein BUD22 PF09073.10 EGG20990.1 - 0.59 9.4 12.8 0.79 9.0 12.8 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 EGG20990.1 - 1.8 7.8 17.6 2.7 7.2 17.6 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 EGG20990.1 - 2.2 7.8 14.4 4.2 6.9 14.4 1.4 1 0 0 1 1 1 0 PPP4R2 CNDH2_M PF16869.5 EGG20990.1 - 3.9 8.1 11.5 6 7.6 11.5 1.2 1 0 0 1 1 1 0 PF16858 Ricin_B_lectin PF00652.22 EGG20991.1 - 2.7e-14 53.5 0.0 3.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EGG20991.1 - 8.9e-07 29.6 0.0 1.8e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EGG20992.1 - 3.9e-16 59.5 0.6 3.9e-16 59.5 0.6 2.0 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EGG20992.1 - 4.7e-05 24.0 0.2 0.014 16.1 0.1 3.3 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like DUF3472 PF11958.8 EGG20992.1 - 0.00049 20.6 6.4 0.0014 19.2 6.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3472) Ricin_B_lectin PF00652.22 EGG20993.1 - 3.4e-15 56.4 5.7 3.4e-15 56.4 5.7 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EGG20993.1 - 1.7e-10 41.5 10.1 2.3e-06 28.2 0.1 3.5 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like DUF3472 PF11958.8 EGG20993.1 - 2.5e-07 31.3 4.0 1.6e-06 28.7 4.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3472) CDtoxinA PF03498.14 EGG20993.1 - 0.2 11.2 3.1 2.8 7.5 0.2 2.6 1 1 0 2 2 2 0 Cytolethal distending toxin A/C domain Mito_carr PF00153.27 EGG20994.1 - 5e-61 202.6 5.4 1.2e-19 70.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NMO PF03060.15 EGG20995.1 - 2.5e-61 207.9 0.0 3.4e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGG20995.1 - 7.4e-09 35.1 0.1 0.00072 18.7 0.0 2.3 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 EGG20995.1 - 5.9e-05 22.4 1.5 0.00014 21.2 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EGG20995.1 - 0.00038 19.6 0.0 0.00085 18.4 0.0 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Aminotran_1_2 PF00155.21 EGG20996.1 - 2.3e-70 237.6 0.0 2.6e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGG20996.1 - 5.3e-08 32.2 0.0 8.2e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGG20996.1 - 6e-06 25.0 0.0 9.9e-06 24.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGG20996.1 - 2e-05 24.1 0.0 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EGG20996.1 - 5.8e-05 22.5 0.0 8.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.7 EGG20996.1 - 0.0052 15.6 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Glyco_hydro_20 PF00728.22 EGG20996.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain CoA_transf_3 PF02515.17 EGG20997.1 - 2.6e-114 382.2 0.0 1.4e-112 376.5 0.0 2.0 1 1 0 1 1 1 1 CoA-transferase family III PAP2 PF01569.21 EGG20998.1 - 3.3e-17 62.5 2.5 3.3e-17 62.5 2.5 2.0 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EGG20998.1 - 0.044 13.9 1.2 1.3 9.2 0.2 2.5 1 1 0 2 2 2 0 Divergent PAP2 family Polysacc_synt_C PF14667.6 EGG20998.1 - 4.9 7.2 12.4 33 4.5 12.5 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Dicty_CTDC PF00526.18 EGG21000.1 - 7.5e-67 220.8 382.1 3.5e-07 30.0 14.0 23.8 21 4 2 23 23 23 18 Dictyostelium (slime mold) repeat Amidinotransf PF02274.17 EGG21001.1 - 3.6e-59 200.6 1.3 4.1e-52 177.4 0.0 3.3 3 1 0 3 3 3 3 Amidinotransferase PAD_porph PF04371.15 EGG21001.1 - 0.042 13.1 0.2 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Porphyromonas-type peptidyl-arginine deiminase Glyco_transf_4 PF13439.6 EGG21001.1 - 0.06 13.3 0.1 0.46 10.5 0.1 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Methyltransf_16 PF10294.9 EGG21002.1 - 2.1e-23 82.9 0.1 3.6e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EGG21002.1 - 0.00011 22.9 0.3 0.0018 19.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGG21002.1 - 0.00073 19.0 0.1 0.0012 18.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EGG21002.1 - 0.0064 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGG21002.1 - 0.048 13.2 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MqsR_toxin PF15723.5 EGG21002.1 - 0.059 13.7 0.1 1.1 9.6 0.0 2.8 3 0 0 3 3 3 0 Motility quorum-sensing regulator, toxin of MqsA Methyltransf_25 PF13649.6 EGG21002.1 - 0.11 13.2 0.1 0.35 11.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DnaJ PF00226.31 EGG21003.1 - 1.7e-17 63.3 0.7 3.2e-17 62.4 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain zf-MYND PF01753.18 EGG21003.1 - 5.7e-11 42.3 13.9 9e-11 41.7 13.9 1.3 1 0 0 1 1 1 1 MYND finger DUF4568 PF15132.6 EGG21003.1 - 0.059 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) DUF4834 PF16118.5 EGG21003.1 - 5.2 8.1 0.0 5.2 8.1 0.0 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 EGG21004.1 - 3.2e-50 172.4 20.1 4e-32 112.7 11.0 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit NPL PF17800.1 EGG21004.1 - 0.016 15.8 2.7 0.57 10.8 0.3 2.3 2 0 0 2 2 2 0 Nucleoplasmin-like domain DUF4551 PF15087.6 EGG21004.1 - 3 6.5 10.4 4.2 6.1 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Translin PF01997.16 EGG21005.1 - 1.9e-51 175.0 3.3 2.7e-51 174.5 3.3 1.2 1 0 0 1 1 1 1 Translin family Mucin PF01456.17 EGG21005.1 - 0.38 10.7 5.7 0.59 10.1 5.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein OATP PF03137.20 EGG21007.1 - 0.025 12.9 0.1 0.11 10.7 0.0 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CYSTM PF12734.7 EGG21007.1 - 0.033 14.5 0.8 1.7 9.0 0.0 3.0 3 0 0 3 3 3 0 Cysteine-rich TM module stress tolerance DUF3402 PF11882.8 EGG21007.1 - 0.055 12.6 0.8 0.084 12.0 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Ctr PF04145.15 EGG21007.1 - 0.068 13.8 3.2 0.49 11.0 0.1 2.5 1 1 0 2 2 2 0 Ctr copper transporter family TMEM132D_C PF15706.5 EGG21007.1 - 0.16 11.8 0.0 0.16 11.8 0.0 3.2 4 0 0 4 4 4 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF2615 PF11027.8 EGG21007.1 - 0.2 11.8 6.0 2.3 8.4 0.0 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2615) Presenilin PF01080.17 EGG21007.1 - 0.95 8.2 2.7 1.7 7.3 2.7 1.5 1 0 0 1 1 1 0 Presenilin CRA PF06589.11 EGG21007.1 - 2 8.5 5.7 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) QWRF PF04484.12 EGG21007.1 - 2.3 7.9 8.1 4.7 6.9 8.1 1.4 1 0 0 1 1 1 0 QWRF family Pex14_N PF04695.13 EGG21007.1 - 5.5 7.6 12.8 13 6.4 12.8 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 EGG21007.1 - 6.4 7.8 12.8 3.5 8.6 4.8 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4834) Peptidase_M1 PF01433.20 EGG21009.1 - 1.6e-70 237.1 1.7 2.8e-70 236.3 1.7 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGG21009.1 - 7.4e-54 183.4 0.0 4.3e-53 180.9 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGG21009.1 - 9.9e-46 156.3 0.4 9.9e-46 156.3 0.4 2.4 3 0 0 3 3 3 1 Peptidase M1 N-terminal domain TIG_2 PF18020.1 EGG21009.1 - 0.57 10.8 2.8 4.7 7.9 0.2 3.2 3 0 0 3 3 3 0 TIG domain found in plexin Ank_3 PF13606.6 EGG21010.1 - 0.0088 16.5 0.5 5.2 8.0 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeat Telomere_reg-2 PF10193.9 EGG21010.1 - 0.027 14.9 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Telomere length regulation protein Ank_2 PF12796.7 EGG21010.1 - 0.034 14.8 0.1 0.18 12.4 0.1 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) PRIMA1 PF16101.5 EGG21011.1 - 0.0046 17.0 5.2 0.013 15.5 5.2 1.8 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Keratin_assoc PF09775.9 EGG21012.1 - 1.8e-31 108.5 11.8 3.1e-31 107.7 11.8 1.3 1 1 0 1 1 1 1 Keratinocyte-associated protein 2 Peptidase_M50B PF13398.6 EGG21012.1 - 0.024 14.3 5.9 0.019 14.6 4.8 1.3 1 1 0 1 1 1 0 Peptidase M50B-like FUSC-like PF12805.7 EGG21012.1 - 1.9 7.5 4.9 2.1 7.3 4.9 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS CDK2AP PF09806.9 EGG21013.1 - 0.0096 16.0 3.9 0.01 15.9 3.9 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Corona_nucleoca PF00937.18 EGG21013.1 - 0.063 12.3 11.7 0.07 12.2 11.7 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Prog_receptor PF02161.15 EGG21013.1 - 0.13 11.0 2.5 0.16 10.6 2.5 1.0 1 0 0 1 1 1 0 Progesterone receptor DUF2464 PF10240.9 EGG21013.1 - 0.26 10.8 10.2 0.33 10.5 10.2 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 Presenilin PF01080.17 EGG21013.1 - 2.9 6.5 8.4 3.2 6.4 8.4 1.1 1 0 0 1 1 1 0 Presenilin Dicty_CTDC PF00526.18 EGG21014.1 - 1.9e-11 43.6 192.9 4.3e-06 26.5 13.1 16.7 16 1 1 17 17 17 11 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGG21014.1 - 2.7e-09 37.0 0.0 5.6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 PA14 domain DUF3318 PF11780.8 EGG21014.1 - 0.082 12.9 0.8 0.3 11.0 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) DUF4834 PF16118.5 EGG21014.1 - 0.09 13.8 0.1 0.26 12.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2613 PF11021.8 EGG21014.1 - 3.7 7.7 10.9 9.8 6.4 10.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DEAD PF00270.29 EGG21016.1 - 9.5e-34 116.7 0.4 3.2e-33 115.0 0.3 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG21016.1 - 9e-29 100.1 2.5 3.6e-27 94.9 0.1 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF913 PF06025.12 EGG21016.1 - 3.7 6.4 17.4 0.25 10.3 1.8 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Zip PF02535.22 EGG21016.1 - 3.7 6.7 18.1 4.9 6.3 4.4 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Endostatin PF06482.11 EGG21016.1 - 6.2 6.2 11.7 11 5.4 0.1 2.6 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin LRR_5 PF13306.6 EGG21017.1 - 0.014 15.4 0.1 0.48 10.4 0.1 3.3 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) TUDOR PF00567.24 EGG21017.1 - 0.063 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Tudor domain FNIP PF05725.12 EGG21017.1 - 2.1 8.6 22.7 13 6.1 0.4 7.5 5 4 2 7 7 7 0 FNIP Repeat DUF5602 PF18197.1 EGG21018.1 - 0.21 12.1 0.0 0.32 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5602) FNIP PF05725.12 EGG21019.1 - 5.4e-07 29.7 1.3 0.0019 18.3 0.2 21.7 24 3 1 25 25 25 8 FNIP Repeat NAD_binding_8 PF13450.6 EGG21019.1 - 0.0024 18.0 0.0 5.9 7.2 0.0 3.5 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain DUF4865 PF16157.5 EGG21019.1 - 0.47 10.4 4.9 1.2 9.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4865) FNIP PF05725.12 EGG21020.1 - 5e-09 36.2 3.9 0.00087 19.4 0.0 4.5 4 1 2 6 6 6 3 FNIP Repeat F-box-like PF12937.7 EGG21021.1 - 0.02 14.8 1.7 0.044 13.7 0.2 2.3 3 0 0 3 3 3 0 F-box-like FNIP PF05725.12 EGG21022.1 - 4.7e-07 29.9 71.9 0.0072 16.5 1.1 14.9 12 4 3 15 15 15 7 FNIP Repeat DUF4865 PF16157.5 EGG21022.1 - 0.026 14.5 0.2 2.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4865) DUF150_C PF17384.2 EGG21022.1 - 0.17 12.1 0.1 2.9 8.1 0.0 2.3 2 0 0 2 2 2 0 RimP C-terminal SH3 domain FNIP PF05725.12 EGG21023.1 - 0.00015 21.8 32.6 0.019 15.1 0.1 8.6 9 0 0 9 9 9 4 FNIP Repeat F-box-like PF12937.7 EGG21023.1 - 0.12 12.3 1.4 0.23 11.4 0.2 2.1 2 0 0 2 2 2 0 F-box-like FNIP PF05725.12 EGG21024.1 - 1.3e-07 31.7 13.1 0.0015 18.6 0.1 3.7 4 1 0 4 4 4 2 FNIP Repeat Carn_acyltransf PF00755.20 EGG21024.1 - 0.021 13.5 0.0 0.023 13.3 0.0 1.1 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase Erf4 PF10256.9 EGG21025.1 - 6.5e-06 26.2 0.4 0.00058 20.0 0.4 2.4 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family MFS_1 PF07690.16 EGG21025.1 - 0.0024 16.9 3.2 0.003 16.5 3.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4191 PF13829.6 EGG21025.1 - 0.016 14.5 3.4 0.024 14.0 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) HXXEE PF13787.6 EGG21025.1 - 0.038 14.8 2.3 0.067 14.0 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif FA_desaturase PF00487.24 EGG21025.1 - 0.044 13.6 0.5 0.073 12.9 0.5 1.3 1 0 0 1 1 1 0 Fatty acid desaturase DUF3040 PF11239.8 EGG21025.1 - 0.26 11.6 4.2 0.44 10.9 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2207 PF09972.9 EGG21025.1 - 0.9 8.2 8.7 0.1 11.4 3.9 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) 2TM PF13239.6 EGG21025.1 - 2.6 8.4 6.3 4.6 7.6 6.3 1.3 1 0 0 1 1 1 0 2TM domain Syja_N PF02383.18 EGG21026.1 - 3.4e-67 227.0 0.2 9.3e-53 179.6 0.0 2.4 1 1 1 2 2 2 2 SacI homology domain C2 PF00168.30 EGG21026.1 - 0.038 14.3 0.0 0.096 13.0 0.0 1.7 1 0 0 1 1 1 0 C2 domain DUF2663 PF10864.8 EGG21027.1 - 0.62 10.5 6.8 0.11 13.0 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Flavoprotein PF02441.19 EGG21028.1 - 2.3e-33 115.2 0.0 2.9e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein tRNA-synt_1b PF00579.25 EGG21029.1 - 2.4e-65 220.8 0.0 4.1e-65 220.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 EGG21029.1 - 1.4e-05 24.7 0.0 3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain Bac_surface_Ag PF01103.23 EGG21030.1 - 6.2e-15 55.5 7.2 1.2e-14 54.5 7.2 1.4 1 1 0 1 1 1 1 Surface antigen CHAT PF12770.7 EGG21031.1 - 8.8e-36 123.8 0.1 6.3e-20 71.8 0.0 2.1 1 1 1 2 2 2 2 CHAT domain Peptidase_C50 PF03568.17 EGG21031.1 - 0.0016 17.7 8.6 0.19 10.8 3.5 2.1 1 1 1 2 2 2 2 Peptidase family C50 DUF2718 PF10918.8 EGG21031.1 - 0.017 15.6 1.2 0.038 14.5 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) RapH_N PF18801.1 EGG21031.1 - 0.11 12.6 0.5 21 5.3 0.1 2.4 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal Secretin_N_2 PF07655.13 EGG21031.1 - 0.3 11.7 7.5 0.67 10.5 7.5 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain BP28CT PF08146.12 EGG21033.1 - 3.2e-41 140.8 3.7 3.2e-41 140.8 3.7 5.6 6 1 0 6 6 6 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EGG21033.1 - 5.7e-17 62.1 6.0 5.7e-17 62.1 6.0 7.2 6 1 1 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 EGG21033.1 - 9.8e-05 22.7 0.3 4.8 7.7 0.0 4.6 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.22 EGG21033.1 - 0.0076 16.4 7.4 43 4.8 0.1 6.9 6 0 0 6 6 6 0 HEAT repeat DUF3993 PF13158.6 EGG21033.1 - 0.5 10.6 6.1 40 4.5 0.0 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3993) Suf PF05843.14 EGG21033.1 - 1.9 8.4 13.1 6.8 6.6 0.6 3.6 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) DNA_primase_S PF01896.19 EGG21034.1 - 2.4e-44 151.5 0.3 3.7e-44 150.9 0.3 1.3 1 0 0 1 1 1 1 DNA primase small subunit Ribosomal_L1 PF00687.21 EGG21035.1 - 3.7e-46 157.4 6.3 4.7e-46 157.1 6.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF2701 PF10857.8 EGG21035.1 - 0.27 11.3 1.2 0.88 9.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) FNIP PF05725.12 EGG21036.1 - 0.0011 19.1 10.1 0.74 10.0 0.4 5.2 4 1 1 5 5 5 3 FNIP Repeat Pkinase PF00069.25 EGG21037.1 - 1.3e-21 77.2 0.0 3.1e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EGG21037.1 - 5.2e-14 52.4 10.4 4.5e-06 27.3 0.4 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 EGG21037.1 - 1.9e-08 33.9 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 EGG21037.1 - 5.3e-05 23.1 0.0 0.15 12.4 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 EGG21037.1 - 0.0013 19.1 0.0 5.2 7.5 0.0 3.5 2 2 1 3 3 3 1 HEAT repeats ARS2 PF04959.13 EGG21037.1 - 0.82 10.0 2.9 2.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Arsenite-resistance protein 2 Sec8_exocyst PF04048.14 EGG21037.1 - 1 9.2 5.4 0.27 11.1 1.2 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF3689 PF12463.8 EGG21038.1 - 1.1e-21 77.5 6.0 2.2e-21 76.5 6.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) S6OS1 PF15676.5 EGG21039.1 - 0.0031 16.1 0.0 0.0034 16.0 0.0 1.0 1 0 0 1 1 1 1 Six6 opposite strand transcript 1 family Pkinase_Tyr PF07714.17 EGG21041.1 - 7.5e-27 94.2 0.0 1.7e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 EGG21041.1 - 1.2e-23 82.7 64.5 3.1e-05 24.2 0.4 8.8 7 1 1 8 8 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG21041.1 - 2.9e-21 75.0 47.7 5.3e-07 29.3 3.9 6.5 4 1 2 6 6 6 5 Leucine rich repeat Pkinase PF00069.25 EGG21041.1 - 2e-13 50.3 0.0 4.9e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain RGS PF00615.19 EGG21041.1 - 5.3e-12 46.1 0.2 1.9e-11 44.3 0.2 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain RhoGAP PF00620.27 EGG21041.1 - 2.4e-10 40.4 2.6 2.4e-10 40.4 2.6 3.0 3 0 0 3 3 3 1 RhoGAP domain COR PF16095.5 EGG21041.1 - 2.7e-10 40.4 0.4 4.9e-09 36.3 0.0 3.2 2 1 0 2 2 2 1 C-terminal of Roc, COR, domain Kelch_3 PF13415.6 EGG21041.1 - 1.3e-08 34.9 0.4 0.0053 17.0 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Roc PF08477.13 EGG21041.1 - 2.1e-06 28.0 0.1 1.2e-05 25.6 0.1 2.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Kelch_5 PF13854.6 EGG21041.1 - 7.4e-06 25.8 1.8 0.13 12.3 0.7 3.2 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 EGG21041.1 - 0.00013 22.1 1.1 1.1 9.6 0.1 3.3 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 EGG21041.1 - 0.00034 20.2 0.8 0.61 9.7 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 EGG21041.1 - 0.001 19.0 0.7 0.042 13.9 0.1 3.0 2 0 0 2 2 2 1 Galactose oxidase, central domain LRR_1 PF00560.33 EGG21041.1 - 0.0017 18.6 39.1 0.84 10.4 0.7 10.0 8 1 0 8 8 7 2 Leucine Rich Repeat LRR_9 PF14580.6 EGG21041.1 - 0.0021 17.6 27.8 0.1 12.1 2.0 4.5 1 1 1 3 3 3 2 Leucine-rich repeat Arf PF00025.21 EGG21041.1 - 0.0048 16.4 0.9 0.9 9.0 0.0 3.3 2 1 1 3 3 3 1 ADP-ribosylation factor family RGS-like PF09128.11 EGG21041.1 - 0.018 14.8 0.0 0.054 13.2 0.0 1.8 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain fn3_5 PF06280.12 EGG21042.1 - 0.063 14.0 0.1 0.081 13.6 0.1 1.1 1 0 0 1 1 1 0 Fn3-like domain RVT_1 PF00078.27 EGG21043.1 - 6.2e-08 32.4 0.0 9.5e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SSPI PF14098.6 EGG21043.1 - 0.7 10.1 2.2 1.2 9.4 0.2 2.1 2 0 0 2 2 2 0 Small, acid-soluble spore protein I MAGE PF01454.19 EGG21044.1 - 1.1e-34 120.0 0.1 1.1e-34 120.0 0.1 3.3 3 1 0 3 3 3 1 MAGE family DUF2052 PF09747.9 EGG21044.1 - 0.0032 17.6 0.8 0.0032 17.6 0.8 3.2 2 1 1 3 3 3 1 Coiled-coil domain containing protein (DUF2052) YL1 PF05764.13 EGG21044.1 - 0.015 15.5 32.6 0.025 14.7 5.1 2.2 2 0 0 2 2 2 0 YL1 nuclear protein SDA1 PF05285.12 EGG21044.1 - 0.019 14.4 33.4 0.36 10.2 8.2 2.2 2 0 0 2 2 2 0 SDA1 SAPS PF04499.15 EGG21044.1 - 0.027 13.3 18.2 0.34 9.6 11.4 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Otopetrin PF03189.13 EGG21044.1 - 0.054 12.3 1.5 3.9e+02 -0.4 0.0 2.2 1 1 0 2 2 2 0 Otopetrin BUD22 PF09073.10 EGG21044.1 - 0.24 10.7 37.7 0.24 10.7 18.4 2.4 2 0 0 2 2 2 0 BUD22 Menin PF05053.13 EGG21044.1 - 0.26 9.6 29.4 1.1 7.5 3.4 2.4 2 0 0 2 2 2 0 Menin Na_trans_assoc PF06512.13 EGG21044.1 - 1 9.6 23.9 0.43 10.8 1.3 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated LMBR1 PF04791.16 EGG21044.1 - 6.8 5.5 8.0 11 4.8 8.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Sigma70_ner PF04546.13 EGG21046.1 - 0.0012 18.8 5.1 0.0014 18.5 5.1 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region RNA_pol_3_Rpc31 PF11705.8 EGG21046.1 - 0.0025 18.1 9.4 0.003 17.9 9.4 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Radial_spoke PF04712.12 EGG21046.1 - 0.006 15.6 5.7 0.0075 15.3 5.7 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein RNA_pol_Rpc4 PF05132.14 EGG21046.1 - 0.01 16.3 0.8 0.014 15.9 0.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 PBP1_TM PF14812.6 EGG21046.1 - 0.021 15.2 5.6 0.038 14.4 5.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF5523 PF17661.1 EGG21046.1 - 0.022 14.5 9.0 0.029 14.1 9.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RR_TM4-6 PF06459.12 EGG21046.1 - 0.044 13.6 6.4 0.054 13.3 6.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RPA43_OB PF17875.1 EGG21046.1 - 0.044 14.4 3.2 0.074 13.7 3.2 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I PPP4R2 PF09184.11 EGG21046.1 - 0.047 13.3 9.7 0.057 13.0 9.7 1.1 1 0 0 1 1 1 0 PPP4R2 DUF4820 PF16091.5 EGG21046.1 - 0.049 13.0 1.0 0.066 12.6 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FAM176 PF14851.6 EGG21046.1 - 0.05 13.3 5.5 0.076 12.7 5.5 1.3 1 0 0 1 1 1 0 FAM176 family IFT57 PF10498.9 EGG21046.1 - 0.073 12.0 7.5 0.099 11.6 7.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RXT2_N PF08595.11 EGG21046.1 - 0.084 12.9 5.4 0.12 12.4 5.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Fmp27 PF10344.9 EGG21046.1 - 0.11 10.6 6.8 0.15 10.1 6.8 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 FancD2 PF14631.6 EGG21046.1 - 0.13 9.6 4.2 0.16 9.3 4.2 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease S-antigen PF05756.11 EGG21046.1 - 0.15 12.4 6.2 0.25 11.7 6.2 1.4 1 0 0 1 1 1 0 S-antigen protein RPN2_C PF18004.1 EGG21046.1 - 0.19 11.6 8.4 0.27 11.2 8.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 EGG21046.1 - 0.19 11.1 9.0 0.24 10.8 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pox_Ag35 PF03286.14 EGG21046.1 - 0.19 11.5 9.8 0.25 11.1 9.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF913 PF06025.12 EGG21046.1 - 0.19 10.7 1.6 0.21 10.5 1.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 EGG21046.1 - 0.19 9.8 12.6 0.25 9.4 12.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 EGG21046.1 - 0.23 10.6 5.7 0.3 10.3 5.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.11 EGG21046.1 - 0.54 8.7 4.4 0.61 8.6 4.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3464 PF11947.8 EGG21046.1 - 1.3 8.8 4.6 1.9 8.2 4.6 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 HSP90 PF00183.18 EGG21046.1 - 1.9 7.3 11.6 2.5 6.9 11.6 1.1 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.14 EGG21046.1 - 1.9 6.6 9.6 2.4 6.3 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 EGG21046.1 - 2.7 7.3 13.0 3.5 6.9 13.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Diphthamide_syn PF01866.17 EGG21047.1 - 0.2 11.0 3.5 0.34 10.3 3.5 1.5 1 0 0 1 1 1 0 Putative diphthamide synthesis protein GAGA_bind PF06217.12 EGG21047.1 - 0.75 10.0 13.3 1.4 9.1 0.2 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family CemA PF03040.14 EGG21047.1 - 1.8 8.4 8.5 4.1 7.3 8.5 1.5 1 0 0 1 1 1 0 CemA family Exonuc_VII_L PF02601.15 EGG21047.1 - 3.4 7.1 16.2 6.5 6.2 16.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit COPI_assoc PF08507.10 EGG21048.1 - 3.9e-18 65.8 8.0 5e-18 65.4 8.0 1.1 1 0 0 1 1 1 1 COPI associated protein DUF4064 PF13273.6 EGG21048.1 - 9.4 6.6 17.0 10 6.5 9.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Tup_N PF08581.10 EGG21049.1 - 1.6e-05 25.1 5.7 2.7e-05 24.4 5.7 1.4 1 0 0 1 1 1 1 Tup N-terminal Fez1 PF06818.15 EGG21049.1 - 0.00017 22.1 0.7 0.00025 21.5 0.7 1.3 1 0 0 1 1 1 1 Fez1 ADIP PF11559.8 EGG21049.1 - 0.0017 18.5 7.8 0.0042 17.2 7.8 1.6 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 EGG21049.1 - 0.0055 17.0 7.9 0.0055 17.0 7.9 1.8 1 1 1 2 2 2 1 Csm1 N-terminal domain Spc7 PF08317.11 EGG21049.1 - 0.0081 15.1 6.6 0.011 14.6 6.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF641 PF04859.12 EGG21049.1 - 0.013 15.8 1.4 0.013 15.8 1.4 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) BST2 PF16716.5 EGG21049.1 - 0.017 15.7 4.0 0.017 15.7 4.0 1.8 2 0 0 2 2 1 0 Bone marrow stromal antigen 2 APG6_N PF17675.1 EGG21049.1 - 0.026 15.0 5.6 0.04 14.4 5.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region TMPIT PF07851.13 EGG21049.1 - 0.035 13.3 2.3 0.052 12.8 2.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein PKcGMP_CC PF16808.5 EGG21049.1 - 0.065 13.1 1.0 0.065 13.1 1.0 2.4 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase USP8_interact PF08941.10 EGG21049.1 - 0.074 12.9 3.7 0.13 12.1 3.7 1.3 1 0 0 1 1 1 0 USP8 interacting DUF724 PF05266.14 EGG21049.1 - 0.11 12.4 3.6 0.16 11.8 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PhoU PF01895.19 EGG21049.1 - 0.11 13.0 0.6 0.21 12.0 0.6 1.4 1 0 0 1 1 1 0 PhoU domain TMCO5 PF14992.6 EGG21049.1 - 0.14 11.7 6.9 0.24 10.9 6.9 1.4 1 0 0 1 1 1 0 TMCO5 family bZIP_2 PF07716.15 EGG21049.1 - 0.21 11.7 10.4 0.93 9.6 0.2 2.4 2 0 0 2 2 2 0 Basic region leucine zipper UPF0242 PF06785.11 EGG21049.1 - 0.34 11.0 9.3 0.53 10.4 9.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 EGG21049.1 - 0.45 10.7 7.4 0.14 12.3 1.2 2.4 1 1 2 3 3 3 0 bZIP transcription factor OmpH PF03938.14 EGG21049.1 - 0.5 10.7 4.8 0.74 10.2 4.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMF_DNA_bd PF12329.8 EGG21049.1 - 0.54 10.3 11.3 0.19 11.8 6.5 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-H PF05837.12 EGG21049.1 - 0.77 10.2 5.7 1.5 9.3 5.7 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HOOK PF05622.12 EGG21049.1 - 0.81 7.8 9.9 1.1 7.4 9.9 1.1 1 0 0 1 1 1 0 HOOK protein DUF3450 PF11932.8 EGG21049.1 - 0.93 8.7 8.1 1.9 7.7 3.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spc24 PF08286.11 EGG21049.1 - 3.3 8.0 8.6 0.31 11.3 3.4 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.15 EGG21049.1 - 6.9 6.5 7.8 1.2 8.9 1.1 2.2 1 1 1 2 2 2 0 Septum formation initiator RhoGEF PF00621.20 EGG21050.1 - 4.5e-48 163.9 2.6 4.5e-48 163.9 2.6 2.4 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 EGG21050.1 - 4.7e-19 68.3 7.4 9.1e-19 67.4 7.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 EGG21050.1 - 3.9e-10 40.2 0.7 1.1e-09 38.7 0.7 1.8 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 EGG21050.1 - 0.0094 16.2 4.2 0.021 15.0 4.2 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger zf-C2H2_11 PF16622.5 EGG21050.1 - 0.17 11.7 3.9 0.18 11.6 1.1 2.5 1 1 1 2 2 2 0 zinc-finger C2H2-type PH_11 PF15413.6 EGG21050.1 - 2 8.9 7.4 0.21 12.0 0.7 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain DZR PF12773.7 EGG21050.1 - 6.4 6.9 8.7 1.3e+02 2.7 8.7 2.4 1 1 0 1 1 1 0 Double zinc ribbon PHD PF00628.29 EGG21053.1 - 2.1e-10 40.3 12.8 5.9e-10 38.9 12.8 1.8 1 0 0 1 1 1 1 PHD-finger Ipi1_N PF12333.8 EGG21054.1 - 1.9e-13 50.9 1.2 1.9e-13 50.9 1.2 3.0 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.6 EGG21054.1 - 0.011 16.1 0.1 0.12 12.7 0.1 2.4 2 0 0 2 2 2 0 HEAT repeats RPN2_C PF18004.1 EGG21054.1 - 0.023 14.6 0.6 0.044 13.7 0.6 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Vac14_Fab1_bd PF12755.7 EGG21054.1 - 0.11 13.1 1.8 0.31 11.7 0.0 2.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Imm43 PF15570.6 EGG21054.1 - 0.16 12.0 1.6 1.6 8.7 0.0 3.0 3 0 0 3 3 3 0 Immunity protein 43 PSRP-3_Ycf65 PF04839.13 EGG21054.1 - 0.16 12.2 0.1 45 4.4 0.1 3.1 2 0 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) CLASP_N PF12348.8 EGG21054.1 - 1.1 8.7 12.4 0.19 11.3 1.3 4.2 4 1 1 5 5 5 0 CLASP N terminal TFIIS_C PF01096.18 EGG21055.1 - 2.9e-15 55.8 2.7 2.9e-15 55.8 2.7 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGG21055.1 - 5.9e-06 26.0 7.3 9.8e-05 22.1 1.2 3.6 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 EGG21055.1 - 0.0046 16.9 1.1 0.0046 16.9 1.1 2.7 2 1 0 2 2 2 1 Double zinc ribbon zf-C4_Topoisom PF01396.19 EGG21055.1 - 0.0053 16.5 5.4 0.15 11.9 0.6 3.7 3 0 0 3 3 3 1 Topoisomerase DNA binding C4 zinc finger Anti-TRAP PF15777.5 EGG21055.1 - 0.049 13.6 1.1 9.8 6.2 0.0 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ribosomal_S27e PF01667.17 EGG21055.1 - 0.095 12.4 7.0 0.6 9.8 0.8 2.7 2 1 0 2 2 2 0 Ribosomal protein S27 Nop14 PF04147.12 EGG21055.1 - 0.1 10.8 50.8 0.18 10.0 50.8 1.4 1 0 0 1 1 1 0 Nop14-like family PADR1 PF08063.12 EGG21055.1 - 0.16 11.8 5.2 0.36 10.7 0.1 3.0 2 1 1 3 3 3 0 PADR1 (NUC008) domain Zn_Tnp_IS1595 PF12760.7 EGG21055.1 - 0.18 11.8 6.7 1 9.4 0.3 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Red1 PF07964.11 EGG21055.1 - 0.41 8.8 52.5 0.45 8.7 52.5 1.1 1 0 0 1 1 1 0 Rec10 / Red1 zinc_ribbon_9 PF14369.6 EGG21055.1 - 0.54 10.6 3.8 24 5.3 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon Mu-like_Com PF10122.9 EGG21055.1 - 0.86 9.1 3.6 15 5.1 0.1 2.8 1 1 1 2 2 2 0 Mu-like prophage protein Com AF-4 PF05110.13 EGG21055.1 - 1.1 7.3 56.6 1.2 7.2 56.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3716 PF12511.8 EGG21055.1 - 1.1 9.3 4.8 2 8.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) LAP1C PF05609.12 EGG21055.1 - 1.2 8.1 39.4 1.6 7.8 39.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 EGG21055.1 - 1.4 7.4 44.9 1.5 7.3 44.9 1.1 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 EGG21055.1 - 3.8 5.5 38.3 5.5 5.0 38.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-ribbon_3 PF13248.6 EGG21055.1 - 3.9 7.0 10.7 4.2 6.9 0.6 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Mitofilin PF09731.9 EGG21055.1 - 4.4 6.0 43.7 5.5 5.7 43.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Nudix_N_2 PF14803.6 EGG21055.1 - 4.4 7.3 6.0 19 5.3 1.5 3.0 2 1 0 2 2 2 0 Nudix N-terminal DNA_RNApol_7kD PF03604.13 EGG21055.1 - 8 6.2 7.5 6.4 6.5 0.1 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit HPP PF04982.13 EGG21056.1 - 0.11 12.7 2.8 0.6 10.3 0.4 2.4 2 0 0 2 2 2 0 HPP family MAGE PF01454.19 EGG21056.1 - 0.22 11.2 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 MAGE family WD40 PF00400.32 EGG21057.1 - 1.3e-18 66.9 0.3 0.0074 17.1 0.0 5.7 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG21057.1 - 2.7e-14 53.2 0.0 2.8e-05 24.3 0.0 5.1 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG21057.1 - 0.0001 21.1 0.1 0.22 10.1 0.1 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGG21057.1 - 0.0021 17.1 0.5 0.84 8.5 0.0 3.4 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 EGG21057.1 - 0.0064 16.5 0.0 0.38 10.8 0.0 2.5 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 EGG21057.1 - 0.024 13.4 0.0 3.5 6.3 0.0 2.6 3 0 0 3 3 3 0 Nup133 N terminal like Frtz PF11768.8 EGG21057.1 - 0.08 11.2 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz SelK_SelG PF10961.8 EGG21058.1 - 0.085 13.5 1.6 0.47 11.1 0.3 2.8 2 0 0 2 2 2 0 Selenoprotein SelK_SelG RINGv PF12906.7 EGG21059.1 - 9.2e-15 54.5 8.8 1.5e-14 53.8 8.8 1.4 1 0 0 1 1 1 1 RING-variant domain DUF2722 PF10846.8 EGG21059.1 - 0.011 14.7 5.9 0.63 8.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) zf-RING_2 PF13639.6 EGG21059.1 - 0.015 15.6 7.6 0.028 14.8 7.6 1.4 1 0 0 1 1 1 0 Ring finger domain Pex14_N PF04695.13 EGG21059.1 - 0.037 14.7 13.1 0.053 14.2 4.6 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pep1_7 PF17232.2 EGG21059.1 - 0.088 13.3 0.1 0.31 11.5 0.1 2.0 1 0 0 1 1 1 0 Elicitor peptide 1-7 Nop14 PF04147.12 EGG21059.1 - 0.25 9.5 4.1 0.43 8.7 4.1 1.2 1 0 0 1 1 1 0 Nop14-like family zf-ANAPC11 PF12861.7 EGG21059.1 - 0.37 10.9 3.1 0.79 9.8 3.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Tim54 PF11711.8 EGG21059.1 - 0.81 8.4 4.6 1.5 7.5 0.1 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.6 EGG21059.1 - 5.2 6.7 7.0 0.22 11.2 0.8 1.8 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 EGG21059.1 - 8 4.4 12.5 12 3.9 12.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ank_2 PF12796.7 EGG21060.1 - 1.6e-33 115.1 19.8 9.9e-06 26.1 0.1 7.4 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG21060.1 - 1.5e-32 111.6 13.9 6.3e-05 23.4 0.1 10.1 6 3 3 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG21060.1 - 3.9e-24 84.4 14.7 0.015 15.6 0.0 13.1 6 4 10 16 16 16 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG21060.1 - 1.1e-15 56.1 6.7 14 6.7 0.0 14.8 16 1 1 17 17 17 2 Ankyrin repeat Ank PF00023.30 EGG21060.1 - 3.3e-05 24.1 0.6 77 4.0 0.0 7.8 6 4 1 7 7 7 0 Ankyrin repeat LisH PF08513.11 EGG21060.1 - 0.035 14.1 0.1 0.035 14.1 0.1 3.3 4 0 0 4 4 4 0 LisH Methyltransf_7 PF03492.15 EGG21061.1 - 4.8e-39 134.5 0.6 5.8e-39 134.2 0.6 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase TINF2_N PF14973.6 EGG21061.1 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus IGR PF09597.10 EGG21062.1 - 4.7e-24 84.2 0.2 9e-24 83.3 0.2 1.5 1 0 0 1 1 1 1 IGR protein motif BMF PF15185.6 EGG21062.1 - 0.21 11.3 2.9 0.35 10.6 2.9 1.3 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis RAP1 PF07218.11 EGG21062.1 - 1.4 7.1 5.6 1.8 6.7 5.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sporozoite_P67 PF05642.11 EGG21062.1 - 2.4 6.1 10.9 4 5.4 10.8 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Presenilin PF01080.17 EGG21062.1 - 6.4 5.4 6.2 8.2 5.1 6.2 1.2 1 0 0 1 1 1 0 Presenilin p450 PF00067.22 EGG21063.1 - 3e-81 273.5 0.0 3.4e-81 273.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 EGG21064.1 - 3.2e-19 69.3 0.0 5e-10 39.8 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGG21064.1 - 1.9e-10 40.7 0.0 0.00014 22.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EGG21064.1 - 4.9e-10 39.8 0.0 8.9e-07 29.3 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG21064.1 - 5.3e-08 32.5 0.1 0.02 15.4 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EGG21064.1 - 7.1e-07 29.4 0.1 0.0001 22.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) BUD22 PF09073.10 EGG21065.1 - 0.0023 17.4 26.1 0.0053 16.2 26.1 1.6 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.13 EGG21065.1 - 0.074 13.0 33.2 0.12 12.4 33.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TRAPP PF04051.16 EGG21066.1 - 2e-37 128.1 0.4 2.7e-37 127.7 0.4 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SOG2 PF10428.9 EGG21066.1 - 0.0081 15.4 7.9 0.0089 15.3 7.9 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein DUF908 PF06012.12 EGG21066.1 - 6 6.2 10.1 8.3 5.7 10.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Peptidase_M16_C PF05193.21 EGG21067.1 - 4.4e-16 59.4 0.0 5.1e-15 55.9 0.0 2.4 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGG21067.1 - 8e-09 35.6 0.2 2.3e-07 30.9 0.0 3.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 EGG21067.1 - 0.014 14.6 0.1 0.014 14.6 0.1 4.4 4 0 0 4 4 4 0 Peptidase M16C associated Prefoldin PF02996.17 EGG21067.1 - 0.16 11.8 3.9 0.86 9.5 1.1 2.8 2 0 0 2 2 2 0 Prefoldin subunit Fe-S_biosyn PF01521.20 EGG21068.1 - 1.5e-11 44.5 0.4 2.3e-11 43.9 0.4 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF4270 PF14092.6 EGG21068.1 - 0.00082 18.6 1.8 0.00086 18.5 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4270) RNA_pol_Rpb1_3 PF04983.18 EGG21068.1 - 0.036 14.0 0.1 0.036 14.0 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 SR-25 PF10500.9 EGG21068.1 - 1.7 8.2 7.5 2 7.9 7.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BES1_N PF05687.13 EGG21069.1 - 8.8 6.7 9.4 16 5.8 9.4 1.4 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Pkinase PF00069.25 EGG21070.1 - 4.7e-67 226.1 0.0 1.6e-66 224.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21070.1 - 1.2e-49 168.9 0.0 1.9e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Lipoxygenase PF00305.19 EGG21070.1 - 1.3e-24 86.6 0.0 1.5e-14 53.4 0.0 2.1 1 1 0 2 2 2 2 Lipoxygenase Pkinase_fungal PF17667.1 EGG21070.1 - 1.2e-06 27.6 0.1 2.6e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGG21070.1 - 0.00014 21.3 0.0 0.00032 20.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGG21070.1 - 0.087 12.2 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Allexi_40kDa PF05549.11 EGG21070.1 - 1.4 8.4 4.6 0.16 11.4 0.1 1.7 2 0 0 2 2 2 0 Allexivirus 40kDa protein Myc_N PF01056.18 EGG21070.1 - 3.9 7.3 8.4 18 5.1 0.1 2.4 2 0 0 2 2 2 0 Myc amino-terminal region HATPase_c PF02518.26 EGG21071.1 - 1.7e-26 92.9 0.0 4.9e-26 91.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGG21071.1 - 6.4e-19 68.2 0.0 1.8e-18 66.7 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGG21071.1 - 2.7e-08 33.7 0.2 7.7e-05 22.6 0.0 2.9 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 EGG21071.1 - 2.3e-07 30.7 0.0 3.2e-06 27.0 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 EGG21071.1 - 5.9e-07 29.7 0.4 4.9e-06 26.7 0.1 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EGG21071.1 - 0.00021 21.5 0.0 0.0009 19.5 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGG21071.1 - 0.011 15.8 0.0 0.011 15.8 0.0 3.8 2 2 0 2 2 1 0 PAS fold EPL1 PF10513.9 EGG21071.1 - 0.035 14.5 23.0 0.075 13.4 10.9 3.7 3 0 0 3 3 3 0 Enhancer of polycomb-like PAS_4 PF08448.10 EGG21071.1 - 0.042 14.1 0.0 0.17 12.2 0.0 2.1 1 0 0 1 1 1 0 PAS fold Tim54 PF11711.8 EGG21071.1 - 1 8.0 15.3 1 8.1 11.5 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Otopetrin PF03189.13 EGG21071.1 - 2.2 7.0 9.5 0.098 11.5 2.4 2.3 3 0 0 3 3 3 0 Otopetrin DUF4638 PF15472.6 EGG21071.1 - 2.7 7.7 11.9 0.46 10.2 7.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) V_ATPase_I PF01496.19 EGG21071.1 - 9.5 4.0 15.8 0.2 9.5 8.3 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SSP160 PF06933.11 EGG21072.1 - 0.16 10.1 21.5 0.14 10.3 21.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TMCO5 PF14992.6 EGG21072.1 - 0.21 11.1 1.7 0.21 11.2 1.7 1.0 1 0 0 1 1 1 0 TMCO5 family Mucin PF01456.17 EGG21072.1 - 0.37 10.8 26.7 0.39 10.7 26.7 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein AJAP1_PANP_C PF15298.6 EGG21072.1 - 0.65 10.2 14.3 0.71 10.1 14.3 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus ETX_MTX2 PF03318.13 EGG21072.1 - 1 9.1 22.8 1.2 8.9 22.8 1.1 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 FSA_C PF10479.9 EGG21072.1 - 4.1 5.4 12.3 4.1 5.4 12.3 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 EGG21072.1 - 5.7 4.8 13.5 5.9 4.7 13.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TMEM154 PF15102.6 EGG21072.1 - 6.4 6.7 9.1 6.7 6.6 9.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family Metallophos PF00149.28 EGG21073.1 - 7.5e-13 49.4 1.5 7.5e-13 49.4 1.5 2.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Mad3_BUB1_I PF08311.12 EGG21073.1 - 0.056 13.4 1.5 12 5.9 0.1 3.6 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 SET PF00856.28 EGG21074.1 - 8.6e-24 84.8 0.2 8.6e-24 84.8 0.2 5.1 3 1 0 4 4 4 1 SET domain Pre-SET PF05033.16 EGG21074.1 - 1.6e-12 48.0 7.6 1.6e-12 48.0 7.6 3.3 4 0 0 4 4 4 1 Pre-SET motif LSM PF01423.22 EGG21075.1 - 1.9e-09 37.0 0.0 2.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EGG21075.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 RimP C-terminal SH3 domain DUF3364 PF11844.8 EGG21075.1 - 0.0029 17.8 2.8 0.075 13.3 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3364) SM-ATX PF14438.6 EGG21075.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF4834 PF16118.5 EGG21076.1 - 0.016 16.2 2.5 0.02 15.8 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CPSF100_C PF13299.6 EGG21076.1 - 0.03 14.5 2.5 0.035 14.3 2.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF1980 PF09323.10 EGG21076.1 - 0.044 13.7 1.2 0.045 13.7 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Presenilin PF01080.17 EGG21076.1 - 0.11 11.3 2.3 0.13 11.0 2.3 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EGG21076.1 - 2.1 7.5 3.5 2.4 7.3 3.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter LRR_6 PF13516.6 EGG21078.1 - 2.3e-09 36.5 40.8 0.056 13.5 0.4 9.4 11 0 0 11 11 11 4 Leucine Rich repeat F-box-like PF12937.7 EGG21078.1 - 0.023 14.6 0.5 0.043 13.7 0.5 1.5 1 0 0 1 1 1 0 F-box-like YusW PF14039.6 EGG21078.1 - 0.39 11.3 4.0 13 6.3 0.2 2.8 3 0 0 3 3 3 0 YusW-like protein LRR_4 PF12799.7 EGG21078.1 - 0.42 11.1 47.0 0.16 12.4 2.3 7.4 3 2 5 9 9 9 0 Leucine Rich repeats (2 copies) Rubis-subs-bind PF09273.11 EGG21082.1 - 1.9e-26 93.3 1.8 3.8e-26 92.3 1.8 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EGG21082.1 - 1.8e-11 44.7 0.1 8.5e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 SET domain CBM49 PF09478.10 EGG21082.1 - 2.3e-10 40.7 2.2 4.2e-09 36.6 1.4 3.0 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 RGS PF00615.19 EGG21082.1 - 0.28 11.5 3.2 0.34 11.2 1.8 1.9 2 0 0 2 2 2 0 Regulator of G protein signaling domain DUF2828 PF11443.8 EGG21083.1 - 1.8e-125 419.5 3.5 5.8e-102 341.8 1.9 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF2828) VWA_CoxE PF05762.14 EGG21083.1 - 0.00073 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 EGG21083.1 - 0.082 13.6 0.0 0.35 11.5 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Rad60-SLD PF11976.8 EGG21086.1 - 0.054 13.3 0.5 0.074 12.9 0.5 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like NCKAP5 PF15246.6 EGG21087.1 - 3 7.4 5.0 17 4.9 2.4 2.1 2 0 0 2 2 2 0 Nck-associated protein 5, Peripheral clock protein SET PF00856.28 EGG21088.1 - 4.2e-10 40.3 2.1 5e-09 36.8 0.1 2.6 2 1 0 2 2 2 1 SET domain DivIC PF04977.15 EGG21089.1 - 0.0021 17.8 1.9 0.0021 17.8 1.9 1.7 2 0 0 2 2 2 1 Septum formation initiator BCDHK_Adom3 PF10436.9 EGG21089.1 - 0.0035 17.2 0.7 0.0035 17.2 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase CorA PF01544.18 EGG21089.1 - 0.0068 15.8 2.1 0.0075 15.6 2.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SlyX PF04102.12 EGG21089.1 - 0.01 16.4 1.1 0.01 16.4 1.1 1.6 2 0 0 2 2 2 0 SlyX TMF_DNA_bd PF12329.8 EGG21089.1 - 0.014 15.4 0.7 0.014 15.4 0.7 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TSC22 PF01166.18 EGG21089.1 - 0.03 14.6 0.6 0.071 13.4 0.4 1.9 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 EGG21089.1 - 0.097 12.8 0.6 0.18 11.9 0.6 1.6 1 1 0 1 1 1 0 bZIP transcription factor AraC_N PF06719.13 EGG21089.1 - 0.11 12.2 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus DUF5003 PF16394.5 EGG21089.1 - 0.14 11.3 2.1 0.14 11.3 2.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5003) TLV_coat PF00429.19 EGG21089.1 - 0.17 10.5 0.8 0.22 10.1 0.8 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) ZapB PF06005.12 EGG21089.1 - 0.22 12.0 4.6 0.18 12.3 3.0 1.8 1 1 1 2 2 2 0 Cell division protein ZapB DUF1079 PF06435.11 EGG21089.1 - 0.47 10.7 6.3 1.4 9.2 0.7 2.7 2 1 1 3 3 3 0 Repeat of unknown function (DUF1079) DREV PF05219.12 EGG21090.1 - 2.8e-53 180.7 3.6 1.2e-40 139.3 0.0 2.1 2 0 0 2 2 2 2 DREV methyltransferase Methyltransf_11 PF08241.12 EGG21090.1 - 2.2e-12 47.4 0.1 1.2e-11 45.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG21090.1 - 7.1e-10 39.5 1.7 4.8e-08 33.6 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG21090.1 - 2.4e-08 34.0 0.0 5.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG21090.1 - 4.3e-08 33.7 0.0 1.1e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG21090.1 - 3.6e-05 23.6 0.1 0.00069 19.4 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain DHR10 PF18595.1 EGG21090.1 - 7.8 6.6 9.5 4.2 7.5 2.3 2.8 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Brix PF04427.18 EGG21091.1 - 4.5e-41 141.1 0.3 9.6e-41 140.0 0.3 1.5 1 0 0 1 1 1 1 Brix domain Josephin PF02099.17 EGG21092.1 - 4.6e-50 169.9 0.2 4.6e-50 169.9 0.2 2.4 3 0 0 3 3 3 1 Josephin UIM PF02809.20 EGG21092.1 - 0.00029 20.5 12.0 0.98 9.5 0.0 4.3 4 0 0 4 4 4 3 Ubiquitin interaction motif Mucin PF01456.17 EGG21092.1 - 0.063 13.3 11.2 0.11 12.5 11.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Cwf_Cwc_15 PF04889.12 EGG21092.1 - 0.88 9.3 13.8 0.13 12.0 7.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SWI2_SNF2 PF18766.1 EGG21093.1 - 1.3e-24 87.1 0.2 1.3e-24 87.1 0.2 2.2 2 0 0 2 2 2 1 SWI2/SNF2 ATPase ResIII PF04851.15 EGG21093.1 - 1.1e-11 45.0 0.4 1.1e-11 45.0 0.4 4.0 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit Surp PF01805.20 EGG21093.1 - 2.6e-06 27.3 0.0 6.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Surp module HEAT_2 PF13646.6 EGG21093.1 - 0.02 15.3 0.1 0.081 13.3 0.1 2.1 1 1 0 1 1 1 0 HEAT repeats Ank_2 PF12796.7 EGG21094.1 - 3.4e-21 75.6 20.9 2.3e-08 34.5 0.7 5.2 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG21094.1 - 4.6e-16 59.0 7.0 0.00094 19.7 0.1 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG21094.1 - 2.8e-14 53.0 7.0 0.028 14.7 0.1 8.5 3 3 6 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG21094.1 - 4.1e-14 51.3 5.4 0.0036 17.7 0.1 8.9 8 1 1 9 9 9 2 Ankyrin repeat Ank PF00023.30 EGG21094.1 - 8.8e-06 25.9 5.6 0.007 16.8 0.1 6.1 4 2 0 4 4 4 1 Ankyrin repeat RhoGAP PF00620.27 EGG21095.1 - 2.7e-19 69.5 0.1 5.6e-19 68.5 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain Motile_Sperm PF00635.26 EGG21095.1 - 0.002 17.9 0.4 0.002 17.9 0.4 2.4 3 0 0 3 3 3 1 MSP (Major sperm protein) domain BAF1_ABF1 PF04684.13 EGG21096.1 - 0.46 9.5 24.9 0.56 9.2 24.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor AAA_12 PF13087.6 EGG21097.1 - 8.1e-42 143.1 1.6 2.2e-41 141.7 1.6 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGG21097.1 - 1.7e-22 80.5 1.1 1.7e-22 80.5 1.1 3.9 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGG21097.1 - 1.3e-08 34.8 0.0 9.8e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGG21097.1 - 2.9e-08 34.2 0.0 7.3e-07 29.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EGG21097.1 - 2.9e-06 26.8 0.1 0.00011 21.6 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EGG21097.1 - 0.00084 19.4 0.7 0.00084 19.4 0.7 3.2 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit ATPase PF06745.13 EGG21097.1 - 0.01 15.2 0.2 0.044 13.1 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.6 EGG21097.1 - 0.016 15.5 0.0 0.43 10.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGG21097.1 - 0.03 14.7 0.0 0.083 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 EGG21097.1 - 0.09 12.2 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 EGG21097.1 - 0.094 12.7 0.0 0.49 10.4 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGG21097.1 - 0.11 12.9 0.1 1.4 9.4 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TIG PF01833.24 EGG21098.1 - 1.5e-55 185.2 141.8 1.6e-10 40.9 10.7 15.7 15 0 0 15 15 15 11 IPT/TIG domain EGF_2 PF07974.13 EGG21098.1 - 0.00045 20.5 6.1 0.0009 19.6 6.1 1.6 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG21098.1 - 0.099 12.7 7.1 0.26 11.4 7.1 1.8 1 0 0 1 1 1 0 Tenascin EGF domain hEGF PF12661.7 EGG21098.1 - 6.3 7.6 6.8 21 6.0 6.8 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF VWA_N PF08399.11 EGG21099.1 - 0.0025 18.3 2.9 0.0053 17.2 0.0 2.8 3 0 0 3 3 3 1 VWA N-terminal TBPIP PF07106.13 EGG21100.1 - 1.3e-11 44.3 0.2 4.1e-11 42.6 0.2 1.8 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 EGG21100.1 - 6.9e-10 38.9 4.3 6.9e-10 38.9 4.3 2.8 2 1 1 3 3 2 1 Leucine zipper with capping helix domain Uso1_p115_C PF04871.13 EGG21100.1 - 0.0017 18.7 14.6 0.0017 18.7 14.6 2.7 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.12 EGG21100.1 - 0.022 15.2 7.0 0.022 15.2 7.0 2.9 1 1 1 2 2 2 0 Cell division protein ZapB Mnd1 PF03962.15 EGG21100.1 - 0.023 14.9 6.6 0.051 13.9 0.0 2.8 3 0 0 3 3 3 0 Mnd1 HTH domain Herpes_BLRF2 PF05812.12 EGG21100.1 - 0.025 14.7 13.8 0.037 14.1 4.8 3.3 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein bZIP_2 PF07716.15 EGG21100.1 - 0.026 14.6 1.7 0.026 14.6 1.7 3.5 1 1 2 3 3 3 0 Basic region leucine zipper Syntaxin-6_N PF09177.11 EGG21100.1 - 0.04 14.5 8.9 0.1 13.1 8.9 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal NRBF2 PF08961.10 EGG21100.1 - 0.098 12.2 10.9 0.6 9.7 9.9 2.7 1 1 2 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator DUF4777 PF16007.5 EGG21100.1 - 0.12 12.7 0.1 2.4 8.5 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4777) DivIC PF04977.15 EGG21100.1 - 0.52 10.1 18.4 0.8 9.5 3.5 3.3 1 1 2 3 3 3 0 Septum formation initiator FGAR-AT_linker PF18072.1 EGG21100.1 - 0.57 10.8 2.6 12 6.5 0.1 3.1 2 1 2 4 4 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain LMBR1 PF04791.16 EGG21100.1 - 0.83 8.5 8.0 0.89 8.4 8.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 EGG21100.1 - 0.85 8.9 10.1 1 8.6 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 EGG21100.1 - 0.91 9.7 18.3 2.9 8.1 8.5 3.6 2 1 1 3 3 2 0 bZIP transcription factor CENP-H PF05837.12 EGG21100.1 - 1.2 9.5 16.4 0.51 10.8 13.3 2.0 2 1 0 2 2 2 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 EGG21100.1 - 1.3 9.1 17.9 2.1 8.4 17.0 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus K-box PF01486.17 EGG21100.1 - 2.1 8.6 15.4 9.3 6.5 9.4 2.5 1 1 1 2 2 2 0 K-box region RasGAP_C PF03836.15 EGG21100.1 - 3 8.0 15.3 7.4 6.7 7.2 3.1 1 1 1 3 3 3 0 RasGAP C-terminus V_ATPase_I PF01496.19 EGG21100.1 - 3.2 5.5 8.6 4.1 5.2 8.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 EGG21100.1 - 6.8 5.4 8.2 7.7 5.2 8.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter YabA PF06156.13 EGG21100.1 - 7.6 7.2 12.4 6.8e+02 1.0 12.4 2.6 1 1 0 1 1 1 0 Initiation control protein YabA DUF4140 PF13600.6 EGG21100.1 - 9.5 6.7 9.8 9.1 6.8 7.0 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) zf-RING_2 PF13639.6 EGG21101.1 - 1.1e-10 41.6 9.0 2e-10 40.8 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGG21101.1 - 5.9e-10 38.9 9.9 1.1e-09 38.0 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGG21101.1 - 8.2e-09 35.6 7.2 1.8e-08 34.5 7.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGG21101.1 - 8.3e-09 35.3 3.0 8.3e-09 35.3 3.0 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG21101.1 - 1.7e-08 34.2 9.5 2.8e-08 33.5 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG21101.1 - 2.1e-07 30.7 7.7 3.2e-07 30.1 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG21101.1 - 7.7e-06 25.7 11.5 2.9e-05 23.8 3.3 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGG21101.1 - 2.4e-05 24.3 2.1 4.1e-05 23.6 2.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGG21101.1 - 2.4e-05 24.2 7.7 5.6e-05 23.0 7.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGG21101.1 - 6.1e-05 23.1 9.9 0.00011 22.3 9.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EGG21101.1 - 0.00078 19.2 5.3 0.0019 18.0 5.3 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 EGG21101.1 - 0.04 13.7 3.5 0.084 12.6 3.5 1.6 1 0 0 1 1 1 0 RING-like zinc finger FdhE PF04216.12 EGG21101.1 - 0.049 13.5 3.7 0.079 12.8 3.7 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Siva PF05458.12 EGG21101.1 - 0.077 12.7 3.5 0.12 12.1 3.5 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Rad50_zn_hook PF04423.14 EGG21101.1 - 0.083 12.7 0.5 3.4 7.6 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 EGG21101.1 - 0.15 11.9 8.1 0.44 10.4 7.9 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGG21101.1 - 0.19 11.9 4.7 0.35 11.0 4.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EGG21101.1 - 0.54 10.2 4.7 1.6 8.7 4.7 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 EGG21101.1 - 0.77 9.8 6.9 2 8.5 6.9 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-P11 PF03854.14 EGG21101.1 - 1.1 9.0 10.9 0.47 10.1 3.5 2.3 1 1 1 2 2 2 0 P-11 zinc finger zinc-ribbons_6 PF07191.12 EGG21101.1 - 1.4 8.9 6.8 2.4 8.2 6.8 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-MIZ PF02891.20 EGG21101.1 - 7.1 6.5 12.1 8.2 6.3 9.4 2.4 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger Dicty_CTDC PF00526.18 EGG21103.1 - 5.4e-63 208.4 395.1 3.7e-08 33.1 15.1 24.2 23 3 2 25 25 25 18 Dictyostelium (slime mold) repeat LRR_6 PF13516.6 EGG21105.1 - 1.3e-06 28.0 34.0 1.3 9.3 0.0 11.5 13 0 0 13 13 13 4 Leucine Rich repeat LRR_1 PF00560.33 EGG21105.1 - 0.0034 17.7 24.2 34 5.5 0.3 10.4 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.6 EGG21105.1 - 0.071 12.9 27.8 0.15 11.9 3.8 7.4 6 3 0 7 7 7 0 Leucine rich repeat tRNA_synthFbeta PF17759.1 EGG21107.1 - 5.9e-38 130.5 0.0 1.3e-37 129.3 0.0 1.6 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EGG21107.1 - 1.2e-31 108.7 0.2 1.4e-30 105.3 0.0 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EGG21107.1 - 3.1e-23 82.3 0.1 6.9e-23 81.2 0.1 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EGG21107.1 - 8.2e-18 64.5 0.0 4.6e-16 58.9 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetase B5 domain TIG PF01833.24 EGG21108.1 - 3.1e-37 126.5 149.5 0.00013 22.0 1.2 18.4 16 3 3 19 19 19 14 IPT/TIG domain EGF_2 PF07974.13 EGG21108.1 - 0.0032 17.8 14.4 0.0072 16.7 14.4 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG21108.1 - 0.044 13.8 9.5 0.12 12.5 9.5 1.7 1 0 0 1 1 1 0 Tenascin EGF domain hEGF PF12661.7 EGG21108.1 - 0.085 13.5 9.2 0.36 11.5 9.2 2.2 1 0 0 1 1 1 0 Human growth factor-like EGF I-EGF_1 PF18372.1 EGG21108.1 - 1.7 8.8 7.3 3.8 7.7 7.3 1.6 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Pre-PUA PF17832.1 EGG21109.1 - 5.7e-24 84.6 0.1 1.2e-23 83.6 0.1 1.5 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EGG21109.1 - 8.9e-17 60.8 0.1 1.8e-16 59.8 0.1 1.5 2 0 0 2 2 2 1 PUA domain DUF1947 PF09183.10 EGG21109.1 - 0.071 13.4 0.8 0.18 12.1 0.4 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1947) AAA_16 PF13191.6 EGG21110.1 - 1.9e-31 109.8 0.0 3.4e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.25 EGG21110.1 - 9.5e-20 71.1 1.2 4.9e-19 68.7 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21110.1 - 1e-11 44.6 0.0 3.2e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase AAA_22 PF13401.6 EGG21110.1 - 0.008 16.5 0.0 0.054 13.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EGG21110.1 - 0.0083 16.1 0.0 0.35 10.8 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea DUF2791 PF10923.8 EGG21110.1 - 0.028 13.3 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) ANAPC5 PF12862.7 EGG21110.1 - 0.056 13.5 0.2 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 DUF1878 PF08963.10 EGG21110.1 - 0.29 11.6 3.5 0.84 10.2 3.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) TPR_2 PF07719.17 EGG21110.1 - 1.5 9.1 5.6 8.8 6.7 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Response_reg PF00072.24 EGG21111.1 - 9.7e-26 90.1 0.2 4.4e-24 84.8 0.1 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 EGG21111.1 - 1.3e-24 86.8 2.7 6e-23 81.5 2.8 2.9 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG21111.1 - 2.3e-16 59.6 0.2 2.3e-16 59.6 0.2 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 EGG21111.1 - 2.3e-07 31.5 0.0 8.9e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 EGG21111.1 - 4.3e-06 27.1 0.0 8.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 GAF domain DUF1471 PF07338.13 EGG21112.1 - 0.032 14.2 0.2 3.6 7.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) DUF2717 PF10911.8 EGG21112.1 - 0.093 12.5 0.0 3.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) Ras PF00071.22 EGG21113.1 - 5.8e-46 156.1 0.5 6.5e-46 155.9 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG21113.1 - 1.3e-14 54.4 0.1 1.9e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG21113.1 - 4.5e-10 39.3 0.1 5.1e-10 39.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG21113.1 - 8.3e-07 28.7 0.5 6.1e-06 25.9 0.4 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGG21113.1 - 0.00014 21.8 0.1 0.0047 16.8 0.0 2.2 1 1 1 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EGG21113.1 - 0.001 19.1 0.2 0.0016 18.5 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 EGG21113.1 - 0.01 15.8 0.1 0.018 15.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EGG21113.1 - 0.023 14.1 0.1 0.031 13.7 0.1 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Inhibitor_I29 PF08246.12 EGG21115.1 - 1.1e-09 38.6 7.2 1.1e-09 38.6 7.2 2.4 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) YvbH_ext PF11724.8 EGG21115.1 - 0.92 9.9 8.5 2.9 8.3 0.5 3.5 3 0 0 3 3 3 0 YvbH-like oligomerisation region Endonuclease_5 PF04493.14 EGG21116.1 - 7.6e-60 202.0 0.0 1.3e-59 201.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease V UvrC_HhH_N PF08459.11 EGG21116.1 - 0.0013 18.6 0.0 0.0035 17.3 0.0 1.7 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal SHOCT PF09851.9 EGG21116.1 - 0.089 12.6 0.3 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Short C-terminal domain Utp14 PF04615.13 EGG21116.1 - 1.2 7.7 12.5 1.5 7.3 12.5 1.1 1 0 0 1 1 1 0 Utp14 protein ALMT PF11744.8 EGG21116.1 - 2.5 6.8 5.3 5.9 5.6 5.3 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter RhoGAP PF00620.27 EGG21117.1 - 1.2e-34 119.3 0.6 3.5e-34 117.8 0.6 1.8 1 0 0 1 1 1 1 RhoGAP domain BAR_3 PF16746.5 EGG21117.1 - 2.4e-15 56.9 7.5 4.6e-15 56.0 7.5 1.4 1 0 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 EGG21117.1 - 1e-13 51.5 1.8 1.8e-13 50.7 1.8 1.4 1 0 0 1 1 1 1 BAR domain SUIM_assoc PF16619.5 EGG21117.1 - 0.013 15.5 8.5 0.013 15.5 8.5 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Xol-1_N PF09108.10 EGG21117.1 - 0.065 13.1 0.3 0.16 11.8 0.3 1.6 1 0 0 1 1 1 0 Switch protein XOL-1, N-terminal Phage_GP20 PF06810.11 EGG21117.1 - 1.6 8.5 6.8 2.6 7.9 0.7 2.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 Calreticulin PF00262.18 EGG21118.1 - 2.7e-80 270.0 17.7 6.6e-60 202.9 7.1 3.0 2 1 1 3 3 3 2 Calreticulin family TP53IP5 PF15331.6 EGG21118.1 - 3.8 7.6 10.3 3.9 7.6 8.8 1.7 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 CTD_bind PF04818.13 EGG21119.1 - 4.3e-13 49.9 3.5 6e-13 49.4 0.6 2.6 2 0 0 2 2 2 1 RNA polymerase II-binding domain. BRCT PF00533.26 EGG21119.1 - 1.5e-07 31.7 0.4 2.8e-06 27.6 0.4 2.6 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGG21119.1 - 1.1e-06 29.0 0.2 2.4e-05 24.6 0.2 3.0 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGG21119.1 - 0.00011 22.1 0.1 0.00026 20.9 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain AMP-binding PF00501.28 EGG21120.1 - 6.4e-99 331.4 0.0 8.3e-99 331.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG21120.1 - 0.00016 22.6 0.0 0.00036 21.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 EGG21121.1 - 2.1e-45 151.7 44.1 2.3e-06 28.2 1.4 8.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG21121.1 - 2.9e-19 69.2 9.3 0.017 15.4 0.1 6.8 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG21121.1 - 1.5e-10 40.4 15.9 0.18 10.4 0.3 6.4 4 2 2 6 6 6 6 Nucleoporin Nup120/160 F-box-like PF12937.7 EGG21121.1 - 4e-09 36.2 0.8 1.3e-08 34.6 0.8 1.9 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 EGG21121.1 - 2.8e-07 30.2 0.3 4.2e-05 23.0 0.2 2.8 2 0 0 2 2 2 1 WD40-like domain F-box PF00646.33 EGG21121.1 - 2e-05 24.4 0.9 5.1e-05 23.0 0.9 1.7 1 0 0 1 1 1 1 F-box domain Secretin_N_2 PF07655.13 EGG21121.1 - 0.0028 18.1 5.7 0.0028 18.1 5.7 2.7 2 1 0 2 2 2 1 Secretin N-terminal domain CPSF100_C PF13299.6 EGG21121.1 - 0.31 11.2 2.4 13 6.0 0.9 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Corazonin PF17308.2 EGG21121.1 - 4 7.8 20.0 0.12 12.8 11.5 2.3 2 0 0 2 2 2 0 Pro-corazonin Hydin_ADK PF17213.3 EGG21121.1 - 4.2 7.6 4.9 0.93 9.7 1.0 1.8 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain CBM49 PF09478.10 EGG21122.1 - 2.9e-25 88.4 11.9 2.8e-10 40.4 0.8 3.2 3 0 0 3 3 3 3 Carbohydrate binding domain CBM49 WD40 PF00400.32 EGG21123.1 - 4.6e-21 74.8 20.2 0.00055 20.7 0.0 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG21123.1 - 1.7e-10 41.1 10.4 0.0017 18.6 0.6 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 EGG21124.1 - 1.3e-39 135.6 0.0 3.1e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EGG21124.1 - 1.5e-23 82.6 0.1 5e-23 80.9 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EGG21124.1 - 1e-20 73.5 6.8 1e-20 73.5 6.8 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EGG21124.1 - 1.4e-08 34.4 0.0 4e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGG21124.1 - 2.6e-06 27.3 0.0 4.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EGG21124.1 - 1.8e-05 24.7 0.0 7.4e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGG21124.1 - 3e-05 24.3 0.3 0.046 14.0 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGG21124.1 - 4.3e-05 24.0 0.1 0.00036 20.9 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 EGG21124.1 - 5.4e-05 22.5 0.0 8.6e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 EGG21124.1 - 0.00013 21.3 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EGG21124.1 - 0.00013 21.9 0.0 0.00032 20.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGG21124.1 - 0.00026 21.1 0.1 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EGG21124.1 - 0.00043 20.6 0.0 0.0012 19.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 EGG21124.1 - 0.00093 19.0 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 EGG21124.1 - 0.0011 18.8 0.8 0.0019 17.9 0.1 1.8 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 EGG21124.1 - 0.0011 18.4 0.6 0.23 10.8 0.1 2.5 1 1 1 2 2 2 1 KaiC AAA_33 PF13671.6 EGG21124.1 - 0.0051 17.0 0.1 0.068 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGG21124.1 - 0.0054 17.3 0.0 0.019 15.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain Tma16 PF11176.8 EGG21124.1 - 0.011 15.6 0.9 0.021 14.7 0.9 1.5 1 0 0 1 1 1 0 Translation machinery-associated protein 16 NACHT PF05729.12 EGG21124.1 - 0.013 15.5 0.0 0.59 10.0 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Use1 PF09753.9 EGG21124.1 - 0.019 14.7 3.0 0.055 13.2 2.1 2.0 2 0 0 2 2 2 0 Membrane fusion protein Use1 AAA_25 PF13481.6 EGG21124.1 - 0.021 14.4 0.5 0.22 11.1 0.1 2.4 2 1 1 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 EGG21124.1 - 0.022 14.5 0.1 0.05 13.3 0.0 1.6 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase TniB PF05621.11 EGG21124.1 - 0.024 14.0 0.4 2.5 7.5 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein Mg_chelatase PF01078.21 EGG21124.1 - 0.026 13.9 0.0 0.065 12.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 EGG21124.1 - 0.04 13.0 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 EGG21124.1 - 0.042 13.4 0.1 0.2 11.2 0.1 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 EGG21124.1 - 0.048 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGG21124.1 - 0.057 12.7 0.2 0.88 8.8 0.0 2.4 1 1 1 2 2 2 0 Zeta toxin Torsin PF06309.11 EGG21124.1 - 0.06 13.5 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 1 0 Torsin DUF2075 PF09848.9 EGG21124.1 - 0.079 12.2 0.3 0.58 9.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EGG21124.1 - 0.086 12.3 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 EGG21124.1 - 0.098 13.2 0.2 0.95 10.0 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 EGG21124.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AKAP7_RIRII_bdg PF10470.9 EGG21124.1 - 0.14 12.3 0.3 0.42 10.7 0.3 1.8 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Zot PF05707.12 EGG21124.1 - 0.17 11.5 0.3 2.8 7.6 0.0 2.2 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) Sigma54_activat PF00158.26 EGG21124.1 - 0.17 11.6 0.0 1 9.1 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain CSF-1 PF05337.11 EGG21124.1 - 0.18 11.9 0.4 0.38 10.9 0.4 1.4 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) ATPase_2 PF01637.18 EGG21124.1 - 0.2 11.5 4.4 2.4 8.0 0.0 2.8 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea Neurochondrin PF05536.11 EGG21125.1 - 1.7e-14 53.1 1.4 5.6e-09 34.9 0.0 2.8 2 1 0 2 2 2 2 Neurochondrin CK_II_beta PF01214.18 EGG21125.1 - 0.92 9.3 4.1 2.5 7.9 4.1 1.7 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Arm PF00514.23 EGG21126.1 - 5.9e-15 54.7 3.3 0.0005 20.0 0.0 5.4 6 0 0 6 6 5 3 Armadillo/beta-catenin-like repeat FYVE PF01363.21 EGG21126.1 - 6.4e-15 55.0 15.5 1.7e-14 53.7 15.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger SR-25 PF10500.9 EGG21126.1 - 0.00022 20.9 19.2 0.00034 20.3 19.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Baculo_PP31 PF05311.11 EGG21126.1 - 0.0013 18.3 7.2 0.0022 17.6 7.2 1.3 1 0 0 1 1 1 1 Baculovirus 33KDa late protein (PP31) Connexin PF00029.19 EGG21126.1 - 0.0025 17.6 2.0 0.0041 16.9 2.0 1.3 1 0 0 1 1 1 1 Connexin Vac14_Fab1_bd PF12755.7 EGG21126.1 - 0.0047 17.5 0.4 0.05 14.2 0.0 2.7 2 1 0 2 2 2 1 Vacuolar 14 Fab1-binding region Eapp_C PF10238.9 EGG21126.1 - 0.0072 16.4 0.3 0.0072 16.4 0.3 1.9 2 0 0 2 2 1 1 E2F-associated phosphoprotein STAG PF08514.11 EGG21126.1 - 0.025 14.5 0.3 0.025 14.5 0.3 3.6 3 1 0 3 3 1 0 STAG domain NARP1 PF12569.8 EGG21126.1 - 0.03 13.3 12.9 0.046 12.6 12.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.12 EGG21126.1 - 0.039 14.2 5.0 0.063 13.6 5.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.17 EGG21126.1 - 0.055 13.6 1.1 0.087 13.0 0.3 1.7 2 0 0 2 2 2 0 DDHD domain AP3D1 PF06375.11 EGG21126.1 - 0.093 13.0 15.8 0.17 12.1 15.8 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 EIIBC-GUT_N PF03612.14 EGG21126.1 - 0.11 12.2 4.0 0.19 11.5 4.0 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF1003 PF06210.11 EGG21126.1 - 0.12 12.4 0.4 0.3 11.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) CTNNB1_binding PF08347.11 EGG21126.1 - 0.13 12.4 0.2 0.25 11.5 0.2 1.4 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Afi1 PF07792.12 EGG21126.1 - 0.17 12.3 2.4 0.33 11.4 2.4 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RPN2_C PF18004.1 EGG21126.1 - 0.24 11.3 16.1 0.4 10.6 16.1 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain HA2 PF04408.23 EGG21126.1 - 0.49 10.7 3.3 1.8 8.9 3.3 2.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) CDC45 PF02724.14 EGG21126.1 - 0.54 8.5 7.7 0.73 8.0 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Tau95_N PF17682.1 EGG21126.1 - 0.72 10.1 6.1 0.95 9.7 5.1 1.8 2 0 0 2 2 1 0 Tau95 Triple barrel domain RR_TM4-6 PF06459.12 EGG21126.1 - 1.1 9.0 12.5 1.7 8.4 12.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPL5 PF18168.1 EGG21126.1 - 1.7 7.8 7.6 3.2 7.0 7.6 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S49_N PF08496.10 EGG21126.1 - 1.8 8.7 12.4 3.6 7.7 12.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Nop53 PF07767.11 EGG21126.1 - 1.8 7.8 24.0 2.6 7.3 24.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) AIF_C PF14721.6 EGG21126.1 - 1.9 8.8 4.9 3.5 8.0 4.9 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2828 PF11443.8 EGG21126.1 - 2.4 6.2 10.6 3.6 5.5 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3464 PF11947.8 EGG21126.1 - 6 6.6 11.5 10 5.9 11.5 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 FAM199X PF15814.5 EGG21126.1 - 7.4 5.5 9.6 12 4.8 9.6 1.2 1 0 0 1 1 1 0 Protein family FAM199X ArfGap PF01412.18 EGG21127.1 - 1.1e-39 135.1 0.6 1.1e-39 135.1 0.6 2.9 3 0 0 3 3 2 1 Putative GTPase activating protein for Arf PH PF00169.29 EGG21127.1 - 6e-19 68.5 11.2 1.1e-12 48.4 0.1 3.6 3 1 1 4 4 3 2 PH domain PH_11 PF15413.6 EGG21127.1 - 7.5e-05 23.1 1.0 7.5e-05 23.1 1.0 3.6 3 2 0 3 3 2 1 Pleckstrin homology domain RR_TM4-6 PF06459.12 EGG21127.1 - 0.11 12.4 19.5 0.27 11.0 19.5 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 VIR_N PF15912.5 EGG21127.1 - 0.18 11.4 13.2 0.53 9.8 13.2 1.8 1 0 0 1 1 1 0 Virilizer, N-terminal NARP1 PF12569.8 EGG21127.1 - 0.36 9.7 21.8 0.62 8.9 21.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SpoIIP PF07454.11 EGG21127.1 - 0.36 10.2 13.1 0.83 9.1 13.1 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Cellulose_synt PF03552.14 EGG21127.1 - 0.71 8.3 3.6 1 7.8 3.6 1.1 1 0 0 1 1 1 0 Cellulose synthase Vfa1 PF08432.10 EGG21127.1 - 0.82 10.0 23.7 3.1 8.1 23.7 2.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 EGG21127.1 - 1.1 7.5 20.9 1.9 6.7 20.9 1.3 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 EGG21127.1 - 1.2 8.3 9.2 2 7.5 9.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.14 EGG21127.1 - 1.7 9.1 18.7 1.5 9.3 13.4 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 AAA_23 PF13476.6 EGG21127.1 - 2.8 8.4 20.1 2.1 8.8 14.2 2.8 3 0 0 3 3 2 0 AAA domain Trypan_PARP PF05887.11 EGG21127.1 - 2.8 7.9 16.6 0.081 12.9 9.7 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF913 PF06025.12 EGG21127.1 - 4.6 6.1 10.6 10 5.0 10.6 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF5427 PF10310.9 EGG21127.1 - 4.9 6.0 19.0 11 4.8 19.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLC12 PF03522.15 EGG21127.1 - 5.3 6.0 13.1 11 5.0 13.1 1.4 1 0 0 1 1 1 0 Solute carrier family 12 GAGA_bind PF06217.12 EGG21127.1 - 6.8 6.9 14.0 48 4.1 13.1 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family Zip PF02535.22 EGG21127.1 - 7.7 5.6 12.3 16 4.6 12.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 EGG21127.1 - 8.2 5.1 19.1 20 3.8 19.1 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CPSF100_C PF13299.6 EGG21127.1 - 9 6.4 16.1 4.3 7.5 13.1 2.0 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal Paramyxo_ncap PF00973.19 EGG21127.1 - 9.5 5.0 9.4 15 4.4 9.4 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RAB3GAP2_C PF14656.6 EGG21127.1 - 9.8 4.3 9.8 16 3.6 9.8 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus UPF0139 PF03669.13 EGG21128.1 - 1.1e-31 108.6 0.4 1.2e-31 108.4 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) YtpI PF14007.6 EGG21128.1 - 0.096 12.8 0.8 0.13 12.4 0.2 1.5 1 1 0 1 1 1 0 YtpI-like protein DUF3040 PF11239.8 EGG21128.1 - 0.21 11.9 1.9 4.7 7.6 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) DUF202 PF02656.15 EGG21130.1 - 0.085 13.3 0.6 0.4 11.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Peptidase_C1 PF00112.23 EGG21131.1 - 2.1e-43 149.0 0.8 3.7e-43 148.1 0.8 1.4 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.26 EGG21131.1 - 2.7e-10 41.2 1.8 2.7e-10 41.2 1.8 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Peptidase_M73 PF12389.8 EGG21131.1 - 0.085 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase SH3_6 PF12913.7 EGG21131.1 - 0.71 9.5 2.9 4.3 7.0 0.0 2.8 3 0 0 3 3 3 0 SH3 domain (SH3b1 type) DUF647 PF04884.14 EGG21132.1 - 2.4e-79 266.4 1.8 2.4e-79 266.4 1.8 1.8 2 0 0 2 2 2 1 Vitamin B6 photo-protection and homoeostasis Brix PF04427.18 EGG21132.1 - 0.0043 17.2 0.3 0.011 15.9 0.3 1.7 1 0 0 1 1 1 1 Brix domain Replicase PF03090.17 EGG21132.1 - 0.06 13.2 0.9 0.65 9.8 0.0 2.3 2 0 0 2 2 2 0 Replicase family HMG_box PF00505.19 EGG21133.1 - 1.3e-05 25.5 8.1 1.3e-05 25.5 8.1 2.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGG21133.1 - 6e-05 23.5 3.1 6e-05 23.5 3.1 3.9 4 0 0 4 4 4 1 HMG-box domain IBR PF01485.21 EGG21134.1 - 3.5e-19 68.8 23.9 7.6e-11 42.1 10.5 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EGG21134.1 - 0.00081 19.2 6.4 0.00081 19.2 6.4 4.8 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG21134.1 - 0.013 15.3 39.5 0.041 13.8 9.3 4.4 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGG21134.1 - 0.028 14.2 3.5 0.11 12.3 3.5 2.1 1 0 0 1 1 1 0 RING-like zinc finger CH_2 PF06294.11 EGG21134.1 - 0.18 11.9 1.2 2.8 8.1 0.1 2.6 2 0 0 2 2 2 0 CH-like domain in sperm protein zf-RING_14 PF17978.1 EGG21134.1 - 4 7.9 10.1 0.14 12.6 2.2 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain G-patch PF01585.23 EGG21135.1 - 1.4e-14 53.7 1.6 2.8e-14 52.7 1.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGG21135.1 - 2e-05 24.6 0.5 2e-05 24.6 0.5 3.9 4 1 0 4 4 4 1 G-patch domain SR-25 PF10500.9 EGG21136.1 - 0.11 12.1 15.1 0.15 11.6 15.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Orf78 PF06024.12 EGG21136.1 - 0.32 11.3 2.9 0.7 10.2 2.8 1.8 1 1 0 1 1 1 0 Orf78 (ac78) KR PF08659.10 EGG21137.1 - 1.7e-24 86.8 0.1 2.4e-24 86.2 0.1 1.3 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 EGG21137.1 - 1.2e-06 28.8 0.1 3.5e-06 27.3 0.1 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Kinesin PF00225.23 EGG21138.1 - 2.3e-103 345.6 0.0 4.8e-103 344.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGG21138.1 - 3e-21 75.9 0.1 1.7e-20 73.5 0.0 2.4 3 0 0 3 3 3 1 Microtubule binding ATG16 PF08614.11 EGG21138.1 - 0.001 19.3 0.8 0.001 19.3 0.8 3.6 2 1 0 3 3 3 1 Autophagy protein 16 (ATG16) CEP63 PF17045.5 EGG21138.1 - 0.0015 18.5 1.9 0.0015 18.5 1.9 2.2 2 0 0 2 2 2 1 Centrosomal protein of 63 kDa PKcGMP_CC PF16808.5 EGG21138.1 - 0.009 15.8 1.1 0.009 15.8 1.1 4.5 4 0 0 4 4 4 1 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_1 PF00170.21 EGG21138.1 - 0.02 15.0 0.7 0.02 15.0 0.7 3.9 5 0 0 5 5 4 0 bZIP transcription factor Rootletin PF15035.6 EGG21138.1 - 0.041 13.9 6.0 0.72 9.9 1.2 2.4 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Nup54 PF13874.6 EGG21138.1 - 0.23 11.6 1.8 1.6 8.8 0.2 2.4 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Hrs_helical PF12210.8 EGG21138.1 - 0.36 11.4 2.6 7 7.3 0.0 2.5 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Fez1 PF06818.15 EGG21138.1 - 0.46 10.9 13.6 0.42 11.1 0.6 2.5 2 1 0 2 2 2 0 Fez1 Pox_A_type_inc PF04508.12 EGG21138.1 - 1.2 9.2 10.0 0.2 11.6 0.2 3.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF4407 PF14362.6 EGG21138.1 - 2.8 7.2 9.4 1.1e+02 2.0 9.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4472 PF14739.6 EGG21138.1 - 3.1 8.6 17.1 1.4 9.7 0.8 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4472) ZapB PF06005.12 EGG21138.1 - 3.4 8.2 20.6 2.8 8.4 4.7 3.6 2 2 1 3 3 3 0 Cell division protein ZapB DUF1664 PF07889.12 EGG21138.1 - 3.9 7.5 14.3 0.3 11.1 1.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 EGG21138.1 - 4.5 7.4 8.1 5.1 7.2 2.1 3.2 3 1 0 3 3 2 0 TolA binding protein trimerisation GIT_CC PF16559.5 EGG21138.1 - 5 7.1 7.8 1 9.2 0.1 3.3 4 0 0 4 4 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 EGG21138.1 - 5.4 7.2 27.4 0.28 11.4 2.7 4.6 4 2 1 5 5 5 0 Centrosomin N-terminal motif 1 Spc29 PF17082.5 EGG21138.1 - 7.8 6.3 11.0 2.8 7.7 0.1 3.0 2 1 0 2 2 2 0 Spindle Pole Component 29 Exo84_C PF16528.5 EGG21138.1 - 9.4 6.0 8.7 5 6.9 3.6 2.6 2 1 0 2 2 2 0 Exocyst component 84 C-terminal Arb2 PF09757.9 EGG21139.1 - 3.1e-05 23.2 0.9 0.00011 21.4 0.0 2.0 2 0 0 2 2 2 1 Arb2 domain Peptidase_S9 PF00326.21 EGG21139.1 - 0.0094 15.4 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Antigen_Bd37 PF11641.8 EGG21139.1 - 0.018 14.5 0.4 0.043 13.3 0.4 1.5 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein DUF900 PF05990.12 EGG21139.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 EGG21139.1 - 0.02 14.5 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EGG21139.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase ECH_1 PF00378.20 EGG21140.1 - 7.6e-59 199.0 0.0 8.8e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGG21140.1 - 4.4e-43 148.1 0.5 4e-36 125.2 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Redoxin PF08534.10 EGG21141.1 - 1.9e-30 105.5 0.1 2.1e-30 105.4 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGG21141.1 - 7.3e-09 35.6 0.0 8.8e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family PBSX_XtrA PF17356.2 EGG21141.1 - 0.066 13.1 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Phage-like element PBSX protein XtrA RasGEF PF00617.19 EGG21142.1 - 1.2e-58 198.2 0.6 3e-58 196.9 0.2 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGG21142.1 - 2.7e-20 72.6 3.6 4.5e-20 71.8 1.3 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif Myb_DNA-binding PF00249.31 EGG21144.1 - 8e-34 115.6 12.9 2.5e-15 56.4 0.5 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG21144.1 - 7.4e-26 90.2 17.1 5.3e-15 55.4 0.7 4.5 3 2 1 4 4 4 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGG21144.1 - 0.00055 20.1 7.1 0.89 9.8 0.1 3.8 1 1 2 3 3 3 3 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EGG21144.1 - 0.0016 18.4 11.5 0.15 12.1 0.1 4.0 3 1 1 4 4 4 2 SLIDE Myb_DNA-bind_7 PF15963.5 EGG21144.1 - 0.25 11.3 9.0 2.3 8.2 0.2 3.4 2 1 1 3 3 3 0 Myb DNA-binding like DUF2718 PF10918.8 EGG21144.1 - 9.7 6.7 11.2 8.1 7.0 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) PIP5K PF01504.18 EGG21146.1 - 0.01 15.1 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase GerE PF00196.19 EGG21146.1 - 0.012 15.1 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_24 PF13412.6 EGG21146.1 - 0.035 13.7 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 EGG21146.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 F-box-like PF12937.7 EGG21146.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 F-box-like HTH_10 PF04967.12 EGG21146.1 - 0.17 11.7 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 HTH DNA binding domain Mito_carr PF00153.27 EGG21147.1 - 2.7e-71 235.6 4.6 8.6e-24 83.3 0.1 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Aph-1 PF06105.12 EGG21148.1 - 1e-72 244.3 15.1 1.2e-72 244.1 15.1 1.0 1 0 0 1 1 1 1 Aph-1 protein YhfC PF10086.9 EGG21148.1 - 0.037 13.4 0.7 0.037 13.4 0.7 1.9 2 0 0 2 2 2 0 YhfC intramembrane metalloprotease CPP1-like PF11833.8 EGG21148.1 - 0.056 13.1 0.2 0.056 13.1 0.2 1.7 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2721 PF11026.8 EGG21148.1 - 0.09 12.7 0.0 0.09 12.7 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) Cyt-b5 PF00173.28 EGG21149.1 - 7.6e-19 67.6 0.2 1.1e-18 67.2 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ank_2 PF12796.7 EGG21150.1 - 1.4e-31 108.9 6.2 5.6e-14 52.5 0.6 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG21150.1 - 4.4e-26 90.9 0.3 2.6e-08 34.2 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG21150.1 - 3.6e-19 68.6 12.9 6.9e-06 26.2 0.0 5.9 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG21150.1 - 1.1e-18 65.4 2.9 0.00053 20.2 0.1 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 EGG21150.1 - 1.1e-13 50.9 4.4 8.5e-05 22.8 0.3 6.7 6 0 0 6 6 6 3 Ankyrin repeat SIKE PF05769.11 EGG21151.1 - 4.1e-05 23.6 24.4 0.00024 21.1 24.4 2.2 1 1 0 1 1 1 1 SIKE family ABC_tran_CTD PF16326.5 EGG21151.1 - 0.0013 18.9 1.0 0.0013 18.9 1.0 3.8 2 2 2 4 4 4 1 ABC transporter C-terminal domain DUF1350 PF07082.11 EGG21151.1 - 0.03 13.6 0.1 0.03 13.6 0.1 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1350) TSC22 PF01166.18 EGG21151.1 - 0.35 11.2 19.2 1.5 9.2 0.8 4.7 4 1 0 4 4 4 0 TSC-22/dip/bun family bZIP_1 PF00170.21 EGG21151.1 - 0.63 10.2 19.0 0.23 11.6 0.6 4.0 4 0 0 4 4 4 0 bZIP transcription factor Phage_lysozyme PF00959.19 EGG21151.1 - 1.2 9.7 7.5 1.1 9.8 0.2 2.7 3 0 0 3 3 3 0 Phage lysozyme HD_assoc PF13286.6 EGG21151.1 - 1.3 9.6 5.9 4.5 7.9 0.2 2.5 2 1 0 2 2 2 0 Phosphohydrolase-associated domain YabA PF06156.13 EGG21151.1 - 7.3 7.3 32.4 2.5 8.8 2.0 4.1 1 1 2 3 3 3 0 Initiation control protein YabA EF-hand_1 PF00036.32 EGG21152.1 - 1e-19 68.5 6.3 4.8e-07 28.9 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 EGG21152.1 - 3.2e-19 67.5 4.3 3.5e-07 29.4 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGG21152.1 - 1.3e-16 59.1 2.6 0.00022 20.9 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EGG21152.1 - 3e-15 56.4 2.8 7.5e-10 39.1 0.3 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGG21152.1 - 3.5e-10 39.6 5.7 0.015 15.1 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGG21152.1 - 1.9e-05 25.0 0.4 0.49 10.7 0.0 3.2 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EGG21152.1 - 0.0019 18.3 3.2 0.33 11.2 0.9 2.8 1 1 2 3 3 3 2 Dockerin type I domain EF-hand_4 PF12763.7 EGG21152.1 - 0.0068 16.4 1.9 0.19 11.7 0.1 2.6 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand RNase_HII PF01351.18 EGG21153.1 - 8.6e-47 159.5 0.0 1.2e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII AA_permease_2 PF13520.6 EGG21154.1 - 2.3e-22 79.5 55.9 3.1e-22 79.0 55.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGG21154.1 - 7.1e-22 77.6 52.8 9.3e-22 77.2 52.8 1.0 1 0 0 1 1 1 1 Amino acid permease Val_tRNA-synt_C PF10458.9 EGG21154.1 - 0.037 14.3 0.2 0.059 13.7 0.2 1.2 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm UXS1_N PF11803.8 EGG21154.1 - 0.041 14.3 0.0 0.18 12.2 0.0 2.1 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal LUC7 PF03194.15 EGG21155.1 - 2.2e-63 214.3 17.8 2.2e-63 214.3 17.8 4.6 5 1 0 5 5 5 1 LUC7 N_terminus TPR_8 PF13181.6 EGG21155.1 - 0.0068 16.5 0.1 0.0068 16.5 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG21155.1 - 0.017 15.4 3.9 0.15 12.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG21155.1 - 0.041 14.0 9.9 0.73 10.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGG21155.1 - 0.11 13.1 8.9 1.8 9.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat adh_short PF00106.25 EGG21156.1 - 1.9e-43 148.2 0.0 2.6e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG21156.1 - 3.8e-24 85.5 0.0 4.8e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG21156.1 - 1.3e-13 51.3 0.1 3.9e-13 49.7 0.1 1.7 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EGG21156.1 - 3.6e-05 24.0 0.1 6.2e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EGG21156.1 - 0.0013 18.2 0.1 0.012 15.1 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGG21156.1 - 0.012 14.8 0.2 0.02 14.0 0.2 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1761 PF08570.10 EGG21156.1 - 0.052 13.8 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) NAD_binding_10 PF13460.6 EGG21156.1 - 0.067 13.1 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 EGG21156.1 - 0.068 13.6 0.0 0.94 9.9 0.0 2.5 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain BAF250_C PF12031.8 EGG21156.1 - 0.088 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa Lactamase_B_6 PF16661.5 EGG21157.1 - 2e-16 60.0 2.0 2.8e-15 56.3 1.4 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EGG21157.1 - 4.9e-10 39.0 2.8 9.5e-08 31.5 2.1 2.8 2 1 0 2 2 2 2 Putative beta-lactamase-like family Peptidase_M24 PF00557.24 EGG21158.1 - 8.9e-57 192.2 0.0 1.3e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGG21158.1 - 9.6e-35 119.0 0.0 2.8e-34 117.5 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Aldolase_II PF00596.21 EGG21159.1 - 1.1e-39 136.3 0.2 1.4e-39 136.0 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Lung_7-TM_R PF06814.13 EGG21160.1 - 1.6e-57 195.0 28.0 2.5e-57 194.4 28.0 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor Vma12 PF11712.8 EGG21160.1 - 1.6 8.8 4.2 3.6 7.7 4.2 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase LSM PF01423.22 EGG21161.1 - 4e-20 71.3 0.6 5.6e-20 70.8 0.6 1.2 1 0 0 1 1 1 1 LSM domain HydF_dimer PF18128.1 EGG21161.1 - 0.048 13.7 0.4 0.13 12.3 0.2 1.7 1 1 1 2 2 2 0 Hydrogen maturase F dimerization domain DUF2678 PF10856.8 EGG21162.1 - 5.6e-08 32.7 1.7 8.2e-08 32.2 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) DUF2070 PF09843.9 EGG21162.1 - 0.018 13.3 3.7 0.022 13.1 3.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2427 PF10348.9 EGG21162.1 - 0.13 12.1 1.5 0.2 11.5 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF805 PF05656.14 EGG21162.1 - 1.2 9.6 7.3 2.1 8.8 7.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DZR PF12773.7 EGG21163.1 - 0.021 14.8 0.9 0.034 14.2 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.18 EGG21163.1 - 0.028 13.7 1.4 0.055 12.8 1.4 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zinc_ribbon_2 PF13240.6 EGG21163.1 - 0.042 13.6 4.1 0.092 12.5 4.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EGG21163.1 - 2.1 7.9 5.4 4.6 6.8 5.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-NADH-PPase PF09297.11 EGG21163.1 - 4.7 7.0 5.9 10 5.9 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Sel1 PF08238.12 EGG21164.1 - 2.7e-25 88.2 7.6 4.3e-08 33.6 0.5 6.0 6 0 0 6 6 6 5 Sel1 repeat RRM_1 PF00076.22 EGG21165.1 - 0.019 14.8 0.2 0.23 11.3 0.2 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Coatamer_beta_C PF07718.12 EGG21166.1 - 0.00086 19.2 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Adaptin_N PF01602.20 EGG21166.1 - 0.0015 17.1 0.4 0.0027 16.4 0.4 1.3 1 0 0 1 1 1 1 Adaptin N terminal region SPX PF03105.19 EGG21166.1 - 0.44 10.4 9.8 0.21 11.5 7.8 1.5 2 0 0 2 2 2 0 SPX domain Miga PF10265.9 EGG21166.1 - 7.8 5.3 10.5 14 4.5 10.5 1.3 1 0 0 1 1 1 0 Mitoguardin MinC_C PF03775.16 EGG21167.1 - 0.15 12.1 0.1 0.62 10.1 0.1 2.1 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain Pkr1 PF08636.10 EGG21169.1 - 3.3e-05 24.0 1.2 5.6e-05 23.2 1.2 1.3 1 0 0 1 1 1 1 ER protein Pkr1 DUF2207 PF09972.9 EGG21169.1 - 0.0069 15.2 0.3 0.012 14.4 0.3 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) CPP1-like PF11833.8 EGG21169.1 - 0.046 13.4 0.1 0.046 13.4 0.1 2.3 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like VIT1 PF01988.19 EGG21169.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 VIT family CbiQ PF02361.16 EGG21169.1 - 0.12 12.0 1.0 0.18 11.4 1.0 1.2 1 0 0 1 1 1 0 Cobalt transport protein Membralin PF09746.9 EGG21169.1 - 0.14 11.2 0.9 0.23 10.5 0.9 1.4 1 0 0 1 1 1 0 Tumour-associated protein EMC3_TMCO1 PF01956.16 EGG21169.1 - 2.3 7.9 5.8 6.4 6.5 5.8 1.8 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like UPF0242 PF06785.11 EGG21169.1 - 2.7 8.0 18.9 0.79 9.8 10.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 EGG21169.1 - 3.8 6.3 10.2 11 4.8 10.2 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein vATP-synt_AC39 PF01992.16 EGG21170.1 - 5.4e-120 400.9 2.5 6.1e-120 400.7 2.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit CH PF00307.31 EGG21171.1 - 4.9e-13 49.2 0.2 4.9e-13 49.2 0.2 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain ABC_membrane PF00664.23 EGG21172.1 - 4.2e-71 239.8 28.4 8e-42 143.8 14.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGG21172.1 - 4.9e-49 166.4 0.3 6.6e-29 101.2 0.1 3.0 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGG21172.1 - 3.8e-08 33.0 5.6 0.17 11.3 0.1 4.5 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGG21172.1 - 3.3e-05 24.0 0.3 0.15 12.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EGG21172.1 - 6.1e-05 22.7 0.6 0.3 10.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG21172.1 - 8.7e-05 23.0 0.1 0.47 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EGG21172.1 - 0.0015 17.8 0.4 0.1 11.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_15 PF13175.6 EGG21172.1 - 0.0018 18.1 0.0 0.27 10.9 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EGG21172.1 - 0.0021 17.3 0.3 2.1 7.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 EGG21172.1 - 0.0031 16.5 0.3 0.77 8.6 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_21 PF13304.6 EGG21172.1 - 0.0031 17.4 0.5 4.3 7.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGG21172.1 - 0.0041 17.0 2.0 0.49 10.3 0.3 2.5 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 EGG21172.1 - 0.0055 16.8 1.7 0.11 12.6 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 EGG21172.1 - 0.0074 16.8 3.6 2.6 8.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EGG21172.1 - 0.013 15.8 2.2 2.4 8.5 0.2 3.2 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGG21172.1 - 0.026 14.6 2.4 0.6 10.2 0.2 2.6 2 0 0 2 2 2 0 Dynamin family AAA_7 PF12775.7 EGG21172.1 - 0.034 13.7 0.2 3.2 7.2 0.1 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 EGG21172.1 - 0.036 13.1 0.1 4.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 EGG21172.1 - 0.038 14.2 0.4 22 5.3 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EGG21172.1 - 0.061 13.1 0.1 0.45 10.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 EGG21172.1 - 0.066 12.9 0.1 7.6 6.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EGG21172.1 - 0.067 13.0 0.6 0.91 9.3 0.3 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 EGG21172.1 - 0.13 12.7 0.1 22 5.5 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EGG21172.1 - 0.19 11.3 0.6 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 EGG21172.1 - 1.1 8.5 3.7 7.9 5.8 0.2 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family RCC1 PF00415.18 EGG21173.1 - 7.9e-83 272.9 20.5 1.7e-14 54.2 1.0 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG21173.1 - 3.2e-40 135.2 31.1 1.3e-07 31.3 0.2 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EGG21173.1 - 3.5e-29 101.3 3.8 1.3e-14 54.3 0.2 3.4 3 0 0 3 3 3 3 BTB/POZ domain DUF4213 PF13938.6 EGG21173.1 - 0.061 13.6 0.3 29 5.0 0.0 3.6 4 0 0 4 4 4 0 Putative heavy-metal chelation DUF3381 PF11861.8 EGG21173.1 - 0.27 11.0 1.2 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) PI3_PI4_kinase PF00454.27 EGG21174.1 - 1.8e-49 168.9 0.9 6.2e-49 167.1 0.1 2.5 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 EGG21174.1 - 2.3e-28 99.0 9.5 2.1e-26 92.5 9.5 2.9 1 1 0 1 1 1 1 Serine/threonine-protein kinase smg-1 FATC PF02260.20 EGG21174.1 - 3.4e-12 46.0 0.0 1.2e-11 44.2 0.0 2.0 1 0 0 1 1 1 1 FATC domain RLL PF10036.9 EGG21175.1 - 9.9e-63 212.4 6.1 1.3e-62 212.0 6.1 1.2 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein PIP5K PF01504.18 EGG21176.1 - 9.4e-95 316.9 0.1 9.4e-95 316.9 0.1 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Dicty_REP PF05086.12 EGG21176.1 - 0.03 12.3 13.2 0.041 11.9 13.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 EGG21176.1 - 0.091 12.7 13.2 0.17 11.8 13.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGG21176.1 - 0.77 9.7 23.9 1.5 8.8 23.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Tir_receptor_C PF07489.11 EGG21176.1 - 4.3 7.3 13.8 10 6.1 13.8 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus STAG PF08514.11 EGG21177.1 - 6.8e-16 58.2 0.3 6.8e-16 58.2 0.3 6.1 8 0 0 8 8 8 1 STAG domain HEAT PF02985.22 EGG21177.1 - 0.00026 21.0 0.0 3.7 8.1 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 EGG21177.1 - 0.0052 16.8 3.1 0.016 15.3 0.3 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGG21177.1 - 0.12 12.7 0.0 0.67 10.4 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats BRCT_2 PF16589.5 EGG21178.1 - 2.3e-34 117.7 2.9 2.3e-11 44.0 0.0 3.6 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG21178.1 - 1.6e-24 86.1 2.9 4.7e-08 33.3 0.0 4.4 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGG21178.1 - 9.3e-12 45.1 3.3 0.0018 18.5 0.0 4.7 4 1 0 4 4 4 3 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 EGG21178.1 - 1.1e-08 34.9 2.1 0.0017 18.2 0.1 4.3 4 1 0 4 4 4 2 twin BRCT domain BRCT_3 PF18428.1 EGG21178.1 - 6.3e-06 26.2 0.2 0.002 18.1 0.0 3.5 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EGG21178.1 - 0.002 18.0 0.7 2.8 7.9 0.0 3.9 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain RhoGAP PF00620.27 EGG21179.1 - 5.7e-35 120.4 0.2 3.4e-34 117.9 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain zf-MYND PF01753.18 EGG21179.1 - 1.2e-09 38.1 4.7 2e-09 37.4 4.7 1.4 1 0 0 1 1 1 1 MYND finger ALAD PF00490.21 EGG21180.1 - 4e-126 420.5 0.0 4.4e-126 420.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Coiled PF05710.12 EGG21181.1 - 4.1e-15 56.4 17.3 6.1e-15 55.8 17.3 1.3 1 0 0 1 1 1 1 Coiled coil C2 PF00168.30 EGG21182.1 - 2.3e-09 37.5 1.2 8e-07 29.3 0.3 3.1 2 1 0 2 2 2 1 C2 domain Membr_traf_MHD PF10540.9 EGG21182.1 - 1.1e-06 28.9 4.5 0.0054 16.9 0.0 4.1 3 1 1 4 4 4 2 Munc13 (mammalian uncoordinated) homology domain GRAM PF02893.20 EGG21182.1 - 6.1e-05 22.9 9.5 0.016 15.1 0.8 3.8 3 0 0 3 3 3 2 GRAM domain FAM176 PF14851.6 EGG21182.1 - 0.008 15.9 2.2 0.023 14.3 2.2 1.7 1 0 0 1 1 1 1 FAM176 family Ribosomal_60s PF00428.19 EGG21182.1 - 0.12 13.0 7.5 0.32 11.6 7.5 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4530 PF15039.6 EGG21182.1 - 1.3 9.2 9.4 3.5 7.8 9.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) RNA_pol_3_Rpc31 PF11705.8 EGG21182.1 - 1.9 8.7 12.2 4 7.6 12.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 EGG21182.1 - 8.8 6.8 9.5 19 5.7 8.3 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain adh_short PF00106.25 EGG21183.1 - 5.4e-10 39.1 4.7 0.00058 19.4 3.4 3.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG21183.1 - 0.011 15.4 0.9 0.64 9.5 0.3 3.0 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Prenylcys_lyase PF07156.14 EGG21184.1 - 4.9e-74 249.6 0.3 7.7e-74 249.0 0.3 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase DAD PF02109.16 EGG21184.1 - 2.7e-30 104.9 4.9 2.4e-29 101.9 3.0 2.4 2 0 0 2 2 2 1 DAD family Amino_oxidase PF01593.24 EGG21184.1 - 1.1e-18 67.8 0.0 1.7e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGG21184.1 - 2.7e-15 56.3 0.0 5.2e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG21184.1 - 1.2e-07 31.3 0.2 0.0025 17.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG21184.1 - 4.5e-07 30.0 0.3 0.038 14.0 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 EGG21184.1 - 4.2e-06 26.6 0.2 8.8e-06 25.5 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGG21184.1 - 0.0092 14.9 0.5 0.024 13.5 0.4 1.8 2 0 0 2 2 2 1 Tryptophan halogenase DUF3215 PF11503.8 EGG21184.1 - 0.094 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) MCRA PF06100.11 EGG21184.1 - 0.099 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 MCRA family Thi4 PF01946.17 EGG21184.1 - 0.13 11.5 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family 7TMR-DISM_7TM PF07695.11 EGG21184.1 - 0.14 12.1 5.2 0.23 11.3 5.2 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling Pyr_redox_3 PF13738.6 EGG21184.1 - 0.53 9.5 4.8 0.75 9.0 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IBN_N PF03810.19 EGG21185.1 - 2.7e-12 46.4 2.2 1e-11 44.6 0.4 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 EGG21185.1 - 0.036 12.9 0.0 0.13 11.0 0.0 1.9 1 0 0 1 1 1 0 Cse1 Urb2 PF10441.9 EGG21185.1 - 0.054 13.4 0.1 0.87 9.5 0.0 2.6 2 0 0 2 2 2 0 Urb2/Npa2 family HEAT_EZ PF13513.6 EGG21185.1 - 0.7 10.5 4.7 71 4.1 0.4 4.3 4 1 0 4 4 4 0 HEAT-like repeat CbiQ PF02361.16 EGG21186.1 - 0.028 14.1 13.4 0.033 13.8 13.4 1.0 1 0 0 1 1 1 0 Cobalt transport protein Tetraspanin PF00335.20 EGG21186.1 - 1.4 8.6 22.7 2.9 7.6 21.8 1.8 1 1 0 1 1 1 0 Tetraspanin family DUF2070 PF09843.9 EGG21186.1 - 1.5 7.0 13.5 1.7 6.8 13.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SapB_2 PF03489.17 EGG21187.1 - 1.3e-05 25.1 0.6 1.3e-05 25.1 0.6 2.1 3 0 0 3 3 3 1 Saposin-like type B, region 2 SapB_1 PF05184.15 EGG21187.1 - 0.01 15.9 2.1 0.012 15.7 0.1 2.3 2 1 0 2 2 2 0 Saposin-like type B, region 1 FNIP PF05725.12 EGG21188.1 - 3.6e-07 30.2 32.1 0.0092 16.1 0.4 7.6 6 2 1 7 7 7 4 FNIP Repeat SUIM_assoc PF16619.5 EGG21188.1 - 0.026 14.6 1.9 0.057 13.5 1.9 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RCC1 PF00415.18 EGG21189.1 - 1.4e-14 54.5 6.4 0.00018 22.0 0.0 6.8 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG21189.1 - 7.8e-14 51.1 3.6 0.0045 16.7 0.0 5.6 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat LupA PF18242.1 EGG21189.1 - 0.074 12.7 0.0 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Legionella ubiquitin-specific protease A domain DUF2615 PF11027.8 EGG21189.1 - 0.087 13.0 0.9 0.23 11.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) SR-25 PF10500.9 EGG21189.1 - 0.11 12.1 10.2 0.51 9.9 3.7 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PDR_CDR PF06422.12 EGG21190.1 - 0.17 11.8 1.9 0.24 11.3 1.9 1.3 1 0 0 1 1 1 0 CDR ABC transporter DUF2631 PF10939.8 EGG21190.1 - 0.2 11.5 1.6 0.39 10.6 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) Baculo_11_kDa PF06143.11 EGG21190.1 - 0.36 10.4 4.1 8.6 6.0 1.5 2.1 2 0 0 2 2 2 0 Baculovirus 11 kDa family Dscam_C PF12355.8 EGG21191.1 - 0.00069 20.6 0.3 0.00082 20.3 0.3 1.2 1 0 0 1 1 1 1 Down syndrome cell adhesion molecule C terminal Sugar_tr PF00083.24 EGG21193.1 - 3.5e-33 115.1 29.8 3.8e-20 72.2 15.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGG21193.1 - 2.5e-18 66.2 36.9 1.7e-11 43.7 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 EGG21194.1 - 6.9e-21 75.1 0.0 2.4e-20 73.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 EGG21194.1 - 7.4e-12 44.9 0.1 2.5e-11 43.2 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EGG21194.1 - 5.6e-11 42.3 0.0 3.8e-08 33.1 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGG21194.1 - 0.0021 17.3 0.0 0.31 10.3 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EGG21194.1 - 0.0034 17.1 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EGG21194.1 - 0.0041 17.0 0.0 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF2920 PF11144.8 EGG21194.1 - 0.015 14.5 0.0 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Chlorophyllase2 PF12740.7 EGG21194.1 - 0.066 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Trm5_N PF18093.1 EGG21195.1 - 0.016 15.1 0.1 0.067 13.1 0.0 2.1 2 0 0 2 2 2 0 tRNA methyltransferase 5 N-terminal domain KIP1 PF07765.12 EGG21195.1 - 0.48 10.6 3.6 0.27 11.4 0.2 2.3 2 1 1 3 3 3 0 KIP1-like protein zf-FCS PF06467.14 EGG21196.1 - 0.015 15.3 6.5 0.025 14.5 6.5 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF3330 PF11809.8 EGG21196.1 - 0.016 15.3 0.3 0.022 14.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) SR-25 PF10500.9 EGG21196.1 - 1.4 8.5 9.9 1.6 8.3 9.9 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PLATZ PF04640.14 EGG21196.1 - 9.1 7.0 10.8 1.8 9.3 6.7 1.9 2 1 0 2 2 2 0 PLATZ transcription factor PQ-loop PF04193.14 EGG21197.1 - 6.5e-20 70.7 20.6 4.9e-12 45.4 2.4 3.4 3 1 1 4 4 4 2 PQ loop repeat Peptidase_M50B PF13398.6 EGG21197.1 - 1.1 8.9 11.5 0.32 10.6 7.9 1.9 1 1 0 1 1 1 0 Peptidase M50B-like DUF2462 PF09495.10 EGG21198.1 - 0.0014 19.3 15.3 0.0014 19.3 15.3 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) HEAT_EZ PF13513.6 EGG21199.1 - 7e-37 125.4 6.6 5.1e-13 49.2 0.0 11.4 10 2 2 12 12 12 4 HEAT-like repeat HEAT PF02985.22 EGG21199.1 - 5.5e-29 97.7 8.3 0.0018 18.4 0.0 11.9 12 0 0 12 12 11 5 HEAT repeat HEAT_2 PF13646.6 EGG21199.1 - 8.3e-20 71.0 0.0 0.005 17.2 0.0 7.4 3 3 3 7 7 7 6 HEAT repeats Cnd1 PF12717.7 EGG21199.1 - 1.4e-16 60.9 0.5 0.00012 22.2 0.0 5.0 4 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGG21199.1 - 8.9e-13 48.7 0.0 0.08 13.5 0.0 6.8 5 2 2 7 7 7 3 Vacuolar 14 Fab1-binding region Arm PF00514.23 EGG21199.1 - 2.7e-11 43.1 9.6 0.068 13.2 0.0 8.6 10 0 0 10 10 9 4 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EGG21199.1 - 5.8e-11 41.6 1.7 0.0061 15.2 0.3 3.9 3 3 1 5 5 5 3 Adaptin N terminal region IBN_N PF03810.19 EGG21199.1 - 1.5e-09 37.6 0.0 1.1e-08 34.8 0.0 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EGG21199.1 - 3.2e-07 30.4 0.5 0.014 15.4 0.1 4.4 4 2 0 5 5 5 2 Domain of unknown function (DUF3385) Xpo1 PF08389.12 EGG21199.1 - 1.9e-05 24.8 0.4 0.061 13.4 0.0 4.9 5 2 0 5 5 5 1 Exportin 1-like protein MMS19_C PF12460.8 EGG21199.1 - 4.5e-05 22.7 3.3 0.11 11.5 0.0 4.2 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal DRIM PF07539.12 EGG21199.1 - 0.013 13.9 0.3 1.5 7.0 0.1 3.7 4 1 1 5 5 5 0 Down-regulated in metastasis CLASP_N PF12348.8 EGG21199.1 - 0.021 14.4 0.3 21 4.6 0.0 4.7 5 1 0 5 5 5 0 CLASP N terminal adh_short PF00106.25 EGG21201.1 - 4.5e-19 68.7 0.0 9.6e-19 67.6 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG21201.1 - 3e-06 27.0 0.0 4.7e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG21201.1 - 0.00094 19.1 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_6 PF08030.12 EGG21201.1 - 0.035 14.2 1.3 0.052 13.7 0.4 1.8 2 1 0 2 2 2 0 Ferric reductase NAD binding domain Rotamase PF00639.21 EGG21201.1 - 0.099 13.6 1.4 7.2 7.6 0.0 2.9 2 1 0 2 2 2 0 PPIC-type PPIASE domain SNF2_N PF00176.23 EGG21202.1 - 1.6e-72 244.2 0.4 1.6e-72 244.2 0.4 3.5 4 0 0 4 4 4 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG21202.1 - 7.6e-20 71.3 0.0 5.4e-19 68.6 0.0 2.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EGG21202.1 - 1e-17 64.0 0.7 6.4e-17 61.4 0.2 2.7 2 0 0 2 2 2 1 Bromodomain HSA PF07529.13 EGG21202.1 - 3.1e-14 53.0 8.4 3.1e-14 53.0 8.4 5.1 4 1 0 4 4 4 1 HSA RPN5_C PF18098.1 EGG21202.1 - 0.079 13.1 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain RCC1 PF00415.18 EGG21203.1 - 3.5e-52 174.8 21.6 5.2e-13 49.4 0.7 7.2 6 2 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG21203.1 - 1.9e-28 97.6 29.8 1.7e-09 37.2 2.6 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat PRC PF05239.16 EGG21203.1 - 0.09 12.9 0.0 21 5.3 0.0 2.5 2 0 0 2 2 2 0 PRC-barrel domain LapA_dom PF06305.11 EGG21204.1 - 0.0074 16.1 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain AWPM-19 PF05512.11 EGG21204.1 - 0.015 15.5 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 AWPM-19-like family C12orf66_like PF09404.10 EGG21205.1 - 1.1e-41 143.1 8.0 3e-34 118.6 2.1 2.9 2 1 0 2 2 2 2 KICSTOR complex C12orf66 like zf-CCCH PF00642.24 EGG21206.1 - 2.3e-08 33.7 5.2 3.8e-08 33.0 5.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EGG21206.1 - 1.9e-07 30.8 1.0 5.3e-06 26.2 0.1 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EGG21206.1 - 7.4e-06 25.9 0.7 0.0001 22.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) PWI PF01480.17 EGG21206.1 - 0.00017 21.8 0.2 0.00049 20.4 0.2 1.8 1 0 0 1 1 1 1 PWI domain zf_CCCH_4 PF18345.1 EGG21206.1 - 0.0052 16.8 4.8 0.0091 16.0 4.8 1.4 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 EGG21206.1 - 0.0099 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF5320 PF17253.2 EGG21206.1 - 0.37 11.9 2.4 2 9.6 2.4 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF4845 PF16137.5 EGG21206.1 - 0.73 10.7 6.2 0.42 11.5 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4845) PHM7_cyt PF14703.6 EGG21206.1 - 2.9 8.1 22.3 79 3.4 0.1 3.5 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter zf-CCCH_2 PF14608.6 EGG21206.1 - 4.8 7.8 5.4 9.8 6.8 5.4 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF747 PF05346.11 EGG21208.1 - 6.1e-72 242.8 9.4 1.1e-71 241.9 9.4 1.4 1 0 0 1 1 1 1 Eukaryotic membrane protein family Cyclin PF08613.11 EGG21209.1 - 2.5e-26 93.0 18.4 2.5e-26 93.0 18.4 4.4 3 1 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 EGG21209.1 - 1.1e-06 28.4 0.1 1.1e-06 28.4 0.1 2.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain SUIM_assoc PF16619.5 EGG21209.1 - 0.12 12.5 0.0 0.12 12.5 0.0 7.3 5 2 1 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 Hydrolase_4 PF12146.8 EGG21210.1 - 6e-18 65.0 0.0 1.1e-13 51.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG21210.1 - 5.9e-12 45.8 0.0 7.5e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGG21210.1 - 3.2e-08 33.5 0.0 5.8e-06 26.1 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 EGG21210.1 - 2.8e-05 23.9 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.12 EGG21210.1 - 0.00033 19.4 0.0 0.0014 17.3 0.0 1.8 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Mucin PF01456.17 EGG21210.1 - 0.00054 20.0 13.1 0.00075 19.5 13.1 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Abhydrolase_6 PF12697.7 EGG21210.1 - 0.0017 19.0 0.0 0.0026 18.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Aldo_ket_red PF00248.21 EGG21210.1 - 0.0035 16.6 0.0 0.14 11.3 0.0 2.1 1 1 1 2 2 2 1 Aldo/keto reductase family BAAT_C PF08840.11 EGG21210.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EGG21210.1 - 0.058 12.9 0.0 0.23 10.9 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family MAP65_ASE1 PF03999.12 EGG21210.1 - 0.48 9.0 3.8 0.76 8.4 3.8 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) LAT PF15234.6 EGG21210.1 - 0.95 9.2 8.1 1.4 8.6 8.1 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells Dicty_REP PF05086.12 EGG21210.1 - 1 7.2 10.7 1.3 6.9 10.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MGC-24 PF05283.11 EGG21210.1 - 4.9 7.6 8.7 9.2 6.7 8.7 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SSP160 PF06933.11 EGG21210.1 - 9.5 4.3 16.2 14 3.8 16.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DNA_ligase_A_M PF01068.21 EGG21211.1 - 1.7e-55 187.8 1.4 2.1e-55 187.5 0.1 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGG21211.1 - 2.4e-26 93.1 1.1 6.5e-26 91.7 1.1 1.7 1 0 0 1 1 1 1 DNA ligase N terminus BRCT PF00533.26 EGG21211.1 - 1.1e-16 61.0 4.1 7.5e-09 35.9 0.1 3.6 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.15 EGG21211.1 - 3.5e-16 59.6 0.0 2.3e-14 53.8 0.0 2.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 EGG21211.1 - 4.2e-15 55.9 0.1 1.9e-07 31.4 0.0 3.2 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EGG21211.1 - 2.1e-12 47.2 0.1 2e-10 40.8 0.0 3.0 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 EGG21211.1 - 4e-08 33.1 0.1 1.7e-05 24.7 0.1 2.8 2 0 0 2 2 2 1 twin BRCT domain RNA_ligase PF09414.10 EGG21211.1 - 7e-08 32.9 0.1 2.1e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 RNA ligase RTT107_BRCT_5 PF16770.5 EGG21211.1 - 0.0024 17.7 0.3 0.27 11.2 0.0 3.6 3 1 0 3 3 2 1 Regulator of Ty1 transposition protein 107 BRCT domain FAM176 PF14851.6 EGG21211.1 - 0.028 14.1 9.0 1.8 8.2 9.0 2.9 3 1 0 3 3 3 0 FAM176 family Myb_DNA-binding PF00249.31 EGG21211.1 - 0.12 12.6 0.1 0.59 10.4 0.1 2.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain NST1 PF13945.6 EGG21211.1 - 0.27 11.3 14.6 0.22 11.6 8.4 2.5 2 0 0 2 2 2 0 Salt tolerance down-regulator Nop25 PF09805.9 EGG21211.1 - 0.55 10.7 12.2 2.1 8.8 12.2 2.0 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF913 PF06025.12 EGG21211.1 - 0.61 9.0 8.4 0.4 9.6 6.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Tub_N PF16322.5 EGG21211.1 - 1 9.8 10.8 0.53 10.7 7.4 2.1 2 0 0 2 2 2 0 Tubby N-terminal RP-C_C PF11800.8 EGG21211.1 - 1.8 8.6 3.2 3.6 7.6 3.2 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region RXT2_N PF08595.11 EGG21211.1 - 2 8.4 11.8 2.9 7.9 7.8 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal Striatin PF08232.12 EGG21211.1 - 2.6 8.6 8.7 0.63 10.6 4.6 2.0 2 0 0 2 2 2 0 Striatin family SAP30_Sin3_bdg PF13867.6 EGG21212.1 - 3.7e-18 65.6 0.2 3.7e-18 65.6 0.2 3.3 2 1 1 3 3 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 TFIIA PF03153.13 EGG21212.1 - 0.00014 22.0 31.4 0.00016 21.8 31.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EGG21212.1 - 0.16 10.2 26.3 0.17 10.1 26.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.9 EGG21212.1 - 0.18 10.4 17.7 0.23 10.0 17.7 1.1 1 0 0 1 1 1 0 Macoilin family IL1_propep PF02394.16 EGG21212.1 - 0.24 12.3 0.2 0.24 12.3 0.2 2.6 2 1 0 2 2 1 0 Interleukin-1 propeptide DUF4407 PF14362.6 EGG21212.1 - 0.36 10.1 11.0 0.53 9.6 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lin-8 PF03353.15 EGG21212.1 - 0.6 9.6 19.4 1 8.9 19.4 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CSRNP_N PF16019.5 EGG21212.1 - 0.75 9.7 17.5 0.24 11.3 14.3 1.7 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Presenilin PF01080.17 EGG21212.1 - 2.3 6.9 15.3 2.6 6.7 15.3 1.2 1 0 0 1 1 1 0 Presenilin PepSY_TM PF03929.16 EGG21212.1 - 2.4 7.8 4.9 3 7.4 4.9 1.2 1 0 0 1 1 1 0 PepSY-associated TM region DUF2072 PF09845.9 EGG21212.1 - 2.5 8.3 10.8 12 6.2 6.4 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein ALMT PF11744.8 EGG21212.1 - 2.9 6.6 10.3 3.8 6.2 10.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM70 PF14967.6 EGG21212.1 - 6.3 6.2 14.2 10 5.4 14.2 1.3 1 0 0 1 1 1 0 FAM70 protein Tim54 PF11711.8 EGG21212.1 - 8.2 5.1 14.9 12 4.6 14.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4638 PF15472.6 EGG21212.1 - 8.9 6.0 13.7 12 5.5 13.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Cyclin PF08613.11 EGG21213.1 - 1.2e-12 48.5 0.2 2.6e-10 40.9 0.1 5.5 2 2 1 3 3 3 2 Cyclin Cyclin_N PF00134.23 EGG21213.1 - 0.014 15.2 0.0 0.042 13.6 0.0 1.8 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ribosomal_60s PF00428.19 EGG21213.1 - 2.9 8.5 7.0 0.31 11.6 0.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein MPP6 PF10175.9 EGG21214.1 - 9.5e-20 71.4 2.2 9.5e-20 71.4 2.2 3.1 2 1 1 3 3 3 1 M-phase phosphoprotein 6 Gly_kinase PF02595.15 EGG21215.1 - 8.3e-93 311.3 0.4 1e-92 311.0 0.4 1.0 1 0 0 1 1 1 1 Glycerate kinase family DUF3546 PF12066.8 EGG21216.1 - 4.4e-25 88.0 8.2 4.4e-25 88.0 8.2 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 EGG21216.1 - 1.6e-16 61.3 0.2 1.6e-16 61.3 0.2 3.3 3 0 0 3 3 3 2 Arsenite-resistance protein 2 DUF4187 PF13821.6 EGG21216.1 - 3.2e-10 39.6 0.7 9.8e-10 38.1 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RRM_1 PF00076.22 EGG21216.1 - 2.9e-06 27.0 0.0 7e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.7 EGG21216.1 - 0.00026 21.3 1.5 0.031 14.6 0.3 2.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EGG21216.1 - 3.6 8.7 5.1 13 6.9 2.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Proteasom_Rpn13 PF04683.13 EGG21217.1 - 4e-19 68.9 0.2 7.7e-19 68.0 0.2 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EGG21217.1 - 2e-17 63.4 0.2 3.7e-17 62.5 0.2 1.4 1 0 0 1 1 1 1 UCH-binding domain DUF3699 PF12480.8 EGG21217.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) Dicty_REP PF05086.12 EGG21217.1 - 3.6 5.4 5.5 4.6 5.1 5.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MAP65_ASE1 PF03999.12 EGG21217.1 - 3.9 6.1 9.2 5 5.7 9.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MSP1_C PF07462.11 EGG21217.1 - 5.8 5.5 7.2 8.1 5.0 7.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Peptidase_S8 PF00082.22 EGG21218.1 - 5.2e-42 144.1 1.2 9.2e-42 143.3 1.2 1.3 1 0 0 1 1 1 1 Subtilase family CemA PF03040.14 EGG21218.1 - 0.0071 16.3 1.7 0.011 15.6 1.7 1.3 1 0 0 1 1 1 1 CemA family MCR PF18509.1 EGG21219.1 - 0.13 11.8 3.8 3.5 7.3 0.5 2.8 3 0 0 3 3 3 0 Magnetochrome domain RhoGAP PF00620.27 EGG21220.1 - 1.4e-22 80.2 0.0 4.8e-22 78.4 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EGG21220.1 - 2.2e-12 47.1 0.1 2.2e-12 47.1 0.1 2.7 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Myosin_tail_1 PF01576.19 EGG21220.1 - 0.0065 14.4 11.1 0.0092 13.8 11.1 1.2 1 0 0 1 1 1 1 Myosin tail Fez1 PF06818.15 EGG21220.1 - 0.015 15.8 8.3 0.034 14.6 8.3 1.6 1 0 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.12 EGG21220.1 - 0.032 14.3 7.8 0.076 13.1 7.8 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 EGG21220.1 - 0.34 10.4 13.2 0.14 11.7 10.7 1.6 2 0 0 2 2 2 0 Intermediate filament protein DUF4407 PF14362.6 EGG21220.1 - 1 8.6 3.8 1.8 7.8 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Osmo_CC PF08946.10 EGG21220.1 - 2.7 8.3 10.3 1.1 9.6 0.1 4.2 5 0 0 5 5 5 0 Osmosensory transporter coiled coil EB PF01683.18 EGG21221.1 - 0.014 15.7 7.5 0.014 15.7 7.5 8.3 2 2 6 8 8 8 0 EB module Dickkopf_N PF04706.12 EGG21221.1 - 0.014 15.9 14.2 0.014 15.9 14.2 7.1 4 3 2 7 7 7 0 Dickkopf N-terminal cysteine-rich region Phospholip_B PF04916.13 EGG21222.1 - 4.2e-167 556.9 12.5 5e-167 556.7 12.5 1.0 1 0 0 1 1 1 1 Phospholipase B fn3 PF00041.21 EGG21223.1 - 4.3e-15 55.8 55.2 0.00088 19.6 0.2 11.2 12 1 0 12 12 12 5 Fibronectin type III domain SusE PF14292.6 EGG21223.1 - 0.00096 19.4 1.7 0.00096 19.4 1.7 7.5 7 1 0 7 7 7 1 SusE outer membrane protein EGF_2 PF07974.13 EGG21223.1 - 0.0011 19.3 12.2 0.0041 17.5 12.2 2.1 1 0 0 1 1 1 1 EGF-like domain DUF4352 PF11611.8 EGG21223.1 - 0.014 15.7 17.5 18 5.6 0.1 7.6 7 1 0 8 8 8 0 Domain of unknown function (DUF4352) SKG6 PF08693.10 EGG21223.1 - 0.086 12.3 1.7 0.22 11.0 1.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MNHE PF01899.16 EGG21223.1 - 0.15 11.8 7.9 4.2 7.1 0.6 3.1 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit EGF PF00008.27 EGG21223.1 - 0.33 11.3 7.3 2 8.8 7.3 2.6 1 0 0 1 1 1 0 EGF-like domain DUF2369 PF10179.9 EGG21223.1 - 0.97 9.9 20.1 10 6.6 1.7 5.9 6 1 1 7 7 7 0 Uncharacterised conserved protein (DUF2369) CARDB PF07705.11 EGG21223.1 - 3.5 7.9 65.4 3 8.2 1.8 11.0 5 3 4 9 9 9 0 CARDB adh_short PF00106.25 EGG21224.1 - 3.7e-45 153.8 0.0 7.4e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG21224.1 - 1.6e-25 90.1 0.0 2.8e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG21224.1 - 4.1e-09 36.6 0.0 9.6e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 KR domain fn3 PF00041.21 EGG21224.1 - 6.6e-05 23.2 30.3 0.0074 16.6 1.8 7.0 7 2 0 7 7 7 2 Fibronectin type III domain EGF_2 PF07974.13 EGG21224.1 - 0.00084 19.6 12.6 0.0034 17.7 12.6 2.2 1 0 0 1 1 1 1 EGF-like domain DUF4352 PF11611.8 EGG21224.1 - 0.024 14.9 9.3 38 4.6 0.0 5.6 5 1 1 6 6 6 0 Domain of unknown function (DUF4352) SusE PF14292.6 EGG21224.1 - 0.025 14.8 0.5 0.025 14.8 0.5 4.7 3 1 1 4 4 4 0 SusE outer membrane protein THF_DHG_CYH_C PF02882.19 EGG21224.1 - 0.026 13.9 0.5 0.25 10.6 0.0 2.7 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 EGG21224.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 EGG21224.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EGF PF00008.27 EGG21224.1 - 0.58 10.5 8.0 2.8 8.3 8.0 2.3 1 0 0 1 1 1 0 EGF-like domain CARDB PF07705.11 EGG21224.1 - 3.9 7.8 37.3 2.7 8.3 2.1 6.8 3 2 1 5 5 5 0 CARDB Cupin_8 PF13621.6 EGG21225.1 - 9.7e-55 186.0 2.1 4.1e-54 184.0 2.1 1.8 1 1 0 1 1 1 1 Cupin-like domain DUF2040 PF09745.9 EGG21226.1 - 2.7e-31 108.1 20.5 2.7e-31 108.1 20.5 3.6 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF5102 PF17104.5 EGG21227.1 - 0.0011 19.1 1.1 0.0011 19.1 1.1 7.6 4 2 2 6 6 6 3 Domain of unknown function (DUF5102) zf-DBF PF07535.12 EGG21227.1 - 0.042 13.9 3.7 0.11 12.6 3.7 1.7 1 0 0 1 1 1 0 DBF zinc finger DYW_deaminase PF14432.6 EGG21227.1 - 0.26 11.1 0.0 0.26 11.1 0.0 2.8 3 0 0 3 3 3 0 DYW family of nucleic acid deaminases DUF3614 PF12267.8 EGG21227.1 - 4.5 7.7 12.9 4.5 7.7 4.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) P21-Arc PF04062.14 EGG21228.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 ARP2/3 complex ARPC3 (21 kDa) subunit SLC12 PF03522.15 EGG21228.1 - 0.074 12.1 1.6 0.12 11.4 1.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF5432 PF17497.2 EGG21229.1 - 0.12 12.5 1.1 0.45 10.7 1.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5432) DHR-2 PF06920.13 EGG21230.1 - 8.2e-85 285.4 28.4 6.7e-44 150.4 13.4 3.5 3 1 0 3 3 3 2 Dock homology region 2 DOCK_N PF16172.5 EGG21230.1 - 2.4e-62 211.0 0.0 9e-62 209.1 0.0 2.0 1 1 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 EGG21230.1 - 5.5e-44 150.3 1.2 7.5e-43 146.6 1.2 2.7 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 EGG21230.1 - 2.9e-06 26.8 0.0 7.1e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG21230.1 - 0.00036 20.2 0.0 0.00082 19.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGG21230.1 - 0.0038 17.0 0.1 0.042 13.7 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain Guanylate_kin PF00625.21 EGG21231.1 - 1.8e-60 203.8 0.0 2e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 EGG21231.1 - 9.6e-07 29.4 0.0 1.6e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGG21231.1 - 1.6e-05 24.9 0.0 7.1e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EGG21231.1 - 0.00087 19.5 0.0 0.013 15.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG21231.1 - 0.0013 19.2 0.0 0.0016 18.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGG21231.1 - 0.002 17.8 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EGG21231.1 - 0.0046 17.5 0.0 0.0064 17.0 0.0 1.6 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGG21231.1 - 0.007 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_17 PF13207.6 EGG21231.1 - 0.0091 16.4 0.3 0.11 13.0 0.3 2.3 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EGG21231.1 - 0.012 15.4 0.2 1.1 9.1 0.1 2.3 2 1 0 2 2 2 0 Deoxynucleoside kinase NTPase_1 PF03266.15 EGG21231.1 - 0.016 15.1 0.2 0.032 14.2 0.2 1.6 1 1 1 2 2 2 0 NTPase AAA_22 PF13401.6 EGG21231.1 - 0.024 14.9 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EGG21231.1 - 0.024 14.3 0.3 2 8.0 0.3 2.3 1 1 0 1 1 1 0 Thymidylate kinase AAA_28 PF13521.6 EGG21231.1 - 0.039 14.2 0.0 0.089 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGG21231.1 - 0.046 13.6 0.1 0.098 12.6 0.0 1.7 2 1 0 2 2 2 0 Rad17 P-loop domain ADK PF00406.22 EGG21231.1 - 0.056 13.5 0.4 2.5 8.2 0.1 2.5 2 1 1 3 3 3 0 Adenylate kinase MeaB PF03308.16 EGG21231.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 EGG21231.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.10 EGG21231.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 cobW PF02492.19 EGG21231.1 - 0.14 11.8 0.1 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EGG21231.1 - 0.23 11.1 0.1 0.35 10.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGG21231.1 - 0.34 11.4 3.1 0.54 10.7 3.1 1.6 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 EGG21232.1 - 5.3e-44 149.7 1.0 6.3e-44 149.4 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG21232.1 - 1.2e-27 96.5 0.0 2.5e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG21232.1 - 2.6e-15 56.3 0.5 3.1e-15 56.1 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG21232.1 - 1.1e-10 41.2 0.1 1.7e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGG21232.1 - 5.8e-05 23.1 1.1 0.0057 16.6 0.2 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGG21232.1 - 0.00016 21.7 0.0 0.00031 20.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGG21232.1 - 0.0061 16.0 0.0 0.012 15.0 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EGG21232.1 - 0.035 14.1 0.1 0.27 11.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain MMR_HSR1_Xtn PF16897.5 EGG21232.1 - 0.052 13.6 0.2 0.091 12.8 0.2 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Saccharop_dh_N PF04455.12 EGG21232.1 - 0.081 13.3 0.1 16 6.0 0.0 2.2 2 0 0 2 2 2 0 LOR/SDH bifunctional enzyme conserved region ICL PF00463.21 EGG21233.1 - 1.7e-102 343.6 0.7 2.7e-51 174.6 0.0 2.2 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 EGG21233.1 - 6.5e-14 52.0 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF3430 PF11912.8 EGG21235.1 - 5.4e-07 29.9 20.4 5.4e-07 29.9 20.4 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3430) DUF3430 PF11912.8 EGG21236.1 - 1.7e-09 38.0 25.5 1.7e-09 38.0 25.5 2.5 2 2 0 2 2 2 1 Protein of unknown function (DUF3430) Cys_knot PF00007.22 EGG21236.1 - 0.25 11.7 9.8 0.34 11.2 8.3 2.0 1 1 1 2 2 2 0 Cystine-knot domain DUF4719 PF15843.5 EGG21236.1 - 4.6 7.3 8.5 18 5.4 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) DUF3430 PF11912.8 EGG21237.1 - 4.4e-14 53.0 11.6 4.4e-14 53.0 11.6 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF3430) FoP_duplication PF13865.6 EGG21237.1 - 0.027 15.0 0.2 0.027 15.0 0.2 2.4 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 Not3 PF04065.15 EGG21238.1 - 9e-78 260.9 18.4 9e-78 260.9 18.4 3.6 3 1 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EGG21238.1 - 9.5e-40 135.7 14.7 9.5e-40 135.7 14.7 4.6 3 1 0 3 3 3 1 NOT2 / NOT3 / NOT5 family DUF4407 PF14362.6 EGG21238.1 - 2.8 7.2 49.1 0.45 9.8 17.5 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4407) Cofilin_ADF PF00241.20 EGG21240.1 - 1.7e-15 56.8 0.0 2.1e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-RVT PF13966.6 EGG21242.1 - 0.00026 21.6 0.4 0.001 19.7 0.5 1.9 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RCC1 PF00415.18 EGG21244.1 - 2.7e-44 149.6 2.6 2e-12 47.5 0.0 7.9 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG21244.1 - 2e-25 88.0 28.4 3.6e-05 23.4 0.9 7.9 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Profilin PF00235.19 EGG21244.1 - 0.014 15.7 0.5 0.031 14.5 0.5 1.6 1 0 0 1 1 1 0 Profilin Reg_prop PF07494.11 EGG21244.1 - 0.039 14.2 1.0 86 3.9 0.0 4.5 5 0 0 5 5 5 0 Two component regulator propeller Kelch_2 PF07646.15 EGG21244.1 - 0.15 12.1 6.0 4.6 7.4 0.0 4.4 4 0 0 4 4 4 0 Kelch motif SBBP PF06739.11 EGG21244.1 - 0.16 12.0 5.1 0.63 10.1 0.5 2.7 2 0 0 2 2 2 0 Beta-propeller repeat RsfS PF02410.15 EGG21244.1 - 0.49 10.8 1.9 5 7.6 0.2 2.4 1 1 1 2 2 2 0 Ribosomal silencing factor during starvation HATPase_c PF02518.26 EGG21245.1 - 7.1e-29 100.6 0.3 1.8e-28 99.2 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGG21245.1 - 1.6e-20 73.3 0.1 2.1e-19 69.7 0.1 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EGG21245.1 - 7.4e-17 61.1 0.1 2.3e-16 59.6 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF5428 PF17493.2 EGG21245.1 - 0.14 12.6 0.4 0.78 10.2 0.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5428) DUF2052 PF09747.9 EGG21245.1 - 1.4 9.0 7.9 0.63 10.1 0.3 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) AMP-binding PF00501.28 EGG21246.1 - 3.3e-77 259.9 0.0 4e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG21246.1 - 1.8e-20 73.6 0.1 7.9e-20 71.6 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SR-25 PF10500.9 EGG21246.1 - 5.7 6.5 6.9 9.3 5.8 6.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Memo PF01875.17 EGG21247.1 - 1.9e-73 246.9 0.0 2.2e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Arm-DNA-bind_5 PF17293.2 EGG21248.1 - 0.04 14.4 4.3 0.045 14.2 1.1 2.5 2 0 0 2 2 2 0 Arm DNA-binding domain CAP PF00188.26 EGG21249.1 - 1.8e-23 83.7 6.7 2.2e-15 57.6 0.3 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family DUF1364 PF07102.12 EGG21249.1 - 0.017 14.9 4.8 0.37 10.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1364) TFIIA PF03153.13 EGG21249.1 - 0.31 11.0 9.7 0.48 10.4 9.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TIG PF01833.24 EGG21250.1 - 5.2e-21 74.5 36.4 5e-10 39.3 6.1 5.7 5 1 1 6 6 6 4 IPT/TIG domain EGF_Tenascin PF18720.1 EGG21250.1 - 3.3e-05 23.8 11.5 8.7e-05 22.5 11.5 1.8 1 0 0 1 1 1 1 Tenascin EGF domain Lectin_C PF00059.21 EGG21250.1 - 0.00062 20.5 6.7 0.00073 20.2 0.1 3.5 3 1 1 4 4 4 1 Lectin C-type domain EGF_2 PF07974.13 EGG21250.1 - 0.34 11.3 8.9 0.73 10.3 8.9 1.6 1 0 0 1 1 1 0 EGF-like domain Transketolase_N PF00456.21 EGG21251.1 - 2.9e-108 361.8 0.0 4.8e-108 361.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EGG21251.1 - 6.2e-44 149.8 0.0 2e-43 148.1 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGG21251.1 - 3.2e-14 52.9 0.0 1.5e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EGG21251.1 - 3e-08 33.2 0.1 6.9e-07 28.7 0.1 2.4 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EGG21251.1 - 1.6e-05 24.7 0.3 0.00042 20.1 0.3 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EGG21251.1 - 0.015 14.3 0.1 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Ras PF00071.22 EGG21252.1 - 1.3e-54 184.2 0.0 1.6e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG21252.1 - 1.7e-16 60.5 0.0 2.9e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG21252.1 - 1.4e-06 27.9 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGG21252.1 - 0.00015 21.7 0.0 0.39 10.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGG21252.1 - 0.0041 16.7 0.0 0.027 14.0 0.0 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGG21252.1 - 0.043 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4150 PF13665.6 EGG21252.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) DUF3783 PF12646.7 EGG21252.1 - 0.16 12.0 0.0 0.41 10.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) Adaptin_N PF01602.20 EGG21253.1 - 4.5e-134 447.9 22.2 5.6e-134 447.6 22.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGG21253.1 - 6.9e-27 94.5 11.6 9.8e-21 74.5 1.6 3.9 3 1 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 AP3B1_C PF14796.6 EGG21253.1 - 6.1e-14 52.5 0.1 2.1e-13 50.8 0.1 1.9 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_2 PF13646.6 EGG21253.1 - 2.4e-11 43.9 0.6 1.5e-05 25.3 0.3 4.1 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.22 EGG21253.1 - 1.6e-06 27.9 9.9 0.029 14.6 0.0 7.4 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 EGG21253.1 - 1.8e-06 28.3 0.1 0.16 12.5 0.0 4.6 3 1 0 3 3 3 2 HEAT-like repeat CDC27 PF09507.10 EGG21253.1 - 0.00082 18.9 20.4 0.00082 18.9 20.4 1.9 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 Cohesin_HEAT PF12765.7 EGG21253.1 - 0.025 14.9 7.0 0.63 10.4 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Mpp10 PF04006.12 EGG21253.1 - 2.3 6.6 33.9 0.0054 15.2 23.3 1.8 2 0 0 2 2 2 0 Mpp10 protein Pkinase PF00069.25 EGG21254.1 - 3.1e-62 210.3 4.2 3.6e-62 210.1 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain RNA_pol_Rbc25 PF08292.12 EGG21254.1 - 5.5e-32 110.7 0.1 5.5e-32 110.7 0.1 5.1 5 1 0 5 5 5 1 RNA polymerase III subunit Rpc25 Pkinase_Tyr PF07714.17 EGG21254.1 - 1.3e-23 83.6 0.8 4.3e-23 81.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase SHS2_Rpb7-N PF03876.17 EGG21254.1 - 1e-09 38.6 0.0 2.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 SUIM_assoc PF16619.5 EGG21254.1 - 0.057 13.5 0.0 0.057 13.5 0.0 9.2 6 5 1 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 S1 PF00575.23 EGG21254.1 - 0.44 10.9 0.0 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 S1 RNA binding domain ETRAMP PF09716.10 EGG21254.1 - 0.69 10.0 2.9 20 5.4 0.0 3.2 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) BUD22 PF09073.10 EGG21255.1 - 0.07 12.5 32.8 0.1 11.9 32.8 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EGG21255.1 - 0.43 8.7 29.0 0.59 8.3 29.0 1.1 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 EGG21255.1 - 0.5 10.0 23.8 0.81 9.3 23.8 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Presenilin PF01080.17 EGG21255.1 - 6.2 5.5 18.3 12 4.6 18.3 1.4 1 0 0 1 1 1 0 Presenilin Cwf_Cwc_15 PF04889.12 EGG21255.1 - 9.4 5.9 43.3 18 5.0 43.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Lipase_GDSL_2 PF13472.6 EGG21257.1 - 6.2e-16 59.3 2.5 1.7e-15 57.8 2.5 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CE2_N PF17996.1 EGG21257.1 - 2.9e-15 56.2 0.0 1.3e-14 54.1 0.0 2.1 3 0 0 3 3 3 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL PF00657.22 EGG21257.1 - 3.2e-08 33.8 0.0 7.6e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SoxZ PF08770.11 EGG21257.1 - 0.15 11.9 0.1 1.1 9.1 0.0 2.3 2 1 0 2 2 2 0 Sulphur oxidation protein SoxZ Sex_peptide PF08138.11 EGG21257.1 - 0.15 12.2 0.2 0.35 11.0 0.2 1.6 1 0 0 1 1 1 0 Sex peptide (SP) family Pre-PUA PF17832.1 EGG21258.1 - 1.3e-24 86.6 0.7 4.6e-24 84.9 0.7 2.0 1 0 0 1 1 1 1 Pre-PUA-like domain SUI1 PF01253.22 EGG21258.1 - 5.9e-14 52.3 2.6 5.1e-13 49.3 0.3 2.7 2 0 0 2 2 2 1 Translation initiation factor SUI1 SWIB PF02201.18 EGG21258.1 - 0.0009 19.1 0.0 0.003 17.4 0.0 1.9 1 0 0 1 1 1 1 SWIB/MDM2 domain PI3K_1B_p101 PF10486.9 EGG21258.1 - 0.0028 15.5 6.2 0.0043 14.9 6.2 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RRN3 PF05327.11 EGG21258.1 - 0.0051 15.4 9.1 0.0072 14.9 9.1 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EGG21258.1 - 0.0073 14.7 8.1 0.0097 14.3 8.1 1.1 1 0 0 1 1 1 1 CDC45-like protein RNA_pol_Rpc4 PF05132.14 EGG21258.1 - 0.0089 16.5 0.3 0.015 15.7 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase III RPC4 PUA PF01472.20 EGG21258.1 - 0.021 14.7 0.0 0.06 13.3 0.0 1.9 1 0 0 1 1 1 0 PUA domain GNAT_acetyltr_2 PF13718.6 EGG21258.1 - 0.027 13.9 2.7 0.045 13.2 2.7 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Nexin_C PF08628.12 EGG21258.1 - 0.03 14.9 1.4 0.095 13.3 1.4 1.8 1 0 0 1 1 1 0 Sorting nexin C terminal TrmB PF01978.19 EGG21258.1 - 0.08 12.8 0.0 0.35 10.8 0.1 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB VIT1 PF01988.19 EGG21258.1 - 0.11 12.4 3.6 0.17 11.7 3.6 1.2 1 0 0 1 1 1 0 VIT family HARE-HTH PF05066.13 EGG21258.1 - 0.12 12.8 0.1 0.91 10.0 0.0 2.5 3 0 0 3 3 2 0 HB1, ASXL, restriction endonuclease HTH domain DDHD PF02862.17 EGG21258.1 - 0.13 12.4 0.9 0.24 11.6 0.9 1.4 1 0 0 1 1 1 0 DDHD domain CPSF100_C PF13299.6 EGG21258.1 - 0.13 12.4 6.8 0.25 11.5 6.8 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Sigma70_ner PF04546.13 EGG21258.1 - 0.15 12.0 14.9 0.44 10.4 14.9 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 EGG21258.1 - 0.18 11.5 17.7 0.38 10.4 17.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 EGG21258.1 - 0.2 9.7 12.6 0.3 9.1 12.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF5523 PF17661.1 EGG21258.1 - 0.21 11.2 16.8 0.38 10.4 16.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Merozoite_SPAM PF07133.11 EGG21258.1 - 0.27 11.2 31.2 0.45 10.5 31.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2052 PF09747.9 EGG21258.1 - 0.29 11.2 18.6 0.18 11.9 16.1 1.9 3 0 0 3 3 1 0 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 EGG21258.1 - 0.36 9.0 20.7 0.45 8.7 18.6 1.8 2 0 0 2 2 2 0 Nop14-like family RNase_H2_suC PF08615.11 EGG21258.1 - 0.41 10.8 2.9 0.89 9.7 2.9 1.6 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) TFIIF_alpha PF05793.12 EGG21258.1 - 0.67 8.5 20.7 1.2 7.6 20.7 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pes-10 PF07149.11 EGG21258.1 - 1.1 8.3 16.9 2.6 7.0 15.9 2.0 2 0 0 2 2 2 0 Pes-10 CobT PF06213.12 EGG21258.1 - 1.3 8.3 17.2 2.1 7.7 17.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 EGG21258.1 - 1.5 8.2 23.9 2.4 7.5 23.9 1.3 1 0 0 1 1 1 0 SDA1 HSP90 PF00183.18 EGG21258.1 - 1.5 7.6 20.2 0.075 11.9 14.7 1.6 2 0 0 2 2 2 0 Hsp90 protein DUF2457 PF10446.9 EGG21258.1 - 2.2 7.3 23.2 4 6.5 23.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) EIIBC-GUT_N PF03612.14 EGG21258.1 - 2.4 7.8 5.5 5.5 6.7 5.5 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4820 PF16091.5 EGG21258.1 - 3.3 7.0 10.7 6.8 6.0 10.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TRAP_alpha PF03896.16 EGG21258.1 - 5 6.2 11.2 8 5.6 11.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PDDEXK_6 PF04720.12 EGG21258.1 - 5.6 6.9 12.6 11 5.9 12.6 1.4 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Presenilin PF01080.17 EGG21258.1 - 6.1 5.5 9.0 9.4 4.9 9.0 1.2 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 EGG21258.1 - 6.3 6.5 14.5 13 5.5 14.5 1.4 1 0 0 1 1 1 0 FAM176 family PTPRCAP PF15713.5 EGG21258.1 - 6.3 7.1 16.9 12 6.1 16.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Vfa1 PF08432.10 EGG21258.1 - 9.7 6.5 16.1 25 5.1 16.1 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 WD40 PF00400.32 EGG21259.1 - 1.5e-32 111.1 25.2 5.4e-08 33.4 0.5 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG21259.1 - 2.7e-17 62.8 0.2 0.00014 22.1 0.4 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 EGG21259.1 - 6.7e-12 44.7 0.9 1.5e-11 43.6 0.9 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like SprA-related PF12118.8 EGG21259.1 - 0.34 10.0 8.9 0.87 8.7 8.9 1.6 1 0 0 1 1 1 0 SprA-related family FemAB PF02388.16 EGG21259.1 - 7.7 5.3 9.4 0.062 12.2 0.2 1.8 2 0 0 2 2 2 0 FemAB family DSS1_SEM1 PF05160.13 EGG21260.1 - 2e-13 50.2 16.5 3.5e-13 49.4 16.5 1.4 1 0 0 1 1 1 1 DSS1/SEM1 family PEMT PF04191.13 EGG21261.1 - 3.2e-29 101.4 0.7 4.4e-29 101.0 0.7 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.16 EGG21261.1 - 2.4e-05 24.3 1.9 3.3e-05 23.9 1.9 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase His_Phos_1 PF00300.22 EGG21262.1 - 1.3e-15 57.6 0.2 7e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SRR1 PF07985.12 EGG21265.1 - 2.8e-14 52.9 0.0 5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 SRR1 Secretin_N_2 PF07655.13 EGG21265.1 - 0.093 13.3 1.1 0.17 12.4 1.1 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain SpoIIIAH PF12685.7 EGG21265.1 - 0.68 9.7 10.4 1 9.1 10.4 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein APG6_N PF17675.1 EGG21268.1 - 0.015 15.8 19.5 0.015 15.8 19.5 5.5 2 1 3 5 5 5 0 Apg6 coiled-coil region DUF1192 PF06698.11 EGG21268.1 - 0.099 12.7 2.8 0.13 12.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Hemerythrin PF01814.23 EGG21268.1 - 0.9 10.2 7.3 0.25 12.0 3.5 2.1 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Cyclin_N PF00134.23 EGG21269.1 - 6.5e-45 152.0 2.0 8.2e-43 145.2 0.2 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGG21269.1 - 2.6e-33 114.6 0.4 4.6e-33 113.8 0.4 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain TFIIB PF00382.19 EGG21269.1 - 0.49 10.5 2.6 0.58 10.2 0.8 2.0 2 0 0 2 2 2 0 Transcription factor TFIIB repeat PX PF00787.24 EGG21270.1 - 7.4e-15 54.9 0.5 1.4e-14 54.0 0.5 1.5 1 0 0 1 1 1 1 PX domain DUF5595 PF18077.1 EGG21270.1 - 1.6 8.9 5.5 0.38 10.9 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) T4-Gluco-transf PF09198.10 EGG21271.1 - 0.1 12.3 0.2 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase CBM49 PF09478.10 EGG21273.1 - 1e-18 67.4 0.2 1.4e-18 67.0 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF5083 PF16890.5 EGG21273.1 - 0.061 13.0 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) COesterase PF00135.28 EGG21274.1 - 2.7e-13 49.6 0.1 5.9e-13 48.5 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG21274.1 - 1.4e-10 41.4 0.1 2.1e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG21274.1 - 2.5e-06 26.9 0.1 0.00037 19.8 0.1 2.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG21274.1 - 0.00066 20.4 0.2 0.00091 19.9 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGG21274.1 - 0.001 18.6 0.0 0.081 12.4 0.0 2.7 2 1 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.20 EGG21274.1 - 0.0014 18.8 0.0 0.0022 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 EGG21274.1 - 0.044 13.6 0.0 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 EGG21274.1 - 0.083 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase PF00151.19 EGG21274.1 - 0.097 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipase NPL4 PF05021.15 EGG21275.1 - 2.9e-24 86.0 0.6 1.9e-15 57.0 0.0 3.3 1 1 1 2 2 2 2 NPL4 family JAB PF01398.21 EGG21275.1 - 9.6e-07 28.8 0.0 2.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UN_NPL4 PF11543.8 EGG21275.1 - 0.0026 18.2 0.0 0.0062 17.0 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 YukD PF08817.10 EGG21275.1 - 0.032 14.9 0.0 0.058 14.1 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD FKBP_C PF00254.28 EGG21276.1 - 3.9e-36 123.2 0.0 4.4e-36 123.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Rota_NS35 PF02509.14 EGG21276.1 - 0.17 10.9 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 TMEM51 PF15345.6 EGG21277.1 - 0.00089 19.2 22.9 0.062 13.1 2.4 2.5 2 0 0 2 2 2 2 Transmembrane protein 51 Spt20 PF12090.8 EGG21277.1 - 0.0013 18.4 23.1 0.0013 18.4 23.1 3.6 3 0 0 3 3 3 1 Spt20 family RLL PF10036.9 EGG21277.1 - 0.0056 16.6 0.7 0.0056 16.6 0.7 2.7 3 0 0 3 3 3 2 RNA transcription, translation and transport factor protein DUF2052 PF09747.9 EGG21277.1 - 3.3 7.8 22.0 21 5.2 0.3 3.6 4 0 0 4 4 4 0 Coiled-coil domain containing protein (DUF2052) EPL1 PF10513.9 EGG21277.1 - 8.8 6.7 34.3 0.17 12.3 8.5 3.7 3 1 0 3 3 3 0 Enhancer of polycomb-like Rxt3 PF08642.10 EGG21277.1 - 9.9 7.0 12.8 20 6.0 0.7 2.7 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Tim54 PF11711.8 EGG21277.1 - 9.9 4.8 20.3 10 4.8 0.9 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Ras PF00071.22 EGG21278.1 - 1.4e-34 119.0 0.2 3.2e-34 117.9 0.2 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG21278.1 - 5.3e-18 65.4 0.0 5.3e-18 65.4 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGG21278.1 - 1.4e-06 28.0 0.0 1.1e-05 25.1 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG21278.1 - 1.6e-05 24.9 0.0 6e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EGG21278.1 - 2.9e-05 23.6 0.3 0.00021 20.8 0.3 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGG21278.1 - 0.00048 20.1 0.7 0.78 9.6 0.1 3.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EGG21278.1 - 0.077 13.4 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain NADH_B2 PF14813.6 EGG21279.1 - 9.4e-05 22.1 3.8 0.00012 21.8 3.8 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 CBM_11 PF03425.13 EGG21279.1 - 0.019 14.8 0.6 0.019 14.8 0.6 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) VPS9 PF02204.18 EGG21280.1 - 6.3e-23 81.0 0.4 1.7e-22 79.6 0.4 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH PF00169.29 EGG21280.1 - 0.023 15.2 1.0 0.052 14.1 0.0 2.2 2 0 0 2 2 2 0 PH domain DUF3439 PF11921.8 EGG21280.1 - 0.28 11.2 6.5 0.68 9.9 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.25 EGG21282.1 - 6.3e-67 225.7 0.0 8.6e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21282.1 - 6.8e-47 159.9 0.3 2.3e-46 158.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 EGG21282.1 - 3.2e-16 59.4 0.1 1.2e-15 57.5 0.1 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EGG21282.1 - 3e-05 23.0 0.0 4.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGG21282.1 - 8.8e-05 21.9 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGG21282.1 - 0.024 13.6 0.2 0.088 11.7 0.2 1.7 1 1 0 1 1 1 0 Haspin like kinase domain F-box-like PF12937.7 EGG21283.1 - 0.0012 18.7 0.7 0.0023 17.8 0.7 1.5 1 0 0 1 1 1 1 F-box-like FYDLN_acid PF09538.10 EGG21283.1 - 0.22 12.2 4.3 2.2 9.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) WD40 PF00400.32 EGG21284.1 - 3.7e-11 43.4 10.1 0.072 14.0 0.4 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG21284.1 - 1.3e-08 35.1 0.1 0.24 11.7 0.0 4.7 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Mucin PF01456.17 EGG21284.1 - 0.00037 20.5 13.1 0.00064 19.7 13.1 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Frtz PF11768.8 EGG21284.1 - 0.0044 15.4 0.2 0.016 13.6 0.0 1.9 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Striatin PF08232.12 EGG21284.1 - 0.039 14.5 2.4 0.068 13.8 2.4 1.3 1 0 0 1 1 1 0 Striatin family VWA_N PF08399.11 EGG21284.1 - 0.077 13.5 2.1 0.16 12.5 2.1 1.5 1 0 0 1 1 1 0 VWA N-terminal DUF3439 PF11921.8 EGG21284.1 - 0.75 9.8 13.2 0.2 11.6 9.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Spt20 PF12090.8 EGG21284.1 - 1.3 8.6 11.9 2.3 7.8 11.9 1.3 1 0 0 1 1 1 0 Spt20 family MGC-24 PF05283.11 EGG21284.1 - 2.3 8.7 10.9 6.1 7.3 10.9 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AtuA PF07287.11 EGG21285.1 - 3.1e-110 368.2 0.0 4e-110 367.8 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Metallophos PF00149.28 EGG21286.1 - 1e-35 124.1 0.1 1.4e-35 123.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG21286.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Diphthami_syn_2 PF01902.17 EGG21287.1 - 5.2e-43 147.1 0.1 1.4e-42 145.7 0.1 1.7 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EGG21287.1 - 2.2e-26 92.3 0.0 8e-14 51.7 0.0 2.6 2 0 0 2 2 2 2 Endoribonuclease L-PSP Sulfate_transp PF00916.20 EGG21288.1 - 5.8e-103 344.6 27.4 8.6e-103 344.0 27.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGG21288.1 - 1.7e-14 53.5 0.1 3.2e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGG21288.1 - 0.0012 19.2 4.5 0.0012 19.2 4.5 3.2 3 1 1 4 4 4 1 Molybdate transporter of MFS superfamily YdjM PF04307.14 EGG21288.1 - 0.11 11.8 1.1 0.24 10.7 0.2 1.9 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Menin PF05053.13 EGG21288.1 - 2.7 6.2 6.0 3.9 5.7 6.0 1.1 1 0 0 1 1 1 0 Menin HAP2-GCS1 PF10699.9 EGG21289.1 - 2e-16 59.7 0.8 5.3e-16 58.3 0.8 1.7 1 0 0 1 1 1 1 Male gamete fusion factor DUF3139 PF11337.8 EGG21289.1 - 0.0082 16.8 5.2 0.35 11.6 0.2 3.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3139) NS3_envE PF02723.14 EGG21289.1 - 0.45 10.6 9.9 0.38 10.9 3.6 2.4 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E DUF4834 PF16118.5 EGG21289.1 - 0.5 11.3 14.1 0.72 10.8 9.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) HD PF01966.22 EGG21290.1 - 0.0059 16.8 0.0 0.0086 16.3 0.0 1.3 1 0 0 1 1 1 1 HD domain Top6b_C PF18000.1 EGG21290.1 - 0.081 13.1 0.2 0.14 12.3 0.2 1.4 1 0 0 1 1 1 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain Ras PF00071.22 EGG21291.1 - 9.8e-36 122.8 0.0 2.4e-35 121.5 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG21291.1 - 9.7e-15 54.9 0.2 1.3e-13 51.2 0.0 2.6 2 2 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGG21291.1 - 6.2e-05 22.6 0.2 0.00015 21.4 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGG21291.1 - 0.002 18.0 0.0 0.0088 16.0 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Arf PF00025.21 EGG21291.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Hep_59 PF07052.11 EGG21291.1 - 0.22 12.3 4.7 0.38 11.5 4.7 1.4 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Herpes_pp85 PF04637.12 EGG21291.1 - 0.37 9.2 8.0 0.54 8.6 8.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PAP1 PF08601.10 EGG21291.1 - 0.64 9.7 15.0 0.96 9.1 15.0 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.9 EGG21291.1 - 0.68 8.4 14.1 0.77 8.2 14.1 1.1 1 0 0 1 1 1 0 Macoilin family AP3D1 PF06375.11 EGG21291.1 - 1.8 8.8 9.6 2.6 8.2 9.6 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Miga PF10265.9 EGG21291.1 - 5.4 5.9 14.3 7.3 5.4 14.3 1.2 1 0 0 1 1 1 0 Mitoguardin Peptidase_S9 PF00326.21 EGG21293.1 - 2.7e-46 157.7 0.0 5.4e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 EGG21293.1 - 9.8e-33 113.5 6.4 9.2e-32 110.3 6.4 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Spore_GerQ PF09671.10 EGG21293.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) Palm_thioest PF02089.15 EGG21294.1 - 2e-79 266.8 0.1 2.3e-79 266.6 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EGG21294.1 - 0.00011 21.9 0.1 0.0002 21.0 0.1 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_2 PF01674.18 EGG21294.1 - 0.00034 20.2 0.0 0.0027 17.2 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 2) Ezh2_MCSS PF18600.1 EGG21294.1 - 0.034 13.8 0.1 0.063 12.9 0.1 1.5 1 0 0 1 1 1 0 MCSS domain PAC1 PF16094.5 EGG21296.1 - 5e-17 62.0 4.2 2.4e-16 59.8 4.2 1.8 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 LRR_6 PF13516.6 EGG21298.1 - 2.6e-17 61.3 23.0 0.0047 16.9 0.0 9.4 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.7 EGG21298.1 - 2.3e-07 31.0 18.2 0.013 16.0 1.0 6.7 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGG21298.1 - 3.4e-06 26.8 3.0 2.8 8.8 0.0 6.5 8 0 0 8 8 8 1 Leucine Rich Repeat Carm_PH PF17888.1 EGG21298.1 - 4.6e-06 26.9 1.2 1.2e-05 25.5 0.5 2.1 2 0 0 2 2 2 1 Carmil pleckstrin homology domain CARMIL_C PF16000.5 EGG21298.1 - 0.00027 20.7 17.0 0.00066 19.4 17.0 1.7 1 1 0 1 1 1 1 CARMIL C-terminus LRR_8 PF13855.6 EGG21298.1 - 0.0018 18.0 10.8 0.075 12.8 5.6 4.7 3 2 0 3 3 3 1 Leucine rich repeat Myosin_TH1 PF06017.13 EGG21298.1 - 0.0032 17.2 1.5 0.0074 16.0 1.5 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding PH_3 PF14593.6 EGG21298.1 - 0.0036 17.4 3.2 0.0065 16.6 1.5 2.3 2 0 0 2 2 2 1 PH domain AAA PF00004.29 EGG21299.1 - 3.8e-36 124.4 0.1 9.2e-36 123.2 0.1 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG21299.1 - 6.1e-08 32.3 0.4 1.2e-07 31.4 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 EGG21299.1 - 1.2e-06 28.4 0.0 6.6e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGG21299.1 - 1.8e-06 28.4 0.3 5.3e-05 23.7 0.3 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EGG21299.1 - 8.7e-06 25.8 0.1 3.5e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGG21299.1 - 9.5e-06 25.9 0.7 0.046 14.0 0.1 3.2 1 1 2 3 3 3 2 AAA domain AAA_18 PF13238.6 EGG21299.1 - 1.7e-05 25.4 0.1 7.6e-05 23.3 0.0 2.2 3 0 0 3 3 1 1 AAA domain AAA_33 PF13671.6 EGG21299.1 - 7.9e-05 22.8 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGG21299.1 - 0.0001 22.3 0.0 0.00043 20.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EGG21299.1 - 0.00014 22.0 0.1 0.00093 19.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EGG21299.1 - 0.00041 19.7 0.0 0.001 18.4 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 EGG21299.1 - 0.00042 20.1 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGG21299.1 - 0.0005 19.9 0.0 0.0016 18.2 0.0 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EGG21299.1 - 0.0032 17.8 0.0 0.0087 16.4 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_17 PF13207.6 EGG21299.1 - 0.0033 17.8 0.0 0.0079 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 EGG21299.1 - 0.0037 16.4 0.0 0.02 14.0 0.0 1.9 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 TniB PF05621.11 EGG21299.1 - 0.0041 16.6 0.0 1.3 8.4 0.0 2.4 1 1 1 2 2 2 1 Bacterial TniB protein Sigma54_activat PF00158.26 EGG21299.1 - 0.0069 16.1 0.0 0.025 14.3 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EGG21299.1 - 0.0075 15.7 0.2 0.065 12.6 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGG21299.1 - 0.01 16.1 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGG21299.1 - 0.011 15.7 1.1 8.3 6.3 0.0 3.3 3 1 0 3 3 3 0 NTPase DUF815 PF05673.13 EGG21299.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 EGG21299.1 - 0.013 15.4 0.4 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain SKI PF01202.22 EGG21299.1 - 0.021 14.9 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase AAA_7 PF12775.7 EGG21299.1 - 0.023 14.2 0.0 0.052 13.1 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EGG21299.1 - 0.025 14.6 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EGG21299.1 - 0.045 13.7 0.1 0.23 11.3 0.1 2.1 1 1 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 EGG21299.1 - 0.061 13.8 0.0 0.27 11.7 0.0 1.8 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 EGG21299.1 - 0.07 13.0 0.4 0.57 10.0 0.4 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 EGG21299.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase Sigma54_activ_2 PF14532.6 EGG21299.1 - 0.09 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 EGG21299.1 - 0.099 12.0 0.2 0.9 8.8 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.6 EGG21299.1 - 0.1 13.0 0.3 1.5 9.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGG21299.1 - 0.1 12.1 0.2 0.56 9.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGG21299.1 - 0.11 12.3 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IPT PF01745.16 EGG21299.1 - 0.13 11.6 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 Isopentenyl transferase AAA_23 PF13476.6 EGG21299.1 - 1 9.8 4.8 5.4 7.5 3.2 2.9 2 1 0 2 2 2 0 AAA domain ArfGap PF01412.18 EGG21300.1 - 5.5e-22 78.0 1.4 5.5e-22 78.0 1.4 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.29 EGG21300.1 - 1.6e-15 57.5 0.3 1.6e-15 57.5 0.3 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EGG21300.1 - 0.00046 20.6 1.1 0.00046 20.6 1.1 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 EGG21300.1 - 0.0012 18.9 0.2 0.0031 17.6 0.2 1.7 1 0 0 1 1 1 1 PH domain DZR PF12773.7 EGG21300.1 - 0.23 11.5 4.2 2.7 8.1 4.1 2.5 1 1 0 1 1 1 0 Double zinc ribbon MRC1 PF09444.10 EGG21300.1 - 0.3 11.6 2.8 0.23 12.0 0.4 1.9 3 0 0 3 3 3 0 MRC1-like domain Abhydrolase_3 PF07859.13 EGG21302.1 - 1.6e-69 234.0 0.1 3.1e-69 233.0 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold FYVE PF01363.21 EGG21302.1 - 1.1e-19 70.4 14.5 2.4e-19 69.2 14.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger COesterase PF00135.28 EGG21302.1 - 5.6e-11 42.0 2.4 7.1e-11 41.7 0.0 2.2 2 1 0 2 2 2 1 Carboxylesterase family Say1_Mug180 PF10340.9 EGG21302.1 - 0.0028 16.6 0.1 0.014 14.3 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase DLH PF01738.18 EGG21302.1 - 0.0034 17.0 0.0 0.25 10.9 0.0 2.5 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 EGG21302.1 - 0.0077 14.9 0.0 0.017 13.8 0.0 1.5 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EGG21302.1 - 0.018 14.6 0.1 0.018 14.6 0.1 2.9 2 2 1 3 3 3 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGG21302.1 - 0.028 13.7 0.0 0.089 12.0 0.0 1.7 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EGG21302.1 - 0.068 12.7 0.7 0.91 9.0 0.7 2.2 1 1 0 1 1 1 0 Esterase PHB depolymerase TFIIA PF03153.13 EGG21302.1 - 0.13 12.3 23.2 0.18 11.8 23.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dicty_REP PF05086.12 EGG21302.1 - 4.1 5.3 17.5 5.8 4.8 17.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.10 EGG21302.1 - 6.2 5.4 12.1 11 4.6 12.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ank_2 PF12796.7 EGG21303.1 - 3.6e-37 126.8 10.4 2.8e-07 31.0 0.1 8.7 3 2 3 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG21303.1 - 7.2e-24 83.8 14.4 0.0049 17.4 0.1 11.6 7 4 2 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG21303.1 - 7e-21 72.1 18.5 0.73 10.6 0.0 15.2 16 1 1 17 17 17 6 Ankyrin repeat Ank_5 PF13857.6 EGG21303.1 - 7.8e-10 38.8 14.1 1.1 9.7 0.1 12.3 11 4 4 15 15 15 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EGG21303.1 - 0.2 11.7 12.2 4.4 7.3 0.1 6.1 5 3 1 6 6 6 0 Domain of unknown function (DUF3447) Ank PF00023.30 EGG21303.1 - 0.94 10.0 18.5 1.4e+02 3.2 0.0 9.6 7 4 2 9 9 9 0 Ankyrin repeat Podoplanin PF05808.11 EGG21304.1 - 0.01 16.0 0.6 0.022 14.9 0.6 1.6 1 0 0 1 1 1 0 Podoplanin Toxin_5 PF05294.13 EGG21304.1 - 0.22 11.9 4.5 0.59 10.6 4.5 1.7 1 0 0 1 1 1 0 Scorpion short toxin hEGF PF12661.7 EGG21304.1 - 2.4 8.9 13.2 5.9 7.7 13.2 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF Acetyltransf_9 PF13527.7 EGG21305.1 - 3.4e-06 27.2 0.0 2.1e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG21305.1 - 0.0022 18.2 0.0 0.0043 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG21305.1 - 0.024 15.1 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_35 PF14516.6 EGG21306.1 - 6.1e-07 28.6 0.0 1.6e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain ATPase_2 PF01637.18 EGG21306.1 - 0.00011 22.2 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA PF00004.29 EGG21306.1 - 0.0049 17.3 0.0 0.043 14.3 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DER1 PF04511.15 EGG21307.1 - 5.9e-51 173.1 15.4 5.9e-51 173.1 15.4 2.1 2 1 0 2 2 2 1 Der1-like family TMEM52 PF14979.6 EGG21307.1 - 0.12 12.3 6.6 0.07 13.0 4.0 1.9 2 0 0 2 2 2 0 Transmembrane 52 DUF5316 PF17247.2 EGG21307.1 - 0.41 10.7 4.7 14 5.7 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5316) CCER1 PF15482.6 EGG21307.1 - 1.7 8.5 5.9 3.1 7.6 5.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 DUF4133 PF13571.6 EGG21307.1 - 3.8 7.9 7.6 0.79 10.1 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4133) STT3 PF02516.14 EGG21308.1 - 2.2e-123 412.8 42.4 5.2e-119 398.4 38.1 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit C2 PF00168.30 EGG21310.1 - 2.6e-09 37.3 0.0 4.7e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain TFIIS_C PF01096.18 EGG21311.1 - 8e-10 38.4 3.1 8e-10 38.4 3.1 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGG21311.1 - 0.00034 20.4 3.7 0.0065 16.3 0.1 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Terminase_GpA PF05876.12 EGG21311.1 - 0.008 14.8 0.5 0.0092 14.6 0.5 1.1 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Peptidase_C93 PF06035.11 EGG21311.1 - 0.04 13.7 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP zf-RRPl_C4 PF17026.5 EGG21311.1 - 0.13 12.4 4.1 0.35 11.0 4.1 1.8 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-Mss51 PF13824.6 EGG21311.1 - 0.64 10.2 5.2 6.6 6.9 0.2 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_4 PF13717.6 EGG21311.1 - 0.72 9.8 5.8 11 6.0 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 EGG21311.1 - 0.91 9.3 6.7 14 5.5 3.3 2.9 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 PF12760.7 EGG21311.1 - 1.8 8.6 7.7 0.13 12.2 1.5 2.1 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 EGG21311.1 - 2.7 8.6 10.8 13 6.4 1.2 3.2 3 0 0 3 3 3 0 Zinc-finger double domain PIG-U PF06728.13 EGG21312.1 - 2e-108 362.9 46.0 2.9e-108 362.3 46.0 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Orf78 PF06024.12 EGG21312.1 - 0.021 15.1 3.0 0.021 15.1 3.0 3.7 4 0 0 4 4 4 0 Orf78 (ac78) DUF5113 PF17140.4 EGG21312.1 - 0.52 10.1 7.6 0.16 11.8 2.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5113) TMEM154 PF15102.6 EGG21312.1 - 3.2 7.6 7.1 1.4 8.8 0.1 2.9 3 0 0 3 3 3 0 TMEM154 protein family CorA PF01544.18 EGG21313.1 - 5e-45 154.0 2.5 5e-45 154.0 2.5 2.2 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein DUF3439 PF11921.8 EGG21313.1 - 0.072 13.0 6.6 0.2 11.6 6.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SOG2 PF10428.9 EGG21313.1 - 0.47 9.6 14.3 0.021 14.1 9.0 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein Dicty_CAD PF05720.12 EGG21314.1 - 3.5e-15 55.7 0.0 4.3e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Cell-cell adhesion domain TRAPPC10 PF12584.8 EGG21315.1 - 3e-10 40.0 0.1 1e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 EGG21315.1 - 3.3e-05 23.6 0.2 8.7e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Foie gras liver health family 1 AMPK1_CBM PF16561.5 EGG21316.1 - 4.3e-35 119.8 0.1 2.3e-34 117.4 0.2 2.3 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EGG21316.1 - 3e-21 75.4 5.9 9.2e-21 73.9 5.9 1.9 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain fn3 PF00041.21 EGG21316.1 - 7.4e-10 39.0 50.4 0.017 15.4 0.6 10.0 11 0 0 11 11 11 5 Fibronectin type III domain EGF_2 PF07974.13 EGG21316.1 - 0.00086 19.6 11.5 0.0031 17.9 11.5 2.1 1 0 0 1 1 1 1 EGF-like domain CBM_48 PF02922.18 EGG21316.1 - 0.0079 16.5 0.1 0.04 14.3 0.1 2.2 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) GalBD_like PF17974.1 EGG21316.1 - 0.093 12.9 0.9 17 5.5 0.1 2.6 2 0 0 2 2 2 0 Galactose-binding domain-like Trp_oprn_chp PF09534.10 EGG21316.1 - 0.24 11.2 2.1 19 5.0 0.1 3.3 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF742 PF05331.11 EGG21316.1 - 2.1 8.2 5.4 19 5.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF742) MNHE PF01899.16 EGG21316.1 - 3.7 7.3 8.0 7.3 6.3 1.0 3.1 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit EGF PF00008.27 EGG21316.1 - 7.5 7.0 12.8 1.1 9.6 7.0 2.9 2 0 0 2 2 2 0 EGF-like domain TFIIIC_sub6 PF10419.9 EGG21317.1 - 1.2e-14 53.9 0.1 2.5e-14 52.9 0.0 1.7 1 1 0 1 1 1 1 TFIIIC subunit triple barrel domain Chlam_PMP PF02415.17 EGG21319.1 - 0.1 13.1 0.7 0.1 13.1 0.7 6.6 6 1 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Peptidase_M4 PF01447.18 EGG21319.1 - 0.1 13.1 4.9 0.26 11.8 4.9 1.7 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain PgaD PF13994.6 EGG21320.1 - 0.087 12.9 0.8 0.3 11.1 0.8 1.9 1 0 0 1 1 1 0 PgaD-like protein PHM7_cyt PF14703.6 EGG21320.1 - 0.19 12.0 2.0 3 8.0 2.0 2.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF4502 PF14950.6 EGG21320.1 - 2.2 7.6 6.5 1.1 8.6 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4502) DUF3917 PF13055.6 EGG21320.1 - 8.9 6.8 9.7 0.5 10.8 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3917) DUF3808 PF10300.9 EGG21321.1 - 9.2e-47 159.9 3.7 9.2e-47 159.9 3.7 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 EGG21321.1 - 7.2e-08 32.6 0.2 0.39 11.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG21321.1 - 3.2e-07 30.0 0.6 12 6.3 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG21321.1 - 9.3e-06 26.0 0.3 1.8 9.4 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG21321.1 - 0.00083 19.8 0.0 0.16 12.5 0.0 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG21321.1 - 0.0038 17.0 3.0 12 5.9 0.0 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG21321.1 - 0.0053 17.0 7.9 0.16 12.2 0.1 4.6 4 2 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EGG21321.1 - 0.088 13.1 0.2 0.088 13.1 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Rrn6 PF10214.9 EGG21323.1 - 1.2 7.6 34.9 1.4 7.3 34.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor LAP1C PF05609.12 EGG21323.1 - 1.9 7.5 20.4 2.6 7.1 20.4 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) AF-4 PF05110.13 EGG21323.1 - 8.4 4.3 53.2 11 3.9 53.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Branch PF02485.21 EGG21324.1 - 6.2e-06 25.9 0.2 8.9e-06 25.4 0.2 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF1131 PF06572.12 EGG21324.1 - 0.031 14.0 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) PAPS_reduct PF01507.19 EGG21324.1 - 0.098 12.7 0.1 0.19 11.7 0.1 1.5 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family NDK PF00334.19 EGG21325.1 - 5.2e-31 107.5 0.0 6.2e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_35 PF01301.19 EGG21326.1 - 4.3e-101 338.7 7.3 7e-101 338.0 7.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Cellulase PF00150.18 EGG21326.1 - 4.3e-05 23.1 0.7 9e-05 22.0 0.6 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mpv17_PMP22 PF04117.12 EGG21327.1 - 4.4e-23 81.3 1.8 5.2e-23 81.0 0.8 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family IF-2 PF11987.8 EGG21328.1 - 4.7e-12 46.0 1.6 1.7e-10 41.0 0.0 2.7 3 0 0 3 3 3 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EGG21328.1 - 8.5e-06 26.1 1.0 2.4e-05 24.7 1.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EGG21328.1 - 6.6e-05 22.7 1.7 0.00016 21.5 1.7 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Fer2_BFD PF04324.15 EGG21328.1 - 0.023 15.0 1.9 4.1 7.8 0.0 3.0 3 1 0 3 3 3 0 BFD-like [2Fe-2S] binding domain GTP_EFTU PF00009.27 EGG21329.1 - 0.033 13.7 10.0 0.64 9.5 0.0 3.8 3 1 1 4 4 4 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 EGG21329.1 - 4.4 6.2 6.6 4.3 6.2 0.0 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Complex1_LYR_2 PF13233.6 EGG21330.1 - 9.6e-14 51.9 0.7 1.4e-13 51.4 0.7 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGG21330.1 - 5.9e-06 26.2 0.2 1.1e-05 25.4 0.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Cyt-b5 PF00173.28 EGG21331.1 - 2.9e-20 72.2 0.0 4.1e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TarS_C1 PF18674.1 EGG21331.1 - 0.075 13.0 0.3 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 TarS beta-glycosyltransferase C-terminal domain 1 DUF2135 PF09906.9 EGG21332.1 - 4.7e-13 49.2 0.6 2e-12 47.2 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2135) SAP PF02037.27 EGG21332.1 - 0.00012 21.7 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 SAP domain CarboxypepD_reg PF13620.6 EGG21333.1 - 0.012 15.9 0.9 1.7 9.0 0.1 3.3 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Staygreen PF12638.7 EGG21334.1 - 0.0021 17.9 0.1 0.0027 17.5 0.1 1.3 1 0 0 1 1 1 1 Staygreen protein YiiD_C PF09500.10 EGG21334.1 - 0.013 15.4 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) Dsl1_C PF11989.8 EGG21334.1 - 0.063 13.0 0.2 0.1 12.3 0.1 1.4 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 C terminal Glyco_hydro_30C PF17189.4 EGG21334.1 - 0.29 11.4 3.1 0.75 10.1 0.3 2.5 3 0 0 3 3 3 0 Glycosyl hydrolase family 30 beta sandwich domain Colicin_E5 PF12106.8 EGG21334.1 - 1.2 9.5 3.5 1.5 9.1 2.0 1.9 1 1 1 2 2 2 0 Colicin E5 ribonuclease domain Ank_2 PF12796.7 EGG21336.1 - 2.3e-10 40.9 1.0 0.00084 19.9 0.0 5.1 3 1 3 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG21336.1 - 7.4e-06 25.9 0.2 29 5.7 0.0 6.9 8 0 0 8 8 8 1 Ankyrin repeat Ank_4 PF13637.6 EGG21336.1 - 4.2e-05 24.0 1.5 2.5 8.8 0.0 6.0 6 1 0 6 6 6 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG21336.1 - 0.0018 18.5 0.6 61 4.1 0.0 5.1 4 2 1 5 5 5 0 Ankyrin repeats (many copies) DUF3447 PF11929.8 EGG21336.1 - 0.26 11.3 0.0 0.26 11.3 0.0 5.2 4 1 2 6 6 6 0 Domain of unknown function (DUF3447) Ribosomal_L19e PF01280.20 EGG21337.1 - 6.3e-13 49.0 0.0 8.3e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e DHQ_synthase PF01761.20 EGG21337.1 - 0.15 11.2 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase Peptidase_C1 PF00112.23 EGG21338.1 - 1e-76 257.9 9.0 1.6e-76 257.2 9.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG21338.1 - 8.3e-14 51.8 4.4 1.5e-13 51.0 4.4 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGG21338.1 - 9.8e-05 21.3 1.7 0.037 12.8 0.3 2.3 2 0 0 2 2 2 2 Peptidase C1-like family AF-4 PF05110.13 EGG21338.1 - 1.5 6.8 6.9 2 6.4 6.9 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein WD40 PF00400.32 EGG21339.1 - 1.2e-29 101.9 11.6 4.5e-07 30.5 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Mpp10 PF04006.12 EGG21339.1 - 0.0008 18.0 41.9 0.0008 18.0 41.9 2.1 2 0 0 2 2 2 1 Mpp10 protein ANAPC4_WD40 PF12894.7 EGG21339.1 - 0.0035 17.6 0.0 0.53 10.6 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain FSA_C PF10479.9 EGG21339.1 - 0.11 10.6 12.9 0.2 9.8 12.9 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SSP160 PF06933.11 EGG21339.1 - 1.3 7.1 25.7 2.1 6.4 25.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BAP PF06639.11 EGG21339.1 - 1.4 9.3 5.4 4.4 7.7 5.4 1.9 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) DUF572 PF04502.13 EGG21339.1 - 1.6 8.3 35.8 3.3 7.2 17.2 3.9 4 0 0 4 4 4 0 Family of unknown function (DUF572) Trp_dioxygenase PF03301.13 EGG21340.1 - 6.6e-114 380.8 3.9 8e-114 380.6 3.9 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase CENP-S PF15630.6 EGG21341.1 - 4.2e-24 84.7 0.8 8.8e-24 83.7 0.8 1.6 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGG21341.1 - 5e-06 26.6 0.9 1.1e-05 25.5 0.9 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF4037 PF13228.6 EGG21341.1 - 0.16 12.8 0.2 0.32 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) DUF829 PF05705.14 EGG21342.1 - 5.6e-41 141.0 0.1 8.6e-41 140.4 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.21 EGG21342.1 - 0.018 14.5 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PEMT PF04191.13 EGG21343.1 - 1.6e-55 186.0 10.1 4.3e-33 113.9 2.1 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase TPR_1 PF00515.28 EGG21343.1 - 5.8e-24 82.9 6.1 2.1e-06 27.3 0.2 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGG21343.1 - 3.2e-18 64.3 3.9 9.5e-05 22.2 0.3 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGG21343.1 - 2.7e-14 52.5 0.2 0.0045 16.7 0.0 5.2 4 1 1 5 5 5 3 TPR repeat TPR_17 PF13431.6 EGG21343.1 - 3.1e-12 46.0 4.1 0.01 16.1 0.1 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG21343.1 - 4.9e-12 45.1 0.6 0.016 15.4 0.1 5.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG21343.1 - 7.8e-09 36.0 0.5 2.8e-06 27.9 0.2 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGG21343.1 - 8.5e-07 29.0 0.1 0.064 13.4 0.3 3.7 1 1 3 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG21343.1 - 5e-05 23.4 0.2 0.54 10.5 0.3 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EGG21343.1 - 7.7e-05 23.2 1.3 0.89 10.5 0.0 3.8 4 1 1 5 5 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG21343.1 - 8.3e-05 22.8 0.3 0.2 12.0 0.0 3.8 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG21343.1 - 0.00032 21.2 0.1 0.47 11.0 0.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG21343.1 - 0.0044 17.6 0.9 2 9.2 0.2 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGG21343.1 - 0.0085 15.5 0.0 1.8 8.1 0.0 3.0 2 0 0 2 2 2 1 SHNi-TPR TPR_7 PF13176.6 EGG21343.1 - 0.032 14.3 1.5 18 5.7 0.3 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EGG21343.1 - 0.087 12.8 0.1 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Putative TPR-like repeat HU-DNA_bdg PF14848.6 EGG21343.1 - 0.19 11.7 0.9 0.36 10.8 0.2 1.7 2 0 0 2 2 2 0 DNA-binding domain SR-25 PF10500.9 EGG21343.1 - 2.6 7.6 33.7 0.87 9.2 12.5 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TPR_1 PF00515.28 EGG21344.1 - 4.5e-09 35.7 0.2 3.4e-05 23.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG21344.1 - 5.3e-06 26.1 0.0 0.017 15.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG21344.1 - 3.8e-05 23.7 0.1 0.16 12.0 0.0 2.5 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EGG21344.1 - 0.0013 18.8 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-U1 PF06220.12 EGG21345.1 - 2.6e-07 30.3 1.2 4.4e-07 29.6 1.2 1.4 1 0 0 1 1 1 1 U1 zinc finger Pkinase PF00069.25 EGG21346.1 - 1.5e-71 240.9 0.1 1.5e-71 240.9 0.1 2.1 2 0 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21346.1 - 5.2e-31 107.9 0.0 5.2e-31 107.9 0.0 2.0 2 0 0 2 2 1 1 Protein tyrosine kinase Ndc1_Nup PF09531.10 EGG21346.1 - 0.0091 14.7 9.8 0.014 14.2 9.8 1.3 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DDHD PF02862.17 EGG21346.1 - 0.78 9.9 18.7 0.06 13.5 12.5 2.0 2 0 0 2 2 2 0 DDHD domain Cellulose_synt PF03552.14 EGG21346.1 - 1 7.8 3.9 1.3 7.4 3.9 1.2 1 0 0 1 1 1 0 Cellulose synthase TFIIA PF03153.13 EGG21346.1 - 1.1 9.2 60.4 0.69 9.9 48.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 EGG21346.1 - 1.7 8.1 21.2 0.013 15.1 12.2 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4746 PF15928.5 EGG21346.1 - 1.8 7.9 11.1 3.4 7.0 11.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Membralin PF09746.9 EGG21346.1 - 2.7 7.0 13.9 27 3.6 13.1 2.3 2 0 0 2 2 2 0 Tumour-associated protein V_ATPase_I PF01496.19 EGG21346.1 - 2.7 5.8 16.5 5.3 4.8 16.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rtf2 PF04641.12 EGG21346.1 - 3 7.1 15.9 24 4.2 16.8 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger Connexin PF00029.19 EGG21346.1 - 4 7.1 9.0 7.6 6.2 9.0 1.4 1 0 0 1 1 1 0 Connexin DUF4407 PF14362.6 EGG21346.1 - 4 6.7 23.6 0.18 11.1 15.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) LicD PF04991.13 EGG21346.1 - 4.1 7.5 9.8 2.6 8.1 4.3 2.7 3 0 0 3 3 3 0 LicD family Zip PF02535.22 EGG21346.1 - 4.3 6.5 5.1 7 5.8 5.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PepSY_TM PF03929.16 EGG21346.1 - 7.7 6.1 13.0 0.61 9.7 7.9 1.7 2 0 0 2 2 2 0 PepSY-associated TM region Amidase PF01425.21 EGG21347.1 - 1.6e-132 442.7 1.5 4.8e-132 441.1 1.5 1.6 1 1 0 1 1 1 1 Amidase WD40 PF00400.32 EGG21348.1 - 2.5e-13 50.2 10.1 0.0041 17.9 0.3 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40_like PF17005.5 EGG21348.1 - 4.3e-07 29.5 1.8 4.3e-07 29.5 1.8 1.8 2 1 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 EGG21348.1 - 3.7e-06 27.2 2.0 0.078 13.3 0.0 4.3 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 EGG21348.1 - 0.024 13.9 0.3 0.2 10.9 0.0 2.2 1 1 0 2 2 2 0 CPSF A subunit region TRAP-delta PF05404.12 EGG21348.1 - 0.07 12.7 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) PRK PF00485.18 EGG21349.1 - 3.5e-07 30.1 0.0 4.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Ploopntkinase3 PF18751.1 EGG21349.1 - 0.0004 20.3 0.0 0.001 19.1 0.0 1.6 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 EGG21349.1 - 0.00057 20.1 0.2 0.007 16.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG21349.1 - 0.00078 20.0 0.1 0.0038 17.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGG21349.1 - 0.00098 19.4 0.0 0.0018 18.5 0.0 1.6 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.22 EGG21349.1 - 0.0015 17.8 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain MMR_HSR1 PF01926.23 EGG21349.1 - 0.0016 18.5 0.0 0.0034 17.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGG21349.1 - 0.0021 18.6 0.0 0.0039 17.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter MeaB PF03308.16 EGG21349.1 - 0.0021 17.1 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 EGG21349.1 - 0.0086 16.3 0.0 0.022 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGG21349.1 - 0.0099 16.3 0.0 0.016 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EGG21349.1 - 0.013 14.8 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 EGG21349.1 - 0.018 15.4 0.0 0.044 14.2 0.0 1.7 2 0 0 2 2 1 0 RNA helicase DUF2075 PF09848.9 EGG21349.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 EGG21349.1 - 0.033 14.1 0.0 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 EGG21349.1 - 0.035 13.6 0.1 0.053 13.0 0.1 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ResIII PF04851.15 EGG21349.1 - 0.036 14.1 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_17 PF13207.6 EGG21349.1 - 0.054 13.9 0.0 0.5 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGG21349.1 - 0.1 12.5 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 EGG21349.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_25 PF13481.6 EGG21349.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGG21349.1 - 0.21 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Methyltransf_11 PF08241.12 EGG21351.1 - 4.1e-18 65.8 0.1 7.1e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG21351.1 - 3.1e-16 59.9 0.0 6.9e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG21351.1 - 4e-14 52.5 0.0 2.3e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGG21351.1 - 1.2e-12 47.8 0.0 2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG21351.1 - 7.1e-12 45.5 0.0 1e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG21351.1 - 5.2e-08 33.5 0.0 8.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGG21351.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 EGG21351.1 - 0.023 14.3 0.0 0.05 13.2 0.0 1.6 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW NodS PF05401.11 EGG21351.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.19 EGG21351.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AIM5 PF17050.5 EGG21352.1 - 8 7.4 7.7 2.7e+02 2.5 7.7 2.9 1 1 0 1 1 1 0 Altered inheritance of mitochondria 5 EphA2_TM PF14575.6 EGG21354.1 - 0.09 13.7 0.3 7 7.6 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2615 PF11027.8 EGG21354.1 - 0.63 10.2 3.1 1.3 9.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) PH_10 PF15411.6 EGG21354.1 - 1.5 9.1 5.5 46 4.3 0.0 2.7 2 1 1 3 3 3 0 Pleckstrin homology domain GCFC PF07842.12 EGG21355.1 - 8.8e-18 64.9 5.1 6.6e-17 62.0 4.1 2.7 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein Thioredoxin PF00085.20 EGG21355.1 - 0.041 13.9 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin OST3_OST6 PF04756.13 EGG21356.1 - 4.1e-45 154.4 4.0 6.7e-45 153.7 4.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Rad17 PF03215.15 EGG21356.1 - 2.4e-29 102.6 0.2 2.1e-28 99.5 0.1 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGG21356.1 - 0.00011 22.1 0.1 0.00011 22.1 0.1 2.3 2 1 0 2 2 1 1 RsgA GTPase DUF4131 PF13567.6 EGG21356.1 - 0.0006 19.5 6.4 0.0015 18.2 0.5 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4131) AAA_assoc_2 PF16193.5 EGG21356.1 - 0.0043 17.4 0.0 0.013 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain DUF5518 PF17647.1 EGG21356.1 - 0.047 13.8 2.4 0.13 12.5 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5518) AAA_22 PF13401.6 EGG21356.1 - 0.054 13.8 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG21356.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain FDX-ACB PF03147.14 EGG21356.1 - 0.12 12.8 0.0 0.36 11.3 0.0 1.8 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain ABC_tran PF00005.27 EGG21356.1 - 0.17 12.4 0.1 0.17 12.4 0.1 3.7 4 0 0 4 4 4 0 ABC transporter DUF2254 PF10011.9 EGG21356.1 - 0.21 10.3 0.5 0.55 9.0 0.5 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF4064 PF13273.6 EGG21356.1 - 0.55 10.5 10.9 0.37 11.1 0.1 3.8 2 1 1 3 3 2 0 Protein of unknown function (DUF4064) 7TM-7TMR_HD PF07698.11 EGG21356.1 - 1 9.1 8.8 1.7 8.4 3.0 2.4 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase ABC2_membrane_5 PF13346.6 EGG21356.1 - 3.5 7.1 9.5 9.6 5.7 9.5 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein MFS_1 PF07690.16 EGG21356.1 - 4.2 6.2 11.5 1.9 7.3 8.5 1.7 1 1 1 2 2 2 0 Major Facilitator Superfamily AAA_18 PF13238.6 EGG21356.1 - 8.7 6.9 8.1 11 6.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain FtsX PF02687.21 EGG21356.1 - 9.1 6.8 6.9 0.47 11.0 1.2 1.8 2 0 0 2 2 1 0 FtsX-like permease family Bax1-I PF01027.20 EGG21357.1 - 1.2e-36 126.5 21.9 1.5e-36 126.2 21.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2569 PF10754.9 EGG21357.1 - 5.7 7.4 13.1 0.52 10.8 4.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) SH3BGR PF04908.15 EGG21358.1 - 3.4e-14 52.8 0.2 5.2e-14 52.2 0.2 1.3 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 EGG21358.1 - 1.1e-10 41.6 0.0 1.8e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Flg_hook PF02120.16 EGG21358.1 - 0.039 13.8 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK PBECR3 PF18812.1 EGG21358.1 - 0.1 12.6 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 GST_N PF02798.20 EGG21358.1 - 0.16 12.3 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGG21358.1 - 0.17 12.4 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain BAR_3 PF16746.5 EGG21359.1 - 1.2e-16 61.1 7.1 2.4e-16 60.2 5.8 1.9 2 0 0 2 2 2 1 BAR domain of APPL family BAR PF03114.18 EGG21359.1 - 2.9e-10 40.2 5.6 4.5e-10 39.6 5.6 1.2 1 0 0 1 1 1 1 BAR domain RhoGAP PF00620.27 EGG21359.1 - 2.7e-07 30.5 1.1 0.00048 20.0 0.0 3.1 2 1 1 3 3 3 2 RhoGAP domain BAR_2 PF10455.9 EGG21359.1 - 0.0013 17.9 6.9 0.0024 17.0 6.9 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4208 PF13907.6 EGG21359.1 - 0.04 14.3 0.1 0.04 14.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) IMD PF08397.11 EGG21359.1 - 0.35 10.2 7.8 0.29 10.5 2.1 2.3 2 0 0 2 2 2 0 IRSp53/MIM homology domain DUF643 PF04867.12 EGG21359.1 - 0.48 11.1 4.7 1.4 9.6 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF643) DUF3987 PF13148.6 EGG21359.1 - 9.3 5.2 5.9 0.61 9.0 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) CNOT11 PF10155.9 EGG21360.1 - 6.9e-46 155.5 7.5 2e-45 154.0 7.5 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 TT_ORF1 PF02956.14 EGG21360.1 - 3 6.4 11.9 4.2 5.9 11.9 1.1 1 0 0 1 1 1 0 TT viral orf 1 Pterin_4a PF01329.19 EGG21361.1 - 6.7e-09 35.8 0.0 9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Transp_cyt_pur PF02133.15 EGG21362.1 - 0.022 13.5 1.9 0.026 13.3 1.9 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin TIP49 PF06068.13 EGG21364.1 - 5.3e-154 512.6 3.5 7.3e-154 512.2 3.5 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGG21364.1 - 1.4e-26 92.3 1.4 3.3e-26 91.2 0.6 2.1 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 EGG21364.1 - 3e-09 37.4 0.2 3e-05 24.5 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGG21364.1 - 2.7e-08 33.7 0.9 0.00055 19.7 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGG21364.1 - 4.8e-06 26.9 0.0 0.013 15.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGG21364.1 - 9.6e-06 26.1 0.2 3.3e-05 24.3 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 EGG21364.1 - 1.2e-05 24.8 0.1 1.9e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 EGG21364.1 - 4.2e-05 23.3 0.2 0.034 13.8 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 EGG21364.1 - 4.4e-05 23.5 0.3 0.072 13.1 0.0 2.8 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EGG21364.1 - 0.0011 19.3 2.9 0.031 14.6 2.9 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGG21364.1 - 0.0012 18.3 1.3 0.081 12.3 0.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EGG21364.1 - 0.0063 15.9 0.1 0.013 14.9 0.1 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 EGG21364.1 - 0.0085 15.7 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 EGG21364.1 - 0.023 13.9 0.8 2.8 7.0 0.2 2.2 2 0 0 2 2 2 0 PIF1-like helicase DUF2075 PF09848.9 EGG21364.1 - 0.029 13.6 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 EGG21364.1 - 0.034 13.4 0.4 0.072 12.4 0.4 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 EGG21364.1 - 0.034 13.6 0.3 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 EGG21364.1 - 0.036 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 EGG21364.1 - 0.081 12.9 0.2 4.3 7.3 0.1 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EGG21364.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGG21364.1 - 0.11 12.5 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EGG21364.1 - 0.14 12.6 1.9 0.41 11.1 0.1 2.7 3 1 1 4 4 2 0 AAA domain Radical_SAM PF04055.21 EGG21365.1 - 3.2e-31 109.0 0.1 5.7e-31 108.1 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 EGG21365.1 - 4.7e-29 100.3 0.2 1.1e-28 99.2 0.2 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 EGG21365.1 - 6.6e-07 29.2 0.0 1.8e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 TRAM domain Palm_thioest PF02089.15 EGG21366.1 - 5.7e-85 285.0 0.5 1e-84 284.2 0.0 1.7 2 0 0 2 2 2 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EGG21366.1 - 0.011 15.1 0.5 0.06 12.7 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) ChAPs PF09295.10 EGG21367.1 - 2.5e-40 138.7 0.0 7.1e-40 137.2 0.0 1.8 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 EGG21367.1 - 5.2e-05 23.7 0.0 0.0057 17.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGG21367.1 - 0.00034 19.9 0.0 0.00077 18.8 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG21367.1 - 0.0018 18.2 0.0 7.7 6.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG21367.1 - 0.0046 17.4 0.1 0.021 15.3 0.1 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG21367.1 - 0.007 16.6 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Macoilin PF09726.9 EGG21367.1 - 2.1 6.8 18.6 3.4 6.1 18.6 1.2 1 0 0 1 1 1 0 Macoilin family DSPc PF00782.20 EGG21368.1 - 2.1e-33 115.0 0.0 2.1e-33 115.0 0.0 2.6 2 0 0 2 2 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 EGG21368.1 - 1.2e-24 85.8 24.9 3e-08 33.3 1.0 5.6 1 1 6 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 EGG21368.1 - 9e-12 45.0 53.0 8.7e-06 26.0 2.3 7.1 4 1 2 6 6 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGG21368.1 - 5.4e-07 29.3 15.7 5.4e-05 22.8 0.4 3.7 1 1 3 4 4 4 2 Leucine-rich repeat Y_phosphatase PF00102.27 EGG21368.1 - 0.00053 19.6 0.0 0.00053 19.6 0.0 2.1 2 0 0 2 2 1 1 Protein-tyrosine phosphatase LRR_6 PF13516.6 EGG21368.1 - 0.041 13.9 28.7 5 7.4 0.6 8.4 9 0 0 9 9 8 0 Leucine Rich repeat SDA1 PF05285.12 EGG21368.1 - 0.11 11.9 6.6 0.16 11.3 6.6 1.1 1 0 0 1 1 1 0 SDA1 LRR_2 PF07723.13 EGG21368.1 - 0.22 12.2 4.1 15 6.5 0.1 4.8 4 1 1 5 5 5 0 Leucine Rich Repeat Dapper PF15268.6 EGG21368.1 - 0.78 8.5 8.0 1.1 8.0 8.0 1.1 1 0 0 1 1 1 0 Dapper DUF2981 PF11200.8 EGG21368.1 - 1.5 8.5 12.4 2.8 7.6 12.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Presenilin PF01080.17 EGG21368.1 - 1.8 7.3 13.0 2.9 6.6 13.0 1.3 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EGG21368.1 - 2.4 7.3 6.2 4.3 6.5 6.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FAM196 PF15265.6 EGG21368.1 - 4.4 6.7 16.6 6.5 6.1 16.6 1.2 1 0 0 1 1 1 0 FAM196 family SOG2 PF10428.9 EGG21368.1 - 4.6 6.3 20.2 8.3 5.5 20.2 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Sel1 PF08238.12 EGG21370.1 - 2.7e-11 43.8 23.7 7.1e-05 23.3 0.0 8.5 9 1 0 9 9 9 4 Sel1 repeat Mor PF08765.11 EGG21370.1 - 0.073 13.1 0.0 0.28 11.2 0.0 2.0 1 0 0 1 1 1 0 Mor transcription activator family Kinesin PF00225.23 EGG21371.1 - 3e-100 335.4 27.2 3e-100 335.4 27.2 5.8 5 2 0 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 EGG21371.1 - 2.4e-23 82.7 1.3 2.4e-23 82.7 1.3 5.7 6 2 0 6 6 6 1 Microtubule binding RL10P_insert PF17777.1 EGG21371.1 - 0.85 9.7 4.9 0.93 9.5 0.2 3.7 3 0 0 3 3 3 0 Insertion domain in 60S ribosomal protein L10P Dak2 PF02734.17 EGG21371.1 - 1.1 9.1 6.7 0.11 12.4 0.3 2.8 3 0 0 3 3 3 0 DAK2 domain DNA_pol_A PF00476.20 EGG21372.1 - 4.3e-81 272.9 1.0 4.3e-81 272.9 1.0 2.8 2 1 0 2 2 2 1 DNA polymerase family A DNA_pol_P_Exo PF18049.1 EGG21372.1 - 0.002 17.5 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase nu pseudo-exo BTB PF00651.31 EGG21374.1 - 1.5e-20 73.5 1.8 1.1e-16 61.0 0.2 3.2 2 1 1 3 3 3 2 BTB/POZ domain BACK PF07707.15 EGG21374.1 - 8.9e-11 41.8 1.5 3.2e-08 33.6 0.9 3.3 2 1 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 EGG21374.1 - 0.0016 18.6 0.0 0.0016 18.6 0.0 1.7 2 0 0 2 2 2 1 F5/8 type C domain CDC45 PF02724.14 EGG21374.1 - 6.7 4.9 10.4 8.9 4.5 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Roc PF08477.13 EGG21375.1 - 7.1e-05 23.0 0.1 0.00012 22.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG21375.1 - 0.00015 21.5 0.1 0.00019 21.0 0.1 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 EGG21375.1 - 0.0039 16.7 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG21375.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGG21375.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EGG21375.1 - 0.03 13.8 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EGG21375.1 - 0.031 13.9 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGG21375.1 - 0.037 14.1 0.0 0.063 13.4 0.0 1.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.20 EGG21375.1 - 0.044 12.9 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Septin PF00735.18 EGG21375.1 - 0.073 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 EGG21375.1 - 0.087 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 EGG21375.1 - 0.089 11.6 0.0 0.092 11.6 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) TniB PF05621.11 EGG21375.1 - 0.093 12.1 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 EGG21375.1 - 0.095 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.22 EGG21376.1 - 2.3e-15 56.6 0.2 3e-15 56.2 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG21376.1 - 7.3e-13 48.8 0.3 1.4e-12 47.8 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG21376.1 - 1.3e-10 41.0 0.5 1.9e-10 40.5 0.5 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG21376.1 - 5.3e-05 22.8 0.1 6.7e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGG21376.1 - 0.0001 21.8 0.6 0.00014 21.3 0.3 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF2443 PF10398.9 EGG21376.1 - 0.023 14.7 2.0 0.19 11.8 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2443) Sulfotransfer_2 PF03567.14 EGG21377.1 - 3.6e-08 33.6 0.5 3.6e-08 33.6 0.5 3.0 3 1 0 3 3 3 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 EGG21377.1 - 0.00054 19.0 0.2 0.021 13.7 0.1 2.3 2 0 0 2 2 2 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.27 EGG21377.1 - 0.058 12.9 1.9 0.075 12.5 0.1 2.1 2 1 0 2 2 2 0 Sulfotransferase domain AAA_23 PF13476.6 EGG21377.1 - 0.44 11.0 12.9 2.7 8.4 1.3 2.4 2 0 0 2 2 2 0 AAA domain RIC3 PF15361.6 EGG21377.1 - 3.5 8.0 7.7 10 6.5 2.8 2.6 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 TolA_bind_tri PF16331.5 EGG21377.1 - 4.2 7.5 15.0 0.12 12.5 7.9 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation SlyX PF04102.12 EGG21377.1 - 7.3 7.3 16.2 5.8 7.6 10.8 3.1 2 1 1 3 3 3 0 SlyX Iso_dh PF00180.20 EGG21379.1 - 1.3e-77 261.3 0.0 1.9e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CBFD_NFYB_HMF PF00808.23 EGG21379.1 - 1.9e-11 44.1 0.0 4.3e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DHHW PF14286.6 EGG21379.1 - 0.037 13.3 1.1 0.059 12.7 1.1 1.3 1 0 0 1 1 1 0 DHHW protein Vasculin PF15337.6 EGG21379.1 - 0.051 14.4 2.4 4.5 8.2 2.5 2.4 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 Striatin PF08232.12 EGG21379.1 - 0.13 12.9 2.7 0.23 12.1 2.7 1.3 1 0 0 1 1 1 0 Striatin family FNIP PF05725.12 EGG21380.1 - 5.7e-11 42.4 12.5 0.022 14.9 0.0 7.8 6 2 0 7 7 7 4 FNIP Repeat Apis_Csd PF11671.8 EGG21380.1 - 7.2 6.6 8.9 16 5.5 4.5 2.9 3 0 0 3 3 3 0 Complementary sex determiner protein Apc15p PF05841.11 EGG21380.1 - 9.1 7.1 11.8 24 5.8 2.6 3.0 3 0 0 3 3 3 0 Apc15p protein SelR PF01641.18 EGG21381.1 - 1.2e-52 177.1 1.0 2.5e-52 176.0 0.1 1.8 2 0 0 2 2 2 1 SelR domain GFA PF04828.14 EGG21381.1 - 0.002 18.4 0.9 1.6 9.1 0.0 2.8 1 1 2 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Cypo_polyhedrin PF05865.11 EGG21381.1 - 0.014 14.9 3.9 0.02 14.3 3.9 1.2 1 0 0 1 1 1 0 Cypovirus polyhedrin protein zinc_ribbon_10 PF10058.9 EGG21381.1 - 0.021 14.5 0.3 0.48 10.2 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Mss51 PF13824.6 EGG21381.1 - 0.11 12.6 2.1 0.68 10.1 0.3 2.6 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 RIG-I_C-RD PF11648.8 EGG21381.1 - 0.13 12.5 1.2 0.79 10.0 0.1 2.3 2 0 0 2 2 2 0 C-terminal domain of RIG-I DZR PF12773.7 EGG21381.1 - 0.13 12.3 1.9 1.4 9.0 1.3 2.3 1 1 2 3 3 3 0 Double zinc ribbon Yippee-Mis18 PF03226.14 EGG21381.1 - 0.46 10.7 3.7 0.86 9.8 0.3 2.6 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_15 PF17032.5 EGG21381.1 - 1.2 9.9 5.0 5.1 7.9 2.3 2.3 2 1 0 2 2 2 0 zinc-ribbon family CLP1_P PF16575.5 EGG21382.1 - 2.6e-64 216.5 0.0 6.8e-64 215.1 0.0 1.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EGG21382.1 - 7.5e-32 110.2 0.0 1.2e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 EGG21382.1 - 1.7e-27 95.5 0.1 2.7e-27 94.8 0.1 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor MMR_HSR1 PF01926.23 EGG21382.1 - 0.024 14.7 0.1 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EGG21382.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain Asp PF00026.23 EGG21383.1 - 8.6e-19 68.1 2.8 3.6e-18 66.0 2.8 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGG21383.1 - 2.5e-16 59.8 0.1 6e-16 58.6 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 EGG21383.1 - 6.9e-13 49.2 0.1 1.1e-12 48.5 0.1 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGG21383.1 - 0.00044 20.8 0.0 0.0021 18.6 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EGG21383.1 - 0.00047 20.7 0.0 0.013 16.0 0.0 2.7 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF3443 PF11925.8 EGG21383.1 - 0.0043 15.9 1.6 0.48 9.2 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3443) Ras PF00071.22 EGG21384.1 - 7.4e-35 119.9 0.0 1.6e-34 118.8 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG21384.1 - 3.7e-12 46.5 0.0 3.6e-11 43.3 0.0 2.0 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SET PF00856.28 EGG21385.1 - 1.6e-16 61.2 0.1 1.6e-16 61.2 0.1 2.7 3 1 0 3 3 3 1 SET domain TPR_8 PF13181.6 EGG21385.1 - 0.0037 17.4 1.2 1.5 9.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG21385.1 - 0.67 10.2 0.0 0.67 10.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 EGG21387.1 - 1.8e-06 27.7 4.4 1.8e-06 27.7 4.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 EGG21387.1 - 6.2e-05 23.0 19.7 0.0037 17.2 13.4 2.6 1 1 1 2 2 2 2 Seven in absentia protein family zf-TRAF PF02176.18 EGG21387.1 - 7e-05 23.4 11.4 0.0002 22.0 6.5 2.8 2 0 0 2 2 2 1 TRAF-type zinc finger zf-RING_2 PF13639.6 EGG21387.1 - 0.00011 22.5 7.1 0.00011 22.5 7.1 2.5 2 1 0 2 2 2 1 Ring finger domain MATH PF00917.26 EGG21387.1 - 0.00015 21.8 6.8 0.00015 21.8 6.8 3.9 2 2 1 3 3 3 1 MATH domain zf-RING_UBOX PF13445.6 EGG21387.1 - 0.0018 18.3 5.6 0.0018 18.3 5.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG21387.1 - 0.0027 17.5 9.0 0.0027 17.5 9.0 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG21387.1 - 0.0043 16.9 16.5 0.0098 15.7 8.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG21387.1 - 0.22 11.5 19.5 0.058 13.4 7.9 2.8 2 0 0 2 2 2 0 zinc-RING finger domain DUF2891 PF11199.8 EGG21387.1 - 0.79 8.6 7.0 0.1 11.5 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2891) zf-RING_6 PF14835.6 EGG21387.1 - 1.1 9.2 4.0 3.1 7.7 4.0 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EGG21387.1 - 3.3 7.6 12.6 0.037 13.8 4.4 2.1 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGG21387.1 - 3.7 7.8 10.7 0.37 11.0 5.5 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Actin PF00022.19 EGG21389.1 - 1.3e-88 297.4 0.0 2.2e-86 290.0 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGG21389.1 - 0.012 14.5 0.0 2.4 6.9 0.0 2.4 2 1 0 2 2 2 0 MreB/Mbl protein PH_3 PF14593.6 EGG21389.1 - 0.13 12.3 0.8 18 5.5 0.1 2.3 2 0 0 2 2 2 0 PH domain Pkinase_Tyr PF07714.17 EGG21390.1 - 4e-49 167.2 0.0 6.6e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG21390.1 - 8.9e-45 153.1 0.0 2.6e-44 151.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain F-box PF00646.33 EGG21390.1 - 2.5e-07 30.4 0.6 4.1e-06 26.5 0.1 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGG21390.1 - 2.5e-06 27.3 0.2 6.5e-06 25.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like Pkinase_fungal PF17667.1 EGG21390.1 - 0.00087 18.2 0.0 0.0023 16.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGG21390.1 - 0.001 18.5 0.0 0.0036 16.6 0.0 1.8 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGG21390.1 - 0.011 15.4 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-RING_9 PF13901.6 EGG21390.1 - 0.026 14.5 8.4 0.075 13.0 8.4 1.7 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Kdo PF06293.14 EGG21390.1 - 0.046 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHD_2 PF13831.6 EGG21390.1 - 0.068 12.7 2.4 0.14 11.7 1.0 2.2 2 0 0 2 2 2 0 PHD-finger APH PF01636.23 EGG21390.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family C1_1 PF00130.22 EGG21390.1 - 0.27 11.1 6.4 0.68 9.9 6.4 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 EGG21390.1 - 0.76 9.4 5.6 1.6 8.4 5.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 EGG21390.1 - 1.6 8.7 7.2 7.7 6.5 7.4 2.1 1 1 1 2 2 2 0 PHD-finger hDGE_amylase PF14701.6 EGG21391.1 - 8.5e-124 414.0 3.2 3.1e-122 408.9 0.9 3.1 2 1 1 3 3 3 2 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EGG21391.1 - 8.9e-110 367.2 0.0 1.4e-109 366.5 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EGG21391.1 - 1e-67 228.5 0.2 1e-67 228.5 0.2 1.7 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EGG21391.1 - 0.00012 22.1 0.2 0.00033 20.7 0.2 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme ANAPC5 PF12862.7 EGG21392.1 - 6.3e-30 103.1 0.6 1.7e-26 92.1 0.1 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 5 TPR_2 PF07719.17 EGG21392.1 - 0.00078 19.4 0.3 1.1 9.5 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG21392.1 - 0.00089 19.5 3.3 0.26 11.6 0.3 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG21392.1 - 0.00097 19.6 0.1 0.37 11.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG21392.1 - 0.0017 18.5 0.1 2.2 8.5 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG21392.1 - 0.0093 16.5 0.0 7.2 7.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG21392.1 - 0.031 14.3 0.3 56 4.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGG21392.1 - 0.051 13.8 14.2 5.4 7.5 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGG21392.1 - 0.38 10.7 2.1 3.2 7.7 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PriC PF07445.12 EGG21393.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Primosomal replication protein priC zf-C2H2 PF00096.26 EGG21396.1 - 4.7e-17 61.4 24.4 6.6e-05 23.2 0.9 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGG21396.1 - 3.7e-10 39.8 17.0 1.2e-05 25.5 2.8 5.3 6 0 0 6 6 6 3 Zinc-finger double domain LisH PF08513.11 EGG21396.1 - 4.4e-05 23.3 0.0 9.3e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 LisH zf-C2H2_4 PF13894.6 EGG21396.1 - 0.00029 21.4 2.5 0.0042 17.8 0.7 5.6 6 0 0 6 6 6 4 C2H2-type zinc finger Tetraspanin PF00335.20 EGG21396.1 - 0.00073 19.3 0.0 0.12 12.0 0.0 3.5 2 1 0 2 2 2 1 Tetraspanin family SprA-related PF12118.8 EGG21396.1 - 0.0031 16.7 9.1 0.0031 16.7 9.1 4.4 2 1 2 4 4 4 1 SprA-related family zf-C2H2_jaz PF12171.8 EGG21396.1 - 1.1 9.6 26.6 0.29 11.4 3.4 5.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Exonuc_VII_L PF02601.15 EGG21396.1 - 9.4 5.7 59.1 0.6 9.6 18.2 3.2 3 0 0 3 3 3 0 Exonuclease VII, large subunit GpcrRhopsn4 PF10192.9 EGG21397.1 - 2.5e-74 249.9 25.0 3.5e-74 249.5 25.0 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 EGG21397.1 - 0.0051 16.1 22.4 0.015 14.5 22.4 1.7 1 1 0 1 1 1 1 Lung seven transmembrane receptor MscS_TM PF12794.7 EGG21397.1 - 0.41 9.5 12.9 0.47 9.3 10.7 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 PGP_phosphatase PF09419.10 EGG21398.1 - 1.1e-37 129.2 0.0 1.3e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EGG21398.1 - 5.1e-07 29.7 0.0 7.8e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EGG21398.1 - 0.00062 19.9 0.0 0.00091 19.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG21398.1 - 0.00068 20.0 0.0 1.4 9.2 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Inhibitor_I29 PF08246.12 EGG21399.1 - 1.1e-14 54.6 1.6 3.4e-14 53.0 1.6 1.8 1 1 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF3318 PF11780.8 EGG21399.1 - 0.0032 17.4 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3318) DUF3482 PF11981.8 EGG21399.1 - 0.016 14.6 3.3 0.021 14.2 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Trp_oprn_chp PF09534.10 EGG21399.1 - 0.038 13.8 5.6 0.054 13.3 5.6 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) K-cyclin_vir_C PF09080.10 EGG21399.1 - 0.061 13.7 0.5 0.12 12.8 0.5 1.5 1 0 0 1 1 1 0 K cyclin, C terminal DUF533 PF04391.12 EGG21399.1 - 0.077 12.6 0.8 0.11 12.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Bacteriocin_IIc PF10439.9 EGG21399.1 - 0.37 10.9 12.7 0.64 10.2 12.7 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Peptidase_C1 PF00112.23 EGG21400.1 - 2.7e-52 178.0 6.7 2.7e-52 178.0 6.7 1.5 2 0 0 2 2 2 1 Papain family cysteine protease CAP PF00188.26 EGG21400.1 - 1.6e-11 45.2 3.8 3.6e-11 44.0 3.8 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RrnaAD PF00398.20 EGG21401.1 - 1.1e-48 165.6 0.0 2.9e-48 164.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGG21401.1 - 0.0006 20.5 0.4 0.0017 19.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain TFIIA PF03153.13 EGG21401.1 - 0.029 14.4 25.5 0.038 14.0 25.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3452 PF11934.8 EGG21401.1 - 0.046 13.3 0.5 0.046 13.3 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) Methyltransf_11 PF08241.12 EGG21401.1 - 0.1 13.3 0.0 0.31 11.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EGG21401.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 EGG21401.1 - 0.23 11.4 0.0 0.23 11.4 0.0 3.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGG21401.1 - 3.3 8.5 0.0 3.3 8.5 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain FAM60A PF15396.6 EGG21401.1 - 4.2 7.3 13.5 20 5.1 13.5 1.9 1 1 0 1 1 1 0 Protein Family FAM60A Peptidase_C26 PF07722.13 EGG21402.1 - 1.4e-40 139.3 0.0 5.9e-19 68.7 0.0 2.6 2 1 0 2 2 2 2 Peptidase C26 GATase PF00117.28 EGG21402.1 - 5.9e-20 71.9 0.0 5.5e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I SNO PF01174.19 EGG21402.1 - 0.0063 16.4 0.0 0.87 9.4 0.0 2.4 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Swm2 PF17083.5 EGG21402.1 - 0.077 13.0 4.0 4.9 7.2 0.8 2.5 2 0 0 2 2 2 0 Nucleolar protein Swm2 NKWYS PF10364.9 EGG21402.1 - 0.09 12.9 2.4 3.7 7.7 0.3 2.6 2 0 0 2 2 2 0 Putative capsular polysaccharide synthesis protein DASH_Duo1 PF08651.10 EGG21402.1 - 0.28 11.0 3.7 46 3.9 0.0 4.0 5 0 0 5 5 5 0 DASH complex subunit Duo1 DUF5346 PF17281.2 EGG21402.1 - 0.36 10.9 3.2 16 5.6 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5346) Far-17a_AIG1 PF04750.14 EGG21404.1 - 2.6e-27 95.5 15.4 4.8e-27 94.6 15.4 1.5 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein RMI1_N PF08585.12 EGG21405.1 - 6.3e-27 94.8 11.4 2.2e-19 70.1 0.0 3.2 1 1 2 3 3 3 2 RecQ mediated genome instability protein DUF4539 PF15072.6 EGG21405.1 - 0.0027 17.7 0.1 0.19 11.8 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) RMI1_C PF16099.5 EGG21405.1 - 0.018 14.9 0.2 0.043 13.7 0.2 1.7 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold TPP1 PF10341.9 EGG21405.1 - 0.061 13.3 0.1 0.061 13.3 0.1 3.0 3 1 0 3 3 3 0 Shelterin complex subunit, TPP1/ACD G-alpha PF00503.20 EGG21406.1 - 7.5e-96 321.4 8.2 1.8e-95 320.1 8.2 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGG21406.1 - 2.4e-12 46.6 0.0 5.9e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family MFS_1 PF07690.16 EGG21407.1 - 5.4e-23 81.5 63.7 2.2e-21 76.2 30.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Erf4 PF10256.9 EGG21407.1 - 0.031 14.4 0.0 0.9 9.7 0.0 2.8 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Trm112p PF03966.16 EGG21408.1 - 1.9e-08 34.8 0.0 3.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Trm112p-like protein FYDLN_acid PF09538.10 EGG21408.1 - 0.0016 19.1 1.7 0.0024 18.5 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) Gly-zipper_OmpA PF13436.6 EGG21409.1 - 0.024 14.4 1.7 0.024 14.4 1.7 2.4 2 0 0 2 2 2 0 Glycine-zipper domain DUF3021 PF11457.8 EGG21409.1 - 0.1 12.9 1.2 0.18 12.1 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) Tim17 PF02466.19 EGG21409.1 - 0.65 10.4 9.1 2.5 8.5 9.1 1.8 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Bromo_TP PF07524.13 EGG21410.1 - 6.4e-18 64.5 0.3 1.3e-17 63.6 0.2 1.5 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.9 EGG21410.1 - 2.9e-17 63.0 0.3 2.9e-17 63.0 0.3 2.5 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP_like PF17027.5 EGG21410.1 - 0.00065 19.8 0.6 0.0014 18.7 0.0 1.9 2 0 0 2 2 2 1 Histone-fold protein TFIID-31kDa PF02291.15 EGG21410.1 - 0.021 14.9 0.0 0.085 12.9 0.1 1.9 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit SR-25 PF10500.9 EGG21410.1 - 0.047 13.3 22.9 0.25 10.9 7.1 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 EGG21410.1 - 7 6.3 30.8 4.5 6.9 8.7 3.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein ANAPC4 PF12896.7 EGG21411.1 - 3.5e-32 111.6 11.5 3.5e-32 111.6 11.5 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EGG21411.1 - 1.4e-18 67.0 0.1 4.4e-18 65.4 0.1 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Cutinase PF01083.22 EGG21411.1 - 0.036 14.0 0.4 0.073 13.0 0.4 1.4 1 0 0 1 1 1 0 Cutinase WD40 PF00400.32 EGG21411.1 - 0.069 14.0 0.0 0.75 10.8 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat Kelch_5 PF13854.6 EGG21412.1 - 2e-10 40.4 2.5 0.29 11.2 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EGG21412.1 - 2.2e-05 24.4 0.4 0.78 9.8 0.0 5.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 EGG21412.1 - 6.8e-05 22.4 0.5 0.55 9.9 0.0 3.9 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 EGG21412.1 - 0.00016 21.8 1.0 47 4.5 0.0 5.6 5 1 1 6 6 6 0 Kelch motif Kelch_3 PF13415.6 EGG21412.1 - 0.0082 16.4 0.5 64 4.0 0.0 4.8 4 1 0 4 4 4 0 Galactose oxidase, central domain Ank_2 PF12796.7 EGG21413.1 - 3e-17 63.0 4.0 0.00026 21.5 0.3 6.7 6 1 2 8 8 8 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG21413.1 - 1.2e-12 47.8 1.7 0.046 14.1 0.1 7.7 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG21413.1 - 5.2e-10 39.7 3.6 0.11 13.1 0.2 7.7 6 2 5 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG21413.1 - 5.4e-10 38.6 6.0 19 6.2 0.0 10.6 13 0 0 13 13 13 2 Ankyrin repeat DUF249 PF03158.13 EGG21413.1 - 1.2e-05 25.1 0.3 0.2 11.4 0.0 4.0 3 0 0 3 3 3 2 Multigene family 530 protein DUF3447 PF11929.8 EGG21413.1 - 0.15 12.1 24.3 5.3 7.1 0.1 7.0 5 3 2 7 7 7 0 Domain of unknown function (DUF3447) Glyco_hydro_77 PF02446.17 EGG21415.1 - 2.1e-156 521.5 2.1 2.9e-156 521.0 2.1 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 EGG21415.1 - 3e-40 136.0 1.8 1e-19 70.2 0.2 2.7 2 0 0 2 2 2 2 Starch binding domain Imm53 PF15580.6 EGG21415.1 - 1.1 9.0 3.6 29 4.5 0.4 2.8 2 0 0 2 2 2 0 Immunity protein 53 Pro-kuma_activ PF09286.11 EGG21416.1 - 1e-29 103.7 0.1 1.7e-29 103.0 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGG21416.1 - 5.4e-06 25.9 2.6 1.2e-05 24.7 2.6 1.5 1 0 0 1 1 1 1 Subtilase family adh_short PF00106.25 EGG21417.1 - 1.4e-16 60.5 0.0 6.7e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG21417.1 - 1.5e-11 44.4 0.0 2.6e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG21419.1 - 8.3e-15 54.8 0.0 1.5e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG21419.1 - 4.5e-10 39.5 0.0 0.00031 20.4 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Ank_2 PF12796.7 EGG21420.1 - 2.3e-22 79.4 5.5 8.4e-09 35.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG21420.1 - 3.8e-19 68.5 0.9 2.2e-09 37.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG21420.1 - 6.2e-18 64.9 1.1 1.3e-05 25.7 0.1 5.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EGG21420.1 - 4.9e-17 61.5 4.9 0.0002 21.6 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EGG21420.1 - 8.3e-16 56.5 2.7 0.0016 18.8 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat GRAM PF02893.20 EGG21420.1 - 0.05 13.5 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 GRAM domain GAS2 PF02187.17 EGG21422.1 - 3e-05 24.0 0.0 9.7e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain PH_8 PF15409.6 EGG21422.1 - 0.019 15.2 0.1 0.099 12.9 0.1 2.2 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 EGG21422.1 - 2 8.9 10.9 0.36 11.3 0.4 4.3 4 1 0 4 4 4 0 Pleckstrin homology domain AMP-binding PF00501.28 EGG21423.1 - 3.1e-88 296.2 10.0 5.1e-88 295.5 1.5 3.3 2 1 0 2 2 2 2 AMP-binding enzyme PIF1 PF05970.14 EGG21425.1 - 1.1e-50 172.8 3.1 2e-40 139.1 0.2 5.1 4 1 0 4 4 4 2 PIF1-like helicase AAA_30 PF13604.6 EGG21425.1 - 5.8e-21 75.1 0.0 4.7e-19 68.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGG21425.1 - 2.4e-11 44.2 3.2 3.3e-11 43.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EGG21425.1 - 0.00041 20.1 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 EGG21425.1 - 0.0021 18.3 0.1 0.011 16.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG21425.1 - 0.013 15.9 0.0 0.044 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 EGG21425.1 - 0.048 13.0 0.8 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Dickkopf_N PF04706.12 EGG21425.1 - 1.2 9.7 72.7 2.8 8.5 10.6 6.0 5 1 0 5 5 5 0 Dickkopf N-terminal cysteine-rich region p450 PF00067.22 EGG21426.1 - 6.2e-180 598.9 0.0 5.1e-94 315.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF1374 PF07118.11 EGG21426.1 - 0.061 13.8 0.1 0.42 11.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) DUF3687 PF12459.8 EGG21426.1 - 8.6 6.0 7.9 26 4.4 1.2 2.7 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein V-SNARE_C PF12352.8 EGG21427.1 - 2.6e-07 30.8 3.3 2.6e-07 30.8 3.3 3.1 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 EGG21427.1 - 0.00011 22.4 4.3 0.00011 22.4 4.3 3.0 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus FliJ PF02050.16 EGG21427.1 - 0.00066 19.9 10.0 0.15 12.3 3.5 2.3 1 1 0 2 2 2 2 Flagellar FliJ protein NPV_P10 PF05531.12 EGG21427.1 - 0.0016 18.8 8.0 0.019 15.4 0.3 3.3 2 2 1 3 3 3 1 Nucleopolyhedrovirus P10 protein DASH_Duo1 PF08651.10 EGG21427.1 - 0.0021 17.8 9.3 1.8 8.4 0.4 4.5 3 2 0 4 4 4 1 DASH complex subunit Duo1 Cas_DxTHG PF09455.10 EGG21427.1 - 0.0044 16.7 7.1 0.0062 16.2 7.1 1.1 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family DUF5357 PF17310.2 EGG21427.1 - 0.006 15.2 2.4 0.0065 15.1 1.7 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF5357) Tropomyosin PF00261.20 EGG21427.1 - 0.0068 15.8 10.8 0.38 10.1 2.0 2.1 1 1 0 1 1 1 1 Tropomyosin EzrA PF06160.12 EGG21427.1 - 0.014 13.7 14.0 0.16 10.1 1.2 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Sec20 PF03908.13 EGG21427.1 - 0.019 14.9 2.7 0.019 14.9 2.7 3.1 1 1 2 3 3 3 0 Sec20 PilJ PF13675.6 EGG21427.1 - 0.034 14.1 1.9 0.67 10.0 0.2 2.8 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Exonuc_VII_S PF02609.16 EGG21427.1 - 0.07 13.2 1.3 0.33 11.0 0.1 2.7 2 0 0 2 2 2 0 Exonuclease VII small subunit Tropomyosin_1 PF12718.7 EGG21427.1 - 0.092 12.9 11.2 1.9 8.6 1.5 2.2 1 1 1 2 2 2 0 Tropomyosin like MCPsignal PF00015.21 EGG21427.1 - 0.098 12.5 7.0 0.37 10.6 1.2 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF16 PF01519.16 EGG21427.1 - 0.11 13.0 17.4 1.9 9.0 3.8 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF745 PF05335.13 EGG21427.1 - 0.12 12.1 9.9 0.34 10.6 2.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Med9 PF07544.13 EGG21427.1 - 0.13 12.3 10.2 0.15 12.2 1.1 3.2 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 MscS_porin PF12795.7 EGG21427.1 - 0.13 11.8 9.9 2 7.9 3.1 2.7 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain RmuC PF02646.16 EGG21427.1 - 0.14 11.2 10.7 0.53 9.4 1.2 2.7 1 1 2 3 3 3 0 RmuC family Exonuc_VII_L PF02601.15 EGG21427.1 - 0.18 11.4 12.1 1 8.9 12.1 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit DivIVA PF05103.13 EGG21427.1 - 0.21 11.7 9.5 0.51 10.4 4.5 2.8 1 1 2 3 3 3 0 DivIVA protein CENP-H PF05837.12 EGG21427.1 - 0.22 11.9 12.5 0.51 10.8 2.6 2.6 1 1 2 3 3 3 0 Centromere protein H (CENP-H) DUF713 PF05218.14 EGG21427.1 - 0.28 10.9 9.1 2.2 8.0 9.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF713) DUF1664 PF07889.12 EGG21427.1 - 0.28 11.2 14.1 0.96 9.5 4.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) COG5 PF10392.9 EGG21427.1 - 0.38 10.9 8.5 0.26 11.4 2.2 2.7 1 1 1 2 2 2 0 Golgi transport complex subunit 5 LMBR1 PF04791.16 EGG21427.1 - 0.41 9.5 7.1 0.46 9.3 7.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Syntaxin-6_N PF09177.11 EGG21427.1 - 0.43 11.2 8.4 32 5.2 8.4 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 EGG21427.1 - 0.46 10.9 17.0 2.8 8.4 1.4 4.4 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) AATF-Che1 PF13339.6 EGG21427.1 - 0.84 10.3 12.7 42 4.8 12.2 2.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor KELK PF15796.5 EGG21427.1 - 0.92 10.0 8.9 0.52 10.8 0.3 2.9 1 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TcdB_N PF12918.7 EGG21427.1 - 1 9.7 7.9 4.6 7.6 1.7 3.4 1 1 2 3 3 3 0 TcdB toxin N-terminal helical domain Phage_GPO PF05929.11 EGG21427.1 - 1 8.9 9.4 3 7.4 1.2 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase THOC7 PF05615.13 EGG21427.1 - 1.1 9.5 12.9 0.21 11.9 2.2 2.9 1 1 1 2 2 2 0 Tho complex subunit 7 Snapin_Pallidin PF14712.6 EGG21427.1 - 1.2 9.6 16.0 2.3 8.7 4.0 3.6 1 1 2 3 3 3 0 Snapin/Pallidin Nup88 PF10168.9 EGG21427.1 - 1.3 6.8 14.2 0.37 8.5 10.4 1.8 1 1 1 2 2 2 0 Nuclear pore component TMPIT PF07851.13 EGG21427.1 - 1.3 8.2 14.2 1.4 8.1 9.2 2.3 1 1 2 3 3 3 0 TMPIT-like protein KLRAQ PF10205.9 EGG21427.1 - 1.6 9.0 12.2 0.046 14.0 2.1 2.9 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein WXG100 PF06013.12 EGG21427.1 - 1.6 9.0 8.4 19 5.6 0.2 3.9 2 1 0 3 3 3 0 Proteins of 100 residues with WXG YlqD PF11068.8 EGG21427.1 - 1.7 9.0 14.7 28 5.1 9.3 3.0 1 1 1 2 2 2 0 YlqD protein GCN5L1 PF06320.13 EGG21427.1 - 1.8 8.7 7.9 2.5 8.3 0.6 2.5 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Atg14 PF10186.9 EGG21427.1 - 1.9 7.5 12.7 11 5.0 10.2 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CorA PF01544.18 EGG21427.1 - 2 7.7 8.1 2.8 7.2 5.5 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 EGG21427.1 - 2 8.7 8.3 25 5.2 1.5 3.7 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) ALMT PF11744.8 EGG21427.1 - 2 7.1 9.0 2.5 6.8 9.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Prominin PF05478.11 EGG21427.1 - 2.4 6.0 11.1 3.1 5.7 11.1 1.2 1 0 0 1 1 1 0 Prominin DHR10 PF18595.1 EGG21427.1 - 2.6 8.2 13.8 4.2 7.5 2.1 3.3 2 2 1 3 3 3 0 Designed helical repeat protein 10 domain DUF4363 PF14276.6 EGG21427.1 - 3 8.0 11.2 9 6.5 3.3 3.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4363) HLH PF00010.26 EGG21427.1 - 3.2 7.8 7.0 0.47 10.5 0.5 2.8 3 1 0 3 3 2 0 Helix-loop-helix DNA-binding domain Laminin_II PF06009.12 EGG21427.1 - 3.6 7.6 11.9 1.5 8.8 6.3 2.6 1 1 1 2 2 2 0 Laminin Domain II XhlA PF10779.9 EGG21427.1 - 3.9 7.8 17.0 1.5 9.1 1.5 4.1 2 2 2 4 4 4 0 Haemolysin XhlA SOAR PF16533.5 EGG21427.1 - 4 7.5 7.7 14 5.7 2.3 3.3 1 1 3 4 4 3 0 STIM1 Orai1-activating region Prefoldin_2 PF01920.20 EGG21427.1 - 4.1 7.4 15.2 3.7 7.6 3.8 3.8 2 2 0 3 3 3 0 Prefoldin subunit PCRF PF03462.18 EGG21427.1 - 4.5 7.1 11.2 2.5 8.0 3.0 2.2 1 1 1 2 2 2 0 PCRF domain bZIP_1 PF00170.21 EGG21427.1 - 5.1 7.3 12.4 0.2 11.8 1.1 3.4 3 1 1 4 4 3 0 bZIP transcription factor L31 PF09784.9 EGG21427.1 - 6.1 7.3 7.9 21 5.6 0.1 3.5 1 1 2 3 3 3 0 Mitochondrial ribosomal protein L31 Bul1_C PF04426.12 EGG21427.1 - 6.8 6.0 15.8 4.1 6.7 11.0 2.0 1 1 1 2 2 2 0 Bul1 C terminus APG6_N PF17675.1 EGG21427.1 - 7.3 7.1 12.1 8.4 6.9 3.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Mis14 PF08641.12 EGG21427.1 - 8.4 6.7 13.6 4.9 7.5 3.1 3.2 1 1 2 3 3 3 0 Kinetochore protein Mis14 like 4HBT PF03061.22 EGG21428.1 - 0.0033 17.7 0.0 0.0049 17.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily CUE PF02845.16 EGG21429.1 - 4.3e-08 32.7 0.0 1.2e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 CUE domain ZapA PF05164.13 EGG21429.1 - 9.6 6.7 12.9 4.9 7.6 0.5 3.9 3 1 0 3 3 3 0 Cell division protein ZapA DNApol3-delta_C PF09115.10 EGG21430.1 - 0.031 14.8 1.4 0.37 11.3 0.0 3.4 4 0 0 4 4 4 0 DNA polymerase III, delta subunit, C terminal Radial_spoke PF04712.12 EGG21430.1 - 6 5.7 7.8 0.94 8.3 1.6 2.0 2 0 0 2 2 2 0 Radial spokehead-like protein UQ_con PF00179.26 EGG21431.1 - 3.5e-29 101.3 0.1 3.9e-29 101.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGG21431.1 - 0.0018 18.0 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGG21431.1 - 0.06 13.6 0.2 0.089 13.1 0.2 1.4 1 1 0 1 1 1 0 RWD domain Nucleotid_trans PF03407.16 EGG21432.1 - 3.2e-29 102.4 0.0 6.7e-27 94.9 0.0 2.3 2 0 0 2 2 2 2 Nucleotide-diphospho-sugar transferase WD40 PF00400.32 EGG21432.1 - 3.3e-26 91.0 22.7 1e-05 26.2 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 EGG21432.1 - 7e-07 28.3 2.9 0.0055 15.4 0.0 3.6 2 2 2 4 4 4 3 Nucleoporin Nup120/160 zf-B_box PF00643.24 EGG21432.1 - 0.00021 21.4 10.6 0.00045 20.3 10.6 1.5 1 0 0 1 1 1 1 B-box zinc finger PALB2_WD40 PF16756.5 EGG21432.1 - 0.027 13.4 0.4 6.9 5.5 0.0 2.4 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain BBS2_Mid PF14783.6 EGG21432.1 - 0.029 14.4 0.1 3.4 7.7 0.0 3.2 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 EGG21432.1 - 0.049 14.1 0.0 17 6.1 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain zf-piccolo PF05715.13 EGG21432.1 - 0.12 12.5 6.6 0.28 11.3 6.6 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger DUF2076 PF09849.9 EGG21433.1 - 0.56 10.2 11.9 1.2 9.1 11.9 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ELMO_CED12 PF04727.13 EGG21434.1 - 1.5e-43 148.9 1.3 3.5e-43 147.8 1.3 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family FSA_C PF10479.9 EGG21434.1 - 8.9 4.3 15.7 0.91 7.6 10.8 1.7 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus Orf78 PF06024.12 EGG21435.1 - 5.6 7.3 11.0 8.2 6.8 0.0 2.8 3 0 0 3 3 3 0 Orf78 (ac78) Peptidase_C78 PF07910.13 EGG21436.1 - 2.7e-53 180.6 0.1 2.7e-53 180.6 0.1 2.1 2 1 0 2 2 2 1 Peptidase family C78 CRC_subunit PF08624.10 EGG21436.1 - 0.26 11.7 2.1 0.51 10.8 1.3 1.9 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit Peptidase_S24 PF00717.23 EGG21437.1 - 4.6e-08 32.9 0.7 1.3e-07 31.5 0.7 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EGG21437.1 - 4.8e-07 29.7 0.0 9.1e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 SR-25 PF10500.9 EGG21437.1 - 0.00064 19.4 1.8 0.00095 18.8 1.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Orf78 PF06024.12 EGG21437.1 - 0.028 14.7 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Viral_helicase1 PF01443.18 EGG21437.1 - 0.063 13.0 1.2 2.4 7.8 1.1 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF3682 PF12446.8 EGG21437.1 - 0.54 10.7 7.1 0.78 10.2 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) SprA-related PF12118.8 EGG21437.1 - 1.7 7.7 8.4 2.5 7.2 8.4 1.1 1 0 0 1 1 1 0 SprA-related family NifU_N PF01592.16 EGG21438.1 - 2.2e-52 176.6 0.1 2.2e-52 176.6 0.1 1.4 2 0 0 2 2 2 1 NifU-like N terminal domain SR-25 PF10500.9 EGG21438.1 - 2.9 7.4 8.4 4.6 6.8 8.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Snapin_Pallidin PF14712.6 EGG21439.1 - 4.8e-22 78.2 0.6 4.8e-22 78.2 0.6 2.4 3 0 0 3 3 2 1 Snapin/Pallidin DUF489 PF04356.12 EGG21439.1 - 0.00088 19.3 1.3 0.0017 18.4 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF489) DUF4820 PF16091.5 EGG21439.1 - 0.014 14.7 10.6 0.023 14.1 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3526 PF12040.8 EGG21439.1 - 0.015 15.8 1.1 3.2 8.2 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3526) GCN5L1 PF06320.13 EGG21439.1 - 0.046 13.9 0.3 0.046 13.9 0.3 3.1 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) VPS11_C PF12451.8 EGG21439.1 - 0.15 12.3 0.5 0.15 12.3 0.5 2.2 3 0 0 3 3 2 0 Vacuolar protein sorting protein 11 C terminal TFIIA PF03153.13 EGG21439.1 - 1 9.3 20.4 1.1 9.2 20.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3772 PF12607.8 EGG21439.1 - 1.2 9.0 6.9 19 5.1 3.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) XRN_M PF17846.1 EGG21439.1 - 1.6 7.6 12.8 1.7 7.5 12.0 1.3 1 1 0 1 1 1 0 Xrn1 helical domain DUF572 PF04502.13 EGG21439.1 - 3.2 7.3 21.3 4.2 6.9 21.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Serinc PF03348.15 EGG21439.1 - 6.1 5.7 6.1 7.8 5.3 6.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) YabA PF06156.13 EGG21439.1 - 8.9 7.0 19.6 1 10.0 4.9 2.6 2 1 0 2 2 2 0 Initiation control protein YabA Sulfate_transp PF00916.20 EGG21441.1 - 2.9e-99 332.4 21.3 4.4e-99 331.8 21.3 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGG21441.1 - 1.2e-17 63.6 0.1 2.1e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGG21441.1 - 0.017 15.5 2.2 0.017 15.5 2.2 2.9 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily AAA_16 PF13191.6 EGG21442.1 - 8.7e-07 29.5 0.0 1.7e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG21442.1 - 0.00028 21.1 0.0 0.00081 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain VATC PF18716.1 EGG21442.1 - 0.0083 16.0 0.5 0.021 14.7 0.5 1.6 1 0 0 1 1 1 1 Vms1-associating treble clef domain AAA_PrkA PF08298.11 EGG21442.1 - 0.055 12.4 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain NACHT PF05729.12 EGG21442.1 - 0.079 12.9 0.0 0.38 10.7 0.0 2.1 2 1 0 2 2 2 0 NACHT domain MIP PF00230.20 EGG21443.1 - 2.3e-48 164.9 11.8 2.8e-48 164.6 11.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein A_deaminase PF00962.22 EGG21444.1 - 4.7e-119 397.6 0.1 6.2e-119 397.2 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF3498 PF12004.8 EGG21445.1 - 0.4 9.8 10.6 0.63 9.2 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Pkinase PF00069.25 EGG21446.1 - 8.6e-81 271.2 0.0 1.1e-80 270.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21446.1 - 2.1e-42 145.2 0.0 3.5e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGG21446.1 - 3.7e-05 23.2 0.0 7e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Homeodomain PF00046.29 EGG21447.1 - 4.1e-15 55.4 4.6 4.1e-15 55.4 4.6 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 EGG21447.1 - 3.7e-06 26.7 0.1 3.7e-06 26.7 0.1 2.5 3 0 0 3 3 3 1 Homeobox KN domain CALM_bind PF16025.5 EGG21447.1 - 0.061 13.8 0.6 0.061 13.8 0.6 3.1 2 1 0 2 2 2 0 Calcium-dependent calmodulin binding Androgen_recep PF02166.16 EGG21447.1 - 1.1 8.0 24.3 0.41 9.4 0.1 2.5 2 0 0 2 2 2 0 Androgen receptor CDC27 PF09507.10 EGG21447.1 - 6.4 6.0 34.4 0.75 9.1 12.4 2.3 1 1 1 2 2 2 0 DNA polymerase subunit Cdc27 PolyA_pol PF01743.20 EGG21450.1 - 1.9e-19 70.3 0.0 4.3e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EGG21450.1 - 9.2e-07 28.5 0.0 3.5e-06 26.7 0.0 2.0 1 1 1 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A DUF885 PF05960.11 EGG21451.1 - 2e-126 423.7 0.2 2.6e-125 420.1 0.0 2.6 4 0 0 4 4 4 1 Bacterial protein of unknown function (DUF885) Vps52 PF04129.12 EGG21451.1 - 6.2e-49 167.1 25.4 8.6e-43 146.8 24.5 2.9 2 1 0 2 2 2 2 Vps52 / Sac2 family Tox-GHH PF15636.6 EGG21451.1 - 0.063 13.3 0.2 12 5.9 0.0 2.8 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin BSD PF03909.17 EGG21451.1 - 0.1 12.6 0.2 0.1 12.6 0.2 3.5 4 0 0 4 4 4 0 BSD domain DUF4064 PF13273.6 EGG21452.1 - 0.056 13.7 3.2 0.09 13.1 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) GTP_EFTU PF00009.27 EGG21453.1 - 7.2e-44 149.7 0.1 1.6e-43 148.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGG21453.1 - 8.8e-26 90.4 0.0 2.5e-25 89.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGG21453.1 - 6.9e-05 23.2 0.8 6.9e-05 23.2 0.8 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGG21453.1 - 0.00022 21.3 0.1 0.0062 16.6 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EGG21453.1 - 0.0012 18.7 1.5 0.0028 17.5 1.5 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 DUF1296 PF06972.11 EGG21453.1 - 0.0019 18.3 0.4 0.0057 16.8 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) HBS1_N PF08938.10 EGG21453.1 - 0.042 14.2 0.9 0.094 13.0 0.9 1.6 1 0 0 1 1 1 0 HBS1 N-terminus JIP_LZII PF16471.5 EGG21453.1 - 0.053 13.7 0.2 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II HGTP_anticodon2 PF12745.7 EGG21453.1 - 2.2 7.7 6.6 1.2 8.6 0.4 2.1 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs DUF3430 PF11912.8 EGG21454.1 - 5e-07 30.0 14.9 7.7e-05 22.8 4.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGG21454.1 - 0.065 13.5 4.8 0.37 11.0 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) ArfGap PF01412.18 EGG21455.1 - 1.5e-27 96.0 0.0 1.5e-27 96.0 0.0 4.4 4 2 2 6 6 6 1 Putative GTPase activating protein for Arf zf-B_box PF00643.24 EGG21455.1 - 0.0022 18.1 0.3 0.0022 18.1 0.3 1.6 2 0 0 2 2 2 1 B-box zinc finger FAM220 PF15487.6 EGG21458.1 - 0.051 13.2 2.3 0.073 12.7 1.4 1.6 2 0 0 2 2 2 0 FAM220 family Gemini_mov PF01708.16 EGG21458.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Geminivirus putative movement protein DUF4446 PF14584.6 EGG21459.1 - 0.066 13.2 0.0 0.066 13.2 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4446) Dynein_IC2 PF11540.8 EGG21460.1 - 1.3e-12 47.4 3.0 5.1e-12 45.5 3.0 2.1 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.32 EGG21460.1 - 2.1e-09 37.8 20.3 0.042 14.7 1.4 7.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG21460.1 - 0.0021 18.3 0.0 0.075 13.3 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SUKH_6 PF14568.6 EGG21460.1 - 0.23 11.9 2.1 19 5.7 0.0 3.7 4 0 0 4 4 4 0 SMI1-KNR4 cell-wall Hira PF07569.11 EGG21460.1 - 1.1 9.0 8.1 0.62 9.8 0.7 3.2 3 1 1 4 4 4 0 TUP1-like enhancer of split MCM PF00493.23 EGG21461.1 - 8.1e-103 342.3 1.2 4.2e-102 340.0 0.0 2.1 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EGG21461.1 - 4e-36 123.7 0.6 7.3e-36 122.8 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGG21461.1 - 5.2e-27 94.1 0.3 1.1e-26 93.0 0.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGG21461.1 - 1.7e-17 63.9 2.4 2.7e-17 63.3 1.1 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGG21461.1 - 4.9e-06 26.1 0.0 0.0022 17.4 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGG21461.1 - 5.4e-05 23.2 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGG21461.1 - 0.0017 18.2 0.0 0.0047 16.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGG21461.1 - 0.028 14.1 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Fanconi_A_N PF15865.5 EGG21461.1 - 0.039 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus Methyltransf_16 PF10294.9 EGG21462.1 - 1.2e-14 54.4 0.0 1.9e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGG21462.1 - 2e-08 34.3 0.0 3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG21462.1 - 0.00015 22.3 0.0 0.00042 20.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG21462.1 - 0.00019 21.3 0.1 0.00074 19.3 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG21462.1 - 0.0011 19.6 0.0 0.009 16.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG21462.1 - 0.0014 19.3 0.0 0.0039 17.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EGG21462.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MTS PF05175.14 EGG21462.1 - 0.03 13.9 0.0 0.92 9.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Sec6 PF06046.13 EGG21463.1 - 1.2e-120 403.7 10.6 1.5e-120 403.3 10.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF3629 PF12302.8 EGG21463.1 - 0.098 12.1 0.3 0.27 10.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) FlgN PF05130.12 EGG21463.1 - 0.15 12.6 7.5 0.31 11.5 0.2 3.2 3 0 0 3 3 3 0 FlgN protein ketoacyl-synt PF00109.26 EGG21465.1 - 4.2e-49 167.4 0.1 6.8e-49 166.7 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EGG21465.1 - 4e-41 140.7 0.2 7.1e-41 139.9 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGG21465.1 - 3.6e-39 133.9 0.0 8.2e-39 132.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGG21465.1 - 2.1e-31 108.4 0.3 4.7e-31 107.3 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGG21465.1 - 8.9e-28 96.3 0.1 2.6e-27 94.9 0.1 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGG21465.1 - 1.8e-12 47.7 0.0 3.2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Thiolase_N PF00108.23 EGG21465.1 - 0.00028 20.3 0.0 0.00096 18.6 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain HpaB_N PF11794.8 EGG21465.1 - 0.043 13.5 0.0 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal 6PGD PF00393.19 EGG21466.1 - 9e-129 428.9 0.0 9e-129 428.9 0.0 1.9 2 0 0 2 2 2 1 6-phosphogluconate dehydrogenase, C-terminal domain SIR2 PF02146.17 EGG21466.1 - 1.9e-56 190.8 0.0 4.5e-56 189.6 0.0 1.7 1 0 0 1 1 1 1 Sir2 family NAD_binding_2 PF03446.15 EGG21466.1 - 3.5e-51 173.5 0.1 3.5e-51 173.5 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase zf-UBP PF02148.19 EGG21466.1 - 1.7e-16 60.3 9.9 1.7e-16 60.3 9.9 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Shikimate_DH PF01488.20 EGG21466.1 - 0.0031 17.6 0.0 0.011 15.8 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Mucin PF01456.17 EGG21466.1 - 0.036 14.1 18.8 0.063 13.3 18.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein NAD_binding_11 PF14833.6 EGG21466.1 - 0.078 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Dicty_REP PF05086.12 EGG21466.1 - 0.32 8.9 9.1 0.52 8.2 9.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zinc_ribbon_9 PF14369.6 EGG21466.1 - 0.35 11.2 4.2 0.19 12.0 0.6 2.6 2 0 0 2 2 2 0 zinc-ribbon DUF3973 PF13119.6 EGG21466.1 - 0.59 10.3 3.2 1.7 8.8 3.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) NST1 PF13945.6 EGG21466.1 - 0.91 9.6 6.5 1.5 8.9 6.5 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator CC190 PF15768.5 EGG21466.1 - 1.7 8.6 5.3 2.8 8.0 5.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Pex19 PF04614.12 EGG21466.1 - 3.7 7.2 8.0 6 6.6 8.0 1.2 1 0 0 1 1 1 0 Pex19 protein family CRAL_TRIO PF00650.20 EGG21467.1 - 1.3e-23 83.4 0.3 1.9e-23 83.0 0.3 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGG21467.1 - 1.3e-06 28.6 0.1 3.2e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Pkinase PF00069.25 EGG21468.1 - 8.9e-76 254.7 0.2 1.2e-75 254.4 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21468.1 - 1.1e-40 139.6 0.0 1.5e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EGG21468.1 - 1.8e-07 31.6 0.1 1.3e-06 28.9 0.1 2.3 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 EGG21468.1 - 3.4e-06 26.6 0.0 5.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 EGG21468.1 - 1.9e-05 24.3 0.9 0.00011 21.9 0.0 2.5 2 0 0 2 2 2 1 Kinase associated domain 1 APH PF01636.23 EGG21468.1 - 0.044 13.7 0.1 1.3 8.9 0.3 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family UBA_3 PF09288.10 EGG21468.1 - 7.3 6.5 6.4 24 4.8 0.0 2.8 3 0 0 3 3 3 0 Fungal ubiquitin-associated domain EphA2_TM PF14575.6 EGG21469.1 - 0.00011 23.0 0.1 0.21 12.5 0.0 2.1 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain ATP-synt_8 PF00895.20 EGG21469.1 - 0.00043 20.7 1.6 0.057 13.9 0.1 2.4 2 0 0 2 2 2 1 ATP synthase protein 8 Mid2 PF04478.12 EGG21469.1 - 0.0015 18.4 1.5 0.0023 17.8 1.2 1.5 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor DUF3827 PF12877.7 EGG21469.1 - 0.0019 16.7 0.0 0.0024 16.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) Baculo_11_kDa PF06143.11 EGG21469.1 - 0.0025 17.4 0.8 0.18 11.4 0.8 2.3 2 0 0 2 2 2 1 Baculovirus 11 kDa family Ac76 PF05814.11 EGG21469.1 - 0.0043 17.0 1.6 0.42 10.7 0.9 2.3 2 0 0 2 2 2 1 Orf76 (Ac76) RSN1_TM PF13967.6 EGG21469.1 - 0.0054 16.5 0.9 0.0094 15.7 0.9 1.3 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport Cadherin_C_2 PF16492.5 EGG21469.1 - 0.0082 16.9 0.2 0.065 14.0 0.1 2.0 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal 7TM_GPCR_Srd PF10317.9 EGG21469.1 - 0.01 15.0 0.6 0.013 14.8 0.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd LRRC37AB_C PF14914.6 EGG21469.1 - 0.014 15.3 0.1 0.014 15.3 0.1 2.1 1 1 2 3 3 3 0 LRRC37A/B like protein 1 C-terminal domain TMEM51 PF15345.6 EGG21469.1 - 0.015 15.2 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 SCIMP PF15050.6 EGG21469.1 - 0.016 15.7 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 SCIMP protein DUF5083 PF16890.5 EGG21469.1 - 0.018 14.8 0.1 0.024 14.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) DUF2615 PF11027.8 EGG21469.1 - 0.021 14.9 1.5 0.44 10.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Orf78 PF06024.12 EGG21469.1 - 0.022 15.0 0.3 0.022 15.0 0.3 2.1 1 1 1 2 2 2 0 Orf78 (ac78) DUF898 PF05987.13 EGG21469.1 - 0.023 13.8 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DHHC PF01529.20 EGG21469.1 - 0.026 14.6 0.2 0.035 14.2 0.2 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF4969 PF16339.5 EGG21469.1 - 0.027 14.8 0.7 9.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) Pilin_N PF07790.11 EGG21469.1 - 0.038 14.9 0.0 0.19 12.7 0.0 2.0 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal DUF5385 PF17359.2 EGG21469.1 - 0.048 13.2 0.1 0.31 10.6 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5385) S1FA PF04689.13 EGG21469.1 - 0.049 13.8 0.1 0.086 13.0 0.1 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA DUF4834 PF16118.5 EGG21469.1 - 0.054 14.5 0.1 3.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) OSTbeta PF15048.6 EGG21469.1 - 0.055 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Syndecan PF01034.20 EGG21469.1 - 0.062 13.2 0.1 0.062 13.2 0.1 1.9 2 0 0 2 2 2 0 Syndecan domain TMEM132D_C PF15706.5 EGG21469.1 - 0.067 13.0 0.4 0.11 12.2 0.1 1.6 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4436 PF14494.6 EGG21469.1 - 0.088 12.1 0.1 0.14 11.4 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4436) Shisa PF13908.6 EGG21469.1 - 0.089 13.0 0.2 0.13 12.5 0.2 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3671 PF12420.8 EGG21469.1 - 0.094 12.8 1.7 0.21 11.7 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function TMEM154 PF15102.6 EGG21469.1 - 0.11 12.4 4.5 0.063 13.2 1.8 1.9 1 1 1 2 2 2 0 TMEM154 protein family Sigma_reg_N PF13800.6 EGG21469.1 - 0.33 11.3 4.7 0.71 10.2 0.4 2.5 3 0 0 3 3 2 0 Sigma factor regulator N-terminal Gemini_mov PF01708.16 EGG21469.1 - 0.57 10.0 2.6 1 9.2 2.3 1.6 1 1 0 1 1 1 0 Geminivirus putative movement protein EMP70 PF02990.16 EGG21469.1 - 0.59 8.7 4.9 0.51 8.9 0.6 1.9 1 1 1 2 2 2 0 Endomembrane protein 70 Endomucin PF07010.12 EGG21469.1 - 1.1 9.2 7.9 1.5 8.7 7.9 1.5 1 1 0 1 1 1 0 Endomucin ECSCR PF15820.5 EGG21469.1 - 3.9 7.4 8.9 1.3 8.9 5.0 2.0 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator ODV-E18 PF10717.9 EGG21469.1 - 4.6 7.2 19.8 0.59 10.0 1.9 2.7 1 1 2 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 LRR19-TM PF15176.6 EGG21469.1 - 5 7.2 7.5 4.2 7.4 4.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF5383 PF17355.2 EGG21469.1 - 9 6.7 6.5 2 8.8 0.7 2.6 1 1 2 3 3 3 0 Family of unknown function (DUF5383) Pkinase PF00069.25 EGG21470.1 - 2.6e-51 174.5 1.4 6.3e-51 173.3 1.4 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21470.1 - 8.5e-22 77.7 0.3 7.4e-21 74.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EGG21470.1 - 0.0032 16.5 1.2 0.0054 15.8 1.2 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase DDE_Tnp_1_7 PF13843.6 EGG21471.1 - 1.4e-27 96.9 0.1 1.4e-27 96.9 0.1 3.3 3 0 0 3 3 3 2 Transposase IS4 BSP_II PF05432.11 EGG21471.1 - 0.00046 20.0 29.9 0.017 14.8 14.6 2.6 2 0 0 2 2 2 2 Bone sialoprotein II (BSP-II) DUF2052 PF09747.9 EGG21471.1 - 1.9 8.6 31.9 0.26 11.4 7.2 3.4 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Tim54 PF11711.8 EGG21471.1 - 5.7 5.6 21.1 0.089 11.6 1.3 3.1 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 EAP30 PF04157.16 EGG21472.1 - 2.8e-70 236.3 0.2 3.3e-70 236.1 0.2 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family YfdX PF10938.8 EGG21472.1 - 0.062 13.2 0.2 6.4 6.7 0.1 2.1 2 0 0 2 2 2 0 YfdX protein PRP9_N PF16958.5 EGG21472.1 - 0.066 13.2 4.2 0.13 12.3 4.2 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus DUF1319 PF07028.11 EGG21473.1 - 0.00095 19.4 0.1 0.0011 19.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1319) SapC PF07277.11 EGG21473.1 - 0.048 13.2 0.0 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 SapC PriA_3primeBD PF17764.1 EGG21473.1 - 0.068 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) M PF02370.16 EGG21473.1 - 2.2 9.1 7.4 3.6 8.5 7.4 1.4 1 0 0 1 1 1 0 M protein repeat GTP_EFTU PF00009.27 EGG21474.1 - 3.9e-53 179.9 0.9 3.9e-53 179.9 0.9 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGG21474.1 - 1.6e-17 63.3 0.0 4e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 EGG21474.1 - 3.2e-06 27.2 0.3 1e-05 25.6 0.3 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EGG21474.1 - 0.00049 19.5 0.2 0.00098 18.5 0.2 1.4 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 EGG21474.1 - 0.0048 17.0 0.7 0.018 15.1 0.7 2.1 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 EGG21474.1 - 0.0075 15.8 0.5 0.048 13.2 0.5 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 EGG21474.1 - 0.0098 15.3 0.1 0.0098 15.3 0.1 2.7 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGG21474.1 - 0.025 14.8 1.6 0.028 14.7 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CitMHS PF03600.16 EGG21475.1 - 1.8e-40 139.0 12.4 2.3e-40 138.7 12.4 1.1 1 0 0 1 1 1 1 Citrate transporter ArsB PF02040.15 EGG21475.1 - 8.7e-07 28.6 9.8 8.7e-07 28.6 9.8 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein RhoGAP PF00620.27 EGG21476.1 - 2.6e-31 108.5 0.0 2.6e-31 108.5 0.0 3.0 4 0 0 4 4 4 1 RhoGAP domain PBD PF00786.28 EGG21476.1 - 0.016 15.6 0.2 0.14 12.5 0.1 2.6 2 0 0 2 2 2 0 P21-Rho-binding domain GlcNAc PF11397.8 EGG21477.1 - 4.5e-80 269.7 0.4 7.7e-64 216.3 0.4 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) eRF1_2 PF03464.15 EGG21478.1 - 5.5e-41 140.0 0.4 1.1e-23 84.0 0.1 2.3 1 1 1 2 2 2 2 eRF1 domain 2 eRF1_3 PF03465.15 EGG21478.1 - 1.4e-37 128.6 0.3 3.8e-37 127.2 0.1 1.9 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 EGG21478.1 - 2.2e-20 73.0 0.0 3.7e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 EGG21478.1 - 3.2e-07 30.7 0.4 6.3e-07 29.7 0.4 1.5 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 EGG21478.1 - 1.2e-06 28.8 0.1 5.2e-06 26.7 0.3 1.9 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 Nsp1_C PF05064.13 EGG21479.1 - 4.6e-15 55.4 12.7 4.6e-15 55.4 12.7 2.0 1 1 1 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EGG21479.1 - 3.9e-12 46.9 177.9 0.071 14.0 31.6 6.9 1 1 4 5 5 5 4 Nucleoporin FG repeat region Myosin_tail_1 PF01576.19 EGG21479.1 - 0.056 11.3 8.2 0.074 10.8 8.2 1.0 1 0 0 1 1 1 0 Myosin tail PCRF PF03462.18 EGG21479.1 - 0.23 11.3 5.8 0.43 10.4 5.8 1.4 1 0 0 1 1 1 0 PCRF domain DUF1664 PF07889.12 EGG21479.1 - 1.7 8.7 10.4 0.78 9.8 7.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EGG21479.1 - 3.8 8.0 6.2 7.9 7.0 1.6 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 EGG21479.1 - 5 7.1 12.7 4.3 7.4 6.4 2.2 1 1 1 2 2 2 0 Laminin Domain II ParB PF08775.10 EGG21479.1 - 5.7 7.4 11.0 1.2 9.6 1.3 2.4 1 1 1 2 2 2 0 ParB family DUF16 PF01519.16 EGG21479.1 - 7.9 7.0 14.4 6.2 7.4 5.8 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 EGG21479.1 - 9.2 6.4 14.2 6.7 6.9 11.9 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.7 EGG21480.1 - 2.4e-43 146.6 8.5 5.7e-12 46.1 0.4 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG21480.1 - 2.2e-41 139.7 12.1 4.7e-09 36.6 0.0 6.5 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG21480.1 - 6e-34 115.7 7.8 1.3e-09 38.2 0.1 5.3 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EGG21480.1 - 7.1e-32 108.5 12.2 1.8e-05 25.0 0.4 8.3 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 EGG21480.1 - 1.4e-29 98.8 3.0 0.0033 17.8 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Homeodomain PF00046.29 EGG21480.1 - 7.1e-18 64.2 0.1 7.1e-18 64.2 0.1 3.3 5 0 0 5 5 5 1 Homeodomain Dickkopf_N PF04706.12 EGG21481.1 - 0.0024 18.3 8.2 0.0024 18.3 8.2 6.5 4 2 1 6 6 6 2 Dickkopf N-terminal cysteine-rich region FAD_binding_8 PF08022.12 EGG21482.1 - 3.5e-27 94.6 0.1 9.1e-27 93.3 0.1 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EGG21482.1 - 4.5e-24 85.3 0.0 4.5e-24 85.3 0.0 2.8 3 2 0 3 3 3 1 Ferric reductase NAD binding domain EF-hand_7 PF13499.6 EGG21482.1 - 1.8e-11 44.3 2.5 4.5e-11 43.0 2.5 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGG21482.1 - 1.6e-09 36.9 3.7 0.00014 21.5 1.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGG21482.1 - 2.8e-09 35.9 3.8 1.5e-06 27.3 1.4 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGG21482.1 - 2.9e-08 33.4 2.2 5.4e-06 26.2 0.6 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG21482.1 - 1.1e-07 31.0 3.0 3.3e-07 29.5 1.3 2.4 2 0 0 2 2 2 1 EF hand FAD_binding_6 PF00970.24 EGG21482.1 - 0.0021 18.4 0.1 0.0071 16.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Ctr PF04145.15 EGG21482.1 - 0.23 12.1 0.1 0.23 12.1 0.1 3.6 3 1 0 3 3 3 0 Ctr copper transporter family GnsAB_toxin PF08178.11 EGG21483.1 - 0.024 14.6 0.1 0.046 13.6 0.1 1.5 1 1 0 1 1 1 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Gelsolin PF00626.22 EGG21484.1 - 1.5e-28 98.5 12.7 7.2e-10 38.6 0.0 6.8 7 0 0 7 7 7 5 Gelsolin repeat DUF2573 PF10835.8 EGG21485.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) KH_1 PF00013.29 EGG21486.1 - 1.4e-27 95.3 9.7 1.1e-13 50.8 0.6 2.5 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 EGG21486.1 - 6.2e-07 29.2 4.8 3.1e-05 23.8 0.3 2.9 3 0 0 3 3 3 2 KH domain Ank_4 PF13637.6 EGG21486.1 - 1.7e-06 28.4 0.0 0.0032 18.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG21486.1 - 0.00017 21.8 0.0 1 9.8 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG21486.1 - 0.00023 21.7 0.0 0.025 15.1 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) KH_2 PF07650.17 EGG21486.1 - 0.00026 20.7 12.1 0.048 13.5 0.4 3.3 1 1 1 3 3 3 2 KH domain Ank_3 PF13606.6 EGG21486.1 - 0.016 15.7 0.0 4.6 8.1 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat FTO_NTD PF12933.7 EGG21486.1 - 0.16 11.1 8.3 1.1 8.4 8.3 2.0 1 1 0 1 1 1 0 FTO catalytic domain CDC45 PF02724.14 EGG21486.1 - 0.33 9.2 15.8 0.59 8.4 15.8 1.3 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 EGG21486.1 - 6.3 5.5 17.8 12 4.6 17.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter RNA_pol_Rpb6 PF01192.22 EGG21488.1 - 2.6e-14 52.9 0.1 3.8e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Methyltransf_16 PF10294.9 EGG21489.1 - 3.4e-13 49.7 0.1 4.5e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase UPF0242 PF06785.11 EGG21490.1 - 0.066 13.3 11.7 0.11 12.5 11.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2951 PF11166.8 EGG21490.1 - 3.1 8.1 12.3 55 4.1 11.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Spc24 PF08286.11 EGG21490.1 - 3.7 7.8 16.6 0.061 13.6 8.2 2.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Got1 PF04178.12 EGG21491.1 - 8.8e-32 109.9 16.8 1.1e-31 109.6 16.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4064 PF13273.6 EGG21491.1 - 0.021 15.1 4.7 0.021 15.1 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) YwiC PF14256.6 EGG21491.1 - 0.1 12.9 5.1 0.12 12.7 5.1 1.2 1 0 0 1 1 1 0 YwiC-like protein Pox_A14 PF05767.12 EGG21491.1 - 2.2 8.5 9.9 0.071 13.3 1.4 2.4 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 7tm_3 PF00003.22 EGG21492.1 - 2.6e-32 112.4 28.3 2.6e-32 112.4 28.3 2.4 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR ALMT PF11744.8 EGG21492.1 - 2.7 6.7 13.6 5.9 5.6 13.6 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter Dapper PF15268.6 EGG21492.1 - 4 6.2 20.6 5.5 5.7 20.6 1.0 1 0 0 1 1 1 0 Dapper Vps39_1 PF10366.9 EGG21493.1 - 0.046 14.0 0.3 0.14 12.4 0.3 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Med30 PF11315.8 EGG21493.1 - 0.19 12.0 2.7 0.81 9.9 0.0 2.7 3 0 0 3 3 3 0 Mediator complex subunit 30 APG17 PF04108.12 EGG21493.1 - 0.24 10.5 0.1 0.24 10.5 0.1 2.3 3 0 0 3 3 3 0 Autophagy protein Apg17 APG6_N PF17675.1 EGG21493.1 - 1.4 9.5 7.3 5.8 7.5 0.4 3.1 3 0 0 3 3 3 0 Apg6 coiled-coil region Enkurin PF13864.6 EGG21493.1 - 1.5 9.3 5.5 1.5 9.3 0.0 3.0 3 1 0 3 3 3 0 Calmodulin-binding CBP_BcsQ PF06564.12 EGG21494.1 - 0.03 13.8 3.7 0.071 12.6 3.7 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ TPR_19 PF14559.6 EGG21494.1 - 0.092 13.3 1.8 0.18 12.4 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4100 PF13352.6 EGG21494.1 - 0.097 12.4 0.0 0.097 12.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4100) GAGA_bind PF06217.12 EGG21494.1 - 0.14 12.4 17.8 0.034 14.4 7.8 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family DUF948 PF06103.11 EGG21494.1 - 0.32 11.3 2.9 11 6.4 0.3 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PseudoU_synth_1 PF01416.20 EGG21495.1 - 1.6e-29 102.5 0.0 4.7e-25 88.1 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase PAXIP1_C PF15364.6 EGG21495.1 - 0.018 15.3 7.8 0.018 15.3 7.8 3.1 3 0 0 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein TOM20_plant PF06552.12 EGG21495.1 - 0.16 11.7 3.0 0.33 10.7 3.0 1.5 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 DUF572 PF04502.13 EGG21495.1 - 3.7 7.1 20.9 0.4 10.3 9.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF572) Vezatin PF12632.7 EGG21497.1 - 3.4e-11 43.0 4.7 3.4e-11 43.0 4.7 2.4 2 1 0 2 2 2 1 Mysoin-binding motif of peroxisomes PDDEXK_5 PF11645.8 EGG21497.1 - 0.062 13.3 1.2 0.17 11.9 0.1 2.4 3 0 0 3 3 3 0 PD-(D/E)XK endonuclease Mito_fiss_reg PF05308.11 EGG21497.1 - 0.44 10.6 10.1 0.059 13.5 4.8 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator PhoR PF11808.8 EGG21497.1 - 0.75 10.2 7.6 0.43 11.0 2.5 3.0 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR RhoGAP PF00620.27 EGG21498.1 - 1.3e-38 132.2 0.1 1.3e-38 132.2 0.1 1.5 2 0 0 2 2 2 1 RhoGAP domain ANAPC4_WD40 PF12894.7 EGG21498.1 - 0.04 14.2 0.1 8.7 6.7 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain BBS1 PF14779.6 EGG21498.1 - 0.13 11.6 0.0 11 5.3 0.0 2.2 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 1 Lactamase_B_6 PF16661.5 EGG21499.1 - 1e-23 83.8 0.0 3.8e-23 81.9 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 EGG21499.1 - 1.2e-22 80.3 0.1 5.5e-22 78.2 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 EGG21499.1 - 5.5e-19 67.9 0.0 1.1e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EGG21499.1 - 3.4e-11 43.5 0.0 4e-10 40.0 0.0 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGG21499.1 - 3.7e-09 36.4 0.1 1.8e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGG21499.1 - 0.0061 16.5 0.0 0.029 14.2 0.0 2.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain RANK_CRD_2 PF18278.1 EGG21499.1 - 0.06 13.5 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Exotox-A_cataly PF09009.10 EGG21500.1 - 9.9e-06 25.4 0.0 6.1e-05 22.8 0.0 2.3 3 0 0 3 3 3 1 Exotoxin A catalytic LupA PF18242.1 EGG21500.1 - 0.0078 15.9 0.0 0.033 13.9 0.0 1.9 2 0 0 2 2 2 1 Legionella ubiquitin-specific protease A domain LCE6A PF15858.5 EGG21500.1 - 0.11 13.3 0.6 1.2 9.9 0.2 2.6 2 0 0 2 2 2 0 Late cornified envelope protein 6A family CLN3 PF02487.17 EGG21501.1 - 2.3e-62 211.3 15.7 2.8e-62 211.1 15.7 1.0 1 0 0 1 1 1 1 CLN3 protein MACPF PF01823.19 EGG21502.1 - 5.9e-19 69.0 3.2 5.9e-19 69.0 3.2 2.1 2 1 0 2 2 2 1 MAC/Perforin domain PA14 PF07691.12 EGG21502.1 - 3.3e-06 27.0 0.1 1e-05 25.4 0.1 1.8 1 0 0 1 1 1 1 PA14 domain DUF1565 PF07602.11 EGG21502.1 - 0.0036 16.7 8.7 0.053 12.8 8.7 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) zf-RING_6 PF14835.6 EGG21502.1 - 0.64 9.9 3.0 1.3 9.0 1.9 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein MACPF PF01823.19 EGG21504.1 - 5.6e-18 65.8 4.1 1.4e-17 64.5 4.1 1.7 1 0 0 1 1 1 1 MAC/Perforin domain PA14 PF07691.12 EGG21504.1 - 0.00058 19.7 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 PA14 domain UQ_con PF00179.26 EGG21508.1 - 2.5e-37 127.6 0.1 4e-37 127.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGG21508.1 - 0.0033 17.7 0.7 0.0051 17.1 0.5 1.6 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EGG21508.1 - 0.0062 16.2 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF945 PF06097.11 EGG21508.1 - 0.16 11.0 0.4 0.2 10.7 0.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) GATA PF00320.27 EGG21509.1 - 1.6e-16 59.6 5.4 3.1e-16 58.7 5.4 1.5 1 0 0 1 1 1 1 GATA zinc finger PA28_beta PF02252.18 EGG21509.1 - 0.0016 18.2 1.3 0.0029 17.3 1.3 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit FAM76 PF16046.5 EGG21509.1 - 0.009 15.4 2.3 0.009 15.4 2.3 2.7 3 0 0 3 3 3 1 FAM76 protein NARP1 PF12569.8 EGG21509.1 - 0.012 14.6 1.9 0.025 13.5 1.9 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CNDH2_C PF16858.5 EGG21509.1 - 0.26 11.1 8.4 0.022 14.7 1.5 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term ABC_tran PF00005.27 EGG21511.1 - 1.9e-34 119.1 0.0 2e-16 60.7 0.0 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGG21511.1 - 3.8e-13 49.4 3.0 5e-05 22.9 0.2 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain RLI PF04068.15 EGG21511.1 - 9.9e-13 47.7 6.4 3e-12 46.1 6.4 1.9 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 EGG21511.1 - 2.4e-08 34.1 7.2 0.2 11.4 0.1 4.2 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 EGG21511.1 - 1.1e-07 31.4 2.6 1.1e-07 31.4 2.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 EGG21511.1 - 7.3e-06 26.4 0.0 0.04 14.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGG21511.1 - 8.4e-06 26.1 0.0 0.016 15.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Fer4_6 PF12837.7 EGG21511.1 - 1.4e-05 25.0 2.0 1.4e-05 25.0 2.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 EGG21511.1 - 1.9e-05 24.6 0.1 0.049 13.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGG21511.1 - 2.2e-05 24.9 0.0 0.16 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 EGG21511.1 - 0.00013 21.9 0.0 0.082 12.8 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 EGG21511.1 - 0.00022 21.4 0.1 0.13 12.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGG21511.1 - 0.00051 19.7 0.3 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EGG21511.1 - 0.00053 19.8 4.8 0.48 10.1 0.2 3.5 3 1 0 4 4 4 2 AAA ATPase domain NACHT PF05729.12 EGG21511.1 - 0.0006 19.8 0.1 0.46 10.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Fer4_2 PF12797.7 EGG21511.1 - 0.0013 18.7 1.1 0.0013 18.7 1.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain SRP54 PF00448.22 EGG21511.1 - 0.0019 17.8 3.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EGG21511.1 - 0.002 17.9 1.2 0.28 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EGG21511.1 - 0.0024 18.1 0.0 0.8 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGG21511.1 - 0.0027 18.1 0.0 2.3 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Fer4_21 PF14697.6 EGG21511.1 - 0.0036 17.4 12.5 0.008 16.3 12.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_14 PF13173.6 EGG21511.1 - 0.0044 17.1 0.2 1.4 9.0 0.0 3.4 4 0 0 4 4 3 1 AAA domain Fer4_9 PF13187.6 EGG21511.1 - 0.0068 16.6 10.4 0.015 15.5 10.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain TsaE PF02367.17 EGG21511.1 - 0.009 16.0 0.2 0.21 11.6 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 EGG21511.1 - 0.01 15.6 0.3 14 5.3 0.0 3.3 3 0 0 3 3 3 0 Thymidylate kinase Fer4_7 PF12838.7 EGG21511.1 - 0.01 16.4 1.8 0.01 16.4 1.8 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain AAA_23 PF13476.6 EGG21511.1 - 0.012 16.1 3.7 0.23 11.9 0.5 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGG21511.1 - 0.019 14.5 0.1 0.41 10.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Fer4_10 PF13237.6 EGG21511.1 - 0.02 15.0 1.4 0.02 15.0 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain TniB PF05621.11 EGG21511.1 - 0.023 14.1 0.0 8.1 5.8 0.0 3.1 2 1 1 3 3 3 0 Bacterial TniB protein AAA_30 PF13604.6 EGG21511.1 - 0.024 14.3 0.4 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGG21511.1 - 0.028 15.0 0.0 13 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGG21511.1 - 0.033 13.5 0.3 0.75 9.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Fer4_16 PF13484.6 EGG21511.1 - 0.044 14.7 0.2 0.044 14.7 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_5 PF07728.14 EGG21511.1 - 0.07 13.1 0.4 8.5 6.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) VirE PF05272.11 EGG21511.1 - 0.085 12.6 0.2 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E MMR_HSR1 PF01926.23 EGG21511.1 - 0.098 12.8 0.1 17 5.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EGG21511.1 - 0.12 11.5 1.2 5.1 6.2 0.1 2.5 2 1 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 EGG21511.1 - 0.14 11.2 0.0 6.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MeaB PF03308.16 EGG21511.1 - 0.22 10.5 0.1 1.9 7.4 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 EGG21511.1 - 0.25 10.7 0.5 0.79 9.1 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MobB PF03205.14 EGG21511.1 - 0.6 10.0 1.9 5.4 6.9 0.0 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 EGG21511.1 - 0.66 9.9 2.8 16 5.4 0.0 2.9 3 0 0 3 3 2 0 NTPase Fer4_8 PF13183.6 EGG21511.1 - 8.9 6.8 11.6 1.1 9.8 1.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain LIM PF00412.22 EGG21512.1 - 5.5e-09 36.1 9.0 8.8e-09 35.5 9.0 1.3 1 0 0 1 1 1 1 LIM domain Talin_middle PF09141.10 EGG21512.1 - 0.0041 17.2 7.7 0.25 11.4 1.0 3.1 1 1 1 2 2 2 1 Talin, middle domain DUF4665 PF15679.5 EGG21512.1 - 0.0065 17.1 11.0 0.07 13.7 0.6 3.8 1 1 3 4 4 4 2 Domain of unknown function (DUF4665) NinD PF17466.2 EGG21512.1 - 0.11 12.6 0.6 0.22 11.6 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function zf-ACC PF17848.1 EGG21512.1 - 0.17 12.0 5.7 2.1 8.5 0.8 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain RRM_1 PF00076.22 EGG21513.1 - 3.7e-07 29.9 0.1 9.1e-07 28.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG21513.1 - 0.0084 16.0 0.4 0.028 14.3 0.1 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif Phasin PF05597.11 EGG21513.1 - 2.4 8.2 11.6 0.25 11.4 3.1 2.8 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Pkinase PF00069.25 EGG21514.1 - 3.8e-46 157.6 0.1 1.2e-44 152.6 0.1 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21514.1 - 2.3e-32 112.3 0.0 1.1e-23 83.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGG21514.1 - 0.0087 15.4 0.0 0.082 12.2 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Ank_4 PF13637.6 EGG21515.1 - 0.026 15.1 0.1 4.8 7.9 0.0 3.7 3 1 1 4 4 4 0 Ankyrin repeats (many copies) CNTF PF01110.17 EGG21515.1 - 0.67 9.3 3.9 23 4.3 0.0 2.7 3 0 0 3 3 3 0 Ciliary neurotrophic factor Ctr PF04145.15 EGG21515.1 - 0.99 10.0 4.9 5.7 7.5 2.3 2.7 2 0 0 2 2 2 0 Ctr copper transporter family Arrestin_N PF00339.29 EGG21516.1 - 5e-14 52.6 0.2 5e-14 52.6 0.2 3.6 4 0 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGG21516.1 - 1.3e-10 41.8 32.3 1.5e-10 41.7 6.2 4.8 4 1 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 EGG21516.1 - 0.0033 17.2 0.2 0.007 16.1 0.2 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Arf PF00025.21 EGG21517.1 - 6.8e-78 260.1 0.2 1.1e-77 259.4 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG21517.1 - 2.4e-14 53.6 0.0 4.1e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGG21517.1 - 3.5e-14 52.6 0.0 5.4e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGG21517.1 - 8.4e-13 48.2 3.4 9.2e-10 38.2 0.4 2.7 2 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.22 EGG21517.1 - 6.5e-12 45.3 0.0 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGG21517.1 - 2.1e-11 43.6 0.1 3.8e-11 42.8 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG21517.1 - 3.7e-05 23.8 0.0 7.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGG21517.1 - 0.041 13.2 0.2 0.099 11.9 0.2 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DUF2971 PF11185.8 EGG21517.1 - 0.17 13.1 0.0 11 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2971) Vac14_Fig4_bd PF11916.8 EGG21518.1 - 8.5e-73 243.8 9.0 2.2e-72 242.5 9.0 1.8 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EGG21518.1 - 2.4e-46 156.3 0.1 3.2e-41 139.8 0.0 4.8 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGG21518.1 - 1.9e-11 43.2 3.8 0.0058 16.8 0.0 8.0 8 0 0 8 8 8 2 HEAT repeat CLASP_N PF12348.8 EGG21518.1 - 1.8e-06 27.7 0.5 1.9 8.0 0.0 4.6 3 1 0 4 4 4 3 CLASP N terminal Cnd1 PF12717.7 EGG21518.1 - 5.9e-06 26.4 9.1 0.091 12.8 0.2 4.2 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGG21518.1 - 1.4e-05 25.4 0.0 0.43 11.0 0.0 4.7 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EGG21518.1 - 2.2e-05 24.8 0.2 1.8 9.1 0.0 5.0 5 0 0 5 5 5 2 HEAT-like repeat RTP1_C1 PF10363.9 EGG21518.1 - 0.0094 16.1 0.6 9.8 6.4 0.1 3.6 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Nipped-B_C PF12830.7 EGG21518.1 - 0.041 13.8 0.1 2 8.3 0.0 2.9 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus Arm PF00514.23 EGG21518.1 - 0.067 13.3 0.2 13 6.0 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat UTP25 PF06862.12 EGG21519.1 - 1.1e-158 529.0 8.0 1.4e-158 528.6 8.0 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_C PF00271.31 EGG21519.1 - 0.83 10.0 2.7 1.1 9.6 0.0 2.7 3 1 0 3 3 3 0 Helicase conserved C-terminal domain TFIIA PF03153.13 EGG21520.1 - 0.0041 17.2 18.8 0.0041 17.2 18.8 5.2 3 1 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit PRIMA1 PF16101.5 EGG21521.1 - 0.042 13.9 5.0 0.06 13.4 5.0 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF1180 PF06679.12 EGG21521.1 - 0.042 14.3 1.2 0.046 14.1 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Mito_fiss_reg PF05308.11 EGG21521.1 - 0.076 13.1 4.7 0.09 12.9 4.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator IMD PF08397.11 EGG21522.1 - 9.5e-16 57.8 6.0 1.2e-15 57.5 6.0 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_1 PF00018.28 EGG21522.1 - 3.5e-14 52.1 0.0 7.3e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGG21522.1 - 2.4e-10 40.1 0.0 4.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGG21522.1 - 2.9e-09 36.5 0.0 5.9e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 EGG21522.1 - 2.2e-05 24.3 8.6 5.8e-05 22.9 8.6 1.7 1 1 0 1 1 1 1 BAR domain of APPL family DUF4745 PF15923.5 EGG21522.1 - 0.0012 18.9 0.0 0.056 13.4 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4745) Cytochrom_B562 PF07361.11 EGG21522.1 - 0.078 13.6 5.2 0.089 13.5 2.2 2.5 1 1 2 3 3 3 0 Cytochrome b562 CCD PF07860.11 EGG21522.1 - 0.5 10.4 4.9 0.76 9.8 0.1 2.7 2 1 1 3 3 3 0 WisP family C-Terminal Region CC190 PF15768.5 EGG21522.1 - 1.5 8.8 9.8 0.57 10.2 4.9 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 190 Jnk-SapK_ap_N PF09744.9 EGG21522.1 - 7.8 6.7 13.0 11 6.2 11.6 2.1 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Dicty_CAR PF05462.11 EGG21523.1 - 6.1e-128 426.2 26.9 6.1e-128 426.2 26.9 1.3 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 EGG21523.1 - 4.9e-10 39.1 21.3 7.4e-10 38.5 21.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF1129 PF06570.11 EGG21523.1 - 0.0005 19.6 2.3 0.0011 18.5 2.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) SpoIIM PF01944.17 EGG21523.1 - 0.085 12.9 8.7 2.1 8.3 7.9 2.6 1 1 0 1 1 1 0 Stage II sporulation protein M Wzy_C_2 PF11846.8 EGG21523.1 - 0.1 12.5 1.3 0.32 10.9 0.3 2.1 1 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF3325 PF11804.8 EGG21523.1 - 0.64 10.2 5.7 0.24 11.6 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3325) 7tm_1 PF00001.21 EGG21523.1 - 1.3 8.3 20.7 2.3 7.5 20.7 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) PDEase_II PF02112.15 EGG21524.1 - 3e-70 237.0 0.1 3.7e-70 236.7 0.1 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II FAM76 PF16046.5 EGG21525.1 - 0.0028 17.1 4.4 0.0031 16.9 4.4 1.1 1 0 0 1 1 1 1 FAM76 protein Cnn_1N PF07989.11 EGG21525.1 - 0.0044 17.1 1.5 0.0044 17.1 1.5 1.8 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 Med9 PF07544.13 EGG21525.1 - 0.0055 16.8 4.1 0.024 14.7 4.1 2.0 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF1192 PF06698.11 EGG21525.1 - 0.015 15.4 4.5 0.026 14.6 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) ABC_tran_CTD PF16326.5 EGG21525.1 - 0.03 14.5 2.5 0.03 14.5 2.5 1.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain Pox_A_type_inc PF04508.12 EGG21525.1 - 0.082 12.8 0.2 0.082 12.8 0.2 2.3 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat YabA PF06156.13 EGG21525.1 - 0.13 12.9 1.8 0.21 12.2 0.9 1.8 1 1 1 2 2 2 0 Initiation control protein YabA DUF4094 PF13334.6 EGG21525.1 - 0.44 11.0 2.5 0.21 12.0 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) XhlA PF10779.9 EGG21525.1 - 2.3 8.5 6.3 0.73 10.1 2.6 2.0 2 0 0 2 2 2 0 Haemolysin XhlA DUF4795 PF16043.5 EGG21525.1 - 8 6.0 12.1 2.4 7.7 5.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Ank_2 PF12796.7 EGG21526.1 - 5.5e-37 126.2 0.5 4e-11 43.3 0.1 3.6 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG21526.1 - 7.7e-37 124.9 3.9 4.3e-07 30.1 0.0 5.4 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EGG21526.1 - 4.2e-34 115.5 8.1 4.1e-06 27.0 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EGG21526.1 - 1.9e-32 107.6 6.3 2.1e-05 24.6 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 EGG21526.1 - 5.2e-29 100.2 7.7 3.8e-11 43.3 0.1 5.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) PUCC PF03209.15 EGG21526.1 - 0.037 13.0 0.3 0.051 12.6 0.3 1.1 1 0 0 1 1 1 0 PUCC protein DUF702 PF05142.12 EGG21526.1 - 0.11 13.0 3.5 0.19 12.2 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) CPSF100_C PF13299.6 EGG21526.1 - 0.19 11.9 2.9 0.35 11.0 2.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal O-antigen_lig PF13425.6 EGG21526.1 - 3.4 6.3 6.8 4.5 5.9 6.8 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Cyt-b5 PF00173.28 EGG21528.1 - 3.3e-15 56.0 0.1 7.1e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 EGG21528.1 - 3.4e-14 53.3 30.8 5.2e-13 49.4 16.6 2.8 2 1 0 2 2 2 2 Fatty acid desaturase DUF3915 PF13054.6 EGG21529.1 - 0.071 13.1 3.5 0.3 11.1 4.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Apis_Csd PF11671.8 EGG21529.1 - 0.08 13.0 3.3 0.14 12.1 3.3 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein DUF2058 PF09831.9 EGG21529.1 - 0.19 11.9 2.1 0.27 11.4 2.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) TMEM171 PF15471.6 EGG21529.1 - 0.23 10.4 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 Atrophin-1 PF03154.15 EGG21529.1 - 1.1 7.4 6.0 1.4 7.1 6.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3683 PF12447.8 EGG21531.1 - 0.012 15.8 0.8 6.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) E1_UFD PF09358.10 EGG21531.1 - 9.5 7.0 7.2 70 4.2 0.0 3.3 3 1 0 3 3 3 0 Ubiquitin fold domain Acetyltransf_4 PF13420.7 EGG21532.1 - 5.9e-20 72.0 0.2 6.4e-12 45.9 0.0 2.0 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG21532.1 - 2e-09 37.7 0.0 2.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGG21532.1 - 4e-05 23.5 0.0 6.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EGG21532.1 - 0.00014 22.5 0.0 0.00019 22.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG21532.1 - 0.00018 21.5 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EGG21532.1 - 0.00027 20.6 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase tRNA-Thr_ED PF08915.11 EGG21532.1 - 0.059 13.4 0.0 0.09 12.8 0.0 1.2 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase DOCK-C2 PF14429.6 EGG21533.1 - 1e-47 162.5 2.2 1.8e-46 158.4 3.1 2.8 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 EGG21533.1 - 2e-05 24.9 1.4 8.4e-05 23.0 1.4 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) DHR-2 PF06920.13 EGG21534.1 - 3.5e-89 299.8 3.8 4.2e-89 299.6 3.8 1.1 1 0 0 1 1 1 1 Dock homology region 2 SMODS PF18144.1 EGG21534.1 - 0.42 10.8 3.4 30 4.7 0.5 3.2 3 0 0 3 3 3 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain DPBB_1 PF03330.18 EGG21536.1 - 9.5e-09 35.4 0.9 7.4e-08 32.6 0.3 2.7 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 EGG21536.1 - 0.00062 19.6 0.5 0.0014 18.5 0.2 1.7 1 1 0 1 1 1 1 Barwin family Cerato-platanin PF07249.12 EGG21536.1 - 0.0023 18.0 0.2 0.0046 17.1 0.2 1.5 1 0 0 1 1 1 1 Cerato-platanin Keratin_matx PF04579.12 EGG21536.1 - 0.01 16.2 0.4 0.034 14.5 0.2 2.1 2 0 0 2 2 2 0 Keratin, high-sulphur matrix protein Redoxin PF08534.10 EGG21536.1 - 0.051 13.3 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Redoxin Kinesin PF00225.23 EGG21537.1 - 2.1e-63 214.2 0.7 2.1e-63 214.2 0.7 2.9 3 1 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EGG21537.1 - 8.6e-19 67.9 0.1 8.6e-19 67.9 0.1 3.1 2 1 0 2 2 2 1 Microtubule binding SAM_1 PF00536.30 EGG21537.1 - 9.6e-08 32.4 0.1 3e-07 30.8 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CARMIL_C PF16000.5 EGG21537.1 - 5.8e-06 26.1 1.3 5.8e-06 26.1 1.3 3.7 2 2 0 3 3 3 2 CARMIL C-terminus SAM_2 PF07647.17 EGG21537.1 - 1.8e-05 24.7 0.1 6.2e-05 23.0 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Activator_LAG-3 PF11498.8 EGG21537.1 - 0.0018 17.3 61.4 0.0018 17.3 61.4 4.4 4 0 0 4 4 4 1 Transcriptional activator LAG-3 DUF2828 PF11443.8 EGG21537.1 - 0.005 15.0 19.5 0.0083 14.3 19.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) AcetylCoA_hydro PF02550.15 EGG21537.1 - 0.19 11.7 4.6 19 5.1 0.0 2.3 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase N-terminal domain LMBR1 PF04791.16 EGG21537.1 - 1.3 7.8 12.8 2.6 6.8 12.8 1.6 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2723 PF11028.8 EGG21538.1 - 6.9e-37 127.0 8.9 6.9e-37 127.0 8.9 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2723) Ribosomal_L23 PF00276.20 EGG21539.1 - 9.5e-17 61.1 0.7 1.4e-16 60.6 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 GPR_Gpa2_C PF11970.8 EGG21540.1 - 0.053 13.6 0.2 0.053 13.6 0.2 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Frizzled PF01534.17 EGG21540.1 - 0.33 9.9 16.9 0.036 13.1 6.6 2.6 2 1 1 3 3 3 0 Frizzled/Smoothened family membrane region TPR_1 PF00515.28 EGG21541.1 - 5e-18 64.1 5.7 0.00034 20.3 0.1 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGG21541.1 - 1.4e-16 59.2 3.3 0.0011 19.0 0.1 5.8 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGG21541.1 - 1.5e-13 50.8 5.0 1.2e-05 25.4 0.1 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG21541.1 - 1.8e-12 46.4 3.1 0.00016 21.6 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG21541.1 - 8.3e-11 41.8 0.2 0.0037 18.0 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG21541.1 - 1.1e-09 38.3 1.2 0.46 11.2 0.0 5.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG21541.1 - 1.3e-09 38.6 0.0 0.015 15.9 0.0 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG21541.1 - 3.1e-09 37.2 0.2 0.074 13.6 0.0 4.1 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG21541.1 - 6.2e-08 32.1 4.0 0.051 13.6 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG21541.1 - 7e-08 32.6 3.7 0.086 13.1 0.1 4.3 1 1 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EGG21541.1 - 2.1e-05 24.1 1.0 11 5.8 0.0 5.9 6 0 0 6 6 6 0 TPR repeat TPR_10 PF13374.6 EGG21541.1 - 0.0001 22.0 1.8 5.3 7.1 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG21541.1 - 0.00011 22.3 2.2 18 6.0 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Thioredoxin_5 PF13743.6 EGG21541.1 - 0.0011 18.7 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin TPR_MalT PF17874.1 EGG21541.1 - 0.002 17.5 0.5 1.4 8.2 0.1 2.4 2 1 0 2 2 2 2 MalT-like TPR region DUF5588 PF17826.1 EGG21541.1 - 0.026 13.4 0.0 0.047 12.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5588) SRP_TPR_like PF17004.5 EGG21541.1 - 0.063 13.3 1.9 0.54 10.3 0.0 2.8 2 2 0 2 2 2 0 Putative TPR-like repeat TPR_15 PF13429.6 EGG21541.1 - 0.079 12.2 0.4 0.67 9.1 0.1 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat LBP_BPI_CETP PF01273.25 EGG21542.1 - 0.024 14.2 0.2 0.54 9.9 0.1 2.5 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain PSII_Pbs31 PF18240.1 EGG21542.1 - 0.79 10.2 5.4 3.7 8.1 0.2 3.2 1 1 2 3 3 3 0 Photosystem II Psb31 protein Pico_P2B PF01552.17 EGG21542.1 - 0.82 9.9 6.5 4.9 7.4 0.3 2.8 3 0 0 3 3 3 0 Picornavirus 2B protein PAH PF02671.21 EGG21542.1 - 1.1 9.5 3.6 0.9 9.7 0.5 2.6 2 1 0 2 2 2 0 Paired amphipathic helix repeat TipAS PF07739.13 EGG21542.1 - 1.1 9.8 8.5 1.5 9.4 1.4 4.0 2 1 2 4 4 4 0 TipAS antibiotic-recognition domain DUF1771 PF08590.10 EGG21542.1 - 1.9 8.9 4.2 1.1 9.7 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) DUF2283 PF10049.9 EGG21542.1 - 2.9 8.2 5.1 31 4.9 1.9 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2283) Clat_adaptor_s PF01217.20 EGG21543.1 - 5.2e-07 29.7 2.0 1.1e-06 28.6 2.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain 7tm_3 PF00003.22 EGG21544.1 - 2.8e-33 115.6 11.4 4.7e-33 114.9 11.4 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 EGG21544.1 - 2.9e-06 26.5 0.6 5.4e-06 25.6 0.6 1.4 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like zf-C2H2_3 PF13878.6 EGG21545.1 - 1.1e-15 57.1 1.1 2.6e-15 56.0 1.1 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_13 PF13880.6 EGG21545.1 - 5.8e-06 26.2 0.2 1.1e-05 25.3 0.2 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase DUF4746 PF15928.5 EGG21545.1 - 0.034 13.6 5.0 0.15 11.5 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) FAM176 PF14851.6 EGG21545.1 - 0.18 11.5 10.8 1.4 8.6 2.7 2.6 2 0 0 2 2 2 0 FAM176 family GNAT_acetyltr_2 PF13718.6 EGG21545.1 - 3.8 6.9 6.9 9.1 5.6 3.5 2.3 2 0 0 2 2 2 0 GNAT acetyltransferase 2 CENP-B_dimeris PF09026.10 EGG21545.1 - 5.1 7.6 11.7 8.9 6.8 6.0 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Ribonuc_P_40 PF08584.11 EGG21546.1 - 1.3e-66 224.8 0.2 1.3e-66 224.8 0.2 2.1 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit Macoilin PF09726.9 EGG21546.1 - 1.5 7.3 12.9 0.16 10.5 7.2 1.9 2 0 0 2 2 2 0 Macoilin family DUF5345 PF17280.2 EGG21547.1 - 0.14 12.2 0.0 0.57 10.2 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Arc_PepC_II PF06847.11 EGG21547.1 - 0.15 12.6 0.1 0.42 11.1 0.1 1.6 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Col_cuticle_N PF01484.17 EGG21547.1 - 8.4 6.5 6.0 39 4.4 2.3 2.8 2 1 0 2 2 2 0 Nematode cuticle collagen N-terminal domain ATP_synt_H PF05493.13 EGG21548.1 - 1.3e-13 51.2 2.0 1.5e-13 51.0 2.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit H FecCD PF01032.18 EGG21548.1 - 0.029 13.4 0.6 0.033 13.2 0.6 1.0 1 0 0 1 1 1 0 FecCD transport family BRICHOS PF04089.14 EGG21548.1 - 0.15 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 BRICHOS domain OppC_N PF12911.7 EGG21548.1 - 0.16 12.0 1.1 1.5 8.9 0.1 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF2157 PF09925.9 EGG21548.1 - 0.26 11.1 2.4 0.28 11.0 2.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) PP2C_2 PF13672.6 EGG21549.1 - 0.029 14.0 0.0 0.16 11.6 0.0 2.2 2 1 0 2 2 2 0 Protein phosphatase 2C DUF2397 PF09660.10 EGG21549.1 - 0.19 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Brix PF04427.18 EGG21550.1 - 6.6e-42 143.8 0.0 1e-41 143.2 0.0 1.3 1 0 0 1 1 1 1 Brix domain RCC1 PF00415.18 EGG21551.1 - 4.2e-53 177.8 16.6 1.6e-08 35.1 0.1 8.8 8 1 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG21551.1 - 2.3e-32 110.1 33.1 1.8e-10 40.3 1.9 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat GOLD_2 PF13897.6 EGG21551.1 - 0.045 14.3 0.2 6.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Pep1_7 PF17232.2 EGG21551.1 - 7.8 7.0 10.8 21 5.7 3.7 3.2 3 0 0 3 3 3 0 Elicitor peptide 1-7 HAD_2 PF13419.6 EGG21552.1 - 8.8e-07 29.2 0.0 1.2e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG21552.1 - 6.8e-06 26.5 0.0 0.00046 20.5 0.0 2.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase FYVE PF01363.21 EGG21553.1 - 4.4e-06 26.7 12.2 1.5e-05 25.0 12.2 1.9 1 0 0 1 1 1 1 FYVE zinc finger DUF4806 PF16064.5 EGG21553.1 - 2.7 8.3 6.7 1.8 8.9 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) Mito_carr PF00153.27 EGG21554.1 - 8.2e-70 230.8 2.7 4.7e-23 80.9 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Pex16 PF08610.10 EGG21554.1 - 2.8e-39 135.2 0.5 8.1e-39 133.7 0.5 1.6 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) LapA_dom PF06305.11 EGG21554.1 - 0.077 12.8 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain bcl-2I13 PF12201.8 EGG21554.1 - 0.19 11.6 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing Acetyltransf_9 PF13527.7 EGG21555.1 - 1.3e-06 28.5 0.0 1.1e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG21555.1 - 0.004 17.4 0.0 0.0085 16.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG21555.1 - 0.025 15.0 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HEAT PF02985.22 EGG21556.1 - 7.3e-07 28.9 1.2 0.51 10.8 0.1 5.2 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 EGG21556.1 - 4.1e-06 26.9 4.8 0.039 14.0 0.5 3.9 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 EGG21556.1 - 7.2e-06 25.9 1.2 3.1 7.8 0.1 5.6 5 0 0 5 5 5 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 EGG21556.1 - 0.00049 20.7 3.4 0.055 14.1 0.1 3.7 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGG21556.1 - 0.0047 16.5 0.2 0.0047 16.5 0.2 2.3 3 0 0 3 3 3 1 CLASP N terminal Tti2 PF10521.9 EGG21556.1 - 0.023 14.3 1.9 1.2 8.6 0.0 3.2 4 0 0 4 4 4 0 Tti2 family Cnd3 PF12719.7 EGG21556.1 - 0.085 12.0 3.8 0.1 11.7 0.7 2.6 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 EGG21556.1 - 0.12 12.6 0.9 55 4.0 0.0 4.1 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Imm41 PF15592.6 EGG21556.1 - 1.2 9.5 4.3 7.8 6.9 0.3 3.7 4 0 0 4 4 4 0 Immunity protein 41 VWA_2 PF13519.6 EGG21557.1 - 1e-20 74.4 0.0 6e-20 71.9 0.0 2.3 1 1 1 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EGG21557.1 - 5.3e-08 33.3 0.6 8.1e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.20 EGG21557.1 - 9e-07 28.4 7.8 0.00047 19.9 1.8 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif Ssl1 PF04056.14 EGG21557.1 - 0.00021 21.2 0.4 0.00042 20.2 0.1 1.6 2 0 0 2 2 2 1 Ssl1-like DUF4362 PF14275.6 EGG21557.1 - 0.0034 17.6 1.3 0.0074 16.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4362) Fer4_14 PF13394.6 EGG21557.1 - 0.096 12.8 0.2 0.41 10.8 0.0 2.1 2 1 0 2 2 2 0 4Fe-4S single cluster domain Presenilin PF01080.17 EGG21557.1 - 9.2 4.9 5.7 12 4.5 5.7 1.2 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 EGG21558.1 - 4.5e-24 84.8 0.1 9.1e-11 42.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG21558.1 - 4.2e-21 75.0 0.0 1.1e-08 35.4 0.0 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGG21558.1 - 9.9e-18 63.7 0.2 6.2e-06 26.4 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EGG21558.1 - 2.1e-17 61.4 0.0 0.0016 18.8 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EGG21558.1 - 4.3e-17 62.0 0.1 1.1e-07 31.9 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Lzipper-MIP1 PF14389.6 EGG21558.1 - 0.0011 19.3 0.1 0.0021 18.3 0.1 1.4 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Snapin_Pallidin PF14712.6 EGG21558.1 - 0.0015 18.9 1.1 0.003 17.9 1.1 1.4 1 0 0 1 1 1 1 Snapin/Pallidin DUF4296 PF14129.6 EGG21558.1 - 0.0098 16.5 2.1 0.25 12.0 0.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4296) DUF2400 PF09674.10 EGG21558.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Prefoldin PF02996.17 EGG21558.1 - 1 9.3 4.0 11 5.9 0.1 2.7 3 0 0 3 3 3 0 Prefoldin subunit PAP_assoc PF03828.19 EGG21559.1 - 4.1e-17 62.1 0.6 2.1e-16 59.9 0.6 2.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGG21559.1 - 5.2e-08 33.1 0.0 5.2e-08 33.1 0.0 3.2 3 0 0 3 3 3 1 Nucleotidyltransferase domain Polbeta PF18765.1 EGG21559.1 - 0.00012 22.0 0.0 0.00012 22.0 0.0 3.3 4 0 0 4 4 4 1 Polymerase beta, Nucleotidyltransferase T7SS_ESX_EspC PF10824.8 EGG21559.1 - 0.1 13.1 0.5 0.59 10.6 0.1 2.4 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm MAGE_N PF12440.8 EGG21559.1 - 0.19 12.4 21.3 0.17 12.6 6.3 3.5 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal Auts2 PF15336.6 EGG21559.1 - 1.7 8.7 8.7 6.1 6.9 8.7 1.9 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Glycos_transf_1 PF00534.20 EGG21560.1 - 6.1e-27 94.2 0.0 2.6e-23 82.4 0.0 2.8 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 EGG21560.1 - 5.7e-26 91.3 0.3 2.4e-25 89.3 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_trans_1_4 PF13692.6 EGG21560.1 - 1.3e-18 67.7 0.0 3.1e-18 66.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_tranf_2_2 PF10111.9 EGG21560.1 - 2.7e-13 50.1 0.2 1.1e-12 48.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 EGG21560.1 - 6.1e-09 36.1 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGG21560.1 - 0.0061 16.5 0.0 0.062 13.2 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Rsc14 PF08586.10 EGG21560.1 - 0.0089 16.8 1.8 0.0089 16.8 1.8 3.5 4 0 0 4 4 4 1 RSC complex, Rsc14/Ldb7 subunit Glyco_trans_1_2 PF13524.6 EGG21560.1 - 0.13 12.6 0.1 0.71 10.3 0.0 2.3 3 0 0 3 3 3 0 Glycosyl transferases group 1 BTV_NS2 PF04514.12 EGG21560.1 - 2 7.2 7.7 3.6 6.3 7.7 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 60KD_IMP PF02096.20 EGG21561.1 - 2.2e-23 83.0 2.8 3.5e-23 82.3 2.8 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein WD40 PF00400.32 EGG21563.1 - 1.6e-17 63.5 10.6 0.00051 20.8 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG21563.1 - 3.6e-06 27.2 0.4 0.28 11.5 0.0 4.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG21563.1 - 0.0016 17.1 3.8 0.58 8.7 0.4 3.3 3 1 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EGG21563.1 - 0.0037 16.9 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain RB_A PF01858.17 EGG21563.1 - 0.41 10.4 2.6 1 9.2 2.6 1.6 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain DDHD PF02862.17 EGG21563.1 - 1.2 9.3 7.3 6.2 6.9 1.0 2.2 2 0 0 2 2 2 0 DDHD domain DUF913 PF06025.12 EGG21563.1 - 4.6 6.1 12.6 0.21 10.5 1.6 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) COMM_domain PF07258.14 EGG21567.1 - 2e-14 53.5 0.1 4.8e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 COMM domain DUF3755 PF12579.8 EGG21567.1 - 0.0081 15.8 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3755) TMEM234 PF10639.9 EGG21567.1 - 0.07 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Putative transmembrane family 234 RabGAP-TBC PF00566.18 EGG21568.1 - 4.4e-54 183.4 4.0 1e-53 182.2 4.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 EGG21568.1 - 6e-19 68.4 0.7 1.5e-10 41.5 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG21568.1 - 9.4e-12 44.0 0.2 0.2 12.3 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EGG21568.1 - 1.6e-10 41.0 3.1 0.025 15.0 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EGG21568.1 - 1.8e-10 41.1 1.4 0.00066 20.2 0.0 4.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG21568.1 - 1.1e-07 31.9 0.7 0.025 14.9 0.3 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) PEPCK_ATP PF01293.20 EGG21569.1 - 5.6e-19 68.2 0.2 1.7e-08 33.6 0.0 2.8 2 1 0 2 2 2 2 Phosphoenolpyruvate carboxykinase DUF4313 PF14190.6 EGG21569.1 - 0.13 12.3 0.6 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4313) PH PF00169.29 EGG21570.1 - 8.8e-26 90.5 2.8 7.6e-17 61.7 0.2 2.8 2 0 0 2 2 2 2 PH domain LIM PF00412.22 EGG21570.1 - 1.9e-22 79.2 35.9 2.5e-10 40.4 11.7 3.5 3 0 0 3 3 3 3 LIM domain PH_11 PF15413.6 EGG21570.1 - 4.3e-07 30.3 13.6 0.00047 20.6 0.2 4.0 3 1 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 EGG21570.1 - 0.00018 21.9 2.4 0.19 12.1 0.2 3.4 3 1 0 3 3 3 2 Pleckstrin homology domain DUF3127 PF11325.8 EGG21570.1 - 0.033 14.4 0.3 18 5.7 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3127) PRRSV_Env PF02340.15 EGG21570.1 - 0.11 11.9 0.2 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 PRRSV putative envelope protein B_lectin PF01453.24 EGG21571.1 - 3.4e-11 43.6 0.5 0.0037 17.8 0.1 4.2 2 2 2 4 4 4 4 D-mannose binding lectin BofC_C PF08955.10 EGG21571.1 - 0.014 15.4 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 BofC C-terminal domain DUF2206 PF09971.9 EGG21572.1 - 0.11 11.2 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Toxin_13 PF07822.11 EGG21572.1 - 0.14 12.3 5.8 0.27 11.4 5.6 1.7 1 1 0 1 1 1 0 Neurotoxin B-IV-like protein Roc PF08477.13 EGG21573.1 - 3.4e-06 27.3 3.1 1.4e-05 25.3 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG21573.1 - 0.00032 20.3 1.3 0.0044 16.6 0.0 2.4 2 0 0 2 2 2 1 Ras family Arf PF00025.21 EGG21573.1 - 0.0007 19.1 0.3 0.081 12.4 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 EGG21573.1 - 0.003 17.0 0.6 0.1 12.0 0.0 2.8 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGG21573.1 - 0.01 15.9 0.5 0.01 15.9 0.5 2.9 3 1 0 3 3 3 0 50S ribosome-binding GTPase MAP17 PF15807.5 EGG21573.1 - 0.067 13.4 0.2 0.067 13.4 0.2 3.2 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Acetyltransf_9 PF13527.7 EGG21574.1 - 7.4e-06 26.1 0.3 5.6e-05 23.2 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG21574.1 - 0.0038 17.4 0.0 0.0091 16.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG21574.1 - 0.035 14.5 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Bot1p PF12298.8 EGG21575.1 - 1.7e-05 25.1 0.0 5.9e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein TFIIA PF03153.13 EGG21576.1 - 0.017 15.2 21.7 0.022 14.8 21.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 EGG21576.1 - 0.047 13.0 17.3 0.031 13.6 6.1 2.1 2 0 0 2 2 2 0 NOA36 protein DUF2706 PF10913.8 EGG21576.1 - 0.27 11.1 2.9 0.71 9.8 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2706) Cwf_Cwc_15 PF04889.12 EGG21576.1 - 2.6 7.7 28.6 1.1 8.9 11.6 2.1 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein COPI_C PF06957.11 EGG21576.1 - 5 5.8 12.3 0.34 9.6 3.3 2.1 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Ras PF00071.22 EGG21577.1 - 6.8e-33 113.6 0.0 8.1e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG21577.1 - 5.5e-25 87.9 0.0 8e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG21577.1 - 7.5e-12 45.0 0.0 1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG21577.1 - 1.7e-06 28.1 0.0 2.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGG21577.1 - 1.7e-06 27.6 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGG21577.1 - 9.4e-05 21.9 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 EGG21577.1 - 0.003 17.0 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein FeoB_N PF02421.18 EGG21577.1 - 0.0048 16.4 0.0 0.012 15.2 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B NTPase_1 PF03266.15 EGG21577.1 - 0.0056 16.6 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 NTPase AAA_7 PF12775.7 EGG21577.1 - 0.028 13.9 0.1 0.053 13.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EGG21577.1 - 0.034 14.5 0.0 0.082 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EGG21577.1 - 0.055 13.9 0.0 0.079 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGG21577.1 - 0.082 13.2 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Branch PF02485.21 EGG21578.1 - 2.4e-13 50.2 8.0 2.9e-08 33.5 3.6 2.5 2 0 0 2 2 2 2 Core-2/I-Branching enzyme DUF2521 PF10730.9 EGG21578.1 - 0.039 14.0 0.1 0.098 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) EGF_2 PF07974.13 EGG21578.1 - 0.67 10.4 8.8 1.5 9.3 8.8 1.6 1 0 0 1 1 1 0 EGF-like domain ArAE_1_C PF11728.8 EGG21578.1 - 0.96 9.4 5.3 0.24 11.4 1.3 2.0 3 0 0 3 3 3 0 Putative aromatic acid exporter C-terminal domain Glyco_transf_10 PF00852.19 EGG21579.1 - 3.4e-34 118.1 1.2 6.6e-34 117.2 1.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term DUF2536 PF10750.9 EGG21579.1 - 0.019 14.8 0.0 0.17 11.8 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2536) Pkinase PF00069.25 EGG21580.1 - 3.8e-66 223.2 0.0 5e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21580.1 - 7.7e-26 90.9 0.0 1.1e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 EGG21580.1 - 4e-06 27.0 0.2 4.3e-05 23.7 0.2 2.2 1 1 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 EGG21580.1 - 0.00025 21.7 0.2 0.00098 19.8 0.2 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGG21580.1 - 0.0089 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PI3K_C2 PF00792.24 EGG21580.1 - 0.018 14.9 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 CHAP PF05257.16 EGG21580.1 - 0.06 13.9 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 CHAP domain Kdo PF06293.14 EGG21580.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG21580.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family REJ PF02010.15 EGG21581.1 - 2.3e-43 148.6 4.8 5.3e-40 137.6 2.0 2.3 1 1 1 2 2 2 2 REJ domain Glycos_transf_2 PF00535.26 EGG21581.1 - 1.4e-26 93.4 0.2 3.5e-26 92.0 0.2 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 GPS PF01825.21 EGG21581.1 - 5.6e-13 49.2 3.8 1.5e-12 47.8 3.8 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Glyco_tranf_2_2 PF10111.9 EGG21581.1 - 1.6e-12 47.5 0.5 1.5e-11 44.3 0.4 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_4 PF13439.6 EGG21581.1 - 1.5e-11 44.6 0.0 3.1e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 TIG PF01833.24 EGG21581.1 - 1.9e-10 40.7 5.9 1.9e-10 40.7 5.9 3.6 3 0 0 3 3 2 1 IPT/TIG domain Glyco_tranf_2_3 PF13641.6 EGG21581.1 - 2.7e-09 37.3 0.0 6.9e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_1 PF00534.20 EGG21581.1 - 1.2e-07 31.5 0.0 6e-06 25.9 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGG21581.1 - 1.5e-07 32.0 0.0 2.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_7C PF02709.14 EGG21581.1 - 0.00026 20.6 0.0 0.0007 19.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase HEXIM PF15313.6 EGG21581.1 - 0.0021 18.3 1.1 0.0054 16.9 1.1 1.6 1 0 0 1 1 1 1 Hexamethylene bis-acetamide-inducible protein Glyco_transf_5 PF08323.11 EGG21581.1 - 0.008 15.9 0.1 0.24 11.1 0.1 2.7 2 1 1 3 3 3 1 Starch synthase catalytic domain TMEM51 PF15345.6 EGG21581.1 - 0.012 15.4 1.4 0.023 14.5 1.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Glyco_trans_4_2 PF13477.6 EGG21581.1 - 0.02 14.9 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like MMM1 PF10296.9 EGG21581.1 - 0.025 13.6 2.5 0.054 12.6 2.5 1.5 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 RGCC PF15151.6 EGG21581.1 - 0.074 13.3 0.3 14 5.9 0.1 2.7 2 0 0 2 2 2 0 Response gene to complement 32 protein family DUF5316 PF17247.2 EGG21581.1 - 0.086 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5316) EphA2_TM PF14575.6 EGG21581.1 - 0.11 13.4 0.0 0.26 12.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Neur_chan_memb PF02932.16 EGG21581.1 - 0.2 11.7 2.1 0.42 10.6 2.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ATP-synt_E PF05680.12 EGG21581.1 - 1.8 9.0 7.2 0.17 12.2 2.3 1.8 2 0 0 2 2 1 0 ATP synthase E chain PPR PF01535.20 EGG21582.1 - 0.014 15.6 0.1 0.062 13.6 0.1 2.2 1 0 0 1 1 1 0 PPR repeat HEAT_UF PF18817.1 EGG21582.1 - 0.037 14.3 0.1 1.3 9.4 0.0 2.7 2 0 0 2 2 2 0 Repeat of uncharacterized protein PH0542 FXR_C1 PF16096.5 EGG21583.1 - 0.97 9.7 6.1 1.7 8.9 0.4 2.8 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Kinesin PF00225.23 EGG21584.1 - 7.7e-58 196.0 0.7 7.7e-58 196.0 0.7 3.9 4 2 1 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 EGG21584.1 - 3.6e-12 46.5 3.9 6.6e-12 45.6 0.0 3.0 2 0 0 2 2 2 1 Microtubule binding Rx_N PF18052.1 EGG21584.1 - 0.0033 17.7 2.3 0.0033 17.7 2.3 3.1 3 0 0 3 3 3 1 Rx N-terminal domain zf-ISL3 PF14690.6 EGG21584.1 - 0.14 12.8 0.1 0.35 11.6 0.1 1.6 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 POTRA_TamA_1 PF17243.2 EGG21584.1 - 6.5 6.9 7.3 5.3 7.2 2.9 2.9 2 0 0 2 2 2 0 POTRA domain TamA domain 1 DUF810 PF05664.11 EGG21585.1 - 6.6e-19 67.9 9.2 7.9e-18 64.4 9.2 2.1 1 1 0 1 1 1 1 Plant family of unknown function (DUF810) DUSP PF06337.12 EGG21586.1 - 3.7e-08 33.9 1.4 7.7e-08 32.9 0.4 2.0 2 1 0 2 2 2 1 DUSP domain Filamin PF00630.19 EGG21588.1 - 1.2e-125 411.5 12.0 3.3e-22 79.2 0.1 6.1 6 0 0 6 6 6 6 Filamin/ABP280 repeat CH PF00307.31 EGG21588.1 - 4.1e-43 146.0 0.2 5e-22 78.1 0.4 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain Invasin_D3 PF09134.10 EGG21588.1 - 2.2e-31 108.0 15.6 6.7e-05 23.1 0.8 6.3 6 0 0 6 6 6 6 Invasin, domain 3 YtkA PF13115.6 EGG21588.1 - 3.7e-09 37.1 19.3 0.25 12.0 0.5 6.7 5 1 2 7 7 7 4 YtkA-like Y_Y_Y PF07495.13 EGG21588.1 - 5.9e-08 32.5 6.9 0.0082 16.1 0.1 6.7 8 0 0 8 8 8 1 Y_Y_Y domain DUF5060 PF16586.5 EGG21588.1 - 1.7e-07 31.5 0.8 8 6.9 0.0 5.8 5 0 0 5 5 5 1 Domain of unknown function (DUF5060) CAMSAP_CH PF11971.8 EGG21588.1 - 1.7e-06 27.7 0.0 0.072 12.9 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain CopC PF04234.12 EGG21588.1 - 6.4e-05 23.9 4.5 11 7.1 0.1 5.7 6 0 0 6 6 6 0 CopC domain Big_6 PF17936.1 EGG21588.1 - 0.00073 19.8 20.0 2.1 8.7 0.0 8.0 8 2 1 9 9 8 2 Bacterial Ig domain Neurexophilin PF06312.12 EGG21588.1 - 0.00088 18.8 0.1 7.5 5.9 0.0 4.8 5 0 0 5 5 5 1 Neurexophilin Big_1 PF02369.16 EGG21588.1 - 0.00089 19.2 13.0 5.3 7.1 0.1 6.6 5 1 2 7 7 7 2 Bacterial Ig-like domain (group 1) Glyco_hydro2_C5 PF18565.1 EGG21588.1 - 0.0015 18.3 5.8 1.8 8.5 0.1 4.1 4 0 0 4 4 4 1 Glycoside hydrolase family 2 C-terminal domain 5 LEA_2 PF03168.13 EGG21588.1 - 0.031 14.8 0.2 3 8.4 0.1 2.9 2 0 0 2 2 2 0 Late embryogenesis abundant protein PKD PF00801.20 EGG21588.1 - 0.14 12.0 7.1 5.4 6.9 0.0 5.1 7 0 0 7 7 6 0 PKD domain Big_3_5 PF16640.5 EGG21588.1 - 0.3 11.3 18.5 4.7 7.5 1.5 5.6 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 3) Cadherin_5 PF17892.1 EGG21588.1 - 1 9.4 17.3 3.3 7.7 0.0 6.0 6 0 0 6 6 6 0 Cadherin-like domain DGCR6 PF07324.11 EGG21589.1 - 5.2e-09 36.0 7.5 5.2e-09 36.0 7.5 2.8 3 0 0 3 3 3 1 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.9 EGG21589.1 - 0.0051 16.5 5.6 0.0051 16.5 5.6 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2458) DUF3040 PF11239.8 EGG21589.1 - 0.078 13.3 0.4 0.22 11.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Glucokinase PF02685.16 EGG21590.1 - 2.7e-22 79.2 0.0 3.3e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 EGG21590.1 - 0.011 15.2 1.5 0.92 8.9 0.4 2.8 2 1 0 2 2 2 0 ROK family Hydant_A_N PF05378.13 EGG21590.1 - 0.034 13.9 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region SRF-TF PF00319.18 EGG21593.1 - 2.5e-21 74.9 0.1 3.8e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) TFIIA PF03153.13 EGG21593.1 - 7.9e-07 29.4 32.7 8.9e-07 29.2 32.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 EGG21593.1 - 0.00066 19.3 17.1 0.00087 18.9 17.1 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit TERB2 PF15101.6 EGG21593.1 - 0.0024 18.0 24.2 0.0073 16.4 24.2 1.9 1 1 0 1 1 1 1 Telomere-associated protein TERB2 DUF935 PF06074.12 EGG21593.1 - 0.014 14.2 17.9 0.018 13.8 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) eIF-3_zeta PF05091.12 EGG21593.1 - 0.023 13.7 15.6 0.028 13.4 15.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.17 EGG21593.1 - 0.032 14.4 12.0 0.048 13.8 12.0 1.3 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.9 EGG21593.1 - 0.06 11.6 33.7 0.077 11.3 33.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Paramyxo_ncap PF00973.19 EGG21593.1 - 0.063 12.2 15.4 0.08 11.9 15.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SprA-related PF12118.8 EGG21593.1 - 0.067 12.3 30.8 0.11 11.6 30.8 1.3 1 0 0 1 1 1 0 SprA-related family Lin-8 PF03353.15 EGG21593.1 - 0.14 11.7 21.2 0.2 11.2 21.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spore_coat_CotO PF14153.6 EGG21593.1 - 0.15 12.0 23.2 0.24 11.3 23.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DUF1682 PF07946.14 EGG21593.1 - 0.24 10.6 7.6 0.31 10.2 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) EIF4E-T PF10477.9 EGG21593.1 - 0.25 10.1 23.0 0.38 9.5 23.0 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E LAP1C PF05609.12 EGG21593.1 - 0.43 9.6 19.6 0.61 9.1 19.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4407 PF14362.6 EGG21593.1 - 0.49 9.7 19.1 0.78 9.0 19.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SLC12 PF03522.15 EGG21593.1 - 0.5 9.3 17.4 0.65 9.0 17.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 EGG21593.1 - 0.52 8.5 12.9 0.73 8.0 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein HemX PF04375.14 EGG21593.1 - 0.55 9.5 31.3 0.78 9.0 31.3 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CDK5_activator PF03261.15 EGG21593.1 - 0.77 9.2 13.4 0.95 8.9 13.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Hamartin PF04388.12 EGG21593.1 - 0.82 8.3 23.6 1.1 7.9 23.6 1.1 1 0 0 1 1 1 0 Hamartin protein SID-1_RNA_chan PF13965.6 EGG21593.1 - 0.84 8.0 5.8 1.1 7.6 5.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Raftlin PF15250.6 EGG21593.1 - 0.86 8.3 16.3 1.2 7.8 16.3 1.2 1 0 0 1 1 1 0 Raftlin DUF4192 PF13830.6 EGG21593.1 - 1.1 9.2 9.8 1.5 8.8 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Zip PF02535.22 EGG21593.1 - 1.1 8.4 8.2 1.7 7.8 8.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Sin_N PF04801.13 EGG21593.1 - 1.5 7.9 26.6 2 7.6 26.6 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Bud13 PF09736.9 EGG21593.1 - 1.7 9.0 20.3 3 8.2 20.3 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex NARP1 PF12569.8 EGG21593.1 - 1.7 7.4 18.0 2.5 6.9 18.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 EGG21593.1 - 1.8 7.2 25.1 2.4 6.8 25.1 1.1 1 0 0 1 1 1 0 Presenilin XRN_M PF17846.1 EGG21593.1 - 1.9 7.4 9.6 2.3 7.1 9.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain STAC2_u1 PF16664.5 EGG21593.1 - 1.9 8.9 20.7 2.8 8.4 16.0 2.4 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 MMR1 PF08505.10 EGG21593.1 - 1.9 8.7 24.5 3 8.1 24.5 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF1387 PF07139.11 EGG21593.1 - 2.1 8.0 20.4 3.5 7.3 20.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Asp-B-Hydro_N PF05279.11 EGG21593.1 - 2.4 8.1 11.7 3.6 7.6 11.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region BPL_N PF09825.9 EGG21593.1 - 2.6 7.0 12.6 3.7 6.5 12.6 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Nop53 PF07767.11 EGG21593.1 - 2.8 7.3 22.3 4 6.7 22.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2126 PF09899.9 EGG21593.1 - 2.9 5.9 12.7 3.7 5.5 12.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2052 PF09747.9 EGG21593.1 - 2.9 8.0 18.2 4.5 7.4 18.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 EGG21593.1 - 3 7.6 22.4 5.1 6.8 22.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nucleo_P87 PF07267.11 EGG21593.1 - 3.4 6.4 17.4 4.8 5.9 17.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Dicty_REP PF05086.12 EGG21593.1 - 4.2 5.2 12.8 4.9 5.0 12.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3584 PF12128.8 EGG21593.1 - 4.4 4.7 28.2 6 4.2 28.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ctr PF04145.15 EGG21593.1 - 4.9 7.8 11.3 9.4 6.8 11.3 1.6 1 0 0 1 1 1 0 Ctr copper transporter family Plasmodium_Vir PF05795.11 EGG21593.1 - 5.4 6.3 8.7 8 5.8 8.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein HAUS6_N PF14661.6 EGG21593.1 - 5.8 6.4 20.2 8.3 5.9 20.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FAM222A PF15258.6 EGG21593.1 - 6.2 5.8 41.5 9.2 5.2 41.5 1.2 1 0 0 1 1 1 0 Protein family of FAM222A DUF2828 PF11443.8 EGG21593.1 - 6.8 4.7 18.2 9.3 4.2 18.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RIFIN PF02009.16 EGG21593.1 - 8.1 6.2 17.3 11 5.8 17.3 1.2 1 0 0 1 1 1 0 Rifin PRC2_HTH_1 PF18118.1 EGG21593.1 - 8.3 7.3 12.6 18 6.2 12.6 1.6 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain LMBR1 PF04791.16 EGG21593.1 - 8.5 5.2 10.9 10 4.9 10.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Membralin PF09746.9 EGG21593.1 - 8.7 5.3 12.8 14 4.6 12.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein ALMT PF11744.8 EGG21593.1 - 9.2 5.0 17.6 13 4.5 17.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Gti1_Pac2 PF09729.9 EGG21593.1 - 9.6 6.2 17.6 7.2 6.7 14.8 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Borrelia_P83 PF05262.11 EGG21593.1 - 9.8 4.5 20.3 13 4.1 20.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Branch PF02485.21 EGG21594.1 - 6.9e-11 42.1 4.6 2.4e-08 33.8 1.1 2.3 2 0 0 2 2 2 2 Core-2/I-Branching enzyme hEGF PF12661.7 EGG21594.1 - 0.052 14.2 2.4 0.11 13.2 2.4 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 EGG21594.1 - 0.41 10.8 2.2 1.1 9.4 2.2 1.7 1 0 0 1 1 1 0 Tenascin EGF domain PNTB PF02233.16 EGG21595.1 - 4.5e-173 576.4 21.3 4.5e-173 576.4 21.3 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EGG21595.1 - 4.7e-73 245.0 0.3 9.4e-73 244.0 0.3 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EGG21595.1 - 4.4e-42 143.6 0.1 1.3e-41 142.1 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EGG21595.1 - 7.8e-33 112.8 4.9 7.8e-33 112.8 4.9 5.0 4 1 1 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EGG21595.1 - 5.9e-06 25.8 1.0 0.19 11.1 0.1 3.3 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DSPc PF00782.20 EGG21596.1 - 7.2e-28 97.0 0.0 1.8e-27 95.8 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG21596.1 - 0.029 13.9 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PPR_2 PF13041.6 EGG21597.1 - 0.00035 20.7 5.6 0.26 11.5 0.4 4.8 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 EGG21597.1 - 0.027 14.5 7.2 0.51 10.5 0.2 4.5 3 1 3 6 6 6 0 Pentatricopeptide repeat domain PPR PF01535.20 EGG21597.1 - 0.12 12.7 0.2 5.5 7.5 0.0 3.4 3 0 0 3 3 3 0 PPR repeat ACPS PF01648.20 EGG21598.1 - 1.2e-18 67.3 0.1 7.2e-18 64.8 0.0 2.0 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily BTB PF00651.31 EGG21599.1 - 3.4e-13 49.8 0.2 1.2e-05 25.5 0.0 3.6 2 1 2 4 4 4 2 BTB/POZ domain BACK PF07707.15 EGG21599.1 - 3.6e-09 36.6 4.5 1e-07 32.0 2.4 2.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF3342 PF11822.8 EGG21599.1 - 0.11 12.7 1.1 1.5 9.1 0.1 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3342) CK_II_beta PF01214.18 EGG21600.1 - 4e-68 228.8 0.0 6.1e-67 225.0 0.0 2.0 1 1 0 1 1 1 1 Casein kinase II regulatory subunit DEAD PF00270.29 EGG21601.1 - 1.1e-42 145.8 2.2 1.1e-42 145.8 2.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG21601.1 - 3.1e-33 114.4 0.7 6.2e-32 110.2 0.2 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EGG21601.1 - 3.9e-07 30.0 0.4 9.1e-07 28.8 0.2 1.7 2 0 0 2 2 2 1 AAA domain UTP25 PF06862.12 EGG21601.1 - 0.00028 19.8 0.1 0.29 9.9 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 EGG21601.1 - 0.00077 19.5 0.0 0.002 18.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA-synt_1b PF00579.25 EGG21601.1 - 0.0014 18.0 0.0 0.0034 16.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) AAA_19 PF13245.6 EGG21601.1 - 0.0015 18.9 0.9 0.0022 18.3 0.2 1.7 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 EGG21601.1 - 0.0017 17.7 0.1 0.004 16.5 0.1 1.7 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 EGG21601.1 - 0.0072 16.6 0.3 0.019 15.2 0.3 1.7 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EGG21601.1 - 0.0081 16.0 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Helicase TniB PF05621.11 EGG21601.1 - 0.039 13.4 0.0 0.09 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein SWI2_SNF2 PF18766.1 EGG21601.1 - 0.076 12.7 0.3 0.15 11.7 0.2 1.6 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Xan_ur_permease PF00860.20 EGG21602.1 - 6.4e-79 265.4 45.0 7.7e-79 265.2 45.0 1.1 1 0 0 1 1 1 1 Permease family Xan_ur_permease PF00860.20 EGG21603.1 - 1.8e-79 267.2 43.1 2.2e-79 267.0 43.1 1.1 1 0 0 1 1 1 1 Permease family Usher_TcfC PF17271.2 EGG21603.1 - 0.087 11.6 0.2 0.12 11.1 0.2 1.1 1 0 0 1 1 1 0 TcfC Usher-like barrel domain Xan_ur_permease PF00860.20 EGG21604.1 - 1.4e-78 264.3 40.6 1.8e-78 264.0 40.6 1.1 1 0 0 1 1 1 1 Permease family EB PF01683.18 EGG21605.1 - 0.00022 21.5 2.0 0.00051 20.3 2.0 1.6 1 0 0 1 1 1 1 EB module LRR_8 PF13855.6 EGG21605.1 - 0.00086 19.0 1.3 7.3 6.4 0.0 4.4 3 0 0 3 3 3 1 Leucine rich repeat EGF_2 PF07974.13 EGG21605.1 - 0.0015 18.9 13.3 0.0037 17.6 13.3 1.7 1 0 0 1 1 1 1 EGF-like domain DUF3844 PF12955.7 EGG21605.1 - 0.013 15.6 0.2 0.043 14.0 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) EGF_Tenascin PF18720.1 EGG21605.1 - 0.013 15.5 7.9 0.044 13.8 7.9 1.9 1 0 0 1 1 1 0 Tenascin EGF domain hEGF PF12661.7 EGG21605.1 - 0.013 16.1 9.3 0.038 14.6 9.3 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF LRR_4 PF12799.7 EGG21605.1 - 0.023 15.1 12.8 0.72 10.4 0.6 6.3 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) EGF PF00008.27 EGG21605.1 - 0.055 13.8 9.2 0.15 12.4 9.2 1.8 1 0 0 1 1 1 0 EGF-like domain I-EGF_1 PF18372.1 EGG21605.1 - 0.58 10.3 9.7 1.2 9.3 9.7 1.5 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 LRR_1 PF00560.33 EGG21605.1 - 1.7 9.5 5.3 45 5.2 0.1 5.2 4 0 0 4 4 4 0 Leucine Rich Repeat Toxin_2 PF00451.19 EGG21605.1 - 3.9 7.8 8.5 8 6.9 8.5 1.5 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 Syja_N PF02383.18 EGG21606.1 - 1.8e-78 264.1 0.0 3e-78 263.4 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain DUF3430 PF11912.8 EGG21606.1 - 4.4e-14 53.0 20.5 4.4e-14 53.0 20.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGG21606.1 - 5.3 7.3 8.3 8.6 6.7 2.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3586) SET PF00856.28 EGG21608.1 - 0.0082 16.5 0.0 2.9 8.3 0.0 2.5 1 1 1 2 2 2 2 SET domain Me-amine-dh_H PF06433.11 EGG21608.1 - 0.097 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) Anti-TRAP PF15777.5 EGG21608.1 - 1.1 9.2 7.2 6 6.9 1.1 2.7 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cellulose_synt PF03552.14 EGG21610.1 - 3.3e-23 82.1 11.5 4.9e-13 48.5 2.9 4.2 3 1 1 4 4 4 4 Cellulose synthase Glyco_trans_2_3 PF13632.6 EGG21610.1 - 6.8e-22 78.4 0.1 6.8e-22 78.4 0.1 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGG21610.1 - 2.5e-14 53.7 0.0 2e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGG21610.1 - 1.7e-09 37.7 0.0 1.7e-08 34.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGG21610.1 - 4.4e-06 26.3 0.0 7.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 HXXEE PF13787.6 EGG21610.1 - 0.86 10.4 11.1 1.2 9.9 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function with HXXEE motif DUF4407 PF14362.6 EGG21611.1 - 1.4 8.2 7.8 2.7 7.3 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 EGG21612.1 - 3.4e-57 190.2 2.0 3.4e-19 68.4 0.2 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG21612.1 - 4.7e-10 39.1 1.8 0.017 14.7 0.2 3.5 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG21612.1 - 1e-06 28.7 1.6 0.0083 16.2 0.0 4.3 3 1 0 3 3 3 1 RNA recognition motif RNA_bind PF08675.11 EGG21612.1 - 0.00032 20.6 0.0 1.7 8.7 0.0 3.7 3 1 0 3 3 3 1 RNA binding domain TFIIA PF03153.13 EGG21612.1 - 0.0038 17.3 21.8 0.0047 17.0 21.8 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RRM_occluded PF16842.5 EGG21612.1 - 0.022 14.6 0.0 4.2 7.3 0.0 3.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGG21612.1 - 0.067 13.2 0.4 22 5.1 0.0 3.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGG21612.1 - 0.095 12.7 19.4 0.25 11.4 0.3 4.5 3 1 2 5 5 5 0 RNA binding motif RRM_Rrp7 PF17799.1 EGG21612.1 - 0.1 12.4 3.8 0.39 10.5 0.0 3.1 3 1 0 3 3 3 0 Rrp7 RRM-like N-terminal domain SARAF PF06682.12 EGG21612.1 - 0.14 11.8 11.8 0.21 11.2 11.8 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Neur_chan_memb PF02932.16 EGG21612.1 - 4.4 7.3 7.2 7.7 6.5 7.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM70 PF14967.6 EGG21612.1 - 6.3 6.2 5.5 9.5 5.6 5.0 1.5 2 0 0 2 2 2 0 FAM70 protein Presenilin PF01080.17 EGG21612.1 - 7.4 5.2 9.8 11 4.7 9.8 1.2 1 0 0 1 1 1 0 Presenilin DSPc PF00782.20 EGG21613.1 - 1.4e-20 73.4 10.1 5.1e-15 55.5 0.0 4.2 4 0 0 4 4 4 3 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGG21613.1 - 3.8e-08 33.6 1.2 3.8e-08 33.6 1.2 3.8 3 1 1 4 4 4 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 EGG21613.1 - 0.021 15.1 0.0 0.076 13.3 0.0 2.1 1 0 0 1 1 1 0 Rit1 DUSP-like domain V-SNARE PF05008.15 EGG21614.1 - 3.3e-13 49.8 4.2 3.3e-13 49.8 4.2 2.8 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EGG21614.1 - 7.3e-10 39.0 3.6 7.3e-10 39.0 3.6 2.6 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EGG21614.1 - 1.5e-05 24.8 0.4 1.5e-05 24.8 0.4 2.4 3 0 0 3 3 3 1 Sec20 CALCOCO1 PF07888.11 EGG21614.1 - 0.00026 20.0 5.1 0.00033 19.7 5.1 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4407 PF14362.6 EGG21614.1 - 0.00074 19.0 2.9 0.00096 18.6 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Cytochrom_B562 PF07361.11 EGG21614.1 - 0.0024 18.5 1.7 0.0024 18.5 1.7 2.1 2 1 0 2 2 2 1 Cytochrome b562 LMBR1 PF04791.16 EGG21614.1 - 0.022 13.7 2.8 0.028 13.4 2.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MscS_porin PF12795.7 EGG21614.1 - 0.066 12.8 9.5 0.1 12.1 9.5 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Rootletin PF15035.6 EGG21614.1 - 0.14 12.2 8.1 0.086 12.9 4.9 1.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Laminin_II PF06009.12 EGG21614.1 - 0.15 12.0 6.4 0.46 10.5 0.6 2.4 2 1 0 2 2 2 0 Laminin Domain II DUF2175 PF09943.9 EGG21614.1 - 0.26 11.6 3.9 0.13 12.6 1.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) BST2 PF16716.5 EGG21614.1 - 0.27 11.9 7.4 3.3 8.4 1.6 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 LRRC37AB_C PF14914.6 EGG21614.1 - 1.7 8.5 9.1 0.48 10.3 0.8 2.5 1 1 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Cnn_1N PF07989.11 EGG21614.1 - 2 8.6 5.6 1.5 9.0 1.6 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Uso1_p115_C PF04871.13 EGG21614.1 - 3.1 8.2 10.2 7.4 7.0 6.7 2.3 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Syntaxin_2 PF14523.6 EGG21614.1 - 6.4 7.2 12.0 3.8 7.9 3.6 3.1 3 1 0 3 3 3 0 Syntaxin-like protein OmpH PF03938.14 EGG21614.1 - 6.5 7.1 15.6 58 4.0 15.7 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Helicase_C PF00271.31 EGG21615.1 - 1.8e-18 66.9 0.1 5.3e-18 65.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HRDC PF00570.23 EGG21615.1 - 6.3e-15 54.9 0.0 1.3e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 HRDC domain RQC PF09382.10 EGG21615.1 - 2.1e-14 53.3 0.3 1.9e-13 50.2 0.1 2.2 2 0 0 2 2 2 1 RQC domain DEAD PF00270.29 EGG21615.1 - 5e-14 52.4 0.0 4.8e-13 49.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EGG21615.1 - 2.9e-06 27.9 0.1 2.9e-06 27.9 0.1 3.7 4 0 0 4 4 4 1 RecQ zinc-binding DEAD PF00270.29 EGG21616.1 - 5.5e-42 143.5 0.4 1.3e-41 142.3 0.4 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG21616.1 - 1.9e-27 95.8 2.1 8.8e-27 93.6 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG21616.1 - 3.2e-05 24.0 0.0 5.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGG21616.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 EGG21616.1 - 0.028 14.8 0.4 0.08 13.3 0.3 1.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGG21616.1 - 0.068 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGG21616.1 - 0.11 12.8 0.4 1 9.6 0.4 2.4 1 1 0 1 1 1 0 AAA domain Fanconi_A PF03511.14 EGG21616.1 - 0.11 12.4 0.1 0.54 10.2 0.1 2.0 2 0 0 2 2 2 0 Fanconi anaemia group A protein tRNA-synt_1b PF00579.25 EGG21616.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) AATF-Che1 PF13339.6 EGG21617.1 - 1.2e-25 90.8 4.5 1.2e-25 90.8 4.5 3.9 4 1 0 4 4 4 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 EGG21617.1 - 1.6e-14 54.2 0.9 1.6e-14 54.2 0.9 3.6 5 1 0 5 5 5 1 Apoptosis-antagonizing transcription factor, C-terminal HeLo PF14479.6 EGG21617.1 - 0.23 11.3 7.5 0.19 11.5 4.1 2.5 1 1 1 2 2 2 0 Prion-inhibition and propagation AAA PF00004.29 EGG21618.1 - 6e-45 152.9 0.1 1.7e-44 151.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG21618.1 - 5.7e-11 42.0 0.0 2.2e-10 40.2 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGG21618.1 - 8.8e-09 35.5 0.1 2.4e-08 34.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 EGG21618.1 - 1.3e-08 34.7 0.1 4e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EGG21618.1 - 1.5e-07 31.9 0.3 4.8e-05 23.8 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 EGG21618.1 - 2.4e-07 31.0 0.0 4.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGG21618.1 - 2.4e-05 24.6 1.4 0.0067 16.7 0.1 3.1 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 EGG21618.1 - 6.3e-05 22.8 0.0 0.00022 21.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EGG21618.1 - 9.2e-05 21.7 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EGG21618.1 - 0.00033 21.2 0.0 0.001 19.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EGG21618.1 - 0.00071 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 EGG21618.1 - 0.00072 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGG21618.1 - 0.0014 19.0 0.0 0.004 17.5 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 EGG21618.1 - 0.0014 18.1 0.0 0.0035 16.8 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGG21618.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 EGG21618.1 - 0.0016 18.2 0.1 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 EGG21618.1 - 0.002 18.1 0.0 0.0094 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EGG21618.1 - 0.0042 17.1 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGG21618.1 - 0.0053 16.3 0.1 0.041 13.4 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 EGG21618.1 - 0.0064 16.4 0.0 0.096 12.6 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_25 PF13481.6 EGG21618.1 - 0.009 15.6 0.6 0.035 13.7 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EGG21618.1 - 0.0097 16.1 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGG21618.1 - 0.011 15.5 0.1 0.027 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EGG21618.1 - 0.012 15.6 0.1 0.069 13.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 EGG21618.1 - 0.014 15.3 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGG21618.1 - 0.017 14.9 0.1 0.036 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EGG21618.1 - 0.02 14.3 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Parvo_NS1 PF01057.17 EGG21618.1 - 0.021 13.9 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 EGG21618.1 - 0.048 12.8 0.6 0.4 9.8 0.0 2.4 3 0 0 3 3 2 0 NB-ARC domain ABC_tran PF00005.27 EGG21618.1 - 0.057 13.9 0.4 0.75 10.3 0.0 3.0 3 1 0 3 3 3 0 ABC transporter ATPase PF06745.13 EGG21618.1 - 0.058 12.7 0.5 0.47 9.7 0.0 2.4 3 0 0 3 3 3 0 KaiC Rab5ip PF07019.12 EGG21619.1 - 4.4e-12 46.4 2.9 8.1e-12 45.6 2.9 1.4 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Serinc PF03348.15 EGG21619.1 - 1.2 8.0 6.5 2.5 6.9 6.5 1.5 1 1 0 1 1 1 0 Serine incorporator (Serinc) PPIP5K2_N PF18086.1 EGG21620.1 - 4.8e-26 90.7 1.4 4.2e-24 84.5 1.6 2.6 2 1 0 2 2 2 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EGG21620.1 - 5.6e-10 39.1 0.0 3.7e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 RimK-like ATP-grasp domain WD40 PF00400.32 EGG21623.1 - 1.7e-30 104.6 13.2 3.8e-08 33.8 0.1 10.1 9 0 0 9 9 9 4 WD domain, G-beta repeat Utp12 PF04003.12 EGG21623.1 - 1.8e-22 79.7 0.0 4.8e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Dip2/Utp12 Family Bromodomain PF00439.25 EGG21623.1 - 3e-20 72.1 0.4 1.2e-19 70.1 0.0 2.3 2 0 0 2 2 2 1 Bromodomain ANAPC4_WD40 PF12894.7 EGG21623.1 - 8.2e-18 64.5 0.0 0.34 11.2 0.0 7.6 3 3 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Acetyltransf_1 PF00583.25 EGG21623.1 - 3.4e-07 30.5 0.0 3.4e-07 30.5 0.0 2.3 2 0 0 2 2 1 1 Acetyltransferase (GNAT) family PD40 PF07676.12 EGG21623.1 - 1.6e-06 27.9 0.7 7.9 6.5 0.0 6.4 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EGG21623.1 - 1.2e-05 24.5 1.6 0.03 13.3 0.0 4.4 2 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SDA1 PF05285.12 EGG21623.1 - 2.8e-05 23.7 36.4 0.00014 21.4 21.2 2.2 2 0 0 2 2 2 2 SDA1 WD40_like PF17005.5 EGG21623.1 - 3.6e-05 23.2 1.0 0.0064 15.9 0.1 3.8 2 1 0 2 2 2 1 WD40-like domain Nop14 PF04147.12 EGG21623.1 - 0.0009 17.6 25.5 0.0009 17.6 25.5 2.6 2 1 0 2 2 1 1 Nop14-like family Acetyltransf_7 PF13508.7 EGG21623.1 - 0.00097 19.5 0.2 0.0023 18.3 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CDC45 PF02724.14 EGG21623.1 - 0.014 13.7 42.4 0.17 10.1 23.5 2.6 3 0 0 3 3 3 0 CDC45-like protein Baculo_11_kDa PF06143.11 EGG21623.1 - 0.035 13.7 0.3 0.12 12.0 0.3 1.9 1 0 0 1 1 1 0 Baculovirus 11 kDa family YL1 PF05764.13 EGG21623.1 - 0.36 10.9 41.6 0.3 11.2 25.0 2.5 2 0 0 2 2 2 0 YL1 nuclear protein NHL PF01436.21 EGG21623.1 - 0.36 11.0 2.3 78 3.6 0.1 4.2 4 0 0 4 4 4 0 NHL repeat DUF840 PF05801.11 EGG21623.1 - 0.51 10.4 1.9 4.5 7.4 0.0 2.9 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) DUF3395 PF11875.8 EGG21624.1 - 6.4e-42 143.1 0.4 1.1e-41 142.3 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EGG21624.1 - 1.6e-18 66.6 0.5 4.1e-18 65.3 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain DUF1797 PF08796.10 EGG21624.1 - 0.042 13.9 0.1 0.042 13.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) Pyrophosphatase PF00719.19 EGG21625.1 - 1.9e-50 170.8 0.7 2.4e-50 170.5 0.7 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase eIF2A PF08662.11 EGG21626.1 - 3.3e-63 213.1 0.1 1.5e-60 204.4 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Y_phosphatase2 PF03162.13 EGG21627.1 - 3.9e-43 146.9 0.0 7.8e-43 145.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGG21627.1 - 0.0038 16.8 0.0 0.0074 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGG21627.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family RabGAP-TBC PF00566.18 EGG21628.1 - 1.2e-16 61.0 1.2 2.9e-16 59.8 1.2 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain zf-B_box PF00643.24 EGG21628.1 - 0.00078 19.6 4.4 0.00078 19.6 4.4 2.6 2 1 0 2 2 2 1 B-box zinc finger zf-C3HC4_4 PF15227.6 EGG21628.1 - 0.049 13.8 3.8 0.14 12.3 3.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGG21628.1 - 0.068 13.0 4.5 0.16 11.8 4.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2318 PF10080.9 EGG21628.1 - 0.14 12.3 1.9 0.3 11.2 1.9 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) YqzE PF14038.6 EGG21628.1 - 0.35 10.9 1.6 1.1 9.4 1.6 1.8 1 0 0 1 1 1 0 YqzE-like protein Glyco_hydro_25 PF01183.20 EGG21629.1 - 3e-05 24.3 0.0 4.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 BTB PF00651.31 EGG21630.1 - 1.5e-17 63.9 2.6 5e-15 55.7 0.6 3.2 2 1 1 3 3 3 1 BTB/POZ domain RCC1 PF00415.18 EGG21630.1 - 5.3e-13 49.4 0.0 3.9e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG21630.1 - 3.5e-10 39.4 2.5 1.5e-08 34.2 2.3 2.5 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat BACK PF07707.15 EGG21630.1 - 0.053 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 BTB And C-terminal Kelch Tmemb_185A PF10269.9 EGG21631.1 - 0.3 10.7 5.2 0.19 11.4 3.2 1.7 1 1 0 1 1 1 0 Transmembrane Fragile-X-F protein DUF1216 PF06746.11 EGG21631.1 - 1.2 9.2 0.0 1.2 9.2 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1216) TFCD_C PF12612.8 EGG21632.1 - 3.8e-24 85.6 3.3 2.6e-23 82.9 0.0 3.8 4 1 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EGG21632.1 - 0.00086 19.4 2.5 50 4.5 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat ATP-synt_8 PF00895.20 EGG21632.1 - 0.12 12.9 3.6 0.12 12.8 0.0 3.0 3 0 0 3 3 3 0 ATP synthase protein 8 RRM_1 PF00076.22 EGG21634.1 - 1.3e-17 63.3 0.1 2.4e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 EGG21634.1 - 9.8e-16 58.2 6.2 9.8e-16 58.2 6.2 3.0 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Med3 PF11593.8 EGG21634.1 - 0.077 12.2 19.4 0.14 11.4 19.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RNA_pol_Rpb4 PF03874.16 EGG21635.1 - 1.2e-21 77.2 3.0 2.2e-21 76.4 3.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb4 Voltage_CLC PF00654.20 EGG21636.1 - 6.4e-96 321.7 20.7 6.4e-96 321.7 20.7 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 EGG21636.1 - 1.5e-12 47.7 0.1 5.4e-05 23.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain Tfb2 PF03849.14 EGG21637.1 - 1.1e-117 393.1 5.4 1.2e-117 392.8 5.4 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EGG21637.1 - 1.6e-23 82.9 0.2 4.2e-23 81.5 0.2 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain DUF5100 PF17029.5 EGG21637.1 - 0.087 12.7 0.2 0.19 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) Helicase_C_3 PF13625.6 EGG21637.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain GST_C_2 PF13410.6 EGG21638.1 - 0.016 15.2 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain AAA_22 PF13401.6 EGG21638.1 - 0.09 13.0 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 EGG21640.1 - 4.9e-65 219.5 0.0 1.6e-64 217.8 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21640.1 - 9.8e-47 159.4 0.0 2.2e-46 158.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EGG21640.1 - 4.2e-09 36.6 0.3 3e-08 33.9 0.3 2.6 1 0 0 1 1 1 1 P21-Rho-binding domain C1_1 PF00130.22 EGG21640.1 - 5.9e-08 32.5 11.4 1e-07 31.7 11.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SBF2 PF12335.8 EGG21640.1 - 7e-08 32.4 0.5 7e-08 32.4 0.5 2.6 3 0 0 3 3 2 1 Myotubularin protein CH PF00307.31 EGG21640.1 - 2e-06 28.0 0.0 2e-06 28.0 0.0 3.1 3 0 0 3 3 3 1 Calponin homology (CH) domain Pkinase_fungal PF17667.1 EGG21640.1 - 0.0005 19.0 0.5 0.001 17.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase DUF4201 PF13870.6 EGG21640.1 - 0.0074 16.0 0.9 0.0074 16.0 0.9 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Staphostatin_B PF09023.10 EGG21640.1 - 0.012 15.7 1.1 5.1 7.2 0.2 2.9 2 0 0 2 2 2 0 Staphostatin B C1_2 PF03107.16 EGG21640.1 - 0.12 12.7 3.1 0.32 11.3 3.1 1.8 1 0 0 1 1 1 0 C1 domain FliJ PF02050.16 EGG21640.1 - 3.5 7.9 8.1 17 5.6 0.2 2.8 2 0 0 2 2 2 0 Flagellar FliJ protein DUF724 PF05266.14 EGG21640.1 - 4.4 7.1 7.8 0.76 9.6 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4763 PF15960.5 EGG21640.1 - 9.3 5.5 14.1 3.1 7.1 9.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) UCH_1 PF13423.6 EGG21641.1 - 1.4e-80 271.3 16.7 2.5e-80 270.5 16.7 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EGG21641.1 - 2.1e-20 73.9 0.0 6.2e-20 72.4 0.0 1.9 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 EGG21641.1 - 4.3e-09 36.2 7.6 2.4e-08 33.8 8.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Zip PF02535.22 EGG21641.1 - 1.6 7.9 4.2 2.6 7.2 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Dus PF01207.17 EGG21642.1 - 7e-68 229.0 0.0 1.3e-67 228.1 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EGG21642.1 - 0.012 14.9 0.0 0.039 13.2 0.0 1.9 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase DUF2274 PF10038.9 EGG21642.1 - 0.074 13.5 0.0 0.27 11.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) NMO PF03060.15 EGG21642.1 - 0.078 12.3 0.1 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase His_biosynth PF00977.21 EGG21642.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein G3P_antiterm PF04309.12 EGG21642.1 - 0.11 11.9 0.0 0.4 10.1 0.0 1.9 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Glyco_hydro_35 PF01301.19 EGG21643.1 - 6.9e-106 354.4 3.1 9.7e-106 354.0 3.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 EGG21643.1 - 7.6e-10 38.7 5.1 2.3e-09 37.1 4.7 2.0 1 1 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.18 EGG21643.1 - 7.5e-06 25.6 0.2 1.3e-05 24.8 0.2 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GHD PF17834.1 EGG21643.1 - 5.3e-05 23.2 0.4 0.00011 22.2 0.4 1.5 1 0 0 1 1 1 1 Beta-sandwich domain in beta galactosidase BetaGal_dom4_5 PF13364.6 EGG21643.1 - 0.00052 20.6 3.1 1.4 9.5 0.0 3.3 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain RhoGEF PF00621.20 EGG21644.1 - 1.9e-35 122.7 5.0 1.9e-35 122.7 5.0 2.1 2 0 0 2 2 2 1 RhoGEF domain Cpn10 PF00166.21 EGG21645.1 - 3.1e-18 65.6 0.0 3.9e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF973 PF06157.11 EGG21645.1 - 0.025 13.6 0.1 0.031 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Cupin_2 PF07883.11 EGG21645.1 - 0.045 13.5 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Cupin domain Brix PF04427.18 EGG21646.1 - 6.2e-36 124.3 0.3 6.2e-36 124.3 0.3 1.8 2 0 0 2 2 2 1 Brix domain Ndc1_Nup PF09531.10 EGG21646.1 - 0.22 10.1 5.0 0.27 9.9 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dicty_REP PF05086.12 EGG21646.1 - 0.48 8.3 17.5 0.65 7.9 17.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein eIF-3c_N PF05470.12 EGG21646.1 - 0.89 7.8 16.3 1.7 6.8 16.3 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 EGG21646.1 - 2.2 6.5 11.7 2.7 6.2 11.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Shisa PF13908.6 EGG21646.1 - 2.2 8.5 6.5 3.7 7.8 6.5 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PTPRCAP PF15713.5 EGG21646.1 - 2.5 8.4 11.5 5.7 7.2 11.5 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FoP_duplication PF13865.6 EGG21646.1 - 4.5 7.9 9.0 1 10.0 4.6 2.1 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 CBS PF00571.28 EGG21648.1 - 1.7e-21 76.4 2.8 5.8e-11 42.7 0.3 2.3 2 0 0 2 2 2 2 CBS domain PTA_PTB PF01515.19 EGG21648.1 - 0.0031 16.9 0.7 0.0044 16.4 0.7 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA PF00004.29 EGG21649.1 - 3e-38 131.2 0.0 6.4e-38 130.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 EGG21649.1 - 5e-10 39.3 2.3 1.2e-09 38.0 2.3 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 EGG21649.1 - 4.2e-08 33.1 0.0 1.5e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 EGG21649.1 - 2.3e-06 27.3 0.0 6.1e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGG21649.1 - 8e-05 22.4 0.0 0.0002 21.1 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGG21649.1 - 0.00023 21.3 0.0 0.0006 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGG21649.1 - 0.0013 18.8 0.1 0.016 15.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 EGG21649.1 - 0.0016 17.9 0.0 0.52 9.7 0.0 2.6 1 1 0 2 2 2 1 Bacterial TniB protein TIP49 PF06068.13 EGG21649.1 - 0.0031 16.8 0.0 0.0061 15.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EGG21649.1 - 0.0057 16.9 1.6 0.51 10.6 0.0 3.4 2 1 2 4 4 4 1 AAA domain TPR_7 PF13176.6 EGG21649.1 - 0.0068 16.4 0.1 0.021 14.9 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG21649.1 - 0.0073 16.6 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Mg_chelatase PF01078.21 EGG21649.1 - 0.0078 15.6 0.1 0.021 14.2 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TPR_1 PF00515.28 EGG21649.1 - 0.0091 15.8 0.3 0.022 14.6 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG21649.1 - 0.0091 16.0 0.1 0.024 14.8 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat AAA_14 PF13173.6 EGG21649.1 - 0.018 15.0 0.1 0.27 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF4368 PF14287.6 EGG21649.1 - 0.045 14.1 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) IstB_IS21 PF01695.17 EGG21649.1 - 0.048 13.4 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EGG21649.1 - 0.077 12.7 0.1 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGG21649.1 - 0.079 13.3 0.1 0.25 11.7 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain TPR_8 PF13181.6 EGG21649.1 - 0.11 12.8 0.1 0.33 11.3 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_2 PF12796.7 EGG21650.1 - 1.5e-12 47.9 9.7 0.0078 16.8 0.1 6.9 5 1 5 10 10 10 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG21650.1 - 1.3e-06 28.2 2.2 54 4.8 0.0 8.8 10 0 0 10 10 10 1 Ankyrin repeat Ank_4 PF13637.6 EGG21650.1 - 6.9e-06 26.5 6.2 4 8.1 0.0 7.9 9 1 1 10 10 10 2 Ankyrin repeats (many copies) GDC-P PF02347.16 EGG21651.1 - 1.1e-177 591.2 0.0 6.1e-168 559.1 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EGG21651.1 - 0.00092 18.3 0.1 0.0046 16.0 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Peptidase_M50 PF02163.22 EGG21652.1 - 9.4e-19 67.7 0.0 2.2e-17 63.2 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 EGG21652.1 - 0.0036 17.6 0.0 0.0065 16.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGG21652.1 - 0.0071 16.7 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Peptidase_M50B PF13398.6 EGG21652.1 - 0.03 14.0 0.2 0.097 12.3 0.2 1.9 1 0 0 1 1 1 0 Peptidase M50B-like NPCC PF08058.11 EGG21652.1 - 1.2 9.2 3.4 5.7 7.0 0.1 2.6 2 1 0 2 2 2 0 Nuclear pore complex component Glyco_hydro_30 PF02055.16 EGG21653.1 - 1.4e-39 136.1 2.3 1.7e-39 135.8 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EGG21653.1 - 6.4e-10 38.7 0.0 4.7e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EGG21653.1 - 0.0042 16.7 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 EGG21653.1 - 0.16 12.2 1.3 0.21 11.8 0.3 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_25 PF01183.20 EGG21655.1 - 2.9e-08 34.1 1.5 4.3e-08 33.5 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 MafB19-deam PF14437.6 EGG21655.1 - 0.034 13.9 0.8 2.7 7.7 0.8 2.2 1 1 0 1 1 1 0 MafB19-like deaminase zf-RING_2 PF13639.6 EGG21657.1 - 4.3e-11 43.0 8.4 7.3e-11 42.2 8.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGG21657.1 - 3.6e-08 33.6 8.6 1.2e-07 31.8 8.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGG21657.1 - 1.1e-07 31.6 7.4 1.9e-07 30.8 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGG21657.1 - 1.1e-07 31.5 5.6 2.3e-07 30.4 5.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGG21657.1 - 8.4e-06 25.7 5.3 1.8e-05 24.6 5.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG21657.1 - 3.7e-05 23.5 8.7 8.8e-05 22.3 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG21657.1 - 0.0025 17.7 5.9 0.0056 16.6 5.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGG21657.1 - 0.0032 17.3 6.0 0.0053 16.6 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGG21657.1 - 0.0037 16.8 4.2 0.0073 15.9 4.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EGG21657.1 - 0.023 14.8 5.5 0.09 12.8 5.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 EGG21657.1 - 0.031 14.4 7.3 0.065 13.4 7.3 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 EGG21657.1 - 0.05 13.5 6.8 0.12 12.3 6.8 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 EGG21657.1 - 0.19 11.6 5.7 0.43 10.5 5.7 1.7 1 0 0 1 1 1 0 PHD-finger DDE_Tnp_1_4 PF13701.6 EGG21657.1 - 0.24 9.6 4.0 0.11 10.7 0.7 1.9 2 0 0 2 2 2 0 Transposase DDE domain group 1 zf-C3H2C3 PF17122.5 EGG21657.1 - 0.25 11.4 5.3 0.59 10.2 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger zf-P11 PF03854.14 EGG21657.1 - 0.29 10.8 8.7 0.63 9.7 8.2 1.9 1 1 0 1 1 1 0 P-11 zinc finger FANCL_C PF11793.8 EGG21657.1 - 0.34 11.1 5.4 1.2 9.4 5.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 EGG21657.1 - 0.34 10.8 4.4 0.88 9.4 4.4 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 EGG21657.1 - 1.2 9.1 6.5 1.3 9.0 2.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2756 PF10956.8 EGG21657.1 - 2.4 8.7 11.3 8.5 6.9 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) DUF3836 PF12930.7 EGG21657.1 - 3.9 7.2 9.4 0.38 10.5 4.0 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF3836) Exo_endo_phos PF03372.23 EGG21658.1 - 3.9e-11 42.9 0.0 1.2e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FAA_hydrolase PF01557.18 EGG21659.1 - 1.7e-56 191.3 0.0 3.8e-56 190.2 0.0 1.6 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DEAD PF00270.29 EGG21659.1 - 1e-41 142.6 0.1 2.2e-41 141.6 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pirin PF02678.16 EGG21659.1 - 4.5e-35 119.9 0.0 1.3e-34 118.4 0.0 1.9 1 0 0 1 1 1 1 Pirin Helicase_C PF00271.31 EGG21659.1 - 3.4e-32 111.1 4.1 2.4e-29 101.9 0.4 3.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Pirin_C PF05726.13 EGG21659.1 - 3e-30 104.6 0.0 1.8e-29 102.2 0.0 2.4 2 0 0 2 2 2 1 Pirin C-terminal cupin domain KOW PF00467.29 EGG21659.1 - 0.099 12.6 0.1 0.41 10.7 0.1 2.0 1 0 0 1 1 1 0 KOW motif KH_2 PF07650.17 EGG21659.1 - 0.13 12.1 2.6 0.29 11.0 0.0 2.9 3 0 0 3 3 3 0 KH domain Usp PF00582.26 EGG21660.1 - 3.7e-19 69.6 0.0 1.3e-17 64.7 0.0 2.0 1 1 0 1 1 1 1 Universal stress protein family DUF799 PF05643.11 EGG21660.1 - 0.04 13.5 0.0 0.092 12.3 0.0 1.4 1 1 0 2 2 2 0 Putative bacterial lipoprotein (DUF799) Peptidase_M8 PF01457.16 EGG21661.1 - 2.3e-114 383.0 7.4 5e-60 203.7 2.8 3.0 2 2 0 2 2 2 2 Leishmanolysin MTHFR_C PF12225.8 EGG21661.1 - 0.0025 17.4 2.4 0.63 9.7 0.1 2.8 2 0 0 2 2 2 2 Methylene-tetrahydrofolate reductase C terminal Lipase3_N PF03893.16 EGG21661.1 - 0.021 14.9 0.1 12 6.0 0.0 2.8 2 0 0 2 2 2 0 Lipase 3 N-terminal region Peptidase_M10 PF00413.24 EGG21661.1 - 0.088 12.6 0.0 3 7.7 0.0 2.2 2 0 0 2 2 2 0 Matrixin PH PF00169.29 EGG21662.1 - 3.7e-13 49.9 0.5 3.7e-13 49.9 0.5 2.5 2 0 0 2 2 2 1 PH domain NACHT_N PF17100.5 EGG21662.1 - 2.8 7.8 10.1 9.5 6.0 10.1 1.9 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase HEPN_Swt1 PF18731.1 EGG21663.1 - 2.4e-09 37.5 0.1 2.4e-09 37.5 0.1 5.0 4 1 1 5 5 5 1 Swt1-like HEPN zf-MYND PF01753.18 EGG21664.1 - 2.5e-06 27.5 19.7 4.3e-06 26.7 19.7 1.4 1 1 0 1 1 1 1 MYND finger RhoGEF PF00621.20 EGG21666.1 - 7.2e-51 173.0 0.6 4.2e-50 170.5 0.2 2.2 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 EGG21666.1 - 2.3e-16 59.7 6.6 7.5e-16 58.0 6.6 1.9 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 EGG21666.1 - 0.0001 22.8 0.0 0.00034 21.1 0.0 2.0 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.16 EGG21666.1 - 0.013 15.7 1.4 0.013 15.7 1.4 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger PH_13 PF16652.5 EGG21666.1 - 0.063 13.1 0.6 4.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain IBR PF01485.21 EGG21666.1 - 0.096 12.9 3.6 0.28 11.4 3.6 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-B_box PF00643.24 EGG21666.1 - 0.31 11.2 6.4 1.4 9.1 6.4 2.1 1 0 0 1 1 1 0 B-box zinc finger DnaJ_C PF01556.18 EGG21667.1 - 6e-34 117.3 0.9 8.6e-34 116.8 0.9 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGG21667.1 - 1.9e-25 88.8 0.5 3.1e-25 88.1 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGG21667.1 - 5.2e-14 52.4 20.9 9.9e-14 51.5 20.9 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGG21667.1 - 2.5e-05 24.2 8.1 0.0011 18.8 0.8 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGG21667.1 - 0.00085 19.3 8.3 0.027 14.5 2.1 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GRP PF07172.11 EGG21667.1 - 0.25 12.1 7.7 0.7 10.6 7.7 1.8 1 0 0 1 1 1 0 Glycine rich protein family TackOD1 PF18551.1 EGG21667.1 - 3.1 7.4 8.3 1.2 8.8 1.1 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf-C3HC4_3 PF13920.6 EGG21667.1 - 3.1 7.7 8.5 1.6 8.7 1.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 EGG21667.1 - 4 7.6 13.2 68 3.6 13.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 EGG21667.1 - 7 6.9 12.7 0.73 10.0 3.1 2.4 1 1 1 2 2 2 0 zinc RING finger of MSL2 HATPase_c PF02518.26 EGG21668.1 - 5.1e-54 181.6 0.3 1.2e-25 90.1 0.0 3.0 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGG21668.1 - 3.7e-43 146.2 0.4 2.1e-24 85.8 0.1 3.6 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 EGG21668.1 - 2.2e-29 101.3 3.2 5.1e-14 52.1 0.1 3.5 3 0 0 3 3 3 2 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 EGG21668.1 - 6.2e-06 26.4 0.0 2.2e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EGG21668.1 - 0.00057 20.1 0.0 0.0038 17.5 0.0 2.5 2 0 0 2 2 2 1 PAS domain NOD PF06816.13 EGG21668.1 - 0.026 14.1 0.4 1.9 8.2 0.1 2.7 2 0 0 2 2 2 0 NOTCH protein VPS9 PF02204.18 EGG21669.1 - 3.1e-22 78.7 0.1 1.3e-21 76.8 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RGCC PF15151.6 EGG21669.1 - 0.0036 17.5 0.8 0.0036 17.5 0.8 2.3 2 0 0 2 2 2 1 Response gene to complement 32 protein family COG6 PF06419.11 EGG21670.1 - 1.4e-187 624.8 25.0 1.6e-187 624.6 25.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Protoglobin PF11563.8 EGG21670.1 - 0.19 11.6 1.8 1.1 9.1 0.2 2.8 2 2 1 3 3 3 0 Protoglobin DUF5344 PF17279.2 EGG21670.1 - 7 7.3 13.4 0.5 11.0 3.4 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5344) IMPDH PF00478.25 EGG21671.1 - 4.3e-133 443.6 3.4 6e-133 443.1 3.4 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CLU PF13236.6 EGG21671.1 - 7.3e-53 179.7 0.0 1.5e-52 178.7 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria TPR_12 PF13424.6 EGG21671.1 - 4.3e-32 110.2 2.2 1.5e-12 47.6 0.0 4.5 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGG21671.1 - 6.3e-14 51.3 0.0 0.0069 16.2 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat CBS PF00571.28 EGG21671.1 - 1.4e-13 51.0 0.2 2.6e-08 34.2 0.0 2.9 2 0 0 2 2 2 2 CBS domain eIF3_p135 PF12807.7 EGG21671.1 - 8.4e-12 45.5 1.5 4.4e-11 43.1 1.5 2.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_2 PF07719.17 EGG21671.1 - 2.1e-11 43.0 0.9 0.00054 19.9 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGG21671.1 - 1e-10 40.9 6.0 0.0014 18.3 0.0 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG21671.1 - 2.2e-10 39.9 8.4 0.0029 17.7 0.2 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat NMO PF03060.15 EGG21671.1 - 1.4e-08 34.5 0.6 1.1e-05 25.1 0.3 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EGG21671.1 - 1.2e-06 27.8 0.5 2.5e-06 26.8 0.5 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TPR_7 PF13176.6 EGG21671.1 - 2.7e-06 27.0 0.3 0.23 11.5 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGG21671.1 - 0.0012 18.3 0.0 0.0053 16.2 0.0 1.9 2 0 0 2 2 2 1 MalT-like TPR region ThiG PF05690.14 EGG21671.1 - 0.0019 17.6 0.1 0.0036 16.6 0.1 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EGG21671.1 - 0.002 17.6 0.8 0.0062 16.0 0.2 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.17 EGG21671.1 - 0.11 11.6 1.2 0.22 10.6 1.2 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 EGG21671.1 - 0.11 11.6 0.7 0.29 10.3 0.7 1.6 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF2225 PF09986.9 EGG21671.1 - 0.86 9.3 10.0 3.1 7.5 1.2 3.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Mad3_BUB1_I PF08311.12 EGG21671.1 - 2.3 8.2 4.7 22 5.0 0.1 3.6 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 Ribosomal_L7Ae PF01248.26 EGG21672.1 - 5e-07 29.4 0.0 2e-06 27.4 0.0 2.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ThiF PF00899.21 EGG21673.1 - 1.4e-35 122.8 0.0 2.3e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 EGG21673.1 - 0.00018 21.9 0.0 0.00065 20.1 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EGG21673.1 - 0.00025 21.3 0.4 0.0032 17.7 0.4 2.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EGG21673.1 - 0.11 12.1 0.9 0.3 10.7 0.0 2.2 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EGG21673.1 - 0.19 12.0 1.4 0.33 11.2 0.2 2.0 2 0 0 2 2 2 0 TrkA-N domain Rubis-subs-bind PF09273.11 EGG21674.1 - 2.6e-21 76.7 0.0 5.5e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EGG21674.1 - 0.056 13.8 0.0 0.15 12.4 0.0 1.9 1 1 0 1 1 1 0 SET domain TK PF00265.18 EGG21674.1 - 0.19 11.5 0.1 0.34 10.8 0.1 1.3 1 0 0 1 1 1 0 Thymidine kinase DNA_repr_REX1B PF14966.6 EGG21674.1 - 0.28 11.9 1.1 0.55 10.9 0.1 2.0 2 0 0 2 2 2 0 DNA repair REX1-B DUF423 PF04241.15 EGG21675.1 - 7.1e-26 90.2 0.8 9.4e-26 89.8 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) THF_DHG_CYH PF00763.23 EGG21677.1 - 0.2 11.9 1.9 7.2 6.9 0.1 2.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Sulfotransfer_2 PF03567.14 EGG21678.1 - 1.3e-13 51.4 0.6 3.2e-13 50.2 0.6 1.6 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 EGG21678.1 - 1.1e-05 24.5 0.5 5.6e-05 22.2 0.5 2.1 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase LRR_6 PF13516.6 EGG21680.1 - 0.89 9.8 0.0 0.89 9.8 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich repeat CRAL_TRIO PF00650.20 EGG21683.1 - 8.2e-46 155.6 0.2 1.2e-45 155.1 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGG21683.1 - 8.9e-12 45.0 0.8 2.4e-11 43.7 0.8 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGG21683.1 - 3.2e-07 30.6 0.1 5.5e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Zn_ribbon_2 PF12674.7 EGG21683.1 - 0.031 14.9 1.2 0.15 12.7 0.2 2.3 2 0 0 2 2 2 0 Putative zinc ribbon domain Mito_carr PF00153.27 EGG21684.1 - 7.1e-56 186.1 1.9 6.2e-21 74.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF410 PF04190.13 EGG21685.1 - 1e-70 238.5 0.1 1.2e-70 238.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_2 PF07719.17 EGG21685.1 - 0.058 13.5 0.4 0.3 11.3 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG21685.1 - 0.15 12.3 0.6 1.7 9.0 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Clat_adaptor_s PF01217.20 EGG21687.1 - 4.3e-08 33.2 4.1 7.5e-08 32.4 4.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1084 PF06454.11 EGG21688.1 - 2.8e-11 43.3 24.2 1.3e-10 41.1 24.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) F-box-like PF12937.7 EGG21690.1 - 0.075 12.9 0.1 0.29 11.1 0.1 2.1 1 1 0 1 1 1 0 F-box-like G10 PF01125.17 EGG21691.1 - 8.2e-61 204.1 11.9 9.7e-61 203.8 11.9 1.0 1 0 0 1 1 1 1 G10 protein dCMP_cyt_deam_1 PF00383.23 EGG21693.1 - 8e-13 48.1 0.0 8e-13 48.1 0.0 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGG21693.1 - 3.1e-10 39.9 0.1 7.1e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EGG21693.1 - 0.14 12.2 1.0 2.1 8.4 0.1 2.4 2 1 0 2 2 2 0 Bd3614-like deaminase S_layer_C PF05124.12 EGG21694.1 - 0.00027 21.0 0.0 0.00053 20.0 0.0 1.4 1 0 0 1 1 1 1 S-layer like family, C-terminal region Peptidase_S9 PF00326.21 EGG21694.1 - 0.01 15.4 0.5 0.041 13.3 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 EGG21694.1 - 0.022 14.3 0.2 0.048 13.1 0.2 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 EGG21694.1 - 0.16 11.2 0.2 4.1 6.6 0.0 2.3 1 1 1 2 2 2 0 Serine aminopeptidase, S33 CRM1_C PF08767.11 EGG21695.1 - 1.4e-103 346.4 11.2 1.4e-103 346.4 11.2 3.4 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 EGG21695.1 - 1.6e-31 109.4 7.5 1.6e-31 109.4 7.5 4.4 5 1 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EGG21695.1 - 5.9e-27 93.1 1.2 2.6e-26 91.1 1.2 2.2 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat PF18777.1 EGG21695.1 - 4.2e-17 61.4 0.5 1.6e-16 59.5 0.5 2.1 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EGG21695.1 - 2.6e-12 46.5 0.1 2.6e-12 46.5 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain GRIP PF01465.20 EGG21695.1 - 0.011 15.7 0.0 0.052 13.5 0.0 2.3 1 0 0 1 1 1 0 GRIP domain Vac14_Fab1_bd PF12755.7 EGG21695.1 - 0.11 13.1 0.7 3.2 8.4 0.0 3.5 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region MHB PF16525.5 EGG21695.1 - 0.13 12.5 0.3 0.88 9.9 0.1 2.5 2 0 0 2 2 2 0 Haemophore, haem-binding CLASP_N PF12348.8 EGG21695.1 - 0.4 10.2 5.7 1.9 8.0 0.2 3.8 4 0 0 4 4 4 0 CLASP N terminal Ank_2 PF12796.7 EGG21696.1 - 2.5e-91 300.4 22.5 1.6e-13 51.0 0.2 7.2 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG21696.1 - 7.4e-67 220.9 6.4 4.4e-11 43.1 0.1 10.4 2 2 9 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG21696.1 - 9.3e-64 203.8 0.5 7.2e-05 22.9 0.0 13.5 13 0 0 13 13 13 11 Ankyrin repeat Ank PF00023.30 EGG21696.1 - 6.7e-53 174.9 12.0 9e-05 22.7 0.0 13.3 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 EGG21696.1 - 1.9e-52 174.6 8.9 1.7e-08 34.6 0.0 9.6 5 3 5 10 10 10 9 Ankyrin repeats (many copies) CH PF00307.31 EGG21696.1 - 3.4e-16 59.4 0.4 7.2e-16 58.3 0.4 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 EGG21696.1 - 0.0058 16.8 0.1 0.018 15.3 0.1 1.8 1 0 0 1 1 1 1 CDC24 Calponin JAB PF01398.21 EGG21697.1 - 1.3e-19 70.3 0.0 1.3e-19 70.3 0.0 2.9 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 EGG21697.1 - 2.2e-18 66.5 4.0 2.2e-18 66.5 4.0 2.9 2 1 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.6 EGG21697.1 - 2.1e-05 24.2 1.1 4.7e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain TPR_8 PF13181.6 EGG21697.1 - 0.99 9.8 3.4 2.7 8.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MaoC_dehydratas PF01575.19 EGG21699.1 - 1e-23 83.2 0.0 1.5e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EGG21699.1 - 1e-07 32.1 0.0 1.4e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Peptidase_M16_M PF16187.5 EGG21700.1 - 3.6e-50 170.8 5.5 7.3e-50 169.8 5.5 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EGG21700.1 - 6.4e-35 120.3 0.0 1.5e-34 119.1 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGG21700.1 - 1.6e-24 86.9 2.8 3.8e-15 56.4 0.0 3.9 4 0 0 4 4 4 3 Peptidase M16 inactive domain MFS_1 PF07690.16 EGG21701.1 - 6.8e-34 117.3 40.1 2.4e-26 92.5 26.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 EGG21701.1 - 3.9e-21 75.4 11.3 3.9e-21 75.4 11.3 3.1 2 2 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 EGG21701.1 - 4.6e-06 25.8 3.3 4.6e-06 25.8 3.3 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter DUF4519 PF15012.6 EGG21701.1 - 0.096 12.9 1.9 0.55 10.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Pkinase PF00069.25 EGG21702.1 - 9.9e-75 251.3 0.0 2.2e-74 250.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21702.1 - 3.7e-49 167.4 0.0 7.5e-49 166.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG21702.1 - 2.3e-06 26.7 0.0 5.1e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Arm PF00514.23 EGG21702.1 - 0.00023 21.1 4.7 7.3 6.8 0.0 6.8 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 EGG21702.1 - 0.00064 19.1 0.0 0.021 14.2 0.0 2.4 2 0 0 2 2 2 1 Kinase-like RL PF17797.1 EGG21702.1 - 0.0015 18.4 0.1 3.2 7.8 0.0 2.7 2 0 0 2 2 2 2 RL domain Adaptin_N PF01602.20 EGG21702.1 - 0.0031 16.1 1.9 0.0031 16.1 1.9 2.9 2 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 EGG21702.1 - 0.0047 17.0 4.8 0.037 14.1 1.6 3.2 2 0 0 2 2 2 1 V-ATPase subunit H RICTOR_N PF14664.6 EGG21702.1 - 0.0072 15.4 2.4 2.4 7.1 0.1 3.6 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, N-term RIO1 PF01163.22 EGG21702.1 - 0.02 14.5 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 RIO1 family HEAT PF02985.22 EGG21702.1 - 0.02 15.1 0.5 0.97 9.9 0.0 4.1 5 0 0 5 5 4 0 HEAT repeat Kdo PF06293.14 EGG21702.1 - 0.031 13.6 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGG21702.1 - 0.033 13.8 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CBF PF03914.17 EGG21702.1 - 0.16 12.0 1.3 0.71 9.9 0.1 2.7 2 1 0 2 2 2 0 CBF/Mak21 family ParcG PF10274.9 EGG21702.1 - 0.18 11.9 2.5 2.3 8.3 0.5 2.8 2 0 0 2 2 2 0 Parkin co-regulated protein CSTF2_hinge PF14327.6 EGG21702.1 - 0.81 10.2 5.9 0.44 11.0 0.1 3.3 3 0 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 Proteasom_PSMB PF10508.9 EGG21702.1 - 2.6 6.4 7.8 0.25 9.8 0.1 3.0 4 0 0 4 4 4 0 Proteasome non-ATPase 26S subunit Spc7 PF08317.11 EGG21704.1 - 5.6e-12 45.2 10.0 5.6e-12 45.2 10.0 4.7 4 1 1 5 5 5 2 Spc7 kinetochore protein Knl1_RWD_C PF18210.1 EGG21704.1 - 0.00032 21.1 0.7 0.00098 19.6 0.0 2.1 2 0 0 2 2 2 1 Knl1 RWD C-terminal domain SNARE PF05739.19 EGG21705.1 - 0.00027 20.9 3.8 0.002 18.1 0.6 2.5 2 0 0 2 2 2 1 SNARE domain Phage_Gp23 PF10669.9 EGG21705.1 - 0.048 14.0 3.0 0.1 12.9 0.4 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF1664 PF07889.12 EGG21705.1 - 0.43 10.6 9.6 4.5 7.3 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ACPS PF01648.20 EGG21706.1 - 5.5e-22 78.0 0.0 7.2e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EGG21706.1 - 0.00023 21.2 0.5 0.8 9.9 0.0 2.6 3 0 0 3 3 3 2 4'-phosphopantetheinyl transferase N-terminal domain FAD_binding_2 PF00890.24 EGG21707.1 - 7.6e-125 417.3 3.2 9.7e-125 416.9 3.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EGG21707.1 - 6.9e-42 142.5 0.6 1.1e-41 141.8 0.6 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 EGG21707.1 - 1.4e-05 24.4 0.2 0.029 13.6 0.1 2.8 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.22 EGG21707.1 - 2.4e-05 23.6 1.2 0.044 12.8 1.6 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EGG21707.1 - 4.2e-05 22.9 0.4 0.001 18.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGG21707.1 - 0.0029 16.9 0.3 0.0056 16.0 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Dor1 PF04124.12 EGG21707.1 - 0.0032 16.2 0.4 0.0052 15.5 0.4 1.2 1 0 0 1 1 1 1 Dor1-like family DAO PF01266.24 EGG21707.1 - 0.0066 16.1 1.5 0.026 14.1 1.5 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG21707.1 - 0.053 12.2 0.3 0.13 10.9 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 EGG21707.1 - 4.6 6.4 4.8 1.1 8.4 1.1 1.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase COX6B PF02297.17 EGG21708.1 - 0.29 11.4 6.4 4.8 7.5 0.1 2.5 2 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb GCK PF07802.11 EGG21708.1 - 0.33 11.4 4.1 0.58 10.6 0.3 2.4 2 1 1 3 3 3 0 GCK domain DUF3819 PF12842.7 EGG21708.1 - 1.7 8.5 7.2 0.9 9.5 1.1 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF3819) Pet191_N PF10203.9 EGG21708.1 - 6.2 7.2 12.9 73 3.8 8.8 3.1 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EGG21708.1 - 9.7 6.3 13.6 2.4 8.2 3.4 2.7 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, AhpC-TSA PF00578.21 EGG21709.1 - 7.1e-36 122.9 0.0 9.8e-36 122.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGG21709.1 - 5.8e-13 48.8 0.0 8.5e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGG21709.1 - 1.2e-09 37.8 0.0 2.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EGG21709.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 SCO1/SenC Pyr_redox_2 PF07992.14 EGG21711.1 - 2e-46 158.6 0.0 3.3e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EGG21711.1 - 4.2e-13 47.8 1.0 1.9e-05 23.9 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGG21711.1 - 2.6e-11 42.5 0.9 7.4e-05 22.4 0.5 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGG21711.1 - 2.7e-10 39.2 4.9 5.2e-05 22.5 1.1 2.5 2 0 0 2 2 2 2 EF hand Pyr_redox PF00070.27 EGG21711.1 - 8.1e-10 39.1 0.0 7.7e-08 32.8 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 EGG21711.1 - 1.7e-09 38.0 0.2 4.6e-09 36.6 0.2 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGG21711.1 - 1.1e-05 25.2 0.5 0.2 11.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair ArAE_2_N PF10337.9 EGG21711.1 - 0.0026 16.9 0.1 0.0049 16.0 0.1 1.4 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal SPARC_Ca_bdg PF10591.9 EGG21711.1 - 1.5 9.2 10.5 14 6.1 0.1 3.4 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Fe-ADH PF00465.19 EGG21713.1 - 7e-103 344.2 0.0 8.4e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGG21713.1 - 4.1e-08 33.2 0.0 0.00065 19.5 0.0 2.4 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Pkinase PF00069.25 EGG21714.1 - 6.9e-68 228.9 0.0 1.3e-67 228.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Calpain_III PF01067.22 EGG21714.1 - 5.5e-60 201.7 6.0 1.1e-18 67.8 0.0 5.6 5 1 0 5 5 5 4 Calpain large subunit, domain III Pkinase_Tyr PF07714.17 EGG21714.1 - 3.7e-49 167.3 0.0 5.6e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG21714.1 - 0.00012 21.1 0.0 0.00012 21.1 0.0 2.7 3 0 0 3 3 3 1 Fungal protein kinase KIND PF16474.5 EGG21714.1 - 0.058 13.3 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Kinase-like PF14531.6 EGG21714.1 - 0.093 12.0 0.0 0.38 10.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Abi_2 PF07751.11 EGG21714.1 - 0.1 12.9 0.2 0.1 12.9 0.2 3.1 3 0 0 3 3 3 0 Abi-like protein TFIIA PF03153.13 EGG21714.1 - 6.2 6.7 32.7 11 5.8 32.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PK PF00224.21 EGG21715.1 - 6.3e-150 498.9 8.0 8.6e-150 498.4 8.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGG21715.1 - 1.7e-26 92.7 0.4 1e-25 90.3 0.2 2.3 2 1 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGG21715.1 - 0.045 12.9 0.7 0.099 11.8 0.7 1.6 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family DUF4677 PF15726.5 EGG21715.1 - 0.09 12.9 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) Glyco_hydro_38N PF01074.22 EGG21717.1 - 4.6e-80 269.1 0.7 7.4e-80 268.4 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGG21717.1 - 6e-57 193.2 0.0 9.1e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGG21717.1 - 1.1e-24 86.4 0.1 5.1e-24 84.2 0.2 2.1 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EGG21717.1 - 5e-10 39.4 0.0 1.1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 EGG21717.1 - 0.051 12.8 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 GatB_Yqey PF02637.18 EGG21718.1 - 0.011 15.7 10.7 0.019 14.8 10.7 1.4 1 0 0 1 1 1 0 GatB domain W2 PF02020.18 EGG21719.1 - 4.5e-16 58.7 5.4 4.5e-16 58.7 5.4 3.5 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 EGG21719.1 - 5.8e-13 49.0 0.0 1.5e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EGG21719.1 - 3.2e-11 42.5 17.2 2.4e-05 23.8 8.3 4.3 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EGG21719.1 - 0.0015 16.8 1.5 0.0032 15.7 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EGG21719.1 - 0.0026 17.5 11.6 0.28 11.0 0.5 4.3 3 2 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 EGG21719.1 - 0.0041 17.5 0.0 0.0085 16.5 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EGG21719.1 - 0.28 10.1 7.9 0.17 10.8 2.6 2.6 2 1 1 3 3 3 0 L-fucokinase Cpn60_TCP1 PF00118.24 EGG21720.1 - 3.6e-31 108.3 13.1 2.9e-29 102.1 10.6 3.2 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family HAGH_C PF16123.5 EGG21720.1 - 0.17 12.4 3.4 0.68 10.5 1.0 2.7 2 0 0 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus DUF4834 PF16118.5 EGG21720.1 - 0.25 12.3 24.5 0.53 11.3 4.8 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Mucin PF01456.17 EGG21720.1 - 4.5 7.3 6.5 7.6 6.5 3.5 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Yip1 PF04893.17 EGG21721.1 - 3.2e-13 49.8 19.0 4.7e-13 49.2 19.0 1.2 1 0 0 1 1 1 1 Yip1 domain P34-Arc PF04045.14 EGG21722.1 - 2.1e-84 283.0 0.0 2.5e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Phage_int_SAM_5 PF13102.6 EGG21722.1 - 0.056 13.8 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 Phage integrase SAM-like domain Thiamine_BP PF01910.17 EGG21722.1 - 0.17 11.8 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Thiamine-binding protein Pterin_4a PF01329.19 EGG21723.1 - 3e-31 107.4 0.1 3.6e-31 107.2 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DUF3979 PF13141.6 EGG21723.1 - 0.061 13.6 0.0 0.075 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) SRF-TF PF00319.18 EGG21725.1 - 7.2e-20 70.2 0.2 1.1e-19 69.6 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) UPF0565 PF10561.9 EGG21725.1 - 0.56 9.3 6.5 0.86 8.7 6.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Borrelia_P83 PF05262.11 EGG21725.1 - 0.67 8.4 15.4 0.95 7.9 15.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein LMBR1 PF04791.16 EGG21725.1 - 0.73 8.7 8.5 0.99 8.2 8.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DREPP PF05558.12 EGG21725.1 - 0.92 9.4 6.5 0.62 9.9 4.4 1.7 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide SID-1_RNA_chan PF13965.6 EGG21725.1 - 0.99 7.7 4.1 1.4 7.2 4.1 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AAA_23 PF13476.6 EGG21725.1 - 1.4 9.4 19.4 0.025 15.1 12.5 1.6 2 0 0 2 2 2 0 AAA domain Membralin PF09746.9 EGG21725.1 - 3 6.8 10.3 5.5 5.9 10.3 1.4 1 0 0 1 1 1 0 Tumour-associated protein XRN_M PF17846.1 EGG21725.1 - 3.6 6.4 13.2 6.2 5.7 13.2 1.3 1 0 0 1 1 1 0 Xrn1 helical domain V_ATPase_I PF01496.19 EGG21725.1 - 7.7 4.3 16.7 13 3.6 16.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Asp-B-Hydro_N PF05279.11 EGG21725.1 - 8.4 6.4 12.4 16 5.4 12.4 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDE_Tnp_4 PF13359.6 EGG21726.1 - 3.6e-05 23.5 0.1 9.2e-05 22.2 0.0 1.6 1 1 1 2 2 2 1 DDE superfamily endonuclease DNA_pol_phi PF04931.13 EGG21728.1 - 1.1e-106 357.8 36.5 1.1e-106 357.8 36.5 4.5 3 1 0 3 3 3 1 DNA polymerase phi PIP49_N PF14875.6 EGG21728.1 - 0.047 13.5 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 ThiF PF00899.21 EGG21729.1 - 7.6e-57 192.5 0.3 1e-56 192.0 0.3 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EGG21729.1 - 0.00046 20.7 0.1 0.00092 19.7 0.1 1.5 1 0 0 1 1 1 1 Rhodanese-like domain FAD_binding_3 PF01494.19 EGG21729.1 - 0.039 13.2 0.1 0.051 12.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 EGG21729.1 - 0.049 13.2 0.7 0.075 12.6 0.7 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 EGG21729.1 - 0.053 13.8 1.4 0.19 12.0 1.4 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EGG21729.1 - 0.072 13.1 3.0 0.076 13.1 0.2 2.3 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 EGG21729.1 - 0.1 12.2 0.2 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DapB_N PF01113.20 EGG21729.1 - 0.17 12.0 0.5 0.42 10.7 0.5 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ApbA PF02558.16 EGG21729.1 - 0.36 10.4 2.7 1.1 8.8 2.1 2.2 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Ocnus PF05005.15 EGG21730.1 - 4.2e-15 55.8 0.2 9.2e-13 48.3 0.0 2.2 2 0 0 2 2 2 1 Janus/Ocnus family (Ocnus) Spt5_N PF11942.8 EGG21730.1 - 0.014 16.3 5.6 0.025 15.6 5.6 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SDA1 PF05285.12 EGG21730.1 - 0.039 13.4 3.1 0.042 13.3 3.1 1.1 1 0 0 1 1 1 0 SDA1 RE_NgoFVII PF09565.10 EGG21730.1 - 0.053 12.8 0.1 0.053 12.8 0.1 1.4 2 0 0 2 2 1 0 NgoFVII restriction endonuclease ATP13 PF12921.7 EGG21730.1 - 0.086 12.7 0.3 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ATPase expression RXT2_N PF08595.11 EGG21730.1 - 0.15 12.1 3.3 0.28 11.2 3.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 EGG21730.1 - 0.16 10.3 1.6 0.17 10.2 1.6 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 EGG21730.1 - 0.19 11.8 1.7 0.2 11.8 1.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Roughex PF06020.11 EGG21730.1 - 0.59 9.2 5.5 2.3 7.2 6.5 1.4 2 0 0 2 2 2 0 Drosophila roughex protein RRN3 PF05327.11 EGG21730.1 - 0.94 7.9 4.2 1.1 7.7 4.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 EGG21730.1 - 4.9 5.1 8.2 6.1 4.8 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi AAA_2 PF07724.14 EGG21732.1 - 6.7e-50 169.5 0.3 2.1e-48 164.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGG21732.1 - 1.2e-35 121.5 1.3 1.2e-35 121.5 1.3 2.6 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EGG21732.1 - 9.5e-28 96.1 0.1 3.3e-27 94.4 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EGG21732.1 - 3.3e-22 79.3 0.3 1.9e-12 47.7 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGG21732.1 - 3.1e-15 56.4 0.0 5.3e-09 36.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGG21732.1 - 1.8e-11 44.7 1.0 2.8e-05 24.5 0.2 4.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EGG21732.1 - 1.2e-08 35.3 3.7 0.011 16.1 0.0 5.4 4 1 1 5 5 5 2 AAA domain Sigma54_activat PF00158.26 EGG21732.1 - 8.9e-07 28.8 0.0 0.00089 19.0 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain TniB PF05621.11 EGG21732.1 - 1.4e-06 27.9 0.0 0.006 16.0 0.0 3.7 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 EGG21732.1 - 1.6e-05 24.5 0.0 0.08 12.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGG21732.1 - 3.6e-05 23.6 0.0 0.059 13.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGG21732.1 - 4.8e-05 22.8 0.0 0.17 11.2 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGG21732.1 - 5.3e-05 23.3 0.2 0.058 13.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 EGG21732.1 - 0.00015 22.3 2.4 0.39 11.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain Roc PF08477.13 EGG21732.1 - 0.00032 20.9 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EGG21732.1 - 0.00039 20.8 0.0 2.2 8.7 0.0 3.2 3 0 0 3 3 2 2 RNA helicase RuvB_N PF05496.12 EGG21732.1 - 0.00047 19.9 2.9 0.54 10.0 0.0 3.7 3 1 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EGG21732.1 - 0.00097 19.1 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EGG21732.1 - 0.0011 18.7 0.0 0.57 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EGG21732.1 - 0.0013 18.8 5.4 3.2 7.6 0.1 4.6 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EGG21732.1 - 0.0013 18.7 0.0 0.22 11.4 0.0 3.0 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 EGG21732.1 - 0.0017 18.3 3.3 1 9.3 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase AAA_28 PF13521.6 EGG21732.1 - 0.0063 16.8 0.0 5.4 7.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGG21732.1 - 0.0093 16.3 0.0 1.3 9.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EGG21732.1 - 0.012 15.8 0.0 6.9 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGG21732.1 - 0.016 14.4 0.1 1 8.5 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 EGG21732.1 - 0.018 14.8 0.0 0.89 9.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ResIII PF04851.15 EGG21732.1 - 0.027 14.5 0.0 8 6.4 0.0 3.3 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 EGG21732.1 - 0.028 14.0 0.0 3 7.4 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EGG21732.1 - 0.035 13.9 0.0 12 5.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_3 PF07726.11 EGG21732.1 - 0.055 13.3 0.1 23 4.8 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGG21732.1 - 0.059 12.9 0.0 1.1 8.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EGG21732.1 - 0.092 13.3 3.1 6.2 7.3 0.0 3.4 4 0 0 4 4 3 0 ABC transporter MMR_HSR1 PF01926.23 EGG21732.1 - 0.097 12.8 0.0 15 5.7 0.0 3.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 EGG21732.1 - 0.72 9.9 11.7 19 5.3 3.3 4.0 4 0 0 4 4 4 0 Helicase HerA, central domain UPF0242 PF06785.11 EGG21732.1 - 1 9.4 10.1 2.4 8.2 10.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 EGG21732.1 - 1.2 9.8 9.6 11 6.7 4.9 2.8 1 1 1 2 2 2 0 SlyX AAA_23 PF13476.6 EGG21732.1 - 4.1 7.8 21.4 25 5.3 0.0 4.0 3 1 0 3 3 3 0 AAA domain Fib_alpha PF08702.10 EGG21732.1 - 6.3 7.0 10.3 0.78 9.9 1.7 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HSP20 PF00011.21 EGG21733.1 - 2.4e-20 72.6 1.1 4.4e-20 71.7 1.1 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG21733.1 - 9.4e-06 25.1 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF3408 PF11888.8 EGG21733.1 - 0.066 13.4 2.9 5.9 7.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) MTABC_N PF16185.5 EGG21733.1 - 2.6 7.5 4.2 0.81 9.1 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region OCRE PF17780.1 EGG21734.1 - 0.069 13.2 2.1 3.2 7.9 0.0 2.6 2 0 0 2 2 2 0 OCRE domain DUF3127 PF11325.8 EGG21734.1 - 0.12 12.6 0.1 9.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3127) DUF5074 PF16819.5 EGG21734.1 - 0.8 9.8 7.3 2.5 8.2 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5074) AAA_19 PF13245.6 EGG21735.1 - 0.1 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGG21735.1 - 0.15 12.3 0.0 0.75 10.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG21735.1 - 0.17 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NODP PF07684.12 EGG21738.1 - 0.085 13.0 0.5 0.2 11.9 0.5 1.7 1 0 0 1 1 1 0 NOTCH protein Med3 PF11593.8 EGG21738.1 - 0.89 8.7 2.3 1.2 8.2 2.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Fzo_mitofusin PF04799.13 EGG21738.1 - 1.7 8.2 3.5 0.89 9.1 0.3 1.9 2 0 0 2 2 2 0 fzo-like conserved region Beta-lactamase PF00144.24 EGG21742.1 - 1.1e-36 126.7 0.0 1.8e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Rad60-SLD PF11976.8 EGG21742.1 - 5.4e-19 67.8 1.4 9.2e-12 44.6 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGG21742.1 - 2.7e-05 23.8 0.6 0.016 14.9 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin family TUG-UBL1 PF11470.8 EGG21742.1 - 0.014 15.6 0.4 0.24 11.6 0.1 2.6 2 0 0 2 2 2 0 TUG ubiquitin-like domain HECT PF00632.25 EGG21745.1 - 2e-91 306.7 0.4 3.8e-91 305.8 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF3552 PF12072.8 EGG21746.1 - 0.0065 15.9 3.8 0.0065 15.9 3.8 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3552) Ank_2 PF12796.7 EGG21747.1 - 9e-35 119.1 19.9 7.3e-08 32.9 0.2 4.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG21747.1 - 5.3e-24 84.3 6.4 8.4e-06 26.2 0.1 6.3 5 2 0 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG21747.1 - 2.1e-18 66.2 7.8 0.005 17.1 0.0 7.9 1 1 8 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG21747.1 - 1.6e-12 46.4 2.7 4.4 8.2 0.0 9.0 9 1 1 10 10 10 2 Ankyrin repeat Ank PF00023.30 EGG21747.1 - 3.1e-07 30.5 3.0 17 6.1 0.1 7.4 3 2 3 6 6 6 1 Ankyrin repeat DUF5049 PF16468.5 EGG21747.1 - 0.0013 18.6 1.6 19 5.2 0.1 6.3 7 1 1 8 8 8 1 Domain of unknown function (DUF5049) Mucin PF01456.17 EGG21747.1 - 0.8 9.7 9.3 2.8 7.9 0.7 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Monooxygenase_B PF04744.12 EGG21748.1 - 0.01 14.7 0.3 0.013 14.4 0.3 1.2 1 0 0 1 1 1 0 Monooxygenase subunit B protein DUF3446 PF11928.8 EGG21748.1 - 3.9 7.9 13.7 0.3 11.4 2.4 2.5 3 0 0 3 3 3 0 Early growth response N-terminal domain SNAPc19 PF15497.6 EGG21749.1 - 0.14 12.7 1.9 0.14 12.6 0.1 1.8 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Pribosyltran_N PF13793.6 EGG21750.1 - 3e-18 65.8 0.1 3.4e-18 65.7 0.1 1.0 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGG21751.1 - 5.9e-40 137.3 3.7 4.5e-37 127.9 1.2 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EGG21751.1 - 8.3e-17 61.2 4.0 1.9e-16 60.0 0.1 2.9 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EGG21751.1 - 1.2e-16 60.7 1.3 3.3e-16 59.2 1.3 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGG21751.1 - 0.048 13.1 0.2 0.1 12.0 0.2 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase SNARE PF05739.19 EGG21752.1 - 2.6e-05 24.1 0.0 2.6e-05 24.1 0.0 3.5 5 0 0 5 5 5 1 SNARE domain Syntaxin PF00804.25 EGG21752.1 - 0.0058 16.3 17.5 0.026 14.2 17.5 1.9 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 EGG21752.1 - 0.0085 15.9 1.7 0.0085 15.9 1.7 2.4 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Phage_gp53 PF11246.8 EGG21752.1 - 0.01 15.5 1.4 0.029 14.1 0.5 2.0 2 0 0 2 2 2 0 Base plate wedge protein 53 F-112 PF09645.10 EGG21752.1 - 0.032 14.3 5.8 0.049 13.7 2.6 2.3 1 1 0 2 2 2 0 F-112 protein Mig-14 PF07395.11 EGG21752.1 - 0.041 13.3 1.6 0.084 12.2 1.0 1.7 1 1 1 2 2 2 0 Mig-14 DUF4119 PF13494.6 EGG21752.1 - 0.17 12.0 3.9 0.17 12.1 1.5 2.2 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) Complex1_LYR_2 PF13233.6 EGG21752.1 - 0.59 10.9 8.6 22 5.9 8.0 2.6 1 1 1 2 2 2 0 Complex1_LYR-like EspB PF05802.11 EGG21752.1 - 0.95 9.4 6.8 9.8 6.1 6.8 2.0 1 1 0 1 1 1 0 Enterobacterial EspB protein Med9 PF07544.13 EGG21752.1 - 5 7.3 14.6 2.9 8.1 1.2 4.1 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DUF2115 PF09888.9 EGG21752.1 - 5.2 7.6 8.9 1.9 9.0 5.0 2.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) SlyX PF04102.12 EGG21752.1 - 5.5 7.7 13.1 11 6.7 1.1 3.7 3 1 1 4 4 4 0 SlyX DUF2203 PF09969.9 EGG21752.1 - 9.8 6.9 8.3 4.4 8.1 2.3 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Pkinase PF00069.25 EGG21753.1 - 2.8e-73 246.5 0.0 3.2e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21753.1 - 1.9e-29 102.8 0.0 2.4e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG21753.1 - 0.098 12.6 0.1 0.35 10.7 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTO_CTD PF12934.7 EGG21753.1 - 0.13 12.1 0.1 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 FTO C-terminal domain TPR_12 PF13424.6 EGG21754.1 - 3.6e-71 235.5 11.5 6.4e-18 64.8 0.1 9.2 8 1 0 9 9 9 7 Tetratricopeptide repeat RasGEF PF00617.19 EGG21754.1 - 7.3e-54 182.6 5.5 7.3e-54 182.6 5.5 2.7 2 0 0 2 2 2 1 RasGEF domain TPR_10 PF13374.6 EGG21754.1 - 1.1e-37 126.9 6.5 4.5e-06 26.4 0.0 10.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGG21754.1 - 6.8e-29 97.6 32.1 0.00031 20.6 0.9 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 EGG21754.1 - 9.4e-29 98.0 42.6 1.5e-05 24.6 0.9 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.6 EGG21754.1 - 8.2e-16 56.8 12.5 0.00033 20.5 0.1 8.8 10 0 0 10 10 9 3 Tetratricopeptide repeat RasGEF_N PF00618.20 EGG21754.1 - 1e-15 57.9 2.2 1e-15 57.9 2.2 6.0 6 0 0 6 6 5 1 RasGEF N-terminal motif TPR_8 PF13181.6 EGG21754.1 - 4.6e-15 54.5 44.4 0.0078 16.4 0.9 10.4 11 0 0 11 11 10 6 Tetratricopeptide repeat DUF4062 PF13271.6 EGG21754.1 - 1.7e-14 53.9 0.1 8.5e-14 51.7 0.1 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) TPR_MalT PF17874.1 EGG21754.1 - 8.8e-12 45.0 0.2 4.8e-08 32.7 0.1 3.4 1 1 2 3 3 3 2 MalT-like TPR region TPR_19 PF14559.6 EGG21754.1 - 4.8e-08 33.4 1.9 3.1 8.4 0.0 5.9 4 2 3 7 7 7 2 Tetratricopeptide repeat BRCT_2 PF16589.5 EGG21754.1 - 5.9e-07 29.8 0.0 4e-06 27.1 0.0 2.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain TPR_11 PF13414.6 EGG21754.1 - 1.2e-06 28.1 26.4 0.69 9.6 0.1 8.8 7 2 1 8 8 8 2 TPR repeat TPR_16 PF13432.6 EGG21754.1 - 1.7e-06 28.6 0.5 3.5 8.3 0.0 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG21754.1 - 3.2e-06 27.1 5.3 0.99 9.9 0.1 7.3 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG21754.1 - 2.8e-05 24.5 0.3 56 4.9 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF2225 PF09986.9 EGG21754.1 - 0.00097 18.9 20.9 0.036 13.8 0.6 4.7 3 2 1 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2225) BRCT PF00533.26 EGG21754.1 - 0.0018 18.6 0.1 0.012 16.0 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGG21754.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain Retrotrans_gag PF03732.17 EGG21754.1 - 0.074 13.3 5.5 0.081 13.2 0.1 3.5 4 0 0 4 4 3 0 Retrotransposon gag protein MIT PF04212.18 EGG21754.1 - 0.31 11.1 13.6 3.2 7.9 0.1 5.6 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain CDC45 PF02724.14 EGG21755.1 - 0.0038 15.6 10.0 0.0095 14.3 10.0 1.6 1 0 0 1 1 1 1 CDC45-like protein Mitofilin PF09731.9 EGG21755.1 - 0.017 14.0 21.8 0.0049 15.8 16.4 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Pyr_redox_2 PF07992.14 EGG21756.1 - 3.4e-38 131.5 0.6 5.8e-38 130.8 0.6 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG21756.1 - 3.8e-17 62.6 1.0 1.6e-11 44.6 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG21756.1 - 1.3e-08 34.5 0.3 4.2e-05 23.0 0.3 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGG21756.1 - 8.2e-07 28.9 2.5 0.00015 21.5 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGG21756.1 - 4e-06 26.3 0.1 0.055 12.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGG21756.1 - 9e-06 25.8 1.2 0.0023 18.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EGG21756.1 - 5.9e-05 23.4 0.6 0.16 12.4 0.1 2.8 2 1 0 2 2 2 2 Putative NAD(P)-binding K_oxygenase PF13434.6 EGG21756.1 - 6.3e-05 22.3 0.1 0.028 13.6 0.0 2.3 1 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EGG21756.1 - 7.8e-05 21.9 0.1 0.3 10.1 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.14 EGG21756.1 - 0.0002 20.3 0.4 0.067 12.0 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase TrkA_N PF02254.18 EGG21756.1 - 0.0003 21.0 1.1 1 9.7 0.0 2.8 2 1 0 2 2 2 2 TrkA-N domain FAD_binding_2 PF00890.24 EGG21756.1 - 0.0032 16.6 3.4 0.096 11.8 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 EGG21756.1 - 0.01 14.6 0.4 2.1 6.9 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EGG21756.1 - 0.039 13.2 0.4 6.9 5.9 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1188 PF06690.11 EGG21756.1 - 0.055 13.0 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) NAD_binding_9 PF13454.6 EGG21756.1 - 0.079 12.9 2.1 2.6 8.0 0.0 3.5 5 1 0 5 5 5 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EGG21756.1 - 0.12 12.7 1.6 3.7 7.8 0.5 2.6 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain baeRF_family5 PF18846.1 EGG21756.1 - 0.12 12.6 0.1 0.37 11.0 0.1 1.8 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 Spermine_synth PF01564.17 EGG21756.1 - 0.15 11.5 0.5 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Spermine/spermidine synthase domain Ank_2 PF12796.7 EGG21757.1 - 4.2e-13 49.7 2.1 3.2e-06 27.6 0.3 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG21757.1 - 3.5e-09 36.2 5.9 0.59 10.9 0.1 7.1 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 EGG21757.1 - 3.4e-08 33.9 5.4 0.0012 19.3 0.1 5.0 3 2 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG21757.1 - 0.0072 16.6 0.1 0.62 10.5 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DnaB PF00772.21 EGG21757.1 - 0.14 12.3 1.0 0.53 10.4 0.3 2.5 2 1 0 2 2 2 0 DnaB-like helicase N terminal domain Ank_4 PF13637.6 EGG21758.1 - 8.8e-08 32.5 0.8 0.15 12.7 0.1 4.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG21758.1 - 2.4e-07 31.2 1.0 0.00021 21.8 0.3 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG21758.1 - 5.9e-07 29.3 0.7 2 9.3 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 EGG21759.1 - 5.9e-07 30.0 1.3 1e-05 26.0 0.3 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG21759.1 - 1.8e-06 28.4 0.1 0.19 12.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG21759.1 - 7.4e-05 22.9 1.6 12 6.9 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat APP_N PF02177.16 EGG21759.1 - 0.12 12.7 1.1 17 5.8 0.0 2.6 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding SR-25 PF10500.9 EGG21760.1 - 0.00017 21.3 17.5 0.00027 20.6 17.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 EGG21760.1 - 0.52 9.0 6.0 0.59 8.8 6.0 1.1 1 0 0 1 1 1 0 Presenilin GEN1_C PF18380.1 EGG21760.1 - 0.79 10.6 5.4 1.5 9.8 5.4 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain YL1 PF05764.13 EGG21760.1 - 0.97 9.5 16.6 4.7 7.3 16.7 1.8 1 1 0 1 1 1 0 YL1 nuclear protein RNA_pol_Rpc4 PF05132.14 EGG21760.1 - 3.4 8.1 13.5 12 6.3 13.5 1.8 1 1 0 1 1 1 0 RNA polymerase III RPC4 SRP72 PF08492.12 EGG21760.1 - 4.7 7.7 12.1 3.8 8.0 7.4 2.3 2 0 0 2 2 2 0 SRP72 RNA-binding domain CCDC106 PF15794.5 EGG21760.1 - 4.9 6.8 15.8 10 5.8 15.8 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4604 PF15377.6 EGG21760.1 - 7.7 6.9 20.8 11 6.3 20.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SRP-alpha_N PF04086.13 EGG21760.1 - 8 6.3 17.1 10 5.9 17.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Beta-lactamase PF00144.24 EGG21761.1 - 1e-31 110.4 0.0 2.6e-31 109.1 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase RHSP PF07999.11 EGG21762.1 - 0.045 12.6 0.1 2.5 6.8 0.0 2.4 2 1 0 2 2 2 0 Retrotransposon hot spot protein RUN PF02759.19 EGG21763.1 - 0.0007 19.6 0.4 0.0033 17.4 0.4 2.2 1 1 0 1 1 1 1 RUN domain EGF_2 PF07974.13 EGG21764.1 - 0.48 10.8 30.7 0.099 13.0 7.5 2.6 2 0 0 2 2 2 0 EGF-like domain Glyco_hydro_57 PF03065.15 EGG21765.1 - 0.02 14.1 0.1 0.085 12.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 DSPc PF00782.20 EGG21766.1 - 1.6e-32 112.1 0.1 3.2e-32 111.1 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 EGG21766.1 - 5.8e-05 23.6 0.0 0.0014 19.1 0.0 2.9 2 1 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.6 EGG21766.1 - 0.0036 17.4 0.2 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EGG21766.1 - 0.0059 16.2 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SAM_PNT PF02198.16 EGG21767.1 - 0.051 13.5 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain adh_short PF00106.25 EGG21768.1 - 1.1e-29 103.3 3.9 4.5e-28 98.0 0.1 3.0 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG21768.1 - 4.4e-18 65.7 0.9 1.8e-16 60.4 0.0 2.9 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG21768.1 - 1.4e-07 31.6 0.5 3.3e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EGG21768.1 - 1.7e-06 27.7 0.0 4.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGG21768.1 - 0.00021 20.5 0.1 0.00038 19.7 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGG21768.1 - 0.00031 20.7 0.0 0.001 19.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGG21768.1 - 0.00068 19.3 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 EGG21768.1 - 0.0032 17.5 0.3 0.013 15.6 0.3 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Baculo_LEF-11 PF06385.12 EGG21768.1 - 0.0091 16.5 1.1 0.018 15.5 0.1 2.1 2 0 0 2 2 2 1 Baculovirus LEF-11 protein F420_oxidored PF03807.17 EGG21768.1 - 0.075 13.6 1.6 0.1 13.2 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent HORMA PF02301.18 EGG21769.1 - 8.2e-15 55.0 0.1 1.9e-14 53.8 0.1 1.5 1 1 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 EGG21769.1 - 0.0082 16.0 0.7 0.056 13.3 0.6 2.2 1 1 0 1 1 1 1 Bacterial HORMA domain 2 IMPa_N_2 PF18650.1 EGG21769.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain MATH PF00917.26 EGG21770.1 - 2.8e-41 140.2 26.2 5.9e-15 55.4 1.7 4.7 5 0 0 5 5 5 4 MATH domain USP7_ICP0_bdg PF12436.8 EGG21770.1 - 8.7e-30 103.8 0.1 2.2e-29 102.5 0.1 1.7 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 ubiquitin PF00240.23 EGG21770.1 - 0.00025 20.7 0.1 0.11 12.3 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_2 PF14560.6 EGG21770.1 - 0.0014 19.1 0.0 0.16 12.4 0.0 3.0 2 0 0 2 2 2 1 Ubiquitin-like domain UN_NPL4 PF11543.8 EGG21770.1 - 0.056 13.9 0.3 1.6 9.3 0.0 3.3 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 YukD PF08817.10 EGG21770.1 - 0.15 12.7 0.0 0.37 11.5 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD UQ_con PF00179.26 EGG21771.1 - 7e-34 116.5 0.2 1.8e-26 92.4 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.22 EGG21771.1 - 6.5e-05 23.2 1.0 0.15 12.4 0.0 3.0 2 1 0 2 2 2 2 RWD domain SDA1 PF05285.12 EGG21771.1 - 0.0015 18.0 11.6 0.0029 17.1 11.6 1.4 1 0 0 1 1 1 1 SDA1 UEV PF05743.13 EGG21771.1 - 0.0038 17.1 0.2 0.04 13.8 0.0 2.8 2 1 0 2 2 2 1 UEV domain RuBisCO_small PF00101.20 EGG21771.1 - 0.0095 15.9 0.0 0.037 14.0 0.0 2.0 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase, small chain CDC45 PF02724.14 EGG21771.1 - 0.028 12.7 5.2 0.042 12.2 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 EGG21771.1 - 0.073 13.2 14.2 0.13 12.3 14.2 1.4 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 EGG21771.1 - 0.25 9.4 21.6 0.46 8.5 21.6 1.4 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EGG21771.1 - 0.25 9.5 18.4 0.013 13.7 13.0 1.5 2 0 0 2 2 2 0 Nop14-like family TRAP_alpha PF03896.16 EGG21771.1 - 6.6 5.8 10.9 12 5.0 10.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Spt5_N PF11942.8 EGG21771.1 - 8.1 7.5 20.5 18 6.4 20.5 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Cwf_Cwc_15 PF04889.12 EGG21771.1 - 8.6 6.0 19.0 19 4.9 19.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 EGG21771.1 - 9.8 4.6 12.4 19 3.6 12.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PFK PF00365.20 EGG21772.1 - 2.5e-183 607.8 1.4 7.1e-103 343.8 0.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase Inositol_P PF00459.25 EGG21774.1 - 1.5e-46 159.1 0.1 4.2e-46 157.6 0.1 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family CTP_synth_N PF06418.14 EGG21775.1 - 0.14 11.4 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 CTP synthase N-terminus Methyltr_RsmB-F PF01189.17 EGG21777.1 - 1.1e-33 116.6 0.0 3.8e-19 69.1 0.0 2.5 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 EGG21777.1 - 1.9e-07 31.0 0.0 2.7e-05 24.0 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG21777.1 - 2.6e-07 31.3 0.0 8.6e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG21777.1 - 3.6e-06 26.9 0.0 3.9e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EGG21777.1 - 1.2e-05 25.5 0.0 4.6e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EGG21777.1 - 0.00072 19.0 0.0 0.0035 16.7 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EGG21777.1 - 0.015 15.9 0.0 0.12 13.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain ArsA_ATPase PF02374.15 EGG21777.1 - 0.033 13.4 0.2 0.033 13.4 0.2 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase MTS PF05175.14 EGG21777.1 - 0.039 13.5 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Methyltr_RsmF_N PF17125.5 EGG21777.1 - 0.041 14.4 0.1 0.11 13.0 0.1 1.7 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF FtsX_ECD PF18075.1 EGG21777.1 - 0.043 14.4 0.8 0.043 14.4 0.8 2.5 3 0 0 3 3 2 0 FtsX extracellular domain PCMT PF01135.19 EGG21777.1 - 0.089 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EGG21777.1 - 0.8 10.5 0.0 0.8 10.5 0.0 3.5 3 1 1 4 4 4 0 Methyltransferase domain Tim54 PF11711.8 EGG21777.1 - 1.2 7.9 8.1 0.28 9.9 2.1 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Myc_N PF01056.18 EGG21777.1 - 1.5 8.6 11.4 0.22 11.4 0.8 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Pox_Ag35 PF03286.14 EGG21777.1 - 1.7 8.4 16.4 0.11 12.3 3.5 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Sec62 PF03839.16 EGG21780.1 - 2.1 7.8 3.7 2.7 7.4 3.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 TMEM171 PF15471.6 EGG21780.1 - 2.3 7.1 7.3 2.9 6.8 7.3 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 IF4E PF01652.18 EGG21781.1 - 1.1e-27 96.8 3.1 4.6e-27 94.8 3.1 2.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pex14_N PF04695.13 EGG21782.1 - 0.0016 19.1 0.8 0.0035 18.0 0.8 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Cyclin PF08613.11 EGG21782.1 - 0.0035 17.7 0.5 0.0077 16.6 0.5 1.6 1 0 0 1 1 1 1 Cyclin DUF1635 PF07795.11 EGG21782.1 - 0.0063 16.4 2.9 0.0063 16.4 2.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1635) Suf PF05843.14 EGG21782.1 - 0.11 12.5 1.2 0.18 11.8 1.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Alpha_GJ PF03229.13 EGG21782.1 - 0.14 12.8 0.1 0.27 11.8 0.1 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J Zn_peptidase PF04228.13 EGG21782.1 - 0.22 10.9 1.9 8.9 5.7 0.3 2.3 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase DUF2615 PF11027.8 EGG21782.1 - 1.5 9.0 4.1 23 5.2 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) Fucokinase PF07959.12 EGG21783.1 - 3.8e-32 111.7 0.2 8.5e-31 107.3 0.2 2.7 1 1 0 1 1 1 1 L-fucokinase HIG_1_N PF04588.13 EGG21783.1 - 9.2e-11 41.8 0.1 2.5e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region GHMP_kinases_N PF00288.26 EGG21783.1 - 9.4e-07 29.0 0.5 9.4e-07 29.0 0.5 2.8 3 0 0 3 3 3 1 GHMP kinases N terminal domain Pex14_N PF04695.13 EGG21783.1 - 5.4 7.7 8.5 0.1 13.2 0.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DJ-1_PfpI PF01965.24 EGG21784.1 - 3.2e-45 153.9 0.0 3.6e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family LsmAD PF06741.13 EGG21785.1 - 1.6e-26 92.6 3.9 1.6e-26 92.6 3.9 2.3 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 EGG21785.1 - 2.2e-16 59.8 0.0 6.5e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.15 EGG21785.1 - 1.4e-05 24.4 3.9 0.0024 17.4 0.4 2.8 1 1 1 2 2 2 2 Ataxin-2 C-terminal region ROF PF07073.12 EGG21785.1 - 0.2 11.8 0.0 0.66 10.2 0.0 1.8 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) Glyco_transf_10 PF00852.19 EGG21786.1 - 8.9e-31 107.0 2.5 9.6e-31 106.9 1.3 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Laminin_G_3 PF13385.6 EGG21786.1 - 5.7e-16 59.0 0.0 1e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Glyco_tran_10_N PF17039.5 EGG21786.1 - 9.7e-09 35.7 0.4 2.5e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal CMS1 PF14617.6 EGG21786.1 - 0.035 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit FANCM-MHF_bd PF16783.5 EGG21786.1 - 0.14 12.2 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 FANCM to MHF binding domain Pkinase PF00069.25 EGG21787.1 - 4.1e-42 144.4 0.1 1.6e-41 142.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21787.1 - 1.6e-26 93.2 0.0 1e-25 90.5 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 EGG21787.1 - 6.1e-13 49.1 0.3 2.4e-12 47.1 0.3 2.1 1 0 0 1 1 1 1 Ribonuclease 2-5A RIO1 PF01163.22 EGG21787.1 - 0.003 17.2 0.1 0.0095 15.5 0.1 1.8 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGG21787.1 - 0.0052 16.2 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG21787.1 - 0.0085 16.0 0.3 0.038 13.9 0.3 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1387 PF07139.11 EGG21787.1 - 0.38 10.5 34.8 0.95 9.1 34.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SOG2 PF10428.9 EGG21787.1 - 5.7 6.0 35.5 9 5.4 35.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein WW PF00397.26 EGG21788.1 - 2.3e-12 46.8 1.5 1e-11 44.7 0.3 2.8 2 0 0 2 2 2 1 WW domain C2 PF00168.30 EGG21788.1 - 9.4e-11 41.9 1.1 3.1e-10 40.2 0.3 2.1 2 0 0 2 2 2 1 C2 domain PRK PF00485.18 EGG21789.1 - 2e-47 161.5 0.1 3.3e-47 160.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family TPT PF03151.16 EGG21789.1 - 2e-28 99.6 26.4 3.2e-28 98.9 26.4 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGG21789.1 - 4.2e-08 33.5 40.0 0.00067 19.8 18.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family AAA_18 PF13238.6 EGG21789.1 - 4.7e-06 27.2 1.5 7.4e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EGG21789.1 - 0.0022 17.8 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase T2SSE PF00437.20 EGG21789.1 - 0.0046 16.1 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.6 EGG21789.1 - 0.01 16.3 0.2 2 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGG21789.1 - 0.013 14.8 0.0 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.14 EGG21789.1 - 0.025 14.5 0.0 0.15 12.0 0.0 2.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 EGG21789.1 - 0.068 13.1 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF2207 PF09972.9 EGG21789.1 - 0.12 11.1 0.0 0.12 11.1 0.0 3.7 2 1 1 3 3 2 0 Predicted membrane protein (DUF2207) ATP_bind_1 PF03029.17 EGG21789.1 - 0.13 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CoaE PF01121.20 EGG21789.1 - 0.14 11.9 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_22 PF13401.6 EGG21789.1 - 0.16 12.3 0.0 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain 7TMR-DISM_7TM PF07695.11 EGG21789.1 - 5.8 6.8 36.9 4.8 7.0 10.4 2.7 2 0 0 2 2 2 0 7TM diverse intracellular signalling Occludin_ELL PF07303.13 EGG21791.1 - 2.2e-06 28.3 10.2 5.1e-06 27.1 10.2 1.6 1 0 0 1 1 1 1 Occludin homology domain Acyltransferase PF01553.21 EGG21792.1 - 8.2e-13 48.1 0.1 1.9e-12 47.0 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase EF1_GNE PF00736.19 EGG21793.1 - 9.4e-35 118.7 0.3 1.8e-34 117.7 0.3 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EGG21793.1 - 0.00022 21.6 8.3 0.00078 19.8 8.3 2.0 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region Vac_ImportDeg PF09783.9 EGG21794.1 - 6.7e-57 191.8 0.2 1.1e-56 191.2 0.2 1.3 1 0 0 1 1 1 1 Vacuolar import and degradation protein MFS_1 PF07690.16 EGG21795.1 - 6.8e-20 71.3 39.9 2.7e-19 69.3 36.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pentapeptide PF00805.22 EGG21796.1 - 2.6e-30 103.6 17.9 1.4e-08 34.2 0.5 4.3 1 1 3 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EGG21796.1 - 1.1e-19 70.3 0.4 3.3e-10 40.0 0.1 2.9 1 1 2 3 3 3 2 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 EGG21796.1 - 5.8e-15 55.4 0.0 1.2e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.6 EGG21796.1 - 1.5e-10 41.0 0.0 0.0012 19.0 0.0 2.9 2 1 0 2 2 2 2 Pentapeptide repeats (9 copies) CfAFP PF05264.11 EGG21796.1 - 1.1 9.3 6.1 9.9 6.1 0.1 2.9 2 1 1 3 3 3 0 Choristoneura fumiferana antifreeze protein (CfAFP) Ribosomal_S18 PF01084.20 EGG21798.1 - 3e-13 49.7 0.0 7e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 DUF382 PF04037.13 EGG21801.1 - 7.8e-12 45.5 0.1 7.8e-12 45.5 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF382) SR-25 PF10500.9 EGG21801.1 - 0.0022 17.7 7.9 0.0022 17.7 7.9 4.1 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein NUC153 PF08159.12 EGG21801.1 - 0.014 15.2 0.4 0.032 14.1 0.4 1.6 1 0 0 1 1 1 0 NUC153 domain RPN7 PF10602.9 EGG21802.1 - 4.1e-47 160.1 5.5 1.9e-46 157.9 2.1 3.2 2 1 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EGG21802.1 - 3.5e-14 53.2 2.6 5e-14 52.7 0.5 2.4 2 1 0 2 2 2 1 PCI domain TPR_1 PF00515.28 EGG21802.1 - 0.0065 16.2 0.3 0.02 14.7 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG21802.1 - 0.0075 16.3 3.7 0.0086 16.1 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG21802.1 - 0.02 15.1 0.1 0.044 14.1 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Apolipo_F PF15148.6 EGG21802.1 - 0.047 13.2 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein F TPR_7 PF13176.6 EGG21802.1 - 0.11 12.6 0.1 0.45 10.7 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DDRGK PF09756.9 EGG21802.1 - 1.1 8.8 4.7 0.5 9.9 0.1 2.5 4 0 0 4 4 4 0 DDRGK domain Sugarporin_N PF11471.8 EGG21803.1 - 0.00097 19.0 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension ABC_tran_CTD PF16326.5 EGG21803.1 - 0.0013 19.0 0.1 0.0022 18.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter C-terminal domain RNA_pol_Rpc34 PF05158.12 EGG21804.1 - 8.4e-54 183.2 2.1 1.3e-39 136.6 1.6 2.0 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 EGG21804.1 - 2.4e-06 27.6 1.7 0.00056 20.0 0.2 2.7 3 0 0 3 3 3 2 B-block binding subunit of TFIIIC Penicillinase_R PF03965.16 EGG21804.1 - 0.00071 19.9 0.4 0.21 12.0 0.0 3.1 3 0 0 3 3 3 1 Penicillinase repressor MarR PF01047.22 EGG21804.1 - 0.00079 19.3 0.2 0.15 12.0 0.0 2.9 3 0 0 3 3 3 1 MarR family TFIIE_alpha PF02002.17 EGG21804.1 - 0.0019 18.0 2.2 0.73 9.7 0.3 3.1 2 1 1 3 3 3 2 TFIIE alpha subunit RPA_C PF08784.11 EGG21804.1 - 0.013 16.2 1.9 8.1 7.2 0.1 3.2 1 1 2 3 3 3 0 Replication protein A C terminal HTH_27 PF13463.6 EGG21804.1 - 0.031 14.8 0.6 3.8 8.1 0.1 3.3 3 1 0 3 3 3 0 Winged helix DNA-binding domain MarR_2 PF12802.7 EGG21804.1 - 0.035 14.0 0.0 4.6 7.2 0.0 2.9 3 0 0 3 3 3 0 MarR family RibD_C PF01872.17 EGG21804.1 - 0.035 13.9 0.1 0.073 12.9 0.0 1.5 2 0 0 2 2 2 0 RibD C-terminal domain DUF2250 PF10007.9 EGG21804.1 - 0.22 11.7 1.7 4.3 7.5 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DUF4479 PF14794.6 EGG21804.1 - 0.3 11.0 2.0 1.1 9.1 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4479) EMP24_GP25L PF01105.24 EGG21805.1 - 8.8e-51 172.4 0.1 1.2e-50 172.0 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ni_hydr_CYTB PF01292.20 EGG21805.1 - 0.046 13.3 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Spem1 PF15670.5 EGG21806.1 - 0.009 15.6 0.0 0.011 15.4 0.0 1.0 1 0 0 1 1 1 1 Spermatid maturation protein 1 MbtH PF03621.13 EGG21807.1 - 0.073 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 MbtH-like protein Response_reg PF00072.24 EGG21808.1 - 5.5e-42 142.5 0.4 7.1e-28 97.0 0.3 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 EGG21808.1 - 3.9e-30 104.6 0.5 1.4e-29 102.8 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 EGG21808.1 - 6.8e-23 80.8 0.1 3.5e-06 27.3 0.1 6.1 5 0 0 5 5 5 4 HAMP domain HisKA PF00512.25 EGG21808.1 - 1.4e-19 69.9 1.2 8e-19 67.5 0.0 3.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain SpoIIID PF12116.8 EGG21808.1 - 0.00025 21.1 0.0 4 7.6 0.0 4.0 3 0 0 3 3 3 1 Stage III sporulation protein D WXG100 PF06013.12 EGG21808.1 - 0.0037 17.5 0.8 19 5.6 0.0 4.8 3 1 1 4 4 4 0 Proteins of 100 residues with WXG GLE1 PF07817.13 EGG21808.1 - 0.081 12.1 0.7 2.6 7.2 0.0 3.1 2 1 1 3 3 3 0 GLE1-like protein DUF948 PF06103.11 EGG21808.1 - 0.13 12.5 26.5 0.28 11.5 1.5 6.2 3 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) Focal_AT PF03623.13 EGG21808.1 - 0.45 10.5 3.3 37 4.3 0.0 4.2 2 1 0 4 4 4 0 Focal adhesion targeting region DUF3829 PF12889.7 EGG21808.1 - 1.1 8.6 5.5 17 4.7 0.0 4.1 3 2 2 5 5 5 0 Protein of unknown function (DUF3829) REF PF05755.12 EGG21808.1 - 1.4 8.7 4.0 15 5.3 0.3 3.4 2 1 2 4 4 4 0 Rubber elongation factor protein (REF) Syntaxin_2 PF14523.6 EGG21808.1 - 1.4 9.3 10.6 5.9 7.3 0.3 5.4 5 2 1 6 6 5 0 Syntaxin-like protein LSM PF01423.22 EGG21810.1 - 9.2e-19 66.9 2.2 1.4e-18 66.4 2.2 1.3 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 EGG21810.1 - 0.019 14.9 1.0 0.035 14.0 0.4 1.8 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain FAD_binding_3 PF01494.19 EGG21811.1 - 1.1e-47 163.0 0.0 3.2e-46 158.2 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGG21811.1 - 0.0068 15.7 0.1 0.023 14.0 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGG21811.1 - 0.0095 15.0 0.0 0.03 13.4 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein TrkA_N PF02254.18 EGG21811.1 - 0.018 15.3 0.3 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain ThiF PF00899.21 EGG21811.1 - 0.031 13.6 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.14 EGG21811.1 - 0.066 12.1 0.0 0.14 11.0 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 EGG21811.1 - 0.076 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 EGG21811.1 - 0.078 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGG21811.1 - 0.17 12.5 0.1 0.62 10.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SF1-HH PF16275.5 EGG21812.1 - 2.6e-37 127.6 1.4 2.6e-37 127.6 1.4 2.7 2 1 1 3 3 3 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 EGG21812.1 - 6.9e-08 32.2 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 KH domain Suf PF05843.14 EGG21812.1 - 7 6.5 20.5 1.4 8.8 15.2 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF2053 PF09767.9 EGG21813.1 - 4.7e-39 134.1 8.5 7.9e-39 133.4 8.5 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) Pkinase_Tyr PF07714.17 EGG21814.1 - 6.9e-70 235.3 0.0 1.1e-69 234.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG21814.1 - 1.1e-64 218.4 0.0 2.6e-64 217.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EGG21814.1 - 0.00052 19.4 0.0 0.0038 16.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGG21814.1 - 0.025 13.9 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMA7 PF09072.10 EGG21814.1 - 0.52 11.2 3.9 19 6.2 0.6 2.7 2 0 0 2 2 2 0 Translation machinery associated TMA7 CBM49 PF09478.10 EGG21815.1 - 0.03 14.6 0.2 0.07 13.5 0.2 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 Thioredoxin PF00085.20 EGG21817.1 - 3.6e-22 78.3 0.0 1.2e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EGG21817.1 - 2.1e-05 24.9 0.1 7.1e-05 23.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EGG21817.1 - 0.0035 17.2 0.2 0.013 15.4 0.0 2.0 2 1 0 2 2 2 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 EGG21817.1 - 0.0037 17.2 0.2 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 AhpC/TSA family OST3_OST6 PF04756.13 EGG21817.1 - 0.0046 16.3 0.4 0.39 10.0 0.0 2.4 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EGG21817.1 - 0.016 15.5 0.3 13 6.2 0.0 3.2 2 2 1 3 3 3 0 Thioredoxin-like Glutaredoxin PF00462.24 EGG21817.1 - 0.11 12.7 0.2 2.2 8.6 0.1 2.5 3 0 0 3 3 3 0 Glutaredoxin DPBB_1 PF03330.18 EGG21819.1 - 5.9e-07 29.7 0.3 1.1e-05 25.7 0.3 2.5 1 1 0 1 1 1 1 Lytic transglycolase Mu-like_Com PF10122.9 EGG21819.1 - 0.069 12.6 0.1 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com Cerato-platanin PF07249.12 EGG21819.1 - 0.084 13.0 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Cerato-platanin Ras PF00071.22 EGG21820.1 - 6.3e-51 172.2 0.0 1.4e-50 171.0 0.0 1.7 1 0 0 1 1 1 1 Ras family Peptidase_S13 PF02113.15 EGG21820.1 - 2.4e-34 118.8 0.0 4.3e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family TTL PF03133.15 EGG21820.1 - 2.9e-34 118.6 12.4 2.9e-19 69.3 0.6 4.0 2 1 1 3 3 2 2 Tubulin-tyrosine ligase family Roc PF08477.13 EGG21820.1 - 7.3e-21 74.6 0.0 2.4e-20 72.9 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FNIP PF05725.12 EGG21820.1 - 1e-13 51.2 25.8 0.0092 16.1 0.2 9.5 10 1 0 11 11 11 5 FNIP Repeat Arf PF00025.21 EGG21820.1 - 2.5e-06 27.0 0.0 5.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Fz PF01392.22 EGG21820.1 - 2.7e-05 24.8 9.9 2.7e-05 24.8 9.9 2.8 2 0 0 2 2 2 1 Fz domain ATPgrasp_ST PF14397.6 EGG21820.1 - 0.00042 19.7 0.2 0.011 15.0 0.0 2.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 EGG21820.1 - 0.0065 15.7 1.2 0.44 9.7 0.0 2.7 3 0 0 3 3 3 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 EGG21820.1 - 0.058 12.9 0.1 13 5.2 0.1 2.6 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Beta-lactamase2 PF13354.6 EGG21820.1 - 0.1 12.2 0.0 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase enzyme family Metallophos PF00149.28 EGG21821.1 - 1.8e-12 48.2 1.6 2.5e-12 47.8 1.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG21821.1 - 3.7e-12 46.7 2.2 3e-11 43.8 2.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EGG21821.1 - 1.9e-08 34.0 0.1 0.0074 15.6 0.0 2.9 2 1 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily LRR_6 PF13516.6 EGG21822.1 - 8.5e-08 31.7 6.1 0.041 14.0 0.0 5.6 5 0 0 5 5 5 2 Leucine Rich repeat F-box-like PF12937.7 EGG21822.1 - 0.094 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like TFIIA PF03153.13 EGG21822.1 - 0.25 11.3 19.2 1.5 8.8 4.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Menin PF05053.13 EGG21822.1 - 0.83 7.9 14.0 0.04 12.3 3.9 2.1 2 0 0 2 2 2 0 Menin CobT PF06213.12 EGG21822.1 - 9.3 5.6 16.1 20 4.5 16.1 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Seipin PF06775.14 EGG21824.1 - 1.1e-50 172.6 3.0 2.4e-50 171.4 3.0 1.5 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF2681 PF10883.8 EGG21824.1 - 0.00028 21.2 0.9 0.00028 21.2 0.9 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2681) DUF4199 PF13858.6 EGG21824.1 - 0.015 15.7 0.5 0.015 15.7 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) LRR19-TM PF15176.6 EGG21824.1 - 0.044 13.8 0.1 0.044 13.8 0.1 4.1 5 0 0 5 5 5 0 Leucine-rich repeat family 19 TM domain COX14 PF14880.6 EGG21824.1 - 0.14 12.0 0.0 4 7.3 0.0 2.7 2 0 0 2 2 2 0 Cytochrome oxidase c assembly FAD_binding_3 PF01494.19 EGG21825.1 - 2e-50 172.0 0.0 3.3e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGG21825.1 - 0.049 12.9 0.0 0.17 11.1 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGG21825.1 - 0.07 11.8 0.1 0.89 8.2 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Staphylcoagulse PF04022.12 EGG21825.1 - 0.077 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Staphylocoagulase repeat NAD_binding_8 PF13450.6 EGG21825.1 - 0.16 12.3 0.0 0.57 10.5 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ODV-E18 PF10717.9 EGG21825.1 - 0.76 9.7 5.8 0.13 12.2 0.3 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Mob1_phocein PF03637.17 EGG21826.1 - 1.4e-41 142.3 0.0 1.2e-35 123.0 0.0 2.1 1 1 1 2 2 2 2 Mob1/phocein family PP_kinase_C PF13090.6 EGG21828.1 - 7.4e-65 217.6 0.0 1.4e-64 216.7 0.0 1.5 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain 2 PP_kinase PF02503.17 EGG21828.1 - 1.1e-63 214.5 0.8 2e-63 213.7 0.8 1.4 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_C_1 PF17941.1 EGG21828.1 - 8.4e-60 201.1 0.2 4.4e-59 198.8 0.0 2.1 1 1 1 2 2 2 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_N PF13089.6 EGG21828.1 - 9.7e-20 70.9 0.5 9.7e-20 70.9 0.5 2.2 2 0 0 2 2 2 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 EGG21828.1 - 3e-07 30.4 0.0 0.007 16.3 0.0 3.1 2 1 0 2 2 2 2 PLD-like domain CTK3 PF12243.8 EGG21828.1 - 0.038 14.0 0.6 0.36 10.9 0.0 2.9 4 0 0 4 4 4 0 CTD kinase subunit gamma CTK3 RR_TM4-6 PF06459.12 EGG21828.1 - 0.56 10.0 17.4 1 9.1 17.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DcpS_C PF11969.8 EGG21829.1 - 1.5e-27 96.3 5.5 1.6e-27 96.3 3.4 2.1 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EGG21829.1 - 1.3e-13 51.5 1.4 2.2e-13 50.8 0.6 1.9 2 0 0 2 2 2 1 HIT domain zf-C2HE PF16278.5 EGG21829.1 - 6.3e-08 32.9 1.1 2.2e-07 31.2 1.1 2.0 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger FHA_2 PF17913.1 EGG21829.1 - 3e-07 30.6 0.2 1e-06 28.8 0.1 2.0 2 0 0 2 2 2 1 FHA domain zf-H2C2_2 PF13465.6 EGG21829.1 - 0.026 14.9 0.2 0.071 13.6 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger double domain Nsp1_C PF05064.13 EGG21831.1 - 0.008 16.0 9.0 0.008 16.0 9.0 10.3 1 1 8 11 11 11 2 Nsp1-like C-terminal region Ribonuc_L-PSP PF01042.21 EGG21831.1 - 0.59 10.2 5.8 0.58 10.2 1.3 3.5 2 1 1 3 3 3 0 Endoribonuclease L-PSP VIT PF08487.10 EGG21832.1 - 1.4e-28 99.3 0.0 4.1e-28 97.8 0.0 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EGG21832.1 - 3.4e-28 98.5 0.0 7.5e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EGG21832.1 - 4.7e-13 49.7 0.0 1.3e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGG21832.1 - 3.4e-11 43.7 0.0 1.1e-10 42.2 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EGG21832.1 - 2.2e-06 27.5 0.1 5.2e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.9 EGG21832.1 - 0.0064 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.14 EGG21832.1 - 0.019 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein CobT_C PF11775.8 EGG21832.1 - 0.037 13.7 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain SR-25 PF10500.9 EGG21832.1 - 6.3 6.3 19.2 0.27 10.8 8.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MFS_1 PF07690.16 EGG21833.1 - 4.1e-12 45.7 12.4 4.1e-12 45.7 12.4 3.7 1 1 3 4 4 4 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGG21833.1 - 0.0002 20.3 3.0 0.0002 20.3 3.0 2.1 2 1 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.24 EGG21833.1 - 0.0034 16.3 8.6 0.0053 15.7 8.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4484 PF14831.6 EGG21833.1 - 0.11 12.6 5.4 0.19 11.8 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Ank_2 PF12796.7 EGG21834.1 - 2.3e-27 95.4 1.6 4.9e-10 39.9 0.1 5.2 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG21834.1 - 5e-21 74.8 4.5 2.3e-06 28.0 0.1 6.7 5 1 0 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG21834.1 - 3e-20 72.0 8.7 0.012 15.9 0.0 8.3 5 1 4 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG21834.1 - 2e-13 49.2 4.4 1.2 9.9 0.0 8.6 8 1 1 9 9 9 4 Ankyrin repeat Ank PF00023.30 EGG21834.1 - 4e-06 27.0 2.3 0.5 10.9 0.0 6.0 4 2 1 5 5 5 1 Ankyrin repeat Clathrin PF00637.20 EGG21834.1 - 0.0034 17.3 0.4 0.012 15.5 0.1 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS Ank_5 PF13857.6 EGG21835.1 - 2.6e-09 37.2 0.1 0.0053 17.0 0.0 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG21835.1 - 2.1e-07 31.4 0.4 0.0086 16.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG21835.1 - 2.5e-06 27.9 0.3 0.0003 21.3 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG21835.1 - 0.00041 20.6 0.1 2.3 9.0 0.0 4.3 4 1 1 5 5 5 1 Ankyrin repeat DUF5049 PF16468.5 EGG21835.1 - 0.0017 18.2 0.1 1.6 8.7 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF5049) Cpn60_TCP1 PF00118.24 EGG21837.1 - 8.3e-78 262.2 3.9 2.1e-48 165.2 0.7 3.0 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family zf-RING_2 PF13639.6 EGG21838.1 - 4.7e-11 42.8 13.0 7e-11 42.3 13.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGG21838.1 - 6.7e-07 28.9 10.6 1.4e-06 28.0 10.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EGG21838.1 - 6.6e-06 26.3 12.1 1.4e-05 25.3 12.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGG21838.1 - 2.4e-05 24.1 13.8 3.9e-05 23.4 13.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG21838.1 - 0.00016 21.4 14.3 0.00029 20.6 14.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGG21838.1 - 0.0002 21.3 3.3 0.00033 20.6 3.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGG21838.1 - 0.0018 18.3 7.3 0.0018 18.3 7.3 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG21838.1 - 0.0019 18.1 12.3 0.0031 17.4 12.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGG21838.1 - 0.0024 17.7 8.9 0.004 17.0 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cys_rich_CPXG PF14255.6 EGG21838.1 - 0.0062 16.4 5.1 0.045 13.6 1.9 2.6 2 0 0 2 2 2 1 Cysteine-rich CPXCG Zn_ribbon_17 PF17120.5 EGG21838.1 - 0.027 14.1 8.4 0.046 13.3 8.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 EGG21838.1 - 0.031 14.4 6.7 0.057 13.6 6.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 EptA_B_N PF08019.12 EGG21839.1 - 0.046 13.6 0.4 0.06 13.2 0.4 1.2 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB GSH_synth_ATP PF03917.17 EGG21840.1 - 4e-128 427.4 0.4 4.5e-128 427.2 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EGG21840.1 - 9.9e-33 112.7 1.7 5.3e-32 110.3 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic glutathione synthase DUF5126 PF17166.4 EGG21840.1 - 0.073 12.9 0.2 0.21 11.4 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) DUF953 PF06110.11 EGG21840.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 EGG21841.1 - 5.5e-20 71.3 0.0 6.6e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EGG21841.1 - 0.00069 19.7 0.0 0.0009 19.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EGG21841.1 - 0.002 18.4 0.0 0.0026 18.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EGG21841.1 - 0.0026 17.5 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EGG21841.1 - 0.0091 15.9 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EGG21841.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 EGG21841.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_2 PF13098.6 EGG21841.1 - 0.02 15.3 0.1 0.027 14.9 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.24 EGG21841.1 - 0.033 14.4 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin SepSecS PF05889.13 EGG21842.1 - 1.3e-121 405.9 0.0 1.2e-120 402.8 0.0 1.9 1 1 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 EGG21842.1 - 0.00014 21.3 0.0 0.00018 20.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 EGG21842.1 - 0.0045 15.8 0.0 0.0067 15.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain FNIP PF05725.12 EGG21843.1 - 0.0029 17.7 10.1 0.0095 16.1 0.1 4.4 4 0 0 4 4 4 1 FNIP Repeat DUF3446 PF11928.8 EGG21843.1 - 0.064 13.6 11.4 0.2 11.9 1.7 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain TBCC_N PF16752.5 EGG21843.1 - 0.085 13.3 4.8 0.32 11.4 4.8 2.0 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain DUF2969 PF11184.8 EGG21843.1 - 1.5 9.3 6.7 0.5 10.8 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2969) SR-25 PF10500.9 EGG21843.1 - 2.3 7.8 16.0 0.35 10.4 2.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein His_Phos_2 PF00328.22 EGG21844.1 - 5.2e-19 68.8 0.0 2.3e-16 60.1 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3446 PF11928.8 EGG21844.1 - 3.9 7.8 23.7 0.41 11.0 18.2 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Myb_DNA-binding PF00249.31 EGG21845.1 - 2.4e-33 114.1 12.7 2.9e-14 53.0 0.9 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG21845.1 - 1.4e-26 92.5 7.9 4.8e-14 52.3 0.2 3.8 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGG21845.1 - 0.00079 19.8 10.6 0.01 16.2 0.6 3.4 2 1 0 2 2 2 2 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 EGG21845.1 - 0.002 18.1 3.3 0.87 9.6 0.1 3.2 3 1 0 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 EGG21845.1 - 0.0088 16.2 0.4 4.6 7.5 0.0 2.8 2 1 0 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 EGG21845.1 - 0.031 14.4 3.1 3.6 7.7 0.5 3.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Tsg PF04668.12 EGG21845.1 - 4.3 8.0 6.3 2.2 9.0 0.1 2.9 2 1 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region TFIIA PF03153.13 EGG21845.1 - 9.3 6.1 19.2 17 5.2 19.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CTNNBL PF08216.11 EGG21846.1 - 3.1e-35 120.5 1.0 3.1e-35 120.5 1.0 3.5 2 2 1 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear s48_45 PF07422.13 EGG21846.1 - 0.14 12.7 0.1 0.14 12.7 0.1 3.0 2 1 0 2 2 2 0 Sexual stage antigen s48/45 domain PilZ_2 PF16823.5 EGG21846.1 - 0.19 11.9 0.2 0.43 10.8 0.2 1.5 1 0 0 1 1 1 0 Atypical PilZ domain, cyclic di-GMP receptor Maelstrom PF13017.6 EGG21846.1 - 0.29 10.8 4.5 6.4 6.4 4.3 2.7 1 1 0 1 1 1 0 piRNA pathway germ-plasm component FRB_dom PF08771.11 EGG21846.1 - 0.63 10.5 7.8 0.42 11.1 1.8 3.0 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain UCH PF00443.29 EGG21846.1 - 0.84 9.1 16.0 0.11 12.0 1.7 2.4 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase YqeY PF09424.10 EGG21846.1 - 1.1 9.3 9.8 0.034 14.2 2.3 2.4 2 1 1 3 3 3 0 Yqey-like protein TFIIA PF03153.13 EGG21847.1 - 4.8 7.1 25.1 6.2 6.7 25.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Abhydrolase_1 PF00561.20 EGG21848.1 - 1.3e-20 74.2 0.2 3.4e-18 66.2 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG21848.1 - 2.1e-18 66.5 0.0 5.5e-18 65.1 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGG21848.1 - 5.3e-17 63.1 0.0 7.1e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EGG21848.1 - 8.5e-05 22.8 0.2 0.00025 21.2 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Ndr PF03096.14 EGG21848.1 - 0.00013 20.8 0.0 0.00026 19.8 0.0 1.6 2 0 0 2 2 2 1 Ndr family DLH PF01738.18 EGG21848.1 - 0.00015 21.4 0.0 0.33 10.5 0.0 3.2 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EGG21848.1 - 0.0072 16.2 0.1 0.23 11.2 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 EGG21848.1 - 0.0083 15.9 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGG21848.1 - 0.035 13.8 0.1 0.087 12.5 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Esterase PF00756.20 EGG21848.1 - 0.077 12.6 1.4 0.34 10.5 0.0 2.5 2 1 1 3 3 3 0 Putative esterase DUF2048 PF09752.9 EGG21848.1 - 0.21 10.7 1.0 1.2 8.1 0.0 2.4 2 1 0 2 2 2 0 Abhydrolase domain containing 18 LIDHydrolase PF10230.9 EGG21848.1 - 0.21 11.1 1.6 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF4407 PF14362.6 EGG21849.1 - 0.22 10.8 3.5 0.24 10.7 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1387 PF07139.11 EGG21849.1 - 2 8.1 13.4 2.8 7.6 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Mucin PF01456.17 EGG21849.1 - 4.7 7.2 17.9 8 6.4 17.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Hist_deacetyl PF00850.19 EGG21850.1 - 1.6e-09 37.7 0.1 3.6e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 Histone deacetylase domain Takusan PF04822.13 EGG21850.1 - 0.0043 16.9 1.0 0.0043 16.9 1.0 2.3 2 0 0 2 2 2 1 Takusan DUF2381 PF09544.10 EGG21850.1 - 0.13 11.8 6.8 0.011 15.3 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2381) GvpG PF05120.12 EGG21850.1 - 0.33 11.0 2.3 0.84 9.7 2.3 1.7 1 0 0 1 1 1 0 Gas vesicle protein G DUF16 PF01519.16 EGG21850.1 - 1.9 9.1 9.5 7.9 7.0 2.8 2.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 APG6_N PF17675.1 EGG21850.1 - 8.7 6.9 17.2 0.46 11.0 10.3 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region IFT20 PF14931.6 EGG21850.1 - 9.4 6.4 11.3 2.3 8.4 5.1 2.8 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 EamA PF00892.20 EGG21851.1 - 2.9e-12 46.9 35.4 5.5e-07 29.8 2.6 3.0 3 0 0 3 3 3 2 EamA-like transporter family DUF2371 PF10177.9 EGG21851.1 - 0.002 18.3 0.1 0.48 10.6 0.0 2.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2371) Connexin PF00029.19 EGG21851.1 - 0.0049 16.7 1.9 0.44 10.3 0.3 2.4 2 0 0 2 2 2 1 Connexin IlvGEDA_leader PF08046.11 EGG21851.1 - 0.046 13.2 0.2 0.11 12.0 0.2 1.6 1 0 0 1 1 1 0 IlvGEDA operon leader peptide SelK_SelG PF10961.8 EGG21851.1 - 0.05 14.2 0.2 0.21 12.2 0.1 2.2 2 0 0 2 2 1 0 Selenoprotein SelK_SelG EOS1 PF12326.8 EGG21851.1 - 0.057 13.3 0.0 1.1 9.2 0.0 2.5 2 1 0 2 2 2 0 N-glycosylation protein RseC_MucC PF04246.12 EGG21851.1 - 0.071 13.1 4.7 14 5.6 0.2 3.9 4 1 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC G0-G1_switch_2 PF15103.6 EGG21851.1 - 0.11 12.9 3.4 17 5.9 0.0 3.6 3 0 0 3 3 3 0 G0/G1 switch protein 2 Tom5 PF10642.9 EGG21851.1 - 0.15 12.1 0.0 0.48 10.5 0.0 1.9 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase DUF2956 PF11169.8 EGG21851.1 - 0.3 11.3 7.2 7.6 6.8 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF2370 PF10176.9 EGG21851.1 - 1.3 8.7 3.7 9 5.9 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) PTPRCAP PF15713.5 EGG21851.1 - 1.5 9.1 16.7 0.12 12.7 6.9 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF572 PF04502.13 EGG21851.1 - 2.6 7.6 11.9 0.56 9.8 3.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4064 PF13273.6 EGG21851.1 - 4.4 7.7 18.7 0.24 11.7 1.3 5.0 3 1 2 5 5 5 0 Protein of unknown function (DUF4064) EF-hand_1 PF00036.32 EGG21852.1 - 2.7e-23 79.7 7.8 1.6e-08 33.5 0.1 5.2 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 EGG21852.1 - 1.4e-18 67.0 0.9 7.5e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGG21852.1 - 1.7e-17 61.8 6.7 4.6e-08 32.4 0.1 5.8 6 1 1 7 7 7 3 EF-hand domain EF-hand_8 PF13833.6 EGG21852.1 - 2.6e-10 40.0 6.8 0.02 14.8 0.1 5.6 2 1 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 EGG21852.1 - 5.9e-10 38.2 9.1 6.1e-08 31.8 0.2 4.6 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.6 EGG21852.1 - 4.6e-07 30.1 0.1 0.00097 19.4 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 EGG21852.1 - 0.0041 17.4 0.4 0.53 10.7 0.0 2.9 2 1 0 2 2 2 1 EF-hand domain PBS_linker_poly PF00427.21 EGG21852.1 - 0.042 13.9 0.1 0.24 11.4 0.1 2.2 1 1 1 2 2 2 0 Phycobilisome Linker polypeptide UPF0154 PF03672.13 EGG21852.1 - 0.12 12.4 0.0 0.79 9.8 0.0 2.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) DUF3892 PF13031.6 EGG21852.1 - 0.36 11.5 2.8 1.7 9.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3892) TFIIA PF03153.13 EGG21853.1 - 2.9e-10 40.7 51.6 1.2e-08 35.4 38.0 2.4 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF4746 PF15928.5 EGG21853.1 - 0.00012 21.6 10.2 0.0066 15.9 6.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4746) DUF2052 PF09747.9 EGG21853.1 - 0.0044 17.2 13.6 0.0044 17.2 13.6 2.3 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) CLN3 PF02487.17 EGG21853.1 - 0.015 14.3 18.5 0.015 14.4 10.7 2.5 2 0 0 2 2 2 0 CLN3 protein DUF913 PF06025.12 EGG21853.1 - 0.033 13.2 15.5 0.086 11.8 10.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF5308 PF17233.2 EGG21853.1 - 0.033 14.4 18.0 0.14 12.3 12.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Presenilin PF01080.17 EGG21853.1 - 0.036 12.9 29.5 0.021 13.6 21.3 2.3 2 0 0 2 2 2 0 Presenilin SpoIIP PF07454.11 EGG21853.1 - 0.076 12.5 32.5 0.044 13.2 20.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Serinc PF03348.15 EGG21853.1 - 0.16 10.9 16.2 0.078 11.9 9.0 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) TRAP_alpha PF03896.16 EGG21853.1 - 0.21 10.7 12.6 0.52 9.5 7.7 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit RP-C_C PF11800.8 EGG21853.1 - 0.24 11.5 21.9 0.061 13.4 13.6 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region SLC12 PF03522.15 EGG21853.1 - 0.25 10.3 30.4 0.096 11.7 21.1 2.2 2 0 0 2 2 2 0 Solute carrier family 12 CAC1F_C PF16885.5 EGG21853.1 - 0.37 10.4 18.3 0.43 10.2 12.0 2.3 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term Lin-8 PF03353.15 EGG21853.1 - 0.39 10.2 37.7 1.8 8.0 26.8 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CSG2 PF16965.5 EGG21853.1 - 0.45 9.4 16.4 0.37 9.7 9.0 2.5 2 0 0 2 2 2 0 Ceramide synthase regulator Isy1 PF06246.12 EGG21853.1 - 0.55 9.7 25.7 0.3 10.6 18.4 2.2 2 0 0 2 2 2 0 Isy1-like splicing family Zip PF02535.22 EGG21853.1 - 0.85 8.8 10.9 0.48 9.6 4.9 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter ABC2_membrane_2 PF12679.7 EGG21853.1 - 0.88 8.8 4.8 0.28 10.4 1.2 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4484 PF14831.6 EGG21853.1 - 1 9.3 18.2 0.5 10.4 9.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Neur_chan_memb PF02932.16 EGG21853.1 - 1.2 9.2 24.2 5.9 6.9 19.2 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PIP5K PF01504.18 EGG21853.1 - 1.9 7.6 28.7 1.3 8.2 17.5 2.6 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Connexin PF00029.19 EGG21853.1 - 2 8.1 26.9 1.9 8.2 15.4 3.2 3 0 0 3 3 3 0 Connexin DUF3810 PF12725.7 EGG21853.1 - 2.1 7.6 15.5 0.14 11.5 9.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) CCSAP PF15748.5 EGG21853.1 - 2.3 8.3 33.3 0.27 11.4 23.1 2.5 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF4228 PF14009.6 EGG21853.1 - 2.8 8.3 10.6 0.99 9.8 6.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) GNAT_acetyltr_2 PF13718.6 EGG21853.1 - 3.5 7.0 20.4 0.24 10.8 9.9 2.4 2 0 0 2 2 2 0 GNAT acetyltransferase 2 EOS1 PF12326.8 EGG21853.1 - 5 7.0 17.1 6.9 6.6 10.2 2.9 3 0 0 3 3 2 0 N-glycosylation protein eIF-3_zeta PF05091.12 EGG21853.1 - 5.2 5.9 35.2 0.13 11.3 24.8 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Nha1_C PF08619.10 EGG21853.1 - 5.4 6.1 25.4 0.15 11.3 16.7 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Exonuc_VII_L PF02601.15 EGG21853.1 - 6.6 6.2 34.4 9.3 5.7 27.2 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit PTPRCAP PF15713.5 EGG21853.1 - 7.4 6.8 31.6 0.33 11.2 17.2 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PepSY_TM PF03929.16 EGG21853.1 - 8.4 6.0 13.8 33 4.0 12.6 2.0 2 0 0 2 2 2 0 PepSY-associated TM region MMU163 PF17119.5 EGG21853.1 - 8.5 5.4 14.5 3 6.9 9.6 2.3 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Peptidase_S10 PF00450.22 EGG21853.1 - 8.7 5.6 28.4 3.5 6.9 20.4 2.3 2 0 0 2 2 2 0 Serine carboxypeptidase Tim54 PF11711.8 EGG21853.1 - 9.8 4.8 26.7 0.65 8.7 17.9 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 AIF_C PF14721.6 EGG21853.1 - 9.9 6.5 23.8 39 4.6 0.4 2.9 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MIF4G PF02854.19 EGG21854.1 - 5.9e-29 101.2 5.7 5.9e-29 101.2 5.7 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 EGG21854.1 - 1.2e-09 38.2 0.4 5.4e-07 29.6 0.0 2.8 2 1 1 3 3 3 2 MA3 domain YtxC PF08812.11 EGG21854.1 - 0.009 15.7 0.3 0.053 13.1 0.0 2.4 2 0 0 2 2 2 1 YtxC-like family Atx10homo_assoc PF09759.9 EGG21855.1 - 0.0044 17.0 0.7 0.013 15.5 0.7 1.9 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Cast PF10174.9 EGG21856.1 - 7.5e-06 24.5 21.6 1.2e-05 23.8 21.6 1.3 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone FAM184 PF15665.5 EGG21856.1 - 0.0032 17.3 4.4 0.0032 17.3 4.4 2.3 2 0 0 2 2 2 1 Family with sequence similarity 184, A and B TSC22 PF01166.18 EGG21856.1 - 0.01 16.1 21.8 0.67 10.3 1.2 5.2 4 2 0 4 4 4 0 TSC-22/dip/bun family CCDC-167 PF15188.6 EGG21856.1 - 0.018 15.3 0.9 0.018 15.3 0.9 3.4 3 2 0 3 3 3 0 Coiled-coil domain-containing protein 167 Uso1_p115_C PF04871.13 EGG21856.1 - 0.045 14.1 27.9 0.024 15.0 7.4 2.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ATG16 PF08614.11 EGG21856.1 - 0.18 12.0 38.9 3.8 7.7 12.8 3.8 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 EGG21856.1 - 0.29 10.9 37.8 2 8.2 18.6 3.8 4 1 0 4 4 3 0 Coiled-coil region of CCDC155 or KASH TMF_TATA_bd PF12325.8 EGG21856.1 - 0.34 11.2 34.3 1.1 9.5 10.7 4.6 1 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 EGG21856.1 - 0.35 11.4 36.0 0.71 10.4 14.5 3.5 2 1 1 3 3 3 0 Apg6 coiled-coil region NYD-SP28_assoc PF14775.6 EGG21856.1 - 0.39 10.9 0.1 0.39 10.9 0.1 4.4 4 1 0 4 4 4 0 Sperm tail C-terminal domain DUF4407 PF14362.6 EGG21856.1 - 0.52 9.6 20.7 1.5 8.1 10.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Mod_r PF07200.13 EGG21856.1 - 0.64 10.1 39.2 0.066 13.3 16.1 3.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.6 EGG21856.1 - 0.69 9.9 30.0 2.8 7.9 7.7 2.9 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF2937 PF11157.8 EGG21856.1 - 0.74 9.5 8.1 5.7 6.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF848 PF05852.11 EGG21856.1 - 1 9.4 20.0 0.029 14.5 7.3 3.1 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Fez1 PF06818.15 EGG21856.1 - 1.1 9.7 26.9 0.29 11.6 6.6 2.5 1 1 0 2 2 2 0 Fez1 SHE3 PF17078.5 EGG21856.1 - 1.2 8.7 35.3 0.7 9.6 17.5 3.1 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 BAR_3 PF16746.5 EGG21856.1 - 1.5 8.4 25.3 13 5.4 0.0 3.4 2 1 1 3 3 3 0 BAR domain of APPL family CLZ PF16526.5 EGG21856.1 - 2.6 8.4 26.0 4.6 7.7 0.0 4.5 3 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lebercilin PF15619.6 EGG21856.1 - 2.9 7.5 32.6 0.33 10.6 2.9 4.0 3 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease DUF4140 PF13600.6 EGG21856.1 - 3.3 8.2 18.0 1.6 9.2 1.7 4.1 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) ZapB PF06005.12 EGG21856.1 - 3.5 8.1 38.1 2.7 8.5 0.5 4.4 3 1 0 3 3 3 0 Cell division protein ZapB 5_nucleotid PF05761.14 EGG21856.1 - 4.1 6.2 16.4 0.31 9.9 4.8 2.4 2 0 0 2 2 2 0 5' nucleotidase family YabA PF06156.13 EGG21856.1 - 4.2 8.1 30.9 0.57 10.9 5.6 4.0 1 1 1 3 3 3 0 Initiation control protein YabA UPF0242 PF06785.11 EGG21856.1 - 7.5 6.6 40.9 0.054 13.6 19.8 2.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 EGG21856.1 - 9.3 6.7 37.9 0.061 13.7 9.4 4.6 4 1 1 5 5 5 0 Csm1 N-terminal domain EGF_2 PF07974.13 EGG21858.1 - 0.0033 17.7 8.7 0.008 16.5 8.7 1.7 1 0 0 1 1 1 1 EGF-like domain SKG6 PF08693.10 EGG21858.1 - 0.0071 15.7 4.5 0.02 14.3 4.5 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Laminin_EGF PF00053.24 EGG21858.1 - 0.13 12.4 8.7 0.29 11.3 8.7 1.6 1 0 0 1 1 1 0 Laminin EGF domain EGF_Tenascin PF18720.1 EGG21858.1 - 2.1 8.5 5.5 4.7 7.4 5.5 1.7 1 0 0 1 1 1 0 Tenascin EGF domain Amino_oxidase PF01593.24 EGG21859.1 - 6.7e-87 292.6 0.0 1.3e-85 288.4 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 EGG21859.1 - 1.8e-15 57.0 4.6 1e-14 54.6 0.2 2.7 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 EGG21859.1 - 9.2e-10 38.6 0.4 1.8e-09 37.7 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG21859.1 - 3.7e-06 26.4 0.1 5e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGG21859.1 - 0.00012 21.5 0.3 0.00022 20.6 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EGG21859.1 - 0.00012 21.6 0.1 0.00012 21.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGG21859.1 - 0.00018 22.0 2.8 0.004 17.7 0.2 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGG21859.1 - 0.00055 19.6 1.3 0.0011 18.6 1.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EGG21859.1 - 0.00076 18.7 2.2 0.00086 18.5 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGG21859.1 - 0.0016 17.6 0.4 0.0041 16.3 0.4 1.7 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGG21859.1 - 0.0026 16.6 0.9 0.0064 15.2 0.4 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EGG21859.1 - 0.0094 15.2 3.3 0.012 14.9 0.4 2.3 3 0 0 3 3 3 1 FAD binding domain Spore_III_AB PF09548.10 EGG21859.1 - 0.022 14.9 1.0 0.051 13.7 0.1 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Thi4 PF01946.17 EGG21859.1 - 0.062 12.5 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Bombinin PF05298.11 EGG21859.1 - 0.17 11.6 0.3 0.99 9.1 0.1 2.2 2 0 0 2 2 2 0 Bombinin SRI PF08236.11 EGG21859.1 - 2.6 8.3 16.8 0.014 15.5 5.4 2.9 4 0 0 4 4 3 0 SRI (Set2 Rpb1 interacting) domain PH PF00169.29 EGG21861.1 - 3.5e-15 56.4 0.1 1.5e-14 54.4 0.0 2.2 2 0 0 2 2 2 1 PH domain C2 PF00168.30 EGG21861.1 - 7.4e-13 48.7 0.0 7.4e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 C2 domain PH_3 PF14593.6 EGG21861.1 - 4.8e-10 39.5 0.1 1.2e-09 38.2 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGG21861.1 - 1.6e-06 28.3 0.0 3.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EGG21861.1 - 9.3e-05 22.8 0.6 9.3e-05 22.8 0.6 3.5 3 2 0 3 3 3 1 Pleckstrin homology domain SdrD_B PF17210.3 EGG21863.1 - 5.6e-17 62.0 0.6 1.7e-11 44.3 0.0 2.7 2 0 0 2 2 2 2 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG21863.1 - 2.9e-06 27.5 1.7 0.081 13.2 0.3 3.2 2 1 1 3 3 3 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EGG21863.1 - 0.00031 20.7 0.6 1.3 9.0 0.1 3.2 4 0 0 4 4 4 2 CarboxypepD_reg-like domain MetallophosN PF16371.5 EGG21863.1 - 0.03 14.6 0.4 4 7.8 0.0 3.6 3 0 0 3 3 3 0 N terminal of Calcineurin-like phosphoesterase Big_1 PF02369.16 EGG21863.1 - 0.046 13.7 0.4 0.16 12.0 0.1 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) IRF-2BP1_2 PF11261.8 EGG21863.1 - 0.082 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger AMP-binding PF00501.28 EGG21865.1 - 4.2e-78 262.8 0.0 5.7e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG21865.1 - 1.6e-22 80.2 1.1 3e-22 79.4 1.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGG21865.1 - 5e-14 52.0 4.1 1.2e-13 50.8 4.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Macoilin PF09726.9 EGG21865.1 - 0.14 10.7 4.3 0.19 10.2 4.3 1.1 1 0 0 1 1 1 0 Macoilin family IBR PF01485.21 EGG21866.1 - 6.3e-18 64.8 23.4 1.8e-12 47.3 6.3 4.6 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EGG21866.1 - 5.9e-05 23.3 10.9 5.9e-05 23.3 10.9 3.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG21866.1 - 0.00098 18.9 7.6 0.00098 18.9 7.6 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG21866.1 - 0.0018 18.1 10.0 0.0018 18.1 10.0 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF3439 PF11921.8 EGG21866.1 - 0.26 11.2 11.5 2.6 8.0 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) FYDLN_acid PF09538.10 EGG21866.1 - 0.31 11.7 22.4 1.8 9.3 2.5 4.1 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Mid2 PF04478.12 EGG21866.1 - 0.41 10.5 0.0 0.41 10.5 0.0 3.3 4 0 0 4 4 4 0 Mid2 like cell wall stress sensor ANAPC15 PF15243.6 EGG21866.1 - 2.9 8.3 21.3 1.9 8.9 6.5 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Macro PF01661.21 EGG21867.1 - 7.6e-26 90.5 0.3 2e-25 89.1 0.3 1.8 1 0 0 1 1 1 1 Macro domain PARP PF00644.20 EGG21867.1 - 1.7e-15 57.1 8.7 2.2e-15 56.8 1.7 3.4 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain RRM_1 PF00076.22 EGG21867.1 - 1.5e-12 47.2 0.5 5.5e-08 32.5 0.1 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WWE PF02825.20 EGG21867.1 - 6.1e-08 33.1 1.5 1.7e-07 31.7 0.3 2.6 2 0 0 2 2 2 1 WWE domain DUF3084 PF11283.8 EGG21867.1 - 0.0014 18.6 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3084) Glyco_hydro_67N PF03648.14 EGG21867.1 - 0.0051 17.1 0.1 0.034 14.4 0.1 2.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus U-box PF04564.15 EGG21867.1 - 0.0061 16.7 0.0 0.022 14.9 0.0 2.0 1 0 0 1 1 1 1 U-box domain Nup35_RRM_2 PF14605.6 EGG21867.1 - 0.011 15.7 0.0 0.97 9.5 0.0 2.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Tim17 PF02466.19 EGG21868.1 - 9.1e-12 45.3 2.2 1.4e-11 44.8 1.6 1.6 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF2189 PF09955.9 EGG21868.1 - 0.13 12.5 1.8 1.6 9.0 1.2 2.4 1 1 2 3 3 3 0 Predicted integral membrane protein (DUF2189) NUDIX PF00293.28 EGG21869.1 - 7.9e-14 51.8 0.0 1.7e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.12 EGG21869.1 - 0.11 12.9 6.3 1.2 9.5 6.1 2.4 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 EGG21869.1 - 8.7 6.3 7.5 1.6 8.6 0.1 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SSP160 PF06933.11 EGG21870.1 - 0.24 9.6 13.6 0.38 8.9 13.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Period_C PF12114.8 EGG21870.1 - 1.6 8.3 16.3 2.5 7.6 16.3 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Methyltransf_5 PF01795.19 EGG21872.1 - 9.6e-81 271.6 0.0 1.2e-80 271.3 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Ubie_methyltran PF01209.18 EGG21872.1 - 0.015 14.6 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGG21872.1 - 0.1 13.3 0.0 1.6 9.5 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Isochorismatase PF00857.20 EGG21872.1 - 0.19 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Isochorismatase family DUF1084 PF06454.11 EGG21873.1 - 9.9e-15 54.6 14.9 1.3e-14 54.3 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF202 PF02656.15 EGG21873.1 - 0.34 11.4 7.8 5 7.6 1.7 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) APG6 PF04111.12 EGG21874.1 - 9.6e-11 41.9 1.0 1.9e-10 41.0 0.1 2.0 2 0 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 EGG21874.1 - 0.027 15.0 6.2 0.12 12.9 0.0 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region Acyl-CoA_dh_M PF02770.19 EGG21875.1 - 7.2e-16 58.2 0.0 1.2e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGG21875.1 - 1.2e-06 28.9 0.0 2.7e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 EGG21875.1 - 0.00077 19.1 0.1 0.0023 17.5 0.0 1.9 2 1 0 2 2 2 1 Acyl-CoA oxidase Alpha_kinase PF02816.18 EGG21876.1 - 6.8e-60 202.3 0.1 1.4e-59 201.3 0.1 1.6 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.32 EGG21876.1 - 1.7e-31 107.8 18.5 3.6e-05 24.4 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 EGG21876.1 - 5.4e-10 38.5 4.4 0.0082 14.8 0.1 4.6 2 2 2 4 4 4 4 Nucleoporin Nup120/160 WD40_like PF17005.5 EGG21876.1 - 4.2e-08 32.9 0.8 3.9e-06 26.4 0.1 2.3 1 1 1 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 EGG21876.1 - 4.4e-05 23.7 0.1 3.2 8.1 0.0 4.6 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGG21876.1 - 0.00082 19.8 0.1 5.8 7.5 0.0 4.2 4 0 0 4 4 4 1 PQQ-like domain DUF1525 PF07511.11 EGG21876.1 - 0.12 12.5 1.0 0.37 10.9 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) Fez1 PF06818.15 EGG21876.1 - 6.7 7.1 23.5 1.2 9.5 16.8 2.3 2 0 0 2 2 2 0 Fez1 TMEM208_SND2 PF05620.11 EGG21877.1 - 0.015 15.1 0.7 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Shisa PF13908.6 EGG21877.1 - 0.022 15.0 2.7 0.19 11.9 0.9 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 EGG21877.1 - 0.073 14.0 1.0 0.33 11.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CD20 PF04103.15 EGG21877.1 - 0.32 11.1 6.7 0.57 10.3 3.6 2.2 1 1 1 2 2 2 0 CD20-like family ThiF PF00899.21 EGG21879.1 - 1.8e-72 243.6 0.0 3.3e-72 242.8 0.0 1.3 1 1 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EGG21879.1 - 2.5e-18 66.4 0.8 1.6e-17 63.9 0.3 2.4 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EGG21879.1 - 3.3e-06 27.2 5.7 0.00011 22.2 0.2 2.8 3 0 0 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EGG21879.1 - 1.1e-05 25.7 0.0 4.8e-05 23.7 0.0 2.1 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EGG21879.1 - 0.00017 21.8 0.1 0.00081 19.7 0.1 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EGG21879.1 - 0.00022 21.3 0.0 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EGG21879.1 - 0.051 14.1 0.0 0.19 12.3 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.23 EGG21879.1 - 0.067 13.3 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EGG21879.1 - 0.12 11.6 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Bin3 PF06859.12 EGG21881.1 - 5.2e-37 126.8 0.4 5.2e-37 126.8 0.4 2.5 3 0 0 3 3 3 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 EGG21881.1 - 1.5e-09 37.9 0.0 9.5e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG21881.1 - 2.6e-09 37.7 0.1 0.0024 18.5 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGG21881.1 - 9.2e-08 32.8 7.5 0.0036 18.0 0.0 3.6 3 1 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGG21881.1 - 9.8e-08 32.6 0.0 0.041 14.5 0.0 3.1 3 1 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 EGG21881.1 - 1.4e-07 31.5 1.7 0.0004 20.2 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain MTS PF05175.14 EGG21881.1 - 0.00036 20.1 0.0 0.0038 16.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EGG21881.1 - 0.036 13.5 3.9 0.049 13.0 1.4 2.5 2 1 1 3 3 3 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3439 PF11921.8 EGG21881.1 - 0.45 10.5 11.6 1 9.3 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Sin_N PF04801.13 EGG21881.1 - 0.48 9.6 9.5 0.019 14.2 3.4 1.6 2 0 0 2 2 2 0 Sin-like protein conserved region Striatin PF08232.12 EGG21881.1 - 0.67 10.5 17.9 0.064 13.9 6.1 2.3 2 0 0 2 2 2 0 Striatin family Presenilin PF01080.17 EGG21881.1 - 3.8 6.2 13.3 2.2 6.9 4.1 2.0 2 0 0 2 2 2 0 Presenilin SET PF00856.28 EGG21882.1 - 9.2e-10 39.2 9.3 6.3e-08 33.2 9.3 2.3 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGG21882.1 - 5.2e-06 26.5 5.9 5.2e-06 26.5 5.9 2.6 3 0 0 3 3 2 1 MYND finger NPR3 PF03666.13 EGG21882.1 - 0.00017 20.5 3.4 0.00025 20.0 3.4 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 AP3D1 PF06375.11 EGG21882.1 - 0.0004 20.6 6.5 0.00097 19.4 6.5 1.8 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 BUD22 PF09073.10 EGG21882.1 - 0.00046 19.7 10.3 0.00065 19.2 10.3 1.2 1 0 0 1 1 1 1 BUD22 zf-Mss51 PF13824.6 EGG21882.1 - 0.0049 16.9 2.6 0.0049 16.9 2.6 2.2 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF5308 PF17233.2 EGG21882.1 - 0.019 15.2 0.4 0.033 14.4 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DUF4820 PF16091.5 EGG21882.1 - 0.033 13.5 7.7 0.022 14.1 5.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) SR-25 PF10500.9 EGG21882.1 - 0.097 12.3 12.6 0.19 11.3 12.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Coilin_N PF15862.5 EGG21882.1 - 0.15 11.9 8.0 0.36 10.6 8.0 1.7 1 0 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 EGG21882.1 - 0.25 10.1 3.9 0.39 9.4 3.9 1.2 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 EGG21882.1 - 0.62 9.8 12.7 1.5 8.6 12.7 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF913 PF06025.12 EGG21882.1 - 0.93 8.4 3.4 1.4 7.8 3.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MAS20 PF02064.15 EGG21882.1 - 0.98 9.5 8.3 75 3.4 8.9 2.5 2 0 0 2 2 2 0 MAS20 protein import receptor Zip PF02535.22 EGG21882.1 - 1.6 7.9 3.2 2.1 7.5 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 EGG21882.1 - 1.9 7.9 8.4 3.3 7.1 8.4 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 RNA_pol_Rpc4 PF05132.14 EGG21882.1 - 2.5 8.5 8.3 5.3 7.5 8.3 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4746 PF15928.5 EGG21882.1 - 2.7 7.4 11.8 4.7 6.6 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CRA PF06589.11 EGG21882.1 - 3.7 7.7 10.8 10 6.2 10.8 1.7 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) NARP1 PF12569.8 EGG21882.1 - 5.2 5.9 14.1 0.17 10.7 7.9 1.6 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 FancD2 PF14631.6 EGG21882.1 - 9 3.5 9.8 13 3.1 9.8 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Smg4_UPF3 PF03467.15 EGG21883.1 - 5.9e-18 65.5 0.4 7e-18 65.2 0.4 1.2 1 0 0 1 1 1 1 Smg-4/UPF3 family RhoGAP PF00620.27 EGG21883.1 - 0.053 13.4 0.1 0.084 12.7 0.1 1.4 1 0 0 1 1 1 0 RhoGAP domain VEFS-Box PF09733.9 EGG21884.1 - 3.7 7.4 6.5 8.8 6.1 6.5 1.6 1 0 0 1 1 1 0 VEFS-Box of polycomb protein PIP5K PF01504.18 EGG21885.1 - 2.6e-93 312.2 0.5 2.6e-93 312.2 0.5 5.4 3 2 1 4 4 4 1 Phosphatidylinositol-4-phosphate 5-Kinase LAMTOR PF15454.6 EGG21886.1 - 0.0053 17.3 1.0 0.02 15.5 1.0 2.1 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator ParA PF10609.9 EGG21887.1 - 7.7e-97 323.6 0.0 1.1e-96 323.1 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase RNase_T PF00929.24 EGG21887.1 - 2.4e-32 112.7 0.2 5e-32 111.7 0.2 1.6 1 0 0 1 1 1 1 Exonuclease BTB_2 PF02214.22 EGG21887.1 - 3.2e-18 65.9 0.0 2.9e-17 62.8 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain CbiA PF01656.23 EGG21887.1 - 3.2e-11 43.4 0.0 1.5e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGG21887.1 - 7.2e-08 32.6 0.1 3.4e-07 30.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain BTB_3 PF16017.5 EGG21887.1 - 1.5e-07 31.5 0.0 4.8e-06 26.6 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain ArsA_ATPase PF02374.15 EGG21887.1 - 2.9e-06 26.7 0.7 1e-05 24.9 0.4 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 EGG21887.1 - 5.3e-06 25.9 0.0 1.2e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ MeaB PF03308.16 EGG21887.1 - 0.0008 18.5 0.1 0.002 17.1 0.1 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 EGG21887.1 - 0.0029 17.2 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGG21887.1 - 0.0047 16.1 0.0 0.0093 15.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain SRP54 PF00448.22 EGG21887.1 - 0.0052 16.4 0.0 0.025 14.2 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain APS_kinase PF01583.20 EGG21887.1 - 0.01 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase CBP_BcsQ PF06564.12 EGG21887.1 - 0.014 14.9 0.0 0.062 12.8 0.0 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 EGG21887.1 - 0.017 14.5 0.1 0.04 13.4 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 EGG21887.1 - 0.11 12.3 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 EGG21887.1 - 0.16 11.8 0.0 0.5 10.3 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase LRR_4 PF12799.7 EGG21888.1 - 0.018 15.4 11.3 0.42 11.1 0.4 5.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Curto_V2 PF07325.11 EGG21888.1 - 0.15 11.9 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 Curtovirus V2 protein Exo_endo_phos PF03372.23 EGG21889.1 - 2.2e-13 50.2 0.0 3.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EGG21889.1 - 0.063 13.1 0.5 3.5 7.5 0.0 3.1 3 1 1 4 4 4 0 Endonuclease-reverse transcriptase VPS28 PF03997.12 EGG21890.1 - 3.3e-66 222.6 4.2 5.6e-66 221.8 4.2 1.4 1 0 0 1 1 1 1 VPS28 protein PIG-Y PF15159.6 EGG21890.1 - 0.00056 20.8 0.1 0.0017 19.2 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PilM_2 PF11104.8 EGG21890.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Peptidase_M56 PF05569.11 EGG21890.1 - 0.22 10.7 0.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF2353 PF09789.9 EGG21890.1 - 3.1 7.1 7.6 0.045 13.1 0.4 1.6 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Spt4 PF06093.13 EGG21891.1 - 2.7e-26 91.5 0.2 3.5e-26 91.1 0.2 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Exonuc_VII_L PF02601.15 EGG21892.1 - 0.95 9.0 24.4 1.6 8.2 24.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit KAR9 PF08580.10 EGG21892.1 - 7.8 4.9 28.3 10 4.5 28.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Membralin PF09746.9 EGG21892.1 - 8.4 5.3 14.5 13 4.7 14.5 1.3 1 0 0 1 1 1 0 Tumour-associated protein CsbD PF05532.12 EGG21893.1 - 5.2e-05 23.1 0.5 9.9e-05 22.2 0.5 1.4 1 0 0 1 1 1 1 CsbD-like RFC1 PF08519.12 EGG21895.1 - 4e-46 157.0 0.1 4e-46 157.0 0.1 3.2 3 0 0 3 3 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 EGG21895.1 - 2e-12 47.6 0.9 9.5e-12 45.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGG21895.1 - 5e-10 39.6 0.1 1.8e-08 34.5 0.0 3.5 2 1 0 2 2 2 1 Rad17 P-loop domain BRCT PF00533.26 EGG21895.1 - 1.1e-09 38.6 1.6 2.3e-09 37.5 0.1 2.5 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain RuvB_N PF05496.12 EGG21895.1 - 2e-06 27.7 0.0 3.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain PTCB-BRCT PF12738.7 EGG21895.1 - 4.3e-05 23.4 0.1 9.5e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain AAA_22 PF13401.6 EGG21895.1 - 0.00096 19.4 0.0 0.0041 17.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG21895.1 - 0.0034 17.8 1.0 0.0078 16.6 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 EGG21895.1 - 0.004 17.3 0.0 0.023 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGG21895.1 - 0.033 14.2 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGG21895.1 - 0.043 14.2 0.2 0.043 14.2 0.2 3.6 2 2 1 3 3 3 0 RNA helicase TMEM164 PF14808.6 EGG21896.1 - 4e-08 32.9 7.9 1.1e-07 31.5 4.1 2.1 2 0 0 2 2 2 2 TMEM164 family Intg_mem_TP0381 PF09529.10 EGG21896.1 - 1.5e-05 24.7 10.6 1.5e-05 24.7 10.6 2.1 2 0 0 2 2 2 1 Integral membrane protein (intg_mem_TP0381) MMR_HSR1 PF01926.23 EGG21897.1 - 1.5e-07 31.5 0.0 4.3e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EGG21897.1 - 5.4e-06 25.9 1.5 6.2e-06 25.7 0.0 1.9 2 1 0 2 2 2 1 Septin AAA_23 PF13476.6 EGG21897.1 - 3.2e-05 24.5 3.7 3.2e-05 24.5 3.7 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGG21897.1 - 0.00051 20.5 0.0 0.0088 16.4 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGG21897.1 - 0.00052 20.0 1.2 0.0015 18.5 0.1 2.3 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EGG21897.1 - 0.00064 20.0 0.0 0.002 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGG21897.1 - 0.00076 20.0 1.5 0.0037 17.8 0.0 2.5 2 1 0 2 2 2 1 ABC transporter IL4 PF00727.18 EGG21897.1 - 0.00097 19.4 0.6 0.065 13.5 0.2 2.7 2 0 0 2 2 2 1 Interleukin 4 AAA_29 PF13555.6 EGG21897.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Recep_L_domain PF01030.24 EGG21897.1 - 0.013 15.6 0.0 5.3 7.2 0.0 2.8 2 0 0 2 2 2 0 Receptor L domain PduV-EutP PF10662.9 EGG21897.1 - 0.02 14.6 1.6 2.5 7.8 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EGG21897.1 - 0.023 14.2 0.1 0.087 12.4 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRP54 PF00448.22 EGG21897.1 - 0.027 14.1 0.0 3 7.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.23 EGG21897.1 - 0.041 14.0 2.8 0.45 10.6 0.0 2.9 2 1 1 3 3 3 0 Dynamin family DUF1801 PF08818.11 EGG21897.1 - 0.048 14.2 0.2 0.2 12.2 0.0 2.1 2 0 0 2 2 1 0 Domain of unknown function (DU1801) YceD PF02620.17 EGG21897.1 - 0.064 13.4 0.5 0.16 12.1 0.5 1.6 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD Tropomyosin_1 PF12718.7 EGG21897.1 - 0.1 12.8 11.3 0.26 11.4 11.3 1.7 1 1 0 1 1 1 0 Tropomyosin like Amidohydro_1 PF01979.20 EGG21897.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Amidohydrolase family Importin_rep PF18773.1 EGG21897.1 - 0.11 12.2 0.4 0.29 10.9 0.4 1.7 1 0 0 1 1 1 0 Importin 13 repeat DUF2664 PF10867.8 EGG21897.1 - 0.29 11.6 3.8 0.32 11.5 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) TMPIT PF07851.13 EGG21897.1 - 0.32 10.2 5.5 0.65 9.2 5.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein THP2 PF09432.10 EGG21897.1 - 0.64 10.1 8.4 0.54 10.3 3.2 2.7 2 1 0 2 2 2 0 Tho complex subunit THP2 OmpH PF03938.14 EGG21897.1 - 0.72 10.2 9.3 1.3 9.3 9.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SesA PF17107.5 EGG21897.1 - 0.75 10.0 4.4 5.7 7.2 3.4 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Skp1_POZ PF03931.15 EGG21898.1 - 0.047 13.9 0.2 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Syntaxin_2 PF14523.6 EGG21898.1 - 0.11 12.9 3.0 0.25 11.7 3.0 1.6 1 0 0 1 1 1 0 Syntaxin-like protein DUF4179 PF13786.6 EGG21898.1 - 0.15 12.6 0.2 0.73 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) ABC_tran PF00005.27 EGG21899.1 - 5.4e-08 33.4 1.5 0.00061 20.3 0.0 4.2 3 1 0 3 3 3 2 ABC transporter MMR_HSR1 PF01926.23 EGG21899.1 - 1.3e-07 31.7 0.0 0.00059 19.9 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG21899.1 - 4.4e-06 26.7 0.1 0.029 14.3 0.0 3.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGG21899.1 - 1.4e-05 24.7 0.6 0.011 15.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGG21899.1 - 0.00014 22.2 0.0 0.89 9.8 0.0 4.0 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 EGG21899.1 - 0.00039 20.0 0.0 0.2 11.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 EGG21899.1 - 0.0013 18.9 0.0 0.4 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGG21899.1 - 0.0062 16.9 0.2 2.4 8.5 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EGG21899.1 - 0.016 15.5 0.7 19 5.7 0.0 4.0 3 0 0 3 3 3 0 RNA helicase SMC_N PF02463.19 EGG21899.1 - 0.029 13.8 0.9 1 8.8 0.1 2.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EGG21899.1 - 0.039 13.0 0.1 2.8 6.9 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 EGG21899.1 - 0.065 12.6 0.0 5 6.5 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Transp_Tc5_C PF04236.15 EGG21899.1 - 1.5 9.3 9.8 5.3 7.5 9.8 2.0 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain MORN PF02493.20 EGG21900.1 - 0.00024 20.8 0.2 0.00024 20.8 0.2 3.4 4 0 0 4 4 4 1 MORN repeat MMR_HSR1 PF01926.23 EGG21901.1 - 9e-06 25.8 0.0 2.8e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG21901.1 - 0.00064 19.7 0.0 0.0019 18.1 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EGG21901.1 - 0.00069 20.1 0.1 0.0026 18.3 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Septin PF00735.18 EGG21901.1 - 0.0013 18.1 0.2 0.0045 16.3 0.0 2.0 2 0 0 2 2 2 1 Septin AAA_23 PF13476.6 EGG21901.1 - 0.0016 19.0 16.5 0.73 10.3 16.1 3.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGG21901.1 - 0.0032 17.2 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 EGG21901.1 - 0.026 14.6 3.3 0.19 11.8 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain GTP_EFTU PF00009.27 EGG21901.1 - 0.047 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF4523 PF15023.6 EGG21901.1 - 0.095 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) AAA_22 PF13401.6 EGG21901.1 - 0.11 12.7 0.0 1.5 9.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EGG21901.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 EGG21901.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EGG21901.1 - 4.6 7.3 7.9 3 7.9 0.0 3.3 3 1 0 4 4 4 0 Dynamin family LMBR1 PF04791.16 EGG21903.1 - 2.3e-43 148.9 37.3 1.3e-31 110.1 9.7 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein FtsH_ext PF06480.15 EGG21903.1 - 0.49 10.8 0.0 0.49 10.8 0.0 4.6 5 0 0 5 5 5 0 FtsH Extracellular Phg_2220_C PF09524.10 EGG21904.1 - 0.0023 17.9 0.9 0.016 15.3 0.4 2.6 1 1 1 2 2 2 1 Conserved phage C-terminus (Phg_2220_C) TTRAP PF14203.6 EGG21904.1 - 0.011 15.7 0.0 0.056 13.4 0.0 2.2 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein RsgA_GTPase PF03193.16 EGG21904.1 - 0.012 15.5 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 EGG21904.1 - 0.016 15.7 1.6 0.077 13.5 0.1 2.4 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EGG21904.1 - 0.028 14.8 0.0 0.17 12.2 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain Peptidase_S24 PF00717.23 EGG21904.1 - 0.16 12.0 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Peptidase S24-like MMR_HSR1 PF01926.23 EGG21904.1 - 0.22 11.6 0.7 0.71 10.0 0.1 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 EGG21904.1 - 0.38 11.2 12.3 0.015 15.8 2.0 3.0 1 1 1 2 2 2 0 AAA domain DUF4745 PF15923.5 EGG21904.1 - 0.6 10.1 2.9 3.2 7.7 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4745) DUF87 PF01935.17 EGG21904.1 - 0.78 9.8 5.6 21 5.1 0.1 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain PfkB PF00294.24 EGG21905.1 - 2.6e-60 204.3 0.5 3.6e-60 203.8 0.5 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phosphodiest PF01663.22 EGG21906.1 - 7.2e-76 256.1 0.3 9.2e-76 255.7 0.3 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGG21906.1 - 4.8e-05 22.9 0.1 0.015 14.7 0.1 2.7 1 1 0 2 2 2 2 Sulfatase DUF229 PF02995.17 EGG21906.1 - 0.005 15.5 0.0 0.0071 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) PglZ PF08665.12 EGG21906.1 - 0.041 14.0 0.1 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 PglZ domain DUF1501 PF07394.12 EGG21906.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) UCH PF00443.29 EGG21908.1 - 8.3e-43 146.7 12.1 8.3e-43 146.7 12.1 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG21908.1 - 5.4e-12 45.9 29.7 5.4e-12 45.9 29.7 3.7 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EGG21908.1 - 0.011 15.2 10.3 0.66 9.4 0.1 3.8 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-C2H2_2 PF12756.7 EGG21908.1 - 0.21 12.0 5.1 0.81 10.1 0.6 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) MM_CoA_mutase PF01642.22 EGG21909.1 - 1.7e-235 782.5 0.0 2e-235 782.2 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 EGG21909.1 - 4.1e-15 55.9 0.3 8.6e-15 54.9 0.3 1.6 1 0 0 1 1 1 1 B12 binding domain PhnI PF05861.12 EGG21909.1 - 0.09 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Pkinase PF00069.25 EGG21910.1 - 1.3e-45 155.8 0.3 3e-33 115.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21910.1 - 7.7e-30 104.0 0.0 1.7e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Acetyltransf_1 PF00583.25 EGG21910.1 - 4e-05 23.8 0.0 7.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG21910.1 - 0.0067 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG21910.1 - 0.016 15.6 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Met_10 PF02475.16 EGG21911.1 - 1.3e-60 204.6 0.0 2.1e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 EGG21911.1 - 0.0017 17.8 0.0 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGG21911.1 - 0.01 15.4 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain TRM PF02005.16 EGG21911.1 - 0.033 13.4 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Menin PF05053.13 EGG21911.1 - 3.6 5.8 8.9 5.6 5.2 8.9 1.2 1 0 0 1 1 1 0 Menin Coilin_N PF15862.5 EGG21912.1 - 8.7e-05 22.3 0.0 0.0026 17.6 0.0 3.0 2 1 0 2 2 2 1 Coilin N-terminus LRR_6 PF13516.6 EGG21912.1 - 0.00014 21.6 15.7 2.6 8.3 0.6 7.4 7 0 0 7 7 7 3 Leucine Rich repeat DUF4411 PF14367.6 EGG21913.1 - 0.0022 17.9 0.1 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4411) PAP1 PF08601.10 EGG21914.1 - 0.24 11.1 4.3 0.54 9.9 4.3 1.5 1 0 0 1 1 1 0 Transcription factor PAP1 DUF3447 PF11929.8 EGG21915.1 - 8.3 6.4 21.1 0.29 11.1 0.5 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF3447) BTB PF00651.31 EGG21917.1 - 7.6e-23 80.9 3.1 1.6e-21 76.6 2.2 2.9 1 1 1 2 2 2 1 BTB/POZ domain DUSP PF06337.12 EGG21917.1 - 2.6e-05 24.8 0.2 2.6e-05 24.8 0.2 3.6 4 1 0 4 4 4 1 DUSP domain BACK PF07707.15 EGG21917.1 - 0.01 15.9 4.1 0.12 12.5 0.0 3.2 3 0 0 3 3 3 0 BTB And C-terminal Kelch SSP160 PF06933.11 EGG21917.1 - 1.3 7.2 7.2 1.9 6.6 7.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 EamA PF00892.20 EGG21918.1 - 9.3e-36 123.0 39.9 5.7e-19 68.6 17.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EGG21918.1 - 0.00017 20.9 1.6 0.00017 20.9 1.6 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.16 EGG21918.1 - 0.00035 20.0 20.5 0.00052 19.5 20.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF2371 PF10177.9 EGG21918.1 - 0.62 10.2 0.0 0.62 10.2 0.0 3.3 4 1 0 4 4 4 0 Uncharacterised conserved protein (DUF2371) UPF0239 PF06783.11 EGG21918.1 - 0.67 10.2 0.0 0.67 10.2 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) DUF2101 PF09874.9 EGG21918.1 - 4.6 6.9 8.1 3.3 7.4 5.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) Glycos_transf_2 PF00535.26 EGG21919.1 - 7.8e-20 71.4 0.0 1.8e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGG21919.1 - 2.4e-10 40.7 0.0 1.4e-07 31.7 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase like family 2 EcoEI_R_C PF08463.10 EGG21919.1 - 0.058 13.5 0.0 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 EcoEI R protein C-terminal SR-25 PF10500.9 EGG21919.1 - 2 8.0 11.0 3.6 7.1 11.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 EGG21919.1 - 2.1 8.7 15.8 1.9 8.9 13.4 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain COMM_domain PF07258.14 EGG21920.1 - 3.2e-19 68.8 3.6 3.2e-19 68.8 3.6 2.1 2 1 0 2 2 2 1 COMM domain TFIIE_alpha PF02002.17 EGG21920.1 - 0.2 11.5 3.0 0.83 9.5 0.4 2.9 2 1 0 2 2 2 0 TFIIE alpha subunit SapB_2 PF03489.17 EGG21921.1 - 2.1e-07 30.9 0.9 4.3e-07 29.9 0.9 1.5 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.15 EGG21921.1 - 0.0017 18.3 0.1 0.0017 18.3 0.1 2.8 3 0 0 3 3 3 1 Saposin-like type B, region 1 Cons_hypoth698 PF03601.14 EGG21921.1 - 0.082 11.8 1.4 0.1 11.5 1.4 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 698 YqfQ PF14181.6 EGG21921.1 - 1.4 9.1 5.5 5.4 7.2 0.0 2.1 2 0 0 2 2 2 0 YqfQ-like protein Med26 PF08711.11 EGG21922.1 - 2.5e-12 46.6 0.4 8e-12 45.0 0.4 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain gpW PF02831.15 EGG21922.1 - 0.38 10.7 2.3 4.1 7.4 0.0 2.5 2 0 0 2 2 2 0 gpW DUF2439 PF10382.9 EGG21924.1 - 1.4e-15 57.4 0.4 1.4e-15 57.4 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) PH PF00169.29 EGG21924.1 - 0.071 13.6 0.1 0.24 11.9 0.1 2.0 1 0 0 1 1 1 0 PH domain Asp-B-Hydro_N PF05279.11 EGG21924.1 - 1.4 8.9 10.5 2.3 8.2 10.5 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-GRF PF06839.12 EGG21925.1 - 1.3e-08 34.7 2.1 3.3e-08 33.5 2.1 1.7 1 0 0 1 1 1 1 GRF zinc finger AAA_12 PF13087.6 EGG21926.1 - 8.2e-46 156.1 0.1 5.9e-45 153.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGG21926.1 - 1.3e-18 67.7 3.5 2e-16 60.6 0.1 3.0 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EGG21926.1 - 3.7e-08 33.4 0.0 0.0083 15.9 0.0 2.5 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EGG21926.1 - 0.0005 19.8 0.0 0.0025 17.6 0.0 2.2 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 EGG21926.1 - 0.00088 18.7 0.0 0.8 9.0 0.1 2.2 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EGG21926.1 - 0.0027 18.1 0.0 0.085 13.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain DUF4241 PF14025.6 EGG21926.1 - 0.13 12.5 0.5 0.24 11.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) N2227 PF07942.12 EGG21927.1 - 1.9e-81 273.2 0.0 3.3e-81 272.4 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EGG21927.1 - 0.0048 16.8 0.0 0.012 15.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG21927.1 - 0.025 15.3 0.2 0.17 12.7 0.0 2.6 3 1 0 3 3 3 0 Methyltransferase domain DUF5579 PF17742.1 EGG21927.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5579) BUD22 PF09073.10 EGG21927.1 - 0.98 8.7 9.5 1.3 8.3 9.5 1.1 1 0 0 1 1 1 0 BUD22 GEMIN8 PF15348.6 EGG21927.1 - 3.5 7.9 13.4 18 5.5 9.6 2.2 1 1 1 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Zip PF02535.22 EGG21927.1 - 4.7 6.3 4.9 5.5 6.1 4.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Dicty_CTDC PF00526.18 EGG21928.1 - 0.00015 21.5 3.9 0.00015 21.5 3.9 10.5 10 0 0 10 10 10 3 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGG21928.1 - 0.039 13.8 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 PA14 domain Malate_synthase PF01274.22 EGG21929.1 - 4.5e-203 675.3 0.0 5.7e-203 674.9 0.0 1.1 1 0 0 1 1 1 1 Malate synthase Nas2_N PF18265.1 EGG21929.1 - 1.5e-14 53.6 0.1 3.6e-07 30.0 0.1 2.8 2 0 0 2 2 2 2 Nas2 N_terminal domain DUF2868 PF11067.8 EGG21929.1 - 0.018 14.6 0.5 0.028 14.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) YdaS_antitoxin PF15943.5 EGG21929.1 - 0.037 13.9 0.1 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HpcH_HpaI PF03328.14 EGG21929.1 - 0.069 12.3 0.0 0.16 11.1 0.0 1.7 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Peptidase_S49_N PF08496.10 EGG21930.1 - 0.91 9.6 16.3 1 9.4 7.3 2.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RecG_N PF17190.4 EGG21930.1 - 8.6 7.2 7.8 0.96 10.2 0.8 2.4 2 1 0 2 2 2 0 RecG N-terminal helical domain Acetyltransf_1 PF00583.25 EGG21931.1 - 5.4e-14 52.4 0.0 7.9e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG21931.1 - 2.4e-10 40.4 0.1 2.9e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG21931.1 - 1.7e-07 31.6 0.0 2.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG21931.1 - 1.3e-05 25.1 0.1 1.9e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 EGG21931.1 - 0.028 14.4 0.1 0.051 13.6 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.7 EGG21931.1 - 0.036 14.7 0.0 0.054 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MAGE PF01454.19 EGG21931.1 - 0.041 13.6 0.7 0.052 13.2 0.7 1.2 1 0 0 1 1 1 0 MAGE family Acetyltransf_9 PF13527.7 EGG21931.1 - 0.062 13.4 0.1 0.12 12.4 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SAC3_GANP PF03399.16 EGG21932.1 - 5.5e-10 39.1 9.7 5.5e-10 39.1 9.7 2.9 3 1 0 3 3 3 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EGG21932.1 - 2.5e-06 27.5 0.5 9.9e-06 25.6 0.5 1.9 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family AAA_16 PF13191.6 EGG21933.1 - 0.0028 18.0 0.0 0.005 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EGG21933.1 - 0.031 14.3 0.3 0.31 11.1 0.4 2.3 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGG21933.1 - 0.034 13.3 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 EGG21933.1 - 0.035 14.1 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EGG21933.1 - 0.098 13.1 0.0 0.33 11.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGG21933.1 - 0.12 12.6 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 EGG21934.1 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EGG21934.1 - 0.1 12.5 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 F-box domain RhoGAP-FF1 PF16512.5 EGG21934.1 - 0.13 13.0 2.2 0.89 10.3 0.2 2.5 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain HECT PF00632.25 EGG21935.1 - 3.8e-99 332.0 0.1 1.7e-98 329.9 0.3 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 EGG21935.1 - 1.2e-34 119.9 1.7 2.1e-33 115.8 0.2 7.9 8 2 1 9 9 9 2 Domain of Unknown Function (DUF913) UBM PF14377.6 EGG21935.1 - 2e-18 65.2 22.8 6.9e-09 34.9 3.6 4.7 3 1 1 4 4 4 3 Ubiquitin binding region UBA PF00627.31 EGG21935.1 - 0.0099 15.8 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DUF908 PF06012.12 EGG21936.1 - 8.4e-16 58.3 2.7 8.4e-16 58.3 2.7 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) Bul1_N PF04425.12 EGG21936.1 - 0.0063 15.3 4.9 0.011 14.6 4.9 1.3 1 0 0 1 1 1 1 Bul1 N terminus DUF1708 PF08101.11 EGG21936.1 - 0.012 14.8 4.1 0.049 12.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1708) DUF4667 PF15700.5 EGG21936.1 - 0.15 12.1 12.8 0.11 12.6 8.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) Pex14_N PF04695.13 EGG21936.1 - 0.64 10.7 8.7 0.069 13.8 3.9 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EST1 PF10374.9 EGG21936.1 - 0.91 10.2 4.7 0.94 10.1 2.7 1.9 2 0 0 2 2 2 0 Telomerase activating protein Est1 SSP160 PF06933.11 EGG21936.1 - 1.2 7.3 27.6 0.25 9.5 0.8 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 ATG16 PF08614.11 EGG21936.1 - 7.5 6.7 6.0 2.7 8.2 2.6 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) AMP-binding PF00501.28 EGG21937.1 - 3.2e-20 72.1 0.0 8.6e-20 70.7 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme zf-HIT PF04438.16 EGG21938.1 - 3.9e-09 36.2 13.8 6.6e-09 35.5 13.8 1.4 1 0 0 1 1 1 1 HIT zinc finger NABP PF07990.12 EGG21938.1 - 0.084 12.4 0.2 0.1 12.1 0.2 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP OPA3 PF07047.12 EGG21939.1 - 1.5e-22 79.7 2.6 1.5e-22 79.7 2.6 2.3 2 1 0 2 2 1 1 Optic atrophy 3 protein (OPA3) TssO PF17561.2 EGG21939.1 - 0.0094 16.1 1.4 0.025 14.7 0.5 2.3 2 0 0 2 2 2 1 Type VI secretion system, TssO Cytomega_UL84 PF06284.11 EGG21939.1 - 0.039 12.4 0.4 0.074 11.5 0.4 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CENP-B_dimeris PF09026.10 EGG21939.1 - 0.065 13.6 2.3 0.27 11.6 0.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ribosomal_60s PF00428.19 EGG21939.1 - 0.098 13.3 0.1 0.098 13.3 0.1 1.7 2 0 0 2 2 1 0 60s Acidic ribosomal protein DUF3949 PF13133.6 EGG21939.1 - 0.11 13.0 1.6 2.6 8.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) Ly49 PF08391.10 EGG21939.1 - 0.14 12.5 3.4 0.46 10.9 3.4 1.8 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Afi1 PF07792.12 EGG21939.1 - 0.69 10.4 10.2 1.1 9.7 1.5 2.5 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CSRNP_N PF16019.5 EGG21939.1 - 0.74 9.7 7.4 2 8.3 0.2 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus FAM176 PF14851.6 EGG21939.1 - 2 8.1 14.3 0.18 11.5 0.9 2.9 2 1 0 2 2 2 0 FAM176 family NST1 PF13945.6 EGG21939.1 - 2.2 8.4 17.0 0.37 10.9 2.3 2.5 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF4175 PF13779.6 EGG21939.1 - 2.6 5.8 7.9 0.38 8.6 3.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF2956 PF11169.8 EGG21939.1 - 3.4 7.9 8.4 0.23 11.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Peptidase_S9 PF00326.21 EGG21941.1 - 1.2e-35 122.9 0.0 2.5e-35 121.9 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EGG21941.1 - 2.3e-06 27.3 0.0 5.6e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EGG21941.1 - 6e-05 22.4 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EGG21941.1 - 0.0091 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 EGG21941.1 - 0.021 14.4 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EGG21941.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold ODV-E18 PF10717.9 EGG21941.1 - 0.33 10.8 2.6 0.89 9.5 2.6 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 HSP20 PF00011.21 EGG21942.1 - 5.5e-23 81.1 0.2 7.1e-23 80.7 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG21942.1 - 7.7e-06 25.4 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA SPT_ssu-like PF11779.8 EGG21943.1 - 0.0034 17.0 1.0 0.0049 16.5 1.0 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like RCC1 PF00415.18 EGG21944.1 - 1e-42 144.5 27.1 1.2e-11 45.0 0.2 7.1 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG21944.1 - 1.5e-17 62.9 36.3 1.5e-07 31.0 0.9 7.8 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat ERCC4 PF02732.15 EGG21945.1 - 1.6e-15 57.7 0.1 6.1e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 ERCC4 domain tRNA-synt_1d PF00750.19 EGG21946.1 - 4e-56 190.5 3.2 1.5e-29 103.1 0.2 4.3 2 1 0 3 3 3 3 tRNA synthetases class I (R) DALR_1 PF05746.15 EGG21946.1 - 1e-23 83.8 0.1 4.2e-23 81.8 0.0 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EGG21946.1 - 0.00078 20.0 0.0 0.0081 16.7 0.0 2.5 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Poxvirus_B22R PF04395.12 EGG21946.1 - 0.01 15.4 0.4 0.053 13.1 0.1 2.2 2 0 0 2 2 2 0 Poxvirus B22R protein tRNA-synt_1 PF00133.22 EGG21946.1 - 0.011 14.0 0.0 0.051 11.8 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) DUF3439 PF11921.8 EGG21946.1 - 0.063 13.2 5.0 0.14 12.2 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4041 PF13250.6 EGG21946.1 - 0.087 12.7 0.5 0.64 9.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) THP2 PF09432.10 EGG21947.1 - 0.05 13.6 1.0 0.11 12.6 1.0 1.5 1 1 0 1 1 1 0 Tho complex subunit THP2 F-box-like PF12937.7 EGG21947.1 - 0.083 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EGG21949.1 - 0.035 14.0 1.5 0.12 12.3 0.5 2.5 2 0 0 2 2 2 0 F-box domain Methyltransf_23 PF13489.6 EGG21950.1 - 4.5e-19 68.9 0.0 6.6e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG21950.1 - 8.1e-18 64.9 0.0 2.9e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG21950.1 - 2e-14 53.6 0.0 3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG21950.1 - 1.9e-13 51.0 0.0 3.8e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG21950.1 - 4.7e-13 49.7 2.0 8.6e-13 48.9 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EGG21950.1 - 6.2e-09 35.6 0.0 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EGG21950.1 - 4.8e-07 29.5 0.2 4.8e-07 29.5 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 EGG21950.1 - 5.4e-06 26.2 0.0 9.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 EGG21950.1 - 9.6e-06 24.7 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EGG21950.1 - 9.9e-06 25.2 0.1 2.4e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EGG21950.1 - 1.3e-05 24.7 0.1 2.7e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 EGG21950.1 - 2.1e-05 24.5 1.9 3.1e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG21950.1 - 0.00066 19.1 0.0 0.00094 18.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GidB PF02527.15 EGG21950.1 - 0.0037 16.6 0.8 0.022 14.1 0.8 2.0 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G PCMT PF01135.19 EGG21950.1 - 0.041 13.6 0.1 0.1 12.3 0.1 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EGG21950.1 - 0.049 13.1 0.8 11 5.5 0.0 2.9 3 0 0 3 3 3 0 Putative methyltransferase TPMT PF05724.11 EGG21950.1 - 0.11 12.2 0.0 0.27 10.8 0.0 1.7 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) N2227 PF07942.12 EGG21950.1 - 0.12 11.6 0.1 0.12 11.6 0.1 2.4 2 1 1 3 3 3 0 N2227-like protein SWIM PF04434.17 EGG21951.1 - 0.062 13.0 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 SWIM zinc finger YL1 PF05764.13 EGG21951.1 - 0.43 10.6 3.6 0.64 10.1 3.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF3835 PF12927.7 EGG21951.1 - 3.8 8.4 6.2 2.4 9.1 1.2 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3835) Lipase_3 PF01764.25 EGG21952.1 - 2.3e-31 108.5 0.0 4.2e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EGG21952.1 - 8.9e-06 25.4 0.0 2.9e-05 23.8 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EGG21952.1 - 0.0026 18.4 0.0 0.0041 17.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EGG21952.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family ARID PF01388.21 EGG21953.1 - 6.6e-18 65.2 0.1 4.3e-17 62.6 0.0 2.5 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain SAP30_Sin3_bdg PF13867.6 EGG21953.1 - 3.1e-16 59.4 0.3 3.1e-16 59.4 0.3 3.0 3 1 0 3 3 3 1 Sin3 binding region of histone deacetylase complex subunit SAP30 TAS2R PF05296.13 EGG21955.1 - 0.0026 16.9 0.7 0.0028 16.8 0.7 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) SapB_2 PF03489.17 EGG21956.1 - 0.023 14.8 1.1 0.19 11.8 1.1 2.5 1 1 0 1 1 1 0 Saposin-like type B, region 2 MASE4 PF17158.4 EGG21956.1 - 0.025 13.8 0.4 0.037 13.3 0.4 1.2 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain OS-D PF03392.13 EGG21956.1 - 0.063 13.4 7.6 0.15 12.2 1.7 2.2 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D OCRE PF17780.1 EGG21957.1 - 1e-09 38.2 9.4 1e-09 38.2 9.4 2.5 2 0 0 2 2 2 1 OCRE domain RRM_1 PF00076.22 EGG21957.1 - 0.0014 18.4 0.0 0.004 16.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 EGG21957.1 - 0.014 14.7 11.1 0.035 13.4 11.1 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others G-patch PF01585.23 EGG21957.1 - 0.033 14.1 0.3 0.23 11.4 0.1 2.3 2 0 0 2 2 2 0 G-patch domain zf-C2H2_6 PF13912.6 EGG21957.1 - 0.04 13.9 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EGG21957.1 - 0.072 13.0 0.1 0.072 13.0 0.1 2.6 2 1 1 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 EGG21957.1 - 0.12 13.3 0.1 0.12 13.3 0.1 3.2 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGG21957.1 - 7.9 7.2 9.9 0.18 12.3 0.4 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type SPT2 PF08243.11 EGG21958.1 - 4e-09 37.0 31.3 4e-09 37.0 31.3 4.6 2 1 1 3 3 3 1 SPT2 chromatin protein Arm_2 PF04826.13 EGG21958.1 - 0.0026 17.3 4.2 0.034 13.6 3.7 2.2 1 1 1 2 2 2 1 Armadillo-like DUF3915 PF13054.6 EGG21958.1 - 0.0063 16.5 4.8 0.0063 16.5 4.8 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3915) V-ATPase_H_C PF11698.8 EGG21958.1 - 0.073 13.2 0.5 25 5.0 0.0 3.4 3 1 0 3 3 3 0 V-ATPase subunit H Arm PF00514.23 EGG21958.1 - 0.092 12.8 1.1 1.1e+02 3.1 0.0 5.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Patatin PF01734.22 EGG21959.1 - 2.8e-16 60.3 0.0 8.9e-16 58.7 0.0 2.0 1 0 0 1 1 1 1 Patatin-like phospholipase PH PF00169.29 EGG21959.1 - 2.4e-07 31.2 5.2 1e-06 29.2 5.2 2.2 1 1 0 1 1 1 1 PH domain FAD_binding_3 PF01494.19 EGG21960.1 - 9.3e-19 67.9 0.0 1.6e-18 67.1 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DUF2312 PF10073.9 EGG21960.1 - 0.02 14.5 0.0 0.24 11.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) DAO PF01266.24 EGG21960.1 - 0.023 14.3 0.0 0.29 10.7 0.0 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase DUF3899 PF13038.6 EGG21960.1 - 0.033 14.7 0.5 0.2 12.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Pyr_redox_2 PF07992.14 EGG21960.1 - 0.034 13.4 0.1 0.91 8.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EcsB PF05975.12 EGG21960.1 - 0.034 13.0 1.4 0.05 12.5 1.4 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB SRP9-21 PF05486.12 EGG21960.1 - 0.071 13.5 0.2 0.16 12.3 0.2 1.5 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) NAD_binding_8 PF13450.6 EGG21960.1 - 0.084 13.1 0.0 0.42 10.9 0.0 2.1 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGG21961.1 - 6.6e-33 114.4 0.1 1.2e-32 113.6 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain NP1-WLL PF11733.8 EGG21961.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Non-capsid protein NP1 Lactamase_B PF00753.27 EGG21962.1 - 7.1e-10 39.2 0.0 1.8e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGG21962.1 - 2.4e-09 37.0 0.0 4.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain cNMP_binding PF00027.29 EGG21962.1 - 4.7e-09 36.2 0.0 1.2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Lactamase_B_3 PF13483.6 EGG21962.1 - 0.051 13.5 0.0 0.29 11.0 0.0 2.2 2 1 0 2 2 2 0 Beta-lactamase superfamily domain EP400_N PF15790.5 EGG21963.1 - 0.11 11.3 4.0 0.26 10.1 4.0 1.5 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal Ras PF00071.22 EGG21964.1 - 3.2e-59 199.1 0.1 4e-59 198.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG21964.1 - 4.4e-20 72.1 0.0 6.7e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG21964.1 - 7.7e-08 32.0 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGG21964.1 - 0.0075 16.2 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGG21964.1 - 0.014 15.0 0.1 0.038 13.5 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGG21964.1 - 0.017 14.7 0.0 0.091 12.3 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B ArsR PF09824.9 EGG21964.1 - 0.12 12.0 0.2 0.34 10.5 0.1 1.7 2 0 0 2 2 2 0 ArsR transcriptional regulator Methyltransf_2 PF00891.18 EGG21965.1 - 2.7e-38 131.4 0.0 4.7e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGG21965.1 - 5.9e-06 26.2 0.0 1.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.12 EGG21965.1 - 0.00014 22.5 0.1 0.0074 17.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG21965.1 - 0.0019 18.0 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG21965.1 - 0.0048 16.7 0.3 0.013 15.2 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG21965.1 - 0.011 16.5 0.0 0.035 14.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain TrmB PF01978.19 EGG21965.1 - 0.011 15.6 0.0 0.082 12.8 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Methyltransf_11 PF08241.12 EGG21965.1 - 0.017 15.7 0.0 0.34 11.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Rrf2 PF02082.20 EGG21965.1 - 0.092 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator Dimerisation PF08100.11 EGG21965.1 - 0.17 11.9 0.0 0.6 10.2 0.0 2.0 2 0 0 2 2 2 0 Dimerisation domain TIG PF01833.24 EGG21966.1 - 0.0012 18.8 2.4 0.0012 18.8 2.4 4.2 3 1 0 3 3 3 1 IPT/TIG domain LRR_8 PF13855.6 EGG21966.1 - 0.24 11.2 3.8 0.18 11.6 0.5 2.4 2 0 0 2 2 2 0 Leucine rich repeat EGF_2 PF07974.13 EGG21966.1 - 0.5 10.8 14.1 1.5 9.3 14.1 1.8 1 0 0 1 1 1 0 EGF-like domain zinc_ribbon_2 PF13240.6 EGG21968.1 - 0.00013 21.5 2.2 0.00035 20.2 2.2 1.8 1 1 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EGG21968.1 - 0.00017 21.6 0.9 0.00038 20.4 0.9 1.6 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 EGG21968.1 - 0.0014 18.0 2.9 0.0043 16.4 2.9 1.9 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 EGG21968.1 - 0.06 14.1 0.6 0.06 14.1 0.6 2.1 2 0 0 2 2 2 0 zinc-ribbon family Nudix_N_2 PF14803.6 EGG21968.1 - 0.098 12.6 3.2 4 7.4 0.2 2.5 2 0 0 2 2 2 0 Nudix N-terminal Patched PF02460.18 EGG21969.1 - 7.2e-89 298.9 15.4 1.7e-88 297.7 15.4 1.6 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EGG21969.1 - 1.1e-48 164.9 23.2 7.2e-47 159.0 7.1 3.2 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 EGG21969.1 - 1.5e-26 93.4 8.3 2.7e-26 92.6 8.3 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus ACR_tran PF00873.19 EGG21969.1 - 0.021 12.5 17.0 0.039 11.6 17.0 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family OppC_N PF12911.7 EGG21969.1 - 0.074 13.0 0.0 0.074 13.0 0.0 3.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF3624 PF12292.8 EGG21969.1 - 2.1 8.8 10.5 1.8 9.0 2.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3624) RRM_1 PF00076.22 EGG21970.1 - 1.3e-41 140.3 0.5 3.4e-16 58.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med15 PF09606.10 EGG21970.1 - 0.00013 20.9 26.0 0.00017 20.5 26.0 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal RRM_7 PF16367.5 EGG21970.1 - 0.032 14.3 1.8 40 4.4 0.0 4.2 4 1 1 5 5 5 0 RNA recognition motif RRM_occluded PF16842.5 EGG21970.1 - 0.04 13.8 0.1 7.6 6.5 0.1 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif Draxin PF15550.6 EGG21970.1 - 0.58 10.0 7.2 1.1 9.0 7.2 1.4 1 0 0 1 1 1 0 Draxin zf-RING_5 PF14634.6 EGG21972.1 - 0.00021 21.2 9.7 0.00021 21.2 9.7 8.0 7 2 1 8 8 8 2 zinc-RING finger domain zf-RING_2 PF13639.6 EGG21972.1 - 0.0037 17.5 9.4 0.0037 17.5 9.4 7.7 7 2 0 7 7 7 3 Ring finger domain zf-RING_UBOX PF13445.6 EGG21972.1 - 0.0048 16.9 4.5 0.0048 16.9 4.5 6.2 5 2 1 6 6 6 2 RING-type zinc-finger Cytochrome_B PF00033.19 EGG21974.1 - 0.0037 17.1 0.0 0.0043 16.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB PIG-Y PF15159.6 EGG21974.1 - 0.01 16.7 1.9 0.025 15.5 0.4 1.9 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Cation_ATPase_C PF00689.21 EGG21974.1 - 0.019 14.7 1.6 0.02 14.6 1.6 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus WH2 PF02205.20 EGG21976.1 - 5.4e-11 42.0 1.5 1.1e-10 41.0 1.5 1.5 1 0 0 1 1 1 1 WH2 motif LRR_4 PF12799.7 EGG21977.1 - 7.8 7.1 15.7 19 5.8 0.7 5.4 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) DUF758 PF05527.11 EGG21978.1 - 2e-38 132.2 1.8 3e-38 131.6 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF758) PH PF00169.29 EGG21978.1 - 5.5e-07 30.1 0.1 1.1e-06 29.1 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EGG21978.1 - 0.011 16.1 0.4 0.28 11.5 0.4 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain p450 PF00067.22 EGG21978.1 - 0.013 14.3 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 BORCS7 PF16088.5 EGG21978.1 - 0.047 14.0 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 RsgA_GTPase PF03193.16 EGG21978.1 - 0.051 13.5 0.6 0.11 12.4 0.4 1.6 1 1 0 1 1 1 0 RsgA GTPase Ribosomal_S20p PF01649.18 EGG21978.1 - 0.059 14.0 1.9 0.16 12.6 1.9 1.7 1 0 0 1 1 1 0 Ribosomal protein S20 UbiA PF01040.18 EGG21979.1 - 2.8e-16 59.6 8.5 3.3e-16 59.3 8.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family UbiA PF01040.18 EGG21981.1 - 1.5e-12 47.4 10.0 2.3e-12 46.8 10.0 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family 4HBT PF03061.22 EGG21981.1 - 0.011 16.1 0.0 0.38 11.1 0.0 2.5 1 1 1 2 2 2 0 Thioesterase superfamily Helicase_PWI PF18149.1 EGG21981.1 - 0.046 13.9 0.3 0.11 12.7 0.3 1.6 1 0 0 1 1 1 0 N-terminal helicase PWI domain UbiA PF01040.18 EGG21982.1 - 0.024 13.9 7.3 0.011 15.0 3.4 2.2 1 1 2 3 3 3 0 UbiA prenyltransferase family DUF5122 PF17164.4 EGG21983.1 - 0.0013 19.0 3.0 0.0075 16.5 1.2 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5122) beta-propeller La PF05383.17 EGG21984.1 - 1.5e-09 37.7 0.0 4.9e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 La domain MIG-14_Wnt-bd PF06664.12 EGG21985.1 - 1.9e-62 211.2 45.4 1.9e-62 211.2 45.4 2.1 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion COX8 PF02285.15 EGG21985.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.7 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIII KleE PF17394.2 EGG21985.1 - 8.5 6.6 9.9 3.3 8.0 5.9 2.3 1 1 1 2 2 2 0 Uncharacterized KleE stable inheritance protein AAA_16 PF13191.6 EGG21986.1 - 2.8e-08 34.3 0.0 6.9e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG21986.1 - 2.8e-06 27.7 0.0 8.4e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EGG21986.1 - 0.00025 21.0 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EGG21986.1 - 0.0059 16.2 0.0 0.033 13.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain DAP3 PF10236.9 EGG21986.1 - 0.013 14.6 0.4 0.03 13.5 0.1 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 EGG21986.1 - 0.02 14.7 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EGG21986.1 - 0.022 15.2 0.1 0.13 12.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGG21986.1 - 0.027 14.7 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGG21986.1 - 0.028 14.4 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ESAG1 PF03238.13 EGG21986.1 - 0.056 12.9 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 ESAG protein ATPase PF06745.13 EGG21986.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 EGG21986.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 EGG21986.1 - 0.12 12.1 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EGG21986.1 - 0.13 11.9 0.0 0.37 10.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 EGG21987.1 - 2.7e-41 141.7 4.6 5.7e-21 75.1 1.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG21987.1 - 3.4e-13 49.5 4.7 1e-10 41.3 0.6 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Ndr PF03096.14 EGG21989.1 - 1.9e-73 246.6 0.1 2.3e-73 246.4 0.1 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 EGG21989.1 - 5.3e-06 26.3 0.0 0.00035 20.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG21989.1 - 0.00029 20.2 0.0 0.00042 19.7 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUSP PF06337.12 EGG21989.1 - 0.13 12.9 1.2 0.3 11.7 0.6 1.9 2 0 0 2 2 2 0 DUSP domain SLBP_RNA_bind PF15247.6 EGG21991.1 - 2e-27 95.1 4.2 2e-27 95.1 4.2 2.0 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain KinB_sensor PF16767.5 EGG21991.1 - 0.099 13.1 1.9 0.12 12.8 0.1 1.9 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB NOA36 PF06524.12 EGG21991.1 - 2.7 7.2 6.3 4 6.7 6.3 1.2 1 0 0 1 1 1 0 NOA36 protein DLH PF01738.18 EGG21992.1 - 2.1e-06 27.5 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EGG21992.1 - 0.00049 20.8 0.0 0.00064 20.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGG21992.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGG21992.1 - 0.008 15.7 0.1 0.63 9.5 0.0 2.2 1 1 0 2 2 2 1 Prolyl oligopeptidase family DUF3446 PF11928.8 EGG21992.1 - 0.16 12.3 14.3 1.7 9.0 2.4 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Hydrolase_4 PF12146.8 EGG21992.1 - 0.17 11.1 0.1 2.2 7.5 0.0 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 HEAT PF02985.22 EGG21993.1 - 4.3e-06 26.5 0.2 0.056 13.7 0.1 3.9 3 0 0 3 3 3 2 HEAT repeat Vac14_Fab1_bd PF12755.7 EGG21993.1 - 0.0015 19.1 0.1 0.011 16.3 0.1 2.7 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 EGG21993.1 - 0.016 15.0 0.5 0.73 9.5 1.1 2.7 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis DCB PF16213.5 EGG21993.1 - 0.049 13.3 5.7 0.023 14.3 1.5 2.6 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 TAF6_C PF07571.13 EGG21993.1 - 0.06 13.7 0.0 3.5 8.0 0.0 2.9 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Tti2 PF10521.9 EGG21993.1 - 0.075 12.6 3.0 0.18 11.3 0.1 2.9 2 1 2 4 4 4 0 Tti2 family RTP1_C1 PF10363.9 EGG21993.1 - 0.098 12.8 0.2 1.8 8.8 0.0 3.1 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 ERK-JNK_inhib PF15002.6 EGG21993.1 - 0.14 11.9 2.2 2.1 8.0 0.0 3.2 3 0 0 3 3 3 0 ERK and JNK pathways, inhibitor Vac14_Fab1_bd PF12755.7 EGG21994.1 - 5.4e-06 26.9 0.3 4.1e-05 24.1 0.3 2.6 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGG21994.1 - 0.00019 21.4 5.0 22 5.6 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat Tti2 PF10521.9 EGG21994.1 - 0.00021 20.9 0.8 0.0076 15.8 0.1 3.3 3 1 0 3 3 3 1 Tti2 family HEAT_2 PF13646.6 EGG21994.1 - 0.00063 20.1 0.1 1.1 9.6 0.0 4.0 3 1 0 3 3 3 1 HEAT repeats CLASP_N PF12348.8 EGG21994.1 - 0.0096 15.5 6.0 0.17 11.4 0.0 3.7 3 1 1 4 4 4 1 CLASP N terminal Tho2 PF11262.8 EGG21994.1 - 0.019 14.1 4.3 0.072 12.3 0.1 2.4 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 HEAT_EZ PF13513.6 EGG21994.1 - 0.032 14.7 0.0 25 5.5 0.0 3.8 4 1 1 5 5 5 0 HEAT-like repeat BcrAD_BadFG PF01869.20 EGG21994.1 - 0.079 12.4 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF3447 PF11929.8 EGG21995.1 - 0.4 10.7 4.8 1.1 9.3 0.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) Mod_r PF07200.13 EGG21996.1 - 0.002 18.2 21.8 0.0023 18.1 21.8 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Seryl_tRNA_N PF02403.22 EGG21996.1 - 0.0026 18.0 21.7 0.0031 17.7 21.7 1.1 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Phage_GPO PF05929.11 EGG21996.1 - 0.039 13.6 14.1 0.044 13.4 14.1 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Cauli_AT PF03233.13 EGG21996.1 - 0.11 12.4 14.7 0.14 12.1 14.7 1.1 1 0 0 1 1 1 0 Aphid transmission protein FAM76 PF16046.5 EGG21996.1 - 0.12 11.7 16.2 0.14 11.5 16.2 1.0 1 0 0 1 1 1 0 FAM76 protein Golgin_A5 PF09787.9 EGG21996.1 - 0.14 11.6 22.6 0.16 11.4 22.6 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 HMMR_N PF15905.5 EGG21996.1 - 0.23 10.9 23.8 0.27 10.6 23.8 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Autophagy_N PF03986.13 EGG21996.1 - 0.37 10.7 11.2 0.46 10.4 11.2 1.0 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain TMPIT PF07851.13 EGG21996.1 - 0.4 9.9 16.3 0.45 9.7 16.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 EGG21996.1 - 0.41 10.7 26.9 0.53 10.4 26.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 EGG21996.1 - 0.5 8.9 18.2 0.55 8.8 18.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A GUB_WAK_bind PF13947.6 EGG21996.1 - 0.6 10.9 4.3 0.68 10.7 4.3 1.1 1 0 0 1 1 1 0 Wall-associated receptor kinase galacturonan-binding YabA PF06156.13 EGG21996.1 - 0.91 10.2 18.7 1.2 9.8 18.7 1.1 1 0 0 1 1 1 0 Initiation control protein YabA FAM60A PF15396.6 EGG21996.1 - 1.1 9.2 9.6 1.3 9.0 9.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A V_ATPase_I PF01496.19 EGG21996.1 - 1.3 6.9 14.6 1.4 6.7 14.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tho2 PF11262.8 EGG21996.1 - 1.4 8.0 14.4 1.5 7.9 14.4 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Mgr1 PF08602.10 EGG21996.1 - 1.5 7.6 11.0 1.6 7.5 11.0 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit HSP70 PF00012.20 EGG21996.1 - 1.6 6.9 13.3 1.6 6.8 13.3 1.0 1 0 0 1 1 1 0 Hsp70 protein Exonuc_VII_L PF02601.15 EGG21996.1 - 1.9 8.0 15.3 2.2 7.8 15.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 EGG21996.1 - 2 7.5 23.8 2.4 7.2 23.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 THOC7 PF05615.13 EGG21996.1 - 2.6 8.3 23.6 3.6 7.9 23.6 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 HemX PF04375.14 EGG21996.1 - 2.7 7.2 30.9 3.2 7.0 30.6 1.3 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Kei1 PF08552.11 EGG21996.1 - 3.3 7.5 4.8 4.2 7.2 4.8 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TMF_DNA_bd PF12329.8 EGG21996.1 - 4 7.5 26.6 5.1 7.2 14.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cnn_1N PF07989.11 EGG21996.1 - 4.8 7.4 25.7 3.2 8.0 7.5 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 MCU PF04678.13 EGG21996.1 - 6.6 6.8 9.4 10 6.2 9.4 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Cellulose_synt PF03552.14 EGG21996.1 - 7.8 4.9 7.6 8.1 4.8 7.6 1.0 1 0 0 1 1 1 0 Cellulose synthase CDC45 PF02724.14 EGG21997.1 - 0.12 10.6 7.1 0.15 10.3 7.1 1.2 1 0 0 1 1 1 0 CDC45-like protein RIO1 PF01163.22 EGG21998.1 - 1.3e-76 256.4 0.0 8.3e-76 253.8 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EGG21998.1 - 0.00013 20.9 2.8 0.00022 20.1 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EGG21998.1 - 0.013 14.9 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.14 EGG21998.1 - 0.041 13.2 0.2 2.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG21998.1 - 0.1 12.5 0.0 5.1 6.9 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.7 EGG22000.1 - 2.7e-19 69.6 1.3 9.8e-06 26.1 0.0 6.7 4 1 4 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22000.1 - 2.7e-11 43.7 5.1 0.005 17.4 0.0 8.8 7 3 3 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22000.1 - 2.3e-08 33.7 1.6 7.9 7.4 0.0 10.1 14 0 0 14 14 14 2 Ankyrin repeat Ank_5 PF13857.6 EGG22000.1 - 4.4e-05 23.7 0.3 6.1 7.3 0.0 6.9 6 1 1 7 7 7 1 Ankyrin repeats (many copies) Ank PF00023.30 EGG22000.1 - 0.0045 17.4 3.3 0.62 10.6 0.4 5.1 4 2 0 4 4 4 1 Ankyrin repeat EF-hand_1 PF00036.32 EGG22002.1 - 3.5e-08 32.4 0.0 0.0011 18.4 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGG22002.1 - 8.6e-07 28.4 0.0 0.0031 17.3 0.0 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGG22002.1 - 3.2e-05 24.3 0.0 0.00014 22.2 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGG22002.1 - 0.00055 19.7 0.2 0.49 10.3 0.0 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG22002.1 - 0.033 13.7 0.0 1.9 8.1 0.0 2.6 2 0 0 2 2 2 0 EF hand DUF4485 PF14846.6 EGG22002.1 - 0.19 11.8 1.5 7.1 6.7 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4485) Gly-zipper_OmpA PF13436.6 EGG22002.1 - 9.6 6.1 8.7 0.94 9.3 0.8 2.5 1 1 2 3 3 3 0 Glycine-zipper domain SCO1-SenC PF02630.14 EGG22003.1 - 9.1e-46 155.1 0.0 1.5e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 EGG22003.1 - 0.004 17.4 0.1 0.013 15.8 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like SARAF PF06682.12 EGG22003.1 - 0.01 15.5 0.1 0.015 15.0 0.1 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4366 PF14283.6 EGG22003.1 - 0.016 15.2 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) AhpC-TSA PF00578.21 EGG22003.1 - 0.027 14.4 0.0 0.058 13.3 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family CrgA PF06781.12 EGG22003.1 - 0.035 14.1 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Cell division protein CrgA TMEM223 PF14640.6 EGG22003.1 - 0.099 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 223 Acetyltransf_7 PF13508.7 EGG22007.1 - 5.3e-10 39.6 0.0 8.1e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG22007.1 - 3.2e-09 37.0 0.0 4.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG22007.1 - 8.8e-08 32.1 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGG22007.1 - 6.1e-05 23.1 0.1 0.00013 22.0 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG22007.1 - 0.0029 17.6 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGG22007.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Peptidase_S49 PF01343.18 EGG22009.1 - 5e-67 224.6 0.3 3.6e-40 137.4 0.1 2.5 2 0 0 2 2 2 2 Peptidase family S49 SDH_sah PF01972.16 EGG22009.1 - 1.9e-05 23.8 0.1 1.9e-05 23.8 0.1 1.5 2 0 0 2 2 2 1 Serine dehydrogenase proteinase CLP_protease PF00574.23 EGG22009.1 - 3.1e-05 23.9 0.8 7.5e-05 22.7 0.3 1.8 2 0 0 2 2 2 1 Clp protease GGA_N-GAT PF18308.1 EGG22009.1 - 0.055 13.1 0.3 0.13 11.9 0.3 1.6 1 0 0 1 1 1 0 GGA N-GAT domain Pkinase PF00069.25 EGG22010.1 - 6e-73 245.4 0.0 9.7e-73 244.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG22010.1 - 3.1e-41 141.4 0.0 4.9e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG22010.1 - 0.018 14.9 0.0 0.07 13.0 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG22010.1 - 0.046 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RRM_1 PF00076.22 EGG22012.1 - 6.2e-15 54.8 0.0 1e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PA26 PF04636.13 EGG22012.1 - 0.22 10.4 2.2 0.25 10.2 2.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) V_ATPase_I PF01496.19 EGG22012.1 - 0.48 8.3 4.3 0.56 8.1 4.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cauli_AT PF03233.13 EGG22012.1 - 0.75 9.7 5.1 1.2 9.0 5.1 1.3 1 0 0 1 1 1 0 Aphid transmission protein RhoGAP PF00620.27 EGG22013.1 - 4.4e-32 111.0 0.1 6e-29 100.8 0.0 3.2 2 1 0 2 2 2 1 RhoGAP domain LRR_4 PF12799.7 EGG22013.1 - 2.9e-08 33.9 13.4 0.0048 17.3 0.4 5.9 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG22013.1 - 3.4e-07 29.9 5.2 0.019 14.7 0.1 4.3 4 0 0 4 4 4 2 Leucine rich repeat EGF_2 PF07974.13 EGG22013.1 - 0.00084 19.7 12.8 0.0018 18.6 12.8 1.6 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG22013.1 - 0.0031 17.5 9.5 0.0031 17.5 9.5 1.8 2 0 0 2 2 1 1 Tenascin EGF domain EGF PF00008.27 EGG22013.1 - 0.0087 16.3 4.0 0.02 15.2 4.0 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 EGG22013.1 - 0.0099 16.5 8.6 0.029 15.0 8.6 1.9 1 0 0 1 1 1 1 Human growth factor-like EGF zf-C4H2 PF10146.9 EGG22013.1 - 0.013 15.8 0.4 0.013 15.8 0.4 2.8 2 1 0 2 2 1 0 Zinc finger-containing protein I-EGF_1 PF18372.1 EGG22013.1 - 0.034 14.3 13.5 0.019 15.0 6.1 2.5 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 EB PF01683.18 EGG22013.1 - 0.043 14.1 3.5 0.094 13.0 3.5 1.5 1 0 0 1 1 1 0 EB module DUF948 PF06103.11 EGG22013.1 - 0.06 13.6 4.6 1.9 8.8 0.2 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2096 PF09869.9 EGG22013.1 - 0.33 11.0 4.3 0.22 11.6 1.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) HD_3 PF13023.6 EGG22013.1 - 0.43 10.5 2.1 5.7 6.8 0.1 2.6 3 0 0 3 3 3 0 HD domain Toxin_5 PF05294.13 EGG22013.1 - 0.6 10.6 3.7 1.2 9.6 3.7 1.6 1 0 0 1 1 1 0 Scorpion short toxin MATH PF00917.26 EGG22014.1 - 2.5e-05 24.4 0.0 2.7e-05 24.3 0.0 1.0 1 0 0 1 1 1 1 MATH domain Sina PF03145.16 EGG22015.1 - 2.7e-08 34.0 8.9 2.6e-05 24.3 3.8 2.7 1 1 1 2 2 2 2 Seven in absentia protein family zf-C3HC4_3 PF13920.6 EGG22015.1 - 0.00033 20.5 6.7 0.00033 20.5 6.7 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 EGG22015.1 - 0.00039 21.1 8.7 0.00039 21.1 8.7 3.1 2 1 1 3 3 3 1 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EGG22015.1 - 0.021 15.3 5.2 0.021 15.3 5.2 2.6 2 2 0 2 2 2 0 TRAF-like zinc-finger DUF4375 PF14300.6 EGG22015.1 - 0.057 13.7 0.4 0.14 12.4 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) zf-C2H2_9 PF16293.5 EGG22015.1 - 0.058 13.3 0.7 2.6 8.0 0.1 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-RING_5 PF14634.6 EGG22015.1 - 4.2 7.4 24.0 3.3 7.7 8.8 3.0 2 2 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 EGG22015.1 - 5.2 7.5 21.1 0.073 13.4 8.5 3.0 2 1 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 EGG22015.1 - 6.2 6.8 25.2 0.097 12.5 9.4 3.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) BB_PF PF18063.1 EGG22016.1 - 3.3e-07 30.1 0.8 0.00045 19.9 0.2 2.9 2 1 0 2 2 2 2 Beta barrel Pore-forming domain Sina PF03145.16 EGG22017.1 - 1.9e-07 31.2 4.1 0.0042 17.1 0.5 2.4 1 1 1 2 2 2 2 Seven in absentia protein family zf-TRAF PF02176.18 EGG22017.1 - 3.7e-07 30.7 10.8 0.00014 22.5 3.1 3.2 3 1 1 4 4 4 2 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGG22017.1 - 0.00013 21.8 4.8 0.00013 21.8 4.8 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG22017.1 - 0.00084 19.6 6.4 0.00084 19.6 6.4 3.2 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 EGG22017.1 - 0.0032 17.3 7.2 0.0032 17.3 7.2 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG22017.1 - 0.0038 17.0 7.9 0.0038 17.0 7.9 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EGG22017.1 - 0.028 14.9 5.0 0.028 14.9 5.0 2.6 1 1 0 2 2 2 0 TRAF-like zinc-finger zf-RING_UBOX PF13445.6 EGG22017.1 - 0.029 14.4 4.4 0.029 14.4 4.4 2.7 4 0 0 4 4 4 0 RING-type zinc-finger zf_C2HC_14 PF18574.1 EGG22017.1 - 0.19 11.6 0.3 0.19 11.6 0.3 3.7 4 0 0 4 4 4 0 C2HC Zing finger domain zf-RING_10 PF16685.5 EGG22017.1 - 1.9 8.7 11.0 0.1 12.7 5.2 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EGG22017.1 - 6.3 7.0 14.4 0.34 11.1 7.8 2.5 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-TRAF PF02176.18 EGG22018.1 - 3.4e-07 30.8 10.9 3.4e-07 30.8 10.9 3.1 2 1 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGG22018.1 - 0.0001 22.1 7.8 0.0001 22.1 7.8 2.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EGG22018.1 - 0.031 14.7 5.9 0.031 14.7 5.9 3.6 2 1 2 4 4 4 0 TRAF-like zinc-finger zf-RING_UBOX PF13445.6 EGG22018.1 - 0.23 11.5 13.6 0.12 12.4 9.0 2.8 2 0 0 2 2 2 0 RING-type zinc-finger TSC22 PF01166.18 EGG22018.1 - 0.36 11.2 2.6 11 6.4 3.4 2.8 1 1 1 2 2 2 0 TSC-22/dip/bun family TRAF_BIRC3_bd PF16673.5 EGG22018.1 - 1.4 8.8 6.0 1.9 8.3 0.8 2.7 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF3847 PF12958.7 EGG22018.1 - 2.8 8.1 7.4 1.1 9.5 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) zf-C3HC4_2 PF13923.6 EGG22018.1 - 3.9 7.4 22.6 0.12 12.3 10.6 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF16 PF01519.16 EGG22018.1 - 5.4 7.6 10.9 5.9 7.4 9.0 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 Sina PF03145.16 EGG22019.1 - 1.9e-13 50.9 24.0 8.2e-05 22.6 2.4 4.6 2 2 2 4 4 4 4 Seven in absentia protein family zf-C3HC4_3 PF13920.6 EGG22019.1 - 1.8e-07 30.9 14.4 4.8e-05 23.1 5.0 4.3 4 2 0 4 4 2 2 Zinc finger, C3HC4 type (RING finger) Apolipoprotein PF01442.18 EGG22019.1 - 3.6e-06 27.0 4.0 0.0023 17.8 0.3 2.2 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain zf-RING_2 PF13639.6 EGG22019.1 - 1.5e-05 25.3 15.2 0.00029 21.1 6.1 4.1 4 2 0 4 4 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 EGG22019.1 - 0.0016 18.2 18.0 0.0026 17.6 8.0 5.0 4 2 1 5 5 4 2 Zinc finger, C3HC4 type (RING finger) FapA PF03961.13 EGG22019.1 - 0.0033 16.1 20.1 0.056 12.1 9.4 2.1 2 0 0 2 2 2 2 Flagellar Assembly Protein A zf-RING_UBOX PF13445.6 EGG22019.1 - 0.0035 17.3 4.8 0.0035 17.3 4.8 4.2 4 1 0 4 4 3 2 RING-type zinc-finger Prok-RING_4 PF14447.6 EGG22019.1 - 0.0069 16.2 1.1 0.0069 16.2 1.1 4.5 5 0 0 5 5 4 2 Prokaryotic RING finger family 4 zf-TRAF PF02176.18 EGG22019.1 - 0.0083 16.8 7.2 0.0083 16.8 7.2 5.2 5 1 0 5 5 2 1 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EGG22019.1 - 0.0084 16.6 2.2 0.0084 16.6 2.2 4.4 4 0 0 4 4 3 2 TRAF-like zinc-finger zf-RING_4 PF14570.6 EGG22019.1 - 0.01 15.6 1.0 0.01 15.6 1.0 4.4 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain DUF2203 PF09969.9 EGG22019.1 - 0.036 14.8 0.5 0.036 14.8 0.5 3.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF735 PF05246.11 EGG22019.1 - 0.051 13.5 3.7 0.85 9.5 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF735) zf-U11-48K PF05253.12 EGG22019.1 - 0.061 13.3 0.4 33 4.5 0.0 4.1 3 0 0 3 3 2 0 U11-48K-like CHHC zinc finger HXXSHH PF07586.11 EGG22019.1 - 0.064 12.8 1.4 0.13 11.8 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) UBZ_FAAP20 PF15750.5 EGG22019.1 - 0.089 12.8 2.8 19 5.3 0.0 3.9 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger F-box_4 PF15966.5 EGG22019.1 - 0.25 11.2 6.9 2.5 8.0 0.6 3.8 3 1 0 3 3 3 0 F-box zf_Rg PF17915.1 EGG22019.1 - 0.57 9.6 4.6 1.8 8.0 0.0 3.2 3 0 0 3 3 3 0 Reverse gyrase zinc finger Exonuc_VII_L PF02601.15 EGG22019.1 - 0.72 9.4 14.6 0.99 8.9 5.2 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit zf-C3HC4 PF00097.25 EGG22019.1 - 0.96 9.4 33.7 0.026 14.4 7.0 4.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 EGG22019.1 - 1.4 8.6 8.5 8.5 6.1 0.4 3.3 2 1 0 2 2 2 0 P-11 zinc finger YtxH PF12732.7 EGG22019.1 - 2.9 8.5 11.3 9.9 6.8 0.1 3.8 3 1 0 3 3 3 0 YtxH-like protein zf-RING_5 PF14634.6 EGG22019.1 - 3.2 7.8 44.9 0.039 13.9 3.7 4.9 4 0 0 4 4 4 0 zinc-RING finger domain Seryl_tRNA_N PF02403.22 EGG22019.1 - 6 7.1 16.9 0.034 14.4 2.5 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF445 PF04286.12 EGG22019.1 - 7.4 6.3 16.9 2.5 7.8 7.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Sina PF03145.16 EGG22020.1 - 2.7e-08 34.0 7.7 2.3e-05 24.5 1.2 2.6 1 1 1 2 2 2 2 Seven in absentia protein family zf-C3HC4_3 PF13920.6 EGG22020.1 - 5.1e-06 26.2 5.9 5.1e-06 26.2 5.9 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG22020.1 - 0.00017 21.8 7.4 0.00017 21.8 7.4 2.6 2 1 0 2 2 1 1 Ring finger domain zf-TRAF PF02176.18 EGG22020.1 - 0.0021 18.7 5.2 0.0021 18.7 5.2 3.0 3 1 0 3 3 2 1 TRAF-type zinc finger Apolipoprotein PF01442.18 EGG22020.1 - 0.0034 17.3 2.1 0.0093 15.9 2.1 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.15 EGG22020.1 - 0.004 16.8 0.3 0.0051 16.4 0.3 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit zf-RING_UBOX PF13445.6 EGG22020.1 - 0.0068 16.4 5.8 0.0068 16.4 5.8 2.3 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG22020.1 - 0.007 16.2 9.1 0.007 16.2 9.1 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EGG22020.1 - 0.0079 16.6 5.6 0.0079 16.6 5.6 2.3 2 0 0 2 2 1 1 TRAF-like zinc-finger Baculo_PEP_C PF04513.12 EGG22020.1 - 0.011 15.8 2.6 0.02 14.9 2.6 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4795 PF16043.5 EGG22020.1 - 0.012 15.2 4.1 0.019 14.6 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) zf-C3HC4 PF00097.25 EGG22020.1 - 0.013 15.4 8.3 0.013 15.4 8.3 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) OmpH PF03938.14 EGG22020.1 - 0.02 15.2 7.1 0.033 14.5 7.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FapA PF03961.13 EGG22020.1 - 0.037 12.7 5.2 0.051 12.2 5.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A YtxH PF12732.7 EGG22020.1 - 0.037 14.6 7.4 2.5 8.7 1.0 2.6 1 1 1 2 2 2 0 YtxH-like protein PNMA PF14893.6 EGG22020.1 - 0.049 13.0 0.7 0.075 12.4 0.7 1.2 1 0 0 1 1 1 0 PNMA MADF_DNA_bdg PF10545.9 EGG22020.1 - 0.14 12.5 2.9 1.3 9.4 0.1 2.6 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DASH_Ask1 PF08655.10 EGG22020.1 - 0.15 12.0 2.8 0.37 10.7 2.8 1.7 1 0 0 1 1 1 0 DASH complex subunit Ask1 YlqD PF11068.8 EGG22020.1 - 0.16 12.3 4.9 0.35 11.2 4.9 1.6 1 0 0 1 1 1 0 YlqD protein DUF883 PF05957.13 EGG22020.1 - 0.2 12.3 0.4 0.38 11.4 0.4 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Prok-RING_4 PF14447.6 EGG22020.1 - 0.25 11.2 12.3 0.044 13.6 6.1 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 ApoO PF09769.9 EGG22020.1 - 0.3 11.0 1.8 1.1 9.2 0.8 2.0 1 1 1 2 2 2 0 Apolipoprotein O PTPlike_phytase PF14566.6 EGG22020.1 - 0.45 10.6 3.0 0.92 9.6 3.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate zf-RAG1 PF10426.9 EGG22020.1 - 0.47 10.6 7.0 1.5 9.0 0.7 3.3 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain DUF1640 PF07798.11 EGG22020.1 - 0.51 10.4 10.1 0.84 9.7 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FAM184 PF15665.5 EGG22020.1 - 0.82 9.4 11.6 5.4 6.7 10.4 2.1 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B DUF4407 PF14362.6 EGG22020.1 - 2.2 7.5 4.2 3.1 7.1 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-RING_4 PF14570.6 EGG22020.1 - 2.5 8.0 12.0 0.044 13.6 3.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EGG22020.1 - 3.8 7.6 21.1 0.13 12.2 8.3 2.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_6 PF14835.6 EGG22020.1 - 7.2 6.6 8.7 1.5 8.8 4.9 1.8 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Sina PF03145.16 EGG22021.1 - 3.7e-08 33.6 5.4 1e-07 32.1 5.2 1.9 1 1 0 1 1 1 1 Seven in absentia protein family zf-RING_2 PF13639.6 EGG22021.1 - 7.8e-06 26.1 7.4 2.3e-05 24.6 7.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGG22021.1 - 8.8e-06 25.5 5.8 8.8e-06 25.5 5.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG22021.1 - 8.1e-05 22.4 8.8 0.00021 21.1 8.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG22021.1 - 9.2e-05 22.4 6.1 0.00026 20.9 6.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG22021.1 - 0.0016 18.2 7.9 0.0052 16.6 7.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FlxA PF14282.6 EGG22021.1 - 0.0052 16.7 8.3 0.014 15.4 8.3 1.7 1 0 0 1 1 1 1 FlxA-like protein Prok-RING_4 PF14447.6 EGG22021.1 - 0.013 15.3 2.2 0.013 15.3 2.2 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Thioredoxin_8 PF13905.6 EGG22021.1 - 0.016 15.5 1.4 0.05 13.9 1.4 1.9 1 0 0 1 1 1 0 Thioredoxin-like zf-C3HC4_4 PF15227.6 EGG22021.1 - 0.017 15.3 9.0 0.057 13.6 9.0 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-TRAF PF02176.18 EGG22021.1 - 0.064 14.0 1.1 0.064 14.0 1.1 2.6 2 1 0 2 2 1 0 TRAF-type zinc finger HD_assoc PF13286.6 EGG22021.1 - 0.07 13.7 1.5 0.17 12.5 0.9 1.9 1 1 1 2 2 2 0 Phosphohydrolase-associated domain DUF5513 PF17632.2 EGG22021.1 - 0.14 12.6 0.8 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5513) zf-RING_5 PF14634.6 EGG22021.1 - 0.17 11.9 9.8 1.4 8.9 10.1 2.5 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 EGG22021.1 - 0.23 11.3 9.9 0.038 13.8 4.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RasGAP_C PF03836.15 EGG22021.1 - 0.81 9.8 10.5 0.47 10.6 5.1 2.3 1 1 1 2 2 2 0 RasGAP C-terminus zf-MIZ PF02891.20 EGG22021.1 - 3.2 7.6 7.4 14 5.5 7.4 2.2 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_10 PF16685.5 EGG22021.1 - 9.3 6.5 11.9 1.1 9.5 6.6 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Sina PF03145.16 EGG22022.1 - 1e-14 54.9 24.9 1.2e-06 28.6 3.6 4.6 1 1 2 4 4 4 4 Seven in absentia protein family zf-TRAF PF02176.18 EGG22022.1 - 7.6e-06 26.5 21.2 0.00062 20.4 6.1 4.5 3 2 1 4 4 4 2 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EGG22022.1 - 9.7e-05 22.8 8.9 9.7e-05 22.8 8.9 3.4 3 1 0 3 3 3 2 TRAF-like zinc-finger zf-C3HC4_2 PF13923.6 EGG22022.1 - 0.0013 18.5 5.8 0.0013 18.5 5.8 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FliD_C PF07195.12 EGG22022.1 - 0.003 17.0 5.1 0.24 10.8 1.3 2.3 2 0 0 2 2 2 2 Flagellar hook-associated protein 2 C-terminus zf-C3HC4 PF00097.25 EGG22022.1 - 0.0033 17.3 4.9 0.0033 17.3 4.9 4.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FlaC_arch PF05377.11 EGG22022.1 - 0.011 16.1 0.7 0.011 16.1 0.7 3.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Pox_A_type_inc PF04508.12 EGG22022.1 - 0.047 13.6 12.3 0.091 12.7 2.4 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF87 PF01935.17 EGG22022.1 - 0.33 11.0 7.0 0.78 9.8 2.3 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain ING PF12998.7 EGG22022.1 - 0.52 10.9 12.3 1.3 9.6 0.6 3.3 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding zf-C2H2_9 PF16293.5 EGG22022.1 - 1.7 8.5 9.8 0.51 10.2 0.4 4.2 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) Med4 PF10018.9 EGG22022.1 - 1.7 8.3 20.4 0.022 14.4 2.7 2.8 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 LPD39 PF18858.1 EGG22022.1 - 5 7.2 6.8 0.85 9.7 1.6 2.2 2 1 1 3 3 3 0 Large polyvalent protein associated domain 39 MetOD2 PF18548.1 EGG22022.1 - 5.3 7.2 10.2 0.74 10.0 1.7 2.6 2 0 0 2 2 2 0 Metanogen output domain 2 Bcr-Abl_Oligo PF09036.10 EGG22022.1 - 5.8 7.0 10.2 8.1 6.5 1.8 3.3 3 1 1 4 4 3 0 Bcr-Abl oncoprotein oligomerisation domain MATH PF00917.26 EGG22023.1 - 1.6e-07 31.5 0.9 3e-07 30.6 0.9 1.5 1 0 0 1 1 1 1 MATH domain Sina PF03145.16 EGG22023.1 - 0.00023 21.2 0.8 0.00023 21.2 0.8 1.9 3 0 0 3 3 3 1 Seven in absentia protein family zf-TRAF PF02176.18 EGG22023.1 - 0.00082 20.0 4.7 0.0029 18.2 1.8 2.9 3 0 0 3 3 3 1 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EGG22023.1 - 0.016 15.6 1.8 0.022 15.2 0.2 2.0 2 0 0 2 2 2 0 TRAF-like zinc-finger GAGA PF09237.11 EGG22023.1 - 0.017 14.9 6.5 0.11 12.3 0.2 2.4 1 1 1 2 2 2 0 GAGA factor zinc_ribbon_9 PF14369.6 EGG22023.1 - 0.2 11.9 4.0 21 5.5 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon DNase_II PF03265.15 EGG22024.1 - 9.9e-16 57.9 0.9 9.9e-16 57.9 0.9 2.5 4 0 0 4 4 4 1 Deoxyribonuclease II Ank_2 PF12796.7 EGG22025.1 - 0.0016 19.0 0.2 11 6.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG22025.1 - 0.0022 18.3 5.7 1 10.1 0.1 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 EGG22025.1 - 0.051 14.2 2.2 7.9 7.2 0.1 4.2 4 1 0 4 4 4 0 Ankyrin repeats (many copies) BB_PF PF18063.1 EGG22026.1 - 1.1e-81 273.4 2.2 6e-49 166.5 0.6 2.5 2 1 0 2 2 2 2 Beta barrel Pore-forming domain COX_ARM PF06481.14 EGG22026.1 - 0.11 12.4 0.6 22 5.1 0.0 2.6 2 0 0 2 2 2 0 COX Aromatic Rich Motif Ribosomal_L11_N PF03946.14 EGG22026.1 - 0.14 12.0 0.1 0.4 10.5 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain BB_PF PF18063.1 EGG22027.1 - 2.4e-35 122.0 0.1 6e-35 120.7 0.1 1.6 1 1 0 1 1 1 1 Beta barrel Pore-forming domain zf-C3HC4_3 PF13920.6 EGG22029.1 - 3.3e-07 30.1 4.5 3.3e-07 30.1 4.5 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 EGG22029.1 - 4.4e-07 30.0 6.4 7.1e-05 22.8 0.8 2.4 1 1 1 2 2 2 2 Seven in absentia protein family zf-RING_2 PF13639.6 EGG22029.1 - 1e-05 25.7 7.1 1e-05 25.7 7.1 3.1 3 1 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG22029.1 - 4.2e-05 23.5 5.7 4.2e-05 23.5 5.7 3.1 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG22029.1 - 6.9e-05 22.6 8.2 6.9e-05 22.6 8.2 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 EGG22029.1 - 0.0021 18.7 5.6 0.0021 18.7 5.6 3.2 2 1 1 3 3 3 1 TRAF-type zinc finger zf-C3HC4 PF00097.25 EGG22029.1 - 0.0032 17.3 6.9 0.0032 17.3 6.9 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EGG22029.1 - 0.017 14.9 4.0 0.017 14.9 4.0 2.7 2 2 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EGG22029.1 - 0.025 14.7 7.9 0.025 14.7 7.9 3.3 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGG22029.1 - 0.035 14.1 22.4 0.16 12.0 9.4 3.3 3 1 1 4 4 4 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGG22029.1 - 0.094 12.8 0.4 0.094 12.8 0.4 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.12 EGG22029.1 - 0.15 12.4 7.5 2.2 8.7 0.0 3.4 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 EGG22029.1 - 0.2 11.5 19.6 0.096 12.6 9.3 3.8 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 OHCU_decarbox PF09349.10 EGG22030.1 - 8.8e-41 140.0 0.2 2.2e-39 135.5 0.0 2.2 2 0 0 2 2 2 1 OHCU decarboxylase Amidohydro_1 PF01979.20 EGG22030.1 - 2.2e-28 99.6 0.0 2.9e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGG22030.1 - 8e-14 52.0 0.3 1.2e-10 41.5 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Swi5 PF07061.11 EGG22030.1 - 0.015 15.3 0.7 0.79 9.8 0.0 2.9 3 0 0 3 3 3 0 Swi5 DUF1878 PF08963.10 EGG22030.1 - 0.31 11.6 1.6 1.3 9.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) AP3D1 PF06375.11 EGG22031.1 - 0.00082 19.6 4.8 0.00082 19.6 4.8 1.5 2 0 0 2 2 2 1 AP-3 complex subunit delta-1 Cyclin_N PF00134.23 EGG22031.1 - 0.0046 16.7 0.1 0.0046 16.7 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain HGTP_anticodon2 PF12745.7 EGG22031.1 - 0.0073 15.9 5.5 0.016 14.7 5.5 1.5 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs DDHD PF02862.17 EGG22031.1 - 0.0085 16.3 0.4 0.011 16.0 0.4 1.1 1 0 0 1 1 1 1 DDHD domain DUF3525 PF12039.8 EGG22031.1 - 0.062 12.0 0.6 0.12 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3525) DUF1422 PF07226.11 EGG22031.1 - 0.11 12.6 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) MEIOC PF15189.6 EGG22031.1 - 0.15 11.7 7.0 0.24 11.0 7.0 1.3 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC DUF4500 PF14937.6 EGG22031.1 - 2.2 8.4 6.2 1.8 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) DUF4407 PF14362.6 EGG22031.1 - 4.6 6.5 7.0 6.3 6.1 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF202 PF02656.15 EGG22032.1 - 4.5e-15 55.8 0.5 7.3e-15 55.2 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Macoilin PF09726.9 EGG22032.1 - 7.2 5.0 19.6 8.1 4.9 19.6 1.0 1 0 0 1 1 1 0 Macoilin family DUF3430 PF11912.8 EGG22033.1 - 6.1e-06 26.4 13.7 6.1e-06 26.4 13.7 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3430) AIG1 PF04548.16 EGG22034.1 - 7.9 5.7 6.3 5.3 6.3 0.5 2.4 2 0 0 2 2 2 0 AIG1 family DUF2283 PF10049.9 EGG22036.1 - 0.0096 16.1 0.2 0.49 10.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2283) Ank_2 PF12796.7 EGG22037.1 - 2.1e-17 63.5 3.0 7.9e-08 32.8 0.2 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22037.1 - 2.8e-15 56.5 0.3 4.5e-07 30.3 0.1 5.4 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22037.1 - 2.3e-13 50.1 0.2 1.3e-05 25.3 0.1 5.1 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22037.1 - 9.1e-09 34.9 0.2 0.35 11.6 0.0 6.4 6 1 2 8 8 8 2 Ankyrin repeat Ank PF00023.30 EGG22037.1 - 0.055 14.0 0.1 1.3e+02 3.2 0.0 4.5 6 0 0 6 6 6 0 Ankyrin repeat DUF2967 PF11179.8 EGG22037.1 - 0.17 10.0 1.7 0.24 9.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) FlxA PF14282.6 EGG22037.1 - 0.17 11.9 12.9 0.3 11.1 12.9 1.3 1 0 0 1 1 1 0 FlxA-like protein Ras PF00071.22 EGG22038.1 - 1.4e-34 119.1 0.0 1.6e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG22038.1 - 9.8e-17 61.3 0.0 1.6e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG22038.1 - 0.017 14.5 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Dec-1 PF04624.14 EGG22038.1 - 0.27 11.1 0.7 0.61 10.0 0.7 1.5 1 0 0 1 1 1 0 Dec-1 repeat Ras PF00071.22 EGG22039.1 - 1.2e-20 73.8 0.3 1.7e-20 73.3 0.1 1.3 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGG22039.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG22039.1 - 0.017 14.5 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family PAP_assoc PF03828.19 EGG22039.1 - 0.19 12.0 0.6 0.57 10.4 0.0 2.1 3 0 0 3 3 3 0 Cid1 family poly A polymerase Pkinase PF00069.25 EGG22040.1 - 2e-60 204.4 0.1 7.3e-60 202.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG22040.1 - 7.6e-42 143.4 0.0 1.4e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG22040.1 - 0.0073 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like TSC22 PF01166.18 EGG22040.1 - 0.25 11.7 2.5 0.28 11.5 0.7 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 EGG22040.1 - 0.95 10.1 7.1 0.71 10.5 2.8 2.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF3430 PF11912.8 EGG22042.1 - 2.5e-09 37.5 7.4 2.5e-09 37.5 7.4 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3430) Ras PF00071.22 EGG22042.1 - 1.7e-08 34.2 0.0 4.9e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG22042.1 - 5.2e-05 23.5 0.0 0.0002 21.5 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG22042.1 - 0.15 11.5 0.3 2.2 7.7 0.0 2.7 2 1 0 2 2 2 0 ADP-ribosylation factor family DUF3430 PF11912.8 EGG22043.1 - 1.8e-09 38.0 0.1 1.8e-09 38.0 0.1 2.8 2 2 0 2 2 2 1 Protein of unknown function (DUF3430) SpoIIIAH PF12685.7 EGG22043.1 - 0.52 10.1 4.2 1 9.2 4.2 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein WD40 PF00400.32 EGG22044.1 - 4.1e-16 59.1 22.5 0.0018 19.0 0.2 9.5 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG22044.1 - 6e-08 32.9 0.0 3.2 8.1 0.0 6.4 7 1 1 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain FKBP_C PF00254.28 EGG22045.1 - 2.4e-18 66.3 0.0 5.6e-18 65.1 0.0 1.6 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_6 PF13405.6 EGG22046.1 - 0.00014 21.5 0.0 1.7 8.8 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EGG22046.1 - 0.0049 17.3 0.1 0.28 11.7 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGG22046.1 - 0.011 15.2 0.0 8.2 6.2 0.0 2.9 3 0 0 3 3 3 0 EF hand Nup84_Nup100 PF04121.13 EGG22047.1 - 1.8e-175 585.1 14.3 1.8e-175 585.1 14.3 2.0 2 0 0 2 2 2 1 Nuclear pore protein 84 / 107 Ank_2 PF12796.7 EGG22048.1 - 1.3e-31 109.0 8.8 1.9e-07 31.6 0.1 7.3 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22048.1 - 7.7e-24 83.4 3.7 0.047 14.0 0.0 11.7 7 3 4 11 11 11 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22048.1 - 2.5e-22 78.9 9.5 0.00017 22.1 0.1 9.3 6 2 3 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22048.1 - 1.2e-12 46.8 10.1 4.3 8.2 0.0 11.8 14 1 1 15 15 15 3 Ankyrin repeat SapB_2 PF03489.17 EGG22048.1 - 1.2e-07 31.6 0.1 4.9e-07 29.7 0.1 2.2 1 0 0 1 1 1 1 Saposin-like type B, region 2 Lipase_GDSL PF00657.22 EGG22048.1 - 2.6e-06 27.6 0.0 5.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ank PF00023.30 EGG22048.1 - 0.00012 22.4 4.8 44 4.8 0.0 7.7 6 3 3 9 9 9 0 Ankyrin repeat Cu-binding_MopE PF11617.8 EGG22048.1 - 0.033 14.3 4.5 0.033 14.3 2.5 2.1 2 0 0 2 2 2 0 Putative metal-binding motif SUB1_ProdP9 PF18213.1 EGG22048.1 - 0.093 12.6 0.9 2.2 8.2 0.1 3.0 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 Ank_2 PF12796.7 EGG22049.1 - 6.6e-50 167.6 18.9 3.4e-10 40.4 0.2 8.6 2 2 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22049.1 - 4.6e-41 138.7 19.5 5.9e-05 23.5 0.0 11.8 7 3 4 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22049.1 - 1.1e-38 130.7 16.8 0.0083 16.4 0.0 16.1 3 3 14 17 17 17 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22049.1 - 8.9e-29 96.3 6.6 0.43 11.3 0.0 16.1 16 1 1 17 17 17 7 Ankyrin repeat Ank PF00023.30 EGG22049.1 - 4.1e-12 46.0 10.1 22 5.7 0.0 13.4 10 3 1 11 11 11 1 Ankyrin repeat DUF5049 PF16468.5 EGG22049.1 - 1.3e-08 34.6 0.1 2.4 8.1 0.0 8.8 8 2 2 10 10 10 2 Domain of unknown function (DUF5049) CNOT1_HEAT PF16418.5 EGG22049.1 - 0.015 15.3 0.7 0.76 9.8 0.0 3.5 4 1 1 5 5 5 0 CCR4-NOT transcription complex subunit 1 HEAT repeat LRR_8 PF13855.6 EGG22050.1 - 0.19 11.5 3.9 23 4.8 0.3 4.2 3 2 2 5 5 5 0 Leucine rich repeat EGF_2 PF07974.13 EGG22051.1 - 0.023 15.1 7.8 0.06 13.7 7.8 1.7 1 0 0 1 1 1 0 EGF-like domain Cpn60_TCP1 PF00118.24 EGG22052.1 - 2.3e-86 290.4 14.8 3.4e-86 289.8 14.8 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_S39 PF02122.15 EGG22052.1 - 0.16 11.5 0.0 0.7 9.4 0.0 2.1 3 0 0 3 3 3 0 Peptidase S39 FtsK_gamma PF09397.10 EGG22052.1 - 0.57 10.0 2.3 0.98 9.3 0.1 2.5 3 0 0 3 3 3 0 Ftsk gamma domain WD40 PF00400.32 EGG22053.1 - 2.5e-46 154.7 26.8 2.9e-08 34.2 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG22053.1 - 1.3e-19 70.3 7.1 9.1e-05 22.7 0.2 6.3 1 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGG22053.1 - 0.00029 19.7 2.0 0.43 9.3 0.0 3.1 1 1 1 2 2 2 2 Nup133 N terminal like WD40_like PF17005.5 EGG22053.1 - 0.0011 18.4 0.0 0.26 10.6 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain EGF_2 PF07974.13 EGG22054.1 - 0.18 12.2 7.8 0.41 11.1 7.8 1.6 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.24 EGG22054.1 - 7.8 6.7 33.3 0.24 11.5 0.3 6.0 6 1 0 6 6 6 0 IPT/TIG domain Proteasome PF00227.26 EGG22055.1 - 4.2e-60 202.5 0.1 5.6e-60 202.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGG22055.1 - 3.2e-15 55.5 0.2 1e-14 53.9 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature EGF_2 PF07974.13 EGG22057.1 - 4 7.9 12.5 0.4 11.1 7.8 1.9 2 0 0 2 2 2 0 EGF-like domain Ribosomal_L30_N PF08079.12 EGG22058.1 - 6.9e-22 77.5 14.2 1.1e-21 76.8 14.2 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EGG22058.1 - 7.5e-21 73.8 1.5 7.5e-21 73.8 1.5 2.3 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF5435 PF17503.2 EGG22058.1 - 0.049 13.4 1.9 0.079 12.7 1.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Elong_Iki1 PF10483.9 EGG22059.1 - 1.1e-15 57.9 1.9 1.4e-12 47.8 1.9 3.1 1 1 0 1 1 1 1 Elongator subunit Iki1 COMPASS-Shg1 PF05205.12 EGG22059.1 - 0.055 14.2 0.2 0.12 13.0 0.2 1.6 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 MscL PF01741.18 EGG22061.1 - 0.037 14.3 0.1 0.037 14.3 0.1 1.2 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Nuc_N PF14448.6 EGG22061.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Nuclease N terminal Patched PF02460.18 EGG22062.1 - 7.3e-85 285.7 11.2 2.1e-84 284.2 11.2 1.6 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EGG22062.1 - 1e-47 161.8 29.1 2e-47 160.9 7.5 3.2 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 EGG22062.1 - 3.4e-25 89.0 5.4 6.1e-25 88.2 5.4 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus ACR_tran PF00873.19 EGG22062.1 - 0.001 16.8 11.1 0.0018 16.0 11.1 1.3 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family PH_8 PF15409.6 EGG22064.1 - 5.6e-05 23.3 0.5 0.22 11.8 0.1 4.3 2 1 1 3 3 3 2 Pleckstrin homology domain Ecotin PF03974.13 EGG22064.1 - 0.61 10.1 6.3 0.21 11.6 1.0 3.2 2 0 0 2 2 2 0 Ecotin TERB2 PF15101.6 EGG22065.1 - 1.5e-05 25.2 0.8 1.5e-05 25.2 0.8 3.4 2 1 1 3 3 3 1 Telomere-associated protein TERB2 AAA_24 PF13479.6 EGG22066.1 - 0.0025 17.6 0.2 1.1 9.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 EGG22066.1 - 0.024 14.6 0.5 0.12 12.2 0.5 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 EGG22066.1 - 0.031 14.7 1.5 0.16 12.4 0.6 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGG22066.1 - 0.058 13.7 0.1 0.14 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGG22066.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain SHOCT PF09851.9 EGG22066.1 - 0.13 12.0 3.0 0.23 11.2 3.0 1.4 1 0 0 1 1 1 0 Short C-terminal domain CBM49 PF09478.10 EGG22068.1 - 5.3e-15 55.5 4.5 1.3e-14 54.3 4.5 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 AAA PF00004.29 EGG22069.1 - 1.3e-47 161.5 0.2 2.8e-39 134.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG22069.1 - 1.9e-09 37.2 0.0 3.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain TsaE PF02367.17 EGG22069.1 - 5.1e-05 23.3 0.0 0.11 12.5 0.0 3.0 1 1 2 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EGG22069.1 - 5.2e-05 23.7 1.0 0.0005 20.5 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGG22069.1 - 0.0001 22.3 0.0 0.00042 20.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGG22069.1 - 0.00013 22.1 0.0 0.00063 19.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EGG22069.1 - 0.00026 21.0 8.9 0.0036 17.3 0.0 3.5 4 0 0 4 4 4 2 AAA domain ABC_tran PF00005.27 EGG22069.1 - 0.00099 19.6 0.1 0.0092 16.5 0.0 2.4 2 1 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 EGG22069.1 - 0.0021 18.4 1.0 0.04 14.3 0.0 3.4 3 1 0 3 3 3 1 RNA helicase NACHT PF05729.12 EGG22069.1 - 0.0071 16.3 0.9 1.4 8.8 0.0 2.8 3 0 0 3 3 3 1 NACHT domain DUF815 PF05673.13 EGG22069.1 - 0.0099 15.1 0.0 0.022 13.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 EGG22069.1 - 0.019 14.5 0.1 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 EGG22069.1 - 0.02 15.2 1.6 0.17 12.2 0.1 3.1 3 1 1 4 4 4 0 AAA domain AAA_18 PF13238.6 EGG22069.1 - 0.022 15.3 0.2 0.37 11.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EGG22069.1 - 0.035 13.8 0.0 0.092 12.5 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 EGG22069.1 - 0.1 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Exonuc_VII_S PF02609.16 EGG22072.1 - 0.0041 17.2 0.3 0.0086 16.1 0.3 1.5 1 0 0 1 1 1 1 Exonuclease VII small subunit TACC_C PF05010.14 EGG22073.1 - 0.0077 16.0 27.9 0.016 15.0 27.9 1.4 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SopA PF13981.6 EGG22073.1 - 0.012 16.0 3.5 0.67 10.4 0.1 2.9 3 1 0 3 3 3 0 SopA-like central domain PepSY_TM_like_2 PF16357.5 EGG22073.1 - 0.019 14.9 1.9 0.019 14.9 1.9 2.2 1 1 1 2 2 2 0 Putative PepSY_TM-like Mnd1 PF03962.15 EGG22073.1 - 0.089 13.1 1.3 0.42 11.0 0.9 2.4 2 0 0 2 2 2 0 Mnd1 HTH domain LRAT PF04970.13 EGG22073.1 - 0.32 11.3 6.6 1.7 8.9 0.2 2.9 1 1 2 3 3 3 0 Lecithin retinol acyltransferase SBD_N PF07005.11 EGG22073.1 - 0.72 9.5 2.8 1.4 8.6 2.4 1.6 1 1 0 1 1 1 0 Sugar-binding N-terminal domain HMG_box_5 PF14887.6 EGG22073.1 - 8.9 6.4 11.7 4.8 7.2 2.9 3.2 3 1 0 3 3 3 0 HMG (high mobility group) box 5 Ribosomal_S11 PF00411.19 EGG22074.1 - 2.3e-05 24.8 0.0 3.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S11 PF00411.19 EGG22076.1 - 3.3e-42 143.3 1.5 4.8e-42 142.8 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 IPPT PF01715.17 EGG22077.1 - 2e-56 191.4 2.5 2e-56 191.4 2.5 1.7 2 1 0 2 2 2 1 IPP transferase zf-C2H2_jaz PF12171.8 EGG22077.1 - 8e-07 29.2 2.0 1.9e-06 28.0 2.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG22077.1 - 3e-06 27.4 1.0 7.1e-06 26.2 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Hpr_kinase_C PF07475.12 EGG22077.1 - 0.00029 20.4 0.3 0.00088 18.8 0.3 1.8 1 0 0 1 1 1 1 HPr Serine kinase C-terminal domain IPT PF01745.16 EGG22077.1 - 0.0013 18.2 0.0 0.0036 16.7 0.0 1.8 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 EGG22077.1 - 0.0029 17.8 2.0 0.068 13.3 0.0 3.2 4 0 0 4 4 3 1 AAA domain RsgA_GTPase PF03193.16 EGG22077.1 - 0.03 14.2 0.2 0.03 14.2 0.2 2.3 2 0 0 2 2 2 0 RsgA GTPase IstB_IS21 PF01695.17 EGG22077.1 - 0.04 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Lipocalin_5 PF13924.6 EGG22077.1 - 0.049 13.4 0.4 0.14 11.9 0.4 1.8 1 0 0 1 1 1 0 Lipocalin-like domain RNA_helicase PF00910.22 EGG22077.1 - 0.082 13.3 0.0 0.082 13.3 0.0 3.0 3 1 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 EGG22077.1 - 0.083 13.4 0.0 0.083 13.4 0.0 3.8 3 2 0 3 3 2 0 AAA domain AAA_22 PF13401.6 EGG22077.1 - 0.089 13.1 1.2 0.47 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EGG22077.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dehydrin PF00257.19 EGG22077.1 - 0.43 11.1 14.1 1.7 9.2 0.5 3.4 3 0 0 3 3 3 0 Dehydrin zf-C2H2_3rep PF18868.1 EGG22077.1 - 0.5 11.1 9.2 0.28 11.9 1.9 3.3 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats NOB1_Zn_bind PF08772.11 EGG22077.1 - 1.1 9.4 4.3 2.5 8.4 0.2 2.5 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like UBX PF00789.20 EGG22078.1 - 3.3e-14 52.9 0.2 9e-14 51.4 0.2 1.8 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 EGG22078.1 - 0.0025 17.9 0.0 0.0025 17.9 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin-like ubiquitin PF00240.23 EGG22078.1 - 0.0091 15.7 3.5 0.39 10.5 0.0 3.8 4 0 0 4 4 4 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGG22078.1 - 0.18 12.3 5.2 0.19 12.2 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-like domain Use1 PF09753.9 EGG22078.1 - 0.89 9.2 12.0 0.064 13.0 5.6 1.9 2 0 0 2 2 2 0 Membrane fusion protein Use1 DUF966 PF06136.13 EGG22078.1 - 7.2 6.2 14.1 9 5.9 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Abhydrolase_1 PF00561.20 EGG22079.1 - 5.2e-35 121.3 0.0 8.7e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG22079.1 - 3.5e-11 44.1 0.0 7.7e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG22079.1 - 4.3e-09 36.0 0.0 9.7e-08 31.6 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGG22079.1 - 0.0054 16.2 0.0 0.77 9.2 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family CooC_C PF15976.5 EGG22079.1 - 0.087 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 CS1-pili formation C-terminal DUF1772 PF08592.11 EGG22080.1 - 4.4e-19 69.2 0.2 5.3e-19 68.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) SP24 PF16504.5 EGG22080.1 - 0.0011 19.0 0.1 0.0019 18.2 0.1 1.4 1 0 0 1 1 1 1 Putative virion membrane protein of plant and insect virus YchF-GTPase_C PF06071.13 EGG22081.1 - 2.3e-35 120.6 0.4 7.2e-35 119.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGG22081.1 - 2.6e-22 79.0 0.1 8e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG22081.1 - 3.5e-06 26.6 0.0 7.8e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGG22081.1 - 0.061 13.2 0.3 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 EGG22081.1 - 0.12 11.3 0.0 0.27 10.2 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GlcNAc PF11397.8 EGG22082.1 - 9.8e-85 285.1 0.4 5.6e-72 243.1 0.2 2.0 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) PMBR PF09373.10 EGG22082.1 - 0.0057 16.8 0.2 0.015 15.4 0.2 1.8 1 0 0 1 1 1 1 Pseudomurein-binding repeat Smg8_Smg9 PF10220.9 EGG22083.1 - 5.7e-62 210.3 20.8 7.1e-38 130.5 3.0 4.1 3 1 1 4 4 4 3 Smg8_Smg9 TAF PF02969.17 EGG22084.1 - 3.6e-29 100.7 0.2 7.3e-29 99.8 0.2 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 EGG22084.1 - 1.3e-25 89.5 0.5 3.3e-25 88.2 0.1 1.9 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TFIID-31kDa PF02291.15 EGG22084.1 - 0.0071 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EGG22084.1 - 0.0099 16.1 0.1 0.13 12.5 0.1 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone OS-D PF03392.13 EGG22084.1 - 0.015 15.4 0.2 3 8.0 0.0 3.0 3 0 0 3 3 3 0 Insect pheromone-binding family, A10/OS-D DUF737 PF05300.11 EGG22084.1 - 0.019 15.4 1.2 0.028 14.8 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Histone PF00125.24 EGG22084.1 - 0.055 13.8 4.0 0.093 13.1 0.1 2.5 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Menin PF05053.13 EGG22084.1 - 0.1 10.9 2.3 0.068 11.5 0.6 1.5 2 0 0 2 2 2 0 Menin Perilipin PF03036.16 EGG22084.1 - 0.12 11.4 5.4 0.22 10.5 5.2 1.5 1 1 0 1 1 1 0 Perilipin family SAM_PNT PF02198.16 EGG22085.1 - 6.7e-07 29.2 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 EGG22085.1 - 0.0063 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) BCS1_N PF08740.11 EGG22086.1 - 1.5e-46 158.8 1.0 2.3e-46 158.1 1.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGG22086.1 - 9.9e-17 61.6 0.0 6e-15 55.8 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGG22086.1 - 4e-05 24.1 0.0 6.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 EGG22086.1 - 0.0007 18.8 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EGG22086.1 - 0.0029 18.0 0.0 0.0072 16.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.6 EGG22086.1 - 0.0032 17.3 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGG22086.1 - 0.0071 16.6 0.5 0.36 11.1 0.2 3.0 2 1 0 2 2 2 1 AAA domain PPV_E1_C PF00519.17 EGG22086.1 - 0.016 14.1 0.0 0.035 13.0 0.0 1.5 2 0 0 2 2 2 0 Papillomavirus helicase ABC_tran PF00005.27 EGG22086.1 - 0.017 15.6 0.1 0.052 14.1 0.1 1.9 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EGG22086.1 - 0.021 14.5 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EGG22086.1 - 0.025 14.1 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EGG22086.1 - 0.027 15.0 0.0 0.081 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGG22086.1 - 0.031 14.4 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGG22086.1 - 0.031 13.8 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGG22086.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGG22086.1 - 0.052 12.9 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 EGG22086.1 - 0.053 13.5 0.1 0.19 11.7 0.1 2.1 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGG22086.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EGG22086.1 - 0.12 12.3 0.0 0.95 9.3 0.0 2.2 2 1 1 3 3 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 EGG22086.1 - 0.15 12.1 0.1 0.5 10.5 0.1 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF1244 PF06844.11 EGG22086.1 - 0.22 11.7 1.1 0.78 10.0 0.0 2.3 3 0 0 3 3 2 0 Protein of unknown function (DUF1244) THUMP PF02926.17 EGG22087.1 - 5.6e-08 33.0 1.6 9.3e-08 32.3 1.6 1.5 1 0 0 1 1 1 1 THUMP domain DUF3381 PF11861.8 EGG22087.1 - 0.021 14.7 0.9 0.021 14.7 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) FRB_dom PF08771.11 EGG22087.1 - 0.14 12.6 3.7 0.13 12.7 1.5 2.2 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain HET PF06985.11 EGG22087.1 - 0.17 12.2 1.7 1.6 9.1 0.1 2.4 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) DENN PF02141.21 EGG22088.1 - 1e-27 97.3 5.3 7.5e-24 84.7 0.4 2.6 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 EGG22088.1 - 5.3e-06 27.1 1.1 0.00017 22.3 0.0 2.9 2 0 0 2 2 2 1 uDENN domain NOA36 PF06524.12 EGG22088.1 - 0.3 10.4 10.4 0.5 9.6 10.4 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 EGG22088.1 - 6.8 6.3 17.2 0.011 15.5 5.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein E1_dh PF00676.20 EGG22088.1 - 8.2 5.3 6.2 14 4.5 6.2 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Tim54 PF11711.8 EGG22089.1 - 0.0039 16.0 0.5 0.0052 15.6 0.5 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Shisa PF13908.6 EGG22089.1 - 0.34 11.1 4.6 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator FAM76 PF16046.5 EGG22089.1 - 1.1 8.5 9.2 1.8 7.8 9.2 1.4 1 0 0 1 1 1 0 FAM76 protein Macoilin PF09726.9 EGG22089.1 - 5.1 5.5 11.4 8.4 4.8 11.4 1.4 1 0 0 1 1 1 0 Macoilin family PAP1 PF08601.10 EGG22089.1 - 10 5.8 17.5 0.54 9.9 12.5 1.6 2 0 0 2 2 2 0 Transcription factor PAP1 VASt PF16016.5 EGG22090.1 - 6.8e-12 46.0 0.1 6.8e-12 46.0 0.1 2.1 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain DUF4657 PF15552.6 EGG22090.1 - 0.0044 16.6 0.3 0.0067 16.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4657) Polyketide_cyc PF03364.20 EGG22090.1 - 0.033 14.4 0.0 0.99 9.6 0.0 2.3 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport DUF2505 PF10698.9 EGG22090.1 - 0.033 14.3 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) Spt20 PF12090.8 EGG22090.1 - 0.73 9.4 26.8 0.047 13.3 21.4 1.8 2 0 0 2 2 2 0 Spt20 family HCO3_cotransp PF00955.21 EGG22090.1 - 1.6 7.4 7.1 2.8 6.7 7.1 1.4 1 0 0 1 1 1 0 HCO3- transporter family Presenilin PF01080.17 EGG22090.1 - 6.8 5.3 7.3 9.7 4.8 7.3 1.3 1 0 0 1 1 1 0 Presenilin AIM24 PF01987.17 EGG22091.1 - 8.2e-44 149.8 0.3 9.2e-44 149.7 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Methyltransf_25 PF13649.6 EGG22092.1 - 6.2e-12 46.1 0.0 1.7e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGG22092.1 - 2e-10 40.6 0.8 3.4e-10 39.8 0.2 1.6 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EGG22092.1 - 3.1e-10 40.1 0.0 5.9e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG22092.1 - 1.4e-09 38.5 0.0 4.3e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG22092.1 - 1.4e-07 31.5 0.0 5.6e-07 29.5 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGG22092.1 - 1.5e-07 30.6 0.1 2.2e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EGG22092.1 - 1.3e-05 24.7 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EGG22092.1 - 2.6e-05 23.8 0.1 4.2e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.16 EGG22092.1 - 8.9e-05 22.4 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 EGG22092.1 - 0.00011 22.9 0.0 0.00023 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGG22092.1 - 0.00014 21.9 0.1 0.00025 21.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGG22092.1 - 0.0003 20.6 0.1 0.00059 19.6 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 EGG22092.1 - 0.00061 19.9 0.0 0.0014 18.7 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.19 EGG22092.1 - 0.0019 18.0 0.0 0.0051 16.6 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EGG22092.1 - 0.002 17.5 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 EGG22092.1 - 0.004 16.6 2.1 0.02 14.3 0.2 2.5 1 1 1 2 2 2 1 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 EGG22092.1 - 0.039 13.2 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_24 PF13578.6 EGG22092.1 - 0.15 13.1 0.0 0.33 12.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PseudoU_synth_1 PF01416.20 EGG22093.1 - 1.1e-10 42.0 0.0 3.5e-08 33.9 0.0 3.2 2 1 0 2 2 2 1 tRNA pseudouridine synthase DUF4746 PF15928.5 EGG22093.1 - 0.00043 19.8 8.5 0.00043 19.8 8.5 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4746) Myc_N PF01056.18 EGG22093.1 - 0.0029 17.6 8.4 0.0029 17.6 8.4 2.1 2 0 0 2 2 2 1 Myc amino-terminal region SpoIIIAH PF12685.7 EGG22093.1 - 0.0062 16.4 15.3 0.0062 16.4 15.3 2.6 2 1 0 2 2 2 1 SpoIIIAH-like protein DUF2079 PF09852.9 EGG22093.1 - 1.1 8.0 2.4 33 3.1 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) DUF2201_N PF13203.6 EGG22093.1 - 6.8 6.2 15.4 0.051 13.2 5.9 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain Neur_chan_memb PF02932.16 EGG22093.1 - 7.9 6.5 17.0 2.4 8.2 9.2 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GPCR_chapero_1 PF11904.8 EGG22093.1 - 8 5.8 25.0 4.6 6.6 3.9 2.4 2 0 0 2 2 2 0 GPCR-chaperone TIG PF01833.24 EGG22094.1 - 3.3e-21 75.1 42.2 9.4e-09 35.2 1.6 8.5 9 0 0 9 9 9 3 IPT/TIG domain DNase_II PF03265.15 EGG22094.1 - 1.1e-17 64.3 24.6 2.7e-11 43.3 2.6 5.8 4 1 1 5 5 5 2 Deoxyribonuclease II PRKCSH_1 PF13015.6 EGG22094.1 - 8.1e-06 25.6 5.1 8.4e-05 22.3 0.8 2.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF4611 PF15387.6 EGG22094.1 - 0.058 13.6 0.4 0.19 12.0 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF896 PF05979.12 EGG22094.1 - 0.084 12.8 0.4 0.29 11.1 0.4 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) DUF1642 PF07852.11 EGG22094.1 - 6.2 7.4 11.0 5.6 7.5 1.3 3.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1642) DUF445 PF04286.12 EGG22094.1 - 8.6 6.0 7.2 1.1 9.0 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF445) DNase_II PF03265.15 EGG22095.1 - 6.9e-57 193.2 13.5 6.9e-57 193.2 13.5 2.6 2 0 0 2 2 2 1 Deoxyribonuclease II TIG PF01833.24 EGG22095.1 - 1.9e-53 178.5 85.5 6e-11 42.3 2.7 13.1 12 0 0 12 12 12 10 IPT/TIG domain SdrD_B PF17210.3 EGG22095.1 - 3.3e-06 27.3 1.5 2.3e-05 24.6 0.0 3.2 3 0 0 3 3 3 1 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG22095.1 - 0.018 15.3 0.0 0.06 13.6 0.0 1.9 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain SUIM_assoc PF16619.5 EGG22095.1 - 4.4 7.4 11.8 0.59 10.2 2.7 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Voldacs PF03517.13 EGG22096.1 - 0.00077 19.6 12.9 0.00077 19.6 12.9 2.5 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling DDE_Tnp_1_2 PF13586.6 EGG22096.1 - 0.02 15.3 0.9 0.49 10.8 0.6 2.6 2 0 0 2 2 2 0 Transposase DDE domain CENP-B_dimeris PF09026.10 EGG22096.1 - 1.2 9.5 29.1 0.66 10.4 8.6 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF533 PF04391.12 EGG22096.1 - 1.7 8.2 7.2 9.2 5.8 4.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Androgen_recep PF02166.16 EGG22096.1 - 6.8 5.4 14.2 13 4.5 14.2 1.5 1 0 0 1 1 1 0 Androgen receptor WD40 PF00400.32 EGG22097.1 - 8.9e-09 35.9 21.5 2.3e-06 28.2 1.0 8.0 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG22097.1 - 0.0031 17.8 7.7 0.56 10.6 0.0 5.4 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain VCH_CASS14 PF18315.1 EGG22097.1 - 0.022 14.8 0.0 0.067 13.2 0.0 1.8 1 0 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain Hira PF07569.11 EGG22097.1 - 0.089 12.5 1.4 6 6.5 0.2 3.1 2 0 0 2 2 2 0 TUP1-like enhancer of split BRCA2 PF00634.18 EGG22098.1 - 0.016 14.9 2.9 0.039 13.6 0.2 2.2 2 0 0 2 2 2 0 BRCA2 repeat DUF1363 PF07101.11 EGG22098.1 - 0.09 13.1 0.2 0.16 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) POP1 PF06978.11 EGG22098.1 - 0.43 10.5 8.3 0.52 10.3 8.3 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 CDC45 PF02724.14 EGG22098.1 - 1.3 7.2 17.4 1.6 7.0 17.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Med19 PF10278.9 EGG22098.1 - 1.6 8.7 14.8 0.56 10.1 12.4 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Macoilin PF09726.9 EGG22098.1 - 8 4.9 16.4 9.9 4.6 16.4 1.1 1 0 0 1 1 1 0 Macoilin family Aminotran_1_2 PF00155.21 EGG22099.1 - 1.4e-53 182.4 0.0 1.6e-53 182.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGG22099.1 - 0.0007 19.0 0.0 0.00098 18.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGG22099.1 - 0.0048 15.9 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGG22099.1 - 0.026 13.1 0.0 0.049 12.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 EGG22099.1 - 0.057 12.0 0.0 0.14 10.7 0.0 1.5 1 1 0 1 1 1 0 Serine hydroxymethyltransferase Epimerase PF01370.21 EGG22100.1 - 9.1e-17 61.3 1.5 5e-16 58.9 1.5 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG22100.1 - 1.1e-15 57.4 0.3 1.5e-15 56.9 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGG22100.1 - 2.8e-12 46.3 0.0 4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGG22100.1 - 1.3e-11 44.5 1.4 3.3e-11 43.2 0.8 1.9 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EGG22100.1 - 1.3e-09 38.0 0.0 2.3e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EGG22100.1 - 1.6e-09 37.9 0.0 6.4e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGG22100.1 - 0.00068 18.9 1.4 0.001 18.3 1.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EGG22100.1 - 0.049 13.5 0.0 0.26 11.2 0.0 1.9 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 EGG22100.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Rax2 PF12768.7 EGG22100.1 - 0.16 11.4 4.2 0.62 9.5 0.5 2.7 2 1 0 2 2 2 0 Cortical protein marker for cell polarity Gamma_PGA_hydro PF05908.11 EGG22100.1 - 0.38 10.1 4.0 0.74 9.2 3.5 1.6 2 0 0 2 2 2 0 Poly-gamma-glutamate hydrolase Apis_Csd PF11671.8 EGG22100.1 - 3.9 7.5 9.7 21 5.1 6.4 2.4 2 0 0 2 2 2 0 Complementary sex determiner protein Pkinase PF00069.25 EGG22101.1 - 4.9e-47 160.5 0.5 6.2e-46 156.9 0.5 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG22101.1 - 2.8e-23 82.5 0.0 1.5e-20 73.6 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Ndc1_Nup PF09531.10 EGG22101.1 - 0.12 11.0 9.2 0.22 10.2 9.2 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.8 EGG22101.1 - 0.21 11.1 22.4 0.92 9.1 0.1 2.4 2 0 0 2 2 2 0 Spt20 family NUDE_C PF04880.13 EGG22101.1 - 0.92 10.0 14.7 1.1 9.7 13.0 1.9 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Coilin_N PF15862.5 EGG22101.1 - 1.1 9.1 8.1 0.072 12.9 2.5 1.9 2 0 0 2 2 2 0 Coilin N-terminus PB1 PF00564.24 EGG22102.1 - 5.8e-13 48.6 0.1 1.1e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 PB1 domain RRM_1 PF00076.22 EGG22103.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG22103.1 - 0.01 15.7 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif LMBR1 PF04791.16 EGG22105.1 - 1.1e-59 202.7 31.8 5.7e-34 117.9 8.3 4.1 2 1 2 4 4 4 3 LMBR1-like membrane protein DUF3439 PF11921.8 EGG22105.1 - 0.0051 16.8 7.4 0.012 15.5 7.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) PAP_central PF04928.17 EGG22105.1 - 0.029 13.4 1.0 2.4 7.1 2.9 2.1 1 1 0 2 2 2 0 Poly(A) polymerase central domain Mucin PF01456.17 EGG22105.1 - 2.3 8.2 12.2 5.5 7.0 12.2 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2981 PF11200.8 EGG22105.1 - 9.6 5.8 13.8 0.83 9.3 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2981) Pex14_N PF04695.13 EGG22106.1 - 0.0077 16.9 1.8 0.019 15.6 1.2 1.8 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.10 EGG22106.1 - 0.029 13.1 0.3 0.56 8.8 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup LRRC37AB_C PF14914.6 EGG22106.1 - 0.086 12.7 1.7 0.16 11.8 1.7 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Presenilin PF01080.17 EGG22106.1 - 0.33 9.7 6.7 0.35 9.6 5.9 1.5 1 1 0 1 1 1 0 Presenilin Orf78 PF06024.12 EGG22106.1 - 1.3 9.4 10.5 0.042 14.1 3.5 2.1 2 0 0 2 2 2 0 Orf78 (ac78) EOS1 PF12326.8 EGG22106.1 - 2.3 8.1 8.4 0.2 11.6 3.2 1.8 2 0 0 2 2 2 0 N-glycosylation protein Spt20 PF12090.8 EGG22106.1 - 4.4 6.8 14.2 6.1 6.4 14.2 1.1 1 0 0 1 1 1 0 Spt20 family Pox_D5 PF03288.16 EGG22107.1 - 0.079 13.4 1.3 0.5 10.9 0.2 3.1 2 0 0 2 2 2 0 Poxvirus D5 protein-like DUF473 PF04322.12 EGG22107.1 - 0.3 10.9 2.4 1.2 9.0 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF473) Pkinase_Tyr PF07714.17 EGG22108.1 - 2.5e-64 217.1 0.0 3.4e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG22108.1 - 8.3e-57 192.5 0.0 1.3e-56 191.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGG22108.1 - 0.0029 17.6 0.1 0.0058 16.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family NICE-3 PF07406.11 EGG22108.1 - 0.42 10.6 1.2 0.83 9.6 0.4 1.7 2 0 0 2 2 2 0 NICE-3 protein FtsJ PF01728.19 EGG22109.1 - 1.1e-45 155.9 0.4 1.7e-45 155.3 0.4 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PSII_Pbs31 PF18240.1 EGG22109.1 - 0.031 14.7 1.3 2.8 8.5 0.1 2.8 2 1 0 3 3 3 0 Photosystem II Psb31 protein Glyco_hydro_38N PF01074.22 EGG22110.1 - 5.5e-42 144.1 4.0 5.5e-42 144.1 4.0 3.1 2 1 0 3 3 3 1 Glycosyl hydrolases family 38 N-terminal domain Syntaxin-18_N PF10496.9 EGG22111.1 - 5.5e-19 68.2 3.0 5.5e-19 68.2 3.0 3.3 4 1 0 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus Hen1_Lam_C PF18441.1 EGG22111.1 - 0.045 13.6 4.3 0.063 13.1 0.0 2.7 2 1 1 3 3 3 0 Hen1 La-motif C-terminal domain adh_short PF00106.25 EGG22112.1 - 6.9e-40 136.6 2.3 1.2e-39 135.8 2.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG22112.1 - 1.1e-30 107.0 0.8 2e-30 106.1 0.8 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 EGG22112.1 - 3.5e-23 82.0 0.4 6.7e-23 81.1 0.4 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 EGG22112.1 - 4.7e-20 72.2 1.2 8.8e-20 71.4 1.2 1.4 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.6 EGG22112.1 - 0.00015 22.0 0.2 0.00026 21.3 0.2 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Epimerase PF01370.21 EGG22112.1 - 0.011 15.2 0.3 0.018 14.5 0.3 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DIOX_N PF14226.6 EGG22113.1 - 1.8e-08 35.1 0.0 3.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal CCDC53 PF10152.9 EGG22114.1 - 4.1 7.8 13.2 0.069 13.6 4.7 2.3 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex WD40 PF00400.32 EGG22115.1 - 7.1e-48 159.6 28.0 1.7e-06 28.6 0.0 10.0 9 0 0 9 9 9 9 WD domain, G-beta repeat Utp13 PF08625.11 EGG22115.1 - 2.2e-39 134.6 7.8 2.2e-39 134.6 7.8 2.0 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EGG22115.1 - 3.8e-19 68.8 9.8 0.0011 19.2 0.1 7.0 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGG22116.1 - 1.1e-37 127.3 17.5 1e-06 29.3 0.1 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat PUL PF08324.11 EGG22116.1 - 2.6e-28 99.1 5.0 4e-28 98.4 5.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EGG22116.1 - 1.9e-25 89.3 3.2 6.7e-24 84.3 3.2 2.6 1 1 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BBS2_Mid PF14783.6 EGG22116.1 - 0.0016 18.4 0.0 3.2 7.8 0.0 3.7 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Exo84_C PF16528.5 EGG22116.1 - 0.023 14.5 0.0 0.093 12.5 0.0 2.0 2 0 0 2 2 2 0 Exocyst component 84 C-terminal Complex1_LYR PF05347.15 EGG22117.1 - 7.1e-11 42.0 1.6 1.4e-10 41.1 1.5 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGG22117.1 - 8.9e-08 32.8 0.4 8.9e-08 32.8 0.4 1.8 2 1 0 2 2 2 1 Complex1_LYR-like Lipase_3 PF01764.25 EGG22118.1 - 6.6e-06 26.0 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 EGG22118.1 - 0.017 15.3 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain RVT_1 PF00078.27 EGG22119.1 - 1.3e-28 100.0 0.2 2.9e-28 98.9 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EGG22119.1 - 1.4e-25 89.2 0.0 5.4e-25 87.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EGG22119.1 - 1.6e-18 66.9 0.0 5.9e-18 65.1 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 EGG22119.1 - 2.3e-15 56.4 0.5 5.9e-15 55.1 0.5 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EGG22119.1 - 7.2e-14 52.0 0.0 3.2e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 EGG22119.1 - 8.5e-11 41.6 0.8 2.9e-10 39.9 0.8 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EGG22119.1 - 0.0031 17.7 0.0 0.0076 16.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF3437 PF11919.8 EGG22119.1 - 0.029 14.3 0.7 0.095 12.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) CdiA_C_tRNase PF18664.1 EGG22119.1 - 0.033 14.4 0.4 0.17 12.1 0.0 2.4 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain DUF1758 PF05585.12 EGG22119.1 - 0.046 13.5 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF4335 PF14233.6 EGG22119.1 - 0.071 13.0 1.6 0.12 12.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4335) HGD-D PF06050.13 EGG22119.1 - 0.64 9.7 3.7 78 2.9 0.0 3.6 3 0 0 3 3 3 0 2-hydroxyglutaryl-CoA dehydratase, D-component Phage_integrase PF00589.22 EGG22120.1 - 4.7e-10 39.5 0.0 8.5e-10 38.7 0.0 1.4 1 1 0 1 1 1 1 Phage integrase family RasGAP PF00616.19 EGG22121.1 - 1.5e-34 119.5 5.0 6.1e-24 84.9 0.3 2.8 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EGG22121.1 - 1.7e-19 70.0 0.0 3.6e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain YbjN PF10722.9 EGG22121.1 - 0.18 11.8 0.0 0.57 10.2 0.0 1.8 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator MCM PF00493.23 EGG22122.1 - 1.1e-94 315.7 0.0 2e-94 314.9 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGG22122.1 - 3.5e-31 107.7 0.1 9.4e-31 106.3 0.1 1.8 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGG22122.1 - 8.1e-26 90.3 0.4 2e-25 89.0 0.4 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGG22122.1 - 5.5e-12 46.2 4.2 1.4e-10 41.7 1.0 3.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGG22122.1 - 1.4e-08 34.4 0.1 4.5e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGG22122.1 - 0.0045 16.7 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EGG22122.1 - 0.0065 16.5 0.3 0.06 13.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGG22122.1 - 0.0074 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ALMT PF11744.8 EGG22122.1 - 8.8 5.0 9.2 17 4.1 9.2 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Adaptin_N PF01602.20 EGG22123.1 - 1.1e-85 288.2 12.4 2.1e-85 287.3 12.4 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 EGG22123.1 - 1.8e-50 170.2 1.2 3.3e-49 166.1 0.2 2.9 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EGG22123.1 - 5e-48 162.6 0.4 1.2e-47 161.3 0.4 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 EGG22123.1 - 5e-05 23.4 15.0 0.00041 20.4 0.1 4.0 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.5 EGG22123.1 - 0.0051 16.9 0.0 0.029 14.5 0.0 2.3 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 EGG22123.1 - 0.0051 17.0 0.1 24 5.5 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 EGG22123.1 - 0.0085 16.5 0.0 1.3 9.4 0.0 3.5 2 2 1 3 3 3 1 HEAT repeats DUF1548 PF07579.11 EGG22123.1 - 0.11 12.9 0.0 0.11 12.9 0.0 3.4 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1548) Arm PF00514.23 EGG22123.1 - 0.11 12.6 0.1 60 3.9 0.1 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGG22123.1 - 0.19 12.3 0.0 59 4.3 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat VPS13 PF16908.5 EGG22124.1 - 1.6e-42 145.9 5.9 1.6e-42 145.9 5.9 5.9 6 1 0 6 6 6 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EGG22124.1 - 2.4e-42 144.7 0.2 2.4e-42 144.7 0.2 3.9 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EGG22124.1 - 1.1e-31 110.2 33.6 3.4e-25 89.0 9.9 5.4 4 2 1 5 5 5 3 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 EGG22124.1 - 2.6e-21 75.9 0.2 2.8e-20 72.6 0.2 3.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 EGG22124.1 - 2.4e-12 46.8 32.6 6.3e-12 45.4 0.0 6.6 8 0 0 8 8 8 3 Repeating coiled region of VPS13 ATG_C PF09333.11 EGG22124.1 - 1.5e-06 28.5 0.0 6.1e-06 26.5 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain bPH_1 PF08000.11 EGG22124.1 - 0.004 17.2 0.7 0.017 15.2 0.7 2.1 1 0 0 1 1 1 1 Bacterial PH domain DUF3439 PF11921.8 EGG22124.1 - 6.6 6.7 22.4 0.77 9.7 2.2 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3439) PDEase_I PF00233.19 EGG22125.1 - 2.4e-74 250.1 6.0 2.4e-74 250.1 6.0 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Sec20 PF03908.13 EGG22125.1 - 0.096 12.6 0.8 0.39 10.7 0.1 2.4 3 0 0 3 3 3 0 Sec20 DUF4834 PF16118.5 EGG22125.1 - 8.3 7.5 7.8 19 6.3 7.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ABC2_membrane PF01061.24 EGG22126.1 - 6.1e-75 251.2 51.7 2.7e-41 141.3 17.5 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGG22126.1 - 3.3e-44 150.7 0.5 3.1e-23 82.8 0.0 3.1 3 0 0 3 3 3 2 ABC transporter AAA_29 PF13555.6 EGG22126.1 - 4.3e-07 29.6 0.5 0.0024 17.6 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG22126.1 - 4.9e-07 29.8 1.1 0.00026 20.9 0.3 3.5 3 0 0 3 3 3 1 RsgA GTPase AAA_18 PF13238.6 EGG22126.1 - 7.3e-07 29.8 0.2 0.02 15.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EGG22126.1 - 5.3e-06 26.9 0.0 0.066 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EGG22126.1 - 7e-06 25.8 0.0 0.093 12.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EGG22126.1 - 9.5e-05 22.3 3.3 0.33 10.7 0.1 4.2 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EGG22126.1 - 0.00018 21.7 0.1 0.34 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EGG22126.1 - 0.00023 20.7 1.9 0.24 10.8 0.2 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EGG22126.1 - 0.00024 21.4 0.9 0.64 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGG22126.1 - 0.00026 21.3 0.2 0.87 9.9 0.1 3.0 2 1 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 EGG22126.1 - 0.00047 19.8 0.9 0.0086 15.8 0.1 2.6 2 0 0 2 2 2 1 Plant PDR ABC transporter associated PDR_CDR PF06422.12 EGG22126.1 - 0.0005 19.9 1.4 1.2 9.1 0.3 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_2 PF12679.7 EGG22126.1 - 0.0014 18.0 6.6 0.0014 18.0 6.6 2.5 2 0 0 2 2 2 1 ABC-2 family transporter protein Zeta_toxin PF06414.12 EGG22126.1 - 0.008 15.5 0.3 1.7 7.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 EGG22126.1 - 0.011 15.7 1.3 1.3 9.2 0.5 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 EGG22126.1 - 0.037 14.5 0.2 0.037 14.5 0.2 3.9 2 2 1 3 3 3 0 AAA domain Rad17 PF03215.15 EGG22126.1 - 0.041 13.8 1.5 1.2 9.0 0.0 3.3 3 0 0 3 3 3 0 Rad17 P-loop domain RNA_helicase PF00910.22 EGG22126.1 - 0.042 14.2 0.0 19 5.7 0.0 3.0 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 EGG22126.1 - 0.063 13.2 0.3 8 6.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DUF2299 PF10061.9 EGG22126.1 - 0.066 13.0 0.0 0.23 11.2 0.0 1.9 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2299) FtsK_SpoIIIE PF01580.18 EGG22126.1 - 0.11 11.8 0.1 6.9 5.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 EGG22126.1 - 0.2 12.1 0.6 49 4.4 0.0 4.2 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Rap_GAP PF02145.15 EGG22127.1 - 3.9e-49 166.7 1.7 8.1e-49 165.7 0.1 2.4 2 0 0 2 2 2 1 Rap/ran-GAP PLDc_2 PF13091.6 EGG22127.1 - 1.6e-34 118.6 0.1 2.7e-18 66.1 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc_3 PF13918.6 EGG22127.1 - 1.3e-30 106.4 0.4 1.8e-28 99.4 0.5 2.7 2 0 0 2 2 2 1 PLD-like domain PLDc PF00614.22 EGG22127.1 - 5.9e-11 42.1 0.7 6.3e-07 29.3 0.3 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif ANAPC4_WD40 PF12894.7 EGG22127.1 - 0.0052 17.1 0.1 3.6 7.9 0.0 3.4 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 EGG22127.1 - 0.061 13.3 0.0 22 5.2 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Ribosomal_S2 PF00318.20 EGG22128.1 - 3.7e-22 78.6 1.0 1.9e-11 43.6 0.2 2.3 2 1 1 3 3 3 2 Ribosomal protein S2 zf-CCHC_6 PF15288.6 EGG22129.1 - 5.3e-05 23.0 0.8 0.00013 21.7 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle C2 PF00168.30 EGG22130.1 - 1.1e-07 32.1 0.0 2.4e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 C2 domain CHCH PF06747.13 EGG22131.1 - 0.0036 17.4 2.6 0.15 12.3 0.3 2.2 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 EGG22131.1 - 0.011 15.7 2.3 0.14 12.2 0.3 2.1 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 EGG22131.1 - 0.18 12.1 1.7 5.3 7.4 1.8 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Peptidase_M16_C PF05193.21 EGG22132.1 - 9.5e-22 77.9 0.3 5.6e-21 75.4 0.1 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGG22132.1 - 4.3e-16 59.2 0.7 1.6e-15 57.3 0.0 2.2 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) LRR_5 PF13306.6 EGG22132.1 - 0.0039 17.1 0.8 0.013 15.5 0.9 1.8 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) zf-RING_5 PF14634.6 EGG22133.1 - 1.6e-07 31.2 17.8 1.6e-07 31.2 17.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGG22133.1 - 0.0056 17.0 17.6 0.01 16.2 17.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG22133.1 - 0.21 11.4 17.5 0.55 10.1 17.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) XhlA PF10779.9 EGG22133.1 - 0.38 11.0 2.2 0.75 10.0 2.2 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Jnk-SapK_ap_N PF09744.9 EGG22133.1 - 1.3 9.2 11.7 0.088 13.0 3.5 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 zf-C3HC4 PF00097.25 EGG22133.1 - 1.9 8.4 18.3 4.5 7.2 18.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG22133.1 - 6.4 6.9 13.9 19 5.4 13.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Ras PF00071.22 EGG22134.1 - 7.3e-35 120.0 0.8 4.5e-33 114.1 0.2 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 EGG22134.1 - 4.6e-16 59.1 0.1 1.2e-13 51.4 0.0 2.4 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG22134.1 - 3.4e-05 23.4 0.1 5.5e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family RhoGEF PF00621.20 EGG22135.1 - 1.6e-46 158.9 2.2 1.6e-46 158.9 2.2 4.6 3 2 0 3 3 2 1 RhoGEF domain DNA_pol_B_palm PF14792.6 EGG22135.1 - 3e-28 98.3 0.1 9.7e-28 96.7 0.1 2.0 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 EGG22135.1 - 3.2e-14 53.1 0.7 9.3e-14 51.6 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EGG22135.1 - 3e-08 33.3 0.1 7.4e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Mucin PF01456.17 EGG22135.1 - 8.2e-05 22.6 15.0 8.2e-05 22.6 15.0 3.8 4 0 0 4 4 3 2 Mucin-like glycoprotein CDC45 PF02724.14 EGG22135.1 - 0.00016 20.1 47.0 0.0064 14.8 16.3 3.4 3 0 0 3 3 3 3 CDC45-like protein IQ PF00612.27 EGG22135.1 - 0.0003 20.3 1.3 0.0003 20.3 1.3 1.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif SDA1 PF05285.12 EGG22135.1 - 0.00055 19.5 47.9 0.12 11.8 14.9 3.5 3 0 0 3 3 3 3 SDA1 NTP_transf_2 PF01909.23 EGG22135.1 - 0.013 15.8 0.0 0.013 15.8 0.0 3.2 4 0 0 4 4 3 0 Nucleotidyltransferase domain PH PF00169.29 EGG22135.1 - 0.056 14.0 7.6 0.046 14.2 0.7 3.9 2 1 0 2 2 2 0 PH domain ATPgrasp_Ter PF15632.6 EGG22135.1 - 0.07 12.9 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Cwf_Cwc_15 PF04889.12 EGG22135.1 - 1.2 8.9 61.6 0.071 12.8 12.1 3.9 3 0 0 3 3 2 0 Cwf15/Cwc15 cell cycle control protein RCC1 PF00415.18 EGG22137.1 - 3.9e-71 235.5 18.0 2.9e-15 56.6 0.1 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG22137.1 - 2.1e-42 142.1 26.2 1.6e-08 34.1 0.3 7.9 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RasGAP PF00616.19 EGG22137.1 - 3.2e-35 121.7 13.5 1.3e-21 77.3 0.0 4.2 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase RhoGEF PF00621.20 EGG22137.1 - 3.7e-21 76.2 6.1 3.7e-21 76.2 6.1 2.9 1 1 0 2 2 2 1 RhoGEF domain HEAT PF02985.22 EGG22138.1 - 1e-05 25.3 0.0 0.17 12.2 0.1 2.7 2 1 1 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 EGG22138.1 - 0.0003 21.1 0.0 0.00035 20.9 0.0 1.0 1 0 0 1 1 1 1 HEAT repeats DUF3437 PF11919.8 EGG22138.1 - 0.04 13.8 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Cnd1 PF12717.7 EGG22138.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 EGG22139.1 - 0.02 14.0 1.9 0.94 8.5 0.1 2.2 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) GNT-I PF03071.15 EGG22140.1 - 1.2e-24 86.9 6.9 2.8e-14 52.7 1.3 2.3 2 0 0 2 2 2 2 GNT-I family EAP30 PF04157.16 EGG22141.1 - 2.1e-41 141.8 0.2 2.1e-41 141.8 0.2 1.8 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EGG22141.1 - 7.8e-10 38.8 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 RPW8 PF05659.11 EGG22141.1 - 0.025 14.3 0.1 0.064 12.9 0.1 1.7 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SMC_hinge PF06470.13 EGG22141.1 - 0.089 13.1 0.1 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain SPT16 PF08644.11 EGG22141.1 - 0.1 12.8 6.9 3.4 7.8 0.0 2.8 2 1 1 3 3 3 0 FACT complex subunit (SPT16/CDC68) DUF2489 PF10675.9 EGG22141.1 - 0.12 12.3 5.8 0.26 11.2 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Fib_alpha PF08702.10 EGG22141.1 - 0.38 10.9 11.9 1.6 8.9 11.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CHDCT2 PF08074.11 EGG22141.1 - 0.71 10.0 4.0 1.3 9.2 4.0 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Androgen_recep PF02166.16 EGG22141.1 - 7.8 5.2 6.6 12 4.6 6.6 1.2 1 0 0 1 1 1 0 Androgen receptor LIM PF00412.22 EGG22142.1 - 3.4e-30 104.0 41.2 2.9e-12 46.6 7.1 3.4 3 0 0 3 3 3 3 LIM domain Zn-ribbon_8 PF09723.10 EGG22142.1 - 0.04 14.0 1.5 0.04 14.0 1.5 5.8 3 2 3 6 6 6 0 Zinc ribbon domain zf-CHY PF05495.12 EGG22142.1 - 0.06 13.9 43.9 0.32 11.5 16.8 4.3 2 1 2 4 4 4 0 CHY zinc finger Zn_ribbon_SprT PF17283.2 EGG22142.1 - 0.11 12.4 0.1 0.11 12.4 0.1 6.3 4 3 1 5 5 5 0 SprT-like zinc ribbon domain WD40 PF00400.32 EGG22143.1 - 2.4e-63 208.5 17.2 6.2e-10 39.5 0.7 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EGG22143.1 - 1.1e-26 92.9 10.1 1.1e-26 92.9 10.1 2.3 2 0 0 2 2 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EGG22143.1 - 1.5e-23 82.9 0.1 0.0003 21.0 0.0 6.5 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG22143.1 - 7.8e-11 41.5 0.3 0.23 10.4 0.0 5.8 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGG22143.1 - 9.4e-08 31.7 0.0 0.027 13.8 0.0 4.7 5 0 0 5 5 5 1 WD40-like domain eIF2A PF08662.11 EGG22143.1 - 3.4e-07 30.3 0.0 0.018 14.9 0.0 3.8 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EGG22143.1 - 8.7e-07 28.7 0.3 2.2 8.3 0.0 5.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EGG22143.1 - 3.1e-06 26.0 1.9 0.00048 18.8 0.1 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nbas_N PF15492.6 EGG22143.1 - 7.1e-05 22.3 0.2 0.3 10.4 0.0 3.6 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 EGG22143.1 - 0.021 13.2 0.0 9.6 4.4 0.0 3.4 2 2 2 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz SOG2 PF10428.9 EGG22143.1 - 0.49 9.5 14.0 0.64 9.2 14.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Suf PF05843.14 EGG22143.1 - 2.7 7.9 19.8 4.4 7.2 19.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 EGG22143.1 - 5.7 6.9 12.6 9.4 6.2 12.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.16 EGG22143.1 - 7.4 5.3 14.0 10 4.9 14.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SHE3 PF17078.5 EGG22143.1 - 7.8 6.1 21.9 0.07 12.8 5.3 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Ndc1_Nup PF09531.10 EGG22143.1 - 8 5.0 11.6 11 4.5 11.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 EGG22143.1 - 8 4.6 26.0 11 4.1 26.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CENP-H PF05837.12 EGG22143.1 - 8.4 6.9 16.9 0.14 12.6 1.3 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF5122 PF17164.4 EGG22143.1 - 9.1 6.7 7.4 16 5.8 0.0 4.6 6 0 0 6 6 5 0 Domain of unknown function (DUF5122) beta-propeller Response_reg PF00072.24 EGG22144.1 - 1.1e-28 99.6 0.1 2e-20 73.0 0.1 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 EGG22144.1 - 4.4e-17 62.6 0.0 1.1e-16 61.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Y_phosphatase PF00102.27 EGG22146.1 - 3.3e-71 239.6 0.2 3.3e-71 239.6 0.2 4.2 4 0 0 4 4 4 1 Protein-tyrosine phosphatase F-box-like PF12937.7 EGG22146.1 - 6.9e-11 41.9 0.1 1.5e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG22146.1 - 3.8e-08 33.0 0.0 8.2e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Tmemb_185A PF10269.9 EGG22146.1 - 4.4e-05 23.3 23.8 0.013 15.2 6.1 3.0 2 2 0 2 2 2 2 Transmembrane Fragile-X-F protein DSPc PF00782.20 EGG22146.1 - 0.00025 20.9 0.0 0.00025 20.9 0.0 5.8 8 1 1 9 9 9 1 Dual specificity phosphatase, catalytic domain SARAF PF06682.12 EGG22146.1 - 0.02 14.5 0.4 0.02 14.5 0.4 7.6 8 1 1 9 9 9 0 SOCE-associated regulatory factor of calcium homoeostasis YwiC PF14256.6 EGG22146.1 - 2.5 8.4 4.3 17 5.7 0.6 2.4 2 0 0 2 2 2 0 YwiC-like protein DEAD PF00270.29 EGG22147.1 - 1.3e-39 135.8 0.1 2.1e-39 135.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG22147.1 - 1.3e-29 102.8 0.7 3.8e-26 91.6 0.2 2.8 2 1 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGG22147.1 - 3e-07 30.6 0.0 5.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGG22147.1 - 0.00042 19.7 0.0 0.00075 18.9 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ATP-synt_F PF01990.17 EGG22148.1 - 0.009 16.3 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 2 ATP synthase (F/14-kDa) subunit SDA1 PF05285.12 EGG22148.1 - 1.6 8.1 19.8 2.3 7.5 19.8 1.2 1 0 0 1 1 1 0 SDA1 SH3_2 PF07653.17 EGG22149.1 - 3.3e-17 61.9 0.3 1.9e-08 33.9 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EGG22149.1 - 2.6e-16 59.0 0.1 2.2e-09 36.8 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EGG22149.1 - 5.4e-16 58.2 0.0 5.4e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain DUF5641 PF18701.1 EGG22149.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5641) MSA-2c PF12238.8 EGG22150.1 - 0.2 11.7 1.9 0.26 11.2 1.4 1.3 1 1 0 1 1 1 0 Merozoite surface antigen 2c Macoilin PF09726.9 EGG22152.1 - 0.31 9.6 29.4 0.36 9.3 29.4 1.0 1 0 0 1 1 1 0 Macoilin family DUF572 PF04502.13 EGG22152.1 - 0.53 9.9 23.8 0.65 9.6 23.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nop14 PF04147.12 EGG22152.1 - 5 5.2 26.2 6.2 4.9 26.2 1.2 1 0 0 1 1 1 0 Nop14-like family RRM_1 PF00076.22 EGG22153.1 - 1e-31 108.5 0.3 1.4e-15 56.8 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG22153.1 - 2.1e-08 33.9 0.0 3.1e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif TFIIA PF03153.13 EGG22153.1 - 0.00055 20.0 60.8 0.00055 20.0 60.8 4.3 3 1 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit Phage_antitermQ PF06530.12 EGG22153.1 - 0.019 14.9 4.0 0.05 13.5 4.0 1.7 1 0 0 1 1 1 0 Phage antitermination protein Q RRM_7 PF16367.5 EGG22153.1 - 0.046 13.8 5.3 0.37 10.9 0.0 3.9 3 1 0 3 3 3 0 RNA recognition motif Tau95 PF09734.9 EGG22154.1 - 4.1e-37 128.1 2.3 4.1e-37 128.1 2.3 2.7 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EGG22154.1 - 9.9e-20 71.0 0.0 9.9e-20 71.0 0.0 3.4 3 0 0 3 3 3 1 Tau95 Triple barrel domain FAM60A PF15396.6 EGG22154.1 - 1.9 8.5 14.1 6.9 6.6 5.8 2.6 2 0 0 2 2 2 0 Protein Family FAM60A NPR3 PF03666.13 EGG22154.1 - 3.8 6.2 24.7 2.2 7.0 11.1 2.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 EGG22154.1 - 7 5.6 17.0 1.9 7.4 6.8 2.3 2 0 0 2 2 2 0 Solute carrier family 12 Allantoicase PF03561.15 EGG22156.1 - 3.1e-94 312.6 0.0 7.9e-49 165.3 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat HATPase_c PF02518.26 EGG22157.1 - 1.3e-33 115.8 0.2 3.5e-33 114.4 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG22157.1 - 6.7e-19 67.7 0.0 1.7e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EGG22157.1 - 1.1e-10 41.6 0.0 4.9e-10 39.6 0.0 2.2 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EGG22157.1 - 3.3e-05 24.1 0.0 0.00011 22.4 0.0 1.9 2 0 0 2 2 1 1 PAS fold HATPase_c_5 PF14501.6 EGG22157.1 - 0.00014 21.7 0.0 0.00066 19.5 0.0 2.2 1 0 0 1 1 1 1 GHKL domain PAS_8 PF13188.7 EGG22157.1 - 0.00088 19.2 0.0 0.0057 16.6 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EGG22157.1 - 0.012 15.6 0.0 2.1 8.4 0.0 3.6 3 0 0 3 3 3 0 PAS fold HATPase_c_3 PF13589.6 EGG22157.1 - 0.018 14.9 0.0 0.054 13.3 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EGG22157.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain TFIIA PF03153.13 EGG22157.1 - 0.28 11.2 24.5 0.55 10.2 24.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NSP2-B_epitope PF14757.6 EGG22157.1 - 3.9 7.1 10.2 11 5.6 10.2 1.7 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Response_reg PF00072.24 EGG22158.1 - 1.4e-20 73.5 0.6 2.2e-20 72.9 0.6 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Menin PF05053.13 EGG22158.1 - 0.0016 16.9 8.8 0.0016 16.9 8.8 2.1 2 0 0 2 2 2 2 Menin FSA_C PF10479.9 EGG22158.1 - 0.17 10.0 13.0 0.25 9.4 13.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Utp14 PF04615.13 EGG22158.1 - 0.58 8.7 10.2 0.86 8.1 10.2 1.1 1 0 0 1 1 1 0 Utp14 protein PDDEXK_6 PF04720.12 EGG22158.1 - 3.3 7.6 10.7 0.16 11.9 1.6 2.1 2 0 0 2 2 2 0 PDDEXK-like family of unknown function Dicty_REP PF05086.12 EGG22158.1 - 3.3 5.6 22.1 0.0041 15.2 9.1 2.2 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein EGF PF00008.27 EGG22159.1 - 0.3 11.4 7.7 0.63 10.4 7.7 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_alliinase PF04863.13 EGG22159.1 - 1.9 8.9 4.7 4 7.9 4.7 1.5 1 0 0 1 1 1 0 Alliinase EGF-like domain EGF_Tenascin PF18720.1 EGG22159.1 - 2.5 8.2 7.2 5.4 7.2 7.2 1.6 1 0 0 1 1 1 0 Tenascin EGF domain EGF_2 PF07974.13 EGG22159.1 - 9.3 6.7 15.9 0.56 10.6 10.5 1.8 2 0 0 2 2 2 0 EGF-like domain CH PF00307.31 EGG22160.1 - 1.6e-50 169.9 0.9 2.1e-25 89.0 0.0 3.9 3 0 0 3 3 3 2 Calponin homology (CH) domain Spectrin PF00435.21 EGG22160.1 - 2.4e-31 108.3 33.5 1.1e-10 42.0 1.8 4.6 4 0 0 4 4 4 4 Spectrin repeat EF-hand_7 PF13499.6 EGG22160.1 - 7.2e-14 52.0 2.4 3.7e-13 49.7 0.2 3.3 4 0 0 4 4 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EGG22160.1 - 8e-13 47.2 1.2 0.00017 21.3 0.2 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 EGG22160.1 - 2e-12 45.7 0.7 0.00011 21.5 0.0 3.8 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.8 EGG22160.1 - 2.6e-10 40.0 0.0 2.2e-08 33.8 0.0 2.9 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_8 PF13833.6 EGG22160.1 - 1.3e-09 37.7 1.5 1.7e-07 30.9 0.1 2.9 1 1 1 2 2 2 2 EF-hand domain pair EFhand_Ca_insen PF08726.10 EGG22160.1 - 7.3e-08 32.4 0.2 3.1e-07 30.4 0.0 2.3 2 0 0 2 2 1 1 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 EGG22160.1 - 4e-05 22.9 4.1 0.18 11.4 0.0 3.4 3 0 0 3 3 3 2 EF hand DUF4525 PF15027.6 EGG22160.1 - 0.11 12.2 5.4 2.5 7.8 0.2 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4525) EF-hand_4 PF12763.7 EGG22160.1 - 0.26 11.3 3.9 0.79 9.7 0.3 3.6 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand CLU PF13236.6 EGG22160.1 - 0.31 10.8 4.5 1.2 8.9 1.0 2.6 2 0 0 2 2 2 0 Clustered mitochondria NYD-SP28_assoc PF14775.6 EGG22160.1 - 5.5 7.2 18.6 14 5.9 0.5 5.8 5 1 0 5 5 5 0 Sperm tail C-terminal domain VWC PF00093.18 EGG22162.1 - 1.6 9.1 58.5 0.26 11.6 10.7 4.1 3 1 0 3 3 3 0 von Willebrand factor type C domain VWC PF00093.18 EGG22163.1 - 0.33 11.3 59.0 0.29 11.5 10.8 4.1 3 1 1 4 4 4 0 von Willebrand factor type C domain TIG PF01833.24 EGG22164.1 - 1.1e-11 44.6 71.9 1.1e-06 28.7 8.8 8.9 7 2 1 8 8 8 5 IPT/TIG domain Lectin_C PF00059.21 EGG22164.1 - 0.0049 17.6 0.7 0.018 15.8 0.7 2.0 1 0 0 1 1 1 1 Lectin C-type domain EGF_2 PF07974.13 EGG22164.1 - 0.15 12.5 12.6 0.38 11.2 12.6 1.8 1 0 0 1 1 1 0 EGF-like domain BB_PF PF18063.1 EGG22165.1 - 2.5e-27 95.8 2.5 8.8e-27 94.0 2.5 1.7 1 1 0 1 1 1 1 Beta barrel Pore-forming domain Ank_2 PF12796.7 EGG22166.1 - 4.6e-48 161.7 14.9 1.1e-11 45.2 0.1 7.2 2 1 6 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22166.1 - 2.6e-41 139.5 16.3 3.1e-06 27.6 0.1 10.9 8 4 6 14 14 14 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22166.1 - 4.9e-36 122.3 17.9 0.002 18.4 0.0 13.9 3 1 11 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22166.1 - 5.5e-27 90.9 8.0 0.63 10.8 0.0 14.5 14 2 2 16 16 16 6 Ankyrin repeat Ank PF00023.30 EGG22166.1 - 6.8e-16 57.9 6.1 1.8 9.1 0.0 12.1 7 4 7 14 14 14 5 Ankyrin repeat DUF5049 PF16468.5 EGG22166.1 - 1e-13 50.9 22.0 1.1 9.2 0.0 12.2 8 4 6 14 14 14 5 Domain of unknown function (DUF5049) FBD PF08387.10 EGG22166.1 - 0.046 13.6 4.1 2 8.4 0.1 4.5 5 1 0 5 5 5 0 FBD DUF5099 PF17025.5 EGG22166.1 - 0.055 13.9 4.5 81 3.7 0.0 5.1 2 1 1 5 5 5 0 Domain of unknown function (DUF5099) Ank_2 PF12796.7 EGG22167.1 - 8.1e-15 55.2 10.5 1.1e-06 29.2 0.6 6.7 4 3 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22167.1 - 3.5e-12 46.6 8.4 0.01 16.4 0.0 9.0 9 3 2 11 11 11 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 EGG22167.1 - 3.4e-07 30.1 11.2 0.073 13.0 0.1 5.8 3 1 3 6 6 6 2 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EGG22167.1 - 1.1e-06 28.4 3.4 8.2 7.4 0.0 8.6 9 1 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 EGG22167.1 - 0.0029 17.9 0.7 98 3.4 0.0 6.5 5 2 3 8 8 8 0 Ankyrin repeats (many copies) GIDA_assoc PF13932.6 EGG22167.1 - 0.21 11.8 2.4 0.52 10.5 2.4 1.6 1 0 0 1 1 1 0 GidA associated domain AAA-ATPase_like PF09820.9 EGG22168.1 - 1.7e-06 27.7 0.1 2.3e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Predicted AAA-ATPase NLPC_P60 PF00877.19 EGG22169.1 - 2.2e-10 40.5 0.3 5.9e-05 23.0 0.9 2.3 2 0 0 2 2 2 2 NlpC/P60 family BTB_2 PF02214.22 EGG22170.1 - 1.6e-17 63.6 1.1 3.2e-17 62.7 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_1 PF01344.25 EGG22170.1 - 3.2e-07 29.8 6.5 1.3 8.6 0.1 5.4 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EGG22170.1 - 0.00011 22.3 7.0 0.62 10.4 0.1 4.5 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EGG22170.1 - 0.089 12.8 5.9 20 5.4 0.0 4.8 5 0 0 5 5 5 0 Kelch motif Kelch_4 PF13418.6 EGG22170.1 - 0.8 9.8 4.6 24 5.0 0.0 4.5 4 0 0 4 4 4 0 Galactose oxidase, central domain Aquarius_N PF16399.5 EGG22171.1 - 4.4e-169 564.1 17.9 4.8e-159 531.0 14.2 3.2 2 1 0 2 2 2 2 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 EGG22171.1 - 1.2e-29 104.0 0.0 1.2e-29 104.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 EGG22171.1 - 1.7e-26 93.1 3.0 6.4e-26 91.2 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGG22171.1 - 3e-08 34.1 0.0 2.9e-07 30.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG22171.1 - 7.2e-08 32.4 0.0 0.00033 20.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EGG22171.1 - 9.5e-06 25.7 6.9 1.4e-05 25.2 0.1 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 EGG22171.1 - 1.9e-05 24.4 0.1 4.3e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EGG22171.1 - 5.4e-05 23.1 0.0 0.06 13.1 0.0 3.5 2 1 1 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 EGG22171.1 - 0.00021 21.1 0.1 0.0023 17.7 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EGG22171.1 - 0.0019 17.5 4.7 0.0067 15.7 0.0 3.2 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EGG22171.1 - 0.0062 16.9 0.0 1 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EGG22171.1 - 0.026 15.0 0.0 0.1 13.0 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EGG22171.1 - 0.049 13.0 0.0 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 EGG22171.1 - 0.11 12.4 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 NACHT domain ATP-synt_D PF01813.17 EGG22173.1 - 7.9e-66 221.6 3.5 1.1e-65 221.1 3.5 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Ank_2 PF12796.7 EGG22174.1 - 7.3e-53 177.1 17.1 5.4e-11 42.9 0.0 7.6 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22174.1 - 3.2e-35 120.1 11.8 3.3e-05 24.4 0.0 9.4 5 2 7 13 13 13 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22174.1 - 1.4e-34 117.7 10.4 0.0017 18.6 0.0 12.8 2 1 11 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22174.1 - 3.9e-29 97.4 3.9 0.061 13.9 0.0 14.6 15 1 1 16 16 16 6 Ankyrin repeat Ank PF00023.30 EGG22174.1 - 1.6e-16 59.9 0.2 2.9 8.5 0.0 12.5 10 2 4 15 15 15 3 Ankyrin repeat DUF5049 PF16468.5 EGG22174.1 - 1.1e-07 31.6 6.6 5.8 6.9 0.1 9.1 7 1 3 10 10 10 2 Domain of unknown function (DUF5049) Ank_2 PF12796.7 EGG22175.1 - 5.8e-15 55.7 0.1 1.4e-07 32.0 0.0 2.8 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22175.1 - 5.4e-08 32.9 0.0 0.019 15.3 0.0 4.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22175.1 - 1e-06 29.2 0.1 0.03 14.9 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22175.1 - 9.7e-06 25.6 0.9 9.7 7.1 0.0 5.7 7 0 0 7 7 7 2 Ankyrin repeat DUF5049 PF16468.5 EGG22175.1 - 0.012 15.5 0.4 11 5.9 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22175.1 - 0.17 12.4 0.2 54 4.5 0.0 3.8 3 2 1 4 4 4 0 Ankyrin repeat Arm PF00514.23 EGG22176.1 - 5.7e-67 219.9 20.4 3.9e-11 42.6 0.1 9.2 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGG22176.1 - 4.1e-18 65.5 3.3 4.3e-05 23.9 0.0 5.8 6 0 0 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 EGG22176.1 - 1.6e-17 62.8 2.6 3.8e-17 61.6 2.6 1.7 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 EGG22176.1 - 2.4e-14 53.5 3.2 4.1e-14 52.8 1.4 2.3 2 0 0 2 2 2 1 Importin beta binding domain HEAT_2 PF13646.6 EGG22176.1 - 1.6e-11 44.4 0.3 0.031 14.7 0.0 5.4 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.22 EGG22176.1 - 1.2e-08 34.4 0.7 0.078 13.3 0.0 7.4 8 0 0 8 8 8 1 HEAT repeat Atx10homo_assoc PF09759.9 EGG22176.1 - 0.011 15.8 0.1 1.3 9.1 0.0 3.1 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain TNV_CP PF03898.13 EGG22176.1 - 0.012 14.9 1.1 0.11 11.8 0.1 2.4 2 0 0 2 2 2 0 Satellite tobacco necrosis virus coat protein Proteasom_PSMB PF10508.9 EGG22176.1 - 0.023 13.3 0.0 0.17 10.3 0.0 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit CTNNBL PF08216.11 EGG22176.1 - 0.054 13.7 0.0 11 6.2 0.0 2.9 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear Ank_2 PF12796.7 EGG22177.1 - 0.00081 19.9 0.1 1.2 9.8 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG22177.1 - 0.0044 17.4 0.2 12 6.9 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat DUF3447 PF11929.8 EGG22177.1 - 0.011 15.7 7.9 1.3 9.0 0.0 4.7 3 1 2 5 5 5 0 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EGG22177.1 - 0.012 16.2 1.0 7.1 7.3 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeats (many copies) tRNA_synt_1c_R1 PF04558.15 EGG22177.1 - 0.075 13.0 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DnaB_2 PF07261.11 EGG22177.1 - 0.35 10.6 2.1 2.2 8.1 0.2 3.1 3 0 0 3 3 3 0 Replication initiation and membrane attachment TIG PF01833.24 EGG22178.1 - 6.7e-18 64.5 17.0 7.8e-08 32.3 4.1 4.4 3 0 0 3 3 3 3 IPT/TIG domain Ank_2 PF12796.7 EGG22179.1 - 6.5e-41 138.8 12.5 1.4e-09 38.4 0.0 7.3 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22179.1 - 1.1e-33 115.1 7.9 3e-06 27.7 0.0 9.3 7 2 2 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22179.1 - 3.4e-24 84.6 13.4 0.25 11.7 0.0 11.9 3 2 9 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22179.1 - 4e-20 69.8 0.9 5 8.0 0.0 12.8 13 0 0 13 13 13 3 Ankyrin repeat DUF5049 PF16468.5 EGG22179.1 - 2.6e-11 43.2 11.0 2.2 8.2 0.0 10.3 6 3 5 11 11 11 3 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22179.1 - 1.4e-09 38.0 0.4 11 6.6 0.0 10.4 7 3 0 7 7 7 1 Ankyrin repeat CNDH2_N PF06278.11 EGG22179.1 - 0.057 13.6 0.6 12 6.2 0.1 2.6 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal T6SS_HCP PF05638.12 EGG22179.1 - 0.086 13.2 0.6 10 6.5 0.0 3.0 2 1 1 3 3 3 0 Type VI secretion system effector, Hcp Ank_2 PF12796.7 EGG22180.1 - 1.9e-33 114.9 17.5 1.5e-09 38.3 0.0 8.0 3 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22180.1 - 3.2e-28 97.7 16.8 3e-05 24.5 0.0 11.6 10 3 3 13 13 13 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22180.1 - 8.8e-19 67.3 19.1 0.21 11.9 0.0 13.1 6 4 9 15 15 15 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22180.1 - 5.6e-12 44.7 4.5 6.9 7.6 0.0 11.9 15 0 0 15 15 15 1 Ankyrin repeat DUF5049 PF16468.5 EGG22180.1 - 9.1e-06 25.5 0.4 13 5.8 0.0 7.3 6 2 3 9 9 9 1 Domain of unknown function (DUF5049) DUF249 PF03158.13 EGG22180.1 - 0.0013 18.5 3.1 0.24 11.1 0.1 4.7 4 1 1 5 5 5 1 Multigene family 530 protein Ank PF00023.30 EGG22180.1 - 0.0087 16.5 2.8 1e+02 3.6 0.0 7.4 5 3 1 6 6 6 0 Ankyrin repeat Sec10 PF07393.11 EGG22180.1 - 0.037 12.4 0.1 0.061 11.7 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 Sec7 PF01369.20 EGG22181.1 - 1.9e-63 213.5 0.2 1e-62 211.0 0.2 2.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EGG22181.1 - 9.8e-32 110.0 7.2 9.8e-32 110.0 7.2 4.8 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGG22181.1 - 8.4e-24 83.2 5.8 3.4e-22 78.1 0.2 5.0 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DCB PF16213.5 EGG22181.1 - 2.7e-08 33.7 6.8 2.7e-08 33.7 6.8 3.3 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 U3snoRNP10 PF12397.8 EGG22181.1 - 0.042 14.2 10.3 0.12 12.8 0.0 5.1 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 DUF4368 PF14287.6 EGG22181.1 - 0.084 13.2 0.1 14 6.1 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) TPR_19 PF14559.6 EGG22182.1 - 0.0024 18.3 0.0 0.0064 17.0 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Ank_2 PF12796.7 EGG22183.1 - 2.5e-11 44.0 3.5 0.0001 22.8 0.0 5.6 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22183.1 - 1.1e-05 25.9 2.9 1.2 9.7 0.0 7.1 7 3 1 8 8 8 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22183.1 - 7.8e-05 22.9 1.7 4.2 7.8 0.0 5.9 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22183.1 - 0.00099 19.4 0.3 1.6e+02 3.4 0.0 7.0 7 0 0 7 7 7 0 Ankyrin repeat Methyltransf_12 PF08242.12 EGG22183.1 - 0.0063 17.2 2.3 4.9 8.0 0.1 2.9 2 0 0 2 2 2 2 Methyltransferase domain AAA_11 PF13086.6 EGG22184.1 - 5.9e-74 249.1 5.4 5.9e-74 249.1 5.4 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EGG22184.1 - 1.2e-61 207.9 2.2 8.5e-61 205.1 0.1 3.1 2 0 0 2 2 2 1 AAA domain SEN1_N PF12726.7 EGG22184.1 - 2.4e-30 105.5 4.5 2.4e-27 95.5 0.2 2.7 2 0 0 2 2 2 2 SEN1 N terminal AAA_30 PF13604.6 EGG22184.1 - 5.5e-11 42.6 0.0 1.5e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGG22184.1 - 1e-10 42.1 0.1 2.8e-10 40.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGG22184.1 - 1.6e-06 28.0 1.5 0.0025 17.6 0.0 3.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EGG22184.1 - 0.00085 19.2 0.0 1.2 9.0 0.0 3.0 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.6 EGG22184.1 - 0.002 18.4 0.3 0.03 14.6 0.0 2.9 1 1 1 2 2 2 1 AAA domain ATG16 PF08614.11 EGG22184.1 - 0.0051 17.1 3.5 0.0051 17.1 3.5 2.1 2 0 0 2 2 1 1 Autophagy protein 16 (ATG16) DUF3439 PF11921.8 EGG22184.1 - 0.029 14.3 1.5 0.11 12.5 1.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) KELK PF15796.5 EGG22184.1 - 0.034 14.6 4.6 0.1 13.1 4.6 1.9 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AAA_16 PF13191.6 EGG22184.1 - 0.06 13.7 0.0 0.31 11.4 0.0 2.3 2 0 0 2 2 1 0 AAA ATPase domain APG6_N PF17675.1 EGG22184.1 - 0.068 13.7 4.1 0.4 11.2 4.1 2.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 EGG22184.1 - 0.086 12.2 2.1 0.18 11.1 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA PF00004.29 EGG22184.1 - 0.11 12.9 0.0 0.69 10.3 0.0 2.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cob_adeno_trans PF01923.18 EGG22184.1 - 0.14 12.3 0.7 0.44 10.7 0.7 1.8 1 0 0 1 1 1 0 Cobalamin adenosyltransferase COG2 PF06148.11 EGG22184.1 - 0.14 12.2 5.0 0.32 11.1 3.6 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 EGG22184.1 - 0.18 11.8 3.7 0.7 9.9 3.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 EGG22184.1 - 0.2 11.9 5.4 1 9.6 5.4 2.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 EGG22184.1 - 0.21 12.1 2.6 1.3 9.6 2.6 2.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 EGG22184.1 - 0.38 11.0 4.1 2.3 8.5 4.1 2.4 1 0 0 1 1 1 0 Haemolysin XhlA DUF4164 PF13747.6 EGG22184.1 - 0.77 10.1 3.7 1.1 9.6 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Nup54 PF13874.6 EGG22184.1 - 1.2 9.2 6.4 6 7.0 5.4 2.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF745 PF05335.13 EGG22184.1 - 1.4 8.6 4.3 3.8 7.2 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 EGG22184.1 - 4.3 6.8 13.6 0.045 13.3 3.5 2.7 3 0 0 3 3 3 0 Exonuclease VII, large subunit ZapB PF06005.12 EGG22184.1 - 5.7 7.5 8.2 16 6.1 7.5 2.3 1 1 0 1 1 1 0 Cell division protein ZapB RSN1_7TM PF02714.15 EGG22185.1 - 1.2e-71 241.2 34.9 1.2e-71 241.2 34.9 2.9 2 1 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGG22185.1 - 9.6e-41 139.1 1.2 9.6e-41 139.1 1.2 3.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGG22185.1 - 3.9e-31 108.6 0.4 5.6e-31 108.1 0.4 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Sensor PF13796.6 EGG22185.1 - 0.016 15.2 0.1 0.016 15.2 0.1 3.2 3 2 0 3 3 3 0 Putative sensor UPF0242 PF06785.11 EGG22185.1 - 0.024 14.8 0.1 0.024 14.8 0.1 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DegT_DnrJ_EryC1 PF01041.17 EGG22185.1 - 0.25 10.6 0.2 1.4 8.1 0.1 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Tmemb_18A PF09771.9 EGG22185.1 - 5.2 7.5 8.1 15 6.0 0.5 3.2 2 2 0 2 2 2 0 Transmembrane protein 188 Nup160 PF11715.8 EGG22186.1 - 3e-36 125.2 15.2 1e-22 80.5 9.8 2.6 2 0 0 2 2 2 2 Nucleoporin Nup120/160 CcmE PF03100.15 EGG22186.1 - 5.7e-05 23.1 0.0 0.00021 21.3 0.0 2.0 1 0 0 1 1 1 1 CcmE GMC_oxred_N PF00732.19 EGG22187.1 - 1.1e-35 123.4 0.2 2.3e-35 122.4 0.2 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGG22187.1 - 3.6e-28 98.9 0.1 6.9e-28 98.0 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGG22187.1 - 0.0039 16.3 0.0 2 7.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EGG22187.1 - 0.0043 16.3 0.1 0.0078 15.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EGG22187.1 - 0.0061 16.2 0.2 0.12 12.0 0.2 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase DUF4248 PF14053.6 EGG22187.1 - 0.01 15.8 0.1 0.051 13.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) Lycopene_cycl PF05834.12 EGG22187.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 EGG22187.1 - 0.013 15.7 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG22187.1 - 0.12 11.5 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ank_4 PF13637.6 EGG22188.1 - 1.3e-45 153.2 10.4 9.2e-06 26.1 0.0 10.0 7 3 5 12 12 12 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG22188.1 - 4.5e-45 152.1 14.9 1.1e-07 32.3 0.0 7.8 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22188.1 - 6.3e-36 122.0 15.2 0.034 14.5 0.0 15.6 3 2 13 16 16 16 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22188.1 - 4.3e-23 78.9 14.0 0.84 10.4 0.0 16.2 15 3 3 18 18 18 2 Ankyrin repeat DUF5049 PF16468.5 EGG22188.1 - 5e-15 55.1 11.3 2.8 7.9 0.0 11.8 7 3 6 13 13 13 5 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22188.1 - 2e-12 47.0 0.0 3.9 8.1 0.0 10.8 4 4 4 8 8 8 2 Ankyrin repeat Vps39_2 PF10367.9 EGG22188.1 - 0.028 14.9 0.0 0.16 12.4 0.0 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 FBD PF08387.10 EGG22188.1 - 0.19 11.6 0.4 26 4.8 0.0 3.9 4 0 0 4 4 4 0 FBD DUF5099 PF17025.5 EGG22188.1 - 0.39 11.1 4.2 30 5.1 0.0 4.5 3 2 0 4 4 4 0 Domain of unknown function (DUF5099) EGF_2 PF07974.13 EGG22189.1 - 0.047 14.1 11.7 0.15 12.4 11.7 1.9 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.27 EGG22189.1 - 0.095 13.0 7.4 0.28 11.5 7.4 1.8 1 0 0 1 1 1 0 EGF-like domain AAA_16 PF13191.6 EGG22190.1 - 2.9e-06 27.8 0.2 1.1e-05 25.9 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG22190.1 - 7.7e-05 23.0 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG22190.1 - 0.00081 19.7 0.3 0.0099 16.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain DAP3 PF10236.9 EGG22190.1 - 0.0013 18.0 0.0 0.042 13.0 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 FtsK_SpoIIIE PF01580.18 EGG22190.1 - 0.004 16.5 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_25 PF13481.6 EGG22190.1 - 0.0045 16.6 0.0 2.4 7.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain GvpD PF07088.11 EGG22190.1 - 0.018 13.7 0.1 0.048 12.3 0.0 1.6 2 0 0 2 2 2 0 GvpD gas vesicle protein AAA_24 PF13479.6 EGG22190.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGG22190.1 - 0.081 12.7 0.0 0.17 11.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EGG22190.1 - 0.089 12.0 0.0 0.37 10.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Pro_CA PF00484.19 EGG22191.1 - 0.0043 17.3 0.0 0.0043 17.3 0.0 3.6 4 0 0 4 4 4 1 Carbonic anhydrase YL1 PF05764.13 EGG22191.1 - 0.3 11.2 33.1 0.022 14.9 18.8 2.9 3 0 0 3 3 3 0 YL1 nuclear protein CDC45 PF02724.14 EGG22191.1 - 0.39 8.9 23.5 0.033 12.5 17.7 1.8 2 0 0 2 2 2 0 CDC45-like protein Presenilin PF01080.17 EGG22191.1 - 5.8 5.6 21.5 0.83 8.3 16.2 2.0 2 0 0 2 2 2 0 Presenilin Ank_2 PF12796.7 EGG22192.1 - 8.8e-18 64.7 3.8 2.4e-06 28.0 0.0 5.3 5 1 3 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22192.1 - 2e-10 41.0 1.0 0.0096 16.5 0.1 6.5 5 4 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22192.1 - 1.6e-08 34.1 2.4 0.98 10.2 0.1 8.4 10 1 1 11 11 11 1 Ankyrin repeat Ank_5 PF13857.6 EGG22192.1 - 8.5e-06 26.0 13.6 0.22 11.9 0.1 7.0 5 2 2 7 7 7 3 Ankyrin repeats (many copies) RasGEF_N PF00618.20 EGG22192.1 - 0.052 13.8 1.9 0.56 10.5 0.9 3.0 2 0 0 2 2 2 0 RasGEF N-terminal motif Ank PF00023.30 EGG22192.1 - 0.081 13.4 1.0 1.9e+02 2.8 0.0 5.0 4 1 0 4 4 4 0 Ankyrin repeat Acetyltransf_1 PF00583.25 EGG22193.1 - 4.7e-05 23.6 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG22193.1 - 0.007 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3245 PF11595.8 EGG22193.1 - 6.9 7.1 6.8 0.59 10.6 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Clathrin PF00637.20 EGG22194.1 - 2e-21 76.4 29.2 2.2e-15 56.8 8.3 3.6 2 2 2 4 4 4 2 Region in Clathrin and VPS VPS11_C PF12451.8 EGG22194.1 - 5.1e-18 65.0 0.5 2.7e-17 62.7 0.5 2.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EGG22194.1 - 2.4e-06 27.5 7.4 4.8e-06 26.5 7.4 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 EGG22194.1 - 2e-05 24.4 8.6 4.1e-05 23.3 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG22194.1 - 0.00032 21.0 8.6 0.00032 21.0 8.6 1.8 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG22194.1 - 0.0022 18.0 3.9 0.0022 18.0 3.9 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG22194.1 - 0.0041 17.1 7.3 0.0095 15.9 7.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGG22194.1 - 0.032 14.5 6.8 0.094 13.0 6.8 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGG22194.1 - 0.11 12.6 1.5 0.97 9.5 0.7 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Acetyltransf_11 PF13720.6 EGG22194.1 - 0.14 12.6 1.3 6.4 7.3 0.1 3.0 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 zf-HC5HC2H PF13771.6 EGG22194.1 - 0.37 11.1 2.8 1 9.6 2.8 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain Vps39_2 PF10367.9 EGG22194.1 - 0.49 10.9 9.8 0.031 14.7 2.0 2.7 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.25 EGG22194.1 - 0.81 9.6 7.7 2 8.4 7.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG22194.1 - 1.1 9.2 5.7 2.6 8.0 5.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGG22194.1 - 1.9 8.6 8.6 5.8 7.1 4.5 2.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 IBP39 PF11422.8 EGG22195.1 - 0.04 13.7 1.7 0.61 9.8 0.1 2.0 1 1 1 2 2 2 0 Initiator binding protein 39 kDa YqzH PF14164.6 EGG22195.1 - 0.059 13.4 1.1 0.39 10.8 0.0 2.5 2 1 1 3 3 3 0 YqzH-like protein Acyl-CoA_dh_M PF02770.19 EGG22197.1 - 1.2e-11 44.6 0.0 2.4e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain TIG PF01833.24 EGG22197.1 - 7.5e-11 42.0 13.2 9.7e-06 25.6 1.2 3.9 3 0 0 3 3 3 3 IPT/TIG domain Acyl-CoA_dh_1 PF00441.24 EGG22197.1 - 2.2e-08 34.4 0.0 4.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 EGG22197.1 - 5.7e-08 32.5 0.1 1.3e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Phage_holin_7_1 PF16081.5 EGG22197.1 - 0.0013 18.9 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Acyl-CoA_dh_N PF02771.16 EGG22197.1 - 0.067 13.8 0.0 0.53 10.9 0.0 2.4 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, N-terminal domain EGF_2 PF07974.13 EGG22197.1 - 0.12 12.8 8.3 0.26 11.7 8.3 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGG22197.1 - 8.1 7.2 7.4 28 5.5 7.4 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF LRR_8 PF13855.6 EGG22199.1 - 0.003 17.3 14.0 0.075 12.8 0.2 5.2 6 1 1 7 7 7 2 Leucine rich repeat TIG PF01833.24 EGG22199.1 - 0.019 15.1 7.4 0.84 9.8 1.5 3.2 3 0 0 3 3 3 0 IPT/TIG domain LRR_4 PF12799.7 EGG22199.1 - 0.059 13.8 0.1 0.059 13.8 0.1 7.0 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) RNA_pol_A_bac PF01000.26 EGG22199.1 - 0.14 12.5 0.0 3.3 8.1 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb3/RpoA insert domain LRR_1 PF00560.33 EGG22199.1 - 2.1 9.2 8.9 39 5.4 0.2 5.9 4 1 0 4 4 4 0 Leucine Rich Repeat SAP PF02037.27 EGG22200.1 - 0.0001 21.9 0.1 0.00029 20.5 0.1 1.8 1 0 0 1 1 1 1 SAP domain DUF5131 PF07505.11 EGG22200.1 - 0.068 12.6 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) ArlS_N PF18719.1 EGG22200.1 - 0.082 13.1 1.4 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 ArlS sensor domain Glyco_hydro_63N PF16923.5 EGG22200.1 - 0.11 12.6 0.2 0.16 12.0 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 N-terminal domain VIR_N PF15912.5 EGG22200.1 - 0.41 10.2 9.5 0.54 9.8 9.5 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Ank_2 PF12796.7 EGG22201.1 - 3.8e-32 110.7 8.4 7.1e-07 29.7 0.1 6.4 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22201.1 - 1.1e-22 80.1 4.6 0.0019 18.7 0.0 9.3 6 2 5 11 11 11 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22201.1 - 4.2e-22 77.9 11.7 0.00025 21.3 0.1 11.9 5 4 7 13 13 13 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22201.1 - 1.1e-18 65.3 5.2 1.2 10.0 0.0 12.6 10 2 3 13 13 13 2 Ankyrin repeat Ank PF00023.30 EGG22201.1 - 6.7e-08 32.6 1.4 0.59 10.7 0.0 8.3 8 2 2 11 11 11 1 Ankyrin repeat DUF5049 PF16468.5 EGG22201.1 - 9.9e-06 25.4 5.3 8.3 6.4 0.0 6.9 5 2 3 8 8 8 2 Domain of unknown function (DUF5049) Ribosomal_L30 PF00327.20 EGG22201.1 - 0.08 12.9 0.0 34 4.4 0.0 3.2 3 0 0 3 3 3 0 Ribosomal protein L30p/L7e Ank_2 PF12796.7 EGG22203.1 - 3.6e-50 168.5 14.1 1.9e-09 37.9 0.0 7.8 3 2 6 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22203.1 - 2.9e-39 133.0 4.4 1.2e-05 25.8 0.0 10.3 9 3 0 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22203.1 - 1.5e-30 101.8 0.4 0.041 14.4 0.0 14.3 13 1 2 15 15 15 5 Ankyrin repeat Ank_5 PF13857.6 EGG22203.1 - 8.1e-29 99.3 3.9 0.00047 20.4 0.0 12.0 7 2 7 14 14 14 8 Ankyrin repeats (many copies) Ank PF00023.30 EGG22203.1 - 5.6e-11 42.4 0.0 0.97 10.0 0.0 9.9 4 3 4 8 8 8 1 Ankyrin repeat DUF5049 PF16468.5 EGG22203.1 - 5.1e-06 26.3 8.7 7.2 6.6 0.0 8.0 7 1 3 10 10 10 2 Domain of unknown function (DUF5049) CENP-B_dimeris PF09026.10 EGG22203.1 - 0.044 14.2 8.3 0.12 12.8 8.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tma16 PF11176.8 EGG22203.1 - 1.1 9.2 7.1 8 6.3 0.0 3.9 4 1 0 4 4 4 0 Translation machinery-associated protein 16 Cwf_Cwc_15 PF04889.12 EGG22203.1 - 2.8 7.6 7.8 5.9 6.5 7.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein adh_short PF00106.25 EGG22206.1 - 1.4e-37 129.1 0.2 2e-37 128.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG22206.1 - 6.1e-28 98.0 0.1 8.2e-28 97.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EGG22206.1 - 0.0061 16.5 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Flavodoxin_4 PF12682.7 EGG22206.1 - 0.077 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin Eno-Rase_NADH_b PF12242.8 EGG22206.1 - 0.11 12.2 0.0 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_M66 PF10462.9 EGG22207.1 - 9.9e-82 274.3 0.4 1.3e-81 273.9 0.4 1.1 1 0 0 1 1 1 1 Peptidase M66 Rib PF08428.10 EGG22207.1 - 0.00069 19.6 0.1 0.12 12.4 0.1 2.9 2 0 0 2 2 2 1 Rib/alpha-like repeat TagA PF12561.8 EGG22207.1 - 0.023 15.1 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 ToxR activated gene A lipoprotein domain Reprolysin_3 PF13582.6 EGG22207.1 - 0.052 14.1 0.2 0.1 13.1 0.2 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 EGG22207.1 - 0.11 11.1 0.1 0.17 10.4 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_4 PF13583.6 EGG22207.1 - 0.31 10.7 3.2 0.14 11.8 0.9 1.5 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like adh_short PF00106.25 EGG22208.1 - 8.3e-38 129.8 0.2 1.1e-37 129.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG22208.1 - 7.5e-29 100.9 0.0 1.1e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG22208.1 - 3.3e-05 23.9 0.1 5.2e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EGG22208.1 - 3.6e-05 23.4 0.7 0.11 12.1 0.2 2.1 2 0 0 2 2 2 2 NmrA-like family Eno-Rase_NADH_b PF12242.8 EGG22208.1 - 0.012 15.3 0.3 0.11 12.3 0.0 2.5 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_S24 PF00717.23 EGG22209.1 - 0.066 13.2 0.4 12 5.9 0.2 2.7 2 2 0 2 2 2 0 Peptidase S24-like tRNA_m1G_MT PF01746.21 EGG22212.1 - 1.8e-23 83.2 1.8 2.1e-23 83.1 0.1 1.9 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase RR_TM4-6 PF06459.12 EGG22212.1 - 2 8.2 20.0 4.7 7.0 9.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EGG22212.1 - 5.3 7.1 13.7 3.7 7.6 6.3 2.2 2 0 0 2 2 2 0 DDHD domain PAS_3 PF08447.12 EGG22213.1 - 1.2e-09 38.3 0.0 2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EGG22213.1 - 5.3e-05 23.4 0.1 0.00014 22.1 0.1 1.8 1 0 0 1 1 1 1 PAS domain Zn_clus PF00172.18 EGG22213.1 - 0.00081 19.5 4.5 0.0013 18.8 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EGG22213.1 - 0.091 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 PAS fold F-box-like PF12937.7 EGG22214.1 - 5.8e-05 22.9 0.1 0.00016 21.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG22214.1 - 0.01 15.7 0.3 0.029 14.3 0.3 1.8 1 0 0 1 1 1 0 F-box domain F-box_5 PF18511.1 EGG22214.1 - 0.025 14.2 0.1 0.59 9.8 0.2 2.4 2 0 0 2 2 2 0 F-box Ank_2 PF12796.7 EGG22215.1 - 9.4e-76 250.5 24.0 4.3e-10 40.0 0.1 12.7 4 4 11 15 15 15 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22215.1 - 6.6e-62 205.1 12.6 6.2e-07 29.8 0.0 16.4 7 4 7 15 15 15 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22215.1 - 3.4e-40 135.6 13.4 0.049 14.0 0.0 20.9 8 5 15 23 23 22 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22215.1 - 3e-37 122.4 8.6 0.53 11.0 0.0 23.5 24 1 2 26 26 25 4 Ankyrin repeat DUF5049 PF16468.5 EGG22215.1 - 1.3e-13 50.6 17.0 3 7.8 0.0 13.2 8 4 7 15 15 15 4 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22215.1 - 2.9e-11 43.3 0.0 12 6.6 0.0 13.0 9 5 2 11 11 10 1 Ankyrin repeat YAcAr PF10686.9 EGG22215.1 - 0.0057 16.6 3.9 20 5.2 0.1 4.7 4 0 0 4 4 4 0 YspA, cpYpsA-related SLOG family DUF3310 PF11753.8 EGG22215.1 - 0.01 16.0 1.1 20 5.5 0.0 5.0 3 1 0 3 3 3 0 Protein of unknwon function (DUF3310) Lipoprot_C PF08794.10 EGG22215.1 - 0.019 15.0 0.7 10 6.1 0.0 4.2 3 2 0 4 4 4 0 Lipoprotein GNA1870 C terminal like DUF3447 PF11929.8 EGG22215.1 - 0.023 14.6 25.0 0.095 12.7 0.2 10.1 3 2 9 13 13 13 0 Domain of unknown function (DUF3447) DUF3368 PF11848.8 EGG22215.1 - 0.061 13.1 0.1 26 4.7 0.1 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF3368) DUF4899 PF16240.5 EGG22215.1 - 0.08 12.1 2.0 1.6 7.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4899) Tox-PL-2 PF15643.6 EGG22215.1 - 0.085 13.0 3.6 3.3 7.9 0.4 3.7 3 0 0 3 3 3 0 Papain fold toxin 2 CNOT11 PF10155.9 EGG22215.1 - 0.96 9.6 5.3 0.67 10.1 0.1 3.1 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 11 Ank_2 PF12796.7 EGG22216.1 - 1.3e-47 160.2 21.8 2.6e-08 34.3 0.2 7.8 2 1 9 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22216.1 - 1.8e-32 111.3 8.9 2.2e-07 31.3 0.0 9.1 6 1 3 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22216.1 - 1.5e-23 82.6 4.4 0.00042 20.5 0.1 10.6 4 2 8 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22216.1 - 4e-18 63.6 9.0 2.7 8.8 0.0 13.0 15 0 0 15 15 15 5 Ankyrin repeat Ank PF00023.30 EGG22216.1 - 5.8e-07 29.7 0.5 73 4.1 0.0 9.2 5 2 2 7 7 7 0 Ankyrin repeat DUF5049 PF16468.5 EGG22216.1 - 2.7e-05 23.9 7.4 0.55 10.2 0.2 6.6 5 2 4 9 9 9 2 Domain of unknown function (DUF5049) YmaF PF12788.7 EGG22216.1 - 2 9.0 6.6 2.2 8.9 0.8 3.3 2 1 1 3 3 3 0 YmaF family Ank_2 PF12796.7 EGG22217.1 - 2e-38 130.9 11.0 1.2e-08 35.5 0.0 6.6 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22217.1 - 1.6e-29 101.9 3.2 2.9e-05 24.5 0.1 9.2 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22217.1 - 6.1e-22 77.4 5.3 0.11 12.9 0.0 11.0 4 2 8 12 12 12 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22217.1 - 1.1e-17 62.3 6.6 2.4 9.0 0.1 11.8 12 1 1 13 13 12 2 Ankyrin repeat DUF5049 PF16468.5 EGG22217.1 - 6e-08 32.5 4.9 6.5 6.7 0.0 6.9 5 2 3 8 8 8 4 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22217.1 - 5.3e-06 26.6 3.2 42 4.8 0.0 8.2 6 3 3 9 9 9 0 Ankyrin repeat DUF1415 PF07209.12 EGG22217.1 - 0.0037 17.0 0.5 1.4 8.7 0.0 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1415) DUF3447 PF11929.8 EGG22217.1 - 0.0058 16.6 11.1 0.56 10.2 0.2 5.5 2 1 5 7 7 7 1 Domain of unknown function (DUF3447) DUF2661 PF10860.8 EGG22217.1 - 0.023 14.8 0.8 0.084 13.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2661) Ndc80_HEC PF03801.13 EGG22217.1 - 0.074 12.7 0.1 21 4.7 0.0 3.7 3 1 0 4 4 4 0 HEC/Ndc80p family Mucin PF01456.17 EGG22217.1 - 0.082 12.9 11.0 0.15 12.1 11.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein LAMTOR PF15454.6 EGG22217.1 - 7.5 7.2 10.4 5.6 7.6 0.9 2.4 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Tugs PF17840.1 EGG22218.1 - 0.045 13.9 1.1 0.099 12.8 0.0 2.0 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain F-box-like PF12937.7 EGG22219.1 - 5.6e-05 22.9 0.1 0.0001 22.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG22219.1 - 0.008 16.0 0.3 0.019 14.8 0.3 1.7 1 0 0 1 1 1 1 F-box domain UPF0172 PF03665.13 EGG22220.1 - 8.4e-48 162.9 0.3 9.5e-48 162.8 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 EGG22220.1 - 3.8e-06 26.9 0.1 7.4e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Peptidase_M28 PF04389.17 EGG22221.1 - 0.011 15.5 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M28 DUF719 PF05334.13 EGG22221.1 - 0.11 12.6 3.3 1.8 8.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF719) SUZ PF12752.7 EGG22221.1 - 0.12 13.2 3.7 5.6 7.8 0.2 2.5 2 0 0 2 2 2 0 SUZ domain DRY_EERY PF09750.9 EGG22221.1 - 1.1 9.5 4.8 0.22 11.8 0.5 1.9 2 0 0 2 2 2 0 Alternative splicing regulator Coprogen_oxidas PF01218.18 EGG22222.1 - 6.5e-100 333.7 0.1 7.8e-100 333.4 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Ferrochelatase PF00762.19 EGG22223.1 - 6e-104 347.5 0.0 8.3e-104 347.1 0.0 1.2 1 0 0 1 1 1 1 Ferrochelatase Ank_2 PF12796.7 EGG22224.1 - 7.3e-17 61.7 1.4 7.7e-08 32.8 0.0 3.5 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22224.1 - 1.1e-12 48.2 3.6 0.00021 21.8 0.0 5.3 4 2 2 6 6 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22224.1 - 1.8e-12 47.2 4.9 0.0049 17.1 0.0 6.3 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22224.1 - 9.5e-09 34.8 2.6 3.2 8.6 0.0 7.5 6 1 2 8 8 8 2 Ankyrin repeat Ank PF00023.30 EGG22224.1 - 5.8e-05 23.4 0.2 8.1 7.1 0.0 5.3 2 2 2 4 4 4 2 Ankyrin repeat TPR_19 PF14559.6 EGG22225.1 - 1.4e-08 35.1 2.7 0.0085 16.6 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG22225.1 - 2e-05 24.7 8.0 0.00036 20.7 2.3 3.8 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGG22225.1 - 2.9e-05 23.8 4.4 0.053 13.6 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGG22225.1 - 3e-05 23.6 3.5 0.0043 16.7 1.3 4.2 4 1 1 5 5 5 1 TPR repeat TPR_1 PF00515.28 EGG22225.1 - 6.9e-05 22.5 9.9 0.0093 15.8 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG22225.1 - 0.00019 21.4 9.7 0.79 10.1 0.2 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG22225.1 - 0.0003 21.0 2.5 0.62 10.4 0.1 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG22225.1 - 0.0014 19.2 0.0 1.4 9.6 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG22225.1 - 0.022 15.5 0.0 12 7.0 0.0 4.1 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG22225.1 - 0.046 14.4 3.8 0.17 12.5 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGG22225.1 - 0.21 12.0 1.5 19 5.9 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LSM PF01423.22 EGG22226.1 - 4.2e-15 55.2 0.1 5.3e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGG22226.1 - 0.014 15.6 0.0 0.018 15.2 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 EGG22226.1 - 0.081 13.1 0.1 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Guanylate_cyc PF00211.20 EGG22227.1 - 1.8e-91 304.7 1.9 7.4e-48 162.6 1.2 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 EGG22227.1 - 0.0075 15.7 0.1 0.018 14.5 0.1 1.6 1 0 0 1 1 1 1 Heme NO binding associated CAP PF00188.26 EGG22228.1 - 2.8e-16 60.5 0.0 3.4e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rsm22 PF09243.10 EGG22229.1 - 1e-67 228.4 0.0 2.3e-67 227.2 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_11 PF08241.12 EGG22229.1 - 0.032 14.9 0.0 0.12 13.1 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain CART PF06373.11 EGG22229.1 - 1.1 9.5 2.6 46 4.3 0.6 3.0 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) MatE PF01554.18 EGG22230.1 - 1.4e-58 197.1 35.7 6.6e-31 107.1 6.1 2.8 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EGG22230.1 - 0.00086 19.4 3.9 0.00086 19.4 3.9 4.1 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain RXT2_N PF08595.11 EGG22230.1 - 1.8 8.6 14.2 3.3 7.7 14.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF3007 PF11460.8 EGG22230.1 - 2.2 8.6 4.7 1.6 9.0 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) MatE PF01554.18 EGG22231.1 - 2.4e-59 199.6 29.5 4.1e-31 107.8 5.4 2.4 2 0 0 2 2 2 2 MatE Importin_rep_6 PF18829.1 EGG22231.1 - 0.05 13.7 2.0 0.1 12.7 2.0 1.5 1 0 0 1 1 1 0 Importin repeat 6 PhoQ_Sensor PF08918.10 EGG22231.1 - 0.082 12.7 0.2 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 PhoQ Sensor CSF-1 PF05337.11 EGG22232.1 - 0.072 13.2 0.8 0.14 12.2 0.8 1.5 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) Ank_2 PF12796.7 EGG22234.1 - 2.5e-12 47.2 7.2 0.0012 19.4 0.1 4.6 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22234.1 - 4.2e-07 30.4 9.6 0.097 13.3 0.1 6.6 5 2 1 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22234.1 - 3e-06 27.1 5.2 3 8.7 0.0 7.3 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 EGG22234.1 - 5.6e-05 23.3 16.8 1.7 9.1 0.0 7.2 4 2 4 8 8 8 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG22235.1 - 2.2e-116 380.7 54.7 2.8e-12 47.1 0.1 19.6 7 4 14 21 21 21 19 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22235.1 - 1.1e-95 312.8 30.6 3.1e-06 27.6 0.0 24.1 18 6 2 23 23 23 18 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22235.1 - 1.5e-70 232.3 52.6 0.0029 17.9 0.1 33.1 7 4 30 37 37 37 21 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22235.1 - 7e-56 179.6 19.8 0.64 10.8 0.0 36.1 40 1 1 41 41 41 8 Ankyrin repeat DUF5049 PF16468.5 EGG22235.1 - 4.8e-23 80.8 40.3 1.4 8.8 0.1 22.6 17 6 11 28 28 28 9 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22235.1 - 1.1e-20 73.1 7.7 74 4.0 0.0 23.6 13 7 8 21 21 21 0 Ankyrin repeat UTP15_C PF09384.10 EGG22235.1 - 0.0012 18.6 0.0 30 4.3 0.0 6.5 4 3 3 8 8 8 0 UTP15 C terminal Insulin PF00049.18 EGG22235.1 - 0.025 15.6 2.5 3.4 8.7 0.0 4.0 4 0 0 4 4 4 0 Insulin/IGF/Relaxin family DUF3734 PF12536.8 EGG22235.1 - 0.045 14.1 5.8 33 4.9 0.0 7.1 5 4 2 8 8 8 0 Patatin phospholipase T6SS_HCP PF05638.12 EGG22235.1 - 0.51 10.8 16.3 12 6.3 0.2 5.9 4 2 1 6 6 6 0 Type VI secretion system effector, Hcp Ank_2 PF12796.7 EGG22236.1 - 1.3e-38 131.4 12.5 7.6e-10 39.2 0.0 6.9 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22236.1 - 1e-31 108.9 3.9 0.0002 21.8 0.0 9.2 5 4 6 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22236.1 - 6.4e-27 93.3 13.1 0.13 12.7 0.0 12.7 2 2 10 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22236.1 - 3.2e-22 76.2 1.9 0.069 13.7 0.0 12.9 14 0 0 14 14 14 3 Ankyrin repeat Ank PF00023.30 EGG22236.1 - 4.5e-09 36.4 0.0 41 4.9 0.0 9.6 3 3 4 7 7 7 0 Ankyrin repeat DUF5049 PF16468.5 EGG22236.1 - 1.3e-07 31.4 14.8 4.1 7.4 0.0 10.0 6 2 5 11 11 11 2 Domain of unknown function (DUF5049) Vps23_core PF09454.10 EGG22236.1 - 0.012 15.6 0.0 1.2e+02 2.7 0.0 6.0 4 2 3 7 7 7 0 Vps23 core domain Antimicrobial11 PF08106.11 EGG22236.1 - 0.067 13.2 2.5 0.12 12.4 2.5 1.4 1 0 0 1 1 1 0 Formaecin family Ank_2 PF12796.7 EGG22237.1 - 2.9e-34 117.5 7.3 1e-08 35.6 0.0 7.2 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22237.1 - 5.1e-31 106.3 6.2 0.0045 17.3 0.0 13.0 7 4 6 14 14 14 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22237.1 - 1.2e-30 105.4 7.2 9.8e-06 26.0 0.0 10.0 9 1 1 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22237.1 - 5.6e-22 75.5 9.1 2.8 8.8 0.1 14.4 16 0 0 16 16 16 3 Ankyrin repeat DUF5049 PF16468.5 EGG22237.1 - 3.2e-05 23.7 10.7 9.8 6.2 0.0 8.5 9 3 2 11 11 11 2 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22237.1 - 3.7e-05 24.0 0.4 53 4.5 0.0 7.7 6 3 1 7 7 7 0 Ankyrin repeat DUF3447 PF11929.8 EGG22237.1 - 0.00013 21.8 24.9 0.0016 18.4 0.3 7.1 5 2 3 8 8 8 2 Domain of unknown function (DUF3447) Baculo_19 PF04798.12 EGG22237.1 - 0.13 12.0 12.1 0.14 11.9 0.1 4.1 3 2 2 5 5 5 0 Baculovirus 19 kDa protein conserved region GGDEF PF00990.21 EGG22238.1 - 6.4e-36 123.5 0.5 1.2e-35 122.6 0.5 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Guanylate_cyc PF00211.20 EGG22238.1 - 0.0074 15.9 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ank_2 PF12796.7 EGG22239.1 - 1.8e-16 60.5 1.0 1e-06 29.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22239.1 - 5e-14 52.5 1.9 0.00019 22.0 0.1 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22239.1 - 1.3e-13 50.9 1.4 0.0031 17.8 0.0 5.4 2 1 4 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22239.1 - 2.4e-08 33.6 1.5 18 6.3 0.0 7.3 7 1 1 8 8 8 2 Ankyrin repeat DUF5049 PF16468.5 EGG22239.1 - 7.3e-06 25.8 0.2 0.1 12.5 0.1 4.2 4 1 1 5 5 5 2 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22239.1 - 0.0024 18.3 0.2 36 5.0 0.0 5.3 3 2 1 4 4 4 0 Ankyrin repeat Senescence_reg PF04520.13 EGG22239.1 - 0.027 15.3 0.0 0.077 13.8 0.0 1.7 2 0 0 2 2 2 0 Senescence regulator GGDEF PF00990.21 EGG22240.1 - 3.3e-36 124.5 0.8 5.9e-36 123.6 0.8 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Guanylate_cyc PF00211.20 EGG22240.1 - 0.0017 18.0 0.1 0.0033 17.1 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain putAbiC PF16872.5 EGG22240.1 - 0.28 11.9 5.4 0.2 12.4 2.2 2.4 3 0 0 3 3 3 0 Putative phage abortive infection protein Ank_2 PF12796.7 EGG22241.1 - 4.3e-58 193.9 24.7 1.8e-11 44.4 0.2 8.3 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22241.1 - 1.9e-49 165.4 8.1 1.5e-05 25.5 0.0 11.1 8 2 4 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22241.1 - 4.2e-38 128.9 13.9 0.016 15.5 0.0 16.4 1 1 15 17 17 17 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22241.1 - 2.3e-28 95.1 3.3 6 7.8 0.0 16.8 18 1 1 19 19 19 4 Ankyrin repeat DUF5049 PF16468.5 EGG22241.1 - 1.7e-21 75.9 18.1 0.33 10.9 0.0 14.0 2 1 13 15 15 15 8 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22241.1 - 7e-13 48.4 1.7 18 6.0 0.0 12.7 5 3 5 10 10 10 1 Ankyrin repeat DUF5099 PF17025.5 EGG22241.1 - 0.027 14.9 0.6 17 5.8 0.1 4.4 2 2 1 3 3 3 0 Domain of unknown function (DUF5099) HTH_10 PF04967.12 EGG22241.1 - 0.029 14.2 2.2 14 5.6 0.0 4.7 6 0 0 6 6 6 0 HTH DNA binding domain ADH_N PF08240.12 EGG22242.1 - 1.2e-27 96.0 4.1 2.3e-27 95.0 4.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGG22242.1 - 6.2e-21 74.7 0.0 1.4e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGG22242.1 - 0.0055 17.8 0.0 0.01 16.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Vps54_N PF10475.9 EGG22244.1 - 8.6e-96 320.6 3.5 8.6e-96 320.6 3.5 2.2 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EGG22244.1 - 1.4e-55 188.6 3.2 2.4e-55 187.9 0.8 2.4 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) BSP_II PF05432.11 EGG22244.1 - 0.0032 17.2 20.6 0.0053 16.5 20.6 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) COG2 PF06148.11 EGG22244.1 - 0.0077 16.3 3.2 0.052 13.6 0.1 3.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 EGG22244.1 - 0.014 15.3 0.9 0.014 15.3 0.9 3.8 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain COMMD1_N PF17221.3 EGG22244.1 - 0.029 14.6 2.1 4.1 7.8 0.0 3.8 3 0 0 3 3 3 0 COMMD1 N-terminal domain DUF3502 PF12010.8 EGG22244.1 - 0.31 11.7 9.8 1.4 9.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) Pox_Ag35 PF03286.14 EGG22244.1 - 0.86 9.4 16.4 2.5 7.8 16.4 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Stomoxyn PF11585.8 EGG22244.1 - 1.6 8.8 5.6 9.1 6.4 1.2 2.8 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn CDC45 PF02724.14 EGG22244.1 - 2.2 6.5 15.9 3.6 5.7 15.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Ank_4 PF13637.6 EGG22245.1 - 0.00029 21.3 0.0 0.00046 20.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG22245.1 - 0.013 16.1 0.1 0.019 15.5 0.1 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) GGDEF PF00990.21 EGG22247.1 - 4.6e-31 107.7 1.3 4.6e-31 107.7 1.3 1.8 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain Guanylate_cyc PF00211.20 EGG22247.1 - 0.0065 16.1 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DXPR_C PF13288.6 EGG22247.1 - 0.015 15.6 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 DXP reductoisomerase C-terminal domain Dmrt1 PF12374.8 EGG22247.1 - 0.2 12.1 1.5 1 9.8 1.0 2.3 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 putAbiC PF16872.5 EGG22247.1 - 0.5 11.1 6.4 0.36 11.5 3.1 2.6 3 0 0 3 3 3 0 Putative phage abortive infection protein Ank_2 PF12796.7 EGG22248.1 - 2.7e-63 210.5 12.1 5.2e-12 46.2 0.0 7.8 1 1 7 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22248.1 - 3.4e-49 164.6 7.3 3.7e-06 27.4 0.0 9.8 4 2 5 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22248.1 - 2e-42 142.7 16.8 0.01 16.1 0.1 14.6 1 1 14 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22248.1 - 4.9e-40 131.0 0.4 1.3 9.9 0.0 15.4 16 0 0 16 16 16 10 Ankyrin repeat DUF5049 PF16468.5 EGG22248.1 - 8.1e-25 86.5 11.7 0.83 9.6 0.0 13.5 3 1 11 14 14 14 8 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22248.1 - 3.1e-18 65.3 0.1 8.9 7.0 0.0 13.6 5 2 8 13 13 13 2 Ankyrin repeat DUF5099 PF17025.5 EGG22248.1 - 0.001 19.4 0.0 51 4.3 0.0 5.2 2 2 2 5 5 5 0 Domain of unknown function (DUF5099) Ins_allergen_rp PF06757.13 EGG22248.1 - 0.019 15.0 0.0 16 5.4 0.0 4.3 4 1 0 4 4 4 0 Insect allergen related repeat, nitrile-specifier detoxification UTP15_C PF09384.10 EGG22248.1 - 0.033 13.9 0.0 13 5.5 0.0 3.8 2 2 2 4 4 4 0 UTP15 C terminal SBP_bac_6 PF13343.6 EGG22248.1 - 0.075 12.4 2.8 1.8 7.9 0.1 3.1 2 1 1 3 3 3 0 Bacterial extracellular solute-binding protein BMC PF00936.19 EGG22248.1 - 0.23 11.5 2.3 47 4.1 0.0 4.6 5 1 1 6 6 6 0 BMC domain APOBEC4_like PF18774.1 EGG22248.1 - 0.87 9.5 3.6 24 4.9 0.1 3.8 3 1 1 4 4 4 0 APOBEC4-like -AID/APOBEC-deaminase GGDEF PF00990.21 EGG22249.1 - 3.7e-36 124.3 0.8 7.2e-36 123.4 0.8 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Guanylate_cyc PF00211.20 EGG22249.1 - 0.003 17.2 0.1 0.0052 16.4 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain putAbiC PF16872.5 EGG22249.1 - 0.18 12.5 4.7 0.14 12.9 1.7 2.4 3 0 0 3 3 3 0 Putative phage abortive infection protein dCMP_cyt_deam_1 PF00383.23 EGG22250.1 - 4.9e-11 42.4 0.4 9.1e-11 41.5 0.4 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGG22250.1 - 2.8e-10 40.1 0.1 4.1e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EGG22250.1 - 0.0016 18.6 0.3 1.1 9.4 0.0 2.3 2 0 0 2 2 2 2 Bd3614-like deaminase DIM PF08194.12 EGG22250.1 - 0.0045 17.2 0.2 0.012 15.8 0.2 1.7 1 0 0 1 1 1 1 DIM protein CBM49 PF09478.10 EGG22250.1 - 0.0096 16.2 1.3 0.023 15.0 0.7 1.9 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 Ank_2 PF12796.7 EGG22251.1 - 1.8e-28 99.0 0.8 4.3e-11 43.2 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22251.1 - 2.3e-22 79.0 0.3 1.5e-05 25.4 0.1 5.4 2 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22251.1 - 1e-17 63.9 2.8 0.0027 18.0 0.0 8.1 3 1 6 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22251.1 - 4.2e-17 60.5 1.9 0.53 11.0 0.0 9.1 9 1 1 10 10 10 4 Ankyrin repeat DUF5049 PF16468.5 EGG22251.1 - 2.4e-10 40.2 0.6 0.31 11.0 0.1 6.1 3 1 3 6 6 6 3 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22251.1 - 3.4e-05 24.1 0.2 55 4.5 0.0 6.5 5 1 1 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 EGG22252.1 - 8e-29 100.1 3.8 5.1e-09 36.6 0.0 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22252.1 - 4.1e-25 87.8 1.9 3.6e-06 27.4 0.0 6.5 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22252.1 - 8.3e-21 73.8 0.3 0.034 14.5 0.0 8.5 2 1 7 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22252.1 - 7.5e-15 53.6 1.5 8.8 7.3 0.0 10.3 9 2 2 11 11 11 3 Ankyrin repeat Ank PF00023.30 EGG22252.1 - 2.5e-06 27.7 0.1 30 5.3 0.0 6.8 3 1 3 6 6 6 0 Ankyrin repeat DUF5049 PF16468.5 EGG22252.1 - 3.9e-06 26.6 0.1 9 6.3 0.0 5.3 4 1 2 6 6 6 2 Domain of unknown function (DUF5049) DUF3447 PF11929.8 EGG22252.1 - 0.036 14.0 6.4 0.86 9.6 0.2 4.3 1 1 4 5 5 5 0 Domain of unknown function (DUF3447) PT PF04886.12 EGG22254.1 - 6.2e-27 92.9 260.5 2e-06 27.2 21.6 10.9 2 1 3 5 5 5 2 PT repeat RhoGAP PF00620.27 EGG22255.1 - 1.1e-20 74.0 0.0 1.1e-20 74.0 0.0 2.4 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.23 EGG22255.1 - 2.1e-11 43.9 2.5 3.5e-11 43.2 0.3 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Mito_carr PF00153.27 EGG22256.1 - 1.3e-70 233.4 1.9 1.1e-23 83.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ank_4 PF13637.6 EGG22257.1 - 1.6e-33 114.6 2.3 5.2e-08 33.3 0.2 6.3 4 3 1 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG22257.1 - 5.1e-33 113.5 3.0 1.5e-09 38.3 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22257.1 - 5.2e-27 93.6 7.3 7.1e-06 26.2 0.3 8.6 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22257.1 - 3.7e-20 69.9 0.3 0.56 10.9 0.0 9.3 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 EGG22257.1 - 6.7e-09 35.8 0.0 5.8 7.5 0.0 7.6 2 2 4 6 6 6 2 Ankyrin repeat DUF5049 PF16468.5 EGG22257.1 - 1.9e-08 34.0 5.6 0.45 10.4 0.1 7.2 5 2 4 9 9 9 2 Domain of unknown function (DUF5049) DUF3447 PF11929.8 EGG22257.1 - 0.001 18.9 3.9 1.8 8.6 0.4 3.7 2 2 1 3 3 3 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EGG22258.1 - 9.1e-50 167.2 14.6 1.1e-12 48.3 0.1 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22258.1 - 8.2e-27 92.9 6.1 0.0052 17.1 0.0 8.8 1 1 8 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22258.1 - 4.7e-26 90.8 0.6 5.9e-06 26.7 0.1 5.5 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22258.1 - 1.7e-23 80.1 0.5 0.22 12.2 0.0 8.8 7 1 1 8 8 8 5 Ankyrin repeat DUF5049 PF16468.5 EGG22258.1 - 1.6e-15 56.8 5.7 0.47 10.4 0.0 7.3 4 2 3 7 7 7 6 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22258.1 - 1.6e-10 40.9 0.3 0.94 10.0 0.0 7.6 3 2 5 8 8 8 2 Ankyrin repeat DDE_2 PF02914.15 EGG22258.1 - 0.097 12.4 0.0 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage Mu transposase DUF4747 PF15931.5 EGG22258.1 - 0.099 12.3 1.0 35 3.9 0.0 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF4747) Ank_2 PF12796.7 EGG22259.1 - 2.4e-69 229.9 28.5 1.9e-11 44.4 0.1 7.3 2 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22259.1 - 2.6e-49 165.0 13.0 2e-06 28.2 0.0 8.9 3 1 7 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22259.1 - 6e-41 138.0 6.4 0.0031 17.8 0.0 12.6 3 2 10 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22259.1 - 5.3e-35 115.5 1.4 1.5 9.6 0.0 14.2 13 1 1 14 14 14 9 Ankyrin repeat DUF5049 PF16468.5 EGG22259.1 - 4.9e-20 71.2 12.3 0.61 10.0 0.0 10.1 3 1 7 10 10 10 7 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22259.1 - 1.1e-13 50.9 0.1 9.3 6.9 0.1 10.8 3 1 4 7 7 7 3 Ankyrin repeat UTP15_C PF09384.10 EGG22259.1 - 0.0087 15.8 0.9 14 5.3 0.0 3.9 2 1 3 5 5 5 1 UTP15 C terminal DUF5099 PF17025.5 EGG22259.1 - 0.024 15.1 0.0 46 4.5 0.0 4.5 1 1 3 4 4 4 0 Domain of unknown function (DUF5099) DUF249 PF03158.13 EGG22259.1 - 0.04 13.6 5.4 21 4.8 0.0 5.2 2 1 6 8 8 8 0 Multigene family 530 protein RHD_DNA_bind PF00554.22 EGG22259.1 - 1 9.3 3.5 62 3.5 0.1 4.1 1 1 6 7 7 7 0 Rel homology DNA-binding domain zf-TRAF PF02176.18 EGG22260.1 - 2.5e-11 44.1 33.4 7.6e-08 32.9 5.9 3.9 2 2 2 4 4 4 2 TRAF-type zinc finger Sina PF03145.16 EGG22260.1 - 6.3e-11 42.6 17.2 1.8e-07 31.3 3.7 3.3 1 1 2 3 3 3 2 Seven in absentia protein family zf-TRAF_2 PF15965.5 EGG22260.1 - 7.2e-05 23.2 23.3 0.0011 19.4 6.4 3.1 1 1 1 2 2 2 2 TRAF-like zinc-finger zf-C3HC4_2 PF13923.6 EGG22260.1 - 0.0012 18.6 10.1 0.0012 18.6 10.1 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG22260.1 - 0.0014 18.4 10.0 0.0014 18.4 10.0 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG22260.1 - 0.0015 18.8 9.6 0.0015 18.8 9.6 3.9 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 EGG22260.1 - 0.0053 16.6 10.0 0.0053 16.6 10.0 3.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG22260.1 - 0.013 15.5 7.8 0.013 15.5 7.8 3.3 3 0 0 3 3 3 0 RING-type zinc-finger zf-U11-48K PF05253.12 EGG22260.1 - 1.5 8.9 7.7 0.7 9.9 0.5 3.7 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger Pox_F15 PF04596.12 EGG22261.1 - 0.028 14.2 0.2 0.028 14.2 0.2 2.5 3 0 0 3 3 3 0 Poxvirus protein F15 YihI PF04220.12 EGG22261.1 - 0.11 12.3 0.2 0.22 11.2 0.2 1.5 1 0 0 1 1 1 0 Der GTPase activator (YihI) zf-RING_UBOX PF13445.6 EGG22261.1 - 4.8 7.3 11.3 12 6.1 11.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DARPP-32 PF05395.12 EGG22262.1 - 0.00046 20.4 2.6 0.00073 19.8 2.6 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 Cwf_Cwc_15 PF04889.12 EGG22262.1 - 0.035 13.8 5.9 0.054 13.2 5.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4611 PF15387.6 EGG22262.1 - 0.046 13.9 3.8 0.078 13.2 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) EBV-NA3 PF05009.12 EGG22262.1 - 0.051 13.1 1.4 0.071 12.6 1.4 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CobT PF06213.12 EGG22262.1 - 0.14 11.5 4.5 0.22 10.9 4.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MPP6 PF10175.9 EGG22262.1 - 0.15 12.6 6.0 0.25 11.8 6.0 1.3 1 0 0 1 1 1 0 M-phase phosphoprotein 6 CDC45 PF02724.14 EGG22262.1 - 0.21 9.8 1.6 0.25 9.6 1.6 1.1 1 0 0 1 1 1 0 CDC45-like protein C1_2 PF03107.16 EGG22262.1 - 1.2 9.5 14.2 0.34 11.2 0.7 3.7 3 1 0 3 3 3 0 C1 domain PBP1_TM PF14812.6 EGG22262.1 - 3.2 8.2 6.6 8.4 6.8 6.6 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PTPRCAP PF15713.5 EGG22262.1 - 3.4 7.9 10.2 0.31 11.3 5.7 1.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated zf-RING_UBOX PF13445.6 EGG22263.1 - 0.0021 18.1 0.4 0.0021 18.1 0.4 2.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-TRAF PF02176.18 EGG22263.1 - 0.0038 17.9 0.5 0.0038 17.9 0.5 2.1 2 1 1 3 3 3 1 TRAF-type zinc finger zf-C3HC4 PF00097.25 EGG22263.1 - 0.0092 15.8 4.0 0.0095 15.8 0.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EGG22263.1 - 0.029 14.8 4.8 0.11 13.0 4.8 2.0 1 1 0 1 1 1 0 TRAF-like zinc-finger zf-RAG1 PF10426.9 EGG22263.1 - 0.048 13.8 0.3 0.55 10.4 0.0 2.4 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain zf-RING_5 PF14634.6 EGG22263.1 - 2.7 8.0 7.5 0.29 11.1 1.1 2.3 2 1 0 2 2 2 0 zinc-RING finger domain CSRNP_N PF16019.5 EGG22264.1 - 0.14 12.0 3.4 0.086 12.7 2.0 1.4 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Cofilin_ADF PF00241.20 EGG22265.1 - 1.6e-07 31.1 0.0 3.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CDT1 PF08839.11 EGG22265.1 - 0.032 14.5 0.2 0.14 12.4 0.0 2.0 1 1 1 2 2 2 0 DNA replication factor CDT1 like Peptidase_M3 PF01432.20 EGG22266.1 - 5.9e-125 418.1 1.4 8.6e-125 417.6 1.4 1.3 1 0 0 1 1 1 1 Peptidase family M3 BAR_3 PF16746.5 EGG22266.1 - 0.00049 19.9 4.4 0.0068 16.1 4.4 2.6 1 1 0 1 1 1 1 BAR domain of APPL family PdxJ PF03740.13 EGG22266.1 - 0.078 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ DNA_pol_phi PF04931.13 EGG22267.1 - 0.26 9.4 2.3 0.4 8.7 2.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EGG22267.1 - 2.4 7.4 6.0 3.7 6.8 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EGG22267.1 - 7.3 7.0 13.0 5.1 7.5 11.1 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ank_2 PF12796.7 EGG22268.1 - 0.06 13.9 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG22268.1 - 0.099 13.2 0.1 4.2 8.3 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Peptidase_M3 PF01432.20 EGG22269.1 - 1.9e-21 76.9 0.7 4.8e-21 75.5 0.7 1.6 1 1 0 1 1 1 1 Peptidase family M3 Phage_tail_X PF05489.12 EGG22269.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Phage Tail Protein X Mcm10 PF09332.11 EGG22269.1 - 0.24 10.8 0.0 0.32 10.4 0.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor CytochromB561_N PF09786.9 EGG22270.1 - 5.8e-12 45.4 19.0 7.2e-09 35.2 0.8 2.1 2 0 0 2 2 2 2 Cytochrome B561, N terminal Adap_comp_sub PF00928.21 EGG22271.1 - 3.9e-74 249.4 0.1 4.6e-74 249.1 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGG22271.1 - 0.16 11.9 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Maf1 PF09174.10 EGG22272.1 - 6.8e-62 208.7 2.7 1.1e-61 208.0 2.7 1.3 1 0 0 1 1 1 1 Maf1 regulator Ank_2 PF12796.7 EGG22274.1 - 2.2e-19 69.8 2.8 7.9e-07 29.6 0.5 5.5 1 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22274.1 - 1.4e-17 63.8 1.7 0.00066 20.2 0.0 7.0 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22274.1 - 1.6e-10 41.0 6.5 0.023 15.0 0.2 7.6 5 2 4 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22274.1 - 7.4e-08 32.1 9.0 4.3 8.2 0.0 9.6 11 1 1 12 12 12 2 Ankyrin repeat Ank_2 PF12796.7 EGG22275.1 - 5.7e-50 167.8 15.5 3.8e-09 37.0 0.1 7.7 1 1 8 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22275.1 - 1.7e-45 152.8 11.6 3.9e-06 27.3 0.0 10.6 9 3 3 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22275.1 - 3.5e-27 94.1 14.6 0.012 15.9 0.0 14.3 3 2 12 15 15 15 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22275.1 - 6e-25 84.6 11.9 1.1 10.0 0.0 15.9 17 2 1 18 18 18 6 Ankyrin repeat DUF5049 PF16468.5 EGG22275.1 - 5.5e-11 42.2 7.7 3.3 7.7 0.0 11.3 8 3 5 13 13 13 2 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22275.1 - 6.1e-09 35.9 7.9 6.6 7.4 0.0 12.0 6 3 5 11 11 11 1 Ankyrin repeat Ank_2 PF12796.7 EGG22276.1 - 8.2e-52 173.7 17.8 6.4e-11 42.7 0.1 7.7 3 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22276.1 - 3.2e-45 151.9 21.0 9.7e-07 29.2 0.0 10.0 3 2 8 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22276.1 - 1e-37 127.7 14.3 0.012 15.9 0.1 13.2 3 2 10 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22276.1 - 4.1e-35 115.8 6.2 0.28 11.8 0.0 14.0 11 3 3 14 14 14 11 Ankyrin repeat DUF5049 PF16468.5 EGG22276.1 - 1.9e-15 56.5 9.7 0.32 10.9 0.0 10.0 5 3 5 10 10 10 5 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22276.1 - 2e-11 43.8 2.5 13 6.4 0.1 11.4 5 2 6 11 11 11 1 Ankyrin repeat FBD PF08387.10 EGG22276.1 - 0.0099 15.7 1.1 31 4.5 0.1 5.7 6 0 0 6 6 6 0 FBD Lipoprot_C PF08794.10 EGG22276.1 - 0.013 15.5 1.6 7.2 6.6 0.0 4.0 3 2 1 4 4 4 0 Lipoprotein GNA1870 C terminal like DUF3447 PF11929.8 EGG22276.1 - 0.014 15.3 16.4 1.7 8.7 0.1 6.5 1 1 5 7 7 7 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EGG22277.1 - 1.8e-90 297.6 37.5 1.4e-10 41.6 0.1 13.5 4 3 12 16 16 16 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22277.1 - 4e-64 212.2 34.1 1.7e-05 25.3 0.0 17.6 7 4 11 20 20 20 20 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22277.1 - 1.6e-53 178.1 40.5 0.011 16.0 0.1 25.6 9 5 19 28 28 27 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22277.1 - 2.2e-45 147.4 19.4 0.45 11.2 0.0 25.8 23 3 4 27 27 26 9 Ankyrin repeat DUF5049 PF16468.5 EGG22277.1 - 5.3e-19 67.9 32.0 0.99 9.4 0.0 17.9 14 4 7 21 21 20 6 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22277.1 - 3.3e-14 52.6 17.7 19 5.9 0.0 19.6 14 7 8 22 22 21 0 Ankyrin repeat Glyoxalase_3 PF13468.6 EGG22277.1 - 0.0036 17.5 2.3 1.4 9.0 0.0 3.6 4 0 0 4 4 4 2 Glyoxalase-like domain Ribosomal_L30 PF00327.20 EGG22277.1 - 0.034 14.0 0.0 0.34 10.8 0.0 2.9 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e SapB_1 PF05184.15 EGG22277.1 - 0.12 12.4 0.1 46 4.2 0.0 4.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 Furin-like PF00757.20 EGG22277.1 - 0.2 11.5 2.6 5.6 6.8 0.3 2.5 2 0 0 2 2 2 0 Furin-like cysteine rich region FliG_N PF14842.6 EGG22277.1 - 0.21 12.2 0.7 24 5.5 0.1 2.6 2 0 0 2 2 2 0 FliG N-terminal domain DUF2101 PF09874.9 EGG22277.1 - 0.23 11.1 0.6 19 4.9 0.1 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) Ank_2 PF12796.7 EGG22278.1 - 1.1e-09 38.8 0.1 6.5e-09 36.3 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22278.1 - 6.2e-09 36.2 0.4 3.7e-05 24.2 0.1 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22278.1 - 4.6e-07 30.0 0.0 0.063 13.6 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22278.1 - 6.9e-07 29.1 0.0 0.38 11.4 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EGG22278.1 - 0.03 14.8 0.0 31 5.3 0.0 3.2 2 2 1 3 3 3 0 Ankyrin repeat ADH_N PF08240.12 EGG22279.1 - 6.3e-28 96.8 5.5 1.2e-27 95.9 5.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGG22279.1 - 2.2e-19 69.7 0.1 4.5e-19 68.7 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGG22279.1 - 0.00034 21.7 0.0 0.00078 20.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Transketolase_C PF02780.20 EGG22282.1 - 2.6e-44 150.1 0.2 4.6e-44 149.3 0.2 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EGG22282.1 - 7.6e-42 143.0 0.0 1.4e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 EGG22282.1 - 0.00025 21.3 0.0 0.00051 20.3 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Glycos_transf_1 PF00534.20 EGG22283.1 - 4.7e-08 32.7 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGG22283.1 - 1.6e-05 25.4 0.0 3.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF4766 PF15973.5 EGG22283.1 - 0.034 14.7 8.1 0.49 11.0 1.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) Glyco_trans_1_2 PF13524.6 EGG22283.1 - 0.071 13.5 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 RVT_3 PF13456.6 EGG22284.1 - 0.0024 17.6 0.1 0.0036 17.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like FancD2 PF14631.6 EGG22285.1 - 7e-78 262.4 21.0 1.4e-65 221.6 13.5 6.6 5 2 1 6 6 6 4 Fanconi anaemia protein FancD2 nuclease NPR3 PF03666.13 EGG22285.1 - 0.002 17.0 6.8 0.002 17.0 6.8 4.7 3 1 1 4 4 4 1 Nitrogen Permease regulator of amino acid transport activity 3 Ank_2 PF12796.7 EGG22286.1 - 1e-10 42.0 0.4 4.5e-08 33.6 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22286.1 - 4.7e-07 30.2 0.1 0.011 16.3 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22286.1 - 3e-06 27.4 0.3 0.14 12.6 0.0 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22286.1 - 1.1e-05 25.4 0.1 1.6 9.6 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EGG22286.1 - 0.072 13.6 0.2 3.4 8.3 0.1 3.6 1 1 1 2 2 2 0 Ankyrin repeat CH PF00307.31 EGG22287.1 - 4.6e-38 129.8 11.4 1.8e-14 53.8 0.3 6.0 6 0 0 6 6 6 4 Calponin homology (CH) domain PH PF00169.29 EGG22287.1 - 4.1e-16 59.4 0.1 1.5e-15 57.6 0.1 2.0 1 0 0 1 1 1 1 PH domain FERM_f0 PF16511.5 EGG22287.1 - 1.4e-14 54.1 0.3 7e-11 42.3 0.0 2.8 2 0 0 2 2 2 2 N-terminal or F0 domain of Talin-head FERM DUF3430 PF11912.8 EGG22288.1 - 2.8e-21 76.5 18.6 3.4e-21 76.3 18.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) YfaZ PF07437.11 EGG22288.1 - 0.0001 22.0 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 YfaZ precursor Ank_2 PF12796.7 EGG22289.1 - 3e-31 107.9 4.7 2.6e-11 44.0 0.6 4.7 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22289.1 - 6.5e-28 96.4 8.4 0.00016 21.9 0.2 8.7 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22289.1 - 2.8e-25 88.3 11.8 3.5e-05 24.2 0.0 6.9 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22289.1 - 8.2e-21 71.9 2.4 0.51 11.1 0.0 9.5 9 1 1 10 10 10 5 Ankyrin repeat DUF5049 PF16468.5 EGG22289.1 - 2.4e-10 40.1 4.9 0.1 12.5 0.0 6.9 3 1 4 7 7 7 3 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22289.1 - 4.2e-07 30.1 0.1 12 6.6 0.1 7.0 3 2 3 6 6 6 2 Ankyrin repeat PyrI PF01948.18 EGG22289.1 - 0.038 14.2 0.0 5.1 7.4 0.0 3.4 2 2 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain Insulin PF00049.18 EGG22289.1 - 0.15 13.1 0.5 0.51 11.4 0.1 2.1 2 0 0 2 2 2 0 Insulin/IGF/Relaxin family DUF3430 PF11912.8 EGG22290.1 - 2e-09 37.8 13.9 2e-09 37.8 13.9 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3430) MRAP PF15183.6 EGG22290.1 - 0.38 10.7 3.3 0.94 9.5 3.3 1.6 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family HSD3 PF15244.6 EGG22290.1 - 4.1 6.8 6.9 0.31 10.5 1.4 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 7, or HSD3 Ank_2 PF12796.7 EGG22291.1 - 7e-35 119.5 2.9 1.1e-08 35.6 0.1 4.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22291.1 - 2.9e-16 59.3 3.0 0.024 15.0 0.0 7.8 3 2 5 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22291.1 - 4.4e-16 59.0 0.8 0.00058 20.4 0.1 5.9 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22291.1 - 2.1e-13 49.1 0.2 3.1 8.7 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat DUF5049 PF16468.5 EGG22291.1 - 1.7e-05 24.6 0.2 9 6.3 0.0 5.1 3 1 2 5 5 5 3 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22291.1 - 0.00021 21.6 1.5 32 5.2 0.0 6.0 3 2 2 5 5 5 0 Ankyrin repeat Ank_2 PF12796.7 EGG22292.1 - 1.8e-07 31.6 0.0 2.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22292.1 - 0.00017 21.8 0.0 0.00039 20.7 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22292.1 - 0.00033 21.1 0.0 0.0009 19.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22292.1 - 0.00046 20.4 0.0 1.4 9.7 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EGG22292.1 - 0.078 13.5 0.0 6.1 7.5 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeat p450 PF00067.22 EGG22293.1 - 5.1e-68 229.9 0.0 6.1e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YbjN PF10722.9 EGG22293.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator RsmF_methylt_CI PF17126.5 EGG22293.1 - 0.059 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 RsmF rRNA methyltransferase first C-terminal domain FeoB_C PF07664.12 EGG22293.1 - 0.13 11.9 0.9 3.9 7.2 0.3 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus MtrF PF09472.10 EGG22293.1 - 2.9 7.3 5.1 12 5.4 0.0 2.9 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Ank_2 PF12796.7 EGG22294.1 - 7.4e-48 161.1 13.2 2.7e-09 37.5 0.2 7.5 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22294.1 - 5.4e-42 141.6 3.2 4.9e-05 23.8 0.0 9.7 5 3 6 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22294.1 - 2.2e-35 120.2 12.1 0.015 15.6 0.1 13.2 3 2 11 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22294.1 - 3e-31 103.9 2.5 0.68 10.7 0.0 15.1 15 1 1 16 16 16 6 Ankyrin repeat DUF5049 PF16468.5 EGG22294.1 - 8e-15 54.5 8.3 0.87 9.5 0.0 10.7 4 4 8 12 12 12 5 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22294.1 - 1.1e-08 35.1 1.4 21 5.8 0.1 10.2 4 3 5 9 9 9 2 Ankyrin repeat Baculo_19 PF04798.12 EGG22294.1 - 0.19 11.5 1.0 16 5.2 0.1 3.9 3 1 0 4 4 4 0 Baculovirus 19 kDa protein conserved region DUF3430 PF11912.8 EGG22295.1 - 0.00073 19.6 7.4 0.00073 19.6 7.4 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3430) HSD3 PF15244.6 EGG22295.1 - 0.019 14.5 1.5 0.039 13.5 1.5 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Ank_2 PF12796.7 EGG22296.1 - 2.2e-07 31.4 0.0 5.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22296.1 - 3.3e-06 27.3 0.0 0.065 13.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22296.1 - 6.4e-06 26.6 0.2 0.0011 19.5 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22296.1 - 0.00066 19.9 0.1 2.9 8.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EGG22297.1 - 2.5e-12 47.2 6.7 1.4e-05 25.6 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22297.1 - 2.9e-09 37.3 0.6 0.089 13.4 0.0 4.9 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22297.1 - 4.1e-08 33.3 0.2 0.12 12.7 0.0 4.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22297.1 - 3.2e-05 24.0 1.2 15 6.6 0.0 6.2 7 0 0 7 7 7 2 Ankyrin repeat DUF5049 PF16468.5 EGG22297.1 - 0.0045 16.8 0.1 8.1 6.4 0.0 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF5049) Ank_2 PF12796.7 EGG22298.1 - 1.4e-30 105.7 9.4 1.2e-08 35.4 0.5 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22298.1 - 2.2e-19 69.2 1.6 9.8e-06 25.8 0.1 7.2 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22298.1 - 1.2e-17 64.0 2.1 0.0004 20.9 0.0 5.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22298.1 - 1.3e-16 59.0 0.2 0.14 12.8 0.0 8.1 8 0 0 8 8 8 4 Ankyrin repeat DUF5049 PF16468.5 EGG22298.1 - 1.5e-10 40.8 1.5 1.4 8.8 0.0 6.3 2 1 4 6 6 6 3 Domain of unknown function (DUF5049) DUF5071 PF16804.5 EGG22298.1 - 0.00091 19.5 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5071) Ank PF00023.30 EGG22298.1 - 0.0024 18.2 0.0 46 4.7 0.0 5.8 4 1 2 6 6 6 0 Ankyrin repeat NPC1_N PF16414.5 EGG22298.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus Ndc80_HEC PF03801.13 EGG22298.1 - 0.13 11.9 0.3 1.7 8.2 0.0 2.8 4 0 0 4 4 4 0 HEC/Ndc80p family RhoGAP PF00620.27 EGG22299.1 - 1.3e-27 96.5 0.1 2.4e-27 95.6 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain Motile_Sperm PF00635.26 EGG22299.1 - 0.0087 15.9 0.6 0.037 13.9 0.6 1.9 2 0 0 2 2 2 1 MSP (Major sperm protein) domain SPRY PF00622.28 EGG22300.1 - 6.6e-15 55.3 0.3 1.5e-14 54.1 0.1 1.7 2 0 0 2 2 2 1 SPRY domain F-box-like PF12937.7 EGG22300.1 - 3.3e-05 23.7 0.1 6.1e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EGG22300.1 - 0.0011 18.8 0.0 0.0029 17.5 0.0 1.7 1 0 0 1 1 1 1 F-box Neuralized PF07177.12 EGG22300.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Neuralized FAM60A PF15396.6 EGG22300.1 - 0.025 14.6 2.6 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein Family FAM60A PB1 PF00564.24 EGG22301.1 - 0.0071 16.3 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 PB1 domain APH_6_hur PF04655.14 EGG22301.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase UN_NPL4 PF11543.8 EGG22301.1 - 0.15 12.6 0.3 0.46 11.0 0.0 1.9 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Ank_2 PF12796.7 EGG22302.1 - 6.1e-22 78.0 7.8 1.6e-10 41.4 0.2 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG22302.1 - 2.8e-10 39.5 0.2 0.053 14.1 0.0 5.5 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 EGG22302.1 - 5.2e-10 39.7 0.0 0.00037 21.0 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22302.1 - 1.6e-07 31.5 0.1 0.2 12.0 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF5049 PF16468.5 EGG22302.1 - 1.2e-06 28.3 3.2 0.39 10.6 0.1 3.5 2 1 1 3 3 3 3 Domain of unknown function (DUF5049) BTHB PF18410.1 EGG22302.1 - 0.003 17.3 0.3 0.19 11.5 0.0 3.0 2 1 1 3 3 3 1 Basic tilted helix bundle domain Ank PF00023.30 EGG22302.1 - 0.021 15.2 0.0 27 5.4 0.0 4.2 2 1 0 2 2 2 0 Ankyrin repeat ORMDL PF04061.14 EGG22302.1 - 0.046 13.5 0.0 9.6 6.0 0.0 2.4 1 1 1 2 2 2 0 ORMDL family Ank_2 PF12796.7 EGG22303.1 - 1.6e-56 188.8 23.4 2.3e-12 47.3 0.5 7.7 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22303.1 - 7.6e-44 147.6 10.0 5.1e-07 30.1 0.0 10.0 9 1 2 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22303.1 - 7.5e-35 118.5 15.8 0.0024 18.1 0.1 13.0 4 4 10 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22303.1 - 7.3e-28 93.5 12.4 0.35 11.6 0.0 14.6 15 1 1 16 16 16 7 Ankyrin repeat Ank PF00023.30 EGG22303.1 - 1.8e-11 44.0 7.3 11 6.7 0.2 12.4 7 2 5 12 12 12 2 Ankyrin repeat DUF5049 PF16468.5 EGG22303.1 - 1.6e-10 40.7 3.2 8.9 6.3 0.0 9.0 5 2 5 10 10 10 4 Domain of unknown function (DUF5049) FaeA PF04703.12 EGG22303.1 - 0.1 13.0 0.1 0.66 10.4 0.1 2.5 2 0 0 2 2 2 0 FaeA-like protein Ank_2 PF12796.7 EGG22304.1 - 2.1e-53 178.9 12.0 1.9e-12 47.6 0.8 8.3 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22304.1 - 1.8e-44 149.5 8.3 1.4e-05 25.5 0.0 11.0 8 3 3 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22304.1 - 4.8e-39 131.9 13.3 0.00051 20.3 0.0 14.5 4 4 11 15 15 15 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22304.1 - 5.7e-30 100.0 7.0 0.013 16.0 0.0 14.6 15 1 1 16 16 16 7 Ankyrin repeat Ank PF00023.30 EGG22304.1 - 1.1e-11 44.6 6.7 1.1 9.9 0.0 11.4 7 4 4 11 11 11 2 Ankyrin repeat DUF5049 PF16468.5 EGG22304.1 - 1.3e-09 37.8 7.4 0.92 9.4 0.0 9.1 5 3 5 10 10 10 3 Domain of unknown function (DUF5049) DUF3447 PF11929.8 EGG22304.1 - 0.0012 18.7 7.3 1.3 9.0 0.1 6.0 3 2 2 6 6 6 2 Domain of unknown function (DUF3447) PrgU PF09627.10 EGG22304.1 - 0.035 14.1 0.8 0.095 12.7 0.8 1.8 1 0 0 1 1 1 0 PrgU-like protein AXE1 PF05448.12 EGG22304.1 - 0.06 12.0 0.1 0.65 8.6 0.0 2.7 3 1 0 3 3 3 0 Acetyl xylan esterase (AXE1) Peptidase_C48 PF02902.19 EGG22305.1 - 2.8e-07 30.6 0.1 4.4e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Hanta_nucleocap PF00846.18 EGG22306.1 - 0.14 10.6 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein LRR_6 PF13516.6 EGG22307.1 - 0.0027 17.6 2.1 0.08 13.0 0.4 2.4 2 0 0 2 2 2 2 Leucine Rich repeat ACBP PF00887.19 EGG22308.1 - 1.1e-24 86.5 0.1 2.1e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.6 EGG22308.1 - 8.7e-21 74.0 0.9 1.9e-14 53.8 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG22308.1 - 1.7e-20 73.4 1.3 2.3e-14 53.7 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG22308.1 - 3.3e-13 48.5 0.8 7.3e-05 22.9 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EGG22308.1 - 8.3e-13 48.2 0.2 1.6e-05 25.1 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EGG22308.1 - 1.6e-12 47.4 0.1 2.3e-08 34.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) CAP_GLY PF01302.25 EGG22309.1 - 3.4e-19 68.6 0.0 6.6e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EGG22309.1 - 1.7e-15 57.3 0.4 3.1e-15 56.4 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain SUIM_assoc PF16619.5 EGG22309.1 - 0.43 10.7 5.4 0.79 9.8 5.4 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Fez1 PF06818.15 EGG22310.1 - 0.00042 20.8 4.9 0.00042 20.8 4.9 3.2 1 1 2 3 3 3 1 Fez1 CENP-F_N PF10481.9 EGG22310.1 - 0.0013 18.4 9.9 0.0013 18.4 9.9 3.2 1 1 1 2 2 2 1 Cenp-F N-terminal domain CENP-Q PF13094.6 EGG22310.1 - 0.007 16.6 6.5 0.007 16.6 6.5 2.6 1 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Hamartin PF04388.12 EGG22310.1 - 0.22 10.2 29.3 0.32 9.6 29.3 1.2 1 0 0 1 1 1 0 Hamartin protein DUF3450 PF11932.8 EGG22310.1 - 0.74 9.1 44.0 0.0091 15.3 24.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.7 EGG22310.1 - 6.5 6.9 48.8 0.54 10.4 6.9 3.5 1 1 2 3 3 3 0 Tropomyosin like DUF3169 PF11368.8 EGG22311.1 - 0.015 14.8 0.7 0.023 14.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Tetraspanin PF00335.20 EGG22311.1 - 0.023 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF2427 PF10348.9 EGG22311.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF4064 PF13273.6 EGG22311.1 - 0.42 10.9 3.8 0.33 11.2 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) FTSW_RODA_SPOVE PF01098.19 EGG22311.1 - 1.8 7.4 5.9 2.6 7.0 5.9 1.1 1 0 0 1 1 1 0 Cell cycle protein PalH PF08733.10 EGG22311.1 - 3.5 6.6 9.3 3.8 6.4 7.7 1.7 1 1 1 2 2 2 0 PalH/RIM21 GWT1 PF06423.12 EGG22312.1 - 1.5e-31 109.6 8.9 1.5e-31 109.6 8.9 3.4 2 1 1 3 3 3 1 GWT1 CrgA PF06781.12 EGG22312.1 - 0.0023 18.0 0.1 0.0023 18.0 0.1 3.3 2 2 2 4 4 4 1 Cell division protein CrgA TRAM1 PF08390.11 EGG22312.1 - 0.2 11.3 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 TRAM1-like protein Metallophos PF00149.28 EGG22315.1 - 2e-21 77.4 2.2 3.1e-21 76.8 1.4 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EGG22315.1 - 1.3e-18 67.6 0.7 3.2e-18 66.3 0.1 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EGG22315.1 - 1.1e-15 57.9 1.3 1.1e-15 57.9 1.3 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 EGG22315.1 - 0.00054 20.2 0.0 0.00092 19.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.7 EGG22316.1 - 1.5e-20 73.5 0.2 2.6e-12 47.1 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22316.1 - 1.1e-18 67.0 0.1 0.0015 18.8 0.0 5.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22316.1 - 8.2e-17 61.4 0.1 4.9e-07 30.2 0.1 4.2 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22316.1 - 8.2e-11 41.2 0.0 0.8 10.5 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat DUF5049 PF16468.5 EGG22316.1 - 4.2e-05 23.4 0.0 3.7 7.5 0.0 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF5049) Nucleopor_Nup85 PF07575.13 EGG22316.1 - 0.0011 17.7 0.5 0.079 11.5 0.1 2.6 3 0 0 3 3 3 2 Nup85 Nucleoporin Ank PF00023.30 EGG22316.1 - 0.018 15.5 1.4 36 5.0 0.1 4.7 4 1 1 5 5 5 0 Ankyrin repeat Ank_2 PF12796.7 EGG22317.1 - 2e-81 268.6 28.4 3.8e-10 40.2 0.0 10.2 3 2 10 13 13 13 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22317.1 - 2e-52 174.9 7.2 5.6e-06 26.8 0.0 12.3 11 2 1 12 12 12 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22317.1 - 4.8e-44 147.8 17.8 0.00067 19.9 0.0 17.9 5 2 11 18 18 18 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22317.1 - 4.3e-37 121.9 13.7 1.7 9.4 0.0 21.6 20 3 3 23 23 23 7 Ankyrin repeat DUF5049 PF16468.5 EGG22317.1 - 1.2e-21 76.4 17.9 0.65 9.9 0.0 14.6 7 4 8 15 15 15 6 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22317.1 - 9.7e-14 51.1 6.7 1.8 9.2 0.0 13.6 6 4 4 10 10 10 1 Ankyrin repeat Insulin PF00049.18 EGG22317.1 - 0.00043 21.2 4.3 1.7 9.7 0.2 4.0 3 2 0 3 3 3 2 Insulin/IGF/Relaxin family Nup188 PF10487.9 EGG22317.1 - 0.00077 17.5 5.1 0.0081 14.1 0.3 2.9 3 0 0 3 3 3 1 Nucleoporin subcomplex protein binding to Pom34 Ank_2 PF12796.7 EGG22318.1 - 3.4e-65 216.6 19.9 2e-10 41.1 0.0 7.9 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22318.1 - 2.1e-47 158.9 1.6 8.9e-07 29.4 0.0 9.6 6 2 5 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22318.1 - 2.5e-39 132.8 6.7 0.031 14.6 0.0 14.0 4 3 10 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22318.1 - 2.3e-33 110.4 2.0 1.1 10.0 0.0 15.7 16 1 1 17 17 17 10 Ankyrin repeat DUF5049 PF16468.5 EGG22318.1 - 8.4e-18 64.0 19.7 0.7 9.8 0.1 12.8 5 4 9 14 14 14 6 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22318.1 - 1.2e-09 38.2 6.8 7.3 7.2 0.0 11.6 9 4 4 13 13 13 1 Ankyrin repeat Vps23_core PF09454.10 EGG22318.1 - 0.0023 17.8 1.0 18 5.4 0.0 6.3 6 3 3 9 9 9 1 Vps23 core domain BMC PF00936.19 EGG22318.1 - 0.067 13.2 7.3 15 5.7 0.0 6.0 5 4 2 7 7 7 0 BMC domain Ank_2 PF12796.7 EGG22319.1 - 8.2e-48 160.9 9.3 2.8e-09 37.4 0.0 7.6 1 1 8 9 9 9 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22319.1 - 1.6e-36 123.9 7.4 0.0026 18.0 0.1 13.9 3 3 11 14 14 14 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22319.1 - 3.4e-36 123.1 10.5 1.2e-06 28.9 0.0 11.1 3 2 8 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22319.1 - 1.5e-28 95.7 1.6 0.11 13.1 0.0 14.9 13 2 2 15 15 15 5 Ankyrin repeat DUF5049 PF16468.5 EGG22319.1 - 1.4e-15 56.9 12.2 0.65 9.9 0.0 11.6 4 2 8 12 12 12 4 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22319.1 - 3.5e-10 39.9 0.1 11 6.6 0.0 10.5 5 3 3 8 8 8 2 Ankyrin repeat Ank_2 PF12796.7 EGG22320.1 - 2.7e-56 188.1 16.2 2e-11 44.3 0.0 7.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22320.1 - 3.5e-41 139.1 7.3 1.3e-05 25.6 0.0 10.5 7 3 5 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22320.1 - 3.1e-36 122.9 9.5 0.13 12.6 0.0 14.6 2 1 13 15 15 15 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22320.1 - 1.2e-31 105.2 0.3 1.7 9.5 0.0 15.1 14 1 1 15 15 15 7 Ankyrin repeat DUF5049 PF16468.5 EGG22320.1 - 9.5e-15 54.2 9.8 1.7 8.6 0.0 12.5 5 3 8 13 13 13 4 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22320.1 - 2.4e-12 46.7 0.3 37 5.0 0.0 12.1 5 1 3 8 8 8 0 Ankyrin repeat FAM195 PF14799.6 EGG22320.1 - 0.018 15.4 2.6 42 4.6 0.2 6.1 4 2 3 8 8 8 0 FAM195 family UTP15_C PF09384.10 EGG22320.1 - 0.025 14.3 0.0 4.9 6.8 0.0 3.3 3 0 0 3 3 3 0 UTP15 C terminal DUF5099 PF17025.5 EGG22320.1 - 0.063 13.7 0.0 64 4.0 0.0 4.3 3 1 1 5 5 5 0 Domain of unknown function (DUF5099) Ank_2 PF12796.7 EGG22321.1 - 3.3e-72 239.1 25.7 1.5e-10 41.5 0.1 11.9 3 2 12 15 15 15 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22321.1 - 3.8e-61 202.7 15.0 1.5e-06 28.6 0.0 15.3 13 4 1 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22321.1 - 6.5e-42 136.7 7.0 1.6 9.5 0.0 22.3 22 2 2 24 24 24 9 Ankyrin repeat Ank_5 PF13857.6 EGG22321.1 - 9.1e-41 137.4 19.8 0.043 14.1 0.1 19.3 7 4 14 21 21 21 13 Ankyrin repeats (many copies) DUF5049 PF16468.5 EGG22321.1 - 3.3e-23 81.3 18.1 1.5 8.8 0.0 15.8 8 3 9 17 17 17 8 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22321.1 - 1.2e-11 44.5 9.8 14 6.3 0.1 14.7 9 4 5 14 14 14 1 Ankyrin repeat Vps23_core PF09454.10 EGG22321.1 - 8.1e-06 25.7 0.8 33 4.5 0.0 8.3 7 3 4 11 11 11 0 Vps23 core domain DUF3042 PF11240.8 EGG22321.1 - 5.2 7.2 5.7 14 5.7 5.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) EGF_2 PF07974.13 EGG22322.1 - 2.5e-07 30.9 30.6 0.00057 20.2 14.4 3.0 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGG22322.1 - 0.011 15.8 23.4 0.047 13.8 3.4 2.8 2 0 0 2 2 2 0 Tenascin EGF domain EB PF01683.18 EGG22322.1 - 0.43 10.9 15.6 0.62 10.4 3.3 2.7 2 0 0 2 2 2 0 EB module hEGF PF12661.7 EGG22322.1 - 3.5 8.4 27.6 1.6 9.4 7.5 3.5 3 0 0 3 3 3 0 Human growth factor-like EGF Ala_racemase_C PF00842.21 EGG22323.1 - 0.022 14.6 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain Ependymin PF00811.18 EGG22324.1 - 0.028 14.7 4.5 0.28 11.5 0.7 2.4 1 1 1 2 2 2 0 Ependymin Rxt3 PF08642.10 EGG22325.1 - 0.0078 17.0 1.9 0.0078 17.0 1.9 2.2 2 1 1 3 3 3 1 Histone deacetylation protein Rxt3 Nkap_C PF06047.11 EGG22325.1 - 0.16 12.1 3.1 0.31 11.2 3.1 1.4 1 0 0 1 1 1 0 NF-kappa-B-activating protein C-terminal domain ATP-synt_G PF04718.15 EGG22326.1 - 2.8e-05 24.9 0.1 3.2e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DUF3254 PF11630.8 EGG22326.1 - 0.14 12.4 0.2 0.21 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) DUF1899 PF08953.11 EGG22328.1 - 2.7e-32 110.4 0.4 5.7e-32 109.4 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EGG22328.1 - 6.7e-18 64.3 0.1 1.2e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EGG22328.1 - 8.1e-15 55.0 1.7 0.00031 21.5 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG22328.1 - 0.0022 18.3 0.4 0.22 11.8 0.1 3.7 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG22328.1 - 0.0042 17.0 0.4 0.066 13.1 0.1 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Sacchrp_dh_NADP PF03435.18 EGG22328.1 - 0.056 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1031 PF06275.11 EGG22329.1 - 0.083 13.1 0.4 4.8 7.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) PH_15 PF17339.2 EGG22330.1 - 0.019 14.8 0.0 12 5.8 0.0 3.5 3 0 0 3 3 3 0 PH domain DUF3452 PF11934.8 EGG22330.1 - 0.036 13.6 2.8 0.066 12.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) DUF4667 PF15700.5 EGG22334.1 - 0.054 13.6 12.0 0.069 13.2 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) DUF2115 PF09888.9 EGG22334.1 - 0.63 10.5 9.6 0.074 13.6 1.6 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF4407 PF14362.6 EGG22334.1 - 0.63 9.3 3.6 0.48 9.7 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Enkurin PF13864.6 EGG22334.1 - 8.9 6.8 11.1 51 4.4 0.2 2.1 1 1 1 2 2 2 0 Calmodulin-binding PRP3 PF08572.10 EGG22335.1 - 9e-43 146.6 12.1 9e-43 146.6 12.1 2.4 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EGG22335.1 - 5.5e-37 127.1 0.0 5.5e-37 127.1 0.0 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF1115) Aldo_ket_red PF00248.21 EGG22337.1 - 3.5e-47 161.0 0.0 4.3e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SWI-SNF_Ssr4 PF08549.10 EGG22338.1 - 0.081 11.6 8.4 0.079 11.6 8.4 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Prp18 PF02840.15 EGG22339.1 - 1.2e-60 203.7 0.9 1.2e-60 203.7 0.9 2.7 3 1 0 3 3 3 1 Prp18 domain PRP4 PF08799.11 EGG22339.1 - 6.8e-13 47.9 1.7 1.3e-12 47.0 1.7 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like PTPA PF03095.15 EGG22339.1 - 0.023 14.2 0.1 0.047 13.1 0.1 1.5 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein DUF2470 PF10615.9 EGG22340.1 - 1.2e-08 35.5 0.0 2.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pyrid_oxidase_2 PF13883.6 EGG22340.1 - 7.6e-07 29.2 1.1 1.4e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase SR-25 PF10500.9 EGG22340.1 - 0.14 11.8 4.4 0.21 11.2 4.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Vps52 PF04129.12 EGG22341.1 - 2.1e-64 218.2 26.2 2.3e-63 214.7 23.8 2.8 2 1 0 2 2 2 1 Vps52 / Sac2 family Sec3_C PF09763.9 EGG22341.1 - 2.5e-09 36.1 28.3 3.3e-05 22.5 1.4 3.1 1 1 1 2 2 2 2 Exocyst complex component Sec3 GST_N_4 PF17172.4 EGG22341.1 - 0.021 15.6 0.1 1.2 10.0 0.0 2.9 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Med4 PF10018.9 EGG22341.1 - 0.18 11.4 3.2 0.62 9.7 0.2 2.7 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 F-box-like PF12937.7 EGG22342.1 - 0.0021 17.9 0.1 0.0039 17.0 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG22342.1 - 0.003 17.4 0.3 0.0085 15.9 0.3 1.8 1 0 0 1 1 1 1 F-box domain DUF440 PF04269.12 EGG22342.1 - 0.082 13.2 0.0 0.28 11.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF440 RhoGEF PF00621.20 EGG22344.1 - 2.8e-37 128.7 15.5 7.8e-37 127.3 5.8 3.5 2 1 0 2 2 2 2 RhoGEF domain PEPCK_ATP PF01293.20 EGG22345.1 - 2.3e-153 511.3 0.0 1.2e-102 344.0 0.0 2.0 1 1 1 2 2 2 2 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 EGG22345.1 - 0.068 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PH PF00169.29 EGG22348.1 - 6.9e-23 81.2 11.4 1.9e-15 57.3 0.6 4.2 2 1 1 3 3 3 3 PH domain PH_6 PF15406.6 EGG22348.1 - 1.8e-06 28.2 3.6 2.7e-06 27.7 0.0 3.0 2 1 1 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.6 EGG22348.1 - 3.8e-06 27.3 26.7 0.00027 21.3 1.1 5.7 5 1 0 5 5 5 3 Pleckstrin homology domain PH_3 PF14593.6 EGG22348.1 - 5.9e-06 26.3 4.5 0.0034 17.5 0.2 3.4 2 1 1 3 3 3 2 PH domain PH_9 PF15410.6 EGG22348.1 - 0.0084 16.5 3.3 0.0084 16.5 3.3 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain DUF2052 PF09747.9 EGG22348.1 - 0.13 12.3 13.8 0.15 12.2 7.8 2.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.17 EGG22348.1 - 5.9 7.0 15.5 0.091 12.9 1.6 3.2 2 1 0 2 2 2 0 DDHD domain Rap_GAP PF02145.15 EGG22349.1 - 5.4e-59 198.9 0.5 1.5e-58 197.4 0.0 1.9 2 1 0 2 2 2 1 Rap/ran-GAP DUF3244 PF11589.8 EGG22349.1 - 0.056 13.5 0.2 0.13 12.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) rve PF00665.26 EGG22350.1 - 1.1e-11 45.0 0.0 1.5e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EGG22350.1 - 0.003 17.3 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Cse1 PF08506.10 EGG22350.1 - 0.025 13.4 0.0 0.028 13.2 0.0 1.0 1 0 0 1 1 1 0 Cse1 GHD PF17834.1 EGG22351.1 - 0.18 11.9 1.3 0.23 11.5 1.3 1.2 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase LisH PF08513.11 EGG22352.1 - 0.084 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 LisH DUF2203 PF09969.9 EGG22353.1 - 0.69 10.6 6.2 0.76 10.5 3.7 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1178 PF06676.11 EGG22353.1 - 1.8 8.9 10.8 0.064 13.7 2.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) FHIPEP PF00771.20 EGG22353.1 - 3.7 5.9 5.9 6.7 5.0 5.9 1.4 1 0 0 1 1 1 0 FHIPEP family tRNA-synt_1b PF00579.25 EGG22354.1 - 6.8e-20 71.6 0.1 2.3e-19 69.8 0.0 1.9 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) Lys-AminoMut_A PF09043.11 EGG22354.1 - 0.036 12.5 0.1 0.051 12.0 0.1 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit GTP_EFTU PF00009.27 EGG22355.1 - 1.1e-55 188.2 0.0 1.9e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGG22355.1 - 2.4e-38 130.9 0.2 1.3e-37 128.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGG22355.1 - 2.5e-16 59.8 0.1 7e-16 58.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGG22355.1 - 0.00013 22.0 0.0 0.0028 17.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EGG22355.1 - 0.00048 20.0 2.8 0.00071 19.4 0.1 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 4 NIF3 PF01784.18 EGG22355.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) FlpD PF02662.16 EGG22355.1 - 0.081 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Gtr1_RagA PF04670.12 EGG22355.1 - 0.16 11.3 0.0 0.36 10.1 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_60s PF00428.19 EGG22357.1 - 0.0052 17.3 4.4 0.0082 16.7 4.4 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein FAM176 PF14851.6 EGG22357.1 - 0.083 12.6 3.3 0.11 12.1 3.3 1.2 1 0 0 1 1 1 0 FAM176 family HcyBio PF01837.16 EGG22357.1 - 0.087 11.7 0.0 0.22 10.4 0.0 1.6 1 1 1 2 2 2 0 Homocysteine biosynthesis enzyme, sulfur-incorporation DUF3446 PF11928.8 EGG22358.1 - 0.018 15.4 16.4 0.33 11.3 0.4 4.6 4 0 0 4 4 4 0 Early growth response N-terminal domain DUF3310 PF11753.8 EGG22358.1 - 0.056 13.6 0.4 18 5.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknwon function (DUF3310) TerY_C PF15616.6 EGG22358.1 - 0.73 10.0 10.9 0.19 11.8 4.9 3.1 3 0 0 3 3 3 0 TerY-C metal binding domain zf-CW PF07496.15 EGG22358.1 - 2.6 8.2 6.2 0.72 9.9 0.1 3.0 3 0 0 3 3 3 0 CW-type Zinc Finger DUF5069 PF16798.5 EGG22359.1 - 0.13 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) Peptidase_M9 PF01752.17 EGG22360.1 - 0.056 12.7 2.2 0.072 12.3 2.2 1.1 1 0 0 1 1 1 0 Collagenase Involucrin2 PF06994.11 EGG22360.1 - 1.8 8.7 5.8 5.5 7.2 0.1 2.4 2 0 0 2 2 2 0 Involucrin NDUF_B7 PF05676.13 EGG22361.1 - 2e-30 104.3 3.2 2.5e-30 104.0 3.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EGG22361.1 - 0.0045 17.0 2.2 0.0065 16.5 2.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Band_7 PF01145.25 EGG22362.1 - 1.1e-25 90.7 1.0 1.9e-25 89.9 1.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EGG22362.1 - 0.0064 15.6 0.8 0.008 15.3 0.8 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial SH3_1 PF00018.28 EGG22363.1 - 3.5e-23 80.9 3.4 3.7e-15 55.2 0.1 2.8 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 EGG22363.1 - 9.9e-18 63.8 0.2 4.4e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 EGG22363.1 - 2.1e-17 62.5 0.6 2.9e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 EGG22363.1 - 4.3e-11 42.9 0.1 4.3e-11 42.9 0.1 3.0 3 1 1 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.6 EGG22363.1 - 0.093 12.1 8.5 0.14 11.5 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DIT1_PvcA PF05141.12 EGG22363.1 - 0.51 9.7 7.2 1.1 8.7 7.2 1.6 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Nup88 PF10168.9 EGG22363.1 - 0.67 7.7 14.5 0.97 7.2 14.5 1.2 1 0 0 1 1 1 0 Nuclear pore component TPR_MLP1_2 PF07926.12 EGG22363.1 - 3.1 7.9 20.0 1.7 8.7 12.1 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4771 PF15995.5 EGG22363.1 - 3.7 7.8 11.2 3.6 7.8 5.4 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4771) SLX9 PF15341.6 EGG22363.1 - 3.7 7.9 16.5 1.1 9.7 13.0 2.0 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 FRB_dom PF08771.11 EGG22363.1 - 3.9 8.0 6.8 3.8 8.0 4.3 2.3 2 1 0 2 2 1 0 FKBP12-rapamycin binding domain Big_2 PF02368.18 EGG22364.1 - 3.8e-14 52.3 0.2 0.0098 15.8 0.0 7.1 6 0 0 6 6 6 4 Bacterial Ig-like domain (group 2) BiPBP_C PF06832.12 EGG22364.1 - 6.9e-05 22.8 0.0 0.024 14.7 0.0 3.4 3 0 0 3 3 3 2 Penicillin-Binding Protein C-terminus Family T2SS-T3SS_pil_N PF13629.6 EGG22364.1 - 0.0048 16.6 6.6 3.9 7.3 0.0 6.3 6 0 0 6 6 6 1 Pilus formation protein N terminal region ADP_ribosyl_GH PF03747.14 EGG22365.1 - 4.8e-48 164.4 0.0 5.5e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase GST_C_3 PF14497.6 EGG22366.1 - 3.7e-20 72.0 0.0 6.4e-20 71.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGG22366.1 - 4.4e-08 33.4 0.0 8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG22366.1 - 0.00013 22.1 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG22366.1 - 0.0021 18.0 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGG22366.1 - 0.0072 16.1 0.2 0.021 14.6 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGG22366.1 - 0.024 15.0 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EGG22366.1 - 0.13 13.0 0.0 0.23 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain eIF3_subunit PF08597.10 EGG22367.1 - 3.2e-46 158.2 20.1 3.5e-46 158.1 20.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF3533 PF12051.8 EGG22367.1 - 0.24 10.3 1.4 0.3 9.9 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) HLH PF00010.26 EGG22367.1 - 2.3 8.2 4.5 0.71 9.9 0.9 1.9 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain ETF_QO PF05187.13 EGG22368.1 - 0.038 14.1 0.3 0.073 13.2 0.3 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Kunitz_BPTI PF00014.23 EGG22368.1 - 0.4 11.0 5.5 0.11 12.8 1.8 2.0 2 0 0 2 2 2 0 Kunitz/Bovine pancreatic trypsin inhibitor domain CBM_14 PF01607.24 EGG22368.1 - 0.8 9.9 5.4 0.19 11.9 1.0 2.1 2 1 0 2 2 2 0 Chitin binding Peritrophin-A domain Usp PF00582.26 EGG22369.1 - 1.7e-21 77.2 0.1 2.2e-21 76.9 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family NOGCT PF08155.11 EGG22369.1 - 0.087 12.8 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 NOGCT (NUC087) domain LETM1 PF07766.13 EGG22370.1 - 1.1e-84 283.9 7.0 1.1e-84 283.9 7.0 2.4 3 0 0 3 3 3 1 LETM1-like protein Pex19 PF04614.12 EGG22370.1 - 3.6e-05 23.7 8.9 3.6e-05 23.7 8.9 4.6 2 1 0 3 3 3 1 Pex19 protein family CDH1_2_SANT_HL1 PF18375.1 EGG22370.1 - 8 7.2 11.5 69 4.2 0.2 3.3 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Fcf1 PF04900.12 EGG22371.1 - 5.8e-33 113.2 0.8 1.2e-32 112.2 0.8 1.6 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EGG22371.1 - 2.3e-08 34.3 0.0 3.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 PIN like domain Peptidase_M20 PF01546.28 EGG22372.1 - 2.4e-31 109.1 0.0 3.2e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGG22372.1 - 3.1e-13 49.6 0.0 7.3e-13 48.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGG22372.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 VPS9 PF02204.18 EGG22373.1 - 8.8e-28 96.6 0.6 2.2e-27 95.3 0.4 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain FluMu_N PF17891.1 EGG22374.1 - 0.054 13.3 0.0 0.058 13.2 0.0 1.1 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain TFIIA PF03153.13 EGG22375.1 - 0.00063 19.9 109.3 0.022 14.7 30.2 4.4 4 0 0 4 4 4 3 Transcription factor IIA, alpha/beta subunit RasGEF PF00617.19 EGG22376.1 - 2.6e-15 57.1 0.0 4.9e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain ADH_N PF08240.12 EGG22378.1 - 2.3e-28 98.3 5.5 5e-28 97.2 5.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGG22378.1 - 1.4e-20 73.6 0.0 2.3e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGG22378.1 - 0.00014 21.5 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGG22378.1 - 0.0013 19.8 0.0 0.0027 18.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zip PF02535.22 EGG22379.1 - 3.7e-52 177.6 3.5 2.4e-51 174.9 3.5 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter zf-CCHC PF00098.23 EGG22380.1 - 3.3e-08 33.2 21.7 0.0029 17.6 2.1 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 EGG22380.1 - 0.017 15.1 21.9 0.034 14.1 1.7 4.3 3 1 1 4 4 4 0 Zinc knuckle p450 PF00067.22 EGG22381.1 - 7.8e-103 344.7 0.0 1.1e-102 344.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UCR_hinge PF02320.16 EGG22381.1 - 2.6e-09 37.1 4.2 4.8e-09 36.3 4.2 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Myb_DNA-binding PF00249.31 EGG22382.1 - 1.6e-11 44.2 0.0 2.8e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Dickkopf_N PF04706.12 EGG22383.1 - 1.7e-05 25.2 39.4 0.00079 19.8 8.7 4.2 2 2 2 4 4 4 3 Dickkopf N-terminal cysteine-rich region EB PF01683.18 EGG22383.1 - 6.6 7.1 42.1 2.6 8.4 8.6 4.8 1 1 2 3 3 3 0 EB module Sec34 PF04136.15 EGG22385.1 - 0.0023 17.8 2.2 0.0028 17.5 2.2 1.2 1 0 0 1 1 1 1 Sec34-like family ZapD PF07072.11 EGG22385.1 - 0.01 15.6 2.3 0.011 15.6 2.3 1.1 1 0 0 1 1 1 0 Cell division protein SAS4 PF15460.6 EGG22385.1 - 0.041 14.0 2.5 0.048 13.8 2.5 1.2 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Phage_int_SAM_6 PF18644.1 EGG22385.1 - 0.047 13.7 1.2 0.056 13.5 1.2 1.3 1 0 0 1 1 1 0 Phage integrase SAM-like domain YabA PF06156.13 EGG22385.1 - 0.067 13.8 3.6 0.097 13.3 3.6 1.3 1 0 0 1 1 1 0 Initiation control protein YabA V_ATPase_I PF01496.19 EGG22385.1 - 0.087 10.7 3.2 0.085 10.8 3.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HicB_lk_antitox PF15919.5 EGG22385.1 - 0.095 12.8 0.5 0.14 12.3 0.4 1.3 1 1 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Wbp11 PF09429.10 EGG22385.1 - 0.15 12.5 6.3 0.84 10.1 2.4 2.1 1 1 1 2 2 2 0 WW domain binding protein 11 TMPIT PF07851.13 EGG22385.1 - 0.23 10.7 2.4 0.25 10.5 2.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 EGG22385.1 - 0.24 11.4 5.8 0.24 11.4 5.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) PCRF PF03462.18 EGG22385.1 - 0.28 11.0 3.0 0.3 10.9 3.0 1.1 1 0 0 1 1 1 0 PCRF domain FlaC_arch PF05377.11 EGG22385.1 - 2.9 8.4 7.3 3.3 8.2 6.2 1.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) FNIP PF05725.12 EGG22386.1 - 7.3e-46 154.1 31.8 1.3e-11 44.4 0.4 9.9 8 2 3 11 11 11 8 FNIP Repeat SPX PF03105.19 EGG22386.1 - 0.067 13.1 5.3 0.17 11.7 5.3 1.5 1 1 0 1 1 1 0 SPX domain Rxt3 PF08642.10 EGG22386.1 - 5.2 7.9 7.9 1.5 9.6 1.3 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Phospholip_B PF04916.13 EGG22387.1 - 4.2e-162 540.4 14.8 5.1e-162 540.2 14.8 1.0 1 0 0 1 1 1 1 Phospholipase B DUF5590 PF17881.1 EGG22387.1 - 0.067 13.3 0.6 0.24 11.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5590) NTP_transf_9 PF04248.12 EGG22387.1 - 0.1 12.5 1.7 0.19 11.7 0.2 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF427) N1221 PF07923.13 EGG22388.1 - 0.0056 15.9 0.3 0.0086 15.3 0.3 1.2 1 0 0 1 1 1 1 N1221-like protein MAGE PF01454.19 EGG22388.1 - 0.076 12.7 0.5 0.12 12.0 0.5 1.3 1 0 0 1 1 1 0 MAGE family DASH_Dam1 PF08653.10 EGG22388.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Dam1 Med2 PF11214.8 EGG22388.1 - 1.4 9.2 6.0 0.95 9.6 4.1 1.7 2 0 0 2 2 2 0 Mediator complex subunit 2 Ank_4 PF13637.6 EGG22390.1 - 4.4e-25 87.7 8.9 6.9e-06 26.5 0.1 8.7 4 3 7 11 11 11 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG22390.1 - 3.6e-22 78.8 5.9 6.9e-05 23.4 0.1 6.3 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22390.1 - 1.5e-18 66.6 9.5 0.0063 16.8 0.1 9.4 3 2 7 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22390.1 - 1.7e-13 49.4 7.3 5.6 7.9 0.0 12.1 10 2 2 12 12 12 2 Ankyrin repeat Ank PF00023.30 EGG22390.1 - 0.0026 18.1 0.1 84 3.9 0.0 6.6 6 2 1 7 7 7 0 Ankyrin repeat DUF249 PF03158.13 EGG22390.1 - 0.036 13.8 4.1 0.47 10.1 0.3 3.9 3 1 0 4 4 4 0 Multigene family 530 protein Ank_5 PF13857.6 EGG22391.1 - 1.8e-27 95.0 10.1 0.00049 20.4 0.2 10.6 8 3 3 11 11 11 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG22391.1 - 4.4e-26 91.3 13.2 1.9e-05 25.2 0.1 6.6 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22391.1 - 5.9e-23 80.9 14.3 7e-07 29.7 0.1 8.1 6 3 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22391.1 - 7.1e-15 53.6 4.3 0.94 10.3 0.0 10.8 13 0 0 13 13 13 3 Ankyrin repeat Ank PF00023.30 EGG22391.1 - 0.00041 20.7 0.4 84 3.9 0.0 6.9 7 4 2 9 9 9 0 Ankyrin repeat Baculo_19 PF04798.12 EGG22391.1 - 0.024 14.4 1.1 18 5.0 0.0 3.7 2 1 1 3 3 3 0 Baculovirus 19 kDa protein conserved region ECH_1 PF00378.20 EGG22392.1 - 5.6e-42 143.8 0.0 1.3e-41 142.6 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGG22392.1 - 1.5e-18 67.4 1.5 1.2e-16 61.1 0.0 2.5 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase CS PF04969.16 EGG22393.1 - 1.5e-11 45.1 3.1 3e-11 44.2 3.1 1.5 1 0 0 1 1 1 1 CS domain Peptidase_M3 PF01432.20 EGG22394.1 - 3.4e-87 293.6 1.0 6e-87 292.8 1.0 1.4 1 0 0 1 1 1 1 Peptidase family M3 Ras PF00071.22 EGG22396.1 - 6.8e-34 116.8 0.0 8.7e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG22396.1 - 1e-22 80.6 0.0 2.1e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG22396.1 - 4.3e-11 42.6 0.0 5.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG22396.1 - 1.7e-05 24.9 0.2 6.9e-05 22.9 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG22396.1 - 0.00016 21.6 0.1 0.051 13.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGG22396.1 - 0.0021 17.4 2.8 0.0074 15.7 2.8 2.0 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EGG22396.1 - 0.014 15.7 0.7 0.26 11.6 0.7 2.3 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EGG22396.1 - 0.028 14.2 0.7 0.68 9.7 0.0 2.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EGG22396.1 - 0.039 14.5 0.6 0.066 13.7 0.6 1.7 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EGG22396.1 - 0.074 13.2 0.0 0.1 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 EGG22397.1 - 2.8e-29 101.8 0.0 3.2e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG22397.1 - 2.8e-11 43.7 0.0 4.7e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG22397.1 - 0.00078 18.9 0.0 0.00095 18.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF2052 PF09747.9 EGG22398.1 - 1.5e-16 61.1 31.5 1.5e-16 61.1 31.5 2.3 2 1 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.17 EGG22398.1 - 0.36 11.0 7.5 0.15 12.2 3.2 2.0 2 0 0 2 2 2 0 DDHD domain Cytomega_UL84 PF06284.11 EGG22398.1 - 0.56 8.6 6.3 0.78 8.1 6.3 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DNA_pol_phi PF04931.13 EGG22398.1 - 1.7 6.7 31.3 2.8 5.9 31.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi PBP_sp32 PF07222.12 EGG22398.1 - 2.8 7.3 9.4 4.8 6.6 9.4 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 MscS_TM PF12794.7 EGG22398.1 - 2.9 6.6 3.7 4.5 6.0 3.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 ALMT PF11744.8 EGG22398.1 - 4.1 6.1 6.4 5.7 5.6 6.4 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter CobT PF06213.12 EGG22398.1 - 7.6 5.8 18.0 14 4.9 18.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Trp_Tyr_perm PF03222.13 EGG22399.1 - 1.6e-05 24.1 0.3 1.6e-05 24.1 0.3 3.7 4 0 0 4 4 4 3 Tryptophan/tyrosine permease family IBR PF01485.21 EGG22401.1 - 1.2e-16 60.7 25.0 3e-10 40.2 7.0 4.6 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain CUE PF02845.16 EGG22401.1 - 1.3e-08 34.4 0.2 7.3e-08 32.0 0.3 2.4 2 0 0 2 2 2 1 CUE domain SPX PF03105.19 EGG22401.1 - 0.047 13.6 0.2 0.047 13.6 0.2 8.0 2 2 1 4 4 4 0 SPX domain DUF3605 PF12239.8 EGG22402.1 - 5.8e-24 85.2 8.4 5.8e-24 85.2 8.4 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3605) DDHD PF02862.17 EGG22403.1 - 2.6 8.2 7.9 4.6 7.3 7.9 1.4 1 0 0 1 1 1 0 DDHD domain Kelch_1 PF01344.25 EGG22404.1 - 1.9e-35 120.2 12.7 9.3e-08 31.5 0.0 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EGG22404.1 - 4.6e-30 103.4 6.1 4.9e-08 32.9 0.0 6.5 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EGG22404.1 - 9.9e-30 101.8 12.3 1.6e-06 28.2 0.1 6.7 2 1 4 6 6 6 5 Kelch motif Kelch_3 PF13415.6 EGG22404.1 - 1.6e-18 66.5 1.5 1.4e-05 25.2 0.1 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG22404.1 - 5.4e-12 45.4 15.7 0.054 13.5 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EGG22404.1 - 2.1e-10 40.1 2.7 0.0015 18.4 0.0 5.4 6 0 0 6 6 6 2 Kelch motif zf-C3HC4_2 PF13923.6 EGG22404.1 - 1.8e-06 27.7 2.5 1.8e-06 27.7 2.5 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG22404.1 - 1.2e-05 25.2 2.6 1.2e-05 25.2 2.6 2.4 2 0 0 2 2 1 1 RING-type zinc-finger zf-B_box PF00643.24 EGG22404.1 - 0.00013 22.1 11.6 0.00013 22.1 11.6 4.3 3 1 0 3 3 2 1 B-box zinc finger zf-C3HC4 PF00097.25 EGG22404.1 - 0.00013 21.7 7.3 0.00013 21.7 7.3 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGG22404.1 - 0.00026 21.1 8.9 0.00026 21.1 8.9 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGG22404.1 - 0.01 15.8 5.4 0.01 15.8 5.4 2.4 2 0 0 2 2 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 EGG22404.1 - 0.19 11.6 1.4 0.5 10.3 1.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein 7tm_3 PF00003.22 EGG22405.1 - 3.1e-45 154.7 28.5 4.6e-45 154.2 28.5 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 EGG22405.1 - 1e-41 143.3 0.0 1.6e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Ras PF00071.22 EGG22405.1 - 4.8e-33 114.1 0.0 7.5e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG22405.1 - 1.9e-23 82.9 0.0 3.6e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Peripla_BP_6 PF13458.6 EGG22405.1 - 7.8e-12 45.5 0.0 1.4e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Arf PF00025.21 EGG22405.1 - 3.7e-10 39.5 0.0 6.8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG22405.1 - 0.0002 21.4 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG22405.1 - 0.00025 20.7 0.0 0.00049 19.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EGG22405.1 - 0.0012 18.1 0.5 3.5 6.7 0.0 3.0 1 1 1 2 2 2 2 G-protein alpha subunit ATP_bind_1 PF03029.17 EGG22405.1 - 0.0014 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 EGG22405.1 - 0.0058 16.0 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Cadherin_4 PF17803.1 EGG22405.1 - 0.012 16.2 0.8 0.046 14.3 0.8 2.0 1 0 0 1 1 1 0 Bacterial cadherin-like domain Kei1 PF08552.11 EGG22405.1 - 0.038 13.9 8.8 0.88 9.4 0.0 2.8 2 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 SRPRB PF09439.10 EGG22405.1 - 0.083 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit WBP-1 PF11669.8 EGG22405.1 - 0.093 13.4 0.2 0.32 11.7 0.2 1.9 1 0 0 1 1 1 0 WW domain-binding protein 1 FeoB_N PF02421.18 EGG22405.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Na_K-ATPase PF00287.18 EGG22405.1 - 0.12 11.5 0.6 0.25 10.5 0.6 1.4 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain TniB PF05621.11 EGG22405.1 - 0.22 10.9 0.0 0.55 9.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_33 PF13671.6 EGG22405.1 - 0.22 11.7 0.0 0.45 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Lipase_3 PF01764.25 EGG22406.1 - 2e-18 66.6 0.0 5.5e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 EGG22406.1 - 0.086 12.1 0.7 1.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Pkinase_Tyr PF07714.17 EGG22408.1 - 4.8e-52 176.8 0.0 7.8e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG22408.1 - 6.2e-49 166.7 0.1 2.5e-48 164.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 EGG22408.1 - 0.022 14.1 0.0 0.055 12.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2859 PF11072.8 EGG22408.1 - 0.24 11.1 2.3 0.81 9.4 2.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) BPL_N PF09825.9 EGG22408.1 - 1.1 8.3 8.6 1.8 7.5 8.6 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal E7 PF00527.18 EGG22408.1 - 1.3 9.3 5.1 4 7.7 5.1 1.9 1 0 0 1 1 1 0 E7 protein, Early protein TFIIA PF03153.13 EGG22408.1 - 1.4 8.8 26.6 2.4 8.1 26.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4710 PF15828.5 EGG22408.1 - 2 8.6 4.8 4.4 7.5 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Roughex PF06020.11 EGG22408.1 - 2 7.4 10.6 4.2 6.4 10.6 1.5 1 0 0 1 1 1 0 Drosophila roughex protein FAM176 PF14851.6 EGG22408.1 - 3.8 7.2 8.4 7.9 6.1 8.4 1.5 1 0 0 1 1 1 0 FAM176 family EIIBC-GUT_N PF03612.14 EGG22410.1 - 3 7.5 5.6 0.99 9.1 0.8 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Mito_fiss_reg PF05308.11 EGG22410.1 - 9.4 6.2 12.9 0.15 12.1 2.6 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator EF-hand_7 PF13499.6 EGG22411.1 - 1.2e-08 35.3 1.0 2.2e-08 34.4 1.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGG22411.1 - 1e-06 27.8 1.1 2.9e-06 26.4 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EGG22411.1 - 8.6e-06 25.0 0.1 8.6e-06 25.0 0.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGG22411.1 - 8.7e-06 25.3 2.8 2.6e-05 23.8 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF_assoc_2 PF08356.12 EGG22411.1 - 2.9e-05 24.0 0.1 4.5e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 EF hand associated DUF1387 PF07139.11 EGG22411.1 - 0.028 14.2 5.7 0.037 13.8 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) EF_assoc_1 PF08355.12 EGG22411.1 - 0.051 13.2 1.0 0.081 12.5 1.0 1.3 1 0 0 1 1 1 0 EF hand associated SPARC_Ca_bdg PF10591.9 EGG22411.1 - 0.064 13.6 0.9 0.085 13.2 0.5 1.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 EGG22411.1 - 0.074 13.0 0.9 1.2 9.1 0.0 2.5 1 1 2 3 3 3 0 Caleosin related protein CGI-121 PF08617.10 EGG22412.1 - 2.5e-26 92.7 3.1 3e-26 92.5 3.1 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Sin_N PF04801.13 EGG22412.1 - 0.017 14.4 0.1 0.031 13.5 0.1 1.4 1 0 0 1 1 1 0 Sin-like protein conserved region Cyclin PF08613.11 EGG22413.1 - 3.6e-08 33.9 0.0 3.6e-08 33.9 0.0 3.2 3 1 1 4 4 4 1 Cyclin Cyclin_N PF00134.23 EGG22413.1 - 0.0064 16.2 0.0 0.0064 16.2 0.0 3.0 3 1 0 3 3 3 1 Cyclin, N-terminal domain Activator_LAG-3 PF11498.8 EGG22413.1 - 0.11 11.4 33.1 0.024 13.6 19.6 3.0 3 0 0 3 3 3 0 Transcriptional activator LAG-3 Cyclin_C PF02984.19 EGG22413.1 - 1.4 9.0 7.7 0.45 10.6 0.2 2.5 2 0 0 2 2 2 0 Cyclin, C-terminal domain Mucin PF01456.17 EGG22413.1 - 2.8 7.9 14.6 6.7 6.7 0.4 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.8 EGG22413.1 - 4.9 7.1 10.1 17 5.4 6.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) JTB PF05439.12 EGG22414.1 - 2.4e-10 40.4 1.8 5.2e-10 39.3 0.9 1.9 2 0 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) Dehydrin PF00257.19 EGG22414.1 - 0.02 15.4 2.2 0.038 14.6 2.2 1.6 1 0 0 1 1 1 0 Dehydrin PA26 PF04636.13 EGG22414.1 - 0.08 11.9 2.7 0.11 11.4 2.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Connexin PF00029.19 EGG22414.1 - 0.39 10.4 4.5 0.76 9.5 1.5 2.2 2 1 0 2 2 2 0 Connexin Menin PF05053.13 EGG22414.1 - 0.71 8.2 15.4 0.97 7.7 15.4 1.1 1 0 0 1 1 1 0 Menin Ly49 PF08391.10 EGG22414.1 - 8.9 6.7 13.1 15 5.9 8.7 2.9 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region PALP PF00291.25 EGG22415.1 - 1.7e-70 237.7 0.5 2.1e-70 237.5 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LpxI_N PF17930.1 EGG22415.1 - 0.016 15.1 0.1 0.062 13.2 0.0 2.0 2 0 0 2 2 2 0 LpxI N-terminal domain SieB PF14163.6 EGG22415.1 - 0.053 13.0 0.6 2.4 7.7 0.1 2.5 2 0 0 2 2 2 0 Super-infection exclusion protein B ResIII PF04851.15 EGG22416.1 - 4.9e-20 72.2 0.0 4.9e-20 72.2 0.0 4.7 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGG22416.1 - 5e-20 71.9 0.0 2.1e-19 69.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGG22416.1 - 3.1e-13 49.9 0.0 8.6e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myosin_TH1 PF06017.13 EGG22417.1 - 1.3e-08 34.8 1.5 6.4e-06 26.0 0.6 2.2 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding PapJ PF14855.6 EGG22417.1 - 0.24 11.1 2.8 0.68 9.6 0.0 2.8 3 1 1 4 4 4 0 Pilus-assembly fibrillin subunit, chaperone PP2C PF00481.21 EGG22418.1 - 4.1e-67 226.5 0.0 4.1e-67 226.5 0.0 3.5 4 0 0 4 4 4 1 Protein phosphatase 2C Ribosomal_S13 PF00416.22 EGG22418.1 - 1.5e-47 161.2 1.5 1.5e-47 161.2 1.5 3.2 3 0 0 3 3 3 1 Ribosomal protein S13/S18 G-alpha PF00503.20 EGG22418.1 - 4.5e-34 118.1 0.3 4.5e-34 118.1 0.3 5.5 5 2 1 6 6 6 1 G-protein alpha subunit OGG_N PF07934.12 EGG22419.1 - 0.092 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain Pkinase PF00069.25 EGG22420.1 - 1.5e-68 231.0 0.0 5.1e-45 153.9 0.5 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG22420.1 - 3e-27 95.5 0.0 2.1e-22 79.6 0.4 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGG22420.1 - 6.5e-05 22.4 0.1 0.00032 20.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGG22420.1 - 0.00018 21.5 0.1 0.0025 17.8 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGG22420.1 - 0.0037 16.4 0.0 0.0073 15.4 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EGG22420.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-BED PF02892.15 EGG22420.1 - 0.19 11.8 0.2 0.6 10.2 0.2 1.8 1 0 0 1 1 1 0 BED zinc finger 2OG-FeII_Oxy PF03171.20 EGG22421.1 - 1.9e-24 86.1 0.0 3.7e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGG22421.1 - 9e-21 74.8 0.1 2.2e-20 73.5 0.1 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Mlh1_C PF16413.5 EGG22422.1 - 0.031 13.7 1.3 0.067 12.6 1.0 1.5 1 1 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus FAM176 PF14851.6 EGG22422.1 - 1.2 8.8 6.3 0.092 12.4 0.8 1.9 2 1 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 EGG22422.1 - 1.3 9.0 13.0 0.025 14.6 5.1 2.0 2 1 1 3 3 3 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 EGG22422.1 - 3.2 8.2 18.8 1.1 9.7 15.3 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TFIIF_alpha PF05793.12 EGG22422.1 - 4.8 5.6 15.8 4.7 5.7 0.5 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TipE PF16972.5 EGG22422.1 - 8.8 5.4 14.2 0.045 12.9 1.4 2.1 2 0 0 2 2 2 0 Na+ channel auxiliary subunit TipE GP67 PF17634.2 EGG22422.1 - 9.5 6.7 23.8 0.071 13.5 15.4 1.7 2 0 0 2 2 2 0 Gene product 67 RNA_pol_3_Rpc31 PF11705.8 EGG22422.1 - 9.7 6.4 20.7 28 4.8 20.7 1.8 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FNIP PF05725.12 EGG22423.1 - 1.2e-18 67.0 30.2 1.1e-07 31.9 0.0 9.4 8 1 4 12 12 12 8 FNIP Repeat Zip PF02535.22 EGG22425.1 - 9e-50 169.8 4.1 1.2e-49 169.4 4.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SieB PF14163.6 EGG22425.1 - 0.075 12.5 0.6 1.3 8.5 0.6 2.6 1 1 0 1 1 1 0 Super-infection exclusion protein B HCO3_cotransp PF00955.21 EGG22426.1 - 2.1e-105 353.5 21.9 6.7e-58 196.8 7.7 2.1 1 1 1 2 2 2 2 HCO3- transporter family Sulfate_transp PF00916.20 EGG22426.1 - 0.005 15.6 18.7 0.081 11.7 18.7 2.4 1 1 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 EGG22426.1 - 9.7 6.6 11.7 3.8 8.0 4.5 3.3 2 2 1 3 3 3 0 Molybdate transporter of MFS superfamily Pro_isomerase PF00160.21 EGG22428.1 - 5.6e-43 147.0 0.5 6.6e-43 146.7 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Spec3 PF15795.5 EGG22428.1 - 7.1e-07 29.7 19.1 0.00027 21.4 19.1 2.4 1 1 0 1 1 1 1 Ectodermal ciliogenesis protein HIT PF01230.23 EGG22429.1 - 4.3e-25 88.3 0.1 6.3e-25 87.8 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGG22429.1 - 5.4e-07 30.1 0.1 1e-06 29.2 0.1 1.4 1 1 1 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGG22429.1 - 0.0026 17.6 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 UCH PF00443.29 EGG22430.1 - 4.5e-55 186.9 3.4 1.7e-54 185.0 3.4 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG22430.1 - 2.4e-11 43.8 21.3 1.3e-08 34.8 0.1 3.5 3 2 1 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase PXA PF02194.15 EGG22430.1 - 0.54 10.2 2.3 15 5.5 0.3 2.9 2 1 0 2 2 2 0 PXA domain FYVE PF01363.21 EGG22431.1 - 6.1e-19 67.9 6.0 1.1e-18 67.1 6.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger Pkinase_Tyr PF07714.17 EGG22431.1 - 9.7e-05 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG22431.1 - 0.00014 21.3 0.1 0.0044 16.4 0.1 2.3 2 0 0 2 2 2 1 Protein kinase domain WH2 PF02205.20 EGG22431.1 - 0.0046 16.7 0.1 0.016 15.1 0.1 2.0 1 0 0 1 1 1 1 WH2 motif FYVE_2 PF02318.16 EGG22431.1 - 0.24 11.6 4.7 0.51 10.6 4.7 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 EGG22431.1 - 1.4 9.0 9.2 13 5.9 1.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 EGG22431.1 - 8.8 6.3 8.0 8 6.5 0.1 3.1 1 1 1 2 2 2 0 zinc-ribbon domain Ank_2 PF12796.7 EGG22432.1 - 4.3e-30 104.1 20.3 2.6e-08 34.3 0.2 6.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22432.1 - 6e-26 90.2 21.1 3.8e-05 23.9 0.1 11.1 2 2 11 13 13 13 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22432.1 - 2.1e-23 82.4 11.8 0.00052 20.5 0.1 7.6 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22432.1 - 8.2e-17 59.6 12.2 0.039 14.5 0.0 10.4 10 1 2 12 12 12 3 Ankyrin repeat Ank PF00023.30 EGG22432.1 - 2.9e-10 40.1 10.7 0.89 10.1 0.0 8.0 6 3 2 8 8 8 4 Ankyrin repeat DUF5049 PF16468.5 EGG22432.1 - 0.0079 16.1 0.5 2.3 8.2 0.0 4.9 6 0 0 6 6 6 1 Domain of unknown function (DUF5049) Gln_deamidase_2 PF18626.1 EGG22432.1 - 0.021 15.0 0.8 0.054 13.7 0.1 2.1 2 1 0 2 2 2 0 Glutaminase DUF3447 PF11929.8 EGG22432.1 - 0.1 12.5 12.1 0.034 14.1 2.6 4.1 3 1 2 5 5 5 0 Domain of unknown function (DUF3447) CxC2 PF18803.1 EGG22432.1 - 0.41 10.8 3.4 0.65 10.2 0.1 2.8 3 0 0 3 3 3 0 CxC2 like cysteine cluster associated with KDZ transposases ERCC4 PF02732.15 EGG22433.1 - 1.9e-15 57.4 0.0 1.9e-15 57.4 0.0 3.9 3 1 1 4 4 4 1 ERCC4 domain PTPS_related PF10131.9 EGG22433.1 - 0.062 11.6 0.0 0.093 11.0 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein AT_hook PF02178.19 EGG22433.1 - 7.1 6.9 8.8 0.34 10.9 3.1 1.9 2 0 0 2 2 2 0 AT hook motif CBM49 PF09478.10 EGG22434.1 - 3.4e-13 49.7 0.1 4.7e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM_2 PF00553.19 EGG22434.1 - 0.058 13.7 0.1 0.088 13.1 0.1 1.3 1 1 0 1 1 1 0 Cellulose binding domain DP PF08781.10 EGG22435.1 - 1.3e-26 93.1 18.1 1.3e-26 93.1 18.1 2.3 2 1 0 2 2 2 1 Transcription factor DP E2F_TDP PF02319.20 EGG22435.1 - 3.7e-20 71.7 1.5 3.7e-20 71.7 1.5 2.0 3 0 0 3 3 3 1 E2F/DP family winged-helix DNA-binding domain FKBP_C PF00254.28 EGG22436.1 - 7.2e-31 106.4 0.0 9.4e-31 106.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Spectrin_like PF18373.1 EGG22437.1 - 0.051 13.6 1.2 0.34 11.0 0.2 2.7 3 0 0 3 3 3 0 Spectrin like domain COPI_C PF06957.11 EGG22438.1 - 2.2e-145 484.5 0.0 2.8e-145 484.1 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 EGG22438.1 - 1.4e-120 403.4 3.2 1.5e-120 403.2 0.9 2.2 2 1 1 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 EGG22438.1 - 2.7e-44 148.2 10.7 2.5e-08 34.4 0.0 8.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG22438.1 - 1.5e-08 34.8 0.1 0.47 10.8 0.0 5.8 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG22438.1 - 0.025 13.2 3.8 1.4 7.5 0.3 3.4 2 1 2 4 4 4 0 Nucleoporin Nup120/160 DUF3151 PF11349.8 EGG22438.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3151) zf-LSD1 PF06943.12 EGG22438.1 - 0.12 12.2 0.3 0.26 11.2 0.3 1.6 1 0 0 1 1 1 0 LSD1 zinc finger HTH_9 PF08221.11 EGG22439.1 - 2e-14 53.4 0.8 9.7e-09 35.2 0.0 3.5 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 EGG22439.1 - 5.7e-13 49.2 17.7 1e-09 38.6 7.3 4.4 3 1 1 4 4 4 3 RNA polymerase III subunit RPC82 TrmB PF01978.19 EGG22439.1 - 1.4e-05 24.9 0.3 0.25 11.2 0.0 3.3 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 EGG22439.1 - 0.0039 17.0 10.9 0.026 14.4 0.4 4.4 3 1 0 4 4 4 2 TFIIE alpha subunit Sel1 PF08238.12 EGG22441.1 - 3.7e-30 103.7 8.6 2.6e-06 27.9 0.0 9.6 11 0 0 11 11 11 4 Sel1 repeat TPR_6 PF13174.6 EGG22441.1 - 0.0097 16.5 3.2 7.2 7.5 0.2 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat DUF3232 PF11554.8 EGG22441.1 - 0.026 14.9 0.1 0.084 13.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) TPR_1 PF00515.28 EGG22441.1 - 0.074 12.9 12.6 13 5.8 1.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGG22441.1 - 0.18 12.3 2.2 20 5.8 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGG22441.1 - 0.22 11.3 5.5 8.8 6.1 0.1 4.3 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.17 EGG22441.1 - 0.66 10.2 15.8 5.5 7.4 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF4326 PF14216.6 EGG22443.1 - 4.5e-20 72.2 0.2 4.5e-20 72.2 0.2 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4326) DUF4197 PF13852.6 EGG22443.1 - 0.0089 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4197) TfoX_N PF04993.13 EGG22443.1 - 0.1 12.8 0.4 0.3 11.3 0.1 1.8 2 0 0 2 2 2 0 TfoX N-terminal domain Cellulase PF00150.18 EGG22444.1 - 1.4e-26 93.6 2.0 3.1e-26 92.4 2.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PKHD_C PF18331.1 EGG22446.1 - 0.0072 16.4 0.6 0.035 14.2 0.1 2.3 2 0 0 2 2 2 1 PKHD-type hydroxylase C-terminal domain Filament PF00038.21 EGG22446.1 - 0.0074 15.9 10.1 0.0074 15.9 10.1 1.3 1 1 0 1 1 1 1 Intermediate filament protein DUF745 PF05335.13 EGG22446.1 - 0.061 13.0 6.5 0.08 12.7 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF2968 PF11180.8 EGG22446.1 - 0.061 12.9 8.7 0.15 11.7 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Lebercilin PF15619.6 EGG22446.1 - 0.068 12.8 13.1 0.15 11.7 13.1 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4407 PF14362.6 EGG22446.1 - 0.21 10.9 5.7 0.4 10.0 5.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YozE_SAM_like PF06855.12 EGG22446.1 - 0.21 11.8 3.6 0.12 12.6 1.1 1.9 2 0 0 2 2 2 0 YozE SAM-like fold Allexi_40kDa PF05549.11 EGG22446.1 - 0.34 10.4 5.0 0.39 10.2 5.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein FlaC_arch PF05377.11 EGG22446.1 - 0.44 11.0 13.0 0.12 12.8 1.0 3.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Phage_HK97_TLTM PF06120.11 EGG22446.1 - 0.75 8.9 13.3 0.83 8.8 13.3 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Exonuc_VII_L PF02601.15 EGG22446.1 - 0.91 9.0 6.8 0.96 8.9 6.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PKcGMP_CC PF16808.5 EGG22446.1 - 1.2 9.0 0.1 1.2 9.0 0.1 3.3 4 0 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2524 PF10732.9 EGG22446.1 - 1.5 9.1 11.1 1.6 9.1 4.4 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF2524) DUF4094 PF13334.6 EGG22446.1 - 1.6 9.2 5.4 0.27 11.7 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) GrpE PF01025.19 EGG22446.1 - 1.6 8.4 11.5 4.3 7.0 11.5 1.9 1 1 0 1 1 1 0 GrpE Cellulase PF00150.18 EGG22447.1 - 2.4e-29 102.6 0.5 3.4e-29 102.2 0.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pentapeptide PF00805.22 EGG22448.1 - 1.2e-19 69.6 19.1 2.5e-06 27.0 0.2 4.5 1 1 1 4 4 4 4 Pentapeptide repeats (8 copies) BTB_2 PF02214.22 EGG22448.1 - 5.1e-16 58.8 0.1 2.2e-15 56.8 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Pentapeptide_4 PF13599.6 EGG22448.1 - 2.8e-12 46.6 16.6 4.5e-08 33.1 6.2 3.6 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EGG22448.1 - 5.9e-12 45.5 17.8 3e-06 27.3 5.2 3.9 2 1 1 3 3 3 3 Pentapeptide repeats (9 copies) PPL5 PF18168.1 EGG22448.1 - 0.01 15.2 1.1 0.018 14.3 1.1 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Sorting_nexin PF03700.13 EGG22448.1 - 5.5 7.6 16.2 0.085 13.4 5.5 2.6 2 0 0 2 2 2 0 Sorting nexin, N-terminal domain Asn_synthase PF00733.21 EGG22449.1 - 1.9e-99 333.7 0.0 5.3e-57 194.1 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EGG22449.1 - 1.6e-41 141.0 0.0 2.9e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGG22449.1 - 5.2e-31 107.6 0.0 8.3e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGG22449.1 - 7.3e-14 51.8 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EGG22449.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 NAD synthase NmrA PF05368.13 EGG22451.1 - 7.4e-19 68.2 0.5 1.1e-18 67.7 0.5 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGG22451.1 - 1.1e-05 25.4 0.1 1.9e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EGG22451.1 - 5e-05 23.3 0.0 9.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EGG22451.1 - 0.00054 19.0 0.1 0.00077 18.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EGG22451.1 - 0.053 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Ank_2 PF12796.7 EGG22452.1 - 1.1e-12 48.4 2.7 0.17 12.5 0.0 6.5 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22452.1 - 9.7e-08 32.4 5.4 0.84 10.3 0.2 6.7 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22452.1 - 1.7e-06 27.9 6.2 16 6.5 0.0 8.5 9 0 0 9 9 9 1 Ankyrin repeat zf-TRAF PF02176.18 EGG22452.1 - 5.6e-06 26.9 32.9 1.1e-05 26.0 5.6 3.1 3 0 0 3 3 3 2 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EGG22452.1 - 8e-06 26.2 15.1 5.3e-05 23.6 4.8 2.7 1 1 1 2 2 2 2 TRAF-like zinc-finger Sina PF03145.16 EGG22452.1 - 0.0028 17.6 21.3 0.034 14.1 3.6 3.3 1 1 2 3 3 3 2 Seven in absentia protein family DUF3876 PF12992.7 EGG22452.1 - 0.018 15.1 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) Peptidase_M49 PF03571.15 EGG22452.1 - 0.031 12.7 0.4 0.057 11.8 0.4 1.3 1 0 0 1 1 1 0 Peptidase family M49 zf-TRAF PF02176.18 EGG22453.1 - 2.6e-09 37.6 30.1 3.5e-07 30.8 3.4 3.5 3 0 0 3 3 3 2 TRAF-type zinc finger Sina PF03145.16 EGG22453.1 - 9.6e-06 25.7 17.1 0.0073 16.3 2.1 3.2 1 1 2 3 3 3 3 Seven in absentia protein family zf-TRAF_2 PF15965.5 EGG22453.1 - 0.00015 22.1 3.1 0.00015 22.1 3.1 2.9 2 1 1 3 3 3 2 TRAF-like zinc-finger DivIC PF04977.15 EGG22453.1 - 0.035 13.9 1.8 0.064 13.0 1.8 1.4 1 0 0 1 1 1 0 Septum formation initiator Cytochrom_C1 PF02167.15 EGG22453.1 - 0.057 13.1 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C1 family Thiolase_N PF00108.23 EGG22454.1 - 1.7e-79 266.8 4.3 3.4e-79 265.9 4.3 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGG22454.1 - 6.5e-47 158.2 0.7 6.5e-47 158.2 0.7 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain Ank_2 PF12796.7 EGG22454.1 - 8.4e-09 35.9 7.9 0.064 13.8 0.0 6.1 4 2 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22454.1 - 4.4e-07 30.1 1.3 0.17 12.2 0.1 5.3 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22454.1 - 6.4e-07 29.8 10.7 3.2 8.5 0.4 7.8 6 3 2 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22454.1 - 0.00053 20.2 9.3 35 5.4 0.0 7.8 8 0 0 8 8 8 0 Ankyrin repeat ketoacyl-synt PF00109.26 EGG22454.1 - 0.0051 16.4 0.7 0.013 15.1 0.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain MMR_HSR1 PF01926.23 EGG22455.1 - 1.8e-21 76.4 1.4 5e-21 74.9 0.6 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase KH_2 PF07650.17 EGG22455.1 - 2.7e-11 43.1 0.1 7e-11 41.8 0.1 1.8 1 0 0 1 1 1 1 KH domain Dynamin_N PF00350.23 EGG22455.1 - 3.8e-09 36.8 6.5 1.6e-05 25.0 0.1 3.6 3 1 1 4 4 4 2 Dynamin family FeoB_N PF02421.18 EGG22455.1 - 6e-08 32.4 0.1 6e-08 32.4 0.1 2.3 1 1 1 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 EGG22455.1 - 9.6e-08 31.6 0.6 1.8e-07 30.7 0.3 1.6 1 1 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EGG22455.1 - 3.2e-06 27.2 1.7 0.00063 19.7 0.1 2.6 2 1 1 3 3 3 2 RsgA GTPase ATP_bind_1 PF03029.17 EGG22455.1 - 0.00028 20.7 1.6 0.0028 17.5 0.7 2.5 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EGG22455.1 - 0.00063 19.5 0.6 0.16 11.8 0.1 3.2 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EGG22455.1 - 0.0042 16.6 4.6 0.13 11.8 4.5 3.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 EGG22455.1 - 0.015 14.7 0.1 0.074 12.4 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.27 EGG22455.1 - 0.06 13.9 0.7 0.24 11.9 0.2 2.4 2 1 0 2 2 2 0 ABC transporter MMR_HSR1_Xtn PF16897.5 EGG22455.1 - 0.12 12.4 2.8 0.62 10.1 0.1 3.3 3 1 0 3 3 3 0 C-terminal region of MMR_HSR1 domain Roc PF08477.13 EGG22455.1 - 0.13 12.5 1.0 0.87 9.8 0.0 2.8 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MutS_III PF05192.18 EGG22455.1 - 0.17 12.1 0.7 0.3 11.3 0.2 1.7 2 0 0 2 2 2 0 MutS domain III cobW PF02492.19 EGG22455.1 - 0.7 9.5 4.0 4.4 6.9 4.0 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RCC1 PF00415.18 EGG22456.1 - 2.9e-73 242.3 4.3 1.9e-12 47.6 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG22456.1 - 1.3e-38 130.0 18.1 6.5e-09 35.4 1.5 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat GGDEF PF00990.21 EGG22457.1 - 4.3e-34 117.6 0.9 4.3e-34 117.6 0.9 1.7 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain Guanylate_cyc PF00211.20 EGG22457.1 - 0.015 15.0 0.2 0.023 14.3 0.2 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain DUF4015 PF13200.6 EGG22458.1 - 0.00012 21.3 1.1 0.00024 20.3 1.1 1.5 1 0 0 1 1 1 1 Putative glycosyl hydrolase domain zf-CCHC PF00098.23 EGG22458.1 - 0.003 17.6 1.3 0.003 17.6 1.3 3.0 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGG22458.1 - 0.64 9.8 5.9 4.8 7.0 1.5 2.7 2 0 0 2 2 2 0 Zinc knuckle DUF4457 PF14652.6 EGG22459.1 - 2.7e-143 477.1 15.3 1.2e-99 333.7 3.5 3.2 2 1 1 3 3 3 3 Domain of unknown function (DUF4457) F5_F8_type_C PF00754.25 EGG22459.1 - 0.0063 16.6 0.0 0.0063 16.6 0.0 3.6 3 0 0 3 3 3 1 F5/8 type C domain ExbD PF02472.16 EGG22460.1 - 0.057 13.6 0.0 0.087 13.0 0.0 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR MIP-T3 PF10243.9 EGG22460.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH-like domain V-SNARE_C PF12352.8 EGG22461.1 - 0.00019 21.7 2.8 0.00019 21.7 2.8 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 EGG22461.1 - 0.00022 21.5 1.6 0.00022 21.5 1.6 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Prominin PF05478.11 EGG22461.1 - 0.0007 17.7 3.2 0.001 17.2 3.2 1.1 1 0 0 1 1 1 1 Prominin Sec20 PF03908.13 EGG22461.1 - 0.00085 19.2 2.4 0.00085 19.2 2.4 2.2 2 1 1 3 3 3 1 Sec20 SNARE PF05739.19 EGG22461.1 - 0.016 15.2 5.6 0.025 14.5 4.0 2.2 3 0 0 3 3 3 0 SNARE domain GP41 PF00517.17 EGG22461.1 - 0.057 13.3 0.4 0.057 13.3 0.4 1.5 2 0 0 2 2 2 0 Retroviral envelope protein DUF4199 PF13858.6 EGG22461.1 - 0.069 13.5 4.4 0.13 12.7 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) DUF3533 PF12051.8 EGG22461.1 - 0.17 10.8 0.3 0.24 10.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) KxDL PF10241.9 EGG22461.1 - 0.24 11.7 12.2 2.3 8.6 5.9 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF2721 PF11026.8 EGG22461.1 - 0.53 10.2 3.3 9.7 6.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) CCDC-167 PF15188.6 EGG22461.1 - 0.79 10.1 9.1 4.2 7.8 0.1 2.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 FeoB_associated PF12669.7 EGG22461.1 - 0.85 10.1 2.2 1.4 9.4 2.2 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF4558 PF15104.6 EGG22461.1 - 1 9.4 11.2 2.2 8.4 1.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4558) DUF724 PF05266.14 EGG22461.1 - 2.1 8.1 10.1 0.75 9.6 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) MRPL52 PF18699.1 EGG22461.1 - 2.9 8.1 9.5 1.8 8.8 1.4 3.1 3 0 0 3 3 3 0 Mitoribosomal protein mL52 Fzo_mitofusin PF04799.13 EGG22461.1 - 5.8 6.4 9.5 3.9 7.0 0.1 3.0 2 1 1 3 3 3 0 fzo-like conserved region Snapin_Pallidin PF14712.6 EGG22461.1 - 6.9 7.2 10.7 0.6 10.6 1.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin TMPIT PF07851.13 EGG22461.1 - 6.9 5.8 8.7 11 5.2 0.7 2.1 2 0 0 2 2 2 0 TMPIT-like protein MCU PF04678.13 EGG22461.1 - 9.3 6.3 10.2 1.6e+02 2.3 10.2 2.3 1 1 0 1 1 1 0 Mitochondrial calcium uniporter PCI PF01399.27 EGG22462.1 - 8.7e-13 48.7 0.3 8.7e-13 48.7 0.3 2.3 2 1 0 2 2 2 1 PCI domain Sas10_Utp3 PF04000.15 EGG22462.1 - 0.029 15.0 0.2 0.73 10.5 0.0 3.2 2 1 1 3 3 3 0 Sas10/Utp3/C1D family SF3b10 PF07189.11 EGG22462.1 - 0.097 12.8 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 Splicing factor 3B subunit 10 (SF3b10) DUF5383 PF17355.2 EGG22463.1 - 0.06 13.7 0.6 0.15 12.5 0.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Ank_2 PF12796.7 EGG22464.1 - 6.9e-46 154.8 13.0 1.2e-08 35.4 0.5 7.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22464.1 - 5.2e-36 122.2 9.0 0.0038 17.5 0.0 13.3 3 2 12 15 15 15 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22464.1 - 5.7e-36 122.4 12.1 5e-05 23.8 0.0 12.2 4 4 12 16 16 16 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22464.1 - 2.7e-22 76.4 12.6 2.4 9.0 0.0 16.8 18 2 2 20 20 20 1 Ankyrin repeat DUF5049 PF16468.5 EGG22464.1 - 3e-10 39.8 9.8 24 4.9 0.0 12.6 9 2 7 16 16 16 0 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22464.1 - 3.3e-10 40.0 0.0 24 5.6 0.0 11.5 8 6 2 10 10 10 0 Ankyrin repeat Vps23_core PF09454.10 EGG22464.1 - 0.0026 17.7 1.3 1e+02 3.0 0.0 7.2 9 1 1 10 10 10 0 Vps23 core domain DUF1676 PF07898.13 EGG22464.1 - 0.081 13.0 0.7 12 5.9 0.1 3.9 3 2 1 4 4 4 0 Protein of unknown function (DUF1676) UTP15_C PF09384.10 EGG22464.1 - 0.087 12.5 0.1 6.5 6.4 0.0 3.2 3 0 0 3 3 3 0 UTP15 C terminal NanE PF04131.14 EGG22464.1 - 0.14 11.3 0.4 32 3.6 0.0 3.4 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase HALZ PF02183.18 EGG22465.1 - 0.066 13.4 1.1 0.86 9.9 0.0 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Ank_3 PF13606.6 EGG22465.1 - 0.12 13.0 0.2 2.7e+02 2.7 0.0 5.3 4 0 0 4 4 4 0 Ankyrin repeat CHASE5 PF17149.4 EGG22465.1 - 0.16 11.9 2.8 0.72 9.8 0.1 2.6 2 0 0 2 2 2 0 Periplasmic sensor domain found in signal transduction proteins Resolvase PF00239.21 EGG22466.1 - 0.00051 20.2 0.1 0.034 14.2 0.0 3.3 4 0 0 4 4 4 1 Resolvase, N terminal domain VPS9 PF02204.18 EGG22467.1 - 8.2e-10 38.8 2.2 1.9e-09 37.7 2.2 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Pkinase PF00069.25 EGG22468.1 - 5.7e-68 229.1 0.0 1e-67 228.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG22468.1 - 3e-52 177.5 0.2 4.7e-52 176.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG22468.1 - 2.9e-07 29.6 0.1 6e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase RasGAP PF00616.19 EGG22470.1 - 5.2e-31 108.0 0.2 1.7e-23 83.4 0.1 4.4 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase Med4 PF10018.9 EGG22470.1 - 0.00078 19.2 3.2 0.00078 19.2 3.2 2.9 3 0 0 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 GST_C_3 PF14497.6 EGG22471.1 - 4.3e-23 81.4 0.1 6.1e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG22471.1 - 9e-08 32.2 0.0 1.4e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGG22471.1 - 4.7e-07 30.1 0.0 1.1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGG22471.1 - 4.6e-05 23.7 0.0 0.00016 22.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EGG22471.1 - 0.0028 18.4 0.0 0.0052 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 EGG22471.1 - 0.013 15.5 0.1 0.032 14.2 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Arf PF00025.21 EGG22472.1 - 2.6e-44 150.8 0.0 2.9e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGG22472.1 - 3.5e-25 88.5 0.0 4e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG22472.1 - 1.7e-18 67.0 0.0 2.4e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGG22472.1 - 1.8e-10 40.6 0.0 2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGG22472.1 - 1.5e-09 37.5 0.0 1.7e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGG22472.1 - 3e-08 33.7 0.0 5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGG22472.1 - 5.8e-08 32.3 1.2 1.5e-05 24.3 0.0 2.7 1 1 1 2 2 2 2 G-protein alpha subunit ATP_bind_1 PF03029.17 EGG22472.1 - 0.0011 18.8 0.1 1.4 8.6 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein NACHT PF05729.12 EGG22472.1 - 0.004 17.1 0.1 2.8 7.8 0.1 2.1 2 0 0 2 2 2 2 NACHT domain RsgA_GTPase PF03193.16 EGG22472.1 - 0.0062 16.5 0.6 2.6 7.9 0.2 2.2 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 EGG22472.1 - 0.013 16.1 0.5 0.028 14.9 0.5 1.7 1 1 0 1 1 1 0 ABC transporter MMR_HSR1_Xtn PF16897.5 EGG22472.1 - 0.013 15.5 0.2 0.02 14.9 0.2 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain cobW PF02492.19 EGG22472.1 - 0.015 14.9 0.7 0.72 9.4 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EGG22472.1 - 0.05 13.9 0.1 0.56 10.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG22472.1 - 0.065 13.6 0.1 0.15 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EGG22472.1 - 0.1 12.3 0.4 3.3 7.5 0.1 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EGG22472.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGG22472.1 - 0.13 12.4 0.1 0.37 10.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain GST_N PF02798.20 EGG22472.1 - 0.15 12.4 0.1 0.34 11.3 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Metallophos PF00149.28 EGG22473.1 - 1.6e-09 38.5 0.0 5.3e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG22473.1 - 0.00034 20.8 0.0 0.00091 19.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIIF_alpha PF05793.12 EGG22474.1 - 0.044 12.4 29.4 0.056 12.0 29.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 EGG22474.1 - 0.14 10.4 30.7 0.16 10.1 30.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EGG22474.1 - 6.6 6.0 27.8 8.7 5.6 27.8 1.2 1 0 0 1 1 1 0 BUD22 Thioredoxin PF00085.20 EGG22475.1 - 2.1e-32 111.2 0.7 4.2e-24 84.5 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin Nop14 PF04147.12 EGG22475.1 - 0.00049 18.5 17.6 0.0006 18.2 17.6 1.1 1 0 0 1 1 1 1 Nop14-like family SUIM_assoc PF16619.5 EGG22475.1 - 0.0008 19.4 0.6 0.0011 18.9 0.6 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 CDC45 PF02724.14 EGG22475.1 - 0.0014 17.0 7.8 0.0016 16.8 7.8 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF2125 PF09898.9 EGG22475.1 - 0.0029 17.3 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2125) Thioredoxin_2 PF13098.6 EGG22475.1 - 0.0044 17.5 1.4 0.05 14.1 0.2 2.8 2 2 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EGG22475.1 - 0.018 15.0 0.6 0.036 14.0 0.1 1.9 2 1 0 2 2 2 0 AhpC/TSA family DUF223 PF02721.14 EGG22475.1 - 0.045 14.0 0.0 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF223 SDA1 PF05285.12 EGG22475.1 - 0.063 12.7 16.0 0.083 12.3 16.0 1.2 1 0 0 1 1 1 0 SDA1 Thioredoxin_8 PF13905.6 EGG22475.1 - 0.095 13.0 5.2 0.43 10.9 0.0 3.5 2 2 1 4 4 4 0 Thioredoxin-like RRN3 PF05327.11 EGG22475.1 - 0.45 9.0 8.6 0.54 8.7 8.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.11 EGG22475.1 - 9.8 5.7 25.8 15 5.1 25.8 1.3 1 0 0 1 1 1 0 PPP4R2 UPF0160 PF03690.13 EGG22476.1 - 6.6e-120 400.5 0.6 7.8e-120 400.3 0.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) RRF PF01765.19 EGG22477.1 - 2.1e-46 157.9 6.5 3.5e-46 157.1 6.5 1.3 1 0 0 1 1 1 1 Ribosome recycling factor DCB PF16213.5 EGG22477.1 - 0.14 11.8 3.0 0.27 10.9 3.0 1.5 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 eIF_4EBP PF05456.11 EGG22477.1 - 0.37 10.8 3.1 0.19 11.7 0.4 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DinI PF06183.13 EGG22477.1 - 0.44 10.9 3.4 1.4 9.3 0.5 2.8 3 0 0 3 3 3 0 DinI-like family CTP_transf_like PF01467.26 EGG22478.1 - 7.7e-29 100.7 0.1 7.7e-29 100.7 0.1 2.4 2 1 0 2 2 2 1 Cytidylyltransferase-like AAA_18 PF13238.6 EGG22479.1 - 8.4e-06 26.4 0.0 2.8e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGG22479.1 - 0.0002 20.7 0.0 0.00044 19.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EGG22479.1 - 0.0011 19.1 0.1 0.004 17.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EGG22479.1 - 0.0017 18.6 0.1 0.0043 17.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGG22479.1 - 0.013 15.9 0.4 0.083 13.3 0.4 2.4 1 1 0 1 1 1 0 RNA helicase Rad17 PF03215.15 EGG22479.1 - 0.036 14.0 0.3 0.13 12.1 0.2 1.9 1 1 1 2 2 2 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGG22479.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EGG22479.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain APS_kinase PF01583.20 EGG22479.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 EGG22479.1 - 0.15 11.8 0.4 1.3 8.7 0.1 2.1 1 1 1 2 2 2 0 Cytidylate kinase AAA PF00004.29 EGG22479.1 - 0.17 12.3 0.2 0.5 10.8 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGG22479.1 - 0.35 10.4 0.7 0.76 9.3 0.7 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGG22479.1 - 1.4 9.4 6.6 0.29 11.7 2.1 2.4 2 1 0 2 2 2 0 ABC transporter Dscam_C PF12355.8 EGG22479.1 - 1.9 9.4 13.7 1.8 9.5 1.4 3.3 3 0 0 3 3 3 0 Down syndrome cell adhesion molecule C terminal AAA_23 PF13476.6 EGG22479.1 - 4 7.9 6.8 65 3.9 0.2 3.7 4 0 0 4 4 4 0 AAA domain DHHC PF01529.20 EGG22480.1 - 1.6e-35 122.1 7.3 1.6e-35 122.1 7.3 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3112 PF11309.8 EGG22480.1 - 0.0063 16.0 3.9 0.0095 15.4 3.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3112) VATC PF18716.1 EGG22481.1 - 0.052 13.4 0.4 0.1 12.5 0.4 1.4 1 0 0 1 1 1 0 Vms1-associating treble clef domain AsmA_1 PF13109.6 EGG22483.1 - 0.16 11.4 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 AsmA-like C-terminal region FHA PF00498.26 EGG22485.1 - 3.4e-18 65.7 0.1 3.4e-18 65.7 0.1 2.2 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EGG22485.1 - 8.5e-08 32.4 0.0 2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Voltage_CLC PF00654.20 EGG22486.1 - 1.6e-104 349.9 24.3 1.6e-104 349.9 24.3 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGG22486.1 - 1.1e-21 77.0 0.1 4.9e-10 39.7 0.0 2.7 2 0 0 2 2 2 2 CBS domain DUF4257 PF14074.6 EGG22486.1 - 0.82 9.9 7.2 6.2 7.1 1.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) PTPRCAP PF15713.5 EGG22486.1 - 1.2 9.4 7.8 2.5 8.4 7.8 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated BSD PF03909.17 EGG22487.1 - 2.8e-09 36.8 0.3 8.6e-09 35.3 0.3 2.0 1 0 0 1 1 1 1 BSD domain Prp19 PF08606.11 EGG22488.1 - 9.8e-35 118.4 0.6 1.7e-34 117.6 0.6 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 EGG22488.1 - 6.5e-28 96.4 18.4 4e-09 36.9 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG22488.1 - 4.6e-14 52.5 0.7 0.00031 21.0 0.0 5.1 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGG22488.1 - 3.4e-05 23.0 0.2 4.2 6.2 0.1 4.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EGG22488.1 - 0.00011 20.7 0.0 0.007 14.7 0.0 2.2 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 EGG22488.1 - 0.00024 19.9 3.9 0.015 14.0 0.1 3.0 2 2 0 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EGG22488.1 - 0.002 17.5 0.3 11 5.2 0.0 3.6 2 2 1 3 3 3 1 WD40-like domain Mcl1_mid PF12341.8 EGG22488.1 - 0.012 15.0 0.1 0.051 12.9 0.1 2.0 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region U-box PF04564.15 EGG22488.1 - 0.013 15.7 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 U-box domain Cytochrom_D1 PF02239.16 EGG22488.1 - 0.018 13.6 3.0 0.43 9.0 0.3 2.7 2 1 1 3 3 3 0 Cytochrome D1 heme domain Lum_binding PF00677.17 EGG22488.1 - 0.025 14.5 0.2 0.2 11.7 0.0 2.4 2 1 0 2 2 2 0 Lumazine binding domain zf-Nse PF11789.8 EGG22488.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Apis_Csd PF11671.8 EGG22488.1 - 0.17 11.9 4.1 0.33 11.0 4.1 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein DUF5570 PF17731.1 EGG22488.1 - 0.19 11.8 3.1 0.91 9.6 0.3 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5570) TIG PF01833.24 EGG22489.1 - 1e-56 188.9 245.7 5.4e-07 29.6 6.9 20.1 18 1 1 19 19 19 18 IPT/TIG domain Arm PF00514.23 EGG22489.1 - 5.8e-07 29.3 8.5 0.3 11.2 0.2 4.9 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat TOM13 PF08219.11 EGG22489.1 - 0.1 12.6 2.2 61 3.7 0.1 3.7 3 0 0 3 3 3 0 Outer membrane protein TOM13 Corona_NSP4_C PF16348.5 EGG22489.1 - 0.51 11.2 2.5 35 5.3 0.0 3.9 3 0 0 3 3 3 0 Coronavirus nonstructural protein 4 C-terminus T2SS-T3SS_pil_N PF13629.6 EGG22489.1 - 0.91 9.3 7.9 50 3.7 0.2 4.4 3 0 0 3 3 3 0 Pilus formation protein N terminal region Syntaxin_2 PF14523.6 EGG22490.1 - 4.3e-22 78.4 6.6 4.3e-22 78.4 6.6 2.9 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EGG22490.1 - 6.1e-12 45.4 2.9 2.2e-11 43.5 0.3 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EGG22490.1 - 7.5e-06 25.8 17.6 0.00017 21.4 17.6 2.7 1 1 0 1 1 1 1 Syntaxin RAMP4 PF06624.12 EGG22490.1 - 0.053 13.6 0.9 0.098 12.7 0.0 1.9 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 T2SSF PF00482.23 EGG22490.1 - 0.09 12.7 1.3 4.8 7.2 0.5 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F SAE2 PF08573.10 EGG22490.1 - 0.3 12.2 6.6 1.2 10.3 6.6 2.0 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Neurensin PF14927.6 EGG22490.1 - 0.61 9.8 2.3 1.3 8.7 0.2 2.3 2 0 0 2 2 2 0 Neurensin ALMT PF11744.8 EGG22490.1 - 5.1 5.8 14.3 7.2 5.3 14.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Synaptobrevin PF00957.21 EGG22490.1 - 9.6 6.1 8.3 3.4 7.5 4.6 2.2 2 1 0 2 2 2 0 Synaptobrevin PLAC8 PF04749.17 EGG22491.1 - 6.7e-10 39.9 31.9 2e-09 38.3 31.9 2.2 1 1 0 1 1 1 1 PLAC8 family DHHC PF01529.20 EGG22492.1 - 4.1e-30 104.6 13.8 4.1e-30 104.6 13.8 3.0 3 1 0 3 3 3 1 DHHC palmitoyltransferase Ank_4 PF13637.6 EGG22492.1 - 4.1e-28 97.4 6.9 1.5e-12 47.7 0.1 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG22492.1 - 4.4e-27 94.5 0.1 5.3e-15 55.8 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG22492.1 - 5.7e-23 78.5 0.2 2.2e-05 24.5 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EGG22492.1 - 2.3e-22 78.4 0.1 2.1e-05 24.8 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EGG22492.1 - 2.5e-21 75.5 1.4 2e-09 37.5 0.0 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) IGFBP PF00219.18 EGG22492.1 - 5.2 7.8 7.0 10 6.9 7.0 1.4 1 0 0 1 1 1 0 Insulin-like growth factor binding protein VKG_Carbox PF05090.14 EGG22493.1 - 7.7e-09 34.9 23.1 1.3e-08 34.1 23.1 1.3 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase FYVE PF01363.21 EGG22494.1 - 2.2 8.5 10.4 14 5.9 8.8 2.7 1 1 1 2 2 2 0 FYVE zinc finger Tmemb_170 PF10190.9 EGG22495.1 - 2.6e-18 66.3 6.4 3e-18 66.1 6.4 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 Pkinase PF00069.25 EGG22496.1 - 9.8e-29 100.5 0.5 1.7e-27 96.4 0.5 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG22496.1 - 2e-13 50.2 0.1 3.6e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FNIP PF05725.12 EGG22496.1 - 7.6e-06 26.0 10.5 0.00057 20.0 1.9 4.2 2 1 3 5 5 5 4 FNIP Repeat Kinase-like PF14531.6 EGG22496.1 - 0.0016 17.9 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FNIP PF05725.12 EGG22498.1 - 6e-108 352.8 14.8 1.7e-17 63.3 0.3 7.1 7 0 0 7 7 7 7 FNIP Repeat LRR_5 PF13306.6 EGG22498.1 - 1.1e-07 31.8 0.0 0.0036 17.2 0.1 3.2 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) GCV_T_C PF08669.11 EGG22498.1 - 1.6e-07 31.2 0.0 1.4 8.9 0.0 6.0 2 2 6 8 8 8 2 Glycine cleavage T-protein C-terminal barrel domain Phage_min_tail PF05939.13 EGG22498.1 - 3.6e-06 27.3 20.5 1.2 9.5 0.1 9.3 1 1 8 10 10 10 2 Phage minor tail protein Cdh1_DBD_1 PF18196.1 EGG22498.1 - 0.00076 19.8 0.3 23 5.3 0.0 6.0 2 2 6 9 9 9 0 Chromodomain helicase DNA-binding domain 1 DUF1731 PF08338.11 EGG22498.1 - 0.0058 16.4 0.3 2e+02 1.9 0.0 6.3 8 1 1 9 9 9 0 Domain of unknown function (DUF1731) Tecti-min-caps PF09300.10 EGG22498.1 - 0.029 14.4 6.3 7.7 6.7 0.1 5.4 5 1 1 7 7 7 0 Tectiviridae, minor capsid SHQ1 PF04925.15 EGG22498.1 - 0.038 13.5 1.0 31 4.1 0.0 4.8 2 2 5 7 7 7 0 SHQ1 protein HEAT PF02985.22 EGG22499.1 - 4.8e-45 147.7 27.3 0.008 16.4 0.1 22.8 24 0 0 24 24 23 11 HEAT repeat HEAT_2 PF13646.6 EGG22499.1 - 4.1e-37 126.4 5.3 0.0013 19.1 0.0 15.9 9 4 9 18 18 18 8 HEAT repeats HEAT_EZ PF13513.6 EGG22499.1 - 4.8e-34 116.4 25.5 0.012 16.1 0.0 18.3 16 3 4 20 20 20 9 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGG22499.1 - 2.9e-18 66.2 0.0 0.1 13.2 0.0 10.4 7 2 3 10 10 10 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGG22499.1 - 2.6e-14 53.4 15.3 0.058 12.9 0.0 9.5 8 1 0 9 9 9 4 CLASP N terminal Cnd1 PF12717.7 EGG22499.1 - 4.6e-10 39.8 30.2 0.65 10.0 0.0 13.3 11 6 4 15 15 15 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 EGG22499.1 - 3e-07 29.8 37.6 5.1e-07 29.1 0.0 8.1 10 0 0 10 10 10 3 Interferon-related developmental regulator (IFRD) ParcG PF10274.9 EGG22499.1 - 3.3e-06 27.3 19.7 30 4.6 0.0 11.2 10 3 2 13 13 13 0 Parkin co-regulated protein Arm PF00514.23 EGG22499.1 - 2.2e-05 24.3 9.2 0.064 13.3 0.0 7.9 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat NUC173 PF08161.12 EGG22499.1 - 0.00016 21.4 4.7 1.3 8.7 0.0 5.7 6 0 0 6 6 6 2 NUC173 domain TAF6_C PF07571.13 EGG22499.1 - 0.00048 20.4 3.9 28 5.1 0.0 6.9 6 1 0 6 6 5 0 TAF6 C-terminal HEAT repeat domain Condensin2nSMC PF12422.8 EGG22499.1 - 0.0042 17.3 3.8 95 3.1 0.1 6.9 6 1 1 7 7 7 0 Condensin II non structural maintenance of chromosomes subunit DUF3437 PF11919.8 EGG22499.1 - 0.037 13.9 2.6 39 4.2 0.0 5.7 5 0 0 5 5 5 0 Domain of unknown function (DUF3437) TIP120 PF08623.10 EGG22499.1 - 0.06 13.1 19.5 4.6 7.0 0.0 8.3 10 1 0 10 10 9 0 TATA-binding protein interacting (TIP20) Importin_rep_5 PF18816.1 EGG22499.1 - 5.3 7.4 7.0 14 6.0 0.0 5.1 6 0 0 6 6 5 0 Importin repeat tRNA-synt_2c PF01411.19 EGG22500.1 - 1.1e-206 687.6 1.7 2.8e-205 683.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (A) DHHA1 PF02272.19 EGG22500.1 - 1.6e-19 70.6 1.9 4.7e-19 69.2 1.9 1.8 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 EGG22500.1 - 1.2e-14 54.1 0.0 4.2e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF3857 PF12969.7 EGG22500.1 - 0.066 13.3 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3857) RNase_PH_C PF03725.15 EGG22500.1 - 0.13 12.4 0.0 0.82 9.8 0.0 2.4 2 1 0 2 2 2 0 3' exoribonuclease family, domain 2 PDZ PF00595.24 EGG22500.1 - 0.13 12.6 0.3 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 PDZ domain RNA_pol_Rpb1_1 PF04997.12 EGG22501.1 - 4.9e-91 305.3 1.3 7.5e-91 304.7 1.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EGG22501.1 - 2.9e-90 302.3 0.5 5.2e-90 301.5 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGG22501.1 - 1.6e-73 246.4 0.0 4e-73 245.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGG22501.1 - 8.2e-35 120.1 0.0 3.9e-34 117.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGG22501.1 - 2.4e-32 111.1 0.1 1e-31 109.0 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 zinc_ribbon_10 PF10058.9 EGG22501.1 - 0.013 15.2 4.9 0.37 10.6 0.1 2.9 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein HPS3_N PF14761.6 EGG22502.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 ABC2_membrane PF01061.24 EGG22503.1 - 1.7e-35 122.4 16.2 2.9e-35 121.6 16.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGG22503.1 - 2.5e-07 31.3 0.0 1.9e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGG22503.1 - 0.0065 16.3 0.5 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGG22503.1 - 0.19 10.8 18.0 0.35 9.9 18.0 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-C4H2 PF10146.9 EGG22504.1 - 5.9e-16 59.4 6.4 5.9e-16 59.4 6.4 2.0 2 0 0 2 2 2 1 Zinc finger-containing protein Med14 PF08638.11 EGG22504.1 - 0.0036 16.8 1.3 0.0048 16.3 0.5 1.6 1 1 0 1 1 1 1 Mediator complex subunit MED14 PsbW PF07123.12 EGG22504.1 - 0.5 10.4 2.0 0.88 9.6 0.6 2.0 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) SARAF PF06682.12 EGG22504.1 - 0.63 9.6 3.3 0.18 11.4 0.2 1.5 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Acetate_kinase PF00871.17 EGG22504.1 - 1.5 7.4 5.0 0.21 10.3 1.2 1.4 2 0 0 2 2 2 0 Acetokinase family AMP-binding_C_2 PF14535.6 EGG22504.1 - 2.2 8.6 6.2 0.87 9.9 3.1 2.0 2 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain TMPIT PF07851.13 EGG22504.1 - 2.4 7.3 5.3 3.2 6.9 5.3 1.5 1 0 0 1 1 1 0 TMPIT-like protein Mucin PF01456.17 EGG22504.1 - 7.8 6.5 11.5 11 6.1 6.4 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Ribosomal_S17 PF00366.20 EGG22505.1 - 9.8e-18 64.0 1.3 1.6e-17 63.3 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Orthopox_A49R PF06489.11 EGG22505.1 - 0.13 12.5 0.1 0.16 12.2 0.1 1.3 1 1 0 1 1 1 0 Orthopoxvirus A49R protein RPAP1_C PF08620.10 EGG22506.1 - 1.5e-22 79.5 0.1 3.7e-22 78.2 0.1 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EGG22506.1 - 1e-15 57.2 1.7 1e-15 57.2 1.7 2.5 2 0 0 2 2 2 1 RPAP1-like, N-terminal FA_hydroxylase PF04116.13 EGG22507.1 - 3.6e-27 95.3 15.3 3.6e-27 95.3 15.3 1.8 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily DEAD PF00270.29 EGG22508.1 - 0.053 13.3 0.5 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase NIF PF03031.18 EGG22509.1 - 1.7e-17 63.6 1.2 2.9e-17 62.8 0.2 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EGG22509.1 - 2.8e-09 37.2 0.2 7.2e-09 35.9 0.2 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGG22509.1 - 2.1e-06 27.6 0.1 4e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 EGG22509.1 - 0.003 17.9 0.1 0.0077 16.6 0.1 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Atrophin-1 PF03154.15 EGG22509.1 - 0.071 11.4 8.5 0.099 10.9 8.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family RTT107_BRCT_5 PF16770.5 EGG22509.1 - 0.13 12.1 2.7 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain NAD_binding_4 PF07993.12 EGG22509.1 - 1.9 7.6 4.5 0.47 9.6 1.1 1.7 2 1 0 2 2 2 0 Male sterility protein Macoilin PF09726.9 EGG22511.1 - 2.4 6.6 10.6 3.6 6.0 10.6 1.3 1 0 0 1 1 1 0 Macoilin family Pkinase_Tyr PF07714.17 EGG22512.1 - 8.2e-61 205.5 0.0 1.4e-60 204.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG22512.1 - 1.5e-52 178.6 0.0 3.9e-52 177.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain RGS PF00615.19 EGG22512.1 - 1e-18 67.7 4.2 1e-18 67.7 4.2 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.6 EGG22512.1 - 0.00022 20.7 0.0 0.00022 20.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EGG22512.1 - 0.00081 19.0 0.1 0.025 14.2 0.0 2.5 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 EGG22512.1 - 0.0016 17.9 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG22512.1 - 0.0042 17.0 0.0 0.0042 17.0 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family RNase_Zc3h12a PF11977.8 EGG22514.1 - 3.9e-21 75.5 0.1 1.4e-20 73.7 0.0 1.9 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain LRR_8 PF13855.6 EGG22515.1 - 1.1e-07 31.4 8.4 3.8e-05 23.3 0.1 4.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 EGG22515.1 - 1.2e-05 24.9 4.3 0.31 11.2 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich repeat Mon1 PF03164.14 EGG22516.1 - 1.9e-127 425.7 12.2 2.4e-127 425.4 12.2 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 FAM220 PF15487.6 EGG22516.1 - 0.11 12.1 6.0 0.21 11.2 6.0 1.4 1 0 0 1 1 1 0 FAM220 family Mucin PF01456.17 EGG22516.1 - 0.91 9.5 15.6 1.6 8.7 15.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Menin PF05053.13 EGG22516.1 - 2.7 6.2 11.8 3.9 5.7 11.8 1.1 1 0 0 1 1 1 0 Menin Tubulin PF00091.25 EGG22517.1 - 2.2e-60 204.3 0.0 3.8e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGG22517.1 - 6.6e-39 132.9 0.0 1.1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Complex1_LYR PF05347.15 EGG22517.1 - 1.1e-06 28.5 0.1 2e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Tubulin_3 PF14881.6 EGG22517.1 - 0.00018 21.2 0.0 0.00054 19.7 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain HD PF01966.22 EGG22518.1 - 3e-11 43.6 0.0 5.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 HD domain ChlamPMP_M PF07548.11 EGG22519.1 - 0.0025 17.8 4.9 0.0025 17.8 4.9 4.1 4 1 0 4 4 4 1 Chlamydia polymorphic membrane protein middle domain Insulin_TMD PF17870.1 EGG22519.1 - 0.096 12.8 0.3 2.6 8.2 0.0 2.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment CD99L2 PF12301.8 EGG22519.1 - 0.12 12.6 0.2 0.2 11.9 0.2 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 Amnionless PF14828.6 EGG22519.1 - 0.25 10.1 3.7 4.3 6.0 0.3 2.8 3 0 0 3 3 3 0 Amnionless ChlamPMP_M PF07548.11 EGG22520.1 - 0.0032 17.4 14.8 0.022 14.7 3.1 4.6 4 1 0 4 4 4 2 Chlamydia polymorphic membrane protein middle domain DUF2931 PF11153.8 EGG22520.1 - 0.052 13.3 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2931) Amnionless PF14828.6 EGG22520.1 - 1.6 7.5 4.5 2.3 6.9 0.1 2.6 3 0 0 3 3 3 0 Amnionless Pyr_redox_2 PF07992.14 EGG22521.1 - 9.6e-53 179.3 0.0 3.1e-48 164.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG22521.1 - 6.8e-13 49.0 0.0 5e-10 39.8 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG22521.1 - 0.00073 18.9 0.0 0.15 11.2 0.1 3.5 3 2 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG22521.1 - 0.016 15.4 0.0 5.2 7.4 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Dicty_REP PF05086.12 EGG22521.1 - 0.023 12.7 3.7 0.034 12.2 3.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1199 PF06712.11 EGG22521.1 - 0.079 13.0 1.2 0.7 10.0 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) Mod_r PF07200.13 EGG22521.1 - 0.091 12.9 0.4 0.19 11.8 0.4 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DEAD PF00270.29 EGG22522.1 - 2.3e-45 154.5 0.1 8.4e-45 152.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG22522.1 - 5.4e-28 97.5 0.1 5.4e-28 97.5 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DDHD PF02862.17 EGG22522.1 - 0.0085 16.3 9.4 0.074 13.2 0.3 2.3 2 0 0 2 2 2 2 DDHD domain SID-1_RNA_chan PF13965.6 EGG22522.1 - 2.5 6.4 14.0 2.9 6.2 1.0 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 SDA1 PF05285.12 EGG22522.1 - 6 6.2 45.9 0.43 10.0 28.2 2.1 2 0 0 2 2 2 0 SDA1 DUF5314 PF17241.2 EGG22523.1 - 0.016 14.9 0.1 0.02 14.6 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5314) DEAD PF00270.29 EGG22524.1 - 3.3e-33 114.9 0.1 6.8e-33 113.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG22524.1 - 1e-22 80.6 0.0 2.8e-22 79.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG22524.1 - 0.0011 19.0 0.0 0.0011 19.0 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit SSP160 PF06933.11 EGG22524.1 - 1.9 6.6 9.1 0.3 9.3 4.5 1.7 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EGG22524.1 - 2.1 8.3 12.5 0.11 12.4 5.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein UCMA PF17085.5 EGG22524.1 - 6 6.9 18.6 13 5.8 18.6 1.6 1 0 0 1 1 1 0 Unique cartilage matrix associated protein ROS_MUCR PF05443.11 EGG22525.1 - 0.13 12.3 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Formyl_trans_N PF00551.19 EGG22526.1 - 1.6e-20 73.6 0.0 2.6e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EGG22526.1 - 9.9e-10 38.6 0.2 1.3e-08 35.0 0.2 2.3 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain DUF3598 PF12204.8 EGG22526.1 - 0.019 14.5 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) NEAT PF05031.12 EGG22526.1 - 0.024 15.3 0.8 0.11 13.2 0.1 2.5 2 0 0 2 2 2 0 Iron Transport-associated domain DUF5341 PF17276.2 EGG22526.1 - 0.34 11.1 4.0 1.1 9.4 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5341) ICAT PF06384.11 EGG22527.1 - 5.1e-30 103.6 0.3 5.1e-30 103.6 0.3 2.6 2 0 0 2 2 2 1 Beta-catenin-interacting protein ICAT DUF3430 PF11912.8 EGG22527.1 - 1.4e-25 90.6 16.1 1.4e-25 90.6 16.1 4.1 3 1 0 3 3 3 1 Protein of unknown function (DUF3430) RRM_1 PF00076.22 EGG22527.1 - 1.1e-16 60.4 0.0 2.7e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 EGG22527.1 - 6.9e-05 22.6 2.0 0.00027 20.7 2.0 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGG22527.1 - 0.00016 21.6 2.3 0.00016 21.6 2.3 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGG22527.1 - 0.009 16.3 2.7 0.009 16.3 2.7 3.2 3 0 0 3 3 3 1 Ring finger domain zf-RanBP PF00641.18 EGG22527.1 - 0.91 8.9 3.5 1.6 8.1 0.6 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others C6_DPF PF10170.9 EGG22527.1 - 8.4 6.8 10.6 20 5.7 4.4 3.0 2 0 0 2 2 2 0 Cysteine-rich domain CBM49 PF09478.10 EGG22528.1 - 1.1e-12 48.1 1.1 2.8e-12 46.8 1.1 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM_2 PF00553.19 EGG22528.1 - 0.005 17.1 1.2 0.011 16.1 1.2 1.6 1 0 0 1 1 1 1 Cellulose binding domain UbiA PF01040.18 EGG22528.1 - 0.16 11.2 0.5 0.25 10.6 0.5 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family zf-RVT PF13966.6 EGG22529.1 - 4.9e-05 24.0 0.7 0.00018 22.1 0.7 1.9 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase LuxT_C PF18285.1 EGG22530.1 - 0.037 14.6 0.2 4.7 7.8 0.0 2.8 3 0 0 3 3 3 0 Tetracycline repressor LuxT C-terminal domain Urocanase PF01175.18 EGG22531.1 - 1.6e-86 289.3 0.0 2.3e-86 288.8 0.0 1.2 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_C PF17392.2 EGG22531.1 - 1.5e-83 279.1 2.7 2.3e-83 278.5 2.7 1.3 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase_N PF17391.2 EGG22531.1 - 5.7e-56 187.7 0.2 1.1e-55 186.7 0.2 1.5 1 0 0 1 1 1 1 Urocanase N-terminal domain DUF1181 PF06680.11 EGG22531.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) FNIP PF05725.12 EGG22532.1 - 5e-163 529.1 74.9 4.6e-18 65.1 0.4 12.8 6 1 8 16 16 16 15 FNIP Repeat Pkinase PF00069.25 EGG22532.1 - 1.1e-33 116.8 2.9 2.4e-33 115.6 2.9 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG22532.1 - 1.6e-17 63.6 0.6 1.1e-16 60.9 0.6 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Phage_min_tail PF05939.13 EGG22532.1 - 1.8e-07 31.5 26.8 2 8.8 0.0 11.0 5 3 7 12 12 12 4 Phage minor tail protein bZIP_2 PF07716.15 EGG22532.1 - 0.0015 18.6 17.3 0.0055 16.8 17.3 2.1 1 1 0 1 1 1 1 Basic region leucine zipper Ald_deCOase PF11266.8 EGG22532.1 - 0.0061 16.3 0.0 4.1 7.0 0.0 4.6 3 2 3 6 6 6 1 Long-chain fatty aldehyde decarbonylase bZIP_1 PF00170.21 EGG22532.1 - 0.0063 16.6 16.8 0.0063 16.6 16.8 2.3 2 0 0 2 2 2 1 bZIP transcription factor LBR_tudor PF09465.10 EGG22532.1 - 0.17 11.7 3.2 1.6 8.6 0.8 2.7 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain AAA_23 PF13476.6 EGG22533.1 - 0.02 15.4 34.5 0.076 13.5 14.2 2.5 2 0 0 2 2 2 0 AAA domain TAP_C PF03943.13 EGG22534.1 - 1.1e-13 50.6 0.4 2e-13 49.8 0.4 1.4 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.6 EGG22534.1 - 0.00012 21.9 0.5 0.00025 20.8 0.5 1.6 1 0 0 1 1 1 1 UBA-like domain NTF2 PF02136.20 EGG22534.1 - 0.00018 22.1 0.1 0.00044 20.8 0.1 1.7 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.6 EGG22534.1 - 0.00036 20.1 0.3 0.0011 18.5 0.2 1.8 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EGG22534.1 - 0.8 10.2 5.0 1.3 9.5 0.2 3.0 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) Syntaxin-6_N PF09177.11 EGG22535.1 - 1.9e-20 73.3 3.4 1.9e-20 73.3 3.4 2.2 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EGG22535.1 - 0.0061 16.5 0.3 0.013 15.5 0.3 1.6 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 EGG22535.1 - 0.016 14.9 14.0 0.18 11.5 14.0 2.0 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF3332 PF11810.8 EGG22535.1 - 0.12 12.1 2.7 0.21 11.2 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) DUF16 PF01519.16 EGG22535.1 - 0.53 10.8 10.5 0.28 11.7 5.7 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Noc2 PF03715.13 EGG22536.1 - 2.3e-92 309.5 8.7 2.3e-92 309.5 8.7 3.1 4 0 0 4 4 4 1 Noc2p family Acetyltransf_11 PF13720.6 EGG22536.1 - 0.073 13.5 1.1 5.5 7.5 0.2 3.7 3 1 1 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 YwcE PF17368.2 EGG22536.1 - 0.11 13.2 0.6 0.39 11.4 0.1 2.1 2 0 0 2 2 2 0 Spore morphogenesis and germination YwcE Mg_trans_NIPA PF05653.14 EGG22537.1 - 0.0082 15.3 2.7 0.011 14.9 2.7 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA Babuvirus_MP PF07234.11 EGG22537.1 - 0.013 15.6 3.1 0.02 15.1 3.1 1.4 1 0 0 1 1 1 0 Movement and RNA silencing protein DUF2680 PF10925.8 EGG22542.1 - 0.096 12.7 5.8 0.27 11.3 1.0 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) Nup54 PF13874.6 EGG22542.1 - 0.32 11.1 6.6 0.53 10.4 4.8 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Spc24 PF08286.11 EGG22542.1 - 0.57 10.5 9.7 0.088 13.1 3.7 2.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SlyX PF04102.12 EGG22542.1 - 4.4 8.0 9.3 8.7 7.0 1.2 3.3 2 0 0 2 2 2 0 SlyX CENP-T_N PF16171.5 EGG22543.1 - 0.067 12.1 0.8 0.093 11.6 0.1 1.6 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T N-terminus Ima1_N PF09779.9 EGG22544.1 - 3e-07 31.4 14.0 3e-07 31.4 14.0 2.6 3 0 0 3 3 3 1 Ima1 N-terminal domain Peptidase_M14 PF00246.24 EGG22545.1 - 9.3e-68 229.1 0.1 1.3e-67 228.6 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EGG22545.1 - 3.2e-06 26.4 0.0 9.7e-06 24.9 0.0 1.8 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 EGG22545.1 - 0.0013 18.2 0.2 0.0023 17.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) CarboxypepD_reg PF13620.6 EGG22545.1 - 0.0014 18.9 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EGG22545.1 - 0.0026 17.7 0.1 0.006 16.6 0.1 1.7 1 0 0 1 1 1 1 CarboxypepD_reg-like domain FNIP PF05725.12 EGG22546.1 - 1.9e-46 156.0 19.5 7.1e-12 45.3 0.0 8.9 5 2 0 8 8 8 8 FNIP Repeat HD_4 PF13328.6 EGG22547.1 - 4.5e-21 75.2 0.0 6e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.22 EGG22547.1 - 0.0059 16.8 0.1 0.014 15.6 0.1 1.7 1 1 0 1 1 1 1 HD domain Ku_N PF03731.15 EGG22548.1 - 2.4e-48 164.8 2.0 2.4e-48 164.8 2.0 2.2 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 EGG22548.1 - 5.3e-40 137.3 0.2 1.2e-39 136.1 0.2 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain zf-CCHH PF10283.9 EGG22548.1 - 4.8e-13 48.8 3.8 8.1e-13 48.1 3.8 1.4 1 0 0 1 1 1 1 PBZ domain Ku_C PF03730.14 EGG22548.1 - 2.8e-11 44.0 0.1 2.8e-11 44.0 0.1 2.7 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm HeH PF12949.7 EGG22548.1 - 0.015 15.0 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 HeH/LEM domain T2SSC PF11356.8 EGG22548.1 - 0.051 13.5 0.4 0.68 9.8 1.4 2.2 2 0 0 2 2 2 0 Type II secretion system protein C DUF848 PF05852.11 EGG22548.1 - 0.12 12.5 0.8 0.29 11.3 0.8 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF908 PF06012.12 EGG22548.1 - 4.8 6.5 12.2 8.9 5.6 12.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Mucin PF01456.17 EGG22548.1 - 6.3 6.8 21.6 13 5.8 14.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein MRP-L28 PF09812.9 EGG22549.1 - 0.0016 18.6 5.9 0.0016 18.6 5.9 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L28 L51_S25_CI-B8 PF05047.16 EGG22550.1 - 6.4e-11 42.0 0.1 1.1e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Pribosyltran_N PF13793.6 EGG22551.1 - 6.6e-37 126.0 1.6 1.1e-35 122.1 0.2 2.6 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGG22551.1 - 9.3e-33 113.8 6.0 1.3e-31 110.1 2.8 3.0 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGG22551.1 - 1.1e-11 44.5 1.3 2.9e-11 43.2 1.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain RRM_1 PF00076.22 EGG22552.1 - 1.1e-07 31.6 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lipoprotein_19 PF13617.6 EGG22552.1 - 0.0029 17.4 3.5 0.86 9.4 0.2 2.9 2 0 0 2 2 2 2 YnbE-like lipoprotein RRM_1 PF00076.22 EGG22553.1 - 4.8e-14 51.9 0.0 1.2e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dicty_REP PF05086.12 EGG22553.1 - 0.24 9.3 7.3 0.34 8.9 7.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SUR7 PF06687.12 EGG22554.1 - 0.0021 17.7 7.4 0.0021 17.7 7.4 2.9 2 1 1 3 3 3 1 SUR7/PalI family Vut_1 PF02592.15 EGG22554.1 - 0.0066 16.8 8.4 0.0066 16.8 8.4 2.2 2 1 0 2 2 2 1 Putative vitamin uptake transporter DUF4064 PF13273.6 EGG22554.1 - 0.075 13.3 13.7 0.53 10.6 4.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Amastin PF07344.11 EGG22554.1 - 0.1 12.5 6.6 0.19 11.6 5.6 1.9 1 1 0 1 1 1 0 Amastin surface glycoprotein TctB PF07331.11 EGG22554.1 - 0.54 10.5 11.4 1.9 8.7 7.5 2.4 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF202 PF02656.15 EGG22554.1 - 1.2 9.6 8.4 0.91 10.0 0.8 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF485 PF04341.12 EGG22554.1 - 1.4 8.9 6.5 0.3 11.1 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DUF1218 PF06749.12 EGG22554.1 - 1.9 9.1 11.2 1.6 9.3 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) 2TM PF13239.6 EGG22554.1 - 3.7 7.9 11.8 0.2 12.0 3.2 2.9 2 1 1 3 3 3 0 2TM domain SLATT_fungal PF18142.1 EGG22554.1 - 8.3 6.4 6.4 0.59 10.1 1.4 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Ras PF00071.22 EGG22555.1 - 3.7e-60 202.2 0.1 4.2e-60 202.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG22555.1 - 1.4e-33 115.6 0.0 5.2e-33 113.8 0.0 1.7 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG22555.1 - 5.9e-11 42.1 0.1 7.3e-11 41.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG22555.1 - 6.2e-05 22.5 0.0 8.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGG22555.1 - 0.0002 21.3 0.1 0.14 12.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGG22555.1 - 0.00049 20.2 0.0 0.001 19.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG22555.1 - 0.0014 18.2 0.0 0.0029 17.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGG22555.1 - 0.019 15.3 0.1 0.037 14.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 EGG22556.1 - 4.8e-63 212.5 54.9 7.6e-38 130.2 1.8 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGG22556.1 - 1.7e-27 96.1 0.0 8.8e-27 93.7 0.0 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGG22556.1 - 6e-11 42.7 7.2 4.7e-06 26.6 0.0 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGG22556.1 - 8.7e-06 25.4 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CENP-F_leu_zip PF10473.9 EGG22556.1 - 0.00069 19.6 22.3 0.00069 19.6 22.3 9.4 5 2 4 9 9 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.11 EGG22556.1 - 0.0016 17.4 9.4 0.0016 17.4 9.4 6.2 4 2 2 6 6 6 4 Protein of unknown function (DUF812) TMF_TATA_bd PF12325.8 EGG22556.1 - 0.0036 17.5 4.5 0.0036 17.5 4.5 10.7 5 2 4 10 10 10 1 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 EGG22556.1 - 0.13 12.6 0.0 0.13 12.6 0.0 11.1 9 4 4 13 13 13 0 Flagella accessory protein C (FlaC) Arf PF00025.21 EGG22557.1 - 4.3e-69 231.5 0.1 4.8e-69 231.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG22557.1 - 2.5e-16 60.0 0.0 3.5e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG22557.1 - 4.4e-13 49.1 0.0 4.9e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGG22557.1 - 5.5e-12 45.5 0.0 6.9e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGG22557.1 - 9.9e-11 41.4 0.6 4e-08 32.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGG22557.1 - 2.5e-07 30.3 0.0 3.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG22557.1 - 3.3e-05 23.9 0.0 5.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG22557.1 - 0.008 15.7 0.2 0.06 12.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EGG22557.1 - 0.066 13.4 0.1 0.28 11.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain SRP54 PF00448.22 EGG22557.1 - 0.18 11.4 0.4 7 6.2 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Arf PF00025.21 EGG22559.1 - 1.7e-53 180.7 0.2 2e-53 180.5 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGG22559.1 - 1.1e-09 38.1 0.0 1.2e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG22559.1 - 6.2e-09 36.1 0.0 9.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGG22559.1 - 4.8e-08 32.6 0.1 0.0025 17.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGG22559.1 - 2.3e-07 30.4 0.0 3.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGG22559.1 - 3.2e-06 26.7 0.0 5.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGG22559.1 - 0.0035 17.4 0.0 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG22559.1 - 0.0083 15.7 0.1 0.046 13.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NOG1 PF06858.14 EGG22559.1 - 0.14 11.9 0.1 2.4 8.0 0.1 2.4 1 1 1 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) cobW PF02492.19 EGG22559.1 - 0.3 10.7 3.1 1.6 8.2 0.6 2.1 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain EMP24_GP25L PF01105.24 EGG22561.1 - 1.1e-48 165.6 3.9 1.5e-48 165.2 3.9 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kelch_4 PF13418.6 EGG22562.1 - 3.9e-18 65.2 0.1 5e-06 26.4 0.0 4.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG22562.1 - 2.9e-17 62.2 0.7 1e-05 25.4 0.1 4.0 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 EGG22562.1 - 3.9e-09 36.6 13.2 0.00082 19.6 0.0 6.5 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EGG22562.1 - 7.4e-07 29.2 1.2 0.19 12.1 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 EGG22562.1 - 1.1e-05 25.1 0.2 1.1 9.4 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 EGG22562.1 - 3.4e-05 23.3 0.9 1.3 8.6 0.0 4.0 4 0 0 4 4 4 2 Kelch motif SMAP PF15477.6 EGG22562.1 - 0.081 13.9 0.1 0.15 13.0 0.1 1.5 1 0 0 1 1 1 0 Small acidic protein family BES1_N PF05687.13 EGG22562.1 - 1.6 9.1 0.0 1.6 9.1 0.0 3.0 3 1 0 3 3 3 0 BES1/BZR1 plant transcription factor, N-terminal Macoilin PF09726.9 EGG22562.1 - 8.4 4.8 9.1 11 4.5 9.1 1.1 1 0 0 1 1 1 0 Macoilin family RED_N PF07808.13 EGG22563.1 - 2.4e-19 69.8 6.3 2.4e-19 69.8 6.3 3.7 2 2 2 4 4 4 2 RED-like protein N-terminal region Lsm_interact PF05391.11 EGG22563.1 - 1.9 8.1 10.1 0.047 13.2 2.0 2.6 2 0 0 2 2 2 0 Lsm interaction motif Arf PF00025.21 EGG22564.1 - 4.9e-54 182.4 0.2 5.7e-54 182.2 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGG22564.1 - 8.7e-10 38.4 0.0 9.8e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG22564.1 - 7.6e-09 35.8 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGG22564.1 - 5.2e-08 32.4 0.1 0.0022 17.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGG22564.1 - 2.5e-07 30.3 0.0 3.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGG22564.1 - 2.7e-06 27.0 0.0 4.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGG22564.1 - 0.0038 17.3 0.0 0.0074 16.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG22564.1 - 0.012 15.2 0.0 0.057 12.9 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 EGG22564.1 - 0.42 10.2 2.9 2.6 7.6 0.4 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain WD40 PF00400.32 EGG22565.1 - 6.1e-28 96.5 26.1 0.0001 23.0 0.0 10.6 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG22565.1 - 4.8e-18 65.2 1.9 1.1e-05 25.6 0.0 5.8 4 1 0 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain MYO10_CC PF16735.5 EGG22566.1 - 0.014 15.5 0.4 0.25 11.5 0.0 2.5 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain PRK PF00485.18 EGG22568.1 - 1.3e-18 67.5 0.3 5.8e-17 62.1 0.3 2.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CYTH PF01928.21 EGG22568.1 - 7.6e-14 52.0 0.0 1.3e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 CYTH domain TsaE PF02367.17 EGG22568.1 - 0.0032 17.5 1.3 2 8.4 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EGG22568.1 - 0.021 14.0 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 EGG22568.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 EGG22568.1 - 0.065 12.9 0.4 0.14 11.8 0.2 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_18 PF13238.6 EGG22568.1 - 0.082 13.5 0.1 0.2 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGG22568.1 - 0.13 12.8 0.2 0.44 11.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter CTP_transf_like PF01467.26 EGG22569.1 - 1.2e-19 70.9 0.0 1.7e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like TM2 PF05154.16 EGG22570.1 - 1.1e-21 76.9 11.0 1.4e-21 76.5 11.0 1.1 1 0 0 1 1 1 1 TM2 domain WRW PF10206.9 EGG22570.1 - 3.2 8.2 6.8 8.6 6.8 2.4 2.3 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f CBS PF00571.28 EGG22571.1 - 1.4e-29 102.3 1.6 3.7e-09 36.9 0.0 4.3 4 0 0 4 4 4 4 CBS domain Yos1 PF08571.10 EGG22572.1 - 7.6e-20 71.0 0.4 8.7e-20 70.8 0.4 1.0 1 0 0 1 1 1 1 Yos1-like AAA_33 PF13671.6 EGG22573.1 - 2.8e-10 40.5 0.4 1.1e-08 35.4 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EGG22573.1 - 0.0039 17.4 0.0 0.018 15.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG22573.1 - 0.025 15.0 2.9 0.042 14.2 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain Lzipper-MIP1 PF14389.6 EGG22573.1 - 0.025 14.8 0.1 0.025 14.8 0.1 7.2 5 3 2 7 7 7 0 Leucine-zipper of ternary complex factor MIP1 GDP_Man_Dehyd PF16363.5 EGG22574.1 - 2.3e-59 201.4 0.0 2.9e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG22574.1 - 1.5e-52 178.5 0.0 1.9e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGG22574.1 - 3.8e-15 55.8 0.0 3.3e-14 52.7 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGG22574.1 - 1.6e-14 53.6 0.1 4.4e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGG22574.1 - 2.5e-09 36.6 0.0 4.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EGG22574.1 - 2.9e-09 37.1 0.0 5.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EGG22574.1 - 3.2e-06 26.7 0.0 5.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EGG22574.1 - 0.00078 18.7 0.0 0.016 14.4 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EGG22574.1 - 0.005 16.4 0.0 3.5 7.1 0.0 2.4 2 0 0 2 2 2 2 NmrA-like family Arf PF00025.21 EGG22575.1 - 1.4e-68 229.7 0.1 1.6e-68 229.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG22575.1 - 3.9e-16 59.3 0.0 5.5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG22575.1 - 8.6e-13 48.2 0.0 9.5e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGG22575.1 - 1.7e-11 43.9 0.0 2.1e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGG22575.1 - 6.6e-11 42.0 0.8 2.4e-08 33.5 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGG22575.1 - 9.4e-08 31.7 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG22575.1 - 2.8e-05 24.2 0.0 4.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG22575.1 - 0.021 14.4 0.3 0.15 11.5 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EGG22575.1 - 0.075 13.2 0.1 0.18 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGG22575.1 - 0.2 11.3 0.6 7 6.2 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Dickkopf_N PF04706.12 EGG22576.1 - 0.00019 21.8 25.1 0.00029 21.2 16.2 6.5 3 2 3 6 6 6 3 Dickkopf N-terminal cysteine-rich region Sad1_UNC PF07738.13 EGG22577.1 - 5.3e-31 107.4 0.1 2.2e-30 105.3 0.0 2.1 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Phasin PF05597.11 EGG22577.1 - 0.024 14.6 0.9 0.024 14.6 0.9 2.6 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NAD_Gly3P_dh_N PF01210.23 EGG22577.1 - 0.068 13.1 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Orf78 PF06024.12 EGG22577.1 - 0.29 11.5 2.3 0.98 9.8 0.1 2.9 2 0 0 2 2 2 0 Orf78 (ac78) DUF2252 PF10009.9 EGG22577.1 - 5.9 5.8 10.5 0.77 8.7 1.0 2.5 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2252) K_channel_TID PF07941.11 EGG22577.1 - 9.3 6.8 10.1 4.6 7.8 7.6 1.8 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Ssu72 PF04722.13 EGG22578.1 - 3.8e-10 39.7 0.0 4.1e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Peptidase_M24 PF00557.24 EGG22579.1 - 6.4e-37 127.3 0.0 9.5e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rho_GDI PF02115.17 EGG22580.1 - 6.3e-56 189.2 0.2 7e-56 189.1 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor DUF4249 PF14054.6 EGG22580.1 - 0.02 14.6 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) Usp PF00582.26 EGG22581.1 - 0.022 15.3 0.0 0.14 12.7 0.0 2.1 1 1 0 1 1 1 0 Universal stress protein family D123 PF07065.14 EGG22582.1 - 7.4e-96 320.9 25.9 2.2e-95 319.3 25.9 1.6 1 1 0 1 1 1 1 D123 R2K_2 PF18299.1 EGG22582.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 FRQ PF09421.10 EGG22582.1 - 0.0086 14.2 7.2 0.014 13.5 7.2 1.3 1 0 0 1 1 1 1 Frequency clock protein NOA36 PF06524.12 EGG22582.1 - 0.0093 15.3 14.5 0.0093 15.3 14.5 2.0 2 0 0 2 2 2 1 NOA36 protein RNA12 PF10443.9 EGG22582.1 - 0.14 10.9 8.7 0.048 12.4 4.2 2.0 2 0 0 2 2 2 0 RNA12 protein BSMAP PF12280.8 EGG22582.1 - 0.18 12.0 8.8 0.14 12.4 1.6 2.4 2 1 0 2 2 2 0 Brain specific membrane anchored protein YL1 PF05764.13 EGG22582.1 - 0.35 10.9 17.9 0.019 15.1 10.5 2.0 2 0 0 2 2 2 0 YL1 nuclear protein EIIBC-GUT_N PF03612.14 EGG22582.1 - 0.9 9.3 3.6 1.6 8.4 1.0 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus RNA_pol_Rpc4 PF05132.14 EGG22582.1 - 2.5 8.5 8.4 17 5.8 5.7 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Corazonin PF17308.2 EGG22582.1 - 5.9 7.3 20.3 1 9.7 3.5 3.3 3 0 0 3 3 3 0 Pro-corazonin His_Phos_2 PF00328.22 EGG22583.1 - 2.2e-21 76.6 0.6 1.7e-19 70.5 0.6 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Proteasome PF00227.26 EGG22584.1 - 1.9e-54 184.1 0.0 2.7e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGG22584.1 - 5.9e-12 45.0 0.1 9.8e-12 44.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature FNIP PF05725.12 EGG22585.1 - 2.5e-16 59.5 17.3 2.4e-08 34.0 0.2 7.6 7 1 1 8 8 8 3 FNIP Repeat DUF4899 PF16240.5 EGG22585.1 - 0.025 13.8 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) SAS-6_N PF16531.5 EGG22585.1 - 0.064 13.8 0.1 0.2 12.2 0.1 1.8 1 0 0 1 1 1 0 Centriolar protein SAS N-terminal Methyltransf_17 PF12692.7 EGG22585.1 - 0.072 13.1 0.0 0.27 11.2 0.0 1.9 1 1 1 2 2 2 0 S-adenosyl-L-methionine methyltransferase TIG PF01833.24 EGG22586.1 - 1.6e-15 56.9 53.7 3.8e-05 23.7 5.3 7.3 6 1 0 6 6 6 5 IPT/TIG domain EGF_2 PF07974.13 EGG22586.1 - 0.00077 19.8 11.5 0.0016 18.7 11.5 1.6 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 EGG22586.1 - 0.0024 18.0 5.4 0.006 16.7 5.4 1.6 1 0 0 1 1 1 1 Laminin EGF domain EGF_Tenascin PF18720.1 EGG22586.1 - 0.29 11.2 10.4 0.66 10.1 10.4 1.7 1 0 0 1 1 1 0 Tenascin EGF domain Ribosomal_L37 PF08561.10 EGG22587.1 - 0.039 14.5 7.5 0.14 12.6 3.6 2.6 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L37 Rv2175c_C PF18367.1 EGG22587.1 - 0.14 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Rv2175c C-terminal domain of unknown function PP1_bind PF15276.6 EGG22587.1 - 1.4 9.3 6.2 9.8 6.6 0.2 2.8 3 0 0 3 3 3 0 Protein phosphatase 1 binding Ldh_1_N PF00056.23 EGG22588.1 - 6.7e-36 123.5 0.9 1e-35 122.9 0.9 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EGG22588.1 - 1.3e-33 116.3 0.0 1.8e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_3_C PF01915.22 EGG22588.1 - 0.069 13.1 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain bVLRF1 PF18826.1 EGG22589.1 - 3.2e-51 173.1 2.2 5e-50 169.2 0.0 3.0 2 1 1 3 3 3 1 bacteroidetes VLRF1 release factor Ank_2 PF12796.7 EGG22589.1 - 4.4e-13 49.6 0.2 2e-08 34.7 0.0 2.5 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) VATC PF18716.1 EGG22589.1 - 5.1e-09 35.8 1.2 8.9e-09 35.1 0.1 2.1 2 0 0 2 2 2 1 Vms1-associating treble clef domain Ank_5 PF13857.6 EGG22589.1 - 3.1e-08 33.7 0.0 0.00015 22.0 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22589.1 - 3.2e-08 33.2 0.1 0.022 15.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EGG22589.1 - 0.00019 21.9 0.0 0.49 11.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Eapp_C PF10238.9 EGG22589.1 - 0.0016 18.5 4.2 0.0016 18.5 4.2 3.9 4 1 0 4 4 4 1 E2F-associated phosphoprotein Ank PF00023.30 EGG22589.1 - 0.0026 18.1 0.2 5.2 7.7 0.0 2.8 3 0 0 3 3 2 2 Ankyrin repeat zf-HIT PF04438.16 EGG22589.1 - 0.064 13.1 1.6 0.16 11.8 0.3 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-MYND PF01753.18 EGG22589.1 - 0.1 12.7 2.0 0.22 11.7 0.1 2.4 2 0 0 2 2 2 0 MYND finger zf-met PF12874.7 EGG22589.1 - 0.14 12.6 4.4 0.13 12.7 1.7 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EGG22589.1 - 2.6 8.7 5.1 5.3 7.7 2.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3959 PF13105.6 EGG22589.1 - 7.6 6.0 5.8 20 4.6 5.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Evr1_Alr PF04777.13 EGG22590.1 - 5.1e-27 94.3 0.9 5.1e-27 94.3 0.9 2.0 2 1 0 2 2 2 1 Erv1 / Alr family Cir_N PF10197.9 EGG22591.1 - 1.3e-10 41.2 3.2 1.3e-10 41.2 3.2 4.5 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR RNA_polI_A34 PF08208.11 EGG22591.1 - 7.5e-05 22.9 13.1 7.5e-05 22.9 13.1 2.2 1 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.9 EGG22591.1 - 0.34 10.5 30.3 0.033 13.8 21.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-CCHC_2 PF13696.6 EGG22591.1 - 0.65 9.9 4.7 1.5 8.8 4.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4042 PF13251.6 EGG22592.1 - 2.5e-31 108.8 1.4 4.8e-27 94.8 1.2 4.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4042) HEAT PF02985.22 EGG22592.1 - 1.7e-14 52.6 4.9 0.22 11.9 0.0 8.6 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 EGG22592.1 - 1.1e-10 41.7 0.0 1.4 9.5 0.0 7.3 5 1 2 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 EGG22592.1 - 3.8e-09 36.8 0.0 0.047 14.1 0.0 5.8 6 1 1 7 7 7 3 HEAT repeats Arm PF00514.23 EGG22592.1 - 0.0068 16.4 12.4 4.7 7.4 0.4 7.0 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EGG22592.1 - 0.0071 16.5 0.6 9.5 6.5 0.1 4.6 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DNase_II PF03265.15 EGG22593.1 - 0.0024 17.2 0.3 0.0024 17.2 0.3 1.8 2 0 0 2 2 2 1 Deoxyribonuclease II DNase_II PF03265.15 EGG22594.1 - 0.0001 21.7 3.2 0.00036 19.9 0.0 2.7 3 0 0 3 3 3 1 Deoxyribonuclease II Dicty_REP PF05086.12 EGG22594.1 - 0.11 10.5 10.4 0.15 10.0 10.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TRAUB PF08164.12 EGG22594.1 - 0.22 12.0 0.6 0.72 10.4 0.3 2.0 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal FSA_C PF10479.9 EGG22594.1 - 0.59 8.2 6.3 0.91 7.6 6.3 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF4746 PF15928.5 EGG22594.1 - 0.91 8.9 5.2 0.14 11.6 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Mucin PF01456.17 EGG22594.1 - 3.4 7.7 27.0 5.9 6.9 27.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 EGG22594.1 - 8.8 4.4 17.5 13 3.9 17.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 EP400_N PF15790.5 EGG22595.1 - 4.6 6.0 4.1 5.8 5.6 4.1 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal Arf PF00025.21 EGG22597.1 - 4.8e-61 205.2 0.0 5.3e-61 205.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGG22597.1 - 6.9e-12 45.2 0.1 1.3e-08 34.5 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EGG22597.1 - 2.3e-09 37.5 0.0 4.7e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGG22597.1 - 6.4e-08 32.2 0.0 8.2e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGG22597.1 - 8.5e-08 32.0 0.0 1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGG22597.1 - 3.3e-06 27.1 0.0 9.8e-06 25.6 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGG22597.1 - 6.2e-05 22.5 0.0 7.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GldM_C PF12080.8 EGG22597.1 - 0.1 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 GldM C-terminal domain PduV-EutP PF10662.9 EGG22597.1 - 0.21 11.3 0.0 0.47 10.2 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EGG22597.1 - 0.23 11.0 0.0 10 5.6 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Actin PF00022.19 EGG22598.1 - 1.9e-114 382.4 0.0 1.5e-113 379.5 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGG22598.1 - 1.4e-05 24.1 0.0 3e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 MreB/Mbl protein SPRY PF00622.28 EGG22599.1 - 1.3e-10 41.4 0.6 2.4e-09 37.3 0.3 2.9 2 1 0 2 2 2 1 SPRY domain zf-RING_2 PF13639.6 EGG22599.1 - 2.2e-08 34.3 4.4 2.2e-08 34.3 4.4 3.6 2 1 2 4 4 4 1 Ring finger domain zf-Di19 PF05605.12 EGG22599.1 - 1.3e-07 31.8 6.0 1.3e-07 31.8 6.0 3.7 4 0 0 4 4 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_2 PF13923.6 EGG22599.1 - 6.4e-07 29.1 3.9 6.4e-07 29.1 3.9 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGG22599.1 - 6.3e-06 25.8 3.9 1.8e-05 24.3 3.9 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EGG22599.1 - 0.0065 16.7 3.6 0.0065 16.7 3.6 3.5 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING-like PF08746.11 EGG22599.1 - 0.0068 16.7 2.7 0.0068 16.7 2.7 2.9 3 0 0 3 3 3 1 RING-like domain FOXP-CC PF16159.5 EGG22599.1 - 0.16 12.6 2.3 0.76 10.5 2.3 2.1 1 1 0 1 1 1 0 FOXP coiled-coil domain SOG2 PF10428.9 EGG22599.1 - 0.2 10.9 25.7 0.021 14.1 11.1 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein zf-C2H2_9 PF16293.5 EGG22599.1 - 0.46 10.4 5.7 8.4 6.3 0.1 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-Mss51 PF13824.6 EGG22599.1 - 0.87 9.7 4.5 12 6.1 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 IBR PF01485.21 EGG22599.1 - 0.9 9.8 6.3 0.19 12.0 1.0 2.6 3 0 0 3 3 2 0 IBR domain, a half RING-finger domain Rad50_zn_hook PF04423.14 EGG22599.1 - 0.96 9.3 10.5 9 6.2 0.1 3.7 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-RING_5 PF14634.6 EGG22599.1 - 1.7 8.7 13.0 0.46 10.5 3.2 3.5 3 0 0 3 3 3 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EGG22599.1 - 4.9 7.1 16.8 0.14 12.0 3.5 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Metallophos PF00149.28 EGG22600.1 - 4.4e-41 141.6 0.1 5.7e-41 141.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EGG22600.1 - 0.03 14.0 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 EGG22600.1 - 0.084 13.3 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain TAD2 PF18521.1 EGG22600.1 - 0.36 10.9 1.9 0.78 9.8 1.9 1.5 1 0 0 1 1 1 0 Transactivation domain 2 CLU PF13236.6 EGG22601.1 - 2.2e-62 210.8 0.1 1.8e-61 207.8 0.0 2.5 3 0 0 3 3 3 1 Clustered mitochondria TPR_17 PF13431.6 EGG22601.1 - 1.9e-08 34.1 1.2 0.056 13.8 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat eIF3_p135 PF12807.7 EGG22601.1 - 1e-07 32.2 2.6 1.1e-07 32.0 0.0 2.4 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_2 PF07719.17 EGG22601.1 - 2.4e-05 24.1 0.5 0.015 15.4 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG22601.1 - 0.0003 20.8 0.1 0.0017 18.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG22601.1 - 0.0011 18.7 0.2 0.25 11.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG22601.1 - 0.0011 19.6 0.0 0.053 14.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG22601.1 - 0.0028 17.9 0.2 0.44 10.9 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG22601.1 - 0.0044 17.0 0.3 0.066 13.3 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG22601.1 - 0.01 16.4 0.0 3.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGG22601.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 TPR repeat DUF1754 PF08555.10 EGG22603.1 - 1.1e-10 42.1 18.8 1.1e-10 42.1 18.8 1.7 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) CAF-1_p150 PF11600.8 EGG22603.1 - 0.1 12.3 23.6 0.13 12.0 23.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ORC6 PF05460.13 EGG22603.1 - 0.25 10.6 11.5 0.28 10.4 11.5 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AC_N PF16214.5 EGG22603.1 - 0.93 8.6 3.4 1.1 8.4 3.4 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region RR_TM4-6 PF06459.12 EGG22603.1 - 0.95 9.2 17.1 1.1 9.0 17.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PP2C_C PF07830.13 EGG22603.1 - 2 9.0 7.6 0.17 12.4 2.3 1.9 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Pinin_SDK_memA PF04696.13 EGG22603.1 - 2.3 8.3 24.9 3 7.9 24.9 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region CSG2 PF16965.5 EGG22603.1 - 3.7 6.4 6.0 4.2 6.2 6.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4407 PF14362.6 EGG22603.1 - 5.6 6.2 5.7 6.6 6.0 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DNA_binding_1 PF01035.20 EGG22604.1 - 1e-08 35.2 0.0 2.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Peptidase_S9 PF00326.21 EGG22604.1 - 1.7e-06 27.6 0.1 3.5e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Methyltransf_1N PF02870.15 EGG22604.1 - 0.0049 17.7 0.0 0.016 16.0 0.0 2.0 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Abhydrolase_6 PF12697.7 EGG22604.1 - 0.0081 16.8 0.0 0.019 15.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG22604.1 - 0.22 10.7 0.2 1.6 7.9 0.2 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 CorA PF01544.18 EGG22605.1 - 4.5e-37 127.9 1.2 4.5e-37 127.9 1.2 2.1 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein DUF3149 PF11346.8 EGG22605.1 - 0.0055 16.3 0.5 0.0055 16.3 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3149) RNase_T PF00929.24 EGG22606.1 - 2.5e-10 41.2 0.1 6.5e-07 30.0 0.0 2.7 2 0 0 2 2 2 2 Exonuclease CDP-OH_P_transf PF01066.21 EGG22607.1 - 1.6e-16 60.8 0.1 1.6e-16 60.8 0.1 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DCB PF16213.5 EGG22607.1 - 0.13 12.0 4.1 0.043 13.5 1.2 1.7 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 adh_short PF00106.25 EGG22609.1 - 8.4e-58 195.1 0.6 1.1e-57 194.6 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG22609.1 - 6.8e-39 133.8 0.0 7.9e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG22609.1 - 6.3e-17 62.1 0.1 9.9e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGG22609.1 - 8.3e-05 21.9 0.9 0.00014 21.2 0.9 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EGG22609.1 - 0.00017 21.9 0.1 0.00035 20.8 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 EGG22609.1 - 0.0016 17.9 0.1 0.0031 16.9 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EGG22609.1 - 0.0035 16.9 0.2 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 EGG22609.1 - 0.0045 16.5 0.1 0.011 15.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EGG22609.1 - 0.0078 16.8 0.2 0.094 13.3 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGG22609.1 - 0.02 14.9 1.7 0.069 13.2 0.3 2.4 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF759 PF05537.11 EGG22609.1 - 0.024 13.6 0.3 0.034 13.0 0.3 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) 2-Hacid_dh_C PF02826.19 EGG22609.1 - 0.031 13.7 0.1 0.048 13.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EGG22609.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding HAD_SAK_1 PF10307.9 EGG22610.1 - 3.9e-47 160.7 0.0 7.7e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Rep_3 PF01051.21 EGG22610.1 - 0.02 14.7 1.4 4.6 7.0 0.2 3.3 2 1 1 3 3 3 0 Initiator Replication protein FlbD PF06289.11 EGG22610.1 - 0.03 13.9 0.1 0.1 12.2 0.1 1.8 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins DUF4656 PF15551.6 EGG22610.1 - 0.052 13.1 0.4 0.052 13.1 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4656) zf_CCCH_4 PF18345.1 EGG22612.1 - 3.2e-08 33.4 29.7 0.001 19.1 6.9 4.5 4 1 0 4 4 4 3 Zinc finger domain zf-CCCH PF00642.24 EGG22612.1 - 1.5e-07 31.2 18.0 0.001 18.9 5.2 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EGG22612.1 - 4.5e-06 26.8 16.9 1.5e-05 25.2 10.4 3.0 1 1 1 2 2 2 1 Zinc-finger containing family Torus PF16131.5 EGG22612.1 - 9.2e-06 26.3 30.0 0.0022 18.6 3.5 4.7 3 1 3 6 6 6 3 Torus domain zf-C3H1 PF10650.9 EGG22612.1 - 0.00082 19.0 14.7 0.022 14.5 0.5 3.7 4 0 0 4 4 4 3 Putative zinc-finger domain zf-CCCH_4 PF18044.1 EGG22612.1 - 0.89 9.4 29.4 0.032 14.0 8.0 3.8 4 0 0 4 4 4 0 CCCH-type zinc finger SAP PF02037.27 EGG22613.1 - 4.7e-08 32.6 0.1 1.8e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 SAP domain DUF4611 PF15387.6 EGG22613.1 - 0.011 15.9 3.3 0.011 15.9 3.3 4.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4611) DUF835 PF05763.12 EGG22613.1 - 0.016 14.9 0.5 0.056 13.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF835) Rad21_Rec8 PF04824.16 EGG22613.1 - 0.087 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Spt20 PF12090.8 EGG22613.1 - 0.14 11.7 23.2 0.031 13.9 6.8 2.4 2 0 0 2 2 2 0 Spt20 family RP-C_C PF11800.8 EGG22613.1 - 3.7 7.6 20.4 8.3 6.4 11.6 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region Macoilin PF09726.9 EGG22613.1 - 6.2 5.2 32.5 0.09 11.3 16.5 2.1 2 0 0 2 2 2 0 Macoilin family Thioredox_DsbH PF03190.15 EGG22614.1 - 5.3e-71 237.8 0.0 1e-70 236.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EGG22614.1 - 6.8e-09 35.8 0.0 1.5e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.13 EGG22614.1 - 2.9e-05 23.7 0.1 0.0018 17.8 0.0 2.6 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 EGG22614.1 - 0.004 16.3 0.6 0.097 11.7 0.1 2.3 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Ribosomal_L28e PF01778.17 EGG22614.1 - 2.3 9.0 8.0 6 7.7 8.0 1.6 1 0 0 1 1 1 0 Ribosomal L28e protein family HEAT PF02985.22 EGG22616.1 - 3e-12 45.7 1.6 0.49 10.8 0.2 7.6 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 EGG22616.1 - 0.00012 22.3 0.1 43 4.6 0.0 6.5 5 1 1 6 6 6 0 HEAT repeats Vac14_Fab1_bd PF12755.7 EGG22616.1 - 0.00015 22.3 1.1 0.88 10.2 0.0 4.8 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGG22616.1 - 0.0042 17.5 0.2 1.4e+02 3.1 0.0 6.2 8 0 0 8 8 8 0 HEAT-like repeat RICTOR_N PF14664.6 EGG22616.1 - 0.01 14.8 0.9 0.062 12.3 0.1 2.5 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term MMS19_N PF14500.6 EGG22616.1 - 0.019 14.6 2.0 19 4.7 0.1 4.7 4 2 2 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 EGG22616.1 - 0.026 14.7 0.8 10 6.4 0.0 4.5 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Noc2 PF03715.13 EGG22616.1 - 0.032 13.5 0.1 0.072 12.3 0.1 1.5 1 0 0 1 1 1 0 Noc2p family Cnd1 PF12717.7 EGG22616.1 - 0.12 12.4 11.6 0.071 13.2 0.4 5.1 5 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 PhyH PF05721.13 EGG22618.1 - 1.1e-24 87.9 0.1 1.3e-24 87.6 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Syntaxin-6_N PF09177.11 EGG22619.1 - 2.4e-19 69.7 3.0 2.4e-19 69.7 3.0 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF16 PF01519.16 EGG22619.1 - 0.035 14.6 0.3 0.035 14.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Sec5 PF15469.6 EGG22619.1 - 0.11 12.3 4.7 0.052 13.3 2.0 1.7 1 1 0 2 2 2 0 Exocyst complex component Sec5 TMF_DNA_bd PF12329.8 EGG22619.1 - 8.2 6.5 9.6 2.2 8.4 2.7 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CCDC53 PF10152.9 EGG22620.1 - 0.00043 20.7 0.7 0.00051 20.5 0.7 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Allexi_40kDa PF05549.11 EGG22620.1 - 0.0024 17.4 0.4 0.0026 17.3 0.4 1.0 1 0 0 1 1 1 1 Allexivirus 40kDa protein LXG PF04740.12 EGG22620.1 - 0.0049 16.6 0.6 0.0054 16.5 0.6 1.1 1 0 0 1 1 1 1 LXG domain of WXG superfamily Sec6 PF06046.13 EGG22620.1 - 0.018 13.5 0.5 0.017 13.5 0.5 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec6 NPV_P10 PF05531.12 EGG22620.1 - 0.059 13.8 0.8 0.21 12.1 0.1 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein OST3_OST6 PF04756.13 EGG22621.1 - 1.2e-05 24.8 4.0 1.5e-05 24.5 4.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Vps39_2 PF10367.9 EGG22622.1 - 4.4e-27 94.7 0.0 1.4e-26 93.0 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 EGG22622.1 - 2.5e-24 86.4 0.2 5.1e-24 85.3 0.2 1.5 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 EGG22622.1 - 1.1e-18 67.5 5.6 3.9e-18 65.7 2.2 3.6 4 1 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 EGG22622.1 - 1.5e-16 60.6 4.7 1.7e-09 37.7 0.2 3.7 4 1 0 4 4 4 2 Region in Clathrin and VPS DUF2175 PF09943.9 EGG22622.1 - 0.0043 17.3 0.5 0.023 14.9 0.1 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) DUF928 PF06051.12 EGG22622.1 - 0.079 12.8 0.1 0.29 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) TPR_1 PF00515.28 EGG22622.1 - 0.14 12.0 0.9 3.8 7.5 0.9 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat zinc_ribbon_9 PF14369.6 EGG22622.1 - 0.16 12.3 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 zinc-ribbon Profilin PF00235.19 EGG22626.1 - 0.0092 16.3 0.0 0.01 16.1 0.0 1.4 1 1 0 1 1 1 1 Profilin Swi5 PF07061.11 EGG22627.1 - 0.0001 22.3 5.0 0.0001 22.3 5.0 1.7 2 0 0 2 2 2 1 Swi5 AcylCoA_dehyd_C PF12186.8 EGG22627.1 - 0.031 14.4 2.1 0.043 13.9 2.1 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal LytR_cpsA_psr PF03816.14 EGG22627.1 - 0.058 13.6 2.5 0.28 11.3 2.5 1.9 1 1 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain S-AdoMet_synt_C PF02773.16 EGG22628.1 - 5.1e-66 220.9 0.1 1.6e-65 219.3 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EGG22628.1 - 1.9e-46 157.2 0.0 4.1e-46 156.1 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EGG22628.1 - 1.3e-44 150.9 0.5 1.3e-44 150.9 0.5 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Amidinotransf PF02274.17 EGG22628.1 - 0.096 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Amidinotransferase RBFA PF02033.18 EGG22629.1 - 1.6e-09 38.1 1.3 0.00012 22.5 0.1 2.9 2 0 0 2 2 2 2 Ribosome-binding factor A NPR3 PF03666.13 EGG22631.1 - 3.3e-56 191.0 34.7 6.6e-32 110.9 23.9 3.2 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 EGG22631.1 - 0.00053 18.9 4.4 0.0015 17.4 0.0 3.0 2 1 1 3 3 3 1 Nitrogen permease regulator 2 YL1 PF05764.13 EGG22631.1 - 0.0073 16.5 8.9 0.011 15.8 8.9 1.2 1 0 0 1 1 1 1 YL1 nuclear protein LAP1C PF05609.12 EGG22631.1 - 0.16 11.1 17.2 0.26 10.4 17.2 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 EGG22631.1 - 1.1 7.8 32.1 0.021 13.4 24.0 1.9 2 0 0 2 2 2 0 Macoilin family CobT PF06213.12 EGG22632.1 - 4 6.7 7.8 5.9 6.2 7.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4175 PF13779.6 EGG22632.1 - 5.4 4.8 10.8 6.7 4.5 10.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ras PF00071.22 EGG22633.1 - 4.2e-50 169.5 0.6 6.8e-50 168.8 0.1 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGG22633.1 - 6e-32 110.4 0.2 4.1e-31 107.7 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG22633.1 - 1.5e-15 57.1 0.2 8e-15 54.7 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG22633.1 - 1.7e-07 30.8 0.0 3.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GSH-S_ATP PF02955.16 EGG22633.1 - 8.3e-06 25.3 0.0 1.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GTP_EFTU PF00009.27 EGG22633.1 - 7.2e-05 22.4 0.1 0.0011 18.5 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG22633.1 - 0.0014 18.6 0.0 0.0036 17.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGG22633.1 - 0.0029 17.1 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGG22633.1 - 0.11 12.2 0.2 13 5.6 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ald_deCOase PF11266.8 EGG22633.1 - 0.12 12.1 0.2 11 5.6 0.1 2.4 2 0 0 2 2 2 0 Long-chain fatty aldehyde decarbonylase Pkinase PF00069.25 EGG22634.1 - 6.1e-73 245.4 0.0 6.1e-73 245.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG22634.1 - 1.8e-46 158.5 0.3 3.4e-46 157.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG22634.1 - 7.7e-10 38.6 1.0 4.5e-09 36.0 1.0 2.0 1 1 0 1 1 1 1 Kinase-like TFIIA PF03153.13 EGG22634.1 - 0.028 14.4 24.7 0.039 14.0 24.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Seadorna_VP7 PF07387.11 EGG22634.1 - 0.18 10.9 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 EGG22634.1 - 1.7 8.1 5.3 0.29 10.6 0.1 2.1 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL zf-RING_2 PF13639.6 EGG22635.1 - 3.2e-12 46.6 8.3 6e-12 45.7 8.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG22635.1 - 1.9e-09 37.2 8.2 3.5e-09 36.4 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG22635.1 - 1e-08 35.0 4.4 2.4e-08 33.9 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG22635.1 - 1.6e-08 34.2 7.4 4.1e-08 32.9 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG22635.1 - 3.6e-08 33.1 4.5 5.8e-08 32.5 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGG22635.1 - 4.5e-08 33.3 12.2 1.7e-06 28.2 12.2 2.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain CUE PF02845.16 EGG22635.1 - 3e-07 30.0 0.2 6e-07 29.0 0.2 1.6 1 0 0 1 1 1 1 CUE domain Prok-RING_4 PF14447.6 EGG22635.1 - 2.6e-06 27.2 6.0 6.1e-06 26.0 6.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGG22635.1 - 1.1e-05 25.3 6.4 1.1e-05 25.3 6.4 1.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGG22635.1 - 1.2e-05 24.9 3.8 2.4e-05 24.0 3.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGG22635.1 - 0.00014 21.4 5.2 0.00028 20.4 5.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EGG22635.1 - 0.00046 20.2 6.3 0.0024 17.9 6.3 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGG22635.1 - 0.00077 19.6 4.5 0.0015 18.6 4.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING RINGv PF12906.7 EGG22635.1 - 0.062 13.4 7.9 0.16 12.1 7.9 1.8 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EGG22635.1 - 0.1 12.4 3.4 0.26 11.1 3.4 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EGG22635.1 - 0.15 12.3 6.0 0.54 10.5 6.0 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 EGG22635.1 - 1.5 9.0 5.3 3.2 7.9 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 EGG22635.1 - 1.6 9.1 7.4 4 7.8 7.4 1.7 1 0 0 1 1 1 0 RING-like domain DUF2981 PF11200.8 EGG22635.1 - 3.8 7.2 12.8 5.8 6.6 12.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) ACOX PF01756.19 EGG22636.1 - 1.1e-16 60.9 0.0 2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGG22636.1 - 3.5e-15 56.0 0.0 5.8e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGG22636.1 - 2.9e-06 27.6 0.0 9.5e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EGG22636.1 - 2.8e-05 24.7 0.1 7.5e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_N PF02771.16 EGG22636.1 - 0.0063 17.2 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cpn10 PF00166.21 EGG22637.1 - 8.8e-23 80.2 0.0 9.7e-23 80.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF2804 PF10974.8 EGG22638.1 - 1.4e-104 350.1 4.4 1.8e-104 349.8 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) Rib_5-P_isom_A PF06026.14 EGG22639.1 - 1.3e-65 220.2 0.1 1.6e-65 219.9 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 EGG22639.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain PheRS_DBD2 PF18554.1 EGG22639.1 - 0.14 12.2 0.6 0.52 10.3 0.1 2.1 2 0 0 2 2 2 0 PheRS DNA binding domain 2 Chalcone_2 PF16035.5 EGG22640.1 - 1.3e-27 96.9 0.3 1.1e-26 93.9 0.3 2.1 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EGG22640.1 - 4e-07 30.3 2.9 0.0031 17.6 0.0 2.4 2 1 1 3 3 3 2 Chalcone isomerase-like Ank_4 PF13637.6 EGG22641.1 - 0.0019 18.8 0.0 0.039 14.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22641.1 - 0.0024 18.1 0.2 0.12 12.7 0.0 3.8 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG22641.1 - 0.0061 17.1 1.1 0.2 12.3 0.1 4.2 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG22641.1 - 0.022 15.3 0.1 2.9 8.8 0.0 4.6 5 0 0 5 5 5 0 Ankyrin repeat DUF4460 PF14687.6 EGG22642.1 - 3.8e-27 94.5 0.7 1.4e-26 92.7 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 EGG22642.1 - 1.9e-05 24.6 4.0 6e-05 23.0 1.6 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4461) Fib_alpha PF08702.10 EGG22643.1 - 3.4 7.8 42.3 2.7 8.2 12.5 3.6 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 EGG22643.1 - 5.4 7.1 45.5 0.049 13.7 6.0 3.7 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein GCV_H PF01597.19 EGG22644.1 - 1e-38 132.0 0.8 1.2e-38 131.7 0.8 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EGG22644.1 - 0.0002 21.1 0.2 0.00034 20.4 0.2 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 EGG22644.1 - 0.011 15.5 0.2 0.036 13.8 0.2 1.9 1 1 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 EGG22644.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PPR_2 PF13041.6 EGG22645.1 - 7e-42 141.4 17.4 1.2e-12 47.8 0.1 9.9 4 3 7 11 11 11 9 PPR repeat family PPR PF01535.20 EGG22645.1 - 1.4e-31 106.5 24.9 4.2e-05 23.5 0.1 11.2 11 1 0 11 11 11 7 PPR repeat PPR_3 PF13812.6 EGG22645.1 - 1.4e-28 98.8 14.8 1.4e-05 25.1 0.1 7.2 3 2 1 6 6 6 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGG22645.1 - 1.5e-28 98.2 23.8 2.3e-05 24.0 0.0 10.2 11 1 0 11 11 11 6 PPR repeat PPR_long PF17177.4 EGG22645.1 - 2e-23 82.9 1.8 3e-08 33.3 0.2 3.4 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 EGG22645.1 - 6.5e-06 26.0 1.1 2.5 8.0 0.0 5.5 3 1 3 6 6 6 1 Mitochondrial ATPase expression TPR_19 PF14559.6 EGG22645.1 - 0.018 15.6 0.0 20 5.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat LINES_C PF14695.6 EGG22645.1 - 0.04 13.3 0.1 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 Lines C-terminus TPR_14 PF13428.6 EGG22645.1 - 0.23 12.4 0.0 82 4.4 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG22645.1 - 1.2 9.4 3.8 18 5.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Guanylate_cyc PF00211.20 EGG22646.1 - 0.043 13.4 0.1 0.083 12.5 0.1 1.5 1 1 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Ssl1 PF04056.14 EGG22647.1 - 3.8e-67 225.8 0.6 5.1e-67 225.4 0.6 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EGG22647.1 - 4.4e-11 42.9 28.7 1.1e-10 41.6 13.5 3.3 3 1 0 3 3 3 2 TFIIH C1-like domain VWA_2 PF13519.6 EGG22647.1 - 2.5e-09 37.7 0.0 5.6e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 EGG22647.1 - 0.0029 17.2 2.6 0.0029 17.2 2.6 1.8 2 0 0 2 2 2 1 Transcription factor Tfb4 IBR PF01485.21 EGG22647.1 - 0.015 15.5 7.9 0.015 15.5 7.9 3.1 2 2 1 3 3 3 0 IBR domain, a half RING-finger domain DZR PF12773.7 EGG22647.1 - 1.6 8.8 17.5 2.2e+02 2.0 17.7 3.0 1 1 0 1 1 1 0 Double zinc ribbon fn3 PF00041.21 EGG22648.1 - 7e-06 26.3 0.6 0.12 12.7 0.0 4.6 4 0 0 4 4 4 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 EGG22648.1 - 0.00048 20.6 8.7 0.0087 16.6 0.1 3.6 3 2 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Lys PF00062.20 EGG22648.1 - 0.02 15.1 2.8 0.35 11.1 0.1 2.4 2 0 0 2 2 2 0 C-type lysozyme/alpha-lactalbumin family TPR_2 PF07719.17 EGG22649.1 - 6.4e-13 47.7 15.4 0.015 15.4 0.1 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGG22649.1 - 1.3e-12 46.9 16.6 0.0012 18.6 3.9 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGG22649.1 - 7.5e-09 35.8 1.0 0.033 14.5 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat SET PF00856.28 EGG22649.1 - 1.5e-07 32.0 14.0 1.5e-07 32.0 14.0 4.2 3 1 0 3 3 3 1 SET domain zf-MYND PF01753.18 EGG22649.1 - 2.9e-06 27.3 12.5 2.9e-06 27.3 12.5 2.2 2 0 0 2 2 1 1 MYND finger TPR_14 PF13428.6 EGG22649.1 - 0.00021 21.8 2.0 0.16 12.9 0.0 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG22649.1 - 0.00055 19.9 16.3 0.32 11.3 0.7 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF5113 PF17140.4 EGG22649.1 - 0.34 10.7 3.0 7.2 6.4 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5113) TPR_7 PF13176.6 EGG22649.1 - 0.52 10.5 2.3 22 5.4 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGG22649.1 - 3.2 7.7 10.8 1.6 8.7 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG22649.1 - 6.8 7.6 7.5 1.4e+02 3.4 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SdiA-regulated PF06977.11 EGG22650.1 - 0.02 14.2 0.0 0.68 9.1 0.0 2.8 3 0 0 3 3 3 0 SdiA-regulated NHL PF01436.21 EGG22650.1 - 0.12 12.5 1.9 18 5.6 0.1 3.7 4 0 0 4 4 4 0 NHL repeat Exonuc_VII_L PF02601.15 EGG22652.1 - 0.037 13.6 0.3 0.057 13.0 0.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlaC_arch PF05377.11 EGG22652.1 - 0.72 10.3 0.1 0.72 10.3 0.1 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Erp_C PF06780.11 EGG22652.1 - 0.72 9.9 8.8 0.82 9.7 0.2 2.9 1 1 2 3 3 3 0 Erp protein C-terminus RecG_N PF17190.4 EGG22652.1 - 1 10.2 7.4 14 6.5 0.1 3.2 2 1 0 3 3 3 0 RecG N-terminal helical domain OmpH PF03938.14 EGG22652.1 - 1.8 8.9 9.2 0.18 12.1 4.1 1.9 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Taxilin PF09728.9 EGG22652.1 - 3.4 6.7 14.1 0.19 10.9 7.7 2.0 2 1 0 2 2 2 0 Myosin-like coiled-coil protein PspB PF06667.12 EGG22652.1 - 5.1 7.2 5.5 1.3 9.1 1.2 2.2 2 0 0 2 2 2 0 Phage shock protein B Pox_Ag35 PF03286.14 EGG22653.1 - 0.021 14.6 2.6 0.053 13.3 2.6 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4611 PF15387.6 EGG22653.1 - 1.8 8.8 11.8 12 6.2 7.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 EGG22653.1 - 3.3 5.9 8.0 5.4 5.2 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Alpha_kinase PF02816.18 EGG22654.1 - 2.4e-52 177.7 0.1 4.4e-52 176.9 0.1 1.5 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.32 EGG22654.1 - 1e-33 114.8 27.5 2.7e-07 31.1 1.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 EGG22654.1 - 4e-12 45.6 1.7 0.011 14.4 0.0 5.7 1 1 5 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGG22654.1 - 1.4e-05 24.1 2.5 0.078 11.7 0.5 4.5 2 2 2 4 4 4 2 Nup133 N terminal like WD40_like PF17005.5 EGG22654.1 - 0.0075 15.6 2.0 0.56 9.5 0.2 2.3 2 0 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 EGG22654.1 - 0.02 15.2 0.5 5.7 7.3 0.0 3.5 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Cellulase PF00150.18 EGG22655.1 - 6.6e-37 127.5 2.3 6.6e-37 127.5 2.3 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM49 PF09478.10 EGG22655.1 - 2.5e-09 37.3 1.7 2.5e-09 37.3 1.7 2.3 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 SOG2 PF10428.9 EGG22655.1 - 1.4 8.0 36.4 2.1 7.5 36.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein AAA_16 PF13191.6 EGG22656.1 - 0.0054 17.1 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG22656.1 - 0.03 14.6 0.0 0.099 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGG22656.1 - 0.17 12.2 0.0 0.39 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 EGG22656.1 - 0.2 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 LRR_6 PF13516.6 EGG22658.1 - 0.00017 21.4 1.3 0.00052 19.9 0.1 2.6 2 0 0 2 2 2 1 Leucine Rich repeat DUF3420 PF11900.8 EGG22658.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) TPR_12 PF13424.6 EGG22660.1 - 1.1e-06 28.8 0.2 0.05 13.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG22660.1 - 7.7e-06 25.6 0.6 0.23 11.6 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG22660.1 - 0.003 17.6 0.1 0.56 10.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG22660.1 - 0.017 14.9 0.0 6.3 6.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGG22660.1 - 0.052 13.4 0.2 0.76 9.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L25p PF01386.19 EGG22661.1 - 3.2e-09 37.2 0.0 6.6e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal L25p family JUPITER PF17054.5 EGG22661.1 - 0.067 12.7 4.7 0.067 12.7 3.1 1.7 1 1 1 2 2 2 0 Microtubule-Associated protein Jupiter Exo_endo_phos PF03372.23 EGG22662.1 - 3.6e-13 49.6 0.0 8.4e-12 45.1 0.0 2.6 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family BUD22 PF09073.10 EGG22664.1 - 0.22 10.9 35.5 0.26 10.6 35.5 1.1 1 0 0 1 1 1 0 BUD22 Raftlin PF15250.6 EGG22664.1 - 1 8.0 13.8 1.2 7.8 13.8 1.1 1 0 0 1 1 1 0 Raftlin DUF908 PF06012.12 EGG22664.1 - 1.2 8.4 7.4 1.8 7.9 7.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SDA1 PF05285.12 EGG22664.1 - 2.4 7.5 40.5 3.2 7.1 40.5 1.2 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.10 EGG22664.1 - 6 6.1 32.4 8.3 5.7 32.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hamartin PF04388.12 EGG22664.1 - 8.3 4.9 11.4 8.8 4.8 11.4 1.1 1 0 0 1 1 1 0 Hamartin protein CNDH2_C PF16858.5 EGG22664.1 - 9.3 6.0 23.9 13 5.6 23.9 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Pkinase PF00069.25 EGG22665.1 - 8.7e-64 215.4 0.1 1.4e-63 214.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG22665.1 - 2e-48 165.0 0.1 3e-48 164.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG22665.1 - 3.5e-05 23.3 0.0 0.00034 20.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGG22665.1 - 0.0008 18.3 10.4 0.013 14.3 10.4 2.7 1 1 0 1 1 1 1 Fungal protein kinase SH3_1 PF00018.28 EGG22665.1 - 0.0027 17.3 0.0 0.0052 16.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG22665.1 - 0.0032 17.1 0.0 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Haspin_kinase PF12330.8 EGG22665.1 - 0.014 14.4 1.2 0.088 11.7 1.1 2.2 1 1 0 1 1 1 0 Haspin like kinase domain SH3_9 PF14604.6 EGG22665.1 - 0.014 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain FTA2 PF13095.6 EGG22665.1 - 0.033 13.8 0.4 1.9 8.0 0.1 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 SPECT1 PF18680.1 EGG22665.1 - 0.036 13.7 2.1 0.073 12.7 0.6 2.2 3 0 0 3 3 3 0 Plasmodium host cell traversal SPECT1 APH PF01636.23 EGG22665.1 - 0.061 13.2 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ca_hom_mod PF14798.6 EGG22666.1 - 0.046 12.8 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator Nop14 PF04147.12 EGG22667.1 - 8.8e-210 699.2 61.5 1.1e-209 698.9 61.5 1.0 1 0 0 1 1 1 1 Nop14-like family Jak1_Phl PF17887.1 EGG22667.1 - 0.052 13.5 0.3 0.052 13.5 0.3 4.5 5 1 0 5 5 5 0 Jak1 pleckstrin homology-like domain Lactate_perm PF02652.14 EGG22667.1 - 0.12 11.0 0.2 0.22 10.2 0.2 1.3 1 0 0 1 1 1 0 L-lactate permease TK PF00265.18 EGG22668.1 - 4e-65 219.0 0.0 5.1e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Thymidine kinase ATPase_2 PF01637.18 EGG22668.1 - 0.00062 19.7 0.1 0.00087 19.3 0.1 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EGG22668.1 - 0.0024 17.9 0.1 0.0049 16.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain LRR_6 PF13516.6 EGG22669.1 - 2.3e-11 42.8 20.2 0.0096 15.9 0.3 7.4 7 0 0 7 7 7 4 Leucine Rich repeat F-box-like PF12937.7 EGG22669.1 - 0.00023 21.0 0.0 0.00046 20.0 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG22669.1 - 0.0046 16.8 0.2 0.027 14.4 0.2 2.2 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EGG22669.1 - 0.009 16.4 15.6 0.016 15.6 6.5 6.7 6 2 1 7 7 7 2 Leucine Rich repeats (2 copies) A_deaminase PF00962.22 EGG22670.1 - 8.2e-27 94.4 0.0 1.2e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 EGG22670.1 - 5.1e-15 55.5 0.5 1.1e-14 54.5 0.1 1.9 2 0 0 2 2 2 1 Adenosine/AMP deaminase N-terminal SR-25 PF10500.9 EGG22670.1 - 0.21 11.2 7.0 0.3 10.6 7.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase_Tyr PF07714.17 EGG22671.1 - 7.6e-61 205.6 0.0 1e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG22671.1 - 9.3e-49 166.1 0.0 1.4e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.22 EGG22671.1 - 6.1e-18 64.8 22.4 5.9e-11 42.4 4.9 2.7 3 0 0 3 3 3 2 LIM domain APH PF01636.23 EGG22671.1 - 4.9e-05 23.4 0.0 7.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGG22671.1 - 0.00015 20.7 0.0 0.0003 19.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGG22671.1 - 0.00036 19.9 0.0 0.00036 19.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGG22671.1 - 0.00049 19.8 0.4 0.022 14.3 0.0 2.2 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 EGG22671.1 - 0.00079 19.1 0.2 0.56 9.8 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGG22671.1 - 0.0063 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGG22671.1 - 0.42 9.5 7.0 0.05 12.5 0.2 2.4 2 1 0 2 2 2 0 Haspin like kinase domain WD40 PF00400.32 EGG22672.1 - 1.4e-28 98.6 17.4 7.3e-09 36.1 0.2 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG22672.1 - 1.1e-07 32.0 0.0 3.1 8.2 0.0 5.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG22672.1 - 3.2e-05 23.9 0.1 0.013 15.4 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGG22672.1 - 0.0025 17.2 0.0 0.55 9.5 0.0 2.7 2 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 EGG22672.1 - 0.075 12.0 0.0 1.1 8.2 0.0 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGG22672.1 - 0.086 11.5 0.7 1.7 7.2 0.1 2.7 2 1 0 3 3 3 0 Nucleoporin Nup120/160 LPMO_10 PF03067.15 EGG22673.1 - 1.7e-35 123.4 1.0 2e-35 123.2 1.0 1.0 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading FrpC PF06901.12 EGG22673.1 - 0.036 13.7 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 RTX iron-regulated protein FrpC Mucin PF01456.17 EGG22674.1 - 0.00095 19.2 8.1 0.00095 19.2 8.1 3.0 2 1 0 2 2 2 1 Mucin-like glycoprotein Spore_YhcN_YlaJ PF09580.10 EGG22674.1 - 0.89 9.6 15.3 0.72 9.9 4.8 3.2 2 1 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Oxidored_FMN PF00724.20 EGG22675.1 - 3.2e-72 243.6 0.0 5e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Isochorismatase PF00857.20 EGG22675.1 - 1.3e-24 87.4 0.0 3.5e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 Isochorismatase family Dus PF01207.17 EGG22675.1 - 0.00015 21.0 0.0 0.033 13.3 0.0 2.4 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) Pmp3 PF01679.17 EGG22676.1 - 0.0023 18.1 2.7 0.008 16.4 0.1 3.0 2 0 0 2 2 2 1 Proteolipid membrane potential modulator AICARFT_IMPCHas PF01808.18 EGG22676.1 - 0.055 12.9 0.1 0.087 12.3 0.1 1.2 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme DUF4412 PF14371.6 EGG22676.1 - 0.084 12.7 0.3 3.8 7.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4412) NPR3 PF03666.13 EGG22676.1 - 0.87 8.3 4.2 1.3 7.8 4.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pmp3 PF01679.17 EGG22677.1 - 1.6e-09 37.8 0.8 3.4e-09 36.8 0.8 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1056 PF06341.11 EGG22677.1 - 0.073 13.4 2.2 0.12 12.8 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1056) FG-GAP PF01839.23 EGG22678.1 - 7.4e-28 96.3 10.8 1.7e-09 37.6 1.6 5.2 5 0 0 5 5 5 4 FG-GAP repeat Zn_dep_PLPC PF00882.18 EGG22678.1 - 2.5e-21 76.5 0.3 6.2e-21 75.2 0.3 1.7 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.6 EGG22678.1 - 3.3e-14 53.2 8.8 0.013 16.1 0.3 5.1 4 0 0 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 EGG22678.1 - 0.084 12.2 0.5 6 6.2 0.0 3.2 4 0 0 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region PliI PF16743.5 EGG22678.1 - 0.13 12.1 0.1 5 6.9 0.1 2.9 3 0 0 3 3 3 0 Periplasmic lysozyme inhibitor of I-type lysozyme EF-hand_5 PF13202.6 EGG22678.1 - 0.22 11.1 0.6 5.1 6.8 0.0 2.7 2 0 0 2 2 2 0 EF hand ATP-sulfurylase PF01747.17 EGG22680.1 - 0.003 17.0 0.1 0.0051 16.3 0.1 1.3 1 0 0 1 1 1 1 ATP-sulfurylase Pox_Ag35 PF03286.14 EGG22680.1 - 0.15 11.8 2.7 0.27 11.0 2.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Fer2_3 PF13085.6 EGG22681.1 - 6.1e-32 109.9 0.0 9.8e-32 109.2 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EGG22681.1 - 1.5e-08 35.0 2.2 1.5e-08 35.0 2.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGG22681.1 - 3.6e-08 33.7 7.1 4.9e-08 33.3 4.1 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGG22681.1 - 6.7e-08 32.5 1.6 6.7e-08 32.5 1.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EGG22681.1 - 0.017 15.1 0.2 0.017 15.1 0.2 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 EGG22681.1 - 0.021 15.0 0.6 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGG22681.1 - 2.2 8.5 13.8 4.9 7.4 9.0 3.1 2 1 1 3 3 3 0 4Fe-4S dicluster domain SRF-TF PF00319.18 EGG22682.1 - 1.1e-22 79.2 0.5 2.2e-22 78.2 0.5 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Dict-STAT-coil PF09267.10 EGG22683.1 - 4e-45 152.9 12.3 4e-45 152.9 12.3 4.8 4 0 0 4 4 4 1 Dictyostelium STAT, coiled coil EF-hand_12 PF17901.1 EGG22683.1 - 1.4e-40 137.6 2.0 1.4e-40 137.6 2.0 3.2 3 0 0 3 3 3 1 EF-hand fold domain STATa_Ig PF18214.1 EGG22683.1 - 4.6e-39 133.2 7.2 9.7e-20 70.8 0.1 4.0 3 0 0 3 3 3 2 STATa Immunoglobulin-like domain SH2 PF00017.24 EGG22683.1 - 0.0092 16.1 0.0 0.064 13.4 0.0 2.5 2 0 0 2 2 2 1 SH2 domain CPP1-like PF11833.8 EGG22683.1 - 0.16 11.6 0.7 0.43 10.2 0.7 1.7 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SSP160 PF06933.11 EGG22684.1 - 0.01 14.1 15.1 0.023 13.0 15.1 1.7 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-CCCH PF00642.24 EGG22684.1 - 0.054 13.4 2.8 0.098 12.6 2.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Selenoprotein_S PF06936.11 EGG22684.1 - 0.37 10.6 7.6 1.1 9.0 7.6 1.8 1 0 0 1 1 1 0 Selenoprotein S (SelS) Integrase_H2C2 PF17921.1 EGG22685.1 - 4.3e-16 58.8 0.3 4.3e-16 58.8 0.3 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 EGG22685.1 - 4.7e-15 55.8 1.7 6.8e-15 55.2 0.5 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 EGG22685.1 - 4.3e-14 52.7 0.0 1.2e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 EGG22685.1 - 4.2e-08 33.2 0.2 1.8e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 EGG22685.1 - 0.00051 20.2 0.0 0.0021 18.2 0.0 2.1 1 0 0 1 1 1 1 H2C2 zinc finger DUF3437 PF11919.8 EGG22685.1 - 0.0067 16.3 0.2 0.027 14.4 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) RNase_H PF00075.24 EGG22685.1 - 0.067 13.4 0.3 0.31 11.2 0.0 2.3 2 1 0 2 2 2 0 RNase H RVT_3 PF13456.6 EGG22685.1 - 0.095 12.5 0.2 0.92 9.3 0.0 2.6 2 0 0 2 2 2 0 Reverse transcriptase-like Glyco_transf_10 PF00852.19 EGG22686.1 - 8.2e-34 116.8 2.1 1.9e-33 115.7 2.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Laminin_G_3 PF13385.6 EGG22686.1 - 1.3e-22 80.6 0.3 2.8e-22 79.5 0.3 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sialidase PF02973.16 EGG22686.1 - 0.00032 20.3 0.6 0.00087 18.8 0.6 1.7 1 0 0 1 1 1 1 Sialidase, N-terminal domain NADH-u_ox-rdase PF10785.9 EGG22686.1 - 0.85 10.4 3.5 1.6 9.5 1.6 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit PBP1_TM PF14812.6 EGG22686.1 - 2.4 8.6 7.4 60 4.1 5.5 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Metallophos_2 PF12850.7 EGG22687.1 - 1.3e-21 77.5 0.2 1.8e-21 77.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGG22687.1 - 0.00045 20.8 0.7 0.3 11.6 0.7 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NDUF_C2 PF06374.11 EGG22687.1 - 0.0067 16.5 0.1 0.013 15.7 0.1 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) SPX PF03105.19 EGG22688.1 - 0.015 15.2 17.2 19 5.0 0.0 3.5 3 1 0 3 3 3 0 SPX domain Cpn60_TCP1 PF00118.24 EGG22689.1 - 2.7e-48 164.8 0.1 1.4e-22 80.0 0.0 3.9 3 1 1 4 4 4 3 TCP-1/cpn60 chaperonin family EPL1 PF10513.9 EGG22689.1 - 0.0017 18.8 17.9 0.1 12.9 0.7 2.6 2 0 0 2 2 2 2 Enhancer of polycomb-like PIP5K PF01504.18 EGG22689.1 - 0.0059 15.9 10.0 0.048 12.9 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase CPSF100_C PF13299.6 EGG22689.1 - 0.0079 16.4 5.7 1.2 9.3 0.0 2.3 2 0 0 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal Ctr PF04145.15 EGG22689.1 - 0.099 13.3 3.9 8.7 6.9 1.5 2.6 3 0 0 3 3 2 0 Ctr copper transporter family MID_MedPIWI PF18296.1 EGG22689.1 - 0.29 10.9 17.4 0.49 10.1 4.7 2.4 2 0 0 2 2 2 0 MID domain of medPIWI Connexin PF00029.19 EGG22689.1 - 0.43 10.3 4.0 6.2 6.5 1.8 2.4 2 0 0 2 2 2 0 Connexin ALMT PF11744.8 EGG22689.1 - 0.57 9.0 14.8 0.9 8.3 0.8 2.3 2 0 0 2 2 2 0 Aluminium activated malate transporter POX PF07526.11 EGG22689.1 - 1.8 9.1 12.4 5.5 7.6 0.7 2.7 2 0 0 2 2 2 0 Associated with HOX CSG2 PF16965.5 EGG22689.1 - 3.9 6.3 12.7 5.8 5.8 0.8 2.3 2 0 0 2 2 2 0 Ceramide synthase regulator DUF2448 PF10476.9 EGG22689.1 - 4.1 7.2 7.2 2.5 7.9 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) GNAT_acetyltr_2 PF13718.6 EGG22689.1 - 5.1 6.4 11.5 13 5.1 0.6 2.5 2 0 0 2 2 2 0 GNAT acetyltransferase 2 AAR2 PF05282.11 EGG22689.1 - 5.1 6.4 15.2 15 4.8 0.8 3.1 3 0 0 3 3 3 0 AAR2 protein DUF2407_C PF13373.6 EGG22689.1 - 5.8 7.1 15.9 5.9 7.1 1.7 2.6 2 0 0 2 2 2 0 DUF2407 C-terminal domain Apc15p PF05841.11 EGG22689.1 - 9.8 7.0 40.4 9.9 7.0 11.8 2.7 2 0 0 2 2 2 0 Apc15p protein HTH_36 PF13730.6 EGG22690.1 - 0.04 13.9 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain EOS1 PF12326.8 EGG22690.1 - 0.056 13.4 4.4 0.086 12.8 4.4 1.3 1 0 0 1 1 1 0 N-glycosylation protein SapB_1 PF05184.15 EGG22690.1 - 0.16 12.0 1.7 0.32 11.1 0.5 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 DUF4407 PF14362.6 EGG22690.1 - 0.24 10.7 15.2 0.43 9.9 15.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EGG22690.1 - 0.28 11.2 0.1 0.28 11.2 0.1 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 EGG22690.1 - 0.61 7.9 15.3 0.76 7.6 15.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prominin PF05478.11 EGG22690.1 - 0.67 7.8 20.3 0.17 9.8 14.8 1.9 1 1 0 2 2 2 0 Prominin TFIIA PF03153.13 EGG22690.1 - 1.2 9.1 24.2 1.6 8.6 24.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.6 EGG22690.1 - 1.6 6.6 17.4 1.8 6.4 17.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Presenilin PF01080.17 EGG22690.1 - 3.8 6.2 8.8 5 5.8 8.8 1.3 1 0 0 1 1 1 0 Presenilin DUF1075 PF06388.11 EGG22690.1 - 4.1 7.5 7.1 5.8 7.0 6.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1075) RP-C_C PF11800.8 EGG22690.1 - 6 6.9 19.3 6.1 6.9 18.0 1.7 1 1 0 1 1 1 0 Replication protein C C-terminal region DEAD PF00270.29 EGG22691.1 - 3.2e-39 134.5 1.0 6.2e-39 133.6 1.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG22691.1 - 3.3e-29 101.5 0.0 2.1e-27 95.7 0.0 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG22691.1 - 4.5e-07 30.0 0.1 4.5e-07 30.0 0.1 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit TFIIA PF03153.13 EGG22692.1 - 0.24 11.3 38.9 0.39 10.7 38.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Img2 PF05046.14 EGG22693.1 - 4.4e-16 58.9 0.0 8.1e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) DUF961 PF06125.11 EGG22693.1 - 0.036 14.4 0.1 0.068 13.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) ABC_membrane PF00664.23 EGG22693.1 - 0.058 13.0 1.5 2.4 7.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter transmembrane region PH PF00169.29 EGG22694.1 - 2.8e-09 37.4 0.9 2.8e-09 37.4 0.9 3.1 4 0 0 4 4 4 1 PH domain PH_11 PF15413.6 EGG22694.1 - 0.051 14.0 0.7 0.051 14.0 0.7 3.4 3 0 0 3 3 3 0 Pleckstrin homology domain DUF573 PF04504.14 EGG22694.1 - 0.46 11.2 14.3 1.3 9.8 1.1 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF573 PH_9 PF15410.6 EGG22694.1 - 4.4 7.7 10.9 4.6 7.6 0.3 3.9 3 1 0 3 3 3 0 Pleckstrin homology domain DUF900 PF05990.12 EGG22695.1 - 7.8e-23 81.2 0.1 1.3e-22 80.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 EGG22695.1 - 0.004 17.8 0.0 0.0063 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF599 PF04654.12 EGG22696.1 - 2.1e-51 174.3 3.2 2.1e-51 174.3 3.2 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF599 SPX PF03105.19 EGG22696.1 - 0.0048 16.9 8.1 0.0064 16.5 8.1 1.1 1 0 0 1 1 1 1 SPX domain Macoilin PF09726.9 EGG22696.1 - 0.23 10.0 7.2 0.29 9.6 7.2 1.2 1 0 0 1 1 1 0 Macoilin family FAM199X PF15814.5 EGG22696.1 - 0.24 10.4 10.7 0.42 9.6 10.7 1.4 1 0 0 1 1 1 0 Protein family FAM199X CEL_III_C PF18054.1 EGG22696.1 - 4.3 7.4 10.6 3.2 7.8 5.4 2.3 2 0 0 2 2 2 0 CEL-III C-terminal ArfGap PF01412.18 EGG22697.1 - 2.2e-42 143.8 0.3 2.2e-42 143.8 0.3 2.8 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf LTV PF04180.14 EGG22698.1 - 1.1e-06 28.7 10.5 1.1e-06 28.7 10.5 4.9 1 1 2 3 3 3 1 Low temperature viability protein LMBR1 PF04791.16 EGG22698.1 - 0.48 9.3 7.4 0.69 8.7 7.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein RasGEF PF00617.19 EGG22699.1 - 6.6e-58 195.8 1.9 6.6e-58 195.8 1.9 2.5 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 EGG22699.1 - 5.2e-22 78.1 1.3 5.2e-22 78.1 1.3 4.1 4 0 0 4 4 4 1 RasGEF N-terminal motif CH PF00307.31 EGG22699.1 - 1.4e-10 41.3 1.1 4.9e-10 39.6 0.1 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain ABC1 PF03109.16 EGG22700.1 - 1.1e-24 86.9 0.2 3.4e-24 85.3 0.0 1.9 2 0 0 2 2 2 1 ABC1 family TMEM154 PF15102.6 EGG22700.1 - 0.12 12.3 2.7 0.078 12.9 0.4 1.8 1 1 1 2 2 2 0 TMEM154 protein family zf-C2H2_4 PF13894.6 EGG22701.1 - 8.5e-06 26.2 5.1 0.0025 18.5 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGG22701.1 - 1.8e-05 24.9 4.0 0.01 16.3 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 EGG22701.1 - 0.0037 17.5 1.0 0.0037 17.5 1.0 2.5 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 EGG22701.1 - 0.017 15.5 1.0 7 7.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ima1_N PF09779.9 EGG22701.1 - 0.032 15.1 0.3 0.066 14.1 0.3 1.5 1 0 0 1 1 1 0 Ima1 N-terminal domain zf-C2H2_jaz PF12171.8 EGG22701.1 - 0.055 13.8 14.4 0.08 13.3 0.6 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EGG22701.1 - 0.35 10.8 4.2 6.1 6.9 1.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 EGG22701.1 - 2.2 8.2 4.0 6.1 6.8 0.4 2.7 2 1 1 3 3 3 0 Rad50 zinc hook motif zf-H2C2_2 PF13465.6 EGG22701.1 - 5 7.7 8.0 3.6 8.2 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Radical_SAM_C PF16199.5 EGG22702.1 - 2.3e-31 107.6 0.0 4.3e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EGG22702.1 - 1.8e-20 74.0 0.0 5.4e-20 72.4 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EGG22702.1 - 1e-11 45.1 0.1 1.8e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG22702.1 - 4.1e-06 26.7 0.1 1.2e-05 25.3 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG22702.1 - 0.00054 20.3 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG22702.1 - 0.031 14.2 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF2505 PF10698.9 EGG22703.1 - 0.11 12.7 1.3 0.18 11.9 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) Band_3_cyto PF07565.13 EGG22703.1 - 1.9 8.2 11.4 0.24 11.2 6.7 1.9 1 1 1 2 2 2 0 Band 3 cytoplasmic domain Hid1 PF12722.7 EGG22703.1 - 2.1 6.4 16.5 3 5.9 16.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PI3K_1B_p101 PF10486.9 EGG22703.1 - 2.8 5.6 9.5 3.7 5.2 9.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 EGG22703.1 - 8.2 5.1 13.5 2.3 6.9 10.5 1.6 2 0 0 2 2 2 0 Presenilin Mucin PF01456.17 EGG22704.1 - 0.47 10.4 12.4 1 9.4 12.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein MCM PF00493.23 EGG22705.1 - 5.5e-71 238.2 0.2 1.2e-70 237.1 0.2 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGG22705.1 - 2.7e-20 72.5 0.1 6.1e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGG22705.1 - 2.8e-18 66.1 1.5 8.9e-18 64.5 1.5 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGG22705.1 - 7.2e-09 35.3 2.2 6.3e-06 25.7 0.0 2.8 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGG22705.1 - 7.6e-07 29.2 0.0 2.1e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGG22705.1 - 0.0012 18.6 0.3 0.0049 16.6 0.3 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 EGG22705.1 - 0.0016 18.8 0.3 0.0057 17.1 0.3 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGG22705.1 - 0.0053 16.5 1.3 0.011 15.4 1.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG22705.1 - 0.0084 16.5 0.5 0.058 13.8 0.5 2.6 1 1 0 1 1 1 1 AAA ATPase domain COPI_C PF06957.11 EGG22705.1 - 0.083 11.6 8.6 0.037 12.8 6.0 1.8 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Zn-ribbon_8 PF09723.10 EGG22705.1 - 0.087 13.0 1.6 0.28 11.3 1.6 1.9 1 0 0 1 1 1 0 Zinc ribbon domain AAA_22 PF13401.6 EGG22705.1 - 0.13 12.5 0.4 1 9.7 0.4 2.3 1 1 0 1 1 1 0 AAA domain Pes-10 PF07149.11 EGG22705.1 - 0.35 9.9 14.9 0.89 8.5 14.9 1.6 1 0 0 1 1 1 0 Pes-10 GRIN_C PF15235.6 EGG22705.1 - 2.3 8.4 9.5 0.21 11.8 4.4 1.9 2 0 0 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus TPR_1 PF00515.28 EGG22706.1 - 2e-17 62.2 7.2 0.00065 19.4 0.2 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGG22706.1 - 2.8e-15 55.1 9.4 0.00091 19.2 0.1 5.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGG22706.1 - 2.2e-13 49.6 10.0 0.0037 16.9 0.3 6.1 2 2 4 6 6 6 3 TPR repeat TPR_20 PF14561.6 EGG22706.1 - 5.4e-13 49.1 7.7 0.00024 21.3 0.7 5.5 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG22706.1 - 1.6e-12 47.8 0.3 4.1e-05 24.1 0.2 4.7 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG22706.1 - 5.7e-12 45.1 15.1 0.0002 21.5 0.3 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGG22706.1 - 1.4e-11 44.2 2.1 0.0034 18.1 0.1 5.1 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG22706.1 - 1.7e-10 40.2 2.4 0.48 10.6 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG22706.1 - 1.4e-09 38.3 5.7 0.014 15.9 0.1 4.4 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG22706.1 - 6.9e-09 35.2 6.4 0.018 15.2 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGG22706.1 - 4.2e-06 27.0 8.9 0.043 14.1 0.7 4.3 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGG22706.1 - 5.7e-06 26.4 0.2 0.0066 16.6 0.1 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG22706.1 - 0.0001 22.7 3.3 5.6 7.8 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat rRNA_proc-arch PF13234.6 EGG22706.1 - 0.00019 21.4 1.1 0.011 15.7 0.1 2.4 2 0 0 2 2 2 1 rRNA-processing arch domain BTAD PF03704.17 EGG22706.1 - 0.0031 17.9 0.9 0.26 11.7 0.2 3.0 2 1 1 3 3 3 1 Bacterial transcriptional activator domain ChAPs PF09295.10 EGG22706.1 - 0.0057 15.7 2.1 0.83 8.6 0.0 2.9 1 1 2 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 EGG22706.1 - 0.0074 16.1 10.7 3.7 7.5 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF4248 PF14053.6 EGG22706.1 - 0.01 15.9 0.5 1.2 9.2 0.0 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4248) ANAPC3 PF12895.7 EGG22706.1 - 0.011 15.9 5.4 0.96 9.7 0.2 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BRK PF07533.16 EGG22706.1 - 0.022 14.4 0.1 0.081 12.6 0.0 2.0 2 0 0 2 2 2 0 BRK domain HEAT_2 PF13646.6 EGG22706.1 - 0.16 12.4 0.1 0.97 9.9 0.0 2.2 2 1 1 3 3 3 0 HEAT repeats PPTA PF01239.22 EGG22706.1 - 0.16 11.7 1.6 1.8 8.4 0.1 2.7 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat RSS_P20 PF11757.8 EGG22706.1 - 0.28 11.7 3.0 0.23 12.0 0.4 2.2 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain B56 PF01603.20 EGG22707.1 - 3.8e-160 533.4 8.7 3.8e-160 533.4 8.7 1.8 1 1 1 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF4407 PF14362.6 EGG22707.1 - 0.35 10.2 7.2 0.51 9.6 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 EGG22707.1 - 0.74 8.5 8.2 1.4 7.6 8.2 1.6 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 EGG22707.1 - 4 7.4 16.6 0.72 9.9 11.3 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Neur_chan_memb PF02932.16 EGG22707.1 - 5 7.1 8.3 12 5.9 8.3 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 EGG22707.1 - 5.9 6.8 31.4 0.37 10.7 23.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TPR_2 PF07719.17 EGG22708.1 - 1.1e-28 97.0 38.2 0.0045 17.0 0.0 20.0 21 0 0 21 21 20 8 Tetratricopeptide repeat TPR_8 PF13181.6 EGG22708.1 - 1.5e-25 87.2 45.1 3.9e-05 23.5 0.1 19.0 19 0 0 19 19 18 6 Tetratricopeptide repeat TPR_17 PF13431.6 EGG22708.1 - 5.4e-19 67.1 47.1 0.00087 19.5 0.1 16.0 17 0 0 17 17 17 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGG22708.1 - 4.2e-18 64.5 0.0 0.37 11.8 0.0 13.6 14 3 2 16 16 13 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGG22708.1 - 2.4e-17 61.9 47.0 9.6e-05 22.0 0.1 18.3 21 0 0 21 21 20 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGG22708.1 - 1.9e-15 57.1 20.5 0.00023 21.6 0.0 12.4 11 4 4 16 16 16 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGG22708.1 - 4.4e-14 51.9 21.1 0.038 13.7 0.2 13.3 15 0 0 15 15 15 3 TPR repeat TPR_12 PF13424.6 EGG22708.1 - 1.5e-13 50.8 21.0 0.65 10.3 0.0 12.4 12 3 2 14 14 14 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG22708.1 - 4e-12 46.2 32.1 6.7e-07 29.5 1.1 8.3 9 2 1 10 10 10 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGG22708.1 - 3.1e-10 40.0 9.8 7 7.5 0.0 12.3 14 0 0 14 14 11 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG22708.1 - 9.6e-10 39.0 0.0 15 6.4 0.0 9.5 9 2 1 10 10 10 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG22708.1 - 7e-06 25.7 18.5 4.6 7.5 0.0 11.1 14 0 0 14 14 12 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGG22708.1 - 0.00022 21.0 2.1 47 4.0 0.0 7.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGG22708.1 - 0.021 15.1 12.2 0.36 11.2 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGG22708.1 - 0.041 14.0 0.0 13 6.1 0.0 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGG22708.1 - 0.19 12.2 2.1 73 3.8 0.0 4.5 5 0 0 5 5 4 0 Alkyl sulfatase dimerisation MBOAT PF03062.19 EGG22709.1 - 3.9e-27 95.5 33.5 3.9e-27 95.5 33.5 2.4 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family YajC PF02699.15 EGG22709.1 - 0.19 11.6 2.8 0.28 11.1 0.2 2.5 2 0 0 2 2 2 0 Preprotein translocase subunit DUF2516 PF10724.9 EGG22709.1 - 1.8 8.9 0.0 1.8 8.9 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2516) dUTPase PF00692.19 EGG22710.1 - 0.00079 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 dUTPase ZinT PF09223.11 EGG22710.1 - 0.15 12.0 3.3 19 5.1 0.0 3.3 2 1 1 3 3 3 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment Pkinase PF00069.25 EGG22711.1 - 1.3e-60 205.0 0.0 2.8e-60 203.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG22711.1 - 3.2e-45 154.4 0.0 5.8e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG22711.1 - 0.0058 15.5 0.0 0.0058 15.5 0.0 2.9 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 EGG22711.1 - 0.02 14.8 0.1 0.037 13.9 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ribosomal_L24 PF17136.4 EGG22711.1 - 0.81 10.1 3.0 0.48 10.9 0.4 1.9 2 0 0 2 2 2 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 DUF1771 PF08590.10 EGG22712.1 - 3.9e-20 72.0 5.9 8.5e-20 70.9 5.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EGG22712.1 - 1e-07 32.2 0.2 2.5e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Smr domain zf-CCCH_2 PF14608.6 EGG22712.1 - 6.4e-05 23.3 26.4 0.033 14.7 2.1 3.5 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EGG22712.1 - 6.7e-05 23.1 13.4 0.0055 16.9 13.5 3.2 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 EGG22712.1 - 0.00055 19.7 23.2 0.0023 17.7 1.0 3.8 4 0 0 4 4 4 3 CCCH-type zinc finger zf-CCCH PF00642.24 EGG22712.1 - 0.008 16.1 0.4 0.008 16.1 0.4 4.0 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGG22712.1 - 0.056 13.5 0.7 0.056 13.5 0.7 5.1 5 1 0 5 5 5 0 Zinc finger domain Presenilin PF01080.17 EGG22712.1 - 8.5 5.0 17.6 3.4 6.3 14.2 2.0 2 0 0 2 2 2 0 Presenilin EF-hand_1 PF00036.32 EGG22713.1 - 4.7e-20 69.6 4.5 1.2e-05 24.5 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGG22713.1 - 2.4e-18 64.4 5.2 7.4e-05 22.4 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EGG22713.1 - 4.4e-17 60.7 6.9 4e-06 26.1 0.3 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGG22713.1 - 2.4e-14 53.5 6.9 3.3e-11 43.5 0.6 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGG22713.1 - 4.4e-10 39.2 4.6 0.018 14.9 0.1 3.8 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGG22713.1 - 0.00035 20.9 1.4 3.6 7.9 0.0 3.4 2 2 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGG22713.1 - 0.00089 19.2 0.5 1.6 8.7 0.3 2.8 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EGG22713.1 - 0.0011 19.1 0.4 6 7.1 0.0 3.4 3 0 0 3 3 3 2 Dockerin type I domain TMF_TATA_bd PF12325.8 EGG22714.1 - 3.4e-28 98.2 14.6 3.4e-28 98.2 14.6 8.3 2 1 8 10 10 10 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EGG22714.1 - 8.6e-13 48.1 11.6 8.6e-13 48.1 11.6 11.4 4 3 7 11 11 11 1 TATA element modulatory factor 1 DNA binding ANAPC_CDC26 PF10471.9 EGG22714.1 - 0.0026 18.5 10.0 0.0026 18.5 10.0 8.3 5 1 1 6 6 6 1 Anaphase-promoting complex APC subunit CDC26 Yqai PF09466.10 EGG22714.1 - 0.28 11.5 2.0 0.96 9.8 2.0 1.9 1 0 0 1 1 1 0 Hypothetical protein Yqai Cystatin PF00031.21 EGG22715.1 - 3.7e-11 43.1 0.2 4.3e-11 42.9 0.2 1.1 1 0 0 1 1 1 1 Cystatin domain Cystatin PF00031.21 EGG22716.1 - 1.6e-09 37.9 0.5 1.8e-09 37.7 0.5 1.1 1 0 0 1 1 1 1 Cystatin domain SNARE_assoc PF09335.11 EGG22718.1 - 2.1e-08 34.7 2.1 1.3e-07 32.1 0.1 3.0 3 1 0 3 3 3 1 SNARE associated Golgi protein EMC3_TMCO1 PF01956.16 EGG22718.1 - 0.14 11.9 1.9 6.3 6.5 0.0 2.8 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like AKAP7_NLS PF10469.9 EGG22721.1 - 1.2e-16 61.3 0.4 1.3e-16 61.1 0.4 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 EGG22721.1 - 0.081 12.8 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Endomucin PF07010.12 EGG22722.1 - 1.1 9.2 6.5 2.1 8.2 6.5 1.4 1 0 0 1 1 1 0 Endomucin MCD PF05292.11 EGG22723.1 - 6.5e-50 170.1 3.1 4.6e-48 164.0 0.1 3.3 2 1 0 2 2 2 1 Malonyl-CoA decarboxylase C-terminal domain RhoGEF PF00621.20 EGG22723.1 - 2.2e-48 164.9 1.2 2.2e-48 164.9 1.2 3.7 3 1 0 3 3 3 1 RhoGEF domain FYVE PF01363.21 EGG22723.1 - 1.3e-16 60.5 11.8 1.3e-16 60.5 11.8 2.1 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 EGG22723.1 - 1.5e-11 44.7 0.9 1.5e-11 44.7 0.9 3.3 3 0 0 3 3 3 1 PH domain IQ_SEC7_PH PF16453.5 EGG22723.1 - 6.5e-06 26.2 0.2 2e-05 24.6 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 EGG22723.1 - 0.084 13.0 0.3 0.23 11.6 0.3 1.8 1 0 0 1 1 1 0 PH domain IBR PF01485.21 EGG22723.1 - 0.22 11.8 8.3 0.84 9.9 8.3 2.0 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Aldo_ket_red PF00248.21 EGG22724.1 - 1.1e-53 182.3 0.0 1.2e-51 175.7 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Transglut_core PF01841.19 EGG22725.1 - 4.7e-12 46.4 0.0 1.1e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Anoctamin PF04547.12 EGG22726.1 - 2.5e-93 313.4 22.4 3.4e-93 312.9 22.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel RSN1_7TM PF02714.15 EGG22726.1 - 0.0022 17.3 20.3 0.0022 17.3 20.3 3.4 2 1 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate Pox_EPC_I2-L1 PF12575.8 EGG22726.1 - 0.0073 16.5 6.0 0.1 12.9 0.3 3.6 3 0 0 3 3 3 2 Poxvirus entry protein complex L1 and I2 Gar1 PF04410.14 EGG22727.1 - 3.9e-26 91.7 0.0 5.1e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Band_7 PF01145.25 EGG22728.1 - 8.2e-25 87.8 1.3 1.3e-24 87.2 1.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 EGG22728.1 - 0.0054 16.9 0.7 0.011 15.9 0.7 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 Peptidase_S66 PF02016.15 EGG22728.1 - 0.14 12.3 0.2 0.38 10.9 0.1 1.6 1 1 0 1 1 1 0 LD-carboxypeptidase N-terminal domain TPR_2 PF07719.17 EGG22729.1 - 4.3e-35 117.0 0.0 0.00044 20.2 0.3 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 EGG22729.1 - 1.8e-33 113.0 0.0 4.1e-05 23.2 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGG22729.1 - 1.1e-29 100.1 0.0 0.00053 20.0 0.0 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 EGG22729.1 - 5.1e-29 100.6 0.3 6e-06 26.8 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGG22729.1 - 1.2e-28 97.4 1.5 0.0027 18.4 0.0 8.4 2 2 6 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 EGG22729.1 - 2.1e-25 89.0 2.2 5.3e-06 26.9 0.0 5.5 3 1 1 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGG22729.1 - 5e-21 74.1 5.9 0.00055 19.6 0.0 8.0 5 1 3 8 8 8 6 TPR repeat TPR_7 PF13176.6 EGG22729.1 - 1.7e-20 71.5 8.0 0.0055 16.7 1.2 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGG22729.1 - 2.1e-19 69.6 8.0 1.4e-06 28.4 0.9 6.4 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_9 PF13371.6 EGG22729.1 - 6.6e-18 64.6 1.1 0.0012 18.9 0.0 4.9 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_6 PF13174.6 EGG22729.1 - 6.5e-16 57.8 0.2 1.1 10.0 0.3 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG22729.1 - 2.4e-14 53.3 2.5 0.0012 19.1 0.0 4.7 4 1 0 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGG22729.1 - 1.7e-12 46.8 2.8 0.069 13.6 0.0 7.2 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGG22729.1 - 7.7e-09 35.2 0.3 4.7e-06 26.0 0.4 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 EGG22729.1 - 1.3e-07 32.1 0.1 0.12 12.8 0.0 3.7 2 2 2 4 4 4 2 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 EGG22729.1 - 2.1e-06 27.7 0.5 1 9.5 0.0 4.8 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 EGG22729.1 - 2.4e-06 26.8 1.8 0.0012 17.8 0.1 3.0 1 1 2 3 3 3 2 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 EGG22729.1 - 3.5e-06 26.7 12.1 5.9 6.9 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGG22729.1 - 3.9e-05 23.2 0.2 0.13 11.6 0.0 3.9 2 1 0 3 3 3 1 MalT-like TPR region PknG_TPR PF16918.5 EGG22729.1 - 0.00027 19.8 0.1 0.00098 17.9 0.1 1.9 1 1 1 2 2 2 1 Protein kinase G tetratricopeptide repeat TPR_21 PF09976.9 EGG22729.1 - 0.00035 20.4 0.7 1.2 8.8 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat-like domain Alkyl_sulf_dimr PF14863.6 EGG22729.1 - 0.00094 19.7 0.3 4.4 7.7 0.0 4.0 3 1 1 4 4 4 1 Alkyl sulfatase dimerisation RPN7 PF10602.9 EGG22729.1 - 0.015 15.0 0.4 7.2 6.3 0.0 4.1 2 1 3 5 5 4 0 26S proteasome subunit RPN7 HLH PF00010.26 EGG22729.1 - 0.017 15.0 0.1 0.046 13.7 0.1 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain ANAPC5 PF12862.7 EGG22729.1 - 0.031 14.4 1.5 1.8 8.6 0.1 3.8 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_20 PF14561.6 EGG22729.1 - 0.084 13.2 2.9 32 5.0 0.0 4.5 4 2 3 7 7 5 0 Tetratricopeptide repeat Dickkopf_N PF04706.12 EGG22730.1 - 0.037 14.5 7.6 0.037 14.5 7.6 7.2 4 2 2 6 6 6 0 Dickkopf N-terminal cysteine-rich region EB PF01683.18 EGG22730.1 - 0.043 14.1 1.9 0.043 14.1 1.9 7.4 2 2 5 8 8 8 0 EB module UDG PF03167.19 EGG22731.1 - 2.9e-22 79.3 0.1 4.2e-22 78.8 0.1 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sipho_tail PF05709.11 EGG22731.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Phage tail protein NigD_N PF12667.7 EGG22731.1 - 0.15 12.2 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 NigD-like N-terminal OB domain Cid2 PF09774.9 EGG22732.1 - 8.8e-06 26.2 4.2 0.0037 17.7 1.4 2.1 1 1 1 2 2 2 2 Caffeine-induced death protein 2 Glyco_hydro_65m PF03632.15 EGG22732.1 - 0.01 14.7 1.0 0.011 14.6 1.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain DEK_C PF08766.11 EGG22732.1 - 0.025 14.5 0.2 2.7 8.0 0.1 2.9 2 1 1 3 3 3 0 DEK C terminal domain DUF836 PF05768.14 EGG22733.1 - 7.2e-07 29.5 0.1 1.3e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EGG22733.1 - 0.022 15.0 0.1 0.045 14.0 0.1 1.6 1 1 0 1 1 1 0 Glutaredoxin MS_channel PF00924.18 EGG22733.1 - 0.1 12.1 1.4 0.11 12.0 1.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel LIM PF00412.22 EGG22734.1 - 1.9e-34 117.7 46.7 8.8e-12 45.1 3.0 5.2 5 0 0 5 5 5 5 LIM domain PSCyt3 PF07627.11 EGG22734.1 - 0.29 11.4 0.1 0.29 11.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1588) Kinesin PF00225.23 EGG22735.1 - 2.1e-87 293.2 12.1 2.1e-87 293.2 12.1 3.5 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EGG22735.1 - 4.6e-16 59.1 0.2 4.6e-16 59.1 0.2 4.0 3 1 1 4 4 4 2 Microtubule binding UPF0052 PF01933.18 EGG22736.1 - 0.11 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Ank_2 PF12796.7 EGG22737.1 - 2.5e-05 24.8 0.1 6.8e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG22737.1 - 0.0031 17.9 0.0 0.25 12.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGG22737.1 - 0.023 15.3 0.0 0.05 14.2 0.0 1.6 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22737.1 - 0.03 14.7 0.0 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) EF-hand_7 PF13499.6 EGG22738.1 - 1.7e-06 28.4 0.4 5e-06 26.9 0.2 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGG22738.1 - 3.8e-05 23.3 0.5 0.00055 19.7 0.2 2.6 1 1 1 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGG22738.1 - 4.8e-05 22.6 4.2 0.00072 18.9 0.3 3.1 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 EGG22738.1 - 0.00015 21.1 0.5 0.00042 19.7 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 EGG22738.1 - 0.0004 20.7 0.4 0.00085 19.6 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain YabA PF06156.13 EGG22739.1 - 0.018 15.6 0.7 0.13 12.9 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 EGG22739.1 - 0.021 15.3 1.4 0.021 15.3 1.4 1.9 2 0 0 2 2 2 0 Cell division protein ZapB CENP-Q PF13094.6 EGG22739.1 - 0.059 13.6 0.2 0.059 13.6 0.2 2.5 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit LRR19-TM PF15176.6 EGG22739.1 - 0.093 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain PsbN PF02468.15 EGG22739.1 - 2.8 7.9 4.2 0.66 9.9 0.1 2.0 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) DUF4718 PF15842.5 EGG22739.1 - 5.6 6.7 11.3 5.6 6.7 5.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4718) DivIC PF04977.15 EGG22739.1 - 9.9 6.0 6.4 1.2 8.9 1.8 1.9 2 0 0 2 2 2 0 Septum formation initiator GIY-YIG PF01541.24 EGG22740.1 - 1.7e-08 34.6 0.3 1.2e-07 31.9 0.0 2.7 3 0 0 3 3 3 1 GIY-YIG catalytic domain PhyH PF05721.13 EGG22741.1 - 3.8e-28 99.2 0.0 5.1e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Nop53 PF07767.11 EGG22742.1 - 3.7e-27 95.7 49.9 6e-27 95.1 49.9 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) ATP_bind_1 PF03029.17 EGG22743.1 - 1.8e-88 296.4 0.3 2e-88 296.2 0.3 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EGG22743.1 - 0.00055 19.5 0.1 0.0087 15.6 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CLP1_P PF16575.5 EGG22743.1 - 0.00081 19.2 0.0 0.024 14.4 0.0 2.5 2 1 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_29 PF13555.6 EGG22743.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EGG22743.1 - 0.0017 18.1 0.0 0.0026 17.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 EGG22743.1 - 0.0019 17.9 0.2 0.81 9.4 0.2 2.6 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 EGG22743.1 - 0.0087 16.6 0.1 0.028 15.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGG22743.1 - 0.0097 15.8 0.2 6.1 6.7 0.0 2.9 2 1 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EGG22743.1 - 0.023 15.1 0.0 0.095 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 EGG22743.1 - 0.092 12.0 0.0 1.5 8.0 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin SMC_N PF02463.19 EGG22743.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGG22743.1 - 0.15 12.3 0.0 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EGG22743.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 EGG22743.1 - 0.16 11.5 0.0 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Ank_2 PF12796.7 EGG22744.1 - 1.5e-10 41.5 0.1 0.015 15.9 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22744.1 - 4.4e-05 24.0 0.7 45 4.8 0.0 5.8 5 1 0 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22744.1 - 4.6e-05 23.5 0.2 7.5 7.5 0.0 6.2 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EGG22744.1 - 0.0017 18.6 0.1 45 4.5 0.0 4.8 3 2 2 5 5 5 0 Ankyrin repeats (many copies) DUF2179 PF10035.9 EGG22744.1 - 0.032 14.0 0.5 0.095 12.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) CD36 PF01130.21 EGG22745.1 - 5.1e-57 193.4 7.6 2.1e-31 109.0 0.1 2.2 2 0 0 2 2 2 2 CD36 family PorA PF11271.8 EGG22745.1 - 0.0043 16.4 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 2 Porin PorA SR-25 PF10500.9 EGG22746.1 - 0.0058 16.3 10.3 0.0058 16.3 10.3 3.2 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein DUF3439 PF11921.8 EGG22746.1 - 0.48 10.4 11.7 0.89 9.5 11.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ank_2 PF12796.7 EGG22748.1 - 7.1e-29 100.2 0.1 1.9e-13 50.8 0.0 4.1 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22748.1 - 4.4e-23 81.4 0.0 0.0003 21.3 0.0 5.3 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22748.1 - 2.9e-22 78.4 0.2 7.2e-09 35.7 0.0 6.3 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22748.1 - 3.1e-19 67.0 0.0 0.0015 18.9 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 EGG22748.1 - 3.5e-18 65.1 0.2 0.00038 20.8 0.0 7.5 8 0 0 8 8 8 3 Ankyrin repeat Patatin PF01734.22 EGG22749.1 - 3e-11 43.9 0.0 5.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase MMR_HSR1 PF01926.23 EGG22749.1 - 0.043 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-RING_UBOX PF13445.6 EGG22749.1 - 0.3 11.2 12.1 0.99 9.5 12.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 EGG22749.1 - 2 8.4 6.3 5.5 6.9 6.3 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ABC_tran PF00005.27 EGG22750.1 - 0.0085 16.6 0.0 0.055 14.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter zf-RING_10 PF16685.5 EGG22750.1 - 0.016 15.3 8.3 0.016 15.3 8.3 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 MMR_HSR1 PF01926.23 EGG22750.1 - 0.03 14.4 0.0 0.079 13.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 EGG22750.1 - 0.04 14.5 0.2 1.7 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGG22750.1 - 0.079 12.9 0.1 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 EGG22750.1 - 0.1 13.0 0.0 1 9.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Prok-RING_4 PF14447.6 EGG22750.1 - 0.12 12.3 11.4 0.48 10.3 11.4 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TusA PF01206.17 EGG22750.1 - 0.13 12.1 0.1 0.38 10.6 0.1 1.9 1 0 0 1 1 1 0 Sulfurtransferase TusA Telomere_reg-2 PF10193.9 EGG22750.1 - 0.29 11.6 1.5 0.42 11.1 0.2 1.9 2 0 0 2 2 2 0 Telomere length regulation protein zf-RING_5 PF14634.6 EGG22750.1 - 3 7.9 22.5 0.021 14.8 11.3 2.6 2 0 0 2 2 2 0 zinc-RING finger domain SNARE_assoc PF09335.11 EGG22751.1 - 1.1e-30 106.6 4.6 1.1e-30 106.6 4.6 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF1772 PF08592.11 EGG22751.1 - 0.022 15.1 4.7 0.17 12.2 0.1 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF1772) NAD4L PF06235.11 EGG22751.1 - 0.024 14.6 0.3 0.024 14.6 0.3 2.7 3 0 0 3 3 3 0 NADH dehydrogenase subunit 4L (NAD4L) MAP17 PF15807.5 EGG22751.1 - 0.031 14.5 3.0 0.59 10.4 1.6 2.5 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4577 PF15145.6 EGG22751.1 - 0.065 13.3 1.5 7.2 6.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) DUF92 PF01940.16 EGG22751.1 - 3 7.2 6.4 0.9 8.9 1.5 2.3 1 1 0 2 2 2 0 Integral membrane protein DUF92 TssN PF17555.2 EGG22751.1 - 4.2 6.7 8.3 0.44 9.9 2.9 2.1 1 1 1 2 2 2 0 Type VI secretion system, TssN 7tm_2 PF00002.24 EGG22753.1 - 3.3e-27 95.3 16.4 4.1e-27 95.0 16.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 EGG22753.1 - 6.6e-21 74.7 16.0 7.9e-21 74.5 16.0 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Frizzled PF01534.17 EGG22753.1 - 7.4e-11 41.7 20.0 3.3e-06 26.4 6.8 2.2 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region Ocular_alb PF02101.15 EGG22753.1 - 2e-09 36.9 5.4 3.1e-09 36.2 4.5 1.7 2 0 0 2 2 2 1 Ocular albinism type 1 protein PRP1_N PF06424.12 EGG22756.1 - 0.0019 18.6 1.4 0.0019 18.6 1.4 1.2 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TCP PF03634.13 EGG22756.1 - 0.023 15.3 10.2 0.032 14.8 10.2 1.1 1 0 0 1 1 1 0 TCP family transcription factor DUF3984 PF13136.6 EGG22756.1 - 0.35 10.2 16.3 0.43 9.9 16.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) CCSAP PF15748.5 EGG22756.1 - 1 9.5 14.2 1.4 9.1 14.2 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF719 PF05334.13 EGG22756.1 - 1.4 9.1 10.9 1.9 8.7 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Presenilin PF01080.17 EGG22756.1 - 2 7.1 8.2 2.5 6.8 8.2 1.2 1 0 0 1 1 1 0 Presenilin CAP_N PF01213.19 EGG22756.1 - 2.8 7.4 15.7 0.73 9.3 7.6 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pannexin_like PF12534.8 EGG22756.1 - 3.1 6.8 11.4 1 8.4 8.7 1.5 1 1 1 2 2 2 0 Pannexin-like TM region of LRRC8 FAM176 PF14851.6 EGG22756.1 - 3.6 7.2 7.8 2.1 8.0 5.9 1.5 1 1 1 2 2 2 0 FAM176 family CSG2 PF16965.5 EGG22756.1 - 4.7 6.1 9.0 5.7 5.8 9.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Pap_E4 PF02711.14 EGG22756.1 - 6 7.9 24.5 1.4 9.9 9.5 2.2 1 1 1 2 2 2 0 E4 protein Inp1 PF12634.7 EGG22756.1 - 8.1 6.5 9.8 2.7 8.0 2.1 2.1 2 0 0 2 2 2 0 Inheritance of peroxisomes protein 1 Dynamin_N PF00350.23 EGG22757.1 - 9.5e-21 74.6 2.5 1.5e-17 64.2 0.0 2.7 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 EGG22757.1 - 1.6e-06 28.2 0.0 9.5e-06 25.7 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase GNAT_acetyltr_2 PF13718.6 EGG22757.1 - 0.066 12.6 1.4 0.15 11.5 1.4 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase 2 AAA_16 PF13191.6 EGG22757.1 - 0.1 13.0 0.4 1.1 9.6 0.0 3.0 4 0 0 4 4 4 0 AAA ATPase domain PBP_sp32 PF07222.12 EGG22757.1 - 0.53 9.7 9.7 0.93 8.9 9.7 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 AAA_23 PF13476.6 EGG22757.1 - 0.8 10.2 20.3 3.1 8.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EGG22757.1 - 4.3 7.0 28.1 0.2 11.3 2.7 3.5 2 1 1 3 3 3 0 AAA ATPase domain DUF4484 PF14831.6 EGG22757.1 - 5.9 6.9 8.6 46 4.0 7.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Dicty_CAR PF05462.11 EGG22760.1 - 2.1e-09 37.0 8.9 2.1e-09 37.0 8.9 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Fz PF01392.22 EGG22760.1 - 0.00064 20.3 3.6 0.00064 20.3 3.6 2.1 2 0 0 2 2 2 1 Fz domain Frizzled PF01534.17 EGG22760.1 - 0.0067 15.5 10.5 0.022 13.8 10.5 1.8 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 EGG22760.1 - 0.11 11.8 6.1 0.18 11.1 6.1 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) DHHC PF01529.20 EGG22760.1 - 1 9.5 16.2 0.84 9.7 1.1 3.8 3 1 1 4 4 4 0 DHHC palmitoyltransferase TGT PF01702.18 EGG22762.1 - 8.7e-97 324.4 0.1 2.5e-70 237.4 0.0 2.1 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase 3Beta_HSD PF01073.19 EGG22763.1 - 2.3e-67 227.0 0.0 2.9e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGG22763.1 - 8.9e-33 113.7 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG22763.1 - 1.1e-17 64.4 0.0 2.5e-14 53.4 0.0 2.3 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGG22763.1 - 9.2e-13 47.9 0.0 2.3e-08 33.6 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EGG22763.1 - 3.7e-12 46.5 0.0 5.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGG22763.1 - 3.7e-09 36.1 0.0 1.6e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGG22763.1 - 3e-08 33.1 0.0 3.9e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EGG22763.1 - 1.9e-05 24.6 0.6 0.0042 17.0 0.6 2.4 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EGG22763.1 - 0.00038 20.1 0.0 0.00068 19.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EGG22763.1 - 0.014 15.7 0.1 0.037 14.3 0.1 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Arf PF00025.21 EGG22764.1 - 5.3e-64 214.9 0.6 6.5e-64 214.6 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG22764.1 - 1.3e-13 51.2 0.1 2.3e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG22764.1 - 1.5e-13 50.7 0.0 2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EGG22764.1 - 1.4e-10 40.9 2.1 2.6e-07 30.1 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGG22764.1 - 5.4e-09 35.7 0.0 7.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGG22764.1 - 3.7e-08 33.0 0.0 4.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGG22764.1 - 6.9e-07 29.4 0.0 1.7e-06 28.1 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG22764.1 - 0.00066 19.3 0.0 0.0011 18.6 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Prophage_tail PF06605.11 EGG22764.1 - 0.006 15.8 0.2 0.0088 15.3 0.2 1.2 1 0 0 1 1 1 1 Prophage endopeptidase tail MeaB PF03308.16 EGG22764.1 - 0.019 14.0 0.2 0.039 12.9 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 EGG22764.1 - 0.13 11.8 1.0 0.44 10.1 0.2 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B Transglut_core PF01841.19 EGG22765.1 - 1.6e-31 109.1 0.2 3.7e-15 56.3 0.1 2.7 2 0 0 2 2 2 2 Transglutaminase-like superfamily Kinase-PPPase PF03618.14 EGG22765.1 - 0.0041 16.9 0.5 0.33 10.7 0.1 2.3 2 0 0 2 2 2 2 Kinase/pyrophosphorylase RNase_H2-Ydr279 PF09468.10 EGG22765.1 - 0.0045 17.2 2.1 0.71 10.0 0.1 3.0 3 0 0 3 3 3 2 Ydr279p protein family (RNase H2 complex component) wHTH domain HigB-like_toxin PF05015.13 EGG22765.1 - 0.56 10.6 4.2 13 6.2 0.3 2.6 2 0 0 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB FecR PF04773.13 EGG22766.1 - 0.049 14.3 0.3 0.93 10.2 0.0 3.1 2 1 1 3 3 3 0 FecR protein Ras PF00071.22 EGG22767.1 - 4.6e-10 39.3 0.0 3.2e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 Ras family LRR_8 PF13855.6 EGG22768.1 - 0.0025 17.6 7.3 0.089 12.6 4.3 4.1 3 1 0 3 3 3 1 Leucine rich repeat FNIP PF05725.12 EGG22768.1 - 0.023 14.8 0.2 0.13 12.4 0.2 2.4 1 0 0 1 1 1 0 FNIP Repeat LRR_1 PF00560.33 EGG22768.1 - 0.12 13.0 1.8 1e+02 4.1 0.0 5.4 3 0 0 3 3 3 0 Leucine Rich Repeat DUF3844 PF12955.7 EGG22768.1 - 1 9.5 6.9 1.5 9.0 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) LRR_4 PF12799.7 EGG22768.1 - 2.5 8.7 19.6 0.093 13.2 1.4 5.7 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Ras PF00071.22 EGG22769.1 - 1e-10 41.4 0.3 2.7e-10 40.1 0.3 1.7 1 0 0 1 1 1 1 Ras family Ank_5 PF13857.6 EGG22769.1 - 0.058 13.7 0.0 0.37 11.2 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ribosomal_L27e PF01777.18 EGG22769.1 - 0.096 13.0 0.2 0.69 10.3 0.0 2.5 2 0 0 2 2 2 0 Ribosomal L27e protein family Staph_haemo PF05480.11 EGG22770.1 - 0.016 15.0 0.2 0.43 10.4 0.0 2.5 2 0 0 2 2 2 0 Staphylococcus haemolytic protein YtpI PF14007.6 EGG22770.1 - 0.14 12.3 6.7 1 9.5 0.0 2.8 2 1 0 2 2 2 0 YtpI-like protein Nckap1 PF09735.9 EGG22771.1 - 0.027 12.5 0.1 1.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Membrane-associated apoptosis protein DUF3134 PF11332.8 EGG22771.1 - 0.15 12.4 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) Ank_2 PF12796.7 EGG22772.1 - 2.3e-22 79.4 13.6 7.6e-06 26.4 0.2 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22772.1 - 8.1e-17 61.1 8.9 0.0014 18.9 0.0 8.6 2 1 8 10 10 10 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22772.1 - 1.6e-14 54.0 4.7 0.0056 17.2 0.1 6.2 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22772.1 - 7.9e-12 44.3 0.5 3.7 8.4 0.0 8.8 8 1 1 9 9 9 1 Ankyrin repeat DUF5049 PF16468.5 EGG22772.1 - 4.9e-05 23.1 0.4 16 5.5 0.0 5.8 3 1 3 6 6 6 1 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22772.1 - 6.1e-05 23.3 2.4 44 4.8 0.0 6.5 3 3 3 6 6 6 0 Ankyrin repeat Acetyltransf_14 PF03421.16 EGG22772.1 - 0.00047 20.3 0.1 0.21 11.6 0.0 2.4 1 1 1 2 2 2 2 YopJ Serine/Threonine acetyltransferase ZNRF_3_ecto PF18212.1 EGG22772.1 - 0.058 13.4 0.0 0.46 10.5 0.0 2.4 3 0 0 3 3 3 0 ZNRF-3 Ectodomain WD40 PF00400.32 EGG22775.1 - 6.7e-32 109.0 8.1 4.7e-05 24.1 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG22775.1 - 0.0037 17.5 0.0 1.6 9.1 0.0 3.7 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain LRR_8 PF13855.6 EGG22777.1 - 3.4e-19 68.3 54.5 1.3e-06 28.1 5.3 8.8 6 3 2 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 EGG22777.1 - 9e-17 60.9 64.1 0.00025 21.4 4.0 10.7 8 2 3 11 11 11 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGG22777.1 - 4.5e-13 49.1 31.2 9.6e-06 25.2 1.4 6.0 5 2 1 6 6 6 4 Leucine-rich repeat DUF1319 PF07028.11 EGG22777.1 - 0.15 12.3 1.0 71 3.7 0.1 4.0 3 2 1 4 4 4 0 Protein of unknown function (DUF1319) LRR_6 PF13516.6 EGG22777.1 - 0.45 10.7 33.8 5.7 7.3 0.1 9.5 12 1 0 12 12 12 0 Leucine Rich repeat SR-25 PF10500.9 EGG22777.1 - 2.4 7.7 3.8 25 4.4 0.4 2.7 3 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein ELP6 PF09807.9 EGG22778.1 - 9e-32 110.5 4.1 2.5e-29 102.5 4.1 2.5 1 1 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 EGG22778.1 - 1.3e-05 24.9 3.1 0.0003 20.4 3.1 2.4 1 1 0 1 1 1 1 Elongator subunit Iki1 ABC_tran PF00005.27 EGG22779.1 - 2.9e-54 183.3 0.6 1e-25 90.8 0.0 3.2 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EGG22779.1 - 2.5e-18 66.9 7.9 2.3e-05 24.4 0.0 4.7 4 1 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG22779.1 - 1.4e-10 41.0 1.9 0.056 12.9 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 EGG22779.1 - 3e-10 40.0 14.5 4.2e-10 39.5 2.4 2.9 3 0 0 3 3 2 2 ABC transporter MMR_HSR1 PF01926.23 EGG22779.1 - 4.3e-07 30.0 0.1 0.018 15.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EGG22779.1 - 1.2e-06 28.1 3.9 0.0055 16.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 EGG22779.1 - 3.2e-06 27.7 4.6 0.0058 17.2 0.3 3.6 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EGG22779.1 - 1.3e-05 25.2 1.4 0.051 13.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 EGG22779.1 - 9.7e-05 22.8 0.1 0.54 10.7 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGG22779.1 - 0.00014 22.2 0.4 0.91 9.7 0.1 2.8 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EGG22779.1 - 0.00021 21.4 1.0 0.012 15.6 0.0 3.1 3 0 0 3 3 3 1 Dynamin family AAA_23 PF13476.6 EGG22779.1 - 0.0011 19.5 0.0 0.0011 19.5 0.0 4.8 4 1 1 5 5 5 2 AAA domain AAA_33 PF13671.6 EGG22779.1 - 0.0015 18.7 2.1 0.63 10.2 0.1 3.0 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.6 EGG22779.1 - 0.0015 18.3 0.3 1.1 8.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGG22779.1 - 0.0016 18.8 0.1 3 8.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase MeaB PF03308.16 EGG22779.1 - 0.0019 17.2 0.5 0.86 8.5 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EGG22779.1 - 0.0021 18.5 3.3 0.28 11.5 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EGG22779.1 - 0.0022 17.2 0.1 1.1 8.4 0.1 2.4 2 0 0 2 2 2 2 NB-ARC domain SbcCD_C PF13558.6 EGG22779.1 - 0.0039 17.4 1.2 6.6 7.0 0.1 4.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 EGG22779.1 - 0.0045 17.0 0.3 6 6.9 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.6 EGG22779.1 - 0.0095 16.2 4.7 0.34 11.2 0.2 3.4 2 2 0 2 2 2 1 AAA domain Roc PF08477.13 EGG22779.1 - 0.014 15.6 0.3 4.6 7.5 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 EGG22779.1 - 0.021 14.9 6.4 0.42 10.7 0.4 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_5 PF07728.14 EGG22779.1 - 0.024 14.6 0.2 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CLP1_P PF16575.5 EGG22779.1 - 0.028 14.2 0.3 7.6 6.3 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Cytidylate_kin PF02224.18 EGG22779.1 - 0.075 12.8 0.2 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase KAP_NTPase PF07693.14 EGG22779.1 - 0.075 12.2 4.1 1.3 8.2 0.0 3.0 3 1 0 3 3 3 0 KAP family P-loop domain AAA_30 PF13604.6 EGG22779.1 - 0.08 12.6 0.7 12 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EGG22779.1 - 0.12 12.2 0.3 17 5.2 0.1 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 EGG22779.1 - 0.13 12.2 0.8 3.8 7.4 0.1 2.8 2 1 0 2 2 2 0 NTPase PRK PF00485.18 EGG22779.1 - 0.18 11.5 1.2 11 5.7 0.1 2.9 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 EGG22779.1 - 0.2 11.6 7.2 4.3 7.2 0.1 3.1 3 0 0 3 3 3 0 NACHT domain ATP_bind_1 PF03029.17 EGG22779.1 - 0.22 11.3 0.5 13 5.5 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EGG22779.1 - 0.25 11.1 1.3 5 6.9 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 EGG22779.1 - 0.27 10.5 3.3 11 5.3 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.6 EGG22779.1 - 0.31 10.6 1.3 35 3.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 EGG22779.1 - 0.78 10.2 5.2 4.8 7.6 0.1 3.0 3 0 0 3 3 2 0 AAA domain AAA_13 PF13166.6 EGG22779.1 - 0.86 8.2 10.1 4 6.0 0.1 3.6 4 0 0 4 4 3 0 AAA domain SRPRB PF09439.10 EGG22779.1 - 4.4 6.7 7.2 0.65 9.4 0.1 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DEAD PF00270.29 EGG22780.1 - 5.2e-11 42.6 0.2 7.4e-11 42.1 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 EGG22780.1 - 0.22 11.8 0.0 0.32 11.2 0.0 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Ank_2 PF12796.7 EGG22781.1 - 1.1e-07 32.3 0.1 0.02 15.5 0.0 3.9 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22781.1 - 7.8e-07 29.5 1.9 0.35 11.5 0.0 6.2 6 2 0 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22781.1 - 3.9e-06 27.0 0.3 0.74 10.2 0.0 4.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22781.1 - 3e-05 24.1 4.2 0.21 12.3 0.0 7.0 8 1 0 8 8 8 1 Ankyrin repeat FOP_dimer PF09398.10 EGG22783.1 - 0.047 14.0 0.5 0.15 12.3 0.5 1.8 1 0 0 1 1 1 0 FOP N terminal dimerisation domain BSP_II PF05432.11 EGG22785.1 - 0.0017 18.1 6.3 0.0017 18.1 6.3 1.9 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 EGG22785.1 - 0.0028 16.0 2.6 0.0059 14.9 2.6 1.4 1 0 0 1 1 1 1 Nop14-like family Ank_2 PF12796.7 EGG22785.1 - 0.003 18.1 1.6 15 6.3 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG22785.1 - 0.0043 17.5 0.3 84 4.3 0.0 5.6 5 0 0 5 5 5 0 Ankyrin repeat Senescence PF06911.12 EGG22786.1 - 1.9e-31 109.8 6.0 1.9e-31 109.8 6.0 1.6 2 0 0 2 2 2 1 Senescence-associated protein PH PF00169.29 EGG22786.1 - 5e-06 27.0 0.0 2e-05 25.0 0.0 2.0 1 0 0 1 1 1 1 PH domain DUF3597 PF12200.8 EGG22786.1 - 4.2 7.9 9.6 2.3 8.8 4.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) HLH PF00010.26 EGG22787.1 - 0.0005 20.0 2.6 0.0014 18.5 2.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BSP_II PF05432.11 EGG22787.1 - 0.012 15.4 8.4 0.012 15.4 8.4 3.9 2 1 1 3 3 3 0 Bone sialoprotein II (BSP-II) Tfb4 PF03850.14 EGG22788.1 - 1.6e-84 283.7 10.1 2.3e-84 283.2 10.1 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 Ras PF00071.22 EGG22791.1 - 6.9e-15 55.0 3.7 3.3e-14 52.8 3.7 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG22791.1 - 1.9e-08 34.5 0.2 8e-08 32.5 0.2 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 EGG22791.1 - 0.0061 16.0 2.5 0.025 14.0 0.0 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein Arf PF00025.21 EGG22791.1 - 0.0063 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family EPO_TPO PF00758.18 EGG22791.1 - 0.039 14.0 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin NACHT PF05729.12 EGG22791.1 - 0.054 13.4 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 NACHT domain DUF1908 PF08926.11 EGG22791.1 - 0.06 12.4 0.2 0.12 11.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) PduV-EutP PF10662.9 EGG22791.1 - 0.09 12.5 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EGG22791.1 - 0.096 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 EGG22791.1 - 0.16 11.9 0.0 0.46 10.5 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EGG22791.1 - 0.18 12.1 0.2 1.7 8.9 0.1 2.8 1 1 1 2 2 2 0 AAA domain Ras PF00071.22 EGG22792.1 - 1.2e-13 50.9 1.0 2.6e-13 49.9 0.4 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG22792.1 - 1.7e-13 50.8 0.1 1.7e-13 50.8 0.1 2.2 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGG22792.1 - 4.2e-05 23.6 0.2 0.00026 21.0 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 EGG22792.1 - 0.00084 18.8 1.4 0.0017 17.8 0.1 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF685 PF05085.12 EGG22792.1 - 0.0032 16.8 4.1 0.0032 16.8 4.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF685) FeoB_N PF02421.18 EGG22792.1 - 0.0041 16.7 0.0 0.0077 15.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 EGG22792.1 - 0.0065 16.8 0.1 0.028 14.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EGG22792.1 - 0.021 14.8 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EGG22792.1 - 0.031 14.2 0.3 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 EGG22792.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Glyco_hydro_88 PF07470.13 EGG22795.1 - 0.013 14.6 0.1 0.015 14.4 0.1 1.0 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Ank_2 PF12796.7 EGG22795.1 - 0.021 15.4 0.4 0.14 12.7 0.1 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Claudin_3 PF06653.11 EGG22797.1 - 0.00011 22.2 1.9 0.00011 22.2 1.9 1.7 2 0 0 2 2 2 1 Tight junction protein, Claudin-like DUF1980 PF09323.10 EGG22797.1 - 0.011 15.7 3.4 0.012 15.5 0.3 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF1980) HKR_ArcB_TM PF18415.1 EGG22797.1 - 0.53 11.1 4.5 1.1 10.2 0.0 2.9 3 1 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain DUF3488 PF11992.8 EGG22797.1 - 1.5 7.7 4.1 0.87 8.5 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) Piwi PF02171.17 EGG22798.1 - 8.7e-67 225.5 0.1 1.4e-66 224.8 0.1 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 EGG22798.1 - 1.9e-21 76.3 0.7 4.3e-21 75.2 0.7 1.6 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 EGG22798.1 - 0.00032 20.3 0.0 0.0008 19.0 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain DUF4683 PF15735.5 EGG22798.1 - 0.17 11.4 1.9 0.28 10.8 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) Sporozoite_P67 PF05642.11 EGG22798.1 - 0.23 9.5 14.0 0.32 9.0 14.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hamartin PF04388.12 EGG22798.1 - 1.4 7.5 7.1 2 7.0 7.1 1.1 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.25 EGG22802.1 - 4.2e-14 52.5 0.0 1.1e-07 31.6 0.0 3.0 1 1 1 2 2 2 2 Protein kinase domain Macoilin PF09726.9 EGG22802.1 - 2 6.9 27.5 3.1 6.3 27.5 1.2 1 0 0 1 1 1 0 Macoilin family DUF3153 PF11353.8 EGG22803.1 - 0.00027 20.6 1.1 0.0022 17.6 0.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3153) MIEAP PF16026.5 EGG22803.1 - 0.0007 19.9 3.5 0.0028 17.9 0.1 2.3 2 0 0 2 2 2 1 Mitochondria-eating protein CAP_N PF01213.19 EGG22803.1 - 0.1 12.1 2.3 0.086 12.3 0.6 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal HSP70 PF00012.20 EGG22804.1 - 0.0004 18.7 0.0 0.0023 16.2 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein HSP70 PF00012.20 EGG22805.1 - 0.0066 14.7 0.1 0.0081 14.4 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein DENN PF02141.21 EGG22806.1 - 3.5e-30 105.3 3.7 5.5e-29 101.4 0.0 3.6 3 1 1 4 4 4 1 DENN (AEX-3) domain uDENN PF03456.18 EGG22806.1 - 2.9e-07 31.1 2.8 2.9e-07 31.1 2.8 2.4 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 EGG22806.1 - 6.3e-05 22.9 4.5 0.00024 21.0 4.5 2.0 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 EGG22806.1 - 0.014 15.4 0.8 0.04 13.9 0.2 2.1 2 0 0 2 2 2 0 Stabilization of polarity axis SUIM_assoc PF16619.5 EGG22806.1 - 2.3 8.3 30.4 0.17 12.0 3.0 4.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Cwf_Cwc_15 PF04889.12 EGG22807.1 - 4e-40 138.1 74.8 4e-37 128.3 74.8 2.2 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Cellulase PF00150.18 EGG22808.1 - 8.3e-35 120.6 7.8 1.4e-34 119.8 7.8 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ras PF00071.22 EGG22810.1 - 1.7e-13 50.5 0.5 2.1e-07 30.7 0.1 2.5 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGG22810.1 - 3.8e-12 46.5 0.6 2e-07 31.2 0.0 3.5 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG22810.1 - 0.00033 20.2 2.3 0.94 8.9 0.0 3.4 3 0 0 3 3 3 2 ADP-ribosylation factor family DUF3446 PF11928.8 EGG22810.1 - 0.0018 18.5 3.7 0.0018 18.5 3.7 6.8 4 1 2 6 6 6 1 Early growth response N-terminal domain Ank_2 PF12796.7 EGG22812.1 - 1.9e-10 41.2 3.7 0.00023 21.7 0.3 5.9 4 2 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG22812.1 - 1.3e-07 32.0 0.8 0.045 14.3 0.0 6.9 6 1 0 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22812.1 - 0.00013 22.1 2.2 2.2e+02 3.0 0.0 8.4 10 1 1 11 11 11 0 Ankyrin repeat Ank_5 PF13857.6 EGG22812.1 - 0.057 13.8 5.6 8.1 6.9 0.0 4.9 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Polo_box_3 PF18544.1 EGG22812.1 - 0.087 13.5 0.7 0.28 11.8 0.1 2.3 2 0 0 2 2 2 0 Polo box domain Ras PF00071.22 EGG22813.1 - 7.9e-61 204.4 0.0 9.4e-61 204.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG22813.1 - 4.7e-32 110.7 0.0 1.1e-31 109.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG22813.1 - 7.5e-11 41.8 0.0 9.3e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG22813.1 - 0.00019 21.5 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG22813.1 - 0.00058 19.8 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGG22813.1 - 0.0062 15.9 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGG22813.1 - 0.0079 15.8 0.0 0.041 13.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DAP3 PF10236.9 EGG22813.1 - 0.049 12.8 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 EGG22813.1 - 0.076 13.3 0.1 0.32 11.3 0.0 2.0 1 1 0 2 2 2 0 AAA domain 3HCDH_N PF02737.18 EGG22814.1 - 8.4e-60 201.7 5.8 1.1e-59 201.4 5.8 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGG22814.1 - 4.2e-36 123.5 0.0 9.6e-36 122.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain TrkA_N PF02254.18 EGG22814.1 - 1.1e-05 25.6 1.2 0.00013 22.2 0.2 2.3 1 1 1 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EGG22814.1 - 2.5e-05 24.5 1.0 5.3e-05 23.5 1.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EGG22814.1 - 5.6e-05 23.4 2.0 0.00014 22.1 2.0 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGG22814.1 - 0.00013 22.5 0.9 0.00036 21.1 0.8 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGG22814.1 - 0.00027 21.0 4.0 0.00092 19.3 1.3 2.5 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 EGG22814.1 - 0.00074 18.8 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EGG22814.1 - 0.00081 19.1 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EGG22814.1 - 0.0011 18.3 0.5 0.0028 17.0 0.2 1.7 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2680 PF10925.8 EGG22814.1 - 0.0027 17.6 1.2 0.31 11.1 0.7 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2680) Pyr_redox PF00070.27 EGG22814.1 - 0.0038 17.7 0.5 0.0094 16.5 0.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EGG22814.1 - 0.0086 16.1 1.7 0.019 15.0 1.4 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 EGG22814.1 - 0.011 15.3 1.0 0.019 14.6 1.0 1.4 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 EGG22814.1 - 0.056 13.9 0.3 0.093 13.2 0.3 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding TPR_1 PF00515.28 EGG22816.1 - 1.9e-18 65.4 2.9 2.3e-06 27.2 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG22816.1 - 1.2e-14 53.2 0.4 0.00064 19.6 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGG22816.1 - 8e-11 41.4 0.6 2.2e-06 27.2 0.1 2.8 2 1 1 3 3 3 2 TPR repeat RPAP3_C PF13877.6 EGG22816.1 - 2.4e-09 37.6 0.0 8.2e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_8 PF13181.6 EGG22816.1 - 5.6e-09 35.5 1.5 0.094 13.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGG22816.1 - 5.9e-08 32.6 0.4 0.018 15.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG22816.1 - 6.1e-05 23.2 1.0 0.11 12.8 0.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG22816.1 - 9.3e-05 22.9 0.0 0.00022 21.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG22816.1 - 0.00054 20.1 0.0 0.086 13.0 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG22816.1 - 0.00088 19.9 0.0 2 9.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGG22816.1 - 0.00096 18.9 0.5 6.7 6.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG22816.1 - 0.001 19.0 0.6 0.019 14.9 0.0 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 EGG22816.1 - 0.024 14.7 0.3 0.064 13.3 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG22816.1 - 0.05 14.4 0.0 28 5.9 0.0 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG22816.1 - 0.067 13.4 1.5 0.17 12.1 1.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGG22816.1 - 0.19 12.4 1.2 35 5.3 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EGG22816.1 - 0.33 11.1 1.8 2 8.5 0.4 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain COG5 PF10392.9 EGG22816.1 - 2.2 8.4 9.0 0.33 11.1 0.3 2.6 2 0 0 2 2 2 0 Golgi transport complex subunit 5 TipE PF16972.5 EGG22816.1 - 2.5 7.2 13.6 2.1 7.4 8.3 2.2 2 0 0 2 2 2 0 Na+ channel auxiliary subunit TipE TRP PF06011.12 EGG22818.1 - 0.018 13.8 24.9 0.035 12.9 24.9 1.4 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel LRR_8 PF13855.6 EGG22819.1 - 3.5e-13 49.1 38.4 3.9e-05 23.3 3.4 6.6 5 1 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 EGG22819.1 - 2.6e-10 40.4 48.8 0.0039 17.6 5.5 9.0 6 3 2 8 8 8 6 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 EGG22819.1 - 0.082 13.2 2.5 0.19 12.0 2.5 1.7 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain CHB_HEX_C_1 PF13290.6 EGG22820.1 - 2.4e-05 24.2 20.3 0.0012 18.8 0.6 5.4 5 0 0 5 5 5 2 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 EGG22820.1 - 0.00021 21.3 9.8 0.087 13.0 0.5 4.5 4 0 0 4 4 4 2 Fn3 associated Oest_recep PF02159.15 EGG22820.1 - 0.026 15.0 0.6 0.16 12.5 0.6 2.5 1 0 0 1 1 1 0 Oestrogen receptor APC_15aa PF05972.11 EGG22820.1 - 0.18 12.1 1.1 0.79 10.1 0.1 2.7 2 0 0 2 2 2 0 APC 15 residue motif Ank_2 PF12796.7 EGG22821.1 - 1.7e-26 92.6 15.9 4.8e-06 27.1 0.0 7.3 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22821.1 - 9.1e-25 86.4 15.5 0.00089 19.5 0.0 11.6 4 2 9 13 13 13 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG22821.1 - 9.4e-25 86.7 10.0 1.8e-05 25.1 0.0 8.1 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22821.1 - 1.1e-12 46.9 3.2 4.1 8.3 0.0 12.1 14 0 0 14 14 14 2 Ankyrin repeat DUF5049 PF16468.5 EGG22821.1 - 0.00011 22.0 1.3 33 4.5 0.0 6.9 5 3 3 8 8 8 0 Domain of unknown function (DUF5049) Ank PF00023.30 EGG22821.1 - 0.0051 17.2 3.6 79 4.0 0.2 7.4 5 3 0 5 5 5 0 Ankyrin repeat DUF4388 PF14332.6 EGG22821.1 - 0.045 14.0 0.0 22 5.4 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4388) YmaF PF12788.7 EGG22821.1 - 0.081 13.5 2.1 0.41 11.2 0.2 3.0 2 1 2 4 4 3 0 YmaF family ABC_membrane PF00664.23 EGG22822.1 - 5.8e-55 186.9 32.4 2.1e-27 96.5 9.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGG22822.1 - 2e-45 154.6 0.0 1.4e-25 90.4 0.0 3.1 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGG22822.1 - 5e-09 35.9 20.1 0.00027 20.5 2.1 4.7 3 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGG22822.1 - 0.00017 21.5 0.6 0.22 11.4 0.3 3.0 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGG22822.1 - 0.00032 20.4 1.5 0.4 10.5 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGG22822.1 - 0.0034 17.5 2.1 0.98 9.5 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase OATP PF03137.20 EGG22822.1 - 0.012 14.0 0.1 0.51 8.6 0.0 3.1 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family AAA_24 PF13479.6 EGG22822.1 - 0.02 14.6 4.1 0.064 13.0 0.0 3.3 3 1 0 3 3 3 0 AAA domain Pox_A32 PF04665.12 EGG22822.1 - 0.3 10.5 5.9 1.8 8.0 0.0 3.5 3 0 0 3 3 3 0 Poxvirus A32 protein RNA_pol_Rpc4 PF05132.14 EGG22822.1 - 0.34 11.3 0.0 0.34 11.3 0.0 3.6 4 0 0 4 4 4 0 RNA polymerase III RPC4 Med2 PF11214.8 EGG22823.1 - 0.12 12.5 1.2 0.31 11.2 1.2 1.6 1 1 0 1 1 1 0 Mediator complex subunit 2 Ras PF00071.22 EGG22824.1 - 4.9e-08 32.7 0.0 1.5e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Ras family Ank_2 PF12796.7 EGG22824.1 - 2.3e-05 24.9 0.1 0.00017 22.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Nucleoporin_FG PF13634.6 EGG22824.1 - 0.0025 18.6 7.3 0.0061 17.4 7.3 1.6 1 0 0 1 1 1 1 Nucleoporin FG repeat region Ank_4 PF13637.6 EGG22824.1 - 0.0046 17.5 0.6 0.1 13.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22824.1 - 0.023 15.0 0.0 0.17 12.2 0.0 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22824.1 - 0.024 15.1 0.2 4.9 8.1 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeat Dickkopf_N PF04706.12 EGG22825.1 - 0.00084 19.8 13.8 0.00084 19.8 13.8 5.5 4 2 1 5 5 5 2 Dickkopf N-terminal cysteine-rich region Ras PF00071.22 EGG22826.1 - 9.1e-09 35.1 0.1 2.4e-08 33.7 0.1 1.7 1 1 0 1 1 1 1 Ras family Ank_2 PF12796.7 EGG22826.1 - 3.1e-06 27.7 0.4 0.0047 17.5 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Phe_ZIP PF08916.11 EGG22826.1 - 0.26 12.0 1.2 0.38 11.5 0.1 1.9 2 0 0 2 2 2 0 Phenylalanine zipper MIP-T3 PF10243.9 EGG22828.1 - 0.095 12.7 2.2 5.3 7.1 0.0 3.2 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 CH-like domain Ank_2 PF12796.7 EGG22828.1 - 0.34 11.5 4.1 88 3.8 0.0 4.6 5 0 0 5 5 5 0 Ankyrin repeats (3 copies) IML1 PF12257.8 EGG22830.1 - 4.4e-114 380.4 1.2 4.4e-114 380.4 1.2 2.1 2 0 0 2 2 2 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EGG22830.1 - 2.7e-14 53.0 0.4 3.2e-08 33.5 0.0 3.0 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Hydrolase_4 PF12146.8 EGG22830.1 - 0.17 11.1 0.1 0.35 10.1 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Dickkopf_N PF04706.12 EGG22831.1 - 0.014 15.9 11.3 0.014 15.9 11.3 6.1 3 1 2 5 5 5 0 Dickkopf N-terminal cysteine-rich region ETRAMP PF09716.10 EGG22831.1 - 1.4 9.0 0.0 1.4 9.0 0.0 2.7 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) GET2 PF08690.10 EGG22831.1 - 1.8 8.1 6.4 2.9 7.5 6.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 fn3 PF00041.21 EGG22832.1 - 2.1e-07 31.2 11.3 0.25 11.7 0.2 6.1 6 0 0 6 6 6 3 Fibronectin type III domain CD99L2 PF12301.8 EGG22832.1 - 0.11 12.8 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 CD99 antigen like protein 2 IL3Ra_N PF18611.1 EGG22832.1 - 2.4 8.2 5.9 1.4 9.0 0.0 3.6 4 0 0 4 4 4 0 IL-3 receptor alpha chain N-terminal domain Arylsulfotran_N PF17425.2 EGG22832.1 - 3 7.9 17.4 0.34 11.0 0.2 4.9 5 0 0 5 5 5 0 Arylsulfotransferase Ig-like domain GYF PF02213.16 EGG22833.1 - 2.5e-10 39.9 0.1 9.1e-10 38.1 0.1 2.0 1 0 0 1 1 1 1 GYF domain TraG_N PF07916.11 EGG22833.1 - 0.42 9.4 2.0 0.69 8.7 2.0 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Ubiq_cyt_C_chap PF03981.12 EGG22834.1 - 3.6e-32 111.4 0.2 7.2e-32 110.4 0.2 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Macoilin PF09726.9 EGG22834.1 - 0.017 13.7 0.9 0.02 13.5 0.9 1.1 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 EGG22834.1 - 2.3 7.8 11.1 3.4 7.2 11.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TIG PF01833.24 EGG22837.1 - 0.29 11.2 25.0 0.13 12.3 3.2 4.8 2 1 1 3 3 3 0 IPT/TIG domain ANAPC1 PF12859.7 EGG22838.1 - 8.5 7.0 10.5 30 5.2 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 TIG PF01833.24 EGG22839.1 - 1.3e-08 34.8 36.1 0.005 16.9 0.7 7.2 5 2 2 7 7 7 5 IPT/TIG domain VD10_N PF08476.10 EGG22839.1 - 1.7 8.3 7.0 14 5.4 0.2 3.9 4 0 0 4 4 4 0 Viral D10 N-terminal TIG PF01833.24 EGG22840.1 - 0.00019 21.4 100.9 0.013 15.5 4.0 13.4 7 3 5 12 12 12 9 IPT/TIG domain PAN_1 PF00024.26 EGG22840.1 - 0.98 9.4 14.6 4.8 7.2 0.0 5.9 7 0 0 7 7 7 0 PAN domain DUF681 PF05080.12 EGG22840.1 - 1.8 9.2 6.8 2.7 8.7 0.8 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF681) STN PF07660.14 EGG22840.1 - 2.3 8.1 5.8 13 5.7 0.2 4.6 4 0 0 4 4 4 0 Secretin and TonB N terminus short domain SR-25 PF10500.9 EGG22841.1 - 0.044 13.4 8.0 0.083 12.5 8.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 EGG22841.1 - 4.7 8.0 17.4 0.28 11.9 10.1 2.2 1 1 1 2 2 2 0 Immortalisation up-regulated protein Ras PF00071.22 EGG22842.1 - 1.6e-11 44.0 0.6 3.4e-10 39.8 0.6 2.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG22842.1 - 9.9e-06 25.8 0.3 0.00081 19.6 0.3 2.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EGG22842.1 - 0.064 13.0 0.3 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.9 EGG22842.1 - 0.093 11.3 8.7 0.14 10.7 8.7 1.2 1 0 0 1 1 1 0 Macoilin family EB PF01683.18 EGG22843.1 - 0.00066 19.9 4.9 0.0022 18.3 4.9 1.8 1 0 0 1 1 1 1 EB module EGF_2 PF07974.13 EGG22843.1 - 0.00068 20.0 16.0 0.0016 18.8 16.0 1.7 1 0 0 1 1 1 1 EGF-like domain DUF3844 PF12955.7 EGG22843.1 - 0.0012 19.0 1.1 0.0034 17.5 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) EGF_Tenascin PF18720.1 EGG22843.1 - 0.025 14.6 8.6 0.096 12.8 8.6 2.1 1 0 0 1 1 1 0 Tenascin EGF domain I-EGF_1 PF18372.1 EGG22843.1 - 0.24 11.5 8.4 0.66 10.1 8.4 1.8 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 EGG22843.1 - 0.97 9.8 13.8 0.56 10.6 10.9 2.2 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 EGG22843.1 - 5.4 7.8 19.0 0.059 14.0 10.5 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.13 EGG22844.1 - 0.00035 20.9 12.0 0.00088 19.6 12.0 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG22844.1 - 0.0022 18.0 5.0 0.0022 18.0 5.0 2.2 2 0 0 2 2 2 1 Tenascin EGF domain EB PF01683.18 EGG22844.1 - 0.0027 17.9 3.0 0.0065 16.7 3.0 1.6 1 0 0 1 1 1 1 EB module LRR_8 PF13855.6 EGG22844.1 - 0.0033 17.1 0.7 16 5.4 0.0 4.4 4 1 1 5 5 5 0 Leucine rich repeat DUF3844 PF12955.7 EGG22844.1 - 0.012 15.7 7.1 0.014 15.5 1.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3844) LRR19-TM PF15176.6 EGG22844.1 - 0.041 13.9 0.1 0.094 12.7 0.1 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Collectrin PF16959.5 EGG22844.1 - 0.082 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Renal amino acid transporter LRR_4 PF12799.7 EGG22844.1 - 0.11 13.0 4.6 12 6.5 0.2 5.1 5 1 1 6 6 5 0 Leucine Rich repeats (2 copies) Tox-PLDMTX PF15645.6 EGG22844.1 - 0.31 11.3 1.7 1.2 9.4 1.7 1.9 1 1 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold EGF PF00008.27 EGG22844.1 - 0.67 10.3 8.8 1.7 9.0 8.8 1.7 1 0 0 1 1 1 0 EGF-like domain EGF_CA PF07645.15 EGG22844.1 - 0.86 9.9 8.2 2.5 8.4 8.2 1.7 1 0 0 1 1 1 0 Calcium-binding EGF domain hEGF PF12661.7 EGG22844.1 - 2.5 8.9 8.6 6.4 7.6 8.6 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF Ank_2 PF12796.7 EGG22845.1 - 0.00016 22.2 4.2 9.3 6.9 0.0 6.1 7 2 0 7 7 7 2 Ankyrin repeats (3 copies) Branch PF02485.21 EGG22845.1 - 0.00071 19.2 9.9 0.006 16.1 0.6 2.4 2 0 0 2 2 2 2 Core-2/I-Branching enzyme Ank_3 PF13606.6 EGG22845.1 - 0.0016 18.7 1.6 40 5.2 0.0 5.9 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 EGG22845.1 - 0.0021 18.6 7.9 59 4.4 0.1 7.4 7 1 0 7 7 7 0 Ankyrin repeats (many copies) DUF3113 PF11310.8 EGG22845.1 - 0.013 15.4 1.0 12 5.9 0.1 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) Ank PF00023.30 EGG22845.1 - 0.59 10.7 4.3 20 5.9 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeat Cbl_N2 PF02761.14 EGG22845.1 - 1.6 9.5 7.6 20 6.0 0.4 3.9 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain Gas_vesicle PF00741.18 EGG22845.1 - 2.1 8.6 7.7 24 5.2 0.9 3.4 2 0 0 2 2 2 0 Gas vesicle protein tRNA_NucTran2_2 PF13735.6 EGG22846.1 - 0.16 12.0 0.4 0.36 10.8 0.4 1.6 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative DUF1289 PF06945.13 EGG22848.1 - 0.05 13.4 0.3 0.19 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Ank_2 PF12796.7 EGG22852.1 - 0.15 12.6 2.6 24 5.6 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeats (3 copies) F_actin_bind PF08919.10 EGG22856.1 - 0.0017 18.5 0.4 0.0066 16.5 0.1 2.2 2 0 0 2 2 2 1 F-actin binding Acyltransf_C PF16076.5 EGG22856.1 - 0.025 14.7 0.1 1.7 8.8 0.1 2.8 2 0 0 2 2 2 0 Acyltransferase C-terminus RhoGAP PF00620.27 EGG22859.1 - 5.8e-16 58.7 1.9 1.2e-15 57.7 0.4 2.4 2 0 0 2 2 2 1 RhoGAP domain NikR_C PF08753.11 EGG22859.1 - 3.1 8.0 5.4 11 6.2 0.1 4.0 2 1 1 3 3 3 0 NikR C terminal nickel binding domain SprA-related PF12118.8 EGG22860.1 - 0.006 15.8 17.5 0.006 15.8 17.5 2.3 2 0 0 2 2 2 1 SprA-related family RPA43_OB PF17875.1 EGG22860.1 - 0.27 11.9 5.8 0.79 10.4 5.8 1.7 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I TCP PF03634.13 EGG22860.1 - 0.93 10.0 15.7 0.28 11.7 9.0 2.6 2 0 0 2 2 2 0 TCP family transcription factor YABBY PF04690.13 EGG22860.1 - 1.8 9.1 9.0 1 9.9 3.2 2.5 2 0 0 2 2 2 0 YABBY protein Folate_carrier PF01770.18 EGG22860.1 - 2.1 7.0 6.4 3.9 6.1 6.4 1.3 1 0 0 1 1 1 0 Reduced folate carrier TERB2 PF15101.6 EGG22860.1 - 3.2 7.8 21.4 2.3 8.2 11.6 2.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Peptidase_S49_N PF08496.10 EGG22860.1 - 3.3 7.8 15.2 11 6.0 15.2 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CPSF100_C PF13299.6 EGG22860.1 - 3.7 7.7 11.3 0.78 9.9 4.0 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CLN3 PF02487.17 EGG22860.1 - 4.5 6.2 8.9 0.64 9.0 3.6 2.0 2 0 0 2 2 2 0 CLN3 protein CCSAP PF15748.5 EGG22860.1 - 4.5 7.4 19.3 0.47 10.6 10.6 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF4834 PF16118.5 EGG22860.1 - 6.1 7.9 16.1 1.3 10.0 8.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Macro PF01661.21 EGG22861.1 - 7.9e-29 100.1 0.1 2.4e-28 98.5 0.1 1.9 1 0 0 1 1 1 1 Macro domain PARP PF00644.20 EGG22861.1 - 1.4e-13 50.9 2.4 1.4e-13 50.9 2.4 3.2 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 EGG22861.1 - 3.6e-08 33.9 0.8 2.9e-07 31.0 0.8 2.8 1 0 0 1 1 1 1 WWE domain MADF_DNA_bdg PF10545.9 EGG22861.1 - 0.11 12.9 0.2 0.11 12.9 0.2 2.4 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SSrecog PF03531.14 EGG22861.1 - 0.54 10.2 4.1 1.5 8.8 0.1 3.5 4 0 0 4 4 4 0 Structure-specific recognition protein (SSRP1) Pkinase PF00069.25 EGG22862.1 - 3.7e-79 265.8 0.1 4.4e-79 265.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG22862.1 - 4.9e-37 127.6 0.0 6e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG22862.1 - 4.9e-11 42.5 0.0 4.6e-09 36.0 0.0 2.1 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 EGG22862.1 - 4.9e-05 23.4 0.0 0.02 14.8 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGG22862.1 - 0.0001 21.7 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGG22862.1 - 0.0003 19.7 0.3 0.002 17.0 0.0 1.8 1 1 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EGG22862.1 - 0.00034 20.3 0.8 0.054 13.1 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGG22862.1 - 0.0018 17.9 0.3 0.0029 17.2 0.3 1.2 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 EGG22862.1 - 0.11 11.9 0.3 0.2 11.2 0.3 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL PIP5K PF01504.18 EGG22863.1 - 9.5e-75 251.3 0.6 9.5e-75 251.3 0.6 3.7 4 0 0 4 4 4 1 Phosphatidylinositol-4-phosphate 5-Kinase C1_1 PF00130.22 EGG22863.1 - 5.7e-13 48.5 3.2 1.1e-12 47.6 3.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_4 PF13637.6 EGG22863.1 - 6.8e-13 48.9 0.0 1.2e-06 28.9 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) EF-hand_7 PF13499.6 EGG22863.1 - 9.8e-13 48.4 3.8 3.9e-06 27.2 0.5 3.9 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 EGG22863.1 - 1.4e-12 46.2 1.7 0.0029 17.0 0.2 4.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGG22863.1 - 1.5e-12 46.4 1.2 0.0089 15.9 0.3 4.4 3 0 0 3 3 3 3 EF-hand domain Ank_2 PF12796.7 EGG22863.1 - 1.5e-12 47.9 0.0 3.4e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG22863.1 - 5.9e-11 42.4 0.0 2.5e-06 27.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG22863.1 - 1.5e-09 37.3 0.0 0.00012 22.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EGG22863.1 - 2e-09 37.4 0.0 6.6e-07 29.5 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat EF-hand_8 PF13833.6 EGG22863.1 - 5.2e-05 23.0 1.7 0.081 12.8 0.3 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG22863.1 - 0.00036 19.9 0.1 0.14 11.7 0.3 2.9 2 0 0 2 2 2 1 EF hand NADPH_Ox PF08414.10 EGG22863.1 - 0.0029 17.9 0.1 0.011 16.0 0.1 2.0 1 0 0 1 1 1 1 Respiratory burst NADPH oxidase C1_2 PF03107.16 EGG22863.1 - 0.025 14.9 4.2 0.063 13.6 4.2 1.8 1 0 0 1 1 1 0 C1 domain MMR_HSR1 PF01926.23 EGG22864.1 - 2.1e-14 53.6 0.0 1.6e-12 47.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG22864.1 - 5e-06 26.1 0.1 0.00066 19.2 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGG22864.1 - 5e-05 23.3 0.1 0.0028 17.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase NOA36 PF06524.12 EGG22864.1 - 0.0014 18.0 20.9 0.0014 18.0 20.9 2.4 2 0 0 2 2 2 1 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EGG22864.1 - 0.01 16.1 20.9 0.01 16.1 20.9 3.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Dynamin_N PF00350.23 EGG22864.1 - 0.048 13.7 0.5 0.048 13.7 0.5 3.8 4 1 1 5 5 5 0 Dynamin family Roc PF08477.13 EGG22864.1 - 0.14 12.3 2.3 1.3 9.3 0.2 3.0 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Sigma70_ner PF04546.13 EGG22864.1 - 1.3 8.9 23.6 0.035 14.0 14.6 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region CUE PF02845.16 EGG22865.1 - 0.0002 21.0 0.3 0.00048 19.8 0.3 1.7 1 0 0 1 1 1 1 CUE domain FlxA PF14282.6 EGG22865.1 - 0.00083 19.3 7.2 0.00083 19.3 7.2 4.7 4 1 0 4 4 4 2 FlxA-like protein DUF572 PF04502.13 EGG22867.1 - 1.5 8.3 22.2 2.4 7.7 22.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) LAP1C PF05609.12 EGG22867.1 - 2 7.4 18.6 3 6.8 18.6 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 EGG22867.1 - 2.8 5.0 14.7 3.3 4.7 14.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hydin_ADK PF17213.3 EGG22867.1 - 5.9 7.1 13.4 21 5.3 9.1 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain EF-hand_1 PF00036.32 EGG22868.1 - 1.1e-20 71.5 2.8 1.3e-06 27.6 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGG22868.1 - 1.1e-19 70.6 0.2 1.7e-11 44.4 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGG22868.1 - 3.5e-18 63.9 2.1 4.9e-07 29.2 0.7 3.8 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGG22868.1 - 1.1e-13 50.8 4.4 0.00032 20.5 0.1 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGG22868.1 - 1.8e-13 49.3 1.6 6.4e-05 22.3 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EGG22868.1 - 1.2e-06 28.7 0.0 0.00035 20.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EGG22868.1 - 0.00095 19.5 0.6 0.37 11.1 0.0 2.3 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF2666 PF10869.8 EGG22868.1 - 0.0016 18.7 0.4 1.2 9.4 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2666) DUF3349 PF11829.8 EGG22868.1 - 0.0026 18.5 0.2 5.2 7.9 0.1 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3349) Caleosin PF05042.13 EGG22868.1 - 0.0031 17.4 0.0 0.0068 16.4 0.0 1.7 1 1 0 1 1 1 1 Caleosin related protein Toprim_2 PF13155.6 EGG22868.1 - 0.0068 16.8 0.5 0.32 11.4 0.0 2.2 1 1 1 2 2 2 1 Toprim-like EF-hand_4 PF12763.7 EGG22868.1 - 0.01 15.7 0.2 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF4497 PF14924.6 EGG22868.1 - 0.018 15.5 0.1 0.69 10.4 0.0 2.3 2 1 0 3 3 2 0 Protein of unknown function (DUF4497) Sec34 PF04136.15 EGG22868.1 - 0.079 12.8 2.7 5.4 6.9 0.1 2.9 1 1 2 3 3 3 0 Sec34-like family Ilar_coat PF01787.16 EGG22868.1 - 0.08 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Ilarvirus coat protein GhoS PF11080.8 EGG22868.1 - 0.11 12.4 0.4 16 5.5 0.0 2.2 1 1 1 2 2 2 0 Endoribonuclease GhoS RRM_1 PF00076.22 EGG22869.1 - 3.9e-05 23.4 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BNIP2 PF12496.8 EGG22869.1 - 1.4 9.3 8.7 2.2 8.7 8.1 1.7 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DIL PF01843.19 EGG22870.1 - 5.2e-21 74.9 2.7 7.5e-21 74.4 0.0 2.8 3 0 0 3 3 3 1 DIL domain NT-C2 PF10358.9 EGG22870.1 - 7.4e-21 74.4 2.8 2.1e-20 73.0 2.8 1.8 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SlyX PF04102.12 EGG22870.1 - 6.5e-06 26.7 38.6 3e-05 24.5 0.4 8.0 6 3 1 7 7 7 2 SlyX Filament PF00038.21 EGG22870.1 - 0.00047 19.8 50.9 0.0012 18.5 27.9 4.3 2 1 2 4 4 4 3 Intermediate filament protein MAD PF05557.13 EGG22870.1 - 0.001 17.6 2.5 0.001 17.6 2.5 4.4 3 1 0 3 3 3 2 Mitotic checkpoint protein HMMR_N PF15905.5 EGG22870.1 - 0.0044 16.5 18.9 0.0044 16.5 18.9 5.0 2 2 0 3 3 3 1 Hyaluronan mediated motility receptor N-terminal Cnn_1N PF07989.11 EGG22870.1 - 0.015 15.5 0.4 0.015 15.5 0.4 8.7 5 3 1 7 7 7 0 Centrosomin N-terminal motif 1 DUF3138 PF11336.8 EGG22870.1 - 1.9 7.0 8.8 6.3 5.3 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3138) START PF01852.19 EGG22871.1 - 0.00011 21.7 0.0 0.0002 20.9 0.0 1.6 1 1 0 1 1 1 1 START domain Abhydrolase_1 PF00561.20 EGG22872.1 - 1.9e-06 27.7 0.5 5.5e-06 26.2 0.2 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG22872.1 - 0.00048 20.8 0.0 0.00075 20.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family KH_1 PF00013.29 EGG22873.1 - 0.00037 20.2 0.4 0.0012 18.6 0.4 1.9 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 EGG22873.1 - 0.0022 18.0 0.6 0.0055 16.8 0.1 1.9 2 0 0 2 2 2 1 Krr1 KH1 domain NinB PF05772.12 EGG22873.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 NinB protein Amino_oxidase PF01593.24 EGG22874.1 - 6.5e-66 223.5 0.0 1e-65 222.8 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGG22874.1 - 8.5e-15 54.7 0.1 1.8e-14 53.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG22874.1 - 1.9e-09 37.6 0.0 6.8e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGG22874.1 - 6e-07 29.9 0.2 5.9e-05 23.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGG22874.1 - 1.1e-06 28.2 0.0 5.8e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGG22874.1 - 2.1e-06 27.1 0.4 4.1e-06 26.1 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGG22874.1 - 5.5e-06 25.8 0.0 1.9e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGG22874.1 - 7.7e-06 25.2 0.0 0.0047 16.0 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 EGG22874.1 - 3.7e-05 23.0 0.0 5.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGG22874.1 - 4.3e-05 22.4 0.1 6.9e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 EGG22874.1 - 0.00046 19.6 0.1 0.00084 18.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GDI PF00996.18 EGG22874.1 - 0.00079 18.1 0.0 0.0015 17.1 0.0 1.4 1 0 0 1 1 1 1 GDP dissociation inhibitor Thi4 PF01946.17 EGG22874.1 - 0.0014 18.0 0.2 0.0052 16.1 0.2 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 EGG22874.1 - 0.077 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGG22874.1 - 0.16 11.9 0.4 23 5.0 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EGG22874.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain BspA_v PF18220.1 EGG22878.1 - 0.0069 16.5 0.5 0.0081 16.3 0.5 1.1 1 0 0 1 1 1 1 Adhesin BspA variable domain EFG_IV PF03764.18 EGG22879.1 - 6.2e-27 93.8 0.0 2.5e-26 91.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EGG22879.1 - 6.1e-21 74.3 0.0 2.3e-20 72.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGG22879.1 - 1.4e-13 51.0 0.0 3.4e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGG22879.1 - 1.8e-11 44.0 0.0 3.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 EGG22879.1 - 0.00068 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain HEAT PF02985.22 EGG22883.1 - 1.9e-05 24.5 1.5 0.17 12.2 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EGG22883.1 - 6.6e-05 23.4 1.4 0.0024 18.4 0.2 3.4 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGG22883.1 - 8e-05 22.7 6.2 0.025 14.6 0.4 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGG22883.1 - 0.011 16.1 0.0 2.4 8.6 0.0 3.1 1 1 2 3 3 3 0 HEAT repeats HEAT_2 PF13646.6 EGG22884.1 - 0.058 13.8 0.0 1.4 9.4 0.0 2.6 3 0 0 3 3 3 0 HEAT repeats EFG_C PF00679.24 EGG22885.1 - 1.6e-20 72.9 0.0 3.2e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 EGG22885.1 - 9.6e-08 31.8 0.3 2.4e-05 24.1 0.0 2.2 1 1 1 2 2 2 2 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 EGG22886.1 - 2.2e-13 50.4 0.3 4.6e-13 49.4 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 2OG-FeII_Oxy_3 PF13640.6 EGG22887.1 - 9.6e-10 39.2 0.0 2.2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GTP_CH_N PF12471.8 EGG22887.1 - 0.014 15.2 0.1 0.037 13.8 0.1 1.7 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal SDA1 PF05285.12 EGG22887.1 - 0.1 12.0 8.0 0.2 11.0 8.0 1.4 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 EGG22887.1 - 1.7 7.3 12.5 0.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Presenilin NOA36 PF06524.12 EGG22887.1 - 4.4 6.5 7.3 11 5.3 7.3 1.6 1 0 0 1 1 1 0 NOA36 protein Lipase_3 PF01764.25 EGG22888.1 - 2.3e-25 89.1 0.0 3.5e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) CBM49 PF09478.10 EGG22888.1 - 6.9e-06 26.3 0.5 8.7e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 DUF2974 PF11187.8 EGG22888.1 - 0.011 15.3 0.4 0.068 12.7 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EGG22888.1 - 0.1 13.2 0.1 0.23 12.0 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family 2OG-FeII_Oxy_3 PF13640.6 EGG22890.1 - 4.2e-10 40.4 0.0 1e-09 39.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGG22890.1 - 0.0039 17.6 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAM176 PF14851.6 EGG22890.1 - 4 7.1 8.6 11 5.7 8.6 1.7 1 0 0 1 1 1 0 FAM176 family Dicty_REP PF05086.12 EGG22890.1 - 4.5 5.1 10.7 6.8 4.5 10.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein EGF_2 PF07974.13 EGG22891.1 - 0.011 16.1 12.8 0.024 15.0 12.8 1.6 1 0 0 1 1 1 0 EGF-like domain fn3 PF00041.21 EGG22891.1 - 0.029 14.7 0.0 0.079 13.3 0.0 1.8 1 0 0 1 1 1 0 Fibronectin type III domain S_locus_glycop PF00954.20 EGG22891.1 - 0.035 14.6 0.3 0.11 13.1 0.3 1.9 1 0 0 1 1 1 0 S-locus glycoprotein domain Laminin_EGF PF00053.24 EGG22891.1 - 0.054 13.7 4.6 0.13 12.4 4.6 1.6 1 0 0 1 1 1 0 Laminin EGF domain EGF PF00008.27 EGG22891.1 - 0.93 9.9 9.4 2.5 8.5 9.4 1.8 1 0 0 1 1 1 0 EGF-like domain 2OG-FeII_Oxy_3 PF13640.6 EGG22892.1 - 1.1e-07 32.6 0.0 2.6e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NOA36 PF06524.12 EGG22892.1 - 0.0074 15.7 16.5 0.017 14.5 16.5 1.6 1 0 0 1 1 1 1 NOA36 protein BUD22 PF09073.10 EGG22892.1 - 0.41 9.9 9.8 0.65 9.3 9.8 1.2 1 0 0 1 1 1 0 BUD22 TFB6 PF17110.5 EGG22892.1 - 0.87 9.3 6.3 2 8.1 6.3 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SpoIIIAH PF12685.7 EGG22892.1 - 1.4 8.7 12.1 0.035 13.9 5.2 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein RPN2_C PF18004.1 EGG22892.1 - 1.6 8.6 6.6 4.2 7.3 6.6 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SDA1 PF05285.12 EGG22892.1 - 2.5 7.4 16.0 3.9 6.8 16.0 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGG22892.1 - 2.8 6.0 17.5 6.2 4.9 17.5 1.5 1 0 0 1 1 1 0 Nop14-like family DUF1748 PF08520.10 EGG22893.1 - 1.3e-09 37.8 0.1 1.9e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Sugarporin_N PF11471.8 EGG22896.1 - 0.086 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension MRPL52 PF18699.1 EGG22897.1 - 6.7e-26 90.3 0.4 8.6e-26 90.0 0.4 1.1 1 0 0 1 1 1 1 Mitoribosomal protein mL52 HSBP1 PF06825.12 EGG22897.1 - 0.021 14.6 4.1 0.08 12.8 3.6 1.9 1 1 0 1 1 1 0 Heat shock factor binding protein 1 FUSC_2 PF13515.6 EGG22898.1 - 8.2e-13 48.6 14.1 1.5e-12 47.7 14.1 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 EGG22898.1 - 0.033 12.7 2.9 0.05 12.1 2.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fz PF01392.22 EGG22903.1 - 0.013 16.1 3.5 0.026 15.2 3.5 1.4 1 0 0 1 1 1 0 Fz domain LINES_N PF14694.6 EGG22904.1 - 1.1e-12 48.1 6.8 1.1e-12 48.1 6.8 2.1 2 1 0 2 2 2 1 Lines N-terminus LINES_C PF14695.6 EGG22904.1 - 4.8e-05 22.7 0.4 0.00014 21.2 0.4 1.8 1 0 0 1 1 1 1 Lines C-terminus Asp PF00026.23 EGG22905.1 - 8.5e-36 124.0 0.9 1.9e-35 122.8 0.9 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGG22905.1 - 3e-13 49.9 0.0 7.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 EGG22905.1 - 1.2e-10 41.9 3.6 1.2e-10 41.9 3.6 2.5 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal SUIM_assoc PF16619.5 EGG22905.1 - 0.79 9.8 10.4 0.3 11.2 4.5 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Snf7 PF03357.21 EGG22906.1 - 1.5e-30 106.1 24.2 2.1e-30 105.6 24.2 1.2 1 0 0 1 1 1 1 Snf7 PIEZO PF15917.5 EGG22906.1 - 0.11 11.9 13.3 0.016 14.7 9.2 1.5 1 1 1 2 2 2 0 Piezo Mnd1 PF03962.15 EGG22906.1 - 0.46 10.8 2.9 0.41 11.0 0.4 2.1 2 0 0 2 2 2 0 Mnd1 HTH domain YlqD PF11068.8 EGG22906.1 - 2.1 8.7 19.8 0.31 11.4 12.1 2.1 1 1 1 2 2 2 0 YlqD protein PP2C PF00481.21 EGG22907.1 - 2.4e-31 109.3 0.6 2.4e-31 109.3 0.6 2.4 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGG22907.1 - 2.4e-09 37.2 0.0 4.3e-06 26.5 0.0 2.8 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EGG22907.1 - 1.8e-06 28.0 0.0 0.019 14.9 0.0 2.5 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) zf-CDGSH PF09360.10 EGG22910.1 - 0.0022 18.2 0.3 0.0022 18.2 0.3 3.0 2 1 0 2 2 2 1 Iron-binding zinc finger CDGSH type VIT1 PF01988.19 EGG22911.1 - 5.4e-26 91.8 0.0 1.4e-25 90.4 0.0 1.7 1 1 0 1 1 1 1 VIT family DUF5305 PF17231.2 EGG22911.1 - 0.068 12.6 0.3 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Sec23_helical PF04815.15 EGG22911.1 - 0.21 11.4 0.1 0.39 10.6 0.1 1.3 1 0 0 1 1 1 0 Sec23/Sec24 helical domain Nop52 PF05997.12 EGG22912.1 - 0.011 15.5 0.5 0.021 14.6 0.0 1.6 2 0 0 2 2 2 0 Nucleolar protein,Nop52 Kinesin PF00225.23 EGG22913.1 - 2e-44 151.9 0.0 2e-44 151.9 0.0 3.7 4 1 0 4 4 4 1 Kinesin motor domain WD40 PF00400.32 EGG22913.1 - 1.9e-19 69.6 26.8 9.9e-05 23.0 0.5 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Pept_S41_N PF18294.1 EGG22914.1 - 0.07 13.1 0.4 0.2 11.7 0.4 1.7 1 0 0 1 1 1 0 Peptidase S41 N-terminal domain LRR_6 PF13516.6 EGG22914.1 - 1.7 8.9 6.9 9.1 6.6 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat 2-Hacid_dh PF00389.30 EGG22915.1 - 0.012 15.3 0.0 6.8 6.4 0.0 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain LRR_8 PF13855.6 EGG22916.1 - 0.18 11.6 3.8 24 4.8 0.0 4.3 4 1 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 EGG22916.1 - 0.2 11.8 1.7 11 6.4 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 EGG22917.1 - 0.027 14.2 8.4 0.4 10.5 0.2 4.6 3 2 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 EGG22917.1 - 0.12 12.5 4.8 8.2 6.8 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat Fib_alpha PF08702.10 EGG22917.1 - 0.29 11.3 1.2 1.7 8.8 0.2 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TPR_2 PF07719.17 EGG22918.1 - 3.8e-14 51.6 7.3 2.8e-06 27.0 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG22918.1 - 1.2e-13 50.3 8.5 1.4e-06 27.8 1.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG22918.1 - 4.4e-09 35.9 8.2 0.00028 20.5 0.6 2.9 2 0 0 2 2 2 2 TPR repeat SET PF00856.28 EGG22918.1 - 2.1e-07 31.5 0.0 1.1e-06 29.2 0.0 2.2 1 1 0 1 1 1 1 SET domain TPR_16 PF13432.6 EGG22918.1 - 3.9e-07 30.6 1.8 0.0067 17.1 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG22918.1 - 4.9e-07 29.3 1.3 0.00086 19.2 0.5 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG22918.1 - 1.3e-06 28.7 0.3 0.0087 16.8 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG22918.1 - 2e-06 27.6 9.6 3.3e-05 23.7 1.3 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG22918.1 - 3.3e-06 27.4 2.9 0.0004 20.8 1.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 EGG22918.1 - 5.6e-06 26.2 3.1 0.00063 19.7 0.7 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG22918.1 - 5.4e-05 23.2 3.4 0.03 14.4 0.8 3.2 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 EGG22918.1 - 0.00016 21.9 8.0 0.038 14.3 0.1 3.3 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG22918.1 - 0.0019 18.7 6.0 0.19 12.2 0.7 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG22918.1 - 0.0025 18.0 7.6 0.16 12.2 0.5 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 RuvB_C PF05491.13 EGG22918.1 - 0.017 15.0 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain TPR_9 PF13371.6 EGG22918.1 - 0.018 15.2 0.1 4.3 7.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGG22918.1 - 0.067 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat BTAD PF03704.17 EGG22918.1 - 0.17 12.3 0.2 0.34 11.4 0.2 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain MIT PF04212.18 EGG22918.1 - 0.2 11.7 6.9 2.9 8.0 0.8 3.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EGG22918.1 - 2.5 8.1 5.8 6.2 6.8 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RhoGEF PF00621.20 EGG22919.1 - 1e-38 133.4 1.1 1e-38 133.4 1.1 3.6 3 0 0 3 3 3 1 RhoGEF domain IQ PF00612.27 EGG22919.1 - 0.0001 21.8 0.2 0.0001 21.8 0.2 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif IQ_SEC7_PH PF16453.5 EGG22919.1 - 0.016 15.2 0.9 0.016 15.2 0.9 3.4 3 1 0 3 3 3 0 PH domain zf-C2H2_9 PF16293.5 EGG22919.1 - 0.16 11.8 0.4 0.49 10.3 0.4 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 EGG22919.1 - 0.25 11.2 4.5 0.32 10.9 0.0 3.1 2 0 0 2 2 2 0 Rad50 zinc hook motif F-box-like PF12937.7 EGG22921.1 - 0.00075 19.3 0.7 0.0084 16.0 0.5 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EGG22921.1 - 2.6 8.6 14.1 0.32 11.5 0.4 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) PRKCSH_1 PF13015.6 EGG22922.1 - 4.4e-07 29.7 0.0 5.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein CIMR PF00878.18 EGG22922.1 - 0.0023 18.0 0.2 0.078 13.0 0.1 2.0 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 EGG22922.1 - 0.0067 16.3 0.0 0.0071 16.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 EGG22922.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Beach PF02138.18 EGG22923.1 - 1.5e-23 83.6 2.6 6.2e-23 81.6 0.2 2.8 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 EGG22923.1 - 1.6e-14 53.8 0.0 1e-13 51.2 0.0 2.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EGG22923.1 - 1.2e-09 38.6 15.4 0.0057 17.5 0.1 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF4800 PF16057.5 EGG22923.1 - 0.0001 21.7 5.2 0.00034 20.0 5.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) EB PF01683.18 EGG22925.1 - 0.0017 18.6 18.5 0.0029 17.9 8.9 7.9 4 4 3 7 7 7 5 EB module PH PF00169.29 EGG22927.1 - 0.00012 22.5 0.0 0.00029 21.3 0.0 1.6 1 0 0 1 1 1 1 PH domain PspC PF04024.12 EGG22927.1 - 0.94 9.3 7.2 4.5 7.2 0.1 2.5 2 0 0 2 2 2 0 PspC domain ECF_trnsprt PF12822.7 EGG22927.1 - 2 8.5 8.7 2.3e+02 1.8 9.2 2.1 1 1 0 1 1 1 0 ECF transporter, substrate-specific component EB PF01683.18 EGG22928.1 - 0.004 17.4 19.9 0.0096 16.2 3.9 12.5 5 3 5 11 11 11 6 EB module Neogenin_C PF06583.12 EGG22928.1 - 0.0044 16.9 0.1 0.0096 15.8 0.1 1.5 1 0 0 1 1 1 1 Neogenin C-terminus FNIP PF05725.12 EGG22929.1 - 3.9e-10 39.7 5.3 3.2e-05 24.0 0.3 10.6 9 2 2 11 11 11 5 FNIP Repeat DUF3598 PF12204.8 EGG22929.1 - 0.0073 15.8 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3598) RICTOR_phospho PF14665.6 EGG22930.1 - 0.00034 20.9 0.9 0.0024 18.2 0.1 2.2 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, phosphorylation-site OrfB_Zn_ribbon PF07282.11 EGG22932.1 - 3.5e-06 26.8 0.0 0.0024 17.8 0.0 3.2 2 0 0 2 2 2 2 Putative transposase DNA-binding domain DUF2992 PF11208.8 EGG22932.1 - 0.76 10.0 0.0 0.76 10.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) EB PF01683.18 EGG22933.1 - 0.0033 17.7 3.8 0.0033 17.7 3.8 7.3 3 2 4 7 7 7 4 EB module EAV_GP5 PF15981.5 EGG22933.1 - 9.1 6.8 17.4 0.75 10.2 0.6 3.5 3 0 0 3 3 3 0 Envelope glycoprotein GP 5 of equine arteritis virus GARS_A PF01071.19 EGG22934.1 - 2.2e-59 200.5 0.1 6.2e-59 199.1 0.1 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 EGG22934.1 - 1.6e-31 109.6 0.0 4.7e-31 108.0 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 EGG22934.1 - 2.5e-31 108.3 0.2 1.6e-30 105.7 0.1 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EGG22934.1 - 1.6e-18 66.7 0.1 5.1e-18 65.1 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EGG22934.1 - 1.5e-14 54.4 0.7 4.4e-14 52.9 0.7 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 EGG22934.1 - 1.3e-05 24.8 0.1 2.6e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EGG22934.1 - 4.8e-05 23.0 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGG22934.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EGG22934.1 - 0.0019 17.8 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EGG22934.1 - 0.0033 17.0 0.0 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 EGG22934.1 - 0.043 13.1 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp adh_short PF00106.25 EGG22935.1 - 1.2e-48 165.2 0.0 1.4e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG22935.1 - 5.8e-42 143.8 0.0 6.9e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG22935.1 - 8.6e-14 51.8 0.0 1.2e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG22935.1 - 2.2e-05 24.0 0.0 0.00012 21.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGG22935.1 - 0.058 12.5 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_transf_17 PF04724.13 EGG22938.1 - 7.3e-18 64.7 0.5 1.7e-17 63.5 0.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 17 Glyco_transf_8 PF01501.20 EGG22939.1 - 2.1e-06 27.5 11.6 1e-05 25.3 2.0 2.9 2 1 1 3 3 3 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGG22939.1 - 0.0088 15.4 0.2 0.0088 15.4 0.2 2.0 2 0 0 2 2 2 1 Mannosyltransferase putative TFIIF_beta PF02270.15 EGG22940.1 - 6.8e-23 80.6 0.7 1.2e-22 79.8 0.7 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 EGG22940.1 - 2.4e-09 38.0 0.2 5.2e-09 36.9 0.2 1.7 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 EGG22940.1 - 1.4e-05 26.0 0.2 2.1e-05 25.3 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DDE_Tnp_IS66_C PF13817.6 EGG22940.1 - 0.071 13.3 0.1 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 IS66 C-terminal element DUF3439 PF11921.8 EGG22941.1 - 5.9 6.9 15.7 12 5.9 15.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Hira PF07569.11 EGG22943.1 - 7.4e-46 156.7 2.3 7.4e-46 156.7 2.3 2.7 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 EGG22943.1 - 2.1e-30 104.3 21.7 5.3e-07 30.2 0.2 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG22943.1 - 5e-10 39.5 0.4 0.49 10.7 0.0 6.2 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGG22943.1 - 0.0082 16.1 1.0 3 7.9 0.2 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EGG22943.1 - 0.056 12.8 0.4 52 3.0 0.0 4.5 4 2 2 6 6 6 0 WD40-like domain HIRA_B PF09453.10 EGG22943.1 - 0.065 13.1 1.7 0.22 11.4 1.7 1.9 1 0 0 1 1 1 0 HIRA B motif DUF4776 PF16003.5 EGG22943.1 - 5.4 5.9 27.0 10 5.0 27.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Porin_3 PF01459.22 EGG22944.1 - 9e-12 45.0 0.0 2.5e-11 43.6 0.0 1.6 1 1 1 2 2 2 1 Eukaryotic porin MDM10 PF12519.8 EGG22944.1 - 5.2e-09 35.5 0.5 3.1e-08 32.9 0.5 1.9 1 1 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 PGM_PMM_I PF02878.16 EGG22945.1 - 7.5e-36 122.9 0.1 1.5e-35 121.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EGG22945.1 - 8.3e-26 90.4 0.0 1.8e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGG22945.1 - 1.7e-13 51.1 0.0 4.3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EGG22945.1 - 6.7e-06 26.2 0.0 1.9e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1882 PF08966.11 EGG22945.1 - 0.011 16.0 0.8 2.8 8.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) AICARFT_IMPCHas PF01808.18 EGG22950.1 - 3.8e-106 354.9 0.0 5.2e-106 354.4 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EGG22950.1 - 5.3e-24 84.2 0.0 1.3e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain LpxI_C PF06230.11 EGG22950.1 - 0.071 13.0 0.1 2.3 8.0 0.1 3.1 3 0 0 3 3 3 0 LpxI C-terminal domain ASD2 PF08687.11 EGG22951.1 - 0.035 13.7 10.3 0.042 13.4 10.3 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Zip PF02535.22 EGG22951.1 - 1 8.5 9.0 1.3 8.2 9.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGG22951.1 - 1.2 7.8 19.7 1.5 7.5 19.7 1.0 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 EGG22951.1 - 2.8 7.9 14.3 3.5 7.6 14.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.16 EGG22951.1 - 4 7.4 10.4 4.9 7.1 10.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Voltage_CLC PF00654.20 EGG22952.1 - 2.1e-48 165.4 5.5 2.1e-48 165.4 5.5 1.7 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGG22952.1 - 0.0098 16.3 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 1 CBS domain Pex14_N PF04695.13 EGG22952.1 - 0.11 13.1 4.6 0.54 10.9 1.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 EGG22952.1 - 1.7 8.5 8.0 0.14 12.1 3.4 1.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) WD40 PF00400.32 EGG22953.1 - 0.001 19.8 6.8 16 6.5 0.0 5.6 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG22953.1 - 0.0027 18.0 0.0 0.23 11.8 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Patatin PF01734.22 EGG22955.1 - 2e-16 60.8 0.0 3.4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase DUF2119 PF09892.9 EGG22956.1 - 0.0044 16.4 0.3 0.0087 15.5 0.2 1.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2119) DUF3088 PF11287.8 EGG22956.1 - 0.042 13.6 0.1 0.074 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) Suf PF05843.14 EGG22956.1 - 0.047 13.7 0.4 0.071 13.1 0.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3456 PF11938.8 EGG22956.1 - 0.1 13.1 0.3 0.22 12.0 0.3 1.4 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Pkinase PF00069.25 EGG22959.1 - 2.2e-72 243.6 0.2 4e-72 242.7 0.0 1.6 2 0 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG22959.1 - 7.1e-33 114.0 0.0 1.3e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG22959.1 - 2.1e-05 24.0 0.0 6.6e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGG22959.1 - 0.25 10.1 6.9 0.49 9.1 0.0 2.7 2 1 0 2 2 2 0 Fungal protein kinase Eapp_C PF10238.9 EGG22959.1 - 0.52 10.4 8.3 1.2 9.2 8.3 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF3915 PF13054.6 EGG22959.1 - 0.57 10.2 14.6 0.34 10.9 11.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) NARP1 PF12569.8 EGG22959.1 - 1.3 7.8 15.2 3.5 6.4 14.4 1.9 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 CDC45 PF02724.14 EGG22959.1 - 2 6.6 10.9 3 6.0 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 EGG22959.1 - 2.5 8.1 6.9 5.2 7.1 6.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAM176 PF14851.6 EGG22959.1 - 3.3 7.3 7.1 7.2 6.3 7.1 1.5 1 0 0 1 1 1 0 FAM176 family Zip PF02535.22 EGG22959.1 - 5.8 6.0 6.5 8.3 5.5 6.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter YL1 PF05764.13 EGG22959.1 - 6.6 6.8 27.8 0.65 10.1 19.1 2.3 2 0 0 2 2 2 0 YL1 nuclear protein PhoPQ_related PF10142.9 EGG22960.1 - 6.8e-104 347.4 0.8 8e-104 347.2 0.8 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Methyltransf_2 PF00891.18 EGG22961.1 - 7.4e-12 45.0 0.0 1.4e-06 27.7 0.0 2.1 1 1 1 2 2 2 2 O-methyltransferase domain Dimerisation2 PF16864.5 EGG22961.1 - 6.3e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain Peptidase_C54 PF03416.19 EGG22963.1 - 3.7e-90 302.1 0.0 5.4e-90 301.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Abhydrolase_1 PF00561.20 EGG22963.1 - 0.052 13.2 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold RL10P_insert PF17777.1 EGG22964.1 - 4.6e-20 71.4 0.5 9.3e-20 70.4 0.5 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EGG22964.1 - 1.1e-17 64.0 2.2 3e-17 62.6 2.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 EGG22964.1 - 6.3e-15 55.5 6.2 6.3e-15 55.5 6.2 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein PAH PF02671.21 EGG22964.1 - 0.18 12.0 3.4 0.3 11.3 0.4 2.9 3 0 0 3 3 3 0 Paired amphipathic helix repeat Pkinase PF00069.25 EGG22965.1 - 5.3e-26 91.6 1.1 2.3e-24 86.2 1.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG22965.1 - 4.3e-16 59.0 0.1 7e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG22965.1 - 0.057 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF2718 PF10918.8 EGG22965.1 - 0.1 13.1 0.2 2.7 8.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) Rhodanese PF00581.20 EGG22966.1 - 8.4e-09 35.9 0.0 2e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain CPSF100_C PF13299.6 EGG22966.1 - 0.0036 17.5 2.6 0.0095 16.1 1.4 1.9 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal BNR_3 PF13859.6 EGG22966.1 - 0.017 14.4 0.4 0.024 13.9 0.4 1.2 1 0 0 1 1 1 0 BNR repeat-like domain Peptidase_U57 PF05582.12 EGG22966.1 - 0.15 11.3 2.9 0.22 10.7 2.9 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Fz PF01392.22 EGG22967.1 - 0.0043 17.6 0.8 0.0081 16.8 0.8 1.4 1 0 0 1 1 1 1 Fz domain DPM3 PF08285.11 EGG22967.1 - 0.31 11.3 3.4 0.29 11.4 0.5 2.5 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) RTTN_N PF14726.6 EGG22968.1 - 0.033 15.0 1.9 6 7.7 0.1 3.0 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning FANCI_S2 PF14676.6 EGG22968.1 - 0.3 11.4 2.0 4.2 7.6 0.0 3.4 2 1 1 4 4 4 0 FANCI solenoid 2 DNApol_Exo PF18136.1 EGG22970.1 - 0.042 13.0 0.2 0.049 12.8 0.2 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain CPP1-like PF11833.8 EGG22970.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like UTP15_C PF09384.10 EGG22971.1 - 0.32 10.7 4.0 0.49 10.1 0.1 3.3 4 0 0 4 4 4 0 UTP15 C terminal RNA_pol_3_Rpc31 PF11705.8 EGG22972.1 - 0.16 12.2 25.1 0.12 12.6 5.4 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CNDH2_N PF06278.11 EGG22972.1 - 0.35 11.1 0.1 0.35 11.1 0.1 3.4 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Cwf_Cwc_15 PF04889.12 EGG22972.1 - 1.1 8.9 27.1 0.36 10.5 9.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 EGG22972.1 - 1.9 8.4 24.3 0.38 10.7 3.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 EGG22972.1 - 9 5.5 30.7 2.2 7.5 11.5 2.2 2 0 0 2 2 2 0 NOA36 protein GatB_Yqey PF02637.18 EGG22977.1 - 0.031 14.1 0.2 0.29 11.0 0.0 2.5 2 0 0 2 2 2 0 GatB domain BP28CT PF08146.12 EGG22977.1 - 0.13 12.1 1.6 0.4 10.5 0.5 2.3 2 0 0 2 2 2 0 BP28CT (NUC211) domain FANCI_S2 PF14676.6 EGG22979.1 - 0.57 10.5 2.7 3.5 7.9 0.2 3.3 1 1 3 4 4 4 0 FANCI solenoid 2 TetR_C_8 PF14278.6 EGG22981.1 - 0.069 13.3 4.0 8 6.6 0.1 3.5 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region Cryptochrome_C PF12546.8 EGG22982.1 - 0.024 15.2 0.4 0.039 14.6 0.0 1.6 2 0 0 2 2 2 0 Blue/Ultraviolet sensing protein C terminal HCNGP PF07818.13 EGG22983.1 - 0.15 12.8 0.6 1 10.0 0.0 2.2 2 1 0 2 2 2 0 HCNGP-like protein FANCI_S2 PF14676.6 EGG22984.1 - 2.1 8.6 7.0 5.4 7.3 0.1 4.4 2 2 3 5 5 5 0 FANCI solenoid 2 DNase_II PF03265.15 EGG22986.1 - 5.4e-10 39.1 0.5 6.7e-10 38.8 0.5 1.1 1 0 0 1 1 1 1 Deoxyribonuclease II DUF3629 PF12302.8 EGG22986.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) FadR_C PF07840.12 EGG22987.1 - 0.038 13.9 0.1 0.056 13.3 0.1 1.4 1 1 0 1 1 1 0 FadR C-terminal domain MACPF PF01823.19 EGG22988.1 - 2.7e-08 34.2 0.1 2.7e-08 34.2 0.1 2.9 2 1 0 2 2 2 1 MAC/Perforin domain KRE9 PF05390.11 EGG22988.1 - 0.76 10.6 8.0 1.5 9.6 0.8 3.4 3 0 0 3 3 3 0 Yeast cell wall synthesis protein KRE9/KNH1 Orf78 PF06024.12 EGG22988.1 - 1.3 9.4 9.0 2.7 8.3 9.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) rve PF00665.26 EGG22990.1 - 7.1e-05 23.0 0.0 0.00022 21.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain ABC2_membrane_3 PF12698.7 EGG22991.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein MACPF PF01823.19 EGG22992.1 - 3.3e-14 53.5 6.8 9.4e-14 52.0 5.5 2.5 1 1 0 1 1 1 1 MAC/Perforin domain MACPF PF01823.19 EGG22993.1 - 7e-25 88.4 1.8 7e-25 88.4 1.8 2.9 2 1 0 2 2 2 1 MAC/Perforin domain Chlam_PMP PF02415.17 EGG22993.1 - 0.02 15.3 2.6 0.061 13.8 1.0 2.9 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF5424 PF17462.2 EGG22995.1 - 0.035 14.0 3.8 0.77 9.7 0.8 2.1 1 1 0 2 2 2 0 Family of unknown function (DUF5424) HEPN_LA2681 PF18733.1 EGG22995.1 - 0.04 13.2 0.6 0.042 13.2 0.6 1.3 1 1 0 1 1 1 0 LA2681-like HEPN Ank_4 PF13637.6 EGG22997.1 - 0.00087 19.8 1.3 11 6.8 0.0 5.2 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG22997.1 - 0.0068 16.7 5.6 13 6.2 0.0 5.9 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG22997.1 - 0.041 14.5 15.3 0.65 10.6 0.0 6.1 4 1 3 7 7 7 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG22997.1 - 0.053 14.1 7.7 78 4.4 0.2 6.3 6 0 0 6 6 6 0 Ankyrin repeat Ctf8 PF09696.10 EGG22998.1 - 2.9e-08 34.1 1.0 4.8e-07 30.2 0.5 2.2 1 1 1 2 2 2 1 Ctf8 Macoilin PF09726.9 EGG22998.1 - 0.26 9.8 3.6 0.27 9.7 3.6 1.0 1 0 0 1 1 1 0 Macoilin family TipE PF16972.5 EGG22998.1 - 0.3 10.2 7.5 0.36 10.0 7.5 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE ECH_2 PF16113.5 EGG22999.1 - 8.3e-120 400.3 0.0 1e-119 400.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGG22999.1 - 4.2e-24 85.2 0.0 3.1e-23 82.4 0.0 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase XRCC4 PF06632.12 EGG23000.1 - 1.4e-28 99.7 16.7 1.8e-28 99.4 16.0 1.6 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PKcGMP_CC PF16808.5 EGG23000.1 - 0.02 14.7 3.3 0.038 13.9 3.3 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TSC22 PF01166.18 EGG23000.1 - 2.3 8.6 8.3 6.1 7.2 2.3 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4407 PF14362.6 EGG23000.1 - 2.8 7.2 7.6 0.25 10.6 3.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 EGG23000.1 - 3.9 7.6 11.5 5.3 7.2 0.2 2.8 2 0 0 2 2 2 0 bZIP transcription factor Ank_2 PF12796.7 EGG23001.1 - 1.1e-15 57.9 5.1 8.3e-09 35.9 0.0 3.6 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG23001.1 - 2.2e-08 34.5 0.0 0.0033 18.0 0.0 5.1 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23001.1 - 1.2e-07 31.4 0.6 13 6.8 0.0 7.3 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 EGG23001.1 - 0.0061 16.9 0.0 93 3.5 0.0 5.1 4 2 2 6 6 6 0 Ankyrin repeats (many copies) DUF4891 PF16232.5 EGG23001.1 - 0.072 13.6 1.1 6.8 7.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4891) AbiJ_NTD4 PF18863.1 EGG23001.1 - 0.11 13.0 0.2 0.21 12.0 0.2 1.5 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 SHQ1 PF04925.15 EGG23002.1 - 9.8e-65 217.4 5.6 1.8e-64 216.6 5.6 1.4 1 0 0 1 1 1 1 SHQ1 protein DUF1797 PF08796.10 EGG23002.1 - 0.48 10.5 3.4 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) CTK3 PF12243.8 EGG23003.1 - 0.0036 17.3 3.0 1.1 9.2 0.8 3.2 2 0 0 2 2 2 2 CTD kinase subunit gamma CTK3 FolB PF02152.18 EGG23003.1 - 0.017 15.7 0.1 0.058 14.0 0.1 1.9 1 0 0 1 1 1 0 Dihydroneopterin aldolase RasGEF_N_2 PF14663.6 EGG23003.1 - 0.044 14.2 2.7 0.11 12.9 0.1 3.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CNOT11 PF10155.9 EGG23004.1 - 0.12 12.6 1.3 7.2 6.8 0.0 3.2 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 DUF4485 PF14846.6 EGG23004.1 - 0.12 12.4 2.1 0.36 10.9 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4485) Arm PF00514.23 EGG23005.1 - 3.1e-58 192.2 17.9 4.9e-13 48.6 0.0 9.5 10 0 0 10 10 10 7 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGG23005.1 - 4.5e-17 62.2 0.4 0.038 14.5 0.0 6.2 4 2 2 6 6 6 5 HEAT-like repeat HEAT_2 PF13646.6 EGG23005.1 - 1.3e-14 54.3 0.1 0.0095 16.3 0.0 4.9 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.22 EGG23005.1 - 6.1e-12 44.7 1.7 0.044 14.1 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat Atx10homo_assoc PF09759.9 EGG23005.1 - 5.5e-08 32.8 0.4 0.69 10.0 0.1 3.5 3 0 0 3 3 3 3 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.6 EGG23005.1 - 9.9e-06 25.7 2.6 7.5 6.9 0.0 5.4 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 EGG23005.1 - 2.4e-05 24.0 0.4 0.17 11.4 0.0 3.5 2 2 2 4 4 4 2 Armadillo-like Cnd1 PF12717.7 EGG23005.1 - 0.00017 21.7 0.0 0.23 11.5 0.0 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF2336 PF10098.9 EGG23005.1 - 0.19 11.2 0.1 7.1 6.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2336) DNA_pol_phi PF04931.13 EGG23005.1 - 0.86 7.6 19.2 5.1 5.1 18.1 2.1 2 0 0 2 2 2 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 EGG23005.1 - 4.2 7.0 10.9 6.3 6.4 10.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ThiF PF00899.21 EGG23006.1 - 1.6e-106 355.1 0.0 4.6e-69 232.5 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGG23006.1 - 5.9e-92 308.1 0.4 1.2e-91 307.1 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EGG23006.1 - 1.2e-31 109.3 0.4 2.9e-31 108.0 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 EGG23006.1 - 7.2e-30 103.0 0.6 2.4e-29 101.3 0.4 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EGG23006.1 - 1e-19 70.5 0.4 3.1e-19 68.9 0.4 2.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle tRNA_m1G_MT PF01746.21 EGG23006.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase NAD_binding_7 PF13241.6 EGG23006.1 - 0.067 13.6 0.1 0.74 10.3 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding SRP54 PF00448.22 EGG23008.1 - 7.7e-75 250.8 0.4 1.2e-74 250.2 0.4 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EGG23008.1 - 5.9e-27 94.2 5.4 5.9e-27 94.2 5.4 3.5 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 EGG23008.1 - 3.1e-12 46.5 0.4 7e-12 45.4 0.4 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EGG23008.1 - 4.5e-05 23.1 0.7 0.00056 19.5 0.7 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGG23008.1 - 0.00025 21.2 0.0 0.00044 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 EGG23008.1 - 0.00045 19.7 0.8 0.32 10.4 0.1 2.3 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGG23008.1 - 0.00059 19.9 0.1 0.0021 18.1 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.23 EGG23008.1 - 0.00065 19.8 0.0 0.0027 17.7 0.0 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EGG23008.1 - 0.00075 19.9 0.0 0.0019 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EGG23008.1 - 0.00099 18.9 3.7 0.0091 15.7 0.1 2.7 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 EGG23008.1 - 0.0024 18.3 0.1 0.0076 16.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EGG23008.1 - 0.0041 16.1 0.1 0.011 14.8 0.1 1.7 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 EGG23008.1 - 0.015 15.2 0.1 0.051 13.5 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 EGG23008.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 EGG23008.1 - 0.028 14.7 0.3 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGG23008.1 - 0.053 13.4 2.2 4.1 7.3 2.2 2.4 1 1 0 1 1 1 0 NTPase DUF2209 PF09974.9 EGG23008.1 - 0.058 13.7 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) AAA_28 PF13521.6 EGG23008.1 - 0.079 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 EGG23008.1 - 0.098 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.21 EGG23008.1 - 0.11 11.9 0.2 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.29 EGG23008.1 - 0.14 12.5 1.1 1.5 9.3 1.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CUT PF02376.15 EGG23008.1 - 0.15 12.2 0.3 26 5.0 0.0 2.8 3 0 0 3 3 2 0 CUT domain Kelch_4 PF13418.6 EGG23009.1 - 0.0002 21.3 1.3 0.5 10.4 0.2 3.8 3 0 0 3 3 3 1 Galactose oxidase, central domain zf-B_box PF00643.24 EGG23009.1 - 0.001 19.1 15.2 0.0026 17.9 15.2 1.7 1 0 0 1 1 1 1 B-box zinc finger Kelch_1 PF01344.25 EGG23009.1 - 0.11 12.1 5.2 12 5.6 0.2 4.4 4 0 0 4 4 4 0 Kelch motif Endonuc_subdom PF09062.10 EGG23009.1 - 0.68 10.8 5.6 0.46 11.4 0.2 3.0 3 0 0 3 3 3 0 PI-PfuI Endonuclease subdomain AT_hook PF02178.19 EGG23009.1 - 3.9 7.7 20.9 0.91 9.6 6.3 2.5 2 0 0 2 2 2 0 AT hook motif SIS PF01380.22 EGG23010.1 - 1.9e-08 34.3 0.9 3.5e-06 26.9 0.3 2.9 2 1 0 2 2 2 2 SIS domain CST-I PF06002.12 EGG23010.1 - 0.1 12.4 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Alpha-2,3-sialyltransferase (CST-I) Dynamin_N PF00350.23 EGG23011.1 - 9.2e-24 84.4 3.8 1e-11 45.2 0.0 3.7 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.23 EGG23011.1 - 6.7e-14 51.9 0.1 3.9e-12 46.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase IIGP PF05049.13 EGG23011.1 - 2.9e-06 26.6 0.9 0.018 14.1 0.0 2.8 3 0 0 3 3 3 2 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.27 EGG23011.1 - 7.4e-06 25.6 0.0 2.4e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGG23011.1 - 2e-05 24.6 2.3 0.096 12.6 0.5 3.0 1 1 1 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGG23011.1 - 0.00012 21.6 0.0 0.15 11.6 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B Roc PF08477.13 EGG23011.1 - 0.0013 19.0 2.3 0.0025 18.0 0.0 2.7 2 2 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGG23011.1 - 0.019 14.8 2.4 0.34 10.7 0.0 3.3 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein DUF1863 PF08937.11 EGG23011.1 - 0.092 13.1 6.0 2.8 8.3 0.3 2.9 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) DUF5470 PF17564.2 EGG23011.1 - 0.89 9.8 10.5 2 8.7 9.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5470) Peptidase_S28 PF05577.12 EGG23012.1 - 1.5e-121 406.3 5.3 1.7e-121 406.0 5.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 EGG23012.1 - 6.8e-06 25.0 0.0 1.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 EGG23012.1 - 2.4e-05 24.1 0.1 5e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG23012.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGG23012.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Transp_cyt_pur PF02133.15 EGG23012.1 - 0.12 11.2 0.8 0.17 10.7 0.8 1.2 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin Hist_deacetyl PF00850.19 EGG23015.1 - 5.2e-76 256.1 0.1 9.2e-76 255.2 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Zn_Tnp_IS1 PF03811.13 EGG23015.1 - 0.026 14.2 3.0 0.061 13.1 3.0 1.6 1 0 0 1 1 1 0 InsA N-terminal domain FHIPEP PF00771.20 EGG23016.1 - 0.023 13.2 9.1 0.27 9.6 0.7 2.4 2 0 0 2 2 2 0 FHIPEP family Androgen_recep PF02166.16 EGG23016.1 - 0.035 13.0 7.5 0.069 12.0 7.5 1.4 1 0 0 1 1 1 0 Androgen receptor Ndc1_Nup PF09531.10 EGG23016.1 - 0.55 8.9 17.9 0.21 10.2 9.6 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Eaf7 PF07904.13 EGG23018.1 - 1.9e-05 24.9 0.0 5.4e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Serglycin PF04360.12 EGG23018.1 - 0.25 11.3 2.4 0.43 10.5 2.4 1.4 1 0 0 1 1 1 0 Serglycin RRM_1 PF00076.22 EGG23019.1 - 0.00036 20.3 0.0 0.0008 19.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Complex1_LYR PF05347.15 EGG23021.1 - 0.00049 20.1 0.3 0.0019 18.2 0.0 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Mito_carr PF00153.27 EGG23022.1 - 5.2e-70 231.4 2.2 3.1e-24 84.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Xpo1 PF08389.12 EGG23023.1 - 2.6e-12 47.0 0.2 2.6e-12 47.0 0.2 5.7 5 2 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 EGG23023.1 - 5.7e-05 23.0 5.4 0.00036 20.4 0.4 3.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain CRM1_C PF08767.11 EGG23023.1 - 0.042 13.0 19.7 0.017 14.3 1.3 3.5 2 1 0 2 2 2 0 CRM1 C terminal DUF4508 PF14969.6 EGG23023.1 - 0.11 12.8 2.4 11 6.4 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) DUF960 PF06124.11 EGG23023.1 - 0.3 11.7 3.5 0.58 10.8 0.9 2.8 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) DUF1041 PF06292.17 EGG23023.1 - 0.46 10.9 3.4 11 6.5 0.1 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1041) PHF5 PF03660.14 EGG23024.1 - 1.4e-50 169.9 14.1 1.5e-50 169.7 14.1 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EGG23024.1 - 0.042 11.7 8.7 0.045 11.6 8.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EGG23024.1 - 3.6 7.7 16.0 10 6.3 2.1 2.9 1 1 1 2 2 2 0 Double zinc ribbon N_BRCA1_IG PF16158.5 EGG23025.1 - 4.2e-20 72.4 1.1 3.8e-19 69.3 0.0 3.3 3 0 0 3 3 3 1 Ig-like domain from next to BRCA1 gene CooT PF10133.9 EGG23025.1 - 0.0023 18.2 0.1 0.0059 16.9 0.1 1.7 1 0 0 1 1 1 1 CO dehydrogenase accessory protein CooT ZZ PF00569.17 EGG23025.1 - 0.0026 17.5 8.5 0.0086 15.9 8.5 1.9 1 0 0 1 1 1 1 Zinc finger, ZZ type RPA43_OB PF17875.1 EGG23026.1 - 0.4 11.3 6.4 0.43 11.2 6.4 1.0 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DUF3682 PF12446.8 EGG23026.1 - 4.8 7.7 15.5 5.4 7.5 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Connexin PF00029.19 EGG23026.1 - 5.3 6.7 7.3 5 6.8 7.3 1.0 1 0 0 1 1 1 0 Connexin OATP PF03137.20 EGG23026.1 - 7.3 4.7 6.4 7.1 4.8 6.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RasGEF PF00617.19 EGG23027.1 - 6.6e-29 101.4 0.2 6.6e-29 101.4 0.2 2.2 2 0 0 2 2 2 1 RasGEF domain RhoGAP PF00620.27 EGG23027.1 - 1.6e-16 60.5 0.0 6e-16 58.6 0.0 2.1 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.20 EGG23027.1 - 1.3e-13 51.1 3.7 3.2e-13 49.8 0.1 3.0 2 0 0 2 2 2 1 RasGEF N-terminal motif HU-HIG PF18291.1 EGG23027.1 - 0.0027 17.8 0.5 0.024 14.7 0.0 2.7 3 0 0 3 3 3 1 HU domain fused to wHTH, Ig, or Glycine-rich motif DUF4471 PF14740.6 EGG23027.1 - 0.35 10.0 19.0 0.26 10.5 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4471) Holin_BhlA PF10960.8 EGG23027.1 - 1.9 8.5 6.6 5.8 7.0 6.6 1.8 1 0 0 1 1 1 0 BhlA holin family Ribosomal_S2 PF00318.20 EGG23027.1 - 2.5 7.3 7.6 8.1 5.6 7.6 1.9 1 0 0 1 1 1 0 Ribosomal protein S2 EGF_2 PF07974.13 EGG23028.1 - 0.01 16.2 27.3 0.052 13.9 9.4 2.6 2 0 0 2 2 2 0 EGF-like domain Insulin_TMD PF17870.1 EGG23028.1 - 0.043 13.9 0.7 0.13 12.3 0.7 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment hEGF PF12661.7 EGG23028.1 - 0.39 11.4 24.0 0.6 10.8 8.5 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.13 EGG23029.1 - 0.65 10.4 29.8 0.06 13.7 9.4 2.6 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 EGG23029.1 - 0.69 10.6 23.7 0.52 11.0 8.5 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.13 EGG23030.1 - 5.3 7.5 13.7 9.9 6.6 13.7 1.5 1 0 0 1 1 1 0 EGF-like domain DUF3844 PF12955.7 EGG23030.1 - 8.5 6.6 10.1 1.4 9.0 5.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) EGF_2 PF07974.13 EGG23031.1 - 0.0019 18.5 46.0 0.097 13.1 9.3 3.6 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 EGG23031.1 - 0.044 14.4 42.2 0.78 10.5 8.5 4.0 3 0 0 3 3 3 0 Human growth factor-like EGF DUF2850 PF11012.8 EGG23031.1 - 0.22 11.9 1.7 19 5.6 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2850) Glyco_hydro_5_C PF18564.1 EGG23031.1 - 0.29 11.7 4.7 52 4.5 0.1 4.8 4 0 0 4 4 4 0 Glycoside hydrolase family 5 C-terminal domain HicB_lk_antitox PF15919.5 EGG23031.1 - 0.35 11.0 3.2 12 6.0 0.3 2.8 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system HisKA_4TM PF16926.5 EGG23031.1 - 0.38 10.3 1.7 20 4.7 0.2 2.4 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase DUF3042 PF11240.8 EGG23031.1 - 7.3 6.7 9.7 7.4 6.7 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DDE_Tnp_1_7 PF13843.6 EGG23032.1 - 2.2e-28 99.6 4.2 1.5e-27 96.9 4.2 2.3 1 1 0 1 1 1 1 Transposase IS4 DUF4999 PF16390.5 EGG23032.1 - 0.12 12.6 0.5 0.52 10.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function PHD_2 PF13831.6 EGG23032.1 - 2.8 7.6 8.0 0.073 12.6 1.4 1.7 2 0 0 2 2 2 0 PHD-finger PAH PF02671.21 EGG23033.1 - 0.0033 17.5 0.2 0.015 15.5 0.2 2.1 1 0 0 1 1 1 1 Paired amphipathic helix repeat fn3 PF00041.21 EGG23036.1 - 1.1e-05 25.6 5.9 0.0027 18.0 0.6 5.4 5 0 0 5 5 5 1 Fibronectin type III domain DUF2369 PF10179.9 EGG23036.1 - 0.46 10.9 3.9 0.94 9.9 0.2 3.2 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) VESA1_N PF12785.7 EGG23037.1 - 0.0029 16.7 10.1 0.0044 16.1 10.1 1.3 1 0 0 1 1 1 1 Variant erythrocyte surface antigen-1 PBP1_TM PF14812.6 EGG23037.1 - 0.022 15.1 3.6 0.022 15.1 3.6 3.2 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Opi1 PF08618.10 EGG23037.1 - 1 8.5 8.1 1.8 7.7 8.1 1.3 1 0 0 1 1 1 0 Transcription factor Opi1 LRR_4 PF12799.7 EGG23038.1 - 0.0013 19.1 2.4 1.8 9.1 0.3 4.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) EGF_2 PF07974.13 EGG23038.1 - 0.074 13.4 28.4 0.071 13.5 9.3 2.6 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 EGG23038.1 - 0.29 11.8 24.3 0.57 10.9 8.5 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF CarboxypepD_reg PF13620.6 EGG23038.1 - 0.88 9.9 5.8 0.19 12.0 0.7 2.6 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Hormone_5 PF00184.17 EGG23038.1 - 10 7.1 15.7 2.2 9.2 4.0 2.8 2 0 0 2 2 2 0 Neurohypophysial hormones, C-terminal Domain LRR_8 PF13855.6 EGG23039.1 - 0.093 12.5 0.8 22 4.9 0.1 3.2 2 0 0 2 2 2 0 Leucine rich repeat EGF_2 PF07974.13 EGG23039.1 - 0.11 12.8 29.2 0.076 13.4 9.3 2.6 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 EGG23039.1 - 0.25 12.0 24.5 0.61 10.8 8.5 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF Amino_oxidase PF01593.24 EGG23040.1 - 1.2e-59 202.8 0.0 1.7e-59 202.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGG23040.1 - 2.1e-14 53.5 0.1 4.2e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG23040.1 - 6.7e-09 35.8 0.5 1.8e-05 24.5 0.3 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGG23040.1 - 2.2e-06 27.3 0.0 3.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGG23040.1 - 6.7e-06 25.4 0.3 1e-05 24.9 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGG23040.1 - 7.7e-06 25.3 0.1 5.3e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGG23040.1 - 1e-05 26.0 0.6 0.00055 20.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGG23040.1 - 2.9e-05 23.4 0.0 4.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EGG23040.1 - 3.3e-05 23.1 0.2 0.012 14.7 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 EGG23040.1 - 4.5e-05 22.3 0.2 0.0001 21.2 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EGG23040.1 - 0.0003 20.2 0.6 0.0028 17.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain GDI PF00996.18 EGG23040.1 - 0.0026 16.4 0.0 0.0042 15.7 0.0 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor Thi4 PF01946.17 EGG23040.1 - 0.0038 16.5 0.2 0.007 15.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EGG23040.1 - 0.13 12.2 0.6 14 5.6 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGG23040.1 - 0.22 10.7 0.3 0.45 9.7 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FPL PF09758.9 EGG23042.1 - 9.1e-54 181.5 10.7 9.1e-54 181.5 10.7 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein Glycos_transf_2 PF00535.26 EGG23043.1 - 2.3e-15 56.8 0.1 1.4e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 EGG23043.1 - 0.00021 21.8 0.0 0.0012 19.3 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EGG23043.1 - 0.00085 18.9 0.8 0.044 13.2 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 CoA_binding PF02629.19 EGG23043.1 - 0.087 13.5 0.0 0.27 11.9 0.0 1.8 1 0 0 1 1 1 0 CoA binding domain MACPF PF01823.19 EGG23044.1 - 1.5e-21 77.5 1.4 3.9e-21 76.1 1.4 1.7 1 0 0 1 1 1 1 MAC/Perforin domain MACPF PF01823.19 EGG23045.1 - 1e-21 78.0 0.3 2.6e-21 76.7 0.2 1.7 1 1 0 1 1 1 1 MAC/Perforin domain PhyH PF05721.13 EGG23046.1 - 3.2e-06 27.6 0.1 0.00039 20.8 0.1 2.5 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) RhoGAP PF00620.27 EGG23047.1 - 5.1e-31 107.6 0.1 2.4e-30 105.4 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain NARG2_C PF10505.9 EGG23047.1 - 7.7e-23 81.1 0.1 1.8e-22 79.9 0.1 1.6 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus RPEL PF02755.15 EGG23047.1 - 0.0019 17.8 0.4 0.0053 16.4 0.0 2.0 2 0 0 2 2 2 1 RPEL repeat DAP PF15228.6 EGG23048.1 - 0.04 15.1 8.3 0.11 13.7 8.3 1.7 1 1 0 1 1 1 0 Death-associated protein CLTH PF10607.9 EGG23049.1 - 8.3e-26 90.6 0.0 8.3e-26 90.6 0.0 2.2 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EGG23049.1 - 0.00035 20.5 1.1 0.00069 19.6 1.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG23049.1 - 0.064 13.2 0.5 0.15 12.0 0.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EGG23049.1 - 0.093 13.1 0.8 0.19 12.1 0.8 1.5 1 0 0 1 1 1 0 Ring finger domain L31 PF09784.9 EGG23049.1 - 0.27 11.7 2.1 1.7 9.1 2.1 2.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 CDC50 PF03381.15 EGG23050.1 - 1.4e-91 306.9 0.4 1.4e-91 306.9 0.4 1.4 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.8 EGG23050.1 - 2.4 8.2 4.7 5 7.2 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Ribosomal_L13 PF00572.18 EGG23051.1 - 4.2e-47 159.5 0.1 7.3e-47 158.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 hGDE_N PF14699.6 EGG23053.1 - 0.022 14.9 0.7 0.12 12.6 0.1 2.6 3 0 0 3 3 3 0 N-terminal domain from the human glycogen debranching enzyme Proteasome PF00227.26 EGG23054.1 - 8.7e-57 191.7 0.1 1.1e-56 191.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGG23054.1 - 1e-13 50.7 0.0 1.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PAC3 PF10178.9 EGG23055.1 - 2.6e-23 82.0 0.0 4.1e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Glyco_hydro_20 PF00728.22 EGG23056.1 - 1.9e-19 70.3 0.1 3.6e-18 66.1 0.0 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 EGG23056.1 - 0.007 17.1 0.0 0.018 15.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 EGG23056.1 - 0.024 15.3 1.4 0.047 14.3 0.1 2.2 2 1 0 2 2 2 0 beta-acetyl hexosaminidase like CBS PF00571.28 EGG23057.1 - 2.7e-24 85.4 2.2 6.8e-10 39.2 0.1 4.4 4 0 0 4 4 4 4 CBS domain DUF2951 PF11166.8 EGG23057.1 - 0.068 13.4 1.4 0.17 12.1 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Acid_phosphat_B PF03767.14 EGG23059.1 - 0.057 13.0 0.3 0.067 12.8 0.3 1.1 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF5021 PF16424.5 EGG23059.1 - 0.15 11.9 1.9 0.22 11.3 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5021) Pkinase PF00069.25 EGG23060.1 - 6.6e-71 238.8 1.2 9e-71 238.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23060.1 - 4.8e-38 130.9 0.0 8.1e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EGG23060.1 - 9.7e-08 31.7 0.2 2.6e-07 30.3 0.2 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 APH PF01636.23 EGG23060.1 - 3.1e-06 27.3 0.0 0.016 15.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGG23060.1 - 3.2e-05 23.4 0.0 6.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGG23060.1 - 8e-05 21.7 0.0 8e-05 21.7 0.0 2.5 3 0 0 3 3 3 1 Haspin like kinase domain Choline_kinase PF01633.20 EGG23060.1 - 0.02 14.5 0.3 0.02 14.5 0.3 2.5 2 1 1 3 3 3 0 Choline/ethanolamine kinase Kdo PF06293.14 EGG23060.1 - 0.051 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family G-alpha PF00503.20 EGG23061.1 - 4.8e-111 371.3 5.6 6.8e-111 370.8 5.6 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGG23061.1 - 7.2e-15 54.9 0.4 1.4e-11 44.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG23061.1 - 3.4e-06 26.6 1.9 0.00056 19.3 0.2 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGG23061.1 - 1.4e-05 25.3 1.6 0.014 15.6 0.1 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGG23061.1 - 0.04 14.0 0.0 3 8.0 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG23061.1 - 0.078 12.5 0.0 0.47 10.0 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Epimerase PF01370.21 EGG23061.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AAA_29 PF13555.6 EGG23061.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RR_TM4-6 PF06459.12 EGG23066.1 - 0.38 10.5 16.3 0.023 14.5 9.2 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 EGG23066.1 - 2.9 6.7 10.3 4.3 6.1 10.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BSP_II PF05432.11 EGG23066.1 - 3.7 7.2 21.8 0.52 10.0 8.8 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Ribosomal_L12 PF00542.19 EGG23067.1 - 6e-17 61.7 5.2 6e-17 61.7 5.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EGG23067.1 - 9.5e-08 31.6 8.5 9.5e-08 31.6 8.5 3.1 3 1 0 3 3 3 2 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 EGG23067.1 - 0.02 15.5 4.1 0.025 15.2 0.3 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein NUFIP1 PF10453.9 EGG23068.1 - 1.9e-13 50.0 7.2 1.9e-13 50.0 7.2 6.8 5 2 0 5 5 5 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Thioredoxin PF00085.20 EGG23069.1 - 1.6e-22 79.4 0.6 5.4e-17 61.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 EGG23069.1 - 3e-07 30.1 0.0 1.2e-06 28.1 0.0 1.9 1 1 1 2 2 2 1 OST3 / OST6 family, transporter family MMR_HSR1 PF01926.23 EGG23069.1 - 0.033 14.3 0.2 0.62 10.2 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EGG23069.1 - 0.059 13.6 1.6 0.15 12.3 1.6 1.7 1 0 0 1 1 1 0 AAA domain Thioredoxin_7 PF13899.6 EGG23069.1 - 0.08 13.1 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like PMC2NT PF08066.12 EGG23069.1 - 0.11 13.1 3.1 0.17 12.6 0.1 2.8 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Menin PF05053.13 EGG23069.1 - 0.52 8.6 12.2 0.88 7.8 4.5 2.3 2 0 0 2 2 2 0 Menin SelP_N PF04592.14 EGG23069.1 - 0.99 8.8 6.9 3.4 7.0 3.6 2.9 3 0 0 3 3 3 0 Selenoprotein P, N terminal region TFIIA PF03153.13 EGG23069.1 - 4.4 7.2 19.5 2.8 7.8 10.7 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SAM_PNT PF02198.16 EGG23070.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Macoilin PF09726.9 EGG23071.1 - 5 5.6 19.9 6.4 5.2 19.9 1.3 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 EGG23072.1 - 1.1e-47 162.7 0.1 1.1e-47 162.7 0.1 3.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23072.1 - 4.6e-16 58.9 0.1 4.6e-16 58.9 0.1 3.2 3 1 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 EGG23072.1 - 0.032 14.1 0.1 0.032 14.1 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Endotoxin_N PF03945.14 EGG23073.1 - 7.1e-05 22.6 0.0 0.26 11.0 0.0 2.3 1 1 1 2 2 2 2 delta endotoxin, N-terminal domain MauJ PF17419.2 EGG23073.1 - 0.086 12.3 0.0 0.81 9.1 0.0 2.0 2 0 0 2 2 2 0 Methylamine utilization protein MauJ CLPTM1 PF05602.12 EGG23074.1 - 0.01 14.9 0.7 0.014 14.5 0.7 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Na_H_antiport_3 PF07399.11 EGG23074.1 - 0.18 10.7 0.1 0.26 10.1 0.1 1.1 1 0 0 1 1 1 0 Putative Na+/H+ antiporter Glyco_transf_17 PF04724.13 EGG23074.1 - 0.47 9.4 1.7 0.65 9.0 0.6 1.6 1 1 1 2 2 2 0 Glycosyltransferase family 17 EGF_2 PF07974.13 EGG23077.1 - 0.013 15.9 8.0 0.013 15.9 8.0 2.6 2 0 0 2 2 2 0 EGF-like domain DUF3042 PF11240.8 EGG23077.1 - 0.62 10.1 2.4 1.4 9.0 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) S4 PF01479.25 EGG23078.1 - 2.5e-12 46.3 0.7 5.6e-12 45.2 0.7 1.6 1 0 0 1 1 1 1 S4 domain zf-CCHC PF00098.23 EGG23079.1 - 0.00089 19.2 2.2 0.0012 18.8 2.2 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGG23079.1 - 0.04 13.9 0.2 0.058 13.4 0.2 1.2 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 EGG23079.1 - 0.066 12.9 0.4 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RRM_1 PF00076.22 EGG23080.1 - 3.9e-28 97.1 6.0 4.7e-15 55.2 0.3 3.5 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG23080.1 - 2e-07 31.0 3.0 0.00067 19.7 0.6 2.8 1 1 1 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 EGG23080.1 - 8.9e-07 28.8 1.1 0.00035 20.4 0.2 2.8 1 1 1 2 2 2 2 Rrp7 RRM-like N-terminal domain BRAP2 PF07576.12 EGG23080.1 - 0.01 16.0 0.0 0.67 10.2 0.0 2.6 2 1 0 2 2 2 0 BRCA1-associated protein 2 TPR_3 PF07720.12 EGG23080.1 - 5.4 7.1 5.3 0.74 9.9 0.6 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2804 PF10974.8 EGG23081.1 - 1.6e-104 350.0 0.9 2e-104 349.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) Cation_ATPase_C PF00689.21 EGG23082.1 - 3.1e-46 157.4 6.8 3.1e-46 157.4 6.8 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGG23082.1 - 3.6e-35 121.1 2.0 3.6e-35 121.1 2.0 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGG23082.1 - 7.2e-23 80.5 0.0 1.3e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGG23082.1 - 5.3e-19 69.3 0.9 7.1e-18 65.7 0.9 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGG23082.1 - 3.2e-13 49.1 0.0 6.4e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG23082.1 - 0.0096 15.7 2.1 0.016 14.9 0.3 2.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Colicin_im PF03857.13 EGG23082.1 - 0.02 14.8 1.8 0.051 13.5 1.8 1.6 1 0 0 1 1 1 0 Colicin immunity protein GMC_oxred_N PF00732.19 EGG23083.1 - 7.5e-44 150.3 0.1 2.5e-43 148.6 0.1 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGG23083.1 - 2.7e-29 102.6 0.0 4.6e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EGG23083.1 - 0.0018 18.4 0.3 0.0044 17.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGG23083.1 - 0.064 12.0 0.1 0.25 10.0 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EGG23083.1 - 0.28 10.4 0.8 0.51 9.5 0.8 1.3 1 0 0 1 1 1 0 Thi4 family TIG PF01833.24 EGG23084.1 - 8.5e-08 32.2 0.7 8.5e-08 32.2 0.7 3.4 3 1 0 3 3 3 1 IPT/TIG domain CTV_P6 PF06706.11 EGG23084.1 - 0.069 12.9 1.7 0.19 11.5 1.7 1.8 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein MtrF PF09472.10 EGG23084.1 - 0.1 12.0 3.2 0.22 11.0 3.2 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) EGF_Tenascin PF18720.1 EGG23084.1 - 0.14 12.2 15.1 0.5 10.5 15.1 2.0 1 0 0 1 1 1 0 Tenascin EGF domain EGF_2 PF07974.13 EGG23084.1 - 3.7 8.0 21.0 0.2 12.0 15.5 1.8 2 0 0 2 2 2 0 EGF-like domain Sdh5 PF03937.16 EGG23085.1 - 2.5e-24 85.0 0.1 4.3e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase HSP70 PF00012.20 EGG23087.1 - 1.1e-247 823.0 6.6 1.4e-247 822.8 6.6 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGG23087.1 - 3.8e-14 52.3 0.9 4.5e-11 42.1 0.1 2.8 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EGG23087.1 - 0.00058 19.7 0.0 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EGG23087.1 - 0.0013 19.2 3.7 12 6.4 0.0 4.1 3 1 0 3 3 3 2 Cell division protein FtsA QRPTase_C PF01729.19 EGG23087.1 - 0.14 11.9 4.2 0.96 9.2 0.1 3.1 2 1 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain Mannitol_dh PF01232.23 EGG23088.1 - 3.6 7.7 8.9 1.6 8.9 5.6 2.1 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain LMBR1 PF04791.16 EGG23088.1 - 9.9 4.9 8.3 16 4.2 8.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein KTI12 PF08433.10 EGG23091.1 - 6e-20 71.8 7.1 6.9e-13 48.7 6.0 2.1 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_33 PF13671.6 EGG23091.1 - 1.5e-06 28.5 0.0 8e-05 22.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGG23091.1 - 0.00025 21.6 2.0 0.00069 20.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain 6PF2K PF01591.18 EGG23091.1 - 0.0022 17.3 2.9 0.0046 16.3 0.0 2.6 3 0 0 3 3 3 1 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 EGG23091.1 - 0.025 14.7 0.2 0.28 11.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EGG23091.1 - 0.043 14.1 0.6 0.14 12.4 0.0 2.2 2 2 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGG23091.1 - 0.056 13.8 1.0 0.24 11.8 0.1 2.5 2 1 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 EGG23091.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MotB_plug PF13677.6 EGG23092.1 - 0.048 13.3 0.4 0.18 11.4 0.4 2.0 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Phage_holin_3_6 PF07332.11 EGG23093.1 - 4.6 7.3 20.5 0.14 12.2 3.0 3.3 1 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Peptidase_S74 PF13884.6 EGG23096.1 - 2e-10 40.8 0.1 4.3e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase TFIIA PF03153.13 EGG23096.1 - 0.0059 16.6 35.8 0.0059 16.6 35.8 4.4 3 1 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit Jiraiya PF15038.6 EGG23096.1 - 0.074 12.5 3.9 0.26 10.7 3.9 1.9 1 0 0 1 1 1 0 Jiraiya Wzy_C PF04932.15 EGG23096.1 - 0.12 11.9 1.7 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 O-Antigen ligase DUF2975 PF11188.8 EGG23096.1 - 0.13 12.1 4.5 0.24 11.3 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF2946 PF11162.8 EGG23096.1 - 0.91 10.2 0.0 0.91 10.2 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2946) Asparaginase_2 PF01112.18 EGG23097.1 - 4.8e-115 383.8 0.7 5.5e-115 383.6 0.7 1.0 1 0 0 1 1 1 1 Asparaginase COG7 PF10191.9 EGG23098.1 - 2.5e-99 333.6 36.0 4.4e-98 329.5 36.0 2.0 1 1 0 1 1 1 1 Golgi complex component 7 (COG7) COG5 PF10392.9 EGG23098.1 - 5.5 7.2 25.7 0.14 12.4 10.2 5.0 4 2 0 4 4 4 0 Golgi transport complex subunit 5 Plus-3 PF03126.18 EGG23099.1 - 4.6e-26 91.5 0.5 6.1e-25 87.9 0.0 2.5 2 0 0 2 2 2 1 Plus-3 domain DicB PF05358.11 EGG23099.1 - 0.16 12.1 0.4 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 DicB protein RmlD_sub_bind PF04321.17 EGG23100.1 - 2.1e-53 181.3 0.0 2.4e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGG23100.1 - 1.1e-18 67.5 0.0 1.6e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG23100.1 - 7.7e-12 45.2 0.1 1.4e-11 44.4 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGG23100.1 - 8.5e-12 44.8 0.2 4.6e-11 42.4 0.2 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGG23100.1 - 5.1e-10 38.8 0.2 6.8e-10 38.4 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGG23100.1 - 0.00036 19.8 1.4 0.0026 17.0 0.1 2.4 1 1 1 2 2 2 1 Male sterility protein DnaJ PF00226.31 EGG23101.1 - 6.8e-23 80.6 5.0 2.1e-22 79.0 5.0 1.9 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EGG23101.1 - 1.2e-18 67.6 0.0 2e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EGG23101.1 - 2.8e-09 37.2 8.4 2.8e-09 37.2 8.4 3.1 2 1 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 EGG23101.1 - 0.00016 21.6 8.3 0.0042 17.0 3.1 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Exonuc_VII_L PF02601.15 EGG23101.1 - 0.0033 17.0 16.5 0.0055 16.3 16.5 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit TFIIA PF03153.13 EGG23101.1 - 0.03 14.3 62.4 0.49 10.3 51.9 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Herpes_capsid PF06112.11 EGG23101.1 - 0.13 12.3 18.0 0.32 11.0 18.0 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ECH_1 PF00378.20 EGG23102.1 - 3.9e-40 137.7 0.0 4.8e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGG23102.1 - 9.6e-16 58.2 0.0 1.4e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pkinase PF00069.25 EGG23103.1 - 6.6e-62 209.3 0.3 4.1e-61 206.7 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23103.1 - 5.5e-41 140.6 0.0 1e-40 139.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG23103.1 - 0.00022 20.6 0.0 0.0005 19.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGG23103.1 - 0.00025 21.0 0.0 0.0018 18.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family FNIP PF05725.12 EGG23104.1 - 1.4e-27 95.6 17.3 1.4e-14 54.0 0.9 7.1 5 1 4 9 9 9 7 FNIP Repeat GYF PF02213.16 EGG23105.1 - 2.8e-10 39.7 3.4 9.8e-10 38.0 3.4 2.0 1 0 0 1 1 1 1 GYF domain eIF3_subunit PF08597.10 EGG23105.1 - 5e-05 23.3 15.7 5e-05 23.3 15.7 1.7 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit GYF_2 PF14237.6 EGG23105.1 - 0.00092 19.0 0.6 0.0024 17.6 0.6 1.7 1 0 0 1 1 1 1 GYF domain 2 Adhesin_P1_N PF18652.1 EGG23105.1 - 0.015 15.3 1.6 0.015 15.3 1.6 3.9 4 1 1 5 5 5 0 Adhesin P1 N-terminal domain Ephrin_rec_like PF07699.13 EGG23106.1 - 9.6e-11 41.3 38.7 5.4e-08 32.5 13.1 10.3 6 2 7 13 13 13 8 Putative ephrin-receptor like NCD3G PF07562.14 EGG23106.1 - 0.028 14.4 58.1 0.32 11.0 2.4 7.2 2 1 5 9 9 9 0 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EGG23106.1 - 2.6 8.5 48.8 0.67 10.4 2.1 8.2 2 2 4 7 7 7 0 TNFR/NGFR cysteine-rich region MMS1_N PF10433.9 EGG23107.1 - 1e-94 317.9 0.3 2.2e-94 316.8 0.3 1.6 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGG23107.1 - 5e-62 210.1 1.0 2.3e-60 204.6 0.4 2.9 3 0 0 3 3 3 2 CPSF A subunit region Dicty_CTDC PF00526.18 EGG23108.1 - 2.2e-16 59.4 47.4 3.6e-07 30.0 10.4 15.0 15 2 0 15 15 15 8 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGG23108.1 - 5.2e-10 39.3 0.1 9.9e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Integrin_b_cyt PF08725.11 EGG23108.1 - 0.59 9.9 3.1 1.4 8.7 3.1 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Metallophos PF00149.28 EGG23112.1 - 1e-20 75.1 1.3 2.2e-20 74.0 1.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EGG23112.1 - 3.3e-13 50.0 7.3 1.4e-06 28.8 3.2 2.8 2 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 EGG23112.1 - 1.8e-10 41.5 0.2 5.2e-10 40.0 0.2 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 EGG23112.1 - 2.5e-07 31.0 0.0 1.3e-05 25.5 0.0 2.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.32 EGG23113.1 - 2.4e-19 69.3 1.4 4.6e-08 33.6 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG23113.1 - 6.2e-08 32.8 0.7 0.05 13.9 0.0 3.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain MMR_HSR1 PF01926.23 EGG23114.1 - 1.9e-12 47.2 0.0 1.9e-12 47.2 0.0 2.7 3 1 1 4 4 4 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG23114.1 - 4.5e-05 23.4 5.2 0.035 14.0 1.8 2.6 2 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGG23114.1 - 0.00014 21.4 0.1 0.00088 18.8 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 EGG23114.1 - 0.0039 16.6 5.0 0.35 10.3 0.2 2.6 3 0 0 3 3 3 2 ADP-ribosylation factor family DUF4207 PF13904.6 EGG23114.1 - 0.02 14.6 6.4 0.04 13.6 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) BSP_II PF05432.11 EGG23114.1 - 0.092 12.4 4.1 0.13 11.9 4.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) AAA_7 PF12775.7 EGG23114.1 - 0.15 11.6 3.2 4 6.9 0.2 2.9 3 1 0 3 3 3 0 P-loop containing dynein motor region DUF4448 PF14610.6 EGG23114.1 - 2.4 7.9 6.4 1.9 8.2 4.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) CRAL_TRIO PF00650.20 EGG23115.1 - 1.6e-35 122.2 0.0 2.2e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGG23115.1 - 8e-10 38.8 1.5 8e-10 38.8 1.5 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGG23115.1 - 1.1e-07 32.1 0.0 1.7e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SF3b1 PF08920.10 EGG23115.1 - 0.049 14.1 1.0 11 6.6 0.0 3.0 3 0 0 3 3 3 0 Splicing factor 3B subunit 1 RRM_1 PF00076.22 EGG23117.1 - 1e-16 60.5 0.0 1.5e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3915 PF13054.6 EGG23118.1 - 0.0043 17.0 4.9 0.0043 17.0 4.9 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3915) Ank_2 PF12796.7 EGG23119.1 - 1.5e-46 156.9 8.1 1.5e-14 54.3 0.0 5.4 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG23119.1 - 1.8e-35 120.9 6.2 6.6e-06 26.6 0.0 6.5 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EGG23119.1 - 8.4e-32 108.2 9.2 1.6e-06 28.3 0.0 9.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EGG23119.1 - 4.4e-26 90.6 6.5 2.1e-07 31.1 0.3 6.9 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23119.1 - 1.9e-23 79.9 6.3 0.0095 16.4 0.0 9.5 10 0 0 10 10 10 4 Ankyrin repeat TPR_12 PF13424.6 EGG23120.1 - 0.00046 20.4 0.8 0.69 10.3 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat zinc_ribbon_15 PF17032.5 EGG23122.1 - 5.4e-09 36.7 0.9 5.4e-09 36.7 0.9 1.6 2 0 0 2 2 2 1 zinc-ribbon family HNH PF01844.23 EGG23122.1 - 0.015 15.5 0.1 0.015 15.5 0.1 1.7 2 0 0 2 2 2 0 HNH endonuclease Lar_restr_allev PF14354.6 EGG23122.1 - 0.019 15.3 1.5 0.042 14.2 1.5 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 EGG23122.1 - 0.49 9.9 4.1 0.71 9.4 0.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Caskin-Pro-rich PF16907.5 EGG23122.1 - 1.4 9.5 5.7 0.64 10.6 3.0 1.8 1 1 1 2 2 2 0 Proline rich region of Caskin proteins zf-RING_2 PF13639.6 EGG23123.1 - 5e-05 23.5 5.4 5e-05 23.5 5.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EGG23123.1 - 0.00055 20.2 5.2 0.00055 20.2 5.2 2.2 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGG23123.1 - 0.028 14.3 5.3 0.028 14.3 5.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG23123.1 - 0.051 13.4 9.2 0.083 12.7 6.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG23123.1 - 0.079 12.8 5.4 0.095 12.6 2.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGG23123.1 - 0.1 12.4 5.5 0.1 12.4 2.9 2.2 2 0 0 2 2 2 0 RING-like zinc finger DZR PF12773.7 EGG23123.1 - 0.14 12.2 1.7 0.71 9.9 1.7 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-ANAPC11 PF12861.7 EGG23123.1 - 0.23 11.5 4.8 0.1 12.6 2.4 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGG23123.1 - 0.72 10.1 7.4 0.54 10.4 3.4 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGG23123.1 - 0.73 9.7 3.3 1.7 8.5 3.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EGG23123.1 - 0.83 9.7 7.2 0.44 10.6 3.8 2.0 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EGG23123.1 - 1.9 8.4 7.2 0.5 10.3 3.8 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EGG23123.1 - 5 6.8 9.6 0.95 9.1 5.3 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type SR-25 PF10500.9 EGG23124.1 - 0.076 12.6 12.7 0.12 12.0 12.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 EGG23124.1 - 4.4 8.1 8.8 8.1 7.2 8.8 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Gpi1 PF05024.15 EGG23125.1 - 4.7e-59 199.6 13.6 1.3e-58 198.2 13.6 1.8 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF3439 PF11921.8 EGG23125.1 - 0.0094 15.9 0.5 0.056 13.4 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Sensor PF13796.6 EGG23125.1 - 4.2 7.4 9.0 4.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Putative sensor F-box-like PF12937.7 EGG23126.1 - 5.7e-10 38.9 1.6 1.2e-09 37.9 1.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG23126.1 - 7.3e-08 32.1 2.3 1.8e-07 30.9 2.3 1.7 1 0 0 1 1 1 1 F-box domain ThuA PF06283.11 EGG23126.1 - 0.033 14.4 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 Trehalose utilisation IBR PF01485.21 EGG23128.1 - 1.1e-19 70.4 33.2 1.2e-13 51.0 5.2 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain UBA PF00627.31 EGG23128.1 - 0.00051 19.9 1.1 0.006 16.5 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain zf-RING_5 PF14634.6 EGG23128.1 - 0.0089 16.0 7.6 0.0089 16.0 7.6 3.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGG23128.1 - 0.013 15.3 4.8 0.013 15.3 4.8 4.7 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) TetR_C_17 PF17922.1 EGG23128.1 - 0.098 12.8 1.9 0.11 12.6 0.2 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PBP1_TM PF14812.6 EGG23128.1 - 0.11 12.8 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-RING_4 PF14570.6 EGG23128.1 - 1.3 8.9 37.1 0.03 14.1 5.3 3.8 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain SPO22 PF08631.10 EGG23129.1 - 0.014 14.9 6.8 0.048 13.1 1.5 2.8 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like zf-UBR PF02207.20 EGG23131.1 - 3.6e-11 43.1 27.7 4.3e-08 33.2 7.3 2.4 2 0 0 2 2 2 2 Putative zinc finger in N-recognin (UBR box) XH PF03469.14 EGG23131.1 - 0.0092 15.9 3.2 0.026 14.4 0.1 3.1 4 0 0 4 4 4 1 XH domain DUF2025 PF09634.10 EGG23131.1 - 0.019 15.0 0.8 0.5 10.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2025) Spectrin PF00435.21 EGG23131.1 - 1.3 9.5 5.7 0.63 10.6 0.9 3.1 3 0 0 3 3 3 0 Spectrin repeat NOB1_Zn_bind PF08772.11 EGG23131.1 - 5.7 7.2 8.9 25 5.1 1.1 3.0 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like BB_PF PF18063.1 EGG23132.1 - 5.2e-11 42.5 0.1 6.9e-11 42.1 0.1 1.3 1 1 0 1 1 1 1 Beta barrel Pore-forming domain DUF1727 PF08353.10 EGG23132.1 - 0.0032 17.4 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1727) Ig_6 PF18452.1 EGG23132.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 Immunoglobulin domain CLASP_N PF12348.8 EGG23133.1 - 0.072 12.7 0.1 0.072 12.7 0.1 2.2 2 0 0 2 2 2 0 CLASP N terminal Leo1 PF04004.13 EGG23134.1 - 2.5e-42 144.5 0.3 2.5e-42 144.5 0.3 3.6 3 1 0 3 3 3 1 Leo1-like protein SR-25 PF10500.9 EGG23134.1 - 0.0033 17.1 40.4 0.0033 17.1 40.4 3.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Nod1 PF17114.5 EGG23134.1 - 0.023 14.9 0.1 0.051 13.7 0.1 1.6 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 Dynamin_N PF00350.23 EGG23135.1 - 0.00029 20.9 0.0 0.00064 19.8 0.0 1.7 1 0 0 1 1 1 1 Dynamin family F-box-like PF12937.7 EGG23136.1 - 3.4e-07 30.1 0.1 1.1e-06 28.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG23136.1 - 0.0077 16.1 0.2 0.069 13.0 0.2 2.8 1 1 0 1 1 1 1 F-box domain SDA1 PF05285.12 EGG23136.1 - 0.083 12.3 6.0 0.17 11.3 6.0 1.4 1 0 0 1 1 1 0 SDA1 CKAP2_C PF15297.6 EGG23136.1 - 1.4 7.9 12.6 0.032 13.3 1.7 2.2 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Striatin PF08232.12 EGG23136.1 - 6.1 7.4 11.7 6 7.4 2.7 3.3 3 0 0 3 3 3 0 Striatin family THOC2_N PF16134.5 EGG23137.1 - 3.3e-51 174.7 24.1 1.2e-48 166.3 19.9 3.0 1 1 1 2 2 2 2 THO complex subunit 2 N-terminus Tho2 PF11262.8 EGG23138.1 - 1.8e-83 280.2 13.9 1.8e-83 280.2 13.9 6.5 3 1 3 6 6 6 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EGG23138.1 - 1.3e-26 92.4 0.3 6e-26 90.3 0.0 2.4 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Arm PF00514.23 EGG23138.1 - 0.13 12.3 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Rh5 PF18515.1 EGG23139.1 - 0.025 13.9 0.6 0.028 13.7 0.6 1.0 1 0 0 1 1 1 0 Rh5 coiled-coil domain Oxidored-like PF09791.9 EGG23140.1 - 2.5e-12 46.2 0.5 5.5e-12 45.1 0.5 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DNA_pol_phi PF04931.13 EGG23140.1 - 0.0058 14.8 0.2 0.0058 14.8 0.2 2.0 2 0 0 2 2 2 1 DNA polymerase phi DUF5522 PF17653.1 EGG23140.1 - 0.18 11.8 3.1 0.48 10.4 3.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5522) AF-4 PF05110.13 EGG23140.1 - 0.22 9.6 14.3 0.32 9.0 14.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 EGG23140.1 - 0.42 10.2 23.4 0.047 13.3 18.0 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.13 EGG23140.1 - 0.79 10.4 5.5 3.4 8.3 2.8 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sox_N PF12444.8 EGG23140.1 - 1.4 10.1 9.1 0.31 12.2 4.1 2.2 2 0 0 2 2 2 0 Sox developmental protein N terminal rve PF00665.26 EGG23142.1 - 0.0028 17.8 0.0 0.004 17.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain LRV_FeS PF05484.11 EGG23143.1 - 0.0049 16.8 0.3 0.37 10.8 0.1 2.1 2 0 0 2 2 2 2 LRV protein FeS4 cluster Guanylate_kin PF00625.21 EGG23144.1 - 0.0031 17.2 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 Guanylate kinase DDE_Tnp_1_2 PF13586.6 EGG23147.1 - 2.3 8.6 4.5 1.9 8.9 0.2 2.8 3 0 0 3 3 3 0 Transposase DDE domain bZIP_1 PF00170.21 EGG23148.1 - 6.1e-12 45.5 11.7 6.1e-12 45.5 11.7 2.6 3 1 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 EGG23148.1 - 3.2e-08 33.5 11.4 3.2e-08 33.5 11.4 3.3 3 2 1 4 4 4 2 Basic region leucine zipper bZIP_Maf PF03131.17 EGG23148.1 - 0.0051 17.3 7.3 0.0051 17.3 7.3 2.6 3 0 0 3 3 3 1 bZIP Maf transcription factor Cwf_Cwc_15 PF04889.12 EGG23148.1 - 0.057 13.1 24.8 0.08 12.7 24.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 EGG23148.1 - 5.2 5.2 18.2 6 5.0 18.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RhoGAP PF00620.27 EGG23149.1 - 1.3e-33 116.0 0.0 7.6e-33 113.5 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain Carm_PH PF17888.1 EGG23149.1 - 2.2e-08 34.4 0.5 6e-08 32.9 0.5 1.8 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_6 PF13516.6 EGG23149.1 - 0.005 16.8 0.5 0.005 16.8 0.5 9.0 12 0 0 12 12 12 3 Leucine Rich repeat LRR_4 PF12799.7 EGG23149.1 - 0.13 12.7 39.1 1.1 9.8 0.0 7.6 4 2 4 8 8 8 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGG23149.1 - 0.53 11.0 16.0 28 5.8 0.1 8.5 10 1 0 10 10 10 0 Leucine Rich Repeat CAS_C PF12026.8 EGG23150.1 - 0.066 13.3 0.4 0.15 12.1 0.4 1.5 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain vATP-synt_AC39 PF01992.16 EGG23152.1 - 6.8e-114 380.8 5.2 7.7e-114 380.7 5.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TCTP PF00838.17 EGG23153.1 - 1.9e-59 200.7 4.5 2.2e-59 200.5 4.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein tRNA_int_endo PF01974.17 EGG23154.1 - 6.6e-19 67.8 0.0 1.2e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EGG23154.1 - 8.6e-07 28.5 0.4 8.6e-06 25.3 0.4 2.5 1 1 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain VPS28 PF03997.12 EGG23154.1 - 0.12 12.0 3.9 1.2 8.8 0.1 2.8 2 1 1 3 3 3 0 VPS28 protein Reo_P9 PF06043.11 EGG23154.1 - 0.14 11.5 6.2 0.3 10.5 6.2 1.4 1 0 0 1 1 1 0 Reovirus P9-like family E1-E2_ATPase PF00122.20 EGG23155.1 - 7.4e-48 162.5 1.9 7.4e-48 162.5 1.9 3.4 3 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGG23155.1 - 8.5e-17 62.1 0.8 6.4e-16 59.3 0.8 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGG23155.1 - 1.3e-13 50.4 0.0 2.5e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGG23155.1 - 5.6e-05 23.2 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGG23155.1 - 0.0025 17.6 0.1 0.0025 17.6 0.1 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Phage_head_fibr PF11133.8 EGG23155.1 - 0.016 14.6 0.1 0.03 13.7 0.1 1.4 1 0 0 1 1 1 0 Head fiber protein CH PF00307.31 EGG23156.1 - 4.3e-14 52.6 2.7 7.1e-14 51.9 0.1 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGG23156.1 - 0.007 16.2 0.0 0.007 16.2 0.0 2.1 2 0 0 2 2 2 1 CAMSAP CH domain RIFIN PF02009.16 EGG23156.1 - 0.12 12.2 11.3 0.009 15.9 6.2 1.6 2 0 0 2 2 2 0 Rifin MRAP PF15183.6 EGG23156.1 - 0.53 10.3 3.1 1.8 8.5 3.1 1.9 1 1 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DnaB PF00772.21 EGG23157.1 - 0.046 13.8 0.4 7.1 6.8 0.1 2.4 2 0 0 2 2 2 0 DnaB-like helicase N terminal domain Peptidase_M1 PF01433.20 EGG23158.1 - 1.6e-10 40.9 0.0 4.8e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 EGG23158.1 - 0.085 13.3 0.0 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 HEAT repeats PEMT PF04191.13 EGG23159.1 - 6.3e-28 97.3 3.6 6.3e-28 97.3 3.6 1.9 2 1 0 2 2 2 1 Phospholipid methyltransferase XPG_N PF00752.17 EGG23160.1 - 8.1e-29 100.1 0.0 1.5e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGG23160.1 - 2.4e-28 98.3 0.1 6.4e-28 97.0 0.0 1.8 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 EGG23160.1 - 5.6e-05 23.7 0.1 0.00078 20.0 0.0 2.6 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold VPS9 PF02204.18 EGG23162.1 - 2.5e-31 108.0 0.2 8.9e-31 106.2 0.2 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 EGG23162.1 - 3.9e-13 49.8 11.0 3.4e-05 24.3 0.3 5.6 3 1 4 7 7 7 5 Ankyrin repeats (3 copies) DUF5601 PF18151.1 EGG23162.1 - 2.1e-08 34.4 0.0 9.6e-08 32.2 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) Ank_4 PF13637.6 EGG23162.1 - 9.9e-07 29.2 8.3 2.3 8.9 0.1 6.7 4 3 3 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG23162.1 - 1.3e-06 28.5 7.0 2.7 8.4 0.1 8.4 6 3 4 10 10 10 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23162.1 - 9.6e-05 22.5 6.7 30 5.6 0.0 8.6 10 0 0 10 10 10 0 Ankyrin repeat Spore_YhcN_YlaJ PF09580.10 EGG23162.1 - 0.00031 20.8 0.0 0.013 15.6 0.0 3.0 2 2 0 2 2 2 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) SUIM_assoc PF16619.5 EGG23162.1 - 0.0068 16.5 11.8 0.035 14.2 5.8 3.0 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF5049 PF16468.5 EGG23162.1 - 0.032 14.1 0.1 6.7 6.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5049) Ras PF00071.22 EGG23163.1 - 3e-64 215.5 0.3 3.7e-64 215.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG23163.1 - 6.5e-36 123.2 0.3 1.3e-35 122.2 0.3 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG23163.1 - 1.1e-18 67.3 0.2 1.4e-18 66.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGG23163.1 - 7.9e-07 29.1 0.2 0.016 15.1 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGG23163.1 - 1.4e-06 27.8 0.1 1.7e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGG23163.1 - 1.4e-05 24.7 0.4 4.5e-05 23.1 0.2 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG23163.1 - 2e-05 24.7 0.0 4e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGG23163.1 - 4.1e-05 23.1 0.0 5.7e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGG23163.1 - 0.00066 19.2 0.1 0.2 11.2 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA PF00004.29 EGG23163.1 - 0.00073 20.0 0.0 1.1 9.7 0.0 2.3 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) LepB_N PF18640.1 EGG23163.1 - 0.025 14.2 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 LepB N-terminal domain TniB PF05621.11 EGG23163.1 - 0.034 13.5 0.0 0.28 10.6 0.0 2.2 2 1 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 EGG23163.1 - 0.035 13.9 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG23163.1 - 0.048 14.0 0.0 0.098 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EGG23163.1 - 0.049 13.5 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EGG23163.1 - 0.055 13.7 0.0 0.16 12.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain Peptidase_S66 PF02016.15 EGG23163.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain ABC_tran PF00005.27 EGG23163.1 - 0.091 13.3 0.4 0.18 12.3 0.4 1.7 1 1 0 1 1 1 0 ABC transporter SdrD_B PF17210.3 EGG23164.1 - 7.3e-27 93.8 0.5 2.6e-12 47.0 0.0 2.7 2 0 0 2 2 2 2 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG23164.1 - 1e-12 48.1 2.2 3.3e-06 27.3 0.5 2.9 3 0 0 3 3 3 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EGG23164.1 - 9.5e-07 28.7 0.2 0.0014 18.6 0.1 2.6 2 0 0 2 2 2 2 CarboxypepD_reg-like domain SpaA PF17802.1 EGG23164.1 - 0.0016 18.7 0.5 0.042 14.2 0.2 2.5 2 0 0 2 2 2 1 Prealbumin-like fold domain bMG3 PF11974.8 EGG23164.1 - 0.0024 17.8 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 Bacterial alpha-2-macroglobulin MG3 domain MetallophosN PF16371.5 EGG23164.1 - 0.0035 17.6 2.9 7.5 6.9 0.0 4.3 3 1 0 4 4 4 1 N terminal of Calcineurin-like phosphoesterase Dioxygenase_C PF00775.21 EGG23164.1 - 0.12 11.8 0.1 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 Dioxygenase FoP_duplication PF13865.6 EGG23164.1 - 9.3 6.9 14.9 16 6.1 14.9 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ECH_1 PF00378.20 EGG23165.1 - 2.6e-87 292.3 0.3 3.2e-87 292.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGG23165.1 - 7e-42 144.1 1.5 8e-37 127.5 0.3 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EGG23165.1 - 0.0042 17.1 0.1 0.31 11.0 0.0 2.4 2 0 0 2 2 2 1 Peptidase family S49 SDH_sah PF01972.16 EGG23165.1 - 0.068 12.2 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Serine dehydrogenase proteinase BTG PF07742.12 EGG23166.1 - 8.8e-20 70.7 0.0 1.3e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 BTG family ABC_membrane PF00664.23 EGG23167.1 - 1.2e-55 189.1 36.6 6.8e-36 124.3 11.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGG23167.1 - 1.2e-43 148.9 3.0 6.5e-25 88.2 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 EGG23167.1 - 2.8e-09 36.7 3.6 0.00074 19.0 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGG23167.1 - 8.4e-05 22.2 1.5 0.47 10.2 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG23167.1 - 0.00089 19.2 1.0 0.079 12.9 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase DUF815 PF05673.13 EGG23167.1 - 0.0011 18.2 0.1 0.017 14.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 EGG23167.1 - 0.002 18.2 7.3 0.48 10.5 0.3 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EGG23167.1 - 0.027 14.3 2.1 30 4.3 0.0 4.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EGG23167.1 - 0.043 13.3 0.4 8 5.9 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 EGG23167.1 - 0.05 12.6 1.1 2.3 7.1 0.1 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 EGG23167.1 - 0.072 12.7 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGG23167.1 - 0.093 13.1 1.3 18 5.7 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain IstB_IS21 PF01695.17 EGG23167.1 - 0.098 12.4 0.4 21 4.8 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 EGG23167.1 - 0.28 10.9 2.1 25 4.5 0.4 2.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGG23167.1 - 3 8.4 8.2 0.3 11.6 0.1 3.1 3 0 0 3 3 3 0 AAA domain Synaptobrevin PF00957.21 EGG23170.1 - 1.5e-27 95.2 5.6 1.7e-27 95.1 5.6 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF1676 PF07898.13 EGG23170.1 - 0.0074 16.3 0.3 0.0087 16.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) RIFIN PF02009.16 EGG23170.1 - 0.0085 16.0 0.4 0.0091 15.9 0.4 1.0 1 0 0 1 1 1 1 Rifin Ferlin_C PF16165.5 EGG23170.1 - 0.011 15.7 0.3 0.011 15.7 0.3 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Orf78 PF06024.12 EGG23170.1 - 0.026 14.8 2.4 0.026 14.8 2.4 1.7 1 1 1 2 2 2 0 Orf78 (ac78) TraD_N PF12615.8 EGG23170.1 - 0.028 15.2 0.3 0.032 15.0 0.3 1.2 1 0 0 1 1 1 0 F sex factor protein N terminal SET PF00856.28 EGG23171.1 - 8.4e-16 58.8 3.8 5.2e-15 56.2 3.8 2.0 1 1 0 1 1 1 1 SET domain PAP_central PF04928.17 EGG23171.1 - 0.0025 16.8 0.0 0.0046 16.0 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain SMK-1 PF04802.15 EGG23171.1 - 0.033 14.0 0.2 0.091 12.6 0.1 1.7 1 1 1 2 2 2 0 Component of IIS longevity pathway SMK-1 CDC27 PF09507.10 EGG23171.1 - 0.22 10.8 5.1 0.31 10.4 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RNA_pol_3_Rpc31 PF11705.8 EGG23171.1 - 0.71 10.1 11.3 1.2 9.3 11.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DPBB_1 PF03330.18 EGG23173.1 - 0.017 15.4 0.4 0.17 12.2 0.4 2.3 1 1 0 1 1 1 0 Lytic transglycolase EGF_2 PF07974.13 EGG23174.1 - 0.00047 20.5 17.8 0.00047 20.5 17.8 2.3 2 0 0 2 2 2 1 EGF-like domain Epiglycanin_C PF14654.6 EGG23174.1 - 0.11 12.5 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region hEGF PF12661.7 EGG23174.1 - 0.15 12.7 10.6 0.67 10.7 10.6 2.3 1 0 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.27 EGG23174.1 - 1.3 9.4 11.7 3.2 8.1 11.7 1.7 1 0 0 1 1 1 0 EGF-like domain DUF3844 PF12955.7 EGG23174.1 - 2.6 8.2 6.6 0.28 11.3 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) LRR_4 PF12799.7 EGG23174.1 - 7.4 7.2 10.1 11 6.5 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Resolvase PF00239.21 EGG23175.1 - 0.024 14.7 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Resolvase, N terminal domain Ank_2 PF12796.7 EGG23175.1 - 0.063 13.9 0.3 4.3 8.0 0.0 3.7 5 0 0 5 5 5 0 Ankyrin repeats (3 copies) Utp14 PF04615.13 EGG23177.1 - 1.2e-120 404.4 81.8 1.2e-120 404.4 81.8 3.0 1 1 1 2 2 2 1 Utp14 protein NAGidase PF07555.13 EGG23179.1 - 6e-17 61.9 0.1 8.8e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase NAGidase PF07555.13 EGG23180.1 - 2.3e-06 27.2 0.0 2.3e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 beta-N-acetylglucosaminidase Pox_RNA_pol PF03293.14 EGG23180.1 - 0.098 12.4 0.0 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Mo25 PF08569.11 EGG23181.1 - 1.1e-131 439.1 21.0 1.2e-131 439.0 21.0 1.0 1 0 0 1 1 1 1 Mo25-like RRM_1 PF00076.22 EGG23182.1 - 4.3e-14 52.1 0.1 9.8e-11 41.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 EGG23182.1 - 0.00056 19.9 0.2 0.32 11.0 0.0 2.3 2 0 0 2 2 2 2 DbpA RNA binding domain RRM_occluded PF16842.5 EGG23182.1 - 0.097 12.5 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif SBD PF17882.1 EGG23185.1 - 0.0092 15.8 0.3 0.014 15.2 0.3 1.4 1 1 0 1 1 1 1 OAA-family lectin sugar binding domain Methyltransf_11 PF08241.12 EGG23186.1 - 3.9e-25 88.3 0.0 9.2e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG23186.1 - 9e-23 80.8 0.0 1.5e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG23186.1 - 1.5e-22 80.1 0.0 3.4e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG23186.1 - 1.3e-19 70.6 0.0 2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG23186.1 - 1.1e-16 60.9 0.0 2.2e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGG23186.1 - 2.1e-14 53.5 0.1 5.6e-14 52.1 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EGG23186.1 - 8.5e-13 48.9 0.0 1.7e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Polyketide_cyc2 PF10604.9 EGG23186.1 - 1.9e-07 31.4 0.7 4.3e-07 30.3 0.3 1.8 2 0 0 2 2 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_15 PF09445.10 EGG23186.1 - 1.5e-05 24.6 0.0 3.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 EGG23186.1 - 1.6e-05 24.9 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGG23186.1 - 0.00016 21.2 0.0 0.0019 17.7 0.0 2.3 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_8 PF05148.15 EGG23186.1 - 0.00026 20.9 0.0 0.0023 17.8 0.0 2.4 2 1 0 2 2 1 1 Hypothetical methyltransferase DOT1 PF08123.13 EGG23186.1 - 0.00028 20.5 0.0 0.00061 19.4 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.19 EGG23186.1 - 0.00033 20.5 0.0 0.00077 19.3 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EGG23186.1 - 0.00035 20.2 0.0 0.00074 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain COXG PF06240.13 EGG23186.1 - 0.0014 18.4 0.5 0.0027 17.5 0.5 1.5 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) MetW PF07021.12 EGG23186.1 - 0.002 17.8 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW ADH_zinc_N PF00107.26 EGG23186.1 - 0.0033 17.4 0.0 0.0084 16.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UPF0020 PF01170.18 EGG23186.1 - 0.0034 17.1 0.0 0.0087 15.8 0.0 1.8 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 TehB PF03848.14 EGG23186.1 - 0.014 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 EGG23186.1 - 0.015 15.3 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EGG23186.1 - 0.016 14.8 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 zf-RING_2 PF13639.6 EGG23187.1 - 8e-11 42.1 3.0 1.8e-10 41.0 3.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGG23187.1 - 1.4e-09 37.5 3.8 2.9e-09 36.5 3.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EGG23187.1 - 1.8e-07 31.4 3.5 1.8e-07 31.4 3.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGG23187.1 - 2.5e-07 30.4 2.6 5.5e-07 29.3 2.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG23187.1 - 7.5e-06 25.7 3.4 2.1e-05 24.3 3.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGG23187.1 - 8.8e-06 25.2 5.5 1.6e-05 24.4 5.5 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EGG23187.1 - 9.3e-05 22.4 0.8 0.00025 21.0 0.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGG23187.1 - 0.00045 20.1 4.5 0.001 19.0 4.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGG23187.1 - 0.0014 18.6 5.3 0.003 17.5 5.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 EGG23187.1 - 0.014 15.2 1.5 0.014 15.2 1.5 1.9 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 EGG23187.1 - 0.029 14.5 2.3 0.075 13.2 2.3 1.7 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EGG23187.1 - 0.032 14.4 3.7 0.09 13.0 3.7 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.6 EGG23187.1 - 0.083 12.8 1.7 0.19 11.6 1.2 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Peptidase_M78 PF06114.13 EGG23187.1 - 0.1 12.6 2.2 0.23 11.4 2.2 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain zf-C3HC4_5 PF17121.5 EGG23187.1 - 0.27 11.2 3.3 0.59 10.1 3.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EGG23187.1 - 0.29 11.5 2.7 0.71 10.2 2.7 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 EGG23187.1 - 0.36 10.9 2.8 0.25 11.4 0.3 2.0 2 0 0 2 2 1 0 Zinc-finger Prok-RING_4 PF14447.6 EGG23187.1 - 0.48 10.3 5.8 1.3 8.9 5.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Arch_flagellin PF01917.16 EGG23187.1 - 9.5 6.4 8.7 19 5.4 8.7 1.5 1 0 0 1 1 1 0 Archaebacterial flagellin Methyltr_RsmB-F PF01189.17 EGG23188.1 - 1.5e-69 233.6 1.7 2.5e-69 232.9 0.0 2.1 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EGG23188.1 - 3.1e-10 40.4 0.2 2.4e-09 37.5 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EGG23188.1 - 9.5e-05 22.6 0.1 0.0013 18.9 0.0 2.4 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.19 EGG23188.1 - 0.0021 17.8 0.0 0.0056 16.5 0.0 1.7 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 EGG23188.1 - 0.0026 17.6 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 EGG23188.1 - 0.0051 17.5 0.0 0.024 15.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG23188.1 - 0.039 13.3 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family 2-oxoacid_dh PF00198.23 EGG23189.1 - 5.2e-80 268.2 0.1 7.7e-80 267.7 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGG23189.1 - 2.7e-39 132.8 5.2 4.9e-19 67.9 1.0 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 EGG23189.1 - 4e-13 49.5 0.0 1.2e-12 47.9 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain DUF515 PF04415.12 EGG23189.1 - 0.0045 15.4 2.3 0.11 10.8 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF515) Biotin_lipoyl_2 PF13533.6 EGG23189.1 - 0.016 15.0 0.0 6.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like GCV_H PF01597.19 EGG23189.1 - 0.02 14.8 0.2 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Glycine cleavage H-protein PYNP_C PF07831.13 EGG23189.1 - 0.088 12.5 0.2 21 4.8 0.1 2.7 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Ribosomal_60s PF00428.19 EGG23189.1 - 0.34 11.5 31.6 2.5 8.8 5.6 3.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein FGGY_C PF02782.16 EGG23190.1 - 2.8e-40 138.2 1.6 3.7e-40 137.8 0.6 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGG23190.1 - 5.9e-28 98.1 0.2 1.6e-20 73.7 0.0 2.3 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EGG23190.1 - 0.00032 20.3 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family PH PF00169.29 EGG23192.1 - 3.2e-30 104.7 9.7 1e-14 54.9 0.8 4.5 3 1 0 3 3 3 3 PH domain PH_11 PF15413.6 EGG23192.1 - 1.2e-07 32.0 13.5 0.12 12.8 3.9 5.3 3 2 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 EGG23192.1 - 0.00017 21.6 4.1 0.017 15.2 0.7 3.6 3 0 0 3 3 3 1 PH domain PH_8 PF15409.6 EGG23192.1 - 0.00028 21.1 2.6 0.2 11.9 0.3 3.8 3 1 0 3 3 3 2 Pleckstrin homology domain DUF846 PF05832.12 EGG23192.1 - 0.034 14.2 4.6 0.17 11.9 2.2 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) PH_9 PF15410.6 EGG23192.1 - 0.042 14.2 3.0 0.16 12.4 0.9 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain PH_13 PF16652.5 EGG23192.1 - 0.086 12.6 0.3 7 6.4 0.0 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain NIF PF03031.18 EGG23193.1 - 4.7e-53 179.1 0.5 4.7e-53 179.1 0.5 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase SUIM_assoc PF16619.5 EGG23193.1 - 4.4 7.4 14.9 2.8 8.1 5.2 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CBP_BcsS PF17036.5 EGG23194.1 - 0.031 14.2 2.9 0.094 12.6 2.9 1.8 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsS DUF4190 PF13828.6 EGG23194.1 - 0.13 12.1 1.0 0.28 10.9 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) Adeno_E3B PF03376.14 EGG23194.1 - 0.94 9.8 3.1 0.95 9.7 1.2 1.9 2 0 0 2 2 2 0 Adenovirus E3B protein RIP PF00161.19 EGG23195.1 - 0.012 15.2 1.1 0.028 14.0 1.1 1.6 1 0 0 1 1 1 0 Ribosome inactivating protein DUF3175 PF11373.8 EGG23195.1 - 0.2 11.9 0.5 0.52 10.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3175) Mito_carr PF00153.27 EGG23196.1 - 1.1e-68 227.2 1.3 2.5e-23 81.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2971 PF11185.8 EGG23196.1 - 0.78 10.9 0.0 0.78 10.9 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2971) Nucleoside_tran PF01733.18 EGG23198.1 - 4.5e-46 157.6 24.7 4.5e-46 157.6 24.7 1.9 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 EGG23198.1 - 0.0004 19.4 22.0 0.0004 19.4 22.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2383 PF09537.10 EGG23199.1 - 0.0065 16.8 0.1 0.0095 16.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) Ferritin PF00210.24 EGG23199.1 - 0.031 14.2 2.2 0.37 10.7 0.1 2.4 2 1 0 2 2 2 0 Ferritin-like domain Rubrerythrin PF02915.17 EGG23199.1 - 0.11 12.9 1.2 1.2 9.6 1.3 1.9 1 1 0 1 1 1 0 Rubrerythrin Mac PF12464.8 EGG23200.1 - 2.3e-14 53.4 0.0 4.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 EGG23200.1 - 2.6e-10 39.9 6.8 1.8e-07 30.8 2.9 3.3 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EGG23200.1 - 8.4e-10 38.0 13.8 9.5e-10 37.8 3.5 3.3 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Coiled PF05710.12 EGG23201.1 - 0.0029 18.4 6.2 0.0031 18.3 6.2 1.2 1 0 0 1 1 1 1 Coiled coil GATase_6 PF13522.6 EGG23203.1 - 6.4e-19 68.5 0.1 1.4e-18 67.4 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain SIS PF01380.22 EGG23203.1 - 7.6e-15 54.9 0.0 2e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 SIS domain GATase_7 PF13537.6 EGG23203.1 - 2.2e-13 50.2 0.0 6.7e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EGG23203.1 - 0.015 14.2 0.1 0.14 11.0 0.2 2.0 2 0 0 2 2 2 0 Glutamine amidotransferases class-II bact-PGI_C PF10432.9 EGG23203.1 - 0.14 12.2 0.2 2.1 8.4 0.1 2.6 2 1 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain RabGAP-TBC PF00566.18 EGG23204.1 - 1.7e-43 148.8 6.3 3.1e-43 147.9 6.3 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EGG23204.1 - 2.3e-20 72.7 2.8 2.3e-20 72.7 2.8 3.2 2 1 1 3 3 3 2 Rab-binding domain (RBD) LPD39 PF18858.1 EGG23204.1 - 0.14 12.2 0.3 0.26 11.4 0.3 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 ATP-synt_ab PF00006.25 EGG23205.1 - 1.4e-108 361.5 0.0 2.2e-108 360.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EGG23205.1 - 8e-43 145.2 0.1 1.5e-42 144.3 0.1 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EGG23205.1 - 2.1e-15 57.0 1.6 3.7e-15 56.2 0.4 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ubiquitin PF00240.23 EGG23206.1 - 2.9e-28 97.4 0.2 3.2e-28 97.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGG23206.1 - 2.3e-16 59.4 0.2 2.5e-16 59.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGG23206.1 - 5.9e-06 26.7 0.1 1.8e-05 25.1 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGG23206.1 - 0.00014 21.7 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain YIF1 PF03878.15 EGG23207.1 - 7e-79 264.7 5.7 9.7e-79 264.3 5.7 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EGG23207.1 - 2.6e-05 24.0 2.7 4.5e-05 23.2 2.7 1.4 1 0 0 1 1 1 1 Yip1 domain DUF2306 PF10067.9 EGG23207.1 - 0.0083 16.3 3.4 0.013 15.7 3.4 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) Ras PF00071.22 EGG23208.1 - 5.8e-17 61.8 0.0 5.5e-15 55.3 0.0 2.2 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGG23208.1 - 5.5e-15 55.6 0.0 1.2e-13 51.3 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG23208.1 - 8.1e-06 25.4 0.0 0.00036 20.0 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG23208.1 - 0.00042 20.4 0.0 0.00087 19.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG23208.1 - 0.0036 17.2 0.2 0.16 11.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase FMN_red PF03358.15 EGG23209.1 - 1.2e-28 99.8 0.0 1.5e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGG23209.1 - 3.6e-07 30.1 0.0 5.6e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin-like fold EGF_Tenascin PF18720.1 EGG23210.1 - 0.034 14.2 7.5 0.072 13.2 7.5 1.6 1 0 0 1 1 1 0 Tenascin EGF domain Toxin_10 PF05431.11 EGG23210.1 - 0.04 13.4 0.1 0.04 13.4 0.1 2.6 2 0 0 2 2 2 0 Insecticidal Crystal Toxin, P42 EGF_2 PF07974.13 EGG23210.1 - 1.3 9.5 12.6 2.5 8.6 12.6 1.5 1 0 0 1 1 1 0 EGF-like domain Pkinase_Tyr PF07714.17 EGG23211.1 - 3.5e-26 92.0 0.8 3.5e-26 92.0 0.8 2.6 2 1 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 EGG23211.1 - 9.6e-23 80.9 6.3 9.6e-23 80.9 6.3 2.5 2 1 0 2 2 2 1 Protein kinase domain Sel1 PF08238.12 EGG23211.1 - 8.6e-12 45.3 16.7 0.00055 20.5 0.1 7.6 8 0 0 8 8 8 3 Sel1 repeat FTA2 PF13095.6 EGG23211.1 - 2.5e-05 24.0 9.8 0.033 13.8 0.0 4.2 3 1 1 4 4 4 3 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGG23211.1 - 0.0054 15.5 1.0 0.0092 14.8 0.2 1.7 2 0 0 2 2 2 1 Fungal protein kinase TPR_12 PF13424.6 EGG23211.1 - 0.036 14.4 0.1 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat APH PF01636.23 EGG23211.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Topoisom_I_N PF02919.15 EGG23211.1 - 0.3 10.6 6.1 0.89 9.0 6.1 1.8 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment PH PF00169.29 EGG23212.1 - 2e-05 25.0 0.3 2e-05 25.0 0.3 3.0 2 2 0 2 2 2 1 PH domain ZIP4_domain PF18292.1 EGG23212.1 - 0.18 11.7 0.0 0.18 11.7 0.0 3.3 3 0 0 3 3 3 0 Zinc transporter ZIP4 domain KID PF02524.14 EGG23213.1 - 0.24 11.6 2.0 1.1 9.7 0.3 2.6 2 0 0 2 2 2 0 KID repeat DUF4808 PF16066.5 EGG23213.1 - 0.3 11.7 3.7 0.58 10.7 3.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4808) Caldesmon PF02029.15 EGG23214.1 - 0.02 13.7 30.5 0.028 13.2 30.5 1.1 1 0 0 1 1 1 0 Caldesmon Borrelia_P83 PF05262.11 EGG23214.1 - 4.2 5.7 38.2 6.2 5.2 38.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DASH_Spc34 PF08657.10 EGG23215.1 - 0.0079 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Spc34 ATPase-cat_bd PF12156.8 EGG23215.1 - 0.092 13.5 1.1 0.18 12.6 0.2 1.9 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase GGDEF PF00990.21 EGG23216.1 - 1.5e-35 122.3 0.7 2.6e-35 121.6 0.7 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Guanylate_cyc PF00211.20 EGG23216.1 - 0.0074 15.9 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Amino_oxidase PF01593.24 EGG23218.1 - 2.5e-40 139.2 0.0 5.1e-38 131.5 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGG23218.1 - 8.5e-11 41.9 0.0 2.1e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG23218.1 - 3e-07 30.3 0.0 8.1e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG23218.1 - 1.5e-06 27.7 0.0 0.0068 15.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGG23218.1 - 8.4e-06 24.7 0.1 0.0015 17.3 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 EGG23218.1 - 6.4e-05 23.4 0.1 0.39 11.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGG23218.1 - 0.00021 20.5 0.0 0.00033 19.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EGG23218.1 - 0.00025 20.4 0.0 0.00062 19.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EGG23218.1 - 0.00099 18.6 0.0 0.34 10.2 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGG23218.1 - 0.0014 18.0 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EGG23218.1 - 0.0015 17.8 0.0 0.29 10.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGG23218.1 - 0.0081 15.3 0.0 2.6 7.0 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 EGG23218.1 - 0.021 14.8 0.1 6.9 6.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.19 EGG23219.1 - 1.7e-40 139.3 0.1 1.7e-40 139.3 0.1 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGG23219.1 - 8.6e-24 84.7 0.0 4.1e-23 82.5 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGG23219.1 - 4.5e-06 26.0 0.5 7.4e-06 25.3 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGG23219.1 - 5e-06 26.7 0.1 1.2e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGG23219.1 - 4.5e-05 23.2 0.1 0.0058 16.2 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG23219.1 - 0.00019 20.8 0.1 0.0029 16.9 0.0 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGG23219.1 - 0.00028 20.3 0.6 0.00046 19.5 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EGG23219.1 - 0.0076 15.3 0.2 0.012 14.6 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EGG23219.1 - 0.011 14.9 0.2 0.023 13.9 0.2 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EGG23219.1 - 0.013 14.2 2.4 0.018 13.8 0.7 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 EGG23219.1 - 0.16 11.3 2.8 0.32 10.3 2.8 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EGG23219.1 - 0.18 10.8 1.6 0.33 10.0 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF4834 PF16118.5 EGG23219.1 - 0.49 11.4 1.9 4.9 8.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 EGG23220.1 - 7.7e-68 228.7 0.5 1.7e-67 227.5 0.5 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23220.1 - 8.9e-52 175.9 2.4 9.2e-52 175.9 0.2 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG23220.1 - 0.00069 19.0 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGG23220.1 - 0.041 13.8 0.0 2.1 8.2 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Prefoldin_2 PF01920.20 EGG23221.1 - 1.2e-18 67.0 14.9 1.2e-18 67.0 14.9 1.7 1 1 0 1 1 1 1 Prefoldin subunit RhoGEF67_u2 PF16614.5 EGG23221.1 - 0.18 11.9 2.5 0.098 12.7 0.6 1.6 2 0 0 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 Prefoldin_3 PF13758.6 EGG23221.1 - 0.19 11.8 7.2 0.29 11.2 7.2 1.4 1 0 0 1 1 1 0 Prefoldin subunit Sec34 PF04136.15 EGG23221.1 - 0.25 11.2 8.9 0.99 9.3 2.2 2.1 2 0 0 2 2 2 0 Sec34-like family CFAP91 PF14738.6 EGG23221.1 - 0.3 11.1 14.7 1.6 8.7 2.4 2.1 1 1 1 2 2 2 0 Cilia- and flagella-associated protein 91 DUF2203 PF09969.9 EGG23221.1 - 0.72 10.6 8.0 1.8 9.3 8.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) COG2 PF06148.11 EGG23221.1 - 1.8 8.6 9.1 5.1 7.2 3.7 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin PF02996.17 EGG23221.1 - 2.3 8.2 17.7 2.2e+02 1.8 17.9 2.7 1 1 0 1 1 1 0 Prefoldin subunit Spore_III_AB PF09548.10 EGG23221.1 - 2.3 8.3 8.0 14 5.7 7.9 2.0 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Aida_N PF08910.10 EGG23221.1 - 3.1 8.2 8.8 4.7 7.7 2.1 2.1 1 1 1 2 2 2 0 Aida N-terminus MCU PF04678.13 EGG23221.1 - 3.9 7.5 10.1 63 3.6 10.1 2.1 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Peptidase_M18 PF02127.15 EGG23222.1 - 1.5e-159 531.5 0.0 2e-159 531.0 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EGG23222.1 - 5.9e-05 22.2 0.0 0.0013 17.8 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase RdRP PF05183.12 EGG23223.1 - 1.4e-132 443.4 0.1 4.2e-132 441.8 0.1 1.9 2 0 0 2 2 2 1 RNA dependent RNA polymerase Helicase_C PF00271.31 EGG23223.1 - 3.3e-22 78.9 2.4 2.8e-20 72.7 0.2 4.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG23223.1 - 5e-14 52.7 0.1 1.9e-13 50.8 0.1 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG23223.1 - 1.1e-09 38.3 0.0 4.7e-09 36.3 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase RIG-I_C-RD PF11648.8 EGG23223.1 - 0.002 18.3 0.1 0.0071 16.6 0.1 1.9 1 0 0 1 1 1 1 C-terminal domain of RIG-I DUF1464 PF07318.12 EGG23223.1 - 0.1 11.8 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Peptidase_A8 PF01252.18 EGG23223.1 - 0.16 12.2 0.1 0.4 10.9 0.1 1.6 1 0 0 1 1 1 0 Signal peptidase (SPase) II Ras PF00071.22 EGG23224.1 - 7.9e-54 181.6 0.0 1.1e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG23224.1 - 4.2e-19 68.9 0.0 8.9e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG23224.1 - 8e-08 31.9 0.3 1.2e-07 31.3 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG23224.1 - 0.00016 21.3 0.9 0.00045 19.8 0.4 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain OTCace_N PF02729.21 EGG23224.1 - 0.0016 18.5 0.1 0.0025 17.8 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain G-alpha PF00503.20 EGG23224.1 - 0.0025 17.0 12.2 0.11 11.6 0.4 3.3 1 1 1 2 2 2 2 G-protein alpha subunit ATP_bind_1 PF03029.17 EGG23224.1 - 0.033 14.0 1.3 0.052 13.3 0.2 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein baeRF_family3 PF18845.1 EGG23224.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 Peptidase_C1 PF00112.23 EGG23225.1 - 0.0057 16.8 4.6 0.21 11.6 0.1 2.2 1 1 0 2 2 2 2 Papain family cysteine protease DUF1201 PF06716.11 EGG23225.1 - 3.5 7.7 6.3 3.9 7.6 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) RNA_pol_3_Rpc31 PF11705.8 EGG23226.1 - 0.014 15.6 9.9 0.014 15.6 9.9 2.9 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 ANAPC15 PF15243.6 EGG23226.1 - 0.017 15.5 7.1 0.017 15.5 7.1 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 TLP-20 PF06088.11 EGG23226.1 - 0.091 12.6 13.3 0.12 12.2 2.1 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF727 PF05303.12 EGG23226.1 - 0.56 10.3 4.2 2 8.5 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF727) RNase_H2_suC PF08615.11 EGG23226.1 - 0.61 10.3 4.4 2.6 8.2 1.1 2.7 3 0 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) WASH_WAHD PF11945.8 EGG23227.1 - 1.3e-54 185.7 0.1 2e-54 185.1 0.1 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex WH2 PF02205.20 EGG23227.1 - 1.7e-05 24.4 0.2 4e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 WH2 motif Rep_fac_C PF08542.11 EGG23228.1 - 2.1e-17 63.3 1.0 7.9e-17 61.5 0.0 2.4 3 0 0 3 3 2 1 Replication factor C C-terminal domain AAA PF00004.29 EGG23228.1 - 3.4e-17 63.1 0.0 6.2e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGG23228.1 - 7.4e-12 45.3 0.1 2.5e-08 33.8 0.0 2.9 2 1 1 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EGG23228.1 - 9.4e-11 42.0 0.7 3.3e-08 33.7 0.0 3.2 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 EGG23228.1 - 7.4e-06 26.4 0.0 1.6e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG23228.1 - 1.8e-05 25.0 0.1 0.012 15.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EGG23228.1 - 4e-05 23.4 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EGG23228.1 - 5.8e-05 22.7 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 EGG23228.1 - 9.9e-05 22.4 0.0 0.0004 20.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EGG23228.1 - 0.00012 21.4 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 EGG23228.1 - 0.00014 21.7 0.0 0.0017 18.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EGG23228.1 - 0.00016 21.6 0.2 0.0039 17.0 0.0 2.6 2 2 1 3 3 3 1 AAA domain AAA_assoc_2 PF16193.5 EGG23228.1 - 0.00021 21.6 0.0 0.00054 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_3 PF07726.11 EGG23228.1 - 0.00023 21.0 0.0 0.0005 19.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGG23228.1 - 0.00035 20.4 0.0 0.00095 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGG23228.1 - 0.00056 19.9 0.0 0.0021 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGG23228.1 - 0.00098 19.7 0.0 0.004 17.7 0.0 2.1 2 1 1 3 3 2 1 AAA domain TniB PF05621.11 EGG23228.1 - 0.0013 18.2 0.0 0.81 9.1 0.0 2.4 1 1 0 2 2 2 2 Bacterial TniB protein DEAD PF00270.29 EGG23228.1 - 0.0021 17.9 0.1 0.0091 15.8 0.1 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ATPase_2 PF01637.18 EGG23228.1 - 0.0038 17.2 0.1 0.024 14.5 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGG23228.1 - 0.005 17.2 0.0 0.08 13.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain ResIII PF04851.15 EGG23228.1 - 0.0061 16.6 0.0 0.29 11.1 0.0 2.5 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 EGG23228.1 - 0.0082 15.9 0.0 0.13 12.0 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 EGG23228.1 - 0.021 14.5 0.0 0.047 13.4 0.0 1.6 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase MCM PF00493.23 EGG23228.1 - 0.027 13.6 0.0 0.056 12.5 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_23 PF13476.6 EGG23228.1 - 0.027 15.0 0.7 0.077 13.5 0.6 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGG23228.1 - 0.04 14.3 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 EGG23228.1 - 0.048 13.9 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGG23228.1 - 0.06 12.7 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 EGG23228.1 - 0.099 12.3 0.1 0.32 10.6 0.0 1.9 3 0 0 3 3 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 EGG23228.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EGG23228.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain VAPB_antitox PF02697.14 EGG23228.1 - 0.49 11.2 3.6 0.66 10.8 0.5 2.9 3 0 0 3 3 2 0 Putative antitoxin Glyco_transf_22 PF03901.17 EGG23229.1 - 4.5e-84 283.1 34.8 5.4e-84 282.8 34.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 EGG23229.1 - 0.0044 17.2 16.2 0.0044 17.2 16.2 2.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TRIQK PF15168.6 EGG23229.1 - 0.039 13.8 0.0 0.3 11.0 0.0 2.6 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family RRM_1 PF00076.22 EGG23231.1 - 1.2e-28 98.7 0.0 2.4e-09 36.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP13 PF12921.7 EGG23232.1 - 0.035 13.9 0.1 0.14 12.0 0.1 2.0 1 0 0 1 1 1 0 Mitochondrial ATPase expression RPN13_C PF16550.5 EGG23232.1 - 0.077 13.2 2.0 0.18 12.0 2.0 1.6 1 0 0 1 1 1 0 UCH-binding domain FB_lectin PF07367.11 EGG23232.1 - 0.66 9.9 4.4 0.16 11.9 0.7 1.9 2 0 0 2 2 2 0 Fungal fruit body lectin AJAP1_PANP_C PF15298.6 EGG23232.1 - 1.3 9.2 9.8 18 5.5 6.7 2.4 2 0 0 2 2 2 0 AJAP1/PANP C-terminus SapB_1 PF05184.15 EGG23233.1 - 2.3e-31 107.4 18.1 4.5e-11 42.5 2.9 4.3 4 0 0 4 4 4 3 Saposin-like type B, region 1 SapB_2 PF03489.17 EGG23233.1 - 1.7e-27 95.2 27.3 2.2e-12 46.8 1.7 4.8 6 0 0 6 6 6 3 Saposin-like type B, region 2 DUF4806 PF16064.5 EGG23233.1 - 0.19 12.1 0.2 1.9 8.8 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) Apt1 PF10351.9 EGG23233.1 - 0.94 8.3 9.4 1.3 7.8 9.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EGG23233.1 - 1.9 6.9 8.2 2.3 6.7 8.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF4451 PF14616.6 EGG23233.1 - 2.1 8.5 5.8 12 6.2 2.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4451) SPX PF03105.19 EGG23233.1 - 4.5 7.1 8.8 5.7 6.7 8.8 1.1 1 0 0 1 1 1 0 SPX domain ROK PF00480.20 EGG23234.1 - 1.9e-48 165.5 0.0 2.6e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 ROK family TIG PF01833.24 EGG23234.1 - 2.3e-07 30.8 3.9 6.7e-07 29.3 3.9 1.8 1 0 0 1 1 1 1 IPT/TIG domain TBCC PF07986.12 EGG23235.1 - 5.9e-25 87.3 7.0 5.9e-25 87.3 7.0 2.5 1 1 1 2 2 2 1 Tubulin binding cofactor C CAP_C PF08603.11 EGG23235.1 - 0.039 13.6 6.8 0.022 14.3 1.6 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal Ribosomal_L19e PF01280.20 EGG23236.1 - 2.3e-61 206.1 6.8 2.3e-61 206.1 6.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e DUF382 PF04037.13 EGG23236.1 - 0.21 11.7 4.1 0.35 11.0 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF382) TFIIE_alpha PF02002.17 EGG23236.1 - 0.39 10.6 5.1 0.65 9.9 5.1 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit OmdA PF13376.6 EGG23236.1 - 0.72 9.9 8.5 0.46 10.5 2.1 2.9 1 1 1 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated WRW PF10206.9 EGG23237.1 - 0.0085 16.4 0.1 0.0094 16.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f F1F0-ATPsyn_F PF10791.9 EGG23237.1 - 0.014 15.9 0.0 0.016 15.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Kinesin PF00225.23 EGG23238.1 - 1.6e-102 342.9 5.2 1.6e-102 342.9 5.2 3.5 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EGG23238.1 - 5.9e-23 81.4 0.2 5.9e-23 81.4 0.2 4.0 4 0 0 4 4 4 1 Microtubule binding DnaJ PF00226.31 EGG23238.1 - 1.7e-05 24.8 0.2 6.3e-05 23.0 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain DUF3223 PF11523.8 EGG23238.1 - 0.0053 17.6 4.8 0.49 11.3 0.1 4.0 3 1 0 3 3 3 2 Protein of unknown function (DUF3223) Surp PF01805.20 EGG23239.1 - 2e-15 56.5 0.2 2e-15 56.5 0.2 2.4 2 0 0 2 2 2 1 Surp module RRM_1 PF00076.22 EGG23239.1 - 1.5e-12 47.1 0.0 3.9e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 EGG23239.1 - 0.017 15.9 0.2 0.017 15.9 0.2 2.4 2 0 0 2 2 2 0 RNA polymerase II-binding domain. SNAPc_SNAP43 PF09808.9 EGG23240.1 - 5.2e-28 98.3 2.7 5.2e-28 98.3 2.7 1.9 2 1 1 3 3 3 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 PTS_2-RNA PF01885.16 EGG23241.1 - 3.2e-24 86.0 0.0 3.7e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family NAGLU_N PF12971.7 EGG23241.1 - 0.03 14.1 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain BAR PF03114.18 EGG23242.1 - 2.3e-17 63.5 12.1 3.6e-17 62.8 12.1 1.3 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 EGG23242.1 - 9.9e-15 54.1 0.0 1.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGG23242.1 - 1.1e-13 50.6 0.0 1.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG23242.1 - 1.1e-08 34.6 0.0 2.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.13 EGG23242.1 - 0.009 15.6 12.8 0.018 14.6 12.8 1.5 1 1 0 1 1 1 1 Arfaptin-like domain Sec34 PF04136.15 EGG23242.1 - 0.014 15.3 2.7 0.032 14.1 1.0 2.3 1 1 0 2 2 2 0 Sec34-like family KASH_CCD PF14662.6 EGG23242.1 - 0.12 12.2 7.9 0.14 12.0 7.2 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 EGG23242.1 - 3.3 7.9 8.7 4 7.6 0.9 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prenyltrans PF00432.21 EGG23243.1 - 1.2e-62 207.3 6.8 5.2e-14 51.7 0.2 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EGG23243.1 - 3e-06 26.5 0.7 0.00041 19.5 0.0 2.7 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGG23243.1 - 8.7e-05 21.8 0.0 0.17 10.9 0.0 3.7 1 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain AgI_II_C2 PF17998.1 EGG23243.1 - 0.12 12.7 0.5 0.19 12.0 0.5 1.3 1 0 0 1 1 1 0 Cell surface antigen I/II C2 terminal domain Aa_trans PF01490.18 EGG23244.1 - 1.4e-54 185.4 33.3 1.6e-54 185.2 33.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGG23244.1 - 7.4e-07 28.5 23.3 4.1e-06 26.1 23.3 2.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Glycophorin_A PF01102.18 EGG23244.1 - 0.17 12.1 3.2 43 4.4 0.1 3.9 4 0 0 4 4 4 0 Glycophorin A S1 PF00575.23 EGG23245.1 - 5.7e-22 77.9 8.0 1.6e-05 25.2 0.1 7.1 6 1 0 6 6 6 3 S1 RNA binding domain Caldesmon PF02029.15 EGG23245.1 - 0.017 13.9 34.9 0.0077 15.0 11.0 2.1 2 0 0 2 2 2 0 Caldesmon Folate_carrier PF01770.18 EGG23245.1 - 2.4 6.8 3.6 0.68 8.6 0.3 1.8 2 0 0 2 2 2 0 Reduced folate carrier Glyco_transf_8 PF01501.20 EGG23246.1 - 2.9e-07 30.3 1.0 2.9e-07 30.3 1.0 2.3 1 1 1 2 2 2 1 Glycosyl transferase family 8 HemX PF04375.14 EGG23246.1 - 6.3e-05 22.4 6.3 0.00011 21.7 6.3 1.3 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Nucleotid_trans PF03407.16 EGG23246.1 - 7e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Comm PF15957.5 EGG23246.1 - 0.0075 16.6 0.1 0.038 14.3 0.0 2.2 2 0 0 2 2 2 1 Commissureless SID-1_RNA_chan PF13965.6 EGG23246.1 - 0.0098 14.4 4.7 0.013 14.0 4.7 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DUF3139 PF11337.8 EGG23246.1 - 0.016 15.8 0.1 0.044 14.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) DUF4834 PF16118.5 EGG23246.1 - 0.023 15.7 2.9 0.05 14.6 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2828 PF11443.8 EGG23246.1 - 0.028 12.5 5.7 0.045 11.8 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) IFRD PF05004.13 EGG23246.1 - 0.16 11.1 7.4 0.28 10.3 7.4 1.4 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Connexin PF00029.19 EGG23246.1 - 0.16 11.7 3.1 0.3 10.8 3.1 1.4 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 EGG23246.1 - 0.25 11.4 1.6 0.48 10.5 1.4 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 EGG23246.1 - 0.27 10.1 1.7 0.37 9.7 1.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Vfa1 PF08432.10 EGG23246.1 - 1.4 9.2 16.0 2.6 8.4 16.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 EGG23246.1 - 2.8 6.1 14.7 3.9 5.6 14.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Endonuc_Holl PF10107.9 EGG23246.1 - 3.3 7.6 9.9 0.46 10.3 5.3 1.9 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase CSRNP_N PF16019.5 EGG23246.1 - 6.2 6.7 10.4 10 6.0 10.4 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus EIIBC-GUT_N PF03612.14 EGG23246.1 - 6.7 6.4 7.6 11 5.7 7.6 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pantoate_transf PF02548.15 EGG23247.1 - 4.7e-111 370.3 2.2 9.4e-111 369.3 2.2 1.5 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.11 EGG23247.1 - 5.1e-30 104.2 0.0 1.5e-29 102.7 0.0 1.9 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EGG23247.1 - 4e-29 101.2 0.4 1.2e-28 99.7 0.1 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 EGG23247.1 - 2.1e-05 24.5 0.5 8.6e-05 22.6 0.5 2.1 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 EGG23247.1 - 0.00011 21.9 0.7 0.00033 20.3 0.0 2.1 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PEP_mutase PF13714.6 EGG23247.1 - 0.00024 20.6 0.6 0.00068 19.2 0.1 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Shikimate_DH PF01488.20 EGG23247.1 - 0.0036 17.4 0.6 0.073 13.1 0.1 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EGG23247.1 - 0.0036 17.2 0.8 0.07 13.0 0.0 3.2 4 0 0 4 4 4 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGG23247.1 - 0.0056 16.9 0.1 0.017 15.3 0.1 1.9 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Asp_Glu_race PF01177.22 EGG23247.1 - 0.0098 15.8 0.1 0.12 12.2 0.0 2.6 3 0 0 3 3 3 1 Asp/Glu/Hydantoin racemase F420_oxidored PF03807.17 EGG23247.1 - 0.032 14.8 0.2 0.096 13.3 0.2 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent YtzH PF14165.6 EGG23247.1 - 0.21 12.0 5.1 0.14 12.5 1.7 2.6 3 0 0 3 3 3 0 YtzH-like protein UQ_con PF00179.26 EGG23248.1 - 4e-19 68.6 0.9 5.7e-19 68.2 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme SR-25 PF10500.9 EGG23248.1 - 0.004 16.8 17.1 0.004 16.8 17.1 1.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF1129 PF06570.11 EGG23248.1 - 0.0076 15.8 1.9 0.012 15.1 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) DUF2207 PF09972.9 EGG23248.1 - 0.032 13.0 2.8 0.041 12.7 2.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RWD PF05773.22 EGG23248.1 - 0.048 14.0 1.0 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 RWD domain Orf78 PF06024.12 EGG23248.1 - 0.057 13.7 1.6 0.099 12.9 1.5 1.5 1 1 0 1 1 1 0 Orf78 (ac78) ATP-synt_F6 PF05511.11 EGG23248.1 - 0.082 13.3 1.2 0.18 12.2 0.6 1.8 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 DUF2115 PF09888.9 EGG23248.1 - 0.088 13.3 3.4 0.13 12.7 3.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) PspB PF06667.12 EGG23248.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Phage shock protein B HCO3_cotransp PF00955.21 EGG23248.1 - 0.1 11.4 4.1 0.13 11.1 4.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF4199 PF13858.6 EGG23248.1 - 1.8 8.9 6.3 4.5 7.6 5.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) ABC_tran PF00005.27 EGG23249.1 - 6.6e-27 94.7 0.0 1.2e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGG23249.1 - 1.4e-05 25.0 1.3 0.0052 16.6 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGG23249.1 - 0.0011 19.4 0.1 0.0018 18.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGG23249.1 - 0.0048 16.8 0.1 0.011 15.7 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase Rad17 PF03215.15 EGG23249.1 - 0.0099 15.8 0.0 0.022 14.7 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain SbcCD_C PF13558.6 EGG23249.1 - 0.015 15.5 0.3 0.31 11.3 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGG23249.1 - 0.12 12.1 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EGG23249.1 - 0.18 11.7 1.0 5.2 7.0 0.1 2.3 2 0 0 2 2 2 0 NACHT domain Aa_trans PF01490.18 EGG23250.1 - 2.6e-52 177.9 30.7 3.1e-52 177.7 30.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SpoIID PF08486.10 EGG23251.1 - 0.0094 16.5 0.0 0.011 16.2 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein SET PF00856.28 EGG23252.1 - 2e-15 57.6 0.3 1.1e-14 55.2 0.0 2.3 2 1 0 2 2 2 1 SET domain EF-hand_1 PF00036.32 EGG23252.1 - 2.7e-08 32.8 0.1 0.023 14.2 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EGG23252.1 - 6.2e-08 33.0 0.0 7.4e-05 23.1 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGG23252.1 - 6.6e-06 25.6 0.0 2.7 8.1 0.0 4.1 3 0 0 3 3 3 2 EF-hand domain TPR_1 PF00515.28 EGG23252.1 - 2.3e-05 24.0 2.4 0.0065 16.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat EF-hand_8 PF13833.6 EGG23252.1 - 0.00028 20.6 0.0 0.051 13.4 0.0 3.6 3 1 1 4 4 4 1 EF-hand domain pair TPR_2 PF07719.17 EGG23252.1 - 0.00043 20.2 3.0 3.7 7.9 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat EF-hand_5 PF13202.6 EGG23252.1 - 0.0005 19.4 0.2 2 8.1 0.0 3.4 4 0 0 4 4 4 2 EF hand zf-MYND PF01753.18 EGG23252.1 - 0.0022 18.0 14.0 0.006 16.7 13.7 1.9 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EGG23252.1 - 0.033 14.3 3.3 0.13 12.4 3.3 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 TPR_16 PF13432.6 EGG23252.1 - 0.074 13.7 0.0 1.5 9.5 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGG23252.1 - 0.15 12.4 7.3 0.23 11.7 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG23252.1 - 0.59 10.5 4.2 0.45 10.8 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EGG23252.1 - 3.9 7.6 6.9 17 5.6 0.1 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Aa_trans PF01490.18 EGG23253.1 - 1.6e-38 132.5 36.5 1.6e-29 102.8 22.5 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein DUF1129 PF06570.11 EGG23253.1 - 0.23 10.9 0.0 0.23 10.9 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1129) Pkinase PF00069.25 EGG23254.1 - 7.1e-59 199.3 0.0 1.7e-58 198.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23254.1 - 2.3e-37 128.7 0.0 3.7e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG23254.1 - 2.4e-11 43.5 0.0 4.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGG23254.1 - 0.0021 17.2 0.7 0.64 9.0 0.0 3.0 3 0 0 3 3 3 2 Seadornavirus VP7 APH PF01636.23 EGG23254.1 - 0.01 15.7 0.0 0.27 11.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family SporV_AA PF12164.8 EGG23254.1 - 0.021 15.2 0.9 0.085 13.2 0.9 2.1 1 0 0 1 1 1 0 Stage V sporulation protein AA Kdo PF06293.14 EGG23254.1 - 0.053 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGG23254.1 - 0.08 11.7 0.1 0.19 10.5 0.1 1.5 1 0 0 1 1 1 0 Fungal protein kinase T4_baseplate PF12322.8 EGG23254.1 - 1.5 8.2 5.6 0.44 10.0 0.7 2.4 3 0 0 3 3 3 0 T4 bacteriophage base plate protein Methyltransf_11 PF08241.12 EGG23255.1 - 3.6e-14 53.2 0.0 6.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG23255.1 - 1.8e-10 41.4 0.0 3.8e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG23255.1 - 1.2e-06 28.4 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG23255.1 - 6.5e-05 23.6 0.0 0.00013 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGG23255.1 - 0.0042 17.0 0.0 0.0087 15.9 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 EGG23255.1 - 0.011 15.1 0.0 0.072 12.4 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGG23255.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 EGG23255.1 - 0.016 14.8 0.0 0.05 13.2 0.0 1.8 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 EGG23255.1 - 0.024 14.5 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SOG2 PF10428.9 EGG23256.1 - 0.31 10.2 11.6 0.34 10.0 11.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 EGG23256.1 - 2.3 6.8 7.4 3.2 6.3 7.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ENTH PF01417.20 EGG23257.1 - 9.8e-16 57.9 10.1 1.6e-09 37.8 0.6 2.8 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.16 EGG23257.1 - 9.4e-05 21.5 0.8 0.0089 15.1 0.0 2.5 2 0 0 2 2 2 2 ANTH domain SR-25 PF10500.9 EGG23258.1 - 0.00093 18.9 35.9 0.044 13.4 14.5 3.4 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein DUF1492 PF07374.11 EGG23258.1 - 0.011 15.9 0.1 0.039 14.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Spectrin PF00435.21 EGG23258.1 - 0.074 13.6 0.2 0.074 13.6 0.2 2.1 2 0 0 2 2 2 0 Spectrin repeat T3SS_NleG PF06416.12 EGG23259.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Effector protein NleG Senescence_reg PF04520.13 EGG23260.1 - 1.1 10.0 6.2 1.7 9.4 6.2 1.2 1 0 0 1 1 1 0 Senescence regulator Auxin_canalis PF05703.11 EGG23260.1 - 2.4 8.1 6.2 3.5 7.5 6.2 1.2 1 0 0 1 1 1 0 Auxin canalisation Bromodomain PF00439.25 EGG23261.1 - 2.9e-06 27.2 2.2 3.3e-06 27.1 0.1 2.1 2 0 0 2 2 2 1 Bromodomain FHA PF00498.26 EGG23261.1 - 0.046 14.1 0.1 0.14 12.5 0.1 1.9 1 0 0 1 1 1 0 FHA domain Coilin_N PF15862.5 EGG23261.1 - 0.092 12.6 0.0 0.092 12.6 0.0 8.4 4 3 3 7 7 7 0 Coilin N-terminus FtsJ PF01728.19 EGG23262.1 - 1.3e-30 106.9 0.0 4e-30 105.2 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.23 EGG23262.1 - 1.3e-14 53.8 0.5 2.7e-14 52.8 0.5 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGG23262.1 - 2.8e-08 33.7 0.2 2.8e-08 33.7 0.2 2.4 2 0 0 2 2 2 1 G-patch domain G_path_suppress PF15991.5 EGG23262.1 - 1 9.5 29.3 2.1 8.4 19.9 2.3 2 0 0 2 2 2 0 G-protein pathway suppressor TFIIA PF03153.13 EGG23262.1 - 5.4 6.9 36.0 0.091 12.7 23.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4 PF00097.25 EGG23263.1 - 1.4e-05 24.9 14.9 1.4e-05 24.9 14.9 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG23263.1 - 2.4e-05 24.2 11.5 2.4e-05 24.2 11.5 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 EGG23263.1 - 7.1e-05 22.6 3.3 7.1e-05 22.6 3.3 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 EGG23263.1 - 0.00012 21.8 14.0 0.00012 21.8 14.0 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG23263.1 - 0.00051 19.9 13.5 0.00051 19.9 13.5 2.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG23263.1 - 0.006 16.9 13.1 0.006 16.9 13.1 2.8 2 1 1 3 3 3 1 Ring finger domain cwf21 PF08312.12 EGG23263.1 - 1.2 9.4 4.0 3.4 7.9 4.0 1.7 1 1 0 1 1 1 0 cwf21 domain PHD PF00628.29 EGG23264.1 - 4.6e-23 80.9 53.2 5e-09 35.9 13.7 4.8 3 1 1 4 4 4 3 PHD-finger HMG_box PF00505.19 EGG23264.1 - 3.1e-18 66.0 0.1 3.1e-18 66.0 0.1 2.7 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGG23264.1 - 1e-12 48.4 0.0 1e-12 48.4 0.0 3.1 3 0 0 3 3 3 1 HMG-box domain C1_1 PF00130.22 EGG23264.1 - 0.016 15.1 6.7 0.016 15.1 6.7 6.3 3 2 3 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Requiem_N PF14051.6 EGG23264.1 - 0.87 9.8 0.0 0.87 9.8 0.0 3.5 3 0 0 3 3 3 0 N-terminal domain of DPF2/REQ. Exonuc_VII_L PF02601.15 EGG23264.1 - 3.5 7.1 39.4 0.49 9.9 4.3 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Pro_CA PF00484.19 EGG23265.1 - 6.9e-50 169.4 0.1 1.1e-49 168.8 0.1 1.3 1 0 0 1 1 1 1 Carbonic anhydrase DUF3919 PF13057.6 EGG23265.1 - 0.0048 16.5 3.3 0.0056 16.3 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3919) SPX PF03105.19 EGG23266.1 - 1.4 8.8 0.0 1.4 8.8 0.0 4.5 2 1 0 3 3 3 0 SPX domain Med19 PF10278.9 EGG23267.1 - 0.008 16.1 0.1 0.008 16.1 0.1 3.5 3 1 0 4 4 4 1 Mediator of RNA pol II transcription subunit 19 RabGAP-TBC PF00566.18 EGG23268.1 - 1.5e-39 135.9 9.2 1.5e-39 135.9 9.2 2.8 3 1 0 3 3 3 1 Rab-GTPase-TBC domain DUF5401 PF17380.2 EGG23268.1 - 0.73 7.8 6.5 1.2 7.1 6.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Rad51 PF08423.11 EGG23269.1 - 5.9e-09 35.5 6.0 0.0001 21.6 0.1 3.6 4 1 0 4 4 4 2 Rad51 ATPase PF06745.13 EGG23269.1 - 2.5e-05 23.7 3.3 0.0007 19.0 0.1 3.2 3 0 0 3 3 3 1 KaiC RecA PF00154.21 EGG23269.1 - 0.00024 20.7 0.0 0.00066 19.2 0.0 1.7 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EGG23269.1 - 0.022 14.3 0.1 0.2 11.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGG23269.1 - 0.087 13.3 1.6 0.16 12.5 0.1 2.1 2 0 0 2 2 2 0 ABC transporter Oxidored_q6 PF01058.22 EGG23270.1 - 2e-22 79.4 0.2 2.6e-22 79.1 0.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Tmemb_14 PF03647.13 EGG23270.1 - 0.14 13.0 0.0 0.22 12.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane proteins 14C NuA4 PF09340.10 EGG23271.1 - 1e-23 83.0 0.7 2.7e-23 81.6 0.7 1.7 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Isy1 PF06246.12 EGG23271.1 - 0.0071 15.9 0.9 0.0071 15.9 0.9 2.3 1 1 1 2 2 2 1 Isy1-like splicing family BSP_II PF05432.11 EGG23271.1 - 0.016 14.9 16.0 0.016 14.9 16.0 1.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FTHFS PF01268.19 EGG23271.1 - 0.061 11.5 0.6 0.082 11.1 0.6 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Fzo_mitofusin PF04799.13 EGG23271.1 - 0.36 10.4 2.3 0.38 10.3 1.3 1.7 1 1 0 1 1 1 0 fzo-like conserved region DUF4407 PF14362.6 EGG23271.1 - 0.58 9.4 4.1 0.71 9.2 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pox_RNA_Pol_19 PF05320.12 EGG23271.1 - 7.9 6.4 13.1 0.56 10.2 7.0 2.0 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit TetR_C_24 PF17932.1 EGG23272.1 - 0.21 11.9 0.5 0.4 11.0 0.5 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Methyltransf_12 PF08242.12 EGG23272.1 - 2 9.2 9.3 3.5 8.4 1.6 3.2 2 0 0 2 2 2 0 Methyltransferase domain Acyltransferase PF01553.21 EGG23273.1 - 5.8e-05 22.7 0.0 9.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TraX PF05857.11 EGG23273.1 - 0.1 12.7 5.8 0.16 12.0 5.8 1.2 1 0 0 1 1 1 0 TraX protein PIG-P PF08510.12 EGG23273.1 - 4.9 7.1 11.4 3.9 7.4 3.2 2.3 2 0 0 2 2 2 0 PIG-P Centro_C10orf90 PF17730.1 EGG23274.1 - 0.13 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Centrosomal C10orf90 Myb_DNA-binding PF00249.31 EGG23275.1 - 2.6e-11 43.5 0.3 4.4e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SUIM_assoc PF16619.5 EGG23275.1 - 0.002 18.1 5.3 3.6e+02 1.3 0.0 3.2 2 2 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Myb_DNA-bind_7 PF15963.5 EGG23275.1 - 0.027 14.3 0.6 0.027 14.3 0.6 2.1 2 0 0 2 2 2 0 Myb DNA-binding like LIN52 PF10044.9 EGG23275.1 - 7 7.4 7.0 38 5.1 1.2 3.5 3 0 0 3 3 3 0 Retinal tissue protein ANAPC5 PF12862.7 EGG23276.1 - 0.0021 18.1 0.6 0.0077 16.3 0.6 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 WYL_3 PF18488.1 EGG23276.1 - 0.034 14.5 0.1 0.18 12.2 0.0 2.4 2 0 0 2 2 2 0 WYL domain TPR_7 PF13176.6 EGG23276.1 - 0.074 13.1 0.5 8.2 6.7 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG23276.1 - 0.086 13.7 0.0 39 5.4 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG23276.1 - 0.11 12.8 1.4 1.7 9.0 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat GAGA_bind PF06217.12 EGG23276.1 - 1 9.6 18.4 2.4 8.3 18.4 1.7 1 0 0 1 1 1 0 GAGA binding protein-like family SDA1 PF05285.12 EGG23276.1 - 1.7 8.0 47.2 1.3 8.4 42.1 2.3 2 0 0 2 2 2 0 SDA1 NPAT_C PF15712.5 EGG23276.1 - 7.4 5.1 22.4 11 4.5 22.4 1.2 1 0 0 1 1 1 0 NPAT C terminus TPR_8 PF13181.6 EGG23276.1 - 7.6 7.0 7.2 33 5.0 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat MMR1 PF08505.10 EGG23276.1 - 9.6 6.4 25.5 0.36 11.1 18.9 2.0 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein AAA PF00004.29 EGG23277.1 - 0.00014 22.3 0.0 0.0017 18.8 0.0 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGG23277.1 - 0.032 14.5 0.0 0.087 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain LPMO_10 PF03067.15 EGG23278.1 - 7e-29 101.9 0.8 8.1e-29 101.7 0.8 1.0 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading COX15-CtaA PF02628.15 EGG23279.1 - 0.012 14.8 0.0 0.012 14.7 0.0 1.0 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Herpes_VP19C PF03327.14 EGG23279.1 - 0.075 12.5 0.1 0.075 12.5 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus capsid shell protein VP19C tRNA_Me_trans PF03054.16 EGG23279.1 - 0.12 11.2 0.0 0.13 11.1 0.0 1.0 1 0 0 1 1 1 0 tRNA methyl transferase HEAT PF02985.22 EGG23280.1 - 2.4e-15 55.3 0.8 0.23 11.8 0.1 7.0 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 EGG23280.1 - 6.4e-14 52.1 0.0 6.4e-05 23.3 0.0 4.5 3 1 1 4 4 4 2 HEAT repeats RTP1_C1 PF10363.9 EGG23280.1 - 0.0013 18.9 2.7 2.7 8.2 0.5 4.4 2 1 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGG23280.1 - 0.018 15.5 0.2 29 5.3 0.0 4.2 5 0 0 5 5 5 0 HEAT-like repeat Cohesin_HEAT PF12765.7 EGG23280.1 - 0.026 14.8 0.5 9.7 6.6 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.7 EGG23280.1 - 0.14 12.8 11.9 17 6.1 0.1 5.4 6 1 1 7 7 7 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGG23280.1 - 0.19 11.7 27.3 0.13 12.3 1.0 5.8 4 2 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Androgen_recep PF02166.16 EGG23280.1 - 4.9 5.9 8.8 8.2 5.1 8.8 1.2 1 0 0 1 1 1 0 Androgen receptor Pex14_N PF04695.13 EGG23280.1 - 6.3 7.4 16.8 6 7.5 3.5 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RRP7 PF12923.7 EGG23281.1 - 2.7e-18 66.2 9.5 2.7e-18 66.2 9.5 4.3 2 1 1 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Adeno_PIX PF03955.14 EGG23281.1 - 0.15 12.3 4.1 0.43 10.8 4.1 1.8 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Chorion_2 PF03964.15 EGG23281.1 - 0.35 11.7 4.5 1.3 9.8 4.5 2.0 1 0 0 1 1 1 0 Chorion family 2 FNIP PF05725.12 EGG23282.1 - 1.1e-46 156.7 36.7 5.5e-09 36.1 1.0 9.9 4 2 6 11 11 11 10 FNIP Repeat F-box PF00646.33 EGG23282.1 - 0.00037 20.3 1.1 0.00037 20.3 1.1 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGG23282.1 - 0.0029 17.5 0.4 0.0089 15.9 0.4 1.9 1 0 0 1 1 1 1 F-box-like VKG_Carbox PF05090.14 EGG23283.1 - 1.8e-06 27.1 16.1 5.8e-06 25.4 16.1 1.7 1 1 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase Ank_2 PF12796.7 EGG23284.1 - 5.9e-17 62.0 1.4 5.9e-08 33.2 0.7 3.7 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG23284.1 - 2.5e-13 50.3 0.7 0.00058 20.4 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG23284.1 - 5e-13 49.0 0.4 3.6e-05 24.0 0.0 4.1 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23284.1 - 1.4e-08 34.3 0.2 0.013 15.9 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EGG23284.1 - 3.8e-07 30.3 0.2 0.008 16.6 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat GAGA_bind PF06217.12 EGG23285.1 - 1 9.6 12.6 1.3 9.2 12.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.17 EGG23285.1 - 6.6 5.4 10.8 8 5.1 10.8 1.3 1 0 0 1 1 1 0 Presenilin COPI_assoc PF08507.10 EGG23286.1 - 4.5e-11 42.9 17.0 6.3e-11 42.4 17.0 1.1 1 0 0 1 1 1 1 COPI associated protein DUF2721 PF11026.8 EGG23286.1 - 0.098 12.5 0.3 0.098 12.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF202 PF02656.15 EGG23286.1 - 0.22 12.0 0.2 0.22 12.0 0.2 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF202) TMEM223 PF14640.6 EGG23286.1 - 0.33 11.1 2.0 21 5.2 0.0 2.5 1 1 1 2 2 2 0 Transmembrane protein 223 FBPase PF00316.20 EGG23287.1 - 1.9e-62 210.1 0.0 2.7e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain YqaH PF17448.2 EGG23287.1 - 0.005 17.1 0.0 0.0093 16.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized YqaH-like CLU PF13236.6 EGG23288.1 - 6e-60 202.8 0.0 1.4e-59 201.6 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria UQ_con PF00179.26 EGG23288.1 - 4.4e-27 94.5 0.0 1.5e-26 92.8 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme eIF3_p135 PF12807.7 EGG23288.1 - 1.7e-11 44.5 0.2 1.7e-11 44.5 0.2 5.5 5 1 0 5 5 5 1 Translation initiation factor eIF3 subunit 135 zf_CCCH_4 PF18345.1 EGG23288.1 - 0.00065 19.7 4.4 0.0019 18.2 4.4 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGG23288.1 - 0.00086 19.0 0.7 0.0018 18.0 0.7 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger LRR_1 PF00560.33 EGG23288.1 - 0.39 11.4 25.0 2.5 9.0 0.3 8.6 8 1 0 8 8 8 0 Leucine Rich Repeat SRP19 PF01922.17 EGG23289.1 - 5.3e-27 94.6 0.8 6e-27 94.4 0.1 1.5 2 0 0 2 2 2 1 SRP19 protein SR-25 PF10500.9 EGG23290.1 - 0.58 9.7 16.1 0.33 10.5 10.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CH PF00307.31 EGG23291.1 - 2.4e-13 50.2 0.2 5.8e-13 49.0 0.2 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain FPP PF05911.11 EGG23291.1 - 0.097 10.9 1.3 0.1 10.8 1.3 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil SR-25 PF10500.9 EGG23292.1 - 3.9e-23 82.3 71.6 3.9e-23 82.3 71.6 2.4 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Peptidase_C1 PF00112.23 EGG23293.1 - 1.1e-68 231.6 6.4 1.1e-68 231.6 6.4 1.8 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG23293.1 - 6.1e-11 42.6 10.7 1.4e-10 41.4 10.7 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) CDKN3 PF05706.12 EGG23295.1 - 3.4e-06 26.8 0.0 5.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.20 EGG23295.1 - 1.8e-05 24.6 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG23295.1 - 0.0094 15.5 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DUF2281 PF10047.9 EGG23295.1 - 0.05 14.3 0.1 5.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) Y_phosphatase3 PF13350.6 EGG23295.1 - 0.053 13.5 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGG23295.1 - 0.059 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family NUDIX PF00293.28 EGG23296.1 - 6.1e-18 65.1 0.0 1.4e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain DUF5011 PF16403.5 EGG23296.1 - 0.019 15.1 1.3 0.17 12.0 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5011) Cation_efflux PF01545.21 EGG23297.1 - 1.8e-28 99.7 10.7 2.3e-28 99.3 10.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGG23297.1 - 8.1e-13 48.3 0.0 2e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF5100 PF17029.5 EGG23297.1 - 0.025 14.4 0.2 0.39 10.6 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5100) MIG-14_Wnt-bd PF06664.12 EGG23297.1 - 0.039 13.2 6.7 0.058 12.6 6.7 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Shisa PF13908.6 EGG23297.1 - 0.071 13.3 0.4 3.6 7.8 0.2 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF5356 PF17309.2 EGG23297.1 - 0.37 10.8 2.8 0.65 10.0 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5356) DUF1700 PF08006.11 EGG23297.1 - 1.4 8.5 5.2 21 4.6 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) SdrD_B PF17210.3 EGG23298.1 - 1.3e-36 125.2 0.5 1.7e-08 34.6 0.0 4.4 4 0 0 4 4 4 4 SdrD B-like domain CarboxypepD_reg PF13620.6 EGG23298.1 - 3.8e-06 27.1 2.9 1.3 9.4 0.0 5.3 5 1 1 6 6 6 3 Carboxypeptidase regulatory-like domain LRR_6 PF13516.6 EGG23299.1 - 2.4e-42 139.4 68.7 4.7e-05 23.1 0.6 17.3 18 0 0 18 18 18 12 Leucine Rich repeat LRR_4 PF12799.7 EGG23299.1 - 4.1e-12 46.1 27.6 0.25 11.8 0.1 11.0 7 2 3 11 11 11 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG23299.1 - 7.4e-05 22.4 48.9 2.1 8.2 1.5 11.9 6 3 6 12 12 12 7 Leucine rich repeat LRR_1 PF00560.33 EGG23299.1 - 0.00011 22.2 24.8 1.2 10.0 0.0 12.1 13 1 0 13 13 13 1 Leucine Rich Repeat LRR_2 PF07723.13 EGG23299.1 - 0.0084 16.7 0.3 54 4.7 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich Repeat TPT PF03151.16 EGG23300.1 - 1.3e-06 28.0 9.7 1.3e-05 24.7 9.6 2.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 EGG23300.1 - 2.3e-05 23.7 1.3 2.3e-05 23.7 1.3 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.20 EGG23300.1 - 0.0057 16.8 25.7 0.25 11.5 13.4 3.3 2 2 0 2 2 2 2 EamA-like transporter family DUF3446 PF11928.8 EGG23300.1 - 0.0086 16.4 9.2 0.059 13.7 6.9 3.1 2 0 0 2 2 2 1 Early growth response N-terminal domain Lig_chan PF00060.26 EGG23300.1 - 1.5 8.7 6.5 2.1 8.1 0.2 3.2 4 0 0 4 4 4 0 Ligand-gated ion channel Slu7 PF11708.8 EGG23301.1 - 7.8e-87 291.4 14.1 7.8e-87 291.4 14.1 4.0 3 1 1 4 4 4 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 EGG23301.1 - 0.077 13.1 1.9 0.17 12.0 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGG23301.1 - 1.6 8.5 6.2 0.37 10.6 2.6 1.8 2 0 0 2 2 2 0 Zinc knuckle Hid1 PF12722.7 EGG23301.1 - 2.5 6.1 15.5 4.5 5.3 15.5 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Beta-lactamase PF00144.24 EGG23302.1 - 3.8e-51 174.3 0.0 6e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase zinc_ribbon_16 PF17034.5 EGG23303.1 - 1.6e-21 76.8 19.8 3.9e-21 75.5 19.8 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family WD40 PF00400.32 EGG23303.1 - 1.7e-05 25.5 9.1 0.04 14.8 0.1 6.0 5 0 0 5 5 5 2 WD domain, G-beta repeat DEAD PF00270.29 EGG23304.1 - 2.4e-08 34.0 0.0 9.8e-06 25.4 0.1 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase GREB1 PF15782.5 EGG23304.1 - 0.00013 19.3 0.5 0.29 8.2 0.0 3.0 3 0 0 3 3 3 3 Gene regulated by oestrogen in breast cancer ResIII PF04851.15 EGG23304.1 - 0.012 15.6 2.7 0.039 14.0 1.2 2.6 2 2 1 3 3 3 0 Type III restriction enzyme, res subunit Uma2 PF05685.12 EGG23305.1 - 0.00052 19.6 0.0 0.00073 19.1 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease Metallophos PF00149.28 EGG23306.1 - 2.4e-30 106.6 2.6 4.5e-30 105.7 2.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EGG23306.1 - 6.5e-27 93.7 1.1 1.6e-26 92.4 1.1 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.17 EGG23306.1 - 2.6e-14 52.1 2.2 1.8e-05 24.5 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGG23306.1 - 7.7e-12 44.5 4.1 0.00043 20.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG23306.1 - 2.8e-08 33.3 3.9 0.0016 18.1 0.1 3.3 3 1 1 4 4 4 2 TPR repeat TPR_8 PF13181.6 EGG23306.1 - 9.7e-06 25.4 3.4 0.013 15.7 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG23306.1 - 0.0001 22.7 0.2 0.00059 20.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG23306.1 - 0.00011 22.8 0.0 0.0036 18.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG23306.1 - 0.00017 22.0 0.4 0.0012 19.3 0.1 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG23306.1 - 0.0018 18.9 0.5 0.02 15.6 0.2 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG23306.1 - 0.036 14.4 0.1 1.3 9.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGG23306.1 - 0.073 13.5 2.5 0.83 10.2 0.4 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Kelch_4 PF13418.6 EGG23306.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Galactose oxidase, central domain Myc_N PF01056.18 EGG23307.1 - 0.011 15.6 15.7 0.1 12.5 1.3 2.5 3 0 0 3 3 3 0 Myc amino-terminal region Ribosomal_60s PF00428.19 EGG23307.1 - 0.02 15.5 2.3 0.02 15.5 2.3 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein BUD22 PF09073.10 EGG23307.1 - 0.093 12.1 25.5 0.21 10.9 3.8 2.2 2 0 0 2 2 2 0 BUD22 zf-RRN7 PF11781.8 EGG23307.1 - 0.11 12.2 0.3 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 SR-25 PF10500.9 EGG23307.1 - 2.6 7.6 29.0 0.073 12.7 6.2 2.6 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF5308 PF17233.2 EGG23307.1 - 9.4 6.4 8.3 5 7.3 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5308) DUF3638 PF12340.8 EGG23308.1 - 3.1e-62 209.9 0.1 7.3e-62 208.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EGG23308.1 - 1.6e-14 53.0 0.0 3.8e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DEAD PF00270.29 EGG23308.1 - 0.0035 17.1 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3987 PF13148.6 EGG23308.1 - 0.17 10.8 0.3 0.41 9.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) zf-ANAPC11 PF12861.7 EGG23309.1 - 3.1e-34 116.9 18.3 3.5e-34 116.7 18.3 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGG23309.1 - 1.9e-22 79.3 20.6 2.7e-22 78.8 20.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGG23309.1 - 2e-06 28.0 22.5 4.1e-05 23.8 22.5 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG23309.1 - 0.0025 17.6 16.9 0.0025 17.6 16.9 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG23309.1 - 0.0046 17.0 9.5 0.015 15.3 9.8 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG23309.1 - 0.0072 16.2 21.7 0.049 13.5 21.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG23309.1 - 0.078 12.9 20.5 1.1 9.3 21.1 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.8 EGG23309.1 - 0.13 12.1 8.8 0.24 11.3 8.8 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Med25_VWA PF11265.8 EGG23310.1 - 1.9e-18 67.1 0.0 5.6e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A SNAP PF14938.6 EGG23311.1 - 6.9e-11 42.1 6.3 2.3e-10 40.4 6.3 1.8 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EGG23311.1 - 4e-08 33.4 0.3 0.00014 22.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG23311.1 - 1.7e-07 30.8 2.2 0.00047 19.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG23311.1 - 3e-07 30.1 0.2 0.0012 18.8 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG23311.1 - 0.0001 22.2 0.3 0.0001 22.2 0.3 3.6 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.9 EGG23311.1 - 0.0014 18.4 6.0 0.058 13.1 1.5 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_7 PF13176.6 EGG23311.1 - 0.028 14.4 0.2 3.2 8.0 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGG23311.1 - 0.11 12.4 0.1 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGG23311.1 - 0.53 10.0 7.9 1.7 8.4 0.1 4.1 5 0 0 5 5 5 0 TPR repeat Citrate_synt PF00285.21 EGG23312.1 - 1.7e-105 353.1 0.0 2e-105 352.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Glyoxalase_4 PF13669.6 EGG23313.1 - 1.1e-18 67.5 0.0 1.3e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 EGG23313.1 - 4.6e-10 39.8 0.0 5e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGG23313.1 - 7.7e-06 26.1 0.0 9.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain MFS_1 PF07690.16 EGG23314.1 - 1e-42 146.4 46.2 1.9e-35 122.4 22.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGG23314.1 - 1.2 7.4 18.9 0.046 12.0 2.9 3.0 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Putative_PNPOx PF01243.20 EGG23317.1 - 3.5e-24 84.8 0.0 6.7e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 EGG23317.1 - 2e-18 66.2 0.0 1e-17 63.9 0.0 2.2 2 1 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyrid_ox_like PF16242.5 EGG23317.1 - 0.011 15.3 0.3 0.054 13.1 0.0 2.1 2 1 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase like DUF3245 PF11595.8 EGG23317.1 - 0.79 10.2 7.4 5.8 7.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Rad51 PF08423.11 EGG23318.1 - 1.1e-38 132.9 0.0 1.5e-34 119.4 0.0 2.1 1 1 1 2 2 2 2 Rad51 ATPase PF06745.13 EGG23318.1 - 3.9e-08 32.9 0.0 1.1e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 EGG23318.1 - 1.5e-07 31.2 0.0 2.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGG23318.1 - 0.00092 19.5 0.5 0.95 9.7 0.2 2.3 2 0 0 2 2 2 2 AAA domain RecA PF00154.21 EGG23318.1 - 0.012 15.1 0.1 2.6 7.4 0.1 2.2 2 0 0 2 2 2 0 recA bacterial DNA recombination protein NACHT PF05729.12 EGG23318.1 - 0.11 12.5 0.4 0.74 9.7 0.0 2.3 3 0 0 3 3 3 0 NACHT domain Mob1_phocein PF03637.17 EGG23319.1 - 7.1e-82 273.5 0.1 8.5e-82 273.2 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family Anillin_N PF16018.5 EGG23320.1 - 0.57 10.8 4.6 0.19 12.4 0.9 2.2 2 0 0 2 2 2 0 Anillin N-terminus FANCI_S4 PF14678.6 EGG23321.1 - 0.02 14.0 0.0 0.021 14.0 0.0 1.0 1 0 0 1 1 1 0 FANCI solenoid 4 NIF PF03031.18 EGG23322.1 - 4.8e-52 175.9 2.0 4.8e-52 175.9 2.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase LMF1 PF06762.14 EGG23323.1 - 2.7e-73 247.6 22.6 3.1e-41 141.9 0.8 2.7 2 1 1 3 3 3 2 Lipase maturation factor RhoGAP PF00620.27 EGG23324.1 - 1.5e-45 154.7 0.1 3.3e-45 153.6 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain IPK PF03770.16 EGG23324.1 - 1.1e-43 149.4 0.2 1.8e-43 148.7 0.2 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pinin_SDK_N PF04697.13 EGG23324.1 - 0.19 12.4 0.8 0.67 10.6 0.3 2.2 1 1 1 2 2 2 0 pinin/SDK conserved region TIMELESS PF04821.14 EGG23324.1 - 0.21 10.8 0.6 0.39 9.9 0.6 1.3 1 0 0 1 1 1 0 Timeless protein M-factor PF03855.13 EGG23324.1 - 7.5 6.8 11.4 30 4.9 11.4 2.1 1 0 0 1 1 1 0 M-factor Cpn60_TCP1 PF00118.24 EGG23325.1 - 2.1e-162 541.2 7.8 2.6e-162 540.9 7.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family 4HBT PF03061.22 EGG23326.1 - 3.3e-10 40.2 0.0 4.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EGG23326.1 - 0.021 15.1 0.0 0.027 14.8 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Imm64 PF15600.6 EGG23326.1 - 0.068 12.8 0.8 0.11 12.1 0.6 1.4 1 1 0 1 1 1 0 Immunity protein 64 PHD PF00628.29 EGG23328.1 - 2.7e-09 36.8 33.7 9.1e-09 35.1 8.8 3.1 3 0 0 3 3 3 2 PHD-finger PHD_2 PF13831.6 EGG23328.1 - 0.00019 20.9 5.7 0.00019 20.9 5.7 3.1 3 0 0 3 3 3 1 PHD-finger Dicty_REP PF05086.12 EGG23329.1 - 0.11 10.5 1.1 0.13 10.2 1.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3847 PF12958.7 EGG23330.1 - 0.066 13.3 0.3 0.15 12.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) TPR_1 PF00515.28 EGG23331.1 - 4.9e-25 86.3 25.5 6.7e-05 22.5 0.2 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGG23331.1 - 5.9e-24 82.2 19.1 9e-06 25.4 0.1 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 EGG23331.1 - 9.7e-17 61.0 18.0 6.5e-07 29.5 3.2 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG23331.1 - 6.4e-14 52.3 8.5 0.0015 19.2 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG23331.1 - 1.4e-12 47.9 17.2 1.9e-05 25.1 0.2 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG23331.1 - 1.1e-10 40.8 23.9 0.47 10.8 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGG23331.1 - 5.3e-09 36.1 6.3 0.12 13.2 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG23331.1 - 1.4e-07 31.0 9.6 0.13 12.3 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG23331.1 - 2.2e-06 27.3 20.0 0.0052 16.4 0.5 4.5 4 0 0 4 4 4 2 TPR repeat TPR_10 PF13374.6 EGG23331.1 - 2.5e-06 27.2 11.0 0.32 10.9 2.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG23331.1 - 6.1e-05 23.2 19.7 0.062 13.5 0.4 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 EGG23331.1 - 0.00046 20.3 1.4 0.05 13.7 0.0 3.4 2 1 0 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 EGG23331.1 - 0.00073 20.0 21.8 0.002 18.6 0.4 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG23331.1 - 0.0011 19.2 11.5 0.0099 16.2 0.3 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG23331.1 - 0.0014 18.7 8.5 0.075 13.1 0.1 4.9 3 1 3 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EGG23331.1 - 0.0067 16.5 21.7 0.81 9.8 0.5 6.4 5 1 1 6 6 6 2 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 EGG23331.1 - 0.012 15.1 9.5 1.1 8.7 0.0 5.2 5 1 0 5 5 5 0 SHNi-TPR BTAD PF03704.17 EGG23331.1 - 0.018 15.5 3.7 3.5 8.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Phasin_2 PF09361.10 EGG23331.1 - 0.02 15.1 0.4 0.02 15.1 0.4 2.6 3 0 0 3 3 3 0 Phasin protein TPR_9 PF13371.6 EGG23331.1 - 0.15 12.2 0.3 2.6 8.3 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat PTS_IIA PF02255.16 EGG23331.1 - 0.23 11.5 4.3 0.15 12.1 0.2 2.8 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Alkyl_sulf_dimr PF14863.6 EGG23331.1 - 0.25 11.8 0.0 0.25 11.8 0.0 2.9 3 1 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_20 PF14561.6 EGG23331.1 - 0.26 11.6 4.9 20 5.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SPO22 PF08631.10 EGG23331.1 - 0.38 10.2 9.2 0.8 9.1 0.1 3.5 2 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like DUF1330 PF07045.11 EGG23331.1 - 0.46 10.9 4.9 7 7.1 1.8 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF1330) Ribosomal_S13_N PF08069.12 EGG23332.1 - 1.3e-29 101.9 0.2 3.1e-29 100.8 0.2 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EGG23332.1 - 1.2e-10 41.5 0.2 1.8e-10 40.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 YflT PF11181.8 EGG23332.1 - 0.022 15.2 0.0 0.033 14.7 0.0 1.2 1 0 0 1 1 1 0 Heat induced stress protein YflT Proteasome PF00227.26 EGG23333.1 - 7.9e-62 208.1 0.0 9.7e-62 207.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGG23333.1 - 3.1e-13 49.1 0.3 6e-13 48.2 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PIP5K PF01504.18 EGG23334.1 - 2.5e-72 243.4 2.8 3.9e-72 242.8 2.8 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Dicty_CAR PF05462.11 EGG23334.1 - 5.8e-08 32.2 0.1 8.8e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 EGG23334.1 - 5e-06 26.5 0.3 2.6e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DNA_pol_A_exo1 PF01612.20 EGG23336.1 - 6.6e-13 48.7 0.0 1.3e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease ABC_membrane PF00664.23 EGG23337.1 - 7.8e-69 232.4 2.6 1e-68 231.9 2.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region STALD PF18185.1 EGG23337.1 - 0.038 13.3 0.1 0.067 12.5 0.1 1.4 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family DUF3937 PF13073.6 EGG23337.1 - 0.18 12.0 1.2 0.35 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) SRP-alpha_N PF04086.13 EGG23337.1 - 0.6 10.0 2.8 1 9.3 2.8 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ABC_tran PF00005.27 EGG23339.1 - 1.9e-13 51.1 0.0 2.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGG23339.1 - 4.9e-07 29.4 0.0 5.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EGG23339.1 - 3.9e-06 25.9 0.0 7.2e-06 25.1 0.0 1.4 1 1 1 2 2 2 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 EGG23339.1 - 9.4e-05 22.6 0.2 0.0034 17.6 0.2 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Caleosin PF05042.13 EGG23340.1 - 0.11 12.4 0.9 0.2 11.6 0.9 1.4 1 0 0 1 1 1 0 Caleosin related protein TALPID3 PF15324.6 EGG23340.1 - 0.83 7.3 4.6 0.99 7.0 4.6 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Tetraspanin PF00335.20 EGG23341.1 - 0.37 10.5 12.5 1.3 8.6 12.5 2.2 1 1 1 2 2 2 0 Tetraspanin family VWA_3 PF13768.6 EGG23342.1 - 8e-23 81.1 0.0 1.6e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain MIF4G PF02854.19 EGG23342.1 - 2e-21 76.6 3.6 6e-21 75.1 3.6 1.8 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 EGG23342.1 - 1.1e-18 67.3 0.5 3.1e-18 65.8 0.5 1.9 1 0 0 1 1 1 1 MA3 domain VWA_2 PF13519.6 EGG23342.1 - 8.8e-13 48.8 0.0 3.2e-12 47.0 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EGG23342.1 - 1.3e-11 45.1 0.0 3.5e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 EGG23342.1 - 5.2e-10 39.5 1.9 1.1e-09 38.5 1.9 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain FANCI_S2 PF14676.6 EGG23342.1 - 0.011 16.0 0.4 1.3 9.3 0.2 2.5 2 0 0 2 2 2 0 FANCI solenoid 2 Pkinase PF00069.25 EGG23344.1 - 2.7e-38 131.8 2.5 4.5e-25 88.5 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23344.1 - 2.6e-26 92.5 0.6 7.1e-16 58.3 0.1 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG23344.1 - 0.00098 18.0 2.2 0.00098 18.0 2.2 2.6 1 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGG23344.1 - 0.058 12.7 0.0 9 5.5 0.0 2.3 2 0 0 2 2 2 0 Kinase-like SNF2_N PF00176.23 EGG23345.1 - 3.7e-54 183.8 0.0 7.5e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG23345.1 - 1.1e-15 57.9 0.0 2.4e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG23345.1 - 1.6e-07 31.5 0.0 1.4e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGG23345.1 - 2.8e-06 27.2 0.0 4.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4718 PF15842.5 EGG23346.1 - 0.41 10.4 2.7 1.1 9.0 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Pex14_N PF04695.13 EGG23346.1 - 3.6 8.2 13.7 0.9 10.2 4.6 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PA14 PF07691.12 EGG23347.1 - 2.6e-12 46.8 0.2 4.9e-12 45.9 0.2 1.5 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 EGG23347.1 - 0.041 14.3 0.5 0.041 14.3 0.5 2.5 3 0 0 3 3 3 0 GLEYA domain PI31_Prot_N PF11566.8 EGG23348.1 - 7.6e-23 81.1 0.2 1.2e-22 80.4 0.2 1.3 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EGG23348.1 - 1e-11 45.8 9.3 1e-11 45.8 9.3 2.5 2 0 0 2 2 2 1 PI31 proteasome regulator PIH1_CS PF18201.1 EGG23349.1 - 9.6e-11 42.0 1.1 1.9e-10 41.1 1.1 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain PIH1 PF08190.12 EGG23349.1 - 5.7e-08 32.4 1.5 4.9e-07 29.4 0.1 2.6 2 1 1 3 3 3 1 PIH1 N-terminal domain DUF3439 PF11921.8 EGG23349.1 - 0.0065 16.4 2.7 0.012 15.5 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGG23349.1 - 4.5 5.4 7.8 6.3 4.9 7.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TIG PF01833.24 EGG23350.1 - 9.9e-05 22.3 14.1 0.79 9.8 0.6 4.4 3 0 0 3 3 3 3 IPT/TIG domain TIG PF01833.24 EGG23351.1 - 2.7e-18 65.8 53.8 0.00011 22.2 0.4 8.3 7 1 1 8 8 8 6 IPT/TIG domain EGF_2 PF07974.13 EGG23351.1 - 0.024 15.0 14.0 0.07 13.5 14.0 1.8 1 0 0 1 1 1 0 EGF-like domain VSG_B PF13206.6 EGG23351.1 - 0.044 13.1 0.1 0.064 12.5 0.1 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain EGF PF00008.27 EGG23351.1 - 0.32 11.4 10.6 1.1 9.7 10.6 2.0 1 0 0 1 1 1 0 EGF-like domain Response_reg PF00072.24 EGG23352.1 - 3.7e-33 114.0 1.5 2.4e-26 92.1 1.0 3.5 4 0 0 4 4 4 2 Response regulator receiver domain HATPase_c PF02518.26 EGG23352.1 - 1.7e-26 92.9 0.0 1.2e-25 90.2 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGG23352.1 - 2.4e-16 59.5 0.4 2.4e-16 59.5 0.4 2.4 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EGG23352.1 - 3.1e-08 33.8 0.1 9.9e-07 29.0 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EGG23352.1 - 3.5e-08 33.5 0.0 8.8e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EGG23352.1 - 1.2e-05 25.5 0.0 3.4e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 EGG23352.1 - 0.058 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1462 PF07315.11 EGG23352.1 - 0.065 13.5 0.1 0.29 11.4 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) DUF1084 PF06454.11 EGG23353.1 - 1.3e-06 28.0 24.1 2.7e-06 27.0 24.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) HATPase_c PF02518.26 EGG23355.1 - 1.8e-27 96.1 0.2 5e-27 94.6 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGG23355.1 - 8.1e-21 74.3 0.0 1.7e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGG23355.1 - 5e-15 55.3 0.1 1.3e-14 54.0 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 EGG23355.1 - 0.00018 21.8 0.0 0.00061 20.1 0.0 1.9 2 0 0 2 2 2 1 GAF domain PAS_9 PF13426.7 EGG23355.1 - 0.0024 18.1 0.1 0.0087 16.3 0.1 2.1 1 0 0 1 1 1 1 PAS domain PPL5 PF18168.1 EGG23355.1 - 0.038 13.3 6.4 0.072 12.4 6.4 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Nrap_D5 PF17406.2 EGG23356.1 - 2e-32 112.2 2.1 8.5e-32 110.1 0.6 2.6 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 EGG23356.1 - 7e-32 110.7 0.0 1.9e-31 109.3 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 EGG23356.1 - 2.1e-27 96.1 13.7 2e-25 89.6 0.5 3.8 3 1 0 3 3 3 2 Nrap protein domain 1 Nrap_D4 PF17405.2 EGG23356.1 - 7.7e-24 84.2 0.2 2.1e-23 82.8 0.2 1.7 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 EGG23356.1 - 3.6e-23 82.0 0.6 2.2e-22 79.5 0.1 2.6 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 EGG23356.1 - 2.5e-12 47.2 5.2 1.6e-11 44.6 0.3 2.7 2 0 0 2 2 2 1 Nrap protein domain 6 Apt1 PF10351.9 EGG23358.1 - 8.8 5.1 30.9 0.31 9.8 5.4 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain DTW PF03942.15 EGG23359.1 - 7.1e-40 136.8 0.6 1.7e-39 135.6 0.6 1.7 1 0 0 1 1 1 1 DTW domain ASD2 PF08687.11 EGG23359.1 - 0.31 10.6 13.1 0.19 11.2 8.4 2.2 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Gly_radical PF01228.21 EGG23359.1 - 6.3 7.4 10.0 1.4 9.5 2.8 3.1 3 1 0 3 3 3 0 Glycine radical Hexapep PF00132.24 EGG23360.1 - 4.6e-08 32.5 16.1 0.0002 20.9 0.7 4.3 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EGG23360.1 - 0.015 14.3 0.3 0.018 14.0 0.3 1.3 1 0 0 1 1 1 0 L-fucokinase DUF4954 PF16314.5 EGG23360.1 - 0.12 10.5 0.4 0.15 10.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EGG23360.1 - 0.6 9.9 9.6 0.35 10.7 1.2 3.5 3 1 2 5 5 5 0 Hexapeptide repeat of succinyl-transferase LRR_6 PF13516.6 EGG23361.1 - 1.9e-06 27.5 9.1 1.9 8.7 0.0 6.9 7 0 0 7 7 7 4 Leucine Rich repeat SpoU_sub_bind PF08032.12 EGG23361.1 - 0.59 10.4 2.7 35 4.8 0.5 3.8 3 1 1 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding 5_3_exonuc PF01367.20 EGG23361.1 - 0.62 10.7 2.5 2.8 8.6 0.1 2.9 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold F5_F8_type_C PF00754.25 EGG23362.1 - 7.2e-23 81.1 1.4 7.2e-23 81.1 1.4 1.6 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.10 EGG23362.1 - 7.8e-18 64.4 3.0 7.8e-18 64.4 3.0 2.2 3 0 0 3 3 3 1 H-type lectin domain Peptidase_M20 PF01546.28 EGG23363.1 - 4.2e-35 121.3 0.0 6e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGG23363.1 - 1.4e-17 63.5 0.4 4.3e-17 62.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain DUF349 PF03993.12 EGG23363.1 - 0.1 12.9 1.2 9.3 6.6 0.4 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) FSA_C PF10479.9 EGG23363.1 - 1.2 7.2 17.7 1.6 6.7 17.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus LPP20 PF02169.16 EGG23363.1 - 5.3 7.5 12.2 74 3.8 0.0 2.6 3 0 0 3 3 3 0 LPP20 lipoprotein MGC-24 PF05283.11 EGG23363.1 - 6.4 7.2 20.4 15 6.0 20.4 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TPR_1 PF00515.28 EGG23365.1 - 2.4e-18 65.1 9.8 7.2e-05 22.4 0.1 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGG23365.1 - 4.2e-17 60.8 4.4 0.0096 16.0 0.1 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG23365.1 - 6.6e-13 47.8 9.8 0.062 13.5 0.0 7.5 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG23365.1 - 1e-11 45.2 3.8 0.012 16.1 0.0 5.8 5 1 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG23365.1 - 6.1e-11 42.4 8.0 4.7e-05 23.5 0.0 5.4 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGG23365.1 - 5.5e-10 39.4 6.8 0.17 12.2 1.1 6.1 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGG23365.1 - 1.1e-08 34.6 2.8 0.0015 18.1 0.2 4.9 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 EGG23365.1 - 3.2e-08 33.7 0.3 3.4 8.7 0.0 6.6 4 2 3 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGG23365.1 - 4.9e-06 27.1 0.0 0.48 11.1 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG23365.1 - 1.4e-05 25.1 0.5 0.0034 17.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG23365.1 - 0.00024 20.9 2.2 3.9 7.7 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.8 EGG23365.1 - 0.0005 19.1 5.0 0.015 14.2 0.0 3.3 3 2 1 4 4 4 1 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 EGG23365.1 - 0.001 18.3 2.6 1.9 7.7 0.0 4.0 3 1 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGG23365.1 - 0.003 17.0 0.1 0.016 14.6 0.0 2.4 3 0 0 3 3 2 1 SHNi-TPR TPR_MalT PF17874.1 EGG23365.1 - 0.0083 15.5 7.4 0.026 13.9 0.9 2.8 2 1 0 3 3 3 1 MalT-like TPR region TPR_6 PF13174.6 EGG23365.1 - 0.025 15.2 1.7 7 7.5 0.0 5.4 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGG23365.1 - 0.047 13.6 1.0 28 4.8 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 EGG23365.1 - 0.059 12.8 1.6 0.54 9.6 0.1 2.8 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP HrpB1_HrpK PF09613.10 EGG23365.1 - 0.068 12.8 0.7 10 5.8 0.2 3.5 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF627 PF04781.12 EGG23365.1 - 0.079 13.0 1.5 3.2 7.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF627) MIT PF04212.18 EGG23365.1 - 0.18 11.9 11.3 0.6 10.2 0.7 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Imm5 PF14423.6 EGG23365.1 - 0.93 9.7 4.4 0.65 10.2 1.3 2.1 2 0 0 2 2 2 0 Immunity protein Imm5 MMM1 PF10296.9 EGG23366.1 - 1.1e-15 57.5 8.0 7.6e-15 54.8 8.0 2.2 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DUF4834 PF16118.5 EGG23366.1 - 4.1 8.4 5.4 20 6.2 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF775 PF05603.12 EGG23367.1 - 5.3e-45 153.4 3.9 7.1e-45 153.0 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) ERCC4 PF02732.15 EGG23368.1 - 2.3e-10 40.9 3.7 2.3e-10 40.9 0.8 2.3 1 1 1 2 2 2 1 ERCC4 domain RabGAP-TBC PF00566.18 EGG23369.1 - 5e-35 121.1 1.5 5e-35 121.1 1.5 4.4 4 3 0 4 4 4 1 Rab-GTPase-TBC domain YL1 PF05764.13 EGG23369.1 - 4.3 7.4 9.6 0.26 11.4 0.5 2.8 3 0 0 3 3 3 0 YL1 nuclear protein OSCP PF00213.18 EGG23370.1 - 4.8e-15 56.1 0.4 4.8e-15 56.1 0.4 2.1 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit DUF3391 PF11871.8 EGG23370.1 - 0.0068 17.0 0.7 0.015 15.9 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) GAS PF13851.6 EGG23370.1 - 0.011 15.1 1.0 0.017 14.5 0.2 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding zf-B_box PF00643.24 EGG23371.1 - 1.9e-08 34.3 4.3 1.9e-08 34.3 4.3 3.1 2 1 0 2 2 2 1 B-box zinc finger zf-RING_2 PF13639.6 EGG23371.1 - 2.8e-07 30.7 13.3 2.8e-07 30.7 13.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGG23371.1 - 1.9e-06 27.6 10.1 1.9e-06 27.6 10.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG23371.1 - 0.00011 22.0 13.1 0.00011 22.0 13.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG23371.1 - 0.00048 19.9 14.3 0.00048 19.9 14.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGG23371.1 - 0.007 16.6 10.0 0.007 16.6 10.0 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain C1_4 PF07975.12 EGG23371.1 - 0.066 13.5 17.5 0.064 13.5 3.3 2.9 2 0 0 2 2 2 0 TFIIH C1-like domain IBR PF01485.21 EGG23371.1 - 8.9 6.6 22.7 8.9 6.6 10.6 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Ank_4 PF13637.6 EGG23372.1 - 2.8e-44 149.0 2.3 1.2e-06 28.9 0.0 8.0 7 2 0 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG23372.1 - 8.4e-43 144.9 2.9 8e-09 36.0 0.1 7.2 2 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG23372.1 - 1.6e-32 111.1 6.0 0.0093 16.3 0.0 12.7 3 2 9 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23372.1 - 6.1e-27 90.7 2.0 0.37 11.5 0.0 12.4 12 1 1 13 13 13 7 Ankyrin repeat DUF5049 PF16468.5 EGG23372.1 - 2.5e-17 62.5 12.6 0.99 9.3 0.0 9.6 4 3 5 9 9 9 7 Domain of unknown function (DUF5049) Ank PF00023.30 EGG23372.1 - 1.8e-10 40.8 1.0 1.8 9.2 0.0 10.0 5 4 3 8 8 8 1 Ankyrin repeat YAcAr PF10686.9 EGG23372.1 - 0.0096 15.9 3.4 17 5.4 0.0 4.1 3 1 1 4 4 4 1 YspA, cpYpsA-related SLOG family VHL_C PF17211.3 EGG23372.1 - 0.11 12.5 0.4 13 5.9 0.0 4.2 5 0 0 5 5 5 0 VHL box domain T6SS_HCP PF05638.12 EGG23372.1 - 0.24 11.8 2.6 0.9 9.9 0.1 2.9 2 2 0 2 2 2 0 Type VI secretion system effector, Hcp Porin_3 PF01459.22 EGG23377.1 - 2.9e-29 102.4 0.9 2.9e-29 102.4 0.9 2.4 2 0 0 2 2 2 1 Eukaryotic porin Acetyltransf_1 PF00583.25 EGG23377.1 - 4.3e-09 36.6 0.0 1.1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG23377.1 - 4.5e-09 36.6 0.0 1.1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG23377.1 - 1.9e-07 30.9 0.0 4.8e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EGG23377.1 - 6.1e-07 29.4 0.0 1.9e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGG23377.1 - 0.012 15.7 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 EGG23378.1 - 4.2e-05 23.0 0.7 8.5e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Prominin PF05478.11 EGG23378.1 - 0.0041 15.2 1.8 0.0061 14.6 1.8 1.3 1 0 0 1 1 1 1 Prominin Ndc1_Nup PF09531.10 EGG23378.1 - 0.092 11.4 15.0 0.12 11.0 15.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 EGG23378.1 - 2.8 6.1 24.3 3.7 5.7 24.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.25 EGG23379.1 - 5.2e-47 160.4 0.2 8.1e-47 159.8 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23379.1 - 6.9e-22 78.0 0.0 9.3e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG23379.1 - 3.8e-05 23.1 0.0 0.0002 20.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGG23379.1 - 0.0064 15.3 0.2 0.013 14.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGG23379.1 - 0.03 13.7 0.1 0.048 13.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGG23379.1 - 0.034 13.8 0.1 0.83 9.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Sec39 PF08314.11 EGG23379.1 - 0.048 12.1 0.1 0.063 11.7 0.1 1.1 1 0 0 1 1 1 0 Secretory pathway protein Sec39 Lipoprotein_2 PF00921.17 EGG23379.1 - 0.1 12.1 4.4 0.16 11.5 4.4 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein RasGAP PF00616.19 EGG23380.1 - 1.4e-33 116.4 2.6 5.9e-21 75.1 0.1 2.7 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EGG23380.1 - 5e-23 81.4 1.1 1.4e-21 76.7 0.3 2.5 2 0 0 2 2 2 1 C2 domain Nop14 PF04147.12 EGG23381.1 - 0.00037 18.9 21.1 0.00037 18.9 21.1 1.8 2 0 0 2 2 2 1 Nop14-like family CDC45 PF02724.14 EGG23381.1 - 0.0031 15.9 14.2 0.0044 15.4 14.2 1.3 1 0 0 1 1 1 1 CDC45-like protein DNA_pol_phi PF04931.13 EGG23381.1 - 0.0037 15.4 24.3 0.0072 14.5 24.3 1.5 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 EGG23381.1 - 0.004 16.6 19.2 0.004 16.6 19.2 1.6 2 0 0 2 2 2 1 SDA1 Pes-10 PF07149.11 EGG23381.1 - 0.049 12.7 17.1 0.068 12.2 17.1 1.3 1 0 0 1 1 1 0 Pes-10 PPL5 PF18168.1 EGG23381.1 - 0.12 11.6 5.4 0.29 10.4 5.4 1.7 1 0 0 1 1 1 0 Prim-pol family 5 SID-1_RNA_chan PF13965.6 EGG23381.1 - 0.12 10.7 4.3 0.15 10.5 4.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RRN3 PF05327.11 EGG23381.1 - 0.33 9.4 15.3 0.54 8.7 15.3 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid_p PF12226.8 EGG23381.1 - 0.43 9.7 22.0 0.79 8.8 22.0 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SAPS PF04499.15 EGG23381.1 - 0.48 9.1 20.3 0.66 8.7 19.6 1.4 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4820 PF16091.5 EGG23381.1 - 0.63 9.4 11.9 0.058 12.7 6.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Serinc PF03348.15 EGG23381.1 - 1.5 7.7 2.9 2 7.2 2.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) BUD22 PF09073.10 EGG23381.1 - 2.5 7.3 31.1 0.038 13.3 23.6 1.6 2 0 0 2 2 2 0 BUD22 Hid1 PF12722.7 EGG23381.1 - 2.7 6.0 11.9 4.7 5.2 11.9 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CLN3 PF02487.17 EGG23381.1 - 3.3 6.6 5.6 7 5.6 5.6 1.5 1 0 0 1 1 1 0 CLN3 protein GREB1 PF15782.5 EGG23381.1 - 5.9 3.9 15.6 8.6 3.3 15.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2624 PF11116.8 EGG23381.1 - 6.9 7.6 8.4 19 6.2 0.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2624) Pox_Ag35 PF03286.14 EGG23381.1 - 8.5 6.1 23.8 0.44 10.3 16.8 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Paf1 PF03985.13 EGG23381.1 - 9.7 5.1 27.6 22 3.9 27.6 1.6 1 0 0 1 1 1 0 Paf1 MFS_1 PF07690.16 EGG23382.1 - 2.8e-11 42.9 41.4 2.8e-11 42.9 41.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 EGG23382.1 - 1.3e-09 37.1 12.6 1.3e-09 37.1 12.6 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein Glyco_hydro_15 PF00723.21 EGG23383.1 - 2.5e-53 181.5 0.0 5.6e-50 170.4 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 LSM PF01423.22 EGG23383.1 - 1.2e-16 60.1 0.5 2.5e-16 59.1 0.5 1.6 1 0 0 1 1 1 1 LSM domain MamL-1 PF09596.10 EGG23384.1 - 1.3 9.3 4.6 3.9 7.8 4.6 1.7 1 0 0 1 1 1 0 MamL-1 domain DUF5643 PF18705.1 EGG23384.1 - 4.1 7.4 18.5 0.17 11.8 7.5 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5643) GBP PF02263.19 EGG23385.1 - 5.3e-40 137.3 0.1 5.3e-40 137.3 0.1 1.9 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGG23385.1 - 3.3e-12 46.4 32.0 4.3e-12 46.0 29.5 2.2 1 1 0 1 1 1 1 Guanylate-binding protein, C-terminal domain GST_N_2 PF13409.6 EGG23386.1 - 8.3e-24 83.7 0.0 1.8e-22 79.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGG23386.1 - 3.4e-12 46.2 0.0 1.5e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG23386.1 - 1.6e-08 34.7 0.0 2.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG23386.1 - 6.1e-06 26.3 0.0 1.6e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGG23386.1 - 0.012 16.0 0.0 0.34 11.4 0.0 2.8 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EGG23386.1 - 0.018 14.9 0.1 0.044 13.6 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DCX PF03607.17 EGG23387.1 - 1.3e-30 105.2 2.0 2.9e-14 52.9 0.0 2.5 3 0 0 3 3 3 2 Doublecortin UB2H PF14814.6 EGG23387.1 - 0.019 14.9 0.0 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Bifunctional transglycosylase second domain DUF3942 PF13078.6 EGG23387.1 - 0.1 12.9 0.5 0.44 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3942) HHH_9 PF17674.1 EGG23387.1 - 0.13 13.2 0.0 18 6.3 0.0 2.4 2 0 0 2 2 2 0 HHH domain SoDot-IcmSS PF16848.5 EGG23387.1 - 0.16 12.0 0.1 6.5 6.7 0.1 2.2 2 0 0 2 2 2 0 Substrate of the Dot/Icm secretion system, putative USP7_C2 PF14533.6 EGG23387.1 - 0.26 11.0 1.6 2.7 7.7 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal TRAPP PF04051.16 EGG23388.1 - 9.7e-37 125.9 0.3 1.2e-36 125.6 0.3 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Synaptonemal_3 PF15191.6 EGG23388.1 - 0.0032 17.2 0.3 0.19 11.6 0.0 2.4 2 0 0 2 2 2 2 Synaptonemal complex central element protein 3 RhoGEF PF00621.20 EGG23389.1 - 2.3e-45 155.1 12.3 2.3e-45 155.1 12.3 2.1 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.31 EGG23389.1 - 1.5e-14 54.1 0.4 5.1e-14 52.4 0.0 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ_SEC7_PH PF16453.5 EGG23389.1 - 0.00078 19.4 2.0 0.0012 18.9 0.1 2.3 2 1 0 2 2 2 1 PH domain SUIM_assoc PF16619.5 EGG23389.1 - 0.014 15.4 6.8 0.014 15.4 6.8 4.4 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 IQ PF00612.27 EGG23389.1 - 0.023 14.5 1.2 0.063 13.1 1.2 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif PI_PP_I PF18363.1 EGG23389.1 - 0.72 10.1 6.4 2.7 8.2 1.9 3.3 3 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain Usp PF00582.26 EGG23390.1 - 1.6e-22 80.5 0.0 1.7e-21 77.2 0.0 2.0 1 1 0 1 1 1 1 Universal stress protein family Hce2 PF14856.6 EGG23390.1 - 0.034 14.4 0.3 2.2 8.6 0.0 2.3 1 1 0 2 2 2 0 Pathogen effector; putative necrosis-inducing factor YodL PF14191.6 EGG23390.1 - 0.086 13.7 0.1 0.13 13.1 0.1 1.3 1 0 0 1 1 1 0 YodL-like Acetyltransf_10 PF13673.7 EGG23392.1 - 7.7e-13 48.5 0.1 1.1e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG23392.1 - 2.1e-09 37.6 0.3 2.8e-09 37.2 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG23392.1 - 3.9e-08 33.6 0.3 5.9e-08 33.0 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGG23392.1 - 1.5e-06 28.3 0.1 2.5e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 EGG23392.1 - 4.1e-05 24.2 0.3 0.00026 21.6 0.3 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Autoind_synth PF00765.17 EGG23392.1 - 0.0013 18.3 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Autoinducer synthase FR47 PF08445.10 EGG23392.1 - 0.0027 17.6 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGG23392.1 - 0.0056 16.8 0.1 0.011 15.9 0.1 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase STAS PF01740.21 EGG23392.1 - 0.0075 15.9 0.1 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 STAS domain Pro_sub2 PF18513.1 EGG23392.1 - 0.32 11.2 2.3 0.91 9.7 0.1 2.4 2 1 1 3 3 3 0 Prodomain subtilisin 2 GATA PF00320.27 EGG23393.1 - 4.9e-14 51.7 8.6 4.9e-14 51.7 8.6 2.1 2 0 0 2 2 2 1 GATA zinc finger JIP_LZII PF16471.5 EGG23393.1 - 0.31 11.2 6.6 0.73 10.0 6.6 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II MCM PF00493.23 EGG23394.1 - 3.5e-102 340.3 1.0 6e-102 339.5 1.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGG23394.1 - 6.7e-37 126.2 0.2 1.4e-36 125.1 0.2 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGG23394.1 - 3e-26 91.6 1.9 3e-26 91.6 1.9 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EGG23394.1 - 5.4e-13 49.4 1.6 2.7e-12 47.2 0.0 2.7 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGG23394.1 - 1.6e-08 34.2 0.0 6.5e-07 28.9 0.0 2.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM2_N PF12619.8 EGG23394.1 - 1.9e-08 34.7 41.9 1.9e-08 34.7 41.9 2.6 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 AAA_5 PF07728.14 EGG23394.1 - 3.5e-06 27.1 0.0 1e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGG23394.1 - 6.8e-05 22.7 0.0 0.00094 19.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EGG23394.1 - 0.001 18.9 0.3 0.0034 17.2 0.3 1.9 1 0 0 1 1 1 1 AAA lid domain Sigma54_activat PF00158.26 EGG23394.1 - 0.0038 16.9 0.2 0.082 12.6 0.1 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 EGG23394.1 - 0.02 14.6 0.3 0.045 13.5 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGG23394.1 - 0.12 12.8 0.0 0.12 12.8 0.0 3.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Cyclin_N PF00134.23 EGG23395.1 - 3.7e-11 42.9 0.0 6.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGG23395.1 - 6.5e-09 36.4 0.1 1.9e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 Cyclin Macoilin PF09726.9 EGG23395.1 - 0.089 11.3 15.0 0.11 11.0 15.0 1.1 1 0 0 1 1 1 0 Macoilin family SelP_N PF04592.14 EGG23395.1 - 0.29 10.5 25.4 0.096 12.1 20.6 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Vma12 PF11712.8 EGG23395.1 - 2.3 8.3 4.7 11 6.1 0.0 3.1 2 1 1 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SNARE PF05739.19 EGG23396.1 - 3.9e-11 42.8 1.1 3.9e-11 42.8 1.1 2.9 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.25 EGG23396.1 - 0.0018 18.0 14.8 0.037 13.7 0.9 2.9 1 1 2 3 3 3 2 Syntaxin Tweety PF04906.13 EGG23396.1 - 0.049 12.3 4.9 1.1 7.8 0.3 2.2 2 0 0 2 2 2 0 Tweety DotA PF11388.8 EGG23396.1 - 0.13 12.4 0.3 0.13 12.4 0.3 2.5 2 1 1 3 3 3 0 Phagosome trafficking protein DotA SKIP_SNW PF02731.15 EGG23397.1 - 3.7e-64 215.2 2.9 3.7e-64 215.2 2.9 2.9 4 0 0 4 4 4 1 SKIP/SNW domain Dus PF01207.17 EGG23397.1 - 5.7e-47 160.3 0.0 1.3e-46 159.1 0.0 1.6 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) COG5 PF10392.9 EGG23397.1 - 3.6 7.8 6.9 0.44 10.7 0.8 2.6 4 0 0 4 4 4 0 Golgi transport complex subunit 5 RasGEF PF00617.19 EGG23398.1 - 9.7e-61 205.0 1.0 1.1e-60 204.8 0.1 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGG23398.1 - 2.9e-23 82.1 3.9 1.1e-22 80.2 0.1 3.2 3 0 0 3 3 3 1 RasGEF N-terminal motif SpoU_methylase PF00588.19 EGG23399.1 - 4.6e-35 120.9 0.0 1.1e-34 119.7 0.0 1.6 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EGG23399.1 - 1.6e-07 31.5 0.0 1.1e-06 28.8 0.0 2.3 3 0 0 3 3 3 1 RNA 2'-O ribose methyltransferase substrate binding DUF2458 PF10454.9 EGG23399.1 - 0.016 14.9 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) WD40 PF00400.32 EGG23400.1 - 2.4e-46 154.8 25.2 3.9e-05 24.3 0.1 10.9 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG23400.1 - 8.8e-16 58.0 7.9 9.5e-06 25.8 0.1 7.2 2 2 7 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EGG23400.1 - 5.7e-15 55.6 0.1 1.1e-14 54.7 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 EGG23400.1 - 2.7e-08 33.5 0.5 0.00052 19.4 0.1 3.4 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 EGG23400.1 - 7.3e-06 25.2 11.8 0.19 10.6 4.4 5.3 3 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGG23400.1 - 0.0021 16.8 12.8 0.88 8.1 0.0 5.1 4 1 1 5 5 5 2 Nucleoporin Nup120/160 ELYS-bb PF16687.5 EGG23400.1 - 0.019 13.6 0.1 0.48 9.0 0.0 2.5 3 0 0 3 3 3 0 beta-propeller of ELYS nucleoporin Nucleoporin_N PF08801.11 EGG23400.1 - 0.039 12.7 14.9 0.62 8.7 2.3 5.5 3 2 0 3 3 3 0 Nup133 N terminal like AAT PF03417.16 EGG23401.1 - 0.0036 17.0 0.0 0.028 14.1 0.0 2.3 3 0 0 3 3 3 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase BPL_LplA_LipB PF03099.19 EGG23402.1 - 1e-19 70.7 0.0 1.7e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EGG23402.1 - 3.9e-08 33.1 0.0 7.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Med15_fungi PF05397.12 EGG23402.1 - 0.13 12.5 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 15 Metallophos_C PF14008.6 EGG23403.1 - 9.6e-22 77.6 0.6 9.6e-22 77.6 0.6 3.5 4 0 0 4 4 4 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EGG23403.1 - 2.3e-14 53.7 0.2 1e-13 51.7 0.2 2.1 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 EGG23403.1 - 6.1e-13 49.7 2.0 1.3e-12 48.6 1.9 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase fn3_PAP PF17808.1 EGG23403.1 - 0.00018 21.6 0.1 0.029 14.5 0.1 2.9 2 1 0 2 2 2 1 Fn3-like domain from Purple Acid Phosphatase PhoD_N PF16655.5 EGG23403.1 - 0.094 13.3 0.0 0.3 11.7 0.0 1.8 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Maf PF02545.14 EGG23404.1 - 3.1e-25 88.9 0.2 3.4e-25 88.8 0.2 1.0 1 0 0 1 1 1 1 Maf-like protein IlvB_leader PF08049.11 EGG23404.1 - 0.02 14.8 0.8 0.04 13.8 0.8 1.5 1 0 0 1 1 1 0 IlvB leader peptide WRKY PF03106.15 EGG23405.1 - 5e-46 154.8 12.4 7.7e-24 83.7 5.2 3.2 2 0 0 2 2 2 2 WRKY DNA -binding domain UBA_e1_thiolCys PF10585.9 EGG23406.1 - 6.6e-24 85.2 1.2 9.7e-24 84.7 0.3 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EGG23406.1 - 4.4e-18 65.8 0.5 2.1e-16 60.4 0.1 2.7 2 0 0 2 2 2 1 Ubiquitin fold domain ThiF PF00899.21 EGG23406.1 - 1.5e-11 44.1 0.0 2.5e-07 30.3 0.0 2.6 2 1 0 2 2 2 2 ThiF family E1_4HB PF16191.5 EGG23406.1 - 0.0027 17.9 0.0 0.0076 16.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle RICTOR_phospho PF14665.6 EGG23407.1 - 0.028 14.8 2.3 0.074 13.4 0.3 2.2 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site DUF3439 PF11921.8 EGG23407.1 - 0.048 13.6 8.0 0.073 13.0 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGG23407.1 - 4 5.5 12.0 5.1 5.2 12.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Peptidase_M49 PF03571.15 EGG23409.1 - 4e-228 758.3 2.6 2.8e-227 755.5 0.0 2.6 2 0 0 2 2 2 1 Peptidase family M49 Pyridoxal_deC PF00282.19 EGG23409.1 - 3e-15 55.8 0.0 5.4e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGG23409.1 - 2.3e-13 49.9 0.0 6.4e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGG23409.1 - 0.00025 20.5 0.3 0.00062 19.2 0.3 1.6 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DFRP_C PF16543.5 EGG23410.1 - 6e-22 77.9 3.5 6e-22 77.9 3.5 4.3 4 1 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 EGG23410.1 - 1.2e-07 31.4 7.0 1.1e-05 25.2 0.7 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGG23410.1 - 1.2e-06 28.1 6.1 1.4e-05 24.7 1.0 3.0 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGG23410.1 - 1.5e-06 28.1 15.9 1.1e-05 25.3 5.6 3.0 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 EGG23410.1 - 2.6e-06 28.1 19.0 7.1e-05 23.5 5.7 3.8 2 1 1 3 3 3 2 Torus domain NUC153 PF08159.12 EGG23410.1 - 0.0036 17.1 2.3 0.0057 16.4 0.8 2.1 1 1 1 2 2 2 2 NUC153 domain zf-CCCH_3 PF15663.5 EGG23410.1 - 0.0047 17.1 5.0 0.022 14.9 0.0 2.9 3 0 0 3 3 3 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGG23410.1 - 0.024 15.1 10.5 0.98 10.0 5.0 2.6 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger C2 PF00168.30 EGG23412.1 - 6.2e-19 68.2 0.1 1.7e-18 66.8 0.1 1.8 1 0 0 1 1 1 1 C2 domain Arrestin_C PF02752.22 EGG23412.1 - 3.3e-16 59.9 3.8 3.6e-16 59.8 1.5 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGG23412.1 - 5.2e-14 52.5 3.7 5.8e-07 29.7 0.1 3.7 2 2 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 EGG23412.1 - 0.00093 18.5 1.5 0.07 12.3 0.1 2.7 3 0 0 3 3 3 1 Rgp1 DUF4352 PF11611.8 EGG23412.1 - 0.0014 18.9 1.5 0.0022 18.3 0.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4352) LDB19 PF13002.7 EGG23412.1 - 0.0047 16.7 0.0 0.045 13.5 0.0 2.2 2 0 0 2 2 2 1 Arrestin_N terminal like CBM49 PF09478.10 EGG23412.1 - 0.018 15.3 0.1 0.057 13.7 0.1 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 DUF4625 PF15418.6 EGG23412.1 - 0.044 14.0 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) DUF2393 PF09624.10 EGG23412.1 - 0.046 13.7 0.6 0.12 12.3 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DUF824 PF05688.11 EGG23412.1 - 0.14 12.0 0.1 0.51 10.2 0.1 2.0 1 1 1 2 2 2 0 Salmonella repeat of unknown function (DUF824) Rad51 PF08423.11 EGG23414.1 - 2.6e-122 407.0 0.0 3.2e-122 406.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EGG23414.1 - 6.5e-12 45.5 0.1 1e-11 44.9 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EGG23414.1 - 1.2e-08 35.5 0.6 3.5e-08 33.9 0.3 2.0 2 1 0 2 2 2 1 Helix-hairpin-helix domain AAA_25 PF13481.6 EGG23414.1 - 3.3e-08 33.3 0.0 6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EGG23414.1 - 8.4e-07 28.6 0.0 8.4e-07 28.6 0.0 2.2 2 1 0 2 2 2 1 KaiC AAA_24 PF13479.6 EGG23414.1 - 0.0066 16.2 0.1 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma70_ner PF04546.13 EGG23414.1 - 0.39 10.6 5.9 0.62 9.9 5.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region FH2 PF02181.23 EGG23416.1 - 1.5e-87 294.2 2.0 1.5e-87 294.2 2.0 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EGG23416.1 - 2.1e-35 122.0 1.8 7.8e-35 120.1 1.8 2.1 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGG23416.1 - 4.3e-21 75.4 8.2 8.2e-21 74.5 6.9 2.2 2 1 0 2 2 2 1 Diaphanous FH3 Domain SlyX PF04102.12 EGG23416.1 - 0.2 12.3 5.2 0.57 10.8 1.5 3.8 3 0 0 3 3 3 0 SlyX DUF489 PF04356.12 EGG23416.1 - 0.29 11.1 4.0 12 5.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF489) FlgN PF05130.12 EGG23416.1 - 1.3 9.6 13.7 0.079 13.5 4.7 3.3 3 1 1 4 4 4 0 FlgN protein APG6_N PF17675.1 EGG23416.1 - 1.6 9.2 16.7 0.87 10.1 5.7 4.0 2 1 0 3 3 3 0 Apg6 coiled-coil region DUF4164 PF13747.6 EGG23416.1 - 2.6 8.4 9.0 1 9.7 3.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) FmiP_Thoc5 PF09766.9 EGG23416.1 - 6 6.1 12.3 0.43 9.8 2.3 3.0 3 0 0 3 3 3 0 Fms-interacting protein/Thoc5 Rab5-bind PF09311.11 EGG23416.1 - 6.6 6.0 15.2 0.035 13.5 5.0 2.4 3 0 0 3 3 3 0 Rabaptin-like protein DUF4407 PF14362.6 EGG23416.1 - 8.2 5.7 8.7 4 6.7 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 EGG23418.1 - 2.2e-72 243.6 0.0 3.3e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23418.1 - 8.5e-32 110.4 0.0 1.3e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGG23418.1 - 5.1e-17 62.0 0.5 1.4e-16 60.6 0.1 2.0 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EGG23418.1 - 1.1e-08 35.3 0.0 4.4e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 EGG23418.1 - 4e-07 29.6 0.0 6.5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG23418.1 - 0.00087 18.7 0.0 0.0028 17.1 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG23418.1 - 0.0074 16.2 0.0 0.058 13.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family FHA_2 PF17913.1 EGG23418.1 - 0.02 15.1 0.1 0.05 13.9 0.1 1.6 1 0 0 1 1 1 0 FHA domain SET PF00856.28 EGG23419.1 - 9.5e-18 65.2 0.1 9.5e-18 65.2 0.1 4.5 3 1 0 3 3 3 1 SET domain RRM_1 PF00076.22 EGG23419.1 - 1.6e-10 40.7 0.0 3.7e-09 36.3 0.0 2.7 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_4 PF07993.12 EGG23421.1 - 2.1e-61 207.3 0.0 3.7e-61 206.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 EGG23421.1 - 2.6e-21 75.7 0.0 7.3e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 Acyltransferase Sterile PF03015.19 EGG23421.1 - 1.4e-19 70.1 1.0 4.3e-19 68.5 1.0 1.9 1 0 0 1 1 1 1 Male sterility protein SET PF00856.28 EGG23421.1 - 5.7e-07 30.1 0.6 8e-05 23.1 0.1 3.3 2 1 0 2 2 2 1 SET domain Ank_2 PF12796.7 EGG23421.1 - 4.2e-06 27.3 0.3 6.9e-05 23.4 0.2 2.8 3 0 0 3 3 2 1 Ankyrin repeats (3 copies) Epimerase PF01370.21 EGG23421.1 - 1.9e-05 24.2 0.0 8.2e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGG23421.1 - 0.0024 17.4 0.4 0.023 14.1 0.4 2.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Ank_4 PF13637.6 EGG23421.1 - 0.015 15.9 0.3 0.31 11.7 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) 3Beta_HSD PF01073.19 EGG23421.1 - 0.019 14.0 1.3 0.28 10.1 0.8 2.6 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ank_3 PF13606.6 EGG23421.1 - 0.031 14.8 0.8 4.6 8.1 0.0 3.9 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 EGG23421.1 - 0.058 13.7 0.1 0.21 12.0 0.1 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 EGG23421.1 - 0.16 12.5 1.1 0.5 10.9 0.0 2.5 3 0 0 3 3 1 0 Ankyrin repeat Tma16 PF11176.8 EGG23421.1 - 3.3 7.6 8.4 9.2 6.1 6.6 2.4 2 0 0 2 2 2 0 Translation machinery-associated protein 16 PseudoU_synth_2 PF00849.22 EGG23422.1 - 3.3e-25 89.0 11.5 6.4e-21 75.1 11.5 4.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EGG23422.1 - 0.0048 16.6 1.1 0.019 14.7 0.6 2.1 2 0 0 2 2 2 1 S4 domain BUD22 PF09073.10 EGG23422.1 - 0.0054 16.1 32.0 0.0054 16.1 32.0 2.0 2 0 0 2 2 2 1 BUD22 S4_2 PF13275.6 EGG23422.1 - 0.011 15.5 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 S4 domain CDC27 PF09507.10 EGG23422.1 - 3.1 7.1 38.9 0.3 10.4 31.9 2.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Arf PF00025.21 EGG23423.1 - 5.8e-60 201.7 0.1 7e-60 201.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGG23423.1 - 2.5e-15 56.7 0.1 4.7e-15 55.9 0.0 1.5 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG23423.1 - 1.2e-11 44.4 0.0 1.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGG23423.1 - 7.7e-11 41.7 0.3 1.2e-10 41.1 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGG23423.1 - 5.5e-10 39.0 0.0 7.3e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGG23423.1 - 3.5e-08 33.0 2.1 7.9e-05 22.0 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EGG23423.1 - 6.4e-07 29.5 0.3 1.7e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 EGG23423.1 - 0.0034 17.8 0.0 0.0052 17.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EGG23423.1 - 0.0086 16.0 0.1 3.9 7.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase IES5 PF17335.2 EGG23423.1 - 0.013 15.8 0.4 0.32 11.3 0.1 2.8 1 1 2 3 3 3 0 Ino80 complex subunit 5 MobB PF03205.14 EGG23423.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 EGG23423.1 - 0.044 13.3 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NAD_binding_6 PF08030.12 EGG23423.1 - 0.065 13.3 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Ferric reductase NAD binding domain AAA_22 PF13401.6 EGG23423.1 - 0.097 12.9 0.2 0.31 11.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EGG23423.1 - 0.098 12.2 0.4 0.92 9.1 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EGG23423.1 - 0.1 12.5 0.3 1.4 8.8 0.3 2.3 1 1 0 1 1 1 0 NACHT domain RNF220 PF15926.5 EGG23423.1 - 0.13 11.8 0.1 0.91 9.1 0.0 1.9 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 ABC_tran PF00005.27 EGG23423.1 - 0.13 12.8 0.1 0.16 12.4 0.1 1.5 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 EGG23423.1 - 0.16 11.6 0.2 0.47 10.1 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 EGG23423.1 - 0.19 12.1 0.1 1 9.7 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain RRM_1 PF00076.22 EGG23425.1 - 1e-19 70.1 0.0 6.1e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 EGG23426.1 - 6.1e-12 46.5 0.3 1.3e-11 45.4 0.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SapB_2 PF03489.17 EGG23426.1 - 0.015 15.4 0.5 0.23 11.6 0.2 2.5 2 0 0 2 2 2 0 Saposin-like type B, region 2 DUF3915 PF13054.6 EGG23426.1 - 0.96 9.4 5.7 2.5 8.1 5.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) Apis_Csd PF11671.8 EGG23426.1 - 3.6 7.6 15.0 0.14 12.1 2.8 3.2 3 0 0 3 3 3 0 Complementary sex determiner protein Aldedh PF00171.22 EGG23429.1 - 1.6e-136 455.5 1.0 1.9e-136 455.3 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family C9orf72-like PF15019.6 EGG23430.1 - 9.4e-40 136.7 8.4 1.9e-39 135.7 8.4 1.5 1 0 0 1 1 1 1 C9orf72-like protein family PsbP PF01789.16 EGG23431.1 - 5.8e-07 29.8 2.4 6.6e-05 23.1 0.1 3.3 3 1 0 3 3 3 2 PsbP Pkinase PF00069.25 EGG23432.1 - 6.1e-51 173.3 0.0 1.2e-50 172.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23432.1 - 1.4e-48 165.5 0.0 2.2e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUSP PF06337.12 EGG23432.1 - 2.3e-13 50.6 0.0 2.3e-13 50.6 0.0 5.0 3 1 0 3 3 3 1 DUSP domain Ubiquitin_3 PF14836.6 EGG23432.1 - 0.003 17.5 0.1 0.0087 16.0 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain APH PF01636.23 EGG23432.1 - 0.04 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG23432.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Integrase_H2C2 PF17921.1 EGG23434.1 - 4.8e-06 26.6 0.3 1.5e-05 25.0 0.3 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain TFIIA PF03153.13 EGG23434.1 - 0.074 13.0 35.3 0.043 13.8 31.3 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MtrG PF04210.13 EGG23434.1 - 0.15 12.0 0.1 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G ALMT PF11744.8 EGG23434.1 - 1.1 8.0 19.0 1.9 7.2 19.0 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter HSP70 PF00012.20 EGG23434.1 - 3.1 5.9 20.8 4.8 5.2 20.8 1.2 1 0 0 1 1 1 0 Hsp70 protein Wax2_C PF12076.8 EGG23434.1 - 6.1 6.5 9.0 19 5.0 0.0 3.7 3 1 1 4 4 4 0 WAX2 C-terminal domain KaiA PF07688.12 EGG23436.1 - 0.068 13.3 0.4 0.068 13.3 0.4 3.1 3 0 0 3 3 3 0 KaiA C-terminal domain AftA_C PF12249.8 EGG23438.1 - 0.022 14.5 0.1 2.3 7.9 0.0 2.7 2 1 0 2 2 2 0 Arabinofuranosyltransferase A C terminal DUF3844 PF12955.7 EGG23438.1 - 0.054 13.6 4.1 0.34 11.0 2.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) EGF_2 PF07974.13 EGG23438.1 - 0.058 13.8 10.6 0.15 12.4 10.6 1.7 1 0 0 1 1 1 0 EGF-like domain Glyco_transf_17 PF04724.13 EGG23439.1 - 9.4e-17 61.1 0.1 1.6e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 ORC6 PF05460.13 EGG23441.1 - 9.6 5.4 15.5 13 4.9 15.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Chlam_PMP PF02415.17 EGG23442.1 - 0.0046 17.4 61.6 0.19 12.3 0.0 11.3 10 2 0 10 10 10 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat UL41A PF17591.2 EGG23442.1 - 0.052 13.7 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Herpesvirus UL41A Podoplanin PF05808.11 EGG23442.1 - 0.1 12.7 3.6 0.37 10.9 3.6 1.9 1 0 0 1 1 1 0 Podoplanin DUF5123 PF17161.4 EGG23442.1 - 0.11 13.6 0.4 0.11 13.6 0.4 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF5123) DUF2251 PF10008.9 EGG23444.1 - 0.064 13.4 1.2 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2251) RhoGEF PF00621.20 EGG23445.1 - 7.2e-40 137.2 3.1 7.2e-40 137.2 3.1 1.9 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 EGG23445.1 - 1.1e-19 70.3 8.6 2.7e-19 69.0 8.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 EGG23445.1 - 7.5e-08 32.8 0.2 2.3e-07 31.3 0.2 1.9 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 EGG23445.1 - 1.1e-06 28.5 0.3 4.9e-06 26.4 0.4 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain FYVE_2 PF02318.16 EGG23445.1 - 0.003 17.8 3.7 0.003 17.8 3.7 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger PhoU PF01895.19 EGG23445.1 - 0.14 12.6 0.1 0.49 10.9 0.1 2.0 1 0 0 1 1 1 0 PhoU domain Vps39_1 PF10366.9 EGG23445.1 - 0.49 10.7 0.0 0.49 10.7 0.0 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-B_box PF00643.24 EGG23445.1 - 1.2 9.3 5.2 2.4 8.4 5.2 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-UBP PF02148.19 EGG23445.1 - 2.5 8.5 8.9 0.17 12.2 3.5 1.9 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Chromo PF00385.24 EGG23446.1 - 2.3e-14 53.0 1.7 6.2e-14 51.6 1.7 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EGG23446.1 - 0.00059 19.9 0.1 0.001 19.2 0.1 1.3 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 DnaJ PF00226.31 EGG23447.1 - 5.7e-05 23.2 0.3 0.00051 20.1 0.0 2.9 2 0 0 2 2 2 1 DnaJ domain Cys_rich_KTR PF14205.6 EGG23447.1 - 0.00062 19.5 0.9 0.0025 17.6 0.9 2.0 1 0 0 1 1 1 1 Cysteine-rich KTR Syja_N PF02383.18 EGG23448.1 - 2.9e-84 283.1 8.4 6.6e-84 281.9 8.4 1.6 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EGG23448.1 - 4.8e-26 90.7 0.4 1.2e-25 89.5 0.4 1.7 1 0 0 1 1 1 1 Inositol phosphatase PPTA PF01239.22 EGG23451.1 - 3e-45 150.7 14.2 4.6e-11 42.1 0.0 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF5446 PF17522.2 EGG23451.1 - 0.12 12.6 0.0 0.48 10.6 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5446) HECT_2 PF09814.9 EGG23452.1 - 6.1e-28 97.8 8.9 8.2e-28 97.3 8.9 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 EGG23452.1 - 0.016 15.4 6.2 0.32 11.2 4.8 3.2 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Eapp_C PF10238.9 EGG23452.1 - 0.03 14.4 1.2 0.058 13.5 0.2 2.0 2 0 0 2 2 2 0 E2F-associated phosphoprotein Ras PF00071.22 EGG23453.1 - 5.8e-48 162.5 0.6 3.9e-39 133.8 0.2 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 EGG23453.1 - 1.1e-25 90.1 1.0 1.2e-16 61.0 0.1 2.4 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG23453.1 - 1.6e-08 34.2 0.6 1.4e-07 31.2 0.6 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGG23453.1 - 0.00014 21.8 0.3 0.23 11.4 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGG23453.1 - 0.00045 19.8 0.2 0.0028 17.2 0.1 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain TniB PF05621.11 EGG23453.1 - 0.021 14.3 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 EGG23453.1 - 0.024 15.0 0.0 0.036 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 EGG23453.1 - 0.051 13.0 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGG23453.1 - 0.055 13.0 0.0 6 6.4 0.0 2.3 1 1 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGG23453.1 - 0.07 13.2 0.1 1.3 9.1 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EGG23453.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGG23453.1 - 0.13 12.0 0.1 0.5 10.1 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGG23454.1 - 3.5e-35 121.1 0.6 1.7e-34 118.8 0.1 2.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EGG23454.1 - 3.3e-18 65.8 0.0 8.1e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG23454.1 - 5.1e-07 29.4 0.0 2.3e-06 27.3 0.0 2.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG23454.1 - 2.5e-06 27.5 0.1 2.5e-06 27.5 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EGG23454.1 - 5e-06 26.7 1.1 1.7e-05 25.0 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGG23454.1 - 5.9e-06 26.0 0.5 1.4e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Ras family FeoB_N PF02421.18 EGG23454.1 - 0.0025 17.3 0.5 0.0069 15.9 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.6 EGG23454.1 - 0.0099 16.2 0.0 0.1 12.9 0.0 2.9 1 0 0 1 1 1 1 AAA domain UPF0147 PF03685.13 EGG23454.1 - 0.055 13.5 1.3 20 5.4 0.0 4.1 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0147) cobW PF02492.19 EGG23454.1 - 0.072 12.7 1.8 0.26 10.9 0.3 2.5 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3430 PF11912.8 EGG23455.1 - 0.023 14.7 0.3 0.023 14.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3430) Bactofilin PF04519.13 EGG23455.1 - 0.17 12.2 5.2 6.1 7.2 0.3 3.2 3 0 0 3 3 3 0 Polymer-forming cytoskeletal SNARE PF05739.19 EGG23456.1 - 7.6e-06 25.8 6.8 7.6e-06 25.8 6.8 2.2 2 1 0 2 2 2 1 SNARE domain Use1 PF09753.9 EGG23456.1 - 0.00035 20.4 1.9 0.00039 20.2 1.9 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 SLX9 PF15341.6 EGG23456.1 - 0.00084 19.7 0.2 0.001 19.4 0.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF2207 PF09972.9 EGG23456.1 - 0.0025 16.6 0.0 0.0026 16.6 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF745 PF05335.13 EGG23456.1 - 0.022 14.5 2.5 0.028 14.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Amnionless PF14828.6 EGG23456.1 - 0.058 12.2 0.6 0.059 12.2 0.6 1.0 1 0 0 1 1 1 0 Amnionless Orf78 PF06024.12 EGG23456.1 - 0.1 12.9 3.0 0.15 12.3 3.0 1.6 1 1 0 1 1 1 0 Orf78 (ac78) Cir_Bir_Yir PF06022.11 EGG23456.1 - 0.11 12.0 4.9 0.069 12.6 3.8 1.2 1 1 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Synaptobrevin PF00957.21 EGG23456.1 - 0.89 9.4 16.5 10 6.0 16.5 2.1 1 1 0 1 1 1 0 Synaptobrevin 60KD_IMP PF02096.20 EGG23456.1 - 4.7 7.1 7.5 1.4e+02 2.3 7.5 2.1 1 1 0 1 1 1 0 60Kd inner membrane protein WD40 PF00400.32 EGG23457.1 - 0.00021 22.0 2.2 6.4 7.8 0.1 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG23457.1 - 0.052 13.9 0.0 24 5.3 0.0 3.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 EGG23458.1 - 7.9e-24 82.5 31.5 8.9e-06 25.3 0.1 8.8 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGG23458.1 - 9.6e-24 81.6 30.6 0.0064 16.5 0.0 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat ANAPC8 PF04049.13 EGG23458.1 - 1.1e-22 80.7 4.1 1.1e-22 80.7 4.1 3.4 3 1 1 4 4 4 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 EGG23458.1 - 2e-20 71.7 9.7 0.024 15.5 0.0 8.3 6 3 3 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGG23458.1 - 6e-18 63.5 29.0 0.0053 16.9 0.0 10.2 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGG23458.1 - 8.9e-12 44.5 9.2 2.6e-06 27.0 0.2 5.7 3 2 2 5 5 5 2 TPR repeat TPR_19 PF14559.6 EGG23458.1 - 1.3e-11 44.8 10.9 1.2 9.7 0.0 7.6 5 3 1 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGG23458.1 - 1.4e-10 41.3 26.5 0.00034 20.9 2.5 8.5 7 3 1 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG23458.1 - 3.7e-10 40.3 4.3 0.0034 18.0 0.0 5.8 4 1 3 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG23458.1 - 1.7e-06 28.0 15.7 0.12 12.8 0.0 8.6 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG23458.1 - 2.2e-05 24.8 22.3 0.87 10.4 0.0 9.3 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGG23458.1 - 4.5e-05 23.5 2.9 0.32 11.2 0.0 4.6 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG23458.1 - 0.00011 22.0 22.4 0.037 14.0 0.3 6.6 9 0 0 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG23458.1 - 0.00084 19.5 34.9 0.16 12.2 0.4 6.9 3 1 4 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 EGG23458.1 - 0.00095 18.3 1.0 0.034 13.1 0.0 3.0 1 1 2 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 EGG23458.1 - 0.018 14.9 15.5 6.1 6.9 0.5 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat NSF PF02071.20 EGG23458.1 - 7.1 7.9 6.7 1.5e+02 3.9 1.3 4.4 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat Vps55 PF04133.14 EGG23460.1 - 2.7e-29 101.5 1.5 3.2e-29 101.3 1.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Oleosin PF01277.17 EGG23460.1 - 2.8 7.7 4.7 0.81 9.5 0.2 2.2 2 1 1 3 3 3 0 Oleosin SRP1_TIP1 PF00660.17 EGG23461.1 - 0.008 16.2 0.1 0.033 14.3 0.1 1.8 2 0 0 2 2 2 1 Seripauperin and TIP1 family LRR_8 PF13855.6 EGG23461.1 - 0.019 14.7 0.4 0.099 12.4 0.0 2.1 2 0 0 2 2 2 0 Leucine rich repeat ATP-synt_ab PF00006.25 EGG23462.1 - 3.6e-55 186.9 0.0 8.7e-55 185.7 0.0 1.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EGG23462.1 - 2.2e-27 95.3 0.0 8.3e-24 83.8 0.0 2.5 1 1 1 2 2 2 2 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EGG23462.1 - 1.5e-05 25.4 0.0 3.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain MTHFR PF02219.17 EGG23463.1 - 1.4e-120 402.0 0.0 1.7e-120 401.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase La PF05383.17 EGG23463.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 La domain Lipase_3 PF01764.25 EGG23464.1 - 1.5e-06 28.1 0.2 0.00052 19.9 0.1 2.7 2 0 0 2 2 2 2 Lipase (class 3) Zip PF02535.22 EGG23464.1 - 0.0025 17.1 0.2 0.0025 17.1 0.2 3.0 3 0 0 3 3 3 1 ZIP Zinc transporter Pex14_N PF04695.13 EGG23464.1 - 1.9 9.1 12.5 0.88 10.2 0.1 3.6 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LRR_4 PF12799.7 EGG23465.1 - 1.1e-12 47.9 13.3 5.1e-05 23.6 0.4 4.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG23465.1 - 2.8e-12 46.2 11.9 1.9e-08 33.9 5.3 3.5 3 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 EGG23465.1 - 9.4e-06 25.2 1.5 0.0002 20.9 1.1 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 EGG23465.1 - 0.59 10.3 7.3 27 5.1 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich repeat POPLD PF08170.12 EGG23467.1 - 0.13 12.6 0.5 0.17 12.3 0.5 1.3 1 1 0 1 1 1 0 POPLD (NUC188) domain Abhydrolase_1 PF00561.20 EGG23468.1 - 0.00068 19.4 1.2 0.0012 18.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold SET PF00856.28 EGG23469.1 - 1.3e-14 55.0 0.3 3.3e-13 50.4 0.3 2.3 1 1 0 1 1 1 1 SET domain SR-25 PF10500.9 EGG23469.1 - 1.4 8.5 10.4 0.1 12.2 3.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FKBP_C PF00254.28 EGG23470.1 - 1.4e-24 86.2 2.9 2.2e-24 85.6 0.0 2.9 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase WH1 PF00568.23 EGG23470.1 - 0.00035 20.5 0.1 0.00086 19.2 0.1 1.7 1 0 0 1 1 1 1 WH1 domain RRM_1 PF00076.22 EGG23471.1 - 4.8e-14 51.9 0.1 7e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1722 PF08349.11 EGG23472.1 - 0.011 16.0 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) DUF3420 PF11900.8 EGG23472.1 - 0.55 10.4 2.8 26 5.1 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3420) XYPPX PF02162.17 EGG23473.1 - 0.027 14.3 30.2 0.027 14.3 30.2 7.7 2 1 3 5 5 5 0 XYPPX repeat (two copies) Myotub-related PF06602.14 EGG23474.1 - 8.4e-21 74.3 29.5 1.9e-18 66.6 29.5 2.9 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 EGG23474.1 - 4.6e-07 29.7 0.2 1.4e-06 28.1 0.2 1.8 1 0 0 1 1 1 1 GRAM domain LIM PF00412.22 EGG23474.1 - 0.11 12.7 12.2 2.1 8.7 2.3 2.8 2 0 0 2 2 2 0 LIM domain DUF3439 PF11921.8 EGG23474.1 - 2.5 8.1 6.0 7.8 6.5 6.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Prok-RING_1 PF14446.6 EGG23474.1 - 7.2 6.6 10.7 12 5.9 1.0 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 CENP-F_leu_zip PF10473.9 EGG23474.1 - 7.8 6.5 40.4 3.6 7.6 15.0 3.0 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MFS_2 PF13347.6 EGG23475.1 - 1.4e-96 323.6 22.3 1.8e-96 323.4 22.3 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 EGG23475.1 - 6.3e-19 68.1 22.2 6.3e-19 68.1 22.2 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily fn3 PF00041.21 EGG23476.1 - 0.13 12.6 11.4 0.67 10.3 0.1 3.3 4 0 0 4 4 4 0 Fibronectin type III domain Vps26 PF03643.15 EGG23478.1 - 1.6e-43 148.7 0.6 2.3e-43 148.2 0.6 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EGG23478.1 - 0.0097 16.0 0.1 0.029 14.4 0.1 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Sin3a_C PF16879.5 EGG23479.1 - 3.3e-63 214.1 9.4 3.3e-63 214.1 9.4 6.7 6 1 1 7 7 7 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 EGG23479.1 - 2.3e-38 130.2 4.4 3.9e-38 129.5 0.0 3.3 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.21 EGG23479.1 - 1.3e-31 108.4 14.6 1e-15 57.6 5.3 5.7 5 1 0 5 5 5 3 Paired amphipathic helix repeat DUF3439 PF11921.8 EGG23479.1 - 1.3 9.0 4.8 6.9 6.7 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Endotoxin_N PF03945.14 EGG23481.1 - 2.4e-05 24.2 4.7 6.2e-05 22.8 4.7 1.7 1 1 0 1 1 1 1 delta endotoxin, N-terminal domain CIMR PF00878.18 EGG23481.1 - 0.0058 16.7 1.2 0.0058 16.7 1.2 2.1 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat Pkinase PF00069.25 EGG23482.1 - 1.8e-80 270.1 0.0 2.1e-80 269.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23482.1 - 3e-37 128.3 0.0 3.6e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG23482.1 - 4e-06 26.4 0.0 7e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG23482.1 - 7.1e-06 25.5 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGG23482.1 - 0.00047 19.9 0.1 0.087 12.4 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGG23482.1 - 0.00052 18.9 0.0 0.00084 18.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGG23482.1 - 0.0017 18.3 0.0 0.012 15.6 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGG23482.1 - 0.031 13.9 0.2 0.078 12.6 0.1 1.7 1 1 0 1 1 1 0 RIO1 family 5_nucleotid PF05761.14 EGG23482.1 - 0.064 12.2 0.0 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family MFS_1 PF07690.16 EGG23483.1 - 8.3e-55 186.1 50.9 8.9e-51 172.9 28.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG23483.1 - 8e-06 25.0 25.5 2.1e-05 23.6 24.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Fst_toxin PF13955.6 EGG23483.1 - 0.29 11.1 2.2 0.3 11.1 0.1 2.1 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system Glyco_hydro_9 PF00759.19 EGG23484.1 - 1.4e-118 396.9 9.2 2e-118 396.4 9.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Suf PF05843.14 EGG23485.1 - 2e-07 31.3 0.2 2e-07 31.3 0.2 3.6 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EGG23485.1 - 0.00039 20.9 0.0 1.5 9.4 0.0 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGG23485.1 - 0.0041 16.4 0.6 2.3 7.3 0.2 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG23485.1 - 0.011 16.4 0.0 10 7.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat S1 PF00575.23 EGG23485.1 - 0.76 10.2 8.9 8 6.9 0.0 5.0 5 1 0 5 5 5 0 S1 RNA binding domain SET PF00856.28 EGG23486.1 - 8.1e-14 52.4 5.0 2.6e-13 50.7 5.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGG23486.1 - 0.00038 20.5 18.5 0.00038 20.5 18.5 2.8 2 1 0 2 2 2 1 MYND finger SAF PF08666.12 EGG23486.1 - 0.16 12.6 0.0 33 5.2 0.0 2.3 2 0 0 2 2 2 0 SAF domain Toxin_10 PF05431.11 EGG23486.1 - 2.1 7.8 6.7 0.59 9.6 2.2 2.0 2 0 0 2 2 2 0 Insecticidal Crystal Toxin, P42 DUF1084 PF06454.11 EGG23487.1 - 2.6e-16 59.8 17.5 3.7e-16 59.3 17.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF5435 PF17503.2 EGG23487.1 - 0.0096 15.7 0.3 0.029 14.1 0.1 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5435) RRM PF10378.9 EGG23487.1 - 0.043 13.5 1.2 0.091 12.5 1.2 1.6 1 0 0 1 1 1 0 Putative RRM domain Senescence_reg PF04520.13 EGG23488.1 - 0.02 15.8 4.5 0.32 11.8 4.5 2.4 1 1 0 1 1 1 0 Senescence regulator Dynactin PF12455.8 EGG23489.1 - 2.1e-35 122.4 12.0 2.1e-35 122.4 12.0 4.3 3 1 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.25 EGG23489.1 - 7.1e-22 77.2 0.6 1.2e-21 76.5 0.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain Phage_GP20 PF06810.11 EGG23489.1 - 0.00066 19.5 25.1 0.00066 19.5 25.1 7.1 3 2 3 7 7 7 1 Phage minor structural protein GP20 Tox-REase-9 PF15650.6 EGG23489.1 - 0.46 10.8 3.7 4.5 7.6 4.5 2.3 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 9 ILEI PF15711.5 EGG23491.1 - 1.6e-48 163.1 8.9 1.8e-14 53.9 0.0 5.5 5 0 0 5 5 5 5 Interleukin-like EMT inducer PC-Esterase PF13839.6 EGG23491.1 - 0.04 13.7 1.6 0.067 12.9 1.6 1.2 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p ILEI PF15711.5 EGG23492.1 - 2.5e-57 191.3 7.4 3.8e-13 49.7 0.0 5.9 6 0 0 6 6 6 5 Interleukin-like EMT inducer Peptidase_C14 PF00656.22 EGG23492.1 - 3.1e-08 33.9 0.0 9.4e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Caspase domain Laminin_G_3 PF13385.6 EGG23493.1 - 6.1e-13 49.2 0.7 6.1e-13 49.2 0.7 2.7 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 EGG23493.1 - 3.5e-06 27.6 0.0 1.7e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 Laminin G domain Pentaxin PF00354.17 EGG23493.1 - 0.00015 21.6 0.1 0.0004 20.1 0.1 1.7 1 0 0 1 1 1 1 Pentaxin family Laminin_G_1 PF00054.23 EGG23493.1 - 0.00016 21.9 0.0 0.00039 20.6 0.0 1.7 1 0 0 1 1 1 1 Laminin G domain Laminin_G_3 PF13385.6 EGG23494.1 - 2.9e-13 50.2 4.9 2.9e-13 50.2 4.9 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 EGG23494.1 - 1.1e-05 26.0 0.1 2.6e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 EGG23494.1 - 0.0033 17.6 0.1 0.0075 16.5 0.1 1.6 1 0 0 1 1 1 1 Laminin G domain DUF697 PF05128.12 EGG23494.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF697) B_lectin PF01453.24 EGG23495.1 - 0.0049 17.4 0.7 4.9 7.7 0.5 3.7 4 0 0 4 4 4 2 D-mannose binding lectin zf-CCCH_4 PF18044.1 EGG23496.1 - 1.7e-06 27.7 1.0 3.6e-06 26.6 1.0 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGG23496.1 - 1.9e-06 27.7 4.5 3.7e-06 26.8 4.5 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EGG23496.1 - 3.6e-06 26.7 1.9 6.4e-06 25.9 1.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HGTP_anticodon PF03129.20 EGG23496.1 - 0.0019 18.3 0.1 0.0047 17.0 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain Torus PF16131.5 EGG23496.1 - 0.0039 17.9 0.1 0.0039 17.9 0.1 4.8 5 0 0 5 5 5 1 Torus domain zf-CCCH_2 PF14608.6 EGG23496.1 - 0.16 12.5 2.9 0.39 11.3 2.9 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-RanBP PF00641.18 EGG23496.1 - 0.2 11.0 3.5 0.55 9.6 3.5 1.9 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others HECT PF00632.25 EGG23498.1 - 1.4e-79 267.8 0.0 2.4e-79 267.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Kelch_4 PF13418.6 EGG23498.1 - 1.2e-30 105.2 15.1 7.6e-08 32.2 0.4 5.8 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EGG23498.1 - 9.5e-21 73.3 15.8 7.4e-06 26.1 0.1 6.0 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 EGG23498.1 - 1.4e-20 72.8 20.0 4e-07 29.9 0.0 6.7 6 1 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 EGG23498.1 - 6.2e-15 55.1 20.1 6.8e-05 23.1 0.0 6.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 EGG23498.1 - 8.8e-15 54.0 8.9 0.00065 19.2 0.1 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EGG23498.1 - 3.8e-07 29.8 14.7 0.011 15.7 0.1 5.6 5 0 0 5 5 5 3 Kelch motif EGF_2 PF07974.13 EGG23498.1 - 0.024 15.0 14.4 0.056 13.8 14.4 1.6 1 0 0 1 1 1 0 EGF-like domain Fig1 PF12351.8 EGG23498.1 - 1.3 9.0 6.6 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 FERM_N PF09379.10 EGG23499.1 - 0.098 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 FERM N-terminal domain TetR_C_37 PF18665.1 EGG23499.1 - 0.11 13.1 0.2 0.21 12.2 0.2 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zinc_ribbon_2 PF13240.6 EGG23499.1 - 1.2 9.0 6.1 3.8 7.4 6.2 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EGG23499.1 - 2.4 7.7 6.3 2.3 7.8 4.3 2.0 1 1 1 2 2 2 0 zinc-ribbon domain zf-CCCH PF00642.24 EGG23500.1 - 2.7e-11 43.1 14.4 1.5e-06 27.9 2.6 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EGG23500.1 - 2.1e-05 24.2 0.0 6.8e-05 22.6 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EGG23500.1 - 2.4e-05 24.2 12.5 0.00037 20.5 1.0 2.7 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EGG23500.1 - 0.47 11.2 0.2 0.47 11.2 0.2 3.4 3 0 0 3 3 3 0 Torus domain Rhodanese PF00581.20 EGG23501.1 - 9.6e-05 22.9 0.0 0.00025 21.5 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Glyco_transf_20 PF00982.21 EGG23502.1 - 2.5e-123 412.3 0.0 7.8e-123 410.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGG23502.1 - 8.7e-43 146.1 0.0 1.3e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EGG23502.1 - 0.096 12.4 0.6 0.25 11.0 0.3 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 EGG23503.1 - 1.8e-29 102.1 2.4 3.4e-12 46.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG23503.1 - 5.2e-26 90.7 0.8 1.8e-12 47.5 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG23503.1 - 1.9e-23 82.2 1.4 1.1e-08 35.2 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23503.1 - 2.3e-23 79.7 0.2 0.00036 20.7 0.1 5.5 4 1 1 5 5 5 4 Ankyrin repeat Ank PF00023.30 EGG23503.1 - 4.4e-22 77.5 0.4 0.0002 21.7 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat PH PF00169.29 EGG23503.1 - 9.2e-10 39.0 1.2 5.1e-09 36.6 0.2 2.4 2 0 0 2 2 2 1 PH domain WD40 PF00400.32 EGG23504.1 - 0.00054 20.7 15.6 0.49 11.3 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat TPR_2 PF07719.17 EGG23505.1 - 1.3e-16 59.3 4.9 0.001 19.0 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGG23505.1 - 1.4e-13 50.1 9.1 0.001 18.8 0.1 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGG23505.1 - 7.9e-10 38.7 7.1 0.029 15.0 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG23505.1 - 2.1e-09 36.9 1.1 0.23 11.8 0.0 5.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGG23505.1 - 1.5e-08 35.1 2.2 0.034 14.8 0.3 3.9 2 2 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG23505.1 - 1.5e-05 24.6 2.7 0.19 11.5 0.3 4.7 5 0 0 5 5 5 2 TPR repeat TPR_12 PF13424.6 EGG23505.1 - 2.1e-05 24.7 6.9 0.052 13.9 0.3 4.1 4 1 1 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG23505.1 - 9.3e-05 22.6 5.4 0.14 12.4 0.9 3.2 2 2 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EGG23505.1 - 0.00017 22.1 0.2 0.82 10.7 0.0 4.6 5 1 0 5 5 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG23505.1 - 0.00035 20.6 0.1 0.036 14.2 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG23505.1 - 0.0018 18.1 3.7 0.0092 16.0 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGG23505.1 - 0.072 13.0 2.5 0.3 11.0 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGG23505.1 - 0.11 13.0 0.3 39 4.9 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Pyrophosphatase PF00719.19 EGG23505.1 - 0.31 10.8 4.1 3 7.6 1.4 2.5 2 0 0 2 2 2 0 Inorganic pyrophosphatase MIT PF04212.18 EGG23505.1 - 6.2 7.0 14.3 5.4 7.2 0.7 4.3 5 1 1 6 6 5 0 MIT (microtubule interacting and transport) domain Thg1 PF04446.12 EGG23506.1 - 2.5e-33 114.8 0.9 3.1e-33 114.4 0.1 1.6 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EGG23506.1 - 0.025 14.7 1.4 0.071 13.3 0.0 2.3 2 1 0 2 2 2 0 Thg1 C terminal domain PUF PF00806.19 EGG23507.1 - 1e-20 72.2 8.4 0.00015 21.3 0.0 7.5 7 0 0 7 7 7 6 Pumilio-family RNA binding repeat Cnd1_N PF12922.7 EGG23508.1 - 7.6e-32 110.5 0.3 7.6e-32 110.5 0.3 3.9 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 EGG23508.1 - 2.1e-20 73.4 17.2 8.4e-17 61.7 0.4 5.8 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGG23508.1 - 0.002 18.2 2.3 17 6.0 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 EGG23508.1 - 0.0078 16.6 0.0 4.4 7.8 0.0 3.3 3 0 0 3 3 3 1 HEAT repeats Cnd3 PF12719.7 EGG23508.1 - 0.019 14.2 4.2 0.017 14.4 1.4 2.4 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain FANCI_S2 PF14676.6 EGG23508.1 - 0.092 13.1 1.7 8.4 6.7 0.1 3.4 3 0 0 3 3 3 0 FANCI solenoid 2 RTP1_C1 PF10363.9 EGG23508.1 - 0.26 11.5 4.0 1.1 9.5 0.1 3.8 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Iso_dh PF00180.20 EGG23509.1 - 1.6e-103 346.6 0.1 1.8e-103 346.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1084 PF06454.11 EGG23510.1 - 0.0001 21.8 19.9 0.0002 20.8 19.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Peptidase_M1 PF01433.20 EGG23511.1 - 2.8e-73 246.1 2.5 5.4e-73 245.2 2.5 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGG23511.1 - 6.6e-47 160.6 1.3 1e-46 160.0 1.3 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGG23511.1 - 3.5e-36 125.1 0.4 7e-36 124.2 0.4 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Acyl_transf_3 PF01757.22 EGG23512.1 - 1.5e-23 83.4 49.6 1.5e-23 83.4 49.6 1.7 2 0 0 2 2 2 1 Acyltransferase family SWI-SNF_Ssr4 PF08549.10 EGG23513.1 - 0.016 13.9 1.7 0.018 13.7 1.7 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SOG2 PF10428.9 EGG23513.1 - 1.3 8.1 13.2 1.6 7.9 13.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein BioY PF02632.14 EGG23515.1 - 0.0078 16.3 1.7 0.018 15.1 1.7 1.5 1 0 0 1 1 1 1 BioY family UCR_UQCRX_QCR9 PF05365.12 EGG23516.1 - 0.093 12.7 0.2 4.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4974 PF16344.5 EGG23518.1 - 0.13 12.2 1.2 2.1 8.4 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4974) Spt20 PF12090.8 EGG23518.1 - 0.56 9.8 8.9 0.89 9.1 8.9 1.2 1 0 0 1 1 1 0 Spt20 family Myc_N PF01056.18 EGG23520.1 - 0.015 15.2 2.1 0.59 10.0 1.9 2.1 2 0 0 2 2 2 0 Myc amino-terminal region PIEZO PF15917.5 EGG23520.1 - 0.018 14.6 10.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 0 Piezo Spt20 PF12090.8 EGG23520.1 - 5.6 6.5 15.9 9 5.8 15.9 1.3 1 0 0 1 1 1 0 Spt20 family CN_hydrolase PF00795.22 EGG23522.1 - 2.1e-13 50.2 0.0 3.4e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4874 PF16173.5 EGG23522.1 - 0.055 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) PQ-loop PF04193.14 EGG23523.1 - 4.9e-34 115.9 19.8 1.1e-18 66.8 7.1 3.6 3 0 0 3 3 3 2 PQ loop repeat Nop14 PF04147.12 EGG23523.1 - 0.0084 14.4 16.7 0.014 13.7 16.7 1.3 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EGG23523.1 - 0.011 15.2 12.8 0.016 14.6 12.8 1.3 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 EGG23523.1 - 0.028 13.8 7.4 0.045 13.1 7.4 1.3 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 EGG23523.1 - 0.041 13.2 13.9 0.067 12.5 13.9 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EGG23523.1 - 0.082 11.2 12.0 0.14 10.4 12.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 EGG23523.1 - 0.47 9.8 19.4 0.95 8.8 19.4 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Merozoite_SPAM PF07133.11 EGG23523.1 - 0.87 9.6 26.0 2 8.3 26.0 1.6 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) HSP70 PF00012.20 EGG23524.1 - 7.1e-122 407.6 4.8 5.4e-64 216.4 0.7 3.0 1 1 2 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 EGG23524.1 - 1e-11 44.3 0.4 2.9e-08 32.9 0.2 2.3 1 1 1 2 2 2 2 MreB/Mbl protein Actin PF00022.19 EGG23524.1 - 0.058 12.0 0.1 7.7 5.0 0.0 2.1 1 1 1 2 2 2 0 Actin FtsA PF14450.6 EGG23524.1 - 0.079 13.4 0.3 2.7 8.4 0.3 2.7 1 1 0 1 1 1 0 Cell division protein FtsA FHA PF00498.26 EGG23525.1 - 1.6e-09 38.0 0.0 4.2e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain RhoGEF PF00621.20 EGG23527.1 - 1e-29 104.1 5.5 1.3e-29 103.7 5.5 1.1 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 EGG23529.1 - 5.3e-10 39.0 0.0 8.8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain CS PF04969.16 EGG23529.1 - 3.1e-08 34.5 0.0 5.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 CS domain SH3_1 PF00018.28 EGG23529.1 - 3.5e-08 32.9 0.0 7.1e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG23529.1 - 3.4e-06 26.6 0.0 1.8e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Glutaminase PF04960.15 EGG23530.1 - 1.8e-25 89.7 0.0 2.9e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Glutaminase SH3_1 PF00018.28 EGG23530.1 - 4.7e-12 45.3 0.3 8.3e-12 44.5 0.3 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGG23530.1 - 1.6e-08 34.1 0.0 3.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGG23530.1 - 2.2e-08 33.8 0.1 3.7e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Band_7 PF01145.25 EGG23531.1 - 9.5e-07 29.0 1.8 1.2e-06 28.6 0.2 2.0 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7 PF01145.25 EGG23532.1 - 1e-06 28.9 1.0 1e-06 28.9 1.0 1.9 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7 PF01145.25 EGG23533.1 - 8.1e-07 29.2 1.4 1.2e-06 28.7 0.2 1.9 2 1 0 2 2 2 1 SPFH domain / Band 7 family Ras PF00071.22 EGG23534.1 - 3.3e-50 169.8 0.0 4.2e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG23534.1 - 2.9e-23 82.4 0.0 5.7e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG23534.1 - 1.1e-11 44.5 0.0 1.5e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG23534.1 - 1.7e-06 27.7 0.1 1.1e-05 25.1 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG23534.1 - 0.0019 18.2 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MAP65_ASE1 PF03999.12 EGG23534.1 - 0.033 12.9 6.4 0.04 12.6 6.4 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MGC-24 PF05283.11 EGG23534.1 - 0.11 12.9 9.5 0.18 12.2 9.5 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Herpes_capsid PF06112.11 EGG23534.1 - 0.14 12.2 14.1 0.2 11.7 14.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Apt1 PF10351.9 EGG23534.1 - 0.17 10.7 7.9 0.22 10.3 7.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EGG23534.1 - 0.24 9.9 9.4 0.25 9.8 9.4 1.1 1 0 0 1 1 1 0 Macoilin family PduV-EutP PF10662.9 EGG23534.1 - 0.3 10.8 1.5 10 5.9 0.1 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SSP160 PF06933.11 EGG23534.1 - 0.42 8.8 17.8 0.53 8.4 17.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CCDC24 PF15669.5 EGG23534.1 - 0.52 10.2 5.2 0.76 9.6 5.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Alpha_GJ PF03229.13 EGG23534.1 - 2.8 8.5 7.8 5 7.7 7.8 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J Herpes_pp85 PF04637.12 EGG23534.1 - 3.3 6.0 11.8 4.3 5.7 11.8 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4614 PF15391.6 EGG23534.1 - 3.8 7.5 17.2 6.1 6.8 17.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) IBN_N PF03810.19 EGG23535.1 - 0.013 15.4 1.3 0.038 13.9 0.3 2.5 2 0 0 2 2 2 0 Importin-beta N-terminal domain RNA_lig_T4_1 PF09511.10 EGG23536.1 - 1.2e-40 139.7 0.0 1.8e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 RNA ligase RNA_ligase PF09414.10 EGG23536.1 - 0.0019 18.5 0.0 0.023 15.0 0.0 2.2 1 1 0 1 1 1 1 RNA ligase SNAPc_SNAP43 PF09808.9 EGG23536.1 - 0.024 14.6 0.1 0.055 13.4 0.1 1.5 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF1163 PF06651.11 EGG23536.1 - 0.05 13.7 1.7 0.083 13.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1163) adh_short PF00106.25 EGG23537.1 - 1.1e-30 106.6 0.0 1.7e-26 92.9 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG23537.1 - 1.9e-20 73.4 0.0 4.1e-19 69.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG23537.1 - 2.6e-08 34.0 0.0 4.5e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EGG23537.1 - 0.018 15.3 0.0 0.062 13.6 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Raptor_N PF14538.6 EGG23538.1 - 2e-71 238.7 0.0 5.7e-71 237.2 0.0 1.8 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EGG23538.1 - 2.3e-13 50.4 4.5 0.3 12.0 0.0 7.9 7 0 0 7 7 7 3 WD domain, G-beta repeat HEAT PF02985.22 EGG23538.1 - 8.4e-11 41.2 3.0 0.02 15.1 0.1 6.5 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 EGG23538.1 - 1.1e-05 25.5 0.0 0.0016 18.5 0.0 2.9 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGG23538.1 - 6.9e-05 23.2 0.1 0.0051 17.2 0.0 3.2 2 1 2 4 4 4 3 HEAT repeats ANAPC4_WD40 PF12894.7 EGG23538.1 - 0.0071 16.6 0.0 4.9 7.5 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Adaptin_N PF01602.20 EGG23538.1 - 0.012 14.2 0.0 0.019 13.5 0.0 1.3 1 0 0 1 1 1 0 Adaptin N terminal region HEAT_EZ PF13513.6 EGG23538.1 - 0.028 14.9 0.1 3.1 8.4 0.0 3.1 3 0 0 3 3 3 0 HEAT-like repeat TRAM_LAG1_CLN8 PF03798.16 EGG23539.1 - 9.3e-22 77.7 9.0 9.3e-22 77.7 9.0 3.3 2 1 1 3 3 3 1 TLC domain Secretin_N_2 PF07655.13 EGG23539.1 - 2.9 8.5 29.4 0.24 12.0 12.1 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain Mucin PF01456.17 EGG23539.1 - 9.6 6.2 19.3 1.2 9.1 13.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein AA_kinase PF00696.28 EGG23540.1 - 4.8e-25 88.5 0.1 9.3e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 EGG23540.1 - 8.6e-23 81.1 0.0 4.3e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAT PF04768.13 EGG23540.1 - 7.7e-11 41.9 0.9 7.7e-11 41.9 0.9 1.8 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dhC PF02774.18 EGG23540.1 - 6.4e-09 36.1 0.0 2.6e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Sacchrp_dh_NADP PF03435.18 EGG23540.1 - 0.072 13.3 0.0 2.2 8.5 0.0 2.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Kinesin PF00225.23 EGG23541.1 - 1.4e-111 372.6 3.6 1.4e-111 372.6 3.6 3.8 3 1 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EGG23541.1 - 1.6e-26 93.0 1.6 1.6e-26 93.0 1.6 3.3 3 1 0 3 3 3 1 Microtubule binding TA0956 PF11513.8 EGG23541.1 - 0.018 15.3 0.4 0.072 13.3 0.4 2.0 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 GalKase_gal_bdg PF10509.9 EGG23542.1 - 3e-21 74.7 0.0 5.5e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 EGG23542.1 - 1.3e-14 54.3 0.0 5e-14 52.4 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EGG23542.1 - 5.1e-10 39.4 0.4 1.3e-09 38.1 0.4 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain CLU_N PF15044.6 EGG23542.1 - 0.098 13.0 0.0 4.2 7.8 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial function, CLU-N-term Cation_efflux PF01545.21 EGG23543.1 - 9e-33 113.7 0.0 1.3e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Cation efflux family LRR_6 PF13516.6 EGG23543.1 - 9.9e-09 34.6 13.3 0.025 14.6 0.0 5.6 5 0 0 5 5 5 3 Leucine Rich repeat NUDIX PF00293.28 EGG23544.1 - 8.8e-11 42.0 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Connexin PF00029.19 EGG23545.1 - 0.012 15.4 0.9 0.021 14.6 0.9 1.4 1 0 0 1 1 1 0 Connexin DUF1980 PF09323.10 EGG23545.1 - 0.94 9.4 4.9 7.2 6.5 5.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Ctr PF04145.15 EGG23545.1 - 5.2 7.7 7.3 17 6.0 0.0 2.7 2 1 0 2 2 2 0 Ctr copper transporter family COX15-CtaA PF02628.15 EGG23546.1 - 1.3e-109 366.2 7.4 1.7e-109 365.8 7.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein NUDIX_2 PF13869.6 EGG23547.1 - 1.2e-77 259.8 0.1 1.4e-77 259.6 0.1 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.28 EGG23547.1 - 0.0041 17.2 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain TLD PF07534.16 EGG23548.1 - 3.7e-16 59.6 1.5 5.4e-16 59.1 1.5 1.3 1 0 0 1 1 1 1 TLD BTB_2 PF02214.22 EGG23548.1 - 4.1e-09 36.7 0.0 7.7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ELO PF01151.18 EGG23549.1 - 1.2e-62 211.7 17.9 1.4e-62 211.5 17.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ank_5 PF13857.6 EGG23550.1 - 0.0096 16.2 0.1 1.4 9.3 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 EGG23551.1 - 6.6e-12 44.1 0.2 6.9e-05 22.1 0.2 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGG23551.1 - 8e-11 41.0 0.8 2.2e-06 27.1 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGG23551.1 - 6.7e-08 32.9 0.0 8e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGG23551.1 - 2e-07 30.7 0.1 4e-05 23.4 0.0 1.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG23551.1 - 6e-05 22.4 0.2 0.00054 19.3 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 EGG23551.1 - 0.0016 18.7 0.0 0.0021 18.3 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EGG23551.1 - 0.0032 17.8 0.0 0.004 17.5 0.0 1.0 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region DUF563 PF04577.14 EGG23552.1 - 2.7e-26 93.0 0.1 2.1e-25 90.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Glycos_transf_1 PF00534.20 EGG23552.1 - 6.9e-26 90.8 0.0 1.4e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 EGG23552.1 - 1e-19 71.0 0.0 2.6e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_1_4 PF13692.6 EGG23552.1 - 2.9e-19 69.8 0.0 5.8e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_tranf_2_3 PF13641.6 EGG23552.1 - 2.4e-09 37.4 0.0 8.2e-09 35.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EGG23552.1 - 3e-09 36.8 0.0 6.4e-08 32.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_4 PF13439.6 EGG23552.1 - 9.7e-09 35.4 0.0 3.5e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_2_3 PF13632.6 EGG23552.1 - 0.00078 19.4 0.2 0.0046 16.9 0.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_trans_1_2 PF13524.6 EGG23552.1 - 0.0065 16.8 0.0 0.025 15.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_7C PF02709.14 EGG23552.1 - 0.044 13.4 0.6 0.11 12.2 0.6 1.6 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Dot_icm_IcmQ PF09475.10 EGG23552.1 - 0.079 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Acetyltransf_3 PF13302.7 EGG23553.1 - 9.5e-22 78.2 0.0 1.1e-21 77.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG23553.1 - 7.1e-07 29.5 0.0 9.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EGG23553.1 - 2.1e-06 27.5 0.0 3.5e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG23553.1 - 3e-05 23.9 0.0 5.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EGG23553.1 - 9.9e-05 22.5 1.5 0.00011 22.4 0.3 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG23553.1 - 0.021 14.8 0.1 0.042 13.8 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain HsbA PF12296.8 EGG23554.1 - 0.11 13.0 0.9 3.6 8.1 0.1 2.9 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Menin PF05053.13 EGG23556.1 - 0.0066 14.9 7.0 0.0093 14.4 7.0 1.1 1 0 0 1 1 1 1 Menin Radial_spoke PF04712.12 EGG23556.1 - 0.95 8.3 9.0 1.7 7.5 9.0 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein MgtC PF02308.16 EGG23556.1 - 3.8 7.9 14.9 0.18 12.2 4.2 2.5 2 0 0 2 2 2 0 MgtC family CENP-B_dimeris PF09026.10 EGG23556.1 - 4 7.9 20.2 0.99 9.8 14.7 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4484 PF14831.6 EGG23556.1 - 4.9 7.1 11.0 7.8 6.5 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) AAA PF00004.29 EGG23557.1 - 3.2e-37 127.9 0.0 6.5e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGG23557.1 - 1.6e-10 40.6 0.1 3.6e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGG23557.1 - 0.0034 17.5 0.0 0.007 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGG23557.1 - 0.049 13.9 0.0 4.7 7.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 EGG23557.1 - 0.079 13.0 0.1 0.39 10.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EGG23557.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Fra10Ac1 PF09725.9 EGG23558.1 - 1.1e-49 167.7 2.6 2e-49 166.8 2.6 1.5 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 RhoGEF67_u2 PF16614.5 EGG23558.1 - 0.61 10.2 3.6 0.56 10.3 0.9 2.2 2 1 0 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 Spt20 PF12090.8 EGG23559.1 - 0.0027 17.3 26.4 0.0027 17.3 26.4 3.8 2 1 1 3 3 3 1 Spt20 family IP_trans PF02121.18 EGG23560.1 - 1.1e-109 365.8 1.9 1.2e-109 365.6 1.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Suc_Fer-like PF06999.12 EGG23561.1 - 8.7e-35 120.4 0.1 4e-34 118.2 0.0 1.9 2 0 0 2 2 2 1 Sucrase/ferredoxin-like YbgS PF13985.6 EGG23561.1 - 0.0051 17.1 8.0 0.011 16.0 8.0 1.5 1 0 0 1 1 1 1 YbgS-like protein V_ATPase_I PF01496.19 EGG23561.1 - 0.046 11.6 4.3 0.064 11.2 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fer2_2 PF01799.20 EGG23561.1 - 0.075 13.1 0.1 22 5.1 0.0 2.7 2 0 0 2 2 2 0 [2Fe-2S] binding domain Mem_trans PF03547.18 EGG23561.1 - 0.1 11.0 0.7 0.15 10.5 0.7 1.1 1 0 0 1 1 1 0 Membrane transport protein Menin PF05053.13 EGG23561.1 - 0.27 9.5 4.8 0.34 9.2 4.8 1.2 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 EGG23561.1 - 0.43 9.1 8.5 0.51 8.8 8.5 1.1 1 0 0 1 1 1 0 Macoilin family YdjO PF14169.6 EGG23562.1 - 0.053 13.3 0.1 0.077 12.7 0.1 1.3 1 0 0 1 1 1 0 Cold-inducible protein YdjO DUF3581 PF12119.8 EGG23562.1 - 0.058 12.8 0.2 0.067 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) RGM_C PF06534.13 EGG23562.1 - 0.089 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus PIP49_N PF14875.6 EGG23563.1 - 0.42 10.5 5.4 0.87 9.4 0.6 2.6 2 0 0 2 2 2 0 N-term cysteine-rich ER, FAM69 Tmemb_55A PF09788.9 EGG23563.1 - 0.56 9.2 11.6 0.34 10.0 3.2 2.7 2 0 0 2 2 2 0 Transmembrane protein 55A Rhodanese PF00581.20 EGG23564.1 - 1.3e-25 90.0 0.0 2.5e-11 44.0 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain BES1_N PF05687.13 EGG23564.1 - 2.9 8.3 9.3 5.2 7.4 9.3 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Pox_MCEL PF03291.16 EGG23565.1 - 1.3e-27 96.8 2.7 3.7e-18 65.7 0.7 2.1 1 1 0 2 2 2 2 mRNA capping enzyme ADK PF00406.22 EGG23566.1 - 1.4e-49 168.0 0.0 2.3e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGG23566.1 - 1.6e-36 125.8 0.0 2.2e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG23566.1 - 1.3e-08 35.5 0.0 2.2e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGG23566.1 - 1.5e-05 25.1 0.0 4.3e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGG23566.1 - 0.00022 21.0 0.1 0.24 11.1 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.12 EGG23566.1 - 0.0004 19.7 0.1 0.0033 16.7 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 EGG23566.1 - 0.0084 16.5 0.6 0.075 13.4 0.2 2.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 EGG23566.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 EGG23566.1 - 0.03 14.7 0.1 0.059 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGG23566.1 - 0.04 13.1 0.1 0.074 12.2 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain dNK PF01712.19 EGG23566.1 - 0.11 12.3 0.3 0.23 11.3 0.1 1.6 2 0 0 2 2 2 0 Deoxynucleoside kinase Ploopntkinase3 PF18751.1 EGG23566.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Pox_A3L PF05288.11 EGG23567.1 - 0.11 12.6 0.8 0.31 11.0 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A3L Protein Sec7 PF01369.20 EGG23568.1 - 1.7e-34 119.1 0.2 3.6e-34 118.1 0.2 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EGG23568.1 - 2.7e-26 92.4 5.6 2.7e-26 92.4 5.6 4.3 3 1 1 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EGG23568.1 - 1.1e-08 35.0 1.1 1.1e-08 35.0 1.1 3.4 3 1 1 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF4211 PF13926.6 EGG23568.1 - 0.039 14.0 0.1 0.21 11.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) Med20 PF08612.11 EGG23569.1 - 2.2e-22 79.5 1.2 3.2e-22 79.0 1.2 1.2 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex YccV-like PF08755.11 EGG23569.1 - 0.57 10.7 4.7 9 6.9 0.5 2.4 3 0 0 3 3 3 0 Hemimethylated DNA-binding protein YccV like CUE PF02845.16 EGG23570.1 - 1.2e-12 47.3 0.1 2.4e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 CUE domain Alpha-amylase_C PF02806.18 EGG23570.1 - 0.052 14.0 1.1 0.14 12.7 1.1 1.7 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain Activator_LAG-3 PF11498.8 EGG23570.1 - 3 6.7 25.9 4.5 6.1 25.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 NmrA PF05368.13 EGG23572.1 - 5.5e-17 62.1 0.0 6.9e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NOA36 PF06524.12 EGG23573.1 - 0.0096 15.3 17.8 0.011 15.1 17.8 1.1 1 0 0 1 1 1 1 NOA36 protein Cwf_Cwc_15 PF04889.12 EGG23573.1 - 0.28 10.9 19.0 0.4 10.4 19.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SGT1 PF07093.11 EGG23573.1 - 0.57 8.6 13.6 0.65 8.4 13.6 1.0 1 0 0 1 1 1 0 SGT1 protein SpoIIIAH PF12685.7 EGG23573.1 - 1.7 8.4 18.2 2.3 8.0 18.2 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein SDA1 PF05285.12 EGG23573.1 - 4.4 6.6 19.1 5.3 6.4 19.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGG23573.1 - 4.7 5.3 20.4 5.5 5.1 20.4 1.0 1 0 0 1 1 1 0 Nop14-like family Lipase_3 PF01764.25 EGG23574.1 - 3.1e-26 92.0 0.0 4.7e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGG23574.1 - 0.00044 20.9 0.0 0.001 19.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 EGG23574.1 - 0.0072 15.9 0.4 0.081 12.5 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EGG23574.1 - 0.033 13.4 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 EGG23574.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 EGG23574.1 - 0.18 11.5 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Dna2 PF08696.11 EGG23576.1 - 4e-56 190.0 0.1 4e-56 190.0 0.1 3.3 3 0 0 3 3 3 1 DNA replication factor Dna2 AAA_12 PF13087.6 EGG23576.1 - 5.2e-51 173.1 0.6 5.2e-51 173.1 0.6 3.0 2 1 0 2 2 1 1 AAA domain AAA_11 PF13086.6 EGG23576.1 - 9.9e-25 87.8 0.0 6.8e-15 55.6 0.0 5.3 4 2 1 6 6 3 2 AAA domain AAA_30 PF13604.6 EGG23576.1 - 1.2e-10 41.4 0.0 3.1e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG23576.1 - 4.5e-09 36.8 0.1 1.4e-07 31.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EGG23576.1 - 3.3e-06 27.0 0.0 0.86 9.3 0.0 4.1 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EGG23576.1 - 0.00022 21.2 0.1 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 1 Helicase T2SSE PF00437.20 EGG23576.1 - 0.0028 16.8 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 EGG23576.1 - 0.0036 16.8 0.2 0.011 15.2 0.2 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_17 PF13207.6 EGG23576.1 - 0.018 15.5 0.3 0.12 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EGG23576.1 - 0.021 14.5 0.2 0.045 13.4 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EGG23576.1 - 0.037 14.2 0.1 0.12 12.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 EGG23576.1 - 0.051 14.0 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EGG23576.1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGG23576.1 - 0.083 13.2 0.3 0.75 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGG23576.1 - 0.13 12.8 0.0 0.13 12.8 0.0 4.3 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 EGG23576.1 - 0.15 12.5 0.6 0.49 10.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGG23576.1 - 0.15 12.0 1.0 0.45 10.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) LRR_6 PF13516.6 EGG23577.1 - 0.015 15.3 0.5 0.2 11.8 0.1 2.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 EGG23577.1 - 0.019 15.4 1.0 0.044 14.2 0.3 2.0 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGG23577.1 - 0.024 15.1 0.6 0.31 11.7 0.1 2.5 2 0 0 2 2 2 0 Leucine Rich Repeat Cobl PF09469.10 EGG23577.1 - 0.085 13.1 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain fn3 PF00041.21 EGG23578.1 - 3.5e-14 52.9 15.0 0.00019 21.7 0.7 5.7 5 0 0 5 5 5 4 Fibronectin type III domain EGF_2 PF07974.13 EGG23578.1 - 0.00025 21.3 8.1 0.00081 19.7 8.1 1.9 1 0 0 1 1 1 1 EGF-like domain Pur_ac_phosph_N PF16656.5 EGG23578.1 - 0.0062 17.1 15.8 0.22 12.1 0.3 5.4 4 1 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 EGG23578.1 - 0.015 15.6 9.2 2.2 8.6 0.5 4.7 4 1 0 4 4 4 0 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 EGG23578.1 - 0.017 15.5 12.6 1.8 9.0 0.2 5.2 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) EB PF01683.18 EGG23578.1 - 0.042 14.1 5.5 0.23 11.8 5.5 2.4 1 0 0 1 1 1 0 EB module EGF PF00008.27 EGG23578.1 - 6.1 7.3 8.8 3 8.2 5.4 2.4 2 0 0 2 2 2 0 EGF-like domain Tim17 PF02466.19 EGG23579.1 - 1.5e-26 92.9 6.4 2.3e-26 92.4 6.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.6 EGG23579.1 - 0.072 12.8 6.8 5.6 6.8 0.0 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 EGG23579.1 - 0.086 12.9 12.6 1.4 8.9 0.3 2.2 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.6 EGG23579.1 - 4.6 7.1 14.9 2.8 7.8 1.2 2.3 2 0 0 2 2 2 0 Glycine-zipper domain Spatacsin_C PF14649.6 EGG23580.1 - 4.7e-99 331.3 8.1 1.8e-98 329.4 8.1 2.1 1 0 0 1 1 1 1 Spatacsin C-terminus Pox_Ag35 PF03286.14 EGG23580.1 - 1.4 8.7 12.4 0.37 10.5 8.1 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Amastin PF07344.11 EGG23581.1 - 0.00031 20.6 2.3 0.0007 19.5 1.7 2.0 1 1 0 1 1 1 1 Amastin surface glycoprotein Fig1 PF12351.8 EGG23581.1 - 0.032 14.2 1.3 0.032 14.2 1.3 2.3 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 CAAD PF14159.6 EGG23581.1 - 0.041 13.7 1.0 0.041 13.7 1.0 2.3 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase MARVEL PF01284.23 EGG23581.1 - 0.069 13.2 9.5 2.3 8.3 3.9 2.7 1 1 2 3 3 3 0 Membrane-associating domain ODV-E18 PF10717.9 EGG23581.1 - 0.15 12.0 0.4 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 OPT PF03169.15 EGG23581.1 - 0.21 10.2 6.6 1.2 7.7 0.1 2.2 2 1 0 2 2 2 0 OPT oligopeptide transporter protein Sigma_reg_N PF13800.6 EGG23581.1 - 0.27 11.6 3.2 10 6.5 0.2 3.0 3 0 0 3 3 3 0 Sigma factor regulator N-terminal HIG_1_N PF04588.13 EGG23581.1 - 0.57 10.5 2.5 5.9 7.2 0.0 2.7 2 0 0 2 2 2 0 Hypoxia induced protein conserved region DUF4175 PF13779.6 EGG23581.1 - 0.89 7.4 1.4 1.2 7.0 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SUR7 PF06687.12 EGG23581.1 - 3.7 7.1 13.4 0.22 11.1 6.2 2.4 1 1 1 2 2 2 0 SUR7/PalI family DHHC PF01529.20 EGG23581.1 - 5.1 7.2 6.3 11 6.2 5.3 2.1 2 1 0 2 2 2 0 DHHC palmitoyltransferase TPPK_C PF12555.8 EGG23581.1 - 8.1 6.6 13.2 0.28 11.2 1.8 3.1 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal GGDEF PF00990.21 EGG23582.1 - 2.1e-25 89.4 1.5 5e-25 88.1 1.5 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Ank_2 PF12796.7 EGG23583.1 - 1.5e-21 76.8 6.2 2.8e-09 37.4 0.3 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG23583.1 - 4.7e-11 42.7 0.4 0.0025 18.1 0.1 4.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23583.1 - 3e-10 39.4 5.3 0.98 10.2 0.0 7.3 6 2 2 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 EGG23583.1 - 1.2e-09 38.5 4.8 2.4e-05 24.8 0.2 4.1 2 2 4 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EGG23583.1 - 0.00037 20.8 3.5 30 5.3 0.0 6.4 5 1 3 8 8 8 0 Ankyrin repeat DUF5049 PF16468.5 EGG23583.1 - 0.00044 20.1 0.1 4 7.4 0.0 4.2 3 2 2 5 5 5 2 Domain of unknown function (DUF5049) Ca_bind_SSO6904 PF18249.1 EGG23583.1 - 0.0023 18.3 0.1 0.0057 17.0 0.1 1.7 1 0 0 1 1 1 1 Calcium binding protein SSO6904 FAM195 PF14799.6 EGG23583.1 - 0.022 15.1 0.3 0.084 13.2 0.0 2.1 3 0 0 3 3 3 0 FAM195 family Baculo_LEF-11 PF06385.12 EGG23583.1 - 0.027 15.0 6.0 2.4 8.7 0.0 3.2 4 0 0 4 4 4 0 Baculovirus LEF-11 protein GGDEF PF00990.21 EGG23584.1 - 1.3e-35 122.6 0.9 2.1e-35 121.9 0.9 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Guanylate_cyc PF00211.20 EGG23584.1 - 0.0015 18.2 0.8 0.0027 17.3 0.1 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Rap_GAP PF02145.15 EGG23585.1 - 8.1e-18 64.6 0.1 1.2e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 Rap/ran-GAP UQ_con PF00179.26 EGG23586.1 - 7.9e-38 129.3 0.0 1.1e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IP_trans PF02121.18 EGG23587.1 - 1.7e-97 325.8 4.7 3.2e-97 324.9 4.7 1.4 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein T2SSF PF00482.23 EGG23588.1 - 0.77 9.7 0.0 0.77 9.7 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF2207 PF09972.9 EGG23588.1 - 5.9 5.5 7.0 10 4.7 7.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Methyltransf_2 PF00891.18 EGG23589.1 - 1.4e-34 119.2 0.0 1.9e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGG23589.1 - 0.00016 21.6 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain TrmB PF01978.19 EGG23589.1 - 0.031 14.2 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Adeno_E1B_19K PF01691.16 EGG23589.1 - 0.036 13.6 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen Methyltransf_12 PF08242.12 EGG23589.1 - 0.056 14.2 0.0 0.94 10.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Rrf2 PF02082.20 EGG23589.1 - 0.074 13.4 0.1 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator HTH_AraC PF00165.23 EGG23589.1 - 0.098 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family zf-AN1 PF01428.16 EGG23590.1 - 2e-18 66.3 39.2 4.6e-11 42.7 10.8 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger UBX PF00789.20 EGG23590.1 - 1.3e-12 47.8 0.0 5e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 UBX domain DUF3682 PF12446.8 EGG23590.1 - 0.47 10.9 4.3 0.84 10.1 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF1154 PF06631.11 EGG23590.1 - 1.5 8.9 5.0 16 5.6 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) Piezo_RRas_bdg PF12166.8 EGG23591.1 - 7.9e-100 335.1 8.7 1.1e-99 334.6 0.0 2.7 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain CH PF00307.31 EGG23591.1 - 9.6e-19 67.6 0.1 9.6e-19 67.6 0.1 3.3 4 0 0 4 4 4 1 Calponin homology (CH) domain ETRAMP PF09716.10 EGG23591.1 - 0.059 13.4 0.1 6.8 6.8 0.0 4.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Ala_racemase_N PF01168.20 EGG23592.1 - 1.6e-18 67.2 0.0 2.1e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 EGG23592.1 - 2.7e-17 63.2 0.3 9e-17 61.5 0.0 2.0 3 0 0 3 3 3 1 Putative serine dehydratase domain zf-CRD PF17979.1 EGG23593.1 - 5.3e-35 120.9 6.2 5.3e-35 120.9 6.2 2.9 2 1 1 3 3 3 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 EGG23593.1 - 7.1e-16 58.3 1.0 2.3e-15 56.7 1.0 2.0 1 0 0 1 1 1 1 FHA domain zf-C3HC4_3 PF13920.6 EGG23593.1 - 5.2e-07 29.4 13.2 5.2e-07 29.4 13.2 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 EGG23593.1 - 1.2e-06 28.8 0.2 3.6e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-CCHH PF10283.9 EGG23593.1 - 7.8e-06 25.8 5.0 2.5e-05 24.2 5.0 2.0 1 0 0 1 1 1 1 PBZ domain zf-RING_2 PF13639.6 EGG23593.1 - 5e-05 23.5 16.8 5e-05 23.5 16.8 3.6 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG23593.1 - 8.7e-05 22.3 16.6 8.7e-05 22.3 16.6 3.8 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EGG23593.1 - 0.00095 19.0 6.1 0.00095 19.0 6.1 2.7 3 1 1 4 4 4 1 zf-RING of BARD1-type protein FHA_2 PF17913.1 EGG23593.1 - 0.0029 17.8 0.0 0.0071 16.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-C3HC4 PF00097.25 EGG23593.1 - 0.0035 17.2 17.3 0.0035 17.2 17.3 4.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Med13_C PF06333.12 EGG23593.1 - 2.5 7.3 14.6 4.3 6.5 14.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain UBX PF00789.20 EGG23594.1 - 8.9e-12 45.1 0.0 1.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain FKBP_C PF00254.28 EGG23595.1 - 2.8e-17 62.8 0.0 5.1e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 EGG23595.1 - 3.2e-09 36.2 3.4 0.06 13.2 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG23595.1 - 5.3e-08 32.4 1.2 0.0007 19.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG23595.1 - 3.5e-06 26.8 3.4 0.0021 18.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGG23595.1 - 0.05 12.8 0.0 0.089 12.0 0.0 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG23595.1 - 0.17 12.8 0.0 2.5 9.2 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Abhydro_lipase PF04083.16 EGG23596.1 - 1.1e-16 60.1 0.0 4.8e-16 58.1 0.0 2.0 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGG23596.1 - 1.3e-11 44.6 0.4 2e-08 34.2 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG23596.1 - 3.1e-06 26.6 0.0 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 XPC-binding PF09280.11 EGG23596.1 - 0.18 11.6 0.2 0.56 10.0 0.0 1.9 2 0 0 2 2 2 0 XPC-binding domain WD40 PF00400.32 EGG23598.1 - 1.3e-20 73.3 9.7 0.0012 19.6 0.0 7.9 7 0 0 7 7 7 4 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 EGG23598.1 - 2.1e-11 43.4 10.8 4.5e-11 42.4 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ANAPC4_WD40 PF12894.7 EGG23598.1 - 2.2e-09 37.5 3.2 0.25 11.6 0.0 5.4 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4 PF00097.25 EGG23598.1 - 2e-08 33.9 12.2 6.3e-08 32.4 12.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG23598.1 - 5.4e-08 32.7 10.3 2.5e-07 30.6 6.1 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGG23598.1 - 1.2e-07 31.8 11.9 8.3e-07 29.1 5.0 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGG23598.1 - 5.1e-07 29.9 10.4 1.3e-06 28.6 10.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGG23598.1 - 5.3e-07 29.4 7.5 5.3e-07 29.4 7.5 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 EGG23598.1 - 1.8e-06 28.0 0.1 7.5e-06 26.0 0.1 2.2 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.6 EGG23598.1 - 2e-06 27.6 10.8 6.3e-06 26.1 10.8 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGG23598.1 - 0.00019 21.2 9.7 0.002 18.0 10.1 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGG23598.1 - 0.00048 20.2 3.7 0.0013 18.8 3.7 1.8 1 0 0 1 1 1 1 zinc RING finger of MSL2 SPX PF03105.19 EGG23598.1 - 0.0023 17.9 20.0 0.0023 17.9 20.0 2.3 2 0 0 2 2 2 1 SPX domain zf-Nse PF11789.8 EGG23598.1 - 0.0023 17.7 7.8 0.0066 16.2 7.8 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 EGG23598.1 - 0.0097 15.8 3.0 0.018 14.9 3.0 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EGG23598.1 - 0.64 10.3 15.2 0.031 14.6 8.4 2.4 2 1 0 2 2 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGG23598.1 - 1.4 8.7 11.6 2 8.2 8.1 2.6 2 0 0 2 2 2 0 RING-like zinc finger CHDCT2 PF08074.11 EGG23598.1 - 5.5 7.1 7.6 7.4 6.7 5.7 2.2 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain Methyltransf_25 PF13649.6 EGG23599.1 - 1.1e-08 35.6 0.0 2.8e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGG23599.1 - 6.3e-07 29.0 0.1 3.8e-06 26.5 0.0 2.0 1 1 1 2 2 2 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 EGG23599.1 - 1.2e-06 28.5 0.0 2e-05 24.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG23599.1 - 2e-06 27.7 0.0 4.2e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG23599.1 - 1.6e-05 25.5 0.0 5.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG23599.1 - 0.0024 18.6 0.1 0.01 16.6 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EGG23599.1 - 0.0082 15.8 0.0 0.095 12.3 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 EGG23599.1 - 0.04 13.2 0.1 0.28 10.4 0.0 2.2 3 0 0 3 3 3 0 Mycolic acid cyclopropane synthetase PCI PF01399.27 EGG23600.1 - 1.3e-11 44.9 0.2 1.3e-11 44.9 0.2 3.1 3 1 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 EGG23600.1 - 5.4e-10 38.8 2.4 1.4e-09 37.4 2.4 1.8 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix DASH_Duo1 PF08651.10 EGG23600.1 - 0.017 14.9 2.1 0.13 12.1 0.2 3.0 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF3486 PF11985.8 EGG23600.1 - 0.2 12.1 2.5 0.15 12.4 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) DUF3385 PF11865.8 EGG23600.1 - 0.24 11.3 6.3 0.71 9.8 1.7 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) Chlam_PMP PF02415.17 EGG23601.1 - 0.0011 19.2 48.5 0.22 12.1 0.6 10.5 11 0 0 11 11 11 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Insulin_TMD PF17870.1 EGG23601.1 - 1.6 8.9 9.3 0.2 11.7 0.2 2.8 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment SLC35F PF06027.12 EGG23602.1 - 3.4e-93 312.5 28.1 4.2e-93 312.1 28.1 1.1 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EGG23602.1 - 6.4e-10 39.3 38.1 4.1e-07 30.3 12.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 EGG23602.1 - 2.5e-09 36.5 11.8 2.5e-09 36.5 11.8 1.7 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 EGG23602.1 - 0.0035 16.6 21.5 0.0081 15.4 21.5 1.6 1 1 0 1 1 1 1 UAA transporter family adh_short_C2 PF13561.6 EGG23603.1 - 1.6e-67 227.5 0.1 2e-67 227.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGG23603.1 - 4.1e-54 183.0 0.7 4.9e-54 182.8 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGG23603.1 - 4.8e-09 36.4 0.3 7.1e-09 35.8 0.3 1.3 1 0 0 1 1 1 1 KR domain AAA_31 PF13614.6 EGG23603.1 - 0.00025 21.0 1.4 0.00043 20.3 0.5 1.8 2 0 0 2 2 2 1 AAA domain AdoHcyase_NAD PF00670.21 EGG23603.1 - 0.023 14.8 1.6 0.041 13.9 1.3 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EGG23603.1 - 0.049 13.2 0.2 0.081 12.5 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain THF_DHG_CYH_C PF02882.19 EGG23603.1 - 0.05 12.9 0.3 0.11 11.8 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF5507 PF17612.2 EGG23603.1 - 0.09 12.5 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5507) NAD_binding_7 PF13241.6 EGG23603.1 - 0.14 12.6 0.2 0.42 11.1 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Ran_BP1 PF00638.18 EGG23604.1 - 1.2e-40 138.6 0.1 2.1e-40 137.8 0.1 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EGG23604.1 - 0.014 15.3 0.7 0.02 14.8 0.0 1.6 2 0 0 2 2 2 0 WH1 domain Voldacs PF03517.13 EGG23604.1 - 0.22 11.6 7.6 0.035 14.2 3.3 1.8 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling NupH_GANP PF16768.5 EGG23604.1 - 2.2 7.9 9.3 0.1 12.3 2.1 1.9 2 0 0 2 2 2 0 Nucleoporin homology of Germinal-centre associated nuclear protein RhoGEF PF00621.20 EGG23605.1 - 1.1e-46 159.4 4.4 1.1e-46 159.4 4.4 2.4 3 0 0 3 3 3 1 RhoGEF domain AAA_2 PF07724.14 EGG23605.1 - 6.7e-41 140.2 0.9 2.9e-32 112.1 0.5 3.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGG23605.1 - 6.6e-13 49.2 5.0 2.3e-05 24.8 0.1 4.2 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGG23605.1 - 6.4e-06 26.2 0.1 0.00016 21.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGG23605.1 - 0.00023 20.6 0.1 0.0071 15.8 0.2 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ClpB_D2-small PF10431.9 EGG23605.1 - 0.00042 20.3 0.3 0.00042 20.3 0.3 3.0 3 0 0 3 3 3 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 EGG23605.1 - 0.0026 18.1 0.0 0.014 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGG23605.1 - 0.0055 17.1 0.0 0.031 14.7 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain Sigma54_activat PF00158.26 EGG23605.1 - 0.0064 16.2 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 EGG23605.1 - 0.01 15.6 0.2 0.11 12.3 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain KdgM PF06178.13 EGG23605.1 - 0.021 14.4 0.2 0.067 12.8 0.2 1.8 1 0 0 1 1 1 0 Oligogalacturonate-specific porin protein (KdgM) SPATA19 PF15212.6 EGG23605.1 - 0.032 14.4 0.1 0.13 12.5 0.1 2.0 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial DUF3439 PF11921.8 EGG23605.1 - 0.069 13.1 2.5 0.23 11.4 2.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AAA_18 PF13238.6 EGG23605.1 - 0.074 13.6 1.8 0.13 12.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGG23605.1 - 0.076 13.3 0.1 0.41 10.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain WBP-1 PF11669.8 EGG23605.1 - 0.098 13.3 0.6 0.43 11.2 0.6 2.2 1 0 0 1 1 1 0 WW domain-binding protein 1 V_ATPase_I PF01496.19 EGG23606.1 - 0.00097 17.2 12.5 0.0012 16.9 12.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family APG6_N PF17675.1 EGG23606.1 - 0.014 15.9 10.1 0.014 15.9 10.1 1.6 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4385 PF14328.6 EGG23606.1 - 0.041 13.9 0.1 0.085 12.9 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4385) PDDEXK_10 PF07788.11 EGG23606.1 - 0.19 11.7 5.3 0.57 10.1 0.7 2.4 1 1 1 2 2 2 0 PD-(D/E)XK nuclease superfamily PEARLI-4 PF05278.12 EGG23606.1 - 0.6 9.7 12.3 0.079 12.5 6.8 1.8 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Phage_GPO PF05929.11 EGG23606.1 - 0.82 9.2 6.7 1.4 8.5 6.7 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RCC1 PF00415.18 EGG23607.1 - 1.5e-42 144.0 4.2 2.7e-10 40.7 0.0 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG23607.1 - 6.7e-24 83.1 16.2 2.4e-08 33.6 0.0 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat bZIP_1 PF00170.21 EGG23608.1 - 8.7e-10 38.6 7.0 8.7e-10 38.6 7.0 2.4 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGG23608.1 - 4.5e-05 23.4 3.9 4.5e-05 23.4 3.9 2.4 2 0 0 2 2 2 1 Basic region leucine zipper TEX13 PF15186.6 EGG23608.1 - 0.15 11.8 3.1 0.27 10.9 3.1 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Pkinase PF00069.25 EGG23609.1 - 1.1e-60 205.2 0.1 1.6e-55 188.4 0.1 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23609.1 - 5.2e-30 104.6 0.0 2.6e-29 102.3 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase PH_3 PF14593.6 EGG23609.1 - 1.8e-23 82.6 0.8 7.1e-23 80.7 0.3 2.3 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 EGG23609.1 - 0.0009 18.6 1.5 0.088 12.1 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 EGG23609.1 - 0.0058 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG23609.1 - 0.047 13.6 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rap_GAP PF02145.15 EGG23610.1 - 2.1e-58 196.9 0.0 5.3e-58 195.6 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP GGDEF PF00990.21 EGG23611.1 - 3e-29 101.9 0.5 5.6e-29 101.0 0.5 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Guanylate_cyc PF00211.20 EGG23611.1 - 0.0041 16.8 0.1 0.0072 16.0 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ank_2 PF12796.7 EGG23612.1 - 7.8e-30 103.3 17.6 3.2e-09 37.3 0.3 4.7 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG23612.1 - 6.5e-14 51.8 2.2 0.0095 16.2 0.1 6.2 1 1 4 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG23612.1 - 3.1e-12 46.8 8.4 2.8e-05 24.6 0.2 5.1 2 2 5 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23612.1 - 3.7e-12 45.3 5.1 1.1 10.1 0.0 8.7 8 1 1 9 9 9 2 Ankyrin repeat DUF5049 PF16468.5 EGG23612.1 - 3.6e-05 23.6 0.1 4.4 7.3 0.0 5.1 4 2 2 6 6 6 2 Domain of unknown function (DUF5049) Ank PF00023.30 EGG23612.1 - 8.1e-05 22.9 4.4 23 5.7 0.0 7.1 4 1 2 6 6 6 0 Ankyrin repeat Ca_bind_SSO6904 PF18249.1 EGG23612.1 - 0.0038 17.5 0.1 0.011 16.1 0.1 1.8 1 0 0 1 1 1 1 Calcium binding protein SSO6904 FAM195 PF14799.6 EGG23612.1 - 0.019 15.3 0.2 0.14 12.6 0.1 2.5 1 1 1 2 2 2 0 FAM195 family TRAPP PF04051.16 EGG23612.1 - 0.028 14.2 0.1 0.48 10.1 0.1 2.7 1 1 0 1 1 1 0 Transport protein particle (TRAPP) component Xpo1 PF08389.12 EGG23612.1 - 0.05 13.7 0.9 0.92 9.6 0.4 2.7 2 1 0 2 2 2 0 Exportin 1-like protein Pkinase PF00069.25 EGG23614.1 - 3.3e-72 243.0 0.0 3.3e-72 243.0 0.0 4.0 3 1 1 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23614.1 - 3.2e-34 118.4 0.0 3.2e-34 118.4 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGG23614.1 - 7.4 6.4 10.0 3.3 7.6 0.0 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Strumpellin PF10266.9 EGG23615.1 - 0 1512.1 24.1 0 1511.9 24.1 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin Herpes_UL92 PF03048.14 EGG23616.1 - 0.05 13.4 4.4 0.12 12.1 1.4 2.1 1 1 1 2 2 2 0 UL92 family Phage_Mu_Gam PF07352.12 EGG23616.1 - 0.59 10.0 15.3 1.5 8.7 10.0 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Tho2 PF11262.8 EGG23616.1 - 3.3 6.8 13.6 0.51 9.5 8.4 1.8 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 MRPL52 PF18699.1 EGG23616.1 - 4.3 7.6 15.8 2.5 8.4 2.7 2.3 1 1 1 2 2 2 0 Mitoribosomal protein mL52 CENP-H PF05837.12 EGG23616.1 - 7 7.1 12.0 15 6.1 5.3 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ADH_zinc_N_2 PF13602.6 EGG23617.1 - 7.2e-19 69.2 0.0 1.4e-18 68.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGG23617.1 - 4.4e-14 52.6 0.0 7.2e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG23617.1 - 1.9e-10 40.6 0.4 6e-10 39.0 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Orn_Arg_deC_N PF02784.16 EGG23618.1 - 1.7e-39 135.7 0.0 2.2e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGG23618.1 - 1.8e-11 44.1 0.0 2.6e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SeleniumBinding PF11524.8 EGG23618.1 - 0.12 12.8 0.5 0.36 11.3 0.1 2.0 2 0 0 2 2 2 0 Selenium binding protein Cullin_binding PF03556.15 EGG23619.1 - 9.1e-27 93.9 1.2 1.4e-26 93.3 1.2 1.3 1 0 0 1 1 1 1 Cullin binding Macoilin PF09726.9 EGG23619.1 - 0.026 13.1 6.8 0.029 12.9 6.8 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 EGG23619.1 - 0.11 11.2 5.1 0.11 11.1 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ORC6 PF05460.13 EGG23619.1 - 0.14 11.4 11.0 0.24 10.6 11.0 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Presenilin PF01080.17 EGG23619.1 - 0.46 9.2 4.4 0.58 8.9 4.4 1.2 1 0 0 1 1 1 0 Presenilin Dicty_REP PF05086.12 EGG23619.1 - 1.1 7.1 7.1 1.3 6.9 7.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pneumo_att_G PF05539.11 EGG23619.1 - 6.6 6.2 20.9 8.7 5.8 20.9 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G HMA PF00403.26 EGG23620.1 - 6.2e-11 42.6 1.3 8.2e-11 42.2 1.3 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 EGG23620.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain DUF1677 PF07911.13 EGG23620.1 - 0.068 13.6 0.0 0.074 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) zf-RING_5 PF14634.6 EGG23621.1 - 0.0066 16.4 10.1 0.0066 16.4 10.1 2.6 2 0 0 2 2 2 1 zinc-RING finger domain ABC_tran PF00005.27 EGG23621.1 - 0.16 12.5 0.0 0.16 12.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PRK PF00485.18 EGG23621.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EGG23621.1 - 0.22 11.9 0.0 0.55 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain zf-RING_UBOX PF13445.6 EGG23621.1 - 1.2 9.2 12.1 0.19 11.8 6.4 2.7 2 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG23621.1 - 2.2 8.2 19.2 0.022 14.6 10.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AAA_18 PF13238.6 EGG23621.1 - 4.7 7.8 11.5 57 4.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain DIRP PF06584.13 EGG23622.1 - 0.0017 18.5 0.2 0.0035 17.5 0.2 1.5 1 0 0 1 1 1 1 DIRP AAA_17 PF13207.6 EGG23622.1 - 0.082 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SpoU_methylase PF00588.19 EGG23623.1 - 4.2e-24 85.3 0.0 9.6e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family Post_transc_reg PF13797.6 EGG23623.1 - 0.034 14.0 0.2 3.6 7.5 0.1 3.5 3 0 0 3 3 3 0 Post-transcriptional regulator NLRC4_HD PF17889.1 EGG23623.1 - 0.16 12.3 4.3 13 6.2 0.6 3.7 2 0 0 2 2 2 0 NLRC4 helical domain Ribosomal_S26e PF01283.19 EGG23624.1 - 1.9e-49 166.6 6.9 2.2e-49 166.4 6.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 EGG23624.1 - 0.071 13.7 3.3 1 10.0 3.8 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain zf-C3HC PF07967.13 EGG23625.1 - 1e-30 106.5 0.1 1e-30 106.5 0.1 3.1 3 0 0 3 3 3 1 C3HC zinc finger-like Rsm1 PF08600.10 EGG23625.1 - 5.2e-15 55.4 12.4 2.8e-07 30.6 0.1 4.6 3 1 1 4 4 4 3 Rsm1-like BIR PF00653.21 EGG23625.1 - 7.2 7.3 14.0 5 7.8 0.3 3.5 3 1 1 4 4 4 0 Inhibitor of Apoptosis domain NosD PF05048.13 EGG23626.1 - 0.066 12.5 2.2 0.073 12.3 2.2 1.1 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DUF4711 PF15829.5 EGG23627.1 - 0.061 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) zf-LITAF-like PF10601.9 EGG23627.1 - 8.4 6.7 7.0 0.84 9.9 0.1 2.9 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain BTB PF00651.31 EGG23629.1 - 2.7e-23 82.3 0.0 2.9e-22 79.0 0.1 2.6 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 EGG23629.1 - 1.6e-06 28.1 1.9 0.00088 19.3 0.1 4.1 4 0 0 4 4 4 1 BTB And C-terminal Kelch DUF4834 PF16118.5 EGG23629.1 - 0.043 14.8 21.5 0.79 10.7 0.7 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Pro-MCH PF05824.12 EGG23629.1 - 0.25 11.3 8.1 2.5 8.1 0.3 3.1 2 1 1 3 3 3 0 Pro-melanin-concentrating hormone (Pro-MCH) Homeobox_KN PF05920.11 EGG23630.1 - 5.3e-15 55.0 0.1 1.1e-14 54.0 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EGG23630.1 - 0.0047 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Homeodomain BORCS6 PF10157.9 EGG23630.1 - 4.9 7.4 7.5 0.53 10.5 0.2 2.9 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 6 ZapB PF06005.12 EGG23631.1 - 2.3 8.7 10.1 0.14 12.7 4.2 2.0 2 1 0 2 2 2 0 Cell division protein ZapB ANAPC_CDC26 PF10471.9 EGG23631.1 - 4.3 8.2 7.1 3 8.7 2.1 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 SET PF00856.28 EGG23632.1 - 9.1e-17 62.0 0.5 9.1e-17 62.0 0.5 4.6 4 2 0 4 4 4 1 SET domain PHD PF00628.29 EGG23632.1 - 1.4e-16 60.1 28.8 2.9e-08 33.5 5.7 3.9 2 1 1 3 3 3 3 PHD-finger FYRN PF05964.14 EGG23632.1 - 2.1e-15 56.3 0.0 8.5e-15 54.3 0.0 2.2 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-HC5HC2H PF13771.6 EGG23632.1 - 1.6e-10 41.1 5.7 1.6e-10 41.1 5.7 4.7 3 2 1 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EGG23632.1 - 2.4e-10 40.6 7.1 2.4e-10 40.6 7.1 3.9 3 1 1 4 4 4 1 PHD-zinc-finger like domain PHD_2 PF13831.6 EGG23632.1 - 7.2e-10 38.3 9.9 3.4e-07 29.7 0.5 2.9 2 0 0 2 2 2 2 PHD-finger FYRC PF05965.14 EGG23632.1 - 8.4e-08 32.3 0.0 2.8e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus HSP70 PF00012.20 EGG23634.1 - 8.4e-261 866.4 10.3 9.6e-261 866.2 10.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGG23634.1 - 2.1e-15 56.4 0.1 8.1e-14 51.2 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 EGG23634.1 - 0.0035 16.7 0.1 0.0096 15.2 0.1 1.8 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase FGGY_C PF02782.16 EGG23634.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EGG23634.1 - 0.022 13.8 2.5 0.038 13.0 0.1 2.4 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain DUF1894 PF08979.11 EGG23634.1 - 0.035 14.5 0.0 7.6 7.0 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1894) DIOX_N PF14226.6 EGG23634.1 - 0.11 13.3 1.5 0.27 12.0 0.9 1.9 1 1 1 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal CENP-X PF09415.10 EGG23634.1 - 0.16 12.3 1.6 0.52 10.7 1.6 2.0 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Membralin PF09746.9 EGG23634.1 - 2.1 7.3 4.7 4.4 6.2 4.7 1.5 1 0 0 1 1 1 0 Tumour-associated protein PMM PF03332.13 EGG23635.1 - 1.2e-100 335.9 0.2 1.4e-100 335.6 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EGG23635.1 - 7.1e-05 22.7 0.0 0.0004 20.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGG23635.1 - 0.0049 17.2 0.0 0.0081 16.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RPAP1_C PF08620.10 EGG23637.1 - 0.1 12.7 0.0 0.37 10.9 0.0 1.9 1 0 0 1 1 1 0 RPAP1-like, C-terminal DUF4642 PF15484.6 EGG23637.1 - 1.1 9.5 5.8 0.099 12.9 0.6 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4642) DUF3439 PF11921.8 EGG23637.1 - 3.4 7.6 7.9 12 5.9 7.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MMR_HSR1 PF01926.23 EGG23639.1 - 3e-07 30.5 0.9 3.1e-06 27.2 0.6 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGG23639.1 - 1.2e-05 24.7 3.1 1.2e-05 24.7 3.1 2.9 2 1 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 EGG23639.1 - 0.0011 18.9 0.1 0.0011 18.9 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 EGG23639.1 - 0.0017 17.5 1.1 0.0029 16.7 0.1 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein IIGP PF05049.13 EGG23639.1 - 0.0017 17.5 1.0 0.0041 16.2 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 EGG23639.1 - 0.0021 17.8 0.2 0.007 16.1 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 EGG23639.1 - 0.0029 17.3 0.2 0.0087 15.7 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 EGG23639.1 - 0.0042 16.5 0.5 0.009 15.4 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 EGG23639.1 - 0.0049 17.0 12.4 0.25 11.4 0.2 3.6 3 1 0 4 4 3 2 Dynamin family AAA_7 PF12775.7 EGG23639.1 - 0.0068 15.9 0.8 0.035 13.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Septin PF00735.18 EGG23639.1 - 0.0091 15.3 0.1 0.0091 15.3 0.1 2.1 3 0 0 3 3 3 1 Septin GTP_EFTU PF00009.27 EGG23639.1 - 0.01 15.4 0.7 0.028 13.9 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EGG23639.1 - 0.017 15.4 0.1 0.069 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGG23639.1 - 0.019 15.4 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 EGG23639.1 - 0.03 14.1 0.0 0.11 12.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGG23639.1 - 0.045 14.3 4.7 0.049 14.1 0.9 2.6 2 1 0 2 2 2 0 ABC transporter ResIII PF04851.15 EGG23639.1 - 0.092 12.7 0.2 0.092 12.7 0.2 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NACHT PF05729.12 EGG23639.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Sec2p PF06428.11 EGG23639.1 - 0.12 12.4 2.9 0.17 11.9 1.8 1.9 2 0 0 2 2 1 0 GDP/GTP exchange factor Sec2p SMC_N PF02463.19 EGG23639.1 - 0.13 11.7 0.9 0.28 10.6 0.5 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ATP_bind_1 PF03029.17 EGG23639.1 - 0.15 11.8 4.2 0.12 12.1 0.8 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein SMC_Nse1 PF07574.13 EGG23639.1 - 0.23 11.3 2.7 0.81 9.5 1.5 2.3 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex DUF87 PF01935.17 EGG23639.1 - 0.23 11.5 0.1 0.23 11.5 0.1 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain ATPase PF06745.13 EGG23639.1 - 0.43 9.9 5.3 0.14 11.5 0.8 2.3 2 1 0 2 2 2 0 KaiC AAA_23 PF13476.6 EGG23639.1 - 2.5 8.6 15.9 2.8e+02 1.9 15.9 2.4 1 1 0 1 1 1 0 AAA domain YlbD_coat PF14071.6 EGG23639.1 - 2.6 8.3 7.5 0.34 11.2 1.0 2.4 2 1 0 2 2 2 0 Putative coat protein DUF3967 PF13152.6 EGG23639.1 - 5.8 6.8 6.0 23 4.9 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3967) AIG1 PF04548.16 EGG23640.1 - 1.6e-07 30.9 0.1 2.8e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.23 EGG23640.1 - 1.8e-07 31.2 0.0 5.8e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGG23640.1 - 0.00013 22.1 0.0 0.42 10.6 0.0 2.1 2 0 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 EGG23640.1 - 0.00057 19.8 0.0 0.0068 16.3 0.0 2.2 1 1 1 2 2 2 1 RsgA GTPase Septin PF00735.18 EGG23640.1 - 0.016 14.5 0.0 0.089 12.1 0.0 2.0 2 1 0 2 2 2 0 Septin AAA_29 PF13555.6 EGG23640.1 - 0.037 13.8 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGG23640.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Na_Ca_ex PF01699.24 EGG23641.1 - 2.6e-16 59.9 32.6 3e-12 46.8 12.3 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YukC PF10140.9 EGG23641.1 - 0.00096 18.1 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC DUF4956 PF16316.5 EGG23641.1 - 0.057 13.1 2.6 0.16 11.6 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) Pilus_CpaD PF09476.10 EGG23641.1 - 0.14 11.8 0.2 0.31 10.7 0.2 1.5 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF2681 PF10883.8 EGG23641.1 - 0.33 11.4 0.0 0.33 11.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Methyltransf_28 PF02636.17 EGG23643.1 - 8.6e-36 123.9 0.3 8.6e-36 123.9 0.3 2.8 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 EGG23643.1 - 0.027 14.2 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EGG23643.1 - 0.095 13.5 0.4 1.7 9.5 0.0 3.2 2 0 0 2 2 2 0 Methyltransferase domain SLT PF01464.20 EGG23644.1 - 1.9e-05 24.3 0.0 4.8e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Transglycosylase SLT domain Collagen PF01391.18 EGG23644.1 - 6.8e-05 22.5 55.3 0.00027 20.6 21.5 3.5 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Lys PF00062.20 EGG23644.1 - 0.00019 21.7 3.6 0.028 14.7 0.1 2.2 1 1 1 2 2 2 2 C-type lysozyme/alpha-lactalbumin family Glyco_transf_41 PF13844.6 EGG23645.1 - 2.3e-51 174.7 6.0 9.8e-29 100.1 0.0 2.8 3 1 0 3 3 3 2 Glycosyl transferase family 41 TPR_19 PF14559.6 EGG23645.1 - 0.00015 22.2 0.1 0.0039 17.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 EGG23645.1 - 0.049 14.0 0.0 0.66 10.3 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGG23645.1 - 0.096 13.4 0.0 0.68 10.6 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGG23645.1 - 0.13 12.0 0.6 0.23 11.1 0.6 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Esterase_phd PF10503.9 EGG23646.1 - 1.1e-08 34.8 1.1 1.8e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 Esterase PHB depolymerase Dsl1_N PF11988.8 EGG23646.1 - 0.095 11.7 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal Abhydrolase_1 PF00561.20 EGG23651.1 - 1.5e-19 70.6 0.0 7e-19 68.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG23651.1 - 2.3e-13 51.3 0.1 4.1e-13 50.4 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG23651.1 - 1.2e-10 41.1 0.0 2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 EGG23651.1 - 0.12 11.6 0.0 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PARP PF00644.20 EGG23652.1 - 1.6e-29 102.9 1.4 1.2e-28 100.0 0.1 2.9 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGG23652.1 - 7.5e-13 48.8 0.8 1.5e-12 47.8 0.8 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain BRCT_2 PF16589.5 EGG23652.1 - 5.1e-07 30.0 0.2 1.4e-06 28.6 0.2 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGG23652.1 - 6.5e-05 23.2 0.1 0.00021 21.6 0.1 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3439 PF11921.8 EGG23652.1 - 1.1 9.2 5.4 2.4 8.1 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) T6SS_HCP PF05638.12 EGG23653.1 - 2.9e-12 47.1 0.1 5.5e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp GBP PF02263.19 EGG23654.1 - 1.8e-46 158.5 0.0 1.8e-46 158.5 0.0 2.0 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGG23654.1 - 3.1e-05 23.6 21.1 3.1e-05 23.6 21.1 2.2 2 1 0 2 2 2 1 Guanylate-binding protein, C-terminal domain CREPT PF16566.5 EGG23654.1 - 0.095 12.9 10.4 0.25 11.5 9.4 2.3 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4854 PF16146.5 EGG23654.1 - 2.1 8.7 13.9 0.28 11.5 8.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) DUF1515 PF07439.11 EGG23654.1 - 9.8 6.2 6.1 5.9 7.0 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Pilin_N PF07790.11 EGG23655.1 - 0.039 14.9 0.1 0.072 14.0 0.1 1.3 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal zf-C3HC4_3 PF13920.6 EGG23656.1 - 7.5e-11 41.7 8.7 1.2e-10 41.1 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG23656.1 - 3.1e-05 23.7 9.6 5.8e-05 22.9 9.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGG23656.1 - 9.4e-05 22.3 9.2 0.0002 21.3 9.3 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGG23656.1 - 0.00011 22.0 9.4 0.0002 21.2 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG23656.1 - 0.001 19.4 11.0 0.002 18.4 11.0 1.5 1 0 0 1 1 1 1 Ring finger domain DUF3039 PF11238.8 EGG23656.1 - 0.003 17.3 1.2 0.0056 16.4 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3039) Rib_hydrolayse PF02267.17 EGG23656.1 - 0.023 14.1 1.2 0.035 13.5 1.2 1.3 1 0 0 1 1 1 0 ADP-ribosyl cyclase zf-RING_4 PF14570.6 EGG23656.1 - 0.029 14.2 7.2 0.07 12.9 7.2 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Bcr-Abl_Oligo PF09036.10 EGG23656.1 - 0.033 14.2 0.4 0.057 13.4 0.4 1.3 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain zf-P11 PF03854.14 EGG23656.1 - 0.048 13.3 3.5 0.11 12.2 3.5 1.6 1 0 0 1 1 1 0 P-11 zinc finger UPF0242 PF06785.11 EGG23656.1 - 0.064 13.3 0.3 0.09 12.9 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-C3HC4_2 PF13923.6 EGG23656.1 - 0.084 12.7 9.9 0.18 11.7 9.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fer2_3 PF13085.6 EGG23656.1 - 0.091 12.8 1.9 0.16 12.0 1.9 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Prefoldin_2 PF01920.20 EGG23656.1 - 0.12 12.3 1.0 0.19 11.7 1.0 1.2 1 0 0 1 1 1 0 Prefoldin subunit THOC7 PF05615.13 EGG23656.1 - 0.23 11.7 3.2 0.36 11.1 3.2 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 ArfGap PF01412.18 EGG23656.1 - 0.29 11.2 3.8 0.48 10.5 3.8 1.3 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf zf-RING_UBOX PF13445.6 EGG23656.1 - 1 9.4 7.7 0.31 11.1 4.7 1.7 1 1 1 2 2 2 0 RING-type zinc-finger zf-B_box PF00643.24 EGG23656.1 - 3.3 7.9 7.1 7.8 6.7 4.3 2.2 2 0 0 2 2 2 0 B-box zinc finger PI3_PI4_kinase PF00454.27 EGG23657.1 - 5e-44 151.0 0.1 2.5e-43 148.7 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EGG23657.1 - 2.3e-31 109.3 6.2 7.3e-31 107.6 6.2 2.0 1 0 0 1 1 1 1 FAT domain UME PF08064.13 EGG23657.1 - 1.4e-20 73.1 1.8 7.5e-20 70.8 0.2 3.3 4 0 0 4 4 4 1 UME (NUC010) domain FATC PF02260.20 EGG23657.1 - 5.7e-15 54.8 0.0 1.3e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 FATC domain Connexin PF00029.19 EGG23657.1 - 0.033 14.0 1.1 0.075 12.8 1.1 1.6 1 0 0 1 1 1 0 Connexin ANAPC3 PF12895.7 EGG23657.1 - 0.038 14.2 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 HEAT PF02985.22 EGG23657.1 - 0.093 13.0 0.0 2.7 8.5 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat CobT PF06213.12 EGG23657.1 - 0.23 10.8 8.2 0.45 9.9 8.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 EGG23657.1 - 4.1 6.1 17.6 7.4 5.2 0.3 2.6 2 0 0 2 2 2 0 Presenilin Auts2 PF15336.6 EGG23657.1 - 7.7 6.6 7.9 1.4 9.0 4.1 1.6 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein AOX PF01786.17 EGG23658.1 - 2.6e-73 246.2 1.3 3.6e-73 245.7 1.3 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 EGG23658.1 - 0.0011 18.8 0.3 0.0019 18.0 0.3 1.3 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 ubiquitin PF00240.23 EGG23659.1 - 1.5e-09 37.4 0.0 1e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_4 PF18036.1 EGG23659.1 - 2.6e-05 24.2 0.1 0.4 10.7 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin-like domain Rad60-SLD PF11976.8 EGG23659.1 - 8.7e-05 22.3 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGG23659.1 - 0.1 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Methyltransf_2 PF00891.18 EGG23660.1 - 8.6e-35 119.9 0.0 1.2e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGG23660.1 - 0.033 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_12 PF08242.12 EGG23660.1 - 0.046 14.5 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain HTH_20 PF12840.7 EGG23660.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain NAP PF00956.18 EGG23661.1 - 3.5e-07 29.7 10.8 1.8e-06 27.3 6.9 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) AOX PF01786.17 EGG23662.1 - 4.6e-74 248.6 1.0 6.2e-74 248.2 1.0 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 EGG23662.1 - 0.0026 17.6 0.3 0.0047 16.7 0.3 1.4 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 HD PF01966.22 EGG23663.1 - 7.2e-15 55.3 0.1 1.9e-14 53.9 0.1 1.7 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 EGG23663.1 - 0.0021 17.9 1.5 0.0032 17.2 0.3 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase VP4_helical PF17478.2 EGG23663.1 - 0.0094 15.4 0.1 0.024 14.1 0.1 1.6 1 0 0 1 1 1 1 Rotavirus VP4 helical domain DUF2076 PF09849.9 EGG23664.1 - 1.8e-06 28.2 2.7 2.1e-06 28.0 2.7 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EGG23664.1 - 0.0005 20.1 2.0 0.00073 19.6 2.0 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 EGG23664.1 - 0.01 16.1 0.4 0.016 15.5 0.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF2613 PF11021.8 EGG23664.1 - 4.4 7.5 9.6 0.24 11.5 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2613) Acetyltransf_10 PF13673.7 EGG23665.1 - 3.2e-05 23.9 0.0 4.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG23665.1 - 9.7e-05 22.6 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG23665.1 - 0.00099 19.5 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CAP PF00188.26 EGG23666.1 - 0.0035 18.2 4.6 0.41 11.5 0.0 2.3 1 1 1 2 2 2 2 Cysteine-rich secretory protein family Adeno_E3_14_5 PF04834.12 EGG23666.1 - 0.025 15.1 0.3 0.055 14.0 0.3 1.6 1 0 0 1 1 1 0 Early E3 14.5 kDa protein Adaptin_N PF01602.20 EGG23667.1 - 2.8e-113 379.3 22.9 3.6e-113 378.9 22.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EGG23667.1 - 2.3e-50 170.7 1.3 4.7e-50 169.6 1.3 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EGG23667.1 - 3.8e-25 88.3 0.0 1.4e-24 86.5 0.0 2.0 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform Cnd1 PF12717.7 EGG23667.1 - 4.4e-19 69.1 15.3 5.9e-10 39.4 2.6 4.6 2 1 2 4 4 4 4 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGG23667.1 - 2.9e-17 62.8 0.2 2.1e-07 31.2 0.0 5.4 3 1 0 4 4 4 3 HEAT repeats HEAT PF02985.22 EGG23667.1 - 0.00095 19.2 5.1 4.3 7.9 0.0 5.4 8 0 0 8 8 8 2 HEAT repeat BLI1 PF17324.2 EGG23667.1 - 1.1 9.9 4.5 5.2 7.8 0.0 3.7 3 0 0 3 3 3 0 BLOC-1 interactor 1 RRN3 PF05327.11 EGG23668.1 - 5.7e-47 160.5 40.1 3.3e-37 128.3 4.7 4.1 3 1 0 3 3 3 2 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.13 EGG23668.1 - 0.0017 18.4 12.2 0.0024 17.9 12.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Rbx_binding PF18113.1 EGG23668.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain LCE6A PF15858.5 EGG23668.1 - 2.2 9.1 6.6 4.5 8.1 6.6 1.5 1 0 0 1 1 1 0 Late cornified envelope protein 6A family CDC45 PF02724.14 EGG23668.1 - 3.9 5.6 14.0 6 5.0 14.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribonuc_red_lgC PF02867.15 EGG23669.1 - 2.4e-189 630.2 0.0 3.1e-189 629.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGG23669.1 - 7.9e-21 73.9 0.2 2.9e-20 72.1 0.0 2.1 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGG23669.1 - 1.9e-10 41.2 0.1 8.3e-09 35.9 0.1 2.8 1 1 0 1 1 1 1 ATP cone domain SAP130_C PF16014.5 EGG23669.1 - 0.062 12.4 0.0 0.062 12.4 0.0 1.8 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus GTP_EFTU PF00009.27 EGG23670.1 - 2.8e-54 183.6 0.2 3.6e-54 183.3 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGG23670.1 - 2.4e-22 79.4 0.1 7.9e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGG23670.1 - 2.6e-15 56.5 3.9 5.9e-15 55.4 3.9 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGG23670.1 - 1.7e-05 24.9 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGG23670.1 - 0.065 13.0 0.2 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SNF2_N PF00176.23 EGG23672.1 - 3.5e-52 177.3 0.1 3.5e-52 177.3 0.1 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG23672.1 - 5.9e-10 39.5 1.9 1.6e-09 38.1 0.6 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Hint PF01079.20 EGG23672.1 - 0.082 12.4 0.3 0.18 11.3 0.3 1.6 1 0 0 1 1 1 0 Hint module Ank_2 PF12796.7 EGG23673.1 - 3e-12 47.0 4.7 0.00011 22.7 0.1 6.8 4 2 0 6 6 6 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG23673.1 - 2.3e-08 33.7 4.6 6 7.8 0.0 8.6 9 0 0 9 9 9 1 Ankyrin repeat Ank_4 PF13637.6 EGG23673.1 - 1.9e-07 31.5 0.8 0.015 15.9 0.0 6.2 7 0 0 7 7 7 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG23673.1 - 5.1e-06 26.7 0.2 70 3.9 0.1 7.5 7 1 1 8 8 8 0 Ankyrin repeats (many copies) Utp12 PF04003.12 EGG23673.1 - 0.12 12.7 0.8 3.8 7.9 0.4 2.9 2 0 0 2 2 2 0 Dip2/Utp12 Family RNF111_N PF15303.6 EGG23674.1 - 0.00047 20.0 4.7 0.00047 20.0 4.7 1.7 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase Arkadia N-terminus DUF2722 PF10846.8 EGG23674.1 - 0.00094 18.2 1.8 0.00094 18.2 1.8 2.8 3 1 1 4 4 4 1 Protein of unknown function (DUF2722) FAIM1 PF06905.13 EGG23674.1 - 0.11 12.3 2.5 0.45 10.2 1.5 2.2 2 0 0 2 2 2 0 Fas apoptotic inhibitory molecule (FAIM1) CIAPIN1 PF05093.13 EGG23674.1 - 0.39 11.3 4.1 4 8.0 0.3 2.5 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_2 PF00891.18 EGG23675.1 - 1.5e-32 112.6 0.0 2.3e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGG23675.1 - 0.00015 21.6 0.1 0.00027 20.8 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain ASPRs PF17641.2 EGG23675.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Ancylostoma-associated secreted protein related Rrf2 PF02082.20 EGG23675.1 - 0.047 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Pkinase PF00069.25 EGG23676.1 - 2.5e-59 200.8 0.0 6.3e-59 199.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23676.1 - 9.2e-25 87.4 0.3 8.6e-18 64.5 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGG23676.1 - 0.0025 17.2 0.4 0.14 11.4 0.0 2.7 3 0 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.11 EGG23676.1 - 0.019 14.1 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 EGG23676.1 - 0.045 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGG23676.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family CX9C PF16860.5 EGG23677.1 - 1.3e-08 34.7 9.5 0.00019 21.4 0.4 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EGG23677.1 - 3.3e-06 27.1 7.0 0.0005 20.1 0.6 3.8 2 2 2 4 4 4 2 CHCH domain NDUF_B7 PF05676.13 EGG23677.1 - 2.4 7.9 7.8 4.1 7.2 1.7 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EGG23677.1 - 3.3 7.8 13.4 1.5 8.9 5.6 2.4 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like EGF_2 PF07974.13 EGG23678.1 - 0.0019 18.6 16.4 0.0042 17.4 16.4 1.6 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 EGG23678.1 - 2.6 8.4 10.5 5.6 7.4 10.5 1.6 1 0 0 1 1 1 0 EGF-like domain Plasmod_Pvs28 PF06247.11 EGG23678.1 - 7.4 7.0 9.7 21 5.5 9.7 1.8 1 0 0 1 1 1 0 Pvs28 EGF domain 7tm_7 PF08395.12 EGG23681.1 - 0.014 14.6 0.3 0.024 13.8 0.3 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor Orai-1 PF07856.12 EGG23681.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity Glycophorin_A PF01102.18 EGG23681.1 - 0.15 12.3 4.8 0.5 10.6 0.2 2.6 2 1 0 2 2 2 0 Glycophorin A Ank_4 PF13637.6 EGG23684.1 - 5e-07 30.1 3.0 1.3 9.7 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG23684.1 - 9.6e-05 22.9 1.1 0.096 13.3 0.0 4.9 5 1 2 7 7 7 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG23684.1 - 0.0013 19.0 5.5 7.6 7.5 0.0 6.4 8 0 0 8 8 8 1 Ankyrin repeat DUF2496 PF10689.9 EGG23684.1 - 0.22 11.3 0.4 0.61 9.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2496) Dor1 PF04124.12 EGG23685.1 - 2.7e-74 249.9 6.4 5.5e-74 248.9 6.4 1.5 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 EGG23685.1 - 1.6e-07 30.9 7.7 2.7e-07 30.2 7.7 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Exo84_C PF16528.5 EGG23685.1 - 2.2e-07 30.9 0.3 6e-07 29.5 0.3 1.8 1 0 0 1 1 1 1 Exocyst component 84 C-terminal RNase_PH PF01138.21 EGG23686.1 - 2.6e-34 118.6 0.2 4.9e-34 117.7 0.1 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGG23686.1 - 0.034 14.2 0.1 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Fe-ADH PF00465.19 EGG23687.1 - 2.5 6.8 4.4 2.2 7.0 0.0 2.1 1 1 1 2 2 2 0 Iron-containing alcohol dehydrogenase CPL PF08144.11 EGG23688.1 - 9.5e-18 64.9 5.1 6.7e-15 55.7 0.1 4.7 4 1 0 4 4 4 1 CPL (NUC119) domain PUF PF00806.19 EGG23688.1 - 0.00036 20.0 5.1 4.1 7.3 0.0 6.0 7 0 0 7 7 7 2 Pumilio-family RNA binding repeat Bac_rhamnosid6H PF17389.2 EGG23688.1 - 0.033 13.4 0.0 0.086 12.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bcl-2 PF00452.19 EGG23688.1 - 0.084 13.6 0.0 1.6 9.5 0.0 3.0 2 1 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family RPN2_C PF18004.1 EGG23688.1 - 0.95 9.4 14.7 2.2 8.2 14.7 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PRCC PF10253.9 EGG23689.1 - 0.036 14.9 12.7 0.25 12.1 1.9 2.3 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting YlbD_coat PF14071.6 EGG23689.1 - 0.14 12.4 7.8 3 8.1 0.4 3.2 2 0 0 2 2 2 0 Putative coat protein IMUP PF15761.5 EGG23689.1 - 1.6 9.5 5.6 4 8.2 5.6 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein PHP PF02811.19 EGG23690.1 - 2e-07 31.5 0.0 3.1e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 PHP domain DUF1764 PF08576.10 EGG23692.1 - 2.7e-23 82.7 8.9 2.7e-23 82.7 8.9 2.6 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) DUF2457 PF10446.9 EGG23692.1 - 0.00041 19.6 7.0 0.00051 19.3 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC27 PF09507.10 EGG23692.1 - 0.052 12.9 23.2 0.065 12.6 23.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SprA-related PF12118.8 EGG23692.1 - 0.14 11.3 16.4 0.17 11.0 16.4 1.1 1 0 0 1 1 1 0 SprA-related family Hamartin PF04388.12 EGG23692.1 - 1.4 7.5 17.9 1.6 7.3 17.9 1.0 1 0 0 1 1 1 0 Hamartin protein HNF-1_N PF04814.13 EGG23692.1 - 1.6 9.3 16.2 3.4 8.2 16.2 1.6 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Ndc1_Nup PF09531.10 EGG23692.1 - 2.6 6.6 16.0 3 6.4 16.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PA26 PF04636.13 EGG23692.1 - 2.7 6.8 7.5 3 6.7 7.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FSA_C PF10479.9 EGG23692.1 - 5.1 5.1 16.7 6.2 4.8 16.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3886 PF13025.6 EGG23692.1 - 5.5 7.3 16.5 0.86 9.8 12.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Dicty_REP PF05086.12 EGG23692.1 - 6 4.7 18.7 7.9 4.3 18.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Thioredoxin PF00085.20 EGG23693.1 - 8.1e-36 122.1 0.3 3.8e-26 91.1 0.1 3.5 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 EGG23693.1 - 1.4e-15 57.7 2.6 7.6e-05 22.7 0.1 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EGG23693.1 - 1.1e-09 38.6 0.2 0.0024 18.3 0.1 3.7 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGG23693.1 - 2.5e-06 27.7 0.2 0.74 10.2 0.0 4.2 3 2 1 4 4 4 3 Thioredoxin-like OST3_OST6 PF04756.13 EGG23693.1 - 1.8e-05 24.2 3.1 0.0008 18.8 0.0 2.6 2 1 0 3 3 3 2 OST3 / OST6 family, transporter family TraF PF13728.6 EGG23693.1 - 0.1 12.4 2.8 0.74 9.6 0.0 3.0 3 0 0 3 3 3 0 F plasmid transfer operon protein DDE_Tnp_1_2 PF13586.6 EGG23693.1 - 0.43 11.0 1.0 0.62 10.5 0.0 1.8 2 0 0 2 2 2 0 Transposase DDE domain Thiolase_N PF00108.23 EGG23694.1 - 1.7e-89 299.6 0.2 3e-89 298.8 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGG23694.1 - 6.3e-44 148.6 0.8 2.5e-43 146.7 0.5 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain IBR PF01485.21 EGG23694.1 - 1.9e-08 34.4 32.0 2e-05 24.7 11.2 3.8 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EGG23694.1 - 1.7e-06 28.2 5.1 1.7e-06 28.2 5.1 3.0 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG23694.1 - 5.1e-05 23.2 5.8 5.1e-05 23.2 5.8 3.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG23694.1 - 5.6e-05 22.9 5.4 5.6e-05 22.9 5.4 3.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ketoacyl-synt PF00109.26 EGG23694.1 - 0.0001 22.0 0.4 0.0015 18.2 0.4 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain zf-RING_5 PF14634.6 EGG23694.1 - 0.00019 21.3 7.6 0.00019 21.3 7.6 3.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGG23694.1 - 0.0011 18.7 8.0 0.0052 16.5 8.0 2.3 1 0 0 1 1 1 1 RING-like zinc finger TAP_C PF03943.13 EGG23694.1 - 0.022 14.4 0.7 0.67 9.6 0.8 2.5 2 0 0 2 2 2 0 TAP C-terminal domain DUF840 PF05801.11 EGG23694.1 - 0.091 12.8 0.3 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) Mad3_BUB1_I PF08311.12 EGG23694.1 - 0.15 12.0 6.1 2.1 8.4 1.3 2.9 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 NUT PF12881.7 EGG23694.1 - 0.18 10.2 1.9 0.28 9.6 1.9 1.1 1 0 0 1 1 1 0 NUT protein RhoGAP PF00620.27 EGG23695.1 - 6.6e-30 103.9 0.1 2.6e-29 102.0 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain Cobl PF09469.10 EGG23695.1 - 0.13 12.6 0.9 16 5.8 0.0 3.5 2 1 1 3 3 3 0 Cordon-bleu ubiquitin-like domain Citrate_synt PF00285.21 EGG23696.1 - 6.5e-136 453.1 0.0 8.4e-136 452.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Dicty_REP PF05086.12 EGG23696.1 - 4.1 5.2 6.7 6.1 4.7 6.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 EGG23696.1 - 5.4 7.0 13.9 11 6.1 13.9 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein CorA PF01544.18 EGG23697.1 - 0.00017 21.0 11.4 0.00063 19.1 11.4 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PPV_E1_C PF00519.17 EGG23697.1 - 0.086 11.7 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AMP-binding PF00501.28 EGG23698.1 - 1.1e-37 129.7 0.1 9.5e-25 87.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EGG23698.1 - 3.5e-21 76.0 0.0 1e-20 74.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGG23698.1 - 5.5e-20 71.0 1.3 8.8e-20 70.4 1.3 1.3 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Ank_4 PF13637.6 EGG23699.1 - 6.7e-16 58.4 1.6 2.1e-08 34.5 0.0 4.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG23699.1 - 1e-13 51.7 0.8 1.1e-05 25.9 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG23699.1 - 1.3e-09 38.1 4.9 0.18 12.2 0.0 6.6 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23699.1 - 3.5e-08 33.1 0.2 19 6.2 0.0 6.9 7 0 0 7 7 7 1 Ankyrin repeat zinc_ribbon_10 PF10058.9 EGG23700.1 - 3.3e-18 65.1 0.3 6.9e-18 64.1 0.3 1.6 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein EMC3_TMCO1 PF01956.16 EGG23700.1 - 0.017 14.9 0.1 0.033 13.9 0.1 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like UPF0220 PF05255.11 EGG23701.1 - 0.015 14.9 2.2 0.056 13.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) Ctr PF04145.15 EGG23701.1 - 4.8 7.8 7.1 2.9 8.5 3.8 2.4 2 1 0 2 2 2 0 Ctr copper transporter family GATase PF00117.28 EGG23702.1 - 1.5e-36 125.9 0.0 3.1e-36 125.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 EGG23702.1 - 1.2e-19 70.1 0.3 7.4e-12 45.2 0.0 3.3 2 1 0 2 2 2 2 GMP synthase C terminal domain Peptidase_C26 PF07722.13 EGG23702.1 - 2.9e-14 53.4 0.0 5.8e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 EGG23702.1 - 5.1e-09 35.6 0.1 2.3e-06 26.9 0.2 2.2 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 EGG23702.1 - 2.4e-06 27.2 0.1 0.0001 21.9 0.1 2.3 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 EGG23702.1 - 6.1e-05 22.7 0.0 0.00023 20.8 0.1 2.0 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 EGG23702.1 - 0.00042 19.2 0.1 0.0031 16.3 0.1 2.0 2 0 0 2 2 2 1 tRNA methyl transferase Arginosuc_synth PF00764.19 EGG23702.1 - 0.00063 19.1 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase GATase_3 PF07685.14 EGG23702.1 - 0.025 14.2 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ATP_bind_3 PF01171.20 EGG23702.1 - 0.057 13.2 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 PP-loop family Asn_synthase PF00733.21 EGG23702.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase WD40 PF00400.32 EGG23703.1 - 3.8e-28 97.2 17.6 1.9e-07 31.7 0.2 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.12 EGG23703.1 - 8.3e-19 68.7 22.0 8.3e-19 68.7 22.0 3.0 2 1 0 2 2 2 1 Striatin family ANAPC4_WD40 PF12894.7 EGG23703.1 - 6.5e-06 26.4 0.1 1 9.7 0.0 4.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGG23703.1 - 0.00048 20.1 0.0 2.3 8.3 0.0 3.5 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region SAP30_Sin3_bdg PF13867.6 EGG23703.1 - 0.79 10.1 4.4 0.17 12.2 0.3 2.1 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 CK2S PF15011.6 EGG23704.1 - 2.3e-10 40.6 5.0 0.0002 21.3 1.1 2.2 2 0 0 2 2 2 2 Casein Kinase 2 substrate DNA_pol_B_palm PF14792.6 EGG23704.1 - 0.011 16.0 0.5 0.027 14.7 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase beta palm FAA_hydro_N_2 PF18288.1 EGG23704.1 - 0.036 14.5 1.7 0.82 10.1 0.0 2.7 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 ATP-grasp_4 PF13535.6 EGG23704.1 - 0.072 12.7 0.2 0.16 11.5 0.2 1.6 1 0 0 1 1 1 0 ATP-grasp domain RPA_interact_N PF14766.6 EGG23705.1 - 0.0019 17.8 0.4 0.0043 16.7 0.4 1.5 1 0 0 1 1 1 1 Replication protein A interacting N-terminal MCM PF00493.23 EGG23705.1 - 0.059 12.5 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain FAM176 PF14851.6 EGG23705.1 - 0.38 10.4 5.6 0.75 9.5 5.6 1.4 1 0 0 1 1 1 0 FAM176 family RPN2_C PF18004.1 EGG23706.1 - 0.0021 18.0 7.4 0.0034 17.3 7.4 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain Zip PF02535.22 EGG23706.1 - 0.0024 17.2 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4637 PF15470.6 EGG23706.1 - 0.0028 17.4 6.8 0.0044 16.8 6.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) NOA36 PF06524.12 EGG23706.1 - 0.011 15.0 15.5 0.017 14.4 15.5 1.2 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 EGG23706.1 - 0.021 14.8 5.3 0.032 14.1 5.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.12 EGG23706.1 - 0.025 12.8 10.1 0.033 12.4 10.1 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 EGG23706.1 - 0.034 12.6 16.0 0.045 12.2 16.0 1.1 1 0 0 1 1 1 0 Mpp10 protein PPP4R2 PF09184.11 EGG23706.1 - 0.041 13.5 16.0 0.074 12.6 16.0 1.4 1 0 0 1 1 1 0 PPP4R2 SprA-related PF12118.8 EGG23706.1 - 0.043 12.9 5.5 0.062 12.4 5.5 1.1 1 0 0 1 1 1 0 SprA-related family FAM176 PF14851.6 EGG23706.1 - 0.045 13.4 7.3 0.086 12.5 7.3 1.5 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 EGG23706.1 - 0.047 13.5 9.9 0.073 12.9 9.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.12 EGG23706.1 - 0.063 12.7 13.2 0.093 12.1 13.2 1.2 1 0 0 1 1 1 0 SDA1 AAA_23 PF13476.6 EGG23706.1 - 0.07 13.6 13.8 0.07 13.6 12.3 1.6 2 0 0 2 2 1 0 AAA domain CPSF100_C PF13299.6 EGG23706.1 - 0.1 12.8 5.1 0.15 12.3 5.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SLM4 PF16818.5 EGG23706.1 - 0.15 12.0 4.9 0.27 11.2 4.9 1.4 1 0 0 1 1 1 0 Protein SLM4 Presenilin PF01080.17 EGG23706.1 - 0.22 10.2 6.3 0.29 9.8 6.3 1.2 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 EGG23706.1 - 0.24 10.2 6.9 0.32 9.7 6.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NAD_binding_4 PF07993.12 EGG23706.1 - 0.28 10.3 1.7 5.5 6.1 2.2 2.1 2 0 0 2 2 2 0 Male sterility protein RNA_pol_Rpc4 PF05132.14 EGG23706.1 - 0.36 11.3 3.8 0.56 10.6 3.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RXT2_N PF08595.11 EGG23706.1 - 0.37 10.8 13.0 0.6 10.1 13.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Med19 PF10278.9 EGG23706.1 - 0.42 10.5 10.4 0.61 10.0 10.4 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RAB3GAP2_C PF14656.6 EGG23706.1 - 0.74 8.0 3.6 0.9 7.7 3.6 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus CDC45 PF02724.14 EGG23706.1 - 0.76 8.0 10.2 1 7.6 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RPA43_OB PF17875.1 EGG23706.1 - 0.79 10.4 6.8 1.6 9.4 6.8 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Peptidase_S49_N PF08496.10 EGG23706.1 - 0.99 9.5 3.8 1.4 8.9 3.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DNA_pol_phi PF04931.13 EGG23706.1 - 1 7.4 16.6 1.5 6.8 16.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP_sp32 PF07222.12 EGG23706.1 - 1.2 8.6 8.5 1.9 7.9 8.5 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF4820 PF16091.5 EGG23706.1 - 1.4 8.2 7.2 2.3 7.5 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) V_ATPase_I PF01496.19 EGG23706.1 - 1.5 6.6 11.7 2.5 5.9 11.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PTPRCAP PF15713.5 EGG23706.1 - 1.5 9.1 14.2 2.4 8.4 14.2 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Connexin PF00029.19 EGG23706.1 - 1.6 8.4 7.6 2.7 7.7 7.6 1.3 1 0 0 1 1 1 0 Connexin ORC_WH_C PF18137.1 EGG23706.1 - 1.8 8.6 11.5 3.4 7.7 11.5 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal TFB6 PF17110.5 EGG23706.1 - 2.5 7.8 8.7 4.8 6.9 8.7 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF3464 PF11947.8 EGG23706.1 - 5 6.9 6.9 8.9 6.0 6.9 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CobT PF06213.12 EGG23706.1 - 5.7 6.2 14.1 8.5 5.7 14.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT EIIBC-GUT_N PF03612.14 EGG23706.1 - 6 6.6 7.0 10 5.8 7.0 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RP-C_C PF11800.8 EGG23706.1 - 6.2 6.9 6.6 9 6.3 6.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4337 PF14235.6 EGG23706.1 - 7.6 6.6 7.5 12 6.0 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Sporozoite_P67 PF05642.11 EGG23706.1 - 8.9 4.3 7.6 12 3.8 7.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRM_1 PF00076.22 EGG23707.1 - 0.032 14.0 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG23708.1 - 5e-35 119.8 0.0 1.3e-27 95.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EGG23708.1 - 3.3e-19 68.5 0.0 2.3e-07 30.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 EGG23708.1 - 2.3e-07 30.9 0.0 5e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 EGG23708.1 - 9.2e-06 25.4 0.0 0.0025 17.7 0.1 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EGG23708.1 - 0.0046 17.0 0.0 3.9 7.6 0.0 2.7 3 0 0 3 3 3 2 Limkain b1 SUIM_assoc PF16619.5 EGG23708.1 - 0.0082 16.2 0.2 0.016 15.3 0.2 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 RL PF17797.1 EGG23708.1 - 0.058 13.4 0.0 0.55 10.2 0.0 2.6 2 0 0 2 2 2 0 RL domain AAA_16 PF13191.6 EGG23709.1 - 0.00029 21.3 0.0 0.00049 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EGG23709.1 - 0.0066 16.8 0.0 0.019 15.3 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGG23709.1 - 0.038 14.3 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGG23709.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RCC1 PF00415.18 EGG23711.1 - 4.5e-33 113.6 15.8 2.5e-06 28.0 0.3 10.0 9 1 0 9 9 9 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG23711.1 - 4.5e-29 99.6 26.8 1.6e-11 43.7 0.4 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat hSac2 PF12456.8 EGG23711.1 - 3.3e-14 52.6 0.4 8.3e-14 51.3 0.1 1.8 2 0 0 2 2 2 1 Inositol phosphatase ASL_C PF08328.11 EGG23711.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal DEAD PF00270.29 EGG23712.1 - 1e-43 149.2 0.0 2e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG23712.1 - 4.4e-26 91.4 0.0 1.2e-25 90.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 EGG23712.1 - 1.1e-21 77.2 0.6 2.8e-21 75.8 0.6 1.8 1 0 0 1 1 1 1 SPRY domain AAA_22 PF13401.6 EGG23712.1 - 0.1 12.8 0.1 0.64 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ACOX PF01756.19 EGG23713.1 - 2.7e-26 92.2 0.0 4.9e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGG23713.1 - 2.2e-15 56.6 0.0 3.8e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGG23713.1 - 3.9e-11 43.4 0.4 6.3e-11 42.7 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EGG23714.1 - 1.4e-17 63.6 0.2 2.9e-17 62.6 0.2 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EGG23714.1 - 3.6e-14 53.2 16.2 3.6e-14 53.2 16.2 1.9 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Bax1-I PF01027.20 EGG23714.1 - 0.00051 19.9 9.8 0.00072 19.4 9.8 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF373 PF04123.13 EGG23714.1 - 0.52 9.7 2.2 0.77 9.1 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF1754 PF08555.10 EGG23715.1 - 0.013 16.3 7.4 0.013 16.3 7.4 2.1 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) RNA_pol_Rpc4 PF05132.14 EGG23715.1 - 0.018 15.5 0.4 0.48 10.9 0.2 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 Miga PF10265.9 EGG23715.1 - 0.2 10.6 5.6 0.32 9.9 5.6 1.3 1 0 0 1 1 1 0 Mitoguardin Pex14_N PF04695.13 EGG23715.1 - 0.4 11.3 7.0 1e+02 3.5 0.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BT1 PF03092.16 EGG23715.1 - 0.82 7.8 3.1 0.26 9.5 0.5 1.4 2 0 0 2 2 2 0 BT1 family PBP1_TM PF14812.6 EGG23715.1 - 0.94 9.9 14.1 0.59 10.5 0.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sec62 PF03839.16 EGG23715.1 - 0.97 8.9 9.4 39 3.7 0.0 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 Afi1 PF07792.12 EGG23715.1 - 1.6 9.2 18.6 0.89 10.0 9.9 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Folate_carrier PF01770.18 EGG23715.1 - 2.7 6.7 3.6 0.37 9.5 0.1 1.6 2 0 0 2 2 2 0 Reduced folate carrier EIIBC-GUT_N PF03612.14 EGG23715.1 - 3 7.6 6.3 4.6 6.9 4.5 2.2 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Rxt3 PF08642.10 EGG23715.1 - 3.1 8.6 8.3 0.15 12.9 1.3 2.1 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 CSRNP_N PF16019.5 EGG23715.1 - 4.3 7.2 10.5 0.58 10.0 5.2 1.9 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Ctr PF04145.15 EGG23715.1 - 8.2 7.0 9.0 0.29 11.8 0.7 2.3 2 1 0 2 2 2 0 Ctr copper transporter family Serinc PF03348.15 EGG23715.1 - 9.4 5.0 5.9 2.4 7.0 1.2 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) CPSF100_C PF13299.6 EGG23715.1 - 10 6.3 10.7 2.6 8.2 5.2 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Acetyltransf_4 PF13420.7 EGG23716.1 - 0.019 15.1 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-RING_5 PF14634.6 EGG23718.1 - 6.4e-05 22.8 1.0 6.4e-05 22.8 1.0 3.9 4 0 0 4 4 4 1 zinc-RING finger domain zf-UBR PF02207.20 EGG23718.1 - 8.2e-05 22.7 9.1 8.2e-05 22.7 9.1 3.3 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.6 EGG23718.1 - 0.0019 18.5 1.1 0.0019 18.5 1.1 4.0 4 0 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG23718.1 - 0.11 12.6 5.7 0.32 11.1 0.6 3.0 2 0 0 2 2 2 0 RING-type zinc-finger DUF4481 PF14800.6 EGG23718.1 - 1 8.8 6.3 3.5 7.0 6.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) Senescence_reg PF04520.13 EGG23718.1 - 1.2 10.0 12.3 0.072 13.9 7.1 1.5 2 0 0 2 2 2 0 Senescence regulator DUF4175 PF13779.6 EGG23718.1 - 4.9 4.9 14.1 7.2 4.4 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spt20 PF12090.8 EGG23718.1 - 8.1 6.0 22.8 0.25 10.9 9.0 2.5 2 0 0 2 2 2 0 Spt20 family Pkinase PF00069.25 EGG23719.1 - 8.1e-75 251.6 0.0 1e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23719.1 - 1.6e-36 125.9 0.0 2.2e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EGG23719.1 - 1.5e-07 31.9 5.8 8.5e-07 29.5 2.0 2.8 2 1 1 3 3 3 1 PH domain Pkinase_C PF00433.24 EGG23719.1 - 0.00014 22.5 0.1 0.00027 21.6 0.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGG23719.1 - 0.0015 17.9 0.0 0.19 11.0 0.0 2.4 1 1 1 2 2 2 2 Kinase-like PH_11 PF15413.6 EGG23719.1 - 0.0016 18.9 0.2 0.0047 17.3 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain FTA2 PF13095.6 EGG23719.1 - 0.0047 16.6 0.0 1.3 8.6 0.1 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGG23719.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RabGAP-TBC PF00566.18 EGG23720.1 - 6e-52 176.4 0.0 6e-52 176.4 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Macoilin PF09726.9 EGG23720.1 - 0.042 12.4 6.3 0.087 11.4 6.3 1.5 1 0 0 1 1 1 0 Macoilin family Orbi_VP3 PF01700.16 EGG23720.1 - 0.12 10.2 0.2 0.18 9.7 0.2 1.1 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein DUF2165 PF09933.9 EGG23721.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) DUF2967 PF11179.8 EGG23721.1 - 2.5 6.1 5.0 3.8 5.5 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF2613 PF11021.8 EGG23722.1 - 0.056 13.6 0.2 0.15 12.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) EGF_2 PF07974.13 EGG23722.1 - 1.1 9.7 13.8 2.2 8.7 13.8 1.5 1 0 0 1 1 1 0 EGF-like domain ChW PF07538.11 EGG23723.1 - 9.1e-26 89.5 3.2 1.6e-12 47.1 0.1 3.3 3 0 0 3 3 3 3 Clostridial hydrophobic W Amastin PF07344.11 EGG23724.1 - 0.00026 20.9 3.1 0.00054 19.8 2.9 1.8 1 1 0 1 1 1 1 Amastin surface glycoprotein L_HMGIC_fpl PF10242.9 EGG23724.1 - 0.0044 17.3 2.8 0.0044 17.3 2.8 1.7 1 1 1 2 2 2 1 Lipoma HMGIC fusion partner-like protein DUF202 PF02656.15 EGG23724.1 - 0.013 15.9 1.9 0.013 15.9 1.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF4579 PF15158.6 EGG23724.1 - 0.024 14.4 0.2 4.1 7.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) Sigma_reg_N PF13800.6 EGG23724.1 - 0.029 14.6 5.0 7.1 7.0 1.5 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Glyco_hydro_63 PF03200.16 EGG23724.1 - 0.1 11.4 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain Viral_Beta_CD PF04530.12 EGG23724.1 - 0.23 11.8 0.1 0.23 11.8 0.1 2.5 1 1 1 2 2 2 0 Viral Beta C/D like family Claudin_2 PF13903.6 EGG23724.1 - 0.25 11.1 13.5 3 7.6 13.5 2.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 EGG23724.1 - 0.62 9.9 9.1 0.76 9.6 6.6 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.12 EGG23724.1 - 3.3 7.3 20.3 0.027 14.1 6.5 2.7 1 1 2 3 3 3 0 SUR7/PalI family Clavanin PF05452.11 EGG23724.1 - 9.5 6.5 6.4 0.74 10.1 0.2 2.2 2 1 0 2 2 2 0 Clavanin BTB_2 PF02214.22 EGG23725.1 - 2.1e-13 50.4 0.0 1.8e-08 34.6 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain DUSP PF06337.12 EGG23725.1 - 2.5e-11 44.0 3.8 5.4e-11 43.0 0.4 2.8 3 1 0 3 3 3 1 DUSP domain Claudin_2 PF13903.6 EGG23725.1 - 0.0075 16.0 0.2 0.0075 16.0 0.2 1.7 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction LMBR1 PF04791.16 EGG23725.1 - 0.017 14.1 1.7 0.02 13.8 0.3 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein DCP1 PF06058.13 EGG23725.1 - 0.027 14.4 0.5 0.16 11.9 0.1 2.4 3 0 0 3 3 3 0 Dcp1-like decapping family SUR7 PF06687.12 EGG23725.1 - 1.7 8.2 8.5 1.3 8.6 6.3 1.8 1 1 1 2 2 2 0 SUR7/PalI family MMPL PF03176.15 EGG23725.1 - 4.6 6.1 8.6 1.4 7.7 5.4 1.7 2 0 0 2 2 2 0 MMPL family SnoaL_2 PF12680.7 EGG23726.1 - 6.1e-08 33.2 0.0 0.00079 20.0 0.0 2.4 2 0 0 2 2 2 2 SnoaL-like domain DUF4440 PF14534.6 EGG23726.1 - 2.4e-05 24.7 0.0 0.2 12.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4440) SnoaL PF07366.12 EGG23726.1 - 0.00075 19.3 0.3 0.3 10.9 0.3 3.1 2 1 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 EGG23726.1 - 0.014 15.6 0.0 7.1 6.9 0.0 2.5 2 0 0 2 2 2 0 SnoaL-like domain Lumazine_bd_2 PF12893.7 EGG23726.1 - 0.022 15.5 0.0 7.3 7.3 0.0 2.7 2 0 0 2 2 2 0 Putative lumazine-binding Spt20 PF12090.8 EGG23726.1 - 0.11 12.0 18.6 0.24 11.0 18.6 1.6 1 0 0 1 1 1 0 Spt20 family APOBEC1 PF18769.1 EGG23726.1 - 0.29 11.4 5.6 0.25 11.6 0.6 3.0 3 0 0 3 3 3 0 APOBEC1 Ank_4 PF13637.6 EGG23727.1 - 2.4e-20 72.6 1.6 1.2e-07 32.1 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) RGS PF00615.19 EGG23727.1 - 1e-18 67.7 0.7 2.6e-17 63.2 0.7 2.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain Ank_5 PF13857.6 EGG23727.1 - 1.1e-18 67.0 3.5 7.3e-07 29.3 0.1 5.2 3 2 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG23727.1 - 1.3e-18 67.4 1.8 1.6e-07 31.8 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG23727.1 - 3.1e-14 51.7 0.3 0.0047 17.3 0.0 6.3 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EGG23727.1 - 1.4e-12 47.5 0.7 0.051 14.0 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat DUF3447 PF11929.8 EGG23728.1 - 0.00075 19.4 2.7 0.25 11.3 0.1 4.0 3 1 1 4 4 4 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 EGG23728.1 - 0.0032 18.0 1.3 34 5.1 0.0 5.3 5 1 1 6 6 6 1 Ankyrin repeats (3 copies) DUF2856 PF11043.8 EGG23728.1 - 0.053 13.6 0.2 0.89 9.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) SUI1 PF01253.22 EGG23729.1 - 3.5e-22 78.7 2.5 7e-22 77.8 0.1 2.7 2 0 0 2 2 2 1 Translation initiation factor SUI1 zf-C3HC4_3 PF13920.6 EGG23729.1 - 9e-09 35.1 8.2 1.5e-08 34.3 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG23729.1 - 3.6e-08 33.1 9.1 6.7e-08 32.3 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG23729.1 - 2.2e-06 27.4 7.4 4e-06 26.6 7.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGG23729.1 - 4.2e-06 26.5 11.8 8.8e-06 25.5 11.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG23729.1 - 2.2e-05 24.4 4.7 2.5e-05 24.2 2.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG23729.1 - 3.4e-05 23.7 10.1 7.7e-05 22.6 10.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGG23729.1 - 0.00016 22.0 9.4 0.00028 21.1 9.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGG23729.1 - 0.0014 18.9 5.7 0.0036 17.6 5.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EGG23729.1 - 0.0049 16.7 3.0 0.0049 16.7 3.0 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EGG23729.1 - 0.019 15.0 2.8 0.039 14.0 2.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGG23729.1 - 0.39 10.9 8.8 0.91 9.7 8.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EGG23729.1 - 0.74 9.7 6.0 1.8 8.5 6.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 EGG23729.1 - 5.7 6.8 8.2 58 3.6 0.0 2.7 2 0 0 2 2 2 0 RING-like zinc finger Ank_2 PF12796.7 EGG23730.1 - 6.6e-07 29.8 1.6 1.1 9.9 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG23730.1 - 0.0076 16.8 1.3 15 6.3 0.0 4.3 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23730.1 - 0.4 11.4 5.3 15 6.5 0.0 4.6 5 0 0 5 5 5 0 Ankyrin repeat TFIIA PF03153.13 EGG23730.1 - 9.3 6.1 33.8 0.064 13.2 7.5 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit RhoGAP PF00620.27 EGG23731.1 - 3.5e-32 111.3 1.0 7.5e-32 110.3 1.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Annexin PF00191.20 EGG23733.1 - 5.6e-80 263.4 6.2 4.8e-24 84.2 0.1 4.1 4 0 0 4 4 4 4 Annexin Phosphonate-bd PF12974.7 EGG23734.1 - 2e-08 34.2 0.0 3.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Ank_2 PF12796.7 EGG23735.1 - 1.4e-25 89.7 10.2 9.9e-11 42.1 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) BK_channel_a PF03493.18 EGG23735.1 - 3.4e-25 88.1 0.6 1e-21 76.9 0.1 2.9 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Ank_4 PF13637.6 EGG23735.1 - 4.9e-24 84.4 4.3 1.7e-10 41.2 0.1 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EGG23735.1 - 2.7e-22 78.2 11.9 4.3e-05 23.7 0.3 7.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EGG23735.1 - 2.4e-20 70.4 4.0 0.0025 18.2 0.0 7.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EGG23735.1 - 3e-20 72.0 7.6 3.7e-07 30.3 0.1 5.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) TIG PF01833.24 EGG23735.1 - 1.1e-13 51.0 0.5 1.1e-13 51.0 0.5 2.3 2 0 0 2 2 2 1 IPT/TIG domain Ion_trans_2 PF07885.16 EGG23735.1 - 2.3e-13 49.9 6.2 7.3e-13 48.3 6.2 1.8 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 EGG23735.1 - 6.5e-05 23.2 0.0 0.0065 16.7 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain CRA PF06589.11 EGG23735.1 - 0.00038 20.5 1.8 0.00038 20.5 1.8 4.6 4 1 1 5 5 3 1 Circumsporozoite-related antigen (CRA) Castor_Poll_mid PF06241.12 EGG23735.1 - 0.00062 19.7 0.5 0.005 16.8 0.0 2.8 2 1 0 2 2 2 1 Castor and Pollux, part of voltage-gated ion channel Lig_chan PF00060.26 EGG23735.1 - 0.032 14.1 0.5 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Ligand-gated ion channel OGG_N PF07934.12 EGG23736.1 - 9.9e-20 70.8 0.7 9.9e-20 70.8 0.7 2.1 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EGG23736.1 - 1e-15 58.1 0.0 2.2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGG23736.1 - 0.0025 17.6 0.0 0.01 15.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif RXT2_N PF08595.11 EGG23736.1 - 0.012 15.6 14.7 0.13 12.3 6.1 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 EGG23736.1 - 0.27 11.6 0.1 0.27 11.6 0.1 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain RNA_pol_Rpc4 PF05132.14 EGG23736.1 - 1.8 9.0 8.1 3.9 7.9 2.8 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 NOA36 PF06524.12 EGG23736.1 - 2.3 7.5 15.5 1.8 7.9 4.8 2.4 2 0 0 2 2 2 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EGG23736.1 - 8.1 6.6 19.6 3.2 8.0 6.3 2.9 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3504 PF12012.8 EGG23736.1 - 8.5 6.3 10.5 3.9 7.4 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3504) Fer4_19 PF06902.11 EGG23737.1 - 0.045 13.8 0.5 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Phage_Gp23 PF10669.9 EGG23738.1 - 0.0052 17.1 0.5 0.0057 17.0 0.5 1.0 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) CIAPIN1 PF05093.13 EGG23739.1 - 1.9e-20 73.3 14.7 3.8e-19 69.1 14.7 2.3 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis ABC_tran PF00005.27 EGG23740.1 - 6.8e-26 91.4 0.0 1.4e-25 90.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGG23740.1 - 9.9e-23 80.8 32.4 1.4e-22 80.3 32.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGG23740.1 - 8.7e-10 38.9 0.3 1.8e-05 24.7 0.0 2.9 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGG23740.1 - 0.00069 20.2 0.8 0.0027 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EGG23740.1 - 0.00084 18.8 0.1 0.012 15.1 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGG23740.1 - 0.001 19.3 0.0 0.014 15.6 0.0 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGG23740.1 - 0.14 12.0 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4162 PF13732.6 EGG23740.1 - 0.14 12.9 0.4 0.76 10.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) PolyA_pol PF01743.20 EGG23741.1 - 4.9e-29 101.3 0.1 4.9e-29 101.3 0.1 2.2 2 1 1 3 3 3 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EGG23741.1 - 1.3e-05 24.9 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 EGG23741.1 - 0.064 13.2 0.1 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Ribo_biogen_C PF04034.13 EGG23742.1 - 8.8e-53 177.4 0.0 1.5e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EGG23742.1 - 1.8e-13 50.1 0.0 4.7e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Nop14 PF04147.12 EGG23742.1 - 0.0021 16.4 43.1 0.0027 16.0 43.1 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 EGG23742.1 - 0.0024 16.3 36.0 0.003 16.0 36.0 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 EGG23742.1 - 0.0029 17.1 41.5 0.004 16.6 41.5 1.2 1 0 0 1 1 1 1 SDA1 Merozoite_SPAM PF07133.11 EGG23742.1 - 0.013 15.6 52.1 0.022 14.8 52.1 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) BUD22 PF09073.10 EGG23742.1 - 0.09 12.1 36.7 0.12 11.7 36.7 1.2 1 0 0 1 1 1 0 BUD22 Nop53 PF07767.11 EGG23742.1 - 0.84 9.0 39.9 1.4 8.2 39.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Hid1 PF12722.7 EGG23742.1 - 1.3 7.0 22.3 1.6 6.7 22.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Drc1-Sld2 PF11719.8 EGG23742.1 - 2.5 7.6 27.3 3.2 7.2 27.3 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein GAGA_bind PF06217.12 EGG23742.1 - 3.7 7.8 11.1 4.9 7.4 11.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family LTV PF04180.14 EGG23742.1 - 3.8 7.1 34.0 5.7 6.6 34.0 1.2 1 0 0 1 1 1 0 Low temperature viability protein RR_TM4-6 PF06459.12 EGG23742.1 - 5 6.9 29.5 7.1 6.4 29.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 tRNA-synt_2 PF00152.20 EGG23743.1 - 3.1e-71 240.0 0.2 5.4e-71 239.2 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGG23743.1 - 5e-07 29.6 0.1 9.5e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGG23743.1 - 0.0048 16.4 0.3 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF3535 PF12054.8 EGG23743.1 - 0.01 15.1 0.5 0.01 15.1 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3535) Mago_nashi PF02792.14 EGG23744.1 - 1.7e-69 232.4 0.6 2e-69 232.2 0.6 1.1 1 0 0 1 1 1 1 Mago nashi protein DHO_dh PF01180.21 EGG23745.1 - 1.2e-22 80.5 0.1 1.2e-20 73.9 0.1 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase Dus PF01207.17 EGG23745.1 - 9.5e-05 21.6 0.5 0.0011 18.2 0.2 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Aldolase PF01081.19 EGG23745.1 - 0.0077 15.7 0.0 2.6 7.4 0.0 2.5 3 0 0 3 3 3 2 KDPG and KHG aldolase YqgF PF14639.6 EGG23745.1 - 0.17 11.7 0.4 1.3 8.8 0.1 2.2 1 1 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 MACPF PF01823.19 EGG23746.1 - 1.4e-21 77.6 0.6 1.4e-21 77.6 0.6 1.7 2 0 0 2 2 2 1 MAC/Perforin domain CBM49 PF09478.10 EGG23746.1 - 0.018 15.4 0.6 0.053 13.8 0.6 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 MACPF PF01823.19 EGG23747.1 - 4.6e-21 75.9 2.2 8.4e-21 75.0 2.2 1.4 1 0 0 1 1 1 1 MAC/Perforin domain MACPF PF01823.19 EGG23748.1 - 1.5e-21 77.5 2.1 3.4e-21 76.3 1.3 2.0 2 0 0 2 2 2 1 MAC/Perforin domain AAT PF03417.16 EGG23749.1 - 0.0027 17.4 0.0 0.0084 15.8 0.0 1.8 3 0 0 3 3 3 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Bac_GH3_C PF18034.1 EGG23749.1 - 0.02 14.6 0.1 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain Arf PF00025.21 EGG23749.1 - 0.031 13.7 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Ank_2 PF12796.7 EGG23750.1 - 1.5e-46 156.9 3.9 3.2e-14 53.3 0.1 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG23750.1 - 8.6e-36 117.9 0.5 0.00016 21.8 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 EGG23750.1 - 1.9e-31 108.0 0.9 4.5e-07 30.3 0.0 8.0 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 EGG23750.1 - 1.2e-25 88.8 11.3 0.00033 21.0 0.2 10.7 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 EGG23750.1 - 6.9e-25 86.8 5.4 9.8e-06 25.8 0.0 8.4 2 2 7 9 9 9 9 Ankyrin repeats (many copies) MIR PF02815.19 EGG23750.1 - 1.3e-15 57.7 1.2 5.3e-09 36.2 0.0 3.2 1 1 2 3 3 3 3 MIR domain Ins145_P3_rec PF08709.11 EGG23750.1 - 5.1e-06 25.8 0.6 3e-05 23.3 0.4 2.2 1 1 1 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Frataxin_Cyay PF01491.16 EGG23751.1 - 4.8e-05 23.4 3.9 0.00022 21.3 0.1 2.2 2 1 0 2 2 2 1 Frataxin-like domain Microvir_H PF04687.12 EGG23751.1 - 0.082 12.3 2.0 0.1 11.9 2.0 1.0 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) PolC_DP2 PF03833.13 EGG23751.1 - 0.11 10.3 0.1 0.14 10.0 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 RhoGEF PF00621.20 EGG23752.1 - 9.6e-48 162.8 0.8 9.6e-48 162.8 0.8 2.7 3 0 0 3 3 3 1 RhoGEF domain Arm PF00514.23 EGG23752.1 - 2.6e-25 87.6 9.5 3.1e-07 30.2 0.1 8.9 10 0 0 10 10 10 5 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 EGG23752.1 - 3.5e-09 36.5 22.5 0.0018 17.8 8.6 5.5 3 1 0 4 4 4 3 Armadillo-like HEAT PF02985.22 EGG23752.1 - 0.0015 18.6 2.2 0.78 10.2 0.3 4.7 4 0 0 4 4 4 1 HEAT repeat PH PF00169.29 EGG23752.1 - 0.002 18.6 0.1 0.0061 17.1 0.1 1.9 1 0 0 1 1 1 1 PH domain HEAT_EZ PF13513.6 EGG23752.1 - 0.043 14.3 5.3 5.3 7.7 0.1 4.2 5 0 0 5 5 5 0 HEAT-like repeat RIH_assoc PF08454.11 EGG23752.1 - 5.3 7.0 6.9 5.2 7.0 1.8 3.4 3 0 0 3 3 3 0 RyR and IP3R Homology associated Diphthamide_syn PF01866.17 EGG23753.1 - 1.9e-82 277.1 7.3 2.2e-80 270.3 7.3 2.2 1 1 0 1 1 1 1 Putative diphthamide synthesis protein DUF2064 PF09837.9 EGG23753.1 - 0.019 14.8 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) MPP6 PF10175.9 EGG23753.1 - 0.43 11.1 6.5 7.4 7.1 0.5 2.4 2 0 0 2 2 2 0 M-phase phosphoprotein 6 DoxA PF07680.11 EGG23754.1 - 0.14 12.1 3.2 0.09 12.7 0.7 2.0 2 0 0 2 2 2 0 TQO small subunit DoxA EGF_2 PF07974.13 EGG23754.1 - 0.22 11.9 6.1 0.57 10.6 6.1 1.7 1 0 0 1 1 1 0 EGF-like domain LRR_4 PF12799.7 EGG23754.1 - 0.4 11.2 22.5 0.46 11.0 1.9 6.8 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) EMP70 PF02990.16 EGG23756.1 - 1.1e-116 390.6 26.0 1.1e-116 390.6 26.0 1.5 2 0 0 2 2 2 1 Endomembrane protein 70 DUF3309 PF11752.8 EGG23756.1 - 0.02 15.0 3.0 0.02 15.0 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) Coiled PF05710.12 EGG23757.1 - 0.00011 22.9 1.9 0.00012 22.8 1.9 1.1 1 0 0 1 1 1 1 Coiled coil Rad60-SLD PF11976.8 EGG23759.1 - 1.1e-07 31.6 0.0 2.7e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGG23759.1 - 1.1e-05 25.0 0.0 3.1e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family TFIIA PF03153.13 EGG23759.1 - 0.24 11.4 35.6 0.31 11.0 35.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2407 PF10302.9 EGG23759.1 - 0.68 10.5 0.0 0.68 10.5 0.0 3.0 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain GREB1 PF15782.5 EGG23759.1 - 2.4 5.2 17.5 2.9 4.9 17.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Menin PF05053.13 EGG23759.1 - 3.9 5.7 12.0 4.9 5.4 12.0 1.2 1 0 0 1 1 1 0 Menin DUF1387 PF07139.11 EGG23759.1 - 6.2 6.5 15.2 8.1 6.1 15.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Rib PF08428.10 EGG23760.1 - 0.11 12.5 0.5 0.58 10.2 0.2 2.0 1 1 1 2 2 2 0 Rib/alpha-like repeat GRDP-like PF07173.12 EGG23760.1 - 2.1 9.0 6.9 3.8 8.2 0.4 2.5 1 1 1 2 2 2 0 Glycine-rich domain-containing protein-like DnaJ-X PF14308.6 EGG23761.1 - 4.5e-27 94.9 3.3 4.5e-27 94.9 3.3 2.5 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGG23761.1 - 1.6e-26 92.2 6.6 4.6e-26 90.7 6.6 1.9 1 0 0 1 1 1 1 DnaJ domain Armet PF10208.9 EGG23761.1 - 0.00014 21.8 0.2 0.00049 20.1 0.0 2.0 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding Mucin PF01456.17 EGG23761.1 - 0.004 17.2 13.7 0.0061 16.6 13.7 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein bZIP_C PF12498.8 EGG23763.1 - 2.4 9.1 6.5 1.5 9.8 0.1 3.2 3 0 0 3 3 3 0 Basic leucine-zipper C terminal Mito_carr PF00153.27 EGG23765.1 - 6e-64 212.0 0.8 1e-23 83.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGG23765.1 - 0.066 12.4 0.2 1.6 7.8 0.0 2.3 1 1 2 3 3 3 0 Gammaproteobacterial serine protease PTR2 PF00854.21 EGG23766.1 - 5.2e-63 213.2 18.9 5.2e-63 213.2 18.9 1.7 2 0 0 2 2 2 1 POT family MFS_1 PF07690.16 EGG23766.1 - 2.8e-11 43.0 29.7 1.8e-09 37.0 28.7 3.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 EGG23766.1 - 0.31 11.1 4.5 2.3 8.3 0.0 3.3 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Halogen_Hydrol PF10112.9 EGG23766.1 - 0.98 9.4 0.0 0.98 9.4 0.0 2.6 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein MerC PF03203.14 EGG23766.1 - 1.4 9.4 18.5 2 8.9 5.3 3.3 3 0 0 3 3 3 0 MerC mercury resistance protein DUF2070 PF09843.9 EGG23766.1 - 1.9 6.7 25.4 1.8 6.8 8.6 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF3671 PF12420.8 EGG23766.1 - 4 7.5 23.4 0.12 12.5 1.8 4.8 3 2 2 5 5 5 0 Protein of unknown function DUF3328 PF11807.8 EGG23766.1 - 4.1 7.1 4.6 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) PTR2 PF00854.21 EGG23767.1 - 4.8e-65 219.9 6.3 4.8e-65 219.9 6.3 1.6 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 EGG23767.1 - 9.5e-15 54.4 22.4 1.5e-14 53.7 12.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGG23767.1 - 0.00014 20.3 2.3 0.0063 14.9 0.5 3.6 3 2 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family PTR2 PF00854.21 EGG23769.1 - 2.1e-77 260.6 7.3 3.2e-77 260.0 7.3 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EGG23769.1 - 7.5e-14 51.4 9.9 1.8e-09 37.0 5.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 EGG23769.1 - 6.1 6.5 13.6 22 4.7 0.3 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) PTR2 PF00854.21 EGG23771.1 - 2e-89 300.2 6.4 3.4e-89 299.4 6.4 1.2 1 0 0 1 1 1 1 POT family Ank_2 PF12796.7 EGG23771.1 - 6.1e-23 81.2 4.0 2e-05 25.1 0.0 7.0 5 1 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG23771.1 - 1.5e-13 50.9 6.5 0.015 15.9 0.0 8.5 6 2 3 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23771.1 - 4.8e-12 44.9 12.4 5 8.0 0.0 11.8 13 0 0 13 13 13 3 Ankyrin repeat MFS_1 PF07690.16 EGG23771.1 - 6.8e-05 22.0 27.7 0.0002 20.4 23.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_5 PF13857.6 EGG23771.1 - 0.00015 22.0 1.0 66 4.0 0.0 7.0 5 2 1 6 6 6 0 Ankyrin repeats (many copies) Ank PF00023.30 EGG23771.1 - 0.025 15.0 7.5 33 5.1 0.2 7.5 7 1 0 7 7 7 0 Ankyrin repeat Vut_1 PF02592.15 EGG23771.1 - 3.8 7.8 9.5 7 7.0 8.1 2.3 2 0 0 2 2 2 0 Putative vitamin uptake transporter Phospholip_B PF04916.13 EGG23772.1 - 7.7e-177 589.1 19.1 9.4e-177 588.8 19.1 1.0 1 0 0 1 1 1 1 Phospholipase B RasGEF PF00617.19 EGG23773.1 - 1.6e-48 165.2 0.7 4.9e-48 163.7 0.1 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGG23773.1 - 4.2e-12 46.2 1.3 4.2e-12 46.2 1.3 2.7 2 2 0 2 2 2 1 RasGEF N-terminal motif LisH_TPL PF17814.1 EGG23773.1 - 0.00024 20.7 0.9 0.00024 20.7 0.9 2.4 3 0 0 3 3 3 1 LisH-like dimerisation domain Thioredoxin_6 PF13848.6 EGG23773.1 - 0.00074 19.5 1.0 0.0032 17.4 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain DUF713 PF05218.14 EGG23773.1 - 0.01 15.6 2.0 0.018 14.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF713) IFN-gamma PF00714.17 EGG23773.1 - 1.4 8.8 8.0 7.7 6.4 0.2 3.7 3 0 0 3 3 3 0 Interferon gamma zf-C3HC4 PF00097.25 EGG23774.1 - 7.8e-11 41.7 10.0 1.4e-10 40.8 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG23774.1 - 8e-11 41.6 10.3 1.2e-10 41.0 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG23774.1 - 1.6e-10 40.7 6.3 2.5e-10 40.1 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG23774.1 - 2.8e-09 37.2 11.4 4.3e-09 36.6 11.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG23774.1 - 4.4e-09 36.2 5.4 4.4e-09 36.2 5.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG23774.1 - 4.7e-09 36.1 9.5 7.6e-09 35.4 9.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGG23774.1 - 7.2e-08 32.5 10.3 1.1e-07 31.8 10.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGG23774.1 - 1.7e-06 27.8 8.8 3e-06 27.0 8.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGG23774.1 - 1.5e-05 25.2 7.2 3.9e-05 23.9 7.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 EGG23774.1 - 0.00012 21.8 3.5 0.00024 20.9 3.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Baculo_IE-1 PF05290.11 EGG23774.1 - 0.00045 20.2 3.1 0.00066 19.6 3.1 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 EGG23774.1 - 0.00049 19.9 2.8 0.00083 19.2 2.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EGG23774.1 - 0.00052 20.0 4.2 0.00095 19.2 4.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 EGG23774.1 - 0.002 17.5 1.6 0.002 17.5 1.6 2.2 1 1 1 2 2 2 1 Rtf2 RING-finger U-box PF04564.15 EGG23774.1 - 0.014 15.6 0.0 0.014 15.6 0.0 2.6 2 1 1 3 3 3 0 U-box domain zf-UDP PF14569.6 EGG23774.1 - 0.03 14.4 2.8 0.11 12.6 2.8 2.0 1 1 0 1 1 1 0 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 EGG23774.1 - 0.075 12.7 7.9 0.14 11.8 7.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 EGG23774.1 - 0.087 12.5 5.6 0.15 11.8 5.6 1.3 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 EGG23774.1 - 0.11 12.4 7.4 0.27 11.1 7.4 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Macoilin PF09726.9 EGG23774.1 - 0.28 9.7 13.3 0.31 9.5 13.3 1.1 1 0 0 1 1 1 0 Macoilin family zf-RING_10 PF16685.5 EGG23774.1 - 0.54 10.4 4.5 0.91 9.7 4.5 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Mucin PF01456.17 EGG23774.1 - 0.78 9.7 26.7 1.4 8.9 26.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Apt1 PF10351.9 EGG23774.1 - 0.9 8.3 11.2 1.2 7.9 11.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Opi1 PF08618.10 EGG23774.1 - 1.1 8.5 16.7 1.5 8.0 16.7 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 Endomucin PF07010.12 EGG23774.1 - 1.2 9.0 20.7 1.9 8.4 20.7 1.2 1 0 0 1 1 1 0 Endomucin zf-RING_11 PF17123.5 EGG23774.1 - 1.3 8.8 10.8 0.28 10.9 6.4 2.0 2 0 0 2 2 2 0 RING-like zinc finger LAP1C PF05609.12 EGG23774.1 - 2.5 7.1 11.1 2.9 6.9 11.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SPX PF03105.19 EGG23774.1 - 4.9 7.0 18.2 6.8 6.5 18.0 1.5 1 1 0 1 1 1 0 SPX domain UPF0560 PF10577.9 EGG23774.1 - 7.8 4.9 11.9 10 4.5 11.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 tRNA_int_end_N2 PF12928.7 EGG23775.1 - 7.2e-11 42.1 0.0 1.6e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EGG23775.1 - 0.015 14.9 0.2 0.036 13.7 0.2 1.6 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Mucin PF01456.17 EGG23775.1 - 1.2 9.1 17.0 1.5 8.8 12.1 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF2846 PF11008.8 EGG23776.1 - 0.19 11.8 2.4 0.37 10.8 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2846) PTH2 PF01981.16 EGG23777.1 - 8.5e-48 161.5 0.1 1.4e-47 160.8 0.1 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TMEM154 PF15102.6 EGG23777.1 - 0.45 10.4 6.6 0.47 10.4 5.6 1.4 1 1 0 1 1 1 0 TMEM154 protein family Asp PF00026.23 EGG23778.1 - 2.7e-44 151.9 2.7 1.2e-43 149.7 2.7 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGG23778.1 - 3.1e-18 66.6 4.0 6.3e-18 65.6 4.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGG23778.1 - 2.7e-15 56.5 0.1 3.9e-15 56.0 0.1 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF228 PF02989.14 EGG23778.1 - 0.093 12.5 0.1 0.27 11.0 0.1 1.7 1 1 1 2 2 2 0 Lyme disease proteins of unknown function Pkinase PF00069.25 EGG23779.1 - 1.7e-14 53.8 0.2 4e-14 52.6 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23779.1 - 1.4e-10 40.9 0.0 4.8e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase SRI PF08236.11 EGG23779.1 - 0.07 13.3 1.0 2.4 8.4 0.1 2.6 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain 7tm_3 PF00003.22 EGG23780.1 - 3.6e-29 102.2 32.6 9.1e-29 100.8 32.6 1.7 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Clat_adaptor_s PF01217.20 EGG23781.1 - 1.2e-50 171.1 4.4 1.4e-50 170.9 4.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain VPS13 PF16908.5 EGG23782.1 - 2.3e-63 214.2 20.8 2.7e-62 210.6 1.2 4.3 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EGG23782.1 - 1.6e-56 190.9 17.8 2.2e-55 187.2 0.5 4.0 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 EGG23782.1 - 2.9e-55 187.3 29.9 5.7e-51 173.2 8.2 6.5 5 2 1 6 6 6 3 Repeating coiled region of VPS13 SHR-BD PF06650.12 EGG23782.1 - 2e-30 106.1 5.3 2e-30 106.1 5.3 5.6 4 1 0 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 EGG23782.1 - 2.9e-23 82.2 1.1 2.9e-23 82.2 1.1 4.4 5 0 0 5 5 5 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EGG23782.1 - 9.7e-10 38.7 0.0 6e-09 36.1 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain V-SNARE_C PF12352.8 EGG23785.1 - 3e-07 30.6 3.0 3e-07 30.6 3.0 2.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Lebercilin PF15619.6 EGG23785.1 - 0.0027 17.4 1.6 0.0027 17.4 1.6 2.1 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Sin3_corepress PF08295.12 EGG23785.1 - 0.0076 16.3 0.2 0.0076 16.3 0.2 2.5 3 0 0 3 3 3 1 Sin3 family co-repressor Tropomyosin_1 PF12718.7 EGG23785.1 - 0.014 15.5 5.6 0.026 14.7 3.2 2.0 2 0 0 2 2 2 0 Tropomyosin like Sec20 PF03908.13 EGG23785.1 - 0.023 14.6 4.8 0.38 10.7 0.1 2.9 2 1 1 3 3 3 0 Sec20 Arfaptin PF06456.13 EGG23785.1 - 0.025 14.1 0.7 0.098 12.2 0.2 1.9 2 0 0 2 2 2 0 Arfaptin-like domain Laminin_II PF06009.12 EGG23785.1 - 0.032 14.2 4.4 0.49 10.4 0.9 2.3 2 0 0 2 2 2 0 Laminin Domain II Dor1 PF04124.12 EGG23785.1 - 0.048 12.3 2.8 0.073 11.7 2.8 1.2 1 0 0 1 1 1 0 Dor1-like family DUF948 PF06103.11 EGG23785.1 - 0.083 13.2 1.2 0.78 10.0 0.0 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tht1 PF04163.12 EGG23785.1 - 0.11 11.3 6.5 0.2 10.4 6.5 1.3 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein DUF848 PF05852.11 EGG23785.1 - 0.99 9.5 4.4 12 6.0 1.5 2.6 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Fib_alpha PF08702.10 EGG23785.1 - 1.7 8.8 7.3 8.9 6.5 0.2 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family adh_short PF00106.25 EGG23786.1 - 2.3e-39 134.9 0.0 3.2e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG23786.1 - 9.9e-31 107.1 0.0 1.2e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG23786.1 - 4.6e-11 43.0 0.0 7.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG23786.1 - 2.8e-06 27.0 0.1 1.7e-05 24.4 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGG23786.1 - 0.0034 16.5 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EGG23786.1 - 0.0063 16.1 0.0 0.031 13.9 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EGG23786.1 - 0.013 15.0 0.4 0.13 11.7 0.0 2.4 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EGG23787.1 - 8.5e-32 110.2 0.2 2e-21 76.3 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGG23787.1 - 1e-21 77.6 0.0 2.8e-15 56.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG23787.1 - 1.5e-08 34.7 0.0 7.3e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG23787.1 - 1.1e-05 25.0 0.0 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EGG23787.1 - 0.0015 18.2 0.0 0.061 12.9 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 EGG23787.1 - 0.0048 16.0 0.0 0.0068 15.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGG23787.1 - 0.014 14.8 0.1 0.15 11.4 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Kinesin PF00225.23 EGG23788.1 - 2.2e-106 355.6 4.3 2.2e-106 355.6 4.3 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGG23788.1 - 1.4e-58 197.0 0.6 1.4e-58 197.0 0.6 2.0 2 0 0 2 2 2 1 Microtubule binding AAT PF03417.16 EGG23789.1 - 0.0089 15.7 0.0 0.049 13.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Urocanase PF01175.18 EGG23789.1 - 0.025 14.2 0.2 0.043 13.4 0.2 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain Multi-haem_cyto PF13447.6 EGG23789.1 - 0.078 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH CybS PF05328.12 EGG23790.1 - 8e-11 41.8 0.2 9.8e-11 41.5 0.2 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit LMWPc PF01451.21 EGG23791.1 - 2.7e-35 121.8 0.1 2.9e-34 118.5 0.1 1.9 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Hemocyanin_M PF00372.19 EGG23792.1 - 3.1e-35 121.7 0.0 6.3e-35 120.7 0.0 1.5 2 0 0 2 2 2 1 Hemocyanin, copper containing domain Hemocyanin_C PF03723.14 EGG23792.1 - 1.9e-31 109.3 0.0 3e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Hemocyanin, ig-like domain Tyrosinase PF00264.20 EGG23792.1 - 0.0018 18.6 0.8 0.004 17.5 0.8 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase CBM32 PF18344.1 EGG23793.1 - 0.053 13.4 0.1 0.19 11.6 0.1 2.0 1 0 0 1 1 1 0 Carbohydrate binding module family 32 Peptidase_S28 PF05577.12 EGG23794.1 - 3e-120 402.0 7.2 4e-120 401.6 7.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 EGG23794.1 - 0.0064 15.2 0.3 0.011 14.4 0.3 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Cofilin_ADF PF00241.20 EGG23795.1 - 1.5e-33 115.1 0.0 4e-16 58.9 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Tex_N PF09371.10 EGG23796.1 - 0.013 15.2 0.8 0.013 15.2 0.8 1.9 2 0 0 2 2 2 0 Tex-like protein N-terminal domain zf-Di19 PF05605.12 EGG23796.1 - 0.018 15.3 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF3810 PF12725.7 EGG23796.1 - 0.031 13.6 0.6 0.091 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Pkinase_Tyr PF07714.17 EGG23797.1 - 2.6e-56 190.8 0.0 4e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG23797.1 - 1.2e-47 162.5 0.0 2.1e-47 161.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SAM_1 PF00536.30 EGG23797.1 - 5.6e-10 39.5 0.2 1.7e-09 38.0 0.2 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGG23797.1 - 3e-07 30.4 0.1 6.6e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_2 PF12796.7 EGG23797.1 - 1.1e-06 29.1 0.3 4e-05 24.1 0.3 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG23797.1 - 1.6e-06 28.2 0.0 5.3e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG23797.1 - 1.8e-05 25.2 0.1 0.0018 18.8 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Haspin_kinase PF12330.8 EGG23797.1 - 2.8e-05 23.2 0.5 0.011 14.7 0.0 2.6 3 0 0 3 3 3 2 Haspin like kinase domain Ank_3 PF13606.6 EGG23797.1 - 0.00011 22.4 0.2 0.0045 17.4 0.0 3.4 3 1 1 4 4 3 1 Ankyrin repeat SAM_4 PF18017.1 EGG23797.1 - 0.0002 21.3 0.0 0.00055 19.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank PF00023.30 EGG23797.1 - 0.00024 21.4 0.0 0.0036 17.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Sec3_C PF09763.9 EGG23797.1 - 0.0056 15.1 0.7 0.011 14.1 0.7 1.4 1 1 0 1 1 1 1 Exocyst complex component Sec3 RIO1 PF01163.22 EGG23797.1 - 0.01 15.5 0.0 0.078 12.6 0.0 2.4 2 1 0 2 2 2 1 RIO1 family APH PF01636.23 EGG23797.1 - 0.037 13.9 0.1 0.09 12.7 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF764 PF05561.11 EGG23797.1 - 0.13 12.1 0.2 9.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF764) Cys_Met_Meta_PP PF01053.20 EGG23798.1 - 1e-134 448.9 0.0 1.2e-134 448.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGG23798.1 - 2.7e-06 26.6 0.1 6.2e-05 22.1 0.1 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGG23798.1 - 8.3e-05 21.9 0.1 0.00013 21.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SET PF00856.28 EGG23799.1 - 5.7e-08 33.3 0.1 1.9e-07 31.6 0.1 1.9 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 EGG23799.1 - 8.6e-08 31.7 6.0 6.6e-05 22.7 0.7 3.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG23799.1 - 5.2e-06 26.0 7.9 1.6e-05 24.5 1.3 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGG23799.1 - 2.3e-05 24.0 0.8 2.3e-05 24.0 0.8 2.0 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 EGG23799.1 - 6.6e-05 22.8 1.9 6.6e-05 22.8 1.9 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG23799.1 - 0.00062 20.4 0.6 0.014 16.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGG23799.1 - 0.01 16.4 0.6 0.039 14.6 0.6 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG23799.1 - 0.019 14.9 0.8 1.6 8.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG23799.1 - 0.028 14.7 1.4 0.088 13.1 0.4 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGG23799.1 - 0.25 11.9 3.8 0.11 13.0 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SET PF00856.28 EGG23800.1 - 3.4e-09 37.3 0.0 7.7e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 SET domain TPR_1 PF00515.28 EGG23800.1 - 5.6e-09 35.4 5.9 1.1e-05 25.0 1.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG23800.1 - 3.3e-07 29.9 10.9 5.3e-05 23.0 0.6 3.6 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG23800.1 - 4.7e-07 29.4 4.0 2.3e-05 24.0 0.8 2.7 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 EGG23800.1 - 4.5e-06 26.4 2.6 4.8e-05 23.2 1.6 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGG23800.1 - 0.00011 22.7 0.1 0.012 16.4 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG23800.1 - 0.0083 16.4 5.6 0.16 12.3 1.0 3.5 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGG23800.1 - 0.022 15.3 0.9 0.058 13.9 0.5 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG23800.1 - 0.027 15.1 0.7 0.027 15.1 0.7 3.2 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGG23800.1 - 0.052 13.6 1.4 1.2 9.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGG23800.1 - 2.3 8.9 6.3 11 6.7 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat Dynamin_M PF01031.20 EGG23801.1 - 5.2e-104 347.5 0.3 5.2e-104 347.5 0.3 2.0 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EGG23801.1 - 1.3e-59 201.0 0.0 1.3e-59 201.0 0.0 3.1 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 EGG23801.1 - 2.4e-32 110.9 3.0 2.4e-32 110.9 3.0 2.3 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGG23801.1 - 5.2e-05 23.3 0.1 0.00032 20.8 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase TFIIA PF03153.13 EGG23801.1 - 0.0052 16.9 25.3 0.0075 16.3 25.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FeoB_N PF02421.18 EGG23801.1 - 0.11 12.0 2.0 15 5.1 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B SPX PF03105.19 EGG23801.1 - 0.18 11.7 18.2 0.29 11.0 18.2 1.2 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 EGG23801.1 - 2.3 6.8 16.5 3.7 6.1 16.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glyco_hydro_63 PF03200.16 EGG23802.1 - 2.3e-108 363.1 5.8 6.4e-108 361.6 5.8 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EGG23802.1 - 5.4e-47 160.8 5.0 5.4e-47 160.8 5.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain PA14 PF07691.12 EGG23802.1 - 1.4e-06 28.2 1.4 5.1e-06 26.4 0.1 2.3 2 0 0 2 2 2 1 PA14 domain zf-A20 PF01754.16 EGG23803.1 - 2.3e-12 46.6 7.9 2.3e-12 46.6 7.9 2.2 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 EGG23803.1 - 5e-10 39.4 10.5 5e-10 39.4 10.5 2.6 2 1 0 2 2 2 1 AN1-like Zinc finger PSCyt3 PF07627.11 EGG23803.1 - 0.15 12.3 1.1 0.32 11.3 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) XRCC1_N PF01834.16 EGG23804.1 - 7.8e-51 172.0 1.1 1.3e-50 171.2 1.1 1.4 1 0 0 1 1 1 1 XRCC1 N terminal domain BRCT PF00533.26 EGG23804.1 - 3e-16 59.6 0.2 4.9e-09 36.5 0.0 3.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGG23804.1 - 1.6e-14 54.0 0.1 1.8e-07 31.4 0.1 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EGG23804.1 - 1.7e-09 37.8 0.4 0.0015 18.8 0.0 3.0 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 EGG23804.1 - 6.1e-08 32.5 0.0 1.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain Abhydrolase_1 PF00561.20 EGG23805.1 - 3.9e-26 92.2 0.2 6.3e-26 91.6 0.2 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG23805.1 - 6.2e-09 36.8 0.0 7.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG23805.1 - 1.5e-08 34.2 0.0 3.8e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EGG23805.1 - 0.045 13.4 0.1 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) EHN PF06441.12 EGG23805.1 - 0.049 14.0 0.1 1.2 9.6 0.0 2.7 2 1 0 2 2 2 0 Epoxide hydrolase N terminus Hira PF07569.11 EGG23806.1 - 0.75 9.5 10.1 0.1 12.3 5.4 2.0 2 0 0 2 2 2 0 TUP1-like enhancer of split An_peroxidase PF03098.15 EGG23807.1 - 1.9e-135 452.4 0.0 2.2e-135 452.2 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase E1-E2_ATPase PF00122.20 EGG23809.1 - 7.6e-47 159.2 1.5 7.6e-47 159.2 1.5 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGG23809.1 - 5.6e-42 143.5 2.3 5.6e-42 143.5 2.3 2.8 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGG23809.1 - 1e-20 74.9 0.3 7.8e-18 65.5 0.3 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGG23809.1 - 2.2e-20 72.5 0.0 5.2e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGG23809.1 - 9.9e-20 70.0 0.0 2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGG23809.1 - 7e-05 22.7 7.9 0.00058 19.7 0.5 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG23809.1 - 0.11 12.9 0.0 1.2 9.5 0.0 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase AIG1 PF04548.16 EGG23810.1 - 1.9e-21 76.4 0.0 4.2e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 EGG23810.1 - 4.4e-10 39.6 0.0 9.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG23810.1 - 3.9e-05 23.6 0.1 8.1e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase Miga PF10265.9 EGG23810.1 - 4.1e-05 22.8 6.1 5.5e-05 22.3 6.1 1.1 1 0 0 1 1 1 1 Mitoguardin Septin PF00735.18 EGG23810.1 - 0.00065 19.1 0.2 0.0021 17.4 0.2 1.8 1 1 0 1 1 1 1 Septin AAA_16 PF13191.6 EGG23810.1 - 0.0018 18.7 0.0 0.0057 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 EGG23810.1 - 0.018 15.1 0.1 0.018 15.1 0.1 3.5 2 2 1 3 3 2 0 Dynamin family FeoB_N PF02421.18 EGG23810.1 - 0.019 14.5 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF815 PF05673.13 EGG23810.1 - 0.023 13.9 0.2 0.058 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 EGG23810.1 - 0.03 14.8 1.5 0.081 13.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter T2SSE PF00437.20 EGG23810.1 - 0.041 13.0 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 EGG23810.1 - 0.041 13.4 0.0 0.041 13.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EGG23810.1 - 0.054 12.9 0.4 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 EGG23810.1 - 0.054 12.8 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Sigma54_activat PF00158.26 EGG23810.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGG23810.1 - 0.2 11.4 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Peptidase_S64 PF08192.11 EGG23810.1 - 2.5 6.5 12.3 3.2 6.1 12.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.9 EGG23810.1 - 2.7 6.4 13.9 3.5 6.1 13.9 1.1 1 0 0 1 1 1 0 Macoilin family Tmemb_cc2 PF10267.9 EGG23810.1 - 5.4 6.1 10.0 8.1 5.5 10.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Apt1 PF10351.9 EGG23810.1 - 5.4 5.8 16.7 7.3 5.3 16.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM76 PF16046.5 EGG23810.1 - 6.1 6.1 12.9 9.8 5.4 12.9 1.2 1 0 0 1 1 1 0 FAM76 protein Tet_JBP PF12851.7 EGG23811.1 - 0.08 12.3 0.0 0.088 12.1 0.0 1.0 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Meth_synt_2 PF01717.18 EGG23812.1 - 7.6e-145 482.2 0.0 5.7e-141 469.5 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EGG23812.1 - 3.3e-103 345.5 0.1 3.3e-97 325.8 0.1 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain La PF05383.17 EGG23812.1 - 0.02 14.9 0.0 0.079 13.0 0.0 2.1 1 0 0 1 1 1 0 La domain SHOCT PF09851.9 EGG23812.1 - 0.1 12.3 0.6 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 Short C-terminal domain Branch PF02485.21 EGG23813.1 - 9e-08 31.9 1.8 4.2e-07 29.7 1.8 2.2 1 1 0 1 1 1 1 Core-2/I-Branching enzyme WD40 PF00400.32 EGG23816.1 - 1.1e-48 162.1 35.4 2.6e-06 28.1 1.1 11.6 11 0 0 11 11 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG23816.1 - 8.7e-24 83.6 4.1 0.002 18.4 0.0 8.4 3 3 4 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain DUF4062 PF13271.6 EGG23816.1 - 6.6e-15 55.3 0.0 2.1e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) AAA_16 PF13191.6 EGG23816.1 - 3.2e-10 40.7 0.0 1.8e-09 38.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGG23816.1 - 1.1e-09 38.6 0.0 2.9e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EGG23816.1 - 2.5e-09 37.2 0.0 5.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EGG23816.1 - 1.6e-05 25.0 0.0 5.4e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea APAF1_C PF17908.1 EGG23816.1 - 2.6e-05 24.2 0.2 0.00026 21.0 0.2 2.5 1 1 0 1 1 1 1 APAF-1 helical domain AAA PF00004.29 EGG23816.1 - 0.00013 22.4 0.1 0.00055 20.4 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 EGG23816.1 - 0.0046 17.1 0.0 0.072 13.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain KAP_NTPase PF07693.14 EGG23816.1 - 0.019 14.2 0.9 0.12 11.6 0.9 2.1 1 1 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.22 EGG23816.1 - 0.046 14.1 0.5 0.38 11.1 0.0 2.8 3 0 0 3 3 3 0 RNA helicase ThiS-like PF14453.6 EGG23816.1 - 0.053 13.6 0.0 0.19 11.8 0.0 2.0 1 0 0 1 1 1 0 ThiS-like ubiquitin AAA_24 PF13479.6 EGG23816.1 - 0.11 12.2 0.2 1.5 8.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain Peptidase_S10 PF00450.22 EGG23817.1 - 1.2e-108 364.2 7.3 1.7e-108 363.8 7.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3012 PF11216.8 EGG23817.1 - 0.19 11.8 0.5 0.4 10.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) zf-C3HC4_3 PF13920.6 EGG23820.1 - 3.6e-13 49.2 6.2 6.1e-13 48.4 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG23820.1 - 1.2e-06 28.2 6.9 2.4e-06 27.3 6.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGG23820.1 - 0.0011 19.3 8.9 0.0027 18.0 8.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGG23820.1 - 0.0029 17.5 7.9 0.0058 16.6 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EGG23820.1 - 0.0086 15.8 7.2 0.02 14.7 7.2 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 EGG23820.1 - 0.067 13.0 7.9 0.14 12.0 7.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 EGG23820.1 - 0.26 11.0 9.4 0.14 11.8 5.4 2.5 2 0 0 2 2 2 0 P-11 zinc finger PhnA_Zn_Ribbon PF08274.12 EGG23820.1 - 0.4 10.7 3.3 26 4.9 1.9 3.0 2 1 0 2 2 2 0 PhnA Zinc-Ribbon RPN2_C PF18004.1 EGG23821.1 - 1.5e-47 161.4 11.9 2.7e-47 160.7 11.9 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EGG23821.1 - 1.5e-36 123.0 28.3 5.6e-07 29.7 0.1 9.3 10 0 0 10 10 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGG23821.1 - 4e-14 52.8 0.0 7e-10 39.2 0.0 3.7 2 1 2 4 4 4 2 HEAT repeats HEAT PF02985.22 EGG23821.1 - 0.0017 18.4 0.1 4.1 7.9 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat DUF4887 PF16228.5 EGG23821.1 - 0.013 15.7 11.9 0.023 14.9 11.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) Clathrin_H_link PF13838.6 EGG23821.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 Clathrin-H-link RNase_H2_suC PF08615.11 EGG23821.1 - 0.037 14.2 0.8 0.1 12.7 0.8 1.7 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) IBN_N PF03810.19 EGG23821.1 - 0.052 13.5 0.0 28 4.7 0.0 3.7 3 0 0 3 3 3 0 Importin-beta N-terminal domain RAB3GAP2_C PF14656.6 EGG23821.1 - 0.1 10.8 1.5 0.18 10.0 1.5 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DDHD PF02862.17 EGG23821.1 - 0.14 12.3 0.6 0.25 11.5 0.6 1.3 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.8 EGG23821.1 - 0.2 10.4 7.1 0.31 9.8 7.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 EGG23821.1 - 0.62 8.8 2.6 0.96 8.1 2.6 1.2 1 0 0 1 1 1 0 Presenilin TAP42 PF04177.12 EGG23821.1 - 1.2 8.2 11.3 1.9 7.5 11.3 1.2 1 0 0 1 1 1 0 TAP42-like family RR_TM4-6 PF06459.12 EGG23821.1 - 1.3 8.8 11.2 2.2 8.1 11.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1840 PF08895.11 EGG23821.1 - 1.3 9.4 5.9 3.1 8.2 5.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) FAM176 PF14851.6 EGG23821.1 - 3.1 7.5 8.0 8.9 6.0 8.0 1.7 1 0 0 1 1 1 0 FAM176 family Trypan_PARP PF05887.11 EGG23821.1 - 3.3 7.7 10.1 7.8 6.5 10.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AAR2 PF05282.11 EGG23821.1 - 3.6 6.9 6.5 0.26 10.6 1.2 1.7 2 0 0 2 2 2 0 AAR2 protein PBP_sp32 PF07222.12 EGG23821.1 - 5.6 6.3 8.8 9.3 5.6 8.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CBS PF00571.28 EGG23822.1 - 3.5e-28 97.8 5.9 3.5e-10 40.2 0.0 4.7 5 0 0 5 5 5 4 CBS domain LysM PF01476.20 EGG23823.1 - 2.3e-06 27.5 0.2 2.3e-06 27.5 0.2 2.4 2 0 0 2 2 2 1 LysM domain RRP36 PF06102.12 EGG23824.1 - 9.5e-44 149.3 20.8 9.5e-44 149.3 20.8 2.5 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 zf-MYND PF01753.18 EGG23825.1 - 5e-09 36.1 9.0 9.2e-09 35.3 9.0 1.5 1 0 0 1 1 1 1 MYND finger CTK3 PF12243.8 EGG23825.1 - 0.15 12.1 0.1 0.15 12.1 0.1 1.7 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 zf-C6H2 PF15801.5 EGG23825.1 - 3.7 7.9 8.6 6.7 7.1 8.6 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Pro-kuma_activ PF09286.11 EGG23826.1 - 4.1e-30 105.0 0.1 7.1e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGG23826.1 - 9.8e-06 25.0 1.0 1.9e-05 24.1 0.9 1.7 1 1 0 1 1 1 1 Subtilase family bZIP_1 PF00170.21 EGG23827.1 - 1.3e-12 47.6 13.6 1.3e-12 47.6 13.6 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGG23827.1 - 2.1e-09 37.3 12.1 2.1e-09 37.3 12.1 2.9 3 1 1 4 4 4 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGG23827.1 - 7.4e-06 26.4 6.3 7.4e-06 26.4 6.3 3.9 4 0 0 4 4 4 1 bZIP Maf transcription factor AMP-binding PF00501.28 EGG23828.1 - 1.4e-81 274.3 0.0 1.7e-81 274.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGG23828.1 - 1.6e-14 54.6 0.1 3.1e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YjcB PF15940.5 EGG23828.1 - 0.0078 16.4 0.1 0.025 14.7 0.1 1.8 2 0 0 2 2 2 1 Family of unknown function GH3 PF03321.13 EGG23828.1 - 0.013 14.3 0.1 0.14 11.0 0.1 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter TruD PF01142.18 EGG23829.1 - 1.4e-79 267.9 4.9 3.4e-74 250.2 1.9 3.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) MFS_1 PF07690.16 EGG23830.1 - 7e-13 48.2 20.2 7e-13 48.2 20.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGG23830.1 - 0.19 10.2 17.9 0.081 11.5 0.6 2.7 3 0 0 3 3 3 0 MFS/sugar transport protein Actin PF00022.19 EGG23832.1 - 1.5e-151 504.6 0.0 4.8e-151 503.0 0.0 1.6 1 1 0 1 1 1 1 Actin FAD_binding_1 PF00667.20 EGG23834.1 - 1.3e-38 132.9 0.7 3.1e-38 131.6 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 EGG23834.1 - 1.4e-28 99.9 0.2 4.2e-28 98.4 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 EGG23834.1 - 5.1e-18 65.7 0.0 1.2e-17 64.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EGG23834.1 - 0.0017 18.6 0.0 0.0047 17.2 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.12 EGG23834.1 - 0.087 13.0 0.1 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Proteasome PF00227.26 EGG23836.1 - 2.6e-42 144.5 0.0 2.9e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF2722 PF10846.8 EGG23837.1 - 0.003 16.6 2.5 0.0037 16.3 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TMEM51 PF15345.6 EGG23837.1 - 0.019 14.8 2.3 0.039 13.8 2.3 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 F-box-like PF12937.7 EGG23837.1 - 0.023 14.6 0.4 0.067 13.1 0.1 1.9 2 0 0 2 2 2 0 F-box-like Connexin PF00029.19 EGG23837.1 - 0.092 12.5 3.6 0.15 11.8 3.6 1.3 1 0 0 1 1 1 0 Connexin CDT1_C PF16679.5 EGG23837.1 - 0.11 13.0 3.8 0.6 10.6 3.8 2.4 1 1 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain F-box PF00646.33 EGG23837.1 - 0.11 12.4 0.2 0.33 10.9 0.2 1.8 1 0 0 1 1 1 0 F-box domain DUF3464 PF11947.8 EGG23837.1 - 0.22 11.3 6.0 0.35 10.6 6.0 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 FtsK_alpha PF17854.1 EGG23837.1 - 0.38 10.9 2.5 1 9.5 2.5 1.7 1 0 0 1 1 1 0 FtsK alpha domain DUF4519 PF15012.6 EGG23837.1 - 0.77 10.0 7.1 2 8.7 7.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Med3 PF11593.8 EGG23837.1 - 0.8 8.8 8.5 1.2 8.3 8.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1631 PF07793.11 EGG23837.1 - 1.9 6.8 8.1 2.9 6.2 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) MAS20 PF02064.15 EGG23837.1 - 5.8 7.0 11.0 3.4 7.8 6.5 2.5 3 0 0 3 3 3 0 MAS20 protein import receptor PseudoU_synth_2 PF00849.22 EGG23838.1 - 2e-27 96.2 0.1 1.2e-26 93.7 0.0 2.2 2 0 0 2 2 2 1 RNA pseudouridylate synthase Mod_r PF07200.13 EGG23838.1 - 3.2e-25 88.9 19.5 3.2e-25 88.9 19.5 2.5 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein TFIIA PF03153.13 EGG23838.1 - 0.00029 21.0 12.6 0.00045 20.3 12.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 EGG23838.1 - 1.2 8.7 10.8 2.2 7.8 10.8 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Med11 PF10280.9 EGG23839.1 - 4.3e-10 40.2 0.2 4.3e-10 40.2 0.2 2.1 1 1 1 2 2 2 1 Mediator complex protein SNARE PF05739.19 EGG23839.1 - 0.29 11.2 0.2 0.29 11.2 0.2 1.9 2 0 0 2 2 2 0 SNARE domain Rrp15p PF07890.12 EGG23841.1 - 1.9e-18 67.1 11.3 1.9e-18 67.1 11.3 3.7 2 2 1 3 3 3 1 Rrp15p AF-4 PF05110.13 EGG23841.1 - 0.032 12.4 46.0 0.016 13.4 17.2 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein CdiI_2 PF18593.1 EGG23841.1 - 0.039 14.6 0.2 0.039 14.6 0.2 2.4 3 0 0 3 3 3 0 CdiI immunity protein UQ_con PF00179.26 EGG23842.1 - 6.8e-51 171.6 0.1 7.7e-51 171.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Orf78 PF06024.12 EGG23843.1 - 0.0066 16.7 2.7 1.6 9.0 0.2 2.3 2 0 0 2 2 2 2 Orf78 (ac78) TMEM117 PF15113.6 EGG23843.1 - 0.12 11.3 1.2 0.12 11.2 0.2 1.5 2 0 0 2 2 2 0 TMEM117 protein family Reo_P9 PF06043.11 EGG23843.1 - 0.53 9.7 10.1 0.25 10.7 2.6 2.3 2 0 0 2 2 2 0 Reovirus P9-like family Pkinase PF00069.25 EGG23844.1 - 6.6e-66 222.4 0.0 9.4e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23844.1 - 6.6e-20 71.5 0.4 1.4e-19 70.4 0.0 1.7 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG23844.1 - 0.00085 18.7 0.0 0.0033 16.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Choline_kinase PF01633.20 EGG23844.1 - 0.0097 15.5 0.3 0.017 14.7 0.3 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGG23844.1 - 0.049 13.6 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1168 PF06658.12 EGG23845.1 - 9.6e-27 93.5 23.6 1.2e-26 93.1 23.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) UPF0560 PF10577.9 EGG23845.1 - 0.2 10.1 13.5 0.21 10.0 13.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3314 PF11771.8 EGG23845.1 - 0.31 11.2 3.3 0.14 12.3 1.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3314) Band_3_cyto PF07565.13 EGG23845.1 - 1.1 9.0 8.0 1.4 8.7 8.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Efg1 PF10153.9 EGG23845.1 - 7.9 6.9 22.2 13 6.1 22.2 1.4 1 1 0 1 1 1 0 rRNA-processing protein Efg1 LMBR1 PF04791.16 EGG23845.1 - 9.7 5.0 6.4 9.8 4.9 6.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CPSase_L_D2 PF02786.17 EGG23846.1 - 1.3e-116 387.5 0.9 3.3e-86 288.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EGG23846.1 - 2.9e-46 156.5 0.0 7.9e-46 155.0 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 EGG23846.1 - 1e-45 155.4 0.0 2.6e-45 154.1 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 EGG23846.1 - 1.5e-42 145.5 0.0 3e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 EGG23846.1 - 1.2e-39 135.4 0.2 7.9e-39 132.8 0.1 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EGG23846.1 - 5.1e-29 101.4 0.1 1.6e-28 99.8 0.1 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 EGG23846.1 - 1.5e-23 83.4 1.8 4.9e-12 45.8 0.3 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGG23846.1 - 2.5e-18 66.2 0.1 1.7e-10 40.7 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 EGG23846.1 - 6.6e-16 58.3 0.0 3.7e-15 55.9 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain ATPgrasp_Ter PF15632.6 EGG23846.1 - 3e-11 43.2 0.1 5.1e-05 23.0 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Amidohydro_1 PF01979.20 EGG23846.1 - 5.1e-11 42.5 0.5 7.9e-10 38.6 0.2 2.7 2 1 0 2 2 2 1 Amidohydrolase family ATP-grasp_3 PF02655.14 EGG23846.1 - 3.6e-10 40.1 0.9 3.7e-05 23.8 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 EGG23846.1 - 0.0035 17.1 0.4 0.25 11.1 0.4 2.4 1 1 0 1 1 1 1 Peptidase C26 PfkB PF00294.24 EGG23847.1 - 6.8e-47 160.2 0.4 7.9e-47 160.0 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EGG23847.1 - 0.0094 15.4 0.2 0.068 12.5 0.0 2.0 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase OB_NTP_bind PF07717.16 EGG23848.1 - 2.2e-16 59.9 0.0 5.1e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EGG23848.1 - 8e-16 58.3 0.0 2e-15 57.0 0.0 1.7 1 1 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGG23848.1 - 1.6e-14 54.2 0.3 4.3e-14 52.8 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGG23848.1 - 6.3e-06 26.5 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EGG23848.1 - 8.2e-06 25.7 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EGG23848.1 - 5.6e-05 23.5 0.1 0.00012 22.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG23848.1 - 0.0032 17.2 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGG23848.1 - 0.015 14.4 0.3 0.2 10.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Flavi_DEAD PF07652.14 EGG23848.1 - 0.019 15.0 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 EGG23848.1 - 0.061 13.8 0.1 0.38 11.3 0.1 2.3 1 1 1 2 2 2 0 ABC transporter AAA_7 PF12775.7 EGG23848.1 - 0.062 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EGG23848.1 - 0.14 11.4 0.1 0.26 10.6 0.1 1.4 1 0 0 1 1 1 0 KaiC Fcf1 PF04900.12 EGG23849.1 - 3.3e-19 69.1 0.1 9.4e-19 67.7 0.0 1.8 2 0 0 2 2 2 1 Fcf1 PH_13 PF16652.5 EGG23849.1 - 0.011 15.6 3.2 0.015 15.1 1.4 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Tfb2_C PF18307.1 EGG23849.1 - 0.12 12.8 0.7 0.7 10.4 0.1 2.5 2 1 1 3 3 3 0 Transcription factor Tfb2 (p52) C-terminal domain Glycos_transf_1 PF00534.20 EGG23851.1 - 1.1e-38 132.4 0.0 1.7e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGG23851.1 - 1.3e-17 64.5 0.0 2e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGG23851.1 - 9.4e-16 58.3 0.0 1.7e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGG23851.1 - 9.4e-08 32.7 0.0 1.5e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 EGG23851.1 - 0.2 11.7 1.7 7.4 6.6 0.1 3.0 1 1 1 2 2 2 0 ALG11 mannosyltransferase N-terminus DUF4611 PF15387.6 EGG23852.1 - 0.084 13.1 1.0 0.19 11.9 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF592 PF04574.13 EGG23852.1 - 0.15 11.8 6.3 0.84 9.4 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF592) GST_N_3 PF13417.6 EGG23853.1 - 4.8e-13 49.3 0.0 8.7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGG23853.1 - 5e-12 46.0 0.0 1.3e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGG23853.1 - 3.3e-10 39.9 0.1 5.1e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG23853.1 - 3.8e-10 39.8 0.0 6.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGG23853.1 - 4.3e-10 39.8 0.0 6.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGG23853.1 - 3.5e-07 30.3 0.2 7.5e-07 29.3 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_2 PF00891.18 EGG23854.1 - 8.5e-46 155.9 0.0 1.3e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGG23854.1 - 7.2e-10 38.7 0.0 3.8e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_31 PF13847.6 EGG23854.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Amidohydro_1 PF01979.20 EGG23855.1 - 5e-31 108.3 0.3 8.2e-31 107.6 0.3 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGG23855.1 - 1.5e-11 44.4 3.1 5.3e-05 22.9 0.3 2.6 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 EGG23855.1 - 2.5e-07 30.8 0.0 3.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase RNB PF00773.19 EGG23856.1 - 3.4e-67 227.1 0.1 3.5e-51 174.5 0.0 2.9 3 1 1 4 4 4 2 RNB domain OB_Dis3 PF17849.1 EGG23856.1 - 6.3e-21 74.2 0.0 1.4e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 EGG23856.1 - 5.4e-08 32.7 0.0 5.4e-08 32.7 0.0 3.4 1 1 2 3 3 3 1 Rrp44-like cold shock domain Dis3l2_C_term PF17877.1 EGG23856.1 - 0.00063 20.0 0.0 0.00063 20.0 0.0 4.9 5 1 0 5 5 5 1 DIS3-like exonuclease 2 C terminal MFS_1 PF07690.16 EGG23859.1 - 2e-22 79.6 15.6 2.8e-22 79.1 15.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG23859.1 - 6.6e-08 31.8 12.6 5e-07 28.9 12.6 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter SPRY PF00622.28 EGG23860.1 - 8.2e-14 51.8 5.6 1e-07 32.1 0.9 3.3 3 0 0 3 3 3 2 SPRY domain PHD PF00628.29 EGG23860.1 - 8.2e-05 22.4 5.3 0.00018 21.4 5.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 EGG23860.1 - 0.31 11.2 2.6 1.1 9.4 2.6 2.0 1 0 0 1 1 1 0 PHD-finger SPC25 PF06703.11 EGG23861.1 - 1.5e-34 119.2 0.1 1.8e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) BPD_transp_2 PF02653.16 EGG23861.1 - 0.004 16.4 0.0 0.0047 16.1 0.0 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component TRAPPC9-Trs120 PF08626.11 EGG23862.1 - 9.8e-110 367.7 16.3 2.4e-75 253.8 11.5 3.0 1 1 2 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 EGG23862.1 - 0.0019 18.5 0.0 0.35 11.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGG23862.1 - 0.093 12.9 0.1 7.4 7.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CAF1C_H4-bd PF12265.8 EGG23863.1 - 2.6e-28 98.1 3.3 8e-28 96.5 0.9 2.8 3 1 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGG23863.1 - 9.1e-24 83.3 18.5 1.2e-06 29.1 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG23863.1 - 0.0019 18.5 2.4 0.54 10.6 0.0 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Acyl-CoA_dh_1 PF00441.24 EGG23864.1 - 6.6e-26 91.3 0.0 1.2e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 EGG23864.1 - 4.7e-20 72.1 0.0 7.1e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGG23864.1 - 4e-12 46.6 0.0 7.5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGG23864.1 - 1e-11 44.9 0.1 1.9e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Peptidase_M20 PF01546.28 EGG23865.1 - 2.1e-29 102.7 0.0 3.3e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGG23865.1 - 7.9e-17 61.1 0.0 2.2e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Methyltransf_16 PF10294.9 EGG23865.1 - 1.4e-14 54.2 0.0 1.4e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EGG23865.1 - 8.1e-10 38.7 3.2 2.9e-09 36.9 0.2 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG23865.1 - 1.9e-07 31.7 0.2 6.2e-07 30.0 0.0 2.1 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG23865.1 - 1.1e-06 29.2 0.1 8.9e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG23865.1 - 2.2e-06 27.6 0.2 6.9e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG23865.1 - 1.9e-05 25.3 0.1 1.9e-05 25.3 0.1 2.5 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 EGG23865.1 - 3.3e-05 23.4 0.2 3.3e-05 23.4 0.2 2.1 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 EGG23865.1 - 0.0093 15.6 0.3 0.035 13.7 0.1 2.0 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase NodS PF05401.11 EGG23865.1 - 0.02 14.5 0.1 0.053 13.1 0.0 1.7 2 0 0 2 2 2 0 Nodulation protein S (NodS) MTS PF05175.14 EGG23865.1 - 0.079 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.25 EGG23866.1 - 3.2e-74 249.6 0.2 1.4e-73 247.6 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23866.1 - 6.5e-50 169.8 0.0 1.6e-49 168.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG23866.1 - 5.9e-06 25.3 0.1 5.9e-06 25.3 0.1 2.3 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGG23866.1 - 0.0011 18.4 0.0 0.0031 16.9 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG23866.1 - 0.0017 17.8 0.1 0.0033 16.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGG23866.1 - 0.0036 16.9 0.2 0.0079 15.8 0.2 1.5 1 0 0 1 1 1 1 RIO1 family DUF4820 PF16091.5 EGG23866.1 - 0.0058 16.0 9.0 0.018 14.4 9.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) VF530 PF09905.9 EGG23866.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 DNA-binding protein VF530 Peptidase_M8 PF01457.16 EGG23869.1 - 4.2e-61 207.2 12.4 4.2e-61 207.2 12.4 1.9 2 1 0 2 2 2 1 Leishmanolysin RCDG1 PF15725.5 EGG23869.1 - 0.13 12.7 8.7 0.44 11.0 8.7 1.8 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein cNMPbd_u2 PF16643.5 EGG23869.1 - 4.2 7.8 7.7 9.4 6.7 7.7 1.6 1 1 0 1 1 1 0 Unstructured region on cNMP-binding protein Thioredoxin PF00085.20 EGG23870.1 - 2.3e-24 85.4 0.3 2.8e-23 81.8 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 EGG23870.1 - 0.0021 18.4 3.6 1.2 9.5 0.0 4.1 3 1 2 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGG23870.1 - 0.006 17.0 0.2 0.068 13.6 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain U62_UL91 PF17442.2 EGG23870.1 - 0.048 13.7 0.0 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins Redoxin PF08534.10 EGG23870.1 - 0.11 12.3 1.3 22 4.8 0.1 3.1 3 0 0 3 3 3 0 Redoxin GATA PF00320.27 EGG23871.1 - 2.9e-10 39.6 7.8 2.9e-10 39.6 7.8 1.9 2 0 0 2 2 2 1 GATA zinc finger AT_hook PF02178.19 EGG23871.1 - 0.89 9.6 5.6 2.3 8.4 5.6 1.8 1 0 0 1 1 1 0 AT hook motif NOB1_Zn_bind PF08772.11 EGG23871.1 - 7.3 6.8 9.3 12 6.1 0.0 3.8 4 0 0 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like Pkinase PF00069.25 EGG23873.1 - 2.6e-60 204.0 0.0 4e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23873.1 - 9.8e-40 136.5 0.0 1.6e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG23873.1 - 5.4e-05 22.1 0.0 5.4e-05 22.1 0.0 3.7 2 1 0 2 2 2 1 Fungal protein kinase CBM49 PF09478.10 EGG23874.1 - 8.7e-16 58.0 0.1 1.2e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 EcKinase PF02958.20 EGG23874.1 - 0.034 13.5 0.2 0.041 13.2 0.2 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3439 PF11921.8 EGG23875.1 - 0.34 10.9 4.5 1.3 9.0 4.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4227 PF14004.6 EGG23876.1 - 0.001 19.0 11.5 0.23 11.5 0.2 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF4227) PepSY_TM PF03929.16 EGG23876.1 - 0.004 16.9 7.7 0.15 11.7 0.7 2.2 1 1 1 2 2 2 2 PepSY-associated TM region DHHC PF01529.20 EGG23876.1 - 0.72 10.0 9.7 0.068 13.3 1.9 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase HemY_N PF07219.13 EGG23876.1 - 3.8 7.8 9.8 27 5.0 0.6 3.1 2 1 0 3 3 3 0 HemY protein N-terminus NUDIX PF00293.28 EGG23877.1 - 5.6e-13 49.1 0.0 9.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Ras PF00071.22 EGG23878.1 - 1.1e-53 181.1 0.2 1.5e-53 180.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG23878.1 - 1.3e-27 96.4 0.0 2.2e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG23878.1 - 1.3e-09 37.8 0.0 1.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG23878.1 - 0.00065 19.8 0.0 0.0014 18.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGG23878.1 - 0.0022 17.6 0.0 0.0053 16.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGG23878.1 - 0.077 12.3 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Rhomboid PF01694.22 EGG23879.1 - 3.2e-10 40.2 9.4 4.4e-10 39.8 7.6 2.0 2 1 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 EGG23879.1 - 0.025 15.2 2.9 0.025 15.2 2.9 2.1 2 1 1 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) Pkinase PF00069.25 EGG23880.1 - 2e-24 86.4 0.0 2.9e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23880.1 - 1.1e-13 51.0 0.0 1.7e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG23880.1 - 3.1e-09 36.1 0.1 3.1e-09 36.1 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGG23880.1 - 0.0086 16.0 0.0 0.025 14.5 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EGG23880.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Hamartin PF04388.12 EGG23880.1 - 0.62 8.7 7.3 0.84 8.2 7.3 1.2 1 0 0 1 1 1 0 Hamartin protein PDDEXK_1 PF12705.7 EGG23881.1 - 3.4e-06 27.2 1.7 5.2e-06 26.5 1.5 1.6 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 EGG23881.1 - 0.011 15.8 0.5 0.026 14.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF83 FlaG PF03646.15 EGG23881.1 - 0.055 13.7 3.6 0.37 11.0 3.7 2.3 2 0 0 2 2 2 0 FlaG protein Rad1 PF02144.16 EGG23883.1 - 2.2e-34 118.8 1.9 4.3e-34 117.8 1.9 1.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 SYS1 PF09801.9 EGG23884.1 - 5.4e-47 159.6 10.3 6.4e-47 159.3 10.3 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF4267 PF14087.6 EGG23884.1 - 0.023 14.8 0.5 0.023 14.8 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) DUF3792 PF12670.7 EGG23884.1 - 6.4 7.0 10.7 5.6 7.2 1.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3792) Thioredoxin PF00085.20 EGG23885.1 - 2.3e-22 78.9 0.1 2.7e-22 78.7 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EGG23885.1 - 5.9e-05 23.2 0.0 8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EGG23885.1 - 0.0004 20.7 0.0 0.00051 20.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EGG23885.1 - 0.00041 20.1 0.0 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EGG23885.1 - 0.0021 17.5 0.1 0.0024 17.3 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EGG23885.1 - 0.0022 17.9 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family NTS_2 PF15448.6 EGG23885.1 - 0.004 17.5 0.2 0.014 15.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal segments of P. falciparum erythrocyte membrane protein Redoxin PF08534.10 EGG23885.1 - 0.0078 15.9 0.1 0.012 15.4 0.1 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 EGG23885.1 - 0.012 16.0 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.24 EGG23885.1 - 0.03 14.6 0.1 0.047 13.9 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin CHB_HEX_C_1 PF13290.6 EGG23885.1 - 0.17 11.9 0.8 6.5 6.9 0.1 2.2 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain Cpn60_TCP1 PF00118.24 EGG23886.1 - 6.1e-60 203.2 1.9 2.8e-59 201.1 0.8 2.1 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Ribosomal_L24e PF01246.20 EGG23887.1 - 5.1e-10 39.4 1.8 6.3e-10 39.1 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e FUR PF01475.19 EGG23887.1 - 0.02 15.1 0.2 0.026 14.7 0.2 1.2 1 0 0 1 1 1 0 Ferric uptake regulator family DUF775 PF05603.12 EGG23887.1 - 0.18 11.3 2.6 0.2 11.2 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) MADF_DNA_bdg PF10545.9 EGG23887.1 - 1.1 9.6 6.0 0.92 9.9 2.4 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Ribosomal_S8e PF01201.22 EGG23888.1 - 7.3e-46 155.7 0.9 1e-45 155.2 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e ECSCR PF15820.5 EGG23889.1 - 0.0035 17.2 1.6 0.15 11.9 0.1 2.3 2 0 0 2 2 2 2 Endothelial cell-specific chemotaxis regulator Claudin_3 PF06653.11 EGG23889.1 - 0.0066 16.4 2.1 0.88 9.5 0.2 2.2 2 0 0 2 2 2 2 Tight junction protein, Claudin-like Cadherin_C_2 PF16492.5 EGG23889.1 - 0.069 13.9 3.6 5.4 7.8 0.8 2.5 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal PPR_2 PF13041.6 EGG23890.1 - 2.4e-12 46.8 9.7 0.0015 18.6 0.2 8.4 7 2 2 9 9 9 5 PPR repeat family PPR PF01535.20 EGG23890.1 - 3.6e-11 42.5 6.4 0.64 10.4 0.1 8.4 8 0 0 8 8 8 3 PPR repeat PPR_long PF17177.4 EGG23890.1 - 2.9e-09 36.6 0.4 1e-06 28.3 0.2 3.1 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EGG23890.1 - 2.5e-06 27.5 7.5 3.9 7.6 0.1 7.7 7 2 3 10 10 10 4 Pentatricopeptide repeat domain TPR_7 PF13176.6 EGG23890.1 - 0.11 12.6 0.0 9.5 6.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PLAC8 PF04749.17 EGG23891.1 - 3.4e-10 40.8 18.1 5e-10 40.3 18.1 1.4 1 0 0 1 1 1 1 PLAC8 family CRAL_TRIO PF00650.20 EGG23892.1 - 2.1e-28 99.0 0.2 3.3e-28 98.4 0.2 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 EGG23892.1 - 1.8e-07 31.7 3.0 0.00014 22.4 0.1 2.8 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 EGG23892.1 - 3.4e-05 23.9 0.3 8e-05 22.8 0.3 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGG23892.1 - 0.0074 16.5 0.3 0.015 15.4 0.3 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain EMP24_GP25L PF01105.24 EGG23892.1 - 0.069 13.1 2.0 0.11 12.4 1.3 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD YflT PF11181.8 EGG23892.1 - 0.087 13.3 0.2 0.93 10.0 0.0 2.3 1 1 1 2 2 2 0 Heat induced stress protein YflT Ank_2 PF12796.7 EGG23894.1 - 3e-44 149.5 5.4 9.3e-13 48.6 0.2 3.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG23894.1 - 8.2e-33 112.4 13.4 2.6e-11 43.8 0.4 4.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG23894.1 - 3.1e-32 110.2 3.4 1.6e-08 34.7 0.1 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EGG23894.1 - 1.3e-27 95.0 3.6 4e-09 36.5 0.2 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EGG23894.1 - 3e-24 82.5 0.9 7.1e-07 29.1 0.1 5.0 4 0 0 4 4 4 4 Ankyrin repeat IBR PF01485.21 EGG23895.1 - 9.7e-13 48.1 26.4 1.5e-11 44.3 5.8 3.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RhoGEF PF00621.20 EGG23897.1 - 2.7e-38 132.0 6.3 5.4e-38 131.1 6.3 1.5 1 0 0 1 1 1 1 RhoGEF domain COMM_domain PF07258.14 EGG23897.1 - 2.6e-17 62.7 0.0 5.8e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 COMM domain MalF_P2 PF14785.6 EGG23897.1 - 0.093 12.7 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Pullulanase_Ins PF18494.1 EGG23897.1 - 1 9.9 3.9 16 6.1 0.3 2.7 2 0 0 2 2 2 0 Pullulanase Ins domain WD40 PF00400.32 EGG23898.1 - 1.7e-38 129.9 14.0 3.6e-09 37.1 0.3 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG23898.1 - 1.2e-14 54.3 0.6 0.01 16.1 0.0 5.9 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGG23898.1 - 5.1e-08 33.0 0.2 0.00056 19.8 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EGG23898.1 - 0.00017 20.8 0.1 0.076 12.0 0.1 2.3 1 1 0 2 2 2 2 Coatomer WD associated region Ge1_WD40 PF16529.5 EGG23898.1 - 0.00026 20.0 0.0 0.23 10.4 0.0 3.8 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGG23898.1 - 0.00027 19.7 1.1 0.067 11.8 0.4 3.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 EGG23898.1 - 0.00072 19.0 0.1 0.036 13.4 0.1 2.5 1 1 1 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 EGG23898.1 - 0.016 15.6 0.4 20 5.8 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain Kelch_6 PF13964.6 EGG23898.1 - 0.041 14.2 0.3 11 6.5 0.0 3.6 3 0 0 3 3 3 0 Kelch motif PQQ PF01011.21 EGG23898.1 - 0.26 11.3 0.9 4.2 7.5 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat Pkinase_Tyr PF07714.17 EGG23899.1 - 8.7e-59 198.9 0.0 1.7e-58 198.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG23899.1 - 2.4e-50 171.3 1.5 2.9e-50 171.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 EGG23899.1 - 1.3e-12 47.7 0.1 4.9e-12 45.8 0.1 2.0 1 0 0 1 1 1 1 SH2 domain APH PF01636.23 EGG23899.1 - 0.018 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family TFIIA PF03153.13 EGG23899.1 - 0.034 14.1 24.8 0.069 13.1 24.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC1 PF03109.16 EGG23899.1 - 0.038 14.2 0.0 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 ABC1 family Dam PF05869.11 EGG23899.1 - 0.086 12.4 0.1 0.086 12.4 0.1 1.9 2 0 0 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) Pkinase_fungal PF17667.1 EGG23899.1 - 0.19 10.5 10.4 0.84 8.3 10.4 2.0 1 1 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 EGG23899.1 - 0.22 11.1 0.0 0.22 11.1 0.0 3.0 3 1 0 3 3 3 0 Choline/ethanolamine kinase SOBP PF15279.6 EGG23899.1 - 0.23 12.0 26.2 0.44 11.1 26.2 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein SH2_2 PF14633.6 EGG23899.1 - 0.26 10.7 10.2 0.94 8.8 0.0 3.1 3 0 0 3 3 3 0 SH2 domain SR-25 PF10500.9 EGG23899.1 - 0.29 10.7 20.5 0.66 9.6 20.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hamartin PF04388.12 EGG23899.1 - 2 6.9 24.9 3.2 6.3 24.9 1.2 1 0 0 1 1 1 0 Hamartin protein THRAP3_BCLAF1 PF15440.6 EGG23899.1 - 3.8 6.4 31.6 5.7 5.8 31.6 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family PA26 PF04636.13 EGG23899.1 - 5.9 5.7 10.6 10 4.9 10.6 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GREB1 PF15782.5 EGG23899.1 - 7.8 3.5 23.1 11 3.0 23.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Fz PF01392.22 EGG23902.1 - 0.0012 19.5 4.5 0.0022 18.6 4.5 1.5 1 0 0 1 1 1 1 Fz domain PAP_assoc PF03828.19 EGG23903.1 - 3.6e-21 75.1 0.1 1.2e-20 73.4 0.1 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGG23903.1 - 7.6e-07 29.3 0.9 1.2e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 EGG23903.1 - 0.0069 16.4 0.1 0.02 14.9 0.1 1.8 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Ependymin PF00811.18 EGG23904.1 - 0.0001 22.5 0.1 0.0001 22.5 0.1 2.8 3 0 0 3 3 3 1 Ependymin Spc7 PF08317.11 EGG23904.1 - 0.0039 16.1 25.2 0.0039 16.1 25.2 7.4 3 2 5 8 8 8 2 Spc7 kinetochore protein ATG16 PF08614.11 EGG23904.1 - 0.0045 17.3 9.9 0.0045 17.3 9.9 8.6 2 1 5 7 7 7 3 Autophagy protein 16 (ATG16) DUF3618 PF12277.8 EGG23904.1 - 0.34 11.2 4.1 7.5 6.9 2.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Androgen_recep PF02166.16 EGG23904.1 - 4.3 6.1 8.4 13 4.5 8.4 1.8 1 0 0 1 1 1 0 Androgen receptor Glyco_hydro_35 PF01301.19 EGG23905.1 - 9.5e-33 114.2 1.4 1.5e-32 113.5 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 FNIP PF05725.12 EGG23906.1 - 9.1e-18 64.2 26.5 0.00057 20.0 0.6 9.7 4 3 7 11 11 11 9 FNIP Repeat Shisa PF13908.6 EGG23909.1 - 0.0021 18.3 5.3 0.0021 18.3 5.3 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator TFIIA PF03153.13 EGG23909.1 - 0.58 10.1 25.5 0.67 9.9 25.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FNIP PF05725.12 EGG23910.1 - 6.7e-22 77.4 19.0 0.0022 18.1 0.0 9.8 7 2 2 10 10 10 7 FNIP Repeat F-box-like PF12937.7 EGG23910.1 - 0.12 12.3 0.2 0.56 10.2 0.0 2.3 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.7 EGG23910.1 - 3.4 8.2 13.0 0.87 10.1 0.7 4.7 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) SNF2_N PF00176.23 EGG23911.1 - 2.8e-23 82.2 0.0 2.8e-23 82.2 0.0 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGG23911.1 - 3e-12 46.9 0.1 1.8e-11 44.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Flavi_DEAD PF07652.14 EGG23911.1 - 0.039 13.9 0.2 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 Flavivirus DEAD domain TMEM52 PF14979.6 EGG23911.1 - 1.1 9.2 4.3 4.4 7.2 0.3 2.6 2 0 0 2 2 2 0 Transmembrane 52 U-box PF04564.15 EGG23912.1 - 4e-13 49.4 0.2 9.3e-13 48.2 0.2 1.6 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.7 EGG23912.1 - 1.1e-07 32.0 0.2 2.7e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 EGG23912.1 - 1.2e-07 31.4 0.2 3.6e-07 29.9 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 EGG23912.1 - 1.9e-07 30.8 0.1 3.8e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG23912.1 - 6.5e-07 29.6 0.3 1.3e-06 28.6 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGG23912.1 - 1.6e-06 28.0 0.1 3.7e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGG23912.1 - 6.3e-06 26.0 0.1 1.5e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG23912.1 - 6.6e-05 22.7 0.2 0.00014 21.6 0.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGG23912.1 - 0.0011 18.9 0.1 0.0021 17.9 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Acetyltransf_1 PF00583.25 EGG23912.1 - 0.0014 18.8 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-C3HC4_4 PF15227.6 EGG23912.1 - 0.0033 17.6 0.1 0.0072 16.5 0.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 EGG23912.1 - 0.0034 16.8 1.1 0.005 16.2 1.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 EGG23912.1 - 0.0054 16.6 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGG23912.1 - 0.025 14.6 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger GlcNAc PF11397.8 EGG23912.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) Acetyltransf_10 PF13673.7 EGG23912.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HI0933_like PF03486.14 EGG23912.1 - 0.14 10.8 3.0 0.24 10.1 3.0 1.2 1 0 0 1 1 1 0 HI0933-like protein COesterase PF00135.28 EGG23913.1 - 1.8e-111 373.5 0.0 8.6e-111 371.3 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG23913.1 - 1e-05 25.5 0.1 2.8e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ribosomal_L4 PF00573.22 EGG23914.1 - 3e-53 180.4 0.6 4.2e-53 179.9 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family L51_S25_CI-B8 PF05047.16 EGG23915.1 - 2.4e-07 30.6 0.1 6.6e-07 29.1 0.1 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RasGAP PF00616.19 EGG23916.1 - 3.5e-31 108.6 5.7 6.2e-21 75.1 0.0 3.4 2 2 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase BAR_3 PF16746.5 EGG23916.1 - 2.9e-10 40.3 15.6 2.9e-10 40.3 15.6 2.7 3 0 0 3 3 3 1 BAR domain of APPL family BAR PF03114.18 EGG23916.1 - 8.9e-07 28.8 5.5 8.9e-07 28.8 5.5 2.2 1 1 2 3 3 3 1 BAR domain DUF5347 PF17282.2 EGG23916.1 - 0.042 14.2 0.3 0.14 12.5 0.3 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5347) Eisosome1 PF12757.7 EGG23916.1 - 0.55 10.5 7.4 0.25 11.6 4.7 1.8 2 0 0 2 2 2 0 Eisosome protein 1 GlutR_dimer PF00745.20 EGG23916.1 - 0.64 10.5 5.9 4.7 7.7 0.2 3.3 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain ISG65-75 PF11727.8 EGG23916.1 - 0.67 9.1 5.2 0.11 11.7 0.6 1.9 2 0 0 2 2 2 0 Invariant surface glycoprotein CorA PF01544.18 EGG23917.1 - 1.2e-06 28.0 2.6 1.2e-06 28.0 2.6 2.3 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Peroxin-13_N PF04088.13 EGG23917.1 - 0.032 14.5 1.2 0.032 14.5 1.2 2.4 3 0 0 3 3 3 0 Peroxin 13, N-terminal region SMAP PF15477.6 EGG23917.1 - 0.99 10.4 11.2 0.12 13.3 4.0 2.5 2 0 0 2 2 2 0 Small acidic protein family Peptidase_Prp PF04327.12 EGG23917.1 - 1.6 9.0 4.2 1.8 8.8 0.3 2.6 2 0 0 2 2 2 0 Cysteine protease Prp Menin PF05053.13 EGG23917.1 - 2.4 6.4 7.6 3.8 5.8 7.6 1.2 1 0 0 1 1 1 0 Menin ATP-grasp_2 PF08442.10 EGG23918.1 - 2.4e-74 249.3 1.8 4.1e-74 248.5 1.8 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EGG23918.1 - 1.7e-27 96.1 3.6 2.9e-27 95.4 3.6 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EGG23918.1 - 6.2e-11 42.2 0.4 1e-10 41.5 0.4 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EGG23918.1 - 0.00039 20.3 0.2 0.0011 18.7 0.2 1.9 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DAO_C PF16901.5 EGG23918.1 - 0.052 13.4 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 C-terminal domain of alpha-glycerophosphate oxidase Suv3_C_1 PF18147.1 EGG23919.1 - 1.2e-10 41.1 0.0 2.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 EGG23919.1 - 1.3e-10 41.5 0.0 6.2e-10 39.4 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.8 EGG23919.1 - 1.2e-08 34.8 0.1 3e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal DUF3430 PF11912.8 EGG23920.1 - 1.2e-13 51.6 7.9 1.2e-13 51.6 7.9 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3430) API5 PF05918.11 EGG23921.1 - 0.054 12.3 0.0 0.056 12.2 0.0 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Actin PF00022.19 EGG23922.1 - 5.1e-147 489.7 0.0 1.6e-146 488.1 0.0 1.6 1 1 0 1 1 1 1 Actin YDG PF18657.1 EGG23925.1 - 0.087 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 YDG domain Glyco_hydro_47 PF01532.20 EGG23926.1 - 4.8e-111 371.9 0.0 8.3e-111 371.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ODV-E18 PF10717.9 EGG23926.1 - 0.23 11.3 0.3 0.51 10.3 0.3 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 RRM_1 PF00076.22 EGG23927.1 - 4.9e-24 83.9 0.5 5.3e-13 48.6 0.2 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG23927.1 - 0.00016 21.6 0.1 0.00041 20.3 0.1 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGG23927.1 - 0.00058 19.9 0.0 0.0031 17.5 0.0 2.3 1 0 0 1 1 1 1 RNA binding motif DUF1664 PF07889.12 EGG23927.1 - 0.029 14.4 0.4 0.029 14.4 0.4 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) RRM_occluded PF16842.5 EGG23927.1 - 0.049 13.5 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif Insulin_TMD PF17870.1 EGG23928.1 - 0.0016 18.5 0.3 0.0041 17.2 0.3 1.7 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DUF3834 PF12916.7 EGG23928.1 - 0.087 12.1 0.4 0.7 9.1 0.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3834) FNIP PF05725.12 EGG23929.1 - 1.4e-137 447.7 7.5 7e-15 54.9 0.0 10.1 4 2 2 10 10 10 10 FNIP Repeat Phage_min_tail PF05939.13 EGG23929.1 - 2.8e-07 30.9 1.7 7.5 7.0 0.0 7.9 4 3 4 8 8 8 1 Phage minor tail protein ChlI PF13541.6 EGG23929.1 - 5.3e-06 26.3 0.2 2.4 8.0 0.1 5.7 3 2 3 6 6 6 2 Subunit ChlI of Mg-chelatase zf-RING_2 PF13639.6 EGG23930.1 - 1.3e-08 35.1 6.8 2.6e-08 34.1 6.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGG23930.1 - 2.7e-06 27.0 5.9 2.7e-06 27.0 5.9 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EGG23930.1 - 1.9e-05 24.9 3.0 4.9e-05 23.5 3.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGG23930.1 - 2.9e-05 23.9 5.4 5.9e-05 22.9 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG23930.1 - 8.1e-05 22.4 6.7 0.00019 21.2 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG23930.1 - 0.00024 21.0 3.5 0.00047 20.0 3.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGG23930.1 - 0.0005 20.1 1.3 0.0013 18.8 1.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGG23930.1 - 0.00084 18.9 2.3 0.0019 17.8 2.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EGG23930.1 - 0.0032 17.4 4.4 0.0085 16.1 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 EGG23930.1 - 0.018 15.2 2.5 0.057 13.6 2.5 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 EGG23930.1 - 0.046 13.6 4.9 0.091 12.6 4.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGG23930.1 - 0.15 11.9 3.9 0.28 11.1 3.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EGG23930.1 - 0.17 12.0 4.9 0.36 11.0 4.9 1.5 1 0 0 1 1 1 0 RING-variant domain Syndecan PF01034.20 EGG23930.1 - 0.56 10.2 3.2 2.7 8.0 3.2 2.1 1 0 0 1 1 1 0 Syndecan domain SASRP1 PF15160.6 EGG23930.1 - 2.9 7.5 6.4 6.3 6.4 6.4 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 Macoilin PF09726.9 EGG23930.1 - 8.6 4.8 6.5 11 4.5 6.5 1.1 1 0 0 1 1 1 0 Macoilin family FF PF01846.19 EGG23931.1 - 1.1e-36 124.7 36.2 3.1e-11 43.2 0.4 6.8 9 0 0 9 9 9 5 FF domain WW PF00397.26 EGG23931.1 - 3.7e-18 65.3 15.0 2.2e-10 40.4 1.4 3.3 3 0 0 3 3 3 2 WW domain PDEase_I PF00233.19 EGG23932.1 - 1.1e-78 264.3 10.1 1.1e-78 264.3 10.1 2.8 4 0 0 4 4 4 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 EGG23932.1 - 1e-27 96.5 0.7 2.5e-27 95.2 0.7 1.7 1 0 0 1 1 1 1 Response regulator receiver domain FliG_N PF14842.6 EGG23932.1 - 0.3 11.7 4.6 2.9 8.5 1.3 3.4 4 0 0 4 4 4 0 FliG N-terminal domain DUF4446 PF14584.6 EGG23932.1 - 2.5 8.1 7.2 7.1 6.6 5.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) zf-UBR PF02207.20 EGG23933.1 - 3.4e-17 62.4 12.1 3.4e-17 62.4 12.1 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ELL PF10390.9 EGG23933.1 - 0.0023 17.5 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL WH2 PF02205.20 EGG23934.1 - 3.2e-09 36.3 2.9 0.0014 18.4 0.1 3.9 4 0 0 4 4 4 3 WH2 motif EIF_2_alpha PF07541.12 EGG23935.1 - 1.1e-34 119.0 0.0 2.1e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EGG23935.1 - 9.8e-11 41.9 2.1 9.8e-11 41.9 2.1 2.1 3 0 0 3 3 3 1 S1 RNA binding domain AKNA PF12443.8 EGG23935.1 - 0.071 13.8 2.0 0.79 10.4 0.0 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor TFIIF_alpha PF05793.12 EGG23936.1 - 0.71 8.4 3.2 0.99 7.9 3.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DSPc PF00782.20 EGG23937.1 - 1.9e-32 111.9 0.0 1.9e-32 111.9 0.0 2.9 3 1 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGG23937.1 - 5.8e-05 22.8 0.1 5.8e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGG23937.1 - 0.011 15.8 3.3 0.012 15.8 0.0 2.4 3 0 0 3 3 3 0 Inositol hexakisphosphate DUF4529 PF15032.6 EGG23937.1 - 0.012 14.7 0.0 0.039 13.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) CDKN3 PF05706.12 EGG23937.1 - 0.054 13.2 0.8 0.077 12.7 0.1 1.6 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Menin PF05053.13 EGG23937.1 - 9.9 4.4 13.8 0.18 10.1 5.2 2.0 2 0 0 2 2 2 0 Menin ATP-synt_F PF01990.17 EGG23938.1 - 3.6e-27 94.5 0.2 5e-27 94.1 0.2 1.2 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit UFD1 PF03152.14 EGG23940.1 - 1e-72 243.2 0.1 1.4e-72 242.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 SR-25 PF10500.9 EGG23940.1 - 0.1 12.2 5.6 0.15 11.6 5.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NTP_transferase PF00483.23 EGG23941.1 - 9.7e-27 94.1 0.0 1.4e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EGG23941.1 - 3.5e-07 29.7 4.4 9.5e-06 25.1 1.2 3.1 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EGG23941.1 - 2.5e-06 27.9 0.0 3.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EGG23941.1 - 0.063 13.0 0.4 0.3 10.9 0.1 2.3 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EGG23941.1 - 0.077 11.1 0.1 0.15 10.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Pet127 PF08634.10 EGG23943.1 - 1.1e-81 274.3 2.9 3.1e-81 272.8 2.9 1.8 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Syja_N PF02383.18 EGG23944.1 - 7.4e-40 137.2 29.6 1.6e-39 136.1 24.5 3.1 2 1 0 2 2 2 1 SacI homology domain FYVE PF01363.21 EGG23944.1 - 0.00052 20.1 3.9 0.0017 18.5 3.9 1.9 1 0 0 1 1 1 1 FYVE zinc finger DUF4296 PF14129.6 EGG23944.1 - 0.029 15.0 1.3 1.7 9.3 0.5 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) IBR PF01485.21 EGG23944.1 - 0.16 12.2 4.7 0.51 10.6 4.7 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 EGG23944.1 - 0.19 11.9 3.0 0.54 10.5 3.0 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger Amidase PF01425.21 EGG23945.1 - 5e-66 223.5 1.7 5.9e-65 220.0 1.7 2.0 1 1 0 1 1 1 1 Amidase DUF148 PF02520.17 EGG23945.1 - 0.022 14.8 0.7 0.061 13.4 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function DUF148 PepX_N PF09168.10 EGG23945.1 - 0.11 12.9 0.1 4.1 7.8 0.1 2.3 2 0 0 2 2 2 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Intein_splicing PF14890.6 EGG23947.1 - 0.018 15.0 0.0 0.42 10.6 0.0 2.8 2 1 1 3 3 3 0 Intein splicing domain DUF835 PF05763.12 EGG23948.1 - 0.03 14.1 0.4 0.088 12.5 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF835) PAXX PF15384.6 EGG23948.1 - 8.3 6.0 12.2 5.9 6.5 4.2 2.7 2 0 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 BB_PF PF18063.1 EGG23949.1 - 1.2e-28 100.1 3.7 1.4e-27 96.6 1.5 2.0 1 1 1 2 2 2 2 Beta barrel Pore-forming domain MMTV_SAg PF01054.17 EGG23949.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen NAGLU PF05089.12 EGG23951.1 - 0.087 11.8 0.5 0.51 9.2 0.1 2.2 2 1 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain SSP160 PF06933.11 EGG23951.1 - 0.15 10.2 0.5 0.21 9.8 0.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ribosomal_L24e PF01246.20 EGG23952.1 - 0.078 13.2 0.1 0.085 13.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L24e Pyr_redox_2 PF07992.14 EGG23953.1 - 2.6e-68 230.4 11.7 3.4e-68 230.0 11.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGG23953.1 - 1.3e-40 138.0 0.2 3.4e-40 136.7 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGG23953.1 - 5.8e-24 84.5 8.5 2.4e-20 72.9 1.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG23953.1 - 4.6e-10 39.2 11.6 1.6e-07 30.9 1.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGG23953.1 - 5.2e-09 35.9 1.3 5.2e-09 35.9 1.3 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG23953.1 - 5.1e-07 28.7 12.2 2.2e-05 23.3 0.6 3.5 3 1 1 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 EGG23953.1 - 5.1e-06 25.9 7.0 0.0072 15.6 0.2 3.4 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EGG23953.1 - 8.4e-06 25.1 13.8 2.9e-05 23.3 7.5 3.0 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGG23953.1 - 2.3e-05 23.7 3.6 2.3e-05 23.7 3.6 3.7 2 1 2 4 4 4 1 FAD binding domain NAD_binding_8 PF13450.6 EGG23953.1 - 0.00014 22.0 1.4 0.00014 22.0 1.4 3.2 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EGG23953.1 - 0.0065 16.4 0.2 0.0065 16.4 0.2 2.6 4 0 0 4 4 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 EGG23953.1 - 0.011 15.0 4.7 0.013 14.6 0.2 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EGG23953.1 - 0.012 14.9 2.7 0.012 14.9 2.7 2.8 2 1 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EGG23953.1 - 0.017 14.2 5.8 0.034 13.2 0.1 2.8 2 1 1 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 EGG23953.1 - 0.026 13.8 10.2 0.013 14.8 5.1 2.9 1 1 1 2 2 2 0 Thi4 family DAO PF01266.24 EGG23953.1 - 0.029 14.0 20.1 0.19 11.2 0.4 4.0 2 1 2 4 4 4 0 FAD dependent oxidoreductase XdhC_C PF13478.6 EGG23953.1 - 0.035 14.6 0.3 4.9 7.7 0.0 2.7 3 0 0 3 3 2 0 XdhC Rossmann domain Amino_oxidase PF01593.24 EGG23953.1 - 0.13 11.5 5.0 4.9 6.3 0.1 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 EGG23953.1 - 2.4 8.7 5.7 15 6.1 0.7 3.0 2 2 0 2 2 2 0 Putative NAD(P)-binding KH_6 PF15985.5 EGG23954.1 - 1.9e-13 50.5 0.0 5.2e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 EGG23954.1 - 3.2e-11 42.8 0.3 5.6e-11 42.0 0.3 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region DHHC PF01529.20 EGG23955.1 - 1e-34 119.5 1.8 1e-34 119.5 1.8 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF5065 PF16723.5 EGG23955.1 - 0.14 12.2 3.8 0.78 9.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) DUF4834 PF16118.5 EGG23955.1 - 0.17 12.8 14.9 1.7e+02 3.2 0.0 4.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Pex14_N PF04695.13 EGG23955.1 - 3.2 8.4 13.5 0.24 12.1 0.6 3.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UCH PF00443.29 EGG23956.1 - 1.6e-40 139.2 5.6 1.6e-40 139.2 5.6 2.7 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG23956.1 - 8.6e-20 71.6 3.6 8.6e-20 71.6 3.6 4.6 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase Utp11 PF03998.13 EGG23957.1 - 4.1e-20 72.7 5.3 5e-20 72.5 5.3 1.0 1 0 0 1 1 1 1 Utp11 protein Pkinase PF00069.25 EGG23958.1 - 1.7e-75 253.8 0.4 4.5e-75 252.4 0.4 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23958.1 - 6.7e-36 123.9 0.0 1.2e-35 123.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG23958.1 - 6e-07 29.1 0.0 1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGG23958.1 - 2.9e-06 26.8 0.3 5.2e-06 26.0 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG23958.1 - 0.017 15.1 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ADP_PFK_GK PF04587.15 EGG23959.1 - 2.7e-133 444.6 0.1 3.9e-133 444.1 0.1 1.2 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region Nitro_FeMo-Co PF02579.17 EGG23959.1 - 0.0019 18.5 0.0 0.27 11.6 0.0 2.4 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor Palm_thioest PF02089.15 EGG23959.1 - 0.0052 16.6 0.0 0.034 14.0 0.0 2.1 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Esterase PF00756.20 EGG23959.1 - 0.0088 15.7 0.1 0.027 14.1 0.1 1.8 2 0 0 2 2 2 1 Putative esterase Abhydrolase_6 PF12697.7 EGG23959.1 - 0.011 16.3 0.1 0.026 15.1 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family NUDIX PF00293.28 EGG23960.1 - 7.7e-08 32.4 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_1 PF00561.20 EGG23960.1 - 1.2e-06 28.3 0.2 1.9e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG23960.1 - 0.0023 18.6 0.1 0.0038 17.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Mab-21 PF03281.14 EGG23960.1 - 0.19 11.0 0.1 0.31 10.3 0.1 1.2 1 0 0 1 1 1 0 Mab-21 protein Pkinase PF00069.25 EGG23961.1 - 1.1e-39 136.4 0.0 1.7e-32 112.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23961.1 - 2.6e-28 99.0 0.0 6.4e-28 97.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_1 PF00583.25 EGG23961.1 - 1.4e-05 25.3 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pkinase_fungal PF17667.1 EGG23961.1 - 0.00061 18.7 0.6 0.0015 17.4 0.6 1.6 1 1 0 1 1 1 1 Fungal protein kinase Acetyltransf_7 PF13508.7 EGG23961.1 - 0.00067 20.0 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG23961.1 - 0.0024 17.8 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGG23961.1 - 0.0038 17.3 0.0 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Kinase-like PF14531.6 EGG23961.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGG23961.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGG23962.1 - 4.1e-39 134.5 0.1 3.9e-33 115.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG23962.1 - 1.8e-27 96.3 0.0 3.7e-27 95.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG23962.1 - 1.5e-05 24.0 0.0 2.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Acetyltransf_1 PF00583.25 EGG23962.1 - 5.8e-05 23.3 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG23962.1 - 0.0018 18.7 0.0 0.004 17.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG23962.1 - 0.0037 17.2 0.0 0.0084 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGG23962.1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Kinase-like PF14531.6 EGG23962.1 - 0.054 12.8 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FAM220 PF15487.6 EGG23962.1 - 0.092 12.4 2.8 0.13 11.9 2.1 1.6 1 1 0 1 1 1 0 FAM220 family Ceramidase PF05875.12 EGG23963.1 - 4.3e-59 200.1 9.5 5e-59 199.9 9.5 1.1 1 0 0 1 1 1 1 Ceramidase TauE PF01925.19 EGG23963.1 - 0.0021 17.7 1.6 0.0051 16.5 1.6 1.6 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Polysacc_synt_C PF14667.6 EGG23963.1 - 0.16 12.0 6.0 0.33 11.0 2.0 2.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain ETRAMP PF09716.10 EGG23963.1 - 3 8.0 5.2 16 5.6 0.0 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF1479 PF07350.12 EGG23964.1 - 3.1e-06 26.2 0.4 0.0018 17.1 0.1 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 EGG23964.1 - 0.0057 16.9 0.0 0.022 15.0 0.0 1.8 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Oxysterol_BP PF01237.18 EGG23965.1 - 5.6e-65 219.6 6.9 4.1e-62 210.2 6.9 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein GATA PF00320.27 EGG23966.1 - 2.2e-15 55.9 5.1 2.2e-15 55.9 5.1 2.0 2 0 0 2 2 2 1 GATA zinc finger Fimbrial_CS1 PF04449.12 EGG23966.1 - 0.016 15.4 1.0 0.034 14.3 1.0 1.5 1 0 0 1 1 1 0 CS1 type fimbrial major subunit Glyco_hydro_9 PF00759.19 EGG23967.1 - 7.1e-126 420.9 12.5 8.8e-126 420.6 12.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_127 PF07944.12 EGG23967.1 - 0.017 13.7 0.1 0.041 12.4 0.0 1.6 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 SAP130_C PF16014.5 EGG23967.1 - 6.2 5.8 6.9 9.7 5.2 6.9 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus NEMO PF11577.8 EGG23968.1 - 0.0046 16.9 7.9 0.0046 16.9 7.9 2.4 2 1 0 2 2 2 1 NF-kappa-B essential modulator NEMO Prefoldin_2 PF01920.20 EGG23968.1 - 0.0081 16.1 13.5 0.011 15.7 13.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit Cep57_MT_bd PF06657.13 EGG23968.1 - 0.31 11.5 11.6 3.2 8.3 4.1 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DIT1_PvcA PF05141.12 EGG23968.1 - 0.58 9.6 8.8 0.62 9.5 8.8 1.0 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Vir_act_alpha_C PF10400.9 EGG23968.1 - 2.5 8.8 7.7 11 6.8 0.1 2.3 2 0 0 2 2 2 0 Virulence activator alpha C-term FliD_N PF02465.18 EGG23968.1 - 6.6 7.5 9.8 1.9 9.2 2.4 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DP PF08781.10 EGG23968.1 - 6.8 6.6 16.2 9.2 6.2 7.9 2.1 2 0 0 2 2 2 0 Transcription factor DP DUF4298 PF14131.6 EGG23968.1 - 8.9 6.4 15.8 1.8 8.6 8.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) Ank_2 PF12796.7 EGG23969.1 - 1.5e-06 28.7 0.4 0.2 12.3 0.2 5.1 6 0 0 6 6 6 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG23969.1 - 3.5e-05 24.0 0.2 4.2 7.8 0.0 5.5 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23969.1 - 9e-05 22.6 0.1 27 5.8 0.0 6.5 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 EGG23969.1 - 0.0092 16.5 0.0 67 4.2 0.0 5.1 4 1 1 5 5 5 0 Ankyrin repeats (many copies) MAT1-1-2 PF17043.5 EGG23969.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function PhyH PF05721.13 EGG23970.1 - 8.7e-07 29.4 1.5 2.4e-05 24.7 0.0 3.0 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EGG23970.1 - 0.011 16.1 0.6 0.085 13.3 0.0 2.6 2 1 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase PI3_PI4_kinase PF00454.27 EGG23971.1 - 3.4e-33 115.5 0.7 3.4e-33 115.5 0.7 4.4 4 2 0 4 4 4 1 Phosphatidylinositol 3- and 4-kinase Ank_2 PF12796.7 EGG23972.1 - 1.2e-54 182.9 32.7 2.7e-11 43.9 0.1 7.3 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG23972.1 - 1.5e-42 143.4 21.1 3.8e-08 33.7 0.2 9.5 7 3 2 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG23972.1 - 1.4e-30 105.0 26.8 3.3e-05 24.1 0.1 12.5 5 2 9 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23972.1 - 9.6e-28 93.2 13.8 0.006 17.0 0.0 14.0 15 1 1 16 16 16 5 Ankyrin repeat DUF5049 PF16468.5 EGG23972.1 - 2.5e-12 46.5 9.1 1.8 8.5 0.0 9.9 5 4 6 11 11 11 4 Domain of unknown function (DUF5049) Ank PF00023.30 EGG23972.1 - 6.2e-11 42.2 8.6 0.83 10.2 0.0 10.8 7 3 4 11 11 11 3 Ankyrin repeat Sushi_2 PF09014.10 EGG23972.1 - 0.23 11.4 9.0 1.3 8.9 0.1 5.0 3 2 1 5 5 5 0 Beta-2-glycoprotein-1 fifth domain ACTH_assoc PF16102.5 EGG23972.1 - 0.24 12.2 0.8 0.48 11.3 0.8 1.4 1 0 0 1 1 1 0 ACTH-associated domain CN_hydrolase PF00795.22 EGG23973.1 - 7.4e-31 107.4 0.0 9.1e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF1084 PF06454.11 EGG23974.1 - 4e-06 26.4 25.6 1.7e-05 24.4 25.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Aminotran_1_2 PF00155.21 EGG23975.1 - 2.2e-75 254.1 0.0 3.1e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGG23975.1 - 3e-07 29.3 0.4 5.9e-07 28.4 0.1 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGG23975.1 - 3.9e-06 26.1 0.1 1.1e-05 24.6 0.2 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Preseq_ALAS PF09029.10 EGG23975.1 - 0.013 16.0 7.4 0.037 14.5 6.9 2.1 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence SMYLE_N PF18615.1 EGG23975.1 - 0.056 13.0 5.8 0.098 12.2 5.8 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain COG5 PF10392.9 EGG23976.1 - 0.049 13.8 0.8 0.19 11.9 0.8 2.0 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Menin PF05053.13 EGG23976.1 - 0.084 11.2 1.4 0.085 11.2 1.4 1.1 1 0 0 1 1 1 0 Menin AAA_11 PF13086.6 EGG23977.1 - 1.8e-62 211.5 0.2 1.8e-62 211.5 0.2 3.7 2 1 1 3 3 2 1 AAA domain AAA_12 PF13087.6 EGG23977.1 - 1.9e-55 187.6 0.1 1.9e-55 187.6 0.1 3.1 3 1 0 3 3 2 1 AAA domain R3H PF01424.22 EGG23977.1 - 7.5e-17 61.1 0.1 3.6e-16 58.9 0.0 2.3 2 0 0 2 2 2 1 R3H domain AAA_30 PF13604.6 EGG23977.1 - 1e-14 54.7 0.1 1.6e-13 50.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGG23977.1 - 1.9e-10 41.3 0.0 1e-09 38.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain zf-AN1 PF01428.16 EGG23977.1 - 2.9e-08 33.7 4.9 5e-08 33.0 4.9 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Viral_helicase1 PF01443.18 EGG23977.1 - 4.9e-07 29.7 2.5 0.37 10.5 0.0 4.1 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 EGG23977.1 - 0.00065 19.1 0.0 0.00065 19.1 0.0 2.9 3 1 0 4 4 3 1 KaiC AAA_16 PF13191.6 EGG23977.1 - 0.0048 17.3 1.8 0.0069 16.8 0.1 2.2 2 1 0 2 2 1 1 AAA ATPase domain MeaB PF03308.16 EGG23977.1 - 0.0054 15.8 0.0 0.016 14.2 0.0 1.7 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Flavi_DEAD PF07652.14 EGG23977.1 - 0.0079 16.2 0.0 0.036 14.0 0.0 2.1 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_22 PF13401.6 EGG23977.1 - 0.011 16.0 4.3 0.032 14.5 0.7 3.3 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 EGG23977.1 - 0.011 15.2 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Helicase_RecD PF05127.14 EGG23977.1 - 0.031 14.1 8.2 0.1 12.4 0.0 4.4 4 1 1 5 5 5 0 Helicase UvrD_C_2 PF13538.6 EGG23977.1 - 0.034 14.0 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_25 PF13481.6 EGG23977.1 - 0.036 13.7 0.5 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGG23977.1 - 0.061 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.23 EGG23977.1 - 0.1 12.7 0.6 0.3 11.1 0.6 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EGG23977.1 - 0.11 12.2 0.0 0.11 12.2 0.0 4.1 3 2 0 3 3 2 0 AAA domain BSP_II PF05432.11 EGG23977.1 - 0.41 10.3 28.1 0.7 9.5 14.3 3.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) zf-CGNR PF11706.8 EGG23977.1 - 0.53 10.2 2.5 1.5 8.7 2.2 1.9 2 0 0 2 2 2 0 CGNR zinc finger AAA PF00004.29 EGG23977.1 - 1.2 9.5 10.0 0.078 13.4 1.4 3.5 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF2052 PF09747.9 EGG23977.1 - 9.6 6.3 35.2 17 5.5 18.0 2.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) UBX PF00789.20 EGG23978.1 - 1.4e-11 44.5 0.0 3.2e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 EGG23978.1 - 1.1e-05 25.5 0.3 0.00015 21.9 0.1 2.7 3 0 0 3 3 3 1 Thioredoxin-like LapA_dom PF06305.11 EGG23978.1 - 0.0063 16.3 0.0 0.0063 16.3 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain eIF3_subunit PF08597.10 EGG23978.1 - 0.081 12.8 9.3 0.14 12.0 9.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit ET PF01684.16 EGG23978.1 - 0.1 12.9 1.1 0.23 11.8 1.1 1.5 1 0 0 1 1 1 0 ET module DUF4574 PF15141.6 EGG23978.1 - 0.18 11.8 0.0 0.18 11.8 0.0 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Casc1_N PF15927.5 EGG23978.1 - 3.4 7.3 17.1 7.2 6.2 17.1 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Peptidase_M50B PF13398.6 EGG23979.1 - 0.032 13.9 5.2 0.046 13.3 5.2 1.1 1 0 0 1 1 1 0 Peptidase M50B-like DUF4834 PF16118.5 EGG23979.1 - 1.1 10.2 10.6 4 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Mad3_BUB1_I PF08311.12 EGG23983.1 - 0.08 12.9 4.9 0.081 12.9 0.1 3.5 4 1 1 5 5 5 0 Mad3/BUB1 homology region 1 Acetyltransf_14 PF03421.16 EGG23983.1 - 0.32 11.1 5.3 0.43 10.6 0.0 3.6 3 1 2 5 5 5 0 YopJ Serine/Threonine acetyltransferase EF-hand_2 PF09068.11 EGG23983.1 - 0.92 9.7 5.5 0.44 10.7 1.1 2.8 2 1 0 2 2 2 0 EF hand GMC_oxred_N PF00732.19 EGG23986.1 - 4e-15 56.0 0.0 5.4e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EGG23986.1 - 0.0098 16.1 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGG23986.1 - 0.01 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EGG23986.1 - 0.06 12.4 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 EGG23986.1 - 0.14 11.7 0.0 0.36 10.4 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG23986.1 - 0.16 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FSAP_sig_propep PF03032.15 EGG23986.1 - 0.36 10.9 1.6 0.47 10.5 0.1 1.9 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide GMC_oxred_C PF05199.13 EGG23987.1 - 0.012 16.1 0.0 0.018 15.6 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase PPI_Ypi1 PF07491.11 EGG23988.1 - 0.41 10.5 2.7 0.59 10.0 2.7 1.5 1 1 0 1 1 1 0 Protein phosphatase inhibitor Epimerase PF01370.21 EGG23990.1 - 6.9e-22 78.1 0.2 8.8e-21 74.5 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGG23990.1 - 8e-21 74.3 3.5 1.6e-17 63.5 0.3 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGG23990.1 - 1.4e-13 50.7 0.1 3.1e-07 29.8 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EGG23990.1 - 5.1e-10 39.6 0.0 8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGG23990.1 - 6e-09 35.8 0.7 3e-06 26.9 0.6 3.0 3 1 0 3 3 3 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGG23990.1 - 1.4e-07 30.9 0.0 6.2e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGG23990.1 - 4.3e-06 26.1 0.0 0.00019 20.7 0.1 2.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EGG23990.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EGG23990.1 - 0.00035 20.8 0.0 0.00067 19.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EGG23990.1 - 0.0015 18.4 0.2 0.014 15.3 0.2 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EGG23990.1 - 0.011 15.3 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Zip PF02535.22 EGG23990.1 - 0.034 13.4 0.6 0.05 12.8 0.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter LMBR1 PF04791.16 EGG23990.1 - 0.04 12.8 1.5 0.067 12.1 1.4 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Macoilin PF09726.9 EGG23990.1 - 0.076 11.6 4.0 0.099 11.2 4.0 1.1 1 0 0 1 1 1 0 Macoilin family Semialdhyde_dh PF01118.24 EGG23990.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Presenilin PF01080.17 EGG23990.1 - 4.6 5.9 6.1 7.7 5.2 6.1 1.3 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 EGG23991.1 - 9.2e-17 61.4 0.2 0.00057 20.4 0.0 6.1 5 2 2 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG23991.1 - 2.6e-16 59.8 0.6 0.017 15.7 0.0 7.4 7 1 1 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG23991.1 - 2.5e-08 33.5 2.6 5.8 7.8 0.0 8.3 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 EGG23991.1 - 1.1e-06 28.8 0.1 20 5.6 0.0 7.0 8 1 1 9 9 9 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EGG23991.1 - 0.0063 16.5 14.9 0.36 10.8 0.0 6.5 5 2 0 6 6 6 1 Domain of unknown function (DUF3447) DUF1707 PF08044.11 EGG23991.1 - 0.034 14.2 1.8 0.34 11.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) Ank PF00023.30 EGG23991.1 - 0.22 12.0 0.5 27 5.4 0.1 4.3 3 1 0 3 3 3 0 Ankyrin repeat Vinculin PF01044.19 EGG23992.1 - 2.5e-17 62.5 13.4 2.5e-17 62.5 13.4 8.4 2 2 4 7 7 7 2 Vinculin family PSD2 PF07624.11 EGG23992.1 - 0.17 11.7 1.9 4 7.3 0.0 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1585) DPM3 PF08285.11 EGG23992.1 - 5.1 7.4 4.9 37 4.6 0.1 3.6 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FAT PF02259.23 EGG23993.1 - 1.4e-42 146.1 11.5 1e-41 143.4 11.5 2.4 1 1 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EGG23993.1 - 1.8e-06 28.0 0.2 5.1e-06 26.5 0.2 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Ank_3 PF13606.6 EGG23994.1 - 0.058 14.0 0.1 3.3 8.6 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 EGG23994.1 - 0.11 13.1 0.0 1.2 9.8 0.0 2.8 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Methyltransf_4 PF02390.17 EGG23995.1 - 1.6e-34 118.8 1.1 3.9e-33 114.4 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.6 EGG23995.1 - 0.00031 21.4 0.0 0.00093 19.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG23995.1 - 0.00043 20.1 2.7 0.00068 19.5 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Presenilin PF01080.17 EGG23995.1 - 0.0022 16.8 3.4 0.0026 16.6 3.4 1.1 1 0 0 1 1 1 1 Presenilin MTS PF05175.14 EGG23995.1 - 0.018 14.6 5.0 0.023 14.3 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase small domain Methyltransf_23 PF13489.6 EGG23995.1 - 0.039 13.8 0.0 0.14 12.0 0.0 2.0 1 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGG23995.1 - 0.057 14.1 0.2 0.58 10.9 0.0 2.6 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGG23995.1 - 0.07 13.9 0.0 0.07 13.9 0.0 3.2 2 1 0 2 2 2 0 Methyltransferase domain Glyco_hydro_19 PF00182.19 EGG23996.1 - 2.1e-43 148.9 9.4 1.6e-41 142.7 9.4 2.9 1 1 0 1 1 1 1 Chitinase class I OB_Dis3 PF17849.1 EGG23996.1 - 0.0011 18.9 0.4 3.9 7.6 0.0 3.6 3 0 0 3 3 3 1 Dis3-like cold-shock domain 2 (CSD2) Cu_bind_like PF02298.17 EGG23996.1 - 0.035 14.1 1.4 15 5.7 0.0 3.3 3 0 0 3 3 3 0 Plastocyanin-like domain DEC1 PF15859.5 EGG23996.1 - 1.2 9.2 2.8 93 3.2 0.2 3.2 3 0 0 3 3 3 0 Deleted in esophageal cancer 1 family Glyco_hydro_19 PF00182.19 EGG23998.1 - 1e-44 153.2 6.9 3.9e-36 125.1 1.5 2.7 1 1 1 2 2 2 2 Chitinase class I Glyco_hydro_19 PF00182.19 EGG23999.1 - 1.2e-43 149.7 4.4 8.6e-41 140.3 4.4 2.8 1 1 0 1 1 1 1 Chitinase class I mIF3 PF14877.6 EGG23999.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor VIT PF08487.10 EGG24000.1 - 1.4e-29 102.5 0.0 3.8e-29 101.1 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EGG24000.1 - 3.2e-26 92.1 0.0 9.6e-26 90.6 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EGG24000.1 - 7e-15 55.7 0.0 2.5e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGG24000.1 - 2.7e-11 44.0 0.0 1.2e-10 42.0 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 EGG24000.1 - 2.8e-07 30.4 0.0 7.4e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.9 EGG24000.1 - 0.046 13.8 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus zf-C4H2 PF10146.9 EGG24000.1 - 0.052 13.9 1.7 0.15 12.4 1.7 1.7 1 0 0 1 1 1 0 Zinc finger-containing protein Dehydrin PF00257.19 EGG24001.1 - 9 6.8 7.8 19 5.8 7.8 1.7 1 1 0 1 1 1 0 Dehydrin AAA-ATPase_like PF09820.9 EGG24002.1 - 8.1e-25 87.8 1.2 1.2e-24 87.2 1.2 1.2 1 0 0 1 1 1 1 Predicted AAA-ATPase BAR_3 PF16746.5 EGG24004.1 - 3.9e-12 46.4 11.0 7.3e-12 45.5 11.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family Takusan PF04822.13 EGG24004.1 - 0.017 15.0 2.1 0.12 12.3 2.1 2.4 1 1 0 1 1 1 0 Takusan DUF1635 PF07795.11 EGG24004.1 - 8.4 6.2 11.5 0.13 12.1 3.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1635) Pkinase PF00069.25 EGG24005.1 - 9.4e-80 267.8 0.0 1.2e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG24005.1 - 2.8e-39 134.9 0.0 4.1e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGG24005.1 - 3.9e-07 29.6 0.7 8.7e-07 28.5 0.7 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGG24005.1 - 0.004 16.5 1.4 0.088 12.1 1.6 2.6 1 1 1 2 2 2 1 Kinase-like DUF1367 PF07105.11 EGG24005.1 - 0.0052 16.5 0.7 0.08 12.6 0.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1367) APH PF01636.23 EGG24005.1 - 0.012 15.6 0.1 0.12 12.3 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EGG24005.1 - 0.017 14.7 0.4 0.1 12.1 0.4 2.1 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL IPK PF03770.16 EGG24006.1 - 1.2e-52 178.6 0.1 3e-52 177.4 0.0 1.7 2 0 0 2 2 2 1 Inositol polyphosphate kinase SWIRM PF04433.17 EGG24006.1 - 0.034 14.5 0.1 0.082 13.3 0.1 1.6 1 0 0 1 1 1 0 SWIRM domain TPR_19 PF14559.6 EGG24007.1 - 2.6e-08 34.2 0.0 0.012 16.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGG24007.1 - 1.9e-07 30.6 0.0 0.00041 20.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG24007.1 - 4.3e-06 26.3 0.0 0.00037 20.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGG24007.1 - 0.00089 19.3 0.1 0.85 10.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGG24007.1 - 0.0029 17.5 0.0 0.057 13.5 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG24007.1 - 0.0098 16.2 0.0 0.86 9.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGG24007.1 - 0.044 13.9 0.1 15 5.8 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG24007.1 - 0.051 14.4 0.0 19 6.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CENP-F_N PF10481.9 EGG24007.1 - 1.9 8.0 4.4 0.27 10.8 0.1 1.8 2 0 0 2 2 2 0 Cenp-F N-terminal domain tRNA-synt_1 PF00133.22 EGG24008.1 - 3.2e-177 590.4 0.8 4.3e-177 590.0 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGG24008.1 - 8.5e-23 81.0 0.8 1.8e-22 80.0 0.8 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGG24008.1 - 1.4e-19 70.1 2.6 7.1e-13 48.1 0.0 4.0 4 0 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGG24008.1 - 0.0014 18.2 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EGG24008.1 - 0.0022 17.4 0.0 1.3 8.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 EGG24008.1 - 0.062 13.2 8.5 0.14 12.0 8.5 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS BRF1 PF07741.13 EGG24009.1 - 0.011 16.1 1.7 0.011 16.1 1.7 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF5131 PF07505.11 EGG24009.1 - 0.03 13.8 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) PHINT_rpt PF14882.6 EGG24010.1 - 0.083 13.2 0.0 0.37 11.1 0.0 2.1 1 0 0 1 1 1 0 Phage-integrase repeat unit AbiJ_NTD4 PF18863.1 EGG24010.1 - 0.12 12.8 9.3 0.05 14.1 3.4 2.6 2 1 0 2 2 2 0 AbiJ N-terminal domain 4 tRNA-synt_1c PF00749.21 EGG24011.1 - 3.6e-105 351.3 0.0 5.1e-105 350.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Asparaginase PF00710.20 EGG24012.1 - 2e-64 216.6 0.0 3.8e-64 215.8 0.0 1.4 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EGG24012.1 - 8.8e-33 112.9 0.1 2.3e-32 111.6 0.1 1.7 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Senescence_reg PF04520.13 EGG24014.1 - 6.1 7.7 8.2 1.1 10.1 0.1 2.4 2 0 0 2 2 2 0 Senescence regulator Ank_2 PF12796.7 EGG24015.1 - 5.9e-112 366.5 38.3 6.2e-16 58.8 0.2 10.7 6 3 6 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24015.1 - 1.9e-85 280.2 27.6 7.6e-11 42.3 0.3 13.1 6 4 8 14 14 14 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24015.1 - 3.9e-83 272.4 32.8 3.9e-10 39.8 0.1 15.3 5 4 11 16 16 16 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24015.1 - 1.4e-72 231.0 29.7 5.4e-05 23.3 0.1 19.3 19 0 0 19 19 19 16 Ankyrin repeat Ank PF00023.30 EGG24015.1 - 1.7e-70 230.6 50.1 7.6e-07 29.3 0.1 18.4 18 0 0 18 18 18 16 Ankyrin repeat Maf PF02545.14 EGG24015.1 - 4.2e-44 150.3 0.0 6.9e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 Maf-like protein Peptidase_C1 PF00112.23 EGG24016.1 - 1.2e-71 241.3 7.8 2.2e-71 240.4 7.8 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG24016.1 - 1.7e-14 54.0 8.7 3.1e-14 53.2 6.0 2.3 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) DUF1002 PF06207.11 EGG24016.1 - 0.024 14.2 0.4 0.05 13.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Styelin PF17562.2 EGG24016.1 - 0.085 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Styelin Ependymin PF00811.18 EGG24016.1 - 3.4 7.9 5.7 1.6 9.0 0.2 3.0 3 0 0 3 3 3 0 Ependymin Ank_2 PF12796.7 EGG24017.1 - 0.04 14.5 0.4 26 5.5 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Na_H_Exchanger PF00999.21 EGG24018.1 - 2.8e-59 200.8 47.8 3.9e-59 200.4 47.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TMEM141 PF15110.6 EGG24018.1 - 0.34 11.5 1.6 1.7 9.3 0.1 2.6 2 0 0 2 2 2 0 TMEM141 protein family PHO4 PF01384.20 EGG24018.1 - 0.46 9.5 13.4 25 3.8 13.3 2.6 1 1 0 1 1 1 0 Phosphate transporter family Mito_carr PF00153.27 EGG24019.1 - 3.8e-47 158.1 6.8 4.9e-17 61.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PseudoU_synth_1 PF01416.20 EGG24020.1 - 1.2e-30 106.2 0.0 4.7e-22 78.5 0.0 2.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase DUF4061 PF13270.6 EGG24020.1 - 0.002 18.4 0.9 0.0079 16.5 0.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) DUF1084 PF06454.11 EGG24021.1 - 2.6e-08 33.6 23.9 8.1e-08 32.0 23.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) DUF1084 PF06454.11 EGG24022.1 - 3.4e-08 33.2 24.4 1e-07 31.6 24.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Aldedh PF00171.22 EGG24023.1 - 2.9e-185 616.2 0.0 3.2e-185 616.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGG24023.1 - 0.042 13.3 0.1 1.3 8.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1487) Phospholip_B PF04916.13 EGG24025.1 - 4.4e-114 382.0 10.6 6e-61 206.6 0.2 2.7 2 1 1 3 3 3 2 Phospholipase B CH PF00307.31 EGG24025.1 - 1.2e-15 57.6 0.1 3.5e-15 56.1 0.1 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain SBF2 PF12335.8 EGG24025.1 - 5.2e-10 39.3 4.9 3.1e-09 36.8 4.8 2.4 1 1 0 1 1 1 1 Myotubularin protein DZR PF12773.7 EGG24025.1 - 0.0054 16.7 1.5 0.0054 16.7 1.5 3.3 3 0 0 3 3 3 2 Double zinc ribbon CAMSAP_CH PF11971.8 EGG24025.1 - 0.025 14.4 0.0 0.093 12.6 0.0 2.0 1 0 0 1 1 1 0 CAMSAP CH domain CDC24 PF06395.11 EGG24025.1 - 0.045 14.0 1.4 0.12 12.6 0.1 2.5 2 0 0 2 2 2 0 CDC24 Calponin FtsL PF04999.13 EGG24025.1 - 0.22 11.5 0.0 0.22 11.5 0.0 2.4 3 0 0 3 3 3 0 Cell division protein FtsL zinc_ribbon_15 PF17032.5 EGG24025.1 - 3.7 8.4 9.1 0.49 11.2 0.6 3.6 4 0 0 4 4 4 0 zinc-ribbon family Coiled PF05710.12 EGG24027.1 - 0.0029 18.4 0.2 0.0034 18.2 0.2 1.1 1 0 0 1 1 1 1 Coiled coil Acetyltransf_1 PF00583.25 EGG24028.1 - 7e-15 55.3 0.0 8.6e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGG24028.1 - 3.9e-10 39.8 0.1 5.5e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG24028.1 - 5.8e-10 39.5 0.2 9.2e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGG24028.1 - 3.4e-06 27.8 0.0 4.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGG24028.1 - 0.00072 19.6 0.1 0.0013 18.8 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EGG24028.1 - 0.01 16.0 0.5 0.014 15.5 0.5 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG24028.1 - 0.035 14.1 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DNA_pol3_a_NI PF14480.6 EGG24028.1 - 0.062 13.3 1.4 0.095 12.7 0.2 1.9 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus I Ras PF00071.22 EGG24030.1 - 6.8e-36 123.3 0.0 8.1e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG24030.1 - 8.6e-19 67.9 0.0 1.3e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG24030.1 - 1.9e-11 43.7 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG24030.1 - 0.0011 19.1 0.0 0.0028 17.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG24030.1 - 0.0036 17.2 0.5 0.43 10.5 0.2 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 EGG24030.1 - 0.0074 16.0 0.4 0.047 13.4 0.1 2.2 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 EGG24030.1 - 0.028 13.8 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_28 PF13521.6 EGG24030.1 - 0.047 13.9 0.5 0.099 12.9 0.2 1.7 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 EGG24032.1 - 1.6e-30 105.8 0.0 2.2e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG24032.1 - 2.2e-18 66.6 0.0 6e-18 65.2 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG24032.1 - 3.7e-10 39.5 0.0 5.9e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG24032.1 - 1.9e-06 27.9 0.1 4.4e-06 26.7 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGG24032.1 - 0.0002 20.8 0.1 0.00044 19.7 0.1 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGG24032.1 - 0.0044 16.9 0.4 1.6 8.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGG24032.1 - 0.059 12.9 0.2 0.69 9.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Ras PF00071.22 EGG24033.1 - 7.4e-24 84.2 0.0 9.3e-24 83.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG24033.1 - 4e-10 40.0 0.0 1.1e-09 38.5 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG24033.1 - 5.9e-05 22.6 0.0 7.4e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG24033.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Dicty_REP PF05086.12 EGG24034.1 - 0.0027 15.8 8.4 0.0027 15.8 8.4 2.1 2 0 0 2 2 2 1 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 EGG24034.1 - 0.0077 16.2 49.0 0.031 14.3 14.7 2.2 2 0 0 2 2 2 2 Mucin-like glycoprotein Paramyxo_ncap PF00973.19 EGG24034.1 - 0.045 12.7 0.9 0.064 12.2 0.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Presenilin PF01080.17 EGG24034.1 - 0.081 11.7 3.2 0.086 11.6 3.2 1.2 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 EGG24034.1 - 0.22 11.9 8.5 0.029 14.8 2.7 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4834 PF16118.5 EGG24034.1 - 2 9.5 12.2 0.4 11.7 7.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4698 PF15769.5 EGG24034.1 - 5 6.1 10.1 0.21 10.6 4.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) SAM_Ste50p PF09235.10 EGG24035.1 - 0.0089 16.2 0.1 0.015 15.6 0.1 1.3 1 0 0 1 1 1 1 Ste50p, sterile alpha motif AAA_22 PF13401.6 EGG24036.1 - 0.00054 20.2 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG24036.1 - 0.0012 19.3 0.0 0.0035 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EGG24036.1 - 0.0022 18.0 0.0 0.0048 16.8 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGG24036.1 - 0.013 15.9 1.9 0.033 14.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain DUF4533 PF15047.6 EGG24036.1 - 0.051 13.1 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) Med31 PF05669.12 EGG24037.1 - 0.032 14.2 0.2 0.093 12.7 0.2 1.8 1 0 0 1 1 1 0 SOH1 Pkinase PF00069.25 EGG24039.1 - 2.9e-80 269.4 0.0 3.3e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG24039.1 - 8.8e-35 120.2 0.0 1.3e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGG24039.1 - 0.00012 21.2 0.1 0.0016 17.4 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGG24039.1 - 0.0049 16.2 0.1 0.045 13.1 0.0 2.2 2 1 1 3 3 3 1 Kinase-like APH PF01636.23 EGG24039.1 - 0.0085 16.0 0.0 0.025 14.5 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGG24039.1 - 0.0091 15.4 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_3 PF07725.12 EGG24039.1 - 0.064 13.1 0.1 0.19 11.6 0.1 1.9 1 0 0 1 1 1 0 Leucine Rich Repeat Seadorna_VP7 PF07387.11 EGG24039.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FERM_M PF00373.18 EGG24040.1 - 8.7e-20 71.3 0.1 3.4e-19 69.4 0.1 2.1 1 0 0 1 1 1 1 FERM central domain LRR_6 PF13516.6 EGG24040.1 - 1.2e-08 34.4 46.4 0.062 13.4 0.2 12.1 13 0 0 13 13 13 5 Leucine Rich repeat FERM_N PF09379.10 EGG24040.1 - 3.9e-07 29.9 0.0 1.7e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 FERM N-terminal domain LRR_4 PF12799.7 EGG24040.1 - 0.0054 17.1 0.4 0.0054 17.1 0.4 10.6 8 2 2 11 11 10 2 Leucine Rich repeats (2 copies) GvpG PF05120.12 EGG24040.1 - 0.031 14.3 1.0 0.22 11.6 1.0 2.5 1 0 0 1 1 1 0 Gas vesicle protein G DUF3135 PF11333.8 EGG24040.1 - 0.048 13.9 2.0 81 3.6 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) Terminase_3 PF04466.13 EGG24040.1 - 0.1 12.1 1.8 8.3 5.9 0.0 3.2 3 1 0 3 3 3 0 Phage terminase large subunit DUF3439 PF11921.8 EGG24040.1 - 0.72 9.8 7.8 2.8 7.9 7.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Rxt3 PF08642.10 EGG24040.1 - 1.3 9.8 6.1 35 5.2 6.1 3.0 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 CENP-B_dimeris PF09026.10 EGG24040.1 - 3 8.3 6.9 3 8.3 4.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pox_RNA_Pol_19 PF05320.12 EGG24040.1 - 7.7 6.5 11.7 0.59 10.1 5.0 2.6 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Dickkopf_N PF04706.12 EGG24041.1 - 0.015 15.8 1.3 0.015 15.8 1.3 7.6 7 1 0 7 7 7 0 Dickkopf N-terminal cysteine-rich region DUF1180 PF06679.12 EGG24041.1 - 0.77 10.1 3.0 1.5 9.2 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Acetyltransf_1 PF00583.25 EGG24042.1 - 3e-10 40.4 0.0 4.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EGG24042.1 - 1.2e-08 35.1 0.0 0.0014 18.7 0.0 2.1 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGG24042.1 - 1.5e-07 31.7 0.0 2.9e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG24042.1 - 6e-05 23.0 0.0 0.0022 17.9 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EGG24042.1 - 0.061 13.0 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 MOZ/SAS family FR47 PF08445.10 EGG24042.1 - 0.088 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein SET PF00856.28 EGG24043.1 - 2.5e-09 37.8 0.0 2.1e-08 34.7 0.0 2.4 1 1 0 1 1 1 1 SET domain RNA_pol_I_A49 PF06870.12 EGG24043.1 - 0.0053 15.7 0.1 0.0082 15.1 0.1 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor mRNA_stabil PF13929.6 EGG24043.1 - 0.11 11.4 3.4 0.77 8.7 1.5 2.3 2 0 0 2 2 2 0 mRNA stabilisation Transpos_assoc PF13963.6 EGG24043.1 - 0.12 12.7 0.2 0.29 11.5 0.2 1.6 1 0 0 1 1 1 0 Transposase-associated domain Chlorovi_GP_rpt PF06598.11 EGG24044.1 - 4 7.6 23.6 32 4.7 0.3 6.6 5 0 0 5 5 5 0 Chlorovirus glycoprotein repeat Gp5_C PF06715.12 EGG24044.1 - 4.5 7.6 6.5 26 5.2 0.0 3.9 4 0 0 4 4 4 0 Gp5 C-terminal repeat (3 copies) Anoctamin PF04547.12 EGG24045.1 - 0.0071 15.2 0.0 0.0088 14.9 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel NapE PF06796.11 EGG24045.1 - 1.6 8.3 4.8 7.8 6.1 3.3 2.2 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE COesterase PF00135.28 EGG24046.1 - 2.6e-106 356.5 0.9 3.2e-106 356.2 0.9 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGG24046.1 - 6.6e-09 35.9 0.0 1.3e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGG24046.1 - 0.031 13.1 0.2 0.12 11.2 0.2 1.8 1 1 0 1 1 1 0 Steryl acetyl hydrolase IF3_N PF05198.16 EGG24047.1 - 7.9e-13 48.5 0.4 2.7e-12 46.8 0.4 2.0 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 EGG24047.1 - 1.5e-08 34.4 0.2 6.2e-08 32.5 0.2 2.0 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain TagA PF12561.8 EGG24047.1 - 0.091 13.2 1.3 0.34 11.3 1.3 1.9 1 0 0 1 1 1 0 ToxR activated gene A lipoprotein domain Sigma54_activ_2 PF14532.6 EGG24047.1 - 0.16 12.1 0.4 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Coiled PF05710.12 EGG24049.1 - 0.021 15.6 5.2 0.024 15.5 5.2 1.1 1 0 0 1 1 1 0 Coiled coil dsrm PF00035.26 EGG24050.1 - 0.005 17.5 0.1 0.012 16.3 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EGG24050.1 - 0.013 15.8 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Coiled PF05710.12 EGG24051.1 - 0.0046 17.8 3.5 0.0064 17.3 3.5 1.3 1 0 0 1 1 1 1 Coiled coil Polysacc_deac_3 PF15421.6 EGG24051.1 - 0.011 14.3 0.0 0.013 14.0 0.0 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase DUF5404 PF17397.2 EGG24052.1 - 0.13 12.5 0.1 0.14 12.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5404) GTP_cyclohydroI PF01227.22 EGG24053.1 - 1.7e-74 249.1 0.2 2.3e-74 248.7 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EGG24053.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein FERM_F1 PF18379.1 EGG24054.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 FERM F1 ubiquitin-like domain DUF2677 PF10838.8 EGG24055.1 - 0.0041 17.1 0.1 0.0041 17.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2677) CBP PF12192.8 EGG24055.1 - 0.027 14.7 0.0 0.03 14.5 0.0 1.0 1 0 0 1 1 1 0 Fungal calcium binding protein Na_trans_assoc PF06512.13 EGG24056.1 - 2.4e-06 28.0 14.9 0.32 11.2 0.0 3.8 2 1 0 2 2 2 2 Sodium ion transport-associated CLN5 PF15014.6 EGG24057.1 - 5.1e-34 118.3 8.4 1e-33 117.3 8.4 1.4 1 1 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 PI3_PI4_kinase PF00454.27 EGG24058.1 - 1.9e-55 188.4 0.1 2.2e-54 184.9 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGG24058.1 - 3.6e-54 183.0 0.6 8.6e-54 181.8 0.6 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 EGG24058.1 - 3.2e-23 82.2 0.0 3.2e-23 82.2 0.0 2.2 3 0 0 3 3 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 EGG24058.1 - 2.4e-15 56.6 0.0 7.1e-15 55.1 0.0 1.9 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain Paf1 PF03985.13 EGG24058.1 - 0.00059 18.9 10.6 0.00059 18.9 10.6 2.2 2 0 0 2 2 2 1 Paf1 CDC45 PF02724.14 EGG24058.1 - 0.22 9.8 18.3 0.23 9.7 9.2 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF2052 PF09747.9 EGG24058.1 - 0.28 11.3 24.1 0.1 12.7 12.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SDA1 PF05285.12 EGG24058.1 - 0.73 9.2 24.5 0.16 11.3 12.8 2.3 2 0 0 2 2 2 0 SDA1 DUF4746 PF15928.5 EGG24058.1 - 1.1 8.7 20.3 2.8 7.3 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Merozoite_SPAM PF07133.11 EGG24058.1 - 1.1 9.2 39.6 0.06 13.3 26.0 2.4 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) CPSF100_C PF13299.6 EGG24058.1 - 1.5 8.9 22.0 2.2 8.4 10.2 3.0 3 0 0 3 3 2 0 Cleavage and polyadenylation factor 2 C-terminal Mpp10 PF04006.12 EGG24058.1 - 3.3 6.0 36.2 0.16 10.4 21.6 2.2 2 0 0 2 2 2 0 Mpp10 protein CobT PF06213.12 EGG24058.1 - 5.8 6.2 31.6 0.28 10.5 12.3 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Coiled PF05710.12 EGG24059.1 - 0.0074 17.1 1.0 0.0086 16.9 1.0 1.1 1 0 0 1 1 1 1 Coiled coil LRR_8 PF13855.6 EGG24060.1 - 6.3e-35 118.7 69.1 2.1e-07 30.6 10.7 8.3 3 2 7 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 EGG24060.1 - 2e-26 91.6 82.3 0.00082 19.7 0.4 10.1 7 3 3 10 10 10 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGG24060.1 - 1.8e-10 40.6 32.2 0.00046 19.7 3.3 5.3 1 1 3 5 5 5 4 Leucine-rich repeat Nic96 PF04097.14 EGG24060.1 - 5.6e-05 21.8 1.4 8.7e-05 21.2 1.4 1.2 1 0 0 1 1 1 1 Nup93/Nic96 SAND PF01342.21 EGG24061.1 - 0.0092 15.7 0.5 11 5.8 0.0 3.7 2 2 2 4 4 4 1 SAND domain Spore_III_AB PF09548.10 EGG24061.1 - 0.13 12.4 3.3 0.11 12.6 2.1 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF2845 PF11006.8 EGG24061.1 - 0.34 11.0 5.1 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2845) Apolipoprotein PF01442.18 EGG24063.1 - 5.1e-22 78.7 20.0 2.8e-09 37.1 1.7 5.4 3 3 1 4 4 4 4 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EGG24063.1 - 5.5e-07 30.1 32.1 0.2 12.2 1.2 9.6 5 3 5 11 11 11 5 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 EGG24063.1 - 2.8e-06 27.5 59.2 7e-05 23.0 4.2 7.4 3 3 3 7 7 7 5 Apolipophorin-III precursor (apoLp-III) CVNH PF08881.10 EGG24063.1 - 0.01 16.5 0.0 0.32 11.7 0.0 3.3 2 1 1 3 3 3 0 CVNH domain YtxH PF12732.7 EGG24063.1 - 0.047 14.2 65.1 0.69 10.5 4.3 11.6 4 3 3 7 7 7 0 YtxH-like protein Sterol_MT_C PF08498.10 EGG24063.1 - 0.42 10.9 1.2 42 4.5 0.0 4.0 4 0 0 4 4 4 0 Sterol methyltransferase C-terminal DUF885 PF05960.11 EGG24063.1 - 1.2 8.7 11.5 0.24 11.0 0.8 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF885) Ras PF00071.22 EGG24064.1 - 2.5e-58 196.2 0.0 3e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG24064.1 - 1.7e-19 70.2 0.0 2.3e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG24064.1 - 6.4e-10 38.8 0.0 7.3e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG24064.1 - 2e-06 27.5 0.3 5.5e-06 26.1 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGG24064.1 - 0.00034 20.5 0.0 0.4 10.6 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGG24064.1 - 0.026 14.1 0.0 0.043 13.3 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B YojJ PF10372.9 EGG24067.1 - 0.01 15.9 0.5 0.2 11.8 0.1 2.1 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Lactamase_B_2 PF12706.7 EGG24069.1 - 1.6e-14 53.9 0.0 5e-10 39.2 0.1 3.0 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EGG24069.1 - 4.7e-12 45.4 0.0 1.1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease DUF2745 PF10922.8 EGG24069.1 - 0.13 12.6 0.1 0.32 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2745) 5_nucleotid PF05761.14 EGG24070.1 - 4e-144 480.9 8.2 5.6e-144 480.5 8.2 1.2 1 0 0 1 1 1 1 5' nucleotidase family FAM212 PF15342.6 EGG24070.1 - 0.11 12.3 0.0 0.4 10.5 0.0 1.9 1 0 0 1 1 1 0 FAM212 family SSP160 PF06933.11 EGG24071.1 - 1.8 6.6 9.8 2.8 6.0 9.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF2975 PF11188.8 EGG24071.1 - 4 7.3 13.1 25 4.8 13.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) Mucin PF01456.17 EGG24071.1 - 4 7.4 16.3 8.4 6.4 16.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3135 PF11333.8 EGG24072.1 - 1 9.6 3.5 13 6.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) ORC4_C PF14629.6 EGG24073.1 - 2.3e-15 56.6 0.8 3.9e-15 55.8 0.8 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EGG24073.1 - 6.9e-09 36.3 0.1 2.1e-08 34.7 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 EGG24073.1 - 2.6e-07 31.2 0.1 8.5e-07 29.5 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGG24073.1 - 2.1e-06 28.0 0.9 4.2e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EGG24073.1 - 2.3e-05 24.5 1.7 2.3e-05 24.5 1.7 2.5 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea cobW PF02492.19 EGG24073.1 - 2.8e-05 23.8 0.3 0.00036 20.2 0.0 2.4 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EGG24073.1 - 3.7e-05 23.3 1.1 0.00088 18.8 0.0 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_33 PF13671.6 EGG24073.1 - 3.8e-05 23.9 0.3 0.0028 17.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 EGG24073.1 - 5.2e-05 23.6 0.5 9.2e-05 22.8 0.4 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EGG24073.1 - 9.7e-05 22.3 0.1 0.00023 21.1 0.1 1.6 1 0 0 1 1 1 1 NTPase NACHT PF05729.12 EGG24073.1 - 0.00012 22.0 1.0 0.03 14.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 EGG24073.1 - 0.0002 21.2 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EGG24073.1 - 0.00028 20.2 0.0 0.00049 19.4 0.0 1.6 1 1 0 1 1 1 1 KAP family P-loop domain G-alpha PF00503.20 EGG24073.1 - 0.00031 20.0 0.4 0.00062 19.0 0.1 1.5 1 1 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.27 EGG24073.1 - 0.00036 21.1 0.2 0.0022 18.5 0.0 2.1 2 0 0 2 2 2 1 ABC transporter DUF815 PF05673.13 EGG24073.1 - 0.00046 19.4 0.0 0.00089 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.6 EGG24073.1 - 0.0011 19.4 0.4 0.0041 17.5 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGG24073.1 - 0.0013 18.8 0.1 0.0013 18.8 0.1 2.4 4 0 0 4 4 2 1 AAA domain T2SSE PF00437.20 EGG24073.1 - 0.0018 17.4 0.0 0.0042 16.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 EGG24073.1 - 0.0019 18.7 2.5 0.0061 17.1 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 EGG24073.1 - 0.0023 17.7 0.3 0.0059 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA12 PF10443.9 EGG24073.1 - 0.0037 16.1 0.0 0.008 15.0 0.0 1.5 1 0 0 1 1 1 1 RNA12 protein AAA_11 PF13086.6 EGG24073.1 - 0.0046 16.8 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EGG24073.1 - 0.0048 16.3 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 KaiC KTI12 PF08433.10 EGG24073.1 - 0.0051 16.3 0.1 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 EGG24073.1 - 0.0053 16.5 0.1 0.0053 16.5 0.1 2.1 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 EGG24073.1 - 0.0058 16.6 0.1 0.029 14.3 0.0 2.1 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EGG24073.1 - 0.0075 16.2 1.5 0.0085 16.0 0.0 1.9 3 0 0 3 3 1 1 Rad17 P-loop domain TsaE PF02367.17 EGG24073.1 - 0.009 16.0 0.0 0.081 12.9 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EGG24073.1 - 0.012 16.1 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EGG24073.1 - 0.017 14.9 1.8 0.033 14.0 0.0 2.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 EGG24073.1 - 0.03 13.5 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain SRPRB PF09439.10 EGG24073.1 - 0.032 13.7 1.0 0.51 9.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.12 EGG24073.1 - 0.035 13.4 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.12 EGG24073.1 - 0.037 13.8 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 EGG24073.1 - 0.047 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 EGG24073.1 - 0.057 13.8 0.1 0.25 11.7 0.0 2.2 2 0 0 2 2 1 0 RNA helicase Viral_helicase1 PF01443.18 EGG24073.1 - 0.058 13.1 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 EGG24073.1 - 0.078 13.1 0.0 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain MeaB PF03308.16 EGG24073.1 - 0.17 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TIP120 PF08623.10 EGG24074.1 - 3e-54 183.3 0.1 3e-54 183.3 0.1 5.5 6 2 1 8 8 8 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EGG24074.1 - 6e-16 58.6 2.1 0.022 15.2 0.0 8.6 6 1 2 8 8 8 2 HEAT repeats HEAT PF02985.22 EGG24074.1 - 4.1e-15 54.6 16.4 0.72 10.3 0.1 12.9 14 0 0 14 14 14 3 HEAT repeat HEAT_EZ PF13513.6 EGG24074.1 - 6.5e-09 36.1 4.2 5.5 7.6 0.0 8.8 9 0 0 9 9 8 3 HEAT-like repeat Arm PF00514.23 EGG24074.1 - 1.6e-05 24.7 2.7 3.8 7.7 0.1 5.5 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat UME PF08064.13 EGG24074.1 - 0.00027 20.8 18.0 1.2 9.1 0.6 7.3 7 2 2 9 9 9 2 UME (NUC010) domain DUF3385 PF11865.8 EGG24074.1 - 0.0011 18.9 18.3 0.21 11.5 0.0 6.9 6 3 1 7 7 7 1 Domain of unknown function (DUF3385) TAF6_C PF07571.13 EGG24074.1 - 0.0068 16.7 0.9 0.15 12.4 0.0 3.9 4 1 0 4 4 3 1 TAF6 C-terminal HEAT repeat domain RTP1_C1 PF10363.9 EGG24074.1 - 0.032 14.4 14.2 0.27 11.4 0.2 6.2 8 1 0 8 8 7 0 Required for nuclear transport of RNA pol II C-terminus 1 FANCI_S2 PF14676.6 EGG24074.1 - 0.036 14.4 10.0 0.63 10.3 0.1 4.6 4 0 0 4 4 4 0 FANCI solenoid 2 Vac14_Fab1_bd PF12755.7 EGG24074.1 - 0.037 14.6 10.5 7.1 7.3 0.1 7.2 9 2 1 10 10 8 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.8 EGG24074.1 - 0.17 12.0 11.7 14 5.9 0.3 6.9 7 1 1 8 8 8 0 V-ATPase subunit H SDA1 PF05285.12 EGG24074.1 - 0.63 9.4 6.3 1 8.7 6.3 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EGG24074.1 - 1.7 7.9 4.8 3.9 6.7 4.8 1.5 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 EGG24074.1 - 3.2 7.6 12.6 0.7 9.7 8.2 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region TPR_MLP1_2 PF07926.12 EGG24076.1 - 0.91 9.6 89.1 0.057 13.5 16.5 4.8 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EGG24076.1 - 3.2 7.8 85.2 0.21 11.6 28.4 5.8 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3430 PF11912.8 EGG24077.1 - 1e-06 29.0 4.2 1e-06 29.0 4.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3430) IKI3 PF04762.12 EGG24079.1 - 3.6e-213 710.4 0.2 1.8e-171 572.3 0.0 2.4 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 EGG24079.1 - 0.004 17.4 0.2 15 5.9 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EGG24079.1 - 0.17 11.8 3.5 5.9 6.8 0.2 3.6 2 2 2 4 4 4 0 Region in Clathrin and VPS FeThRed_A PF02941.15 EGG24080.1 - 0.0034 17.5 0.0 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase variable alpha chain OTU PF02338.19 EGG24080.1 - 0.14 12.7 0.2 0.14 12.7 0.2 1.3 1 1 0 1 1 1 0 OTU-like cysteine protease AA_permease_2 PF13520.6 EGG24082.1 - 2.4e-60 204.6 42.2 2.4e-60 204.6 42.2 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGG24082.1 - 1.9e-40 138.9 39.2 1.9e-40 138.9 39.2 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 EGG24082.1 - 1.7e-20 72.8 8.8 1.7e-20 72.8 8.8 3.8 4 0 0 4 4 4 1 C-terminus of AA_permease DUF3493 PF11998.8 EGG24082.1 - 0.049 13.8 2.8 6.4 7.0 0.9 3.1 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 Antimicrobial22 PF16047.5 EGG24082.1 - 0.19 11.6 2.8 0.59 10.1 2.8 1.9 1 0 0 1 1 1 0 Frog antimicrobial peptide Saw1 PF11561.8 EGG24084.1 - 0.095 12.2 9.6 0.58 9.6 3.7 2.1 2 0 0 2 2 2 0 Single strand annealing-weakened 1 TIMELESS PF04821.14 EGG24084.1 - 0.29 10.4 5.7 0.033 13.5 1.2 1.6 2 0 0 2 2 2 0 Timeless protein Cwf_Cwc_15 PF04889.12 EGG24084.1 - 3 7.5 24.3 0.068 12.9 12.4 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3381 PF11861.8 EGG24084.1 - 3.4 7.4 17.4 0.17 11.7 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) PPL5 PF18168.1 EGG24084.1 - 4.2 6.6 11.0 0.39 10.0 3.2 2.1 2 0 0 2 2 2 0 Prim-pol family 5 Kdo PF06293.14 EGG24085.1 - 1e-06 28.3 0.1 0.0029 17.0 0.0 3.0 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGG24085.1 - 0.0015 18.2 0.1 0.17 11.5 0.1 2.3 1 1 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EGG24085.1 - 0.0016 17.8 0.2 0.0028 17.1 0.2 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG24085.1 - 0.0054 16.0 0.1 0.0078 15.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGG24085.1 - 0.017 15.0 0.0 8.5 6.2 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Secretin_N_2 PF07655.13 EGG24085.1 - 0.021 15.4 5.9 0.038 14.5 5.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain NST1 PF13945.6 EGG24086.1 - 2.1 8.4 14.0 3.5 7.7 14.0 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator NINJA_B PF16136.5 EGG24086.1 - 3.3 8.1 6.7 2 8.8 4.1 1.8 2 0 0 2 2 2 0 Putative nuclear localisation signal Menin PF05053.13 EGG24086.1 - 7.2 4.8 8.6 9 4.5 8.6 1.1 1 0 0 1 1 1 0 Menin TPR_12 PF13424.6 EGG24087.1 - 0.0017 18.6 8.8 4.3 7.7 4.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat HTH_Bact PF18768.1 EGG24087.1 - 0.051 13.2 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix bacterial domain HTH_19 PF12844.7 EGG24087.1 - 0.31 11.1 2.7 1.1 9.3 0.8 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain TPR_8 PF13181.6 EGG24087.1 - 1.1 9.7 15.5 0.86 10.0 0.3 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat ABC_membrane PF00664.23 EGG24088.1 - 2.3e-68 230.8 44.2 1.8e-39 136.1 22.2 2.8 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGG24088.1 - 1.2e-45 155.4 0.7 1.5e-24 87.1 0.0 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EGG24088.1 - 3.1e-09 36.6 5.1 0.046 13.2 0.7 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGG24088.1 - 5.1e-06 26.1 0.9 0.14 11.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EGG24088.1 - 8.5e-05 22.4 0.3 0.29 10.8 0.0 3.1 3 1 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 EGG24088.1 - 0.00073 19.6 3.7 0.084 13.0 0.1 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EGG24088.1 - 0.0014 18.5 1.0 1.5 8.5 0.4 3.4 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGG24088.1 - 0.002 18.4 0.9 0.77 10.0 0.2 3.1 2 0 0 2 2 2 1 AAA domain CDC45 PF02724.14 EGG24088.1 - 0.0029 16.0 0.0 0.0043 15.4 0.0 1.2 1 0 0 1 1 1 1 CDC45-like protein ATP_bind_1 PF03029.17 EGG24088.1 - 0.006 16.4 0.5 1.2 8.8 0.2 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EGG24088.1 - 0.0064 16.9 0.1 2.8 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EGG24088.1 - 0.0075 16.8 0.3 2.2 8.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 EGG24088.1 - 0.031 13.5 0.3 4.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EGG24088.1 - 0.04 13.8 8.3 0.34 10.8 0.8 3.4 3 1 0 3 3 3 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 EGG24088.1 - 0.041 13.2 0.2 5.7 6.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 EGG24088.1 - 0.043 13.9 0.9 0.12 12.4 0.2 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 EGG24088.1 - 0.15 12.5 15.0 4.7 7.7 0.0 4.1 4 0 0 4 4 4 0 AAA domain AAA_7 PF12775.7 EGG24088.1 - 0.18 11.3 2.6 7.5 6.0 0.1 3.0 3 0 0 3 3 3 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EGG24088.1 - 0.26 11.0 3.8 5.6 6.7 0.2 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EGG24088.1 - 0.52 10.4 7.9 2.7 8.0 0.2 3.4 3 0 0 3 3 3 0 Dynamin family DUF2207 PF09972.9 EGG24088.1 - 1.1 8.0 24.6 0.43 9.3 0.2 4.6 2 2 1 3 3 3 0 Predicted membrane protein (DUF2207) NB-ARC PF00931.22 EGG24088.1 - 2 7.5 5.8 12 4.9 0.0 3.0 4 0 0 4 4 4 0 NB-ARC domain Mit_KHE1 PF10173.9 EGG24088.1 - 5.9 6.9 11.2 0.14 12.2 0.5 2.9 3 0 0 3 3 3 0 Mitochondrial K+-H+ exchange-related Roc PF08477.13 EGG24088.1 - 9.3 6.5 9.5 14 6.0 0.2 4.3 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase Fer2 PF00111.27 EGG24089.1 - 3.1e-14 52.7 0.1 5.7e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 EGG24089.1 - 0.076 13.1 0.6 0.33 11.0 0.2 2.2 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain RNF111_N PF15303.6 EGG24089.1 - 0.16 11.7 8.8 0.33 10.7 8.7 1.5 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus Ank_2 PF12796.7 EGG24090.1 - 2.3e-17 63.3 8.4 3.2e-06 27.6 0.0 6.9 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24090.1 - 1.8e-15 57.1 10.6 0.016 15.8 0.1 10.8 7 2 3 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24090.1 - 4.4e-09 35.9 0.5 2.5 9.0 0.0 8.9 13 0 0 13 13 13 2 Ankyrin repeat Ank_5 PF13857.6 EGG24090.1 - 6.8e-08 32.6 6.8 2.1 8.7 0.0 9.6 7 2 5 12 12 12 2 Ankyrin repeats (many copies) Ank PF00023.30 EGG24090.1 - 0.0023 18.3 0.0 13 6.5 0.0 5.7 6 1 0 6 6 6 1 Ankyrin repeat DUF4074 PF13293.6 EGG24090.1 - 0.068 13.5 0.3 0.17 12.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4074) fn3 PF00041.21 EGG24091.1 - 0.00022 21.5 8.2 2.1 8.8 0.1 4.5 3 1 0 3 3 3 3 Fibronectin type III domain EGF_2 PF07974.13 EGG24091.1 - 0.00053 20.3 16.1 0.0019 18.6 16.1 2.0 1 0 0 1 1 1 1 EGF-like domain ObR_Ig PF18589.1 EGG24091.1 - 0.02 15.3 0.1 0.52 10.7 0.0 2.8 2 0 0 2 2 2 0 Obesity receptor immunoglobulin like domain Pap_E4 PF02711.14 EGG24091.1 - 0.059 14.3 0.1 0.23 12.5 0.1 2.0 1 1 0 1 1 1 0 E4 protein HU-DNA_bdg PF14848.6 EGG24091.1 - 0.096 12.7 0.1 11 6.0 0.0 3.3 3 1 1 4 4 4 0 DNA-binding domain hEGF PF12661.7 EGG24091.1 - 0.77 10.5 9.3 3.7 8.3 9.3 2.4 1 0 0 1 1 1 0 Human growth factor-like EGF I-EGF_1 PF18372.1 EGG24091.1 - 7.6 6.7 12.4 0.56 10.3 6.5 2.3 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 EGG24092.1 - 9.3e-05 22.7 15.9 0.00036 20.8 15.9 2.1 1 0 0 1 1 1 1 EGF-like domain I-EGF_1 PF18372.1 EGG24092.1 - 0.18 11.9 8.7 0.79 9.9 8.7 2.2 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 hEGF PF12661.7 EGG24092.1 - 2.3 9.0 9.5 11 6.8 9.5 2.4 1 0 0 1 1 1 0 Human growth factor-like EGF ecTbetaR2 PF08917.10 EGG24092.1 - 8.1 6.4 9.8 0.14 12.1 0.5 2.9 3 0 0 3 3 3 0 Transforming growth factor beta receptor 2 ectodomain Ank_2 PF12796.7 EGG24093.1 - 9.2e-25 87.1 4.3 6.7e-07 29.8 0.1 6.1 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24093.1 - 1.5e-16 60.5 3.4 0.011 16.3 0.1 8.3 7 2 2 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24093.1 - 1.1e-13 50.0 0.4 0.73 10.6 0.0 11.5 13 0 0 13 13 13 1 Ankyrin repeat Ank_5 PF13857.6 EGG24093.1 - 5.4e-09 36.1 0.2 0.25 11.7 0.0 8.3 8 1 2 10 10 10 1 Ankyrin repeats (many copies) Ank PF00023.30 EGG24093.1 - 0.0066 16.8 5.7 67 4.2 0.1 7.0 9 0 0 9 9 9 0 Ankyrin repeat Ank_2 PF12796.7 EGG24094.1 - 2.5e-21 76.0 11.6 1.9e-06 28.4 0.1 7.4 4 2 4 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24094.1 - 5.9e-11 42.7 7.0 0.017 15.7 0.1 9.0 9 2 2 11 11 11 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24094.1 - 1.4e-08 34.8 7.6 0.28 11.6 0.0 10.0 10 1 2 12 12 12 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24094.1 - 4.1e-08 32.9 20.9 2.8 8.8 0.0 13.1 17 0 0 17 17 17 1 Ankyrin repeat DUF3447 PF11929.8 EGG24094.1 - 2.4e-06 27.4 22.8 0.3 11.1 2.4 8.6 5 4 4 10 10 10 4 Domain of unknown function (DUF3447) DsrC PF04358.13 EGG24094.1 - 0.22 12.1 1.0 7 7.2 0.0 3.7 4 1 1 5 5 5 0 DsrC like protein Ank PF00023.30 EGG24094.1 - 0.24 11.9 8.6 88 3.8 0.0 7.1 7 1 0 7 7 7 0 Ankyrin repeat AbiJ_NTD4 PF18863.1 EGG24094.1 - 0.33 11.4 4.8 0.27 11.7 0.7 2.7 3 0 0 3 3 3 0 AbiJ N-terminal domain 4 Peptidase_C26 PF07722.13 EGG24095.1 - 2.6e-11 43.7 0.0 1.6e-08 34.6 0.0 2.7 2 0 0 2 2 2 2 Peptidase C26 GATase PF00117.28 EGG24095.1 - 2.2e-06 27.6 5.4 0.00013 21.8 0.0 3.2 3 0 0 3 3 3 1 Glutamine amidotransferase class-I TAF4 PF05236.14 EGG24095.1 - 0.00075 19.3 10.5 0.0013 18.5 10.5 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Merozoite_SPAM PF07133.11 EGG24095.1 - 0.0043 17.1 14.3 0.0092 16.0 14.3 1.5 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) CDC45 PF02724.14 EGG24095.1 - 0.029 12.7 9.2 0.036 12.4 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 EGG24095.1 - 0.05 13.0 11.4 0.086 12.2 11.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2052 PF09747.9 EGG24095.1 - 0.16 12.1 22.2 0.15 12.1 15.3 2.5 3 0 0 3 3 2 0 Coiled-coil domain containing protein (DUF2052) NPR3 PF03666.13 EGG24095.1 - 0.21 10.3 10.1 0.42 9.3 10.1 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 EGG24095.1 - 0.32 10.1 2.4 0.43 9.7 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 EGG24095.1 - 0.51 10.1 16.4 0.95 9.2 16.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM76 PF16046.5 EGG24095.1 - 0.61 9.4 12.5 1.1 8.6 8.5 2.2 2 0 0 2 2 2 0 FAM76 protein Presenilin PF01080.17 EGG24095.1 - 0.71 8.6 13.2 1.1 8.0 13.2 1.2 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 EGG24095.1 - 0.73 9.2 11.8 1.5 8.3 11.8 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 EGG24095.1 - 1.2 8.0 14.4 2.4 7.0 14.4 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.7 EGG24095.1 - 1.2 7.2 7.2 1.7 6.7 7.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PTPRCAP PF15713.5 EGG24095.1 - 1.6 9.0 17.9 1.4 9.1 15.5 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RNA_pol_Rpc4 PF05132.14 EGG24095.1 - 1.9 8.9 8.6 4 7.8 8.6 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 PPL5 PF18168.1 EGG24095.1 - 2.2 7.5 7.8 4 6.6 7.8 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Paf1 PF03985.13 EGG24095.1 - 2.7 6.9 21.3 4.6 6.1 21.3 1.3 1 0 0 1 1 1 0 Paf1 DUF913 PF06025.12 EGG24095.1 - 3 6.8 6.9 5.1 6.0 6.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4834 PF16118.5 EGG24095.1 - 5.3 8.1 11.6 19 6.3 11.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Aldedh PF00171.22 EGG24096.1 - 5.9e-118 394.3 0.0 7.3e-118 394.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGG24096.1 - 0.0033 16.5 0.0 0.0053 15.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Not1 PF04054.15 EGG24097.1 - 1.4e-146 488.2 2.2 1.4e-146 488.2 2.2 2.8 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EGG24097.1 - 6.4e-85 284.1 4.5 6.4e-85 284.1 4.5 2.7 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 EGG24097.1 - 2.5e-64 216.0 1.8 2.5e-64 216.0 1.8 5.6 6 0 0 6 6 6 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 EGG24097.1 - 1.4e-54 184.0 0.5 1.4e-54 184.0 0.5 4.6 6 0 0 6 6 6 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 EGG24097.1 - 2.3e-31 108.9 3.6 2.3e-31 108.9 3.6 4.8 5 0 0 5 5 5 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Rap1a PF18602.1 EGG24097.1 - 5.7 7.3 7.2 10 6.5 0.1 3.4 2 0 0 2 2 2 0 Rap1a immunity proteins Secretin_N_2 PF07655.13 EGG24098.1 - 0.0076 16.8 11.6 0.0076 16.8 11.6 2.6 4 0 0 4 4 4 1 Secretin N-terminal domain Chorion_2 PF03964.15 EGG24098.1 - 0.075 13.9 4.6 0.17 12.7 4.6 1.6 1 0 0 1 1 1 0 Chorion family 2 CCDC24 PF15669.5 EGG24098.1 - 0.27 11.1 2.0 0.9 9.4 1.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family AF-4 PF05110.13 EGG24098.1 - 0.27 9.3 15.1 0.36 8.9 15.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF508 PF04370.12 EGG24098.1 - 3.3 7.4 12.3 0.57 9.9 6.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF508) DUF3446 PF11928.8 EGG24098.1 - 5.3 7.4 23.4 3.3 8.1 20.6 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain DnaJ PF00226.31 EGG24099.1 - 2.6e-19 69.1 2.4 4.4e-19 68.4 0.5 2.4 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.22 EGG24099.1 - 0.0074 16.1 0.2 0.16 11.8 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Selenoprotein_S PF06936.11 EGG24099.1 - 0.0099 15.7 10.8 0.021 14.7 10.2 1.9 2 0 0 2 2 2 1 Selenoprotein S (SelS) CDC45 PF02724.14 EGG24099.1 - 2.8 6.1 15.6 3.4 5.8 15.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DAGK_cat PF00781.24 EGG24100.1 - 3.8e-18 65.3 0.0 8.2e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ATP-synt_E PF05680.12 EGG24100.1 - 1.6 9.1 11.1 0.44 10.9 0.6 2.7 2 0 0 2 2 2 0 ATP synthase E chain YfiO PF13525.6 EGG24102.1 - 0.0033 17.2 1.1 0.0064 16.2 1.1 1.5 1 1 0 1 1 1 1 Outer membrane lipoprotein DUF4326 PF14216.6 EGG24102.1 - 0.04 14.6 0.6 0.33 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) Glutaredoxin2_C PF04399.13 EGG24102.1 - 0.049 13.5 2.3 0.28 11.0 0.1 2.1 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Exonuc_VII_L PF02601.15 EGG24102.1 - 1.1 8.8 4.1 1.2 8.7 4.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 EGG24102.1 - 1.5 7.3 6.8 1.7 7.2 6.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_33 PF13671.6 EGG24103.1 - 1.6e-07 31.6 0.0 2.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGG24103.1 - 3.4e-07 30.9 0.1 5.1e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGG24103.1 - 1.4e-06 28.7 0.0 2.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 EGG24103.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.6 1 1 0 1 1 1 1 Dephospho-CoA kinase Nfu_N PF08712.11 EGG24104.1 - 0.01 15.8 0.3 0.019 15.0 0.2 1.4 1 1 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal PHO4 PF01384.20 EGG24105.1 - 0.47 9.4 5.9 2.2 7.2 5.9 2.0 1 1 0 1 1 1 0 Phosphate transporter family Bromodomain PF00439.25 EGG24106.1 - 7.6e-18 64.4 4.6 8.7e-18 64.2 0.4 2.6 2 0 0 2 2 2 1 Bromodomain Na_trans_assoc PF06512.13 EGG24106.1 - 4.4e-05 23.9 0.0 4.4e-05 23.9 0.0 4.5 3 3 0 4 4 4 1 Sodium ion transport-associated MtrB PF05440.12 EGG24106.1 - 0.21 12.0 0.1 0.84 10.1 0.1 2.0 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B ApoO PF09769.9 EGG24106.1 - 3.3 7.7 11.0 15 5.6 0.6 3.2 2 0 0 2 2 2 0 Apolipoprotein O DUF569 PF04601.13 EGG24107.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF569) DUF2838 PF10998.8 EGG24108.1 - 1.3e-38 131.7 9.8 1.3e-38 131.7 9.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Nup54 PF13874.6 EGG24108.1 - 0.011 15.8 1.6 0.011 15.8 1.6 1.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 MFS_1 PF07690.16 EGG24109.1 - 7.4e-11 41.6 18.9 4.2e-10 39.1 17.7 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Holin_SPP1 PF04688.13 EGG24109.1 - 0.23 11.6 2.4 1.1 9.5 0.1 2.9 3 0 0 3 3 3 0 SPP1 phage holin PHO4 PF01384.20 EGG24109.1 - 6 5.8 10.6 15 4.5 10.6 1.9 1 1 0 1 1 1 0 Phosphate transporter family MatE PF01554.18 EGG24110.1 - 1.8e-59 200.0 30.3 1.4e-32 112.5 16.5 3.2 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 EGG24110.1 - 1.9e-06 28.0 11.3 1.9e-06 28.0 11.3 4.9 3 3 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain OppC_N PF12911.7 EGG24110.1 - 2.4 8.2 5.8 1 9.4 0.2 3.0 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Dzip-like_N PF13815.6 EGG24111.1 - 9e-11 41.8 0.7 9e-11 41.8 0.7 6.4 6 1 1 7 7 7 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal eIF3g PF12353.8 EGG24113.1 - 1.1e-20 74.3 4.9 1.8e-20 73.6 4.9 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EGG24113.1 - 9.9e-16 57.3 0.0 2.5e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) H_lectin PF09458.10 EGG24114.1 - 4.9e-25 87.5 1.7 9.7e-25 86.5 0.7 2.0 2 0 0 2 2 2 1 H-type lectin domain F5_F8_type_C PF00754.25 EGG24114.1 - 4.8e-21 75.2 1.7 4.8e-21 75.2 1.7 1.8 2 0 0 2 2 2 1 F5/8 type C domain Muskelin_N PF06588.11 EGG24114.1 - 0.0022 17.9 0.4 0.0033 17.4 0.4 1.4 1 0 0 1 1 1 1 Muskelin N-terminus ZirS_C PF16583.5 EGG24115.1 - 0.016 14.8 0.3 0.021 14.4 0.3 1.2 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain CNPase PF05881.12 EGG24115.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) EF-hand_1 PF00036.32 EGG24117.1 - 2.5e-37 123.6 14.9 2.2e-09 36.2 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGG24117.1 - 5.2e-33 113.3 3.5 1.1e-15 57.9 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGG24117.1 - 3.4e-31 106.9 11.2 6.7e-14 51.5 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGG24117.1 - 2.4e-26 89.4 10.5 8.8e-09 34.6 0.2 4.7 4 2 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EGG24117.1 - 3.5e-25 86.3 10.2 1e-06 28.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGG24117.1 - 1.6e-14 54.0 0.1 2.9e-09 37.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGG24117.1 - 2.9e-08 34.0 0.1 0.0022 18.3 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGG24117.1 - 2.9e-08 33.6 1.0 0.004 17.1 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 EGG24117.1 - 3.8e-06 26.8 0.3 0.028 14.4 0.0 2.8 2 2 1 3 3 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 EGG24117.1 - 0.00019 21.5 4.1 0.12 12.6 0.2 3.2 1 1 2 3 3 3 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 EGG24117.1 - 0.00022 21.3 0.9 0.0011 19.0 0.2 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.11 EGG24117.1 - 0.00023 20.8 3.6 0.00027 20.6 3.6 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 EGG24117.1 - 0.00086 20.0 0.5 1.4 9.8 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.16 EGG24117.1 - 0.0011 19.3 0.6 0.89 9.9 0.1 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb4 Caleosin PF05042.13 EGG24117.1 - 0.0014 18.6 1.0 1.2 9.1 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein Poly_export PF02563.16 EGG24117.1 - 0.0017 18.6 0.3 0.15 12.3 0.0 3.0 1 1 2 3 3 3 1 Polysaccharide biosynthesis/export protein EF-hand_11 PF08976.11 EGG24117.1 - 0.0058 17.5 0.0 0.78 10.7 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain DUF1296 PF06972.11 EGG24117.1 - 0.0086 16.2 1.9 0.52 10.5 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1296) SapB_1 PF05184.15 EGG24117.1 - 0.012 15.6 5.8 22 5.2 0.2 4.1 4 0 0 4 4 4 0 Saposin-like type B, region 1 DUF4497 PF14924.6 EGG24117.1 - 0.014 15.9 0.0 4.3 7.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) dCache_2 PF08269.11 EGG24117.1 - 0.021 14.0 0.1 1.1 8.3 0.1 2.2 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 EGG24117.1 - 0.022 14.9 0.4 0.35 11.0 0.1 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain TetR_C_7 PF14246.6 EGG24117.1 - 0.04 14.0 0.3 8.4 6.5 0.0 2.7 1 1 1 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Spore_III_AB PF09548.10 EGG24117.1 - 0.041 14.0 0.8 0.081 13.0 0.8 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RuvA_C PF07499.13 EGG24117.1 - 0.099 13.1 0.1 41 4.7 0.1 3.1 3 0 0 3 3 3 0 RuvA, C-terminal domain DED PF01335.21 EGG24117.1 - 0.21 11.9 3.3 1.4 9.3 0.1 2.7 3 1 0 3 3 3 0 Death effector domain MBOAT PF03062.19 EGG24118.1 - 6.9e-15 55.2 19.7 1.3e-14 54.3 19.5 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EGG24118.1 - 0.00091 19.4 7.1 0.018 15.3 1.0 3.4 2 1 0 3 3 3 2 Membrane bound O-acyl transferase family Nucleo_P87 PF07267.11 EGG24118.1 - 0.73 8.6 10.9 1.2 8.0 10.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PAP1 PF08601.10 EGG24118.1 - 3.1 7.4 25.8 4.4 6.9 25.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 TMEM135_C_rich PF15982.5 EGG24119.1 - 1e-20 74.7 0.6 1.8e-20 73.9 0.6 1.3 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 EGG24119.1 - 0.0061 16.9 1.1 0.012 16.0 0.9 1.6 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Imp-YgjV PF10688.9 EGG24119.1 - 0.018 14.9 0.7 0.027 14.3 0.7 1.3 1 0 0 1 1 1 0 Bacterial inner membrane protein ECF_trnsprt PF12822.7 EGG24119.1 - 0.041 14.0 2.6 0.052 13.6 2.6 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Protocadherin PF08374.11 EGG24120.1 - 0.026 14.5 0.0 0.075 13.0 0.0 1.7 1 0 0 1 1 1 0 Protocadherin Pkinase PF00069.25 EGG24123.1 - 2.5e-46 158.2 0.4 2.5e-46 158.2 0.4 3.1 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG24123.1 - 7.5e-22 77.9 8.6 8.5e-22 77.7 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.12 EGG24123.1 - 5.6e-07 29.6 0.7 5.6e-07 29.6 0.7 2.4 3 0 0 3 3 3 1 Mad3/BUB1 homology region 1 APH PF01636.23 EGG24123.1 - 0.02 14.8 2.6 0.051 13.5 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGG24123.1 - 0.026 14.1 0.4 0.026 14.1 0.4 2.5 2 0 0 2 2 2 0 RIO1 family Coiled PF05710.12 EGG24124.1 - 0.0027 18.5 3.6 0.0044 17.8 3.6 1.3 1 0 0 1 1 1 1 Coiled coil COPIIcoated_ERV PF07970.12 EGG24125.1 - 2.6e-50 171.3 0.3 2.6e-50 171.3 0.3 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGG24125.1 - 1.2e-21 76.8 0.8 4.6e-21 75.0 0.2 2.4 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SUIM_assoc PF16619.5 EGG24125.1 - 0.048 13.7 11.7 0.16 12.1 11.7 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Hydin_ADK PF17213.3 EGG24125.1 - 0.24 11.7 4.2 0.43 10.8 4.2 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF2722 PF10846.8 EGG24125.1 - 0.74 8.7 8.5 1.3 7.8 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med3 PF11593.8 EGG24125.1 - 5.2 6.2 11.3 10 5.2 11.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Activator_LAG-3 PF11498.8 EGG24125.1 - 9 5.1 19.2 16 4.3 19.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CHB_HEX_C PF03174.13 EGG24126.1 - 0.099 12.6 0.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain ATP-grasp_2 PF08442.10 EGG24128.1 - 1.4e-74 250.0 1.8 1.5e-74 249.9 0.8 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EGG24128.1 - 4.7e-26 91.4 1.6 8.5e-26 90.6 1.6 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EGG24128.1 - 2.7e-10 40.1 0.1 4.4e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EGG24128.1 - 0.00011 22.0 0.8 0.0012 18.7 0.1 2.4 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 EGG24128.1 - 0.071 12.9 0.2 0.72 9.6 0.2 2.2 1 1 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain DUF1327 PF07041.11 EGG24128.1 - 0.087 12.8 0.1 0.58 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1327) DUF4180 PF13788.6 EGG24130.1 - 0.0077 16.1 0.0 0.008 16.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4180) GTP1_OBG PF01018.22 EGG24133.1 - 2e-05 24.2 0.1 4.1e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 GTP1/OBG RVT_1 PF00078.27 EGG24134.1 - 3.2e-31 108.6 0.4 5.4e-31 107.8 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EGG24134.1 - 2.1e-16 59.8 0.0 5.2e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 EGG24134.1 - 3.9e-11 43.1 0.0 1.8e-10 41.0 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.26 EGG24134.1 - 4.3e-11 43.0 0.0 1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 EGG24134.1 - 2e-08 34.5 0.0 5.6e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 EGG24134.1 - 5.7e-06 26.1 0.1 1.2e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Nup188 PF10487.9 EGG24134.1 - 0.046 11.7 0.0 0.073 11.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 DUF5349 PF17298.2 EGG24135.1 - 0.17 11.6 6.0 0.22 11.3 6.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Mucin PF01456.17 EGG24135.1 - 0.42 10.6 16.5 0.64 10.0 16.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein TFIIF_alpha PF05793.12 EGG24135.1 - 0.44 9.1 7.0 0.55 8.8 7.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SSP160 PF06933.11 EGG24135.1 - 0.87 7.7 6.8 1.1 7.4 6.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MGC-24 PF05283.11 EGG24135.1 - 6.1 7.3 7.8 9.2 6.7 7.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin ubiquitin PF00240.23 EGG24137.1 - 3.5e-34 116.4 0.4 4.8e-34 115.9 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 EGG24137.1 - 1.1e-30 105.2 12.4 1.7e-30 104.7 12.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EGG24137.1 - 7.7e-16 57.7 0.4 1.1e-15 57.2 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGG24137.1 - 3.8e-05 24.0 0.1 0.00016 22.1 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EGG24137.1 - 0.0055 17.0 0.1 0.0096 16.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGG24137.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGG24137.1 - 0.019 15.1 0.0 0.043 13.9 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EGG24137.1 - 0.026 14.5 0.7 7.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 EGG24137.1 - 0.064 13.8 0.1 0.072 13.7 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Thioredoxin PF00085.20 EGG24138.1 - 9.2e-28 96.3 0.0 1e-14 54.4 0.1 2.8 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EGG24138.1 - 3.1e-05 24.4 0.5 0.038 14.4 0.1 4.2 4 1 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGG24138.1 - 3.9e-05 23.7 0.0 0.14 12.4 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EGG24138.1 - 0.024 14.9 4.0 12 6.3 0.0 4.8 5 0 0 5 5 5 0 Thioredoxin-like DUF3439 PF11921.8 EGG24138.1 - 0.26 11.2 5.0 0.55 10.2 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ank_2 PF12796.7 EGG24139.1 - 1.7e-24 86.2 8.8 7.9e-06 26.4 0.8 5.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24139.1 - 1.1e-21 76.9 12.3 0.0057 17.2 0.3 7.8 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24139.1 - 1.1e-19 70.2 11.6 0.019 15.3 0.0 9.7 3 2 6 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24139.1 - 2.1e-09 36.8 12.0 3.3 8.6 0.1 10.9 9 3 4 13 13 13 1 Ankyrin repeat Ribosomal_L30 PF00327.20 EGG24139.1 - 0.023 14.6 0.0 17 5.4 0.0 3.9 4 0 0 4 4 4 0 Ribosomal protein L30p/L7e Ank PF00023.30 EGG24139.1 - 0.023 15.1 6.4 26 5.5 0.1 5.9 5 2 0 5 5 5 0 Ankyrin repeat FIT1_2 PF17357.2 EGG24140.1 - 0.64 10.1 12.2 0.19 11.8 0.6 2.9 2 1 1 3 3 3 0 Facilitor Of iron transport 1 and 2 F_actin_bind PF08919.10 EGG24141.1 - 0.016 15.3 0.1 0.031 14.4 0.1 1.4 1 0 0 1 1 1 0 F-actin binding Ank_2 PF12796.7 EGG24142.1 - 3.3e-08 34.0 0.1 8.3e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG24142.1 - 0.00046 20.4 0.5 22 6.1 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EGG24142.1 - 0.00067 20.2 0.2 0.33 11.6 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24142.1 - 0.004 17.4 0.0 4 7.9 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) RVT_1 PF00078.27 EGG24143.1 - 0.023 14.2 0.0 0.03 13.9 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Myotub-related PF06602.14 EGG24144.1 - 2.9e-84 283.0 0.0 5.5e-84 282.1 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain COR PF16095.5 EGG24144.1 - 6.6e-57 192.5 0.3 1.4e-56 191.4 0.3 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Pkinase_Tyr PF07714.17 EGG24144.1 - 9.2e-52 175.9 0.0 4.3e-51 173.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGG24144.1 - 2.3e-40 138.6 0.0 7.1e-40 137.0 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 EGG24144.1 - 3.4e-30 103.6 50.3 2.8e-08 33.4 6.5 6.1 3 1 3 6 6 6 6 Leucine rich repeat Roc PF08477.13 EGG24144.1 - 2.4e-23 82.6 0.1 1.2e-22 80.4 0.2 2.3 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_4 PF12799.7 EGG24144.1 - 8.8e-21 73.7 54.2 8.8e-05 22.8 3.3 8.5 3 1 7 10 10 10 10 Leucine Rich repeats (2 copies) Ras PF00071.22 EGG24144.1 - 5.1e-13 48.9 0.1 1.8e-12 47.2 0.1 2.0 1 0 0 1 1 1 1 Ras family WD40 PF00400.32 EGG24144.1 - 1e-08 35.7 24.0 0.01 16.7 0.4 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Arf PF00025.21 EGG24144.1 - 2.5e-06 27.1 2.7 1.3e-05 24.8 0.8 2.8 2 1 0 2 2 2 1 ADP-ribosylation factor family ANAPC4_WD40 PF12894.7 EGG24144.1 - 0.00028 21.1 1.5 0.17 12.2 0.3 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 EGG24144.1 - 0.00029 21.1 0.0 1.5 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 EGG24144.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein MMR_HSR1 PF01926.23 EGG24144.1 - 0.0018 18.4 0.0 0.0045 17.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase LRR_9 PF14580.6 EGG24144.1 - 0.008 15.7 16.9 0.14 11.6 2.9 3.5 1 1 0 2 2 2 2 Leucine-rich repeat FERM_f0 PF16511.5 EGG24144.1 - 0.0082 16.4 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM RhoGAP PF00620.27 EGG24144.1 - 0.02 14.7 0.1 0.07 12.9 0.1 2.0 1 0 0 1 1 1 0 RhoGAP domain RA PF00788.23 EGG24144.1 - 0.046 14.4 0.0 0.19 12.4 0.0 2.0 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain APH PF01636.23 EGG24144.1 - 0.046 13.6 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA_24 PF13479.6 EGG24144.1 - 0.093 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG24144.1 - 0.15 12.4 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Adeno_E3_CR2 PF02439.15 EGG24146.1 - 1.4e-06 28.0 2.7 3.1e-06 26.8 2.7 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Insulin_TMD PF17870.1 EGG24146.1 - 0.018 15.1 3.8 0.033 14.3 3.8 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pheromone PF08015.11 EGG24146.1 - 0.66 11.1 3.7 0.3 12.2 0.8 1.9 2 0 0 2 2 2 0 Fungal mating-type pheromone Orf78 PF06024.12 EGG24146.1 - 9.3 6.6 13.8 2.6 8.4 2.8 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Tho1_MOS11_C PF18592.1 EGG24147.1 - 0.052 13.4 0.8 0.37 10.6 0.2 2.5 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain DUF1664 PF07889.12 EGG24147.1 - 0.15 12.1 7.3 0.054 13.5 2.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Abi_2 PF07751.11 EGG24147.1 - 3.9 7.7 15.1 2.5 8.3 10.8 2.1 1 1 0 2 2 2 0 Abi-like protein PQ-loop PF04193.14 EGG24148.1 - 5.8e-09 35.6 20.5 9.4e-05 22.1 7.2 2.5 2 0 0 2 2 2 2 PQ loop repeat Otopetrin PF03189.13 EGG24148.1 - 0.0025 16.7 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 Otopetrin Holin_BhlA PF10960.8 EGG24148.1 - 0.021 14.8 0.2 0.021 14.8 0.2 2.2 2 0 0 2 2 2 0 BhlA holin family SpoIIIAH PF12685.7 EGG24148.1 - 0.04 13.7 9.6 0.058 13.2 3.8 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Orthoreo_P10 PF07204.11 EGG24148.1 - 0.085 12.8 0.6 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 V_ATPase_I PF01496.19 EGG24148.1 - 0.15 10.0 0.0 0.27 9.1 0.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4231 PF14015.6 EGG24148.1 - 1 9.8 7.5 0.36 11.3 0.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF2304 PF10066.9 EGG24148.1 - 1.4 9.2 9.9 0.056 13.7 1.9 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) EphA2_TM PF14575.6 EGG24148.1 - 2.9 8.8 4.5 2.6 9.0 1.8 2.4 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Peroxin-3 PF04882.12 EGG24148.1 - 6.1 5.7 10.9 1 8.3 1.4 2.1 2 0 0 2 2 2 0 Peroxin-3 FAM76 PF16046.5 EGG24148.1 - 6.6 6.0 7.7 0.24 10.7 1.8 1.5 2 0 0 2 2 2 0 FAM76 protein TMEM208_SND2 PF05620.11 EGG24148.1 - 8.7 6.1 7.7 1.1 9.1 1.4 2.7 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Prefoldin PF02996.17 EGG24149.1 - 3.8e-19 68.8 4.1 5.5e-19 68.3 4.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF5113 PF17140.4 EGG24149.1 - 0.005 16.7 0.2 0.017 15.0 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF5113) Prefoldin_2 PF01920.20 EGG24149.1 - 0.011 15.7 3.6 0.093 12.7 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit CppA_C PF14507.6 EGG24149.1 - 0.038 14.7 0.9 0.092 13.5 0.9 1.6 1 0 0 1 1 1 0 CppA C-terminal Herpes_UL14 PF03580.14 EGG24149.1 - 0.089 13.0 0.6 3.7 7.8 0.0 2.2 1 1 1 2 2 2 0 Herpesvirus UL14-like protein Pro_sub2 PF18513.1 EGG24149.1 - 0.65 10.2 4.7 17 5.7 0.5 2.5 1 1 0 2 2 2 0 Prodomain subtilisin 2 GTP1_OBG PF01018.22 EGG24150.1 - 4.4e-41 140.0 11.5 1.9e-30 105.5 1.5 3.1 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.23 EGG24150.1 - 1.7e-19 69.9 0.0 7.4e-19 67.9 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG24150.1 - 3.2e-05 23.5 0.5 0.0015 18.1 0.0 3.1 3 0 0 3 3 3 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EGG24150.1 - 0.038 13.8 1.3 1.6 8.4 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EGG24150.1 - 1.2 9.6 4.3 8.7 6.9 0.0 3.3 3 0 0 3 3 3 0 ABC transporter RNase_PH PF01138.21 EGG24151.1 - 1.6e-21 77.2 0.3 3e-21 76.3 0.3 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGG24151.1 - 8.7e-05 22.5 0.0 0.00031 20.7 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 ABC_membrane PF00664.23 EGG24152.1 - 2.8e-72 243.6 34.9 1.9e-41 142.5 15.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGG24152.1 - 1.5e-46 158.3 0.0 2.7e-27 96.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGG24152.1 - 1.2e-09 37.9 5.1 0.024 14.1 0.1 4.3 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGG24152.1 - 3.7e-05 23.4 0.6 0.21 11.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG24152.1 - 6.1e-05 23.0 0.1 0.076 12.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGG24152.1 - 7e-05 23.1 0.6 0.21 11.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGG24152.1 - 0.00024 21.2 0.3 0.15 12.2 0.1 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGG24152.1 - 0.00031 21.2 0.1 1.5 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EGG24152.1 - 0.004 16.5 0.0 1.9 7.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_23 PF13476.6 EGG24152.1 - 0.024 15.2 4.9 2.2 8.7 0.1 2.9 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.6 EGG24152.1 - 0.024 14.4 2.8 1.7 8.4 0.3 3.2 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 EGG24152.1 - 0.025 13.8 0.1 8 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 EGG24152.1 - 0.027 14.5 2.1 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_7 PF12775.7 EGG24152.1 - 0.03 13.9 0.4 3.6 7.1 0.1 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EGG24152.1 - 0.036 13.8 0.6 2.5 7.8 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 EGG24152.1 - 0.061 12.5 0.2 5.8 6.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 EGG24152.1 - 0.069 12.9 0.8 1.8 8.3 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EGG24152.1 - 0.074 12.8 1.4 0.37 10.5 0.4 2.4 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 EGG24152.1 - 0.081 13.1 2.1 13 6.0 0.1 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 EGG24152.1 - 0.17 11.9 2.5 0.2 11.7 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 EGG24152.1 - 0.22 10.8 0.7 8.2 5.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 EGG24152.1 - 0.26 10.8 1.4 4.5 6.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 EGG24152.1 - 0.44 10.2 1.8 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Sulf_transp PF04143.14 EGG24152.1 - 1.7 8.1 9.0 0.049 13.2 1.4 2.2 2 1 1 3 3 3 0 Sulphur transport Pyr_redox_2 PF07992.14 EGG24153.1 - 1.2e-62 211.9 5.4 1.4e-62 211.6 5.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGG24153.1 - 4.5e-27 94.5 0.1 1.1e-26 93.3 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGG24153.1 - 8.5e-21 74.3 5.6 2.1e-15 57.0 0.5 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGG24153.1 - 3e-11 43.1 4.9 1.6e-09 37.3 1.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGG24153.1 - 1.5e-10 41.0 6.6 1.9e-09 37.4 0.1 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGG24153.1 - 6e-10 38.9 9.2 1.1e-05 24.8 0.9 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG24153.1 - 3.1e-09 36.9 2.2 7.7e-06 26.0 0.3 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGG24153.1 - 9.4e-07 28.2 1.0 9.4e-07 28.2 1.0 3.7 2 1 1 4 4 4 1 FAD binding domain HI0933_like PF03486.14 EGG24153.1 - 3e-06 26.2 9.2 1.9e-05 23.5 0.9 3.6 4 0 0 4 4 4 1 HI0933-like protein Thi4 PF01946.17 EGG24153.1 - 4.5e-06 26.1 4.0 0.00012 21.5 0.6 2.6 2 1 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 EGG24153.1 - 4.6e-06 26.1 0.5 0.019 14.3 0.0 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EGG24153.1 - 5.7e-05 22.5 12.1 0.00072 18.9 1.1 3.0 4 0 0 4 4 4 2 FAD binding domain K_oxygenase PF13434.6 EGG24153.1 - 0.00017 20.9 3.4 0.0044 16.2 0.1 2.8 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EGG24153.1 - 0.0016 18.1 20.6 0.022 14.3 1.9 4.1 3 2 1 5 5 5 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EGG24153.1 - 0.0031 16.9 0.4 0.7 9.2 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EGG24153.1 - 0.0073 16.7 1.5 0.27 11.7 0.1 3.1 2 2 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 EGG24153.1 - 0.013 14.3 0.1 0.013 14.3 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Mqo PF06039.15 EGG24153.1 - 0.047 12.3 0.7 0.09 11.3 0.2 1.7 1 1 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) XdhC_C PF13478.6 EGG24153.1 - 0.086 13.4 0.0 18 5.8 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain Amino_oxidase PF01593.24 EGG24153.1 - 0.15 11.3 0.5 6.9 5.8 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EGG24153.1 - 0.87 9.6 9.5 5.3 7.0 0.1 3.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EGG24153.1 - 3.2 6.7 8.6 0.74 8.8 0.4 3.3 4 1 1 5 5 5 0 Lycopene cyclase protein ELO PF01151.18 EGG24156.1 - 2.8e-61 207.2 31.2 3.3e-61 207.0 31.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family NAAA-beta PF15508.6 EGG24157.1 - 1.7e-11 44.2 0.0 3.1e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF4382 PF14321.6 EGG24157.1 - 0.024 14.9 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4382) NDUF_B12 PF08122.12 EGG24158.1 - 0.1 12.7 1.4 4.8 7.3 0.1 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Ank_2 PF12796.7 EGG24159.1 - 1.8e-36 124.6 24.8 1.5e-06 28.7 0.8 7.7 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24159.1 - 6.9e-36 122.2 25.6 7.4e-05 23.2 0.0 12.0 5 4 9 14 14 14 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24159.1 - 1.3e-27 95.5 28.3 0.1 13.0 0.0 15.3 3 2 13 16 16 16 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24159.1 - 8.7e-20 68.7 14.3 1.6 9.6 0.0 15.5 15 1 2 17 17 17 2 Ankyrin repeat DUF5049 PF16468.5 EGG24159.1 - 9.5e-10 38.2 2.7 3.4 7.6 0.0 9.2 5 2 4 9 9 9 1 Domain of unknown function (DUF5049) Ank PF00023.30 EGG24159.1 - 3.2e-05 24.2 12.2 51 4.6 0.0 10.4 9 3 0 9 9 9 0 Ankyrin repeat Exo_endo_phos PF03372.23 EGG24159.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Cys_knot PF00007.22 EGG24160.1 - 0.58 10.5 9.7 0.54 10.6 2.0 2.6 1 1 2 3 3 3 0 Cystine-knot domain FNIP PF05725.12 EGG24161.1 - 4.7e-06 26.7 17.0 0.05 13.8 0.1 7.2 6 1 1 7 7 7 4 FNIP Repeat F-box-like PF12937.7 EGG24161.1 - 0.11 12.4 3.0 0.082 12.8 0.5 2.1 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.7 EGG24162.1 - 0.0015 18.9 7.0 30 5.2 0.0 6.5 5 3 2 7 7 7 2 Leucine Rich repeats (2 copies) FNIP PF05725.12 EGG24162.1 - 0.0032 17.6 0.3 0.71 10.1 0.1 3.4 3 1 0 3 3 3 2 FNIP Repeat OrfB_Zn_ribbon PF07282.11 EGG24163.1 - 0.0015 18.5 0.0 0.0015 18.5 0.0 2.7 4 0 0 4 4 4 1 Putative transposase DNA-binding domain Rho_N PF07498.12 EGG24163.1 - 0.051 13.5 0.4 1.3 9.0 0.2 2.3 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain TFIIA PF03153.13 EGG24167.1 - 0.0038 17.3 23.7 0.0043 17.1 23.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EGG24167.1 - 0.0062 17.2 12.6 0.0099 16.6 12.6 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1548 PF07579.11 EGG24167.1 - 0.011 16.1 7.0 0.021 15.2 7.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) Band_3_cyto PF07565.13 EGG24167.1 - 0.04 13.7 6.6 0.051 13.4 6.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DcuC PF03606.15 EGG24167.1 - 0.062 11.8 0.7 0.09 11.2 0.7 1.3 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Ndc1_Nup PF09531.10 EGG24167.1 - 0.1 11.3 5.1 0.12 11.0 5.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Exonuc_VII_L PF02601.15 EGG24167.1 - 0.28 10.7 10.9 0.31 10.6 10.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SLC12 PF03522.15 EGG24167.1 - 0.28 10.2 14.0 0.4 9.7 14.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 EGG24167.1 - 0.47 9.6 2.7 0.49 9.6 2.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter OmpH PF03938.14 EGG24167.1 - 0.72 10.2 38.7 1.1 9.5 38.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Mit_KHE1 PF10173.9 EGG24167.1 - 0.9 9.6 11.3 27 4.8 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF5308 PF17233.2 EGG24167.1 - 1.2 9.3 8.1 0.09 13.0 3.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5308) LRR_4 PF12799.7 EGG24167.1 - 1.9 9.0 16.4 36 5.0 3.5 3.9 3 1 1 4 4 3 0 Leucine Rich repeats (2 copies) TERB2 PF15101.6 EGG24167.1 - 2 8.4 17.5 3.7 7.6 17.5 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Otopetrin PF03189.13 EGG24167.1 - 2.8 6.7 7.2 3.5 6.3 7.2 1.2 1 0 0 1 1 1 0 Otopetrin HCO3_cotransp PF00955.21 EGG24167.1 - 3.6 6.3 4.3 4.2 6.1 4.3 1.3 1 0 0 1 1 1 0 HCO3- transporter family DUF572 PF04502.13 EGG24167.1 - 3.7 7.1 20.7 5.8 6.4 20.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) RR_TM4-6 PF06459.12 EGG24167.1 - 4.5 7.0 20.4 6.4 6.5 20.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 EGG24167.1 - 5.1 5.8 15.8 8.3 5.1 15.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2072 PF09845.9 EGG24167.1 - 5.1 7.4 14.0 9.9 6.4 14.0 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Mgr1 PF08602.10 EGG24167.1 - 6.7 5.4 13.3 9.6 4.9 13.3 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit CDC45 PF02724.14 EGG24167.1 - 8.3 4.6 14.3 12 4.0 14.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.6 EGG24167.1 - 8.6 6.2 29.2 11 6.0 28.4 1.5 2 0 0 2 2 1 0 Spore coat protein CotO FNIP PF05725.12 EGG24168.1 - 4.7e-12 45.9 20.1 0.00029 20.9 0.0 6.3 3 1 1 6 6 6 6 FNIP Repeat Secretin_N_2 PF07655.13 EGG24168.1 - 0.22 12.1 12.6 0.36 11.4 12.6 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain FNIP PF05725.12 EGG24169.1 - 0.09 13.0 2.7 1.9 8.7 0.1 3.2 3 0 0 3 3 3 0 FNIP Repeat LRR_6 PF13516.6 EGG24170.1 - 2e-08 33.6 49.5 0.025 14.6 3.2 11.1 12 0 0 12 12 12 6 Leucine Rich repeat LRR_1 PF00560.33 EGG24170.1 - 0.00061 20.0 18.2 4.1 8.3 0.0 8.3 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_4 PF12799.7 EGG24170.1 - 0.031 14.7 40.7 0.075 13.5 3.1 7.7 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) p450 PF00067.22 EGG24172.1 - 1.2e-82 278.1 0.0 1.5e-82 277.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GST_C_3 PF14497.6 EGG24172.1 - 5.9e-11 42.4 1.7 1.4e-10 41.3 0.3 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG24172.1 - 2.2e-09 37.4 0.0 5.1e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG24172.1 - 1.2e-06 28.4 0.0 2.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGG24172.1 - 0.00044 20.6 0.0 0.034 14.5 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGG24172.1 - 0.019 15.3 0.0 0.11 12.8 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGG24172.1 - 0.023 15.0 0.0 0.29 11.5 0.0 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Mss4 PF04421.13 EGG24173.1 - 7.9 6.7 9.7 1.3 9.2 0.1 3.6 3 0 0 3 3 3 0 Mss4 protein DUF3439 PF11921.8 EGG24174.1 - 0.0043 17.0 13.3 0.0043 17.0 13.3 4.0 4 0 0 4 4 4 3 Domain of unknown function (DUF3439) Sld7_N PF18636.1 EGG24174.1 - 0.076 13.4 4.7 0.11 12.8 0.1 2.8 3 0 0 3 3 3 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain PFK PF00365.20 EGG24174.1 - 0.11 11.7 0.5 0.2 10.9 0.1 1.5 1 1 0 1 1 1 0 Phosphofructokinase Phage_lysozyme2 PF18013.1 EGG24176.1 - 0.012 15.6 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Phage tail lysozyme Prok-RING_4 PF14447.6 EGG24176.1 - 0.25 11.2 4.3 8.3 6.4 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 IBN_N PF03810.19 EGG24177.1 - 0.00022 21.0 0.1 0.00092 19.1 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Wzy_C PF04932.15 EGG24178.1 - 1.6e-05 24.6 5.4 7.3 6.2 0.0 5.0 5 0 0 5 5 5 4 O-Antigen ligase DUF3891 PF13030.6 EGG24178.1 - 0.00076 19.3 0.1 4 7.2 0.0 5.0 4 2 1 5 5 5 1 Protein of unknown function (DUF3891) CCDC-167 PF15188.6 EGG24178.1 - 0.002 18.4 7.6 1.1 9.7 0.1 4.9 4 0 0 4 4 4 1 Coiled-coil domain-containing protein 167 DUF4874 PF16173.5 EGG24178.1 - 0.0087 15.7 0.1 17 5.0 0.0 5.7 7 1 1 8 8 8 0 Domain of unknown function (DUF4874) CENP-H PF05837.12 EGG24178.1 - 0.012 16.0 0.0 69 3.9 0.0 4.4 3 1 1 4 4 4 0 Centromere protein H (CENP-H) MtrA PF04208.14 EGG24178.1 - 0.093 12.4 0.7 59 3.2 0.0 4.5 5 0 0 5 5 5 0 Tetrahydromethanopterin S-methyltransferase, subunit A DUF1689 PF07954.11 EGG24178.1 - 0.16 12.3 0.4 27 5.1 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1689) Pox_I6 PF04595.13 EGG24178.1 - 0.17 10.9 0.9 24 3.8 0.1 3.6 4 0 0 4 4 4 0 Poxvirus I6-like family PMT PF02366.18 EGG24178.1 - 0.23 11.0 0.9 1.5e+02 1.8 0.0 4.3 4 1 1 5 5 5 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2358 PF10184.9 EGG24178.1 - 0.24 11.7 0.5 54 4.1 0.0 4.2 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2358) DUF5518 PF17647.1 EGG24178.1 - 0.6 10.3 23.1 13 6.0 0.6 5.2 6 0 0 6 6 6 0 Family of unknown function (DUF5518) DivIC PF04977.15 EGG24178.1 - 7.3 6.4 7.1 28 4.6 0.1 4.0 4 0 0 4 4 4 0 Septum formation initiator Transgly_assoc PF04226.13 EGG24178.1 - 7.9 6.8 27.0 23 5.3 0.7 6.8 8 0 0 8 8 8 0 Transglycosylase associated protein IF4E PF01652.18 EGG24179.1 - 1.4e-25 89.9 1.1 8.2e-23 81.0 0.2 2.3 1 1 1 2 2 2 2 Eukaryotic initiation factor 4E DUF2407 PF10302.9 EGG24179.1 - 0.0074 16.8 0.3 0.014 15.9 0.3 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ank_2 PF12796.7 EGG24180.1 - 1.5e-34 118.4 22.8 2.4e-08 34.5 0.5 5.5 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG24180.1 - 6.1e-32 109.3 6.9 0.00059 20.1 0.0 10.7 3 1 8 11 11 11 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG24180.1 - 1.9e-27 95.2 10.0 3.7e-05 24.2 0.0 9.2 6 4 2 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24180.1 - 2.3e-16 58.2 5.5 2.1 9.2 0.0 11.4 12 1 1 13 13 13 3 Ankyrin repeat Ank PF00023.30 EGG24180.1 - 2.9e-07 30.6 5.9 2.1 8.9 0.0 6.7 4 2 2 6 6 6 2 Ankyrin repeat DUF5049 PF16468.5 EGG24180.1 - 1e-05 25.3 0.3 12 5.9 0.0 6.2 4 3 3 7 7 7 2 Domain of unknown function (DUF5049) RRM_1 PF00076.22 EGG24182.1 - 8.1e-25 86.4 0.6 4.3e-13 48.9 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGG24182.1 - 0.0016 18.3 0.1 0.44 10.5 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif TLV_coat PF00429.19 EGG24182.1 - 0.0039 15.9 0.5 0.0075 15.0 0.5 1.4 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) BRCT PF00533.26 EGG24182.1 - 0.088 13.2 0.0 0.34 11.3 0.0 2.1 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain HAT PF02184.16 EGG24182.1 - 0.38 10.8 4.2 38 4.4 0.0 4.4 4 0 0 4 4 4 0 HAT (Half-A-TPR) repeat WD40 PF00400.32 EGG24183.1 - 7.8e-38 127.8 34.0 7.7e-08 32.9 0.3 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG24183.1 - 2.8e-07 30.8 6.6 0.071 13.4 0.0 5.6 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGG24183.1 - 1e-06 28.3 0.1 5.5e-05 22.6 0.0 3.2 1 1 3 4 4 4 2 WD40-like domain F-box PF00646.33 EGG24183.1 - 2.3e-05 24.1 0.2 8e-05 22.4 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGG24183.1 - 0.0001 22.1 8.3 0.00023 21.0 0.3 3.1 2 1 1 3 3 3 1 F-box F-box-like PF12937.7 EGG24183.1 - 0.00013 21.8 0.1 0.00031 20.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.6 EGG24183.1 - 0.00032 20.4 0.4 0.0077 15.8 0.1 2.7 1 1 1 2 2 2 1 PQQ-like domain PBP1_TM PF14812.6 EGG24183.1 - 4.3 7.8 10.0 17 5.9 10.0 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.7 EGG24184.1 - 3.2e-26 91.7 9.1 8.3e-05 23.1 0.9 7.7 4 2 7 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24184.1 - 1.2e-18 67.2 8.9 0.0008 19.9 0.1 9.1 5 1 5 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24184.1 - 2.4e-13 50.0 6.5 0.021 15.1 0.1 9.1 7 2 2 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24184.1 - 8.6e-09 34.9 3.5 10 7.0 0.0 10.3 11 1 1 12 12 12 1 Ankyrin repeat RPW8 PF05659.11 EGG24184.1 - 0.035 13.8 0.2 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Ank PF00023.30 EGG24184.1 - 0.41 11.2 5.3 1.7e+02 2.9 0.0 6.6 7 2 1 8 8 8 0 Ankyrin repeat FNIP PF05725.12 EGG24185.1 - 3.9e-07 30.1 2.1 0.00014 22.0 0.2 2.3 2 0 0 2 2 2 2 FNIP Repeat FNIP PF05725.12 EGG24186.1 - 0.00065 19.8 11.0 3.5 7.9 0.0 7.2 7 0 0 7 7 7 1 FNIP Repeat CDC45 PF02724.14 EGG24186.1 - 0.053 11.8 7.3 0.027 12.8 5.3 1.4 2 0 0 2 2 2 0 CDC45-like protein TFB6 PF17110.5 EGG24186.1 - 0.086 12.6 2.6 0.17 11.6 2.6 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH F-box PF00646.33 EGG24186.1 - 0.1 12.5 0.5 0.33 10.9 0.5 2.0 1 0 0 1 1 1 0 F-box domain Chordopox_A13L PF05961.11 EGG24186.1 - 0.18 12.1 0.9 29 5.0 0.0 3.2 3 0 0 3 3 3 0 Chordopoxvirus A13L protein Cwf_Cwc_15 PF04889.12 EGG24186.1 - 0.29 10.9 10.3 0.66 9.7 10.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 EGG24186.1 - 0.32 10.1 12.5 0.51 9.4 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 EGG24186.1 - 0.76 9.0 13.0 1.2 8.3 13.0 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EGG24186.1 - 1 7.4 10.1 2.1 6.3 10.1 1.5 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EGG24186.1 - 1.4 8.2 6.8 2.6 7.4 6.8 1.3 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 EGG24186.1 - 3.7 8.0 13.9 11 6.4 13.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PPP4R2 PF09184.11 EGG24187.1 - 5.8e-16 58.9 8.6 5.8e-16 58.9 8.6 2.8 3 0 0 3 3 3 1 PPP4R2 DUF4919 PF16266.5 EGG24187.1 - 0.69 9.8 10.5 5 7.0 1.8 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4919) RNase_H2_suC PF08615.11 EGG24187.1 - 6.1 7.0 6.8 9.8 6.3 0.4 3.2 3 0 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PNK3P PF08645.11 EGG24188.1 - 1.6e-46 158.0 0.0 3e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EGG24188.1 - 4.5e-16 59.3 0.1 1.7e-13 51.0 0.0 2.9 2 1 0 2 2 1 1 AAA domain Histone PF00125.24 EGG24188.1 - 9.1e-13 48.7 8.5 0.00063 20.1 0.3 3.6 4 0 0 4 4 3 3 Core histone H2A/H2B/H3/H4 SDA1 PF05285.12 EGG24188.1 - 4.8e-05 22.9 15.0 7.2e-05 22.4 15.0 1.2 1 0 0 1 1 1 1 SDA1 Zeta_toxin PF06414.12 EGG24188.1 - 0.00014 21.3 0.0 0.14 11.4 0.0 2.4 1 1 1 2 2 2 2 Zeta toxin Nop14 PF04147.12 EGG24188.1 - 0.00023 19.5 20.2 0.00033 19.0 20.2 1.1 1 0 0 1 1 1 1 Nop14-like family 6PF2K PF01591.18 EGG24188.1 - 0.00028 20.2 0.0 0.18 11.1 0.0 2.5 2 0 0 2 2 2 2 6-phosphofructo-2-kinase KTI12 PF08433.10 EGG24188.1 - 0.00035 20.1 0.1 0.22 10.9 0.0 2.7 2 0 0 2 2 2 2 Chromatin associated protein KTI12 CDC45 PF02724.14 EGG24188.1 - 0.001 17.5 9.7 0.0013 17.1 9.7 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF913 PF06025.12 EGG24188.1 - 0.048 12.6 0.8 0.074 12.0 0.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CBFD_NFYB_HMF PF00808.23 EGG24188.1 - 0.068 13.5 8.7 6.2 7.2 0.0 3.9 4 0 0 4 4 4 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Zip PF02535.22 EGG24188.1 - 0.087 12.0 0.4 0.13 11.4 0.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Mpp10 PF04006.12 EGG24188.1 - 0.1 11.1 20.8 0.14 10.5 20.8 1.1 1 0 0 1 1 1 0 Mpp10 protein RRN3 PF05327.11 EGG24188.1 - 0.14 10.7 24.7 0.22 10.0 24.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Hydrolase_6 PF13344.6 EGG24188.1 - 0.14 12.3 0.1 4.7 7.4 0.0 3.0 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Sigma70_ner PF04546.13 EGG24188.1 - 0.27 11.1 18.6 0.64 9.9 18.6 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region SGT1 PF07093.11 EGG24188.1 - 0.35 9.2 14.2 0.54 8.6 14.2 1.2 1 0 0 1 1 1 0 SGT1 protein MIF4G_like_2 PF09090.11 EGG24188.1 - 0.64 9.5 6.7 1.3 8.5 6.7 1.4 1 0 0 1 1 1 0 MIF4G like RNA_pol_Rpc4 PF05132.14 EGG24188.1 - 2.3 8.6 4.0 4 7.8 4.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoIIIAH PF12685.7 EGG24188.1 - 2.4 7.9 12.8 4.7 7.0 12.8 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein YL1 PF05764.13 EGG24188.1 - 2.8 8.0 22.7 4.5 7.3 22.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Trypan_PARP PF05887.11 EGG24188.1 - 3.2 7.8 8.4 5.7 6.9 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TRAP_alpha PF03896.16 EGG24188.1 - 4.5 6.4 13.7 7.3 5.7 13.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 EGG24188.1 - 5.8 4.9 38.9 8.8 4.3 38.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi NPR3 PF03666.13 EGG24188.1 - 6.9 5.3 10.7 12 4.6 10.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 EGG24188.1 - 7.6 5.8 24.6 12 5.2 24.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tim54 PF11711.8 EGG24188.1 - 9.4 4.9 7.1 17 4.1 7.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Arylsulfotran_N PF17425.2 EGG24189.1 - 0.0011 18.9 1.0 0.0011 18.9 1.0 4.1 4 1 0 4 4 4 2 Arylsulfotransferase Ig-like domain fn3 PF00041.21 EGG24189.1 - 0.2 12.0 16.1 0.5 10.7 1.0 4.5 5 0 0 5 5 5 0 Fibronectin type III domain PNK3P PF08645.11 EGG24190.1 - 7.7e-46 155.7 0.0 1.6e-45 154.8 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EGG24190.1 - 2.1e-16 60.4 0.0 7.3e-14 52.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGG24190.1 - 2.7e-05 23.8 0.1 0.17 11.3 0.0 2.6 2 0 0 2 2 2 2 Chromatin associated protein KTI12 Nop14 PF04147.12 EGG24190.1 - 5.5e-05 21.6 9.7 7.6e-05 21.1 9.7 1.2 1 0 0 1 1 1 1 Nop14-like family Zeta_toxin PF06414.12 EGG24190.1 - 0.00011 21.6 0.0 0.17 11.1 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin Mpp10 PF04006.12 EGG24190.1 - 0.00083 17.9 14.2 0.001 17.6 14.2 1.1 1 0 0 1 1 1 1 Mpp10 protein Paf1 PF03985.13 EGG24190.1 - 0.0025 16.9 13.9 0.0037 16.3 13.9 1.2 1 0 0 1 1 1 1 Paf1 CDC45 PF02724.14 EGG24190.1 - 0.004 15.5 9.5 0.0052 15.1 9.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Presenilin PF01080.17 EGG24190.1 - 0.011 14.5 9.7 0.016 14.0 9.7 1.2 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 EGG24190.1 - 0.025 14.0 12.8 0.037 13.4 12.8 1.2 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 EGG24190.1 - 0.13 11.5 1.5 0.18 11.0 1.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 EGG24190.1 - 0.32 9.7 14.6 0.52 9.0 14.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CPSF100_C PF13299.6 EGG24190.1 - 0.42 10.8 5.8 0.9 9.7 5.8 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CAC1F_C PF16885.5 EGG24190.1 - 0.52 9.9 7.9 1 9.0 7.9 1.4 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Macoilin PF09726.9 EGG24190.1 - 3.5 6.1 11.7 4.9 5.6 11.7 1.1 1 0 0 1 1 1 0 Macoilin family SLC12 PF03522.15 EGG24190.1 - 4.2 6.3 15.0 6.8 5.6 15.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Merozoite_SPAM PF07133.11 EGG24190.1 - 4.4 7.3 46.3 9.3 6.2 46.3 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Connexin PF00029.19 EGG24190.1 - 4.8 6.9 5.0 9.8 5.9 5.0 1.5 1 0 0 1 1 1 0 Connexin LRR_4 PF12799.7 EGG24191.1 - 0.02 15.3 2.3 19 5.9 0.1 3.9 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) DDE_Tnp_4 PF13359.6 EGG24193.1 - 5.2e-05 23.0 0.1 8.6e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 EGG24193.1 - 0.0089 15.7 0.3 0.02 14.6 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease PAG PF15347.6 EGG24194.1 - 0.001 18.2 2.7 0.001 18.2 2.7 1.6 2 0 0 2 2 2 1 Phosphoprotein associated with glycosphingolipid-enriched CDC45 PF02724.14 EGG24194.1 - 0.0013 17.2 13.5 0.011 14.1 2.9 2.1 2 0 0 2 2 2 2 CDC45-like protein Mito_fiss_reg PF05308.11 EGG24194.1 - 2.5 8.1 7.2 0.18 11.9 0.5 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator SAPS PF04499.15 EGG24194.1 - 4.5 5.9 10.8 6.9 5.3 3.8 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 EGG24194.1 - 5 5.2 29.7 1.2 7.2 12.0 2.1 2 0 0 2 2 2 0 Nop14-like family AIF_C PF14721.6 EGG24194.1 - 6.9 7.0 11.8 0.26 11.6 0.5 2.6 2 1 1 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Rho_N PF07498.12 EGG24195.1 - 0.13 12.2 0.8 0.25 11.3 0.8 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Ribosomal_S13 PF00416.22 EGG24195.1 - 2.6 8.4 5.2 2.7 8.4 2.8 2.0 1 1 1 2 2 2 0 Ribosomal protein S13/S18 RRM_1 PF00076.22 EGG24196.1 - 1.4e-11 44.0 0.1 2e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EGG24197.1 - 3.7e-05 23.4 0.0 0.012 15.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S8 PF00082.22 EGG24198.1 - 4.3e-41 141.1 5.4 7.9e-41 140.3 5.4 1.4 1 0 0 1 1 1 1 Subtilase family Insulin_TMD PF17870.1 EGG24198.1 - 0.061 13.4 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF1065 PF06358.11 EGG24198.1 - 0.33 10.9 2.2 1.5 8.8 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1065) Stealth_CR2 PF11380.8 EGG24200.1 - 1.9e-46 156.7 0.6 1.7e-45 153.7 0.1 2.4 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 EGG24200.1 - 3.8e-20 71.5 3.9 1e-19 70.1 3.9 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 EGG24200.1 - 5.1e-20 71.1 0.5 1.8e-19 69.3 0.5 2.1 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Notch PF00066.17 EGG24200.1 - 8e-14 51.8 35.2 4.2e-07 30.3 15.1 2.6 2 0 0 2 2 2 2 LNR domain Stealth_CR1 PF17101.5 EGG24200.1 - 3.4e-10 39.5 0.0 7.7e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 EF-hand_1 PF00036.32 EGG24200.1 - 0.025 14.1 0.3 0.15 11.7 0.2 2.3 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 EGG24200.1 - 0.035 13.6 0.6 0.11 12.0 0.6 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EGG24200.1 - 0.052 13.5 0.3 0.4 10.7 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain Macoilin PF09726.9 EGG24200.1 - 2.3 6.7 11.1 3.9 5.9 11.1 1.3 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 EGG24203.1 - 9.7e-36 123.5 0.1 9.7e-36 123.5 0.1 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG24203.1 - 1.2e-25 90.3 0.2 5.4e-25 88.1 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase HECT PF00632.25 EGG24203.1 - 1.2e-22 80.8 0.6 4.2e-22 79.0 0.6 1.9 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Kdo PF06293.14 EGG24203.1 - 0.00077 18.9 0.1 0.0093 15.3 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG24203.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FYDLN_acid PF09538.10 EGG24203.1 - 0.12 13.1 6.8 0.72 10.6 6.8 2.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) GST_N PF02798.20 EGG24204.1 - 1.2e-11 44.8 0.0 1.8e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGG24204.1 - 9.9e-11 41.9 0.0 1.7e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGG24204.1 - 3.2e-08 33.7 0.0 1.3e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG24204.1 - 9.5e-08 32.2 0.1 1.8e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGG24204.1 - 3.3e-06 27.3 0.0 6.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGG24204.1 - 3.2e-05 23.9 0.0 6.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EGG24204.1 - 0.075 13.3 0.0 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 Glutaredoxin GST_C_6 PF17171.4 EGG24204.1 - 0.11 12.3 0.1 0.27 11.1 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG24206.1 - 2.4e-09 37.3 0.0 3.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG24206.1 - 3.1e-09 36.7 0.0 5.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGG24206.1 - 7.3e-08 32.5 0.0 1.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGG24206.1 - 9e-07 29.2 0.2 0.00066 20.0 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGG24206.1 - 2.3e-05 24.6 0.0 8.7e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EGG24206.1 - 0.00065 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGG24206.1 - 0.037 14.3 0.0 0.079 13.3 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain efThoc1 PF11957.8 EGG24207.1 - 5.7e-67 226.5 37.9 2.4e-62 211.2 30.9 3.4 1 1 1 2 2 2 2 THO complex subunit 1 transcription elongation factor BUD22 PF09073.10 EGG24207.1 - 0.00039 19.9 20.2 0.00064 19.2 20.2 1.3 1 0 0 1 1 1 1 BUD22 DUF4407 PF14362.6 EGG24207.1 - 0.21 10.9 3.9 0.42 9.9 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2894 PF11445.8 EGG24207.1 - 0.31 11.5 6.8 0.67 10.4 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) RNA_pol_3_Rpc31 PF11705.8 EGG24207.1 - 4.5 7.5 20.5 0.51 10.6 15.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF812 PF05667.11 EGG24208.1 - 8.4e-135 451.0 4.8 2.9e-119 399.7 1.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF812) ANAPC4 PF12896.7 EGG24208.1 - 0.18 11.3 5.8 1 8.8 0.1 3.5 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 4 EST1 PF10374.9 EGG24208.1 - 5.8 7.5 9.7 59 4.3 5.8 3.3 3 1 0 3 3 3 0 Telomerase activating protein Est1 ubiquitin PF00240.23 EGG24209.1 - 1.5e-06 27.9 0.2 2e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGG24209.1 - 0.00014 22.2 0.2 0.00018 21.9 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGG24209.1 - 0.006 16.5 0.0 0.0071 16.3 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ank_2 PF12796.7 EGG24210.1 - 1.1e-53 179.8 19.8 9.7e-11 42.1 0.1 7.2 3 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24210.1 - 2.3e-43 146.0 10.2 4.4e-05 23.9 0.0 10.4 7 3 5 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24210.1 - 2.5e-42 142.3 17.0 0.0017 18.6 0.1 14.9 3 3 13 16 16 16 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24210.1 - 6.8e-24 81.4 8.5 2 9.2 0.0 14.6 15 1 1 16 16 16 5 Ankyrin repeat DUF5049 PF16468.5 EGG24210.1 - 2.6e-15 56.0 7.5 1.6 8.7 0.0 12.8 7 2 7 14 14 14 3 Domain of unknown function (DUF5049) Ank PF00023.30 EGG24210.1 - 2.7e-08 33.9 9.4 16 6.2 0.0 11.2 7 4 4 11 11 11 1 Ankyrin repeat CNOT1_HEAT PF16418.5 EGG24210.1 - 0.088 12.9 0.0 55 3.8 0.0 4.1 4 2 0 4 4 4 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Rieske PF00355.26 EGG24210.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain EGF_2 PF07974.13 EGG24211.1 - 8.3e-06 26.1 11.3 2.2e-05 24.7 11.3 1.7 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 EGG24211.1 - 0.0016 18.7 4.1 0.0048 17.2 4.1 1.8 1 0 0 1 1 1 1 EB module LRR_8 PF13855.6 EGG24211.1 - 0.0018 18.0 6.7 0.037 13.8 1.2 3.2 2 1 0 2 2 2 2 Leucine rich repeat DUF3844 PF12955.7 EGG24211.1 - 0.0042 17.2 2.5 0.0058 16.7 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) hEGF PF12661.7 EGG24211.1 - 0.005 17.4 11.1 0.005 17.4 11.1 2.3 2 0 0 2 2 2 1 Human growth factor-like EGF I-EGF_1 PF18372.1 EGG24211.1 - 0.016 15.3 10.8 0.047 13.8 10.8 1.8 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 LRR_9 PF14580.6 EGG24211.1 - 0.02 14.4 1.9 0.072 12.6 1.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeat Insulin_TMD PF17870.1 EGG24211.1 - 0.029 14.4 0.1 0.077 13.1 0.1 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EGF_Tenascin PF18720.1 EGG24211.1 - 0.22 11.6 4.3 0.68 10.1 4.3 1.8 1 0 0 1 1 1 0 Tenascin EGF domain EGF PF00008.27 EGG24211.1 - 0.25 11.7 11.4 0.28 11.5 9.8 2.0 2 0 0 2 2 2 0 EGF-like domain VID27 PF08553.10 EGG24212.1 - 1.3e-95 320.4 5.6 6.9e-95 318.1 5.6 1.9 1 1 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EGG24212.1 - 1.8e-11 44.2 0.1 1.8e-11 44.2 0.1 6.1 4 2 1 5 5 5 1 VID27 N-terminal region VID27_PH PF17747.1 EGG24212.1 - 1.1e-08 35.3 8.4 3.9e-08 33.6 5.1 2.7 2 0 0 2 2 2 1 VID27 PH-like domain CLTH PF10607.9 EGG24215.1 - 1.6e-35 122.2 3.1 1.6e-35 122.2 3.1 2.2 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain GrpE PF01025.19 EGG24215.1 - 0.0014 18.3 7.5 0.023 14.4 8.4 2.3 2 0 0 2 2 2 1 GrpE FapA PF03961.13 EGG24215.1 - 0.0031 16.2 3.9 0.0031 16.2 3.9 1.8 2 0 0 2 2 2 1 Flagellar Assembly Protein A zf-RING_UBOX PF13445.6 EGG24215.1 - 0.0047 16.9 0.2 0.22 11.5 0.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger Mitofilin PF09731.9 EGG24215.1 - 0.0056 15.6 6.4 0.0083 15.0 6.4 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Hrs_helical PF12210.8 EGG24215.1 - 0.017 15.7 6.0 0.043 14.4 6.0 1.7 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Polbeta PF18765.1 EGG24215.1 - 0.059 13.4 0.1 0.22 11.7 0.1 2.0 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase LisH PF08513.11 EGG24215.1 - 0.076 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 LisH NTP_transf_2 PF01909.23 EGG24215.1 - 0.11 12.8 0.0 0.43 10.9 0.0 2.0 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF4113 PF13438.6 EGG24215.1 - 0.13 12.3 0.0 0.5 10.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) TPR_MLP1_2 PF07926.12 EGG24215.1 - 0.24 11.4 8.2 2.3 8.3 8.0 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein IpaC_SipC PF09599.10 EGG24215.1 - 0.26 10.8 4.8 0.32 10.5 3.6 1.6 1 1 1 2 2 2 0 Salmonella-Shigella invasin protein C (IpaC_SipC) zf-H2C2_2 PF13465.6 EGG24215.1 - 0.37 11.3 1.5 1.2 9.6 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DUF4407 PF14362.6 EGG24215.1 - 0.47 9.8 4.4 0.13 11.6 1.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EGG24215.1 - 0.48 10.8 5.9 1.6 9.1 5.4 2.2 3 0 0 3 3 2 0 Outer membrane protein (OmpH-like) DASH_Dad1 PF08649.10 EGG24215.1 - 0.63 10.3 7.2 0.12 12.6 1.1 2.7 2 1 1 3 3 2 0 DASH complex subunit Dad1 DUF4175 PF13779.6 EGG24215.1 - 0.63 7.9 6.2 1.1 7.1 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ApoO PF09769.9 EGG24215.1 - 0.77 9.7 2.2 5.9 6.9 0.5 2.7 2 1 0 2 2 2 0 Apolipoprotein O Snapin_Pallidin PF14712.6 EGG24215.1 - 1.2 9.6 8.3 4.2 7.9 8.3 2.0 1 0 0 1 1 1 0 Snapin/Pallidin CLZ PF16526.5 EGG24215.1 - 1.4 9.3 10.0 0.63 10.4 4.5 2.7 2 1 1 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 EGG24215.1 - 5.9 6.9 9.6 1.1 9.4 2.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) COG2 PF06148.11 EGG24215.1 - 8.2 6.5 8.6 22 5.2 5.1 2.7 2 2 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 RabGAP-TBC PF00566.18 EGG24216.1 - 2.7e-37 128.5 0.3 3.8e-37 128.0 0.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain YbgS PF13985.6 EGG24216.1 - 1.3 9.3 3.8 2.2 8.6 3.8 1.2 1 0 0 1 1 1 0 YbgS-like protein DEAD PF00270.29 EGG24217.1 - 2.4e-24 86.1 1.1 2.7e-23 82.6 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG24217.1 - 3.2e-06 27.4 0.1 1e-05 25.8 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GTP_EFTU PF00009.27 EGG24218.1 - 2.4e-49 167.5 0.0 3.6e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGG24218.1 - 5e-05 22.8 0.4 0.0019 17.7 0.0 2.2 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGG24218.1 - 0.00039 20.2 0.9 0.0034 17.1 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 EGG24218.1 - 0.0012 18.4 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGG24218.1 - 0.0045 17.1 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGG24218.1 - 0.081 13.2 0.1 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase LepA_C PF06421.12 EGG24219.1 - 7.8e-47 157.9 1.9 1.1e-46 157.4 1.9 1.2 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EGG24219.1 - 8e-19 67.5 0.0 1.4e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 EGG24219.1 - 0.0036 17.1 0.2 0.25 11.2 0.0 2.3 2 0 0 2 2 2 2 Class II release factor RF3, C-terminal domain zf-C3HC4 PF00097.25 EGG24220.1 - 0.0015 18.4 2.8 0.0015 18.4 2.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG24220.1 - 0.0059 16.5 8.9 0.011 15.7 8.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGG24220.1 - 0.02 14.7 8.4 0.043 13.7 8.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG24220.1 - 0.038 14.0 6.6 0.048 13.7 5.5 1.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 EGG24220.1 - 0.056 13.8 9.0 0.15 12.4 9.0 1.7 1 0 0 1 1 1 0 Ring finger domain PSI_integrin PF17205.3 EGG24220.1 - 2 8.2 7.6 0.089 12.6 1.8 1.7 2 0 0 2 2 2 0 Integrin plexin domain Esterase_phd PF10503.9 EGG24221.1 - 1.2e-05 24.9 0.9 2.2e-05 24.1 0.1 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase PHD_Oberon PF07227.11 EGG24221.1 - 0.061 13.2 4.1 0.14 12.0 4.1 1.6 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein zf-B_box PF00643.24 EGG24221.1 - 0.21 11.7 5.3 0.51 10.5 5.3 1.6 1 0 0 1 1 1 0 B-box zinc finger AAA_16 PF13191.6 EGG24222.1 - 0.001 19.5 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EGG24222.1 - 0.0028 18.2 2.0 0.0073 16.8 0.0 2.5 2 1 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 EGG24222.1 - 0.0069 16.6 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain zf-C3HC4 PF00097.25 EGG24222.1 - 0.022 14.6 2.3 0.078 12.9 2.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MMR_HSR1 PF01926.23 EGG24222.1 - 0.029 14.5 0.0 0.065 13.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-C3HC4_3 PF13920.6 EGG24222.1 - 0.032 14.1 5.7 0.064 13.1 5.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RsgA_GTPase PF03193.16 EGG24222.1 - 0.037 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase zf-C3HC4_4 PF15227.6 EGG24222.1 - 0.041 14.0 2.5 0.14 12.3 2.5 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGG24222.1 - 0.045 13.7 7.9 0.11 12.4 7.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain AAA_29 PF13555.6 EGG24222.1 - 0.056 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-RING_UBOX PF13445.6 EGG24222.1 - 0.35 10.9 6.9 1 9.5 6.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGG24222.1 - 1.7 8.6 6.8 4.1 7.3 6.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Adaptin_N PF01602.20 EGG24223.1 - 6.6e-124 414.3 5.2 9.5e-124 413.8 5.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGG24223.1 - 4e-10 40.0 1.5 3.6e-08 33.6 0.2 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGG24223.1 - 0.0037 17.4 4.0 5.1 7.6 0.0 4.4 5 0 0 5 5 5 2 HEAT repeat RTP1_C1 PF10363.9 EGG24223.1 - 0.0057 16.8 0.1 2.7 8.2 0.0 3.4 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 AP4E_app_platf PF14807.6 EGG24223.1 - 0.024 15.0 0.4 0.068 13.5 0.4 1.8 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Alpha_adaptinC2 PF02883.20 EGG24223.1 - 0.025 14.9 0.7 0.051 13.9 0.7 1.5 1 0 0 1 1 1 0 Adaptin C-terminal domain AP3D1 PF06375.11 EGG24223.1 - 0.059 13.6 7.4 2.4 8.4 0.0 3.3 1 1 2 3 3 3 0 AP-3 complex subunit delta-1 cNMP_binding PF00027.29 EGG24224.1 - 1.5e-42 143.6 0.0 1.3e-21 76.5 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 7TMR-HDED PF07697.11 EGG24224.1 - 0.0038 17.4 4.6 0.66 10.1 0.0 2.7 3 0 0 3 3 3 2 7TM-HD extracellular EF-hand_7 PF13499.6 EGG24225.1 - 1.8e-09 37.9 4.6 8.1e-07 29.4 0.9 3.6 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EGG24225.1 - 3e-07 29.6 0.4 0.0047 16.4 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGG24225.1 - 1.9e-06 27.4 10.0 0.0062 16.4 0.2 5.1 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 EGG24225.1 - 5.1e-05 22.5 11.4 0.022 14.3 0.2 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EGG24225.1 - 0.0029 17.4 1.2 1.2 9.0 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair Imm40 PF15569.6 EGG24225.1 - 0.028 14.5 1.0 4.7 7.4 0.1 2.9 2 0 0 2 2 2 0 Immunity protein 40 RVT_1 PF00078.27 EGG24226.1 - 0.0023 17.5 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SR-25 PF10500.9 EGG24228.1 - 0.00026 20.7 7.9 0.00029 20.5 7.9 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 EGG24228.1 - 0.039 13.7 1.7 0.046 13.4 1.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 LRR_1 PF00560.33 EGG24229.1 - 0.28 11.9 5.2 25 6.0 0.1 5.5 4 1 1 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 EGG24229.1 - 0.61 10.6 12.3 8.7 6.9 0.3 4.7 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGG24229.1 - 6.4 7.1 12.4 1.3 9.3 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich repeat VDE PF07137.11 EGG24233.1 - 0.036 13.6 0.7 0.045 13.3 0.7 1.1 1 0 0 1 1 1 0 VDE lipocalin domain Ku PF02735.16 EGG24234.1 - 1.3e-42 145.8 0.1 5.3e-42 143.8 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 EGG24234.1 - 2.3e-39 134.3 1.6 5.9e-39 132.9 1.6 1.8 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 EGG24234.1 - 1.2e-20 74.3 4.7 2.5e-20 73.2 4.7 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EGG24234.1 - 9.5e-12 45.5 0.5 7.5e-11 42.6 0.2 2.8 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SBP_bac_5 PF00496.22 EGG24234.1 - 0.053 12.5 0.1 0.097 11.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle VWA PF00092.28 EGG24234.1 - 0.092 13.0 1.2 0.26 11.5 1.0 1.8 1 1 1 2 2 2 0 von Willebrand factor type A domain Aminotran_3 PF00202.21 EGG24235.1 - 5.6e-113 377.7 0.0 6.9e-113 377.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_5 PF00266.19 EGG24235.1 - 0.0086 15.1 0.0 0.021 13.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGG24235.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Lactamase_B_4 PF13691.6 EGG24235.1 - 0.16 11.6 0.0 0.63 9.8 0.0 2.0 2 0 0 2 2 2 0 tRNase Z endonuclease Coiled PF05710.12 EGG24236.1 - 6.5e-13 49.3 16.9 8.5e-13 48.9 16.9 1.1 1 0 0 1 1 1 1 Coiled coil Myosin_head PF00063.21 EGG24237.1 - 4.3e-253 841.5 1.0 4.3e-253 841.5 1.0 3.6 4 1 1 5 5 5 1 Myosin head (motor domain) DIL PF01843.19 EGG24237.1 - 2.1e-16 60.1 0.0 2.1e-16 60.1 0.0 4.6 4 1 0 4 4 4 1 DIL domain IQ PF00612.27 EGG24237.1 - 1.7e-14 52.2 27.2 0.0018 17.9 0.9 6.8 6 0 0 6 6 6 6 IQ calmodulin-binding motif Myosin_N PF02736.19 EGG24237.1 - 0.0083 15.9 3.1 0.024 14.5 3.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Rbsn PF11464.8 EGG24237.1 - 0.08 12.7 6.6 6.7 6.5 0.3 4.3 3 0 0 3 3 3 0 Rabenosyn Rab binding domain Shugoshin_N PF07558.11 EGG24237.1 - 0.084 12.8 14.3 0.27 11.1 0.1 5.0 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region AAA_16 PF13191.6 EGG24237.1 - 0.12 12.7 0.0 0.12 12.7 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 EGG24237.1 - 0.51 10.6 0.0 0.51 10.6 0.0 3.8 3 0 0 3 3 3 0 AAA domain Metallophos PF00149.28 EGG24238.1 - 3.1e-39 135.6 0.3 4.3e-39 135.1 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGG24238.1 - 5.8e-05 23.4 0.5 0.00013 22.3 0.5 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EGG24238.1 - 0.043 14.0 0.0 0.067 13.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain GMC_oxred_N PF00732.19 EGG24239.1 - 5.8e-31 108.0 0.0 8.1e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGG24239.1 - 3.8e-27 95.6 0.0 6.1e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase HNH_3 PF13392.6 EGG24240.1 - 0.00028 20.6 0.0 0.00058 19.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease zf-His_Me_endon PF05551.11 EGG24240.1 - 0.00044 20.5 0.1 0.00044 20.5 0.1 2.1 2 1 0 2 2 2 1 Zinc-binding loop region of homing endonuclease S-antigen PF05756.11 EGG24240.1 - 0.037 14.4 0.0 0.037 14.4 0.0 1.9 2 1 0 2 2 2 0 S-antigen protein GMC_oxred_N PF00732.19 EGG24241.1 - 1.1e-31 110.3 0.0 4.1e-31 108.5 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGG24241.1 - 3.1e-28 99.1 0.0 5.4e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EGG24241.1 - 0.022 13.8 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 EGG24241.1 - 0.12 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CactinC_cactus PF09732.9 EGG24242.1 - 1.4e-59 199.5 7.3 3e-59 198.4 7.3 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 EGG24242.1 - 2.4e-46 158.0 0.1 2.4e-46 158.0 0.1 3.2 3 1 0 3 3 3 1 Conserved mid region of cactin F-box-like PF12937.7 EGG24248.1 - 0.00066 19.5 0.0 0.0021 17.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 EGG24248.1 - 0.022 14.3 0.1 0.089 12.4 0.0 2.1 2 0 0 2 2 2 0 F-box OSK PF17182.4 EGG24248.1 - 0.024 13.9 0.2 0.072 12.3 0.2 1.8 1 0 0 1 1 1 0 OSK domain IMUP PF15761.5 EGG24248.1 - 5.2 7.8 8.6 8.1 7.2 8.6 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF5305 PF17231.2 EGG24249.1 - 0.00072 19.0 0.4 0.0017 17.8 0.4 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5305) DUF2615 PF11027.8 EGG24249.1 - 0.0028 17.7 0.2 0.0054 16.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) TMEM154 PF15102.6 EGG24249.1 - 0.0038 17.1 2.7 0.0084 16.0 2.7 1.5 1 0 0 1 1 1 1 TMEM154 protein family TMEM51 PF15345.6 EGG24249.1 - 0.0039 17.1 1.7 0.0057 16.5 1.7 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 TMEM223 PF14640.6 EGG24249.1 - 0.07 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 223 Orf78 PF06024.12 EGG24249.1 - 1.1 9.6 7.9 0.12 12.7 1.9 2.3 2 0 0 2 2 2 0 Orf78 (ac78) DUF5305 PF17231.2 EGG24250.1 - 6.7e-05 22.4 3.3 6.7e-05 22.4 3.3 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5305) TMEM51 PF15345.6 EGG24250.1 - 0.0015 18.4 1.5 0.0025 17.7 1.5 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 DUF2970 PF11174.8 EGG24250.1 - 0.031 14.1 0.0 0.031 14.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) TMEM223 PF14640.6 EGG24250.1 - 0.063 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 223 KRE9 PF05390.11 EGG24250.1 - 0.11 13.2 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 DUF1676 PF07898.13 EGG24250.1 - 0.14 12.2 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF872 PF05915.12 EGG24250.1 - 2.7 8.2 4.7 0.62 10.2 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Peptidase_M56 PF05569.11 EGG24250.1 - 2.8 7.1 7.1 0.13 11.5 1.4 1.6 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF2615 PF11027.8 EGG24250.1 - 3.8 7.7 5.3 0.34 11.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Orf78 PF06024.12 EGG24251.1 - 1.5e-05 25.2 2.8 0.12 12.7 0.1 2.5 2 0 0 2 2 2 2 Orf78 (ac78) DUF5305 PF17231.2 EGG24251.1 - 4e-05 23.1 3.0 0.00077 18.9 0.4 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5305) RIFIN PF02009.16 EGG24251.1 - 0.00026 21.0 9.0 0.018 14.9 0.3 2.2 2 0 0 2 2 2 2 Rifin TMEM154 PF15102.6 EGG24251.1 - 0.0014 18.5 9.6 0.024 14.6 1.6 2.3 2 0 0 2 2 2 2 TMEM154 protein family TMEM51 PF15345.6 EGG24251.1 - 0.0018 18.2 1.3 0.032 14.1 0.3 2.2 2 0 0 2 2 2 1 Transmembrane protein 51 TNFR_16_TM PF18422.1 EGG24251.1 - 0.0061 16.5 4.5 0.79 9.7 0.1 2.6 2 0 0 2 2 2 2 Tumor necrosis factor receptor member 16 trans-membrane domain DUF4366 PF14283.6 EGG24251.1 - 0.02 14.9 0.2 0.96 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF4064 PF13273.6 EGG24251.1 - 0.021 15.1 0.6 0.54 10.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) LRRC37AB_C PF14914.6 EGG24251.1 - 0.12 12.3 6.9 0.12 12.2 1.0 2.8 3 0 0 3 3 3 0 LRRC37A/B like protein 1 C-terminal domain SARAF PF06682.12 EGG24251.1 - 0.13 11.8 0.7 14 5.2 0.1 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF5383 PF17355.2 EGG24251.1 - 2.7 8.4 9.8 2.6 8.4 0.1 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5383) SR-25 PF10500.9 EGG24252.1 - 8.9 5.9 20.4 13 5.3 20.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HEAT PF02985.22 EGG24253.1 - 1.4e-06 28.0 1.3 0.14 12.5 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat Uso1_p115_C PF04871.13 EGG24253.1 - 0.001 19.5 2.8 0.001 19.5 2.8 4.1 4 1 0 4 4 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Cnd1 PF12717.7 EGG24253.1 - 0.034 14.2 10.4 0.22 11.6 0.4 3.6 4 0 0 4 4 3 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGG24253.1 - 0.036 14.7 0.0 5 7.8 0.0 3.1 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGG24253.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.7 3 0 0 3 3 3 0 CLASP N terminal LisH PF08513.11 EGG24253.1 - 0.2 11.7 4.4 1.5 8.9 0.1 2.8 3 0 0 3 3 3 0 LisH EGF_2 PF07974.13 EGG24253.1 - 0.66 10.4 15.0 1.6 9.2 15.0 1.6 1 0 0 1 1 1 0 EGF-like domain APG6_N PF17675.1 EGG24253.1 - 1.2 9.6 12.0 0.28 11.7 0.5 2.8 2 0 0 2 2 2 0 Apg6 coiled-coil region PKcGMP_CC PF16808.5 EGG24253.1 - 4.5 7.2 8.8 11 6.0 8.8 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase EGF_Tenascin PF18720.1 EGG24253.1 - 5.3 7.2 5.7 12 6.0 5.7 1.6 1 0 0 1 1 1 0 Tenascin EGF domain UPF0228 PF05727.11 EGG24253.1 - 6.9 6.5 8.4 17 5.3 0.3 4.5 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0228) HIP1_clath_bdg PF16515.5 EGG24253.1 - 8.3 7.1 17.4 1.5 9.4 1.1 4.0 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ank_2 PF12796.7 EGG24254.1 - 5.9e-08 33.2 0.0 0.0025 18.3 0.0 4.0 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG24254.1 - 0.00081 19.7 0.0 53 4.9 0.0 6.1 8 0 0 8 8 8 0 Ankyrin repeat Apc15p PF05841.11 EGG24254.1 - 0.081 13.7 5.9 0.2 12.5 5.9 1.7 1 0 0 1 1 1 0 Apc15p protein EST1 PF10374.9 EGG24254.1 - 8.1 7.1 11.1 9.1 6.9 2.9 3.4 3 1 1 4 4 4 0 Telomerase activating protein Est1 OHCU_decarbox PF09349.10 EGG24255.1 - 9.6e-39 133.4 0.0 1.3e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 OHCU decarboxylase Amidohydro_1 PF01979.20 EGG24255.1 - 1.5e-07 31.1 0.3 6.9e-07 28.9 0.3 1.9 1 1 1 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGG24255.1 - 9.7e-07 28.6 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Swi5 PF07061.11 EGG24255.1 - 0.098 12.8 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Swi5 LRR_6 PF13516.6 EGG24256.1 - 0.23 11.6 4.2 2.2 8.6 0.2 3.7 3 0 0 3 3 3 0 Leucine Rich repeat Ank_2 PF12796.7 EGG24257.1 - 3.8e-14 53.0 7.5 1e-05 26.0 0.1 7.3 6 2 2 8 8 8 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG24257.1 - 3.6e-08 33.1 3.7 78 4.4 0.0 10.9 10 0 0 10 10 10 0 Ankyrin repeat Ank_4 PF13637.6 EGG24257.1 - 1e-07 32.3 13.4 0.095 13.3 0.1 10.1 12 1 1 13 13 13 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24257.1 - 0.00051 20.3 0.5 65 4.0 0.0 6.5 5 2 2 7 7 7 0 Ankyrin repeats (many copies) DUF249 PF03158.13 EGG24257.1 - 0.14 11.8 14.6 4.3 7.0 0.1 6.1 5 1 0 6 6 6 0 Multigene family 530 protein HGAL PF15666.5 EGG24258.1 - 0.087 12.9 0.4 0.099 12.8 0.4 1.3 1 1 0 1 1 1 0 Germinal center-associated lymphoma FTH PF01827.27 EGG24259.1 - 0.34 10.7 5.0 0.16 11.8 0.2 2.7 3 0 0 3 3 3 0 FTH domain LRR_6 PF13516.6 EGG24259.1 - 3.2 8.1 11.2 4.3 7.6 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeat Metallophos PF00149.28 EGG24260.1 - 1.2e-18 68.4 0.7 1.2e-18 68.4 0.7 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EGG24260.1 - 1.3e-18 67.3 5.4 3.3e-18 66.0 5.4 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 EGG24260.1 - 0.00032 21.5 0.0 0.0014 19.5 0.0 2.2 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 EGG24260.1 - 0.00075 19.7 0.0 0.0036 17.5 0.0 2.1 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF2369 PF10179.9 EGG24260.1 - 0.14 12.5 1.1 10 6.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) DNA_pol_phi PF04931.13 EGG24260.1 - 1.1 7.3 9.3 1.7 6.7 9.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4637 PF15470.6 EGG24260.1 - 4.7 6.9 5.9 7.5 6.3 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) ABC_membrane PF00664.23 EGG24262.1 - 5.3e-70 236.2 30.9 1.4e-40 139.7 14.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGG24262.1 - 1.4e-47 161.7 0.0 4e-27 95.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGG24262.1 - 1.3e-10 41.1 3.0 0.012 15.0 0.0 4.3 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGG24262.1 - 1.6e-06 27.8 0.8 0.1 12.3 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG24262.1 - 2.1e-05 24.5 0.2 0.021 14.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGG24262.1 - 0.00011 22.5 0.2 0.65 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGG24262.1 - 0.00019 21.5 0.5 0.16 12.0 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGG24262.1 - 0.0006 20.4 0.1 1.2 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGG24262.1 - 0.00071 20.0 0.5 1.7 9.0 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EGG24262.1 - 0.00091 19.1 1.4 2 8.2 0.2 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 EGG24262.1 - 0.0077 15.4 0.1 3.1 6.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EGG24262.1 - 0.01 15.1 0.0 0.45 9.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 EGG24262.1 - 0.013 15.6 2.6 0.55 10.3 0.1 2.6 2 0 0 2 2 2 0 Dynamin family AAA PF00004.29 EGG24262.1 - 0.018 15.4 0.6 12 6.3 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EGG24262.1 - 0.028 14.2 0.5 0.75 9.5 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EGG24262.1 - 0.034 13.9 0.4 2.1 8.1 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EGG24262.1 - 0.066 12.7 0.2 5.2 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 EGG24262.1 - 0.072 12.3 0.1 4.7 6.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 EGG24262.1 - 0.12 11.7 0.4 9.6 5.5 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 EGG24262.1 - 0.14 12.2 2.3 0.22 11.6 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain Roc PF08477.13 EGG24262.1 - 0.15 12.3 2.4 14 5.9 0.1 3.6 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EGG24262.1 - 0.17 12.5 0.1 33 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGG24262.1 - 0.25 10.9 1.0 6.1 6.4 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HypA PF01155.19 EGG24264.1 - 0.064 13.3 1.4 0.13 12.3 1.4 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EGG24264.1 - 0.55 10.3 4.3 1.5 8.9 4.3 1.7 1 0 0 1 1 1 0 Double zinc ribbon Flavodoxin_NdrI PF07972.11 EGG24264.1 - 0.69 10.1 3.9 10 6.3 0.8 2.9 3 0 0 3 3 3 0 NrdI Flavodoxin like zf-RING_5 PF14634.6 EGG24264.1 - 8.6 6.4 10.1 4.4 7.4 0.2 2.8 2 0 0 2 2 2 0 zinc-RING finger domain Ebp2 PF05890.12 EGG24265.1 - 0.037 13.6 3.1 0.1 12.2 3.1 1.7 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 UbiA PF01040.18 EGG24266.1 - 1.2e-17 64.1 8.0 1.9e-17 63.4 8.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Mss4 PF04421.13 EGG24266.1 - 0.12 12.6 1.7 0.44 10.7 0.7 2.2 2 0 0 2 2 2 0 Mss4 protein Ank_2 PF12796.7 EGG24268.1 - 2.3e-23 82.6 4.6 1e-05 26.0 0.0 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24268.1 - 1.5e-21 76.4 9.9 1.9e-05 25.1 0.1 5.7 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24268.1 - 2.6e-17 62.7 6.1 0.0012 19.1 0.0 8.0 1 1 8 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24268.1 - 1.7e-13 49.4 0.7 0.32 11.7 0.0 7.9 7 1 2 9 9 9 4 Ankyrin repeat Ank PF00023.30 EGG24268.1 - 0.0046 17.4 0.6 49 4.6 0.1 5.4 3 2 1 4 4 4 0 Ankyrin repeat tRNA_bind PF01588.20 EGG24268.1 - 0.0054 16.8 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 2 Putative tRNA binding domain LRR_1 PF00560.33 EGG24269.1 - 0.0056 17.1 6.5 1.3e+02 3.8 0.0 7.3 6 0 0 6 6 6 1 Leucine Rich Repeat FNIP PF05725.12 EGG24270.1 - 6e-07 29.5 21.7 0.14 12.4 0.1 7.5 5 2 2 8 8 8 5 FNIP Repeat F-box-like PF12937.7 EGG24270.1 - 0.019 14.8 0.1 0.045 13.6 0.1 1.6 1 0 0 1 1 1 0 F-box-like SpoIIIAH PF12685.7 EGG24270.1 - 1.1 9.1 21.0 8.9 6.1 14.1 3.0 3 0 0 3 3 3 0 SpoIIIAH-like protein Suf PF05843.14 EGG24270.1 - 3.9 7.4 16.6 1.5 8.7 12.9 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SPX PF03105.19 EGG24271.1 - 0.0097 15.9 11.7 0.013 15.4 11.7 1.1 1 0 0 1 1 1 1 SPX domain TcdB_N PF12918.7 EGG24271.1 - 0.23 11.8 2.3 0.45 10.8 2.3 1.5 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain Macoilin PF09726.9 EGG24271.1 - 0.28 9.7 9.0 0.31 9.5 9.0 1.1 1 0 0 1 1 1 0 Macoilin family QWRF PF04484.12 EGG24271.1 - 1.4 8.6 9.1 1.7 8.3 9.1 1.1 1 0 0 1 1 1 0 QWRF family RAP1 PF07218.11 EGG24271.1 - 1.6 6.9 15.1 1.9 6.6 15.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.9 EGG24271.1 - 1.9 7.2 10.7 2.9 6.7 10.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Metallophos PF00149.28 EGG24273.1 - 2.9e-35 122.7 0.7 5.4e-35 121.7 0.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase P5-ATPase PF12409.8 EGG24273.1 - 2.3e-15 56.8 0.1 7.3e-15 55.2 0.1 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 EGG24273.1 - 1.1e-13 51.9 0.0 2.2e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase STPPase_N PF16891.5 EGG24273.1 - 0.00087 19.7 0.1 0.0022 18.4 0.1 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF2140 PF09911.9 EGG24273.1 - 0.074 12.6 0.7 0.16 11.5 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Glyco_hydro_65N PF03636.15 EGG24273.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain CPSF100_C PF13299.6 EGG24274.1 - 0.53 10.4 2.7 1.1 9.4 2.7 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Menin PF05053.13 EGG24274.1 - 5.7 5.2 6.9 8.2 4.6 6.9 1.2 1 0 0 1 1 1 0 Menin CRIM PF16978.5 EGG24275.1 - 9e-12 45.3 0.0 2.6e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EGG24275.1 - 3.6e-07 30.4 1.8 3.6e-07 30.4 1.8 1.8 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RBD PF02196.15 EGG24275.1 - 1.5e-06 28.2 0.0 3.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Raf-like Ras-binding domain dsRBD2 PF17842.1 EGG24275.1 - 0.14 12.4 2.5 12 6.1 0.3 3.3 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 MR_MLE_C PF13378.6 EGG24276.1 - 5.2e-22 78.5 0.0 1.3e-21 77.2 0.0 1.5 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EGG24276.1 - 0.00035 19.8 0.0 0.00055 19.2 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus HTH_45 PF14947.6 EGG24276.1 - 0.0026 17.7 0.0 0.0063 16.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix MR_MLE_N PF02746.16 EGG24276.1 - 0.0041 17.3 0.1 0.068 13.4 0.0 2.5 3 0 0 3 3 3 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PLDc_2 PF13091.6 EGG24277.1 - 1.7e-37 128.3 0.0 1.2e-21 77.0 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGG24277.1 - 1.6e-13 50.2 2.5 4e-07 29.9 0.2 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif SR-25 PF10500.9 EGG24277.1 - 2.6 7.6 14.3 0.14 11.8 6.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Dehydratase_MU PF02288.15 EGG24278.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Dehydratase medium subunit CDC45 PF02724.14 EGG24279.1 - 0.0034 15.8 0.5 0.0034 15.8 0.5 1.6 2 0 0 2 2 2 1 CDC45-like protein EIIBC-GUT_N PF03612.14 EGG24279.1 - 0.0073 16.1 0.0 0.58 9.9 0.1 2.6 2 0 0 2 2 2 1 Sorbitol phosphotransferase enzyme II N-terminus Cwf_Cwc_15 PF04889.12 EGG24279.1 - 0.0081 15.9 7.4 0.0081 15.9 7.4 2.7 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein DUF3381 PF11861.8 EGG24279.1 - 0.029 14.2 9.9 0.064 13.1 9.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) U1snRNP70_N PF12220.8 EGG24279.1 - 0.031 14.9 2.8 0.15 12.7 2.8 2.2 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Phage_ASH PF10554.9 EGG24279.1 - 0.042 14.2 0.1 5.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Ash protein family TRAP_alpha PF03896.16 EGG24279.1 - 0.16 11.1 1.9 0.32 10.1 1.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4484 PF14831.6 EGG24279.1 - 0.84 9.6 5.2 1.9 8.4 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) YL1 PF05764.13 EGG24279.1 - 1.5 8.8 15.4 0.026 14.7 6.8 2.2 2 0 0 2 2 2 0 YL1 nuclear protein CBM32 PF18344.1 EGG24280.1 - 0.062 13.2 3.2 1.4 8.8 0.3 3.3 2 1 0 2 2 2 0 Carbohydrate binding module family 32 F-box-like_2 PF13013.6 EGG24280.1 - 0.085 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 F-box-like domain Xpo1 PF08389.12 EGG24281.1 - 0.0042 17.2 0.2 0.05 13.7 0.1 2.5 3 0 0 3 3 3 1 Exportin 1-like protein LRR_4 PF12799.7 EGG24281.1 - 1.8 9.1 6.2 18 5.9 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF4359 PF14271.6 EGG24282.1 - 0.045 14.5 0.1 4.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4359) DnaJ PF00226.31 EGG24283.1 - 1.5e-21 76.2 0.4 2.4e-21 75.6 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain Mito_carr PF00153.27 EGG24283.1 - 2.2e-06 27.5 0.1 0.024 14.6 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein SNRNP27 PF08648.12 EGG24285.1 - 9e-12 44.9 1.1 9e-12 44.9 1.1 2.1 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins PTPLA PF04387.14 EGG24287.1 - 3.1e-55 186.4 9.3 4.6e-55 185.8 9.3 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF4203 PF13886.6 EGG24288.1 - 8e-07 28.9 32.3 1.1e-06 28.5 32.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) ThrE PF06738.12 EGG24288.1 - 0.15 11.4 12.9 0.048 13.0 8.9 1.9 2 0 0 2 2 2 0 Putative threonine/serine exporter TBCC PF07986.12 EGG24289.1 - 5.5e-29 100.3 5.0 1.5e-28 99.0 4.5 2.1 1 1 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EGG24289.1 - 9.5e-17 61.5 12.9 9.5e-17 61.5 12.9 2.3 2 1 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain ImpA_N PF06812.12 EGG24289.1 - 0.013 15.6 0.4 0.013 15.6 0.4 1.7 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system Y2_Tnp PF04986.13 EGG24289.1 - 0.11 12.5 0.9 0.64 10.0 0.0 2.2 2 0 0 2 2 2 0 Putative transposase adh_short PF00106.25 EGG24290.1 - 1.7e-49 168.0 0.6 2.8e-49 167.3 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG24290.1 - 8.7e-37 126.9 0.1 1.2e-36 126.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG24290.1 - 3.8e-11 43.2 0.1 5.3e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGG24290.1 - 7.1e-06 25.6 0.0 9.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EGG24290.1 - 3.9e-05 23.6 0.1 0.00046 20.1 0.2 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EGG24290.1 - 0.0096 15.4 0.1 0.02 14.3 0.1 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGG24290.1 - 0.03 13.4 0.2 0.064 12.3 0.1 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGG24290.1 - 0.08 12.1 0.1 11 5.1 0.0 2.7 3 0 0 3 3 3 0 Male sterility protein HPP PF04982.13 EGG24291.1 - 8.5e-40 135.7 6.8 1.9e-39 134.6 6.8 1.6 1 0 0 1 1 1 1 HPP family Zn_ribbon_17 PF17120.5 EGG24291.1 - 2.3e-09 36.7 14.1 2.3e-09 36.7 14.1 2.3 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EGG24291.1 - 7.1e-09 36.2 16.0 0.51 11.3 0.3 8.0 7 0 0 7 7 7 4 WD domain, G-beta repeat zinc_ribbon_16 PF17034.5 EGG24291.1 - 9e-06 25.9 20.5 0.019 15.1 20.5 3.7 1 1 0 1 1 1 1 Zinc-ribbon like family zf-RING_2 PF13639.6 EGG24291.1 - 0.98 9.8 17.7 0.71 10.3 5.5 2.7 2 0 0 2 2 2 0 Ring finger domain eIF3_p135 PF12807.7 EGG24292.1 - 0.25 11.3 2.5 0.25 11.3 0.2 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 TIG PF01833.24 EGG24293.1 - 6.6e-44 147.9 73.8 2.8e-12 46.5 5.8 14.8 11 1 2 13 13 13 9 IPT/TIG domain DNase_II PF03265.15 EGG24293.1 - 2.4e-22 79.7 10.6 7.5e-16 58.3 9.0 2.9 1 1 1 2 2 2 2 Deoxyribonuclease II TIG PF01833.24 EGG24294.1 - 3.2e-45 152.1 112.8 2.3e-11 43.6 7.3 12.8 12 0 0 12 12 12 11 IPT/TIG domain DNase_II PF03265.15 EGG24294.1 - 1.5e-29 103.3 6.0 1.2e-28 100.3 6.0 2.2 1 1 0 1 1 1 1 Deoxyribonuclease II DUF5421 PF17458.2 EGG24294.1 - 0.5 9.7 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5421) Ank_2 PF12796.7 EGG24295.1 - 0.00018 22.1 0.2 0.00018 22.1 0.2 1.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24295.1 - 0.0026 18.3 0.2 1.3 9.7 0.1 3.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24295.1 - 0.006 16.9 1.6 8 6.9 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24295.1 - 0.034 14.7 0.5 28 5.7 0.0 3.8 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 EGG24296.1 - 8.6e-22 77.2 3.4 8.5e-07 29.4 0.0 6.6 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG24296.1 - 4e-18 65.8 3.5 2e-06 28.3 0.0 4.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG24296.1 - 7.9e-14 51.5 3.4 0.0011 19.2 0.1 6.4 4 3 4 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24296.1 - 6.1e-12 44.6 3.5 0.11 13.1 0.0 8.1 10 0 0 10 10 10 2 Ankyrin repeat DUF3447 PF11929.8 EGG24296.1 - 1.6e-05 24.7 0.1 0.63 10.0 0.0 3.7 3 1 0 3 3 3 2 Domain of unknown function (DUF3447) Ank PF00023.30 EGG24296.1 - 0.00072 19.9 6.2 4.6 7.9 0.0 6.0 6 2 1 7 7 7 1 Ankyrin repeat DUF249 PF03158.13 EGG24296.1 - 0.03 14.0 0.9 0.42 10.3 0.1 3.0 1 1 2 3 3 3 0 Multigene family 530 protein GrpE PF01025.19 EGG24297.1 - 2.8e-47 160.5 9.1 3.6e-47 160.1 9.1 1.1 1 0 0 1 1 1 1 GrpE SPATA1_C PF15743.5 EGG24297.1 - 0.07 13.2 8.4 0.11 12.6 8.4 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus Abhydrolase_6 PF12697.7 EGG24298.1 - 4.9e-15 56.7 0.0 8.9e-15 55.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG24298.1 - 2.9e-10 39.8 0.0 9.9e-09 34.8 0.0 2.5 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG24298.1 - 1.8e-06 27.8 0.1 8.5e-05 22.3 0.1 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EGG24298.1 - 0.00032 20.5 0.0 0.00067 19.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EGG24298.1 - 0.0013 18.7 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase DUF2974 PF11187.8 EGG24298.1 - 0.03 13.9 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) EXOSC1 PF10447.9 EGG24299.1 - 1.9e-14 54.2 5.8 2.2e-11 44.3 0.2 3.0 2 1 1 3 3 3 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EGG24299.1 - 9.5e-14 50.9 0.1 2.2e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region LETM1 PF07766.13 EGG24300.1 - 1e-21 77.5 4.6 1.4e-10 41.0 0.1 2.1 1 1 1 2 2 2 2 LETM1-like protein LETM1 PF07766.13 EGG24301.1 - 2.1e-26 92.8 6.9 2.1e-26 92.8 6.9 2.1 1 1 1 2 2 2 1 LETM1-like protein PPP4R2 PF09184.11 EGG24301.1 - 0.0032 17.1 30.9 0.0057 16.3 19.1 2.1 2 0 0 2 2 2 2 PPP4R2 RPN2_C PF18004.1 EGG24301.1 - 0.006 16.5 26.4 0.0087 16.0 14.3 2.3 2 0 0 2 2 2 2 26S proteasome regulatory subunit RPN2 C-terminal domain ESM4 PF15952.5 EGG24301.1 - 0.0082 16.6 9.3 0.0082 16.6 9.3 2.6 2 1 0 2 2 2 1 Enhancer of split M4 family Vfa1 PF08432.10 EGG24301.1 - 0.16 12.3 34.1 0.18 12.1 17.1 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CNDH2_C PF16858.5 EGG24301.1 - 0.24 11.2 29.4 0.048 13.5 6.9 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CCSAP PF15748.5 EGG24301.1 - 2.2 8.4 30.3 0.16 12.1 14.6 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated CobT PF06213.12 EGG24301.1 - 3.7 6.9 26.8 3.8 6.8 5.4 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 EGG24301.1 - 5.2 5.7 27.6 0.78 8.4 5.3 2.3 2 0 0 2 2 2 0 Presenilin Actin PF00022.19 EGG24303.1 - 2.5e-57 194.4 0.0 1.7e-53 181.7 0.0 3.0 1 1 0 1 1 1 1 Actin Actin PF00022.19 EGG24304.1 - 6.2e-149 496.0 0.0 2e-148 494.4 0.0 1.6 1 1 0 1 1 1 1 Actin Actin PF00022.19 EGG24305.1 - 1.2e-117 393.0 0.0 3.6e-117 391.4 0.0 1.6 1 1 0 1 1 1 1 Actin FSA_C PF10479.9 EGG24305.1 - 1.1 7.3 7.4 1.7 6.7 7.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Actin PF00022.19 EGG24306.1 - 6.1e-126 420.3 0.0 1.5e-125 419.0 0.0 1.6 1 1 0 1 1 1 1 Actin CN_hydrolase PF00795.22 EGG24309.1 - 1.1e-51 175.7 0.0 1.3e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Y1_Tnp PF01797.16 EGG24309.1 - 0.072 13.2 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Transposase IS200 like TPR_12 PF13424.6 EGG24310.1 - 2.8e-10 40.3 3.1 2.6e-08 34.0 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG24310.1 - 8.6e-07 28.5 3.9 0.00064 19.4 1.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGG24310.1 - 9.5e-07 28.2 0.2 2.2e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.17 EGG24310.1 - 4.8e-06 26.3 4.3 0.02 15.0 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGG24310.1 - 0.00016 21.7 3.5 0.086 13.1 1.2 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF2225 PF09986.9 EGG24310.1 - 0.00071 19.4 0.8 0.002 17.9 0.4 1.8 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_19 PF14559.6 EGG24310.1 - 0.015 15.8 2.9 0.96 10.0 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGG24310.1 - 1.6 8.5 5.4 8.6 6.1 2.2 3.2 2 1 0 2 2 2 0 TPR repeat Coiled PF05710.12 EGG24311.1 - 4.9e-05 24.1 8.5 5.5e-05 23.9 8.5 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 EGG24312.1 - 0.00069 20.4 11.6 0.0008 20.2 11.6 1.1 1 0 0 1 1 1 1 Coiled coil Enolase_C PF00113.22 EGG24313.1 - 1.8e-146 487.0 0.0 2.3e-146 486.7 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGG24313.1 - 3.3e-61 205.2 0.3 5.6e-61 204.5 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGG24313.1 - 3.2e-09 36.7 0.0 5.3e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EGG24313.1 - 3.7e-06 26.3 0.1 8.6e-06 25.1 0.1 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MAAL_N PF05034.13 EGG24313.1 - 0.035 13.7 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase N-terminus MR_MLE_N PF02746.16 EGG24313.1 - 0.066 13.4 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Ank_2 PF12796.7 EGG24314.1 - 2.1e-30 105.1 11.9 2.1e-07 31.4 0.2 7.6 3 3 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG24314.1 - 2.8e-24 84.9 13.3 0.0048 17.2 0.0 11.4 4 2 8 12 12 12 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG24314.1 - 1.5e-23 82.9 8.7 0.00081 19.9 0.1 9.9 5 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24314.1 - 3.9e-15 54.4 3.7 1.8 9.4 0.1 11.1 12 0 0 12 12 12 2 Ankyrin repeat DUF5049 PF16468.5 EGG24314.1 - 4.6e-07 29.6 1.4 0.92 9.5 0.0 7.6 6 1 3 9 9 9 2 Domain of unknown function (DUF5049) Ank PF00023.30 EGG24314.1 - 0.0013 19.0 1.2 3.5e+02 1.9 0.0 7.6 7 3 1 8 8 8 0 Ankyrin repeat DUF748 PF05359.11 EGG24314.1 - 0.039 14.1 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) DUF3310 PF11753.8 EGG24314.1 - 0.067 13.4 0.0 0.68 10.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknwon function (DUF3310) Ndc80_HEC PF03801.13 EGG24314.1 - 0.12 12.0 3.1 43 3.7 0.4 4.3 4 0 0 4 4 4 0 HEC/Ndc80p family MFS_1 PF07690.16 EGG24315.1 - 1.7e-24 86.5 40.5 5.9e-23 81.4 40.7 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EGG24315.1 - 5e-09 35.1 13.6 4.3e-08 32.0 13.6 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGG24315.1 - 3.5e-05 22.9 9.4 7.8e-05 21.7 9.4 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter Peptidase_C93 PF06035.11 EGG24315.1 - 0.023 14.5 0.3 0.055 13.3 0.3 1.6 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Methyltransf_12 PF08242.12 EGG24315.1 - 0.28 12.0 2.4 54 4.6 0.0 3.5 3 0 0 3 3 3 0 Methyltransferase domain Pkinase PF00069.25 EGG24316.1 - 3e-34 118.6 0.0 1.4e-22 80.3 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG24316.1 - 1.2e-20 73.9 0.0 1.2e-12 47.7 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase WD40 PF00400.32 EGG24316.1 - 2.2e-20 72.6 19.2 6.6e-05 23.6 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat PB1 PF00564.24 EGG24316.1 - 1.3e-09 37.9 0.0 2.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 PB1 domain F-box PF00646.33 EGG24316.1 - 5.5e-08 32.5 0.1 1.1e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGG24316.1 - 1.9e-05 24.4 0.1 3.5e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like Spt20 PF12090.8 EGG24317.1 - 1.1e-13 51.4 0.6 1.1e-13 51.4 0.6 11.8 3 3 6 9 9 9 1 Spt20 family Mitoc_mL59 PF18126.1 EGG24318.1 - 0.22 11.8 14.9 0.54 10.6 9.8 3.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein mL59 Ank_2 PF12796.7 EGG24319.1 - 1.8e-28 99.0 13.8 9e-07 29.4 0.1 6.3 3 3 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24319.1 - 7.4e-28 96.6 11.6 1.1e-06 29.1 0.0 8.7 8 2 1 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24319.1 - 5.3e-23 80.8 12.4 0.00052 20.2 0.0 10.6 3 3 7 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24319.1 - 2.6e-10 39.6 6.8 11 7.0 0.0 10.7 11 0 0 11 11 11 1 Ankyrin repeat DUF5049 PF16468.5 EGG24319.1 - 4.7e-05 23.2 8.2 5.2 7.0 0.0 8.3 6 2 5 11 11 11 2 Domain of unknown function (DUF5049) Ank PF00023.30 EGG24319.1 - 0.00032 21.0 2.1 6.7 7.4 0.0 6.8 6 2 1 7 7 7 1 Ankyrin repeat AAL_decarboxy PF03306.13 EGG24319.1 - 0.036 13.4 0.2 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase FaeA PF04703.12 EGG24319.1 - 0.041 14.3 0.2 5.2 7.5 0.0 3.4 3 1 1 4 4 4 0 FaeA-like protein DUF249 PF03158.13 EGG24319.1 - 0.16 11.6 2.3 48 3.6 0.1 4.4 3 1 1 4 4 4 0 Multigene family 530 protein FAM25 PF15825.5 EGG24319.1 - 0.63 10.4 2.3 5.3 7.5 0.0 3.3 2 1 1 3 3 3 0 FAM25 family ABC2_membrane PF01061.24 EGG24321.1 - 1.4e-66 223.9 49.7 2.7e-43 147.9 21.4 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGG24321.1 - 7.6e-31 107.5 0.0 4.7e-18 66.0 0.0 2.9 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EGG24321.1 - 3.6e-22 78.1 13.3 2e-21 75.7 0.1 3.5 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 EGG24321.1 - 1.2e-08 34.5 52.6 5.4e-06 25.8 14.6 3.2 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 EGG24321.1 - 3.7e-08 33.9 0.1 9.3e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EGG24321.1 - 9.3e-07 28.9 0.0 0.0021 18.0 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase AAA_21 PF13304.6 EGG24321.1 - 1.4e-06 28.3 0.0 0.0063 16.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGG24321.1 - 1.3e-05 24.8 0.1 0.011 15.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG24321.1 - 0.0002 21.8 0.0 0.43 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGG24321.1 - 0.00069 19.9 0.0 0.23 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGG24321.1 - 0.0019 17.8 0.0 0.01 15.4 0.1 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGG24321.1 - 0.002 18.2 0.9 2.5 8.2 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 EGG24321.1 - 0.0033 17.6 0.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGG24321.1 - 0.0047 16.7 0.2 1.3 8.7 0.3 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGG24321.1 - 0.0052 16.1 0.0 0.99 8.6 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin cobW PF02492.19 EGG24321.1 - 0.0088 15.6 0.2 0.21 11.2 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EGG24321.1 - 0.016 15.6 0.2 7.7 7.0 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EGG24321.1 - 0.045 14.2 0.1 0.045 14.2 0.1 2.8 3 1 1 4 4 2 0 AAA domain NACHT PF05729.12 EGG24321.1 - 0.13 12.2 0.3 7 6.5 0.4 2.5 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EGG24321.1 - 0.14 12.1 0.1 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EGG24321.1 - 0.15 11.8 0.1 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 EGG24321.1 - 0.18 12.3 6.8 0.53 10.8 0.0 3.5 4 0 0 4 4 3 0 AAA domain RuvB_N PF05496.12 EGG24321.1 - 0.31 10.8 0.6 18 5.0 0.0 2.8 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGG24321.1 - 9.1 6.5 6.0 2.9 8.1 0.7 2.6 3 0 0 3 3 2 0 AAA domain PH PF00169.29 EGG24323.1 - 3.5e-11 43.5 8.0 3.2e-08 34.0 2.9 2.9 2 1 1 3 3 3 2 PH domain PH_8 PF15409.6 EGG24323.1 - 6.3e-05 23.2 6.7 0.00017 21.8 0.4 3.3 3 1 1 4 4 4 1 Pleckstrin homology domain PH_11 PF15413.6 EGG24323.1 - 7.6e-05 23.1 12.7 0.00043 20.7 8.0 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain DUF1016_N PF17761.1 EGG24323.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 DUF1016 N-terminal domain MRP-L27 PF09809.9 EGG24324.1 - 7.9e-10 38.6 0.2 9.2e-10 38.4 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 TRAM_2 PF18693.1 EGG24325.1 - 0.036 14.2 0.0 0.13 12.4 0.0 1.8 1 1 1 2 2 2 0 TRAM domain COG7 PF10191.9 EGG24325.1 - 0.11 10.8 0.0 0.13 10.5 0.0 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DEAD PF00270.29 EGG24326.1 - 6.1e-50 169.4 0.1 2.5e-48 164.2 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG24326.1 - 1.3e-26 93.1 0.0 1.2e-25 89.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG24326.1 - 1.4e-05 25.2 0.0 1.4e-05 25.2 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit TFIIA PF03153.13 EGG24326.1 - 4 7.3 30.3 0.21 11.6 24.5 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Dicty_CAR PF05462.11 EGG24327.1 - 2.5e-11 43.3 16.0 2.5e-11 43.3 16.0 1.7 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 EGG24327.1 - 9.3e-07 28.4 21.3 9.7e-07 28.4 20.1 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) PH PF00169.29 EGG24328.1 - 4.4e-11 43.2 0.0 1e-10 42.0 0.0 1.6 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 EGG24328.1 - 4.4e-05 23.9 0.8 0.00019 21.8 0.8 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EGG24328.1 - 0.001 19.3 0.1 1.1 9.5 0.0 2.6 1 1 1 2 2 2 2 Pleckstrin homology domain Colicin_M PF14859.6 EGG24328.1 - 0.0095 15.1 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 1 Colicin M pP_pnuc_1 PF18165.1 EGG24328.1 - 0.06 13.2 0.1 6.1 6.7 0.0 2.7 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease DUF3752 PF12572.8 EGG24329.1 - 4e-21 76.1 19.6 4e-21 76.1 19.6 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3752) Apolipoprotein PF01442.18 EGG24331.1 - 0.00036 20.5 20.0 0.0012 18.7 20.0 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EGG24331.1 - 0.0035 17.9 20.6 0.22 12.2 2.3 3.7 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EGG24331.1 - 0.027 15.0 33.6 0.27 11.8 2.7 5.7 2 1 1 3 3 3 0 YtxH-like protein DUF885 PF05960.11 EGG24331.1 - 0.61 9.7 8.6 1.3 8.6 8.6 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) ASL_C2 PF14698.6 EGG24331.1 - 0.69 10.7 1.9 56 4.6 0.1 2.8 1 1 1 2 2 2 0 Argininosuccinate lyase C-terminal RRF PF01765.19 EGG24331.1 - 1.3 8.9 25.3 0.23 11.4 3.5 3.9 1 1 0 3 3 3 0 Ribosome recycling factor ArnB_C PF18677.1 EGG24331.1 - 4.2 7.5 13.9 5.4 7.2 1.6 2.9 2 1 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain Copper-bind PF00127.20 EGG24332.1 - 0.00026 21.4 0.1 0.00042 20.7 0.1 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family DIX PF00778.17 EGG24332.1 - 0.075 12.9 0.3 0.19 11.6 0.3 1.6 1 0 0 1 1 1 0 DIX domain Patatin PF01734.22 EGG24333.1 - 4.3e-18 66.2 1.0 8e-18 65.4 1.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase A2M_recep PF07677.14 EGG24335.1 - 0.051 14.3 0.6 0.68 10.7 0.1 2.4 2 1 0 2 2 2 0 A-macroglobulin receptor binding domain MOZ_SAS PF01853.18 EGG24336.1 - 6.8e-89 296.3 1.1 1.5e-88 295.2 0.8 1.7 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 EGG24336.1 - 4.3e-27 93.5 4.3 4.3e-27 93.5 4.3 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 EGG24336.1 - 7.9e-19 67.3 1.7 1.7e-18 66.3 1.7 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EGG24336.1 - 0.0028 18.1 0.0 0.0056 17.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG24336.1 - 0.019 15.2 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-CXXC PF02008.20 EGG24336.1 - 0.74 9.9 3.6 2.4 8.3 3.6 1.8 1 0 0 1 1 1 0 CXXC zinc finger domain Radical_SAM PF04055.21 EGG24337.1 - 6.9e-13 49.3 0.0 2.2e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 EGG24337.1 - 6.5e-06 26.2 0.0 1.6e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 B12 binding domain Fer4_14 PF13394.6 EGG24337.1 - 0.13 12.4 0.1 5.4 7.2 0.0 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain MOZ_SAS PF01853.18 EGG24338.1 - 1.5e-68 230.0 0.8 9.8e-65 217.6 0.3 2.9 1 1 1 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 EGG24338.1 - 1.1e-26 92.1 3.8 2.4e-26 91.1 3.8 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EGG24338.1 - 2.4e-18 65.8 1.6 6e-18 64.5 1.6 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EGG24338.1 - 0.0083 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG24338.1 - 0.061 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family LRR_6 PF13516.6 EGG24338.1 - 3.9 7.8 5.3 0.74 10.0 0.1 2.8 3 0 0 3 3 3 0 Leucine Rich repeat Skp1_POZ PF03931.15 EGG24339.1 - 0.095 12.9 0.3 0.27 11.4 0.3 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain LRR_8 PF13855.6 EGG24339.1 - 0.1 12.4 1.6 0.77 9.6 0.5 2.8 2 1 0 2 2 2 0 Leucine rich repeat LRR_6 PF13516.6 EGG24339.1 - 0.24 11.5 9.4 1.4 9.2 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.7 EGG24339.1 - 0.52 10.8 11.8 0.29 11.6 0.8 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) cpYpsA PF12694.7 EGG24340.1 - 0.028 14.2 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family LRR_6 PF13516.6 EGG24341.1 - 0.0076 16.2 5.9 0.59 10.3 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 EGG24341.1 - 0.025 14.3 1.0 0.025 14.3 1.0 2.8 2 2 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 EGG24341.1 - 0.077 13.4 1.1 0.077 13.4 1.1 2.2 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGG24341.1 - 0.32 11.7 3.4 14 6.7 0.1 3.4 4 0 0 4 4 4 0 Leucine Rich Repeat CholecysA-Rec_N PF09193.10 EGG24341.1 - 3.7 7.6 6.1 1.2 9.2 1.2 2.4 2 1 1 3 3 3 0 Cholecystokinin A receptor, N-terminal LRR_6 PF13516.6 EGG24342.1 - 0.01 15.8 3.3 0.4 10.9 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 EGG24342.1 - 0.045 14.2 4.9 1.3 9.5 1.7 4.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) zf-B_box PF00643.24 EGG24342.1 - 0.054 13.7 1.5 0.16 12.2 1.5 1.8 1 0 0 1 1 1 0 B-box zinc finger zinc-ribbons_6 PF07191.12 EGG24342.1 - 0.072 13.1 0.7 0.2 11.7 0.7 1.7 1 0 0 1 1 1 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.7 EGG24342.1 - 0.21 11.6 1.7 0.51 10.3 1.7 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain LRR_6 PF13516.6 EGG24343.1 - 1.6 9.0 0.0 1.6 9.0 0.0 4.7 6 0 0 6 6 6 0 Leucine Rich repeat LRR_4 PF12799.7 EGG24344.1 - 0.58 10.7 5.7 5.6 7.5 0.4 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) TIG PF01833.24 EGG24345.1 - 3.9e-44 148.6 147.5 1.2e-07 31.7 1.0 18.3 16 3 3 19 19 19 14 IPT/TIG domain EGF_2 PF07974.13 EGG24345.1 - 4.6e-07 30.1 35.5 0.0018 18.6 13.0 2.7 2 0 0 2 2 2 2 EGF-like domain PRCC PF10253.9 EGG24345.1 - 1.1 10.0 5.5 2 9.1 5.5 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting EGF PF00008.27 EGG24345.1 - 5.4 7.4 33.9 0.97 9.8 7.6 3.0 3 0 0 3 3 3 0 EGF-like domain DAP3 PF10236.9 EGG24346.1 - 0.0053 16.0 0.0 0.067 12.4 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 Methyltransf_12 PF08242.12 EGG24347.1 - 0.1 13.4 2.1 5 7.9 2.3 2.3 2 0 0 2 2 2 0 Methyltransferase domain NinE PF05322.11 EGG24347.1 - 0.24 11.3 1.3 0.98 9.4 0.1 2.5 2 0 0 2 2 2 0 NINE Protein Pex2_Pex12 PF04757.14 EGG24347.1 - 0.47 10.0 2.2 0.69 9.5 2.2 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Apis_Csd PF11671.8 EGG24347.1 - 2.2 8.3 20.2 1.2 9.1 17.3 1.8 2 0 0 2 2 2 0 Complementary sex determiner protein zf-C3HC4_3 PF13920.6 EGG24347.1 - 3.1 7.7 19.8 0.19 11.6 9.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Complex1_LYR PF05347.15 EGG24348.1 - 6.4e-08 32.5 0.0 8.5e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGG24348.1 - 0.046 14.5 0.0 0.052 14.3 0.0 1.1 1 0 0 1 1 1 0 Complex1_LYR-like RRM_1 PF00076.22 EGG24349.1 - 5.6e-15 54.9 0.0 7.7e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG24349.1 - 0.00084 19.4 0.0 0.0022 18.1 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EGG24349.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 EGG24349.1 - 0.015 15.2 0.1 0.024 14.6 0.1 1.4 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EGG24349.1 - 0.073 13.3 0.0 0.17 12.1 0.0 1.6 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF4060 PF13269.6 EGG24349.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4060) AP2 PF00847.20 EGG24349.1 - 0.16 12.2 0.0 0.22 11.8 0.0 1.5 1 1 0 1 1 1 0 AP2 domain Vps54_N PF10475.9 EGG24350.1 - 1.1e-78 264.4 6.8 1.8e-78 263.8 5.7 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EGG24350.1 - 2.4e-75 253.3 2.8 2.4e-75 253.3 2.8 3.6 4 1 1 5 5 5 1 Protein of unknown function C-terminus (DUF2451) Dor1 PF04124.12 EGG24350.1 - 5.6e-05 22.0 5.3 0.0002 20.2 0.1 3.1 3 0 0 3 3 3 1 Dor1-like family SUIM_assoc PF16619.5 EGG24350.1 - 0.00082 19.4 2.5 0.0038 17.3 0.0 3.4 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 RNA_binding PF01877.17 EGG24350.1 - 0.0098 16.2 0.2 0.0098 16.2 0.2 3.5 4 1 1 5 5 5 1 RNA binding DUF3510 PF12022.8 EGG24350.1 - 0.03 14.7 1.1 0.26 11.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Vps54 PF07928.12 EGG24350.1 - 0.96 9.9 4.2 1.5 9.2 0.4 3.2 3 0 0 3 3 3 0 Vps54-like protein IBN_N PF03810.19 EGG24351.1 - 1.5e-09 37.7 0.9 9.9e-09 35.0 0.1 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGG24351.1 - 0.0049 16.9 4.2 0.0049 16.9 4.2 4.1 3 1 0 3 3 3 1 Exportin 1-like protein SeqA_N PF17206.3 EGG24351.1 - 0.033 13.5 0.6 10 5.6 0.1 3.5 3 0 0 3 3 3 0 SeqA protein N-terminal domain SAM_2 PF07647.17 EGG24352.1 - 2.4e-05 24.3 0.0 4.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DAP3 PF10236.9 EGG24352.1 - 0.0036 16.5 0.0 0.0071 15.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 SAM_1 PF00536.30 EGG24352.1 - 0.016 15.6 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 EGG24352.1 - 0.21 11.9 2.4 0.45 10.8 0.1 2.6 3 0 0 3 3 3 0 Ste50p, sterile alpha motif Lipase_3 PF01764.25 EGG24354.1 - 6e-13 48.9 0.0 2e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Esterase PF00756.20 EGG24354.1 - 0.036 13.7 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 EGG24354.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain G-gamma PF00631.22 EGG24355.1 - 1.6e-16 60.0 0.1 1.7e-16 59.9 0.1 1.0 1 0 0 1 1 1 1 GGL domain RNA_pol_Rpb1_1 PF04997.12 EGG24355.1 - 0.051 12.9 0.0 0.06 12.7 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 RRM_1 PF00076.22 EGG24356.1 - 6.4e-59 195.7 1.1 3.3e-19 68.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EGG24356.1 - 0.00069 19.8 0.1 17 5.7 0.0 3.3 2 1 1 3 3 3 2 BRCA1-associated protein 2 Nup35_RRM_2 PF14605.6 EGG24356.1 - 0.019 15.0 0.1 0.85 9.7 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGG24356.1 - 0.021 14.8 8.2 0.64 10.1 0.0 4.1 4 0 0 4 4 4 0 RNA binding motif RRM_7 PF16367.5 EGG24356.1 - 0.022 14.9 10.7 1.5 9.0 0.1 4.9 5 0 0 5 5 5 0 RNA recognition motif RRM_occluded PF16842.5 EGG24356.1 - 0.022 14.6 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif SUIM_assoc PF16619.5 EGG24356.1 - 0.24 11.5 0.0 0.24 11.5 0.0 8.0 5 4 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 ELFV_dehydrog_N PF02812.18 EGG24357.1 - 1.2e-55 186.9 0.0 2.3e-55 186.0 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 EGG24357.1 - 2.7e-55 187.7 0.2 2e-53 181.6 0.0 2.2 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 EGG24357.1 - 0.0012 18.3 0.1 0.0023 17.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EGG24357.1 - 0.0037 17.4 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 EGG24357.1 - 0.0048 17.3 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Bac_GDH PF05088.12 EGG24357.1 - 0.035 11.6 0.0 1.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase E1_4HB PF16191.5 EGG24357.1 - 0.14 12.4 0.0 0.65 10.2 0.0 2.2 3 0 0 3 3 3 0 Ubiquitin-activating enzyme E1 four-helix bundle RRS1 PF04939.12 EGG24358.1 - 9.7e-50 168.6 4.9 9.7e-50 168.6 4.9 1.5 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) PPARgamma_N PF12577.8 EGG24358.1 - 0.087 13.5 0.1 0.23 12.1 0.1 1.7 1 0 0 1 1 1 0 PPAR gamma N-terminal region Nckap1 PF09735.9 EGG24359.1 - 0 1290.7 3.9 0 1290.4 3.9 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein DDE_Tnp_ISL3 PF01610.17 EGG24359.1 - 0.014 15.1 0.4 0.15 11.8 0.0 2.8 3 0 0 3 3 3 0 Transposase Peptidase_M49 PF03571.15 EGG24361.1 - 5.9e-46 157.0 0.8 8.8e-39 133.3 0.1 2.1 1 1 1 2 2 2 2 Peptidase family M49 Ytp1 PF10355.9 EGG24361.1 - 0.23 10.7 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) EGF_2 PF07974.13 EGG24362.1 - 0.027 14.8 10.9 0.066 13.6 10.9 1.7 1 0 0 1 1 1 0 EGF-like domain SKG6 PF08693.10 EGG24362.1 - 0.5 9.8 3.4 1.3 8.5 3.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3844 PF12955.7 EGG24362.1 - 0.53 10.4 3.8 1.2 9.3 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) FNIP PF05725.12 EGG24363.1 - 1.7e-14 53.7 38.5 3.4e-05 23.9 0.3 8.3 6 2 3 9 9 9 7 FNIP Repeat FNIP PF05725.12 EGG24365.1 - 5.9e-15 55.2 32.2 5.1e-06 26.6 0.4 8.9 7 1 3 10 10 10 6 FNIP Repeat DIOX_N PF14226.6 EGG24365.1 - 0.14 12.9 0.0 0.31 11.8 0.0 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal DUF2207 PF09972.9 EGG24366.1 - 0.01 14.7 0.1 0.03 13.1 0.1 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Pex24p PF06398.11 EGG24366.1 - 0.03 13.3 1.1 0.038 13.0 1.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin TMEM154 PF15102.6 EGG24366.1 - 0.037 13.9 0.7 0.075 12.9 0.7 1.4 1 0 0 1 1 1 0 TMEM154 protein family Peptidase_M56 PF05569.11 EGG24366.1 - 0.041 13.1 0.1 3.8 6.6 0.1 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 CstA PF02554.14 EGG24366.1 - 0.048 12.6 0.9 0.16 10.8 0.1 1.8 2 0 0 2 2 2 0 Carbon starvation protein CstA Orf78 PF06024.12 EGG24366.1 - 0.075 13.3 0.1 0.075 13.3 0.1 1.9 3 0 0 3 3 3 0 Orf78 (ac78) Profilin PF00235.19 EGG24367.1 - 3.5e-08 33.8 0.1 4.8e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Profilin FAM176 PF14851.6 EGG24368.1 - 0.0039 16.9 0.7 0.0039 16.9 0.7 1.8 2 0 0 2 2 2 1 FAM176 family SARAF PF06682.12 EGG24368.1 - 0.12 12.0 3.5 3.5 7.2 1.0 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DNA_pol_phi PF04931.13 EGG24368.1 - 0.2 9.7 8.3 0.3 9.2 8.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 EGG24368.1 - 1.3 8.6 7.1 0.57 9.7 4.7 1.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Serinc PF03348.15 EGG24368.1 - 2.7 6.8 6.2 0.36 9.7 2.3 1.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF2457 PF10446.9 EGG24368.1 - 5.9 5.9 14.1 10 5.1 14.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Fis1_TPR_C PF14853.6 EGG24369.1 - 1.8e-07 31.1 1.7 6e-07 29.4 1.3 2.2 1 1 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 EGG24369.1 - 0.058 13.9 0.5 0.17 12.4 0.5 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGG24369.1 - 0.099 12.5 0.2 0.23 11.3 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG24369.1 - 0.16 12.9 0.0 6.6 7.8 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3915 PF13054.6 EGG24369.1 - 0.73 9.8 10.6 1.2 9.1 1.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) Carb_bind PF10645.9 EGG24375.1 - 0.062 13.5 4.5 2.9 8.2 0.9 2.4 2 0 0 2 2 2 0 Carbohydrate binding DUF3430 PF11912.8 EGG24376.1 - 4e-05 23.8 0.8 4.5e-05 23.6 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) ODV-E18 PF10717.9 EGG24377.1 - 0.022 14.6 0.2 0.032 14.1 0.2 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Ank_4 PF13637.6 EGG24378.1 - 8.1e-28 96.4 7.1 7.9e-06 26.3 0.0 9.2 8 2 1 9 9 9 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG24378.1 - 1e-24 86.9 8.1 3.9e-06 27.4 0.0 5.9 2 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG24378.1 - 8.4e-18 62.6 4.2 5 8.0 0.0 11.4 11 1 1 12 12 12 4 Ankyrin repeat Ank_5 PF13857.6 EGG24378.1 - 4.5e-17 61.9 4.5 0.0062 16.8 0.0 9.1 7 2 4 11 11 11 5 Ankyrin repeats (many copies) Ank PF00023.30 EGG24378.1 - 0.15 12.6 3.9 39 4.9 0.1 5.6 6 1 0 6 6 6 0 Ankyrin repeat DUF3447 PF11929.8 EGG24378.1 - 1.2 9.2 23.6 0.59 10.1 0.7 7.1 3 2 6 9 9 9 0 Domain of unknown function (DUF3447) SdrD_B PF17210.3 EGG24379.1 - 7e-07 29.5 0.0 7e-07 29.5 0.0 3.7 2 1 0 3 3 3 1 SdrD B-like domain DUF2012 PF09430.10 EGG24379.1 - 0.036 14.2 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) TIG PF01833.24 EGG24380.1 - 1.7e-14 53.7 28.6 6e-09 35.9 9.8 4.6 4 0 0 4 4 4 4 IPT/TIG domain AAA_lid_2 PF17863.1 EGG24381.1 - 9.9e-12 44.5 0.0 2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 EGG24381.1 - 0.00036 20.4 0.1 0.00082 19.2 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 EGG24382.1 - 4.3e-07 29.6 0.0 5.7e-06 25.9 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGG24382.1 - 3.5e-05 22.8 0.0 5.3e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGG24382.1 - 0.0011 18.7 0.3 0.13 11.9 0.1 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGG24382.1 - 0.016 15.1 0.0 0.18 11.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family CHIP_TPR_N PF18391.1 EGG24382.1 - 1.3 9.8 5.4 24 5.8 1.3 3.2 3 0 0 3 3 3 0 CHIP N-terminal tetratricopeptide repeat domain SGS PF05002.15 EGG24383.1 - 3.5e-27 94.3 0.7 7.8e-27 93.2 0.7 1.7 1 0 0 1 1 1 1 SGS domain TPR_1 PF00515.28 EGG24383.1 - 7.1e-16 57.3 4.2 7.2e-06 25.6 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG24383.1 - 1.2e-15 56.2 1.1 0.0009 19.2 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGG24383.1 - 5.1e-14 51.7 2.2 1.6e-06 27.7 0.0 3.3 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 EGG24383.1 - 4.1e-13 48.4 2.2 0.00065 19.7 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat CS PF04969.16 EGG24383.1 - 1.6e-12 48.3 0.4 3.1e-12 47.3 0.4 1.5 1 0 0 1 1 1 1 CS domain TPR_16 PF13432.6 EGG24383.1 - 2.1e-09 37.9 0.0 1.7e-06 28.6 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG24383.1 - 2.4e-09 37.3 1.6 4.3e-09 36.5 1.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGG24383.1 - 4.8e-08 32.8 1.3 0.0013 19.0 0.1 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGG24383.1 - 1.9e-07 31.1 0.0 2.8e-06 27.4 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGG24383.1 - 1.1e-06 28.9 0.0 0.043 14.6 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGG24383.1 - 6.6e-05 23.3 0.2 0.2 12.2 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG24383.1 - 0.017 15.4 0.4 4.1 7.8 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG24383.1 - 0.028 15.0 0.0 10 7.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5113 PF17140.4 EGG24383.1 - 0.035 13.9 0.3 6.3 6.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) Fis1_TPR_C PF14853.6 EGG24383.1 - 0.043 13.9 0.8 10 6.3 0.1 2.8 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 EGG24383.1 - 0.048 12.6 0.0 0.47 9.3 0.0 1.9 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 EGG24383.1 - 0.1 12.7 0.9 7.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L16 PF00252.18 EGG24384.1 - 1.8e-40 138.0 0.0 2.5e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e NLPC_P60 PF00877.19 EGG24385.1 - 4.8e-12 45.8 0.1 7.6e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 NlpC/P60 family DUF2722 PF10846.8 EGG24386.1 - 0.037 13.0 2.0 0.15 11.0 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) AAA_lid_10 PF17872.1 EGG24386.1 - 0.14 12.3 0.4 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA lid domain SUIM_assoc PF16619.5 EGG24386.1 - 1.2 9.3 12.3 0.026 14.6 4.6 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FecR PF04773.13 EGG24388.1 - 0.013 16.1 0.4 0.045 14.4 0.4 1.9 1 0 0 1 1 1 0 FecR protein DUF3737 PF12541.8 EGG24388.1 - 0.026 13.7 0.7 0.054 12.7 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3737) F-box PF00646.33 EGG24390.1 - 0.0028 17.5 2.0 1.9 8.4 0.3 2.8 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 EGG24390.1 - 0.0085 16.0 0.4 2.3 8.2 0.1 3.0 2 0 0 2 2 2 2 F-box-like EF-hand_1 PF00036.32 EGG24391.1 - 5.8e-13 47.4 0.2 0.00091 18.6 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGG24391.1 - 4.5e-11 43.0 0.2 2.4e-06 27.9 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGG24391.1 - 5.1e-10 38.5 1.3 0.06 13.3 0.2 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EGG24391.1 - 1.2e-08 34.7 0.9 4.6e-06 26.4 0.2 3.1 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 EGG24391.1 - 3.3e-05 24.1 0.0 0.24 11.7 0.0 2.7 1 1 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 EGG24391.1 - 0.046 14.6 0.4 0.22 12.4 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain 2OG-FeII_Oxy_3 PF13640.6 EGG24392.1 - 2.8e-19 69.8 0.0 5.3e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EGG24392.1 - 9.9e-16 58.2 0.0 2.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.22 EGG24393.1 - 3.7e-16 58.7 0.1 6.5e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG24393.1 - 2.3e-05 24.4 0.0 7.1e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EGG24393.1 - 0.00078 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.9 EGG24393.1 - 8.6 4.8 19.9 10 4.5 19.9 1.1 1 0 0 1 1 1 0 Macoilin family LAP1C PF05609.12 EGG24393.1 - 9.8 5.1 17.0 11 4.9 17.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MMADHC PF10229.9 EGG24394.1 - 3.6e-30 105.6 0.0 4.6e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein NUP50 PF08911.11 EGG24395.1 - 1.1e-08 35.6 8.8 1.1e-08 35.6 8.8 2.8 2 1 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) RhoGEF PF00621.20 EGG24396.1 - 1.6e-45 155.6 7.8 1.6e-45 155.6 7.8 3.2 4 0 0 4 4 4 1 RhoGEF domain IQ PF00612.27 EGG24396.1 - 0.00017 21.1 0.6 0.00053 19.5 0.6 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF3824 PF12868.7 EGG24396.1 - 7.7 7.2 9.7 19 5.9 9.7 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Use1 PF09753.9 EGG24397.1 - 1.3e-23 84.0 13.4 8.5e-20 71.5 3.2 3.1 3 1 0 3 3 3 2 Membrane fusion protein Use1 VBS PF08913.10 EGG24397.1 - 0.03 14.8 0.7 0.22 12.0 0.1 2.2 2 0 0 2 2 2 0 Vinculin Binding Site LRR_6 PF13516.6 EGG24398.1 - 5.9e-13 47.7 19.8 0.0034 17.3 0.2 8.3 9 0 0 9 9 9 5 Leucine Rich repeat Carm_PH PF17888.1 EGG24398.1 - 0.022 15.1 0.2 0.08 13.3 0.1 2.1 2 0 0 2 2 2 0 Carmil pleckstrin homology domain LRR_1 PF00560.33 EGG24398.1 - 0.022 15.2 14.7 33 5.6 0.1 7.4 8 0 0 8 8 8 0 Leucine Rich Repeat DUF3987 PF13148.6 EGG24398.1 - 0.12 11.4 0.5 0.19 10.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) LRR_4 PF12799.7 EGG24398.1 - 0.19 12.2 22.4 0.26 11.8 1.3 6.9 5 1 4 9 9 9 0 Leucine Rich repeats (2 copies) F-box PF00646.33 EGG24399.1 - 8.9e-07 28.6 2.5 0.013 15.4 0.0 4.0 4 0 0 4 4 4 2 F-box domain HTH_44 PF14641.6 EGG24399.1 - 0.00065 20.1 1.6 0.17 12.3 0.1 2.7 2 0 0 2 2 2 2 Helix-turn-helix DNA-binding domain of SPT6 F-box-like PF12937.7 EGG24399.1 - 0.016 15.1 0.2 6.6 6.7 0.0 3.4 3 0 0 3 3 3 0 F-box-like Adenine_glyco PF03352.13 EGG24400.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Methyladenine glycosylase Reticulon PF02453.17 EGG24401.1 - 6.8e-10 39.1 8.6 1e-09 38.6 8.6 1.3 1 0 0 1 1 1 1 Reticulon DUF3566 PF12089.8 EGG24401.1 - 0.85 10.0 5.2 2.7 8.4 1.9 2.7 2 1 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) UbiA PF01040.18 EGG24401.1 - 2.2 7.5 10.7 0.067 12.5 2.4 2.1 2 0 0 2 2 2 0 UbiA prenyltransferase family VirB3 PF05101.13 EGG24401.1 - 8.9 6.6 8.4 22 5.3 1.9 2.4 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Voltage_CLC PF00654.20 EGG24402.1 - 6.9e-69 232.8 27.3 6.9e-69 232.8 27.3 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGG24402.1 - 9.3e-10 38.8 0.3 2.1e-05 24.9 0.0 2.9 3 0 0 3 3 3 2 CBS domain Myc_N PF01056.18 EGG24402.1 - 0.89 9.4 10.6 0.86 9.4 9.6 1.4 1 1 0 1 1 1 0 Myc amino-terminal region EGF_2 PF07974.13 EGG24403.1 - 0.00017 21.9 10.8 0.00017 21.9 10.8 2.2 3 0 0 3 3 3 1 EGF-like domain EGF_Tenascin PF18720.1 EGG24403.1 - 0.26 11.4 10.4 0.81 9.8 10.4 1.9 1 0 0 1 1 1 0 Tenascin EGF domain Laminin_EGF PF00053.24 EGG24403.1 - 4.9 7.4 13.3 0.067 13.3 5.9 1.7 2 0 0 2 2 2 0 Laminin EGF domain Exo70 PF03081.15 EGG24404.1 - 1.3e-36 126.4 16.4 1.3e-36 126.4 16.4 2.5 3 0 0 3 3 3 1 Exo70 exocyst complex subunit Sec34 PF04136.15 EGG24404.1 - 0.00078 19.4 4.2 0.00078 19.4 4.2 4.0 2 1 1 3 3 3 1 Sec34-like family DUF3898 PF13037.6 EGG24404.1 - 0.027 14.6 0.2 0.088 12.9 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3898) PilM PF07419.12 EGG24404.1 - 0.055 13.6 0.0 0.21 11.8 0.0 2.0 1 0 0 1 1 1 0 PilM DASH_Dad2 PF08654.10 EGG24404.1 - 0.056 13.9 0.2 0.39 11.2 0.2 2.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 DUF948 PF06103.11 EGG24404.1 - 0.57 10.5 1.7 6.4 7.1 0.1 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Swi5 PF07061.11 EGG24404.1 - 0.95 9.6 4.6 1.9 8.6 0.6 3.3 3 0 0 3 3 3 0 Swi5 Laminin_II PF06009.12 EGG24404.1 - 2.3 8.2 8.2 0.29 11.1 0.2 3.2 3 1 1 4 4 4 0 Laminin Domain II GST_N PF02798.20 EGG24405.1 - 2.2e-18 66.4 0.3 6.6e-18 64.8 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGG24405.1 - 5.6e-16 58.7 0.0 9.4e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGG24405.1 - 1.5e-13 50.8 0.0 3.3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGG24405.1 - 9.7e-08 32.1 0.0 1.8e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG24405.1 - 0.0004 20.5 0.0 0.00074 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGG24405.1 - 0.025 14.6 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EGG24405.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Ham1p_like PF01725.16 EGG24407.1 - 4.1e-50 170.3 0.0 6e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Ham1 family Abhydrolase_1 PF00561.20 EGG24407.1 - 1.7e-24 86.9 0.2 7e-24 84.9 0.3 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG24407.1 - 1.9e-08 35.2 0.0 3.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG24407.1 - 5e-08 32.5 0.0 1.7e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 EGG24407.1 - 0.094 13.1 0.0 1.7 9.1 0.0 2.6 2 1 0 2 2 2 0 Epoxide hydrolase N terminus FSH1 PF03959.13 EGG24407.1 - 0.11 12.1 0.2 0.6 9.7 0.0 2.2 3 0 0 3 3 3 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 EGG24407.1 - 0.17 12.0 0.0 0.5 10.5 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein Sugar_tr PF00083.24 EGG24408.1 - 1e-77 261.9 34.8 3.2e-77 260.3 34.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG24408.1 - 3.6e-27 95.2 37.2 6.3e-26 91.1 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily V_ATPase_I PF01496.19 EGG24408.1 - 0.042 11.8 0.0 0.11 10.3 0.0 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Bacteriocin_IIc PF10439.9 EGG24408.1 - 0.42 10.8 7.6 1.8 8.7 2.7 3.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF3100 PF11299.8 EGG24408.1 - 3.5 7.0 13.3 0.11 11.9 2.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3100) LigB PF02900.18 EGG24409.1 - 1e-30 106.8 0.1 3.6e-30 105.0 0.1 1.7 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase LRR_4 PF12799.7 EGG24410.1 - 0.014 15.8 12.1 2.1 8.9 1.9 5.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Ribosomal_L19 PF01245.20 EGG24410.1 - 0.1 12.5 0.0 7.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L19 Clathrin_propel PF01394.20 EGG24410.1 - 0.47 10.9 0.1 0.47 10.9 0.1 3.0 4 0 0 4 4 4 0 Clathrin propeller repeat DDE_1 PF03184.19 EGG24411.1 - 4.7e-09 36.1 0.7 4.7e-09 36.1 0.7 2.0 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EGG24411.1 - 4.2e-06 26.7 0.8 1.1e-05 25.4 0.8 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain RNA_pol_Rpb5_C PF01191.19 EGG24411.1 - 0.009 15.9 1.2 0.015 15.1 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain DUF2603 PF10788.9 EGG24411.1 - 0.038 14.0 1.6 0.099 12.7 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) Y_Y_Y PF07495.13 EGG24412.1 - 0.00022 21.1 3.0 1.1 9.3 0.0 4.4 4 0 0 4 4 4 2 Y_Y_Y domain CarboxypepD_reg PF13620.6 EGG24412.1 - 0.0062 16.8 9.2 2.7 8.3 0.1 6.3 7 0 0 7 7 7 2 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 EGG24412.1 - 0.69 10.2 6.9 1.5 9.1 0.1 4.3 5 0 0 5 5 5 0 SdrD B-like domain FlgD_ig PF13860.6 EGG24412.1 - 1.5 8.7 4.2 67 3.4 0.2 4.4 4 1 0 4 4 4 0 FlgD Ig-like domain tRNA-synt_2b PF00587.25 EGG24413.1 - 7.2e-32 110.8 0.0 5.1e-31 108.0 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGG24413.1 - 2.4e-20 72.4 0.7 7.6e-20 70.9 0.3 2.0 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.21 EGG24413.1 - 2.3e-06 27.5 0.0 7.3e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 TGS domain RgpF PF05045.12 EGG24413.1 - 0.0016 17.3 1.6 0.0031 16.4 1.6 1.4 1 0 0 1 1 1 1 Rhamnan synthesis protein F Macoilin PF09726.9 EGG24413.1 - 1.3 7.5 6.7 2.1 6.8 6.7 1.4 1 0 0 1 1 1 0 Macoilin family DUF3088 PF11287.8 EGG24414.1 - 0.11 12.3 0.1 0.3 10.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) DUF5614 PF18474.1 EGG24414.1 - 0.12 11.6 0.2 0.24 10.7 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5614) TFIID_20kDa PF03847.13 EGG24415.1 - 1.8e-30 105.2 0.7 3.1e-30 104.4 0.7 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EGG24415.1 - 0.0014 18.9 0.2 0.0027 17.9 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGG24415.1 - 0.0023 18.0 0.8 0.005 16.9 0.5 1.8 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF4192 PF13830.6 EGG24415.1 - 3.9 7.4 11.5 0.12 12.4 4.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Roughex PF06020.11 EGG24415.1 - 6.8 5.7 16.0 1.6 7.7 7.1 2.2 2 0 0 2 2 2 0 Drosophila roughex protein DUF2967 PF11179.8 EGG24416.1 - 0.83 7.7 8.0 1.1 7.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) SUIM_assoc PF16619.5 EGG24416.1 - 2.3 8.3 13.2 4.4 7.4 13.2 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 IBN_N PF03810.19 EGG24417.1 - 5.9e-11 42.1 1.1 1.8e-10 40.6 0.4 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.22 EGG24417.1 - 0.001 19.1 0.0 1.3 9.4 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat Xpo1 PF08389.12 EGG24417.1 - 0.0016 18.6 0.1 0.016 15.2 0.1 2.9 1 1 0 1 1 1 1 Exportin 1-like protein HEAT_EZ PF13513.6 EGG24417.1 - 0.03 14.8 0.9 9.4 6.9 0.0 4.5 5 0 0 5 5 5 0 HEAT-like repeat HEAT_2 PF13646.6 EGG24417.1 - 0.18 12.2 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 HEAT repeats BUD22 PF09073.10 EGG24417.1 - 5.9 6.1 13.1 9.1 5.5 13.1 1.2 1 0 0 1 1 1 0 BUD22 Dicty_spore_N PF04562.12 EGG24419.1 - 4.8e-19 69.1 20.5 2e-17 63.9 20.5 4.2 1 0 0 1 1 1 1 Dictyostelium spore coat protein, N terminus Sod_Cu PF00080.20 EGG24420.1 - 3.3e-14 53.2 3.1 3.3e-14 53.2 3.1 1.7 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 EGG24420.1 - 0.025 15.0 1.1 0.04 14.3 0.2 1.7 2 0 0 2 2 2 0 Heavy-metal-associated domain PTEN_C2 PF10409.9 EGG24421.1 - 3.6e-15 55.9 8.5 1.7e-14 53.7 0.2 2.9 3 0 0 3 3 3 2 C2 domain of PTEN tumour-suppressor protein RXT2_N PF08595.11 EGG24421.1 - 3.6 7.6 26.7 3.9 7.5 2.7 4.4 4 0 0 4 4 4 0 RXT2-like, N-terminal Presenilin PF01080.17 EGG24421.1 - 4.4 6.0 32.8 0.41 9.4 7.3 3.1 3 0 0 3 3 3 0 Presenilin ACOX PF01756.19 EGG24423.1 - 4.7e-34 117.5 0.0 1.1e-33 116.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGG24423.1 - 1e-20 73.7 0.0 1.8e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGG24423.1 - 1.8e-06 28.3 0.1 4.5e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SMC_N PF02463.19 EGG24424.1 - 3.5e-52 177.0 34.9 3.3e-51 173.8 34.9 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGG24424.1 - 1.3e-21 77.0 0.0 4.2e-21 75.4 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EGG24424.1 - 3.1e-19 70.3 2.1 3.1e-19 70.3 2.1 8.2 5 2 3 8 8 8 1 AAA domain AAA_21 PF13304.6 EGG24424.1 - 2.2e-14 54.0 4.8 1e-08 35.3 0.1 3.9 4 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system GATA PF00320.27 EGG24424.1 - 1.4e-12 47.0 9.1 2.9e-12 46.0 9.1 1.6 1 0 0 1 1 1 1 GATA zinc finger AAA_15 PF13175.6 EGG24424.1 - 0.00045 20.0 31.5 0.00045 20.0 31.5 6.5 5 2 0 5 5 5 1 AAA ATPase domain AAA_29 PF13555.6 EGG24424.1 - 0.0028 17.3 0.0 0.0071 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EGG24424.1 - 0.063 13.8 0.1 0.063 13.8 0.1 7.4 5 3 1 6 6 6 0 ABC transporter DUF3040 PF11239.8 EGG24424.1 - 3 8.2 4.8 1.2 9.4 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Acetyltransf_1 PF00583.25 EGG24426.1 - 8.8e-15 55.0 0.0 1.4e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG24426.1 - 7.3e-09 35.9 0.4 1.7e-08 34.8 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGG24426.1 - 5.6e-08 32.8 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG24426.1 - 6e-07 29.3 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein DUF4805 PF16063.5 EGG24426.1 - 0.00041 19.8 0.2 0.00062 19.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4805) Acetyltransf_9 PF13527.7 EGG24426.1 - 0.0055 16.8 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGG24426.1 - 0.037 13.7 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EGG24426.1 - 0.12 12.6 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mucin PF01456.17 EGG24426.1 - 0.44 10.5 9.7 0.28 11.2 4.4 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Med13_C PF06333.12 EGG24426.1 - 2.2 7.4 7.2 0.12 11.7 1.1 1.9 2 1 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain DUF4834 PF16118.5 EGG24426.1 - 7.3 7.6 18.6 4.3 8.4 3.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) PH PF00169.29 EGG24427.1 - 2.5e-06 27.9 2.1 2.5e-05 24.7 0.3 2.0 1 1 1 2 2 2 1 PH domain DUF1319 PF07028.11 EGG24427.1 - 0.026 14.7 0.1 0.034 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) PH PF00169.29 EGG24428.1 - 5.5e-15 55.8 0.1 1.8e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EGG24428.1 - 0.0004 20.8 0.2 0.0004 20.8 0.2 3.0 3 1 0 3 3 3 1 Pleckstrin homology domain PepSY_2 PF13670.6 EGG24428.1 - 0.0019 18.2 0.9 0.0019 18.2 0.9 1.6 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain PH_6 PF15406.6 EGG24428.1 - 0.01 16.1 0.1 6.1 7.2 0.1 2.8 1 1 1 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 EGG24428.1 - 0.063 13.6 0.0 0.51 10.7 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain SOBP PF15279.6 EGG24428.1 - 9.5 6.7 17.6 14 6.2 17.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF1899 PF08953.11 EGG24429.1 - 6.4e-42 141.3 2.5 5.2e-21 74.3 0.2 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EGG24429.1 - 1.4e-32 111.3 0.6 3e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 Type of WD40 repeat WD40 PF00400.32 EGG24429.1 - 1.9e-25 88.6 9.6 0.00015 22.4 0.1 9.0 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG24429.1 - 1.3e-08 35.0 0.1 0.011 16.0 0.0 5.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG24429.1 - 0.0062 15.2 1.8 0.4 9.3 0.2 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 SapB_1 PF05184.15 EGG24430.1 - 3.7e-44 148.2 27.6 2.2e-13 49.9 1.1 6.5 7 0 0 7 7 7 4 Saposin-like type B, region 1 SapB_2 PF03489.17 EGG24430.1 - 7.5e-40 134.7 30.3 2.1e-11 43.7 1.1 5.3 5 0 0 5 5 5 4 Saposin-like type B, region 2 ARL2_Bind_BART PF11527.8 EGG24430.1 - 4.5e-05 23.5 1.9 1.5 8.9 0.0 3.7 3 1 0 3 3 3 3 The ARF-like 2 binding protein BART DUF5069 PF16798.5 EGG24430.1 - 0.038 14.2 0.2 0.21 11.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) Phage_holin_3_1 PF05106.12 EGG24430.1 - 0.11 13.0 2.3 17 6.0 0.0 3.2 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) ABC_tran PF00005.27 EGG24431.1 - 1.5e-27 96.8 0.1 3.5e-27 95.6 0.1 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGG24431.1 - 6.9e-25 87.9 34.3 6.9e-25 87.9 34.3 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGG24431.1 - 8.9e-07 29.0 0.6 0.00039 20.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG24431.1 - 0.0016 17.9 0.4 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 EGG24431.1 - 0.0039 16.6 21.8 0.0039 16.6 21.8 2.7 2 1 1 3 3 3 1 ABC-2 type transporter AAA_29 PF13555.6 EGG24431.1 - 0.026 14.2 0.3 0.062 13.1 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MukB PF04310.12 EGG24431.1 - 0.04 13.7 0.3 0.11 12.3 0.1 1.7 2 0 0 2 2 2 0 MukB N-terminal SH3_9 PF14604.6 EGG24432.1 - 2.3e-17 62.6 0.5 3.6e-17 61.9 0.5 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGG24432.1 - 1.3e-15 56.7 0.1 2.4e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 EGG24432.1 - 3.4e-14 52.9 0.1 3.4e-14 52.9 0.1 2.8 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 EGG24432.1 - 1.2e-12 47.4 0.0 2.1e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 EGG24432.1 - 0.0065 16.0 7.8 0.0065 16.0 7.8 2.1 1 1 1 2 2 2 1 Vps5 C terminal like TPR_MLP1_2 PF07926.12 EGG24432.1 - 2.2 8.4 22.8 1.2 9.2 16.9 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 EGG24432.1 - 2.5 7.4 7.9 3.8 6.8 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ApoO PF09769.9 EGG24432.1 - 2.5 8.1 8.0 4.2 7.4 3.6 2.7 1 1 1 2 2 2 0 Apolipoprotein O GPI2 PF06432.11 EGG24433.1 - 6.2e-73 245.7 17.5 2.6e-71 240.3 17.5 2.4 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase RhoGAP PF00620.27 EGG24433.1 - 2.4e-24 85.9 0.1 5.1e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain DAO PF01266.24 EGG24434.1 - 3.9e-52 178.0 0.0 5.4e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EGG24434.1 - 1.9e-38 131.2 0.1 3.6e-38 130.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EGG24434.1 - 3.7e-05 23.0 1.7 0.0065 15.6 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 EGG24434.1 - 0.00011 21.7 2.2 0.031 13.6 0.5 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGG24434.1 - 0.00013 22.1 0.7 0.018 15.3 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG24434.1 - 0.00054 19.3 0.0 0.0014 18.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGG24434.1 - 0.00058 19.0 0.8 0.023 13.8 0.2 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 EGG24434.1 - 0.021 14.7 0.0 0.021 14.7 0.0 2.4 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TFIIA PF03153.13 EGG24434.1 - 0.028 14.4 7.5 0.041 13.9 7.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5061 PF16587.5 EGG24434.1 - 0.04 14.0 0.2 0.094 12.8 0.2 1.6 1 0 0 1 1 1 0 17 kDa common-antigen outer membrane protein Methyltransf_34 PF11312.8 EGG24434.1 - 0.045 13.0 0.1 0.073 12.3 0.1 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Pyr_redox PF00070.27 EGG24434.1 - 0.079 13.5 0.1 0.22 12.1 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG24434.1 - 0.097 11.9 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YajC PF02699.15 EGG24434.1 - 0.74 9.7 3.4 1.4 8.9 2.4 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit SUIM_assoc PF16619.5 EGG24434.1 - 2.6 8.2 13.9 8.4 6.5 13.9 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SAM_MT PF04445.13 EGG24435.1 - 3.2e-37 128.2 0.0 5.5e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase FNIP PF05725.12 EGG24436.1 - 4.4e-37 126.0 24.8 9e-12 45.0 1.6 8.5 4 2 3 7 7 7 7 FNIP Repeat RhoGAP PF00620.27 EGG24436.1 - 8.3e-18 64.7 0.1 2.6e-17 63.0 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain FERM_f0 PF16511.5 EGG24436.1 - 3.5e-14 52.9 8.1 1.8e-13 50.6 0.1 4.3 5 0 0 5 5 5 1 N-terminal or F0 domain of Talin-head FERM E1-E2_ATPase PF00122.20 EGG24437.1 - 6e-36 123.7 0.5 6e-36 123.7 0.5 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 EGG24437.1 - 3.4e-17 61.9 0.0 7.7e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EGG24437.1 - 1e-15 58.6 1.1 3.5e-15 56.9 1.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EGG24437.1 - 3e-14 53.1 8.4 3e-14 53.1 8.4 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGG24437.1 - 1e-08 35.1 0.0 2.3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 EGG24437.1 - 4.7e-06 27.1 0.0 0.0078 16.6 0.0 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGG24437.1 - 0.00049 19.9 1.7 0.041 13.6 0.3 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2768 PF10966.8 EGG24437.1 - 3.2 8.3 6.0 0.42 11.1 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) Hydrolase_6 PF13344.6 EGG24438.1 - 0.33 11.1 2.9 8.5 6.6 0.2 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Glyco_tran_WbsX PF14307.6 EGG24438.1 - 0.64 9.4 6.6 0.21 11.0 3.8 1.4 1 1 0 1 1 1 0 Glycosyltransferase WbsX DUF572 PF04502.13 EGG24438.1 - 1.9 8.0 24.5 2.4 7.7 24.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-met PF12874.7 EGG24439.1 - 2.4e-09 37.3 14.3 5e-05 23.5 2.2 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGG24439.1 - 1.5e-06 28.4 16.9 0.00017 21.8 3.9 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGG24439.1 - 1.8e-05 25.0 15.6 0.0022 18.3 7.1 2.5 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EGG24439.1 - 0.17 12.4 13.3 1.6 9.3 1.5 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGG24439.1 - 8.7 7.5 10.3 12 7.0 1.4 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger MutS_V PF00488.21 EGG24440.1 - 3.7e-61 206.4 0.6 6.5e-61 205.7 0.6 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGG24440.1 - 2.3e-27 96.4 3.6 3.4e-27 95.9 2.5 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EGG24440.1 - 2.4e-06 27.8 0.2 6.2e-06 26.5 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EGG24440.1 - 7.8e-06 26.2 0.0 1.9e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain II AAA_30 PF13604.6 EGG24440.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGG24440.1 - 0.029 14.4 0.3 0.22 11.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGG24440.1 - 0.085 12.8 0.3 0.76 9.6 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 EGG24440.1 - 0.18 12.3 0.0 0.18 12.3 0.0 3.0 3 1 0 3 3 3 0 AAA domain Pkinase PF00069.25 EGG24441.1 - 3.9e-75 252.6 0.0 3.9e-75 252.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG24441.1 - 9.8e-35 120.1 0.0 1.9e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG24441.1 - 1.2e-06 28.1 0.0 3.1e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like POR PF01558.18 EGG24441.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF2098 PF09871.9 EGG24441.1 - 2.8 8.4 8.2 2.9 8.3 0.0 3.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) DSPc PF00782.20 EGG24442.1 - 7.9e-07 29.0 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGG24442.1 - 0.0043 17.1 0.0 0.006 16.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGG24442.1 - 0.0049 16.5 0.0 0.0067 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DDRGK PF09756.9 EGG24443.1 - 4.4e-57 192.7 36.2 4.4e-57 192.7 36.2 2.1 2 0 0 2 2 2 2 DDRGK domain FeoC PF09012.10 EGG24443.1 - 0.0076 16.3 0.1 3.2 7.9 0.0 2.5 2 0 0 2 2 2 2 FeoC like transcriptional regulator Ndc1_Nup PF09531.10 EGG24443.1 - 1.2 7.7 10.7 1.4 7.5 10.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2981 PF11200.8 EGG24443.1 - 2.3 7.9 9.6 3.5 7.3 9.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) GST_N_3 PF13417.6 EGG24444.1 - 6.9e-16 58.4 0.1 1.1e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGG24444.1 - 2.1e-15 56.8 0.1 3.9e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGG24444.1 - 2.9e-13 49.9 0.0 5.9e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGG24444.1 - 6.5e-06 26.3 0.0 1.5e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGG24444.1 - 0.0075 16.5 0.1 0.019 15.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EGG24444.1 - 0.021 15.1 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin HAD_SAK_2 PF18143.1 EGG24444.1 - 0.11 12.8 0.1 8.3 6.7 0.0 2.1 1 1 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins GST_C_2 PF13410.6 EGG24444.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SART-1 PF03343.13 EGG24445.1 - 3.6e-71 240.6 98.7 1.4e-57 195.7 89.0 2.0 1 1 1 2 2 2 2 SART-1 family Chorion_3 PF05387.11 EGG24445.1 - 3.3 7.3 9.2 9.1 5.8 9.2 1.7 1 0 0 1 1 1 0 Chorion family 3 ORC2 PF04084.14 EGG24446.1 - 8.1e-110 366.8 10.0 1.7e-109 365.8 10.0 1.5 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Pox_Ag35 PF03286.14 EGG24446.1 - 0.0056 16.5 25.1 0.12 12.1 0.2 3.2 3 0 0 3 3 3 3 Pox virus Ag35 surface protein DUF5320 PF17253.2 EGG24446.1 - 0.085 13.9 0.9 0.26 12.4 0.9 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5320) RbsD_FucU PF05025.13 EGG24446.1 - 0.84 10.1 4.0 11 6.5 0.4 2.8 3 0 0 3 3 3 0 RbsD / FucU transport protein family DUF3439 PF11921.8 EGG24446.1 - 2 8.4 6.9 0.38 10.7 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RPA43_OB PF17875.1 EGG24446.1 - 2.9 8.5 12.3 9.8 6.8 0.1 3.3 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I FAM176 PF14851.6 EGG24446.1 - 3.6 7.2 22.8 6.7 6.4 1.3 3.2 3 0 0 3 3 3 0 FAM176 family DUF4611 PF15387.6 EGG24446.1 - 5.6 7.2 20.3 1.6 9.0 0.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF1943 PF09172.11 EGG24447.1 - 0.01 15.1 4.2 0.015 14.6 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) PRKCSH_1 PF13015.6 EGG24447.1 - 0.011 15.4 0.8 0.022 14.5 0.8 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein TMEM70 PF06979.12 EGG24447.1 - 0.075 13.4 0.2 0.17 12.3 0.2 1.6 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex DUF1848 PF08902.11 EGG24447.1 - 0.16 11.7 1.7 0.23 11.2 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Vma12 PF11712.8 EGG24447.1 - 4.2 7.5 7.4 0.28 11.2 2.2 1.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SH3_1 PF00018.28 EGG24448.1 - 2.3e-16 59.1 0.3 4.2e-16 58.3 0.3 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGG24448.1 - 2.1e-13 49.9 0.2 3.9e-13 49.0 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGG24448.1 - 4.5e-11 42.3 0.0 8.9e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M1 PF01433.20 EGG24449.1 - 3.7e-76 255.5 0.8 7e-76 254.6 0.8 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGG24449.1 - 4e-67 227.0 0.1 1.6e-66 225.0 0.1 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGG24449.1 - 5e-55 186.6 3.4 5e-55 186.6 3.4 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain SprT-like PF10263.9 EGG24449.1 - 0.13 12.1 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 SprT-like family Orn_Arg_deC_N PF02784.16 EGG24450.1 - 8.8e-31 107.1 0.0 1.3e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGG24450.1 - 3e-20 72.3 0.0 3.4e-20 72.1 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 EGG24450.1 - 0.00057 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain WD40 PF00400.32 EGG24451.1 - 3e-65 214.6 24.0 3.2e-09 37.2 0.6 9.2 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG24451.1 - 6.4e-26 90.5 2.8 7.8e-05 22.9 0.0 6.5 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EGG24451.1 - 4.6e-17 62.3 1.3 8.8e-17 61.4 1.3 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 EGG24451.1 - 1.1e-10 41.7 0.3 0.011 15.7 0.0 4.2 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGG24451.1 - 2e-10 40.2 0.2 0.079 11.9 0.0 5.1 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGG24451.1 - 1.1e-07 30.9 2.6 0.36 9.4 0.0 4.7 4 2 1 6 6 6 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 EGG24451.1 - 3e-07 30.1 0.6 0.049 12.9 0.0 4.7 3 2 2 5 5 5 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EGG24451.1 - 0.00094 18.6 0.0 6.8 5.9 0.0 3.8 3 1 0 3 3 3 2 WD40-like domain PD40 PF07676.12 EGG24451.1 - 0.001 18.9 9.5 0.41 10.7 0.0 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EGG24451.1 - 0.0012 17.5 0.0 0.059 11.9 0.0 2.7 2 1 1 3 3 3 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 EGG24451.1 - 0.05 12.7 0.0 0.48 9.4 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region Hira PF07569.11 EGG24451.1 - 0.098 12.4 0.6 50 3.5 0.0 3.4 3 0 0 3 3 3 0 TUP1-like enhancer of split Aldolase_II PF00596.21 EGG24454.1 - 3.4e-41 141.2 0.0 4e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DAO PF01266.24 EGG24455.1 - 3.9e-34 118.8 0.0 4.6e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase CpXC PF14353.6 EGG24455.1 - 0.032 14.3 0.3 0.077 13.0 0.3 1.7 1 0 0 1 1 1 0 CpXC protein Thi4 PF01946.17 EGG24455.1 - 0.039 13.2 0.1 0.077 12.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 EGG24455.1 - 0.052 13.8 0.2 0.2 11.9 0.2 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGG24455.1 - 0.12 11.5 0.2 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SUIM_assoc PF16619.5 EGG24455.1 - 0.22 11.6 9.1 0.48 10.5 9.1 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 E_Pc_C PF06752.12 EGG24455.1 - 1.6 8.8 10.6 0.073 13.2 3.7 1.9 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Androgen_recep PF02166.16 EGG24455.1 - 3 6.6 6.5 4.6 6.0 6.5 1.2 1 0 0 1 1 1 0 Androgen receptor NPL PF17800.1 EGG24456.1 - 1.2e-08 35.4 0.1 1.2e-08 35.4 0.1 2.1 1 1 1 2 2 2 1 Nucleoplasmin-like domain YL1 PF05764.13 EGG24456.1 - 0.0017 18.5 15.0 0.002 18.3 15.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 EGG24456.1 - 0.03 12.6 8.5 0.033 12.5 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CCDC53 PF10152.9 EGG24456.1 - 1 9.8 14.8 1.6 9.1 14.8 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Suf PF05843.14 EGG24456.1 - 1.3 8.9 19.5 1.9 8.4 19.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 EGG24456.1 - 3.2 8.4 21.9 4.8 7.8 21.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med3 PF11593.8 EGG24456.1 - 4.8 6.3 24.6 6.7 5.8 24.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MCM PF00493.23 EGG24457.1 - 4.2e-104 346.5 0.1 7.3e-104 345.7 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGG24457.1 - 9e-37 125.7 0.1 1.8e-36 124.8 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGG24457.1 - 2.6e-25 88.7 0.8 7.1e-25 87.3 0.8 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGG24457.1 - 2.5e-14 53.7 4.7 2.5e-14 53.7 4.7 2.8 2 1 0 2 2 2 1 MCM N-terminal domain MCM6_C PF18263.1 EGG24457.1 - 1.7e-12 47.5 0.4 1.7e-12 47.5 0.4 3.3 3 0 0 3 3 3 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 EGG24457.1 - 2.8e-08 33.4 0.0 6.1e-07 29.0 0.0 2.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGG24457.1 - 6.7e-05 22.8 0.0 0.00027 20.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGG24457.1 - 0.00014 21.9 0.0 0.00056 19.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGG24457.1 - 0.0033 17.1 0.0 0.009 15.7 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain Peptidase_S9_N PF02897.15 EGG24459.1 - 2.1e-101 339.7 11.8 2.9e-101 339.3 11.8 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EGG24459.1 - 1.7e-48 164.9 0.0 3.3e-48 164.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4811 PF16069.5 EGG24459.1 - 0.61 9.9 5.8 0.11 12.4 1.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4811) LCM PF04072.14 EGG24460.1 - 2.7e-22 79.6 0.0 1.8e-21 76.9 0.0 2.1 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Methyltransf_32 PF13679.6 EGG24460.1 - 0.056 13.4 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Complex1_LYR PF05347.15 EGG24461.1 - 3.8e-08 33.2 1.6 1.3e-07 31.6 1.6 1.9 1 0 0 1 1 1 1 Complex 1 protein (LYR family) YjbF PF11102.8 EGG24461.1 - 0.075 12.8 1.5 0.97 9.2 0.5 2.7 3 0 0 3 3 3 0 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF Nse4_C PF08743.10 EGG24462.1 - 7.7e-19 67.7 0.1 7.7e-19 67.7 0.1 2.4 3 0 0 3 3 3 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EGG24462.1 - 6.1e-13 48.7 2.6 1.6e-12 47.3 2.6 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE MatP_C PF17414.2 EGG24462.1 - 0.14 12.3 2.9 0.71 10.1 0.0 2.9 3 0 0 3 3 3 0 MatP C-terminal ribbon-helix-helix domain HABP4_PAI-RBP1 PF04774.15 EGG24462.1 - 0.29 12.0 10.0 0.44 11.4 1.4 3.1 2 1 0 2 2 2 0 Hyaluronan / mRNA binding family DUF4539 PF15072.6 EGG24463.1 - 5.4e-24 84.0 0.1 8.6e-24 83.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) TPR_2 PF07719.17 EGG24464.1 - 4.9e-27 91.8 8.2 1.9e-05 24.4 0.0 10.8 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGG24464.1 - 4e-26 89.7 16.1 3.5e-06 26.6 0.0 11.6 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGG24464.1 - 4.3e-19 67.1 15.2 1.8e-05 24.6 0.0 10.8 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGG24464.1 - 4.3e-15 56.0 6.2 0.034 14.7 0.4 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGG24464.1 - 1.7e-14 53.3 2.9 0.036 14.9 0.1 6.9 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGG24464.1 - 4.1e-12 45.6 19.8 0.0024 17.5 0.0 9.4 8 3 3 11 11 11 4 TPR repeat TPR_16 PF13432.6 EGG24464.1 - 6.1e-10 39.6 0.0 0.00075 20.1 0.7 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGG24464.1 - 1.2e-09 37.8 6.9 0.41 11.2 0.0 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGG24464.1 - 1.6e-09 37.9 18.9 0.00093 19.4 0.2 7.1 5 4 4 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGG24464.1 - 2e-09 37.4 0.3 2.5 8.3 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG24464.1 - 2.6e-09 37.2 13.2 0.16 12.3 0.7 9.5 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG24464.1 - 5.3e-08 32.4 0.9 0.38 10.9 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGG24464.1 - 5e-07 29.9 2.9 2.4 9.0 0.1 6.5 8 0 0 8 8 7 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGG24464.1 - 0.01 15.5 0.1 1.5 8.5 0.0 2.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 EGG24464.1 - 0.031 14.1 0.1 39 4.3 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Patatin PF01734.22 EGG24465.1 - 2.3e-17 63.9 0.0 1.8e-15 57.7 0.0 2.6 2 0 0 2 2 2 1 Patatin-like phospholipase PH PF00169.29 EGG24465.1 - 1.2e-08 35.4 7.8 2.8e-08 34.2 7.8 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGG24465.1 - 0.00075 19.9 7.1 0.00075 19.9 7.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Hamartin PF04388.12 EGG24465.1 - 0.47 9.1 13.4 1.6 7.3 13.4 2.0 1 0 0 1 1 1 0 Hamartin protein Phage_integrase PF00589.22 EGG24466.1 - 3.3e-09 36.8 0.0 4.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family DBC1 PF14443.6 EGG24467.1 - 3e-41 140.3 1.2 5.1e-41 139.5 0.1 2.0 1 1 1 2 2 2 1 DBC1 DUF3439 PF11921.8 EGG24467.1 - 0.022 14.7 2.9 0.07 13.1 2.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LAP1C PF05609.12 EGG24467.1 - 0.96 8.5 38.7 0.14 11.2 8.8 3.4 3 0 0 3 3 3 0 Lamina-associated polypeptide 1C (LAP1C) NARP1 PF12569.8 EGG24467.1 - 8 5.2 10.4 2.6 6.9 5.4 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Aminotran_1_2 PF00155.21 EGG24468.1 - 5.1e-35 121.3 0.0 1.1e-34 120.2 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II LRR_4 PF12799.7 EGG24469.1 - 7.2e-09 35.8 24.7 0.046 14.2 0.1 7.2 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG24469.1 - 0.00023 20.9 0.1 0.00023 20.9 0.1 6.0 4 2 1 6 6 6 1 Leucine rich repeat LRR_6 PF13516.6 EGG24469.1 - 0.0007 19.5 3.2 3.8 7.8 0.1 5.5 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 EGG24469.1 - 0.0041 17.5 17.2 4.4 8.2 0.2 7.7 7 2 0 7 7 7 2 Leucine Rich Repeat DUF2058 PF09831.9 EGG24469.1 - 0.052 13.7 0.3 0.052 13.7 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) GST_C_6 PF17171.4 EGG24469.1 - 0.097 12.5 0.1 4.3 7.2 0.0 3.6 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain CDK5_activator PF03261.15 EGG24469.1 - 0.15 11.6 24.9 0.072 12.6 11.0 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein DUF1616 PF07760.11 EGG24469.1 - 0.61 9.4 4.7 1.1 8.5 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1616) Med15 PF09606.10 EGG24469.1 - 2.6 6.6 44.4 3.5 6.2 44.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SWI-SNF_Ssr4 PF08549.10 EGG24469.1 - 7 5.1 19.9 11 4.5 19.9 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Sel1 PF08238.12 EGG24470.1 - 2.2e-45 152.0 35.2 6e-06 26.8 0.3 11.4 11 0 0 11 11 11 10 Sel1 repeat Spore_Cse60 PF10957.8 EGG24470.1 - 0.0018 18.3 1.3 0.24 11.4 0.0 3.1 2 0 0 2 2 2 1 Sporulation protein Cse60 PepSY_TM_like_2 PF16357.5 EGG24470.1 - 0.7 9.8 2.6 2 8.3 2.6 1.8 1 0 0 1 1 1 0 Putative PepSY_TM-like DUF3439 PF11921.8 EGG24470.1 - 1.4 8.9 4.0 2.9 7.9 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) WBP-1 PF11669.8 EGG24470.1 - 3.7 8.2 7.4 12 6.6 1.6 3.4 3 1 0 3 3 3 0 WW domain-binding protein 1 SID-1_RNA_chan PF13965.6 EGG24470.1 - 9.2 4.5 15.8 0.87 7.9 8.4 2.6 3 0 0 3 3 3 0 dsRNA-gated channel SID-1 C2 PF00168.30 EGG24471.1 - 1e-16 61.1 0.3 2.3e-16 59.9 0.3 1.6 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 EGG24471.1 - 3.3e-06 27.3 6.6 0.00053 20.2 0.2 4.0 3 1 1 4 4 4 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 EGG24471.1 - 0.0034 16.0 0.0 0.0034 16.0 0.0 2.9 2 1 1 3 3 3 1 Plant family of unknown function (DUF810) TPPII_N PF12583.8 EGG24471.1 - 0.22 12.1 0.1 0.22 12.1 0.1 2.5 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal G-alpha PF00503.20 EGG24473.1 - 2.7e-99 332.7 12.1 3.6e-99 332.3 12.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGG24473.1 - 7.4e-15 54.8 2.2 4.5e-10 39.3 0.2 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG24473.1 - 5.5e-05 22.8 2.0 0.0007 19.2 0.5 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGG24473.1 - 0.00012 21.5 5.8 0.0014 18.0 0.4 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGG24473.1 - 0.0017 18.5 0.3 2.1 8.6 0.1 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arteri_env PF01606.16 EGG24473.1 - 0.007 16.3 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Arterivirus envelope protein AAA_29 PF13555.6 EGG24473.1 - 0.079 12.7 0.3 0.32 10.7 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ras PF00071.22 EGG24473.1 - 0.23 11.1 3.5 6.6 6.3 0.3 3.1 3 0 0 3 3 3 0 Ras family GATase PF00117.28 EGG24474.1 - 7.1e-11 42.2 0.0 1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGG24474.1 - 7.5e-06 25.9 0.1 1.2e-05 25.2 0.1 1.4 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 EGG24474.1 - 0.01 15.4 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain 30K_MP_core PF17644.1 EGG24474.1 - 0.065 13.1 0.1 0.8 9.6 0.0 2.3 2 0 0 2 2 2 0 Core domain of 30K viral movement proteins DJ-1_PfpI PF01965.24 EGG24474.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family ABC_membrane PF00664.23 EGG24476.1 - 1.2e-28 100.6 26.1 2.9e-28 99.3 25.6 1.9 1 1 1 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGG24476.1 - 1.7e-12 48.0 0.0 1.7e-12 48.0 0.0 2.3 2 1 0 2 2 2 1 ABC transporter Stevor PF17410.2 EGG24476.1 - 2.8 7.4 13.8 0.48 9.9 5.4 2.4 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame CDC45 PF02724.14 EGG24476.1 - 3.6 5.8 9.1 5.5 5.2 9.1 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4131 PF13567.6 EGG24476.1 - 4 7.1 8.1 0.64 9.7 0.2 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) CAC1F_C PF16885.5 EGG24476.1 - 8 6.0 7.5 12 5.4 7.5 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Methyltransf_11 PF08241.12 EGG24477.1 - 1.3e-11 45.0 0.0 2.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG24477.1 - 1.7e-11 44.7 0.2 7.2e-11 42.7 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGG24477.1 - 2.4e-06 27.5 0.0 3.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG24477.1 - 1.4e-05 25.7 0.2 5.7e-05 23.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG24477.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGG24477.1 - 0.0025 17.1 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase N6_N4_Mtase PF01555.18 EGG24477.1 - 0.0027 17.4 0.0 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 DNA methylase Methyltransf_31 PF13847.6 EGG24477.1 - 0.0044 16.8 0.1 0.0071 16.1 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EGG24477.1 - 0.022 15.1 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 EGG24477.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 EGG24477.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EGG24477.1 - 0.098 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ras PF00071.22 EGG24478.1 - 1.5e-39 135.2 4.6 5.7e-24 84.5 0.2 2.4 2 0 0 2 2 2 2 Ras family PH PF00169.29 EGG24478.1 - 1.6e-11 44.6 2.3 2.8e-11 43.9 0.8 2.2 2 0 0 2 2 2 1 PH domain Roc PF08477.13 EGG24478.1 - 3.5e-11 43.4 1.4 5.8e-06 26.5 0.0 3.2 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase PH_6 PF15406.6 EGG24478.1 - 1.1e-05 25.7 0.1 3.9e-05 23.9 0.1 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain MCM PF00493.23 EGG24478.1 - 0.0046 16.1 0.1 0.78 8.8 0.0 2.4 2 0 0 2 2 2 2 MCM P-loop domain PH_4 PF15404.6 EGG24478.1 - 0.077 12.8 0.1 0.077 12.8 0.1 3.4 3 0 0 3 3 3 0 Pleckstrin homology domain TMEM189_B_dmain PF10520.9 EGG24479.1 - 1.1e-64 217.7 0.7 1.1e-64 217.7 0.7 1.7 2 1 0 2 2 2 1 B domain of TMEM189, localisation domain XAP5 PF04921.14 EGG24479.1 - 0.0021 17.9 1.4 0.003 17.5 1.4 1.1 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF2370 PF10176.9 EGG24479.1 - 0.15 11.7 2.6 0.23 11.1 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Ctr PF04145.15 EGG24479.1 - 0.29 11.7 3.2 0.13 12.8 0.5 1.8 2 0 0 2 2 2 0 Ctr copper transporter family Menin PF05053.13 EGG24479.1 - 0.56 8.5 4.3 0.72 8.1 4.3 1.1 1 0 0 1 1 1 0 Menin Apc15p PF05841.11 EGG24479.1 - 2.7 8.8 10.9 4.4 8.1 10.9 1.2 1 0 0 1 1 1 0 Apc15p protein Prenyltrans PF00432.21 EGG24480.1 - 5.1e-21 74.1 8.6 0.0001 22.0 0.2 6.2 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat WD40 PF00400.32 EGG24481.1 - 1.4e-42 142.8 30.4 1.4e-06 28.9 0.8 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG24481.1 - 4.5e-15 55.7 14.1 0.0075 16.5 0.1 6.6 1 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGG24481.1 - 0.00019 20.6 12.6 0.00051 19.2 0.5 3.4 2 1 2 4 4 4 2 Coatomer WD associated region Nbas_N PF15492.6 EGG24481.1 - 0.0019 17.6 2.5 0.099 11.9 0.0 3.7 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EGG24481.1 - 0.084 12.8 0.3 0.26 11.3 0.3 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat DUF2387 PF09526.10 EGG24481.1 - 5.6 7.2 5.3 4 7.6 0.1 3.2 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) Methyltransf_PK PF05891.12 EGG24482.1 - 6.5e-66 222.0 0.4 9.7e-66 221.4 0.4 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 EGG24482.1 - 1.1e-06 28.6 0.1 1.5e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG24482.1 - 7e-06 26.7 0.0 2.2e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG24482.1 - 1e-05 26.2 0.0 2.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG24482.1 - 0.00033 21.3 0.0 0.001 19.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGG24482.1 - 0.018 14.4 0.1 0.036 13.4 0.1 1.5 1 0 0 1 1 1 0 O-methyltransferase domain AAA_23 PF13476.6 EGG24483.1 - 0.0011 19.5 17.1 0.0011 19.5 17.1 5.1 4 2 0 4 4 4 1 AAA domain cwf21 PF08312.12 EGG24483.1 - 0.12 12.6 4.7 0.33 11.1 4.7 1.8 1 0 0 1 1 1 0 cwf21 domain PLDc_2 PF13091.6 EGG24484.1 - 1.7e-23 82.9 1.1 2.1e-17 63.3 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGG24484.1 - 8.3e-06 25.8 1.0 0.0059 16.7 0.3 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif SUI1 PF01253.22 EGG24485.1 - 6.3e-23 81.1 0.0 1.6e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 BNIP2 PF12496.8 EGG24485.1 - 0.034 14.6 0.5 0.056 13.9 0.5 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 ARPC4 PF05856.12 EGG24486.1 - 3e-78 261.2 9.5 3.4e-78 261.0 9.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Ank_4 PF13637.6 EGG24487.1 - 3.1e-17 62.7 5.1 1.2e-08 35.3 0.4 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG24487.1 - 2.1e-16 60.3 14.0 5.7e-07 30.0 0.6 4.1 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EGG24487.1 - 4e-10 39.7 12.0 0.01 16.2 0.7 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EGG24487.1 - 5.3e-09 35.6 4.5 0.078 13.6 0.2 6.0 5 0 0 5 5 5 3 Ankyrin repeat VPS9 PF02204.18 EGG24487.1 - 1.2e-07 31.9 0.1 3.2e-07 30.5 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 EGG24487.1 - 7.1e-06 26.2 0.9 5.4e-05 23.4 0.2 4.4 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Roughex PF06020.11 EGG24487.1 - 0.0063 15.7 4.5 0.014 14.5 4.5 1.5 1 0 0 1 1 1 1 Drosophila roughex protein DnaJ PF00226.31 EGG24488.1 - 3e-20 72.1 2.6 1.3e-19 70.0 0.2 3.0 2 0 0 2 2 2 1 DnaJ domain zinc_ribbon_4 PF13717.6 EGG24488.1 - 0.00029 20.7 3.1 0.0016 18.3 0.3 2.7 2 0 0 2 2 2 1 zinc-ribbon domain Lar_restr_allev PF14354.6 EGG24488.1 - 0.1 13.0 3.3 0.19 12.1 0.3 2.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar Prok-RING_4 PF14447.6 EGG24488.1 - 1.2 9.1 3.9 0.99 9.3 1.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Arf PF00025.21 EGG24489.1 - 3e-24 85.4 0.1 3.7e-24 85.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGG24489.1 - 6.8e-06 25.8 0.2 0.037 13.6 0.0 2.1 2 0 0 2 2 2 2 Ras family SRPRB PF09439.10 EGG24489.1 - 2.6e-05 23.8 1.5 4.2e-05 23.1 0.4 1.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGG24489.1 - 3.2e-05 24.0 0.2 0.00036 20.6 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGG24489.1 - 9.3e-05 22.6 0.2 0.00053 20.2 0.2 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGG24489.1 - 0.031 13.4 6.3 1.3 8.1 3.3 2.6 2 1 0 2 2 2 0 G-protein alpha subunit ATPase_2 PF01637.18 EGG24489.1 - 0.041 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SRP9-21 PF05486.12 EGG24490.1 - 0.024 15.0 0.9 0.036 14.4 0.9 1.3 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) BPL_N PF09825.9 EGG24490.1 - 0.047 12.8 0.5 0.051 12.7 0.5 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Spt20 PF12090.8 EGG24490.1 - 0.3 10.6 9.5 0.33 10.5 9.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF1751 PF08551.10 EGG24491.1 - 3e-22 79.0 4.2 3e-22 79.0 4.2 1.8 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EGG24491.1 - 1.4e-10 41.4 11.3 1.4e-10 41.4 11.3 1.7 2 0 0 2 2 2 1 Rhomboid family DUF2631 PF10939.8 EGG24491.1 - 0.1 12.5 7.4 0.87 9.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2631) PRA1 PF03208.19 EGG24491.1 - 1.8 8.2 8.0 0.53 9.9 0.1 2.8 3 0 0 3 3 3 0 PRA1 family protein Lon_C PF05362.13 EGG24492.1 - 1.1e-62 211.2 0.0 4.8e-52 176.5 0.0 2.3 2 0 0 2 2 2 2 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EGG24492.1 - 2e-24 86.5 0.0 9.6e-24 84.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EGG24492.1 - 2.2e-06 27.9 0.3 1.1e-05 25.6 0.0 2.3 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) LON_substr_bdg PF02190.16 EGG24492.1 - 3.8e-06 26.9 1.2 1e-05 25.5 0.1 2.3 1 1 1 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 EGG24492.1 - 8.7e-06 25.8 0.0 2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGG24492.1 - 7.7e-05 23.0 1.2 0.059 13.6 0.2 3.6 2 1 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 EGG24492.1 - 0.0001 21.4 0.0 0.00024 20.1 0.0 1.6 1 0 0 1 1 1 1 PrkA AAA domain MCM PF00493.23 EGG24492.1 - 0.00019 20.6 0.0 0.00044 19.4 0.0 1.6 1 0 0 1 1 1 1 MCM P-loop domain ChlI PF13541.6 EGG24492.1 - 0.00065 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase RuvB_N PF05496.12 EGG24492.1 - 0.0021 17.8 0.0 0.0088 15.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGG24492.1 - 0.0032 17.9 1.4 0.011 16.2 0.0 2.5 3 1 0 3 3 2 1 AAA ATPase domain AAA_11 PF13086.6 EGG24492.1 - 0.0098 15.7 9.0 0.81 9.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.11 EGG24492.1 - 0.0099 15.7 0.0 0.03 14.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGG24492.1 - 0.014 14.9 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 EGG24492.1 - 0.021 14.1 0.0 0.045 13.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain RsgA_GTPase PF03193.16 EGG24492.1 - 0.028 14.3 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 EGG24492.1 - 0.042 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 EGG24492.1 - 0.042 14.2 0.2 0.18 12.1 0.0 2.1 3 0 0 3 3 1 0 AAA domain AAA_30 PF13604.6 EGG24492.1 - 0.046 13.4 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain ClpB_D2-small PF10431.9 EGG24492.1 - 0.048 13.7 0.3 0.13 12.3 0.3 1.7 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_18 PF13238.6 EGG24492.1 - 0.079 13.5 0.0 0.079 13.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 EGG24492.1 - 0.1 11.9 0.0 0.31 10.4 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGG24492.1 - 0.1 12.5 0.0 0.46 10.4 0.0 2.1 2 0 0 2 2 1 0 NACHT domain AAA_28 PF13521.6 EGG24492.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGG24492.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PaO PF08417.12 EGG24492.1 - 0.14 12.3 0.0 0.47 10.6 0.0 1.9 2 0 0 2 2 1 0 Pheophorbide a oxygenase NB-ARC PF00931.22 EGG24492.1 - 0.14 11.3 0.1 0.14 11.3 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 EGG24492.1 - 0.19 12.3 0.1 0.19 12.3 0.1 2.7 3 0 0 3 3 2 0 ABC transporter DUF1041 PF06292.17 EGG24492.1 - 2.1 8.8 5.7 4.1 7.9 0.5 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) Tim54 PF11711.8 EGG24492.1 - 5 5.8 8.4 3.4 6.4 3.0 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Topoisom_I_N PF02919.15 EGG24492.1 - 5.1 6.5 7.6 0.51 9.8 0.6 2.2 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment UBX PF00789.20 EGG24493.1 - 6e-15 55.2 0.0 1.5e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 EGG24493.1 - 2.2e-12 47.0 0.0 1.3e-11 44.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.6 EGG24493.1 - 1.4e-10 40.8 0.4 4.8e-10 39.1 0.4 2.0 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_2 PF13098.6 EGG24493.1 - 0.00063 20.2 0.0 0.0019 18.7 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain SAPS PF04499.15 EGG24493.1 - 0.0024 16.7 4.8 0.0036 16.1 4.8 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Spore_coat_CotO PF14153.6 EGG24493.1 - 0.038 13.9 15.0 0.096 12.6 15.0 1.6 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.17 EGG24493.1 - 0.043 12.6 6.4 0.078 11.7 6.4 1.4 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 EGG24493.1 - 0.77 8.5 11.0 1.6 7.4 11.0 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 EGG24493.1 - 0.81 8.6 4.9 1.5 7.7 4.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 EGG24493.1 - 1.2 8.3 5.2 1.7 7.8 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Afi1 PF07792.12 EGG24493.1 - 1.9 9.0 14.4 0.43 11.1 10.1 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nop14 PF04147.12 EGG24493.1 - 2.1 6.5 20.6 3.2 5.8 20.6 1.2 1 0 0 1 1 1 0 Nop14-like family DDRGK PF09756.9 EGG24493.1 - 2.5 7.7 21.4 4.7 6.8 21.4 1.4 1 0 0 1 1 1 0 DDRGK domain DUF4746 PF15928.5 EGG24493.1 - 5.6 6.3 16.9 11 5.4 16.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 EGG24493.1 - 7.2 5.8 22.9 11 5.3 21.9 1.7 2 0 0 2 2 2 0 NOA36 protein V_ATPase_I PF01496.19 EGG24493.1 - 7.9 4.3 10.4 11 3.8 10.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Roughex PF06020.11 EGG24493.1 - 8.1 5.4 15.6 13 4.7 15.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Pkinase_Tyr PF07714.17 EGG24494.1 - 5.2e-68 229.1 0.1 1.5e-66 224.3 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGG24494.1 - 2.9e-54 184.2 0.0 2.9e-54 184.2 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain LRR_8 PF13855.6 EGG24494.1 - 1.7e-22 78.9 45.6 1.2e-10 41.0 8.1 3.6 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EGG24494.1 - 5.1e-22 77.6 42.2 1.5e-09 38.0 5.5 5.9 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) APH PF01636.23 EGG24494.1 - 0.00067 19.6 0.1 0.00067 19.6 0.1 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family LRR_6 PF13516.6 EGG24494.1 - 0.026 14.6 0.4 0.026 14.6 0.4 5.9 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 EGG24494.1 - 0.24 12.1 28.4 2.9 8.8 0.1 8.2 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_3 PF07725.12 EGG24494.1 - 2.7 8.0 5.8 1.5 8.8 0.6 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat zf-CCCH_4 PF18044.1 EGG24495.1 - 1.2e-15 56.8 34.7 1.1e-05 25.1 3.0 4.5 4 0 0 4 4 4 4 CCCH-type zinc finger Torus PF16131.5 EGG24495.1 - 1.7e-15 57.7 34.0 7.6e-05 23.4 1.0 5.2 3 2 2 5 5 5 4 Torus domain zf_CCCH_4 PF18345.1 EGG24495.1 - 2.4e-15 56.0 45.9 1.7e-05 24.7 5.6 4.7 4 1 0 4 4 4 4 Zinc finger domain zf-CCCH PF00642.24 EGG24495.1 - 2.9e-15 55.7 33.7 1.5e-05 24.7 2.3 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EGG24495.1 - 1.5e-07 31.7 35.2 0.0088 16.5 5.3 4.6 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-RING_2 PF13639.6 EGG24495.1 - 4.7e-07 30.0 4.8 4.7e-07 30.0 4.8 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 EGG24495.1 - 2.1e-06 27.5 3.6 2.1e-06 27.5 3.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG24495.1 - 1.2e-05 25.2 1.3 3.7e-05 23.7 0.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGG24495.1 - 0.0001 22.2 4.5 0.0001 22.2 4.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGG24495.1 - 0.0013 18.4 5.4 0.0032 17.2 5.4 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGG24495.1 - 0.0016 18.3 1.2 0.0016 18.3 1.2 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_3 PF15663.5 EGG24495.1 - 0.029 14.6 19.2 0.56 10.4 0.2 4.6 3 1 1 4 4 4 0 Zinc-finger containing family zf-C3HC4_4 PF15227.6 EGG24495.1 - 0.11 12.6 4.7 0.75 10.0 4.8 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Sar8_2 PF03058.14 EGG24495.1 - 1.1 9.8 6.8 1.9 9.1 0.1 3.8 3 0 0 3 3 3 0 Sar8.2 family zf-rbx1 PF12678.7 EGG24495.1 - 3.4 8.0 13.0 0.58 10.5 7.1 2.9 2 1 0 2 2 1 0 RING-H2 zinc finger domain Myb_DNA-binding PF00249.31 EGG24496.1 - 1.6e-30 105.0 18.4 2.4e-16 59.6 1.5 4.1 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG24496.1 - 2.2e-25 88.7 11.0 4.9e-16 58.7 0.5 4.2 3 1 1 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGG24496.1 - 5.3e-05 23.5 9.0 0.02 15.2 0.0 3.8 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGG24496.1 - 0.00034 20.7 0.9 1.7 8.9 0.0 3.5 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 EGG24496.1 - 0.0054 17.0 8.2 3.4 8.1 1.4 4.0 3 1 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SLIDE PF09111.10 EGG24496.1 - 0.0058 16.6 6.2 0.2 11.7 0.0 3.3 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EGG24496.1 - 0.052 13.4 0.9 1.8 8.5 0.2 2.9 2 0 0 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_5 PF13873.6 EGG24496.1 - 2.3 8.3 8.0 17 5.6 0.3 4.1 3 2 0 4 4 4 0 Myb/SANT-like DNA-binding domain Abhydrolase_6 PF12697.7 EGG24497.1 - 1.4e-21 78.1 0.0 2e-21 77.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG24497.1 - 9.2e-10 38.2 0.0 1.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGG24497.1 - 9.3e-10 38.6 0.0 8.2e-09 35.5 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EGG24497.1 - 2.9e-05 24.0 0.1 6.2e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Lipase (class 3) LIDHydrolase PF10230.9 EGG24497.1 - 0.00015 21.5 0.1 0.00023 20.8 0.1 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 EGG24497.1 - 0.001 18.9 1.5 0.0037 17.0 0.9 2.0 1 1 1 2 2 2 1 PGAP1-like protein Chlorophyllase2 PF12740.7 EGG24497.1 - 0.0015 17.5 0.1 0.0021 17.0 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 EGG24497.1 - 0.0028 17.5 0.0 0.024 14.5 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 EGG24497.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 EGG24497.1 - 0.029 14.1 0.1 0.053 13.3 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 EGG24497.1 - 0.038 13.5 0.2 0.059 12.9 0.2 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 EGG24497.1 - 0.05 13.4 2.7 0.54 10.1 0.2 2.5 3 0 0 3 3 3 0 Serine hydrolase Rxt3 PF08642.10 EGG24497.1 - 0.12 13.1 1.6 0.36 11.6 0.1 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Thioesterase PF00975.20 EGG24497.1 - 0.16 12.1 0.0 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain Pkinase PF00069.25 EGG24498.1 - 2.6e-62 210.6 2.2 2.6e-62 210.6 2.2 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG24498.1 - 9.2e-41 139.8 1.2 9.2e-41 139.8 1.2 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGG24498.1 - 0.047 13.6 1.9 0.091 12.7 0.0 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family Caudo_TAP PF02413.17 EGG24498.1 - 0.44 10.7 7.0 1.2 9.3 7.0 1.7 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK GATA PF00320.27 EGG24499.1 - 4.7e-16 58.1 5.9 1.3e-15 56.7 5.9 1.8 1 0 0 1 1 1 1 GATA zinc finger PhoPQ_related PF10142.9 EGG24500.1 - 1.4e-134 448.4 0.9 1.6e-134 448.2 0.9 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_S9 PF00326.21 EGG24500.1 - 0.011 15.2 0.0 0.025 14.0 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family GPI-anchored PF10342.9 EGG24500.1 - 0.018 15.8 2.7 0.2 12.4 0.4 2.7 2 1 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family LMBR1 PF04791.16 EGG24501.1 - 1.8e-113 380.2 18.3 2.1e-113 379.9 18.3 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Activator_LAG-3 PF11498.8 EGG24501.1 - 0.28 10.1 0.3 0.43 9.5 0.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ANAPC4_WD40 PF12894.7 EGG24502.1 - 6.2e-07 29.6 0.0 4.9 7.5 0.0 5.6 5 1 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Synaptobrevin PF00957.21 EGG24502.1 - 5.3e-06 26.1 3.0 1.2e-05 25.0 3.0 1.7 1 0 0 1 1 1 1 Synaptobrevin WD40 PF00400.32 EGG24502.1 - 0.0048 17.7 2.0 9.6 7.3 0.0 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat Ctr PF04145.15 EGG24502.1 - 0.43 11.2 1.9 1.8 9.2 0.0 3.0 3 0 0 3 3 3 0 Ctr copper transporter family BLOC1_2 PF10046.9 EGG24502.1 - 1.8 8.9 5.2 2.5 8.5 1.6 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAP PF07174.11 EGG24502.1 - 7.3 6.0 18.4 0.33 10.4 0.1 2.3 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) HEAT PF02985.22 EGG24503.1 - 1.5e-12 46.6 15.5 0.078 13.3 0.0 10.5 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.6 EGG24503.1 - 4e-10 40.0 0.9 0.88 10.1 0.0 8.0 7 1 1 8 8 8 3 HEAT-like repeat Cnd1 PF12717.7 EGG24503.1 - 4.5e-10 39.8 17.9 4.4e-06 26.8 0.1 7.0 3 3 3 7 7 7 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGG24503.1 - 5e-09 36.1 18.2 0.042 13.4 0.0 7.2 8 1 0 8 8 8 4 CLASP N terminal HEAT_2 PF13646.6 EGG24503.1 - 2e-08 34.5 0.0 1.6 9.2 0.0 6.8 6 1 1 7 7 7 2 HEAT repeats Vac14_Fab1_bd PF12755.7 EGG24503.1 - 8.2e-08 32.7 10.3 2.9 8.5 0.2 7.5 5 3 3 8 8 8 3 Vacuolar 14 Fab1-binding region UME PF08064.13 EGG24503.1 - 9.5e-07 28.7 0.7 0.021 14.7 0.0 5.5 4 0 0 4 4 4 1 UME (NUC010) domain IBN_N PF03810.19 EGG24503.1 - 2.7e-05 24.0 3.3 0.00075 19.4 1.8 3.7 2 1 1 3 3 3 1 Importin-beta N-terminal domain ParcG PF10274.9 EGG24503.1 - 0.00012 22.3 4.3 0.14 12.2 0.0 5.0 4 2 1 5 5 5 1 Parkin co-regulated protein Tti2 PF10521.9 EGG24503.1 - 0.00018 21.2 7.7 0.029 13.9 0.0 5.6 4 3 1 5 5 5 1 Tti2 family MMS19_C PF12460.8 EGG24503.1 - 0.00025 20.3 13.3 0.33 10.0 0.0 5.7 3 2 3 6 6 6 2 RNAPII transcription regulator C-terminal Importin_rep_4 PF18808.1 EGG24503.1 - 0.0032 17.7 3.7 0.11 12.7 0.0 3.6 2 0 0 2 2 2 1 Importin repeat DUF3385 PF11865.8 EGG24503.1 - 0.026 14.4 0.1 0.026 14.4 0.1 8.1 5 4 5 11 11 11 0 Domain of unknown function (DUF3385) RIX1 PF08167.12 EGG24503.1 - 0.041 13.6 5.5 0.89 9.3 0.1 4.6 5 1 0 5 5 5 0 rRNA processing/ribosome biogenesis Cohesin_HEAT PF12765.7 EGG24503.1 - 0.1 13.0 0.2 37 4.7 0.0 3.5 3 0 0 3 3 2 0 HEAT repeat associated with sister chromatid cohesion NUC130_3NT PF08158.12 EGG24503.1 - 0.17 12.2 3.3 2.3 8.6 0.2 4.1 4 0 0 4 4 4 0 NUC130/3NT domain V-ATPase_H_N PF03224.14 EGG24503.1 - 0.6 9.3 11.0 4.3 6.5 0.1 4.3 3 3 2 5 5 5 0 V-ATPase subunit H CENP-B_dimeris PF09026.10 EGG24503.1 - 5.7 7.4 9.2 0.51 10.7 2.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NTP_transf_7 PF07984.12 EGG24505.1 - 1.1e-30 107.0 9.1 5.4e-14 52.2 0.0 3.2 3 0 0 3 3 3 3 Nucleotidyltransferase Peptidase_C39_2 PF13529.6 EGG24505.1 - 3.5e-15 56.8 0.3 3.5e-15 56.8 0.3 3.7 2 1 1 3 3 3 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 EGG24505.1 - 7.2e-11 42.3 0.0 1.5e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 EGG24505.1 - 6.7e-06 25.9 0.1 0.00022 21.0 0.0 2.9 3 0 0 3 3 3 1 Peptidase C39 family Guanylate_cyc_2 PF09778.9 EGG24505.1 - 0.0041 16.5 0.0 0.77 9.1 0.0 2.4 2 0 0 2 2 2 2 Guanylylate cyclase BtrH_N PF14399.6 EGG24505.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal Macoilin PF09726.9 EGG24506.1 - 0.015 13.9 12.3 0.055 12.0 1.3 2.2 2 0 0 2 2 2 0 Macoilin family DUF2992 PF11208.8 EGG24507.1 - 0.52 10.6 0.0 0.52 10.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Rho_N PF07498.12 EGG24507.1 - 1.5 8.9 5.0 4.8 7.2 0.2 3.5 4 0 0 4 4 4 0 Rho termination factor, N-terminal domain zf-MYND PF01753.18 EGG24508.1 - 1.2e-07 31.7 13.8 1.2e-07 31.7 13.8 2.0 2 0 0 2 2 2 1 MYND finger zinc-ribbons_6 PF07191.12 EGG24508.1 - 0.041 13.9 6.5 0.11 12.5 6.5 1.6 1 0 0 1 1 1 0 zinc-ribbons Sulfate_transp PF00916.20 EGG24509.1 - 1.6e-106 356.3 23.6 2.1e-106 355.9 23.6 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGG24509.1 - 1.1e-20 73.4 0.0 3e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EGG24509.1 - 0.025 14.9 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 STAS domain Ras PF00071.22 EGG24510.1 - 1.8e-45 154.4 0.1 2.1e-45 154.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG24510.1 - 7.5e-14 52.0 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG24510.1 - 3.9e-07 29.7 0.1 4.9e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGG24510.1 - 4.2e-05 23.5 0.1 0.001 19.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EGG24510.1 - 0.0064 16.5 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Ser_hydrolase PF06821.13 EGG24510.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase MMR_HSR1 PF01926.23 EGG24510.1 - 0.034 14.2 0.0 0.052 13.6 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG24510.1 - 0.1 12.1 0.3 0.23 11.0 0.3 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Hpr_kinase_C PF07475.12 EGG24510.1 - 0.16 11.5 1.5 6.9 6.2 1.5 2.2 1 1 0 1 1 1 0 HPr Serine kinase C-terminal domain ELYS PF13934.6 EGG24511.1 - 2.1e-21 76.9 2.0 3.5e-21 76.2 0.9 1.9 2 0 0 2 2 2 1 Nuclear pore complex assembly ELYS-bb PF16687.5 EGG24511.1 - 9.4e-10 37.7 0.1 8e-06 24.7 0.0 2.4 2 0 0 2 2 2 2 beta-propeller of ELYS nucleoporin Amino_oxidase PF01593.24 EGG24512.1 - 1.3e-62 212.6 0.0 1.5e-62 212.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGG24512.1 - 2e-14 53.6 0.1 4.2e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGG24512.1 - 1.3e-06 27.8 0.2 1.9e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGG24512.1 - 7e-06 25.6 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGG24512.1 - 7.1e-06 25.0 0.1 3.3e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EGG24512.1 - 7.4e-06 25.4 0.0 5.5e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGG24512.1 - 9.2e-06 25.5 0.0 2.1e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGG24512.1 - 0.00018 22.0 0.1 0.00057 20.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGG24512.1 - 0.0017 17.7 0.7 0.013 14.8 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGG24512.1 - 0.0048 16.0 0.2 0.068 12.3 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EGG24512.1 - 0.0071 15.6 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EGG24512.1 - 0.015 14.3 0.0 0.069 12.2 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EGG24512.1 - 0.088 12.0 0.2 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EGG24512.1 - 0.15 12.0 0.0 8.4 6.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EGG24512.1 - 0.21 10.8 0.1 0.39 10.0 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LIM PF00412.22 EGG24513.1 - 1.1e-15 57.6 21.9 1.6e-08 34.6 5.2 3.9 2 1 2 4 4 4 3 LIM domain Pribosyltran_N PF13793.6 EGG24513.1 - 0.019 14.9 0.0 0.065 13.2 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase Androgen_recep PF02166.16 EGG24513.1 - 3.5 6.4 17.3 0.24 10.2 0.6 2.3 2 0 0 2 2 2 0 Androgen receptor VWA PF00092.28 EGG24514.1 - 5.5e-07 30.0 0.1 9.2e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGG24514.1 - 0.00016 22.2 0.0 0.00016 22.2 0.0 2.1 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EGG24514.1 - 0.12 11.8 0.0 0.87 8.9 0.0 2.0 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein DDRGK PF09756.9 EGG24514.1 - 1.1 8.9 18.3 3.5 7.2 0.0 2.5 2 0 0 2 2 2 0 DDRGK domain Glyco_hydro_64 PF16483.5 EGG24515.1 - 0.0013 18.1 1.0 0.0021 17.4 1.0 1.3 1 0 0 1 1 1 1 Beta-1,3-glucanase SUIM_assoc PF16619.5 EGG24515.1 - 0.0074 16.3 0.2 0.0074 16.3 0.2 2.7 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 LPG_synthase_TM PF03706.13 EGG24516.1 - 6.1e-05 22.7 1.1 9.3e-05 22.1 0.1 1.6 2 0 0 2 2 2 1 Lysylphosphatidylglycerol synthase TM region Amastin PF07344.11 EGG24516.1 - 7.1e-05 22.7 5.6 0.00072 19.4 0.1 2.1 1 1 1 2 2 2 1 Amastin surface glycoprotein STE2 PF02116.15 EGG24516.1 - 0.0018 17.7 6.8 0.24 10.7 2.9 2.3 2 0 0 2 2 2 2 Fungal pheromone mating factor STE2 GPCR DUF2207 PF09972.9 EGG24516.1 - 0.0019 17.0 3.0 0.0019 17.0 3.0 2.3 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) BCD PF15461.6 EGG24516.1 - 0.013 15.0 2.3 0.025 14.1 2.0 1.7 1 1 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase DUF4231 PF14015.6 EGG24516.1 - 0.018 15.5 0.6 0.018 15.5 0.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Deltameth_res PF16020.5 EGG24516.1 - 0.025 14.4 0.0 0.025 14.4 0.0 2.8 3 1 0 3 3 3 0 Deltamethrin resistance Mem_trans PF03547.18 EGG24516.1 - 0.054 11.9 5.1 0.022 13.1 0.5 2.0 1 1 1 2 2 2 0 Membrane transport protein DUF2721 PF11026.8 EGG24516.1 - 0.073 13.0 9.0 0.11 12.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF2371 PF10177.9 EGG24516.1 - 0.18 12.0 0.8 0.36 11.0 0.8 1.6 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) CaKB PF03185.15 EGG24516.1 - 0.96 9.1 4.4 0.26 10.9 0.2 2.1 1 1 0 2 2 2 0 Calcium-activated potassium channel, beta subunit Cadherin_C_2 PF16492.5 EGG24516.1 - 1.2 9.9 6.5 2.8 8.8 0.0 2.9 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal DUF1218 PF06749.12 EGG24516.1 - 1.3 9.6 13.8 1.4 9.5 0.2 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1218) SUR7 PF06687.12 EGG24516.1 - 4 7.0 19.4 0.035 13.7 5.5 2.6 1 1 1 2 2 2 0 SUR7/PalI family MARVEL PF01284.23 EGG24517.1 - 8.7e-06 25.8 0.2 0.025 14.6 0.2 2.4 1 1 0 2 2 2 2 Membrane-associating domain 7TM_GPCR_Srw PF10324.9 EGG24517.1 - 0.00065 19.1 0.7 0.00065 19.1 0.7 1.6 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw Amastin PF07344.11 EGG24517.1 - 0.0014 18.5 0.8 0.0025 17.7 0.6 1.7 1 1 0 1 1 1 1 Amastin surface glycoprotein Gaa1 PF04114.14 EGG24517.1 - 0.0018 17.4 0.2 0.0023 17.1 0.2 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component CD20 PF04103.15 EGG24517.1 - 0.0026 17.8 0.1 0.0026 17.8 0.1 2.4 2 1 1 3 3 3 1 CD20-like family SUR7 PF06687.12 EGG24517.1 - 0.0057 16.3 3.6 0.0057 16.3 3.6 2.0 1 1 1 2 2 2 1 SUR7/PalI family BCD PF15461.6 EGG24517.1 - 0.015 14.8 0.1 0.015 14.8 0.1 1.6 2 0 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase Deltameth_res PF16020.5 EGG24517.1 - 0.029 14.2 0.0 0.029 14.2 0.0 2.7 3 0 0 3 3 3 0 Deltamethrin resistance UbiA PF01040.18 EGG24517.1 - 0.09 12.1 0.1 0.09 12.1 0.1 2.4 3 0 0 3 3 3 0 UbiA prenyltransferase family DUF4231 PF14015.6 EGG24517.1 - 0.11 12.9 0.4 0.11 12.9 0.4 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) CaKB PF03185.15 EGG24517.1 - 0.24 11.1 3.6 0.31 10.7 0.2 2.3 1 1 1 2 2 2 0 Calcium-activated potassium channel, beta subunit DUF4131 PF13567.6 EGG24517.1 - 0.86 9.2 4.1 3.1 7.4 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF1218 PF06749.12 EGG24517.1 - 2 9.0 10.7 1.2 9.7 0.2 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1218) DUF2207 PF09972.9 EGG24517.1 - 2.8 6.6 11.2 0.11 11.2 4.4 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF3040 PF11239.8 EGG24517.1 - 3.7 7.9 6.0 47 4.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) HMG_box PF00505.19 EGG24518.1 - 2.6e-17 63.0 1.2 2.6e-17 63.0 1.2 2.3 3 0 0 3 3 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGG24518.1 - 4.5e-12 46.4 0.3 4.5e-12 46.4 0.3 2.2 3 0 0 3 3 2 1 HMG-box domain DUF2721 PF11026.8 EGG24518.1 - 0.0038 17.1 4.3 0.02 14.8 0.7 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) MARVEL PF01284.23 EGG24518.1 - 0.017 15.1 9.2 0.084 12.9 9.2 1.9 1 1 0 1 1 1 0 Membrane-associating domain TMEM40 PF15817.5 EGG24518.1 - 0.14 12.0 4.3 0.22 11.3 0.1 2.4 2 0 0 2 2 2 0 Transmembrane protein 40 family YABBY PF04690.13 EGG24518.1 - 0.16 12.5 5.5 0.11 13.1 3.6 1.8 2 0 0 2 2 2 0 YABBY protein Ureide_permease PF07168.11 EGG24518.1 - 0.17 10.6 4.6 0.043 12.6 0.3 2.1 2 1 0 2 2 2 0 Ureide permease CDC45 PF02724.14 EGG24518.1 - 0.33 9.2 7.8 0.5 8.6 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 EGG24518.1 - 2.5 8.1 6.5 6.2 6.8 6.4 1.9 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1218 PF06749.12 EGG24518.1 - 3.4 8.3 7.8 15 6.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Glycoprotein_G PF00802.19 EGG24518.1 - 9.2 5.5 15.9 0.78 9.1 10.4 2.0 2 0 0 2 2 2 0 Pneumovirus attachment glycoprotein G Glyco_hydro_25 PF01183.20 EGG24519.1 - 0.00061 20.0 3.5 0.0017 18.6 3.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 25 DUF2292 PF10055.9 EGG24519.1 - 0.098 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) DUF1906 PF08924.11 EGG24519.1 - 0.13 12.4 4.8 0.22 11.6 4.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1906) Glyco_hydro_25 PF01183.20 EGG24520.1 - 0.0015 18.7 0.2 0.0017 18.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 GHL6 PF14871.6 EGG24520.1 - 0.067 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 4HBT_2 PF13279.6 EGG24521.1 - 3.8e-08 33.9 0.0 5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EGG24521.1 - 0.026 14.9 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase superfamily Rap_GAP PF02145.15 EGG24522.1 - 8.8e-61 204.7 2.4 8.8e-61 204.7 2.4 2.4 2 0 0 2 2 2 2 Rap/ran-GAP CoaE PF01121.20 EGG24523.1 - 7.5e-47 159.3 0.3 9.2e-47 159.0 0.3 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EGG24523.1 - 2.6e-05 24.7 1.3 0.00033 21.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 EGG24523.1 - 0.0096 16.2 0.3 0.057 13.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain Trs65 PF12735.7 EGG24523.1 - 0.018 14.4 0.1 0.022 14.2 0.1 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 dNK PF01712.19 EGG24523.1 - 0.042 13.7 0.5 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF2267 PF10025.9 EGG24523.1 - 0.056 13.7 0.2 0.086 13.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) SKI PF01202.22 EGG24523.1 - 0.16 12.1 1.8 3.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase Retrotran_gag_2 PF14223.6 EGG24524.1 - 0.024 14.3 0.2 0.048 13.3 0.2 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Ephrin_rec_like PF07699.13 EGG24525.1 - 0.00015 21.5 3.0 0.00015 21.5 3.0 5.8 3 1 3 6 6 6 3 Putative ephrin-receptor like Spectrin_like PF18373.1 EGG24525.1 - 1.5 8.9 6.3 3.1 7.9 0.9 2.9 2 0 0 2 2 2 0 Spectrin like domain DUF4363 PF14276.6 EGG24525.1 - 1.9 8.7 10.1 0.07 13.3 3.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) zf-RING_2 PF13639.6 EGG24526.1 - 2.8e-09 37.1 9.1 2.8e-09 37.1 9.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGG24526.1 - 6.9e-08 32.2 7.5 1.6e-07 31.1 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG24526.1 - 9.3e-07 28.6 8.3 2e-06 27.5 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG24526.1 - 3.1e-06 26.9 5.4 6.6e-06 25.9 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG24526.1 - 1.3e-05 25.1 5.7 4.2e-05 23.5 5.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGG24526.1 - 3.8e-05 23.4 8.1 9.5e-05 22.1 8.1 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EGG24526.1 - 0.0033 17.5 5.1 0.017 15.3 5.1 2.4 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGG24526.1 - 0.0036 17.5 11.3 0.023 15.0 11.3 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGG24526.1 - 0.0037 17.2 7.3 0.0037 17.2 7.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGG24526.1 - 0.0066 16.3 7.4 0.031 14.2 7.5 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 EGG24526.1 - 0.0078 16.2 1.4 0.021 14.8 1.4 1.7 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 EGG24526.1 - 0.036 13.9 6.2 0.043 13.7 4.7 1.9 1 1 1 2 2 2 0 zf-RING of BARD1-type protein FdhE PF04216.12 EGG24526.1 - 0.19 11.5 4.4 0.26 11.1 4.4 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DZR PF12773.7 EGG24526.1 - 0.33 11.0 6.1 0.85 9.7 5.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 EGG24526.1 - 0.54 10.6 7.2 2.6 8.4 2.8 3.0 2 0 0 2 2 2 0 zinc-ribbon DUF1272 PF06906.11 EGG24526.1 - 0.66 10.1 5.7 1.4 9.1 4.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_10 PF16685.5 EGG24526.1 - 1.1 9.4 12.6 0.045 13.9 5.5 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 EGG24526.1 - 1.4 8.7 7.3 6.2 6.7 7.3 2.2 1 1 0 1 1 1 0 RING-like zinc finger zinc-ribbons_6 PF07191.12 EGG24526.1 - 4.8 7.2 9.1 0.91 9.5 5.2 1.9 2 0 0 2 2 1 0 zinc-ribbons Pkinase PF00069.25 EGG24528.1 - 6.9e-53 179.7 0.0 1.6e-52 178.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG24528.1 - 9.3e-32 110.3 0.0 1.8e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SUIM_assoc PF16619.5 EGG24528.1 - 1.3e-05 25.1 1.3 0.00024 21.1 0.0 3.1 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 NusA_N PF08529.11 EGG24528.1 - 0.0042 17.5 3.7 0.0099 16.2 3.7 1.6 1 0 0 1 1 1 1 NusA N-terminal domain Kdo PF06293.14 EGG24528.1 - 0.015 14.6 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.14 EGG24528.1 - 0.039 12.2 9.7 0.056 11.7 6.4 2.1 2 0 0 2 2 2 0 CDC45-like protein Kinase-like PF14531.6 EGG24528.1 - 0.049 13.0 3.0 0.24 10.7 0.0 2.8 2 2 1 3 3 3 0 Kinase-like MIT PF04212.18 EGG24529.1 - 9.9e-10 38.3 1.3 1.9e-09 37.4 1.3 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 EGG24529.1 - 0.12 12.6 0.0 0.53 10.5 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_2 PF12796.7 EGG24530.1 - 2.3e-25 89.0 3.2 1.8e-08 34.9 0.6 4.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24530.1 - 7.9e-20 71.0 2.7 0.016 15.7 0.0 8.0 6 2 1 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24530.1 - 2.9e-18 65.7 6.4 0.12 12.7 0.0 9.0 3 3 8 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24530.1 - 1.2e-11 43.7 7.5 0.61 10.8 0.0 9.2 10 1 1 11 11 11 3 Ankyrin repeat Ank PF00023.30 EGG24530.1 - 2.6e-06 27.6 2.4 90 3.8 0.0 7.7 6 2 2 8 8 8 0 Ankyrin repeat DUF3447 PF11929.8 EGG24530.1 - 1.9e-05 24.5 2.1 0.15 12.0 0.0 4.4 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) DUF5049 PF16468.5 EGG24530.1 - 0.093 12.6 0.0 6.8 6.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5049) HMG_CoA_synt_C PF08540.10 EGG24531.1 - 8.6e-96 320.8 5.0 1.1e-95 320.5 5.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EGG24531.1 - 3.9e-90 300.4 0.2 7.2e-90 299.5 0.2 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Myb_Cef PF11831.8 EGG24531.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component WD40 PF00400.32 EGG24532.1 - 1.7e-61 202.7 27.2 9.5e-11 42.1 0.6 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG24532.1 - 1.3e-18 67.1 2.6 2e-05 24.8 0.0 5.4 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGG24532.1 - 5.7e-13 48.4 5.2 0.078 11.6 0.0 5.8 1 1 4 6 6 6 4 Nucleoporin Nup120/160 LisH PF08513.11 EGG24532.1 - 9e-07 28.6 0.3 1.7e-06 27.8 0.3 1.5 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.11 EGG24532.1 - 2.2e-06 26.7 0.2 0.0016 17.3 0.0 3.5 3 1 1 4 4 4 2 Nup133 N terminal like Ge1_WD40 PF16529.5 EGG24532.1 - 0.011 14.7 8.2 4.4 6.2 0.4 4.1 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGG24532.1 - 0.083 12.2 0.3 1.5 8.1 0.1 2.8 2 2 2 4 4 4 0 WD40-like domain DASH_Spc19 PF08287.11 EGG24532.1 - 0.09 12.7 0.3 0.15 12.0 0.3 1.2 1 0 0 1 1 1 0 Spc19 PALB2_WD40 PF16756.5 EGG24532.1 - 0.58 9.0 6.3 20 4.0 0.1 4.4 2 2 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain AAA PF00004.29 EGG24533.1 - 2.8e-91 302.8 1.6 3.4e-47 160.2 0.0 3.8 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) Nucleolin_bd PF16725.5 EGG24533.1 - 4.8e-20 71.0 0.9 1e-19 70.0 0.9 1.6 1 0 0 1 1 1 1 Nucleolin binding domain AAA_lid_3 PF17862.1 EGG24533.1 - 1.9e-18 66.0 0.3 2.4e-09 36.8 0.0 3.1 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 EGG24533.1 - 2.1e-15 56.8 0.0 5.5e-07 29.5 0.0 3.7 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGG24533.1 - 7e-14 52.3 1.7 9.4e-07 29.1 0.0 3.3 4 0 0 4 4 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGG24533.1 - 1.2e-12 48.5 2.7 0.0014 19.0 0.0 5.0 3 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 EGG24533.1 - 7.2e-10 39.0 0.9 0.0028 17.7 0.0 4.1 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGG24533.1 - 4.9e-09 36.5 0.0 0.0018 18.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGG24533.1 - 5.6e-09 36.4 1.5 0.0058 16.9 0.1 4.7 3 2 1 4 4 3 2 AAA domain RNA_helicase PF00910.22 EGG24533.1 - 8.1e-09 35.8 0.0 0.014 15.8 0.0 3.8 3 0 0 3 3 3 2 RNA helicase AAA_14 PF13173.6 EGG24533.1 - 6.1e-08 32.8 0.0 0.019 15.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.13 EGG24533.1 - 6.4e-08 32.2 0.0 0.0013 18.0 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Vps4_C PF09336.10 EGG24533.1 - 9.3e-08 32.0 0.2 0.00072 19.5 0.0 2.7 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 EGG24533.1 - 2.2e-07 30.4 1.7 0.018 14.5 0.0 2.8 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EGG24533.1 - 4e-07 29.8 0.2 1.5 8.4 0.0 4.4 3 1 0 4 4 4 3 AAA domain NACHT PF05729.12 EGG24533.1 - 9.8e-07 28.8 0.1 0.22 11.4 0.0 4.2 3 1 1 4 4 4 2 NACHT domain Zeta_toxin PF06414.12 EGG24533.1 - 6.5e-06 25.6 0.1 0.02 14.2 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.17 EGG24533.1 - 1.3e-05 25.0 1.0 0.05 13.3 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 EGG24533.1 - 1.8e-05 25.0 1.4 0.27 11.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain TsaE PF02367.17 EGG24533.1 - 5.1e-05 23.3 0.0 0.22 11.5 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EGG24533.1 - 6.9e-05 22.8 0.0 0.64 9.9 0.0 3.2 2 0 0 2 2 2 2 Rad17 P-loop domain ATPase PF06745.13 EGG24533.1 - 0.0001 21.8 0.5 1.2 8.4 0.0 3.4 2 1 1 3 3 3 2 KaiC AAA_7 PF12775.7 EGG24533.1 - 0.00013 21.5 0.0 0.64 9.5 0.0 3.0 2 1 0 2 2 2 2 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EGG24533.1 - 0.0002 21.2 0.6 0.82 9.4 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 EGG24533.1 - 0.00027 21.3 1.5 1.5 9.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.11 EGG24533.1 - 0.0003 20.6 0.0 0.52 10.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGG24533.1 - 0.00032 20.7 0.0 1.2 9.0 0.0 4.1 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 EGG24533.1 - 0.00053 19.7 0.1 0.38 10.4 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 EGG24533.1 - 0.00055 19.2 0.0 1.7 7.8 0.0 3.3 3 0 0 3 3 3 2 NB-ARC domain PhoH PF02562.16 EGG24533.1 - 0.0012 18.4 0.2 0.43 10.0 0.1 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.6 EGG24533.1 - 0.0028 17.4 0.0 1.6 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EGG24533.1 - 0.0032 17.4 0.3 2.9 7.8 0.0 3.6 4 1 1 5 5 4 1 NTPase ABC_tran PF00005.27 EGG24533.1 - 0.0055 17.2 0.0 0.036 14.6 0.0 4.4 3 1 1 4 4 2 2 ABC transporter Cytidylate_kin2 PF13189.6 EGG24533.1 - 0.012 15.8 0.2 6.1 6.9 0.0 2.8 3 0 0 3 3 2 0 Cytidylate kinase-like family AAA_19 PF13245.6 EGG24533.1 - 0.026 14.9 0.3 14 6.0 0.2 3.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGG24533.1 - 0.073 13.6 15.4 0.37 11.3 0.0 4.8 5 1 0 5 5 4 0 AAA domain EF-hand_6 PF13405.6 EGG24533.1 - 0.11 12.4 0.2 0.89 9.7 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain MDD_C PF18376.1 EGG24534.1 - 5.6e-69 231.6 0.0 9.5e-69 230.9 0.0 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EGG24534.1 - 2.4e-06 27.7 2.1 5.8e-06 26.5 2.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain FERM_N PF09379.10 EGG24537.1 - 0.0004 20.3 0.0 0.13 12.3 0.0 2.7 2 0 0 2 2 2 2 FERM N-terminal domain TUG-UBL1 PF11470.8 EGG24537.1 - 0.00047 20.3 0.0 0.0021 18.2 0.0 2.1 1 0 0 1 1 1 1 TUG ubiquitin-like domain Choline_kinase PF01633.20 EGG24538.1 - 1.1e-60 204.8 0.0 2.7e-60 203.6 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EGG24538.1 - 1.6e-11 44.6 0.0 3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGG24538.1 - 0.0091 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase LSM PF01423.22 EGG24539.1 - 8.7e-16 57.4 0.6 1.3e-15 56.8 0.6 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGG24539.1 - 4.7e-05 23.4 0.0 6.5e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Ataxin 2 SM domain SUIM_assoc PF16619.5 EGG24539.1 - 0.002 18.2 3.6 0.0025 17.9 3.6 1.2 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 GRP PF07172.11 EGG24539.1 - 0.04 14.6 27.6 0.064 13.9 27.6 1.3 1 0 0 1 1 1 0 Glycine rich protein family Feld-I_B PF09252.10 EGG24539.1 - 0.12 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Allergen Fel d I-B chain Med3 PF11593.8 EGG24539.1 - 0.15 11.3 1.8 0.19 10.9 1.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Kelch_4 PF13418.6 EGG24540.1 - 3e-44 148.8 10.9 9.2e-12 44.8 0.0 7.5 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 EGG24540.1 - 1.8e-33 114.1 14.9 1.9e-11 44.0 0.0 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGG24540.1 - 3.8e-33 112.9 11.1 1.1e-06 28.4 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EGG24540.1 - 2.7e-30 103.6 13.3 7.8e-08 32.3 0.3 6.2 3 2 3 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EGG24540.1 - 2.8e-26 90.9 2.1 8e-07 28.5 0.1 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EGG24540.1 - 3.8e-24 83.7 9.5 6.7e-06 25.9 0.0 6.1 6 0 0 6 6 6 4 Kelch motif zf-C3HC4_3 PF13920.6 EGG24540.1 - 1.7e-13 50.2 9.1 2.8e-13 49.5 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG24540.1 - 1.1e-06 28.4 10.1 2.2e-06 27.4 10.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 K-box PF01486.17 EGG24540.1 - 6.6e-06 26.2 10.9 6.6e-06 26.2 10.9 3.7 4 1 0 4 4 2 1 K-box region zf-RING_5 PF14634.6 EGG24540.1 - 0.0015 18.4 9.6 0.0027 17.6 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGG24540.1 - 0.0046 17.3 11.5 0.0087 16.4 11.5 1.5 1 0 0 1 1 1 1 Ring finger domain RAG2 PF03089.14 EGG24540.1 - 0.0047 16.0 0.1 0.29 10.1 0.1 3.2 2 1 1 3 3 3 1 Recombination activating protein 2 DUF3854 PF12965.7 EGG24540.1 - 0.41 10.6 8.0 0.097 12.7 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3854) DUF2039 PF10217.9 EGG24540.1 - 0.74 10.2 11.4 0.16 12.3 5.5 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) FNIP PF05725.12 EGG24541.1 - 0.00038 20.6 26.9 0.1 12.8 0.0 8.0 6 3 1 7 7 7 4 FNIP Repeat FNIP PF05725.12 EGG24542.1 - 0.0031 17.6 33.0 0.84 9.9 0.0 8.8 5 3 4 9 9 9 6 FNIP Repeat TIG PF01833.24 EGG24543.1 - 3e-09 36.8 19.0 4.8e-05 23.3 0.6 5.3 4 1 0 4 4 4 3 IPT/TIG domain RCR PF12273.8 EGG24543.1 - 0.044 14.4 1.8 0.06 14.0 0.2 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red EGF_2 PF07974.13 EGG24543.1 - 0.14 12.5 7.4 0.43 11.0 7.4 1.8 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.27 EGG24543.1 - 0.24 11.7 8.9 0.88 9.9 8.9 2.0 1 0 0 1 1 1 0 EGF-like domain Sigma_reg_N PF13800.6 EGG24543.1 - 1.2 9.4 15.2 0.33 11.3 5.6 3.1 3 0 0 3 3 3 0 Sigma factor regulator N-terminal hEGF PF12661.7 EGG24543.1 - 1.8 9.3 6.6 8.7 7.1 6.6 2.3 1 0 0 1 1 1 0 Human growth factor-like EGF TMEM154 PF15102.6 EGG24543.1 - 4.3 7.2 10.8 0.41 10.5 0.9 2.6 2 0 0 2 2 2 0 TMEM154 protein family FNIP PF05725.12 EGG24544.1 - 1.4e-97 319.6 49.2 3.7e-16 59.0 1.3 11.1 8 2 4 12 12 12 11 FNIP Repeat PI3Ka PF00613.20 EGG24544.1 - 1.3e-60 204.0 1.9 2.5e-60 203.0 1.9 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGG24544.1 - 2.4e-54 184.8 0.1 5.2e-53 180.4 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EGG24544.1 - 3e-24 85.5 0.0 9.5e-24 83.9 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Pkinase PF00069.25 EGG24544.1 - 8.1e-16 58.2 0.3 3.7e-15 56.0 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain PI3K_rbd PF00794.18 EGG24544.1 - 4.2e-10 39.7 4.0 6.3e-08 32.7 0.0 3.9 4 0 0 4 4 4 2 PI3-kinase family, ras-binding domain Pkinase_Tyr PF07714.17 EGG24544.1 - 5.5e-07 29.1 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Dickkopf_N PF04706.12 EGG24545.1 - 0.0017 18.8 9.0 0.0017 18.8 9.0 6.7 3 1 4 7 7 7 4 Dickkopf N-terminal cysteine-rich region WYL_2 PF10902.8 EGG24546.1 - 0.57 10.6 3.6 1.7 9.1 1.9 2.4 1 1 1 2 2 2 0 WYL_2, Sm-like SH3 beta-barrel fold C1_1 PF00130.22 EGG24547.1 - 1.5e-10 40.8 34.5 3.2e-06 26.9 6.9 3.2 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4690 PF15756.5 EGG24548.1 - 1.4e-06 28.8 0.2 4.3e-06 27.2 0.2 1.8 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Rax2 PF12768.7 EGG24548.1 - 0.002 17.7 0.1 0.0043 16.5 0.1 1.6 1 0 0 1 1 1 1 Cortical protein marker for cell polarity UBA2_C PF16195.5 EGG24548.1 - 0.78 10.5 10.4 1.6 9.5 10.4 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus DNase_II PF03265.15 EGG24549.1 - 3.9e-19 69.1 7.7 3.5e-18 66.0 4.9 2.9 2 1 1 3 3 3 1 Deoxyribonuclease II FAM176 PF14851.6 EGG24549.1 - 2 8.1 9.0 34 4.1 1.9 3.4 3 0 0 3 3 3 0 FAM176 family RR_TM4-6 PF06459.12 EGG24549.1 - 4 7.2 6.3 1 9.2 0.3 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SLT PF01464.20 EGG24550.1 - 1e-10 41.3 0.0 1.3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.20 EGG24550.1 - 2.2e-06 27.9 8.8 6.2e-06 26.5 8.0 2.0 1 1 1 2 2 2 1 C-type lysozyme/alpha-lactalbumin family Transglycosylas PF06737.14 EGG24550.1 - 0.0058 17.2 0.0 0.0093 16.6 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase-like domain 4HB_MCP_1 PF12729.7 EGG24550.1 - 0.13 11.8 0.4 0.18 11.3 0.4 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction zf-TRAF PF02176.18 EGG24551.1 - 2.5e-12 47.3 25.9 6.1e-05 23.6 1.1 4.1 2 1 1 3 3 3 3 TRAF-type zinc finger Sina PF03145.16 EGG24551.1 - 1.1e-06 28.7 21.2 0.00045 20.2 1.6 3.4 1 1 2 3 3 3 3 Seven in absentia protein family zf-TRAF_2 PF15965.5 EGG24551.1 - 3.3e-06 27.5 5.6 3.3e-06 27.5 5.6 3.2 3 1 1 4 4 4 2 TRAF-like zinc-finger SVWC PF15430.6 EGG24551.1 - 0.0014 18.8 4.0 0.0014 18.8 4.0 3.5 3 0 0 3 3 3 1 Single domain von Willebrand factor type C Rad50_zn_hook PF04423.14 EGG24551.1 - 0.0018 18.0 0.4 1.7 8.5 0.1 2.9 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C3HC4_2 PF13923.6 EGG24551.1 - 0.16 11.9 6.6 1.2 9.1 6.6 2.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PA14 PF07691.12 EGG24552.1 - 2e-07 30.9 0.0 4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGG24552.1 - 6.3e-06 26.0 2.5 6.3e-06 26.0 2.5 14.2 13 2 1 14 14 14 4 Dictyostelium (slime mold) repeat SapB_1 PF05184.15 EGG24554.1 - 8.1e-23 80.1 14.2 1.7e-11 43.9 1.8 2.9 3 0 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.17 EGG24554.1 - 8e-21 73.8 5.2 2.1e-09 37.3 2.8 3.1 2 0 0 2 2 2 2 Saposin-like type B, region 2 Sec23_trunk PF04811.15 EGG24555.1 - 7.3e-64 215.6 0.1 1.1e-63 215.0 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGG24555.1 - 2.1e-19 70.0 0.5 2.1e-19 70.0 0.5 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EGG24555.1 - 4.9e-18 64.8 0.2 1.5e-17 63.3 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EGG24555.1 - 2.1e-14 53.3 2.1 2.9e-14 52.8 0.8 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGG24555.1 - 0.32 10.9 3.6 0.64 10.0 0.0 2.7 2 0 0 2 2 2 0 Gelsolin repeat Dickkopf_N PF04706.12 EGG24556.1 - 0.011 16.2 17.6 0.027 15.0 1.6 6.4 5 2 0 5 5 5 0 Dickkopf N-terminal cysteine-rich region FANCI_S2 PF14676.6 EGG24557.1 - 0.001 19.4 1.1 0.001 19.4 1.1 2.7 2 1 0 2 2 2 1 FANCI solenoid 2 Urb2 PF10441.9 EGG24557.1 - 0.27 11.1 8.3 2.3 8.1 3.1 3.2 3 1 0 3 3 3 0 Urb2/Npa2 family Ank_2 PF12796.7 EGG24558.1 - 1.9e-06 28.4 5.8 0.003 18.1 0.1 5.2 4 3 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG24558.1 - 5.1e-06 26.4 0.9 7.5 7.5 0.0 6.3 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 EGG24558.1 - 7.5e-06 26.4 0.3 0.019 15.5 0.0 4.4 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24558.1 - 0.00037 20.7 0.3 2.7 8.4 0.0 5.8 6 1 1 7 7 7 1 Ankyrin repeats (many copies) RIH_assoc PF08454.11 EGG24558.1 - 7.5 6.5 8.1 0.54 10.1 0.3 3.0 2 1 0 2 2 2 0 RyR and IP3R Homology associated Fz PF01392.22 EGG24560.1 - 1.3e-05 25.7 4.5 3.3e-05 24.5 4.5 1.7 1 0 0 1 1 1 1 Fz domain Sigma_reg_N PF13800.6 EGG24560.1 - 0.21 11.9 2.1 2.8 8.3 0.1 2.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF4682 PF15733.5 EGG24560.1 - 4.2 8.0 5.2 0.74 10.4 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4682) Ank_2 PF12796.7 EGG24562.1 - 6.7e-10 39.4 0.1 4.2e-06 27.3 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG24562.1 - 9.2e-05 22.6 0.0 1.1 10.0 0.0 4.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EGG24562.1 - 0.0008 19.9 0.3 9.6 6.9 0.0 5.1 7 0 0 7 7 7 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 EGG24562.1 - 0.00083 19.3 1.0 0.0055 16.6 0.1 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 EGG24562.1 - 0.17 12.3 0.1 19 5.7 0.0 3.5 2 1 1 3 3 3 0 Ankyrin repeats (many copies) XLF PF09302.11 EGG24563.1 - 1.7e-13 51.1 12.1 1.7e-13 51.1 12.1 2.7 2 1 1 3 3 3 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Androgen_recep PF02166.16 EGG24563.1 - 1.9 7.2 11.1 3.1 6.5 11.1 1.2 1 0 0 1 1 1 0 Androgen receptor EGF_2 PF07974.13 EGG24564.1 - 0.0034 17.7 7.3 0.0056 17.0 7.3 1.4 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 EGG24564.1 - 0.041 14.2 9.0 0.091 13.1 9.0 1.5 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EGG24564.1 - 3.2 7.9 8.1 4.9 7.3 8.1 1.3 1 0 0 1 1 1 0 Tenascin EGF domain C2 PF00168.30 EGG24566.1 - 0.052 13.8 0.0 0.084 13.2 0.0 1.4 1 0 0 1 1 1 0 C2 domain EGF_2 PF07974.13 EGG24567.1 - 0.004 17.5 7.0 0.0078 16.6 7.0 1.5 1 0 0 1 1 1 1 EGF-like domain TIG PF01833.24 EGG24567.1 - 0.0089 16.1 2.1 0.0089 16.1 2.1 2.6 1 1 1 2 2 2 1 IPT/TIG domain hEGF PF12661.7 EGG24567.1 - 2.1 9.1 6.7 5.6 7.8 6.7 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF OSTbeta PF15048.6 EGG24568.1 - 0.00028 21.0 1.2 0.0004 20.5 1.2 1.2 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein PRIMA1 PF16101.5 EGG24568.1 - 0.0041 17.1 0.2 0.0056 16.7 0.2 1.2 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 TMEM154 PF15102.6 EGG24568.1 - 0.0077 16.1 1.2 0.011 15.7 1.0 1.4 1 1 0 1 1 1 1 TMEM154 protein family SieB PF14163.6 EGG24568.1 - 0.016 14.7 0.5 0.026 14.0 0.5 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B Neurensin PF14927.6 EGG24568.1 - 0.063 13.0 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Neurensin Ly49 PF08391.10 EGG24568.1 - 0.1 13.0 6.3 0.16 12.4 6.3 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region SCIMP PF15050.6 EGG24568.1 - 0.28 11.7 2.8 0.43 11.0 2.8 1.3 1 0 0 1 1 1 0 SCIMP protein DUF3139 PF11337.8 EGG24568.1 - 0.28 11.8 2.0 0.5 11.1 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Thioredoxin PF00085.20 EGG24570.1 - 8.9e-52 173.4 5.1 4.5e-29 100.5 0.3 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EGG24570.1 - 5.3e-09 36.5 6.1 0.0011 19.4 1.2 3.0 3 1 0 3 3 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EGG24570.1 - 8.6e-09 35.2 2.3 0.0012 18.3 0.0 2.3 1 1 0 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EGG24570.1 - 7.5e-08 32.3 0.9 0.00025 20.9 0.1 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 EGG24570.1 - 6.9e-07 29.5 2.5 0.04 14.2 0.5 4.0 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_6 PF13848.6 EGG24570.1 - 4.4e-06 26.7 0.3 0.032 14.1 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGG24570.1 - 3.5e-05 23.9 0.3 0.24 11.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 EGG24570.1 - 7e-05 22.6 2.3 0.044 13.5 0.3 2.3 2 0 0 2 2 2 2 Redoxin TraF PF13728.6 EGG24570.1 - 0.00019 21.3 0.5 0.1 12.4 0.1 3.0 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EGG24570.1 - 0.00057 19.7 0.0 0.081 12.7 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 EGG24570.1 - 0.0018 18.3 1.3 0.46 10.6 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin domain HyaE PF07449.11 EGG24570.1 - 0.12 12.3 0.0 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 EGG24570.1 - 0.15 12.3 3.8 5.9 7.2 0.4 2.6 2 0 0 2 2 2 0 Glutaredoxin Vps53_N PF04100.12 EGG24571.1 - 1.5e-107 359.9 14.3 2.7e-107 359.0 14.3 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 EGG24571.1 - 7.5e-11 41.8 5.2 2.3e-10 40.3 5.2 1.8 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG7 PF10191.9 EGG24571.1 - 2.4e-05 22.8 8.9 4.1e-05 22.0 0.3 3.1 3 0 0 3 3 3 2 Golgi complex component 7 (COG7) COG5 PF10392.9 EGG24571.1 - 0.00045 20.4 2.0 0.0017 18.5 2.0 2.0 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF2451 PF10474.9 EGG24571.1 - 0.0013 18.6 1.9 0.0048 16.7 0.1 3.0 3 1 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) Cnl2_NKP2 PF09447.10 EGG24571.1 - 0.0077 16.4 1.6 0.035 14.3 0.1 3.0 4 0 0 4 4 4 1 Cnl2/NKP2 family protein XhlA PF10779.9 EGG24571.1 - 0.0099 16.1 2.9 0.0099 16.1 2.9 3.2 4 0 0 4 4 4 1 Haemolysin XhlA COG2 PF06148.11 EGG24571.1 - 0.069 13.2 5.3 0.77 9.8 4.5 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF234 PF03008.14 EGG24572.1 - 0.027 14.9 0.0 0.084 13.3 0.0 1.8 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function DUF835 PF05763.12 EGG24573.1 - 0.034 13.9 0.0 0.037 13.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF835) Ras PF00071.22 EGG24575.1 - 3.7e-52 176.2 2.7 1.3e-38 132.1 0.1 2.9 3 0 0 3 3 3 2 Ras family Roc PF08477.13 EGG24575.1 - 7e-22 77.9 0.1 1.4e-12 47.8 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGG24575.1 - 3.9e-06 26.5 0.2 1.3e-05 24.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 EGG24575.1 - 4e-06 26.4 2.3 0.00097 18.6 0.0 3.7 4 1 1 5 5 5 2 ADP-ribosylation factor family zf-Sec23_Sec24 PF04810.15 EGG24575.1 - 7.9e-05 22.6 1.9 0.00016 21.7 1.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_trunk PF04811.15 EGG24575.1 - 0.00053 19.6 0.0 0.028 14.0 0.0 2.8 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain RsgA_GTPase PF03193.16 EGG24575.1 - 0.00054 19.9 0.0 0.0016 18.4 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase VWA_2 PF13519.6 EGG24575.1 - 0.007 17.0 0.1 1.3 9.7 0.1 3.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Sec23_BS PF08033.12 EGG24575.1 - 0.028 15.2 1.2 0.062 14.0 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 beta-sandwich domain FeoB_N PF02421.18 EGG24575.1 - 0.031 13.8 0.0 0.25 10.9 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGG24575.1 - 0.037 14.1 0.0 4.1 7.5 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase TniB PF05621.11 EGG24575.1 - 0.044 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein DUF2076 PF09849.9 EGG24575.1 - 0.053 13.6 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) LRR_4 PF12799.7 EGG24576.1 - 0.00029 21.2 5.6 0.42 11.1 0.0 5.0 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG24576.1 - 0.0025 17.5 0.0 7 6.5 0.0 3.6 3 0 0 3 3 3 2 Leucine rich repeat EGF_2 PF07974.13 EGG24576.1 - 0.048 14.0 30.8 0.031 14.6 10.4 2.7 2 0 0 2 2 2 0 EGF-like domain YflT PF11181.8 EGG24578.1 - 0.14 12.7 0.5 0.57 10.7 0.1 2.3 2 1 0 2 2 2 0 Heat induced stress protein YflT ABC2_membrane_3 PF12698.7 EGG24579.1 - 0.24 10.5 5.3 0.28 10.2 5.3 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein LRR_4 PF12799.7 EGG24580.1 - 5.4e-11 42.5 37.8 6.5e-05 23.2 5.7 4.7 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGG24580.1 - 6.6e-09 35.5 17.8 3.2e-05 23.5 8.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EGG24580.1 - 6.8e-07 29.0 32.4 3.4e-05 23.5 6.6 4.6 3 2 1 5 5 5 3 Leucine rich repeat DUF848 PF05852.11 EGG24580.1 - 0.41 10.8 3.9 0.57 10.3 1.9 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4894 PF16235.5 EGG24580.1 - 0.57 10.6 7.4 1.1 9.6 7.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4894) Nop PF01798.18 EGG24581.1 - 6.9e-83 277.6 0.2 6.9e-83 277.6 0.2 2.1 2 0 0 2 2 1 1 snoRNA binding domain, fibrillarin Ank_2 PF12796.7 EGG24581.1 - 2e-15 57.1 3.8 1.8e-05 25.3 0.4 5.3 4 2 2 6 6 5 4 Ankyrin repeats (3 copies) NOP5NT PF08156.13 EGG24581.1 - 2.1e-13 50.5 0.8 1e-12 48.2 0.1 2.7 2 0 0 2 2 1 1 NOP5NT (NUC127) domain Ank_4 PF13637.6 EGG24581.1 - 1.4e-12 47.9 0.3 0.16 12.6 0.1 8.0 8 2 0 8 8 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24581.1 - 1.7e-08 34.6 0.4 2.3 8.6 0.0 7.5 5 1 3 8 8 8 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24581.1 - 1.6e-07 31.1 0.7 7.1 7.6 0.0 7.1 7 0 0 7 7 5 1 Ankyrin repeat DDHD PF02862.17 EGG24581.1 - 0.0058 16.8 1.2 0.0099 16.1 1.2 1.4 1 0 0 1 1 1 1 DDHD domain RR_TM4-6 PF06459.12 EGG24581.1 - 0.018 14.9 19.2 0.029 14.2 19.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 EGG24581.1 - 0.073 11.8 9.7 0.12 11.2 9.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 V_ATPase_I PF01496.19 EGG24581.1 - 0.16 9.9 10.6 0.26 9.2 8.8 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 EGG24581.1 - 0.17 10.8 8.2 0.31 10.0 8.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EGG24581.1 - 0.47 9.2 13.5 0.74 8.5 13.5 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGG24581.1 - 0.55 8.4 18.9 0.86 7.8 18.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Ank PF00023.30 EGG24581.1 - 0.58 10.7 1.9 4.8e+02 1.5 0.0 5.2 5 1 0 5 5 5 0 Ankyrin repeat Vfa1 PF08432.10 EGG24581.1 - 1 9.7 25.5 1.9 8.8 25.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF789 PF05623.12 EGG24581.1 - 1.9 8.1 10.4 3.3 7.3 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Connexin PF00029.19 EGG24581.1 - 2 8.1 11.6 4.4 7.0 11.6 1.5 1 0 0 1 1 1 0 Connexin SLC12 PF03522.15 EGG24581.1 - 2.3 7.1 16.1 4 6.4 16.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 EGG24581.1 - 2.9 6.6 16.3 5.2 5.7 16.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.16 EGG24581.1 - 3.2 7.7 7.2 6 6.9 7.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RP-C_C PF11800.8 EGG24581.1 - 7.2 6.7 12.3 4.8 7.2 9.7 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region VIR_N PF15912.5 EGG24581.1 - 8.3 5.9 17.4 17 4.9 17.4 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal Cpn60_TCP1 PF00118.24 EGG24582.1 - 3.1e-156 520.8 5.9 3.8e-156 520.5 5.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sdh_cyt PF01127.22 EGG24583.1 - 6.9e-19 68.1 2.8 6.2e-17 61.8 0.2 2.2 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit F-box PF00646.33 EGG24584.1 - 1.3e-06 28.1 1.6 1.3e-06 28.1 1.6 2.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EGG24584.1 - 3.4e-05 23.6 3.3 5e-05 23.1 1.7 2.1 2 0 0 2 2 2 1 F-box-like TrmB PF01978.19 EGG24584.1 - 0.11 12.4 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB FNIP PF05725.12 EGG24586.1 - 4.3e-07 30.0 10.2 0.047 13.9 0.0 7.3 7 2 1 8 8 8 3 FNIP Repeat Dapper PF15268.6 EGG24587.1 - 0.1 11.5 14.7 0.11 11.4 14.7 1.1 1 0 0 1 1 1 0 Dapper Nop PF01798.18 EGG24587.1 - 0.35 10.3 8.3 0.66 9.4 8.3 1.6 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Hid1 PF12722.7 EGG24587.1 - 1.9 6.5 17.8 2.3 6.3 17.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PRP1_N PF06424.12 EGG24587.1 - 7.2 7.0 17.0 12 6.3 17.0 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Peptidase_C97 PF05903.14 EGG24588.1 - 0.061 13.1 0.1 0.075 12.9 0.1 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain COX6B PF02297.17 EGG24588.1 - 0.21 11.8 5.4 1.3 9.4 1.1 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cadherin_pro PF08758.11 EGG24592.1 - 0.007 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Cadherin prodomain like SprB PF13573.6 EGG24597.1 - 0.0051 16.6 11.1 0.013 15.3 0.6 4.1 3 0 0 3 3 3 2 SprB repeat CBS PF00571.28 EGG24598.1 - 9.2e-27 93.3 4.3 5.4e-08 33.2 0.0 4.3 4 0 0 4 4 4 4 CBS domain RRM_1 PF00076.22 EGG24599.1 - 3.2e-49 164.6 4.4 1.1e-20 73.2 1.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGG24599.1 - 1.2e-09 37.8 0.1 4.2e-07 29.6 0.3 3.0 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGG24599.1 - 1.6e-06 28.1 0.1 0.019 15.0 0.1 3.3 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 EGG24599.1 - 5.6e-05 22.9 0.1 0.032 14.1 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif BRAP2 PF07576.12 EGG24599.1 - 6.8e-05 23.0 0.7 0.14 12.4 0.1 2.3 2 0 0 2 2 2 2 BRCA1-associated protein 2 RRM_3 PF08777.11 EGG24599.1 - 0.00035 20.6 1.5 0.013 15.5 0.3 3.1 2 2 1 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 EGG24599.1 - 0.0019 18.2 0.1 0.23 11.5 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EGG24599.1 - 0.0033 17.7 2.8 7.9 6.7 0.1 4.5 2 2 2 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter Phage_TTP_12 PF16461.5 EGG24599.1 - 0.0092 15.7 0.1 1.9 8.2 0.0 2.5 2 0 0 2 2 2 1 Lambda phage tail tube protein, TTP ICAP-1_inte_bdg PF10480.9 EGG24599.1 - 0.31 11.0 1.3 0.54 10.2 1.3 1.3 1 0 0 1 1 1 0 Beta-1 integrin binding protein DUF5423 PF17461.2 EGG24599.1 - 2.3 7.0 6.0 4.7 6.0 6.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5423) TIG PF01833.24 EGG24600.1 - 6.4e-15 55.0 48.2 2.9e-07 30.5 5.6 7.9 7 1 0 7 7 7 5 IPT/TIG domain EGF_2 PF07974.13 EGG24600.1 - 0.00019 21.7 29.0 0.056 13.8 12.1 2.9 2 0 0 2 2 2 2 EGF-like domain DUF5300 PF17224.3 EGG24600.1 - 0.02 15.2 2.6 4.9 7.5 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5300) Lectin_C PF00059.21 EGG24600.1 - 0.53 11.0 0.0 0.53 11.0 0.0 3.9 5 0 0 5 5 5 0 Lectin C-type domain hEGF PF12661.7 EGG24600.1 - 0.55 11.0 17.9 1.3 9.7 5.3 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.27 EGG24600.1 - 1.5 9.2 28.7 1.9 8.9 8.7 3.1 3 0 0 3 3 3 0 EGF-like domain EGF_Tenascin PF18720.1 EGG24600.1 - 1.8 8.7 26.4 0.26 11.4 12.1 2.8 2 0 0 2 2 2 0 Tenascin EGF domain Sigma_reg_N PF13800.6 EGG24600.1 - 8.1 6.8 8.0 3.7 7.9 1.7 3.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal TIG PF01833.24 EGG24601.1 - 1.2e-12 47.8 22.7 9.1e-07 28.9 2.1 4.7 4 0 0 4 4 4 3 IPT/TIG domain EGF_2 PF07974.13 EGG24601.1 - 0.25 11.7 22.0 0.21 12.0 8.4 2.9 2 0 0 2 2 2 0 EGF-like domain Paired_CXXCH_1 PF09699.10 EGG24602.1 - 0.87 9.4 6.7 1.9 8.3 0.5 3.1 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) Caldesmon PF02029.15 EGG24602.1 - 8.6 5.0 92.0 0.016 14.0 43.9 3.4 3 0 0 3 3 3 0 Caldesmon PHD_4 PF16866.5 EGG24603.1 - 1.7 8.8 6.1 34 4.6 0.1 4.3 4 0 0 4 4 4 0 PHD-finger OmpH PF03938.14 EGG24603.1 - 5.2 7.4 27.2 18 5.6 27.2 1.9 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Adeno_PV PF03910.13 EGG24604.1 - 0.22 10.2 0.5 0.42 9.3 0.5 1.4 1 0 0 1 1 1 0 Adenovirus minor core protein PV SR-25 PF10500.9 EGG24605.1 - 0.0036 17.0 19.5 0.0036 17.0 19.5 6.2 5 1 1 6 6 6 2 Nuclear RNA-splicing-associated protein TIG PF01833.24 EGG24607.1 - 8.9e-06 25.7 1.6 8.9e-06 25.7 1.6 2.4 2 0 0 2 2 2 1 IPT/TIG domain EGF_2 PF07974.13 EGG24607.1 - 0.41 11.1 11.5 0.066 13.6 6.9 2.0 2 0 0 2 2 2 0 EGF-like domain CholecysA-Rec_N PF09193.10 EGG24608.1 - 0.17 11.9 3.8 2.3 8.3 0.0 3.8 3 1 1 4 4 4 0 Cholecystokinin A receptor, N-terminal EGF_2 PF07974.13 EGG24608.1 - 3.7 8.0 39.8 0.16 12.4 10.8 3.9 3 0 0 3 3 3 0 EGF-like domain EGF_2 PF07974.13 EGG24609.1 - 2.8e-05 24.4 31.6 0.015 15.6 11.7 2.8 2 0 0 2 2 2 2 EGF-like domain fn3 PF00041.21 EGG24609.1 - 0.001 19.3 5.0 2.5 8.5 0.0 5.1 6 0 0 6 6 6 2 Fibronectin type III domain KH_dom-like PF14714.6 EGG24609.1 - 0.037 14.3 0.0 13 6.2 0.0 3.1 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Nop14 PF04147.12 EGG24610.1 - 2 6.5 25.5 3.2 5.9 25.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF5093 PF17011.5 EGG24610.1 - 9.4 6.5 9.1 0.14 12.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) SET PF00856.28 EGG24611.1 - 4.6e-05 23.9 0.7 0.00012 22.5 0.0 2.0 2 0 0 2 2 2 1 SET domain zf-TRAF PF02176.18 EGG24614.1 - 0.84 10.4 15.5 0.98 10.2 0.4 2.9 2 1 0 2 2 2 0 TRAF-type zinc finger LIM PF00412.22 EGG24615.1 - 0.028 14.6 5.7 0.028 14.6 5.7 2.6 1 1 1 2 2 2 0 LIM domain DZR PF12773.7 EGG24615.1 - 8.2 6.5 12.7 0.48 10.5 2.9 2.6 2 1 1 3 3 3 0 Double zinc ribbon EGF_2 PF07974.13 EGG24618.1 - 0.00059 20.2 16.4 0.0013 19.0 16.4 1.6 1 0 0 1 1 1 1 EGF-like domain VirK PF06903.12 EGG24618.1 - 0.078 13.1 0.6 0.17 12.0 0.6 1.5 1 0 0 1 1 1 0 VirK protein Spore_GerAC PF05504.11 EGG24618.1 - 0.16 12.2 0.3 1.5 9.0 0.0 2.2 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal EGF PF00008.27 EGG24618.1 - 0.95 9.8 10.5 1.8 8.9 10.5 1.5 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.24 EGG24618.1 - 1.4 9.1 11.8 1.8 8.7 0.3 3.0 3 0 0 3 3 3 0 IPT/TIG domain Plasmod_Pvs28 PF06247.11 EGG24618.1 - 2 8.8 9.7 6.9 7.1 9.7 1.9 1 0 0 1 1 1 0 Pvs28 EGF domain Beach PF02138.18 EGG24619.1 - 4.6e-121 403.4 0.2 4.6e-121 403.4 0.2 3.0 3 0 0 3 3 3 1 Beige/BEACH domain DUF4704 PF15787.5 EGG24619.1 - 1e-58 198.8 1.6 1e-58 198.8 1.6 4.8 4 2 0 4 4 4 2 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 EGG24619.1 - 2.6e-26 91.6 0.2 2.6e-26 91.6 0.2 2.9 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 EGG24619.1 - 3.9e-15 55.8 1.0 3.9e-15 55.8 1.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) WD40 PF00400.32 EGG24619.1 - 9e-13 48.5 15.7 1.6e-05 25.6 0.2 6.0 5 1 1 6 6 6 3 WD domain, G-beta repeat DUF1088 PF06469.11 EGG24619.1 - 0.00055 19.7 0.2 0.0017 18.1 0.2 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) ANAPC4_WD40 PF12894.7 EGG24619.1 - 0.00061 20.0 0.7 2.7 8.3 0.2 4.4 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Arm PF00514.23 EGG24619.1 - 0.022 14.8 0.7 0.38 10.9 0.0 3.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ank_2 PF12796.7 EGG24620.1 - 3.3e-09 37.2 4.9 8.9e-05 23.0 0.0 5.0 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24620.1 - 7.5e-07 29.6 1.7 0.075 13.6 0.0 5.6 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24620.1 - 0.0031 17.9 1.3 20 6.2 0.0 6.3 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 EGG24620.1 - 0.019 15.2 0.0 30 5.1 0.0 4.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) ASL_C2 PF14698.6 EGG24620.1 - 0.085 13.6 0.0 4.4 8.1 0.0 2.8 1 1 1 2 2 2 0 Argininosuccinate lyase C-terminal Ank_2 PF12796.7 EGG24621.1 - 7.1e-06 26.5 0.0 0.00091 19.8 0.0 3.6 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EGG24621.1 - 2.1e-05 24.4 7.3 0.15 12.0 0.0 5.0 3 2 1 4 4 4 2 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EGG24621.1 - 0.00011 22.3 0.0 10 7.0 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EGG24621.1 - 0.0042 17.6 0.0 0.04 14.5 0.0 2.9 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG24622.1 - 4.2e-06 27.3 0.0 0.00074 20.0 0.0 3.7 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG24622.1 - 0.0026 18.1 0.0 13 6.8 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EGG24622.1 - 0.035 14.7 0.0 3.5 8.3 0.0 3.8 4 1 0 5 5 5 0 Ankyrin repeats (many copies) FixP_N PF14715.6 EGG24622.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Ank_2 PF12796.7 EGG24623.1 - 0.0013 19.2 0.0 0.35 11.5 0.0 4.1 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24623.1 - 0.033 14.8 0.1 48 4.7 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG24626.1 - 0.00012 22.6 0.2 0.45 11.1 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Secretin_N_2 PF07655.13 EGG24626.1 - 0.06 13.9 16.1 0.14 12.7 16.1 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain MID_MedPIWI PF18296.1 EGG24626.1 - 0.061 13.1 3.9 0.14 11.9 3.9 1.5 1 0 0 1 1 1 0 MID domain of medPIWI Corazonin PF17308.2 EGG24626.1 - 0.25 11.7 17.1 0.61 10.5 17.1 1.6 1 0 0 1 1 1 0 Pro-corazonin Folliculin PF11704.8 EGG24626.1 - 0.25 11.2 1.9 0.49 10.3 1.9 1.5 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport AIF_C PF14721.6 EGG24626.1 - 0.6 10.5 6.0 1.1 9.6 6.0 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PRC2_HTH_1 PF18118.1 EGG24626.1 - 0.77 10.6 4.3 2.2 9.2 4.3 1.7 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Menin PF05053.13 EGG24626.1 - 1.1 7.5 7.8 1.9 6.8 7.8 1.2 1 0 0 1 1 1 0 Menin RNA_pol_Rbc25 PF08292.12 EGG24626.1 - 5.8 7.2 5.6 56 4.0 3.0 2.4 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Apc15p PF05841.11 EGG24626.1 - 6.9 7.5 17.2 17 6.2 17.2 1.7 1 0 0 1 1 1 0 Apc15p protein Ank_2 PF12796.7 EGG24627.1 - 1.3e-05 25.7 0.3 0.59 10.7 0.0 4.2 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EGG24627.1 - 0.00094 19.1 6.1 0.017 15.1 0.1 4.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 EGG24627.1 - 0.068 13.8 0.6 9.1 7.2 0.0 4.9 7 0 0 7 7 7 0 Ankyrin repeat Ank_4 PF13637.6 EGG24627.1 - 0.093 13.3 0.0 18 6.0 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Nramp PF01566.18 EGG24628.1 - 2.4e-126 421.5 22.6 2.4e-126 421.5 22.6 2.9 2 2 1 3 3 3 1 Natural resistance-associated macrophage protein TPT PF03151.16 EGG24628.1 - 4.2e-51 174.0 21.2 4.2e-51 174.0 21.2 2.6 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.20 EGG24628.1 - 1.1e-06 28.8 28.6 1.1e-05 25.7 15.7 5.6 4 2 1 5 5 5 2 EamA-like transporter family UAA PF08449.11 EGG24628.1 - 6.4e-06 25.6 19.4 6.4e-06 25.6 19.4 2.2 2 0 0 2 2 2 1 UAA transporter family Granulin PF00396.18 EGG24629.1 - 2.7e-12 46.8 21.7 2.7e-12 46.8 21.7 2.1 1 1 1 2 2 2 2 Granulin DUP PF00674.18 EGG24629.1 - 0.046 13.9 0.7 0.067 13.3 0.7 1.2 1 0 0 1 1 1 0 DUP family UCR_UQCRX_QCR9 PF05365.12 EGG24630.1 - 2e-17 62.9 1.5 2.4e-17 62.6 1.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like UQ_con PF00179.26 EGG24631.1 - 1.5e-45 154.3 0.0 1.7e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGG24631.1 - 0.015 15.5 0.1 0.019 15.3 0.1 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 EGG24631.1 - 0.032 13.9 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 EGG24631.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UEV PF05743.13 EGG24631.1 - 0.13 12.2 0.2 0.2 11.5 0.2 1.3 1 1 0 1 1 1 0 UEV domain Tmpp129 PF10272.9 EGG24632.1 - 0.00061 19.2 22.3 0.035 13.4 0.3 2.3 2 0 0 2 2 2 2 Putative transmembrane protein precursor Drc1-Sld2 PF11719.8 EGG24632.1 - 0.62 9.6 50.3 0.011 15.4 36.2 2.1 2 0 0 2 2 2 0 DNA replication and checkpoint protein DUF2052 PF09747.9 EGG24632.1 - 6 6.9 41.7 0.17 12.0 26.0 3.2 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) FA_desaturase PF00487.24 EGG24632.1 - 7 6.4 7.0 13 5.5 7.0 1.4 1 0 0 1 1 1 0 Fatty acid desaturase PUB PF09409.10 EGG24633.1 - 0.049 13.6 0.0 2.8 7.9 0.0 2.6 2 0 0 2 2 2 0 PUB domain PH_RBD PF12068.8 EGG24633.1 - 0.59 9.6 5.2 1.6 8.2 0.1 2.3 2 0 0 2 2 2 0 Rab-binding domain (RBD) CUE PF02845.16 EGG24634.1 - 1.1e-07 31.4 0.0 2.8e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 EGG24634.1 - 0.025 14.7 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Med27 PF11571.8 EGG24634.1 - 0.1 13.0 2.6 1.3 9.4 0.0 3.5 3 0 0 3 3 3 0 Mediator complex subunit 27 DUF3446 PF11928.8 EGG24634.1 - 4.3 7.7 18.2 8.5 6.8 8.0 3.3 3 0 0 3 3 3 0 Early growth response N-terminal domain Acetyltransf_3 PF13302.7 EGG24636.1 - 7.2e-12 46.2 0.0 9.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Hydantoinase_B PF02538.14 EGG24637.1 - 9.2e-217 720.5 0.8 1.7e-216 719.6 0.8 1.4 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EGG24637.1 - 6.8e-99 330.8 0.0 1.6e-98 329.6 0.0 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGG24637.1 - 1e-58 198.0 0.4 2.2e-56 190.4 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF4083 PF13314.6 EGG24639.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) ATP11 PF06644.11 EGG24641.1 - 7.7e-34 117.7 0.1 7.7e-34 117.7 0.1 2.1 2 0 0 2 2 2 1 ATP11 protein GSIII_N PF12437.8 EGG24642.1 - 5.1e-70 234.3 0.0 9.6e-70 233.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 EGG24642.1 - 1.3e-37 128.2 0.8 2.9e-37 127.1 0.1 2.0 2 0 0 2 2 2 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 EGG24642.1 - 3.5e-15 55.9 0.0 5.9e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain MFS_1 PF07690.16 EGG24643.1 - 2.9e-38 131.7 28.0 5.4e-26 91.4 10.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGG24643.1 - 1.3e-12 47.4 9.2 1.3e-12 47.4 9.2 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter Tim17 PF02466.19 EGG24643.1 - 0.11 12.9 2.7 0.11 12.8 0.3 2.3 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Claudin_3 PF06653.11 EGG24643.1 - 1.8 8.5 11.8 0.048 13.6 1.1 3.2 3 0 0 3 3 3 0 Tight junction protein, Claudin-like RskA PF10099.9 EGG24644.1 - 0.00066 20.0 2.4 0.0027 18.0 2.4 2.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Cnn_1N PF07989.11 EGG24644.1 - 0.011 15.9 4.3 0.011 15.9 4.3 12.8 7 2 5 13 13 13 0 Centrosomin N-terminal motif 1 RRN3 PF05327.11 EGG24645.1 - 0.003 16.2 4.0 0.0041 15.7 4.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 RXT2_N PF08595.11 EGG24645.1 - 0.68 10.0 5.7 1.4 9.0 5.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 EGG24645.1 - 0.85 8.7 18.1 1.2 8.2 18.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 EGG24645.1 - 1.6 6.8 15.4 2 6.4 15.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 EGG24645.1 - 2.9 7.4 11.3 6.5 6.3 11.3 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CobT PF06213.12 EGG24645.1 - 3.6 6.9 9.7 85 2.4 9.7 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Pex2_Pex12 PF04757.14 EGG24647.1 - 7.5e-37 127.1 5.1 1.3e-36 126.4 5.0 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EGG24647.1 - 0.00015 21.6 3.9 0.00023 20.9 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG24647.1 - 0.0023 18.2 6.0 0.0041 17.4 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGG24647.1 - 0.0025 17.6 6.2 0.0049 16.7 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG24647.1 - 0.014 15.3 6.2 0.03 14.2 6.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG24647.1 - 0.067 13.2 9.8 0.12 12.4 9.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGG24647.1 - 0.9 9.8 8.9 1.6 9.0 8.9 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FNIP PF05725.12 EGG24648.1 - 2e-07 31.0 0.0 4.6e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 FNIP Repeat Phage_min_tail PF05939.13 EGG24648.1 - 0.059 13.8 0.1 0.15 12.5 0.1 1.6 1 1 0 1 1 1 0 Phage minor tail protein Isy1 PF06246.12 EGG24649.1 - 8.9e-81 271.2 14.3 1e-80 271.0 14.3 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Xylo_C PF12529.8 EGG24649.1 - 0.0072 16.0 0.4 0.012 15.2 0.4 1.4 1 0 0 1 1 1 1 Xylosyltransferase C terminal DUF87 PF01935.17 EGG24649.1 - 0.42 10.7 8.6 0.64 10.1 2.2 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain PGI PF00342.19 EGG24650.1 - 1.4e-240 799.0 0.2 1.6e-240 798.8 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Vps39_1 PF10366.9 EGG24650.1 - 0.11 12.8 0.6 0.98 9.7 0.1 2.7 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 HNH_2 PF13391.6 EGG24651.1 - 8.4e-08 32.2 0.5 1e-05 25.6 0.1 3.2 2 1 0 2 2 2 2 HNH endonuclease ABC2_membrane_3 PF12698.7 EGG24652.1 - 1.6e-50 172.2 56.4 6.9e-27 94.5 31.6 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 EGG24652.1 - 1.1e-48 165.2 0.0 1.8e-24 86.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGG24652.1 - 2.7e-14 53.7 0.7 6.2e-06 26.2 0.0 5.2 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG24652.1 - 2.2e-05 24.0 0.0 0.28 10.6 0.0 3.7 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGG24652.1 - 0.00055 20.1 0.1 0.66 10.3 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF4162 PF13732.6 EGG24652.1 - 0.00092 19.9 0.1 0.74 10.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 EGG24652.1 - 0.02 14.8 0.4 0.49 10.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EGG24652.1 - 0.032 14.0 5.9 0.32 10.8 0.1 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain SRP54 PF00448.22 EGG24652.1 - 0.041 13.5 0.7 8.6 5.9 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 EGG24652.1 - 0.081 12.8 0.0 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_15 PF13175.6 EGG24652.1 - 0.12 12.0 2.1 19 4.8 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain AAA_23 PF13476.6 EGG24652.1 - 2 8.8 9.5 2.3 8.6 0.2 2.8 3 0 0 3 3 3 0 AAA domain TIG PF01833.24 EGG24654.1 - 5.3e-06 26.4 1.4 1.3e-05 25.1 1.4 1.7 1 0 0 1 1 1 1 IPT/TIG domain TMEM154 PF15102.6 EGG24654.1 - 0.085 12.8 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family LRR_8 PF13855.6 EGG24656.1 - 1e-06 28.4 25.8 0.017 14.9 7.1 7.9 6 2 0 7 7 7 3 Leucine rich repeat EGF_2 PF07974.13 EGG24656.1 - 0.00028 21.2 58.4 0.061 13.7 9.3 4.9 4 0 0 4 4 4 3 EGF-like domain TIG PF01833.24 EGG24656.1 - 0.0042 17.1 11.9 0.0054 16.8 3.8 9.2 10 0 0 10 10 10 3 IPT/TIG domain DUF3844 PF12955.7 EGG24656.1 - 0.012 15.8 22.1 0.83 9.8 0.6 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3844) LRR_4 PF12799.7 EGG24656.1 - 0.76 10.3 0.0 0.19 12.2 6.5 12.3 14 3 2 16 16 16 0 Leucine Rich repeats (2 copies) Gly-zipper_Omp PF13488.6 EGG24656.1 - 1.2 9.2 10.6 0.63 10.1 1.9 2.4 2 0 0 2 2 2 0 Glycine zipper Adeno_E3_14_5 PF04834.12 EGG24657.1 - 0.011 16.3 0.2 0.042 14.4 0.2 2.0 1 0 0 1 1 1 0 Early E3 14.5 kDa protein DUF3844 PF12955.7 EGG24657.1 - 0.24 11.6 11.8 0.53 10.4 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3844) EGF_2 PF07974.13 EGG24657.1 - 0.55 10.7 34.4 0.48 10.8 12.5 2.8 2 0 0 2 2 2 0 EGF-like domain EGF_Tenascin PF18720.1 EGG24657.1 - 8.4 6.6 16.5 0.84 9.7 2.3 2.7 2 0 0 2 2 2 0 Tenascin EGF domain LRR_8 PF13855.6 EGG24658.1 - 6.1e-07 29.1 11.3 0.0001 22.0 1.2 6.1 5 1 1 6 6 6 2 Leucine rich repeat LRR_4 PF12799.7 EGG24658.1 - 0.0067 16.8 1.8 0.0067 16.8 1.8 7.8 7 2 3 10 10 10 2 Leucine Rich repeats (2 copies) DUF3844 PF12955.7 EGG24658.1 - 0.028 14.5 8.4 0.69 10.1 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) DUF3446 PF11928.8 EGG24658.1 - 0.33 11.3 9.9 4.1 7.8 6.5 3.1 2 0 0 2 2 2 0 Early growth response N-terminal domain EGF_2 PF07974.13 EGG24658.1 - 0.61 10.5 37.1 0.85 10.0 12.0 2.6 2 0 0 2 2 2 0 EGF-like domain LRR_1 PF00560.33 EGG24658.1 - 0.67 10.7 8.5 21 6.1 0.6 6.2 3 2 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 EGG24658.1 - 1.4 9.1 0.0 1.4 9.1 0.0 5.6 7 0 0 7 7 7 0 Leucine Rich repeat LRR_8 PF13855.6 EGG24659.1 - 3.4e-08 33.1 2.4 8.2e-05 22.3 0.5 4.5 4 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 EGG24659.1 - 0.0021 18.0 1.0 2.3 8.5 0.0 4.1 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 EGG24659.1 - 0.024 15.0 0.7 0.024 15.0 0.7 6.4 6 2 1 7 7 7 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGG24659.1 - 0.14 12.8 1.6 29 5.7 0.0 4.9 3 1 0 3 3 3 0 Leucine Rich Repeat EGF_2 PF07974.13 EGG24659.1 - 0.43 11.0 34.7 0.03 14.7 8.5 3.1 3 0 0 3 3 3 0 EGF-like domain DUF3844 PF12955.7 EGG24659.1 - 1.6 8.9 16.4 1.5 8.9 0.6 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3844) DUF3042 PF11240.8 EGG24659.1 - 3.6 7.7 5.3 9.3 6.4 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Laminin_EGF PF00053.24 EGG24659.1 - 8.5 6.6 16.6 2.6 8.3 4.0 3.2 2 0 0 2 2 2 0 Laminin EGF domain EGF_2 PF07974.13 EGG24660.1 - 0.00065 20.0 10.9 0.0013 19.1 10.9 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 EGG24660.1 - 0.45 11.2 9.0 1.1 10.0 9.0 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 EGG24660.1 - 0.86 9.7 9.0 2.2 8.4 9.0 1.8 1 0 0 1 1 1 0 Tenascin EGF domain EGF PF00008.27 EGG24660.1 - 7.8 6.9 17.9 0.67 10.3 13.1 1.7 2 0 0 2 2 2 0 EGF-like domain DUF3439 PF11921.8 EGG24661.1 - 0.014 15.3 17.7 0.023 14.7 9.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RabGAP-TBC PF00566.18 EGG24662.1 - 9.4e-54 182.3 1.7 1.4e-53 181.8 1.7 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MSV199 PF10553.9 EGG24662.1 - 0.023 14.9 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 MSV199 domain SR-25 PF10500.9 EGG24662.1 - 0.51 9.9 2.9 0.88 9.1 2.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ceramidase_alk PF04734.13 EGG24663.1 - 1.8e-221 736.2 0.6 2.2e-221 735.9 0.6 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EGG24663.1 - 3.4e-49 166.9 0.3 3.4e-49 166.9 0.3 1.8 2 0 0 2 2 2 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal RNase_P_p30 PF01876.16 EGG24664.1 - 2.5e-31 108.8 0.2 2.5e-31 108.8 0.2 1.3 2 0 0 2 2 2 1 RNase P subunit p30 Peptidase_S9 PF00326.21 EGG24665.1 - 0.05 13.1 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family TIG PF01833.24 EGG24667.1 - 8.4e-13 48.2 24.8 1e-07 31.9 3.6 4.1 4 1 0 4 4 4 3 IPT/TIG domain Lectin_C PF00059.21 EGG24667.1 - 0.025 15.3 1.3 0.41 11.4 0.0 2.8 3 0 0 3 3 3 0 Lectin C-type domain DUF3139 PF11337.8 EGG24667.1 - 0.082 13.6 3.2 0.36 11.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Sigma_reg_N PF13800.6 EGG24667.1 - 5.5 7.3 9.8 1.6 9.1 1.4 3.5 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF2481 PF10654.9 EGG24669.1 - 0.032 14.2 0.1 3.9 7.5 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2481) ubiquitin PF00240.23 EGG24669.1 - 0.048 13.4 0.1 0.092 12.5 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin family AAA_28 PF13521.6 EGG24670.1 - 0.011 16.0 0.1 0.02 15.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG24670.1 - 0.012 16.0 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EGG24670.1 - 0.023 14.9 0.5 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGG24670.1 - 0.035 14.2 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGG24670.1 - 0.16 12.5 0.6 0.55 10.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain TRI5 PF06330.11 EGG24670.1 - 0.18 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) ATP1G1_PLM_MAT8 PF02038.16 EGG24671.1 - 0.11 11.9 2.4 0.26 10.7 2.4 1.6 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Cytochrom_B558a PF05038.13 EGG24671.1 - 0.58 9.7 3.9 5.9 6.4 0.1 2.1 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Cg6151-P PF10233.9 EGG24671.1 - 1.1 9.6 13.5 2.3 8.5 13.5 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P DUF4175 PF13779.6 EGG24672.1 - 0.023 12.7 12.0 0.029 12.3 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CHASE3 PF05227.13 EGG24672.1 - 0.19 11.6 8.4 1.3 8.9 0.2 2.4 2 0 0 2 2 2 0 CHASE3 domain Dodecin PF07311.12 EGG24673.1 - 0.41 10.9 4.8 0.3 11.4 0.4 3.1 4 0 0 4 4 4 0 Dodecin Rpn9_C PF18261.1 EGG24673.1 - 3.4 7.3 7.6 0.36 10.4 1.1 2.7 3 0 0 3 3 3 0 Rpn9 C-terminal helix Atg14 PF10186.9 EGG24673.1 - 6.9 5.6 58.2 3.6 6.6 22.4 2.6 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Kinesin PF00225.23 EGG24674.1 - 2.1e-111 372.0 0.3 6.2e-111 370.5 0.3 1.9 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 EGG24674.1 - 8.4e-24 84.7 15.3 1.7e-20 74.0 3.7 3.4 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 EGG24674.1 - 5.5e-22 78.3 1.2 6e-21 74.9 0.1 2.8 2 0 0 2 2 2 1 Microtubule binding FHA PF00498.26 EGG24674.1 - 5e-08 33.2 2.0 1.4e-06 28.5 0.4 3.5 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 EGG24674.1 - 0.00072 19.8 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF3694 PF12473.8 EGG24674.1 - 0.027 15.1 0.1 0.86 10.2 0.0 3.0 2 1 0 2 2 2 0 Kinesin protein KIF1B PF12423.8 EGG24674.1 - 1.4 9.4 7.6 0.13 12.7 0.5 2.9 2 0 0 2 2 2 0 Kinesin protein 1B RhoGEF PF00621.20 EGG24675.1 - 3.8e-37 128.3 23.0 6.5e-37 127.5 19.3 3.1 2 1 0 2 2 2 1 RhoGEF domain PH PF00169.29 EGG24675.1 - 5.1e-13 49.4 0.2 5.1e-13 49.4 0.2 3.9 4 1 1 5 5 5 1 PH domain PH_8 PF15409.6 EGG24675.1 - 1.6e-05 25.0 0.2 4.5e-05 23.7 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EGG24675.1 - 2.2e-05 24.8 2.5 2.2e-05 24.8 2.5 5.2 5 1 0 5 5 5 1 Pleckstrin homology domain DUF3949 PF13133.6 EGG24675.1 - 0.18 12.3 1.1 0.51 10.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) DUF3439 PF11921.8 EGG24675.1 - 0.24 11.4 2.2 2.7 8.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RHD_DNA_bind PF00554.22 EGG24675.1 - 1.4 8.9 8.1 4.2 7.3 3.7 2.9 2 0 0 2 2 2 0 Rel homology DNA-binding domain protein_MS5 PF04776.12 EGG24676.1 - 0.0014 18.7 0.1 0.0041 17.2 0.0 1.8 2 0 0 2 2 2 1 Protein MS5 Nucleoside_tran PF01733.18 EGG24677.1 - 5.3e-34 118.0 25.7 5.4e-34 118.0 20.8 2.8 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 EGG24677.1 - 1.7e-12 47.0 23.2 1.8e-06 27.2 3.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2407_C PF13373.6 EGG24678.1 - 0.71 10.0 7.8 39 4.4 0.0 2.6 2 0 0 2 2 2 0 DUF2407 C-terminal domain FNIP PF05725.12 EGG24679.1 - 4.5e-193 625.3 60.3 2e-15 56.7 0.1 18.0 9 4 4 18 18 18 18 FNIP Repeat Pkinase PF00069.25 EGG24679.1 - 1.4e-21 77.1 3.8 3e-21 76.0 3.8 1.5 1 0 0 1 1 1 1 Protein kinase domain Phage_min_tail PF05939.13 EGG24679.1 - 3.5e-13 49.9 6.3 5.9 7.3 0.0 11.1 6 2 5 12 12 12 4 Phage minor tail protein Pkinase_Tyr PF07714.17 EGG24679.1 - 2.1e-07 30.5 1.8 0.0023 17.3 2.3 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase DUF3891 PF13030.6 EGG24680.1 - 0.054 13.3 0.7 0.063 13.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) RusA PF05866.11 EGG24680.1 - 0.071 13.7 0.0 0.088 13.4 0.0 1.2 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA RSN1_TM PF13967.6 EGG24680.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.5 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport AT_hook PF02178.19 EGG24681.1 - 0.0012 18.5 31.8 0.12 12.4 2.4 3.5 3 0 0 3 3 3 3 AT hook motif TIG PF01833.24 EGG24682.1 - 6.9e-16 58.1 18.1 6.6e-06 26.1 2.8 4.3 4 0 0 4 4 4 3 IPT/TIG domain EGF_2 PF07974.13 EGG24682.1 - 0.0035 17.7 9.7 0.013 15.9 9.7 2.0 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 EGG24682.1 - 8 6.9 10.8 30 5.0 10.8 2.0 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.24 EGG24683.1 - 3.1e-13 49.6 27.5 1.3e-07 31.5 2.5 4.5 4 0 0 4 4 4 3 IPT/TIG domain EGF_2 PF07974.13 EGG24683.1 - 0.0024 18.2 8.2 0.0082 16.5 8.2 1.9 1 0 0 1 1 1 1 EGF-like domain Lectin_C PF00059.21 EGG24683.1 - 0.016 15.9 8.0 0.021 15.5 0.3 3.3 4 0 0 4 4 4 0 Lectin C-type domain ABC_tran PF00005.27 EGG24684.1 - 1.1e-46 158.7 0.0 3.1e-23 82.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EGG24684.1 - 4.1e-46 157.7 58.5 4e-25 88.7 28.5 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EGG24684.1 - 1.5e-14 54.5 0.1 2.1e-06 27.8 0.0 4.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGG24684.1 - 8.7e-06 25.3 0.0 0.22 10.9 0.0 3.4 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGG24684.1 - 0.00063 19.9 0.0 0.89 9.8 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGG24684.1 - 0.0024 17.6 2.1 0.1 12.4 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain UCR_6-4kD PF08997.10 EGG24684.1 - 0.0041 17.0 0.4 0.016 15.1 0.4 2.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein DUF4162 PF13732.6 EGG24684.1 - 0.0045 17.7 0.1 0.58 10.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) Rad17 PF03215.15 EGG24684.1 - 0.01 15.8 0.0 0.39 10.6 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGG24684.1 - 0.022 14.7 0.4 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase SRP54 PF00448.22 EGG24684.1 - 0.024 14.3 3.5 1.7 8.2 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EGG24684.1 - 0.077 12.7 0.3 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGG24684.1 - 0.21 12.0 5.7 3.1 8.3 0.5 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EGG24684.1 - 0.69 9.6 2.6 32 4.1 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain eIF_4EBP PF05456.11 EGG24685.1 - 4.5e-25 87.8 4.0 5.5e-25 87.5 4.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) GTP_EFTU PF00009.27 EGG24686.1 - 9.1e-14 51.4 4.7 6.5e-09 35.6 0.0 2.7 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain p450 PF00067.22 EGG24688.1 - 6.7e-48 163.6 0.3 1.1e-47 162.9 0.3 1.3 1 0 0 1 1 1 1 Cytochrome P450 Tenui_NCP PF04876.12 EGG24688.1 - 0.021 14.4 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein DUF4820 PF16091.5 EGG24688.1 - 0.45 9.8 11.4 0.82 9.0 11.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Pox_Ag35 PF03286.14 EGG24688.1 - 0.86 9.4 10.2 1.6 8.5 10.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TIG PF01833.24 EGG24689.1 - 8.8e-14 51.4 22.9 6.4e-07 29.4 3.5 4.7 3 2 0 3 3 3 3 IPT/TIG domain Lectin_C PF00059.21 EGG24689.1 - 0.0094 16.7 0.8 0.27 12.0 0.1 2.6 2 0 0 2 2 2 1 Lectin C-type domain DUF2976 PF11190.8 EGG24689.1 - 0.021 14.6 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) CitMHS_2 PF16980.5 EGG24689.1 - 0.099 11.3 2.6 1 7.9 0.0 2.1 2 0 0 2 2 2 0 Putative citrate transport BatA PF07584.11 EGG24689.1 - 0.12 12.8 0.0 0.31 11.4 0.1 1.6 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal DUF4446 PF14584.6 EGG24690.1 - 0.17 11.9 3.4 0.26 11.2 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) ETRAMP PF09716.10 EGG24690.1 - 0.57 10.3 6.7 1.3 9.1 6.7 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MLANA PF14991.6 EGG24691.1 - 0.0067 16.7 0.0 0.028 14.7 0.0 2.1 1 0 0 1 1 1 1 Protein melan-A Wzy_C PF04932.15 EGG24691.1 - 0.054 13.1 7.0 0.45 10.1 0.0 3.3 3 1 0 3 3 3 0 O-Antigen ligase UAA PF08449.11 EGG24692.1 - 8.5e-95 317.4 29.7 1.4e-94 316.7 29.7 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 EGG24692.1 - 1.1e-06 28.2 23.6 2.6e-05 23.7 23.6 2.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGG24692.1 - 1.5e-06 28.5 33.2 0.002 18.3 13.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family UPF0029 PF01205.19 EGG24694.1 - 4.7e-31 107.2 0.0 7.9e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EGG24694.1 - 3.5e-13 49.8 0.2 3.5e-13 49.8 0.2 2.3 2 1 0 2 2 2 1 RWD domain KOG2701 PF09762.9 EGG24694.1 - 0.066 13.4 1.0 0.32 11.2 0.2 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) PAS_3 PF08447.12 EGG24694.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 PAS fold RICTOR_N PF14664.6 EGG24696.1 - 0.0075 15.3 0.8 0.016 14.2 0.8 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term DUF1860 PF08949.10 EGG24697.1 - 0.033 13.9 0.1 0.057 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) DUF4611 PF15387.6 EGG24699.1 - 0.052 13.8 3.0 0.065 13.4 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Ago_hook PF10427.9 EGG24700.1 - 0.15 12.6 1.6 0.25 11.9 0.5 1.7 2 0 0 2 2 2 0 Argonaute hook IZUMO PF15005.6 EGG24701.1 - 0.067 13.7 3.2 0.34 11.4 3.0 1.9 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated OSCP PF00213.18 EGG24701.1 - 0.087 12.9 2.4 0.14 12.3 2.4 1.3 1 1 0 1 1 1 0 ATP synthase delta (OSCP) subunit FAM150 PF15129.6 EGG24701.1 - 0.09 12.9 0.8 6.4 6.9 0.3 2.2 1 1 1 2 2 2 0 FAM150 family RapH_N PF18801.1 EGG24701.1 - 0.27 11.4 3.2 15 5.7 1.6 2.3 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal DUF3947 PF13135.6 EGG24701.1 - 0.39 10.9 2.8 0.68 10.2 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) SAM_2 PF07647.17 EGG24705.1 - 1.3e-05 25.2 0.9 1.9e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGG24705.1 - 0.021 15.3 0.4 0.037 14.5 0.0 1.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 EGG24705.1 - 0.11 12.8 1.4 0.14 12.4 0.1 1.8 2 0 0 2 2 2 0 Ste50p, sterile alpha motif tRNA-synt_1 PF00133.22 EGG24706.1 - 1.8e-60 204.8 4.3 9.5e-37 126.5 4.9 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EGG24706.1 - 1.6e-31 109.3 0.0 3.3e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EGG24706.1 - 9.7e-29 100.3 1.3 9.5e-21 74.0 0.0 4.2 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGG24706.1 - 3.7e-08 33.5 0.0 8.4e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGG24706.1 - 0.00012 21.6 0.0 0.23 10.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EGG24706.1 - 0.0048 15.9 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) Zn-ribbon_8 PF09723.10 EGG24706.1 - 0.36 11.0 1.7 1.6 8.9 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 EGG24706.1 - 1.1 8.8 7.2 1.2 8.7 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Ank_2 PF12796.7 EGG24707.1 - 6.8e-12 45.8 0.7 2.9e-05 24.6 0.1 3.2 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG24707.1 - 2.6e-08 33.5 1.4 0.0059 17.0 0.1 5.7 5 1 1 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 EGG24707.1 - 2.2e-06 28.1 1.5 0.00059 20.4 0.2 4.5 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24707.1 - 0.0017 18.6 0.4 16 6.0 0.0 4.7 3 2 2 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 EGG24707.1 - 0.0077 16.6 0.7 5 7.7 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat SWIB PF02201.18 EGG24708.1 - 2.6e-18 65.7 0.6 5.7e-18 64.6 0.6 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DOT1 PF08123.13 EGG24708.1 - 0.0026 17.3 0.1 0.005 16.4 0.1 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 YEATS PF03366.16 EGG24708.1 - 0.016 15.1 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 YEATS family Mgm101p PF06420.12 EGG24709.1 - 1.7e-73 245.7 0.0 2.8e-73 245.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 TIG PF01833.24 EGG24711.1 - 2.6e-12 46.6 27.9 3.5e-07 30.2 2.7 4.2 4 1 0 4 4 4 3 IPT/TIG domain Baculo_11_kDa PF06143.11 EGG24711.1 - 0.22 11.1 1.7 0.48 10.0 1.7 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Lectin_C PF00059.21 EGG24711.1 - 0.38 11.5 2.9 1.7 9.4 0.1 2.8 3 0 0 3 3 3 0 Lectin C-type domain Steroid_dh PF02544.16 EGG24712.1 - 5.3e-39 133.6 1.5 5.3e-39 133.6 1.5 1.8 3 0 0 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EGG24712.1 - 8.1e-07 28.8 1.4 1.2e-06 28.2 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ubiquitin PF00240.23 EGG24712.1 - 2e-05 24.2 1.0 0.00027 20.6 1.0 2.1 1 1 0 1 1 1 1 Ubiquitin family PEMT PF04191.13 EGG24712.1 - 0.00026 21.3 1.1 0.00066 20.0 1.1 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase AcrZ PF10766.9 EGG24712.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ DUF4504 PF14953.6 EGG24712.1 - 0.015 14.7 0.1 0.022 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) Ubiquitin_2 PF14560.6 EGG24712.1 - 0.09 13.2 0.9 0.54 10.8 0.9 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain Orai-1 PF07856.12 EGG24712.1 - 0.1 12.2 0.6 0.23 11.2 0.6 1.5 1 0 0 1 1 1 0 Mediator of CRAC channel activity RseC_MucC PF04246.12 EGG24712.1 - 0.28 11.1 0.7 4.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ATP-synt_A PF00119.20 EGG24712.1 - 1.1 9.2 7.6 2.9 7.8 7.6 1.9 1 1 0 1 1 1 0 ATP synthase A chain LRRNT PF01462.18 EGG24713.1 - 0.28 10.9 4.8 0.5 10.1 0.4 2.8 3 1 0 3 3 3 0 Leucine rich repeat N-terminal domain UCH PF00443.29 EGG24714.1 - 3.2e-47 161.2 12.2 5.7e-47 160.4 12.2 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG24714.1 - 4.9e-23 82.2 20.6 2.8e-22 79.7 20.6 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3175 PF11373.8 EGG24714.1 - 0.042 14.0 2.4 0.055 13.6 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3175) dsDNA_bind PF01984.20 EGG24714.1 - 0.29 11.4 7.3 0.8 10.0 7.3 1.7 1 0 0 1 1 1 0 Double-stranded DNA-binding domain DUF4578 PF15147.6 EGG24714.1 - 0.59 11.0 7.5 0.18 12.7 4.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) Mucin PF01456.17 EGG24715.1 - 2 8.4 15.1 2.3 8.2 3.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Sporozoite_P67 PF05642.11 EGG24715.1 - 3.2 5.7 27.4 0.77 7.8 0.1 2.8 3 0 0 3 3 3 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 EGG24715.1 - 3.7 5.5 22.0 0.48 8.5 11.8 2.2 2 0 0 2 2 2 0 DNA polymerase phi DUF2457 PF10446.9 EGG24716.1 - 0.43 9.7 16.5 1.1 8.3 16.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) tRNA-synt_1e PF01406.19 EGG24717.1 - 3.9e-129 430.3 0.5 3.9e-129 430.3 0.5 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGG24717.1 - 3.8e-12 45.7 8.6 9.4e-07 27.9 0.2 2.9 4 0 0 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGG24717.1 - 3.4e-05 22.3 4.4 0.0021 16.4 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) AAA-ATPase_like PF09820.9 EGG24717.1 - 0.00058 19.4 0.7 0.00058 19.4 0.7 2.0 2 1 0 2 2 2 1 Predicted AAA-ATPase tRNA-synt_1c PF00749.21 EGG24717.1 - 0.0097 14.8 1.3 0.025 13.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain RXLR PF16810.5 EGG24717.1 - 0.61 10.5 4.3 1.9 8.9 4.3 1.9 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity TIG PF01833.24 EGG24718.1 - 2.5e-05 24.2 2.2 2.5e-05 24.2 2.2 2.9 3 0 0 3 3 3 2 IPT/TIG domain EGF_2 PF07974.13 EGG24718.1 - 0.0021 18.4 7.5 0.0021 18.4 7.5 1.9 2 0 0 2 2 2 1 EGF-like domain TIG PF01833.24 EGG24719.1 - 3.3e-07 30.3 1.6 6.3e-07 29.4 1.6 1.4 1 0 0 1 1 1 1 IPT/TIG domain TPT PF03151.16 EGG24720.1 - 3.7e-12 46.2 18.9 4.8e-12 45.8 18.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Pox_I5 PF04713.12 EGG24720.1 - 5.4 7.1 8.6 0.42 10.7 1.4 2.8 2 1 1 3 3 3 0 Poxvirus protein I5 HMG-CoA_red PF00368.18 EGG24721.1 - 3.2e-91 306.1 2.9 3.2e-91 306.1 2.9 1.3 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Ank_4 PF13637.6 EGG24722.1 - 5.4e-19 68.3 0.8 1.8e-08 34.7 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24722.1 - 9.1e-19 67.3 0.9 7.6e-10 38.8 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG24722.1 - 1.9e-18 66.8 1.3 9.9e-17 61.3 1.3 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGG24722.1 - 7.6e-17 60.9 0.3 7.1e-08 32.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGG24722.1 - 8e-13 47.3 0.2 5.1e-05 23.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat CH PF00307.31 EGG24723.1 - 4.4e-43 145.9 0.1 2.1e-22 79.3 0.2 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain Cortex-I_coil PF09304.10 EGG24723.1 - 5.2e-40 136.0 25.5 5.2e-40 136.0 25.5 2.9 2 1 1 3 3 3 1 Cortexillin I, coiled coil CAMSAP_CH PF11971.8 EGG24723.1 - 0.00047 19.9 0.0 1.8 8.5 0.0 2.9 2 1 0 2 2 2 2 CAMSAP CH domain DUF4635 PF15466.6 EGG24723.1 - 0.043 13.3 3.7 0.13 11.7 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) DUF2730 PF10805.8 EGG24723.1 - 1.9 8.6 8.8 0.47 10.6 3.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) LMBR1 PF04791.16 EGG24723.1 - 4 6.2 5.3 6.2 5.6 5.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 EGG24723.1 - 4 7.5 5.9 1.9 8.5 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BSD PF03909.17 EGG24724.1 - 6.5e-17 61.3 0.7 3e-12 46.3 0.5 2.9 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 EGG24724.1 - 2.4e-16 59.8 0.3 2.4e-16 59.8 0.3 2.0 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Vps36_ESCRT-II PF11605.8 EGG24724.1 - 0.0027 17.9 0.8 0.011 15.9 0.1 2.3 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 RskA PF10099.9 EGG24724.1 - 0.0037 17.6 3.6 0.0057 17.0 3.6 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA BBL5 PF07289.11 EGG24724.1 - 0.0051 15.9 0.2 0.011 14.8 0.2 1.5 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein NUC173 PF08161.12 EGG24724.1 - 0.056 13.1 3.8 0.11 12.1 0.1 2.9 4 0 0 4 4 4 0 NUC173 domain Gram_pos_anchor PF00746.21 EGG24724.1 - 0.11 12.5 1.2 0.22 11.5 1.2 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif NTS_2 PF15448.6 EGG24725.1 - 0.35 11.3 4.0 3 8.3 0.6 3.1 3 0 0 3 3 3 0 N-terminal segments of P. falciparum erythrocyte membrane protein AIM24 PF01987.17 EGG24726.1 - 3.8e-30 105.2 0.1 3.4e-17 62.9 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial biogenesis AIM24 KBP_C PF12309.8 EGG24726.1 - 0.0012 18.4 0.9 0.0016 18.1 0.9 1.1 1 0 0 1 1 1 1 KIF-1 binding protein C terminal Presenilin PF01080.17 EGG24726.1 - 0.77 8.5 4.3 0.98 8.1 4.3 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGG24726.1 - 1.4 7.2 11.3 1.7 6.8 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF334 PF03904.13 EGG24726.1 - 2.2 7.7 6.2 3.5 7.1 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Erf4 PF10256.9 EGG24727.1 - 3.5e-05 23.9 0.3 0.00016 21.8 0.0 2.2 1 1 1 2 2 2 1 Golgin subfamily A member 7/ERF4 family ATP-synt_I PF03899.15 EGG24727.1 - 0.0013 19.0 0.8 0.0019 18.5 0.8 1.2 1 0 0 1 1 1 1 ATP synthase I chain DUF2809 PF10990.8 EGG24727.1 - 0.035 14.8 0.1 0.067 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) DUF2985 PF11204.8 EGG24727.1 - 1.1 9.4 4.1 8.5 6.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) Erf4 PF10256.9 EGG24729.1 - 2.4e-05 24.4 0.8 7.3e-05 22.9 0.8 1.9 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TIG PF01833.24 EGG24730.1 - 1.1e-07 31.8 19.8 5.6e-05 23.1 2.2 4.3 3 1 0 3 3 3 3 IPT/TIG domain EGF_2 PF07974.13 EGG24730.1 - 0.0073 16.7 9.3 0.023 15.1 9.3 1.8 1 0 0 1 1 1 1 EGF-like domain Erf4 PF10256.9 EGG24730.1 - 0.052 13.7 0.1 0.16 12.1 0.1 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family VKOR PF07884.14 EGG24730.1 - 0.32 11.2 3.8 0.11 12.6 0.3 2.1 2 0 0 2 2 2 0 Vitamin K epoxide reductase family SUIM_assoc PF16619.5 EGG24733.1 - 0.032 14.3 2.6 0.032 14.3 2.6 2.0 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 YajC PF02699.15 EGG24733.1 - 0.12 12.3 0.6 0.21 11.5 0.6 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit DUF2232 PF09991.9 EGG24733.1 - 0.39 9.9 2.4 0.46 9.6 2.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) RicinB_lectin_2 PF14200.6 EGG24737.1 - 0.0062 17.2 1.9 1.6 9.5 0.4 3.3 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like EF-hand_12 PF17901.1 EGG24738.1 - 9.3e-42 141.4 0.7 3.1e-41 139.7 0.7 2.0 1 0 0 1 1 1 1 EF-hand fold domain STATa_Ig PF18214.1 EGG24738.1 - 5.4e-19 68.4 0.9 5.4e-19 68.4 0.9 2.1 2 0 0 2 2 2 1 STATa Immunoglobulin-like domain SH2 PF00017.24 EGG24738.1 - 5.9e-09 35.9 0.0 2e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Dict-STAT-coil PF09267.10 EGG24738.1 - 0.00053 20.4 3.8 0.00053 20.4 3.8 3.0 3 0 0 3 3 3 1 Dictyostelium STAT, coiled coil DUF1931 PF09123.11 EGG24738.1 - 0.013 15.6 0.3 0.039 14.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Ribosomal_L3 PF00297.22 EGG24739.1 - 3.8e-167 555.9 7.6 4.8e-167 555.6 7.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 SBE2 PF17076.5 EGG24739.1 - 0.0019 16.5 0.1 0.0027 16.0 0.1 1.1 1 0 0 1 1 1 1 SBE2, cell-wall formation Macoilin PF09726.9 EGG24740.1 - 0.0044 15.7 11.5 0.006 15.2 11.5 1.1 1 0 0 1 1 1 1 Macoilin family DUF3439 PF11921.8 EGG24741.1 - 1.7 8.6 11.2 0.74 9.8 3.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGG24741.1 - 8.4 6.4 18.3 6 6.9 11.3 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein TIG PF01833.24 EGG24742.1 - 0.0001 22.3 1.6 0.0001 22.3 1.6 3.0 3 0 0 3 3 3 1 IPT/TIG domain Sld5 PF05916.11 EGG24742.1 - 0.00016 22.1 1.1 0.00054 20.4 0.1 2.2 2 0 0 2 2 2 1 GINS complex protein Lectin_C PF00059.21 EGG24742.1 - 0.095 13.4 1.8 0.58 10.9 0.1 3.0 3 0 0 3 3 3 0 Lectin C-type domain MSA-2c PF12238.8 EGG24744.1 - 0.072 13.1 5.9 0.097 12.7 5.9 1.3 1 1 0 1 1 1 0 Merozoite surface antigen 2c Lipin_mid PF16876.5 EGG24744.1 - 0.093 12.9 0.3 0.12 12.5 0.3 1.2 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Clr2 PF10383.9 EGG24744.1 - 0.23 12.2 1.0 0.32 11.8 1.0 1.4 1 1 0 1 1 1 0 Transcription-silencing protein Clr2 ubiquitin PF00240.23 EGG24745.1 - 1e-12 47.6 0.0 5.6e-12 45.2 0.0 2.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGG24745.1 - 9.5e-09 35.0 0.0 7.7e-08 32.1 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like VWA_2 PF13519.6 EGG24745.1 - 2.6e-06 28.0 0.0 1.3e-05 25.8 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Ras PF00071.22 EGG24745.1 - 0.00038 20.1 0.2 0.0015 18.1 0.0 2.0 2 0 0 2 2 2 1 Ras family FtsH_ext PF06480.15 EGG24745.1 - 0.042 14.2 1.6 1.3 9.4 0.3 2.7 2 0 0 2 2 2 0 FtsH Extracellular INO80_Ies4 PF08193.11 EGG24745.1 - 0.044 13.8 0.2 0.044 13.8 0.2 2.3 2 0 0 2 2 2 0 INO80 complex subunit Ies4 SLAC1 PF03595.17 EGG24746.1 - 4.9e-14 52.3 21.1 1.9e-09 37.2 6.8 2.1 1 1 1 2 2 2 2 Voltage-dependent anion channel DUF2243 PF10002.9 EGG24746.1 - 0.079 13.1 0.3 0.24 11.5 0.3 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2243) GRAM PF02893.20 EGG24747.1 - 4.4e-09 36.2 0.8 6.5e-09 35.7 0.2 1.5 2 0 0 2 2 2 1 GRAM domain NRBF2 PF08961.10 EGG24747.1 - 5.6e-05 22.8 2.1 7.9e-05 22.3 2.1 1.1 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator Cnn_1N PF07989.11 EGG24747.1 - 0.0049 17.0 2.9 0.0093 16.1 2.9 1.5 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 VIT PF08487.10 EGG24747.1 - 0.015 15.5 0.1 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain ZapB PF06005.12 EGG24747.1 - 0.09 13.2 8.9 0.12 12.8 4.3 2.3 1 1 1 2 2 2 0 Cell division protein ZapB Cob_adeno_trans PF01923.18 EGG24747.1 - 0.096 12.8 0.4 0.25 11.5 0.4 1.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase YabA PF06156.13 EGG24747.1 - 0.1 13.3 4.8 0.094 13.4 3.3 1.8 2 0 0 2 2 2 0 Initiation control protein YabA ADIP PF11559.8 EGG24747.1 - 0.13 12.4 9.9 0.47 10.5 7.6 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cdh1_DBD_1 PF18196.1 EGG24747.1 - 0.28 11.5 4.3 0.21 11.9 2.3 1.8 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Atg14 PF10186.9 EGG24747.1 - 0.35 9.9 6.0 0.51 9.4 6.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TSC22 PF01166.18 EGG24747.1 - 0.53 10.6 3.3 0.68 10.3 1.9 1.9 1 1 1 2 2 2 0 TSC-22/dip/bun family CtIP_N PF10482.9 EGG24747.1 - 0.7 10.0 6.1 0.53 10.3 4.0 1.9 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DivIC PF04977.15 EGG24747.1 - 4.1 7.2 9.8 0.61 9.9 2.9 2.6 1 1 2 3 3 3 0 Septum formation initiator ANAPC4_WD40 PF12894.7 EGG24748.1 - 7.1e-07 29.4 0.2 0.14 12.5 0.1 4.2 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BUD22 PF09073.10 EGG24748.1 - 0.0016 17.9 26.8 0.0022 17.4 26.8 1.1 1 0 0 1 1 1 1 BUD22 WD40_like PF17005.5 EGG24748.1 - 0.0048 16.3 0.1 0.74 9.1 0.0 3.0 3 0 0 3 3 3 1 WD40-like domain WD40 PF00400.32 EGG24748.1 - 0.0058 17.5 0.0 0.047 14.6 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat PQQ_2 PF13360.6 EGG24748.1 - 0.088 12.4 0.1 0.34 10.4 0.1 1.9 1 1 0 1 1 1 0 PQQ-like domain SDA1 PF05285.12 EGG24748.1 - 0.53 9.7 26.2 0.82 9.0 26.2 1.2 1 0 0 1 1 1 0 SDA1 CCDC53 PF10152.9 EGG24748.1 - 4.9 7.6 12.2 21 5.5 0.0 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CDC45 PF02724.14 EGG24748.1 - 5.1 5.3 14.9 7.6 4.7 14.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 EGG24748.1 - 7.4 5.6 15.0 14 4.7 15.0 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Thioredoxin PF00085.20 EGG24750.1 - 0.00047 20.1 0.1 0.00055 19.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.6 EGG24750.1 - 0.021 15.0 0.1 0.028 14.6 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin Alpha-amylase_C PF02806.18 EGG24751.1 - 1.3e-23 83.3 0.0 1.5e-22 79.8 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EGG24751.1 - 4.2e-17 62.3 0.3 1e-16 61.1 0.3 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EGG24751.1 - 1.1e-14 54.8 0.1 2.8e-12 46.9 0.2 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EGG24751.1 - 0.027 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain RasGAP PF00616.19 EGG24753.1 - 1.6e-24 86.8 0.0 3.2e-12 46.6 0.0 3.3 3 0 0 3 3 3 2 GTPase-activator protein for Ras-like GTPase DUF547 PF04784.14 EGG24753.1 - 4.3e-23 81.7 0.7 1.3e-22 80.1 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function, DUF547 BLOC1_2 PF10046.9 EGG24753.1 - 0.046 14.0 1.8 0.94 9.8 0.2 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SRP14 PF02290.15 EGG24756.1 - 4.2e-21 75.1 0.1 6.5e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein DUF365 PF04033.12 EGG24756.1 - 0.012 15.8 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF365) DUF370 PF04025.12 EGG24756.1 - 0.097 12.8 0.1 0.21 11.8 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF370) EF_assoc_2 PF08356.12 EGG24756.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 EF hand associated CSN8_PSD8_EIF3K PF10075.9 EGG24757.1 - 8.4e-27 93.9 0.0 3.1e-26 92.1 0.0 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EGG24757.1 - 0.00095 18.6 0.2 0.0013 18.2 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP family DUF953 PF06110.11 EGG24758.1 - 1.7e-21 76.0 0.1 2e-21 75.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 EGG24758.1 - 0.00021 21.0 0.1 0.00044 20.0 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin DUF2387 PF09526.10 EGG24758.1 - 0.0028 17.8 0.1 0.0054 16.9 0.1 1.5 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) Thioredoxin PF00085.20 EGG24758.1 - 0.0077 16.2 0.2 0.021 14.8 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin zf-FPG_IleRS PF06827.14 EGG24758.1 - 0.038 13.8 0.1 0.089 12.7 0.1 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Elf1 PF05129.13 EGG24758.1 - 0.05 13.7 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like TIG PF01833.24 EGG24759.1 - 8.7e-06 25.7 2.0 8.7e-06 25.7 2.0 2.9 3 0 0 3 3 3 1 IPT/TIG domain EGF_2 PF07974.13 EGG24759.1 - 0.0045 17.3 9.0 0.0045 17.3 9.0 1.9 2 0 0 2 2 2 1 EGF-like domain CMAS PF02353.20 EGG24760.1 - 0.066 12.5 0.0 0.084 12.2 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF4530 PF15039.6 EGG24761.1 - 0.081 13.1 0.4 0.21 11.7 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) ZapB PF06005.12 EGG24761.1 - 0.45 11.0 8.5 0.048 14.1 2.7 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Nefa_Nip30_N PF10187.9 EGG24761.1 - 3 8.2 11.4 0.81 10.1 2.0 3.4 3 0 0 3 3 3 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Mucin PF01456.17 EGG24761.1 - 4.5 7.3 26.2 4.7 7.2 11.0 3.2 3 0 0 3 3 3 0 Mucin-like glycoprotein 2-Hacid_dh_C PF02826.19 EGG24763.1 - 2.5e-54 183.3 0.0 3.8e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGG24763.1 - 1.6e-22 79.6 0.0 2.5e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGG24763.1 - 6.1e-07 29.7 0.2 1.3e-06 28.7 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EGG24763.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ADH_zinc_N PF00107.26 EGG24763.1 - 0.051 13.6 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.21 EGG24763.1 - 0.054 13.6 0.7 0.12 12.4 0.7 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TIG PF01833.24 EGG24764.1 - 3.6e-12 46.2 23.6 2.1e-05 24.5 1.7 4.0 3 0 0 3 3 3 3 IPT/TIG domain EGF_2 PF07974.13 EGG24764.1 - 0.002 18.5 8.9 0.0084 16.5 8.9 2.1 1 0 0 1 1 1 1 EGF-like domain Pkinase PF00069.25 EGG24765.1 - 6.6e-50 169.9 0.0 2.5e-49 168.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG24765.1 - 1.7e-19 70.1 0.0 3.9e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG24765.1 - 0.00019 20.4 0.0 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGG24765.1 - 0.0045 16.1 0.1 0.0071 15.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EGG24765.1 - 0.0095 15.9 0.1 0.044 13.7 0.3 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGG24765.1 - 0.021 13.8 0.1 0.04 12.9 0.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EGG24765.1 - 0.028 13.8 0.0 0.14 11.4 0.0 2.0 2 1 1 3 3 3 0 Kinase-like Choline_kinase PF01633.20 EGG24765.1 - 0.088 12.4 0.4 0.24 11.0 0.4 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EGG24765.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ThiF PF00899.21 EGG24766.1 - 4.6e-91 304.5 0.1 5.2e-65 219.2 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGG24766.1 - 3.4e-74 249.9 5.8 3.4e-74 249.9 5.8 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EGG24766.1 - 1.6e-28 98.6 0.6 1.4e-27 95.7 0.5 2.5 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EGG24766.1 - 2.3e-15 56.5 0.2 5.8e-15 55.2 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 EGG24766.1 - 8.1e-11 42.5 0.9 2.8e-10 40.8 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin fold domain Nop14 PF04147.12 EGG24767.1 - 0.00044 18.6 17.1 0.00048 18.5 17.1 1.0 1 0 0 1 1 1 1 Nop14-like family IFT57 PF10498.9 EGG24767.1 - 0.0059 15.6 9.0 0.0069 15.4 9.0 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 CDC45 PF02724.14 EGG24767.1 - 0.027 12.8 21.5 0.034 12.5 21.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 EGG24767.1 - 0.14 11.2 34.2 0.19 10.8 34.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 EGG24767.1 - 0.25 10.8 23.2 0.3 10.5 23.2 1.1 1 0 0 1 1 1 0 SDA1 Utp14 PF04615.13 EGG24767.1 - 0.81 8.2 20.9 0.95 8.0 20.9 1.1 1 0 0 1 1 1 0 Utp14 protein Apt1 PF10351.9 EGG24767.1 - 1.2 7.9 14.2 1.4 7.6 14.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain YL1 PF05764.13 EGG24767.1 - 2.1 8.4 23.3 2.7 8.0 23.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein PI3K_1B_p101 PF10486.9 EGG24767.1 - 5.1 4.8 10.8 6 4.5 10.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Lin-8 PF03353.15 EGG24767.1 - 6.4 6.2 13.1 7.9 5.9 13.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BUD22 PF09073.10 EGG24767.1 - 7.1 5.9 24.0 8.7 5.6 24.0 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 EGG24767.1 - 9.3 4.2 35.5 12 3.9 35.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DEAD PF00270.29 EGG24768.1 - 2.3e-31 108.9 1.7 3.7e-31 108.2 0.5 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG24768.1 - 4.2e-21 75.4 0.1 1.8e-20 73.3 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGG24768.1 - 0.021 15.1 0.8 0.25 11.6 0.5 2.9 2 1 0 2 2 2 0 AAA domain CDC45 PF02724.14 EGG24769.1 - 0.39 9.0 11.8 0.58 8.4 11.8 1.4 1 0 0 1 1 1 0 CDC45-like protein AAA_6 PF12774.7 EGG24770.1 - 0.0048 15.9 0.1 0.0048 15.9 0.1 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region PTEN_C2 PF10409.9 EGG24771.1 - 1.2e-19 70.4 0.1 1.2e-19 70.4 0.1 1.6 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein TFIIA PF03153.13 EGG24771.1 - 3.2 7.7 32.3 4.3 7.2 32.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cmc1 PF08583.10 EGG24772.1 - 7.2e-17 61.2 5.9 1e-16 60.7 5.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 EGG24772.1 - 0.0023 18.0 4.5 0.0046 17.1 4.5 1.5 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 EGG24772.1 - 0.0078 15.9 0.9 0.012 15.3 0.9 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 EGG24772.1 - 0.01 15.8 3.1 0.019 14.9 3.1 1.5 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Ribosomal_S24e PF01282.19 EGG24773.1 - 1.1e-29 102.1 0.1 1.1e-29 102.1 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S24e Ank_2 PF12796.7 EGG24774.1 - 3.7e-32 110.7 0.4 2.1e-13 50.7 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24774.1 - 1.7e-30 105.0 9.8 5.5e-10 39.6 0.2 5.4 1 1 5 6 6 6 5 Ankyrin repeats (many copies) DHHC PF01529.20 EGG24774.1 - 1.3e-28 99.8 3.6 1.3e-28 99.8 3.6 2.8 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_3 PF13606.6 EGG24774.1 - 5.1e-27 91.0 0.3 0.00069 19.9 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 EGG24774.1 - 1.3e-26 91.8 0.2 2.4e-05 24.5 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EGG24774.1 - 2.1e-25 88.5 4.3 1e-09 38.5 0.0 6.3 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG24776.1 - 1.2e-05 25.7 0.0 0.1 13.2 0.0 4.1 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24776.1 - 1.6e-05 25.3 1.6 0.08 13.6 0.1 5.5 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24776.1 - 0.0058 17.0 0.2 1.9e+02 3.2 0.0 5.9 6 0 0 6 6 6 0 Ankyrin repeat Histone_H2A_C PF16211.5 EGG24776.1 - 0.32 10.8 0.8 3.4 7.5 0.1 2.8 3 0 0 3 3 3 0 C-terminus of histone H2A DUF3447 PF11929.8 EGG24776.1 - 2.4 8.2 11.2 1.3 9.0 1.0 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF3447) DUF1296 PF06972.11 EGG24777.1 - 0.035 14.2 1.1 11 6.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) DAGAT PF03982.13 EGG24778.1 - 0.0098 14.8 0.1 0.3 10.0 0.1 2.2 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Ank_2 PF12796.7 EGG24779.1 - 0.00046 20.7 0.0 0.0015 19.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24779.1 - 0.0023 18.5 1.3 0.057 14.0 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24779.1 - 0.0034 17.7 0.1 0.064 13.6 0.1 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24779.1 - 0.0099 16.3 0.1 0.65 10.7 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat DUF4864 PF16156.5 EGG24779.1 - 0.043 14.5 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) RRM_1 PF00076.22 EGG24780.1 - 8.5e-17 60.7 0.1 1.8e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 EGG24780.1 - 1.8e-07 31.7 0.1 0.001 19.6 0.0 4.0 3 1 0 4 4 4 1 Ankyrin repeats (3 copies) zf-CCHC PF00098.23 EGG24780.1 - 2e-07 30.8 3.0 4.8e-07 29.6 3.0 1.7 1 0 0 1 1 1 1 Zinc knuckle Ank_5 PF13857.6 EGG24780.1 - 0.0012 19.1 0.2 0.071 13.5 0.1 3.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24780.1 - 0.0061 17.0 0.6 9.4 7.2 0.0 4.7 3 1 1 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EGG24780.1 - 0.0094 16.5 0.0 60 4.4 0.0 4.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) zf-CCHC_2 PF13696.6 EGG24780.1 - 0.014 15.2 1.6 0.014 15.2 1.6 2.2 3 0 0 3 3 3 0 Zinc knuckle CDtoxinA PF03498.14 EGG24780.1 - 0.023 14.3 0.0 0.075 12.6 0.0 1.8 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain zf-CCHC_3 PF13917.6 EGG24780.1 - 4.3 7.4 10.1 0.048 13.6 1.2 2.2 2 0 0 2 2 2 0 Zinc knuckle Peptidase_M41 PF01434.18 EGG24781.1 - 6.3e-66 221.9 0.1 6.3e-66 221.9 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 EGG24781.1 - 9e-44 149.1 0.4 3e-43 147.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RWD PF05773.22 EGG24781.1 - 9.4e-15 54.9 0.5 9.4e-15 54.9 0.5 2.9 3 1 0 3 3 1 1 RWD domain AAA_lid_3 PF17862.1 EGG24781.1 - 6.9e-12 45.0 0.0 1.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_17 PF13207.6 EGG24781.1 - 0.00046 20.6 0.0 0.01 16.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGG24781.1 - 0.0006 19.8 0.0 0.0018 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IBR PF01485.21 EGG24781.1 - 0.0056 16.9 6.7 0.0056 16.9 6.7 2.6 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain RuvB_N PF05496.12 EGG24781.1 - 0.0068 16.2 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGG24781.1 - 0.0072 16.7 0.2 0.27 11.6 0.1 2.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGG24781.1 - 0.0092 16.3 0.1 0.2 11.9 0.1 2.7 1 1 0 1 1 1 1 AAA domain DUF3439 PF11921.8 EGG24781.1 - 0.051 13.5 14.9 0.19 11.7 3.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) IstB_IS21 PF01695.17 EGG24781.1 - 0.07 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Trypan_PARP PF05887.11 EGG24781.1 - 0.099 12.6 2.7 0.36 10.8 2.7 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TIP49 PF06068.13 EGG24781.1 - 0.13 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 EGG24781.1 - 0.14 11.5 0.1 0.31 10.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EGG24781.1 - 0.22 11.6 0.0 0.22 11.6 0.0 2.8 3 1 0 3 3 2 0 AAA domain (Cdc48 subfamily) zinc_ribbon_9 PF14369.6 EGG24781.1 - 0.43 10.9 3.9 0.77 10.1 0.1 3.0 1 1 1 2 2 2 0 zinc-ribbon RR_TM4-6 PF06459.12 EGG24781.1 - 0.73 9.6 15.7 2.3 8.0 15.7 1.9 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_18 PF13238.6 EGG24781.1 - 2.9 8.4 6.8 5.8 7.5 0.0 4.0 4 0 0 4 4 3 0 AAA domain Peroxin-13_N PF04088.13 EGG24781.1 - 7.8 6.8 10.8 2.7e+02 1.8 10.7 3.6 3 1 0 3 3 3 0 Peroxin 13, N-terminal region Pex14_N PF04695.13 EGG24781.1 - 10 6.8 28.1 0.035 14.8 4.7 3.9 3 1 1 4 4 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UAA PF08449.11 EGG24782.1 - 1.1e-26 93.7 26.8 1.8e-26 93.1 26.0 1.7 1 1 1 2 2 2 1 UAA transporter family DUF3492 PF11997.8 EGG24782.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) K1 PF02960.14 EGG24782.1 - 0.11 12.6 1.8 0.2 11.8 0.4 2.1 2 0 0 2 2 2 0 K1 glycoprotein EamA PF00892.20 EGG24782.1 - 0.21 11.7 28.2 0.7 10.1 9.9 3.5 2 2 0 2 2 2 0 EamA-like transporter family EIIC-GAT PF03611.14 EGG24782.1 - 0.24 10.5 16.2 0.71 8.9 0.0 3.3 2 1 1 3 3 3 0 PTS system sugar-specific permease component MARVEL PF01284.23 EGG24782.1 - 0.87 9.6 8.6 14 5.7 6.8 3.0 2 1 0 2 2 2 0 Membrane-associating domain Sec63 PF02889.16 EGG24784.1 - 1.6e-80 270.0 5.7 3.2e-58 196.9 0.4 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGG24784.1 - 4.6e-14 52.6 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGG24784.1 - 3.3e-07 30.5 0.2 1e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EGG24784.1 - 0.03 13.8 0.0 0.081 12.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 EGG24784.1 - 0.032 13.3 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Helicase_PWI PF18149.1 EGG24785.1 - 7.7e-06 26.1 0.9 2.1e-05 24.6 0.3 2.1 1 1 0 1 1 1 1 N-terminal helicase PWI domain Robl_LC7 PF03259.17 EGG24786.1 - 1.8e-08 34.0 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EGG24786.1 - 0.087 12.8 0.0 0.093 12.7 0.0 1.1 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 UBX PF00789.20 EGG24787.1 - 3.1e-13 49.7 0.6 1.6e-05 25.0 0.1 2.7 2 0 0 2 2 2 2 UBX domain TUG-UBL1 PF11470.8 EGG24787.1 - 0.00019 21.6 0.0 0.00093 19.4 0.0 2.3 1 0 0 1 1 1 1 TUG ubiquitin-like domain Ntox4 PF15541.6 EGG24787.1 - 0.084 13.2 0.1 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial toxin 4 DUF4777 PF16007.5 EGG24787.1 - 0.14 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) CpxA_peri PF16527.5 EGG24787.1 - 0.88 10.0 7.2 0.45 10.9 2.0 2.6 2 0 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain PAP1 PF08601.10 EGG24787.1 - 1.3 8.6 45.7 0.46 10.2 25.9 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 SPX PF03105.19 EGG24787.1 - 1.6 8.6 38.1 0.13 12.1 20.3 2.3 2 0 0 2 2 2 0 SPX domain E1-E2_ATPase PF00122.20 EGG24788.1 - 2.8e-42 144.3 2.4 6.4e-42 143.1 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGG24788.1 - 3.6e-34 118.9 0.2 6.8e-34 118.0 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGG24788.1 - 7.2e-12 45.6 0.9 1.2e-08 35.3 0.1 2.8 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EGG24788.1 - 3.1e-06 27.1 10.1 0.013 15.3 0.2 4.0 4 0 0 4 4 4 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGG24788.1 - 0.18 12.2 0.0 0.47 10.8 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3671 PF12420.8 EGG24788.1 - 2.5 8.2 5.0 13 5.9 1.4 3.0 2 0 0 2 2 2 0 Protein of unknown function DUF2615 PF11027.8 EGG24789.1 - 0.048 13.8 0.3 0.048 13.8 0.3 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) EGF_alliinase PF04863.13 EGG24789.1 - 3 8.3 6.7 0.6 10.5 2.7 2.0 2 1 0 2 2 2 0 Alliinase EGF-like domain CDP-OH_P_transf PF01066.21 EGG24790.1 - 1.5e-14 54.5 0.2 1.5e-14 54.5 0.2 3.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Mntp PF02659.15 EGG24790.1 - 0.0092 15.7 1.0 0.041 13.6 0.2 2.2 2 0 0 2 2 2 1 Putative manganese efflux pump CPSase_L_D2 PF02786.17 EGG24791.1 - 3.7e-76 255.3 0.1 3.7e-76 255.3 0.1 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGG24791.1 - 3.9e-45 152.9 0.1 9.5e-45 151.7 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGG24791.1 - 1e-38 131.7 0.0 3.3e-38 130.1 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGG24791.1 - 3.4e-16 58.8 0.3 7.1e-16 57.8 0.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 EGG24791.1 - 2.1e-12 47.5 0.2 1.2e-11 45.1 0.0 2.2 2 0 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 EGG24791.1 - 5.1e-10 39.2 0.1 2.8e-09 36.8 0.1 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGG24791.1 - 1.5e-07 31.1 0.1 4.4e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGG24791.1 - 8e-07 29.2 0.3 2.1e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EGG24791.1 - 0.0014 18.0 0.0 0.014 14.6 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Biotin_lipoyl_2 PF13533.6 EGG24791.1 - 0.0035 17.2 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_5 PF13549.6 EGG24791.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain BsuPI PF12690.7 EGG24791.1 - 0.08 13.0 0.1 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 Intracellular proteinase inhibitor RnfC_N PF13375.6 EGG24791.1 - 0.24 11.4 1.4 0.81 9.7 0.1 2.3 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain ThiF PF00899.21 EGG24792.1 - 1.9e-46 158.4 0.1 2.6e-46 158.0 0.1 1.1 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 EGG24792.1 - 0.0031 17.1 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EGG24792.1 - 0.0078 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EGG24792.1 - 0.069 13.4 0.0 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain ECSIT PF06239.11 EGG24792.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway FAD_binding_3 PF01494.19 EGG24792.1 - 0.14 11.4 0.2 0.22 10.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain FH2 PF02181.23 EGG24793.1 - 1.2e-82 278.0 11.5 1.2e-82 278.0 11.5 3.0 3 0 0 3 3 3 1 Formin Homology 2 Domain FHA PF00498.26 EGG24793.1 - 3.1e-05 24.3 1.6 0.09 13.1 0.1 3.9 3 0 0 3 3 3 2 FHA domain zf-C3HC4_3 PF13920.6 EGG24794.1 - 7.2e-09 35.4 12.7 1e-08 34.9 12.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGG24794.1 - 9.8e-08 31.7 15.7 1.6e-07 31.0 15.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG24794.1 - 1.1e-07 32.0 16.5 1.8e-07 31.4 16.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGG24794.1 - 2.1e-06 27.5 16.9 3.6e-06 26.7 16.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGG24794.1 - 2.1e-05 24.4 6.6 2.1e-05 24.4 6.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGG24794.1 - 2.3e-05 24.6 12.6 4.5e-05 23.7 12.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGG24794.1 - 6.3e-05 22.8 14.1 0.00044 20.0 14.8 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGG24794.1 - 0.00052 19.9 15.7 0.0016 18.3 15.8 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 EGG24794.1 - 0.034 14.0 6.3 0.12 12.2 6.4 1.8 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EGG24794.1 - 0.04 14.1 13.9 0.17 12.1 13.8 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Zn-C2H2_12 PF18112.1 EGG24794.1 - 0.076 13.5 4.2 0.53 10.8 0.3 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-ANAPC11 PF12861.7 EGG24794.1 - 0.086 12.9 7.2 0.21 11.7 7.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EGG24794.1 - 2.3 8.1 14.5 8 6.3 9.8 2.8 2 1 0 2 2 2 0 RING-like zinc finger RecR PF02132.15 EGG24794.1 - 2.4 7.8 7.2 1 9.0 2.5 2.4 2 0 0 2 2 2 0 RecR protein Rad50_zn_hook PF04423.14 EGG24794.1 - 2.7 7.9 8.4 2.2 8.2 0.1 3.1 3 1 0 3 3 3 0 Rad50 zinc hook motif Glyco_transf_20 PF00982.21 EGG24795.1 - 2.1e-151 504.8 0.0 3.1e-151 504.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGG24795.1 - 3.2e-09 36.3 0.0 6.5e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 EGG24795.1 - 0.073 12.8 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain eIF-5a PF01287.20 EGG24796.1 - 3.1e-27 94.5 0.2 4.4e-27 94.0 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EGG24796.1 - 0.00039 20.4 0.1 0.00055 19.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain OCD_Mu_crystall PF02423.15 EGG24797.1 - 2.1e-64 217.5 0.2 2.6e-64 217.2 0.2 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EGG24797.1 - 1.1e-06 28.7 0.2 1.7e-06 28.1 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EGG24797.1 - 0.022 15.4 0.1 0.074 13.6 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 EGG24797.1 - 0.025 13.9 0.1 0.048 13.0 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 EGG24797.1 - 0.083 13.3 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain zf-RING_2 PF13639.6 EGG24798.1 - 0.00063 20.0 4.9 0.0016 18.7 4.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3H2C3 PF17122.5 EGG24798.1 - 0.0062 16.5 3.0 0.0062 16.5 3.0 2.0 2 0 0 2 2 2 1 Zinc-finger Prok-RING_1 PF14446.6 EGG24798.1 - 0.013 15.4 0.8 0.034 14.1 0.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 EGG24798.1 - 0.014 15.3 3.0 0.032 14.2 3.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 EGG24798.1 - 0.016 15.0 0.4 0.016 15.0 0.4 1.9 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 EGG24798.1 - 0.073 13.1 7.0 0.18 11.9 7.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 EGG24798.1 - 0.076 13.3 5.6 0.28 11.5 5.6 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGG24798.1 - 0.12 12.3 1.2 0.37 10.7 1.2 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3915 PF13054.6 EGG24798.1 - 0.24 11.4 4.9 0.079 12.9 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) zf-C3HC4_2 PF13923.6 EGG24798.1 - 0.3 11.0 8.1 0.19 11.6 3.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG24798.1 - 9.2 6.2 6.6 1.1e+02 2.8 6.9 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ELO PF01151.18 EGG24799.1 - 9.4e-66 221.9 20.7 1.1e-65 221.7 20.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2231 PF09990.9 EGG24799.1 - 0.012 16.1 3.6 2.1 8.8 0.3 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Endonuclease_5 PF04493.14 EGG24800.1 - 4.5e-69 232.1 0.0 5.9e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 EGG24800.1 - 0.0015 18.0 0.0 0.0035 16.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function DUF99 SSP160 PF06933.11 EGG24800.1 - 4.7 5.3 9.9 1.2 7.3 1.9 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Glyoxalase PF00903.25 EGG24801.1 - 3.1e-09 37.1 0.1 8e-07 29.3 0.1 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF155 PF02582.14 EGG24802.1 - 1.1e-38 133.1 0.0 2.3e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cbl_N2 PF02761.14 EGG24803.1 - 6.3e-16 58.9 0.7 2.2e-15 57.1 0.7 1.9 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain zf-C3HC4_3 PF13920.6 EGG24803.1 - 6.6e-14 51.5 11.4 1e-13 50.9 11.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SH2 PF00017.24 EGG24803.1 - 7.7e-08 32.3 0.0 2.6e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 SH2 domain Prok-RING_4 PF14447.6 EGG24803.1 - 0.00065 19.5 12.1 0.0013 18.6 12.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Cbl_N3 PF02762.14 EGG24803.1 - 0.0033 17.2 0.0 0.008 16.0 0.0 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain SPX PF03105.19 EGG24803.1 - 0.0078 16.2 21.2 0.084 12.8 0.2 2.4 2 1 0 2 2 2 2 SPX domain zf-RING_5 PF14634.6 EGG24803.1 - 0.036 14.0 12.4 0.062 13.3 12.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EGG24803.1 - 0.073 13.4 12.6 0.13 12.6 12.6 1.4 1 0 0 1 1 1 0 Ring finger domain Coilin_N PF15862.5 EGG24803.1 - 0.37 10.6 9.1 1.2 9.0 9.1 1.9 1 0 0 1 1 1 0 Coilin N-terminus zf-C3HC4_2 PF13923.6 EGG24803.1 - 1.2 9.1 12.8 2.2 8.2 12.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGG24803.1 - 2 8.6 10.8 13 6.1 11.0 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF3807 PF12720.7 EGG24803.1 - 7.8 6.7 10.0 19 5.5 10.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF3439 PF11921.8 EGG24804.1 - 2.1 8.3 14.1 6.9 6.7 1.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Ank_2 PF12796.7 EGG24806.1 - 0.0033 18.0 0.6 23 5.7 0.0 4.9 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24806.1 - 0.0036 17.8 2.3 22 5.8 0.1 5.3 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24806.1 - 0.03 14.9 2.2 59 4.7 0.0 5.3 4 0 0 4 4 4 0 Ankyrin repeat Adhesin_Dr PF04619.12 EGG24807.1 - 0.086 12.8 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Dr-family adhesin Peptidase_C1 PF00112.23 EGG24808.1 - 1e-60 205.6 1.9 1.4e-60 205.1 1.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGG24808.1 - 0.023 13.5 0.3 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Cluap1 PF10234.9 EGG24809.1 - 0.0037 16.7 5.7 0.0037 16.7 5.7 4.2 3 1 1 4 4 4 1 Clusterin-associated protein-1 UPF0242 PF06785.11 EGG24809.1 - 0.0062 16.7 2.9 0.0062 16.7 2.9 4.4 4 0 0 4 4 4 3 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 EGG24809.1 - 0.0077 16.4 9.4 0.0077 16.4 9.4 5.7 4 2 2 6 6 6 1 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 EGG24809.1 - 0.0095 16.0 15.2 0.0095 16.0 15.2 5.0 3 1 1 4 4 3 1 BRE1 E3 ubiquitin ligase EF-hand_6 PF13405.6 EGG24809.1 - 0.012 15.5 4.0 0.075 13.0 0.0 4.0 4 0 0 4 4 4 0 EF-hand domain APG6_N PF17675.1 EGG24809.1 - 0.014 16.0 8.1 0.014 16.0 8.1 4.6 2 1 2 4 4 4 0 Apg6 coiled-coil region ADIP PF11559.8 EGG24809.1 - 0.015 15.4 7.2 0.015 15.4 7.2 4.8 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding EF-hand_8 PF13833.6 EGG24809.1 - 0.078 12.8 4.3 17 5.3 0.0 4.7 3 1 1 4 4 4 0 EF-hand domain pair EF-hand_1 PF00036.32 EGG24809.1 - 0.12 12.0 0.0 0.12 12.0 0.0 5.0 5 0 0 5 5 4 0 EF hand EF-hand_5 PF13202.6 EGG24809.1 - 0.34 10.5 0.0 0.34 10.5 0.0 2.8 3 0 0 3 3 2 0 EF hand EF-hand_7 PF13499.6 EGG24809.1 - 1.5 9.3 11.7 0.46 11.0 0.1 4.4 4 1 0 4 4 4 0 EF-hand domain pair DUF641 PF04859.12 EGG24809.1 - 2.2 8.6 37.6 0.07 13.5 3.7 4.5 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) RF-1 PF00472.20 EGG24810.1 - 3.3e-18 65.7 0.2 5.6e-18 65.0 0.2 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 EGG24810.1 - 0.036 14.5 0.5 0.051 14.0 0.5 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein VHP PF02209.19 EGG24811.1 - 1.3e-12 47.6 5.2 4.2e-12 45.9 5.2 2.0 1 0 0 1 1 1 1 Villin headpiece domain LRR_4 PF12799.7 EGG24811.1 - 6e-11 42.4 72.8 0.0058 17.0 0.8 10.7 2 2 9 13 13 13 11 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGG24811.1 - 8.4e-07 28.6 45.1 0.18 11.9 0.0 12.1 12 1 1 13 13 13 6 Leucine Rich repeat Peptidase_S10 PF00450.22 EGG24811.1 - 0.012 15.0 2.3 0.026 14.0 2.3 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase CLU PF13236.6 EGG24812.1 - 1.1e-55 188.9 0.0 3e-55 187.5 0.0 1.8 1 0 0 1 1 1 1 Clustered mitochondria TPR_17 PF13431.6 EGG24812.1 - 1.7e-05 24.9 0.8 0.045 14.1 0.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat eIF3_p135 PF12807.7 EGG24812.1 - 8.5e-05 22.7 1.2 8.5e-05 22.7 1.2 3.9 3 1 0 4 4 4 1 Translation initiation factor eIF3 subunit 135 TPR_11 PF13414.6 EGG24812.1 - 0.00048 19.7 0.7 0.0035 17.0 1.3 2.1 2 0 0 2 2 2 1 TPR repeat TOM20_plant PF06552.12 EGG24812.1 - 0.00077 19.3 1.4 0.038 13.7 0.7 3.6 3 1 1 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 DNA_pol_phi PF04931.13 EGG24812.1 - 1.7 6.7 15.3 3.1 5.8 15.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi PI3K_1B_p101 PF10486.9 EGG24812.1 - 5.4 4.7 18.3 0.18 9.5 12.2 1.5 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Utp14 PF04615.13 EGG24812.1 - 8.9 4.7 18.0 17 3.8 18.0 1.4 1 0 0 1 1 1 0 Utp14 protein dCMP_cyt_deam_1 PF00383.23 EGG24813.1 - 9.7e-18 63.9 0.1 2.3e-17 62.7 0.2 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGG24813.1 - 2.6e-12 46.7 0.1 3.8e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EGG24813.1 - 0.037 14.1 1.5 1.6 8.8 0.1 2.2 1 1 1 2 2 2 0 Bd3614-like deaminase SNAD4 PF18750.1 EGG24813.1 - 0.039 14.1 0.1 0.065 13.4 0.1 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Auto_anti-p27 PF06677.12 EGG24813.1 - 0.048 13.8 1.1 0.15 12.2 1.1 1.9 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-FPG_IleRS PF06827.14 EGG24813.1 - 0.1 12.5 3.6 2.1 8.3 3.6 2.8 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS DUF2321 PF10083.9 EGG24813.1 - 0.25 11.0 3.0 0.097 12.3 0.5 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) 7tm_3 PF00003.22 EGG24814.1 - 3.3e-42 144.9 25.0 6.4e-42 143.9 25.0 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 EGG24814.1 - 4.6e-26 91.5 0.3 6.5e-26 91.0 0.3 1.2 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Cullin PF00888.22 EGG24815.1 - 1.3e-25 90.2 12.0 1.3e-25 90.2 12.0 1.8 1 1 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 EGG24815.1 - 1.6e-20 73.4 4.2 1.7e-20 73.3 0.9 2.9 3 1 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 UPF0149 PF03695.13 EGG24815.1 - 0.085 13.1 1.7 0.14 12.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) Pox_F15 PF04596.12 EGG24816.1 - 0.05 13.4 0.0 0.08 12.7 0.0 1.4 1 1 0 1 1 1 0 Poxvirus protein F15 Kinesin PF00225.23 EGG24817.1 - 8e-75 251.8 8.5 9e-40 136.6 0.0 3.1 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 EGG24817.1 - 6.2e-30 104.1 0.0 6.2e-30 104.1 0.0 3.1 2 0 0 2 2 2 1 Microtubule binding CCDC144C PF14915.6 EGG24817.1 - 0.00067 18.9 30.9 0.00067 18.9 30.9 4.4 4 0 0 4 4 4 2 CCDC144C protein coiled-coil region WXG100 PF06013.12 EGG24817.1 - 1.4 9.2 14.4 14 6.0 0.0 6.0 6 0 0 6 6 6 0 Proteins of 100 residues with WXG Lectin_C PF00059.21 EGG24818.1 - 0.013 16.3 0.1 0.014 16.1 0.1 1.1 1 0 0 1 1 1 0 Lectin C-type domain EGF_2 PF07974.13 EGG24819.1 - 0.0014 18.9 7.7 0.0032 17.8 7.7 1.6 1 0 0 1 1 1 1 EGF-like domain TIG PF01833.24 EGG24819.1 - 0.0085 16.1 0.8 0.0085 16.1 0.8 2.9 2 1 0 2 2 2 1 IPT/TIG domain MLD PF11647.8 EGG24819.1 - 0.18 12.1 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 Membrane Localization Domain TPP_enzyme_N PF02776.18 EGG24820.1 - 3.2e-49 166.9 0.1 1.5e-48 164.7 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGG24820.1 - 5e-25 88.1 0.0 8.9e-24 84.0 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGG24820.1 - 2.1e-17 63.1 0.2 2.8e-16 59.5 0.0 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Gasdermin PF04598.12 EGG24820.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Gasdermin pore forming domain TPR_1 PF00515.28 EGG24822.1 - 2.8e-17 61.7 2.3 2.6e-05 23.8 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGG24822.1 - 6.1e-14 50.9 0.2 0.0015 18.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGG24822.1 - 4.6e-09 35.8 2.1 0.017 15.3 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGG24822.1 - 5.3e-07 29.8 2.0 0.00079 19.7 0.2 3.1 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG24822.1 - 1.9e-05 24.3 1.7 0.37 10.9 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG24822.1 - 5.4e-05 22.8 4.9 0.11 12.2 0.3 3.0 3 0 0 3 3 3 2 TPR repeat TPR_15 PF13429.6 EGG24822.1 - 0.0011 18.2 0.1 0.027 13.7 0.2 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGG24822.1 - 0.0013 19.3 1.7 0.28 11.9 0.4 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 EGG24822.1 - 0.0019 18.2 3.6 0.075 13.1 0.0 3.2 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain SNAP PF14938.6 EGG24822.1 - 0.01 15.3 0.7 0.36 10.2 0.1 2.1 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 EGG24822.1 - 0.013 16.0 2.1 1.6 9.3 0.8 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 EGG24822.1 - 0.018 15.1 0.1 0.092 12.8 0.1 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_9 PF13371.6 EGG24822.1 - 0.021 15.0 0.3 0.05 13.8 0.3 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGG24822.1 - 0.025 15.4 0.2 11 7.1 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 EGG24822.1 - 0.032 13.9 1.7 1.5 8.5 0.0 2.8 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 EGG24822.1 - 0.038 13.9 0.7 2.1 8.4 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4363 PF14276.6 EGG24822.1 - 0.04 14.0 2.0 0.29 11.3 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) DNA_pol_B_2 PF03175.13 EGG24822.1 - 0.041 12.7 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral TPR_21 PF09976.9 EGG24822.1 - 0.072 12.8 0.2 5.9 6.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 EGG24822.1 - 0.11 13.2 3.4 4.4 8.2 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Ndc1_Nup PF09531.10 EGG24823.1 - 3.3e-13 49.2 30.0 3.3e-13 49.2 30.0 3.1 1 1 2 3 3 3 2 Nucleoporin protein Ndc1-Nup PTS_EIIA_2 PF00359.22 EGG24823.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 CENP-Q PF13094.6 EGG24825.1 - 0.029 14.6 4.7 0.066 13.4 4.7 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SelP_N PF04592.14 EGG24825.1 - 1.3 8.3 11.1 2.1 7.7 11.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Beta_helix PF13229.6 EGG24826.1 - 5.2e-15 55.6 56.3 2e-09 37.5 28.6 4.2 2 1 3 5 5 5 3 Right handed beta helix region NosD PF05048.13 EGG24826.1 - 1.8e-08 34.0 10.8 1.8e-08 34.0 10.8 3.8 2 1 2 4 4 4 2 Periplasmic copper-binding protein (NosD) Lon_C PF05362.13 EGG24828.1 - 3.4e-70 235.7 0.0 6.5e-70 234.8 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EGG24828.1 - 7.5e-24 84.7 0.1 3.9e-23 82.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 EGG24828.1 - 7.8e-10 39.0 7.2 9.5e-10 38.7 0.3 2.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_2 PF07724.14 EGG24828.1 - 6e-09 36.3 0.1 3.2e-08 33.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGG24828.1 - 9.1e-07 29.0 0.0 2.8e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EGG24828.1 - 2.3e-06 27.5 0.0 4.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase RuvB_N PF05496.12 EGG24828.1 - 4.4e-06 26.5 0.0 2.5e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGG24828.1 - 2.7e-05 24.4 0.1 0.002 18.4 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGG24828.1 - 3.9e-05 24.1 0.9 0.001 19.5 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_PrkA PF08298.11 EGG24828.1 - 0.00048 19.2 0.0 0.001 18.1 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain MCM PF00493.23 EGG24828.1 - 0.00085 18.5 0.0 0.002 17.3 0.0 1.6 1 0 0 1 1 1 1 MCM P-loop domain TIP49 PF06068.13 EGG24828.1 - 0.0073 15.6 0.2 0.0073 15.6 0.2 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_14 PF13173.6 EGG24828.1 - 0.0086 16.1 0.0 0.047 13.7 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG24828.1 - 0.01 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGG24828.1 - 0.011 15.2 0.9 0.028 13.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_3 PF07726.11 EGG24828.1 - 0.013 15.3 0.0 0.047 13.5 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGG24828.1 - 0.017 15.5 0.0 0.068 13.6 0.0 2.2 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EGG24828.1 - 0.025 14.0 0.2 0.088 12.2 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGG24828.1 - 0.077 13.5 0.1 0.077 13.5 0.1 2.4 3 0 0 3 3 2 0 AAA domain Sacchrp_dh_NADP PF03435.18 EGG24828.1 - 0.091 13.0 0.3 0.37 11.1 0.2 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain SKI PF01202.22 EGG24828.1 - 0.095 12.8 1.5 0.58 10.3 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase IstB_IS21 PF01695.17 EGG24828.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 EGG24828.1 - 0.11 12.4 2.1 1.5 8.7 0.1 3.2 2 1 1 3 3 3 0 NTPase AAA_19 PF13245.6 EGG24828.1 - 0.11 12.9 0.1 0.51 10.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 EGG24828.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Lactamase_B_2 PF12706.7 EGG24829.1 - 9.2e-10 38.4 0.5 5.2e-08 32.6 0.4 3.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Ndc1_Nup PF09531.10 EGG24829.1 - 3 6.4 8.0 5.1 5.7 8.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dicty_CAD PF05720.12 EGG24831.1 - 4.6e-12 45.8 0.0 1.4e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Cell-cell adhesion domain Kelch_5 PF13854.6 EGG24831.1 - 1.2e-06 28.3 2.2 0.51 10.4 0.3 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 EGG24831.1 - 1.4e-06 27.8 3.1 0.61 9.7 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 EGG24831.1 - 1.5e-06 28.3 0.3 1.2 9.5 0.0 4.5 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EGG24831.1 - 0.005 16.8 3.1 3.6 7.7 0.6 3.2 3 0 0 3 3 3 2 Kelch motif Actin PF00022.19 EGG24833.1 - 4.8e-113 377.8 0.0 2.3e-112 375.6 0.0 1.8 1 1 0 1 1 1 1 Actin DUF3502 PF12010.8 EGG24833.1 - 0.17 12.6 0.0 0.39 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) Methyltransf_8 PF05148.15 EGG24834.1 - 1.3e-74 250.7 0.1 2.5e-74 249.8 0.1 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EGG24834.1 - 1.4e-05 25.7 0.0 5.8e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG24834.1 - 0.0011 19.7 0.2 0.037 14.7 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain WD40 PF00400.32 EGG24834.1 - 0.0018 19.1 13.0 0.11 13.4 0.2 5.5 5 1 0 5 5 5 2 WD domain, G-beta repeat Methyltransf_32 PF13679.6 EGG24834.1 - 0.047 13.7 2.4 0.14 12.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain GST_N PF02798.20 EGG24835.1 - 5.5e-14 52.3 0.0 7.9e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGG24835.1 - 1.2e-13 51.2 0.0 1.8e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGG24835.1 - 4.8e-10 39.6 0.0 6.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TIG PF01833.24 EGG24837.1 - 9.4e-34 115.3 171.6 1.9e-05 24.7 1.2 17.5 16 1 3 19 19 19 14 IPT/TIG domain zf-LITAF-like PF10601.9 EGG24837.1 - 9.1e-21 73.9 9.4 9.1e-21 73.9 9.4 2.2 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain XYPPX PF02162.17 EGG24837.1 - 0.0019 18.0 24.8 0.0019 18.0 24.8 7.7 2 1 5 7 7 7 2 XYPPX repeat (two copies) T2SS-T3SS_pil_N PF13629.6 EGG24837.1 - 0.12 12.1 3.7 0.78 9.5 0.5 3.6 3 0 0 3 3 3 0 Pilus formation protein N terminal region EGF_2 PF07974.13 EGG24837.1 - 0.15 12.5 13.7 0.33 11.4 13.7 1.6 1 0 0 1 1 1 0 EGF-like domain HypA PF01155.19 EGG24837.1 - 1.3 9.0 3.3 2.8 8.0 2.5 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA EGF_Tenascin PF18720.1 EGG24837.1 - 3.1 8.0 10.6 13 5.9 10.6 2.2 1 0 0 1 1 1 0 Tenascin EGF domain DUF3430 PF11912.8 EGG24838.1 - 7.3e-20 71.9 16.8 9e-20 71.6 16.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF4792 PF16040.5 EGG24838.1 - 0.005 16.7 0.8 0.48 10.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4792) DUF3872 PF12988.7 EGG24838.1 - 0.006 16.4 1.1 0.0061 16.4 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function, B. Theta Gene description (DUF3872) DUF4850 PF16142.5 EGG24838.1 - 0.077 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) DUF3446 PF11928.8 EGG24839.1 - 0.073 13.4 12.6 0.25 11.7 6.5 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Ribosomal_L33 PF00471.20 EGG24839.1 - 0.38 11.2 3.0 13 6.3 0.3 2.5 2 0 0 2 2 2 0 Ribosomal protein L33 DUF621 PF04789.15 EGG24840.1 - 0.029 13.5 1.0 0.063 12.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF621) DUF4514 PF14986.6 EGG24841.1 - 0.044 13.8 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Rol_Rep_N PF18106.1 EGG24842.1 - 0.00033 20.9 0.2 1.9 8.9 0.0 3.2 3 0 0 3 3 3 2 Rolling Circle replication initiation protein N-terminal domain DUF2970 PF11174.8 EGG24842.1 - 0.0017 18.2 0.0 0.4 10.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2970) Big_3_3 PF13750.6 EGG24842.1 - 0.0093 15.6 3.0 0.045 13.4 0.5 2.7 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) LRR_8 PF13855.6 EGG24842.1 - 0.043 13.6 1.3 0.3 10.9 0.0 3.2 3 0 0 3 3 3 0 Leucine rich repeat TssO PF17561.2 EGG24843.1 - 0.39 10.8 4.3 0.31 11.1 2.5 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO TIG PF01833.24 EGG24844.1 - 0.011 15.8 1.5 0.011 15.8 1.5 1.9 1 1 0 1 1 1 0 IPT/TIG domain DUF3211 PF11485.8 EGG24844.1 - 0.02 15.1 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) EAF PF09816.9 EGG24844.1 - 0.024 15.1 0.6 1.8 9.1 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription elongation factor MID_MedPIWI PF18296.1 EGG24844.1 - 0.036 13.8 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 MID domain of medPIWI MGC-24 PF05283.11 EGG24844.1 - 3.1 8.3 6.7 0.3 11.5 1.8 2.0 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GCN5L1 PF06320.13 EGG24845.1 - 3.7e-45 152.8 5.0 3.7e-45 152.8 5.0 2.0 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) Androgen_recep PF02166.16 EGG24845.1 - 0.037 12.9 12.0 0.05 12.4 12.0 1.3 1 0 0 1 1 1 0 Androgen receptor DUF948 PF06103.11 EGG24845.1 - 0.1 12.9 4.5 0.6 10.4 0.3 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Tet_JBP PF12851.7 EGG24845.1 - 0.11 11.8 4.7 0.13 11.6 4.5 1.4 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DUF1043 PF06295.12 EGG24845.1 - 2.8 8.0 18.0 0.34 10.9 13.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DivIC PF04977.15 EGG24845.1 - 4.5 7.1 20.8 2.6 7.9 0.8 3.1 3 0 0 3 3 3 0 Septum formation initiator Sec5 PF15469.6 EGG24846.1 - 4.5e-44 150.5 1.3 4.5e-44 150.5 1.3 3.7 4 0 0 4 4 4 1 Exocyst complex component Sec5 RA PF00788.23 EGG24846.1 - 6.7e-06 26.6 0.1 2.8e-05 24.7 0.1 2.1 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Vps51 PF08700.11 EGG24846.1 - 0.00017 21.6 0.4 0.00093 19.2 0.4 2.4 1 0 0 1 1 1 1 Vps51/Vps67 Hemocyanin_N PF03722.14 EGG24846.1 - 1.1 9.8 6.3 1.2 9.6 0.1 3.4 3 0 0 3 3 3 0 Hemocyanin, all-alpha domain Ank_4 PF13637.6 EGG24847.1 - 9.9e-36 121.7 5.3 7.7e-14 51.9 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG24847.1 - 1.8e-35 121.4 9.4 1.5e-16 60.7 0.6 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG24847.1 - 3.6e-31 103.7 3.5 3.1e-06 27.1 0.0 6.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EGG24847.1 - 5e-27 93.6 7.3 4.8e-07 29.9 0.2 5.8 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EGG24847.1 - 3.9e-25 87.2 12.0 2.4e-05 24.6 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat DUF2520 PF10728.9 EGG24847.1 - 0.0073 16.1 3.7 0.15 11.8 0.2 2.9 1 1 1 2 2 2 1 Domain of unknown function (DUF2520) Thg1 PF04446.12 EGG24848.1 - 1.8e-25 89.4 0.7 1.8e-25 89.4 0.7 2.4 3 0 0 3 3 3 1 tRNAHis guanylyltransferase Presenilin PF01080.17 EGG24848.1 - 0.76 8.5 5.7 3.2 6.4 0.6 2.0 2 0 0 2 2 2 0 Presenilin Corazonin PF17308.2 EGG24848.1 - 1.3 9.4 21.4 0.4 11.0 14.2 2.4 2 0 0 2 2 2 0 Pro-corazonin FERM_f0 PF16511.5 EGG24849.1 - 4.8e-05 23.6 0.0 6.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM PRC2_HTH_1 PF18118.1 EGG24850.1 - 0.014 16.1 2.4 0.014 16.1 2.4 7.3 4 2 0 5 5 5 0 Polycomb repressive complex 2 tri-helical domain dsDNA_bind PF01984.20 EGG24851.1 - 9e-29 100.0 16.3 9.8e-29 99.9 16.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF2397 PF09660.10 EGG24851.1 - 0.038 12.9 7.0 0.042 12.8 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) HTH_Tnp_Mu_1 PF02316.16 EGG24851.1 - 0.17 12.1 2.9 0.22 11.7 2.9 1.3 1 1 0 1 1 1 0 Mu DNA-binding domain DUF4192 PF13830.6 EGG24851.1 - 3.7 7.5 6.2 3.8 7.5 6.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF4380 PF14315.6 EGG24852.1 - 0.00027 20.0 0.1 0.00042 19.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4380) Pkinase_Tyr PF07714.17 EGG24853.1 - 6.5e-36 123.9 0.1 2.7e-17 62.9 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EGG24853.1 - 7.4e-25 87.8 0.3 3.8e-13 49.4 0.0 3.0 2 1 0 3 3 3 2 Protein kinase domain SH2 PF00017.24 EGG24853.1 - 3.2e-11 43.2 0.0 9.9e-11 41.6 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Cbl_N2 PF02761.14 EGG24853.1 - 3.1e-05 24.6 0.2 0.00011 22.9 0.2 1.9 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 PF02762.14 EGG24853.1 - 4.1e-05 23.4 0.1 0.0001 22.1 0.1 1.7 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain IBP39 PF11422.8 EGG24853.1 - 0.02 14.7 0.0 0.063 13.0 0.0 1.9 1 0 0 1 1 1 0 Initiator binding protein 39 kDa GrlR PF16518.5 EGG24853.1 - 0.077 13.0 0.4 1.9 8.5 0.0 2.8 2 1 0 2 2 2 0 T3SS negative regulator,GrlR Neugrin PF06413.11 EGG24854.1 - 4.8e-11 43.1 5.1 4.8e-11 43.1 5.1 3.0 2 2 1 3 3 3 1 Neugrin HTH_7 PF02796.15 EGG24854.1 - 1.4e-05 25.0 0.1 3.4e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase MRP-L20 PF12824.7 EGG24854.1 - 5.5e-05 23.4 6.0 5.5e-05 23.4 6.0 3.6 3 1 1 4 4 4 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.12 EGG24854.1 - 0.017 15.0 0.1 0.049 13.6 0.1 1.7 1 0 0 1 1 1 0 HTH domain Pox_A_type_inc PF04508.12 EGG24854.1 - 0.89 9.5 5.0 4.9 7.2 3.5 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PRP38 PF03371.15 EGG24855.1 - 1.2e-34 119.7 0.1 1.6e-34 119.3 0.1 1.2 1 0 0 1 1 1 1 PRP38 family HABP4_PAI-RBP1 PF04774.15 EGG24857.1 - 8.3e-15 55.7 5.0 8.3e-15 55.7 5.0 3.3 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family RNA_pol_Rpb2_1 PF04563.15 EGG24858.1 - 7.5e-44 149.7 0.3 1.2e-43 149.0 0.3 1.4 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EGG24858.1 - 0.0055 16.4 0.0 0.0089 15.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EGG24859.1 - 1.2e-15 57.5 0.2 2.6e-15 56.5 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EGG24859.1 - 1.5e-09 38.2 4.3 1.1e-08 35.5 4.3 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_6 PF00562.28 EGG24859.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_6 PF00562.28 EGG24860.1 - 3.3e-44 151.5 0.1 4.1e-44 151.2 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 EGG24860.1 - 9.7e-33 112.4 0.2 1.5e-32 111.8 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 FNIP PF05725.12 EGG24861.1 - 6.6e-11 42.2 19.2 0.00032 20.8 0.1 8.3 9 1 2 11 11 10 4 FNIP Repeat LRR_1 PF00560.33 EGG24861.1 - 0.74 10.6 5.6 44 5.2 0.0 5.2 4 0 0 4 4 4 0 Leucine Rich Repeat Peptidase_C1 PF00112.23 EGG24862.1 - 4.5e-56 190.4 0.5 8.4e-56 189.5 0.5 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG24862.1 - 1.7e-10 41.1 1.8 3.1e-10 40.3 1.8 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) AbLIM_anchor PF16182.5 EGG24862.1 - 0.043 13.7 0.1 0.043 13.7 0.1 2.4 3 0 0 3 3 3 0 Putative adherens-junction anchoring region of AbLIM DUF3446 PF11928.8 EGG24862.1 - 0.1 12.9 27.9 1.8 8.9 19.9 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain SUZ PF12752.7 EGG24862.1 - 5.1 7.9 6.0 3.3 8.6 1.1 2.3 2 0 0 2 2 2 0 SUZ domain Coiled PF05710.12 EGG24863.1 - 1.2e-20 74.2 25.5 1.3e-20 74.0 25.5 1.0 1 0 0 1 1 1 1 Coiled coil DNase_II PF03265.15 EGG24865.1 - 1.8e-19 70.2 1.0 3.8e-11 42.9 0.1 2.5 2 0 0 2 2 2 2 Deoxyribonuclease II SUIM_assoc PF16619.5 EGG24865.1 - 0.051 13.6 5.2 0.19 11.8 5.2 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SAP25 PF15476.6 EGG24866.1 - 0.034 13.8 15.2 0.043 13.5 15.2 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 Tmemb_cc2 PF10267.9 EGG24866.1 - 0.14 11.3 6.0 0.14 11.3 6.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF4834 PF16118.5 EGG24866.1 - 0.45 11.5 3.5 0.84 10.6 3.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) SPX PF03105.19 EGG24866.1 - 1.3 8.9 15.0 1.3 8.9 15.0 1.0 1 0 0 1 1 1 0 SPX domain FAM199X PF15814.5 EGG24866.1 - 1.4 7.9 24.1 1.6 7.7 24.1 1.1 1 0 0 1 1 1 0 Protein family FAM199X Apt1 PF10351.9 EGG24866.1 - 2.4 6.9 17.7 2.6 6.8 17.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain HSD3 PF15244.6 EGG24866.1 - 4.1 6.8 17.2 4.5 6.7 17.2 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 BUD22 PF09073.10 EGG24866.1 - 8.2 5.7 10.4 9.1 5.5 10.4 1.1 1 0 0 1 1 1 0 BUD22 SprA-related PF12118.8 EGG24866.1 - 8.6 5.4 19.0 9 5.3 19.0 1.0 1 0 0 1 1 1 0 SprA-related family DUF4614 PF15391.6 EGG24866.1 - 9.2 6.2 25.1 14 5.7 25.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Peptidase_C1 PF00112.23 EGG24867.1 - 3.4e-39 135.2 0.6 4.4e-39 134.8 0.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease SR-25 PF10500.9 EGG24867.1 - 0.3 10.7 10.5 0.41 10.2 10.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 EGG24867.1 - 0.41 9.0 4.9 0.55 8.6 4.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Coiled PF05710.12 EGG24868.1 - 3.6e-20 72.6 25.8 4.1e-20 72.4 25.8 1.0 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 EGG24869.1 - 0.0032 18.3 5.6 0.0039 18.0 5.6 1.2 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 EGG24870.1 - 1.2e-20 74.2 25.5 1.3e-20 74.0 25.5 1.0 1 0 0 1 1 1 1 Coiled coil TPP1 PF10341.9 EGG24871.1 - 0.0028 17.6 0.9 0.0028 17.6 0.9 2.5 2 1 0 2 2 2 1 Shelterin complex subunit, TPP1/ACD DUF3824 PF12868.7 EGG24871.1 - 0.029 15.0 0.8 0.029 15.0 0.8 2.6 3 0 0 3 3 3 0 Domain of unknwon function (DUF3824) GCV_T PF01571.21 EGG24872.1 - 2.1e-06 27.3 1.3 5.2e-05 22.7 1.3 2.2 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain SMC_hinge PF06470.13 EGG24873.1 - 5.5e-24 84.7 0.2 8.1e-23 81.0 0.0 3.1 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 EGG24873.1 - 3.7e-23 82.1 101.1 5e-19 68.6 0.0 4.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGG24873.1 - 1e-12 48.5 17.5 1.1e-06 28.7 0.0 3.3 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGG24873.1 - 1.6e-06 27.8 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EGG24873.1 - 0.0033 18.0 40.4 0.0033 18.0 40.4 9.1 2 2 3 5 5 5 1 AAA domain Phi_1 PF04674.12 EGG24873.1 - 1.4 8.1 4.0 3.8 6.8 4.0 1.7 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region PhoLip_ATPase_C PF16212.5 EGG24874.1 - 4.5e-73 246.1 27.5 4.5e-73 246.1 27.5 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGG24874.1 - 1.1e-23 82.7 1.4 6.2e-23 80.3 1.4 2.3 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGG24874.1 - 4.5e-13 49.1 0.0 9.7e-12 44.8 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGG24874.1 - 3.8e-10 39.6 0.0 3.8e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGG24874.1 - 4.6e-08 33.6 0.0 0.071 13.4 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGG24874.1 - 0.00012 21.9 3.2 0.00059 19.6 3.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ank_4 PF13637.6 EGG24875.1 - 0.00012 22.6 0.5 0.11 13.2 0.0 4.7 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG24875.1 - 0.00068 20.2 0.1 0.78 10.4 0.0 4.3 3 1 2 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG24875.1 - 0.00094 19.5 0.6 14 6.6 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeat SAD_SRA PF02182.17 EGG24875.1 - 0.065 12.9 0.5 0.12 12.1 0.5 1.4 1 0 0 1 1 1 0 SAD/SRA domain Aconitase PF00330.20 EGG24876.1 - 2.2e-180 600.6 0.0 3.5e-180 599.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGG24876.1 - 7.5e-38 129.8 0.0 1.3e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain MafB19-deam PF14437.6 EGG24877.1 - 6.4e-08 32.4 0.1 4.2e-06 26.6 0.0 2.6 2 0 0 2 2 2 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EGG24877.1 - 2e-07 30.8 0.1 1.8e-06 27.7 0.1 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region FlaG PF03646.15 EGG24877.1 - 0.037 14.2 1.1 0.037 14.2 1.1 3.1 3 0 0 3 3 3 0 FlaG protein Bd3614-deam PF14439.6 EGG24877.1 - 0.058 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase FAD_binding_3 PF01494.19 EGG24878.1 - 1.2e-16 60.9 0.0 1.7e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EGG24878.1 - 2e-10 40.1 0.0 1.5e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 EGG24878.1 - 8.4e-09 35.5 0.0 0.0016 18.1 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGG24878.1 - 8.8e-06 25.1 0.4 0.0032 16.7 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGG24878.1 - 1.3e-05 24.4 0.0 0.0037 16.4 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein Thi4 PF01946.17 EGG24878.1 - 1.4e-05 24.5 0.0 4.4e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EGG24878.1 - 2e-05 24.7 0.1 8.6e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGG24878.1 - 2.2e-05 24.9 1.8 9.9e-05 22.8 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGG24878.1 - 0.0045 15.7 0.0 0.0074 15.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EGG24878.1 - 0.01 14.9 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EGG24878.1 - 0.021 14.2 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 EGG24878.1 - 0.035 13.7 0.0 0.52 10.0 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 EGG24878.1 - 0.055 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 EGG24878.1 - 0.056 12.6 0.1 7.4 5.6 0.0 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Myb_DNA-binding PF00249.31 EGG24879.1 - 5e-11 42.6 0.0 9.1e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGG24879.1 - 0.00026 20.8 0.4 0.00052 19.9 0.4 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EGG24879.1 - 0.084 13.1 0.1 0.23 11.7 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain ATG16 PF08614.11 EGG24880.1 - 0.15 12.3 6.7 0.26 11.5 6.7 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 EGG24880.1 - 0.27 11.4 6.6 4.7 7.4 6.3 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LIN52 PF10044.9 EGG24880.1 - 0.46 11.2 2.3 0.89 10.3 0.6 2.2 1 1 0 2 2 2 0 Retinal tissue protein eRF1_1 PF03463.15 EGG24881.1 - 0.0084 16.1 1.6 0.015 15.3 1.6 1.3 1 0 0 1 1 1 1 eRF1 domain 1 SOGA PF11365.8 EGG24881.1 - 0.066 14.3 6.8 0.12 13.5 6.8 1.4 1 0 0 1 1 1 0 Protein SOGA DUF872 PF05915.12 EGG24881.1 - 0.16 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF4094 PF13334.6 EGG24881.1 - 0.75 10.2 3.8 2.6 8.5 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) bZIP_1 PF00170.21 EGG24881.1 - 4.8 7.3 7.4 10 6.3 0.6 2.8 1 1 0 2 2 2 0 bZIP transcription factor GHMP_kinases_N PF00288.26 EGG24882.1 - 5.3e-09 36.2 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGG24882.1 - 0.00035 20.9 0.0 0.00071 19.9 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Lipase_GDSL PF00657.22 EGG24883.1 - 1.1e-08 35.3 0.0 1.9e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SapB_2 PF03489.17 EGG24883.1 - 5.6e-06 26.4 1.7 1.1e-05 25.4 0.5 2.2 2 0 0 2 2 2 1 Saposin-like type B, region 2 Lipase_GDSL_2 PF13472.6 EGG24883.1 - 4.9e-05 23.8 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cu-binding_MopE PF11617.8 EGG24883.1 - 0.017 15.2 1.0 0.067 13.4 1.0 2.0 1 1 0 1 1 1 0 Putative metal-binding motif Rad52_Rad22 PF04098.15 EGG24885.1 - 2.2e-08 34.1 0.0 3.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_1 PF00076.22 EGG24885.1 - 2.1e-07 30.7 0.0 4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 EGG24886.1 - 1.4e-65 217.2 3.1 1.4e-24 85.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.31 EGG24887.1 - 6.5e-08 32.6 0.5 1.2e-07 31.8 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain Urm1 PF09138.11 EGG24888.1 - 5.9e-34 116.3 0.1 6.5e-34 116.2 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EGG24888.1 - 0.0013 19.3 0.0 0.0015 19.1 0.0 1.2 1 0 0 1 1 1 1 ThiS family Ribosomal_L26 PF16906.5 EGG24889.1 - 5e-34 116.6 1.4 6.6e-34 116.2 1.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EGG24889.1 - 2.8e-05 23.9 4.2 2.8e-05 23.9 4.2 1.7 2 0 0 2 2 2 1 KOW motif Methyltrans_RNA PF04452.14 EGG24889.1 - 0.021 14.2 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 RNA methyltransferase DNA_ligase_A_N PF04675.14 EGG24891.1 - 2.8e-39 135.2 0.2 7.2e-39 133.9 0.2 1.8 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 EGG24891.1 - 9e-19 67.7 4.1 9.7e-10 38.7 0.0 3.3 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 EGG24891.1 - 9.9e-18 64.6 0.0 3.4e-17 62.9 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 EGG24891.1 - 8.4e-17 61.3 4.3 2.5e-07 31.0 0.0 3.9 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 EGG24891.1 - 2.7e-13 49.8 1.2 7.4e-13 48.4 1.2 1.8 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 EGG24891.1 - 8.3e-07 29.2 0.2 0.003 17.8 0.1 2.8 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EGG24891.1 - 3.2e-05 23.9 1.1 0.013 15.6 0.3 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain CBM49 PF09478.10 EGG24892.1 - 9.8e-34 115.5 4.1 2.6e-19 69.3 0.3 2.4 2 0 0 2 2 2 2 Carbohydrate binding domain CBM49 SOG2 PF10428.9 EGG24892.1 - 0.87 8.7 45.6 1.6 7.8 45.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein TIG PF01833.24 EGG24893.1 - 0.00037 20.5 0.2 0.00076 19.5 0.2 1.5 1 0 0 1 1 1 1 IPT/TIG domain UAA PF08449.11 EGG24894.1 - 1e-62 212.1 22.1 1.3e-62 211.7 22.1 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGG24894.1 - 1.5e-07 31.6 26.3 0.00059 20.0 14.4 2.6 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 EGG24894.1 - 0.00014 21.3 15.1 0.00029 20.3 15.1 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family Pex24p PF06398.11 EGG24894.1 - 0.22 10.5 2.9 0.11 11.4 0.2 1.8 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Peptidase_M20 PF01546.28 EGG24895.1 - 2e-33 115.8 0.0 2.7e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGG24895.1 - 1.8e-13 50.3 0.0 3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGG24895.1 - 4.2e-06 26.6 0.0 6.1e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 MRP-L20 PF12824.7 EGG24896.1 - 0.0017 18.6 1.2 0.0017 18.6 1.2 2.2 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 ORF6N PF10543.9 EGG24896.1 - 0.035 14.3 2.0 0.069 13.4 1.7 1.9 1 1 0 1 1 1 0 ORF6N domain Vma12 PF11712.8 EGG24896.1 - 0.055 13.5 1.1 0.098 12.7 0.8 1.4 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase HTH_3 PF01381.22 EGG24896.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix Myb_DNA-binding PF00249.31 EGG24897.1 - 5.8e-11 42.4 0.1 2e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGG24897.1 - 4.6e-05 23.6 4.9 0.05 13.9 1.5 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Ank_2 PF12796.7 EGG24898.1 - 1.2e-16 61.0 4.6 3.7e-05 24.2 0.0 6.0 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24898.1 - 4.7e-06 27.0 3.3 0.07 13.7 0.1 6.1 4 3 4 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24898.1 - 1.2e-05 25.3 0.1 74 4.4 0.0 8.9 10 0 0 10 10 10 0 Ankyrin repeat Ank_5 PF13857.6 EGG24898.1 - 0.002 18.4 0.0 33 5.0 0.0 5.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) p450 PF00067.22 EGG24899.1 - 1.4e-89 301.0 0.0 1.6e-89 300.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGG24900.1 - 7.7e-88 295.2 0.0 8.9e-88 295.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cnd1 PF12717.7 EGG24900.1 - 0.029 14.4 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Lectin_C PF00059.21 EGG24901.1 - 0.0043 17.8 2.9 0.0056 17.4 0.3 2.4 2 1 0 2 2 2 1 Lectin C-type domain Dicty_CTDC PF00526.18 EGG24902.1 - 5.6e-06 26.1 36.2 0.00038 20.3 10.9 18.4 18 3 1 19 19 19 6 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGG24902.1 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain p450 PF00067.22 EGG24903.1 - 8.9e-89 298.3 0.1 1e-88 298.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 CECR6_TMEM121 PF14997.6 EGG24903.1 - 0.072 12.9 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 CECR6/TMEM121 family BCS1_N PF08740.11 EGG24904.1 - 6e-21 75.3 0.1 1.3e-20 74.2 0.1 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGG24904.1 - 7.8e-20 71.6 0.0 1.6e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGG24904.1 - 0.0036 17.3 0.0 0.0086 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGG24904.1 - 0.009 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 EGG24904.1 - 0.0091 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EGG24904.1 - 0.011 15.6 1.3 0.048 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGG24904.1 - 0.021 15.2 0.9 0.65 10.4 0.0 3.3 3 1 1 4 4 4 0 RNA helicase AAA_24 PF13479.6 EGG24904.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGG24904.1 - 0.085 13.2 0.2 0.46 10.8 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain FAD_binding_1 PF00667.20 EGG24905.1 - 2.8e-33 115.4 0.2 5.8e-33 114.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EGG24905.1 - 4.2e-14 53.1 0.0 2.4e-13 50.7 0.0 2.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Oxidored-like PF09791.9 EGG24905.1 - 6.7e-12 44.9 3.6 6.7e-12 44.9 3.6 2.0 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal SR-25 PF10500.9 EGG24905.1 - 0.0047 16.6 0.4 0.013 15.1 0.4 1.8 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein NAD_binding_6 PF08030.12 EGG24905.1 - 0.0092 16.1 0.2 0.0092 16.1 0.2 2.4 3 0 0 3 3 3 1 Ferric reductase NAD binding domain Cwf_Cwc_15 PF04889.12 EGG24905.1 - 0.034 13.9 11.8 0.037 13.8 10.0 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein 2H-phosphodiest PF08975.10 EGG24905.1 - 0.065 13.2 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1868) Myc_N PF01056.18 EGG24905.1 - 0.5 10.2 9.7 0.045 13.7 4.9 1.6 2 0 0 2 2 2 0 Myc amino-terminal region SLAIN PF15301.6 EGG24905.1 - 1.8 7.7 12.3 0.12 11.6 7.1 1.6 2 0 0 2 2 2 0 SLAIN motif-containing family Med13_C PF06333.12 EGG24905.1 - 3.5 6.8 11.3 5.3 6.2 4.8 2.3 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain CENP-B_dimeris PF09026.10 EGG24905.1 - 3.7 8.0 15.6 1.3 9.4 12.1 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CH PF00307.31 EGG24906.1 - 3.2e-41 139.9 14.2 8.3e-23 80.7 0.1 4.5 4 0 0 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGG24906.1 - 1.3e-09 37.7 0.4 2e-06 27.6 0.1 3.4 2 0 0 2 2 2 2 CAMSAP CH domain bZIP_1 PF00170.21 EGG24909.1 - 0.0059 16.7 15.2 0.0093 16.0 5.2 2.4 2 0 0 2 2 2 1 bZIP transcription factor PikAIV_N PF18605.1 EGG24909.1 - 0.03 13.9 0.4 0.067 12.8 0.4 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DivIC PF04977.15 EGG24909.1 - 0.034 13.9 10.8 0.12 12.1 2.7 2.3 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 EGG24909.1 - 0.038 14.1 6.4 0.12 12.5 1.0 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Syntaxin-6_N PF09177.11 EGG24909.1 - 0.052 14.1 7.8 0.096 13.3 7.7 1.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TMEM192 PF14802.6 EGG24909.1 - 0.43 9.6 4.1 0.59 9.2 1.4 2.4 1 1 2 3 3 3 0 TMEM192 family DUF4407 PF14362.6 EGG24909.1 - 0.45 9.8 7.5 0.59 9.4 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSCB_C PF07743.13 EGG24909.1 - 0.56 10.7 4.2 2 9.0 0.6 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF3450 PF11932.8 EGG24909.1 - 0.71 9.1 7.0 1 8.6 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ABC_tran_CTD PF16326.5 EGG24909.1 - 0.89 9.8 4.6 3.7 7.9 4.6 1.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain Bap31_Bap29_C PF18035.1 EGG24909.1 - 0.96 9.5 7.9 5.7 7.0 0.3 2.3 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain V_ATPase_I PF01496.19 EGG24909.1 - 1.2 7.0 12.8 1.4 6.8 12.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 EGG24909.1 - 1.9 8.5 17.5 1.8 8.6 6.8 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 EGG24909.1 - 2.3 8.7 10.4 1.2 9.6 1.5 2.3 2 0 0 2 2 2 0 Cell division protein ZapB LMBR1 PF04791.16 EGG24909.1 - 3.9 6.3 5.9 4 6.2 5.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TSC22 PF01166.18 EGG24909.1 - 4.6 7.6 13.7 3.6 8.0 1.3 3.3 2 1 1 3 3 3 0 TSC-22/dip/bun family Sulfotransfer_1 PF00685.27 EGG24910.1 - 8.4e-19 68.1 0.1 5.2e-18 65.5 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Glycos_transf_1 PF00534.20 EGG24910.1 - 6.1e-12 45.4 0.0 2.7e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGG24910.1 - 8.5e-12 45.7 0.0 1.7e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sulfotransfer_3 PF13469.6 EGG24910.1 - 7.1e-11 42.9 0.2 1.4e-05 25.6 0.0 2.8 2 1 0 2 2 2 2 Sulfotransferase family Usp PF00582.26 EGG24911.1 - 6.5e-22 78.6 0.0 8.8e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family HyaE PF07449.11 EGG24911.1 - 0.041 13.8 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Cu_amine_oxidN1 PF07833.11 EGG24912.1 - 0.083 13.4 5.7 0.37 11.3 0.1 3.3 3 1 0 3 3 3 0 Copper amine oxidase N-terminal domain FNIP PF05725.12 EGG24913.1 - 0.0041 17.2 27.9 14 6.0 0.0 9.3 10 1 0 11 11 11 5 FNIP Repeat FNIP PF05725.12 EGG24914.1 - 1e-07 32.0 23.7 0.0012 18.9 0.0 8.8 9 1 1 10 10 10 5 FNIP Repeat FNIP PF05725.12 EGG24915.1 - 0.0014 18.8 21.2 0.16 12.1 0.5 7.7 9 0 0 9 9 9 3 FNIP Repeat CwfJ_C_1 PF04677.15 EGG24916.1 - 2.3e-34 117.9 1.3 3.7e-34 117.2 1.3 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EGG24916.1 - 1.1e-23 84.0 0.3 1.1e-23 84.0 0.3 3.3 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 Myosin_head PF00063.21 EGG24917.1 - 4e-261 868.1 7.5 6.7e-261 867.3 7.5 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 EGG24917.1 - 7.9e-49 164.7 1.6 2.4e-25 89.1 0.1 2.9 2 0 0 2 2 2 2 MyTH4 domain IQ PF00612.27 EGG24917.1 - 5.9e-14 50.5 13.8 0.0012 18.4 0.8 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif FERM_M PF00373.18 EGG24917.1 - 5.4e-13 49.4 0.3 1.4e-07 31.9 0.0 3.7 2 1 1 3 3 3 2 FERM central domain SH3_2 PF07653.17 EGG24917.1 - 1.5e-08 34.2 0.0 2.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain RA PF00788.23 EGG24917.1 - 1.6e-08 35.0 0.0 7e-05 23.4 0.0 3.4 3 0 0 3 3 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 EGG24917.1 - 8.8e-08 31.6 0.4 2.2e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGG24917.1 - 1.7e-07 31.0 0.3 6.4e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain FERM_C PF09380.10 EGG24917.1 - 9.9e-06 25.9 5.5 0.0005 20.4 0.2 3.2 3 0 0 3 3 2 2 FERM C-terminal PH-like domain AAA_22 PF13401.6 EGG24917.1 - 0.013 15.7 0.2 0.26 11.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain FERM_N PF09379.10 EGG24917.1 - 0.03 14.3 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 FERM N-terminal domain AAA_16 PF13191.6 EGG24917.1 - 0.099 13.0 0.0 0.099 13.0 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain LicD PF04991.13 EGG24917.1 - 7.5 6.6 14.0 0.65 10.1 2.5 2.9 2 0 0 2 2 2 0 LicD family EGF_2 PF07974.13 EGG24918.1 - 0.0018 18.6 30.5 0.021 15.2 8.5 2.7 2 0 0 2 2 2 2 EGF-like domain DUF3844 PF12955.7 EGG24918.1 - 0.15 12.2 13.6 1.9 8.6 2.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) IDH PF03971.14 EGG24920.1 - 0.039 12.4 0.0 0.071 11.5 0.0 1.4 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase Aminotran_1_2 PF00155.21 EGG24921.1 - 4.7e-55 187.2 0.0 7.1e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Pox_A32 PF04665.12 EGG24921.1 - 0.00053 19.5 0.2 0.0013 18.2 0.1 1.7 2 0 0 2 2 2 1 Poxvirus A32 protein Beta_elim_lyase PF01212.21 EGG24921.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase BppL_N PF18338.1 EGG24922.1 - 0.0015 18.2 0.2 0.004 16.9 0.2 1.7 1 0 0 1 1 1 1 Lower baseplate protein N-terminal domain IF-2B PF01008.17 EGG24923.1 - 2.5e-79 266.4 0.1 3.7e-79 265.9 0.1 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family TFIIA PF03153.13 EGG24923.1 - 0.86 9.5 39.5 1.3 8.9 39.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 EGG24923.1 - 5.1 6.9 19.2 8.5 6.2 19.2 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term WD40 PF00400.32 EGG24924.1 - 7.3e-25 86.8 8.9 3.8e-07 30.7 0.2 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG24924.1 - 1.2e-07 31.9 0.0 0.0023 18.2 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RUN PF02759.19 EGG24925.1 - 7.4e-22 77.8 0.5 9.8e-21 74.1 0.0 3.2 4 0 0 4 4 4 1 RUN domain PH PF00169.29 EGG24925.1 - 2e-06 28.3 0.3 0.00032 21.2 0.1 3.2 2 0 0 2 2 2 1 PH domain Mad3_BUB1_I PF08311.12 EGG24925.1 - 0.018 15.0 0.1 0.064 13.2 0.1 1.9 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 DnaJ PF00226.31 EGG24927.1 - 9.6e-24 83.3 1.2 9.6e-24 83.3 1.2 3.0 3 1 0 3 3 3 1 DnaJ domain zf-C2H2_jaz PF12171.8 EGG24927.1 - 7.4e-11 42.1 14.6 5.6e-10 39.2 4.7 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGG24927.1 - 6.9e-09 35.8 10.7 2.5e-05 24.5 2.1 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGG24927.1 - 6.3e-05 23.5 6.6 0.12 13.3 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EGG24927.1 - 0.0017 18.6 14.6 0.22 11.9 6.3 3.5 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EGG24927.1 - 0.016 15.7 10.6 0.81 10.3 2.7 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_7 PF15269.6 EGG24927.1 - 0.033 14.2 0.8 0.089 12.9 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger zf-C2H2_6 PF13912.6 EGG24927.1 - 0.12 12.4 6.6 0.12 12.4 1.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 EGG24927.1 - 0.23 11.1 3.8 0.28 10.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 EGG24927.1 - 1.1 9.8 11.9 2.4 8.7 0.8 3.3 2 1 0 2 2 2 0 Zinc-finger double domain Ribosomal_S9 PF00380.19 EGG24928.1 - 6.7e-32 110.6 0.1 6.7e-32 110.6 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S9/S16 PHD PF00628.29 EGG24928.1 - 3.3e-05 23.7 1.4 3.3e-05 23.7 1.4 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EGG24928.1 - 0.00074 19.0 1.6 0.00074 19.0 1.6 1.9 2 0 0 2 2 2 1 PHD-finger Pkinase PF00069.25 EGG24930.1 - 3.7e-72 242.9 0.0 3.7e-72 242.9 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG24930.1 - 3.2e-33 115.1 1.4 3.4e-33 115.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG24930.1 - 0.002 17.5 0.0 0.002 17.5 0.0 2.7 2 1 0 2 2 2 1 Kinase-like MIF4G PF02854.19 EGG24931.1 - 1.8e-21 76.8 46.4 3.6e-12 46.4 10.3 5.0 5 0 0 5 5 5 3 MIF4G domain Upf2 PF04050.14 EGG24931.1 - 3.8e-15 56.8 10.7 3.8e-15 56.8 10.7 7.8 3 3 2 5 5 5 1 Up-frameshift suppressor 2 Ank_4 PF13637.6 EGG24932.1 - 0.00022 21.7 0.3 5.8 7.6 0.0 5.8 6 1 0 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24932.1 - 0.0024 18.2 1.0 39 5.3 0.0 6.5 8 0 0 8 8 8 0 Ankyrin repeat Ank_2 PF12796.7 EGG24932.1 - 0.019 15.6 2.1 2.8 8.6 0.0 5.0 5 1 1 6 6 6 0 Ankyrin repeats (3 copies) DUF4904 PF16247.5 EGG24932.1 - 0.09 12.6 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) DUF4834 PF16118.5 EGG24932.1 - 9.6 7.2 8.5 7.7 7.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Ank_4 PF13637.6 EGG24933.1 - 0.0044 17.6 1.7 61 4.3 0.0 7.1 7 0 0 7 7 7 1 Ankyrin repeats (many copies) Gti1_Pac2 PF09729.9 EGG24933.1 - 1.5 8.9 8.2 11 6.0 1.2 3.5 3 0 0 3 3 3 0 Gti1/Pac2 family RabGAP-TBC PF00566.18 EGG24934.1 - 1.2e-56 191.8 2.4 1.2e-56 191.8 2.4 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain HigB_toxin PF09907.9 EGG24934.1 - 0.04 14.1 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system ProRS-C_1 PF09180.11 EGG24935.1 - 1e-22 80.1 3.3 1e-22 80.1 3.3 2.3 3 0 0 3 3 3 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EGG24935.1 - 1.2e-18 67.8 0.0 2.2e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGG24935.1 - 1.5e-11 44.3 0.0 3.4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Ribosomal_60s PF00428.19 EGG24935.1 - 0.01 16.4 2.7 0.01 16.4 2.7 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein VIT1 PF01988.19 EGG24936.1 - 0.48 10.3 1.5 1.2 8.9 1.5 1.7 1 0 0 1 1 1 0 VIT family Tantalus PF15386.6 EGG24937.1 - 0.0071 16.4 0.9 0.4 10.8 0.0 2.3 2 0 0 2 2 2 2 Drosophila Tantalus-like Peptidase_M28 PF04389.17 EGG24939.1 - 4.8e-34 117.8 0.0 9e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 SLC35F PF06027.12 EGG24939.1 - 5e-08 32.8 19.2 5.6e-07 29.4 14.3 3.1 1 1 1 2 2 2 1 Solute carrier family 35 PA PF02225.22 EGG24939.1 - 4.9e-07 29.7 0.2 1.8e-06 27.9 0.1 2.1 2 0 0 2 2 2 1 PA domain EamA PF00892.20 EGG24939.1 - 7.7e-07 29.4 42.8 0.00035 20.7 14.4 3.0 3 1 0 3 3 3 2 EamA-like transporter family DUF3290 PF11694.8 EGG24939.1 - 0.024 14.6 0.6 10 6.1 0.2 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Peptidase_M20 PF01546.28 EGG24939.1 - 0.044 13.5 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Sec23_trunk PF04811.15 EGG24940.1 - 7.8e-62 209.0 0.0 1.2e-61 208.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGG24940.1 - 1.6e-27 96.1 0.1 3e-27 95.2 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EGG24940.1 - 3.3e-24 84.7 0.1 6.8e-24 83.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EGG24940.1 - 2.1e-12 46.9 6.6 3.9e-12 46.0 6.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGG24940.1 - 5e-09 35.9 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EGG24940.1 - 0.063 12.7 0.2 0.15 11.5 0.2 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain TSC22 PF01166.18 EGG24941.1 - 7.1e-05 23.0 1.7 7.1e-05 23.0 1.7 2.7 3 0 0 3 3 3 1 TSC-22/dip/bun family CASP_C PF08172.12 EGG24941.1 - 0.0013 18.1 3.6 0.0013 18.1 3.6 3.7 3 2 0 3 3 3 1 CASP C terminal Pox_A_type_inc PF04508.12 EGG24941.1 - 0.018 14.9 0.3 0.099 12.5 0.0 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat GAS PF13851.6 EGG24941.1 - 0.071 12.5 25.6 0.042 13.2 9.3 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding THOC7 PF05615.13 EGG24941.1 - 0.14 12.4 13.0 0.12 12.7 2.8 3.1 2 1 1 3 3 3 0 Tho complex subunit 7 HrpB7 PF09486.10 EGG24941.1 - 0.95 9.8 4.0 2.9 8.3 1.5 2.3 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) ERM PF00769.19 EGG24941.1 - 0.99 9.2 18.2 0.025 14.4 11.1 1.9 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Lebercilin PF15619.6 EGG24941.1 - 1.1 8.9 21.8 0.046 13.4 15.2 1.9 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Itfg2 PF15907.5 EGG24942.1 - 4.9e-58 196.7 5.2 6.3e-28 97.8 0.0 4.2 2 2 1 3 3 3 3 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 EGG24942.1 - 7.7e-09 35.6 1.3 0.016 15.3 0.1 3.6 2 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region BBS1 PF14779.6 EGG24942.1 - 0.00011 21.7 0.2 0.12 11.8 0.0 3.2 2 1 0 3 3 3 1 Ciliary BBSome complex subunit 1 FG-GAP PF01839.23 EGG24942.1 - 0.00012 22.1 3.3 0.12 12.5 0.7 2.6 2 0 0 2 2 2 2 FG-GAP repeat PHTB1_N PF14727.6 EGG24942.1 - 0.00014 21.4 3.1 0.0004 19.9 0.0 2.3 1 1 1 2 2 2 1 PTHB1 N-terminus BBS2_C PF14782.6 EGG24942.1 - 0.0061 15.4 2.0 0.15 10.8 0.0 2.9 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, C-terminal VCBS PF13517.6 EGG24942.1 - 0.021 15.4 3.1 0.054 14.1 2.4 4.1 3 1 3 6 6 6 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Secretin_N_2 PF07655.13 EGG24942.1 - 0.053 14.1 12.4 0.16 12.5 12.4 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain PliI PF16743.5 EGG24942.1 - 0.11 12.3 0.4 2.5 7.9 0.1 2.6 3 0 0 3 3 3 0 Periplasmic lysozyme inhibitor of I-type lysozyme PRKCSH PF07915.13 EGG24942.1 - 1.4 10.0 6.7 0.26 12.3 1.0 2.6 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein NOA36 PF06524.12 EGG24942.1 - 2.6 7.3 4.4 5.5 6.2 4.4 1.5 1 0 0 1 1 1 0 NOA36 protein Vps8 PF12816.7 EGG24943.1 - 1.4e-51 174.8 5.2 1.9e-50 171.2 1.2 4.1 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EGG24943.1 - 3.9e-10 39.8 10.1 0.00026 20.9 1.8 4.0 3 0 0 3 3 3 3 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 EGG24943.1 - 5.6e-05 23.1 3.2 0.00012 22.1 3.2 1.5 1 0 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 EGG24943.1 - 0.0038 17.2 4.7 0.0083 16.1 4.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGG24943.1 - 0.072 13.0 3.1 0.18 11.7 3.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGG24943.1 - 0.11 12.8 4.9 0.32 11.3 4.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain WD40 PF00400.32 EGG24943.1 - 0.11 13.4 1.5 3.9 8.5 0.4 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-RING_2 PF13639.6 EGG24943.1 - 0.17 12.3 5.4 0.39 11.1 5.4 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 EGG24943.1 - 1.4 8.8 4.9 3.3 7.7 1.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG24943.1 - 2.4 8.1 4.7 6 6.8 4.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 MMR_HSR1_C PF08438.10 EGG24944.1 - 2.4e-38 131.1 0.2 4.3e-38 130.3 0.2 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EGG24944.1 - 2.5e-22 79.1 0.0 6.1e-22 77.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGG24944.1 - 2.5e-09 36.9 0.7 1.7e-07 30.9 0.1 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGG24944.1 - 0.0027 17.6 0.1 0.25 11.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase YchF-GTPase_C PF06071.13 EGG24944.1 - 0.0065 16.6 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) Dynamin_N PF00350.23 EGG24944.1 - 0.017 15.2 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 0 Dynamin family TGS PF02824.21 EGG24944.1 - 0.027 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 TGS domain MMR_HSR1_Xtn PF16897.5 EGG24944.1 - 0.032 14.3 1.0 0.086 12.9 0.1 2.1 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain PH PF00169.29 EGG24945.1 - 1.3e-14 54.6 0.1 4.2e-14 52.9 0.1 2.0 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.30 EGG24945.1 - 9e-08 32.4 0.0 2.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4139 PF13598.6 EGG24945.1 - 3.2e-06 27.0 0.0 4.3e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) PH_8 PF15409.6 EGG24945.1 - 3.2e-06 27.3 0.4 1.1e-05 25.6 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EGG24945.1 - 5.1e-06 26.9 0.2 0.00018 21.9 0.2 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain SAM_2 PF07647.17 EGG24945.1 - 9.2e-05 22.5 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ORC6 PF05460.13 EGG24945.1 - 0.024 13.9 0.9 0.04 13.2 0.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PH_9 PF15410.6 EGG24945.1 - 0.13 12.6 0.0 0.88 10.0 0.0 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain SR-25 PF10500.9 EGG24945.1 - 0.43 10.2 6.4 0.69 9.5 6.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ADP_ribosyl_GH PF03747.14 EGG24946.1 - 1.7e-48 165.8 0.0 2e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Ras PF00071.22 EGG24947.1 - 7.8e-19 67.8 1.7 4.3e-18 65.4 1.7 1.9 1 1 0 1 1 1 1 Ras family NgoMIV_restric PF09015.10 EGG24947.1 - 0.097 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NgoMIV restriction enzyme Spb1_C PF07780.12 EGG24948.1 - 1e-55 188.7 28.3 1e-55 188.7 28.3 4.2 3 2 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 EGG24948.1 - 5.8e-54 182.9 0.2 1.6e-53 181.4 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EGG24948.1 - 6.3e-32 110.7 22.1 6.3e-32 110.7 22.1 6.4 2 1 3 5 5 5 1 Domain of unknown function (DUF3381) Methyltr_RsmB-F PF01189.17 EGG24948.1 - 0.075 12.7 0.0 0.075 12.7 0.0 2.6 3 0 0 3 3 3 0 16S rRNA methyltransferase RsmB/F Gpi16 PF04113.14 EGG24949.1 - 3.6e-134 448.3 0.4 2.8e-133 445.3 0.4 1.8 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component FDC-SP PF15215.6 EGG24949.1 - 0.071 13.7 1.0 1.7 9.2 0.0 2.7 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide ATG13 PF10033.9 EGG24950.1 - 1.9e-19 70.3 0.8 9e-16 58.3 0.1 2.7 2 0 0 2 2 2 2 Autophagy-related protein 13 TBCA PF02970.16 EGG24951.1 - 4.9e-23 81.3 10.7 4.9e-23 81.3 10.7 1.4 2 0 0 2 2 2 1 Tubulin binding cofactor A Phage_Gp17 PF17549.2 EGG24951.1 - 0.04 13.9 3.6 0.035 14.1 2.6 1.4 1 1 0 1 1 1 0 Gene Product 17 TPR_MLP1_2 PF07926.12 EGG24951.1 - 0.37 10.9 11.7 0.87 9.7 11.7 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein LPD5 PF18799.1 EGG24951.1 - 0.86 10.0 8.2 0.62 10.5 6.7 1.5 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 5 MMtag PF10159.9 EGG24951.1 - 2.4 8.5 7.3 0.24 11.7 2.8 1.7 2 0 0 2 2 2 0 Multiple myeloma tumor-associated Cas_Cas6 PF01881.16 EGG24952.1 - 0.55 10.8 5.5 0.22 12.1 0.8 2.1 2 0 0 2 2 2 0 CRISPR associated protein Cas6 PET117 PF15786.5 EGG24953.1 - 4.3e-09 36.5 0.1 8e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial 7tm_1 PF00001.21 EGG24953.1 - 0.014 14.8 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF5608 PF18356.1 EGG24953.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5608) ETRAMP PF09716.10 EGG24953.1 - 0.17 11.9 0.1 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CLU PF13236.6 EGG24954.1 - 6e-53 179.9 0.0 1.3e-52 178.8 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria TPR_12 PF13424.6 EGG24954.1 - 1.1e-42 144.1 8.9 3.9e-13 49.5 0.0 4.9 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 EGG24954.1 - 2.8e-17 62.0 0.1 0.0017 18.2 0.0 6.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGG24954.1 - 8.2e-13 47.6 18.1 0.0011 18.6 0.3 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGG24954.1 - 1.7e-11 43.3 15.1 0.0058 16.7 0.4 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGG24954.1 - 2.4e-11 42.8 3.6 0.0058 16.6 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat eIF3_p135 PF12807.7 EGG24954.1 - 9.1e-11 42.1 0.0 2.8e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_8 PF13181.6 EGG24954.1 - 8.5e-07 28.7 30.6 0.00096 19.2 1.1 6.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGG24954.1 - 1.3e-05 24.7 0.0 0.011 15.1 0.0 2.3 2 0 0 2 2 2 2 MalT-like TPR region DUF2225 PF09986.9 EGG24954.1 - 0.0026 17.5 2.4 0.0026 17.5 2.4 3.6 2 2 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.6 EGG24954.1 - 0.032 14.6 3.7 16 6.1 0.3 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGG24954.1 - 0.051 14.2 4.5 72 4.3 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGG24954.1 - 1.9 8.6 5.0 3.5 7.8 0.2 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EGG24954.1 - 3.6 7.9 9.9 1.2 9.4 0.7 4.4 5 1 1 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.12 EGG24954.1 - 7.7 6.5 9.6 7.8 6.5 0.4 4.3 5 0 0 5 5 5 0 Mad3/BUB1 homology region 1 Na_trans_assoc PF06512.13 EGG24955.1 - 2 8.7 37.6 3.7 7.8 11.1 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated Mpp10 PF04006.12 EGG24955.1 - 4.5 5.6 59.9 6.7 5.0 59.9 1.2 1 0 0 1 1 1 0 Mpp10 protein DRMBL PF07522.14 EGG24957.1 - 4.4e-27 94.5 1.7 1.9e-26 92.4 0.0 3.0 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EGG24957.1 - 0.015 14.8 0.1 0.036 13.6 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain RMMBL PF07521.12 EGG24957.1 - 0.024 14.5 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain CBM49 PF09478.10 EGG24959.1 - 7.9e-15 54.9 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM_4_9 PF02018.17 EGG24959.1 - 0.054 13.8 0.0 0.4 11.0 0.0 2.1 2 0 0 2 2 2 0 Carbohydrate binding domain Glyco_hydro_25 PF01183.20 EGG24960.1 - 5.7e-12 46.2 0.2 6.5e-12 46.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 DUF1906 PF08924.11 EGG24960.1 - 0.00021 21.5 4.1 0.00036 20.7 4.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1906) DUF4834 PF16118.5 EGG24961.1 - 0.11 13.5 1.4 16 6.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SOG2 PF10428.9 EGG24961.1 - 0.18 11.0 5.5 0.22 10.7 5.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF908 PF06012.12 EGG24961.1 - 1.8 7.9 6.7 2.4 7.5 6.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MGC-24 PF05283.11 EGG24961.1 - 1.9 8.9 9.3 3.6 8.0 9.3 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin F-box-like PF12937.7 EGG24962.1 - 7.1e-08 32.2 0.1 7.1e-08 32.2 0.1 3.7 5 0 0 5 5 5 1 F-box-like F-box PF00646.33 EGG24962.1 - 0.00067 19.5 0.3 0.00067 19.5 0.3 2.9 4 0 0 4 4 4 1 F-box domain NAD_binding_4 PF07993.12 EGG24962.1 - 0.1 11.8 0.5 0.17 11.0 0.5 1.3 1 0 0 1 1 1 0 Male sterility protein Allexi_40kDa PF05549.11 EGG24962.1 - 1.3 8.4 12.1 0.78 9.2 9.3 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Ufm1 PF03671.14 EGG24963.1 - 2.5e-41 139.6 0.1 3.9e-41 139.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein DUF2884 PF11101.8 EGG24964.1 - 0.00073 19.1 1.0 0.0011 18.5 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) Dynein_light PF01221.18 EGG24964.1 - 0.0038 17.5 0.0 0.0075 16.6 0.0 1.5 1 0 0 1 1 1 1 Dynein light chain type 1 PI3_PI4_kinase PF00454.27 EGG24965.1 - 3.6e-37 128.5 9.2 1.3e-36 126.7 2.1 3.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGG24965.1 - 1.3e-33 115.9 0.1 3.1e-33 114.8 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.29 EGG24965.1 - 6.7e-12 45.8 1.4 1.5e-11 44.8 0.3 2.3 2 0 0 2 2 2 1 PH domain PI3K_C2 PF00792.24 EGG24965.1 - 1.4e-05 25.0 0.5 0.035 14.0 0.0 2.9 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 EGG24965.1 - 0.0001 21.8 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) ubiquitin PF00240.23 EGG24965.1 - 0.0031 17.2 0.1 0.019 14.7 0.1 2.4 1 0 0 1 1 1 1 Ubiquitin family PH_3 PF14593.6 EGG24965.1 - 0.0094 16.0 0.0 0.036 14.2 0.0 2.0 1 0 0 1 1 1 1 PH domain SUIM_assoc PF16619.5 EGG24965.1 - 0.15 12.1 23.1 0.12 12.5 3.2 3.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PH_11 PF15413.6 EGG24965.1 - 8.5 6.9 7.0 34 4.9 3.1 3.5 2 1 0 2 2 2 0 Pleckstrin homology domain HSP20 PF00011.21 EGG24966.1 - 6.1e-20 71.3 0.0 7.4e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGG24966.1 - 2.7e-08 33.2 0.0 4.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA SMK-1 PF04802.15 EGG24967.1 - 3.8e-62 209.5 9.5 3.8e-62 209.5 9.5 2.4 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 GATA PF00320.27 EGG24968.1 - 3.5e-15 55.3 8.1 7.3e-15 54.3 8.1 1.6 1 0 0 1 1 1 1 GATA zinc finger zf-RING_9 PF13901.6 EGG24970.1 - 9.4e-49 166.2 20.1 9.4e-49 166.2 20.1 2.1 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon RUN PF02759.19 EGG24970.1 - 1.1e-22 80.4 3.9 1.3e-14 54.3 0.1 3.1 2 0 0 2 2 2 2 RUN domain Prok-RING_1 PF14446.6 EGG24970.1 - 0.017 15.1 6.5 0.063 13.2 6.5 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TMEM171 PF15471.6 EGG24970.1 - 0.39 9.7 2.8 1.1 8.1 2.8 1.8 1 0 0 1 1 1 0 Transmembrane protein family 171 USP8_interact PF08941.10 EGG24970.1 - 4.1 7.2 8.4 0.49 10.2 1.0 2.7 2 1 0 2 2 2 0 USP8 interacting DUF4611 PF15387.6 EGG24973.1 - 0.031 14.5 3.6 0.031 14.5 3.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pho88 PF10032.9 EGG24973.1 - 0.12 11.7 6.4 1 8.6 0.3 2.0 1 1 1 2 2 2 0 Phosphate transport (Pho88) BSP_II PF05432.11 EGG24973.1 - 0.19 11.4 22.6 0.22 11.2 22.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2254 PF10011.9 EGG24973.1 - 0.6 8.9 2.0 0.81 8.4 2.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Hydrolase_3 PF08282.12 EGG24973.1 - 0.7 9.6 9.3 0.84 9.3 9.3 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rxt3 PF08642.10 EGG24973.1 - 0.87 10.4 6.4 2.2 9.1 6.4 1.7 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 WRNPLPNID PF15017.6 EGG24973.1 - 1.1 10.1 18.0 0.088 13.7 4.0 2.4 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DUF4778 PF16008.5 EGG24973.1 - 1.5 8.8 10.4 1.9 8.5 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) MMR1 PF08505.10 EGG24973.1 - 3.2 8.0 13.6 3.4 7.9 13.6 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein BHD_2 PF10404.9 EGG24973.1 - 4 8.5 13.9 0.11 13.4 3.4 2.3 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 Presenilin PF01080.17 EGG24973.1 - 5.7 5.6 12.0 6.2 5.5 12.0 1.0 1 0 0 1 1 1 0 Presenilin EphA2_TM PF14575.6 EGG24973.1 - 8.9 7.3 7.0 0.58 11.1 1.4 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain VWA_2 PF13519.6 EGG24974.1 - 3.8e-08 33.9 1.3 0.037 14.7 0.0 4.9 3 1 1 4 4 4 2 von Willebrand factor type A domain Sec23_trunk PF04811.15 EGG24974.1 - 6.7e-06 25.8 5.2 1.1e-05 25.1 0.1 3.4 2 1 1 3 3 3 1 Sec23/Sec24 trunk domain Spt20 PF12090.8 EGG24974.1 - 1.4e-05 24.8 18.0 1.4e-05 24.8 18.0 2.4 2 0 0 2 2 2 1 Spt20 family DUF2076 PF09849.9 EGG24974.1 - 9.9e-05 22.5 23.1 9.9e-05 22.5 23.1 2.6 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) Sec23_BS PF08033.12 EGG24974.1 - 0.0028 18.4 0.1 0.014 16.1 0.1 2.3 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGG24974.1 - 0.032 14.3 0.0 0.094 12.8 0.0 1.9 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger TrwB_AAD_bind PF10412.9 EGG24974.1 - 0.032 13.1 5.8 0.072 12.0 5.8 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain VWA_CoxE PF05762.14 EGG24974.1 - 0.054 12.9 0.1 12 5.2 0.0 2.3 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein TFIIA PF03153.13 EGG24974.1 - 0.22 11.5 52.5 0.18 11.8 21.1 2.9 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Sec1 PF00995.23 EGG24975.1 - 5.8e-87 293.3 0.3 5.2e-72 243.9 0.0 2.0 1 1 0 2 2 2 2 Sec1 family Paramyxo_P PF01806.17 EGG24975.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region Cation_efflux PF01545.21 EGG24976.1 - 6.8e-50 169.6 9.5 6.8e-50 169.6 9.5 2.8 3 1 0 3 3 3 1 Cation efflux family DUF4746 PF15928.5 EGG24976.1 - 4.3 6.7 10.8 6.6 6.1 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GBP PF02263.19 EGG24977.1 - 5.5e-48 163.5 0.1 5.5e-48 163.5 0.1 2.0 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGG24977.1 - 3.7e-07 29.9 22.2 4.5e-06 26.3 22.2 2.6 1 1 0 1 1 1 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 EGG24977.1 - 0.062 13.4 0.0 0.24 11.5 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4854 PF16146.5 EGG24977.1 - 0.11 12.8 5.0 0.37 11.1 5.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) AAA_14 PF13173.6 EGG24977.1 - 0.11 12.5 1.6 0.54 10.3 0.0 3.0 4 0 0 4 4 4 0 AAA domain SF-assemblin PF06705.11 EGG24977.1 - 0.39 10.0 18.2 1.3 8.3 16.1 2.6 2 0 0 2 2 2 0 SF-assemblin/beta giardin Fzo_mitofusin PF04799.13 EGG24977.1 - 4.3 6.9 14.6 3.4 7.2 6.8 3.2 2 1 1 3 3 3 0 fzo-like conserved region Med27 PF11571.8 EGG24978.1 - 3.8e-22 78.4 0.3 3.8e-22 78.4 0.3 2.3 2 0 0 2 2 2 1 Mediator complex subunit 27 AAA PF00004.29 EGG24979.1 - 1.8e-20 73.7 0.0 3.1e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 EGG24979.1 - 1.4e-13 51.2 0.0 2.9e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.6 EGG24979.1 - 0.00014 22.3 0.0 0.00039 20.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGG24979.1 - 0.00019 21.2 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EGG24979.1 - 0.00098 19.6 0.1 0.0025 18.3 0.1 1.9 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.13 EGG24979.1 - 0.001 18.3 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 EGG24979.1 - 0.0041 16.8 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGG24979.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase TIP49 PF06068.13 EGG24979.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 EGG24979.1 - 0.012 16.0 0.0 0.09 13.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DDRGK PF09756.9 EGG24979.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 DDRGK domain MMR_HSR1 PF01926.23 EGG24979.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EGG24979.1 - 0.074 13.2 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGG24979.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EGG24979.1 - 0.11 12.4 0.0 0.54 10.2 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Alba PF01918.21 EGG24980.1 - 2.3e-12 46.6 0.1 5e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 EGG24980.1 - 5.7e-07 29.6 10.4 6.3e-05 23.0 0.0 4.1 2 1 1 3 3 3 1 Rpp20 subunit of nuclear RNase MRP and P NST1 PF13945.6 EGG24980.1 - 0.017 15.2 5.3 0.033 14.3 5.3 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Spt5_N PF11942.8 EGG24980.1 - 0.082 13.9 2.5 0.082 13.9 2.5 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal WD40 PF00400.32 EGG24981.1 - 8.5e-06 26.4 5.1 1.4e-05 25.7 0.2 3.7 2 1 1 3 3 3 1 WD domain, G-beta repeat Hira PF07569.11 EGG24981.1 - 9.6e-05 22.2 0.2 0.12 12.1 0.0 3.1 3 0 0 3 3 3 2 TUP1-like enhancer of split Coatomer_WDAD PF04053.14 EGG24981.1 - 0.0025 16.9 11.0 0.18 10.8 0.0 4.0 4 1 0 4 4 4 2 Coatomer WD associated region CENP-Q PF13094.6 EGG24981.1 - 0.22 11.7 1.0 0.45 10.7 1.0 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit LRR_6 PF13516.6 EGG24982.1 - 2.1e-07 30.4 23.3 0.00012 21.8 0.1 7.5 8 0 0 8 8 8 4 Leucine Rich repeat Carm_PH PF17888.1 EGG24982.1 - 0.0019 18.5 1.4 0.0087 16.4 1.4 2.2 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_1 PF00560.33 EGG24982.1 - 0.0071 16.7 21.8 6.6 7.7 0.1 9.5 10 0 0 10 10 10 2 Leucine Rich Repeat DUF5506 PF17611.2 EGG24982.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5506) Peptidase_S49_N PF08496.10 EGG24982.1 - 8.7 6.4 17.4 33 4.5 17.4 2.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4337 PF14235.6 EGG24982.1 - 9.2 6.4 11.3 20 5.3 11.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HemN_C PF06969.16 EGG24983.1 - 4.8e-09 36.1 0.4 2.1e-08 34.1 0.1 2.0 2 0 0 2 2 2 1 HemN C-terminal domain Radical_SAM PF04055.21 EGG24983.1 - 0.00068 20.1 0.5 0.0087 16.5 0.4 2.5 1 1 0 1 1 1 1 Radical SAM superfamily DUF1133 PF06576.11 EGG24984.1 - 0.051 13.0 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) YtxH PF12732.7 EGG24984.1 - 0.1 13.1 0.2 6.7 7.3 0.1 2.7 2 1 0 2 2 2 0 YtxH-like protein DUF1722 PF08349.11 EGG24984.1 - 0.13 12.5 0.0 29 5.0 0.0 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1722) Ras PF00071.22 EGG24985.1 - 8.2e-11 41.8 0.0 1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Dioxygenase_C PF00775.21 EGG24985.1 - 0.022 14.2 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Dioxygenase DUF3430 PF11912.8 EGG24986.1 - 0.01 15.9 11.7 0.069 13.2 11.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) Ank_2 PF12796.7 EGG24987.1 - 7.9e-23 80.9 0.3 7.1e-10 39.3 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24987.1 - 3.7e-16 59.3 1.4 0.00033 21.1 0.1 5.6 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG24987.1 - 9.6e-16 57.7 2.9 0.018 15.4 0.1 7.8 3 2 5 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24987.1 - 1.5e-15 55.7 0.2 0.15 12.7 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat DUF5049 PF16468.5 EGG24987.1 - 3.2e-06 27.0 0.2 3 7.8 0.0 5.1 3 1 2 5 5 5 3 Domain of unknown function (DUF5049) Ank PF00023.30 EGG24987.1 - 0.00011 22.5 1.2 79 4.0 0.0 6.4 4 2 3 7 7 7 0 Ankyrin repeat Ank_2 PF12796.7 EGG24988.1 - 4.8e-18 65.5 0.3 1e-07 32.4 0.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG24988.1 - 5e-11 42.9 0.5 0.0052 17.3 0.0 6.1 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG24988.1 - 7.6e-11 41.3 0.3 0.32 11.7 0.0 7.7 9 1 1 10 10 10 2 Ankyrin repeat Ank_5 PF13857.6 EGG24988.1 - 1e-10 41.7 0.3 0.75 10.2 0.0 7.1 5 3 3 8 8 8 2 Ankyrin repeats (many copies) Ank PF00023.30 EGG24988.1 - 0.035 14.6 0.0 23 5.7 0.0 4.7 5 1 0 5 5 5 0 Ankyrin repeat DUF5049 PF16468.5 EGG24988.1 - 0.19 11.6 1.1 12 5.9 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5049) Insulin PF00049.18 EGG24988.1 - 0.4 11.7 2.0 0.58 11.2 0.1 2.2 2 1 0 2 2 2 0 Insulin/IGF/Relaxin family PTPA PF03095.15 EGG24990.1 - 1.1e-116 389.5 0.2 1.4e-116 389.2 0.2 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RasGEF PF00617.19 EGG24991.1 - 2.7e-54 184.1 0.3 1e-53 182.2 0.3 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGG24991.1 - 4.8e-20 71.8 0.7 4.8e-20 71.8 0.7 4.1 6 0 0 6 6 6 1 RasGEF N-terminal motif F-box-like PF12937.7 EGG24991.1 - 1.3e-10 41.0 1.3 3.6e-10 39.6 1.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGG24991.1 - 7.4e-08 32.1 1.2 1.8e-07 30.9 1.2 1.7 1 0 0 1 1 1 1 F-box domain Menin PF05053.13 EGG24991.1 - 0.26 9.6 3.2 0.5 8.7 3.2 1.4 1 0 0 1 1 1 0 Menin Apis_Csd PF11671.8 EGG24991.1 - 0.68 9.9 12.3 2.2 8.3 12.3 1.9 1 0 0 1 1 1 0 Complementary sex determiner protein Coilin_N PF15862.5 EGG24993.1 - 0.00091 19.0 7.1 0.0025 17.6 7.1 1.7 1 1 0 1 1 1 1 Coilin N-terminus Presenilin PF01080.17 EGG24993.1 - 0.0039 16.0 11.6 0.0048 15.7 11.6 1.2 1 0 0 1 1 1 1 Presenilin Apt1 PF10351.9 EGG24993.1 - 0.009 14.9 37.3 0.012 14.5 37.3 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain CCDC84 PF14968.6 EGG24993.1 - 3.5 7.1 14.2 3.8 7.0 14.2 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 RIFIN PF02009.16 EGG24993.1 - 8.2 6.2 6.5 9.7 6.0 6.5 1.1 1 0 0 1 1 1 0 Rifin Dicty_CTDC PF00526.18 EGG24995.1 - 5.5e-05 23.0 8.4 5.5e-05 23.0 8.4 13.0 14 0 0 14 14 14 4 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGG24995.1 - 0.2 11.5 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 PA14 domain ADH_zinc_N PF00107.26 EGG24996.1 - 1e-13 51.4 0.0 1.9e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG24996.1 - 2.4e-06 27.4 0.4 6.2e-06 26.1 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGG24996.1 - 0.017 16.2 0.0 0.035 15.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DEAD PF00270.29 EGG24997.1 - 3.5e-53 180.0 0.0 5.6e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGG24997.1 - 1e-32 112.8 0.0 4.1e-30 104.4 0.0 3.1 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGG24997.1 - 4.5e-06 26.8 0.0 9.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit LRR_8 PF13855.6 EGG24998.1 - 0.00068 19.3 0.2 0.0038 17.0 0.0 2.3 2 0 0 2 2 2 1 Leucine rich repeat EGF_2 PF07974.13 EGG24998.1 - 0.039 14.3 11.7 0.093 13.1 11.7 1.7 1 0 0 1 1 1 0 EGF-like domain Metallothio_5 PF02067.15 EGG24998.1 - 3.3 7.9 9.6 7.7 6.7 9.6 1.6 1 0 0 1 1 1 0 Metallothionein family 5 EB PF01683.18 EGG24999.1 - 0.0005 20.3 4.0 0.0013 19.0 4.0 1.7 1 0 0 1 1 1 1 EB module EGF_2 PF07974.13 EGG24999.1 - 0.011 16.1 11.4 0.023 15.0 11.4 1.5 1 0 0 1 1 1 0 EGF-like domain LRR_8 PF13855.6 EGG24999.1 - 0.035 13.9 2.6 0.085 12.6 0.2 2.9 4 0 0 4 4 4 0 Leucine rich repeat GRAM PF02893.20 EGG24999.1 - 0.044 13.7 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 GRAM domain DUF3042 PF11240.8 EGG24999.1 - 0.12 12.4 1.6 0.24 11.5 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) hEGF PF12661.7 EGG24999.1 - 0.7 10.6 9.6 2.5 8.9 9.6 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF Metallothio_5 PF02067.15 EGG24999.1 - 4.3 7.5 9.1 9.6 6.4 9.1 1.5 1 0 0 1 1 1 0 Metallothionein family 5 PH PF00169.29 EGG25000.1 - 1.9e-15 57.2 0.4 4.8e-15 56.0 0.4 1.6 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 EGG25000.1 - 1.2e-05 25.4 0.1 2.2e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGG25000.1 - 2.4e-05 24.5 0.1 5.8e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 EGG25000.1 - 0.015 15.6 0.2 0.043 14.1 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain PH_16 PF17838.1 EGG25000.1 - 0.055 13.3 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 PH domain PH_11 PF15413.6 EGG25000.1 - 0.23 11.9 9.6 0.059 13.8 2.5 2.9 3 1 0 3 3 3 0 Pleckstrin homology domain FAD_binding_4 PF01565.23 EGG25001.1 - 3.4e-33 114.3 0.2 5.5e-33 113.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGG25001.1 - 3.3e-11 43.1 0.4 1.3e-10 41.1 0.1 2.2 2 0 0 2 2 2 1 Berberine and berberine like Beta_helix_2 PF18835.1 EGG25001.1 - 0.016 15.0 2.5 2.1 8.2 0.4 3.0 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase Glyco_transf_8 PF01501.20 EGG25002.1 - 8.6e-06 25.5 8.6 4.9e-05 23.0 1.5 2.3 1 1 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGG25002.1 - 0.016 14.6 0.5 0.027 13.8 0.5 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative zf-LITAF-like PF10601.9 EGG25002.1 - 0.16 12.3 0.3 0.3 11.4 0.3 1.5 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain TAXi_C PF14541.6 EGG25003.1 - 1.5e-11 44.4 0.2 2e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Asp PF00026.23 EGG25003.1 - 1.8e-05 24.3 2.0 0.00033 20.2 2.0 2.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease adh_short PF00106.25 EGG25004.1 - 2.9e-40 137.8 0.0 3.9e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG25004.1 - 6.4e-30 104.4 0.0 8.1e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG25004.1 - 1.1e-09 38.5 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGG25004.1 - 3.1e-06 26.8 0.0 4e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGG25004.1 - 0.0075 16.2 0.0 0.012 15.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EGG25004.1 - 0.0093 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGG25004.1 - 0.022 14.2 0.2 0.094 12.1 0.0 2.1 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EGG25004.1 - 0.033 13.7 0.0 0.091 12.3 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Eno-Rase_NADH_b PF12242.8 EGG25004.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase E1-E2_ATPase PF00122.20 EGG25005.1 - 2.8e-49 167.1 4.7 2.8e-49 167.1 4.7 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGG25005.1 - 5.8e-40 137.8 0.1 1.2e-39 136.8 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGG25005.1 - 9.1e-24 83.7 8.1 5.3e-12 46.0 0.1 5.0 5 0 0 5 5 5 3 Heavy-metal-associated domain HAD PF12710.7 EGG25005.1 - 0.00017 22.0 0.0 0.00032 21.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGG25005.1 - 0.00078 19.3 0.2 0.054 13.2 0.1 2.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF996 PF06195.13 EGG25005.1 - 1 9.6 11.3 0.41 10.9 3.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Ribosomal_S14 PF00253.21 EGG25006.1 - 0.00042 20.0 0.1 0.88 9.4 0.0 2.6 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e CCDC168_N PF15804.5 EGG25006.1 - 0.0016 18.4 0.1 0.0019 18.1 0.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 168 Peptidase_M48_N PF16491.5 EGG25007.1 - 1.5e-58 197.7 12.9 1.5e-58 197.7 12.9 2.3 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Glyco_transf_10 PF00852.19 EGG25007.1 - 1e-36 126.3 0.8 2.3e-36 125.1 0.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Peptidase_M48 PF01435.18 EGG25007.1 - 2.6e-34 118.7 0.0 4.9e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Cyt_bd_oxida_II PF02322.15 EGG25007.1 - 0.00085 18.8 3.1 0.00085 18.8 3.1 1.7 2 0 0 2 2 2 1 Cytochrome bd terminal oxidase subunit II SprT-like PF10263.9 EGG25007.1 - 0.0096 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 SprT-like family DUF768 PF05589.11 EGG25007.1 - 0.77 9.8 1.9 8.6 6.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF768) FNIP PF05725.12 EGG25008.1 - 1.6e-12 47.3 15.1 0.069 13.3 0.5 8.9 8 2 1 9 9 9 6 FNIP Repeat AP4E_app_platf PF14807.6 EGG25008.1 - 0.16 12.4 0.3 0.43 11.0 0.3 1.7 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform SSP160 PF06933.11 EGG25008.1 - 5.8 5.0 13.3 7.9 4.5 13.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Copine PF07002.16 EGG25009.1 - 9.8e-38 129.8 0.0 9.8e-38 129.8 0.0 2.4 3 0 0 3 3 3 1 Copine C2 PF00168.30 EGG25009.1 - 4e-08 33.5 0.1 4.7e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 C2 domain RRM_1 PF00076.22 EGG25010.1 - 3.9e-66 218.8 4.3 1.1e-16 60.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EGG25010.1 - 4.2e-11 42.8 0.5 4.2e-11 42.8 0.5 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 EGG25010.1 - 2.3e-05 24.3 1.3 5.6 7.0 0.1 4.4 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EGG25010.1 - 0.1 12.8 0.1 0.1 12.8 0.1 4.4 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Ras PF00071.22 EGG25011.1 - 4.7e-52 175.9 0.2 5.4e-52 175.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG25011.1 - 9e-19 67.9 0.0 1.6e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG25011.1 - 2.5e-09 36.8 0.1 3.3e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG25011.1 - 0.00017 21.2 0.1 0.00026 20.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGG25011.1 - 0.0096 16.0 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EGG25011.1 - 0.02 14.9 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 EGG25011.1 - 0.026 14.4 0.1 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF3568 PF12092.8 EGG25011.1 - 0.033 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Pkinase_Tyr PF07714.17 EGG25012.1 - 1.2e-60 204.9 0.0 5.6e-53 179.9 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EGG25012.1 - 1.6e-43 149.0 0.0 5.2e-41 140.8 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain SPRY PF00622.28 EGG25012.1 - 6.5e-25 87.6 6.2 3.3e-18 65.9 0.4 4.1 2 1 1 3 3 3 3 SPRY domain SAM_2 PF07647.17 EGG25012.1 - 1.4e-18 66.8 0.0 3.8e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGG25012.1 - 1.3e-16 60.7 0.0 3.1e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 EGG25012.1 - 0.0038 16.0 0.0 0.0038 16.0 0.0 3.3 4 0 0 4 4 4 1 Fungal protein kinase DUF2971 PF11185.8 EGG25012.1 - 4.5 8.5 6.5 22 6.3 0.7 4.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2971) I-set PF07679.16 EGG25014.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Myb_DNA-bind_7 PF15963.5 EGG25015.1 - 4.3e-27 93.8 0.9 4.3e-27 93.8 0.9 4.0 3 1 2 5 5 5 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EGG25015.1 - 7.2e-07 29.3 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MGC-24 PF05283.11 EGG25015.1 - 9.4 6.7 16.1 3.2 8.2 3.3 2.8 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PseudoU_synth_1 PF01416.20 EGG25016.1 - 1.6e-12 47.9 0.0 1.2e-09 38.6 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 EGG25016.1 - 0.032 14.1 1.3 0.049 13.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF3439 PF11921.8 EGG25016.1 - 0.13 12.2 10.7 0.19 11.7 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SAP18 PF06487.12 EGG25017.1 - 8.1e-23 81.2 11.6 5.8e-22 78.4 8.9 3.2 2 1 0 2 2 2 1 Sin3 associated polypeptide p18 (SAP18) SSP160 PF06933.11 EGG25017.1 - 0.073 11.3 7.1 0.14 10.4 7.1 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 E1-E2_ATPase PF00122.20 EGG25018.1 - 3.4e-33 114.7 3.6 5.6e-33 114.0 0.1 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Abhydrolase_1 PF00561.20 EGG25018.1 - 1e-23 84.3 0.2 2.9e-23 82.8 0.2 1.9 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase PF00702.26 EGG25018.1 - 8.6e-17 62.1 0.0 2.8e-11 44.1 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 EGG25018.1 - 3.1e-10 40.2 0.0 1.2e-09 38.4 0.0 2.1 1 0 0 1 1 1 1 P5-type ATPase cation transporter Abhydrolase_6 PF12697.7 EGG25018.1 - 7.9e-08 33.2 0.0 1.7e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG25018.1 - 2.9e-06 26.7 0.0 9.9e-06 25.0 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cation_ATPase_N PF00690.26 EGG25018.1 - 0.00058 19.5 0.0 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Init_tRNA_PT PF04179.12 EGG25018.1 - 0.081 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Rit1 DUSP-like domain DNase_II PF03265.15 EGG25019.1 - 0.00031 20.2 0.1 0.00034 20.0 0.1 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II TIG PF01833.24 EGG25020.1 - 3.3e-29 100.8 115.4 6.1e-05 23.0 4.1 12.5 11 2 2 13 13 13 11 IPT/TIG domain EGF_2 PF07974.13 EGG25020.1 - 4.1e-06 27.1 13.5 8.6e-06 26.0 13.5 1.6 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGG25020.1 - 8.6e-05 22.5 12.2 0.00023 21.2 12.2 1.8 1 0 0 1 1 1 1 Tenascin EGF domain EGF PF00008.27 EGG25020.1 - 0.00055 20.2 7.1 0.0015 18.8 7.1 1.8 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 EGG25020.1 - 0.057 14.1 5.3 0.18 12.5 5.3 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF Laminin_EGF PF00053.24 EGG25020.1 - 1.5 9.0 10.8 3.5 7.8 10.8 1.6 1 0 0 1 1 1 0 Laminin EGF domain Abhydrolase_1 PF00561.20 EGG25021.1 - 2.1e-21 76.8 0.4 3.4e-21 76.1 0.4 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG25021.1 - 8.2e-06 26.6 0.0 1.1e-05 26.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG25021.1 - 7.3e-05 22.2 0.0 0.0004 19.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EGG25021.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Y_phosphatase3 PF13350.6 EGG25023.1 - 5.1e-41 141.2 0.1 2.6e-27 96.3 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGG25023.1 - 0.0023 17.5 0.1 0.0067 16.0 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family DUF1631 PF07793.11 EGG25024.1 - 0.65 8.4 5.0 1 7.7 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) ANAPC4_WD40 PF12894.7 EGG25026.1 - 0.0068 16.7 3.3 3 8.2 0.0 4.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SPX PF03105.19 EGG25026.1 - 0.028 14.3 4.8 0.044 13.7 4.8 1.3 1 0 0 1 1 1 0 SPX domain DUF1180 PF06679.12 EGG25026.1 - 1.6 9.1 3.6 0.55 10.6 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Macoilin PF09726.9 EGG25026.1 - 1.8 7.0 11.1 3.1 6.3 11.1 1.3 1 0 0 1 1 1 0 Macoilin family CNH PF00780.22 EGG25027.1 - 0.24 11.0 0.0 0.31 10.6 0.0 1.1 1 0 0 1 1 1 0 CNH domain Vps39_2 PF10367.9 EGG25028.1 - 1.7e-28 99.2 0.3 1.7e-28 99.2 0.3 2.7 2 1 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 EGG25028.1 - 0.00049 20.0 2.4 0.00049 20.0 2.4 2.6 2 1 0 2 2 2 1 Region in Clathrin and VPS ArAE_1_C PF11728.8 EGG25028.1 - 0.012 15.7 1.5 0.012 15.7 1.5 2.4 2 1 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain SUIM_assoc PF16619.5 EGG25028.1 - 0.034 14.2 10.4 0.066 13.3 9.2 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-C3HC4_3 PF13920.6 EGG25028.1 - 0.12 12.2 0.3 0.27 11.1 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.9 EGG25028.1 - 0.19 12.0 1.4 0.74 10.1 1.4 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF4808 PF16066.5 EGG25028.1 - 0.24 12.0 7.1 0.59 10.7 1.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) TFIIA PF03153.13 EGG25028.1 - 0.24 11.4 14.4 0.3 11.1 3.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TPR_8 PF13181.6 EGG25028.1 - 1 9.7 4.7 9.6 6.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MRP-S26 PF14943.6 EGG25028.1 - 2.4 8.0 7.9 0.78 9.6 4.4 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Piwi PF02171.17 EGG25030.1 - 2.5e-72 243.7 1.2 4e-72 243.0 1.2 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 EGG25030.1 - 7.9e-26 90.5 1.4 2.3e-25 89.0 1.4 1.7 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 EGG25030.1 - 0.0045 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain Macoilin PF09726.9 EGG25030.1 - 0.64 8.5 8.4 0.94 8.0 8.4 1.2 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 EGG25031.1 - 1.9e-14 53.8 9.7 0.0038 18.0 0.0 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGG25031.1 - 4.6e-10 39.7 0.9 0.0014 18.8 0.0 4.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGG25031.1 - 0.1 12.6 0.0 16 5.6 0.0 3.2 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region RRM_1 PF00076.22 EGG25032.1 - 4.1e-26 90.6 5.3 3.6e-11 42.7 0.1 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGG25032.1 - 0.011 15.7 0.6 0.081 12.9 0.1 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Nop53 PF07767.11 EGG25032.1 - 0.49 9.7 22.6 1.1 8.5 22.6 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) UPF0242 PF06785.11 EGG25032.1 - 2.9 8.0 26.8 8.1 6.5 26.8 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ank_2 PF12796.7 EGG25033.1 - 1.1e-21 77.2 7.3 0.00017 22.1 0.0 7.9 2 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG25033.1 - 3.2e-12 46.4 1.9 0.024 15.0 0.0 8.0 5 2 3 9 9 9 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG25033.1 - 1.4e-09 38.3 8.3 8.6 7.1 0.0 9.9 7 5 5 12 12 12 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG25033.1 - 2.9e-08 33.3 4.3 46 5.1 0.0 10.5 11 1 1 12 12 12 0 Ankyrin repeat DUF3447 PF11929.8 EGG25033.1 - 1e-05 25.4 11.3 1 9.4 0.4 6.1 3 3 3 6 6 6 3 Domain of unknown function (DUF3447) Ank PF00023.30 EGG25033.1 - 0.082 13.4 2.5 1.1e+02 3.5 0.2 6.1 6 2 1 7 7 7 0 Ankyrin repeat Mif2_N PF15624.6 EGG25033.1 - 0.13 13.0 0.0 12 6.6 0.0 2.3 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Ank_2 PF12796.7 EGG25034.1 - 8.3e-23 80.8 2.0 4.7e-06 27.1 0.0 5.0 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG25034.1 - 1.8e-14 53.9 6.7 0.00094 19.7 0.0 6.9 6 1 2 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG25034.1 - 6.1e-13 48.7 3.9 0.43 11.0 0.2 8.5 5 2 3 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG25034.1 - 2.9e-12 45.6 12.4 8 7.4 0.0 11.6 10 2 3 13 13 13 2 Ankyrin repeat Ank PF00023.30 EGG25034.1 - 4.9e-05 23.6 0.9 17 6.1 0.1 6.0 3 2 2 5 5 5 2 Ankyrin repeat DUF3447 PF11929.8 EGG25034.1 - 0.013 15.5 12.5 0.32 11.0 0.1 6.0 2 2 5 7 7 7 0 Domain of unknown function (DUF3447) DUF5049 PF16468.5 EGG25034.1 - 0.015 15.1 0.0 0.69 9.8 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5049) DUF249 PF03158.13 EGG25034.1 - 0.049 13.3 5.2 0.45 10.2 0.7 3.8 3 3 0 3 3 3 0 Multigene family 530 protein DUF3969 PF13108.6 EGG25035.1 - 0.11 12.5 1.9 45 4.1 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3969) HTH_Tnp_Tc3_2 PF01498.18 EGG25035.1 - 0.4 11.0 4.8 0.54 10.5 0.6 2.3 2 0 0 2 2 2 0 Transposase GAIN_A PF18619.1 EGG25035.1 - 3.5 7.9 12.9 17 5.7 0.1 5.0 4 1 0 4 4 4 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A DUF3433 PF11915.8 EGG25035.1 - 3.6 8.1 6.8 21 5.7 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3433) ALMT PF11744.8 EGG25038.1 - 1.2e-37 129.9 16.3 1.2e-37 129.9 16.3 5.0 6 0 0 6 6 6 1 Aluminium activated malate transporter FUSC_2 PF13515.6 EGG25038.1 - 1.3e-17 64.1 12.8 1.3e-17 64.1 12.8 5.5 3 2 1 4 4 4 2 Fusaric acid resistance protein-like FUSC PF04632.12 EGG25038.1 - 6.8e-11 41.4 7.6 6.8e-11 41.4 7.6 1.9 2 0 0 2 2 2 1 Fusaric acid resistance protein family Ctr PF04145.15 EGG25038.1 - 0.63 10.7 7.4 49 4.5 4.2 3.6 3 0 0 3 3 3 0 Ctr copper transporter family EPL1 PF10513.9 EGG25038.1 - 0.97 9.8 20.2 4.6 7.6 6.5 3.2 3 0 0 3 3 3 0 Enhancer of polycomb-like G0-G1_switch_2 PF15103.6 EGG25038.1 - 3.6 8.0 6.9 55 4.3 4.0 3.8 3 0 0 3 3 3 0 G0/G1 switch protein 2 Mpp10 PF04006.12 EGG25039.1 - 0.00085 17.9 11.5 0.0013 17.3 11.5 1.2 1 0 0 1 1 1 1 Mpp10 protein Cullin PF00888.22 EGG25040.1 - 1.8e-220 733.7 28.3 2.7e-220 733.2 28.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGG25040.1 - 7.5e-29 99.6 4.1 4.1e-28 97.2 4.1 2.4 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.11 EGG25040.1 - 0.087 12.8 3.8 0.15 12.0 0.4 2.8 2 1 0 3 3 3 0 HbrB-like DUF2779 PF11074.8 EGG25040.1 - 1.7 9.1 5.8 0.47 10.9 0.3 3.0 3 1 1 4 4 4 0 Domain of unknown function(DUF2779) Senescence PF06911.12 EGG25041.1 - 6.7e-27 95.0 7.6 1.1e-26 94.3 7.6 1.3 1 0 0 1 1 1 1 Senescence-associated protein Dynein_C PF18199.1 EGG25041.1 - 0.0094 15.2 0.5 0.014 14.6 0.5 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Synuclein PF01387.17 EGG25041.1 - 0.35 11.1 4.9 0.86 9.8 0.8 2.5 1 1 1 2 2 2 0 Synuclein Rhomboid PF01694.22 EGG25042.1 - 6e-25 88.0 12.7 6e-25 88.0 12.7 1.9 2 1 0 2 2 2 1 Rhomboid family Rhomboid PF01694.22 EGG25043.1 - 4.9e-21 75.3 10.5 4.9e-21 75.3 10.5 1.8 2 0 0 2 2 2 1 Rhomboid family YfhO PF09586.10 EGG25043.1 - 2.5 6.2 8.4 0.8 7.9 2.7 2.1 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Ank_2 PF12796.7 EGG25044.1 - 9.7e-19 67.8 6.1 0.00017 22.1 0.0 6.5 5 2 2 7 7 7 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG25044.1 - 1.9e-16 60.2 7.7 0.12 13.0 0.0 11.1 8 3 2 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG25044.1 - 4.1e-11 42.1 0.9 3.9 8.4 0.0 10.4 12 0 0 12 12 12 1 Ankyrin repeat Ank_5 PF13857.6 EGG25044.1 - 3.3e-08 33.6 0.2 6.7 7.2 0.0 7.1 5 2 2 7 7 7 2 Ankyrin repeats (many copies) BMC PF00936.19 EGG25044.1 - 0.035 14.1 0.3 24 5.0 0.0 4.2 5 0 0 5 5 5 0 BMC domain DDE_Tnp_1_7 PF13843.6 EGG25045.1 - 3.8e-27 95.5 3.5 3.8e-27 95.5 3.5 3.6 3 1 0 3 3 3 1 Transposase IS4 Apt1 PF10351.9 EGG25045.1 - 0.098 11.5 22.5 1.6 7.5 22.5 2.2 1 1 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EGG25045.1 - 0.47 8.9 24.4 1 7.9 24.4 1.5 1 0 0 1 1 1 0 Macoilin family EGF_2 PF07974.13 EGG25046.1 - 0.013 15.9 12.5 0.03 14.7 12.5 1.7 1 0 0 1 1 1 0 EGF-like domain fn3 PF00041.21 EGG25046.1 - 0.064 13.6 5.2 0.12 12.8 0.1 3.5 4 0 0 4 4 4 0 Fibronectin type III domain CBX7_C PF17218.3 EGG25046.1 - 4.8 7.0 10.0 5.3 6.8 0.0 3.7 2 0 0 2 2 2 0 CBX family C-terminal motif PAH PF02671.21 EGG25047.1 - 0.00087 19.4 0.1 0.0036 17.4 0.1 2.1 1 0 0 1 1 1 1 Paired amphipathic helix repeat Spt5_N PF11942.8 EGG25047.1 - 3.6 8.6 19.6 15 6.6 16.4 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FAM176 PF14851.6 EGG25047.1 - 6.4 6.4 10.4 22 4.7 5.9 2.8 2 0 0 2 2 2 0 FAM176 family DUF2362 PF10154.9 EGG25048.1 - 9.3e-71 239.3 47.9 1.2e-34 120.1 0.1 4.4 1 1 2 3 3 3 3 Uncharacterized conserved protein (DUF2362) NDUF_B6 PF09782.9 EGG25049.1 - 0.041 14.0 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DHHC PF01529.20 EGG25049.1 - 0.077 13.1 6.4 0.11 12.6 0.4 2.7 2 1 0 2 2 2 0 DHHC palmitoyltransferase Yip1 PF04893.17 EGG25049.1 - 0.42 10.3 8.3 0.34 10.6 2.9 2.4 2 1 0 2 2 2 0 Yip1 domain Gelsolin PF00626.22 EGG25050.1 - 5.4e-71 234.5 0.7 1.9e-17 62.9 0.0 8.0 7 0 0 7 7 7 7 Gelsolin repeat LRR_8 PF13855.6 EGG25050.1 - 2.8e-17 62.2 33.6 0.0003 20.5 2.0 5.3 4 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 EGG25050.1 - 1.6e-12 47.4 42.2 0.001 19.4 3.6 6.1 5 1 2 7 7 7 5 Leucine Rich repeats (2 copies) VHP PF02209.19 EGG25050.1 - 1.4e-09 37.8 2.5 1.4e-09 37.8 2.5 2.0 2 0 0 2 2 2 1 Villin headpiece domain GIY-YIG PF01541.24 EGG25050.1 - 0.086 13.1 1.2 3.1 8.1 0.0 3.6 4 0 0 4 4 4 0 GIY-YIG catalytic domain TIG PF01833.24 EGG25051.1 - 1e-08 35.1 14.3 0.00022 21.2 1.4 4.1 4 0 0 4 4 4 2 IPT/TIG domain EGF_2 PF07974.13 EGG25051.1 - 0.00085 19.6 11.6 0.00085 19.6 11.6 2.0 2 0 0 2 2 2 1 EGF-like domain Asp_protease PF09668.10 EGG25051.1 - 0.0083 15.9 0.9 0.025 14.4 0.3 2.0 2 0 0 2 2 2 1 Aspartyl protease Laminin_EGF PF00053.24 EGG25051.1 - 0.029 14.5 6.0 0.077 13.1 6.0 1.6 1 0 0 1 1 1 0 Laminin EGF domain LRR_6 PF13516.6 EGG25051.1 - 1.7 8.9 4.6 25 5.3 0.2 3.6 3 0 0 3 3 3 0 Leucine Rich repeat TIG PF01833.24 EGG25052.1 - 2.2e-23 82.1 111.6 1.7e-05 24.8 2.2 11.7 11 1 1 12 12 12 10 IPT/TIG domain T2SS-T3SS_pil_N PF13629.6 EGG25052.1 - 0.54 10.0 6.3 8.4 6.2 0.4 3.3 2 0 0 2 2 2 0 Pilus formation protein N terminal region DUF4333 PF14230.6 EGG25052.1 - 9.9 6.5 9.0 36 4.7 4.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4333) BUD22 PF09073.10 EGG25053.1 - 6e-09 35.8 69.3 6e-09 35.8 69.3 3.2 1 1 1 2 2 2 1 BUD22 PH PF00169.29 EGG25053.1 - 9.5e-09 35.7 1.7 2.4e-08 34.4 0.0 2.6 2 1 1 3 3 3 1 PH domain F_actin_bind PF08919.10 EGG25055.1 - 7.1e-20 71.2 1.2 1.1e-19 70.5 1.2 1.3 1 0 0 1 1 1 1 F-actin binding Focal_AT PF03623.13 EGG25055.1 - 0.052 13.5 0.4 0.11 12.5 0.2 1.7 2 1 0 2 2 2 0 Focal adhesion targeting region TFA2_Winged_2 PF18121.1 EGG25055.1 - 0.11 12.2 0.1 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 RNA12 PF10443.9 EGG25056.1 - 9e-54 182.9 0.0 9.8e-28 97.1 0.1 3.8 3 1 1 4 4 4 2 RNA12 protein ATPase_2 PF01637.18 EGG25056.1 - 5.2e-07 29.8 0.0 5.2e-07 29.8 0.0 2.7 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea G-patch PF01585.23 EGG25056.1 - 5.7e-07 29.3 3.8 1.1e-06 28.5 3.8 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EGG25056.1 - 0.0003 20.5 0.0 0.0014 18.4 0.0 2.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_22 PF13401.6 EGG25056.1 - 0.008 16.5 0.0 0.045 14.0 0.0 2.3 1 0 0 1 1 1 1 AAA domain zf-U1 PF06220.12 EGG25056.1 - 0.019 14.7 1.1 0.048 13.4 1.1 1.7 1 0 0 1 1 1 0 U1 zinc finger AAA_29 PF13555.6 EGG25056.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGG25056.1 - 0.084 13.3 0.0 0.31 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Laminin_EGF PF00053.24 EGG25057.1 - 2.1e-05 24.6 27.6 0.011 15.9 5.5 3.4 3 0 0 3 3 3 2 Laminin EGF domain DUF5050 PF16472.5 EGG25057.1 - 0.012 14.8 2.8 0.16 11.2 2.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5050) EB PF01683.18 EGG25057.1 - 0.032 14.5 11.2 0.032 14.5 11.2 3.5 3 0 0 3 3 3 0 EB module EGF_2 PF07974.13 EGG25057.1 - 2.9 8.3 30.1 0.74 10.2 3.7 3.7 3 1 0 3 3 3 0 EGF-like domain hEGF PF12661.7 EGG25057.1 - 6 7.7 17.1 25 5.7 0.3 5.0 3 1 0 3 3 3 0 Human growth factor-like EGF zf-U1 PF06220.12 EGG25058.1 - 8.9e-20 70.2 4.0 1.3e-19 69.6 4.0 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.8 EGG25058.1 - 0.057 13.7 6.3 0.52 10.7 6.3 2.1 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Methyltransf_7 PF03492.15 EGG25058.1 - 0.086 12.0 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase zf-met PF12874.7 EGG25058.1 - 0.2 12.1 2.0 2.3 8.7 2.0 2.1 1 1 0 1 1 1 0 Zinc-finger of C2H2 type Rieske PF00355.26 EGG25059.1 - 0.037 14.0 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain DUF1864 PF08933.11 EGG25059.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) FDX-ACB PF03147.14 EGG25059.1 - 0.16 12.4 0.1 0.63 10.5 0.0 1.9 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain WWE PF02825.20 EGG25060.1 - 5.3e-06 26.9 4.5 7e-06 26.5 2.6 2.3 2 0 0 2 2 2 1 WWE domain NST1 PF13945.6 EGG25060.1 - 0.01 16.0 7.3 0.021 14.9 7.3 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator SAP PF02037.27 EGG25061.1 - 1.6e-09 37.3 2.4 4.3e-06 26.3 1.5 2.6 2 0 0 2 2 2 2 SAP domain HTH_26 PF13443.6 EGG25061.1 - 0.00032 21.1 2.0 0.12 12.9 0.1 3.2 4 0 0 4 4 4 2 Cro/C1-type HTH DNA-binding domain BAR PF03114.18 EGG25061.1 - 0.0018 18.0 1.8 0.04 13.6 0.3 2.2 2 0 0 2 2 2 1 BAR domain HeH PF12949.7 EGG25061.1 - 0.012 15.3 3.1 0.017 14.9 0.0 2.7 3 0 0 3 3 3 0 HeH/LEM domain Armet PF10208.9 EGG25061.1 - 0.11 12.5 0.8 2.7 7.9 0.1 2.6 1 1 1 2 2 2 0 Degradation arginine-rich protein for mis-folding Myosin_head PF00063.21 EGG25063.1 - 2e-248 826.1 6.7 2.5e-248 825.8 6.7 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGG25063.1 - 2.9e-41 141.2 1.3 5.6e-41 140.3 1.3 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EGG25063.1 - 1.7e-16 59.6 0.1 3.4e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGG25063.1 - 7.4e-14 51.3 0.0 1.5e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGG25063.1 - 3.1e-09 36.4 0.0 7.4e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 EGG25063.1 - 0.031 14.6 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGG25063.1 - 0.039 14.2 0.0 0.16 12.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 EGG25063.1 - 0.056 13.0 0.2 4.1 6.9 0.0 2.9 2 1 1 3 3 3 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.12 EGG25063.1 - 0.059 12.6 0.7 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 EGG25063.1 - 0.061 13.7 0.2 0.3 11.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 EGG25063.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EGG25063.1 - 0.18 12.3 0.7 0.62 10.6 0.1 2.1 2 0 0 2 2 2 0 ABC transporter FYVE PF01363.21 EGG25064.1 - 2.7e-18 65.9 13.7 4.8e-18 65.1 13.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger Arrestin_N PF00339.29 EGG25064.1 - 1e-16 61.3 2.6 4.9e-13 49.4 0.2 3.2 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGG25064.1 - 2e-15 57.4 0.3 7.5e-14 52.3 0.1 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 EGG25064.1 - 0.0049 16.1 0.6 0.22 10.7 0.0 2.8 2 1 1 3 3 3 1 Rgp1 Raco_middle PF17651.1 EGG25064.1 - 0.066 12.9 0.1 0.29 10.8 0.1 1.9 2 0 0 2 2 2 0 RACo middle region FYVE_2 PF02318.16 EGG25064.1 - 0.084 13.1 9.6 0.19 11.9 9.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Ank_2 PF12796.7 EGG25065.1 - 8.1e-18 64.8 7.0 1.5e-07 31.9 0.2 5.8 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG25065.1 - 9.3e-17 60.9 8.8 0.097 13.0 0.0 8.8 3 3 7 10 10 10 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG25065.1 - 1.3e-14 54.3 8.1 0.0015 19.1 0.1 8.2 5 3 4 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG25065.1 - 2.4e-10 39.7 4.5 4.2 8.2 0.0 9.8 10 0 0 10 10 10 2 Ankyrin repeat Ank PF00023.30 EGG25065.1 - 0.13 12.8 0.1 77 4.0 0.1 4.6 3 2 0 3 3 3 0 Ankyrin repeat DUF1843 PF08898.10 EGG25065.1 - 0.14 12.7 0.0 0.4 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) RICTOR_phospho PF14665.6 EGG25066.1 - 0.00023 21.5 1.0 0.0016 18.7 0.1 2.2 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, phosphorylation-site TFIIA PF03153.13 EGG25067.1 - 0.029 14.4 19.2 0.03 14.3 19.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EGG25067.1 - 0.031 14.9 14.0 0.044 14.4 14.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDK5_activator PF03261.15 EGG25067.1 - 0.033 13.7 6.9 0.045 13.3 6.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein G0-G1_switch_2 PF15103.6 EGG25067.1 - 0.08 13.4 1.1 0.13 12.7 1.1 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF2722 PF10846.8 EGG25067.1 - 0.082 11.8 17.4 0.083 11.8 17.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RP-C_C PF11800.8 EGG25067.1 - 0.098 12.7 3.3 0.12 12.4 3.3 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region ABC2_membrane_3 PF12698.7 EGG25067.1 - 0.11 11.6 10.4 0.14 11.3 10.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Spt20 PF12090.8 EGG25067.1 - 0.81 9.3 31.0 1.2 8.7 31.0 1.3 1 0 0 1 1 1 0 Spt20 family DUF1980 PF09323.10 EGG25067.1 - 1.7 8.5 7.4 2.6 7.9 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Presenilin PF01080.17 EGG25067.1 - 2 7.1 8.1 2.2 7.0 8.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.6 EGG25067.1 - 2.9 5.7 18.0 3.4 5.5 18.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Nramp PF01566.18 EGG25068.1 - 4.2e-123 410.8 13.1 4.2e-123 410.8 13.1 1.8 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein HemY_N PF07219.13 EGG25068.1 - 0.06 13.6 4.7 3.9 7.7 0.5 2.8 2 0 0 2 2 2 0 HemY protein N-terminus PCNA_N PF00705.18 EGG25069.1 - 0.011 15.4 0.1 0.068 12.9 0.1 2.1 1 1 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EGG25069.1 - 0.025 14.8 0.0 0.06 13.5 0.0 1.6 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, C-terminal domain Dicty_CAR PF05462.11 EGG25070.1 - 3.7e-08 32.8 20.3 5.1e-08 32.4 20.3 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 EGG25070.1 - 0.042 13.1 17.4 0.074 12.3 17.4 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) UPF0203 PF05254.12 EGG25070.1 - 0.043 14.1 2.2 1.2 9.4 2.2 2.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) CX9C PF16860.5 EGG25070.1 - 0.26 11.3 4.4 0.57 10.2 0.6 2.3 1 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ATP-synt_8 PF00895.20 EGG25070.1 - 2.4 8.7 0.0 2.4 8.7 0.0 4.7 6 1 0 6 6 6 0 ATP synthase protein 8 Radial_spoke_3 PF06098.11 EGG25071.1 - 0.018 14.4 11.4 0.022 14.1 11.4 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 Connexin PF00029.19 EGG25071.1 - 0.26 11.0 3.4 0.3 10.8 3.4 1.2 1 0 0 1 1 1 0 Connexin GAGA_bind PF06217.12 EGG25071.1 - 0.43 10.8 7.8 0.5 10.6 7.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CAF1 PF04857.20 EGG25071.1 - 2.1 7.4 6.6 2.8 7.0 6.6 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF5352 PF17303.2 EGG25071.1 - 8.1 6.3 7.1 11 5.9 6.6 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5352) UQ_con PF00179.26 EGG25072.1 - 3.7e-19 68.8 1.2 4.2e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme zf-RanBP PF00641.18 EGG25072.1 - 0.0028 16.9 0.4 0.0064 15.8 0.4 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SR-25 PF10500.9 EGG25072.1 - 2.6 7.6 17.0 1.1 8.8 14.8 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4820 PF16091.5 EGG25072.1 - 4.5 6.6 10.0 7.8 5.8 10.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SOBP PF15279.6 EGG25072.1 - 5.3 7.6 33.6 8.7 6.8 33.6 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2072 PF09845.9 EGG25072.1 - 6.3 7.1 10.7 15 5.8 10.7 1.6 1 1 0 1 1 1 0 Zn-ribbon containing protein PA26 PF04636.13 EGG25072.1 - 6.8 5.5 10.1 9.3 5.0 10.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SLC12 PF03522.15 EGG25072.1 - 8.3 5.3 12.6 11 4.9 12.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Profilin PF00235.19 EGG25073.1 - 9.8e-05 22.6 0.1 9.8e-05 22.6 0.1 1.0 1 0 0 1 1 1 1 Profilin Profilin PF00235.19 EGG25074.1 - 0.018 15.3 0.0 0.019 15.2 0.0 1.0 1 0 0 1 1 1 0 Profilin LRR_9 PF14580.6 EGG25075.1 - 1.3e-13 50.8 0.6 2.1e-11 43.6 0.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EGG25075.1 - 2.4e-12 46.8 32.6 8.4e-06 26.0 3.1 3.1 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGG25075.1 - 2.5e-08 33.5 16.7 2.2e-05 24.1 4.9 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 EGG25075.1 - 0.00067 19.5 6.5 3.5 7.9 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 EGG25075.1 - 0.028 14.9 9.2 15 6.6 0.4 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat DUF3439 PF11921.8 EGG25075.1 - 0.12 12.4 0.3 0.2 11.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGG25075.1 - 0.72 9.8 7.3 1.3 9.0 7.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein G-gamma PF00631.22 EGG25076.1 - 1.3e-05 25.0 0.1 4.4e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 GGL domain DWNN PF08783.11 EGG25077.1 - 3.5e-30 104.1 0.3 3.5e-30 104.1 0.3 2.1 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 EGG25077.1 - 2.8e-09 36.6 12.1 2.8e-09 36.6 12.1 3.2 4 0 0 4 4 4 1 Zinc knuckle LMBR1 PF04791.16 EGG25077.1 - 0.82 8.5 3.9 1.2 8.0 3.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-CCHC PF00098.23 EGG25077.1 - 6.5 7.0 13.3 0.066 13.3 4.9 2.2 2 0 0 2 2 2 0 Zinc knuckle DZR PF12773.7 EGG25077.1 - 8.5 6.5 12.1 8.6 6.5 7.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon Cyclin_N PF00134.23 EGG25079.1 - 2.4e-20 72.6 2.9 4e-20 71.8 2.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGG25079.1 - 6.4e-07 29.5 0.3 7e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain ParA PF10609.9 EGG25080.1 - 3.7e-102 341.0 0.1 4.2e-102 340.8 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGG25080.1 - 1.4e-09 38.1 0.0 4.3e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGG25080.1 - 6.5e-07 29.4 0.2 9.7e-06 25.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EGG25080.1 - 5.3e-06 25.8 0.7 0.00011 21.5 0.3 2.2 1 1 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 EGG25080.1 - 0.00033 20.2 0.1 0.11 11.9 0.0 2.5 2 1 1 3 3 3 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 EGG25080.1 - 0.00081 19.0 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 EGG25080.1 - 0.0046 16.3 0.0 0.011 15.0 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ RsgA_GTPase PF03193.16 EGG25080.1 - 0.0066 16.4 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 EGG25080.1 - 0.074 13.4 0.1 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 EGG25080.1 - 0.13 11.4 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain CBP_BcsQ PF06564.12 EGG25080.1 - 0.14 11.6 0.0 1.1 8.7 0.0 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ SIS_2 PF13580.6 EGG25080.1 - 0.19 11.7 0.0 8.9 6.3 0.0 2.6 1 1 2 3 3 3 0 SIS domain DPM3 PF08285.11 EGG25081.1 - 2.5e-29 101.3 0.2 2.7e-29 101.2 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pkinase PF00069.25 EGG25082.1 - 4e-16 59.2 2.8 2.8e-12 46.6 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG25082.1 - 7.7e-08 31.9 0.0 6.8e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Presenilin PF01080.17 EGG25082.1 - 0.36 9.5 6.5 0.65 8.7 6.5 1.4 1 0 0 1 1 1 0 Presenilin DUF4372 PF14294.6 EGG25083.1 - 0.0063 16.6 0.4 8.8 6.6 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4372) FXa_inhibition PF14670.6 EGG25083.1 - 1.2 9.5 8.1 6.2 7.2 8.1 2.3 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site zf-CCCH PF00642.24 EGG25084.1 - 1.7e-09 37.4 18.3 1.9e-06 27.7 0.4 3.4 2 1 1 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EGG25084.1 - 3.8e-07 30.3 23.9 0.027 15.0 1.0 3.3 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EGG25084.1 - 4.6e-06 26.8 8.3 4.6e-06 26.8 8.3 3.5 2 2 2 4 4 4 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 EGG25084.1 - 1.1e-05 25.3 2.8 1.1e-05 25.3 2.8 3.1 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_4 PF18044.1 EGG25084.1 - 0.00062 19.5 17.4 0.00068 19.4 0.4 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 EGG25084.1 - 0.0015 19.2 9.2 0.0015 19.2 9.2 7.4 1 1 5 7 7 7 2 Torus domain DUF908 PF06012.12 EGG25085.1 - 2.5 7.4 14.5 4.3 6.7 14.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TFIIA PF03153.13 EGG25085.1 - 3.6 7.5 33.6 5.6 6.8 33.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCCH PF00642.24 EGG25086.1 - 1.5e-05 24.8 2.1 1.5e-05 24.8 2.1 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGG25086.1 - 0.014 16.1 1.1 0.014 16.1 1.1 3.1 3 0 0 3 3 3 0 Torus domain Mucin PF01456.17 EGG25086.1 - 0.74 9.8 6.6 1.5 8.8 6.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein AP3D1 PF06375.11 EGG25086.1 - 1.1 9.5 21.8 3.2 8.0 6.9 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 GEMIN8 PF15348.6 EGG25086.1 - 1.6 9.0 14.7 0.33 11.2 1.2 2.4 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 zf_CCCH_4 PF18345.1 EGG25086.1 - 5.7 7.1 14.2 0.18 11.9 7.0 2.1 2 0 0 2 2 2 0 Zinc finger domain RNase_H2_suC PF08615.11 EGG25087.1 - 4.2e-22 78.9 0.0 4.2e-22 78.9 0.0 3.6 2 1 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Rrp44_CSD1 PF17216.3 EGG25087.1 - 0.013 15.2 2.8 0.033 13.9 2.8 1.7 1 0 0 1 1 1 0 Rrp44-like cold shock domain VIR_N PF15912.5 EGG25087.1 - 3.8 7.0 20.6 6.6 6.2 20.6 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Menin PF05053.13 EGG25087.1 - 9.6 4.4 19.8 13 4.0 19.8 1.2 1 0 0 1 1 1 0 Menin F-box PF00646.33 EGG25088.1 - 1.3e-07 31.3 0.7 6.2e-07 29.1 0.7 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGG25088.1 - 2.3e-05 24.2 0.1 7.3e-05 22.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like DUF5051 PF16473.5 EGG25088.1 - 0.011 15.7 1.0 0.037 14.0 0.1 2.2 2 1 1 3 3 3 0 3' exoribonuclease, RNase T-like LRR_6 PF13516.6 EGG25088.1 - 0.47 10.6 4.1 41 4.6 0.1 4.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 EGG25088.1 - 5.9 7.5 13.7 0.88 10.1 2.7 4.3 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Ribosomal_L37ae PF01780.19 EGG25089.1 - 4.4e-41 138.9 9.2 4.8e-41 138.7 9.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EGG25089.1 - 0.11 12.6 4.2 0.16 12.2 4.2 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 EGG25089.1 - 0.14 12.1 4.9 0.24 11.4 4.9 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain C1_2 PF03107.16 EGG25089.1 - 0.2 12.0 4.6 0.69 10.3 4.6 1.7 1 1 0 1 1 1 0 C1 domain DUF1681 PF07933.14 EGG25090.1 - 2.3e-46 157.2 0.0 3.1e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF3276 PF11680.8 EGG25090.1 - 0.24 11.6 0.2 0.24 11.6 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) SH3_9 PF14604.6 EGG25091.1 - 1.2e-27 95.4 1.6 1.2e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EGG25091.1 - 1.1e-24 85.7 2.2 8e-14 51.0 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGG25091.1 - 1.5e-18 66.2 1.2 2.4e-08 33.5 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain Fib_alpha PF08702.10 EGG25091.1 - 0.00042 20.5 3.9 0.00042 20.5 3.9 3.8 3 1 1 4 4 4 2 Fibrinogen alpha/beta chain family MbeD_MobD PF04899.12 EGG25091.1 - 0.04 14.0 3.6 0.81 9.8 0.9 2.8 2 0 0 2 2 2 0 MbeD/MobD like HR1 PF02185.16 EGG25091.1 - 0.082 13.0 23.5 0.19 11.9 4.1 3.5 3 0 0 3 3 3 0 Hr1 repeat DivIC PF04977.15 EGG25091.1 - 0.09 12.6 22.6 0.47 10.3 2.3 3.8 4 0 0 4 4 4 0 Septum formation initiator WD40_alt PF14077.6 EGG25091.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.2 3 0 0 3 3 2 0 Alternative WD40 repeat motif ABC_tran_CTD PF16326.5 EGG25091.1 - 0.17 12.1 0.1 0.17 12.1 0.1 3.8 3 1 1 4 4 4 0 ABC transporter C-terminal domain GCN5L1 PF06320.13 EGG25091.1 - 0.96 9.6 12.6 0.36 11.0 0.8 3.2 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) CHASE3 PF05227.13 EGG25091.1 - 0.97 9.3 6.0 0.58 10.1 2.6 2.3 2 0 0 2 2 2 0 CHASE3 domain PilJ PF13675.6 EGG25091.1 - 2.6 8.1 5.6 1.4 8.9 0.4 2.8 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cas_Cas6 PF01881.16 EGG25091.1 - 2.7 8.5 6.8 0.83 10.2 2.7 2.2 2 0 0 2 2 2 0 CRISPR associated protein Cas6 SlyX PF04102.12 EGG25091.1 - 3.6 8.3 11.6 0.63 10.7 0.7 3.8 3 1 0 3 3 3 0 SlyX Nuc_N PF14448.6 EGG25091.1 - 6.8 6.6 7.0 0.45 10.4 1.0 2.2 3 0 0 3 3 2 0 Nuclease N terminal APG6_N PF17675.1 EGG25091.1 - 9 6.8 22.9 1.7 9.2 0.4 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region tRNA-synt_His PF13393.6 EGG25092.1 - 1.4e-38 132.9 0.0 2e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 EGG25092.1 - 3.4e-18 66.2 0.3 2.1e-17 63.7 0.3 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 EGG25092.1 - 0.00097 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) HGTP_anticodon PF03129.20 EGG25092.1 - 0.0018 18.4 0.1 0.0034 17.5 0.1 1.4 1 0 0 1 1 1 1 Anticodon binding domain ICAT PF06384.11 EGG25092.1 - 0.08 13.2 1.4 0.19 12.0 0.2 2.3 2 1 1 3 3 3 0 Beta-catenin-interacting protein ICAT FA_desaturase PF00487.24 EGG25093.1 - 1.7e-32 113.3 17.1 2.6e-32 112.7 17.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGG25093.1 - 8.3e-25 86.7 0.2 3.2e-24 84.9 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.6 EGG25093.1 - 0.0029 17.7 0.3 0.019 15.1 0.2 2.2 2 0 0 2 2 2 1 Cleavage inducing molecular chaperone PgpA PF04608.13 EGG25093.1 - 0.24 11.4 3.2 0.37 10.8 0.2 2.2 2 0 0 2 2 2 0 Phosphatidylglycerophosphatase A DUF4750 PF15938.5 EGG25093.1 - 5 6.9 6.7 0.26 11.0 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4750) UNC-50 PF05216.13 EGG25094.1 - 1.6e-41 142.3 17.1 3.3e-39 134.7 9.3 2.1 2 0 0 2 2 2 2 UNC-50 family SLD3 PF08639.10 EGG25094.1 - 0.0003 19.7 1.7 0.0004 19.3 1.7 1.1 1 0 0 1 1 1 1 DNA replication regulator SLD3 Folate_carrier PF01770.18 EGG25094.1 - 0.0028 16.5 0.1 0.004 15.9 0.1 1.3 1 0 0 1 1 1 1 Reduced folate carrier DUF913 PF06025.12 EGG25094.1 - 0.0071 15.4 0.0 0.008 15.2 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) BSMAP PF12280.8 EGG25094.1 - 0.014 15.6 0.7 0.024 14.9 0.7 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein TRAP_alpha PF03896.16 EGG25094.1 - 0.024 13.8 0.1 0.034 13.3 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DcuC PF03606.15 EGG25094.1 - 0.026 13.0 2.3 0.91 7.9 0.1 2.0 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier Nucleoside_tran PF01733.18 EGG25094.1 - 0.031 13.7 0.7 0.052 12.9 0.6 1.4 1 1 0 1 1 1 0 Nucleoside transporter Trypan_PARP PF05887.11 EGG25094.1 - 0.039 13.9 0.2 0.071 13.1 0.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AIF_C PF14721.6 EGG25094.1 - 0.057 13.8 0.3 0.12 12.8 0.3 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ydc2-catalyt PF09159.10 EGG25094.1 - 0.059 13.1 2.5 0.085 12.6 2.5 1.2 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Connexin PF00029.19 EGG25094.1 - 0.065 13.0 4.7 0.12 12.2 4.7 1.5 1 1 0 1 1 1 0 Connexin Peptidase_S49_N PF08496.10 EGG25094.1 - 0.082 13.0 3.8 0.14 12.2 3.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HemX PF04375.14 EGG25094.1 - 0.1 11.9 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3915 PF13054.6 EGG25094.1 - 0.11 12.5 8.6 0.43 10.6 8.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) FHIPEP PF00771.20 EGG25094.1 - 0.12 10.8 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family FtsX PF02687.21 EGG25094.1 - 0.13 12.8 3.8 0.15 12.5 0.1 2.3 1 1 0 2 2 2 0 FtsX-like permease family DUF4834 PF16118.5 EGG25094.1 - 0.14 13.1 4.4 0.29 12.1 3.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) MAP17 PF15807.5 EGG25094.1 - 0.21 11.8 3.6 0.39 11.0 3.6 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4337 PF14235.6 EGG25094.1 - 0.28 11.3 6.6 1 9.4 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF2371 PF10177.9 EGG25094.1 - 1.2 9.3 4.5 6 7.0 4.5 2.0 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) MMtag PF10159.9 EGG25094.1 - 2.5 8.4 12.2 5.4 7.4 12.2 1.5 1 0 0 1 1 1 0 Multiple myeloma tumor-associated Atrophin-1 PF03154.15 EGG25094.1 - 2.7 6.2 16.8 3.4 5.8 16.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family Cytomega_UL84 PF06284.11 EGG25094.1 - 4.8 5.5 8.2 6.9 5.0 8.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein ATG_C PF09333.11 EGG25097.1 - 2e-31 108.2 0.5 2e-31 108.2 0.5 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EGG25097.1 - 3e-12 46.7 0.0 3e-12 46.7 0.0 4.0 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 EGG25097.1 - 9.4e-08 31.9 0.2 9.4e-08 31.9 0.2 5.3 6 0 0 6 6 6 1 Autophagy-related protein 2 CAD motif Ank_5 PF13857.6 EGG25098.1 - 0.0017 18.6 0.1 2.2 8.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGG25098.1 - 0.011 16.3 0.8 0.5 11.0 0.1 3.6 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG25098.1 - 0.011 16.1 0.3 18 6.3 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 EGG25098.1 - 0.022 15.3 0.3 0.21 12.2 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) DUF3447 PF11929.8 EGG25098.1 - 0.085 12.8 10.0 0.94 9.5 0.0 4.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3447) Metallophos PF00149.28 EGG25099.1 - 9.2e-13 49.2 0.4 1.9e-12 48.1 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGG25099.1 - 0.0004 20.6 0.0 0.35 11.1 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Dicty_CTDC PF00526.18 EGG25099.1 - 0.0018 18.1 6.3 0.0018 18.1 6.3 5.6 5 1 1 6 6 6 2 Dictyostelium (slime mold) repeat Vta1 PF04652.16 EGG25100.1 - 1.9e-40 138.2 0.0 1.9e-40 138.2 0.0 2.0 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EGG25100.1 - 5.2e-09 35.7 1.1 6.8e-09 35.3 0.1 1.8 2 0 0 2 2 2 1 Vta1 C-terminal domain Ras PF00071.22 EGG25101.1 - 5.5e-21 74.9 5.3 7e-19 68.0 0.3 3.1 2 1 0 2 2 2 1 Ras family EF_assoc_2 PF08356.12 EGG25101.1 - 9.3e-20 70.4 0.1 3.4e-19 68.6 0.0 2.1 2 0 0 2 2 1 1 EF hand associated Roc PF08477.13 EGG25101.1 - 2e-12 47.4 3.2 2.1e-09 37.7 0.0 3.6 5 1 0 5 5 2 2 Ras of Complex, Roc, domain of DAPkinase EF_assoc_1 PF08355.12 EGG25101.1 - 2.5e-11 43.0 0.8 8.8e-11 41.3 0.8 1.9 1 0 0 1 1 1 1 EF hand associated EF-hand_7 PF13499.6 EGG25101.1 - 6.2e-09 36.2 1.3 0.0071 16.8 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair TniB PF05621.11 EGG25101.1 - 1.8e-08 34.1 0.3 0.0013 18.2 0.1 3.5 3 1 0 3 3 3 2 Bacterial TniB protein EF-hand_6 PF13405.6 EGG25101.1 - 3.8e-08 32.6 0.9 0.015 15.2 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGG25101.1 - 9e-08 31.1 0.7 0.0078 15.7 0.1 2.8 2 0 0 2 2 2 2 EF hand AAA_24 PF13479.6 EGG25101.1 - 4.5e-07 29.8 2.0 0.0057 16.4 0.9 3.5 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EGG25101.1 - 2.7e-06 27.5 0.0 0.037 13.9 0.0 3.0 3 0 0 3 3 2 2 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGG25101.1 - 5.5e-06 26.7 0.1 0.19 12.0 0.0 3.4 3 1 0 3 3 3 2 AAA domain Arf PF00025.21 EGG25101.1 - 5.8e-06 25.9 1.4 0.0011 18.5 0.3 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family EF-hand_5 PF13202.6 EGG25101.1 - 8.4e-06 25.1 2.0 0.018 14.5 0.2 2.6 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 EGG25101.1 - 8.8e-06 25.8 0.4 0.048 13.8 0.1 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase Septin PF00735.18 EGG25101.1 - 1.3e-05 24.6 0.9 0.02 14.2 0.1 3.0 2 1 1 3 3 3 2 Septin AAA_14 PF13173.6 EGG25101.1 - 1.5e-05 25.1 0.1 0.068 13.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGG25101.1 - 3.5e-05 24.2 0.0 0.37 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGG25101.1 - 8.5e-05 22.2 0.3 0.32 10.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran PF00005.27 EGG25101.1 - 0.00018 22.0 0.0 0.2 12.1 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 EGG25101.1 - 0.00026 20.6 0.3 0.054 13.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region EF-hand_10 PF14788.6 EGG25101.1 - 0.00027 20.7 2.0 0.023 14.6 0.1 3.1 3 0 0 3 3 2 1 EF hand AAA_32 PF13654.6 EGG25101.1 - 0.00063 18.7 0.2 0.023 13.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGG25101.1 - 0.00069 20.0 0.2 4 7.9 0.0 3.5 3 1 0 3 3 3 1 RNA helicase EF-hand_8 PF13833.6 EGG25101.1 - 0.0007 19.4 0.4 0.95 9.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair AAA_28 PF13521.6 EGG25101.1 - 0.0013 19.0 0.0 0.11 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGG25101.1 - 0.0016 19.0 0.1 0.029 14.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 EGG25101.1 - 0.0033 17.6 0.0 3 8.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EGG25101.1 - 0.0041 17.1 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 EGG25101.1 - 0.0043 17.0 3.4 0.65 9.9 0.0 3.6 4 0 0 4 4 3 1 RsgA GTPase MCM PF00493.23 EGG25101.1 - 0.0051 15.9 0.1 0.26 10.3 0.0 2.6 2 0 0 2 2 2 1 MCM P-loop domain DAP3 PF10236.9 EGG25101.1 - 0.0061 15.8 0.0 0.82 8.8 0.0 2.6 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 ATP_bind_1 PF03029.17 EGG25101.1 - 0.011 15.6 2.6 4.4 7.0 0.1 3.2 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 EGG25101.1 - 0.013 14.7 0.2 0.71 9.0 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain GTP_EFTU PF00009.27 EGG25101.1 - 0.013 15.1 1.1 10 5.6 0.0 3.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 EGG25101.1 - 0.013 14.8 0.1 0.58 9.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 EGG25101.1 - 0.023 14.3 1.0 0.96 9.0 0.5 2.7 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 EGG25101.1 - 0.042 13.5 0.1 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 EGG25101.1 - 0.075 12.3 0.0 5.9 6.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 EGG25101.1 - 0.087 12.7 0.7 2 8.3 0.1 2.9 3 0 0 3 3 2 0 NTPase MobB PF03205.14 EGG25101.1 - 0.12 12.3 0.1 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 EGG25101.1 - 0.13 11.8 0.0 1.5 8.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGG25101.1 - 0.24 11.4 0.0 0.24 11.4 0.0 3.1 3 1 0 3 3 2 0 Dynamin family P5-ATPase PF12409.8 EGG25101.1 - 0.28 11.3 0.1 0.28 11.3 0.1 2.2 2 1 0 2 2 2 0 P5-type ATPase cation transporter AAA_23 PF13476.6 EGG25101.1 - 2.7 8.4 12.5 2.8 8.4 0.2 3.7 3 1 0 3 3 3 0 AAA domain Peptidase_C13 PF01650.18 EGG25103.1 - 4.8e-47 160.6 0.0 6.4e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 EGG25103.1 - 0.013 15.8 0.2 0.037 14.3 0.0 1.9 2 0 0 2 2 2 0 Mid domain of argonaute Dynein_light PF01221.18 EGG25103.1 - 0.042 14.2 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 Dynein light chain type 1 V-SNARE PF05008.15 EGG25104.1 - 0.00013 22.3 1.3 0.00013 22.3 1.3 2.1 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus TPR_MLP1_2 PF07926.12 EGG25104.1 - 0.0025 17.9 0.4 0.0041 17.2 0.4 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 EGG25104.1 - 0.054 13.7 4.0 0.047 13.9 2.1 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LRRC37AB_C PF14914.6 EGG25104.1 - 0.088 12.7 2.0 0.13 12.2 1.7 1.5 1 1 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF4840 PF16128.5 EGG25104.1 - 0.22 11.5 5.3 1.5 8.9 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4840) DUF4200 PF13863.6 EGG25104.1 - 7.2 7.0 9.4 2.1 8.8 0.6 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) FAD_binding_3 PF01494.19 EGG25105.1 - 2.2e-17 63.3 0.0 3.3e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGG25105.1 - 2.5e-06 27.3 0.0 0.00058 19.6 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGG25105.1 - 0.00012 22.3 0.0 0.00031 20.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGG25105.1 - 0.012 14.9 0.1 1.6 7.9 0.0 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGG25105.1 - 0.091 12.0 0.0 10 5.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 EGG25106.1 - 2.9e-72 243.2 0.0 6.4e-72 242.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG25106.1 - 1e-46 159.3 0.0 1.9e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG25106.1 - 4.7e-06 26.1 0.3 3.6e-05 23.2 0.0 2.3 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 EGG25106.1 - 0.00018 21.5 0.0 0.03 14.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGG25106.1 - 0.001 17.9 0.1 0.0025 16.7 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase ILVD_EDD PF00920.21 EGG25106.1 - 0.078 11.6 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Dehydratase family Gcd10p PF04189.13 EGG25106.1 - 0.14 11.2 5.2 0.27 10.3 5.2 1.4 1 0 0 1 1 1 0 Gcd10p family FAD_binding_1 PF00667.20 EGG25107.1 - 5.3e-33 114.5 0.0 9.5e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EGG25107.1 - 2.2e-19 70.1 0.0 4.9e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGG25107.1 - 0.19 11.8 4.7 0.2 11.8 0.0 3.2 3 1 0 3 3 3 0 Ferric reductase NAD binding domain DUF2034 PF10356.9 EGG25108.1 - 2.4e-21 76.0 2.1 1.5e-11 44.1 0.1 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EGG25108.1 - 1.5e-11 44.3 0.0 3.1e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease Pkinase PF00069.25 EGG25109.1 - 7.1e-45 153.4 2.5 2.2e-35 122.3 0.0 3.0 2 2 1 3 3 3 2 Protein kinase domain RhoGAP PF00620.27 EGG25109.1 - 9.9e-30 103.4 0.3 9.9e-30 103.4 0.3 2.1 2 0 0 2 2 2 1 RhoGAP domain Pkinase_Tyr PF07714.17 EGG25109.1 - 1.4e-29 103.2 0.0 4.7e-24 85.1 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGG25109.1 - 0.004 16.5 0.0 0.015 14.6 0.0 2.0 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 EGG25109.1 - 0.059 13.9 1.2 0.74 10.4 0.2 2.6 2 0 0 2 2 2 0 PH domain Proteasome PF00227.26 EGG25110.1 - 4.1e-49 166.7 0.7 4.8e-49 166.4 0.7 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EGG25110.1 - 0.00015 21.1 0.4 0.00015 21.1 0.4 2.1 2 0 0 2 2 2 1 Proteasome beta subunits C terminal SURF2 PF05477.11 EGG25111.1 - 1.7e-25 90.1 42.2 8.8e-25 87.8 42.2 2.1 1 1 0 1 1 1 1 Surfeit locus protein 2 (SURF2) BUD22 PF09073.10 EGG25111.1 - 0.0015 17.9 62.8 0.0031 16.9 62.8 1.6 1 1 0 1 1 1 1 BUD22 Mpp10 PF04006.12 EGG25111.1 - 0.52 8.7 66.9 0.65 8.4 66.9 1.1 1 0 0 1 1 1 0 Mpp10 protein Pro_isomerase PF00160.21 EGG25112.1 - 7.9e-43 146.5 0.1 2.1e-42 145.1 0.1 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EGG25112.1 - 3.8e-16 58.7 0.0 8.7e-16 57.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1428 PF07237.11 EGG25112.1 - 0.29 11.4 2.2 0.8 10.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1428) Shisa PF13908.6 EGG25114.1 - 0.0076 16.5 0.2 0.015 15.6 0.2 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator OapA_N PF08525.11 EGG25114.1 - 0.0077 16.2 0.7 0.0077 16.2 0.7 1.8 2 0 0 2 2 2 1 Opacity-associated protein A N-terminal motif TLP-20 PF06088.11 EGG25114.1 - 0.039 13.8 6.1 0.064 13.1 6.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Zip PF02535.22 EGG25114.1 - 0.098 11.9 0.8 0.15 11.2 0.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 EGG25114.1 - 0.35 9.2 10.7 0.044 12.2 0.8 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 EGG25114.1 - 9.3 4.9 13.8 0.068 11.9 4.9 1.9 2 0 0 2 2 2 0 Presenilin adh_short PF00106.25 EGG25115.1 - 1.8e-40 138.5 1.3 2.1e-40 138.3 1.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG25115.1 - 5.3e-39 134.2 0.2 7e-39 133.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGG25115.1 - 4.8e-13 49.4 0.8 9e-13 48.5 0.8 1.4 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EGG25115.1 - 4.8e-05 22.5 0.5 0.0006 18.9 0.4 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGG25115.1 - 7.1e-05 22.4 0.2 0.00017 21.1 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGG25115.1 - 0.059 12.5 0.1 0.14 11.3 0.1 1.7 1 1 0 1 1 1 0 Male sterility protein ZNRF_3_ecto PF18212.1 EGG25115.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.6 1 1 0 1 1 1 0 ZNRF-3 Ectodomain MpPF26 PF07666.11 EGG25116.1 - 0.012 15.7 7.9 0.016 15.3 7.8 1.3 1 1 0 1 1 1 0 M penetrans paralogue family 26 Tmemb_9 PF05434.11 EGG25116.1 - 0.074 12.9 1.0 0.1 12.5 1.0 1.2 1 0 0 1 1 1 0 TMEM9 PRIMA1 PF16101.5 EGG25116.1 - 0.18 11.8 0.5 0.22 11.6 0.4 1.3 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 GATA PF00320.27 EGG25117.1 - 4.1e-16 58.3 3.6 9e-16 57.2 3.6 1.6 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.7 EGG25117.1 - 0.058 13.4 0.6 0.12 12.4 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 EGG25117.1 - 0.17 12.2 0.4 0.34 11.2 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbon Zn-ribbon_8 PF09723.10 EGG25117.1 - 0.18 12.0 0.6 0.34 11.1 0.6 1.4 1 0 0 1 1 1 0 Zinc ribbon domain CRAL_TRIO PF00650.20 EGG25118.1 - 2.2e-34 118.5 0.0 3.4e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGG25118.1 - 1.3e-08 34.9 0.2 3.1e-08 33.7 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ESP PF16590.5 EGG25120.1 - 0.046 14.0 1.6 0.046 14.0 1.6 1.8 1 1 1 2 2 2 0 Exocrine gland-secreting peptide TFIIF_alpha PF05793.12 EGG25121.1 - 4.2e-29 101.6 38.3 4.2e-29 101.6 38.3 2.3 1 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BLOC1S3 PF15753.5 EGG25122.1 - 9.2e-06 25.9 20.0 4.4e-05 23.7 3.3 2.3 1 1 0 2 2 2 2 Biogenesis of lysosome-related organelles complex 1 subunit 3 RCDG1 PF15725.5 EGG25122.1 - 0.016 15.6 1.4 0.03 14.7 1.4 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein PTPRCAP PF15713.5 EGG25122.1 - 0.54 10.5 11.1 0.85 9.9 11.1 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated GP67 PF17634.2 EGG25122.1 - 1.1 9.8 12.8 1.8 9.0 12.8 1.3 1 0 0 1 1 1 0 Gene product 67 YtxH PF12732.7 EGG25123.1 - 0.0055 17.2 2.4 0.019 15.5 2.1 1.9 1 1 1 2 2 2 2 YtxH-like protein HNF-1_N PF04814.13 EGG25123.1 - 0.13 12.9 2.2 0.16 12.6 2.2 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Dicty_REP PF05086.12 EGG25123.1 - 0.28 9.1 5.3 0.27 9.2 5.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Amidohydro_3 PF07969.11 EGG25124.1 - 4e-16 59.5 0.5 1.1e-06 28.4 0.0 2.9 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGG25124.1 - 3.5e-14 52.9 0.2 1.1e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family GDP_Man_Dehyd PF16363.5 EGG25125.1 - 4.3e-150 499.7 0.0 4.9e-150 499.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGG25125.1 - 2.7e-75 252.9 0.0 3.4e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGG25125.1 - 0.00026 20.2 0.0 0.00044 19.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EGG25125.1 - 0.0014 18.2 0.0 0.0031 17.1 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EGG25125.1 - 0.0072 15.5 0.0 0.015 14.4 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF562 PF04763.12 EGG25125.1 - 0.098 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF562) PMI_typeI PF01238.21 EGG25126.1 - 3e-100 336.0 0.0 4.6e-100 335.4 0.0 1.3 1 0 0 1 1 1 1 Phosphomannose isomerase type I ADH_zinc_N PF00107.26 EGG25126.1 - 1.5e-08 34.7 0.1 4.4e-08 33.2 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Cupin_2 PF07883.11 EGG25126.1 - 0.0026 17.4 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 1 Cupin domain DapB_N PF01113.20 EGG25126.1 - 0.032 14.4 0.1 0.072 13.2 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 EGG25126.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding TMEM234 PF10639.9 EGG25127.1 - 5.1e-42 142.6 3.9 6.6e-42 142.2 3.9 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 EGG25127.1 - 7.6e-05 22.9 8.8 0.0015 18.7 6.8 2.3 2 1 0 2 2 2 1 EamA-like transporter family PNTB PF02233.16 EGG25127.1 - 0.0038 16.2 2.6 0.0045 16.0 2.6 1.2 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit Acatn PF13000.7 EGG25128.1 - 2.9e-130 435.4 22.7 2e-103 346.8 10.8 2.1 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Activator_LAG-3 PF11498.8 EGG25128.1 - 0.008 15.2 0.3 0.011 14.7 0.3 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 adh_short PF00106.25 EGG25129.1 - 2.2e-45 154.5 0.0 3e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGG25129.1 - 1.7e-37 129.3 0.0 2.4e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EGG25129.1 - 6.7e-07 29.0 0.1 1.4e-06 28.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EGG25129.1 - 2.2e-05 24.4 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EGG25129.1 - 7.4e-05 22.4 0.4 0.00012 21.7 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EGG25129.1 - 0.00094 18.7 0.1 0.0015 18.0 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGG25129.1 - 0.0011 18.2 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGG25129.1 - 0.0034 17.3 0.1 0.0058 16.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding UFC1 PF08694.11 EGG25129.1 - 0.04 13.5 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 DUF1776 PF08643.10 EGG25129.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_4 PF07993.12 EGG25129.1 - 0.39 9.8 1.3 0.76 8.9 1.2 1.7 1 1 0 1 1 1 0 Male sterility protein DUF3430 PF11912.8 EGG25130.1 - 5.5e-19 69.1 10.2 7.1e-19 68.7 10.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) PP2C PF00481.21 EGG25133.1 - 7.5e-11 42.2 0.0 8.8e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Mito_carr PF00153.27 EGG25134.1 - 1.9e-63 210.4 6.1 3.2e-23 81.5 0.1 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein PP2C PF00481.21 EGG25134.1 - 6.4e-37 127.6 0.1 1.5e-36 126.4 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C NAPRTase_C PF17956.1 EGG25135.1 - 0.012 16.1 0.9 0.042 14.3 1.2 1.8 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain Acyltransferase PF01553.21 EGG25136.1 - 2.5e-23 82.2 0.0 3.6e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase RRM_1 PF00076.22 EGG25137.1 - 2.9e-14 52.6 0.1 5e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGG25137.1 - 7.8e-08 32.1 2.8 2.6e-07 30.4 2.8 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGG25137.1 - 0.00069 19.5 2.5 0.0014 18.6 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGG25137.1 - 0.0015 18.3 2.1 0.0025 17.6 2.1 1.3 1 0 0 1 1 1 1 Zinc knuckle RRM_3 PF08777.11 EGG25137.1 - 0.014 15.4 0.1 0.014 15.4 0.1 2.1 2 0 0 2 2 2 0 RNA binding motif DUF4322 PF14210.6 EGG25137.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) GGDEF PF00990.21 EGG25138.1 - 8.3e-30 103.7 0.1 1.6e-29 102.8 0.1 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Guanylate_cyc PF00211.20 EGG25138.1 - 0.0032 17.1 0.1 0.0059 16.2 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain zf-UBR PF02207.20 EGG25140.1 - 5.8e-20 71.2 14.7 5.8e-20 71.2 14.7 3.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EGG25140.1 - 2e-10 40.3 0.0 5.8e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 EGG25140.1 - 0.012 16.0 1.5 0.012 16.0 1.5 4.5 4 1 0 4 4 4 0 Ring finger domain DUF1117 PF06547.12 EGG25140.1 - 3.6 8.2 7.5 15 6.1 0.1 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1117) DUF1726 PF08351.11 EGG25141.1 - 1.7e-15 56.7 0.1 3.5e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Smr PF01713.21 EGG25141.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Smr domain GNAT_acetyltr_2 PF13718.6 EGG25143.1 - 3.2e-74 249.2 0.0 3.2e-74 249.2 0.0 2.9 3 0 0 3 3 3 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EGG25143.1 - 3.5e-67 226.6 18.9 3.5e-67 226.6 18.9 2.7 3 0 0 3 3 3 1 Possible tRNA binding domain Acetyltransf_1 PF00583.25 EGG25143.1 - 0.00078 19.7 0.0 0.0099 16.1 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG25143.1 - 0.022 15.2 0.0 0.056 13.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BUD22 PF09073.10 EGG25143.1 - 2.8 7.2 35.9 2.1 7.6 1.2 2.1 2 0 0 2 2 2 0 BUD22 Acyl-CoA_dh_1 PF00441.24 EGG25144.1 - 8e-30 104.0 0.5 1.4e-29 103.3 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGG25144.1 - 1.8e-23 82.5 0.0 3.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGG25144.1 - 4.9e-18 65.8 0.0 8.9e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGG25144.1 - 1.3e-06 28.7 0.0 2.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 EGG25145.1 - 5.9e-70 235.6 0.2 1.5e-69 234.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG25145.1 - 3.9e-50 170.6 0.0 8.6e-50 169.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG25145.1 - 4e-06 25.9 0.0 4e-06 25.9 0.0 2.5 2 1 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 EGG25145.1 - 0.0072 16.5 0.0 0.026 14.7 0.0 2.0 2 0 0 2 2 2 1 ABC1 family Kinase-like PF14531.6 EGG25145.1 - 0.12 11.7 0.1 0.7 9.2 0.0 2.2 2 1 0 2 2 2 0 Kinase-like Pkinase PF00069.25 EGG25146.1 - 1.4e-68 231.1 0.1 1.4e-68 231.1 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG25146.1 - 7.1e-35 120.5 0.0 2.1e-34 119.0 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EGG25146.1 - 5.8e-23 80.9 12.5 4.6e-14 52.4 0.1 4.0 3 1 0 3 3 3 2 POLO box duplicated region Phage_H_T_join PF05521.11 EGG25146.1 - 0.11 13.0 7.8 1.2 9.7 2.9 3.3 3 0 0 3 3 3 0 Phage head-tail joining protein Lactamase_B_2 PF12706.7 EGG25147.1 - 2.2e-30 105.7 0.1 3.3e-30 105.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGG25147.1 - 8.3e-11 42.0 0.2 1.5e-10 41.2 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Cytochrom_C PF00034.21 EGG25148.1 - 5.5e-11 43.5 0.1 7.5e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGG25148.1 - 4.3e-07 30.1 1.1 1.5e-06 28.4 1.1 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EGG25148.1 - 2.4e-05 24.1 0.1 0.00088 19.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome c-550 domain AAA_16 PF13191.6 EGG25149.1 - 0.002 18.5 0.0 0.24 11.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EGG25149.1 - 0.005 17.2 0.1 0.6 10.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.27 EGG25149.1 - 0.014 15.9 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter SMC_N PF02463.19 EGG25149.1 - 0.015 14.7 0.1 0.035 13.5 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EGG25149.1 - 0.016 15.7 0.0 0.039 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGG25149.1 - 0.044 13.9 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 EGG25149.1 - 0.08 13.4 0.0 0.28 11.6 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TRIF-NTD PF17798.1 EGG25149.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 TRIF N-terminal domain Mg_chelatase PF01078.21 EGG25149.1 - 0.13 11.6 0.1 0.43 9.9 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EGG25149.1 - 0.14 11.9 0.2 0.85 9.4 0.1 2.2 1 1 1 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGG25149.1 - 0.14 12.6 1.3 0.3 11.5 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGG25149.1 - 0.18 12.1 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain TRAPPC-Trs85 PF12739.7 EGG25150.1 - 1.1e-58 199.2 0.8 1.6e-53 182.1 0.2 2.5 1 1 1 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Transglut_C PF00927.22 EGG25150.1 - 0.0045 17.1 0.2 9.1 6.5 0.0 3.9 2 1 1 3 3 3 1 Transglutaminase family, C-terminal ig like domain TPR_7 PF13176.6 EGG25150.1 - 0.016 15.2 0.3 0.21 11.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGG25150.1 - 0.026 14.8 0.4 0.12 12.7 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF974 PF06159.13 EGG25150.1 - 0.039 13.7 0.0 0.85 9.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF974) TPR_2 PF07719.17 EGG25150.1 - 0.043 13.9 0.1 2.6 8.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC2_membrane_3 PF12698.7 EGG25152.1 - 6.8e-29 101.0 28.7 1.7e-28 99.8 25.6 2.3 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 EGG25152.1 - 2.1e-26 93.1 0.0 4.1e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Pmp3 PF01679.17 EGG25152.1 - 3e-10 40.1 2.0 3e-10 40.1 2.0 2.4 2 1 0 2 2 1 1 Proteolipid membrane potential modulator AAA_21 PF13304.6 EGG25152.1 - 4.4e-08 33.3 0.0 0.0011 18.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 EGG25152.1 - 8.9e-06 25.3 22.8 8.9e-06 25.3 22.8 2.4 2 0 0 2 2 2 1 ABC-2 type transporter SMC_N PF02463.19 EGG25152.1 - 0.00052 19.5 0.1 0.39 10.1 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EGG25152.1 - 0.0017 18.3 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_23 PF13476.6 EGG25152.1 - 0.0021 18.6 0.0 0.0054 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 EGG25152.1 - 0.016 14.8 0.1 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGG25152.1 - 0.074 12.8 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC2_membrane_2 PF12679.7 EGG25152.1 - 0.26 10.5 16.5 0.3 10.3 13.8 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4162 PF13732.6 EGG25152.1 - 0.39 11.5 2.8 0.24 12.2 0.4 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4162) DUF4956 PF16316.5 EGG25152.1 - 1.6 8.4 7.8 3.6 7.2 7.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) DUF308 PF03729.13 EGG25153.1 - 2e-05 24.8 4.8 2e-05 24.8 4.8 2.1 2 0 0 2 2 2 1 Short repeat of unknown function (DUF308) Orf78 PF06024.12 EGG25153.1 - 0.00043 20.5 7.6 0.22 11.8 0.0 3.0 3 0 0 3 3 3 2 Orf78 (ac78) DUF4400 PF14348.6 EGG25153.1 - 0.0054 16.2 4.0 0.0054 16.2 4.0 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4400) DUF2371 PF10177.9 EGG25153.1 - 0.0077 16.4 0.7 3.3 7.9 0.0 2.9 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2371) DUF2370 PF10176.9 EGG25153.1 - 0.039 13.6 3.4 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Tetraspanin PF00335.20 EGG25153.1 - 0.057 13.1 13.2 1 9.0 13.2 2.1 1 1 0 1 1 1 0 Tetraspanin family Connexin PF00029.19 EGG25153.1 - 0.069 12.9 0.0 0.94 9.2 0.0 2.1 2 0 0 2 2 2 0 Connexin DUF4834 PF16118.5 EGG25153.1 - 0.072 14.1 0.1 0.072 14.1 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4834) Neurensin PF14927.6 EGG25153.1 - 0.1 12.3 1.7 0.16 11.7 0.1 2.0 2 1 0 3 3 3 0 Neurensin DUF5493 PF17597.2 EGG25153.1 - 0.13 12.6 4.1 1.9 8.8 1.0 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5493) CSG2 PF16965.5 EGG25153.1 - 0.13 11.2 2.9 0.35 9.8 0.3 2.1 1 1 0 2 2 2 0 Ceramide synthase regulator DUF3899 PF13038.6 EGG25153.1 - 0.16 12.5 0.1 0.16 12.5 0.1 3.2 5 0 0 5 5 2 0 Domain of unknown function (DUF3899) Bac_export_2 PF01312.19 EGG25153.1 - 0.26 10.5 2.1 1.3 8.2 0.3 2.0 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family CrgA PF06781.12 EGG25153.1 - 0.41 10.7 0.0 0.41 10.7 0.0 2.4 2 1 1 3 3 3 0 Cell division protein CrgA Cadherin_C_2 PF16492.5 EGG25153.1 - 0.41 11.4 0.0 0.41 11.4 0.0 2.9 4 0 0 4 4 3 0 Cadherin cytoplasmic C-terminal GPDPase_memb PF10110.9 EGG25153.1 - 0.51 9.1 0.0 0.51 9.1 0.0 2.4 2 1 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Gti1_Pac2 PF09729.9 EGG25153.1 - 1.2 9.2 7.9 1.8 8.6 2.3 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family COPI_assoc PF08507.10 EGG25153.1 - 1.2 9.1 13.4 3.7 7.6 0.0 3.1 2 1 1 3 3 3 0 COPI associated protein Secretin_N_2 PF07655.13 EGG25153.1 - 2.9 8.5 16.8 13 6.4 11.9 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain DUF202 PF02656.15 EGG25153.1 - 4.3 7.8 10.5 4.9 7.7 0.2 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF202) SK_channel PF03530.14 EGG25154.1 - 1.3e-06 28.3 3.2 6.4e-06 26.1 3.2 2.1 1 1 0 1 1 1 1 Calcium-activated SK potassium channel Nbl1_Borealin_N PF10444.9 EGG25154.1 - 0.0075 15.9 3.4 0.07 12.8 1.9 2.4 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal SLATT_5 PF18160.1 EGG25154.1 - 0.11 11.8 2.7 7.6 5.8 0.4 2.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Ion_trans_2 PF07885.16 EGG25154.1 - 0.22 11.5 4.1 0.38 10.7 2.2 2.4 2 1 0 2 2 2 0 Ion channel IQ PF00612.27 EGG25154.1 - 0.23 11.4 1.7 3.2 7.8 0.9 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF4181 PF13789.6 EGG25154.1 - 3.9 7.8 10.0 0.47 10.8 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) FSH1 PF03959.13 EGG25155.1 - 4.2e-50 170.4 0.1 1.3e-49 168.8 0.1 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase_phd PF10503.9 EGG25155.1 - 0.11 11.9 0.0 0.59 9.6 0.0 1.9 1 1 0 1 1 1 0 Esterase PHB depolymerase NCA2 PF08637.10 EGG25156.1 - 5.8e-63 212.8 6.1 5.8e-63 212.8 6.1 2.6 3 0 0 3 3 3 1 ATP synthase regulation protein NCA2 Pox_Ag35 PF03286.14 EGG25156.1 - 4.4e-05 23.4 16.5 0.00018 21.4 8.0 2.6 2 0 0 2 2 2 2 Pox virus Ag35 surface protein Androgen_recep PF02166.16 EGG25156.1 - 1.7 7.4 5.9 4.1 6.1 5.9 1.6 1 0 0 1 1 1 0 Androgen receptor KOG2701 PF09762.9 EGG25157.1 - 1.7e-53 181.5 16.6 2e-53 181.3 0.0 5.0 3 2 1 4 4 4 1 Coiled-coil domain-containing protein (DUF2037) Med10 PF09748.9 EGG25157.1 - 0.0017 18.3 1.0 0.0017 18.3 1.0 3.6 2 2 1 3 3 3 1 Transcription factor subunit Med10 of Mediator complex Mce4_CUP1 PF11887.8 EGG25157.1 - 2.4 7.6 7.9 23 4.3 0.5 3.7 3 2 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative NPV_P10 PF05531.12 EGG25157.1 - 7 7.2 15.1 0.61 10.6 2.0 4.2 2 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Trimer_CC PF08954.11 EGG25157.1 - 7 6.3 9.3 8.4 6.0 6.8 2.5 2 0 0 2 2 2 0 Trimerisation motif COQ9 PF08511.11 EGG25158.1 - 4.5e-29 100.0 0.7 1.1e-28 98.8 0.7 1.7 1 0 0 1 1 1 1 COQ9 SRCR PF00530.18 EGG25158.1 - 0.076 13.5 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain SR-25 PF10500.9 EGG25158.1 - 0.69 9.5 6.4 0.95 9.0 6.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RabGAP-TBC PF00566.18 EGG25160.1 - 1.2e-47 162.3 2.9 1.2e-47 162.3 2.9 3.5 5 0 0 5 5 5 1 Rab-GTPase-TBC domain GRAM PF02893.20 EGG25160.1 - 4.5e-09 36.2 9.7 5.8e-06 26.2 0.4 3.8 2 1 0 2 2 2 2 GRAM domain EF-hand_1 PF00036.32 EGG25160.1 - 0.00087 18.7 1.5 0.00087 18.7 1.5 3.3 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.6 EGG25160.1 - 0.14 12.1 12.6 0.32 11.0 2.9 3.9 2 1 1 3 3 3 0 EF-hand domain Androgen_recep PF02166.16 EGG25160.1 - 1.9 7.2 16.6 0.22 10.3 6.2 2.9 4 0 0 4 4 4 0 Androgen receptor EF-hand_7 PF13499.6 EGG25160.1 - 8.9 6.8 11.9 0.42 11.1 1.2 3.5 2 1 1 3 3 3 0 EF-hand domain pair HATPase_c_3 PF13589.6 EGG25161.1 - 1.7e-19 70.0 0.5 4.5e-19 68.6 0.5 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SMC_hinge PF06470.13 EGG25161.1 - 2e-08 34.5 0.0 4.7e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain HATPase_c PF02518.26 EGG25161.1 - 3.6e-07 30.7 0.2 1.5e-06 28.7 0.2 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ISPD_C PF18706.1 EGG25162.1 - 0.0062 16.2 3.5 0.0093 15.6 3.5 1.2 1 0 0 1 1 1 1 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Ank_2 PF12796.7 EGG25163.1 - 1e-07 32.4 0.7 0.23 12.1 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGG25163.1 - 0.0024 18.2 0.2 30 5.6 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat DUF5376 PF17346.2 EGG25163.1 - 2.5 8.5 13.1 4.1 7.8 0.2 4.5 3 1 0 4 4 4 0 Family of unknown function (DUF5376) ADH_zinc_N PF00107.26 EGG25164.1 - 2.4e-20 72.8 0.0 5.6e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGG25164.1 - 5.6e-09 37.2 0.0 2.8e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGG25164.1 - 5.7e-08 32.6 0.2 4.9e-07 29.6 0.1 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 EGG25164.1 - 2.3e-05 24.0 0.6 3.4e-05 23.4 0.6 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CENP-T_C PF15511.6 EGG25164.1 - 0.0081 16.3 0.0 0.036 14.2 0.0 2.0 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGG25164.1 - 0.015 15.7 0.1 0.043 14.2 0.1 1.7 1 0 0 1 1 1 0 CENP-S protein TusA PF01206.17 EGG25164.1 - 0.1 12.5 0.1 0.88 9.5 0.0 2.4 1 1 2 3 3 3 0 Sulfurtransferase TusA CENP-T_C PF15511.6 EGG25166.1 - 2.4e-08 34.0 0.0 3.3e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EGG25166.1 - 2.2e-05 24.5 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Ribosomal_L27A PF00828.19 EGG25166.1 - 0.00018 22.2 0.4 0.0002 22.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A CBFD_NFYB_HMF PF00808.23 EGG25166.1 - 0.00024 21.3 0.0 0.00046 20.4 0.0 1.5 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EGG25166.1 - 0.00037 20.8 0.2 0.00048 20.4 0.2 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EGG25166.1 - 0.0024 17.9 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EGG25166.1 - 0.0027 18.1 0.2 0.0033 17.8 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EGG25166.1 - 0.012 15.7 0.1 0.019 15.0 0.0 1.4 1 1 1 2 2 2 0 Bromodomain associated TFIID-18kDa PF02269.16 EGG25166.1 - 0.11 12.6 0.3 0.32 11.0 0.1 1.7 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit Ras PF00071.22 EGG25168.1 - 5.4e-60 201.7 0.5 6.5e-60 201.4 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG25168.1 - 1.3e-34 118.9 0.1 2.6e-34 118.0 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG25168.1 - 7.1e-14 51.6 0.1 9.3e-14 51.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGG25168.1 - 2.8e-06 27.4 0.1 3.9e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGG25168.1 - 3.5e-05 23.8 0.1 0.075 12.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGG25168.1 - 8.9e-05 22.0 0.2 0.00013 21.4 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGG25168.1 - 0.0046 17.4 0.0 0.0067 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EGG25168.1 - 0.009 15.8 0.1 0.025 14.3 0.1 1.7 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EGG25168.1 - 0.01 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.12 EGG25168.1 - 0.019 14.3 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.18 EGG25168.1 - 0.056 12.7 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Septin Hexokinase_2 PF03727.16 EGG25168.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 Hexokinase AAA_22 PF13401.6 EGG25168.1 - 0.066 13.5 0.1 0.44 10.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EGG25168.1 - 0.11 12.1 0.3 0.38 10.3 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B ATPase_2 PF01637.18 EGG25168.1 - 0.12 12.3 0.8 1.2 9.0 0.8 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EGG25168.1 - 0.14 12.2 0.7 2.2 8.3 0.2 2.5 1 1 1 2 2 2 0 AAA domain YtzH PF14165.6 EGG25168.1 - 0.18 12.3 0.2 0.45 11.0 0.0 1.7 2 0 0 2 2 2 0 YtzH-like protein Rad21_Rec8_N PF04825.13 EGG25169.1 - 4.2e-17 62.3 0.1 1e-16 61.0 0.1 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGG25169.1 - 1.8e-11 43.1 0.0 3.8e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 EGG25169.1 - 9.2e-05 22.5 1.3 0.00075 19.5 0.0 2.8 3 1 1 4 4 4 1 Segregation and condensation protein ScpA Borrelia_orfA PF02414.15 EGG25170.1 - 0.026 14.2 0.5 0.042 13.5 0.0 1.5 2 0 0 2 2 2 0 Borrelia ORF-A ANAPC2 PF08672.11 EGG25170.1 - 0.25 11.9 2.2 0.37 11.3 0.6 2.1 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 UCH PF00443.29 EGG25171.1 - 9.7e-54 182.5 0.0 3.5e-45 154.5 2.8 5.4 5 2 0 5 5 5 3 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGG25171.1 - 3.6e-31 109.0 5.0 3.6e-31 109.0 5.0 4.3 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGG25171.1 - 2.1e-05 24.2 1.6 2.6e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family DUF2489 PF10675.9 EGG25171.1 - 0.11 12.5 3.2 0.57 10.1 2.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) MitMem_reg PF13012.6 EGG25171.1 - 4.2 7.8 13.4 0.091 13.2 0.3 4.5 4 1 0 4 4 4 0 Maintenance of mitochondrial structure and function VPS9 PF02204.18 EGG25173.1 - 2.6e-20 72.6 0.9 5.3e-20 71.6 0.1 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF726 PF05277.12 EGG25173.1 - 1.6e-11 43.8 1.0 3e-11 42.9 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF726 PF05277.12 EGG25174.1 - 5.5e-46 157.1 0.4 1.5e-39 135.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF726) DUF900 PF05990.12 EGG25174.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3089 PF11288.8 EGG25174.1 - 0.098 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_1 PF00561.20 EGG25174.1 - 0.13 11.9 0.0 0.53 9.9 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGG25174.1 - 0.21 12.2 0.0 0.29 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family RNA_pol_3_Rpc31 PF11705.8 EGG25175.1 - 1.4e-05 25.5 25.8 8.9e-05 22.8 25.8 2.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Voldacs PF03517.13 EGG25175.1 - 0.035 14.2 6.3 0.03 14.5 1.1 2.2 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Nucleo_P87 PF07267.11 EGG25175.1 - 1.3 7.8 7.4 1.6 7.5 7.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FYDLN_acid PF09538.10 EGG25175.1 - 2 9.2 14.2 0.12 13.0 5.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CNDH2_C PF16858.5 EGG25175.1 - 4.5 7.1 10.3 0.74 9.6 6.8 1.4 1 1 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4525 PF15027.6 EGG25176.1 - 0.55 10.0 5.8 1 9.1 5.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4525) Ank_2 PF12796.7 EGG25177.1 - 1.7e-22 79.8 9.8 5.2e-05 23.7 0.2 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG25177.1 - 2.2e-17 63.2 14.0 0.00064 20.2 0.2 7.8 3 2 6 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG25177.1 - 3.3e-17 62.3 13.9 0.003 17.8 0.1 9.5 2 1 6 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG25177.1 - 2.7e-09 36.5 4.4 15 6.5 0.0 9.1 8 2 2 10 10 10 1 Ankyrin repeat DUF5049 PF16468.5 EGG25177.1 - 2.3e-08 33.8 2.5 2.3 8.2 0.0 7.1 3 3 4 7 7 7 2 Domain of unknown function (DUF5049) Ank PF00023.30 EGG25177.1 - 0.0034 17.8 4.0 66 4.2 0.1 7.2 5 2 1 6 6 6 0 Ankyrin repeat Tom7 PF08038.12 EGG25177.1 - 0.014 15.0 0.0 0.66 9.7 0.0 3.1 3 0 0 3 3 3 0 TOM7 family Vps23_core PF09454.10 EGG25177.1 - 0.076 13.0 0.0 1.9 8.5 0.0 3.1 3 0 0 3 3 3 0 Vps23 core domain NdhO PF11910.8 EGG25177.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O SET PF00856.28 EGG25177.1 - 1.4 9.3 4.0 1.6 9.1 2.7 2.1 1 1 0 1 1 1 0 SET domain Pkinase_Tyr PF07714.17 EGG25178.1 - 9.2e-42 143.1 0.0 2.6e-41 141.6 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG25178.1 - 2.7e-38 131.8 0.0 2.7e-38 131.8 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain MORN PF02493.20 EGG25178.1 - 0.00019 21.1 0.6 0.18 11.8 0.1 3.0 2 0 0 2 2 2 2 MORN repeat TFIIA PF03153.13 EGG25178.1 - 0.00031 20.8 38.1 0.0015 18.6 10.5 3.2 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit RTP PF02334.16 EGG25178.1 - 0.0098 16.5 3.0 0.026 15.2 1.5 2.5 2 0 0 2 2 2 1 Replication terminator protein DUF4638 PF15472.6 EGG25178.1 - 0.32 10.7 4.0 0.8 9.4 4.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DDE_Tnp_IS240 PF13610.6 EGG25178.1 - 0.35 11.1 5.4 6.2 7.1 5.3 2.7 2 0 0 2 2 2 0 DDE domain SOG2 PF10428.9 EGG25178.1 - 0.39 9.9 45.3 0.18 11.0 10.0 3.3 3 0 0 3 3 3 0 RAM signalling pathway protein Pkinase_fungal PF17667.1 EGG25178.1 - 1.7 7.3 10.7 0.35 9.6 0.1 3.3 3 0 0 3 3 3 0 Fungal protein kinase DUF4407 PF14362.6 EGG25178.1 - 3.4 6.9 6.8 9.5 5.5 6.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 EGG25178.1 - 9.1 6.3 15.5 1.7 8.7 1.9 3.3 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF2890 PF11081.8 EGG25178.1 - 9.8 6.3 13.2 0.25 11.4 5.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) tRNA-synt_2 PF00152.20 EGG25179.1 - 7e-10 38.5 0.0 0.00079 18.6 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) Apc15p PF05841.11 EGG25179.1 - 0.93 10.3 8.1 10 7.0 2.8 2.4 2 0 0 2 2 2 0 Apc15p protein PNISR PF15996.5 EGG25181.1 - 0.026 14.8 1.0 0.038 14.3 1.0 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Pkinase PF00069.25 EGG25182.1 - 5.3e-11 42.4 0.1 4.2e-09 36.1 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 EGG25182.1 - 0.00055 18.8 0.2 0.00055 18.8 0.2 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGG25182.1 - 0.002 18.1 0.1 0.0037 17.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF5439 PF17507.2 EGG25182.1 - 0.014 15.6 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5439) FTA2 PF13095.6 EGG25182.1 - 0.025 14.2 0.2 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_Tyr PF07714.17 EGG25182.1 - 0.026 13.8 0.7 0.2 10.9 0.0 2.4 2 1 0 3 3 3 0 Protein tyrosine kinase eIF-3c_N PF05470.12 EGG25183.1 - 4.6e-124 414.9 38.1 2.3e-54 184.7 1.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EGG25183.1 - 3.7e-10 40.2 0.5 1.8e-09 38.1 0.2 2.3 2 0 0 2 2 2 1 PCI domain HTH_IclR PF09339.10 EGG25183.1 - 0.18 11.7 0.0 0.53 10.1 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain RasGEF_N PF00618.20 EGG25183.1 - 0.27 11.5 3.7 0.24 11.7 0.3 2.8 2 0 0 2 2 2 0 RasGEF N-terminal motif Nup192 PF11894.8 EGG25184.1 - 4.7e-28 97.0 11.1 4.7e-28 97.0 11.1 2.2 2 0 0 2 2 2 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF1117 PF06547.12 EGG25184.1 - 3.4 8.3 5.5 19 5.9 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Nup192 PF11894.8 EGG25185.1 - 8.2e-09 33.2 7.9 8.2e-09 33.2 7.9 2.1 2 0 0 2 2 2 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 Mak10 PF04112.13 EGG25185.1 - 0.028 13.9 0.1 0.079 12.5 0.0 1.8 2 0 0 2 2 2 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Phage_int_SAM_4 PF13495.6 EGG25185.1 - 0.055 14.0 0.2 0.34 11.4 0.0 2.5 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain ATP-synt_8 PF00895.20 EGG25185.1 - 0.24 11.9 3.8 30 5.2 0.0 3.5 3 0 0 3 3 3 0 ATP synthase protein 8 NDK PF00334.19 EGG25186.1 - 9.9e-56 187.5 0.0 1.1e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase CD34_antigen PF06365.12 EGG25187.1 - 0.015 14.9 0.2 0.032 13.8 0.2 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family NERD PF08378.11 EGG25187.1 - 0.1 13.1 0.1 0.37 11.3 0.1 1.9 1 0 0 1 1 1 0 Nuclease-related domain DUF4834 PF16118.5 EGG25187.1 - 0.18 12.8 4.7 0.84 10.6 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 EGG25187.1 - 0.21 12.5 1.1 0.54 11.2 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FAM221 PF14753.6 EGG25188.1 - 0.012 15.2 3.0 0.019 14.5 3.0 1.3 1 0 0 1 1 1 0 Protein FAM221A/B AIF_C PF14721.6 EGG25188.1 - 0.57 10.5 12.0 0.15 12.4 0.5 3.1 2 1 1 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Peptidase_C1 PF00112.23 EGG25189.1 - 4.5e-63 213.2 4.3 5.9e-63 212.9 4.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGG25189.1 - 3.1e-13 49.9 3.5 6.7e-13 48.9 3.5 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGG25189.1 - 4.3e-06 25.8 0.0 0.015 14.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DUF5491 PF17595.2 EGG25189.1 - 0.63 10.4 2.0 0.77 10.1 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5491) NTPase_I-T PF01931.18 EGG25190.1 - 1.1e-53 181.4 0.0 1.3e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 PB1 PF00564.24 EGG25191.1 - 9.6e-09 35.1 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Syja_N PF02383.18 EGG25192.1 - 2.8e-81 273.3 0.1 2.8e-81 273.3 0.1 2.7 3 1 0 3 3 3 1 SacI homology domain zf-C2HCIx2C PF10782.9 EGG25192.1 - 0.06 13.3 0.4 0.16 11.9 0.4 1.7 1 0 0 1 1 1 0 Zinc-finger SelP_N PF04592.14 EGG25192.1 - 1.4 8.3 23.4 0.066 12.6 16.7 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region PQ-loop PF04193.14 EGG25193.1 - 6.6e-22 77.0 13.3 7.1e-15 54.5 2.2 3.1 3 0 0 3 3 3 2 PQ loop repeat CH PF00307.31 EGG25194.1 - 2.3e-07 31.0 0.0 2.2e-06 27.8 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain PH PF00169.29 EGG25194.1 - 4.9e-07 30.2 0.3 2.7e-06 27.8 0.0 2.6 2 0 0 2 2 2 1 PH domain Consortin_C PF15281.6 EGG25195.1 - 1.2 9.2 3.6 1.1 9.3 0.2 2.3 2 0 0 2 2 2 0 Consortin C-terminus TssO PF17561.2 EGG25195.1 - 2.2 8.4 10.5 0.038 14.1 2.6 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssO Cnd3 PF12719.7 EGG25196.1 - 3.2e-26 92.2 0.1 3.2e-26 92.2 0.1 3.4 5 0 0 5 5 5 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 EGG25196.1 - 1.9e-06 27.7 0.8 0.32 11.4 0.0 6.1 7 0 0 7 7 7 1 HEAT repeat Cohesin_HEAT PF12765.7 EGG25196.1 - 1.9e-05 24.8 0.1 0.00055 20.2 0.0 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 EGG25196.1 - 4.9e-05 23.4 0.0 4.9e-05 23.4 0.0 3.7 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.6 EGG25196.1 - 0.048 14.1 5.7 3.3 8.1 0.4 4.0 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FKS1_dom1 PF14288.6 EGG25196.1 - 0.43 10.9 6.4 0.12 12.7 0.4 3.1 3 1 1 4 4 4 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Corazonin PF17308.2 EGG25196.1 - 0.44 10.9 15.4 0.061 13.7 3.7 3.0 3 0 0 3 3 3 0 Pro-corazonin Secretin_N_2 PF07655.13 EGG25196.1 - 0.95 10.0 17.7 2.9 8.5 7.1 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain FANCI_S2 PF14676.6 EGG25196.1 - 3.8 7.8 7.0 8.5 6.7 0.0 3.8 3 1 1 4 4 4 0 FANCI solenoid 2 EbsA PF17255.2 EGG25196.1 - 4.8 7.5 8.7 0.21 12.0 0.2 2.9 3 1 0 3 3 3 0 EbsA-like protein DUF1242 PF06842.12 EGG25198.1 - 9.6e-15 54.1 0.9 1.3e-14 53.7 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LST1 PF05083.13 EGG25198.1 - 0.15 12.4 0.2 0.19 12.0 0.2 1.2 1 0 0 1 1 1 0 LST-1 protein LSM PF01423.22 EGG25200.1 - 2.2e-09 36.9 2.4 2.2e-09 36.8 0.5 1.9 1 1 1 2 2 2 1 LSM domain DUF4653 PF15546.6 EGG25200.1 - 0.24 11.0 7.6 0.029 14.0 3.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) SR-25 PF10500.9 EGG25200.1 - 1.2 8.7 11.4 0.72 9.4 9.1 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2897 PF11446.8 EGG25200.1 - 7.4 6.5 6.2 13 5.8 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) VIT1 PF01988.19 EGG25201.1 - 1.1e-50 172.6 3.2 1.1e-50 172.6 3.2 1.7 2 0 0 2 2 2 1 VIT family B12D PF06522.11 EGG25201.1 - 0.018 14.8 0.1 0.64 9.9 0.0 3.3 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Presenilin PF01080.17 EGG25201.1 - 0.042 12.6 0.1 0.073 11.8 0.1 1.3 1 0 0 1 1 1 0 Presenilin DUF4349 PF14257.6 EGG25201.1 - 0.059 12.8 0.3 12 5.3 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF2149 PF09919.9 EGG25201.1 - 0.076 13.3 0.6 1.8 8.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) DUF4229 PF14012.6 EGG25201.1 - 0.079 13.1 0.4 0.079 13.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF4199 PF13858.6 EGG25201.1 - 0.14 12.6 4.6 3.4 8.0 1.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) DUF1449 PF07290.11 EGG25201.1 - 0.24 11.0 2.8 1.7 8.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1449) RMI1_N PF08585.12 EGG25201.1 - 0.34 10.6 2.1 0.49 10.1 2.1 1.1 1 0 0 1 1 1 0 RecQ mediated genome instability protein PBP1_TM PF14812.6 EGG25201.1 - 1.5 9.2 8.3 2.5 8.5 3.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2207 PF09972.9 EGG25201.1 - 2.7 6.7 7.4 5.5 5.6 4.2 2.5 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) FAM176 PF14851.6 EGG25201.1 - 7 6.3 11.2 0.43 10.2 0.7 2.3 1 1 1 2 2 2 0 FAM176 family RRN3 PF05327.11 EGG25201.1 - 9.2 4.7 6.8 13 4.2 6.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-C3HC4_2 PF13923.6 EGG25202.1 - 3.8e-08 33.1 10.3 7.2e-08 32.2 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGG25202.1 - 4.3e-08 32.9 5.9 7.1e-08 32.2 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGG25202.1 - 1.5e-06 28.0 10.0 3.1e-06 27.0 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGG25202.1 - 6.4e-06 26.4 9.8 1.2e-05 25.5 9.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGG25202.1 - 0.0001 22.2 8.1 0.00018 21.4 8.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGG25202.1 - 0.0003 20.6 6.3 0.00092 19.0 6.3 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGG25202.1 - 0.00045 20.2 10.8 0.00098 19.1 10.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 EGG25202.1 - 0.0019 18.3 2.1 0.0051 16.9 2.1 1.8 1 0 0 1 1 1 1 zinc RING finger of MSL2 Otopetrin PF03189.13 EGG25202.1 - 0.018 13.9 0.0 1.1 7.9 0.0 2.6 2 2 0 2 2 2 0 Otopetrin zf-rbx1 PF12678.7 EGG25202.1 - 0.16 12.3 5.8 0.46 10.8 5.8 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Caldesmon PF02029.15 EGG25202.1 - 0.3 9.8 29.3 0.014 14.2 22.0 2.2 2 0 0 2 2 2 0 Caldesmon zf-C3HC4_4 PF15227.6 EGG25202.1 - 1.5 9.0 10.7 7.6 6.8 10.8 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING VPS13 PF16908.5 EGG25203.1 - 1.1e-59 202.1 7.8 2.3e-59 201.0 6.3 8.4 9 1 2 11 11 11 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 EGG25203.1 - 8e-49 166.2 40.7 3.4e-45 154.3 5.6 9.0 7 2 0 7 7 7 3 Repeating coiled region of VPS13 SHR-BD PF06650.12 EGG25203.1 - 9.7e-43 146.5 3.9 5.5e-41 140.7 0.2 3.8 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 EGG25203.1 - 2.3e-37 127.7 4.0 2.1e-36 124.6 0.3 4.2 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 EGG25203.1 - 1.7e-36 125.6 11.5 7.8e-33 113.7 0.8 4.2 3 1 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 EGG25203.1 - 0.00063 20.1 0.0 0.0019 18.5 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain HEAT PF02985.22 EGG25204.1 - 2.1e-34 114.6 7.4 3e-05 23.9 0.0 9.2 10 0 0 10 10 9 7 HEAT repeat HEAT_2 PF13646.6 EGG25204.1 - 1.1e-20 73.8 0.0 1.3e-05 25.5 0.0 6.8 5 1 1 6 6 6 4 HEAT repeats Vac14_Fab1_bd PF12755.7 EGG25204.1 - 1.5e-11 44.7 0.1 0.0059 17.2 0.0 5.6 5 1 1 6 6 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGG25204.1 - 0.00045 20.7 0.1 16 6.1 0.0 4.7 4 0 0 4 4 4 0 HEAT-like repeat Arm PF00514.23 EGG25204.1 - 0.00083 19.3 0.7 1.2e+02 2.9 0.1 5.6 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat Nipped-B_C PF12830.7 EGG25204.1 - 0.053 13.5 0.6 33 4.4 0.0 3.8 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus Pex2_Pex12 PF04757.14 EGG25204.1 - 0.054 13.1 0.8 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region Cohesin_HEAT PF12765.7 EGG25204.1 - 0.061 13.6 2.2 43 4.5 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DUF5601 PF18151.1 EGG25204.1 - 0.1 13.0 0.4 0.59 10.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) BET PF17035.5 EGG25204.1 - 0.11 12.7 1.6 0.2 11.8 0.1 2.3 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation RasGEF_N PF00618.20 EGG25204.1 - 0.25 11.6 4.4 6.3 7.1 0.6 3.2 2 1 0 2 2 2 0 RasGEF N-terminal motif RabGAP-TBC PF00566.18 EGG25204.1 - 2.2 7.9 7.3 6.9 6.3 2.4 2.5 2 0 0 2 2 2 0 Rab-GTPase-TBC domain Ras PF00071.22 EGG25205.1 - 1.5e-37 128.7 0.1 1.8e-37 128.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG25205.1 - 1.5e-14 54.2 0.0 2.3e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG25205.1 - 1.2e-07 31.4 0.0 1.5e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_12 PF13087.6 EGG25206.1 - 1.6e-40 138.9 0.5 1.6e-40 138.9 0.5 2.6 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 EGG25206.1 - 5.7e-23 82.0 3.7 5.7e-23 82.0 3.7 4.2 3 2 0 3 3 3 1 AAA domain SAM_1 PF00536.30 EGG25206.1 - 3.4e-09 37.0 0.0 1.4e-08 35.0 0.0 2.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_30 PF13604.6 EGG25206.1 - 9.4e-08 32.0 0.0 0.00078 19.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain SAM_2 PF07647.17 EGG25206.1 - 6.6e-07 29.3 0.0 1.9e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_19 PF13245.6 EGG25206.1 - 9.2e-07 29.3 0.0 1.5e-05 25.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGG25206.1 - 0.015 15.6 1.4 1 9.6 0.0 3.8 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EGG25206.1 - 0.018 15.5 0.3 0.46 10.8 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Ldh_2 PF02615.14 EGG25206.1 - 0.071 12.2 0.1 1 8.4 0.1 2.1 2 0 0 2 2 2 0 Malate/L-lactate dehydrogenase FNIP PF05725.12 EGG25208.1 - 0.0069 16.5 9.6 6.8 7.0 0.2 6.0 5 3 1 6 6 6 4 FNIP Repeat FNIP PF05725.12 EGG25209.1 - 0.003 17.7 2.5 4.1 7.6 0.0 5.4 4 2 0 5 5 5 1 FNIP Repeat PDZ_1 PF12812.7 EGG25209.1 - 0.029 14.4 0.0 0.076 13.0 0.0 1.7 1 0 0 1 1 1 0 PDZ-like domain Ank_4 PF13637.6 EGG25210.1 - 8.9e-17 61.2 1.5 0.0016 19.0 0.0 9.0 8 1 1 9 9 9 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG25210.1 - 4.9e-16 59.1 2.4 0.00011 22.7 0.0 7.5 3 1 6 9 9 9 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG25210.1 - 2e-07 31.1 0.1 0.43 10.9 0.0 7.4 6 2 2 8 8 8 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG25210.1 - 0.0091 16.4 11.9 36 5.4 0.0 9.3 13 0 0 13 13 13 0 Ankyrin repeat Ank PF00023.30 EGG25210.1 - 0.11 13.0 2.6 30 5.3 0.1 4.8 5 1 1 6 6 6 0 Ankyrin repeat MgsA_C PF12002.8 EGG25211.1 - 1.6e-57 194.1 0.0 3.6e-57 192.9 0.0 1.6 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EGG25211.1 - 1.7e-21 76.3 0.2 4.3e-21 75.0 0.2 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EGG25211.1 - 2.1e-15 57.3 0.9 4.3e-15 56.3 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGG25211.1 - 7.7e-15 55.0 0.0 1.7e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EGG25211.1 - 1.6e-07 31.4 0.0 6.7e-07 29.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 EGG25211.1 - 5.9e-06 26.3 2.4 7.4e-06 26.0 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGG25211.1 - 6.2e-06 25.7 0.2 0.029 13.7 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 EGG25211.1 - 9.3e-06 25.8 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EGG25211.1 - 9.9e-06 26.0 0.1 0.0004 20.8 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 EGG25211.1 - 1e-05 25.3 0.0 0.022 14.5 0.0 2.4 1 1 1 2 2 2 2 Sigma-54 interaction domain ATP-synt_ab PF00006.25 EGG25211.1 - 0.00011 21.9 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 EGG25211.1 - 0.00017 21.9 0.2 0.015 15.6 0.1 2.7 1 1 1 2 2 2 1 AAA domain zf-WRNIP1_ubi PF18279.1 EGG25211.1 - 0.00039 20.8 0.3 0.0026 18.3 0.1 2.6 2 0 0 2 2 1 1 Werner helicase-interacting protein 1 ubiquitin-binding domain Viral_helicase1 PF01443.18 EGG25211.1 - 0.00084 19.1 0.0 0.00084 19.1 0.0 2.8 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EGG25211.1 - 0.00096 19.1 0.1 0.044 13.7 0.0 2.6 1 1 2 3 3 3 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EGG25211.1 - 0.0027 16.9 0.4 0.0098 15.1 0.0 2.1 3 0 0 3 3 3 1 NB-ARC domain AAA_2 PF07724.14 EGG25211.1 - 0.0037 17.4 0.0 0.013 15.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EGG25211.1 - 0.0064 17.0 0.0 0.0064 17.0 0.0 3.2 4 0 0 4 4 3 1 AAA domain TniB PF05621.11 EGG25211.1 - 0.0069 15.8 0.0 0.17 11.3 0.0 2.7 1 1 0 2 2 2 1 Bacterial TniB protein TIP49 PF06068.13 EGG25211.1 - 0.013 14.7 0.0 0.03 13.5 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 EGG25211.1 - 0.014 15.3 0.0 0.072 12.9 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGG25211.1 - 0.019 15.3 0.0 0.019 15.3 0.0 2.9 3 0 0 3 3 1 0 RNA helicase ABC_tran PF00005.27 EGG25211.1 - 0.028 14.9 0.0 0.028 14.9 0.0 2.9 4 0 0 4 4 2 0 ABC transporter AAA_30 PF13604.6 EGG25211.1 - 0.036 13.8 0.0 0.45 10.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGG25211.1 - 0.04 13.6 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGG25211.1 - 0.041 14.1 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGG25211.1 - 0.05 13.9 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGG25211.1 - 0.069 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF4377 PF14302.6 EGG25211.1 - 0.082 13.0 0.8 0.23 11.5 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4377) IstB_IS21 PF01695.17 EGG25211.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein p450 PF00067.22 EGG25212.1 - 7.2e-86 288.8 0.0 8.7e-86 288.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PP2C PF00481.21 EGG25213.1 - 1.4e-55 188.7 0.0 4.7e-55 187.0 0.0 1.9 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase_Tyr PF07714.17 EGG25213.1 - 1.2e-43 149.3 0.0 2.4e-43 148.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGG25213.1 - 2.7e-36 125.3 0.0 7e-36 123.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 EGG25213.1 - 9.1e-36 123.5 0.0 1.3e-33 116.4 0.0 2.4 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain cNMP_binding PF00027.29 EGG25213.1 - 9e-23 80.2 0.1 2.8e-11 43.3 0.0 3.1 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Roc PF08477.13 EGG25213.1 - 6.8e-18 65.0 0.1 2.9e-17 63.0 0.1 2.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GRAM PF02893.20 EGG25213.1 - 9.5e-15 54.5 1.8 2.3e-14 53.2 1.8 1.7 1 0 0 1 1 1 1 GRAM domain RasGEF_N PF00618.20 EGG25213.1 - 4.6e-11 42.9 0.4 4.6e-11 42.9 0.4 3.3 3 0 0 3 3 2 1 RasGEF N-terminal motif DEP PF00610.21 EGG25213.1 - 2e-09 37.4 0.0 6.8e-09 35.7 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ras PF00071.22 EGG25213.1 - 9.9e-09 35.0 3.0 4.2e-08 32.9 3.0 2.0 1 1 0 1 1 1 1 Ras family APH PF01636.23 EGG25213.1 - 0.00035 20.6 0.0 0.0008 19.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family PP2C_2 PF13672.6 EGG25213.1 - 0.026 14.2 0.1 0.082 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 2C AAA_16 PF13191.6 EGG25213.1 - 0.028 14.8 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF2316 PF10078.9 EGG25213.1 - 0.055 13.7 0.2 1.6 9.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) ELMO_CED12 PF04727.13 EGG25214.1 - 1.2e-52 178.6 0.4 1.2e-52 178.6 0.4 2.0 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.8 EGG25214.1 - 3.6e-09 36.8 0.3 0.0003 20.7 0.0 2.6 1 1 0 2 2 2 2 Domain of unknown function (DUF3361) PH_12 PF16457.5 EGG25214.1 - 2.3 8.7 16.8 0.28 11.7 2.8 4.0 4 1 0 4 4 4 0 Pleckstrin homology domain TMEM171 PF15471.6 EGG25215.1 - 5 6.0 6.1 10 5.0 6.1 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 Ribosomal_L33 PF00471.20 EGG25216.1 - 4.8e-11 42.9 0.3 6.1e-11 42.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 LRR_4 PF12799.7 EGG25218.1 - 1.7e-30 104.5 73.6 0.0031 17.9 1.0 18.1 8 5 11 20 20 20 16 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGG25218.1 - 2.1e-09 36.7 54.6 1.1 9.5 0.1 19.0 22 0 0 22 22 22 4 Leucine Rich repeat LRR_8 PF13855.6 EGG25218.1 - 7e-05 22.5 40.7 0.047 13.5 3.1 10.8 9 3 3 12 12 12 2 Leucine rich repeat DNase_NucA_NucB PF14040.6 EGG25218.1 - 0.23 11.9 9.2 6 7.3 7.4 2.5 1 1 1 2 2 2 0 Deoxyribonuclease NucA/NucB UPAR_LY6_2 PF16975.5 EGG25218.1 - 0.33 11.2 4.0 22 5.3 0.1 3.5 2 1 0 2 2 2 0 Ly6/PLAUR domain-containing protein 6, Lypd6 Amidohydro_1 PF01979.20 EGG25219.1 - 4.3e-60 203.8 0.4 5.3e-60 203.5 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGG25219.1 - 8.3e-09 35.4 0.1 1.8e-06 27.7 0.0 2.8 2 1 0 3 3 3 2 Amidohydrolase family DHR-2 PF06920.13 EGG25220.1 - 1.3e-172 575.1 5.3 2.5e-172 574.2 5.3 1.5 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 EGG25220.1 - 3e-45 154.4 3.7 1.6e-44 152.0 3.3 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 EGG25220.1 - 0.00017 22.0 0.2 0.00067 20.1 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) CLZ PF16526.5 EGG25220.1 - 0.11 12.9 0.1 0.48 10.8 0.1 2.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GAT PF03127.14 EGG25220.1 - 0.3 11.4 2.7 18 5.7 0.1 3.7 3 0 0 3 3 3 0 GAT domain DUF1538 PF07556.11 EGG25220.1 - 0.79 9.0 2.7 1.4 8.2 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1538) ABC2_membrane PF01061.24 EGG25222.1 - 5.6e-85 284.0 67.0 1.4e-45 155.3 24.9 2.7 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGG25222.1 - 1.2e-38 132.7 1.6 1.1e-18 68.0 0.0 3.0 4 0 0 4 4 2 2 ABC transporter PDR_CDR PF06422.12 EGG25222.1 - 3.8e-29 100.4 1.1 5.7e-24 83.8 0.0 3.4 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EGG25222.1 - 7.8e-09 36.0 0.7 2.9e-08 34.2 0.7 2.0 1 1 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EGG25222.1 - 4.8e-07 29.8 0.1 2.8e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGG25222.1 - 8.4e-06 25.4 0.3 0.0059 16.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGG25222.1 - 3.9e-05 23.6 0.0 0.11 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGG25222.1 - 6.7e-05 23.3 0.0 0.2 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 EGG25222.1 - 0.00012 21.3 22.3 0.00012 21.3 22.3 3.8 3 1 1 4 4 2 1 ABC-2 family transporter protein AAA_22 PF13401.6 EGG25222.1 - 0.00031 21.0 0.2 0.76 10.0 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGG25222.1 - 0.0019 17.8 0.1 0.0067 16.0 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGG25222.1 - 0.0075 16.4 0.1 0.87 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGG25222.1 - 0.02 14.6 0.2 2.2 7.9 0.3 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGG25222.1 - 0.033 13.5 0.0 5.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 EGG25222.1 - 0.056 14.0 4.0 0.99 9.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EGG25222.1 - 0.074 13.1 0.1 7.6 6.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 EGG25222.1 - 0.098 12.2 1.4 1.5 8.4 0.7 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EGG25222.1 - 0.12 12.8 0.1 6 7.3 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGG25222.1 - 0.12 12.7 0.1 23 5.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 EGG25222.1 - 0.2 11.4 0.0 4.7 6.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 EGG25222.1 - 4.6 7.5 5.3 1.4 9.1 0.8 2.4 3 0 0 3 3 2 0 AAA domain ABC2_membrane PF01061.24 EGG25223.1 - 1.8e-90 302.0 65.7 3.8e-46 157.2 25.4 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGG25223.1 - 2.3e-40 138.3 0.0 3.2e-19 69.8 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 EGG25223.1 - 1.6e-29 101.7 2.9 1.8e-26 91.8 0.1 4.1 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 EGG25223.1 - 3.4e-09 37.2 0.1 8.7e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EGG25223.1 - 2.8e-08 33.8 0.2 1.8e-05 24.7 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase ABC2_membrane_3 PF12698.7 EGG25223.1 - 1e-06 28.1 65.6 2e-06 27.1 21.8 3.6 2 2 1 3 3 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 EGG25223.1 - 4.7e-06 26.2 0.4 0.0059 16.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGG25223.1 - 7e-06 26.1 0.0 0.049 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGG25223.1 - 9.3e-05 22.9 0.0 0.066 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGG25223.1 - 0.0022 18.3 0.1 0.7 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGG25223.1 - 0.0027 17.3 0.2 0.0069 16.0 0.1 1.7 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 EGG25223.1 - 0.0043 17.1 0.1 3.5 7.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 EGG25223.1 - 0.0064 16.2 0.2 2.3 7.9 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGG25223.1 - 0.011 16.3 0.1 0.54 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3600 PF12207.8 EGG25223.1 - 0.027 14.4 0.0 0.34 10.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) RNA_helicase PF00910.22 EGG25223.1 - 0.067 13.6 0.3 21 5.6 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 EGG25223.1 - 0.1 12.8 0.0 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGG25223.1 - 0.11 12.1 0.5 1.4 8.4 0.5 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 EGG25223.1 - 0.11 12.4 0.0 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 EGG25223.1 - 0.18 11.1 0.0 6 6.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 EGG25223.1 - 0.27 11.5 0.6 1.4 9.2 0.7 2.1 2 0 0 2 2 2 0 AAA domain PP2C PF00481.21 EGG25224.1 - 5.1e-57 193.5 1.4 5.1e-57 193.5 1.4 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGG25224.1 - 0.00079 19.1 0.1 0.0023 17.6 0.1 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C DUF761 PF05553.11 EGG25224.1 - 0.0097 15.4 1.0 0.047 13.2 0.0 2.4 2 0 0 2 2 2 1 Cotton fibre expressed protein NTPase_1 PF03266.15 EGG25224.1 - 0.052 13.5 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 NTPase MHB PF16525.5 EGG25224.1 - 0.13 12.6 2.5 0.47 10.7 2.5 2.0 1 0 0 1 1 1 0 Haemophore, haem-binding dNK PF01712.19 EGG25225.1 - 2.7e-50 171.1 1.0 3.4e-50 170.7 1.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 EGG25225.1 - 2.5e-10 41.0 0.1 5.6e-10 39.9 0.0 1.6 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EGG25225.1 - 5.3e-07 29.5 0.2 3.6e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 EGG25225.1 - 0.00017 21.9 0.0 0.00024 21.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 EGG25225.1 - 0.00093 19.3 0.1 0.09 12.9 0.1 2.4 2 1 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.6 EGG25225.1 - 0.0052 16.9 0.0 0.015 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Herpes_TK PF00693.18 EGG25225.1 - 0.0098 15.2 0.4 0.021 14.1 0.0 1.7 2 0 0 2 2 2 1 Thymidine kinase from herpesvirus AAA_17 PF13207.6 EGG25225.1 - 0.012 16.0 0.2 5.5 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGG25225.1 - 0.022 14.8 0.3 0.37 10.8 0.0 2.5 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EGG25225.1 - 0.042 13.0 1.1 0.24 10.5 0.3 2.4 1 1 0 2 2 2 0 NB-ARC domain CoaE PF01121.20 EGG25225.1 - 0.12 12.1 0.0 0.79 9.4 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_29 PF13555.6 EGG25225.1 - 0.12 12.1 0.1 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGG25225.1 - 0.16 12.3 0.1 2.3 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Profilin PF00235.19 EGG25226.1 - 8e-05 22.9 0.0 0.004 17.4 0.0 2.3 2 0 0 2 2 2 2 Profilin Phos_pyr_kin PF08543.12 EGG25227.1 - 3.5e-15 56.0 0.0 5e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EGG25227.1 - 7.2e-10 38.7 0.1 3.2e-09 36.5 0.0 2.1 3 0 0 3 3 3 1 pfkB family carbohydrate kinase Thr_dehydrat_C PF00585.18 EGG25227.1 - 0.15 11.8 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase PPR_3 PF13812.6 EGG25227.1 - 0.19 11.9 0.7 0.42 10.7 0.1 1.8 2 0 0 2 2 2 0 Pentatricopeptide repeat domain SCAI PF12070.8 EGG25229.1 - 9.3e-205 681.5 18.9 9.3e-205 681.5 18.9 1.8 2 0 0 2 2 2 1 Protein SCAI AlgF PF11182.8 EGG25230.1 - 0.082 12.7 0.3 0.15 11.8 0.3 1.3 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF TFIIS_M PF07500.14 EGG25231.1 - 4.5e-23 81.9 3.2 9.4e-23 80.8 3.2 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EGG25231.1 - 7.2e-19 67.4 8.1 1.2e-18 66.7 8.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EGG25231.1 - 2.1e-07 30.8 1.1 2.1e-07 30.8 1.1 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Cep57_CLD_2 PF14197.6 EGG25231.1 - 0.12 12.5 3.4 1.9 8.7 0.1 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Baculo_LEF5_C PF11792.8 EGG25231.1 - 0.14 11.8 0.5 0.81 9.4 0.0 2.6 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_12 PF11331.8 EGG25231.1 - 1.3 8.9 4.7 13 5.7 0.2 3.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain SAYSvFN PF10260.9 EGG25232.1 - 1.3e-05 25.0 0.7 0.00012 21.9 0.7 2.1 1 1 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) Telomere_reg-2 PF10193.9 EGG25234.1 - 0.34 11.4 6.7 1.1 9.8 0.0 4.5 6 0 0 6 6 6 0 Telomere length regulation protein ABC2_membrane PF01061.24 EGG25235.1 - 1.8e-81 272.6 64.8 1.3e-43 148.9 22.8 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGG25235.1 - 2.2e-38 131.9 0.0 9.2e-19 68.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGG25235.1 - 5.7e-33 112.7 0.9 3.2e-25 87.8 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EGG25235.1 - 2e-09 38.0 0.1 5.3e-09 36.6 0.1 1.8 1 1 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EGG25235.1 - 6e-09 36.0 0.5 1.1e-06 28.7 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGG25235.1 - 2.8e-06 27.0 0.4 0.0059 16.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 EGG25235.1 - 8.2e-06 25.2 17.3 8.2e-06 25.2 17.3 3.0 2 1 1 3 3 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGG25235.1 - 5e-05 23.3 0.0 0.1 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGG25235.1 - 0.00013 22.4 0.0 0.21 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGG25235.1 - 0.0014 18.9 0.1 0.76 10.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGG25235.1 - 0.0017 18.0 0.1 0.0067 16.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGG25235.1 - 0.0097 15.6 0.1 2.1 8.0 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGG25235.1 - 0.019 15.5 4.0 1 9.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EGG25235.1 - 0.022 14.9 0.1 0.87 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGG25235.1 - 0.022 14.8 0.1 7.6 6.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EGG25235.1 - 0.042 13.1 0.0 5.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 EGG25235.1 - 0.048 13.6 0.2 4.6 7.1 0.0 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain cobW PF02492.19 EGG25235.1 - 0.086 12.4 0.9 1.5 8.4 0.7 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EGG25235.1 - 0.1 13.0 0.2 5.2 7.5 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EGG25235.1 - 0.14 11.8 0.0 3.5 7.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 EGG25235.1 - 0.16 11.9 0.3 7.4 6.5 0.6 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EGG25235.1 - 0.4 10.9 1.1 1.4 9.1 0.8 2.1 2 0 0 2 2 2 0 AAA domain COX17 PF05051.13 EGG25236.1 - 1e-19 70.6 7.9 1.2e-19 70.3 7.9 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) GCS PF03074.16 EGG25237.1 - 2e-168 560.4 0.2 2.6e-168 560.1 0.2 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase LIM PF00412.22 EGG25239.1 - 8.1e-19 67.6 31.0 2.7e-09 37.1 11.8 2.6 2 0 0 2 2 2 2 LIM domain Borrelia_P83 PF05262.11 EGG25239.1 - 0.002 16.7 48.0 0.002 16.7 48.0 6.9 3 1 4 7 7 7 1 Borrelia P83/100 protein zf-C3HC4_2 PF13923.6 EGG25239.1 - 5 7.1 20.7 6 6.8 2.5 4.3 2 2 2 4 4 4 0 Zinc finger, C3HC4 type (RING finger) MLIP PF15274.6 EGG25241.1 - 0.0028 17.6 3.0 0.0035 17.3 2.5 1.3 1 1 0 1 1 1 1 Muscular LMNA-interacting protein DUF5009 PF16401.5 EGG25241.1 - 0.14 11.6 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5009) DUF1374 PF07118.11 EGG25241.1 - 0.27 11.8 4.7 0.16 12.5 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) DENN PF02141.21 EGG25242.1 - 3.7e-35 121.6 6.0 3.7e-35 121.6 6.0 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 EGG25242.1 - 1.3e-07 32.3 0.0 8e-07 29.7 0.0 2.5 1 0 0 1 1 1 1 uDENN domain LIM PF00412.22 EGG25242.1 - 0.00018 21.7 14.5 0.0039 17.4 6.4 2.8 2 1 0 2 2 2 2 LIM domain SPA PF08616.10 EGG25242.1 - 0.00063 19.7 0.2 0.0018 18.2 0.2 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Zn_ribbon_2 PF12674.7 EGG25242.1 - 0.1 13.3 4.9 0.22 12.2 0.3 3.1 2 0 0 2 2 2 0 Putative zinc ribbon domain TAF1_subA PF14929.6 EGG25243.1 - 2.3e-07 30.6 0.0 6.3e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 TAF RNA Polymerase I subunit A TPR_17 PF13431.6 EGG25243.1 - 0.011 16.1 0.0 0.043 14.2 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Zip PF02535.22 EGG25243.1 - 0.35 10.0 2.8 5.5 6.1 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter CDC45 PF02724.14 EGG25243.1 - 0.79 7.9 14.5 0.039 12.2 3.4 2.1 2 0 0 2 2 2 0 CDC45-like protein RIH_assoc PF08454.11 EGG25244.1 - 0.17 11.7 1.7 0.46 10.3 0.3 2.5 2 0 0 2 2 2 0 RyR and IP3R Homology associated DUF3447 PF11929.8 EGG25244.1 - 2.5 8.1 9.2 7 6.7 0.1 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3447) GCD14 PF08704.10 EGG25245.1 - 1.5e-90 303.2 0.1 3.5e-90 302.0 0.1 1.6 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 EGG25245.1 - 2.6e-08 33.8 0.0 4.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 EGG25245.1 - 3.3e-06 26.8 0.0 1.1e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_25 PF13649.6 EGG25245.1 - 0.0008 20.1 0.0 0.0017 19.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGG25245.1 - 0.0029 18.6 0.0 0.0052 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG25245.1 - 0.0051 17.5 4.4 0.069 13.9 0.0 3.0 2 1 1 3 3 3 1 Methyltransferase domain PCMT PF01135.19 EGG25245.1 - 0.0053 16.5 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EGG25245.1 - 0.0082 15.7 0.0 0.034 13.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Gcd10p PF04189.13 EGG25245.1 - 0.029 13.5 0.0 0.029 13.5 0.0 1.9 2 0 0 2 2 2 0 Gcd10p family BAG PF02179.16 EGG25245.1 - 0.051 14.0 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 BAG domain Ubie_methyltran PF01209.18 EGG25245.1 - 0.052 12.9 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EGG25245.1 - 0.084 13.5 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 EGG25245.1 - 0.095 11.8 0.0 0.26 10.4 0.0 1.7 1 1 0 1 1 1 0 Fibrillarin Thump_like PF18096.1 EGG25245.1 - 0.18 11.7 0.6 1.3 9.0 0.3 2.4 3 0 0 3 3 2 0 THUMP domain-like Menin PF05053.13 EGG25245.1 - 0.48 8.7 2.6 0.6 8.4 2.6 1.1 1 0 0 1 1 1 0 Menin Tyrosinase PF00264.20 EGG25246.1 - 9e-45 153.7 0.0 2.8e-24 86.7 0.0 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase DAO PF01266.24 EGG25247.1 - 3.4e-53 181.5 0.0 5.8e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase RasGEF PF00617.19 EGG25247.1 - 2.7e-52 177.5 3.1 1.1e-51 175.6 1.1 2.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGG25247.1 - 2.8e-05 24.3 0.6 2.8e-05 24.3 0.6 4.3 6 1 0 6 6 6 1 RasGEF N-terminal motif FAD_binding_3 PF01494.19 EGG25247.1 - 3.8e-05 23.1 0.0 0.019 14.2 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EGG25247.1 - 0.021 14.1 0.5 0.48 9.6 0.6 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGG25247.1 - 0.098 12.9 0.4 0.74 10.1 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain CMS1 PF14617.6 EGG25248.1 - 6e-16 58.6 10.2 2.2e-14 53.4 4.0 2.9 1 1 1 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EGG25248.1 - 0.021 14.6 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase V-set PF07686.17 EGG25248.1 - 0.048 13.8 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Immunoglobulin V-set domain Pkinase PF00069.25 EGG25249.1 - 5.5e-58 196.4 0.0 7.7e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG25249.1 - 1.2e-45 155.9 0.0 1.8e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EGG25249.1 - 0.0053 16.4 0.0 0.57 9.8 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGG25249.1 - 0.0063 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGG25249.1 - 0.097 12.6 0.1 2 8.3 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3844 PF12955.7 EGG25250.1 - 0.64 10.2 4.6 5.8 7.1 2.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) EGF_2 PF07974.13 EGG25250.1 - 4 7.9 15.4 0.04 14.3 7.2 1.9 2 0 0 2 2 2 0 EGF-like domain DUF3290 PF11694.8 EGG25250.1 - 8.7 6.3 7.0 12 5.8 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3290) HA2 PF04408.23 EGG25251.1 - 1.7e-26 92.6 0.1 1.7e-26 92.6 0.1 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGG25251.1 - 7e-25 87.2 0.0 1.6e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGG25251.1 - 3.5e-12 46.6 0.0 1.1e-11 45.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EGG25251.1 - 1.8e-09 37.8 1.0 1.8e-09 37.8 1.0 2.3 2 1 0 2 2 2 1 S1 RNA binding domain DEAD PF00270.29 EGG25251.1 - 2.4e-06 27.4 0.0 1.2e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGG25251.1 - 1.4e-05 25.4 0.1 5.2e-05 23.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGG25251.1 - 0.00016 21.5 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGG25251.1 - 0.0049 16.0 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EGG25251.1 - 0.022 15.1 0.0 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 EGG25251.1 - 0.081 12.9 0.0 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Microtubule binding PhoH PF02562.16 EGG25251.1 - 0.096 12.1 0.0 0.3 10.5 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 EGG25251.1 - 0.12 12.8 0.4 0.31 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Abhydro_lipase PF04083.16 EGG25252.1 - 2.3e-23 81.5 0.1 4.8e-23 80.5 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGG25252.1 - 5.9e-15 55.6 0.4 1.5e-11 44.5 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGG25252.1 - 0.00028 20.2 0.0 0.033 13.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF4604 PF15377.6 EGG25253.1 - 0.0012 19.4 23.6 0.0019 18.7 23.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) VASt PF16016.5 EGG25253.1 - 0.1 13.0 1.9 0.15 12.4 1.9 1.3 1 0 0 1 1 1 0 VAD1 Analog of StAR-related lipid transfer domain Vhr1 PF04001.13 EGG25253.1 - 0.11 12.8 3.8 0.11 12.8 2.2 1.9 2 0 0 2 2 2 0 Transcription factor Vhr1 ZYG-11_interact PF05884.12 EGG25253.1 - 0.33 10.3 5.4 0.42 10.0 5.4 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 HicB_lk_antitox PF15919.5 EGG25253.1 - 0.36 11.0 3.8 0.6 10.2 3.8 1.3 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system BK_channel_a PF03493.18 EGG25254.1 - 1.6e-21 76.3 1.0 3.3e-21 75.3 0.3 2.0 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EGG25254.1 - 6.6e-12 45.2 4.2 6.6e-12 45.2 4.2 2.2 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 EGG25254.1 - 9.8e-11 41.9 0.0 9.8e-08 32.3 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain Zip PF02535.22 EGG25254.1 - 0.053 12.7 1.5 6.4 5.9 1.5 2.9 1 1 0 1 1 1 0 ZIP Zinc transporter SDA1 PF05285.12 EGG25254.1 - 0.97 8.8 22.0 1.8 7.9 22.0 1.4 1 0 0 1 1 1 0 SDA1 RCC1 PF00415.18 EGG25255.1 - 1e-56 189.3 9.5 8.9e-12 45.4 0.1 8.3 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGG25255.1 - 4.5e-38 128.3 19.3 1.9e-10 40.3 1.0 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat DUF3314 PF11771.8 EGG25255.1 - 0.27 11.4 1.3 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3314) SecG PF03840.14 EGG25256.1 - 0.033 14.3 0.5 0.043 13.9 0.5 1.1 1 0 0 1 1 1 0 Preprotein translocase SecG subunit DUF4844 PF16133.5 EGG25258.1 - 0.016 15.7 0.6 0.043 14.4 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) Acetyltransf_10 PF13673.7 EGG25259.1 - 2.4e-13 50.2 0.0 3.2e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGG25259.1 - 7.9e-13 48.7 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGG25259.1 - 1.7e-10 41.1 0.1 4e-10 40.0 0.1 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGG25259.1 - 0.0023 18.0 0.0 0.0035 17.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGG25259.1 - 0.011 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_15 PF17013.5 EGG25259.1 - 0.012 15.1 0.2 0.014 14.8 0.2 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase PanZ PF12568.8 EGG25259.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ ELP6 PF09807.9 EGG25261.1 - 0.11 11.9 0.1 0.13 11.7 0.1 1.0 1 0 0 1 1 1 0 Elongation complex protein 6 Spt20 PF12090.8 EGG25264.1 - 7.8e-06 25.7 19.0 7.8e-06 25.7 19.0 2.2 2 0 0 2 2 2 1 Spt20 family AIF_C PF14721.6 EGG25264.1 - 0.0023 18.3 1.4 0.0023 18.3 1.4 2.2 2 0 0 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4834 PF16118.5 EGG25264.1 - 0.0029 18.5 4.1 0.0029 18.5 4.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) N6_N4_Mtase PF01555.18 EGG25264.1 - 0.0038 17.0 0.0 0.016 14.9 0.0 2.0 1 1 0 1 1 1 1 DNA methylase WASH-7_C PF14746.6 EGG25264.1 - 0.0063 16.2 16.4 0.12 12.0 7.4 2.4 2 0 0 2 2 2 2 WASH complex subunit 7, C-terminal TCP PF03634.13 EGG25264.1 - 0.0078 16.8 5.3 0.064 13.8 1.2 2.2 2 0 0 2 2 2 1 TCP family transcription factor DUF5308 PF17233.2 EGG25264.1 - 0.0085 16.3 1.4 0.011 16.0 0.1 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5308) U1snRNP70_N PF12220.8 EGG25264.1 - 0.012 16.2 1.7 0.012 16.2 1.7 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Rxt3 PF08642.10 EGG25264.1 - 0.036 14.8 3.0 0.24 12.2 0.2 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 TFIIA PF03153.13 EGG25264.1 - 0.15 12.0 30.1 0.021 14.8 20.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Apc15p PF05841.11 EGG25264.1 - 0.2 12.4 18.9 0.67 10.8 8.0 2.4 2 0 0 2 2 2 0 Apc15p protein Neur_chan_memb PF02932.16 EGG25264.1 - 0.22 11.6 3.6 0.17 11.9 0.6 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 EGG25264.1 - 0.49 10.3 1.9 0.54 10.2 0.1 1.9 2 0 0 2 2 2 0 N-glycosylation protein Connexin PF00029.19 EGG25264.1 - 1.1 9.0 10.7 2.3 7.9 5.3 2.1 2 0 0 2 2 2 0 Connexin CPSF100_C PF13299.6 EGG25264.1 - 1.6 8.9 8.3 0.62 10.2 3.4 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PRC2_HTH_1 PF18118.1 EGG25264.1 - 1.6 9.6 8.7 1.1 10.1 3.0 2.8 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain Pet20 PF08692.10 EGG25264.1 - 1.9 9.2 8.0 0.4 11.4 1.0 2.3 2 0 0 2 2 2 0 Mitochondrial protein Pet20 DUF2098 PF09871.9 EGG25264.1 - 2.1 8.8 10.1 0.47 10.8 6.1 2.0 2 0 0 2 2 1 0 Uncharacterized protein conserved in archaea (DUF2098) TERB2 PF15101.6 EGG25264.1 - 2.2 8.3 16.3 0.16 12.0 9.2 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF3371 PF11851.8 EGG25264.1 - 2.4 9.3 13.5 0.27 12.4 6.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) OATP PF03137.20 EGG25264.1 - 2.6 6.2 8.0 0.16 10.2 1.1 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EIIBC-GUT_N PF03612.14 EGG25264.1 - 2.8 7.7 10.9 0.37 10.5 5.2 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus ANAPC_CDC26 PF10471.9 EGG25264.1 - 3.1 8.7 30.4 1.5 9.7 23.6 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 PP_kinase_N PF13089.6 EGG25264.1 - 4 7.8 16.3 0.059 13.7 5.7 2.9 3 0 0 3 3 3 0 Polyphosphate kinase N-terminal domain CLN3 PF02487.17 EGG25264.1 - 4.1 6.4 9.4 0.57 9.2 3.9 1.9 2 0 0 2 2 2 0 CLN3 protein Serinc PF03348.15 EGG25264.1 - 6.3 5.6 6.4 1.1 8.1 2.6 1.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) ATAD4 PF15321.6 EGG25264.1 - 7.4 8.0 12.7 2.4 9.5 6.2 2.4 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Pex14_N PF04695.13 EGG25264.1 - 8.4 7.0 20.9 1.1 9.8 14.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EF-hand_1 PF00036.32 EGG25265.1 - 4.6e-09 35.2 0.0 0.00011 21.5 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGG25265.1 - 1.8e-08 33.7 0.0 7.9e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGG25265.1 - 2e-06 27.5 0.1 0.00056 19.7 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EGG25265.1 - 2.8e-06 27.7 0.0 4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGG25265.1 - 6.3e-06 25.4 0.0 0.004 16.6 0.0 2.1 2 0 0 2 2 2 2 EF hand Ribosomal_L14 PF00238.19 EGG25266.1 - 4.2e-31 107.6 0.2 4.7e-31 107.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ank_2 PF12796.7 EGG25269.1 - 3.5e-06 27.5 0.1 0.023 15.3 0.0 4.8 2 1 3 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG25269.1 - 1.1e-05 25.8 0.2 0.69 10.6 0.0 5.4 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG25269.1 - 0.0022 18.3 0.1 4.5 8.2 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EGG25269.1 - 0.048 14.0 0.0 0.52 10.7 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Methyltransf_12 PF08242.12 EGG25270.1 - 4.2 8.2 5.4 1.9 9.3 0.3 2.8 3 1 0 3 3 3 0 Methyltransferase domain Ric8 PF10165.9 EGG25271.1 - 1e-23 84.1 0.1 3.7e-23 82.3 0.1 1.8 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn LAGLIDADG_1 PF00961.19 EGG25271.1 - 0.017 16.1 0.1 0.039 14.9 0.1 1.6 1 0 0 1 1 1 0 LAGLIDADG endonuclease DNA_topoisoIV PF00521.20 EGG25272.1 - 1.1e-115 386.9 0.5 1.7e-115 386.4 0.5 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EGG25272.1 - 6.5e-42 142.8 3.8 6.5e-42 142.8 3.8 2.8 4 0 0 4 4 4 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EGG25272.1 - 3.3e-23 82.0 0.2 9.7e-23 80.5 0.2 1.8 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EGG25272.1 - 7.1e-10 39.4 0.0 2.1e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EGG25272.1 - 3.7e-09 36.8 0.0 1.2e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Methyltransf_16 PF10294.9 EGG25273.1 - 3.9e-32 111.4 0.1 1.3e-30 106.5 0.0 2.2 2 0 0 2 2 2 1 Lysine methyltransferase MTS PF05175.14 EGG25273.1 - 0.0014 18.2 0.1 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Tim54 PF11711.8 EGG25273.1 - 0.0036 16.2 7.1 0.0053 15.6 7.1 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Methyltransf_23 PF13489.6 EGG25273.1 - 0.033 14.0 0.0 0.063 13.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain LMBR1 PF04791.16 EGG25273.1 - 0.061 12.2 0.2 0.071 12.0 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HNF-1_N PF04814.13 EGG25273.1 - 0.066 13.8 8.6 0.12 12.9 8.6 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus PA26 PF04636.13 EGG25273.1 - 0.27 10.1 7.6 0.38 9.6 7.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SLC12 PF03522.15 EGG25273.1 - 0.31 10.0 8.5 0.46 9.5 8.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 EGG25273.1 - 0.38 9.5 9.0 0.57 8.9 9.0 1.2 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 EGG25273.1 - 1.3 8.5 8.3 2.2 7.7 8.3 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.22 EGG25273.1 - 1.5 8.0 6.4 2.1 7.5 6.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Membralin PF09746.9 EGG25273.1 - 6.5 5.7 7.6 9.3 5.2 7.6 1.2 1 0 0 1 1 1 0 Tumour-associated protein Ribosomal_L18 PF17135.4 EGG25274.1 - 1.7e-72 242.8 5.1 2.3e-72 242.3 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Isy1 PF06246.12 EGG25274.1 - 0.0021 17.7 0.1 0.0027 17.3 0.1 1.2 1 0 0 1 1 1 1 Isy1-like splicing family Ribosomal_L27A PF00828.19 EGG25274.1 - 0.0043 17.7 2.8 0.015 16.0 0.2 2.3 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Folate_carrier PF01770.18 EGG25275.1 - 8.7e-32 110.4 29.0 9.3e-18 64.2 9.0 4.4 3 2 1 4 4 4 2 Reduced folate carrier MFS_1 PF07690.16 EGG25275.1 - 0.00015 20.8 33.5 0.0027 16.7 8.6 3.8 3 2 2 5 5 5 2 Major Facilitator Superfamily Herpes_LMP1 PF05297.11 EGG25275.1 - 0.058 12.6 5.6 0.13 11.4 5.6 1.6 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) EphA2_TM PF14575.6 EGG25275.1 - 2.9 8.8 6.9 1.6e+02 3.3 0.0 4.4 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Ninjurin PF04923.12 EGG25275.1 - 7.9 6.5 10.7 0.21 11.5 0.4 3.5 1 1 3 4 4 4 0 Ninjurin ApoO PF09769.9 EGG25276.1 - 0.048 13.6 0.7 0.063 13.2 0.7 1.2 1 0 0 1 1 1 0 Apolipoprotein O PRTase_1 PF11202.8 EGG25276.1 - 0.11 11.7 1.6 0.15 11.3 1.6 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) MRP-S32 PF10210.9 EGG25276.1 - 1 10.0 11.4 1.9 9.1 1.8 2.4 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S32 DEAD PF00270.29 EGG25277.1 - 5.9e-16 58.7 0.0 1.7e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGG25277.1 - 3.8e-13 49.8 0.0 3.8e-13 49.8 0.0 4.9 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGG25277.1 - 3.6e-06 27.3 3.4 1.1e-05 25.8 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain T2SSE PF00437.20 EGG25277.1 - 0.074 12.1 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Ank_2 PF12796.7 EGG25278.1 - 1.1e-09 38.8 0.2 1.6e-05 25.4 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG25278.1 - 2.4e-08 34.4 0.4 0.014 15.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGG25278.1 - 0.018 15.4 0.1 27 5.2 0.0 3.5 1 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGG25278.1 - 0.047 14.2 0.0 2.4e+02 2.9 0.0 4.6 4 0 0 4 4 4 0 Ankyrin repeat DUF4596 PF15363.6 EGG25281.1 - 0.051 13.8 0.1 0.073 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) DUF4048 PF13257.6 EGG25283.1 - 0.001 19.0 4.0 0.0016 18.3 4.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4048) Menin PF05053.13 EGG25283.1 - 0.026 12.9 11.5 0.04 12.3 11.5 1.3 1 0 0 1 1 1 0 Menin 4_1_CTD PF05902.13 EGG25285.1 - 0.00029 20.9 9.2 0.00029 20.9 9.2 1.1 1 0 0 1 1 1 1 4.1 protein C-terminal domain (CTD) DUF3439 PF11921.8 EGG25285.1 - 0.012 15.5 7.8 0.012 15.5 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGG25285.1 - 0.084 12.9 10.3 0.081 12.9 10.3 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Fibrinogen_aC PF12160.8 EGG25285.1 - 0.098 12.5 6.8 0.14 12.0 6.8 1.2 1 0 0 1 1 1 0 Fibrinogen alpha C domain SSP160 PF06933.11 EGG25285.1 - 1 7.5 10.0 1 7.5 10.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 EGG25285.1 - 3.5 5.5 9.8 3.1 5.7 9.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNase_T PF00929.24 EGG25286.1 - 1.2e-08 35.7 0.1 2.4e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Exonuclease Myosin_head PF00063.21 EGG25290.1 - 2.8e-269 895.0 6.9 3.4e-269 894.7 6.9 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGG25290.1 - 2.1e-40 138.4 0.5 3.6e-40 137.6 0.5 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 EGG25290.1 - 0.00015 21.3 12.0 0.059 13.2 1.1 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_16 PF13191.6 EGG25290.1 - 0.0048 17.3 0.0 0.016 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGG25290.1 - 0.013 15.8 0.1 0.044 14.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGG25290.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 EGG25290.1 - 0.037 13.3 0.0 0.091 12.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Pkinase PF00069.25 EGG25291.1 - 3.8e-85 285.4 4.4 2.2e-42 145.3 0.1 3.9 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGG25291.1 - 2e-43 148.5 1.9 4.9e-14 52.2 0.2 4.5 4 0 0 4 4 4 4 Protein tyrosine kinase tRNA-synt_His PF13393.6 EGG25291.1 - 4.1e-20 72.3 0.0 7.5e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.7 EGG25291.1 - 4.2e-15 56.0 0.1 4.2e-15 56.0 0.1 3.6 4 0 0 4 4 2 1 Anticodon binding domain of tRNAs RWD PF05773.22 EGG25291.1 - 8.3e-15 55.1 0.5 8.3e-15 55.1 0.5 3.5 3 1 0 3 3 2 1 RWD domain HGTP_anticodon PF03129.20 EGG25291.1 - 3.6e-06 27.0 0.0 9.3e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain DUF2457 PF10446.9 EGG25291.1 - 7.7e-06 25.3 26.5 7.7e-06 25.3 26.5 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Kdo PF06293.14 EGG25291.1 - 0.0012 18.2 0.0 0.32 10.3 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGG25291.1 - 0.0059 16.6 0.0 0.032 14.1 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGG25291.1 - 0.029 14.0 0.3 12 5.5 0.0 3.4 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 TFIIF_alpha PF05793.12 EGG25291.1 - 0.92 8.0 32.0 0.0078 14.9 20.4 2.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 EGG25291.1 - 1.4 7.0 31.7 0.023 13.0 21.5 2.2 2 0 0 2 2 2 0 Nop14-like family CPSF100_C PF13299.6 EGG25291.1 - 2.3 8.4 11.0 8.3 6.6 11.0 1.9 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 EGG25291.1 - 6.2 5.0 28.1 1.4 7.2 19.7 2.2 2 0 0 2 2 2 0 CDC45-like protein YL1 PF05764.13 EGG25291.1 - 8.8 6.4 22.1 0.59 10.2 14.0 2.6 2 0 0 2 2 2 0 YL1 nuclear protein Pilin PF00114.19 EGG25292.1 - 0.14 13.1 1.3 0.42 11.6 0.4 2.1 1 1 1 2 2 2 0 Pilin (bacterial filament) Ras PF00071.22 EGG25293.1 - 4.9e-47 159.5 0.0 5.7e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG25293.1 - 2.4e-19 69.7 0.0 3.6e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG25293.1 - 2.1e-09 37.1 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGG25293.1 - 5.2e-06 26.5 0.0 0.024 14.6 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGG25293.1 - 1.1e-05 25.0 0.0 3e-05 23.6 0.0 1.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 EGG25293.1 - 0.00021 20.9 0.1 0.0023 17.5 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region TniB PF05621.11 EGG25293.1 - 0.014 14.8 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein Gtr1_RagA PF04670.12 EGG25293.1 - 0.06 12.7 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TraB PF01963.17 EGG25294.1 - 1.9e-23 83.7 0.1 1.1e-15 58.3 0.0 2.6 2 0 0 2 2 2 2 TraB family HMD PF03201.16 EGG25294.1 - 0.071 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase rhaM PF05336.13 EGG25295.1 - 2.3e-29 101.6 0.8 2.5e-29 101.5 0.8 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase IL32 PF15225.6 EGG25295.1 - 0.0047 17.3 0.0 0.0067 16.8 0.0 1.3 1 0 0 1 1 1 1 Interleukin 32 MSC PF09402.10 EGG25296.1 - 1.3e-22 80.7 0.0 1.3e-22 80.7 0.0 4.0 3 1 0 3 3 3 1 Man1-Src1p-C-terminal domain RGS PF00615.19 EGG25296.1 - 6.5e-22 78.0 6.2 6.5e-22 78.0 6.2 3.3 3 0 0 3 3 3 1 Regulator of G protein signaling domain LRR_8 PF13855.6 EGG25296.1 - 1.7e-13 50.1 15.8 7.5e-09 35.2 5.8 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EGG25296.1 - 4.8e-08 33.2 27.4 4.4e-06 26.9 1.2 4.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGG25296.1 - 0.00033 20.2 8.5 0.049 13.1 1.8 3.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EGG25296.1 - 0.075 13.6 7.3 15 6.6 0.4 5.4 4 0 0 4 4 4 0 Leucine Rich Repeat AT_hook PF02178.19 EGG25297.1 - 2 8.6 8.4 0.27 11.2 3.4 2.5 2 0 0 2 2 2 0 AT hook motif tRNA-synt_1c PF00749.21 EGG25298.1 - 1e-113 379.4 0.1 1.5e-113 378.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGG25298.1 - 1.5e-50 171.5 0.0 4.4e-50 170.0 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 EGG25298.1 - 2.8e-46 157.5 0.3 5.4e-46 156.5 0.3 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 EGG25298.1 - 1.8e-11 44.8 3.8 5.2e-11 43.3 3.8 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 MAGE_N PF12440.8 EGG25298.1 - 0.12 13.1 0.9 0.22 12.2 0.9 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Pet191_N PF10203.9 EGG25299.1 - 0.00074 19.8 0.9 0.00074 19.8 0.9 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein PET191 RNA_POL_M_15KD PF02150.16 EGG25300.1 - 3.1e-09 36.5 2.6 3.1e-09 36.5 2.6 2.2 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 EGG25300.1 - 0.011 15.6 4.1 0.13 12.2 0.1 3.2 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) ArgoN PF16486.5 EGG25301.1 - 0.035 14.7 0.0 0.097 13.3 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of argonaute SprT-like PF10263.9 EGG25301.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 SprT-like family RRP7 PF12923.7 EGG25301.1 - 1.8 8.7 6.1 0.42 10.7 0.1 2.7 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain SSP160 PF06933.11 EGG25301.1 - 6.8 4.8 12.9 9.7 4.3 12.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DIL PF01843.19 EGG25302.1 - 1.6e-15 57.3 2.0 5e-15 55.7 2.0 1.9 1 0 0 1 1 1 1 DIL domain NT-C2 PF10358.9 EGG25302.1 - 9.6e-12 44.8 1.5 2.1e-11 43.7 1.5 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Carboxyl_trans PF01039.22 EGG25303.1 - 0.072 11.7 0.4 0.14 10.8 0.4 1.4 1 0 0 1 1 1 0 Carboxyl transferase domain SOG2 PF10428.9 EGG25303.1 - 8.3 5.5 12.8 11 5.0 12.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Nup96 PF12110.8 EGG25304.1 - 3.4e-66 223.4 0.6 7.3e-66 222.2 0.6 1.6 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EGG25304.1 - 3.5e-45 153.8 0.0 3.5e-45 153.8 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EGG25304.1 - 4.3e-22 78.8 284.9 9.4e-11 42.4 29.4 11.0 3 2 5 9 9 9 5 Nucleoporin FG repeat region Csm1_B PF18211.1 EGG25304.1 - 0.0023 17.7 0.1 0.0091 15.8 0.1 2.0 1 0 0 1 1 1 1 Csm1 subunit domain B TLD PF07534.16 EGG25305.1 - 6e-36 123.7 1.6 9.1e-36 123.1 1.6 1.3 1 0 0 1 1 1 1 TLD TMEM171 PF15471.6 EGG25305.1 - 0.0027 16.7 0.5 0.0037 16.3 0.5 1.1 1 0 0 1 1 1 1 Transmembrane protein family 171 Thioredoxin PF00085.20 EGG25306.1 - 3.9e-55 184.2 2.9 7.4e-26 90.1 0.0 3.6 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 EGG25306.1 - 2.9e-36 125.1 8.0 2.5e-30 105.7 1.7 3.6 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGG25306.1 - 8.5e-11 41.9 0.1 0.00045 20.3 0.2 3.6 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGG25306.1 - 3e-10 40.5 0.3 0.00069 20.0 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EGG25306.1 - 1.3e-09 37.9 1.8 0.0011 18.4 0.0 3.1 3 1 1 4 4 4 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 EGG25306.1 - 1.3e-08 34.4 2.0 1.3e-08 34.4 2.0 1.5 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_8 PF13905.6 EGG25306.1 - 5.3e-07 29.9 4.5 0.058 13.7 0.0 4.6 3 2 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 EGG25306.1 - 2.6e-05 24.1 0.8 0.35 10.8 0.0 3.2 2 1 0 3 3 3 2 AhpC/TSA family TraF PF13728.6 EGG25306.1 - 0.00072 19.5 4.7 0.15 11.9 0.0 2.9 3 0 0 3 3 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EGG25306.1 - 0.0018 18.0 0.2 0.068 12.9 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin Glutaredoxin PF00462.24 EGG25306.1 - 0.0029 17.8 0.1 3.1 8.1 0.0 2.8 2 0 0 2 2 2 2 Glutaredoxin Ribosomal_L24e PF01246.20 EGG25307.1 - 2.4e-32 110.9 5.3 4.8e-32 110.0 5.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e DUF3268 PF11672.8 EGG25307.1 - 0.05 13.9 0.4 0.094 13.0 0.4 1.5 1 0 0 1 1 1 0 zinc-finger-containing domain DUF3430 PF11912.8 EGG25308.1 - 6.1e-14 52.6 27.0 6.1e-14 52.6 27.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3430) DUF2140 PF09911.9 EGG25308.1 - 0.02 14.4 0.1 0.03 13.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) GRP PF07172.11 EGG25308.1 - 0.037 14.7 0.0 0.063 14.0 0.0 1.4 1 0 0 1 1 1 0 Glycine rich protein family DUF4834 PF16118.5 EGG25308.1 - 0.051 14.5 0.6 0.11 13.4 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Rgp1 PF08737.10 EGG25310.1 - 1.1e-37 130.2 19.8 1.1e-22 80.8 0.5 3.1 2 1 1 3 3 3 2 Rgp1 Arrestin_N PF00339.29 EGG25310.1 - 0.022 14.8 1.1 1.3 9.1 0.1 3.3 3 1 1 4 4 4 0 Arrestin (or S-antigen), N-terminal domain DGF-1_C PF11040.8 EGG25310.1 - 6.8 6.8 5.9 9.8 6.3 4.4 2.1 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF444 PF04285.12 EGG25311.1 - 4.5e-05 22.7 0.2 0.25 10.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF444) VWA_2 PF13519.6 EGG25311.1 - 0.0035 18.0 0.2 3.4 8.4 0.0 3.4 3 0 0 3 3 3 2 von Willebrand factor type A domain CarboxypepD_reg PF13620.6 EGG25311.1 - 0.0073 16.5 0.2 0.1 12.9 0.0 3.0 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain MatP_C PF17414.2 EGG25311.1 - 0.012 15.8 2.1 3.7 7.8 0.1 3.2 3 0 0 3 3 3 0 MatP C-terminal ribbon-helix-helix domain VWA_CoxE PF05762.14 EGG25311.1 - 0.016 14.6 0.8 5.1 6.4 0.1 2.4 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein PhoQ_Sensor PF08918.10 EGG25311.1 - 0.027 14.3 0.7 5.4 6.8 0.1 2.7 2 0 0 2 2 2 0 PhoQ Sensor DUF3251 PF11622.8 EGG25311.1 - 0.093 12.4 1.4 1.8 8.2 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3251) zf-trcl PF13451.6 EGG25312.1 - 3.1e-06 27.0 1.4 6.8e-06 25.9 1.4 1.5 1 0 0 1 1 1 1 Probable zinc-ribbon domain SlyX PF04102.12 EGG25312.1 - 0.34 11.6 11.4 0.73 10.5 11.4 1.5 1 0 0 1 1 1 0 SlyX DivIC PF04977.15 EGG25312.1 - 0.34 10.7 6.1 0.69 9.7 6.1 1.5 1 0 0 1 1 1 0 Septum formation initiator COQ7 PF03232.13 EGG25314.1 - 3.4e-71 238.5 0.1 4.2e-71 238.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EGG25314.1 - 2e-05 25.0 0.1 4.9e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Rubrerythrin Ferritin_2 PF13668.6 EGG25314.1 - 0.021 15.0 0.7 0.39 10.9 0.1 2.2 1 1 1 2 2 2 0 Ferritin-like domain Phenol_Hydrox PF02332.18 EGG25314.1 - 0.068 12.7 0.1 0.69 9.4 0.1 2.1 2 0 0 2 2 2 0 Methane/Phenol/Toluene Hydroxylase Metal_hydrol PF10118.9 EGG25314.1 - 0.082 12.6 3.7 0.55 9.9 1.9 2.1 1 1 1 2 2 2 0 Predicted metal-dependent hydrolase BHD_3 PF10405.9 EGG25315.1 - 1.3e-22 80.0 0.0 2.9e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 EGG25315.1 - 4.2e-18 65.4 4.7 4.2e-18 65.4 4.7 3.4 3 1 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 EGG25315.1 - 2.4e-12 46.5 0.1 1.3e-11 44.1 0.1 2.4 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EGG25315.1 - 0.0014 19.5 3.5 0.0014 19.5 3.5 4.9 3 2 0 3 3 3 1 Rad4 beta-hairpin domain 2 Mtc PF03820.17 EGG25316.1 - 1.3e-115 385.8 1.0 1.9e-115 385.2 1.0 1.2 1 0 0 1 1 1 1 Tricarboxylate carrier SWIM PF04434.17 EGG25317.1 - 0.088 12.5 1.3 0.18 11.5 1.3 1.5 1 0 0 1 1 1 0 SWIM zinc finger Aminotran_1_2 PF00155.21 EGG25318.1 - 2.8e-18 66.2 0.0 3.5e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGG25318.1 - 0.00013 20.8 0.0 0.00017 20.5 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase HOIP-UBA PF16678.5 EGG25318.1 - 0.095 12.7 0.1 3.7 7.5 0.1 2.2 2 0 0 2 2 2 0 HOIP UBA domain pair DUF3258 PF11646.8 EGG25318.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF3258 DUF2169 PF09937.9 EGG25319.1 - 0.15 11.5 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) SNF2_N PF00176.23 EGG25320.1 - 2.1e-70 237.2 0.3 7.1e-70 235.5 0.3 1.9 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 EGG25320.1 - 6.9e-07 29.5 6.4 6.9e-07 29.5 6.4 3.1 3 0 0 3 3 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGG25320.1 - 2.6e-06 27.2 6.5 2.6e-06 27.2 6.5 3.6 5 1 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGG25320.1 - 8e-06 25.7 6.6 8e-06 25.7 6.6 2.8 2 0 0 2 2 1 1 zinc-RING finger domain Helicase_C PF00271.31 EGG25320.1 - 4.4e-05 23.8 0.0 0.00026 21.3 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 EGG25320.1 - 8.7e-05 22.5 3.5 8.7e-05 22.5 3.5 2.3 2 0 0 2 2 1 1 RING-type zinc-finger PHD PF00628.29 EGG25320.1 - 0.00015 21.6 8.6 0.00015 21.6 8.6 4.2 4 0 0 4 4 3 1 PHD-finger zf-C3HC4 PF00097.25 EGG25320.1 - 0.00035 20.4 6.9 0.00035 20.4 6.9 3.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGG25320.1 - 0.00053 19.8 5.5 0.0024 17.7 5.5 2.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGG25320.1 - 0.00055 19.7 7.3 0.0024 17.7 7.3 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_10 PF13374.6 EGG25320.1 - 0.026 14.4 0.1 0.081 12.8 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 EGG25320.1 - 0.055 13.8 3.7 0.32 11.3 3.7 2.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain Lumazine_bd_2 PF12893.7 EGG25320.1 - 0.074 13.7 1.5 0.73 10.5 0.0 3.0 3 0 0 3 3 2 0 Putative lumazine-binding zf-CW PF07496.15 EGG25320.1 - 0.16 12.0 8.8 0.1 12.6 5.7 2.5 2 0 0 2 2 1 0 CW-type Zinc Finger zf-ANAPC11 PF12861.7 EGG25320.1 - 3 7.9 9.9 0.45 10.6 1.7 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGG25320.1 - 6.7 6.6 14.1 0.037 13.8 4.8 2.1 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain Proteasom_Rpn13 PF04683.13 EGG25321.1 - 2.9e-08 34.1 0.0 2.4e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 Proteasome complex subunit Rpn13 ubiquitin receptor TRM13 PF05206.14 EGG25321.1 - 0.024 14.2 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase TRM13 VWA_2 PF13519.6 EGG25321.1 - 0.046 14.4 0.0 0.12 13.0 0.0 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain COX16 PF14138.6 EGG25323.1 - 4.9e-10 39.8 0.3 3.9e-09 36.9 0.3 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Pkinase PF00069.25 EGG25324.1 - 5.7e-56 189.8 0.5 1.3e-55 188.6 0.5 1.6 1 0 0 1 1 1 1 Protein kinase domain Peptidase_M24 PF00557.24 EGG25324.1 - 4.8e-55 186.5 0.1 1.1e-54 185.3 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 Pkinase_Tyr PF07714.17 EGG25324.1 - 1.2e-27 96.9 0.1 1.9e-27 96.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGG25324.1 - 8.9e-09 35.1 0.0 3.7e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Mt_ATP_synt PF15704.5 EGG25325.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit Pox_MCEL PF03291.16 EGG25326.1 - 1.9e-73 247.5 3.7 3.8e-73 246.5 3.7 1.5 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EGG25326.1 - 1.2e-06 29.1 0.0 3.7e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG25326.1 - 6.7e-05 23.6 0.0 6.7e-05 23.6 0.0 4.2 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGG25326.1 - 8.6e-05 23.1 0.0 0.00024 21.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EGG25326.1 - 0.00071 18.9 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family EF-hand_5 PF13202.6 EGG25326.1 - 0.0031 16.9 0.5 0.95 9.1 0.1 3.0 2 0 0 2 2 2 2 EF hand Clat_adaptor_s PF01217.20 EGG25327.1 - 6.5e-39 133.1 8.9 6.2e-37 126.7 8.9 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Homeobox_KN PF05920.11 EGG25328.1 - 2e-17 62.8 1.7 4.6e-17 61.6 1.7 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EGG25328.1 - 6.1e-08 32.4 0.2 2e-07 30.8 0.2 1.9 1 0 0 1 1 1 1 Homeodomain DUF1793 PF08760.11 EGG25328.1 - 0.077 13.4 1.2 4.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1793) DUF5102 PF17104.5 EGG25329.1 - 0.0042 17.2 11.0 0.0042 17.2 11.0 10.5 3 3 7 10 10 10 2 Domain of unknown function (DUF5102) 2OG-FeII_Oxy_3 PF13640.6 EGG25330.1 - 2.8e-15 57.0 0.0 4.1e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGG25330.1 - 0.00061 20.2 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 EGG25330.1 - 0.097 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein ATP-synt_J PF04911.12 EGG25331.1 - 0.016 14.8 0.4 0.016 14.8 0.4 1.5 2 0 0 2 2 2 0 ATP synthase j chain SNARE PF05739.19 EGG25332.1 - 2.2e-10 40.3 0.2 2.2e-10 40.3 0.2 1.7 2 0 0 2 2 2 1 SNARE domain NINJA_B PF16136.5 EGG25332.1 - 0.11 12.9 4.1 0.23 11.8 4.1 1.5 1 0 0 1 1 1 0 Putative nuclear localisation signal RAMP4 PF06624.12 EGG25333.1 - 4.5e-07 29.8 0.1 4.5e-07 29.8 0.1 1.9 2 0 0 2 2 2 1 Ribosome associated membrane protein RAMP4 Cadherin_tail PF15974.5 EGG25333.1 - 0.041 14.2 2.0 0.07 13.5 0.1 1.9 2 0 0 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Mit_KHE1 PF10173.9 EGG25334.1 - 6.3e-39 134.0 0.8 6.3e-39 134.0 0.8 2.1 2 1 0 2 2 2 1 Mitochondrial K+-H+ exchange-related RNB PF00773.19 EGG25336.1 - 1.9e-33 116.2 0.2 4.3e-32 111.7 0.2 2.6 1 1 0 1 1 1 1 RNB domain AAA_11 PF13086.6 EGG25336.1 - 2.3e-22 80.1 0.0 1.8e-10 41.1 0.0 2.9 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 EGG25336.1 - 6.9e-13 48.7 0.5 6.9e-13 48.7 0.5 2.0 2 0 0 2 2 2 1 AAA domain DUF5599 PF18141.1 EGG25336.1 - 0.0019 18.4 0.1 0.0073 16.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5599) AAA_23 PF13476.6 EGG25336.1 - 0.0066 17.0 0.0 0.035 14.6 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGG25336.1 - 0.014 15.1 0.5 0.056 13.2 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 EGG25336.1 - 0.026 14.4 0.2 0.71 9.8 0.1 3.2 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.6 EGG25336.1 - 0.051 13.8 0.1 0.4 11.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGG25336.1 - 0.061 13.2 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase DEAD PF00270.29 EGG25336.1 - 0.091 12.5 0.4 0.59 9.9 0.1 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EGG25336.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 EGG25337.1 - 2.2e-64 217.4 1.0 1.8e-63 214.4 1.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG25337.1 - 6.7e-29 101.0 2.9 1.6e-20 73.5 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EGG25337.1 - 3.6e-05 24.4 0.9 0.00035 21.2 0.2 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGG25337.1 - 0.00016 20.7 0.4 0.00027 20.0 0.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGG25337.1 - 0.0016 18.4 0.1 0.15 12.0 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGG25337.1 - 0.0027 16.8 0.0 0.0065 15.6 0.0 1.6 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EGG25337.1 - 0.0042 16.4 0.1 0.095 12.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGG25337.1 - 0.0071 15.7 0.1 0.0071 15.7 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3987 PF13148.6 EGG25337.1 - 0.047 12.7 0.0 0.047 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) CENP-B_dimeris PF09026.10 EGG25337.1 - 1.8 9.0 8.2 3.6 8.0 8.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ACOX PF01756.19 EGG25340.1 - 1.7e-17 63.6 0.0 2.9e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGG25340.1 - 1.8e-16 60.1 0.1 3.1e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EGG25340.1 - 1.5e-10 41.7 0.1 3.5e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EGG25340.1 - 1.6e-06 28.4 0.0 3.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGG25340.1 - 0.14 12.8 0.0 0.31 11.7 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Ank_2 PF12796.7 EGG25341.1 - 3.6e-08 33.9 0.4 0.07 13.7 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Hep_59 PF07052.11 EGG25341.1 - 0.0025 18.6 0.9 0.005 17.6 0.9 1.4 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 Orf78 PF06024.12 EGG25341.1 - 0.066 13.5 3.4 0.17 12.2 3.4 1.6 1 0 0 1 1 1 0 Orf78 (ac78) PRP1_N PF06424.12 EGG25341.1 - 0.1 13.0 3.1 0.18 12.2 3.1 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal TRM13 PF05206.14 EGG25341.1 - 0.39 10.2 4.5 0.36 10.3 1.4 2.1 2 0 0 2 2 2 0 Methyltransferase TRM13 Secretin_N_2 PF07655.13 EGG25341.1 - 2.7 8.6 17.4 0.46 11.1 13.1 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4834 PF16118.5 EGG25341.1 - 7.3 7.6 6.3 17 6.5 6.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Carboxyl_trans PF01039.22 EGG25342.1 - 3.2e-162 540.6 0.0 4.6e-162 540.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 EGG25342.1 - 5.1e-127 425.0 1.5 2e-86 290.8 0.4 2.1 1 1 1 2 2 2 2 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 EGG25342.1 - 2.8e-52 177.3 0.0 5.1e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGG25342.1 - 1.6e-29 102.7 0.8 4e-29 101.4 0.1 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGG25342.1 - 1.6e-19 70.0 0.0 5.4e-19 68.3 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGG25342.1 - 3.7e-11 42.7 0.0 8.1e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 EGG25342.1 - 4.1e-08 33.0 0.1 9.4e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGG25342.1 - 2.7e-06 27.1 0.0 5.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EGG25342.1 - 2.1e-05 24.6 0.2 0.00013 22.1 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain IL31 PF15209.6 EGG25342.1 - 0.0088 15.8 1.2 0.22 11.3 0.4 2.8 1 1 0 2 2 2 1 Interleukin 31 ATPgrasp_ST PF14397.6 EGG25342.1 - 0.65 9.2 4.7 5.4 6.2 0.0 2.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Ank_4 PF13637.6 EGG25343.1 - 3.9e-05 24.1 0.5 0.023 15.3 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG25343.1 - 0.00048 20.7 0.2 0.0029 18.2 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) NOA36 PF06524.12 EGG25343.1 - 0.0025 17.2 8.3 0.0042 16.5 8.3 1.3 1 0 0 1 1 1 1 NOA36 protein HTH_5 PF01022.20 EGG25343.1 - 0.089 12.7 0.3 0.27 11.1 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family RNase_H2_suC PF08615.11 EGG25343.1 - 0.67 10.1 3.4 1.5 9.0 3.4 1.5 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FAM176 PF14851.6 EGG25343.1 - 5.8 6.6 9.6 12 5.5 9.6 1.5 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 EGG25343.1 - 8.3 4.5 19.9 12 4.0 19.9 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 EGG25343.1 - 8.4 6.4 25.7 16 5.5 25.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Presenilin PF01080.17 EGG25343.1 - 8.8 5.0 5.6 15 4.2 5.6 1.3 1 0 0 1 1 1 0 Presenilin Ank_4 PF13637.6 EGG25344.1 - 5.5e-05 23.6 0.3 0.04 14.5 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGG25344.1 - 0.00014 22.4 0.4 0.0044 17.6 0.1 3.1 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGG25344.1 - 0.042 14.2 0.0 2.8 8.4 0.1 3.0 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Merozoite_SPAM PF07133.11 EGG25345.1 - 0.015 15.3 30.1 0.024 14.7 30.1 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2052 PF09747.9 EGG25345.1 - 0.028 14.5 19.2 0.03 14.5 19.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RRN3 PF05327.11 EGG25345.1 - 0.29 9.6 10.2 0.25 9.8 10.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.12 EGG25345.1 - 0.42 10.0 20.2 0.49 9.7 20.2 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PI3K_1B_p101 PF10486.9 EGG25345.1 - 1.5 6.5 9.2 1.6 6.4 9.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 EGG25345.1 - 1.7 6.9 23.6 1.8 6.8 23.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 EGG25345.1 - 2 7.3 10.4 2.2 7.2 10.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 EGG25345.1 - 2.3 7.4 12.2 2.6 7.2 12.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RR_TM4-6 PF06459.12 EGG25345.1 - 2.4 7.9 22.7 2.5 7.9 22.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 EGG25345.1 - 2.9 8.3 16.7 3.7 8.0 16.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 EGG25345.1 - 3.6 7.8 15.6 4 7.6 15.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal VIR_N PF15912.5 EGG25345.1 - 4.6 6.7 15.0 5.2 6.6 15.0 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Paf1 PF03985.13 EGG25345.1 - 4.8 6.1 25.7 5.4 5.9 25.7 1.1 1 0 0 1 1 1 0 Paf1 PTPRCAP PF15713.5 EGG25345.1 - 4.8 7.5 20.2 5.6 7.3 20.2 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DNA_pol_phi PF04931.13 EGG25345.1 - 4.9 5.1 24.2 5.5 5.0 24.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Roughex PF06020.11 EGG25345.1 - 5.3 6.1 12.8 5.7 5.9 12.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SLC12 PF03522.15 EGG25345.1 - 5.7 5.8 13.3 5.5 5.9 13.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DDHD PF02862.17 EGG25345.1 - 7.1 6.7 9.0 7.9 6.6 9.0 1.2 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 EGG25345.1 - 8.5 5.0 16.1 8.7 5.0 16.1 1.0 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 EGG25345.1 - 9.2 6.0 10.3 10 5.8 10.3 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Hid1 PF12722.7 EGG25345.1 - 9.9 4.1 13.1 10 4.1 13.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ank_2 PF12796.7 EGG25346.1 - 0.0015 19.1 0.2 0.017 15.7 0.0 2.8 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGG25346.1 - 0.0022 18.5 1.0 3.1 8.5 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeats (many copies) CDC45 PF02724.14 EGG25346.1 - 0.53 8.5 24.7 0.77 8.0 24.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 EGG25346.1 - 0.58 9.1 5.4 1.1 8.1 5.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GAGA_bind PF06217.12 EGG25346.1 - 0.83 9.9 9.2 1.2 9.3 9.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Nop14 PF04147.12 EGG25346.1 - 0.85 7.7 27.9 1.2 7.3 27.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2052 PF09747.9 EGG25346.1 - 1.3 9.1 23.7 5.8 7.0 24.2 1.8 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Sporozoite_P67 PF05642.11 EGG25346.1 - 1.5 6.9 15.4 2.3 6.2 15.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC27 PF09507.10 EGG25346.1 - 7.5 5.8 30.8 12 5.1 30.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Presenilin PF01080.17 EGG25346.1 - 7.9 5.1 17.0 12 4.5 17.0 1.3 1 0 0 1 1 1 0 Presenilin AAA_13 PF13166.6 EGG25347.1 - 0.0015 17.3 36.7 0.0015 17.3 36.7 6.2 2 1 3 6 6 6 2 AAA domain BRE1 PF08647.11 EGG25347.1 - 0.003 17.6 14.3 0.003 17.6 14.3 11.4 5 3 7 12 12 12 2 BRE1 E3 ubiquitin ligase NRDE-2 PF08424.10 EGG25348.1 - 4.4e-83 279.1 36.1 2.1e-82 276.8 25.0 5.0 4 1 0 4 4 4 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EGG25348.1 - 3.6e-05 24.2 1.9 54 5.0 0.0 6.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGG25348.1 - 0.00011 22.6 0.5 3.3 8.3 0.1 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGG25348.1 - 0.00053 20.2 0.0 0.022 15.0 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGG25348.1 - 0.012 15.9 0.7 4.4 7.9 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGG25348.1 - 0.17 12.1 0.1 16 5.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SAP PF02037.27 EGG25349.1 - 0.00054 19.7 1.3 0.0072 16.1 0.0 3.2 3 0 0 3 3 3 1 SAP domain DUF4518 PF15008.6 EGG25349.1 - 0.024 13.8 0.6 0.058 12.6 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) SEP PF08059.13 EGG25349.1 - 0.14 12.7 1.8 0.5 11.0 0.1 2.6 3 0 0 3 3 3 0 SEP domain VEFS-Box PF09733.9 EGG25349.1 - 0.86 9.4 4.2 1.8 8.4 4.2 1.6 1 0 0 1 1 1 0 VEFS-Box of polycomb protein SSP160 PF06933.11 EGG25349.1 - 1.6 6.8 3.9 2.5 6.2 3.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 EGG25349.1 - 9.1 4.1 17.3 19 3.1 17.3 1.5 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SPRY PF00622.28 EGG25350.1 - 1.3e-11 44.6 0.2 1.3e-11 44.6 0.2 2.7 2 1 1 3 3 3 1 SPRY domain SUIM_assoc PF16619.5 EGG25350.1 - 0.00027 20.9 0.4 0.00027 20.9 0.4 5.7 4 2 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 CENP-B_dimeris PF09026.10 EGG25350.1 - 0.063 13.7 6.5 0.56 10.6 7.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain E6 PF00518.17 EGG25351.1 - 0.0084 16.5 0.8 0.017 15.5 0.8 1.5 1 0 0 1 1 1 1 Early Protein (E6) ABC2_membrane_3 PF12698.7 EGG25352.1 - 2.5e-36 125.5 33.0 2.5e-36 125.5 33.0 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 EGG25352.1 - 3.4e-28 98.5 31.4 5.3e-28 97.9 16.0 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGG25352.1 - 1.1e-20 74.5 0.1 1.1e-19 71.3 0.0 2.3 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_2 PF12679.7 EGG25352.1 - 7.8e-13 48.4 13.7 1.3e-12 47.6 13.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGG25352.1 - 1.5e-06 28.3 2.1 9e-06 25.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF4293 PF14126.6 EGG25352.1 - 0.064 13.5 9.6 0.044 14.0 6.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) PDR_CDR PF06422.12 EGG25352.1 - 0.13 12.2 1.5 0.24 11.3 0.5 2.0 2 0 0 2 2 2 0 CDR ABC transporter CcmB PF03379.13 EGG25352.1 - 0.14 11.6 9.2 0.039 13.4 5.8 1.8 2 0 0 2 2 2 0 CcmB protein IRK_C PF17655.1 EGG25353.1 - 0.017 14.7 0.5 0.053 13.1 0.5 1.8 1 0 0 1 1 1 0 Inward rectifier potassium channel C-terminal domain Pkinase PF00069.25 EGG25354.1 - 4.2e-19 68.9 0.0 9.7e-19 67.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG25354.1 - 0.098 11.9 0.1 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase Presenilin PF01080.17 EGG25354.1 - 5.4 5.7 4.7 7 5.3 4.7 1.2 1 0 0 1 1 1 0 Presenilin CEP63 PF17045.5 EGG25356.1 - 0.14 12.0 6.4 0.25 11.2 6.4 1.3 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa DUF2236 PF09995.9 EGG25357.1 - 9e-08 32.6 0.0 1.3e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) CCB1 PF12046.8 EGG25357.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B 7tm_3 PF00003.22 EGG25358.1 - 1.6e-13 51.0 17.9 1.3e-08 34.9 8.7 2.8 1 1 1 2 2 2 2 7 transmembrane sweet-taste receptor of 3 GCPR DUF3377 PF11857.8 EGG25358.1 - 0.21 11.6 2.2 9.2 6.3 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Insulin_TMD PF17870.1 EGG25358.1 - 0.31 11.2 11.0 0.34 11.0 0.7 3.5 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment RRM_1 PF00076.22 EGG25359.1 - 8.4e-46 153.7 5.4 2.6e-16 59.2 0.0 5.1 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoU_methylase PF00588.19 EGG25359.1 - 1.5e-24 86.8 0.0 3.8e-24 85.5 0.0 1.8 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EGG25359.1 - 2.4e-09 37.3 0.4 2e-08 34.4 0.1 2.4 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding RRM_occluded PF16842.5 EGG25359.1 - 0.0062 16.4 1.3 2.5 8.0 0.1 3.8 4 0 0 4 4 4 1 Occluded RNA-recognition motif Methyltrn_RNA_4 PF09936.9 EGG25359.1 - 0.0073 16.2 0.0 0.03 14.2 0.0 2.0 1 1 0 1 1 1 1 SAM-dependent RNA methyltransferase RRM_2 PF04059.12 EGG25359.1 - 0.053 13.7 0.1 0.27 11.5 0.0 2.2 2 1 0 2 2 2 0 RNA recognition motif 2 Pkinase PF00069.25 EGG25360.1 - 7.4e-62 209.1 2.2 1.7e-55 188.2 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGG25360.1 - 6.3e-37 127.3 0.1 6.7e-33 114.1 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase DUF3543 PF12063.8 EGG25360.1 - 1.5e-11 44.1 0.8 4.2e-11 42.7 0.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) MIT PF04212.18 EGG25360.1 - 0.00018 21.5 0.3 0.0018 18.3 0.2 2.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Pkinase_fungal PF17667.1 EGG25360.1 - 0.0022 16.9 0.2 0.0082 15.0 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGG25360.1 - 0.011 15.1 0.0 0.035 13.4 0.0 1.9 1 1 0 1 1 1 0 Kinase-like ABC1 PF03109.16 EGG25360.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 ABC1 family APH PF01636.23 EGG25360.1 - 0.014 15.3 0.0 0.037 13.9 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGG25360.1 - 0.016 14.6 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.6 EGG25361.1 - 0.042 13.9 3.1 2.1 8.6 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 EGG25361.1 - 1 10.2 4.1 8.8 7.3 0.3 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat Ribosomal_L7Ae PF01248.26 EGG25362.1 - 1.5e-24 85.5 2.0 2.1e-24 85.1 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Herpes_UL35 PF04496.12 EGG25363.1 - 0.07 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL35 family Fasciclin PF02469.22 EGG25363.1 - 0.075 13.3 2.1 0.1 12.8 2.1 1.3 1 0 0 1 1 1 0 Fasciclin domain SQHop_cyclase_N PF13249.6 EGG25363.1 - 0.092 11.8 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain IlvC PF01450.19 EGG25363.1 - 0.14 12.4 1.4 0.19 12.0 1.4 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain WD40 PF00400.32 EGG25364.1 - 1.4e-09 38.4 7.8 7.5e-07 29.8 0.2 5.5 6 0 0 6 6 6 1 WD domain, G-beta repeat WT1 PF02165.15 EGG25364.1 - 0.0028 16.9 2.7 0.0059 15.9 2.7 1.4 1 0 0 1 1 1 1 Wilm's tumour protein PQQ_3 PF13570.6 EGG25364.1 - 0.028 14.9 0.0 1.2 9.7 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain ANAPC4_WD40 PF12894.7 EGG25364.1 - 0.081 13.2 0.6 0.74 10.2 0.1 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SUIM_assoc PF16619.5 EGG25364.1 - 0.69 10.0 8.1 7.1 6.8 0.2 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Mlh1_C PF16413.5 EGG25365.1 - 6.6e-82 274.9 3.1 6.6e-82 274.9 3.1 3.8 3 1 0 3 3 3 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EGG25365.1 - 3.3e-29 101.0 1.3 7.7e-29 99.8 0.1 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain Longin PF13774.6 EGG25365.1 - 1.6e-15 56.9 0.6 3.7e-15 55.7 0.6 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain HATPase_c_3 PF13589.6 EGG25365.1 - 2.6e-11 43.5 0.0 2.6e-11 43.5 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGG25365.1 - 4.7e-07 30.3 0.1 1.4e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Myotub-related PF06602.14 EGG25367.1 - 2.6e-67 227.3 0.1 2.6e-67 227.3 0.1 3.0 3 0 0 3 3 3 1 Myotubularin-like phosphatase domain Pkinase_Tyr PF07714.17 EGG25367.1 - 1.1e-30 106.8 0.0 1.7e-24 86.5 0.0 3.6 2 1 0 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 EGG25367.1 - 7e-29 99.4 55.5 4.5e-08 32.7 2.4 7.5 3 1 3 6 6 6 6 Leucine rich repeat Pkinase PF00069.25 EGG25367.1 - 7.3e-25 87.8 0.0 2.5e-19 69.7 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain LRR_4 PF12799.7 EGG25367.1 - 1.3e-19 70.0 86.4 4.8e-06 26.8 3.9 10.2 5 1 4 10 10 10 8 Leucine Rich repeats (2 copies) COR PF16095.5 EGG25367.1 - 3.2e-09 36.9 0.2 2.7e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 EGG25367.1 - 7e-05 23.0 0.2 0.00033 20.8 0.2 2.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dus PF01207.17 EGG25369.1 - 1e-55 189.0 0.3 2.2e-55 188.0 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 EGG25369.1 - 3.2e-08 33.3 14.1 3.2e-05 23.7 0.1 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGG25369.1 - 2.1e-06 27.6 11.6 4.3e-05 23.4 0.8 2.7 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EGG25369.1 - 0.0002 21.0 0.8 0.0002 21.0 0.8 2.9 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 EGG25369.1 - 0.046 14.4 0.5 0.046 14.4 0.5 3.7 2 2 2 4 4 4 0 Torus domain zf-CCCH_2 PF14608.6 EGG25369.1 - 0.059 13.9 6.7 2.2 8.9 0.1 3.1 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger MgsA_C PF12002.8 EGG25369.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 MgsA AAA+ ATPase C terminal Folate_carrier PF01770.18 EGG25369.1 - 6.9 5.3 6.6 15 4.2 6.6 1.6 1 0 0 1 1 1 0 Reduced folate carrier PAP1 PF08601.10 EGG25369.1 - 7 6.3 28.5 0.085 12.6 19.2 2.0 2 0 0 2 2 2 0 Transcription factor PAP1 EGF_2 PF07974.13 EGG25370.1 - 0.074 13.4 31.4 0.07 13.5 8.4 2.8 2 0 0 2 2 2 0 EGF-like domain DUF3844 PF12955.7 EGG25370.1 - 7.3 6.8 12.7 9.8 6.4 2.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) PAC2 PF09754.9 EGG25372.1 - 1.2e-21 77.8 0.0 1.5e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 PAC2 family Notch PF00066.17 EGG25373.1 - 4.8e-62 206.1 187.6 2.9e-08 34.0 13.2 11.6 12 1 1 13 13 13 9 LNR domain UQ_con PF00179.26 EGG25375.1 - 2.7e-52 176.1 0.0 3.9e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGG25375.1 - 0.0044 17.3 0.0 0.0092 16.3 0.0 1.6 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EGG25375.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B TPR_2 PF07719.17 EGG25377.1 - 6e-13 47.8 0.4 1.4e-05 24.8 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGG25377.1 - 4.8e-12 45.2 1.4 6e-06 25.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGG25377.1 - 4.1e-09 36.0 1.6 8.8e-05 22.1 0.4 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 EGG25377.1 - 5.9e-05 23.0 1.6 0.051 13.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGG25377.1 - 0.0036 17.5 0.1 4.8 7.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGG25377.1 - 0.018 15.1 0.3 0.38 10.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGG25377.1 - 0.087 13.5 0.0 5.2 7.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGG25377.1 - 0.14 12.4 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat SpoIIIAH PF12685.7 EGG25378.1 - 0.12 12.1 0.6 0.18 11.6 0.6 1.4 1 1 0 1 1 1 0 SpoIIIAH-like protein TACC_C PF05010.14 EGG25379.1 - 6.9e-15 55.4 30.5 9.5e-14 51.7 12.6 6.6 3 2 2 5 5 5 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Abi_2 PF07751.11 EGG25379.1 - 0.14 12.4 0.2 0.14 12.4 0.2 3.8 4 0 0 4 4 4 0 Abi-like protein FlaC_arch PF05377.11 EGG25379.1 - 1.4 9.4 8.6 16 6.0 0.3 4.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) 7tm_2 PF00002.24 EGG25380.1 - 9.7e-05 21.8 7.9 9.7e-05 21.8 7.9 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Fz PF01392.22 EGG25380.1 - 0.003 18.2 0.9 0.0064 17.1 0.9 1.5 1 0 0 1 1 1 1 Fz domain Glyco_transf_20 PF00982.21 EGG25381.1 - 5.2e-182 605.8 0.0 6.4e-182 605.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGG25381.1 - 4.3e-29 101.3 0.0 9.1e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.20 EGG25381.1 - 0.0014 18.2 0.0 0.023 14.2 0.0 2.8 2 1 0 2 2 2 1 Glycosyl transferases group 1 Nucleoporin_FG PF13634.6 EGG25382.1 - 1.3e-09 38.7 173.4 0.0029 18.4 35.8 6.9 2 1 2 4 4 4 1 Nucleoporin FG repeat region Glyco_hydro_20 PF00728.22 EGG25383.1 - 2.7e-28 99.4 8.7 7.5e-12 45.3 0.1 4.1 1 1 2 3 3 3 3 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGG25383.1 - 4.9e-19 69.3 0.9 2e-17 64.1 0.0 2.9 2 1 0 2 2 2 1 beta-acetyl hexosaminidase like Cellulase PF00150.18 EGG25383.1 - 0.0053 16.2 0.1 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_97 PF10566.9 EGG25383.1 - 0.027 13.7 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase 97 Glyco_hydro_20b PF02838.15 EGG25383.1 - 0.031 15.0 0.0 0.099 13.4 0.0 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 Ras PF00071.22 EGG25384.1 - 8.4e-27 93.7 0.1 1.1e-26 93.3 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG25384.1 - 1.1e-14 54.7 0.0 1.9e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG25384.1 - 4.5e-07 29.5 0.0 5.7e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGG25384.1 - 2.4e-06 27.2 0.1 0.00057 19.5 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGG25384.1 - 0.00022 21.1 0.3 0.1 12.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGG25384.1 - 0.00034 20.7 0.0 0.00051 20.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGG25384.1 - 0.012 15.7 0.6 0.14 12.2 0.6 2.6 1 1 0 1 1 1 0 Dynamin family ABC_tran PF00005.27 EGG25384.1 - 0.013 16.0 0.1 0.031 14.8 0.0 1.7 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.10 EGG25384.1 - 0.015 14.7 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGG25384.1 - 0.023 13.9 0.5 0.34 10.0 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 EGG25384.1 - 0.048 13.4 1.3 0.19 11.5 0.3 2.3 2 1 1 3 3 3 0 P-loop containing region of AAA domain AATase PF07247.12 EGG25385.1 - 4.8e-09 35.3 0.1 4.3e-06 25.6 0.0 2.1 1 1 1 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.20 EGG25385.1 - 0.00012 20.9 0.1 0.68 8.5 0.1 3.0 2 1 1 3 3 3 3 Condensation domain TIMELESS PF04821.14 EGG25386.1 - 2.6e-38 131.9 1.1 2.6e-38 131.9 1.1 3.9 4 2 0 4 4 4 1 Timeless protein Sugar_tr PF00083.24 EGG25387.1 - 2.9e-88 296.7 41.7 9.2e-87 291.8 41.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGG25387.1 - 6.1e-36 124.1 60.1 6.3e-28 97.7 34.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 2OG-FeII_Oxy_3 PF13640.6 EGG25388.1 - 5.2e-06 27.3 0.1 0.016 16.1 0.1 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily E3_UFM1_ligase PF09743.9 EGG25389.1 - 2e-96 322.8 8.8 2e-96 322.8 8.8 2.8 3 0 0 3 3 3 1 E3 UFM1-protein ligase 1 Tup_N PF08581.10 EGG25389.1 - 0.086 13.2 0.3 0.086 13.2 0.3 3.8 4 0 0 4 4 4 0 Tup N-terminal DUF5405 PF17399.2 EGG25389.1 - 0.16 12.2 2.2 2.3 8.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5405) DDRGK PF09756.9 EGG25389.1 - 0.81 9.3 0.0 0.81 9.3 0.0 4.1 5 0 0 5 5 5 0 DDRGK domain HEAT PF02985.22 EGG25390.1 - 9.8e-44 143.6 19.1 0.00017 21.6 0.0 13.6 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 EGG25390.1 - 9.2e-35 118.9 0.2 2.5e-10 40.6 0.0 7.6 3 1 5 8 8 8 5 HEAT repeats HEAT_EZ PF13513.6 EGG25390.1 - 1.4e-12 47.8 6.0 0.00035 21.0 0.0 7.2 8 0 0 8 8 8 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGG25390.1 - 2e-10 41.1 0.3 2 9.0 0.0 6.6 4 2 2 7 7 7 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EGG25390.1 - 7e-09 34.8 5.2 0.043 12.4 0.9 3.8 2 1 1 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 EGG25390.1 - 8.6e-09 35.6 6.6 0.0032 17.5 0.9 4.8 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGG25390.1 - 3.8e-07 29.9 0.2 0.016 14.7 0.0 5.0 3 1 2 5 5 5 2 CLASP N terminal Arm PF00514.23 EGG25390.1 - 0.039 14.0 8.3 21 5.4 0.0 7.5 10 0 0 10 10 10 0 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 EGG25390.1 - 0.18 11.9 0.2 2 8.5 0.0 2.8 3 0 0 3 3 3 0 V-ATPase subunit H PGAP1 PF07819.13 EGG25391.1 - 1.5e-72 244.1 1.3 4.3e-72 242.6 0.1 2.1 2 0 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 EGG25391.1 - 0.0031 17.4 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 EGG25391.1 - 0.005 17.5 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGG25391.1 - 0.016 14.5 0.1 0.068 12.4 0.0 2.0 3 0 0 3 3 3 0 Serine aminopeptidase, S33 SPECT1 PF18680.1 EGG25391.1 - 0.06 13.0 0.0 0.2 11.3 0.0 1.9 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 DUF676 PF05057.14 EGG25391.1 - 0.081 12.4 0.2 0.18 11.3 0.2 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) SUIM_assoc PF16619.5 EGG25391.1 - 0.084 13.0 15.4 2.2 8.4 0.5 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Esterase PF00756.20 EGG25391.1 - 0.097 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative esterase DUF4577 PF15145.6 EGG25391.1 - 0.4 10.7 2.2 5.7 7.0 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) polyprenyl_synt PF00348.17 EGG25392.1 - 4.6e-70 235.6 0.1 8.1e-70 234.8 0.1 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EGG25392.1 - 0.00063 19.4 0.2 0.0014 18.2 0.2 1.5 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Syntaphilin PF15290.6 EGG25392.1 - 0.047 13.3 3.2 0.098 12.3 3.2 1.5 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp CDC37_C PF08564.10 EGG25392.1 - 0.12 12.5 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 Cdc37 C terminal domain DUF2967 PF11179.8 EGG25392.1 - 0.17 10.0 4.4 0.24 9.5 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) NmrA PF05368.13 EGG25393.1 - 2e-15 57.0 0.0 6e-15 55.4 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGG25393.1 - 2.1e-13 50.6 0.0 4.9e-12 46.1 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGG25393.1 - 0.00016 21.2 0.0 0.0003 20.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TFIIA PF03153.13 EGG25394.1 - 0.48 10.4 38.2 0.023 14.7 32.9 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FlpD PF02662.16 EGG25395.1 - 0.092 12.7 0.1 0.15 12.1 0.1 1.4 1 1 1 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit Methyltransf_11 PF08241.12 EGG25396.1 - 1.3e-22 80.2 0.0 2.8e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGG25396.1 - 6.2e-22 78.0 0.0 9.6e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGG25396.1 - 8.3e-21 74.5 0.0 1.6e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGG25396.1 - 1.5e-14 53.9 0.0 2.3e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGG25396.1 - 1.6e-13 50.8 0.0 2.5e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGG25396.1 - 3.6e-12 46.9 0.0 7.8e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGG25396.1 - 6.9e-09 35.8 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EGG25396.1 - 4.2e-08 33.0 0.0 7.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 EGG25396.1 - 2.6e-06 26.9 0.0 3.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Fibrillarin PF01269.17 EGG25396.1 - 0.00014 21.0 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_4 PF02390.17 EGG25396.1 - 0.00091 18.7 0.1 0.0022 17.5 0.0 1.7 2 1 0 2 2 2 1 Putative methyltransferase Pox_MCEL PF03291.16 EGG25396.1 - 0.0034 16.6 0.0 0.021 14.0 0.0 1.9 1 1 1 2 2 2 1 mRNA capping enzyme GCD14 PF08704.10 EGG25396.1 - 0.0073 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_32 PF13679.6 EGG25396.1 - 0.008 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGG25396.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGG25396.1 - 0.025 14.1 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 EGG25396.1 - 0.052 12.5 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) FtsJ PF01728.19 EGG25396.1 - 0.065 13.3 0.1 0.15 12.1 0.1 1.8 2 1 0 2 2 1 0 FtsJ-like methyltransferase TehB PF03848.14 EGG25396.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB RRM_1 PF00076.22 EGG25397.1 - 2e-17 62.8 0.0 3.8e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mgm101p PF06420.12 EGG25398.1 - 9.5e-71 236.8 0.0 1.5e-70 236.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Histone PF00125.24 EGG25398.1 - 0.1 12.9 0.2 0.1 12.9 0.2 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Velvet PF11754.8 EGG25398.1 - 0.13 12.1 8.8 0.16 11.9 1.8 2.1 2 0 0 2 2 2 0 Velvet factor Pescadillo_N PF06732.11 EGG25399.1 - 1.3e-106 356.2 3.1 1.3e-106 356.2 3.1 2.4 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EGG25399.1 - 1.5e-09 38.1 0.2 6e-09 36.2 0.2 2.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RWP-RK PF02042.15 EGG25399.1 - 0.92 9.5 4.6 16 5.6 0.5 2.6 2 0 0 2 2 2 0 RWP-RK domain bMG10 PF17973.1 EGG25400.1 - 3.7e-24 85.4 0.0 1.1e-23 83.8 0.0 2.0 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain ubiquitin PF00240.23 EGG25400.1 - 1e-16 60.4 1.6 1.2e-06 28.1 0.1 3.9 3 0 0 3 3 3 2 Ubiquitin family MG2 PF01835.19 EGG25400.1 - 3.6e-11 43.4 0.0 7.9e-07 29.5 0.0 4.1 4 0 0 4 4 4 1 MG2 domain A2M PF00207.22 EGG25400.1 - 3.9e-11 42.7 0.1 4.7e-10 39.2 0.1 2.8 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 EGG25400.1 - 2.6e-05 24.6 0.2 0.00016 22.0 0.1 2.6 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain Rad60-SLD PF11976.8 EGG25400.1 - 3.9e-05 23.4 0.8 0.021 14.7 0.0 3.6 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Big_1 PF02369.16 EGG25400.1 - 5.1e-05 23.2 0.1 0.0013 18.7 0.2 3.0 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 1) MG4 PF17789.1 EGG25400.1 - 0.011 15.9 0.3 4.3 7.5 0.1 3.9 2 1 0 2 2 2 0 Macroglobulin domain MG4 Big_5 PF13205.6 EGG25400.1 - 0.041 14.6 0.0 0.041 14.6 0.0 5.0 5 1 1 6 6 6 0 Bacterial Ig-like domain CarboxypepD_reg PF13620.6 EGG25400.1 - 0.13 12.6 0.4 2.2 8.6 0.1 3.2 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain YtkA PF13115.6 EGG25400.1 - 0.15 12.7 1.3 0.91 10.2 0.2 2.9 2 0 0 2 2 2 0 YtkA-like DUF824 PF05688.11 EGG25400.1 - 1.4 8.8 3.0 1.2 9.1 0.1 2.5 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) XPG_N PF00752.17 EGG25401.1 - 1e-25 90.1 0.0 2.4e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGG25401.1 - 3.5e-21 75.4 0.1 3.5e-21 75.4 0.1 3.1 3 0 0 3 3 3 1 XPG I-region XPG_I_2 PF12813.7 EGG25401.1 - 9e-07 28.6 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 EGG25401.1 - 0.0082 16.7 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_2 PF07719.17 EGG25401.1 - 0.013 15.6 0.5 0.029 14.5 0.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PKD_channel PF08016.12 EGG25402.1 - 1.3e-09 37.2 9.5 2.3e-09 36.4 9.5 1.3 1 0 0 1 1 1 1 Polycystin cation channel MCPVI PF02993.14 EGG25402.1 - 0.15 11.9 2.3 0.26 11.1 2.3 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Corazonin PF17308.2 EGG25402.1 - 0.27 11.6 10.1 0.72 10.2 10.1 1.7 1 0 0 1 1 1 0 Pro-corazonin Tyr_Deacylase PF02580.16 EGG25403.1 - 3.3e-46 157.4 0.0 3.7e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase MdcG PF10620.9 EGG25403.1 - 0.15 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG IF-2B PF01008.17 EGG25404.1 - 6.9e-72 242.0 0.0 1.1e-71 241.3 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family Cytochrom_C1 PF02167.15 EGG25404.1 - 0.028 14.2 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 Cytochrome C1 family Ras PF00071.22 EGG25405.1 - 6.4e-35 120.2 0.2 7.6e-35 119.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGG25405.1 - 6.1e-26 91.0 0.1 9.3e-26 90.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGG25405.1 - 2.7e-08 33.5 0.0 3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGG25405.1 - 3.7e-06 26.5 0.2 4.7e-06 26.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EGG25405.1 - 0.0035 16.2 0.4 1.3 7.8 0.0 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 EGG25405.1 - 0.0097 15.1 1.5 0.062 12.4 0.3 2.4 1 1 1 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.9 EGG25405.1 - 0.031 14.0 0.3 0.071 12.8 0.3 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGG25405.1 - 0.07 12.6 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NadA PF02445.16 EGG25405.1 - 0.095 11.8 0.1 8.1 5.5 0.0 2.1 2 0 0 2 2 2 0 Quinolinate synthetase A protein MMR_HSR1 PF01926.23 EGG25405.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 EGG25405.1 - 0.18 11.2 0.0 1.6 8.1 0.0 2.2 2 1 1 3 3 3 0 Bacterial TniB protein Pkinase PF00069.25 EGG25406.1 - 2.9e-63 213.7 0.0 5.2e-63 212.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGG25406.1 - 3.3e-49 167.5 0.0 4.7e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGG25406.1 - 0.0011 17.8 0.0 0.0022 16.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase KIND PF16474.5 EGG25406.1 - 0.043 13.7 0.1 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain Kinase-like PF14531.6 EGG25406.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGG25406.1 - 0.23 11.3 0.0 0.44 10.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LIM PF00412.22 EGG25407.1 - 2.3e-30 104.6 39.7 1.3e-10 41.4 7.2 3.3 3 0 0 3 3 3 3 LIM domain WH2 PF02205.20 EGG25407.1 - 9e-11 41.3 0.5 6.7e-10 38.5 0.2 2.3 2 0 0 2 2 2 1 WH2 motif zf-P11 PF03854.14 EGG25407.1 - 0.014 15.0 2.5 0.014 15.0 2.5 3.4 3 1 0 3 3 3 0 P-11 zinc finger zf-C3HC4_3 PF13920.6 EGG25407.1 - 0.09 12.7 35.7 0.11 12.3 6.7 4.9 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Uroplakin_II PF07353.12 EGG25408.1 - 0.01 15.4 0.2 0.02 14.4 0.2 1.4 1 0 0 1 1 1 0 Uroplakin II putAbiC PF16872.5 EGG25408.1 - 0.041 14.6 0.9 5.2 7.8 0.1 3.8 3 0 0 3 3 3 0 Putative phage abortive infection protein Ank_2 PF12796.7 EGG25408.1 - 0.076 13.6 0.2 3.9 8.1 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) UBA PF00627.31 EGG25409.1 - 2.9e-07 30.3 0.7 1.1e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain STI1 PF17830.1 EGG25409.1 - 0.0048 16.8 8.8 0.0048 16.8 8.8 4.6 3 2 1 4 4 4 1 STI1 domain HOIP-UBA PF16678.5 EGG25409.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 HOIP UBA domain pair RsmJ PF04378.13 EGG25409.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ DUF3410 PF11890.8 EGG25409.1 - 0.14 12.0 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) DUF2065 PF09838.9 EGG25409.1 - 0.76 9.8 5.4 2.3 8.3 0.1 3.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2065) TetR_C_19 PF17924.1 EGG25409.1 - 1.7 9.2 6.6 1.4 9.5 2.2 2.4 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CENP-B_dimeris PF09026.10 EGG25410.1 - 3.9 7.9 16.2 2.6 8.5 9.5 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain VASt PF16016.5 EGG25411.1 - 2.6e-21 76.6 0.2 7.1e-21 75.2 0.2 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EGG25411.1 - 0.0019 18.1 0.4 0.25 11.2 0.2 2.8 1 1 1 2 2 2 1 GRAM domain DUF1387 PF07139.11 EGG25411.1 - 0.99 9.1 13.4 11 5.6 10.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) MAP70 PF07058.11 EGG25411.1 - 3 6.5 9.0 4.5 5.9 9.0 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 PRP1_N PF06424.12 EGG25412.1 - 0.086 13.2 5.3 0.12 12.8 5.3 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Dynactin_p62 PF05502.13 EGG25412.1 - 0.33 9.7 8.0 0.36 9.5 8.0 1.0 1 0 0 1 1 1 0 Dynactin p62 family Paramyxo_ncap PF00973.19 EGG25412.1 - 0.47 9.3 6.2 0.53 9.1 6.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Pex14_N PF04695.13 EGG25412.1 - 0.76 10.4 4.9 1.1 10.0 4.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ALMT PF11744.8 EGG25412.1 - 0.88 8.3 11.5 0.92 8.3 11.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3537 PF12056.8 EGG25412.1 - 1.2 7.9 5.3 1.3 7.7 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Menin PF05053.13 EGG25412.1 - 2.3 6.5 12.8 2.9 6.2 12.8 1.2 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 EGG25412.1 - 3.1 6.5 11.3 3.7 6.2 11.3 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 EGG25412.1 - 6.4 6.8 7.1 7.4 6.6 7.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HCO3_cotransp PF00955.21 EGG25412.1 - 7 5.4 6.7 7.2 5.3 6.7 1.1 1 0 0 1 1 1 0 HCO3- transporter family O-antigen_lig PF13425.6 EGG25412.1 - 7.4 5.2 6.9 7.6 5.2 6.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF1676 PF07898.13 EGG25412.1 - 9.2 6.3 6.1 12 5.9 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) Mnd1 PF03962.15 EGG25414.1 - 8.5e-17 61.2 0.1 1.9e-16 60.1 0.1 1.6 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 EGG25414.1 - 3.6e-09 36.6 1.5 1.5e-08 34.6 0.1 2.6 1 1 1 2 2 2 1 Leucine zipper with capping helix domain FapA PF03961.13 EGG25414.1 - 0.0034 16.1 7.3 0.0056 15.3 7.3 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A Nsp1_C PF05064.13 EGG25414.1 - 0.048 13.5 3.7 0.079 12.8 3.7 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region RNase_T PF00929.24 EGG25415.1 - 9.3e-26 91.3 0.0 1.4e-25 90.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease FixH PF05751.11 EGG25416.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 1 0 1 1 1 0 FixH Gtr1_RagA PF04670.12 EGG25417.1 - 0.0026 17.1 0.1 0.0026 17.1 0.1 2.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGG25417.1 - 0.014 15.3 1.0 0.014 15.3 1.0 4.4 6 1 1 7 7 7 0 RsgA GTPase Sigma54_activat PF00158.26 EGG25417.1 - 0.015 15.0 0.2 0.034 13.9 0.2 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.23 EGG25417.1 - 0.047 13.8 0.1 0.047 13.8 0.1 7.3 4 4 1 5 5 5 0 Dynamin family ABC_tran PF00005.27 EGG25417.1 - 0.049 14.1 0.2 0.049 14.1 0.2 4.4 4 1 0 4 4 4 0 ABC transporter AAA_29 PF13555.6 EGG25417.1 - 0.095 12.5 1.2 0.2 11.4 0.5 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain USP8_interact PF08941.10 EGG25417.1 - 3.7 7.3 6.6 13 5.5 0.0 2.9 2 0 0 2 2 2 0 USP8 interacting RsgA_GTPase PF03193.16 EGG25418.1 - 0.0096 15.8 0.1 0.029 14.3 0.1 1.8 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EGG25418.1 - 0.04 14.0 2.3 0.047 13.8 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EGG25418.1 - 0.096 13.2 0.0 0.096 13.2 0.0 3.7 3 2 0 3 3 3 0 ABC transporter DUF1654 PF07867.11 EGG25418.1 - 0.18 11.5 22.9 0.31 10.8 0.1 5.8 4 1 1 5 5 5 0 Protein of unknown function (DUF1654) AIG1 PF04548.16 EGG25419.1 - 0.00012 21.4 1.2 0.00012 21.4 1.2 2.9 3 1 0 3 3 3 1 AIG1 family Mucin PF01456.17 EGG25419.1 - 1.6 8.8 23.6 5 7.1 12.6 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Abi_C PF14355.6 EGG25419.1 - 4.4 7.5 7.3 0.69 10.1 0.5 3.1 3 0 0 3 3 3 0 Abortive infection C-terminus LMBR1 PF04791.16 EGG25419.1 - 6.9 5.5 6.7 9.9 4.9 6.7 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein EGF_2 PF07974.13 EGG25420.1 - 0.063 13.7 11.5 0.19 12.1 11.5 1.9 1 0 0 1 1 1 0 EGF-like domain Insulin_TMD PF17870.1 EGG25420.1 - 0.088 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PCC_BT PF18140.1 EGG25420.1 - 0.24 11.7 0.5 9.5 6.6 0.0 2.6 2 0 0 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain Coat_X PF07552.11 EGG25420.1 - 8.9 6.2 9.1 0.43 10.4 0.4 3.0 3 0 0 3 3 3 0 Spore Coat Protein X and V domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Dictyostelium_fasciculatum-DFas_2.0/GCA_000203815.1_DFas_2.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Dictyostelium_fasciculatum-DFas_2.0/GCA_000203815.1_DFas_2.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Dictyostelium_fasciculatum-DFas_2.0/GCA_000203815.1_DFas_2.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Dictyostelium_fasciculatum-DFas_2.0/GCA_000203815.1_DFas_2.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 10:36:25 2019 # [ok]